CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 Pfam PF02132 RecR protein 40 79 1.5E-15 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 Gene3D G3DSA:3.40.1360.10 78 171 6.5E-41 T 29-03-2018 CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 Pfam PF13662 Toprim domain 81 172 7.9E-27 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 SMART SM00493 81 166 2.0E-17 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 SUPERFAMILY SSF111304 4 199 1.83E-78 T 29-03-2018 IPR023627 Recombination protein RecR CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 111.439 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 TIGRFAM TIGR00615 recR: recombination protein RecR 3 197 2.0E-87 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CWR56_RS18580 6b947abfe82de700ed89c383926679ff 199 Gene3D G3DSA:1.10.150.20 9 72 3.8E-4 T 29-03-2018 CWR56_RS08115 af697b515771469d9926ca50b32b5680 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 148 4.0E-60 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08115 af697b515771469d9926ca50b32b5680 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 149 5.4E-62 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08115 af697b515771469d9926ca50b32b5680 153 Gene3D G3DSA:3.40.50.960 1 153 1.5E-69 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08115 af697b515771469d9926ca50b32b5680 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 152 30.736 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08115 af697b515771469d9926ca50b32b5680 153 SUPERFAMILY SSF52121 2 152 4.32E-66 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS04505 3c7859d90e25bfa769e412e9622c331f 171 Pfam PF03061 Thioesterase superfamily 57 128 1.8E-8 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CWR56_RS04505 3c7859d90e25bfa769e412e9622c331f 171 Gene3D G3DSA:3.10.129.10 3 144 8.7E-25 T 29-03-2018 CWR56_RS04505 3c7859d90e25bfa769e412e9622c331f 171 SUPERFAMILY SSF54637 16 140 7.78E-31 T 29-03-2018 IPR029069 HotDog domain CWR56_RS00615 b14ffb966242615d4e00dd4086bbe835 175 Pfam PF06866 Protein of unknown function (DUF1256) 12 168 4.0E-56 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CWR56_RS00615 b14ffb966242615d4e00dd4086bbe835 175 SUPERFAMILY SSF53163 11 172 2.41E-41 T 29-03-2018 IPR023430 Peptidase HybD-like domain CWR56_RS00615 b14ffb966242615d4e00dd4086bbe835 175 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 34 170 1.4E-41 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CWR56_RS00615 b14ffb966242615d4e00dd4086bbe835 175 Gene3D G3DSA:3.40.50.1450 8 144 4.3E-29 T 29-03-2018 IPR023430 Peptidase HybD-like domain CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 SUPERFAMILY SSF46689 170 217 8.96E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 SMART SM00342 184 266 4.2E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 Gene3D G3DSA:2.60.120.280 17 177 1.3E-15 T 29-03-2018 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 262 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 Pfam PF12833 Helix-turn-helix domain 191 267 1.5E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 Gene3D G3DSA:1.10.10.60 178 220 2.4E-11 T 29-03-2018 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 Gene3D G3DSA:1.10.10.60 221 272 2.4E-10 T 29-03-2018 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 Pfam PF02311 AraC-like ligand binding domain 16 133 1.3E-18 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 SUPERFAMILY SSF46689 220 268 5.38E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS05995 42a73617a21038650b08e4f37780bbbe 278 SUPERFAMILY SSF51215 14 153 3.01E-24 T 29-03-2018 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 4.6E-51 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 2.8E-25 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 Gene3D G3DSA:3.40.50.2020 146 316 1.2E-45 T 29-03-2018 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 316 1.6E-124 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 SMART SM01400 8 124 5.5E-82 T 29-03-2018 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 132 147 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 8 316 48.904 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 SUPERFAMILY SSF53271 73 308 8.14E-66 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS17525 960049cd4e38d5a2e2db5b68917b1e39 316 Gene3D G3DSA:3.40.50.2020 8 145 1.8E-61 T 29-03-2018 CWR56_RS06745 c0951182045f6a990ef903cb443dddf9 463 Gene3D G3DSA:1.25.40.10 49 285 3.9E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05225 741e245d72f87ae6db51633c9916fb50 94 Pfam PF03776 Septum formation topological specificity factor MinE 15 87 1.9E-24 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CWR56_RS05225 741e245d72f87ae6db51633c9916fb50 94 Gene3D G3DSA:3.30.1070.10 2 88 5.4E-29 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CWR56_RS05225 741e245d72f87ae6db51633c9916fb50 94 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 2 88 4.7E-22 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CWR56_RS05225 741e245d72f87ae6db51633c9916fb50 94 SUPERFAMILY SSF55229 32 90 1.57E-10 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CWR56_RS05225 741e245d72f87ae6db51633c9916fb50 94 Hamap MF_00262 Cell division topological specificity factor [minE]. 1 92 16.636 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 201 237 2.04E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 485 494 2.04E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 530 594 2.04E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 344 352 2.04E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 386 429 2.04E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 17 654 0.0 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 PIRSF PIRSF000906 11 657 0.0 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 200 249 8.86E-7 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 SUPERFAMILY SSF56300 48 72 8.86E-7 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 Gene3D G3DSA:3.60.21.10 9 612 1.1E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05430 fd23e0498de61e6f05d24793200812d3 661 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 15 656 40.134 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 Gene3D G3DSA:3.30.70.920 52 141 7.3E-23 T 29-03-2018 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 SUPERFAMILY SSF46785 1 60 1.12E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 SMART SM00344 1 107 5.8E-37 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 4.7E-18 T 29-03-2018 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 Pfam PF01037 Lrp/AsnC ligand binding domain 67 134 2.0E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 SUPERFAMILY SSF54909 64 136 3.04E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CWR56_RS17670 1da05722ae05a838b1b18ad4a33501fd 142 Gene3D G3DSA:1.10.10.10 2 51 2.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08255 eb083f720faf0e2ec0e32728e17bfabf 269 SUPERFAMILY SSF46689 209 259 9.41E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08255 eb083f720faf0e2ec0e32728e17bfabf 269 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 252 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS08255 eb083f720faf0e2ec0e32728e17bfabf 269 Pfam PF12833 Helix-turn-helix domain 181 257 1.8E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS08255 eb083f720faf0e2ec0e32728e17bfabf 269 Gene3D G3DSA:1.10.10.60 207 261 1.7E-11 T 29-03-2018 CWR56_RS08255 eb083f720faf0e2ec0e32728e17bfabf 269 SMART SM00342 173 256 2.9E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS08255 eb083f720faf0e2ec0e32728e17bfabf 269 Gene3D G3DSA:1.10.10.60 3 206 2.9E-7 T 29-03-2018 CWR56_RS03880 d56be586f3ab332fc8455333d46f8e1f 251 Pfam PF02540 NAD synthase 8 245 3.0E-69 T 29-03-2018 IPR022310 NAD/GMP synthase CWR56_RS03880 d56be586f3ab332fc8455333d46f8e1f 251 SUPERFAMILY SSF52402 3 250 4.44E-68 T 29-03-2018 CWR56_RS03880 d56be586f3ab332fc8455333d46f8e1f 251 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 1 248 31.399 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CWR56_RS03880 d56be586f3ab332fc8455333d46f8e1f 251 Gene3D G3DSA:3.40.50.620 3 250 5.3E-55 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS03880 d56be586f3ab332fc8455333d46f8e1f 251 TIGRFAM TIGR00552 nadE: NAD+ synthetase 10 247 1.0E-72 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 7.7E-7 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 7.7E-7 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 SUPERFAMILY SSF64518 177 433 4.45E-19 T 29-03-2018 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 Pfam PF00460 Flagella basal body rod protein 8 37 2.2E-7 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 224 2.8E-58 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 Gene3D G3DSA:1.20.1170.10 4 429 0.0019 T 29-03-2018 CWR56_RS01165 e33b19556c26e802ce3d5102c2076ce5 436 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 376 433 1.8E-14 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 Pfam PF13484 4Fe-4S double cluster binding domain 178 242 2.3E-15 T 29-03-2018 CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 Gene3D G3DSA:3.30.70.20 232 296 0.14 T 29-03-2018 CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 178 189 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 301 3.9E-74 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 Pfam PF08331 Domain of unknown function (DUF1730) 53 124 8.4E-15 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 Gene3D G3DSA:3.30.70.20 189 231 7.5E-8 T 29-03-2018 CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 Gene3D G3DSA:3.30.70.20 111 188 6.3E-4 T 29-03-2018 CWR56_RS02600 894e899d77b68725f4a3c9dcf98d7cc8 304 SUPERFAMILY SSF54862 171 256 6.28E-14 T 29-03-2018 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 SUPERFAMILY SSF56327 170 443 5.94E-83 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 SUPERFAMILY SSF51735 5 166 6.02E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 7 22 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 2.6E-51 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 Gene3D G3DSA:3.90.1820.10 3 274 9.5E-62 T 29-03-2018 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 Gene3D G3DSA:3.90.1820.10 275 443 6.6E-45 T 29-03-2018 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 Pfam PF02056 Family 4 glycosyl hydrolase 8 186 5.8E-61 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CWR56_RS15255 4bf257f702e347397d37b5adb3b33d85 443 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 418 6.8E-51 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CWR56_RS14710 96c7ac2a2f8736f1db9f6c5af36ab039 325 Pfam PF01992 ATP synthase (C/AC39) subunit 11 319 2.9E-67 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14710 96c7ac2a2f8736f1db9f6c5af36ab039 325 Gene3D G3DSA:1.20.1690.10 179 274 1.0E-8 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14710 96c7ac2a2f8736f1db9f6c5af36ab039 325 Gene3D G3DSA:1.20.1690.10 79 174 2.0E-18 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14710 96c7ac2a2f8736f1db9f6c5af36ab039 325 SUPERFAMILY SSF103486 7 321 3.01E-59 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 539 1.9E-43 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 SUPERFAMILY SSF52518 369 560 6.49E-56 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 Gene3D G3DSA:3.40.50.970 349 561 3.0E-42 T 29-03-2018 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 SUPERFAMILY SSF52518 2 173 1.6E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 337 2.9E-44 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 171 4.3E-57 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 SUPERFAMILY SSF52467 198 360 2.27E-55 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 Gene3D G3DSA:3.40.50.970 1 190 1.3E-59 T 29-03-2018 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 562 2.4E-211 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CWR56_RS07425 9eed0b6ac70b25bef3647483b15dd448 564 Gene3D G3DSA:3.40.50.1220 194 348 1.1E-45 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS18845 8a1c1b7413b2f54968afe1bcba193dd8 164 Gene3D G3DSA:2.20.25.10 69 96 0.0056 T 29-03-2018 CWR56_RS18845 8a1c1b7413b2f54968afe1bcba193dd8 164 Gene3D G3DSA:2.20.25.10 2 40 0.12 T 29-03-2018 CWR56_RS18845 8a1c1b7413b2f54968afe1bcba193dd8 164 PIRSF PIRSF015034 1 164 4.9E-54 T 29-03-2018 IPR025542 YacH protein CWR56_RS18845 8a1c1b7413b2f54968afe1bcba193dd8 164 Gene3D G3DSA:4.10.860.10 97 163 3.4E-11 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS18845 8a1c1b7413b2f54968afe1bcba193dd8 164 Pfam PF02151 UvrB/uvrC motif 127 160 5.0E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS18845 8a1c1b7413b2f54968afe1bcba193dd8 164 SUPERFAMILY SSF46600 121 160 9.29E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS07670 d054224fa008446ad6cb2915e0cbd86f 264 SMART SM00382 49 232 6.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07670 d054224fa008446ad6cb2915e0cbd86f 264 Gene3D G3DSA:3.40.50.300 1 263 6.8E-64 T 29-03-2018 CWR56_RS07670 d054224fa008446ad6cb2915e0cbd86f 264 Pfam PF00005 ABC transporter 40 183 7.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07670 d054224fa008446ad6cb2915e0cbd86f 264 SUPERFAMILY SSF52540 24 247 5.97E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 PRINTS PR01576 Peptide deformylase signature 33 62 8.7E-34 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 PRINTS PR01576 Peptide deformylase signature 117 146 8.7E-34 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 PRINTS PR01576 Peptide deformylase signature 86 97 8.7E-34 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 PRINTS PR01576 Peptide deformylase signature 98 116 8.7E-34 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 146 2.7E-49 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 Pfam PF01327 Polypeptide deformylase 4 146 6.0E-49 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 Hamap MF_00163 Peptide deformylase [def]. 2 146 28.207 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 SUPERFAMILY SSF56420 3 145 4.58E-56 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 PIRSF PIRSF004749 1 146 4.7E-51 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS13070 8e5107cd42b483367de832cdd0d01354 146 Gene3D G3DSA:3.90.45.10 1 146 8.5E-59 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Gene3D G3DSA:3.30.70.870 304 402 5.4E-29 T 29-03-2018 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 SUPERFAMILY SSF50447 153 302 5.52E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Gene3D G3DSA:3.40.50.300 70 184 4.0E-29 T 29-03-2018 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Gene3D G3DSA:3.30.70.240 403 480 3.8E-18 T 29-03-2018 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Gene3D G3DSA:2.40.30.10 185 302 8.9E-24 T 29-03-2018 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 2.6E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 SUPERFAMILY SSF54980 400 513 1.34E-21 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 SUPERFAMILY SSF52540 3 208 1.23E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 147 6.7E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 SUPERFAMILY SSF54980 305 389 1.19E-14 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 SMART SM00838 397 484 4.3E-5 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 PRINTS PR00315 GTP-binding elongation factor signature 125 134 8.4E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 PRINTS PR00315 GTP-binding elongation factor signature 9 22 8.4E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 PRINTS PR00315 GTP-binding elongation factor signature 73 83 8.4E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 PRINTS PR00315 GTP-binding elongation factor signature 53 61 8.4E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 597 7.2E-262 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Gene3D G3DSA:3.40.50.300 1 69 1.7E-11 T 29-03-2018 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Gene3D G3DSA:2.40.50.250 483 573 6.6E-35 T 29-03-2018 CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Pfam PF00679 Elongation factor G C-terminus 398 481 3.5E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS10175 b236964b2f77292df5a8fd109a1b1120 607 Pfam PF03144 Elongation factor Tu domain 2 221 291 1.4E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS06525 16b3567f265e075d370e3d0b76cbc0ea 264 Gene3D G3DSA:3.30.1360.130 211 264 7.1E-4 T 29-03-2018 CWR56_RS06525 16b3567f265e075d370e3d0b76cbc0ea 264 PIRSF PIRSF015853 1 264 2.0E-74 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CWR56_RS06525 16b3567f265e075d370e3d0b76cbc0ea 264 Pfam PF04951 D-aminopeptidase 1 262 3.0E-88 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CWR56_RS06525 16b3567f265e075d370e3d0b76cbc0ea 264 Gene3D G3DSA:3.40.50.10780 1 210 8.7E-70 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal CWR56_RS06525 16b3567f265e075d370e3d0b76cbc0ea 264 SUPERFAMILY SSF63992 1 263 1.19E-75 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 Pfam PF16916 Dimerisation domain of Zinc Transporter 229 304 2.9E-12 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 Gene3D G3DSA:3.30.70.1350 224 312 3.1E-15 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 SUPERFAMILY SSF160240 227 306 1.57E-16 T 29-03-2018 CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 Gene3D G3DSA:1.20.1510.10 30 223 5.5E-43 T 29-03-2018 CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 Pfam PF01545 Cation efflux family 33 224 1.5E-49 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 Gene3D G3DSA:3.30.70.1350 313 390 3.4E-9 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 32 302 6.6E-66 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS14375 f8141a653f29b4ab7aaddc7653bc83ee 392 SUPERFAMILY SSF161111 24 225 3.53E-54 T 29-03-2018 CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 Hamap MF_01469 Ribonuclease M5 [rnmV]. 1 175 31.017 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 SUPERFAMILY SSF110455 1 114 2.12E-33 T 29-03-2018 CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 Pfam PF13331 Domain of unknown function (DUF4093) 89 173 3.8E-26 T 29-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 174 2.6E-48 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 Gene3D G3DSA:3.40.1360.20 1 122 2.1E-24 T 29-03-2018 CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 SMART SM00493 3 76 1.7E-9 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS17575 da51d495348951d30b929afe3047b7ca 176 Pfam PF13662 Toprim domain 3 69 6.3E-6 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS15100 b59a0f132ac97f096b27d8eab7bedfa9 394 Pfam PF00155 Aminotransferase class I and II 49 382 1.7E-37 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS15100 b59a0f132ac97f096b27d8eab7bedfa9 394 Gene3D G3DSA:3.40.640.10 92 270 1.8E-21 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS15100 b59a0f132ac97f096b27d8eab7bedfa9 394 Gene3D G3DSA:3.90.1150.10 1 91 2.6E-10 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS15100 b59a0f132ac97f096b27d8eab7bedfa9 394 Gene3D G3DSA:3.90.1150.10 271 385 9.5E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS15100 b59a0f132ac97f096b27d8eab7bedfa9 394 SUPERFAMILY SSF53383 1 386 8.54E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS15100 b59a0f132ac97f096b27d8eab7bedfa9 394 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 6.7E-104 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 PIRSF PIRSF005023 1 626 3.7E-218 T 29-03-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 Gene3D G3DSA:3.40.50.2030 407 627 5.6E-77 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 SUPERFAMILY SSF56821 6 630 7.33E-180 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 Gene3D G3DSA:3.40.50.2030 235 401 2.7E-64 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 11 623 5.7E-196 T 29-03-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 Gene3D G3DSA:1.20.1270.30 61 231 7.6E-69 T 29-03-2018 CWR56_RS03465 25a61e4c60a135ca814238cf993113aa 639 Pfam PF03063 Prismane/CO dehydrogenase family 45 608 2.9E-163 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Gene3D G3DSA:1.10.10.60 515 582 1.9E-15 T 29-03-2018 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Gene3D G3DSA:3.10.580.10 5 129 7.2E-24 T 29-03-2018 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 562 582 2.0E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 545 562 2.0E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SMART SM00116 82 129 1.5 T 29-03-2018 IPR000644 CBS domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SMART SM00116 17 65 2.0E-4 T 29-03-2018 IPR000644 CBS domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 297 310 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Pfam PF02954 Bacterial regulatory protein, Fis family 545 579 2.0E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SMART SM00382 293 436 9.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Pfam PF13426 PAS domain 148 240 3.6E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SUPERFAMILY SSF54631 9 128 4.17E-26 T 29-03-2018 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SUPERFAMILY SSF55785 140 233 8.2E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Gene3D G3DSA:1.10.8.60 446 514 4.5E-25 T 29-03-2018 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SUPERFAMILY SSF46689 486 582 5.97E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Pfam PF00158 Sigma-54 interaction domain 273 440 1.2E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 SUPERFAMILY SSF52540 274 516 2.2E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Gene3D G3DSA:3.40.50.300 281 445 7.5E-25 T 29-03-2018 CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Pfam PF00571 CBS domain 10 60 5.0E-10 T 29-03-2018 IPR000644 CBS domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Pfam PF00571 CBS domain 78 128 8.9E-7 T 29-03-2018 IPR000644 CBS domain CWR56_RS16310 d328d30d962ff48ce3b62754063c83e5 586 Gene3D G3DSA:3.30.450.20 137 280 5.5E-11 T 29-03-2018 CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 Gene3D G3DSA:3.40.50.720 1 257 2.1E-51 T 29-03-2018 CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.5E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 Pfam PF00106 short chain dehydrogenase 3 195 3.4E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03730 4b5831168bdf874eb92fd56864809dc3 257 SUPERFAMILY SSF51735 3 257 4.0E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 PRINTS PR00471 Acetate kinase family signature 299 315 6.1E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 PRINTS PR00471 Acetate kinase family signature 7 18 6.1E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 PRINTS PR00471 Acetate kinase family signature 276 289 6.1E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 PRINTS PR00471 Acetate kinase family signature 181 202 6.1E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 SUPERFAMILY SSF53067 5 175 6.14E-73 T 29-03-2018 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 Gene3D G3DSA:3.30.420.40 181 356 7.3E-51 T 29-03-2018 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 Gene3D G3DSA:3.30.420.40 4 180 5.3E-63 T 29-03-2018 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 181 198 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 Hamap MF_00542 Probable butyrate kinase [buk]. 1 359 174.599 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 SUPERFAMILY SSF53067 121 349 2.44E-56 T 29-03-2018 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 Pfam PF00871 Acetokinase family 6 356 1.2E-77 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 6 355 1.0E-176 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS00535 f129adfa74ebc7f5ecb28d7b9507233a 359 PIRSF PIRSF036458 3 358 2.2E-173 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS09350 e9f1d63cb012f2825485bd21a217c6e5 263 Gene3D G3DSA:3.40.50.150 2 263 1.5E-26 T 29-03-2018 CWR56_RS09350 e9f1d63cb012f2825485bd21a217c6e5 263 SUPERFAMILY SSF53335 13 263 6.07E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS09350 e9f1d63cb012f2825485bd21a217c6e5 263 Pfam PF13649 Methyltransferase domain 46 141 5.4E-16 T 29-03-2018 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 SUPERFAMILY SSF56014 118 276 1.7E-40 T 29-03-2018 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 SUPERFAMILY SSF55124 249 386 6.54E-7 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 Gene3D G3DSA:3.30.413.10 371 498 4.1E-19 T 29-03-2018 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 Gene3D G3DSA:3.30.413.10 111 281 4.0E-33 T 29-03-2018 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 SUPERFAMILY SSF56014 376 488 7.72E-21 T 29-03-2018 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 SUPERFAMILY SSF55124 9 115 4.58E-27 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 302 364 3.2E-5 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 42 105 8.8E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 118 269 8.9E-31 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS12275 26c8bdfad77a2d718937cf168b0418b9 515 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 377 486 1.6E-4 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 81 198 1.1E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 591 706 3.4E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 356 5.5E-23 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Gene3D G3DSA:3.40.1110.10 292 512 4.3E-56 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF56784 329 349 3.95E-59 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF56784 474 724 3.95E-59 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Gene3D G3DSA:2.70.150.10 10 222 3.1E-46 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF81665 4 112 9.81E-112 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF81665 222 325 9.81E-112 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF81665 669 875 9.81E-112 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Pfam PF00702 haloacid dehalogenase-like hydrolase 329 634 4.5E-24 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 651 676 1.3E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 592 608 1.3E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 477 495 1.3E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 620 636 1.3E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Pfam PF00122 E1-E2 ATPase 109 311 3.3E-55 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SMART SM00831 1 74 8.0E-18 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 6.8E-39 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 620 639 6.8E-39 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 655 6.8E-39 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 331 345 6.8E-39 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 550 6.8E-39 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 518 529 6.8E-39 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Gene3D G3DSA:1.20.1110.10 513 877 1.6E-82 T 29-03-2018 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 333 339 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 68 1.7E-18 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 Pfam PF00689 Cation transporting ATPase, C-terminus 704 873 6.3E-39 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF81660 340 526 2.55E-51 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS12645 8f3ead1ff80ab7517704dfdf0b082b38 879 SUPERFAMILY SSF81653 112 220 1.24E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 302 317 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Gene3D G3DSA:1.10.460.10 155 352 6.8E-42 T 29-03-2018 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 616 60.272 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 390 406 2.1E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 490 504 2.1E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 2.1E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 2.1E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 308 317 2.1E-26 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Pfam PF01131 DNA topoisomerase 152 561 2.2E-122 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 SMART SM00437 265 527 1.9E-81 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Gene3D G3DSA:1.10.460.10 466 578 3.8E-20 T 29-03-2018 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 SUPERFAMILY SSF56712 3 601 1.44E-174 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Gene3D G3DSA:3.30.65.10 579 624 8.1E-6 T 29-03-2018 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Gene3D G3DSA:3.30.65.10 625 676 0.19 T 29-03-2018 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 SMART SM00436 126 216 1.3E-40 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Gene3D G3DSA:3.40.50.140 3 154 7.5E-41 T 29-03-2018 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Pfam PF01751 Toprim domain 5 133 2.9E-14 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 TIGRFAM TIGR01056 topB: DNA topoisomerase III 4 701 3.0E-240 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 Gene3D G3DSA:2.70.20.10 354 465 2.0E-27 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWR56_RS11270 920db8d575debdf8f7f9cbed5aae818c 706 SMART SM00493 3 126 3.1E-19 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 1.2E-8 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 SUPERFAMILY SSF54211 3 182 4.56E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 SUPERFAMILY SSF52972 250 443 1.13E-65 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 252 442 2.8E-56 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 ProSitePatterns PS01277 Ribonuclease PH signature. 117 129 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Pfam PF01725 Ham1 family 253 441 6.3E-54 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Gene3D G3DSA:3.90.950.10 239 448 8.7E-75 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 SUPERFAMILY SSF55666 154 244 3.14E-22 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 4 237 3.9E-116 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 251 446 48.039 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Gene3D G3DSA:3.30.230.70 5 238 1.6E-52 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Hamap MF_00564 Ribonuclease PH [rph]. 2 238 46.43 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CWR56_RS16635 38031419333dd20e4ab0d634b75dd44e 449 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 5.1E-23 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 SUPERFAMILY SSF110324 10 91 4.53E-34 T 29-03-2018 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 2.5E-40 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 2.5E-40 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 2.5E-40 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 10 89 6.4E-41 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 Gene3D G3DSA:2.40.50.100 28 92 1.2E-32 T 29-03-2018 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 28.617 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 75 1.0E-12 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 Pfam PF01016 Ribosomal L27 protein 10 89 8.1E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05285 a7e71bc6ea96ef4126bd041cae4e50cf 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS03725 0671d55b5c84ab1f66a1fd421d406521 121 Gene3D G3DSA:2.40.33.40 3 118 4.3E-37 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS03725 0671d55b5c84ab1f66a1fd421d406521 121 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 115 1.1E-37 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS03725 0671d55b5c84ab1f66a1fd421d406521 121 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 7 117 5.0E-19 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS03725 0671d55b5c84ab1f66a1fd421d406521 121 SUPERFAMILY SSF141530 4 119 7.06E-37 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:2.60.40.10 518 597 0.029 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:1.10.1330.10 176 241 2.0E-7 T 29-03-2018 CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 SUPERFAMILY SSF49785 774 894 1.53E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 SMART SM01276 998 1372 3.6E-60 T 29-03-2018 IPR031161 Peptidase family M60 domain CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:2.60.120.260 1591 1799 2.0E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 SUPERFAMILY SSF63446 179 231 1.44E-8 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:2.60.120.260 248 499 0.36 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 SUPERFAMILY SSF49785 1666 1793 2.48E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:2.60.120.260 758 904 1.5E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:1.10.238.10 1209 1527 0.093 T 29-03-2018 CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 SUPERFAMILY SSF49265 630 727 3.57E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 ProSitePatterns PS00018 EF-hand calcium-binding domain. 183 195 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 1292 1439 2.7E-17 T 29-03-2018 IPR031161 Peptidase family M60 domain CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 SMART SM00060 632 710 2.2E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1217 1229 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 Gene3D G3DSA:2.60.40.10 623 729 1.6E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS14190 718227b68bbbb09210f8749b9fac77f1 1987 ProSitePatterns PS00018 EF-hand calcium-binding domain. 210 222 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 4.5E-10 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 4.5E-10 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 29 1.5E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 SUPERFAMILY SSF54523 10 96 2.04E-20 T 29-03-2018 CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 1.5E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17520 7cfbd7141c1f9cfee428de6076ceb9b9 173 Gene3D G3DSA:3.30.700.10 10 172 2.6E-22 T 29-03-2018 CWR56_RS18965 d02376b077ccf2c592fc5126f8075ce1 161 Pfam PF02542 YgbB family 1 154 3.6E-69 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CWR56_RS18965 d02376b077ccf2c592fc5126f8075ce1 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CWR56_RS18965 d02376b077ccf2c592fc5126f8075ce1 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.532 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CWR56_RS18965 d02376b077ccf2c592fc5126f8075ce1 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 1.8E-71 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CWR56_RS18965 d02376b077ccf2c592fc5126f8075ce1 161 Gene3D G3DSA:3.30.1330.50 1 158 1.5E-73 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CWR56_RS18965 d02376b077ccf2c592fc5126f8075ce1 161 SUPERFAMILY SSF69765 1 156 7.72E-67 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 1.8E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 361 1.8E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 336 1.8E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 SMART SM00388 158 225 2.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 SMART SM00387 271 382 7.6E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 Gene3D G3DSA:3.30.565.10 232 382 2.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 Gene3D G3DSA:1.10.287.130 148 221 3.7E-15 T 29-03-2018 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 SUPERFAMILY SSF55874 214 380 2.49E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 379 1.9E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 SUPERFAMILY SSF47384 142 225 9.02E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS17975 e5f9edd4b750217603bbfd72df6a3291 384 Pfam PF00512 His Kinase A (phospho-acceptor) domain 159 224 4.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06775 27d7410b14fccff569b3415d3f855b10 288 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 16 221 1.1E-55 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS06775 27d7410b14fccff569b3415d3f855b10 288 PIRSF PIRSF006483 1 288 6.8E-90 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS06775 27d7410b14fccff569b3415d3f855b10 288 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 3.3E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CWR56_RS04215 2d2484650692c84b3c1cdda31f9f8104 314 SUPERFAMILY SSF52540 6 253 1.94E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04215 2d2484650692c84b3c1cdda31f9f8104 314 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 265 6.0E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS04215 2d2484650692c84b3c1cdda31f9f8104 314 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04215 2d2484650692c84b3c1cdda31f9f8104 314 Pfam PF00005 ABC transporter 28 182 4.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04215 2d2484650692c84b3c1cdda31f9f8104 314 SMART SM00382 36 231 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04215 2d2484650692c84b3c1cdda31f9f8104 314 Gene3D G3DSA:3.40.50.300 3 310 9.3E-71 T 29-03-2018 CWR56_RS03595 9f73946fc0de07449979e2b78d9b73ab 371 Pfam PF04346 Ethanolamine utilisation protein, EutH 4 352 6.3E-141 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CWR56_RS03595 9f73946fc0de07449979e2b78d9b73ab 371 PIRSF PIRSF019466 1 370 3.0E-131 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CWR56_RS15735 10e7b3bbda584722a698c6aca006fa78 81 Pfam PF04397 LytTr DNA-binding domain 3 72 3.4E-15 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS15735 10e7b3bbda584722a698c6aca006fa78 81 Gene3D G3DSA:2.20.25.10 38 72 3.8E-5 T 29-03-2018 CWR56_RS15735 10e7b3bbda584722a698c6aca006fa78 81 SMART SM00850 1 73 4.9E-5 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS15735 10e7b3bbda584722a698c6aca006fa78 81 Gene3D G3DSA:2.40.50.40 1 37 2.4E-7 T 29-03-2018 CWR56_RS01520 1f4f3b738695745a19980751c8b3ebfe 357 Gene3D G3DSA:3.30.70.20 166 205 2.5E-10 T 29-03-2018 CWR56_RS01520 1f4f3b738695745a19980751c8b3ebfe 357 Pfam PF04015 Domain of unknown function (DUF362) 43 315 1.9E-46 T 29-03-2018 IPR007160 Domain of unknown function DUF362 CWR56_RS01520 1f4f3b738695745a19980751c8b3ebfe 357 Pfam PF12838 4Fe-4S dicluster domain 196 240 1.0E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS01520 1f4f3b738695745a19980751c8b3ebfe 357 SUPERFAMILY SSF54862 141 297 1.31E-27 T 29-03-2018 CWR56_RS01520 1f4f3b738695745a19980751c8b3ebfe 357 Gene3D G3DSA:3.30.70.20 231 320 3.0E-6 T 29-03-2018 CWR56_RS01520 1f4f3b738695745a19980751c8b3ebfe 357 Gene3D G3DSA:3.30.70.20 206 230 4.5E-15 T 29-03-2018 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 Pfam PF07690 Major Facilitator Superfamily 21 410 3.5E-62 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 Gene3D G3DSA:1.20.1250.20 9 203 1.1E-33 T 29-03-2018 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 4.5E-14 T 29-03-2018 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 4.5E-14 T 29-03-2018 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 4.5E-14 T 29-03-2018 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 338 358 4.5E-14 T 29-03-2018 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 SUPERFAMILY SSF103473 249 468 1.7E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 SUPERFAMILY SSF103473 9 199 1.7E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 425 9.8E-82 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR56_RS09645 bc35f9679fe250e0041ba29d0f0f7af2 475 Gene3D G3DSA:1.20.1250.20 253 475 8.1E-30 T 29-03-2018 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 Pfam PF00005 ABC transporter 348 497 3.4E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 SUPERFAMILY SSF90123 3 314 3.92E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 Gene3D G3DSA:3.40.50.300 315 566 3.2E-76 T 29-03-2018 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 Gene3D G3DSA:1.20.1560.10 2 314 5.1E-56 T 29-03-2018 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 SMART SM00382 357 549 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 Pfam PF00664 ABC transporter transmembrane region 19 287 1.7E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS05015 ca5272b708406c5068ece781e528ae04 566 SUPERFAMILY SSF52540 321 565 1.81E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00155 a24f367f8347482b057f47b4aef5004a 132 Pfam PF00410 Ribosomal protein S8 5 132 1.3E-53 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00155 a24f367f8347482b057f47b4aef5004a 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00155 a24f367f8347482b057f47b4aef5004a 132 Gene3D G3DSA:3.30.1490.10 70 130 1.8E-22 T 29-03-2018 CWR56_RS00155 a24f367f8347482b057f47b4aef5004a 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.687 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00155 a24f367f8347482b057f47b4aef5004a 132 SUPERFAMILY SSF56047 3 132 6.67E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00155 a24f367f8347482b057f47b4aef5004a 132 Gene3D G3DSA:3.30.1370.30 1 67 7.4E-28 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 SUPERFAMILY SSF142019 140 383 1.02E-84 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 SMART SM00928 472 517 3.4E-25 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 SUPERFAMILY SSF142984 384 467 1.83E-24 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 188 362 7.0E-44 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Gene3D G3DSA:3.40.30.10 32 132 6.7E-26 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 SUPERFAMILY SSF52833 34 125 6.37E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 SUPERFAMILY SSF54862 574 626 2.02E-12 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 26 109 6.5E-7 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 485 496 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Pfam PF10531 SLBB domain 388 434 1.7E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Gene3D G3DSA:3.30.70.20 453 585 9.2E-6 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Gene3D G3DSA:3.30.70.20 586 628 3.2E-11 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 473 557 5.1E-33 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 SUPERFAMILY SSF140490 468 570 1.1E-38 T 29-03-2018 CWR56_RS16955 5ceee36f9e8c7d29e49f0849a392c6d7 628 Pfam PF00037 4Fe-4S binding domain 604 625 1.6E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 169 6.3E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 Gene3D G3DSA:3.40.50.1000 1 30 0.025 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 SUPERFAMILY SSF56784 2 219 1.18E-54 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 Gene3D G3DSA:3.40.50.1000 76 224 1.2E-34 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 185 3.8E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 187 6.3E-40 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 Gene3D G3DSA:1.10.150.240 31 75 1.6E-10 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 100 113 8.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 8.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 8.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS14520 63e454a5997bbae30f1d584f4fd52977 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 8.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 5.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 5.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 5.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 5.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 Pfam PF01047 MarR family 28 84 2.8E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 Gene3D G3DSA:1.10.287.100 109 138 0.0024 T 29-03-2018 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 SUPERFAMILY SSF46785 4 131 4.78E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 Gene3D G3DSA:1.10.10.10 12 108 1.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 SMART SM00347 21 121 2.3E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS16115 39a3b842345f0a40dfaa949309d91475 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 60 94 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWR56_RS03680 dbd083fddfa78ca00b3a3d1330a802d6 244 Gene3D G3DSA:3.80.30.10 67 243 1.8E-40 T 29-03-2018 CWR56_RS03680 dbd083fddfa78ca00b3a3d1330a802d6 244 Pfam PF13353 4Fe-4S single cluster domain 15 138 3.1E-21 T 29-03-2018 CWR56_RS03680 dbd083fddfa78ca00b3a3d1330a802d6 244 Pfam PF04055 Radical SAM superfamily 24 176 1.2E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS03680 dbd083fddfa78ca00b3a3d1330a802d6 244 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 235 1.4E-97 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CWR56_RS03680 dbd083fddfa78ca00b3a3d1330a802d6 244 SUPERFAMILY SSF102114 22 214 3.14E-26 T 29-03-2018 CWR56_RS03680 dbd083fddfa78ca00b3a3d1330a802d6 244 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 Pfam PF00990 Diguanylate cyclase, GGDEF domain 314 464 7.9E-14 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 SUPERFAMILY SSF141868 490 737 2.48E-75 T 29-03-2018 IPR001633 EAL domain CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 Pfam PF00563 EAL domain 492 723 5.0E-63 T 29-03-2018 IPR001633 EAL domain CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 311 458 5.9E-12 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 Gene3D G3DSA:3.20.20.450 488 741 5.4E-81 T 29-03-2018 IPR001633 EAL domain CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 Gene3D G3DSA:3.30.70.270 308 487 7.2E-17 T 29-03-2018 CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 Gene3D G3DSA:3.30.450.20 140 269 8.2E-10 T 29-03-2018 CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 SUPERFAMILY SSF55073 320 474 6.67E-15 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 SMART SM00052 483 728 6.0E-83 T 29-03-2018 IPR001633 EAL domain CWR56_RS01020 b6eec4cb922640cbfddd6f41eacceca7 744 SMART SM00267 303 473 7.7E-4 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 SUPERFAMILY SSF52507 1 178 1.96E-63 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 Gene3D G3DSA:3.40.50.1950 1 182 2.6E-59 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 Pfam PF02441 Flavoprotein 5 178 1.8E-49 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 SUPERFAMILY SSF102645 183 398 6.28E-70 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 Gene3D G3DSA:3.40.50.10300 183 399 6.9E-65 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 368 7.5E-69 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWR56_RS13080 1f57a6d91c65c931bffe39c79bc74969 399 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 393 2.8E-144 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 Gene3D G3DSA:3.30.420.40 1 154 9.3E-41 T 29-03-2018 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 SUPERFAMILY SSF53067 145 328 1.69E-46 T 29-03-2018 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 Gene3D G3DSA:3.30.420.40 249 312 1.3E-7 T 29-03-2018 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 331 4.2E-144 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 Pfam PF06723 MreB/Mbl protein 4 330 4.3E-145 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 Gene3D G3DSA:3.30.420.40 155 190 0.0069 T 29-03-2018 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 Gene3D G3DSA:3.90.640.10 191 248 2.4E-29 T 29-03-2018 CWR56_RS00605 a73b3f10adb5fcf5df0b38432a419264 339 SUPERFAMILY SSF53067 4 143 4.27E-42 T 29-03-2018 CWR56_RS07255 891888daeaf7aceadd12098a3dd7580d 255 Pfam PF00005 ABC transporter 24 172 7.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07255 891888daeaf7aceadd12098a3dd7580d 255 Gene3D G3DSA:3.40.50.300 1 241 4.2E-61 T 29-03-2018 CWR56_RS07255 891888daeaf7aceadd12098a3dd7580d 255 SMART SM00382 33 220 8.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07255 891888daeaf7aceadd12098a3dd7580d 255 SUPERFAMILY SSF52540 4 225 7.14E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 SMART SM00448 3 114 1.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 SUPERFAMILY SSF52172 3 130 1.85E-35 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 Gene3D G3DSA:3.40.50.2300 2 133 1.3E-31 T 29-03-2018 CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 236 6.3E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 SUPERFAMILY SSF46894 136 237 2.78E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 Gene3D G3DSA:1.10.10.10 134 241 3.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 SMART SM00862 160 236 3.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS07975 59ece950dff2af4188685d9b1a608d4c 241 Pfam PF00072 Response regulator receiver domain 5 111 4.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 Gene3D G3DSA:3.50.50.60 6 95 1.1E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.5E-20 T 29-03-2018 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 1.5E-20 T 29-03-2018 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 1.5E-20 T 29-03-2018 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.5E-20 T 29-03-2018 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.5E-20 T 29-03-2018 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 SUPERFAMILY SSF51905 237 301 1.19E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 SUPERFAMILY SSF51905 2 157 1.19E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 290 9.2E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 SUPERFAMILY SSF51905 109 237 1.94E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 1.1E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 283 1.1E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 97 105 1.1E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 1.1E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.1E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 Gene3D G3DSA:3.50.50.60 241 310 3.4E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS00870 0be07abcc210e3093c7c14d2e253a44f 408 Gene3D G3DSA:3.50.50.60 96 239 1.2E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 261 5.2E-63 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PRINTS PR00996 Glutamate methyltransferase family signature 27 40 9.5E-38 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PRINTS PR00996 Glutamate methyltransferase family signature 141 157 9.5E-38 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PRINTS PR00996 Glutamate methyltransferase family signature 208 222 9.5E-38 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 9.5E-38 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PRINTS PR00996 Glutamate methyltransferase family signature 105 125 9.5E-38 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PRINTS PR00996 Glutamate methyltransferase family signature 227 250 9.5E-38 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 SMART SM00138 6 267 4.1E-82 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 SUPERFAMILY SSF47757 2 72 3.4E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 Gene3D G3DSA:3.40.50.150 72 267 3.8E-49 T 29-03-2018 CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 PIRSF PIRSF000410 1 267 5.4E-83 T 29-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 58 3.3E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 SUPERFAMILY SSF53335 73 264 1.92E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS02485 a88f443d74ed7ec0bf74a98684a98319 267 Gene3D G3DSA:1.10.155.10 1 70 5.1E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CWR56_RS15525 0fe637f4c59a934b1880458385fe832a 208 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 195 3.5E-41 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 SUPERFAMILY SSF54534 229 332 7.2E-31 T 29-03-2018 CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 Gene3D G3DSA:1.10.4030.10 83 209 1.0E-14 T 29-03-2018 CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 Pfam PF13624 SurA N-terminal domain 49 204 1.1E-8 T 29-03-2018 CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 SUPERFAMILY SSF109998 88 254 2.94E-23 T 29-03-2018 IPR027304 Trigger factor/SurA domain CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 Pfam PF13616 PPIC-type PPIASE domain 218 335 7.7E-32 T 29-03-2018 CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 Gene3D G3DSA:3.10.50.40 219 356 1.9E-39 T 29-03-2018 CWR56_RS11220 085a7ab0442a45c73fecced87708799e 380 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 272 292 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 1.8E-34 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 Gene3D G3DSA:3.40.50.720 165 325 1.5E-35 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 Gene3D G3DSA:3.50.50.60 1 163 3.9E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 SUPERFAMILY SSF51905 1 313 1.94E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 3.6E-33 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 3.6E-33 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 3.6E-33 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 3.6E-33 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.6E-33 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 456 1.9E-165 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 SUPERFAMILY SSF55424 334 456 6.7E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 7.7E-68 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 PIRSF PIRSF000350 1 451 3.3E-92 T 29-03-2018 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 319 8.6E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS03500 0c1da997dc3d7469367a09f61b6145a0 461 Gene3D G3DSA:3.30.390.30 326 453 1.3E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 Gene3D G3DSA:3.90.45.10 1 151 2.5E-51 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 PIRSF PIRSF004749 1 150 1.1E-47 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 Hamap MF_00163 Peptide deformylase [def]. 2 151 26.699 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 SUPERFAMILY SSF56420 2 147 1.26E-50 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 PRINTS PR01576 Peptide deformylase signature 99 117 2.1E-26 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 PRINTS PR01576 Peptide deformylase signature 34 63 2.1E-26 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 PRINTS PR01576 Peptide deformylase signature 118 147 2.1E-26 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 PRINTS PR01576 Peptide deformylase signature 87 98 2.1E-26 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 145 2.4E-44 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS08440 42a2bf2ac061ae1e445f391ab655c349 151 Pfam PF01327 Polypeptide deformylase 4 147 7.7E-44 T 29-03-2018 IPR023635 Peptide deformylase CWR56_RS15320 ac964fd22a503c29ccf52a2fe190b2f4 188 Pfam PF12822 ECF transporter, substrate-specific component 4 166 7.3E-13 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Gene3D G3DSA:3.40.50.300 223 400 1.1E-25 T 29-03-2018 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Gene3D G3DSA:1.10.8.60 401 500 1.4E-23 T 29-03-2018 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 SUPERFAMILY SSF52540 228 469 1.49E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Pfam PF00158 Sigma-54 interaction domain 229 395 6.1E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 SMART SM00382 248 392 3.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Gene3D G3DSA:3.30.450.20 95 217 2.3E-10 T 29-03-2018 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 252 265 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 SUPERFAMILY SSF46689 441 538 2.09E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 SUPERFAMILY SSF55785 100 203 1.92E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 315 330 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Gene3D G3DSA:1.10.10.60 501 542 9.2E-7 T 29-03-2018 CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 105 215 1.3E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Pfam PF13426 PAS domain 114 208 1.6E-5 T 29-03-2018 IPR000014 PAS domain CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 441 450 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS01920 5beb775ff2185ba06e90beadb1536ec3 543 Pfam PF02954 Bacterial regulatory protein, Fis family 503 537 1.7E-4 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 Gene3D G3DSA:2.40.50.140 1 66 5.7E-27 T 29-03-2018 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 PRINTS PR00050 Cold shock protein signature 39 57 2.9E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 PRINTS PR00050 Cold shock protein signature 4 19 2.9E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 PRINTS PR00050 Cold shock protein signature 24 33 2.9E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 PIRSF PIRSF002599 1 66 4.5E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 3.0E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 SUPERFAMILY SSF50249 1 65 1.69E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CWR56_RS11480 57697d0846b68e488e8b673e23c1d94d 66 SMART SM00357 3 66 4.4E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS00765 b5cda677da2498e729b9a1a76d203551 220 SUPERFAMILY SSF52540 3 219 3.66E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00765 b5cda677da2498e729b9a1a76d203551 220 Gene3D G3DSA:3.40.50.300 1 220 5.2E-63 T 29-03-2018 CWR56_RS00765 b5cda677da2498e729b9a1a76d203551 220 SMART SM00382 32 217 7.5E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00765 b5cda677da2498e729b9a1a76d203551 220 Pfam PF00005 ABC transporter 23 168 2.5E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00765 b5cda677da2498e729b9a1a76d203551 220 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SMART SM01231 311 373 9.2E-10 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Gene3D G3DSA:1.10.287.560 311 374 1.6E-13 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SUPERFAMILY SSF55052 163 241 1.02E-11 T 29-03-2018 IPR015162 CheY binding CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 312 373 1.9E-11 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SMART SM00073 1 101 1.1E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Gene3D G3DSA:2.40.50.180 579 645 4.4E-6 T 29-03-2018 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Gene3D G3DSA:1.20.120.160 1 141 5.5E-25 T 29-03-2018 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SUPERFAMILY SSF55874 375 558 3.93E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Gene3D G3DSA:2.30.30.40 646 697 2.4E-19 T 29-03-2018 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Pfam PF01584 CheW-like domain 565 698 4.0E-19 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SUPERFAMILY SSF50341 559 697 9.68E-24 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Pfam PF07194 P2 response regulator binding domain 164 240 4.8E-11 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SMART SM00387 418 560 1.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 421 559 1.1E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SUPERFAMILY SSF47226 2 114 2.24E-21 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SMART SM00260 552 697 4.4E-20 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Pfam PF01627 Hpt domain 3 85 1.2E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Gene3D G3DSA:3.30.70.1110 163 242 5.5E-16 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 Gene3D G3DSA:3.30.565.10 375 568 1.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 538 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 557 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02475 0376c1cb5ed361c4be48eecd2a01bbd2 700 SUPERFAMILY SSF47384 314 374 2.08E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07335 7bb9d9bb8e07d44e249c4e5b13ef03e4 314 Gene3D G3DSA:3.30.930.10 13 314 6.9E-42 T 29-03-2018 CWR56_RS07335 7bb9d9bb8e07d44e249c4e5b13ef03e4 314 PIRSF PIRSF001549 12 314 1.5E-39 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CWR56_RS07335 7bb9d9bb8e07d44e249c4e5b13ef03e4 314 SUPERFAMILY SSF55681 14 309 1.49E-37 T 29-03-2018 CWR56_RS07335 7bb9d9bb8e07d44e249c4e5b13ef03e4 314 Pfam PF13393 Histidyl-tRNA synthetase 14 308 1.4E-56 T 29-03-2018 CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 Pfam PF00069 Protein kinase domain 10 263 7.9E-58 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 SUPERFAMILY SSF56112 5 266 3.24E-80 T 29-03-2018 IPR011009 Protein kinase-like domain CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 Gene3D G3DSA:3.30.200.20 2 77 6.0E-23 T 29-03-2018 CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 Gene3D G3DSA:1.10.510.10 78 384 2.8E-56 T 29-03-2018 CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 SMART SM00740 405 473 6.4E-14 T 29-03-2018 IPR005543 PASTA domain CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 SMART SM00740 474 542 1.1E-18 T 29-03-2018 IPR005543 PASTA domain CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 Pfam PF03793 PASTA domain 410 473 1.5E-13 T 29-03-2018 IPR005543 PASTA domain CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 Pfam PF03793 PASTA domain 480 542 5.3E-17 T 29-03-2018 IPR005543 PASTA domain CWR56_RS13035 e0c49e3b990115f3c5f7ac0dab5c6de5 671 SMART SM00220 10 270 1.9E-70 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWR56_RS14565 cffc7e2be93770d5edcaf0773ed38810 449 Gene3D G3DSA:3.30.2290.10 1 215 2.1E-26 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CWR56_RS14565 cffc7e2be93770d5edcaf0773ed38810 449 SUPERFAMILY SSF111283 3 447 3.66E-105 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CWR56_RS14565 cffc7e2be93770d5edcaf0773ed38810 449 Pfam PF01523 Putative modulator of DNA gyrase 21 308 2.0E-47 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 SMART SM01092 165 257 1.6E-5 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 Gene3D G3DSA:3.30.465.10 53 160 1.9E-11 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 Gene3D G3DSA:3.30.390.50 164 262 6.5E-11 T 29-03-2018 CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 160 1.6E-17 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 SUPERFAMILY SSF55447 170 259 3.4E-9 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 SUPERFAMILY SSF56176 6 160 2.51E-23 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS09980 1c67d1352ddc666ba8583d46d01afaa5 264 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 256 2.4E-6 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 Gene3D G3DSA:2.20.25.10 218 255 5.6E-15 T 29-03-2018 CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 SMART SM00850 157 255 2.2E-34 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 Pfam PF04397 LytTr DNA-binding domain 157 254 1.2E-28 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 SMART SM00448 1 112 1.8E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 Gene3D G3DSA:3.40.50.2300 1 132 3.8E-26 T 29-03-2018 CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 SUPERFAMILY SSF52172 1 117 3.42E-28 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 Gene3D G3DSA:2.40.50.40 147 216 8.0E-19 T 29-03-2018 CWR56_RS13155 803fe21ec235b89a9d6c93a8621a7537 256 Pfam PF00072 Response regulator receiver domain 4 112 6.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08035 97c55ad6a3e1c980bf8603c79bb8f012 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS08035 97c55ad6a3e1c980bf8603c79bb8f012 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS08035 97c55ad6a3e1c980bf8603c79bb8f012 209 Gene3D G3DSA:1.10.260.40 40 100 3.0E-7 T 29-03-2018 CWR56_RS08035 97c55ad6a3e1c980bf8603c79bb8f012 209 SUPERFAMILY SSF46689 5 81 4.74E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08035 97c55ad6a3e1c980bf8603c79bb8f012 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 9.1E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS08035 97c55ad6a3e1c980bf8603c79bb8f012 209 Gene3D G3DSA:1.10.10.60 1 39 6.2E-10 T 29-03-2018 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 41.909 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 4.0E-96 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 SUPERFAMILY SSF52096 10 193 2.86E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 1.5E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 1.5E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 1.5E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 1.5E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 1.5E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 Gene3D G3DSA:3.90.226.10 2 194 6.9E-42 T 29-03-2018 CWR56_RS16780 4f598f367b946d99f8221b996e6e723e 194 Pfam PF00574 Clp protease 13 192 2.6E-82 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CWR56_RS11710 0f6b30a8473c4420ff0da17ee115988f 564 Pfam PF01432 Peptidase family M3 310 541 2.0E-19 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWR56_RS11710 0f6b30a8473c4420ff0da17ee115988f 564 Gene3D G3DSA:1.10.1370.10 68 535 5.0E-53 T 29-03-2018 CWR56_RS11710 0f6b30a8473c4420ff0da17ee115988f 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 14 559 5.8E-189 T 29-03-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related CWR56_RS11710 0f6b30a8473c4420ff0da17ee115988f 564 SUPERFAMILY SSF55486 33 561 1.03E-111 T 29-03-2018 CWR56_RS10915 2b4ec11f470b08a69ded9e3884dced34 139 Gene3D G3DSA:1.10.10.10 77 139 3.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10915 2b4ec11f470b08a69ded9e3884dced34 139 SUPERFAMILY SSF88659 81 137 2.99E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS10915 2b4ec11f470b08a69ded9e3884dced34 139 Pfam PF08281 Sigma-70, region 4 79 131 9.4E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 243 363 1.3E-29 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 239 2.0E-26 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 1.5E-27 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 363 1.5E-93 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 Gene3D G3DSA:3.10.150.10 1 121 5.2E-23 T 29-03-2018 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 SUPERFAMILY SSF55979 244 364 2.88E-33 T 29-03-2018 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 SUPERFAMILY SSF55979 2 116 1.34E-22 T 29-03-2018 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 Gene3D G3DSA:3.10.150.10 247 365 6.7E-28 T 29-03-2018 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 Gene3D G3DSA:3.10.150.10 122 246 2.8E-29 T 29-03-2018 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 PIRSF PIRSF000804 1 365 2.3E-106 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 SMART SM00480 17 360 1.4E-105 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS18445 9e836fa5e42d68d1c9a1c0af268e2d7c 368 SUPERFAMILY SSF55979 128 242 1.05E-24 T 29-03-2018 CWR56_RS13460 7b5ed01b481b0d147cae55d29e200100 428 Pfam PF00675 Insulinase (Peptidase family M16) 61 176 1.9E-15 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CWR56_RS13460 7b5ed01b481b0d147cae55d29e200100 428 SUPERFAMILY SSF63411 12 220 2.93E-40 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS13460 7b5ed01b481b0d147cae55d29e200100 428 SUPERFAMILY SSF63411 278 425 7.97E-19 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS13460 7b5ed01b481b0d147cae55d29e200100 428 Pfam PF05193 Peptidase M16 inactive domain 182 362 1.8E-18 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CWR56_RS13460 7b5ed01b481b0d147cae55d29e200100 428 Gene3D G3DSA:3.30.830.10 2 219 4.1E-45 T 29-03-2018 CWR56_RS13460 7b5ed01b481b0d147cae55d29e200100 428 Gene3D G3DSA:3.30.830.10 220 428 2.6E-23 T 29-03-2018 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 Pfam PF12833 Helix-turn-helix domain 200 278 1.4E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 Pfam PF02311 AraC-like ligand binding domain 28 77 1.6E-7 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 SUPERFAMILY SSF46689 181 228 1.43E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 SUPERFAMILY SSF46689 230 279 1.08E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 Gene3D G3DSA:1.10.10.60 232 280 4.1E-7 T 29-03-2018 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 SUPERFAMILY SSF51182 27 89 2.55E-11 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 SMART SM00342 194 277 5.2E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS18880 7b36eae1be9a77e2db93892bd71b8443 281 Gene3D G3DSA:2.60.120.10 18 231 1.6E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS09520 6bb6d5d13bc908d4ac9f7efa26301173 281 Gene3D G3DSA:1.20.58.280 154 214 0.016 T 29-03-2018 CWR56_RS09520 6bb6d5d13bc908d4ac9f7efa26301173 281 Gene3D G3DSA:1.25.40.10 215 281 3.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS09520 6bb6d5d13bc908d4ac9f7efa26301173 281 Gene3D G3DSA:3.10.450.100 25 143 2.6E-7 T 29-03-2018 CWR56_RS09520 6bb6d5d13bc908d4ac9f7efa26301173 281 SUPERFAMILY SSF48452 166 280 1.44E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 SUPERFAMILY SSF53920 190 462 3.66E-69 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Pfam PF00037 4Fe-4S binding domain 186 207 6.7E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Pfam PF00037 4Fe-4S binding domain 138 160 1.8E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 TIGRFAM TIGR04105 FeFe_hydrog_B1: [FeFe] hydrogenase, group B1/B3 4 460 3.3E-181 T 29-03-2018 IPR027631 [FeFe] hydrogenase, group B1/B3 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 SUPERFAMILY SSF54862 125 210 4.19E-18 T 29-03-2018 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Gene3D G3DSA:1.10.1060.10 146 179 0.038 T 29-03-2018 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Gene3D G3DSA:3.40.50.1780 180 294 1.4E-20 T 29-03-2018 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Gene3D G3DSA:3.40.50.1780 295 406 8.3E-24 T 29-03-2018 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Gene3D G3DSA:3.30.70.20 53 122 0.13 T 29-03-2018 CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 224 457 9.7E-61 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CWR56_RS04395 c554701190e2164a47892a5d98b2cc7c 498 Gene3D G3DSA:3.30.70.20 123 145 1.3E-6 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Gene3D G3DSA:1.20.120.430 125 286 3.9E-31 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 459 35.295 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Pfam PF12631 MnmE helical domain 128 456 9.4E-62 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 376 1.2E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Pfam PF01926 50S ribosome-binding GTPase 224 336 2.7E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 SUPERFAMILY SSF116878 126 225 5.75E-51 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 SUPERFAMILY SSF116878 384 459 5.75E-51 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Gene3D G3DSA:3.30.1360.120 3 124 1.7E-45 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 459 4.3E-132 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 3.2E-6 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 3.2E-6 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 3.2E-6 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 PRINTS PR00449 Transforming protein P21 ras signature 357 379 3.2E-6 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Gene3D G3DSA:1.20.120.430 287 459 7.3E-37 T 29-03-2018 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 125 1.5E-40 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 SUPERFAMILY SSF52540 78 157 2.66E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18410 c398e815ef44bc0dca642a357c496130 459 SUPERFAMILY SSF52540 193 375 2.66E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Gene3D G3DSA:1.10.8.60 269 340 3.0E-30 T 29-03-2018 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Pfam PF11638 DnaA N-terminal domain 5 66 2.6E-12 T 29-03-2018 IPR024633 DnaA N-terminal domain CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 397 416 3.5E-53 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 234 261 3.5E-53 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 136 156 3.5E-53 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 200 214 3.5E-53 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 168 182 3.5E-53 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 SMART SM00382 135 263 2.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 SUPERFAMILY SSF48295 334 438 1.8E-34 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Pfam PF00308 Bacterial dnaA protein 103 320 4.3E-105 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 350 416 3.5E-30 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 4 438 33.312 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 ProSitePatterns PS01008 DnaA protein signature. 397 416 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 7 436 3.9E-174 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Gene3D G3DSA:3.40.50.300 100 267 1.4E-23 T 29-03-2018 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 SMART SM00760 347 416 1.2E-38 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 Gene3D G3DSA:1.10.1750.10 341 438 3.5E-34 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWR56_RS18440 d5ed6532ccab8f4413d974956427a2d2 439 SUPERFAMILY SSF52540 102 315 2.8E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04815 3e9e9390a9d48142b968ed81f6e2a7ea 266 SUPERFAMILY SSF111331 15 265 2.22E-61 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWR56_RS04815 3e9e9390a9d48142b968ed81f6e2a7ea 266 Gene3D G3DSA:3.40.50.10330 1 123 3.5E-25 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWR56_RS04815 3e9e9390a9d48142b968ed81f6e2a7ea 266 Gene3D G3DSA:2.60.200.30 124 244 1.1E-28 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWR56_RS04815 3e9e9390a9d48142b968ed81f6e2a7ea 266 Hamap MF_00361 NAD kinase [nadK]. 2 266 23.931 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWR56_RS04815 3e9e9390a9d48142b968ed81f6e2a7ea 266 Pfam PF01513 ATP-NAD kinase 40 251 3.9E-34 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 SMART SM00448 3 113 3.4E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 Pfam PF00072 Response regulator receiver domain 5 113 7.6E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 SUPERFAMILY SSF46894 136 224 3.12E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 Gene3D G3DSA:3.40.50.2300 1 124 1.0E-28 T 29-03-2018 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 SMART SM00862 147 223 3.3E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 4.8E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 Gene3D G3DSA:1.10.10.10 125 226 5.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16420 5b94914d93950a122c75a8b53d6af92d 226 SUPERFAMILY SSF52172 3 160 3.27E-31 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS07735 972b0742ee3bf67fe597e1f309e26a39 268 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 60 186 1.6E-27 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CWR56_RS07735 972b0742ee3bf67fe597e1f309e26a39 268 Gene3D G3DSA:3.30.1380.10 42 184 3.4E-25 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS07735 972b0742ee3bf67fe597e1f309e26a39 268 SUPERFAMILY SSF55166 54 194 5.23E-26 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 Pfam PF03471 Transporter associated domain 342 416 4.1E-22 T 29-03-2018 IPR005170 Transporter-associated domain CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 SMART SM01091 341 417 1.3E-23 T 29-03-2018 IPR005170 Transporter-associated domain CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 Pfam PF00571 CBS domain 214 262 0.0014 T 29-03-2018 IPR000644 CBS domain CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 Pfam PF00571 CBS domain 275 326 0.0023 T 29-03-2018 IPR000644 CBS domain CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 Gene3D G3DSA:3.30.465.10 333 417 7.3E-25 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 Pfam PF01595 Domain of unknown function DUF21 13 191 4.2E-55 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 SUPERFAMILY SSF54631 193 329 6.44E-30 T 29-03-2018 CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 SUPERFAMILY SSF56176 339 416 2.73E-22 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS04790 8a58d7e6bda76fc42997898f99251b9c 417 Gene3D G3DSA:3.10.580.10 185 332 1.2E-29 T 29-03-2018 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 SUPERFAMILY SSF52540 91 372 1.86E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Gene3D G3DSA:1.10.1790.10 774 881 1.4E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 198 213 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 SUPERFAMILY SSF53062 533 653 5.1E-16 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 SUPERFAMILY SSF63520 788 874 2.35E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 SMART SM00382 125 288 4.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 SUPERFAMILY SSF63520 427 524 2.09E-9 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Gene3D G3DSA:3.40.50.300 81 329 7.8E-25 T 29-03-2018 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Pfam PF00158 Sigma-54 interaction domain 102 267 3.2E-47 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Pfam PF00874 PRD domain 791 876 5.2E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Pfam PF00874 PRD domain 438 520 9.8E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Pfam PF03610 PTS system fructose IIA component 535 643 9.8E-9 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 SUPERFAMILY SSF46785 19 62 4.14E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Gene3D G3DSA:1.10.1790.10 401 517 4.8E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Gene3D G3DSA:3.40.50.510 518 668 1.6E-23 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 21 66 3.4E-6 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CWR56_RS04220 7c4712a8dc339d4f7a5b103b79b14fe6 885 Gene3D G3DSA:1.10.10.10 3 66 2.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 Pfam PF00005 ABC transporter 385 534 8.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 SUPERFAMILY SSF52540 359 600 6.57E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 SMART SM00382 394 580 5.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 Gene3D G3DSA:1.20.1560.10 4 344 4.3E-86 T 29-03-2018 CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 Gene3D G3DSA:3.40.50.300 352 607 5.8E-76 T 29-03-2018 CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 SUPERFAMILY SSF90123 27 341 8.37E-81 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS06935 383d011e48a4b7735a7fc13a1a035df5 607 Pfam PF00664 ABC transporter transmembrane region 42 312 7.0E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Pfam PF00330 Aconitase family (aconitate hydratase) 8 407 7.0E-109 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Gene3D G3DSA:3.40.1060.10 147 269 5.3E-40 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Gene3D G3DSA:3.20.19.10 517 641 9.6E-35 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Gene3D G3DSA:3.30.499.10 270 443 5.8E-55 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Gene3D G3DSA:3.30.499.10 1 146 6.3E-40 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Gene3D G3DSA:3.20.19.10 457 516 2.1E-11 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 Pfam PF00694 Aconitase C-terminal domain 520 574 3.6E-22 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 PRINTS PR00415 Aconitase family signature 186 199 2.2E-23 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 PRINTS PR00415 Aconitase family signature 110 123 2.2E-23 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 PRINTS PR00415 Aconitase family signature 200 213 2.2E-23 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 PRINTS PR00415 Aconitase family signature 124 139 2.2E-23 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 PRINTS PR00415 Aconitase family signature 349 362 2.2E-23 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 PRINTS PR00415 Aconitase family signature 90 98 2.2E-23 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 639 2.3E-270 T 29-03-2018 IPR006250 Aconitase, putative CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 SUPERFAMILY SSF52016 441 639 1.67E-50 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR56_RS04080 f4fe8c55248dcc7c2bba3145cf6fc5ed 641 SUPERFAMILY SSF53732 2 429 2.88E-146 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 Gene3D G3DSA:3.40.50.300 4 243 6.4E-31 T 29-03-2018 CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 SUPERFAMILY SSF52540 13 184 2.46E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 14 34 2.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 64 79 2.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 81 99 2.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 Pfam PF01926 50S ribosome-binding GTPase 14 128 1.4E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 6 397 7.1E-178 T 29-03-2018 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF CWR56_RS10380 94123e37dc89fc423d72c11caba3bfb3 402 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 166 6.5E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS11505 a94a2c61b5661e92849d558ec603f5eb 266 SUPERFAMILY SSF102588 50 171 1.44E-6 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR56_RS11505 a94a2c61b5661e92849d558ec603f5eb 266 Gene3D G3DSA:3.40.50.10320 41 248 2.0E-8 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR56_RS11505 a94a2c61b5661e92849d558ec603f5eb 266 Pfam PF02585 GlcNAc-PI de-N-acetylase 50 173 6.2E-8 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CWR56_RS11280 24b75671769edf7f3a26523772f764b0 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 185 8.5E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11280 24b75671769edf7f3a26523772f764b0 215 SUPERFAMILY SSF53639 9 192 1.47E-52 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11280 24b75671769edf7f3a26523772f764b0 215 SMART SM01007 7 185 2.2E-55 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11280 24b75671769edf7f3a26523772f764b0 215 Gene3D G3DSA:3.40.225.10 3 209 2.5E-51 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 SUPERFAMILY SSF47413 5 72 2.11E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 Gene3D G3DSA:1.10.260.40 2 83 1.9E-15 T 29-03-2018 CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 Pfam PF01381 Helix-turn-helix 12 64 1.7E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 SUPERFAMILY SSF51182 59 180 1.56E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 SMART SM00530 11 66 1.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 Gene3D G3DSA:2.60.120.10 84 182 9.9E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS05065 91c0f1fcc58381c7c35514d78f5203c3 183 Pfam PF07883 Cupin domain 121 173 2.6E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 Gene3D G3DSA:1.10.40.50 266 332 1.5E-19 T 29-03-2018 CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 Pfam PF03193 RsgA GTPase 89 264 1.1E-44 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 SUPERFAMILY SSF52540 105 320 3.57E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 68 319 4.2E-50 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 Gene3D G3DSA:3.40.50.300 105 263 1.8E-22 T 29-03-2018 CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 26 327 29.824 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWR56_RS16865 a2735862f922d58423c8bc2ff89b8326 352 Gene3D G3DSA:2.40.50.140 20 91 1.2E-6 T 29-03-2018 CWR56_RS14665 2f081a21cf33c842939efd7d9cac9661 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 421 3.6E-77 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS14665 2f081a21cf33c842939efd7d9cac9661 453 Pfam PF01554 MatE 248 407 1.2E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS14665 2f081a21cf33c842939efd7d9cac9661 453 Pfam PF01554 MatE 22 183 1.8E-29 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS14665 2f081a21cf33c842939efd7d9cac9661 453 PIRSF PIRSF006603 1 448 5.2E-122 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07690 e0610dd6769d029e9570177fa939168d 241 Pfam PF00005 ABC transporter 29 164 2.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07690 e0610dd6769d029e9570177fa939168d 241 Gene3D G3DSA:3.40.50.300 10 240 2.2E-57 T 29-03-2018 CWR56_RS07690 e0610dd6769d029e9570177fa939168d 241 SUPERFAMILY SSF52540 13 226 3.77E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07690 e0610dd6769d029e9570177fa939168d 241 SMART SM00382 38 213 2.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 SMART SM01134 73 237 1.6E-45 T 29-03-2018 CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 Pfam PF00455 DeoR C terminal sensor domain 75 235 3.4E-37 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 SUPERFAMILY SSF46785 4 60 2.47E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 SUPERFAMILY SSF100950 75 236 8.79E-23 T 29-03-2018 CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 Gene3D G3DSA:3.40.50.1360 74 243 2.0E-26 T 29-03-2018 CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 Gene3D G3DSA:1.10.10.10 1 61 1.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 SMART SM00420 6 58 1.8E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS10140 1fe2d2074701c7b971f221c53e45277c 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.9E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS02035 2440ec3023d275b6d49a6ac7eb70939d 355 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 107 6.2E-6 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR56_RS02035 2440ec3023d275b6d49a6ac7eb70939d 355 SUPERFAMILY SSF51735 2 149 3.61E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS02035 2440ec3023d275b6d49a6ac7eb70939d 355 Gene3D G3DSA:3.40.50.720 1 196 6.7E-21 T 29-03-2018 CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 171 232 1.6E-19 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 SUPERFAMILY SSF47781 160 233 5.67E-27 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 Pfam PF12836 Helix-hairpin-helix motif 169 232 1.5E-22 T 29-03-2018 CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 Gene3D G3DSA:1.10.150.310 190 234 1.6E-15 T 29-03-2018 CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 Gene3D G3DSA:3.10.560.10 58 189 4.3E-12 T 29-03-2018 CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 Pfam PF10531 SLBB domain 78 120 1.8E-8 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 SMART SM00278 211 230 20.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS12615 5128c82ef5164d2cb21f35499432f9dc 234 SMART SM00278 181 200 0.0027 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 423 2.2E-42 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 SUPERFAMILY SSF102735 1 130 1.83E-35 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 Gene3D G3DSA:1.10.3120.10 213 398 1.0E-52 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 SUPERFAMILY SSF54534 89 243 1.45E-34 T 29-03-2018 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 Gene3D G3DSA:3.30.70.1050 1 119 1.6E-33 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 1.1E-40 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 PIRSF PIRSF003095 1 428 8.4E-125 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 239 7.0E-14 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 Hamap MF_00303 Trigger factor [tig]. 1 428 22.589 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 TIGRFAM TIGR00115 tig: trigger factor 12 422 7.8E-137 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CWR56_RS16625 1d648db9aaf8c72bf15864829c275f6c 428 SUPERFAMILY SSF109998 250 427 1.29E-43 T 29-03-2018 IPR027304 Trigger factor/SurA domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 SUPERFAMILY SSF55073 93 248 6.51E-26 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 84 236 9.5E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 Pfam PF00990 Diguanylate cyclase, GGDEF domain 112 237 2.4E-23 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 Gene3D G3DSA:3.30.70.270 82 252 5.9E-31 T 29-03-2018 CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 Pfam PF00563 EAL domain 266 497 2.0E-66 T 29-03-2018 IPR001633 EAL domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 Gene3D G3DSA:3.20.20.450 253 506 2.8E-90 T 29-03-2018 IPR001633 EAL domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 SMART SM00267 77 246 2.2E-16 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 SUPERFAMILY SSF141868 262 510 2.48E-84 T 29-03-2018 IPR001633 EAL domain CWR56_RS07680 d890a7a55d252842ddffeec28fb3c2c0 514 SMART SM00052 256 502 1.9E-90 T 29-03-2018 IPR001633 EAL domain CWR56_RS11540 1c0265dde931808b7dde0d47de3d7444 270 SUPERFAMILY SSF52518 3 266 1.24E-93 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS11540 1c0265dde931808b7dde0d47de3d7444 270 Gene3D G3DSA:3.40.50.970 1 268 1.2E-84 T 29-03-2018 CWR56_RS11540 1c0265dde931808b7dde0d47de3d7444 270 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS11540 1c0265dde931808b7dde0d47de3d7444 270 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 262 5.6E-63 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 SMART SM00388 233 300 7.9E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 SMART SM00304 173 225 1.8E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 Gene3D G3DSA:3.30.565.10 308 440 4.6E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 SUPERFAMILY SSF158472 179 222 2.62E-5 T 29-03-2018 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 Gene3D G3DSA:1.10.287.130 216 294 2.6E-10 T 29-03-2018 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 291 1.7E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 SUPERFAMILY SSF47384 218 293 5.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 Pfam PF14501 GHKL domain 352 436 6.2E-5 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS13795 1fd621af12a66875cb0b0449dcf5db09 440 SUPERFAMILY SSF55874 306 436 7.73E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04310 0afd1ffbd7bdf8ee4d2a0b36cd314ef7 251 SUPERFAMILY SSF52540 1 230 1.46E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04310 0afd1ffbd7bdf8ee4d2a0b36cd314ef7 251 SMART SM00382 31 234 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04310 0afd1ffbd7bdf8ee4d2a0b36cd314ef7 251 Gene3D G3DSA:3.40.50.300 1 248 1.7E-53 T 29-03-2018 CWR56_RS04310 0afd1ffbd7bdf8ee4d2a0b36cd314ef7 251 Pfam PF00005 ABC transporter 23 176 2.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 30 45 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 102 7.7E-45 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 4 103 27.363 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 Pfam PF00338 Ribosomal protein S10p/S20e 8 102 1.4E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 Gene3D G3DSA:3.30.70.600 5 103 6.3E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 PRINTS PR00971 Ribosomal protein S10 family signature 6 19 2.6E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 PRINTS PR00971 Ribosomal protein S10 family signature 62 76 2.6E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 PRINTS PR00971 Ribosomal protein S10 family signature 41 56 2.6E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 SUPERFAMILY SSF54999 6 103 7.98E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CWR56_RS00080 3c6d2a4c9065b3a6f8a7f4f537526751 103 SMART SM01403 8 102 3.2E-58 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 Gene3D G3DSA:3.30.465.10 51 160 1.0E-11 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 SUPERFAMILY SSF56176 6 160 1.25E-22 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 171 256 1.2E-6 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 160 6.5E-18 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 SUPERFAMILY SSF55447 165 260 5.89E-10 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 SMART SM01092 165 257 6.5E-6 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS09945 125384629a08f6731ceefaa95bbbbb07 264 Gene3D G3DSA:3.30.390.50 163 262 3.4E-11 T 29-03-2018 CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 Gene3D G3DSA:2.40.50.40 126 195 5.9E-20 T 29-03-2018 CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 Gene3D G3DSA:3.40.50.2300 1 124 4.2E-18 T 29-03-2018 CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 Pfam PF04397 LytTr DNA-binding domain 139 224 1.1E-19 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 Pfam PF00072 Response regulator receiver domain 4 115 5.7E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 SUPERFAMILY SSF52172 3 123 4.27E-17 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 SMART SM00448 2 115 2.4E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08355 502b2380e9c5cbc8936a8c42241ce757 235 SMART SM00850 136 227 1.0E-23 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 Pfam PF07687 Peptidase dimerisation domain 189 279 2.2E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 SUPERFAMILY SSF53187 301 392 1.2E-75 T 29-03-2018 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 SUPERFAMILY SSF53187 2 200 1.2E-75 T 29-03-2018 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 SUPERFAMILY SSF55031 186 299 1.96E-27 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 Gene3D G3DSA:3.40.630.10 1 265 2.4E-58 T 29-03-2018 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 PIRSF PIRSF005962 1 393 2.1E-112 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 Gene3D G3DSA:3.40.630.10 266 396 3.1E-19 T 29-03-2018 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 Pfam PF01546 Peptidase family M20/M25/M40 72 386 1.8E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS15545 d0d2b068d47b28c30380d35ff43c6f44 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 377 2.6E-94 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 SUPERFAMILY SSF55781 71 248 5.69E-36 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 Gene3D G3DSA:1.10.10.10 3 96 1.0E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 Pfam PF01614 Bacterial transcriptional regulator 126 245 4.6E-19 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 Gene3D G3DSA:3.30.450.40 97 255 1.1E-29 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 SMART SM00346 10 96 0.0035 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 Pfam PF09339 IclR helix-turn-helix domain 10 56 8.1E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CWR56_RS14985 9ea4999fc1bdfc4f384ee189e226a843 258 SUPERFAMILY SSF46785 10 79 2.03E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 PIRSF PIRSF036497 1 313 2.1E-82 T 29-03-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 Gene3D G3DSA:3.40.50.720 1 146 7.3E-31 T 29-03-2018 CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 Gene3D G3DSA:3.30.360.10 147 287 1.9E-40 T 29-03-2018 CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 SUPERFAMILY SSF55347 126 291 6.54E-42 T 29-03-2018 CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 Pfam PF00742 Homoserine dehydrogenase 126 304 1.9E-51 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 118 2.4E-20 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 SUPERFAMILY SSF51735 1 147 2.15E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS05300 26a1bcae5f235485c92a7174877a2cae 401 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 172 194 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 3 310 2.2E-79 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 Pfam PF01895 PhoU domain 345 429 1.4E-17 T 29-03-2018 IPR026022 PhoU domain CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 Pfam PF01895 PhoU domain 451 533 6.5E-14 T 29-03-2018 IPR026022 PhoU domain CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 SUPERFAMILY SSF109755 325 537 5.65E-52 T 29-03-2018 CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 Pfam PF02690 Na+/Pi-cotransporter 13 148 1.7E-53 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 Pfam PF02690 Na+/Pi-cotransporter 160 256 3.7E-18 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 Gene3D G3DSA:1.20.58.220 327 445 9.5E-23 T 29-03-2018 CWR56_RS16525 8aaf60cdfa129606ecf92f588835e47f 542 Gene3D G3DSA:1.20.58.220 446 542 3.5E-21 T 29-03-2018 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Pfam PF09334 tRNA synthetases class I (M) 6 361 1.3E-111 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 SUPERFAMILY SSF47323 351 559 4.3E-43 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 527 644 3.6E-41 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Gene3D G3DSA:1.10.730.10 338 513 3.5E-40 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 SUPERFAMILY SSF52374 3 352 9.73E-107 T 29-03-2018 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Pfam PF01588 Putative tRNA binding domain 551 641 6.0E-30 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Gene3D G3DSA:3.40.50.620 1 229 7.1E-58 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Gene3D G3DSA:3.40.50.620 230 337 4.4E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 510 48.039 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Pfam PF08264 Anticodon-binding domain of tRNA 392 490 2.3E-7 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 Gene3D G3DSA:2.40.50.140 537 645 5.6E-34 T 29-03-2018 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 4.2E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 4.2E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 4.2E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 4.2E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 4.2E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 4.2E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 SUPERFAMILY SSF50249 544 643 1.13E-35 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS17650 1633500567a30070d313c550d02ebd50 645 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 489 6.0E-164 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR56_RS06020 3047124474b27d9a49a12cc71b5733b5 132 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 24 114 1.4E-22 T 29-03-2018 IPR014229 Sporulation protein YtfJ CWR56_RS06020 3047124474b27d9a49a12cc71b5733b5 132 PIRSF PIRSF021377 1 132 8.8E-31 T 29-03-2018 IPR014229 Sporulation protein YtfJ CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 Pfam PF00072 Response regulator receiver domain 4 111 2.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 4.2E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 Gene3D G3DSA:1.10.10.10 121 220 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 SUPERFAMILY SSF52172 1 129 2.56E-31 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 SUPERFAMILY SSF46894 117 218 1.59E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 SMART SM00862 144 217 2.9E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 Gene3D G3DSA:3.40.50.2300 1 120 7.5E-28 T 29-03-2018 CWR56_RS02115 ec20ad177aa549c3b5fd79d8d3e5eef6 220 SMART SM00448 2 111 3.3E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Gene3D G3DSA:1.10.287.130 672 731 7.9E-11 T 29-03-2018 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Gene3D G3DSA:3.30.565.10 732 899 2.9E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 SUPERFAMILY SSF52402 251 349 1.57E-5 T 29-03-2018 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Gene3D G3DSA:3.30.450.40 604 671 0.0016 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 22 230 1.5E-92 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Gene3D G3DSA:3.40.50.620 228 371 2.3E-8 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 SMART SM00388 675 743 3.6E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 SUPERFAMILY SSF47384 670 744 2.16E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Pfam PF13493 Domain of unknown function (DUF4118) 409 514 5.1E-27 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 SUPERFAMILY SSF55874 733 897 5.11E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 788 898 4.0E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 SMART SM00387 787 899 7.8E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Gene3D G3DSA:3.40.50.300 21 159 8.2E-23 T 29-03-2018 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 PRINTS PR00344 Bacterial sensor protein C-terminal signature 842 852 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 PRINTS PR00344 Bacterial sensor protein C-terminal signature 824 838 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 PRINTS PR00344 Bacterial sensor protein C-terminal signature 883 896 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 PRINTS PR00344 Bacterial sensor protein C-terminal signature 859 877 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Pfam PF00512 His Kinase A (phospho-acceptor) domain 676 743 4.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08820 6224c677b5b7b21463c8a351a01400d3 900 Gene3D G3DSA:1.20.120.620 405 506 2.2E-21 T 29-03-2018 CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 Gene3D G3DSA:1.10.3720.10 17 272 5.5E-40 T 29-03-2018 CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 Gene3D G3DSA:1.10.3720.10 294 555 6.2E-22 T 29-03-2018 CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 268 1.5E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 372 550 1.6E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 16 558 1.9E-211 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 SUPERFAMILY SSF161098 292 545 2.49E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17595 2bebae67ceb76e67f8675cb09ff1ab50 562 SUPERFAMILY SSF161098 14 265 5.76E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 SMART SM00850 137 228 1.6E-21 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 SUPERFAMILY SSF52172 1 132 1.22E-21 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 SMART SM00448 2 116 1.1E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 Gene3D G3DSA:2.40.50.40 130 197 4.0E-18 T 29-03-2018 CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 Gene3D G3DSA:3.40.50.2300 1 129 1.0E-22 T 29-03-2018 CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 Pfam PF04397 LytTr DNA-binding domain 141 227 8.7E-18 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS16365 a8c735b69d1f3730c442ef8ddcda53a3 236 Pfam PF00072 Response regulator receiver domain 4 110 4.9E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.3E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Gene3D G3DSA:3.30.980.10 65 142 2.9E-24 T 29-03-2018 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Gene3D G3DSA:3.30.930.10 220 529 1.1E-120 T 29-03-2018 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Gene3D G3DSA:3.40.50.800 530 639 2.4E-34 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 SUPERFAMILY SSF52954 527 632 1.07E-35 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 SUPERFAMILY SSF81271 2 61 3.92E-14 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 6.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 518 6.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 6.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 462 490 6.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 532 544 6.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 317 527 3.2E-39 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 2.1E-226 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 SUPERFAMILY SSF55681 242 524 8.36E-96 T 29-03-2018 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 632 35.135 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Pfam PF02824 TGS domain 2 61 4.9E-12 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Gene3D G3DSA:3.30.54.20 143 186 1.1E-20 T 29-03-2018 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Pfam PF03129 Anticodon binding domain 539 628 1.0E-27 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 SMART SM00863 169 218 1.0E-24 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 SUPERFAMILY SSF55186 64 240 3.92E-66 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWR56_RS02650 d9e80d2988156306ff7c54190cd5f713 639 Gene3D G3DSA:3.10.20.30 1 64 2.7E-21 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS12480 56f5ae1b2aec519623dd915121103d02 339 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 41 331 1.9E-64 T 29-03-2018 IPR010897 Sporulation stage II, protein P CWR56_RS12480 56f5ae1b2aec519623dd915121103d02 339 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 136 336 7.3E-50 T 29-03-2018 IPR010897 Sporulation stage II, protein P CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 Gene3D G3DSA:3.20.20.140 68 328 1.8E-22 T 29-03-2018 CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 Gene3D G3DSA:2.30.40.10 329 388 6.7E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 Pfam PF01979 Amidohydrolase family 50 384 4.3E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 Gene3D G3DSA:2.30.40.10 1 67 2.2E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 SUPERFAMILY SSF51556 53 351 2.54E-48 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 SUPERFAMILY SSF51338 350 386 3.15E-26 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS00700 4fa62d0fed784cd66f9977b51cec0c03 388 SUPERFAMILY SSF51338 3 54 3.15E-26 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 Gene3D G3DSA:3.40.630.20 1 213 3.0E-63 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 1.6E-44 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 1.6E-44 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 1.6E-44 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 1.6E-44 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 1.6E-44 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 29-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 Pfam PF01470 Pyroglutamyl peptidase 1 199 7.1E-89 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 212 8.3E-83 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 SUPERFAMILY SSF53182 1 211 8.5E-72 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 PIRSF PIRSF015592 1 211 4.0E-84 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 29-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CWR56_RS08005 f003db7d9866f4604d8f0c2adac80eb1 213 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 199 39.22 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CWR56_RS02250 62f4a72e72487e816c983bdf3949e22f 275 SUPERFAMILY SSF56317 1 264 4.32E-87 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS02250 62f4a72e72487e816c983bdf3949e22f 275 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 149 169 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CWR56_RS02250 62f4a72e72487e816c983bdf3949e22f 275 Gene3D G3DSA:3.60.110.10 1 275 1.2E-91 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS02250 62f4a72e72487e816c983bdf3949e22f 275 Pfam PF00795 Carbon-nitrogen hydrolase 5 255 4.4E-71 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 Pfam PF00512 His Kinase A (phospho-acceptor) domain 178 240 2.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 SMART SM00387 286 393 1.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 SUPERFAMILY SSF55874 231 391 5.63E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 SUPERFAMILY SSF47384 173 241 9.81E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 373 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 351 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 Gene3D G3DSA:3.30.565.10 236 392 2.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 Gene3D G3DSA:1.10.287.130 168 235 5.7E-12 T 29-03-2018 CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 293 390 6.0E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02110 7266beb74688798603a4ab35d52c5797 393 SMART SM00388 177 241 7.8E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 SUPERFAMILY SSF64158 77 303 1.57E-86 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 Gene3D G3DSA:3.40.1450.10 77 298 1.3E-99 T 29-03-2018 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 PIRSF PIRSF001492 1 510 1.3E-212 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 Pfam PF01676 Metalloenzyme superfamily 4 498 4.9E-81 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 293 3.1E-89 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 4 508 8.0E-220 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 SUPERFAMILY SSF53649 3 77 7.25E-77 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 SUPERFAMILY SSF53649 310 508 7.25E-77 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 509 51.461 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15920 793eec186596d11216da071e9c2a202c 510 Gene3D G3DSA:3.40.720.10 299 510 9.0E-40 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 Gene3D G3DSA:3.20.20.450 346 603 1.3E-75 T 29-03-2018 IPR001633 EAL domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 Gene3D G3DSA:3.30.70.270 172 345 1.2E-29 T 29-03-2018 CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 SMART SM00052 347 594 1.3E-71 T 29-03-2018 IPR001633 EAL domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 SUPERFAMILY SSF141868 353 599 9.94E-74 T 29-03-2018 IPR001633 EAL domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 34 112 1.5E-6 T 29-03-2018 IPR029095 NarX-like, N-terminal CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 Pfam PF00990 Diguanylate cyclase, GGDEF domain 179 330 4.3E-23 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 179 324 5.5E-19 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 Pfam PF00563 EAL domain 357 589 1.2E-60 T 29-03-2018 IPR001633 EAL domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 SMART SM00267 167 337 2.9E-16 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS10270 f71793e243bad2e42e58b4989be81b30 603 SUPERFAMILY SSF55073 183 339 2.28E-25 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 SMART SM00342 23 106 1.5E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 Pfam PF14526 Integron-associated effector binding protein 156 288 7.0E-18 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 Gene3D G3DSA:3.20.80.10 120 288 5.2E-28 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 SUPERFAMILY SSF46689 8 57 2.6E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 SMART SM00871 132 289 3.0E-19 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 Pfam PF12833 Helix-turn-helix domain 30 107 1.0E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 60 102 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 SUPERFAMILY SSF55136 133 288 5.06E-15 T 29-03-2018 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 Gene3D G3DSA:1.10.10.60 60 119 1.3E-10 T 29-03-2018 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 SUPERFAMILY SSF46689 59 112 1.16E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16145 f8aafba95df8c55c90b5f4cc53f2af62 289 Gene3D G3DSA:1.10.10.60 2 59 1.8E-12 T 29-03-2018 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 3 85 7.2E-41 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 Pfam PF00312 Ribosomal protein S15 4 84 1.3E-39 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 ProSitePatterns PS00362 Ribosomal protein S15 signature. 35 65 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 SUPERFAMILY SSF47060 3 85 2.15E-36 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 Gene3D G3DSA:1.10.287.10 1 85 8.3E-36 T 29-03-2018 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 6 84 1.0E-27 T 29-03-2018 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 85 22.585 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS06115 11d4521ddb05ebcbc4e8b5d5061334da 85 SMART SM01387 4 84 7.5E-56 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 Gene3D G3DSA:3.30.70.580 1 105 1.0E-31 T 29-03-2018 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 PIRSF PIRSF001430 1 243 2.3E-80 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 Pfam PF01416 tRNA pseudouridine synthase 144 243 1.3E-25 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 Pfam PF01416 tRNA pseudouridine synthase 9 104 1.0E-10 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 243 35.894 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 Gene3D G3DSA:3.30.70.660 106 242 1.3E-36 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 1.5E-64 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS00255 33b86408928912c71c67b65f60033d92 243 SUPERFAMILY SSF55120 1 243 1.73E-80 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 SMART SM00354 1 68 1.8E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 Pfam PF13377 Periplasmic binding protein-like domain 168 328 1.1E-21 T 29-03-2018 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 Gene3D G3DSA:3.40.50.2300 165 331 3.8E-32 T 29-03-2018 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 SUPERFAMILY SSF53822 61 327 4.71E-37 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 SUPERFAMILY SSF47413 3 51 3.75E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 Gene3D G3DSA:3.40.50.2300 108 164 1.9E-8 T 29-03-2018 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 Gene3D G3DSA:1.10.260.40 2 86 2.4E-10 T 29-03-2018 CWR56_RS03890 5a84d47904db9f16df90747fb7211b30 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 50 5.2E-8 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS10345 66ece727bdb7539398067d9ad53a958e 324 SUPERFAMILY SSF56112 18 248 7.02E-39 T 29-03-2018 IPR011009 Protein kinase-like domain CWR56_RS10345 66ece727bdb7539398067d9ad53a958e 324 Gene3D G3DSA:3.30.200.20 19 109 4.1E-8 T 29-03-2018 CWR56_RS10345 66ece727bdb7539398067d9ad53a958e 324 SMART SM00220 17 265 2.2E-10 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWR56_RS10345 66ece727bdb7539398067d9ad53a958e 324 Pfam PF00069 Protein kinase domain 21 248 5.8E-28 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWR56_RS10345 66ece727bdb7539398067d9ad53a958e 324 Gene3D G3DSA:1.10.510.10 110 308 2.4E-27 T 29-03-2018 CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 SUPERFAMILY SSF90123 9 339 8.24E-83 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 Gene3D G3DSA:3.40.50.300 340 595 2.6E-75 T 29-03-2018 CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 SUPERFAMILY SSF52540 343 590 6.85E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 Pfam PF00664 ABC transporter transmembrane region 25 308 8.8E-52 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 Pfam PF00005 ABC transporter 371 519 5.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 SMART SM00382 379 565 3.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14295 1332bbde6e90c4f5a392b6d6d2f07e77 596 Gene3D G3DSA:1.20.1560.10 1 339 1.0E-85 T 29-03-2018 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 3 437 9.0E-162 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 Pfam PF00919 Uncharacterized protein family UPF0004 3 102 1.3E-30 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 SUPERFAMILY SSF102114 127 368 5.23E-63 T 29-03-2018 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 Gene3D G3DSA:2.40.50.140 378 442 1.1E-18 T 29-03-2018 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 Gene3D G3DSA:3.80.30.20 143 377 1.3E-51 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 Pfam PF01938 TRAM domain 375 440 2.7E-6 T 29-03-2018 IPR002792 TRAM domain CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 2 439 69.132 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 149 169 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 SMART SM00729 145 363 2.6E-60 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 437 1.2E-142 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CWR56_RS06165 65ba966e0bc83b831636d3be650cb9bc 444 Pfam PF04055 Radical SAM superfamily 151 321 7.5E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Gene3D G3DSA:3.50.30.10 392 534 7.8E-42 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 304 351 1.4E-9 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 292 2.7E-48 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Gene3D G3DSA:3.30.470.20 244 341 7.7E-23 T 29-03-2018 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 871 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 519 869 1.4E-88 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Gene3D G3DSA:3.20.20.60 535 874 2.1E-114 T 29-03-2018 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 SUPERFAMILY SSF52009 382 509 2.22E-36 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 PIRSF PIRSF000853 2 875 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Gene3D G3DSA:1.20.80.30 119 198 1.7E-36 T 29-03-2018 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 761 779 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 SUPERFAMILY SSF56059 2 379 1.11E-147 T 29-03-2018 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Gene3D G3DSA:3.30.1490.20 3 118 4.4E-33 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Pfam PF00391 PEP-utilising enzyme, mobile domain 422 504 4.1E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 Gene3D G3DSA:1.10.189.10 342 390 7.4E-21 T 29-03-2018 CWR56_RS12165 712c3e1c77cad27b95b9f6629e0e4044 875 SUPERFAMILY SSF51621 517 872 2.11E-128 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 214 1.4E-39 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 Gene3D G3DSA:3.40.50.1860 116 268 1.3E-45 T 29-03-2018 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 254 5.7E-79 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 SUPERFAMILY SSF53681 109 262 4.19E-36 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 Gene3D G3DSA:3.40.50.1860 2 115 2.9E-32 T 29-03-2018 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 SUPERFAMILY SSF53681 5 107 1.5E-37 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17785 be503b062eb01d9aca31601ad33cdaec 268 Hamap MF_00258 Glutamate racemase [murI]. 4 256 37.737 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 SUPERFAMILY SSF46955 2 101 2.42E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 Gene3D G3DSA:3.20.80.10 131 269 5.9E-26 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 Pfam PF13411 MerR HTH family regulatory protein 2 70 1.9E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 SMART SM00422 2 72 8.6E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 Gene3D G3DSA:1.10.1660.10 1 130 3.9E-23 T 29-03-2018 CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 Pfam PF14526 Integron-associated effector binding protein 120 267 1.9E-22 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 SMART SM00871 117 268 4.6E-15 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS11005 f1c37f9bfa605689a20f07d821202616 271 SUPERFAMILY SSF55136 118 267 2.46E-10 T 29-03-2018 CWR56_RS00235 7303e7744eceb406a619f88c2037ee1c 113 SUPERFAMILY SSF64263 3 113 1.24E-47 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00235 7303e7744eceb406a619f88c2037ee1c 113 TIGRFAM TIGR00059 L17: ribosomal protein bL17 4 113 8.3E-48 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00235 7303e7744eceb406a619f88c2037ee1c 113 Gene3D G3DSA:3.90.1030.10 1 113 2.7E-50 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00235 7303e7744eceb406a619f88c2037ee1c 113 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 2 113 29.062 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00235 7303e7744eceb406a619f88c2037ee1c 113 ProSitePatterns PS01167 Ribosomal protein L17 signature. 31 53 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00235 7303e7744eceb406a619f88c2037ee1c 113 Pfam PF01196 Ribosomal protein L17 17 113 7.8E-41 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 PIRSF PIRSF001549 1 420 6.0E-123 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 418 33.681 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 Pfam PF03129 Anticodon binding domain 330 418 2.7E-15 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 Gene3D G3DSA:3.30.930.10 1 324 3.1E-75 T 29-03-2018 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 SUPERFAMILY SSF55681 4 317 6.32E-99 T 29-03-2018 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 Pfam PF13393 Histidyl-tRNA synthetase 8 311 1.7E-44 T 29-03-2018 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 SUPERFAMILY SSF52954 327 420 6.8E-24 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 408 7.2E-156 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CWR56_RS13895 b2646d3e68e014eaa6733a975b8519e4 420 Gene3D G3DSA:3.40.50.800 325 420 3.3E-20 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.7E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 SUPERFAMILY SSF51735 3 257 1.28E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 1.1E-111 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 1.8E-64 T 29-03-2018 CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 Gene3D G3DSA:3.40.50.720 45 258 9.7E-58 T 29-03-2018 CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 Gene3D G3DSA:3.40.50.720 1 44 5.3E-10 T 29-03-2018 CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13550 5692de6a5ee96c50230e9d32e6b7ecd0 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 PIRSF PIRSF000535 1 305 7.7E-84 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 SUPERFAMILY SSF53613 1 285 7.02E-64 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 Gene3D G3DSA:2.20.150.10 9 43 1.5E-16 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 Gene3D G3DSA:3.40.1190.20 44 305 5.4E-39 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 245 258 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 303 1.2E-106 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 303 4.6E-105 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR56_RS11245 b2d3eaabcd2f1e4d76c1af50090c624e 305 Pfam PF00294 pfkB family carbohydrate kinase 9 284 3.2E-53 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 Pfam PF00206 Lyase 6 299 3.2E-72 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 Pfam PF14698 Argininosuccinate lyase C-terminal 362 429 8.6E-23 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 Gene3D G3DSA:1.10.40.30 374 431 1.0E-23 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00149 Fumarate lyase superfamily signature 230 257 6.5E-25 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 6.5E-25 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 6.5E-25 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00149 Fumarate lyase superfamily signature 274 290 6.5E-25 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 Gene3D G3DSA:1.20.200.10 107 373 5.8E-84 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 SUPERFAMILY SSF48557 3 430 9.42E-133 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 5.8E-60 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00145 Argininosuccinate lyase family signature 309 328 5.8E-60 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 5.8E-60 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00145 Argininosuccinate lyase family signature 192 208 5.8E-60 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00145 Argininosuccinate lyase family signature 230 254 5.8E-60 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 PRINTS PR00145 Argininosuccinate lyase family signature 274 290 5.8E-60 T 29-03-2018 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 ProSitePatterns PS00163 Fumarate lyases signature. 274 283 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 437 38.958 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 431 1.1E-177 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS12630 02a4686dc78678aa021183b64c5e34bc 438 Gene3D G3DSA:1.10.275.10 2 106 4.6E-37 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 SUPERFAMILY SSF46785 2 76 8.11E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 Pfam PF02080 TrkA-C domain 135 197 2.1E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 Gene3D G3DSA:1.10.10.10 1 74 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 SMART SM00345 13 72 3.7E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 Gene3D G3DSA:3.30.70.1450 114 199 5.2E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS06460 80b2978383565001687131f09f5b06d0 209 SUPERFAMILY SSF116726 125 197 4.84E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 SMART SM00937 63 177 3.2E-67 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 SUPERFAMILY SSF75620 8 351 8.76E-139 T 29-03-2018 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 352 2.7E-168 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 Pfam PF03462 PCRF domain 9 202 2.4E-76 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 Gene3D G3DSA:1.20.58.410 2 94 4.9E-19 T 29-03-2018 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 354 41.447 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 Gene3D G3DSA:3.30.160.20 208 292 1.3E-29 T 29-03-2018 CWR56_RS17370 ee615f632b9f2f4a4df68a5fccd548c9 354 Pfam PF00472 RF-1 domain 210 319 3.1E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 PIRSF PIRSF001365 1 296 8.3E-67 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 SMART SM01130 1 295 6.1E-85 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 4.6E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 4.6E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 4.6E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 4.6E-16 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 Gene3D G3DSA:3.20.20.70 3 296 2.0E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 Pfam PF00701 Dihydrodipicolinate synthetase family 4 292 1.3E-64 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS14960 579cf11d05dbd1185a015eebc50802b6 297 SUPERFAMILY SSF51569 6 295 2.09E-78 T 29-03-2018 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 Gene3D G3DSA:1.10.540.10 1 120 2.5E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 7.2E-26 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 Gene3D G3DSA:2.40.110.10 121 216 1.5E-37 T 29-03-2018 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 116 2.8E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 Gene3D G3DSA:1.20.140.10 217 377 5.0E-63 T 29-03-2018 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 SUPERFAMILY SSF56645 2 238 4.19E-85 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 2.1E-50 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 SUPERFAMILY SSF47203 225 376 6.44E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 PIRSF PIRSF016578 128 377 3.3E-19 T 29-03-2018 CWR56_RS01905 497e86c789c5a0fd4815c1239bb45aea 377 PIRSF PIRSF016578 4 118 1.5E-7 T 29-03-2018 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 Pfam PF07687 Peptidase dimerisation domain 202 297 7.3E-14 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 PIRSF PIRSF005962 15 405 9.3E-124 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 SUPERFAMILY SSF53187 17 214 2.23E-80 T 29-03-2018 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 SUPERFAMILY SSF53187 316 401 2.23E-80 T 29-03-2018 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 Gene3D G3DSA:3.40.630.10 2 262 6.3E-42 T 29-03-2018 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 Gene3D G3DSA:3.40.630.10 263 404 8.1E-21 T 29-03-2018 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 Pfam PF01546 Peptidase family M20/M25/M40 88 395 2.9E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 30 394 5.1E-108 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS00810 92d3df0d94dfa6d109209e9f19d09f74 406 SUPERFAMILY SSF55031 201 302 1.31E-27 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS10705 a193d78b0334982369a57ecef1f8d3cb 105 Pfam PF01381 Helix-turn-helix 8 62 1.8E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10705 a193d78b0334982369a57ecef1f8d3cb 105 Gene3D G3DSA:1.10.260.40 1 105 5.7E-21 T 29-03-2018 CWR56_RS10705 a193d78b0334982369a57ecef1f8d3cb 105 SMART SM00530 7 62 5.0E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10705 a193d78b0334982369a57ecef1f8d3cb 105 SUPERFAMILY SSF47413 1 66 4.93E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 745 756 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Gene3D G3DSA:3.40.50.970 789 1179 6.7E-116 T 29-03-2018 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Gene3D G3DSA:3.40.50.970 2 258 8.0E-52 T 29-03-2018 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Gene3D G3DSA:4.10.780.10 632 668 1.3E-17 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 PIRSF PIRSF000159 1 1179 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 SUPERFAMILY SSF53323 415 668 5.49E-88 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Gene3D G3DSA:3.30.70.20 669 784 4.8E-29 T 29-03-2018 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 SUPERFAMILY SSF54862 665 834 8.09E-19 T 29-03-2018 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 966 1077 4.9E-9 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 247 7.6E-81 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Pfam PF13484 4Fe-4S double cluster binding domain 688 757 4.2E-8 T 29-03-2018 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1179 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 374 2.8E-15 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 SMART SM00890 622 679 8.3E-30 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Gene3D G3DSA:3.40.50.920 259 415 9.3E-46 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 425 608 1.2E-31 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 SUPERFAMILY SSF52518 791 1178 7.94E-130 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 SUPERFAMILY SSF52518 5 257 4.41E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Gene3D G3DSA:3.40.920.10 416 625 1.1E-64 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 SUPERFAMILY SSF52922 260 410 3.57E-48 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS13570 f1e69ceb0902257690626671a467b5fe 1179 Pfam PF10371 Domain of unknown function 631 678 4.1E-23 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 Gene3D G3DSA:3.40.630.10 260 373 9.0E-13 T 29-03-2018 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 PIRSF PIRSF005962 1 373 1.6E-107 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 Pfam PF01546 Peptidase family M20/M25/M40 71 369 2.0E-23 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 Gene3D G3DSA:3.40.630.10 2 259 2.4E-42 T 29-03-2018 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 Pfam PF07687 Peptidase dimerisation domain 176 266 3.6E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 360 4.2E-75 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 SUPERFAMILY SSF53187 3 187 6.29E-62 T 29-03-2018 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 SUPERFAMILY SSF53187 286 372 6.29E-62 T 29-03-2018 CWR56_RS13650 58dfa594063baf7e94a39c3440378c10 373 SUPERFAMILY SSF55031 174 274 2.62E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.6E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 SMART SM00357 3 66 1.8E-27 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 SUPERFAMILY SSF50249 1 64 5.78E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 Gene3D G3DSA:2.40.50.140 1 66 4.5E-28 T 29-03-2018 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 PIRSF PIRSF002599 1 66 2.2E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 PRINTS PR00050 Cold shock protein signature 4 19 1.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 PRINTS PR00050 Cold shock protein signature 24 33 1.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 PRINTS PR00050 Cold shock protein signature 39 57 1.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS04385 82e7715044b9a509c526c2790f751055 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CWR56_RS02165 c1e16288b52635ad2881e225e46a5b3d 128 Gene3D G3DSA:1.10.4040.10 72 121 1.3E-18 T 29-03-2018 CWR56_RS02165 c1e16288b52635ad2881e225e46a5b3d 128 Gene3D G3DSA:1.10.10.10 8 70 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02165 c1e16288b52635ad2881e225e46a5b3d 128 PIRSF PIRSF019455 1 128 8.6E-40 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS02165 c1e16288b52635ad2881e225e46a5b3d 128 SUPERFAMILY SSF46785 5 122 1.16E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02165 c1e16288b52635ad2881e225e46a5b3d 128 Pfam PF03965 Penicillinase repressor 7 120 5.9E-39 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS06545 768c1f0fd3a41fba1310ae979dfe0ad6 197 Pfam PF12983 Protein of unknown function (DUF3867) 4 197 5.1E-80 T 29-03-2018 IPR024218 Protein of unknown function DUF3867 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 Gene3D G3DSA:3.40.50.1370 1 144 5.3E-53 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 5 300 2.4E-109 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 1.1E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 1.1E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 289 1.1E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 1.1E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 298 2.6E-32 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 4 303 36.271 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 Gene3D G3DSA:3.40.50.1370 145 302 2.3E-50 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 144 1.7E-48 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 221 230 2.1E-37 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 282 296 2.1E-37 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 2.1E-37 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 2.1E-37 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 2.1E-37 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 2.1E-37 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS00915 4bf31bdb697a650ac553c62e8297713d 306 SUPERFAMILY SSF53671 2 302 7.98E-100 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 Gene3D G3DSA:4.10.320.10 49 105 6.3E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 127 347 5.5E-77 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 Pfam PF02817 e3 binding domain 52 84 2.3E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 Pfam PF02817 e3 binding domain 6 41 6.0E-7 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 SUPERFAMILY SSF47005 4 45 4.84E-8 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 Gene3D G3DSA:4.10.320.10 3 48 1.5E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 Gene3D G3DSA:3.30.559.10 106 348 2.9E-82 T 29-03-2018 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 SUPERFAMILY SSF52777 124 347 3.78E-77 T 29-03-2018 CWR56_RS18915 29e1df763a009d564d68b46ebe930086 348 SUPERFAMILY SSF47005 46 87 1.29E-9 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 SUPERFAMILY SSF53927 205 510 3.61E-106 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 Pfam PF02142 MGS-like domain 14 127 4.7E-24 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 510 39.156 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 442 1.4E-103 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 SUPERFAMILY SSF52335 2 191 1.27E-64 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 SMART SM00851 14 128 1.7E-48 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 SMART SM00798 133 444 1.8E-136 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 Gene3D G3DSA:3.40.140.20 361 500 4.1E-44 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 510 2.5E-171 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 Gene3D G3DSA:3.40.50.1380 1 190 3.2E-67 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 PIRSF PIRSF000414 1 510 9.8E-193 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01105 af060dea0784040de76df9c5fe88577a 510 Gene3D G3DSA:3.40.140.20 209 360 2.1E-44 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 SUPERFAMILY SSF47413 2 67 1.07E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 SUPERFAMILY SSF51182 53 181 2.9E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 Gene3D G3DSA:2.60.120.10 64 183 1.5E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 Pfam PF07883 Cupin domain 108 169 9.8E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 SMART SM00530 5 60 5.4E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 Pfam PF01381 Helix-turn-helix 7 57 9.6E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06485 3dc4f7d005b9cd5c3a803f7d27ce1104 188 Gene3D G3DSA:1.10.260.40 1 63 3.3E-15 T 29-03-2018 CWR56_RS11910 c08efea9490d5c5f8199c2d32b3352b2 335 SUPERFAMILY SSF53955 53 157 1.5E-9 T 29-03-2018 IPR023346 Lysozyme-like domain CWR56_RS11910 c08efea9490d5c5f8199c2d32b3352b2 335 Gene3D G3DSA:1.10.530.10 45 206 2.0E-13 T 29-03-2018 CWR56_RS11910 c08efea9490d5c5f8199c2d32b3352b2 335 Gene3D G3DSA:3.90.1720.10 207 335 1.4E-35 T 29-03-2018 CWR56_RS11910 c08efea9490d5c5f8199c2d32b3352b2 335 SUPERFAMILY SSF54001 206 334 3.92E-38 T 29-03-2018 CWR56_RS11910 c08efea9490d5c5f8199c2d32b3352b2 335 Pfam PF00877 NlpC/P60 family 226 331 6.3E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS11910 c08efea9490d5c5f8199c2d32b3352b2 335 Pfam PF13702 Lysozyme-like 48 203 1.2E-58 T 29-03-2018 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 Gene3D G3DSA:3.30.70.1170 168 235 1.4E-17 T 29-03-2018 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 9.1E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 9.1E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 9.1E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 387 9.1E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 9.1E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 SUPERFAMILY SSF48013 3 125 6.8E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 180 438 2.1E-63 T 29-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 SUPERFAMILY SSF53335 136 440 2.27E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 4 439 2.0E-119 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 161 240 6.7E-9 T 29-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 Pfam PF01029 NusB family 2 122 1.2E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 Pfam PF01189 16S rRNA methyltransferase RsmB/F 245 438 3.7E-56 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 Gene3D G3DSA:1.10.940.10 1 143 6.8E-30 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS13050 0684c7cd209fbaa03075ca4274f554e4 441 Gene3D G3DSA:3.40.50.150 236 441 1.4E-53 T 29-03-2018 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SUPERFAMILY SSF52540 58 345 8.69E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 456 7.6E-151 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SUPERFAMILY SSF47819 621 701 1.22E-19 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SUPERFAMILY SSF47819 521 599 1.29E-24 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SMART SM00341 620 700 3.7E-8 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SMART SM00341 520 600 4.3E-18 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SMART SM00490 243 324 2.2E-30 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SMART SM00487 14 211 6.3E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF00270 DEAD/DEAH box helicase 21 181 9.8E-23 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF09382 RQC domain 402 515 5.5E-29 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF00570 HRDC domain 625 689 3.5E-14 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF00570 HRDC domain 524 590 1.7E-18 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Gene3D G3DSA:1.10.150.80 602 700 3.5E-21 T 29-03-2018 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Gene3D G3DSA:1.10.150.80 518 601 4.6E-24 T 29-03-2018 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF00271 Helicase conserved C-terminal domain 216 323 3.8E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF16124 RecQ zinc-binding 336 398 2.0E-12 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Gene3D G3DSA:1.10.10.10 398 517 8.7E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Pfam PF14493 Helix-turn-helix domain 721 812 5.7E-19 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SUPERFAMILY SSF46785 396 546 1.09E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 593 2.9E-232 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Gene3D G3DSA:3.40.50.300 203 397 6.8E-51 T 29-03-2018 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 SMART SM00956 405 515 5.0E-43 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Gene3D G3DSA:1.10.10.60 701 753 8.1E-4 T 29-03-2018 CWR56_RS08135 52db1df57a17c8b44ca71f5c47250bfc 827 Gene3D G3DSA:3.40.50.300 1 201 7.2E-34 T 29-03-2018 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 Gene3D G3DSA:3.20.20.80 2 468 4.2E-155 T 29-03-2018 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 6.4E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 385 396 6.4E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 423 6.4E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 6.4E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 6.4E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 365 373 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 SUPERFAMILY SSF51445 3 465 3.98E-158 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS04005 7ca0a9663145f47173d5f1d4b06c81b9 468 Pfam PF00232 Glycosyl hydrolase family 1 3 465 4.3E-142 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 239 23.959 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 SUPERFAMILY SSF53613 257 523 2.55E-69 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 Gene3D G3DSA:3.40.50.10260 3 246 5.5E-53 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 7 239 8.9E-40 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 259 520 1.7E-57 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 Pfam PF03853 YjeF-related protein N-terminus 27 218 1.1E-36 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 PIRSF PIRSF017184 1 526 3.3E-123 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 Gene3D G3DSA:3.40.1190.20 251 525 3.3E-44 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 254 525 20.072 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 SUPERFAMILY SSF64153 10 111 2.88E-52 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 SUPERFAMILY SSF64153 146 246 2.88E-52 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CWR56_RS04320 079ed0b2305655e723770eb2709d9731 526 Pfam PF01256 Carbohydrate kinase 277 516 4.1E-55 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 SUPERFAMILY SSF53448 81 365 3.16E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 Pfam PF13641 Glycosyltransferase like family 2 80 319 6.3E-28 T 29-03-2018 CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 Gene3D G3DSA:2.40.10.220 507 615 3.2E-10 T 29-03-2018 CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 Gene3D G3DSA:3.90.550.10 79 329 9.7E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 Pfam PF07238 PilZ domain 510 591 2.0E-6 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 PRINTS PR01439 Cellulose synthase subunit A signature 6 26 1.2E-8 T 29-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 PRINTS PR01439 Cellulose synthase subunit A signature 343 369 1.2E-8 T 29-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CWR56_RS12865 921c651a0237ba1e3d610cccda53aaf3 768 PRINTS PR01439 Cellulose synthase subunit A signature 88 107 1.2E-8 T 29-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Gene3D G3DSA:1.25.40.10 223 280 3.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Pfam PF13424 Tetratricopeptide repeat 238 307 2.3E-8 T 29-03-2018 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 155 188 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 75 108 440.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 355 388 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 236 269 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 315 348 34.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 276 309 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 197 230 69.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00028 115 148 0.87 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Gene3D G3DSA:1.10.260.40 1 67 1.6E-13 T 29-03-2018 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Gene3D G3DSA:1.25.40.10 68 167 2.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SUPERFAMILY SSF48452 323 427 3.92E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Pfam PF12844 Helix-turn-helix domain 7 66 8.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SUPERFAMILY SSF47413 5 64 7.04E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Gene3D G3DSA:1.25.40.10 168 222 1.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Pfam PF14938 Soluble NSF attachment protein, SNAP 68 229 3.3E-6 T 29-03-2018 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SUPERFAMILY SSF48452 92 339 7.08E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Gene3D G3DSA:1.25.40.10 332 427 2.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 Gene3D G3DSA:1.25.40.10 281 331 8.5E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS18370 de9e7c85667c83a5aaf6db305dfef059 430 SMART SM00530 9 63 3.0E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 460 477 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 Gene3D G3DSA:3.30.1360.60 445 521 1.2E-23 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 2 521 1.2E-230 T 29-03-2018 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 SUPERFAMILY SSF55604 447 520 5.49E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 406 507 1.5E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 Pfam PF02378 Phosphotransferase system, EIIC 11 344 1.4E-65 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15260 86982c01e5bfdb6716b6af28495c933e 521 Pfam PF00367 phosphotransferase system, EIIB 450 481 3.2E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS04255 d2e3285aed5bdc27799f83f33e752afe 326 Gene3D G3DSA:3.40.50.1820 67 324 4.7E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS04255 d2e3285aed5bdc27799f83f33e752afe 326 SUPERFAMILY SSF53474 63 320 2.81E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS04255 d2e3285aed5bdc27799f83f33e752afe 326 Pfam PF12146 Serine aminopeptidase, S33 97 212 1.5E-11 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CWR56_RS04255 d2e3285aed5bdc27799f83f33e752afe 326 Pfam PF12146 Serine aminopeptidase, S33 253 298 2.6E-7 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 Pfam PF00085 Thioredoxin 3 102 9.0E-30 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 Gene3D G3DSA:3.40.30.10 2 69 1.6E-27 T 29-03-2018 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 SUPERFAMILY SSF52833 3 105 1.61E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 103 8.0E-36 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 PRINTS PR00421 Thioredoxin family signature 21 29 1.2E-7 T 29-03-2018 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 PRINTS PR00421 Thioredoxin family signature 69 80 1.2E-7 T 29-03-2018 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 PRINTS PR00421 Thioredoxin family signature 29 38 1.2E-7 T 29-03-2018 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 PIRSF PIRSF000077 1 105 2.1E-36 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR56_RS08080 46f6ca1a4aef1e7fd0658244235e6c63 105 Gene3D G3DSA:3.40.30.10 70 105 1.7E-4 T 29-03-2018 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 SUPERFAMILY SSF53062 596 713 1.96E-15 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Gene3D G3DSA:1.10.1790.10 462 582 1.6E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Gene3D G3DSA:1.10.10.10 43 108 1.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Gene3D G3DSA:3.40.930.10 839 977 2.8E-27 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 SMART SM00382 152 301 2.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 SUPERFAMILY SSF52540 113 371 9.46E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 844 975 9.0E-29 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Gene3D G3DSA:3.40.50.300 109 458 2.1E-24 T 29-03-2018 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Pfam PF03610 PTS system fructose IIA component 598 710 2.6E-9 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Gene3D G3DSA:3.40.50.510 583 732 1.1E-25 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Pfam PF00158 Sigma-54 interaction domain 129 294 6.8E-44 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 SUPERFAMILY SSF63520 491 584 5.89E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Pfam PF00874 PRD domain 503 584 1.5E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 SUPERFAMILY SSF55804 840 975 3.66E-28 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS18925 18f58ef823e948a9c3b605542101c2e8 982 Gene3D G3DSA:3.40.50.2300 733 832 4.5E-5 T 29-03-2018 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Gene3D G3DSA:3.20.20.60 168 323 7.9E-67 T 29-03-2018 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Gene3D G3DSA:3.20.20.60 2 84 4.0E-19 T 29-03-2018 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 SUPERFAMILY SSF51621 5 79 5.58E-103 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 SUPERFAMILY SSF51621 169 346 5.58E-103 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 SUPERFAMILY SSF52009 467 583 3.27E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 315 331 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 246 270 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 296 314 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 271 295 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 219 245 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 188 202 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 PRINTS PR01050 Pyruvate kinase family signature 63 79 4.7E-82 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Pfam PF00224 Pyruvate kinase, barrel domain 6 344 1.6E-152 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 474 6.7E-194 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 505 576 2.9E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Gene3D G3DSA:2.40.33.10 85 167 6.1E-34 T 29-03-2018 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 SUPERFAMILY SSF50800 74 169 5.06E-30 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Gene3D G3DSA:3.50.30.10 478 585 2.1E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 SUPERFAMILY SSF52935 325 474 2.75E-44 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 472 2.0E-37 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS16895 ac63be53bd880efdd4360a0c8241f684 586 Gene3D G3DSA:3.40.1380.20 324 475 3.3E-57 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Gene3D G3DSA:3.30.70.20 121 142 8.1E-6 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 SUPERFAMILY SSF53920 188 466 2.75E-70 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Gene3D G3DSA:3.30.70.20 193 236 1.5E-6 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Gene3D G3DSA:3.30.70.20 78 120 0.095 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 SUPERFAMILY SSF54862 123 208 3.93E-17 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Gene3D G3DSA:3.30.70.20 168 192 2.8E-11 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Gene3D G3DSA:3.40.50.1780 276 404 1.6E-26 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 222 454 3.4E-63 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 TIGRFAM TIGR04105 FeFe_hydrog_B1: [FeFe] hydrogenase, group B1/B3 4 458 4.5E-184 T 29-03-2018 IPR027631 [FeFe] hydrogenase, group B1/B3 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Gene3D G3DSA:1.10.1060.10 143 167 0.054 T 29-03-2018 CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Pfam PF00037 4Fe-4S binding domain 136 158 3.9E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS04390 9556c0e92207320edb44f01cdffa359e 496 Pfam PF00037 4Fe-4S binding domain 184 205 8.9E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 Gene3D G3DSA:3.40.50.300 15 238 2.2E-92 T 29-03-2018 CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 Gene3D G3DSA:3.40.50.300 239 444 8.5E-75 T 29-03-2018 CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 Pfam PF01268 Formate--tetrahydrofolate ligase 4 558 3.3E-271 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 SUPERFAMILY SSF52540 6 556 4.69E-245 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 Gene3D G3DSA:3.10.410.10 446 534 5.4E-39 T 29-03-2018 CWR56_RS03475 e46f428bb4850661930c7cbe8c2e4dd6 558 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 3 558 49.044 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR56_RS05075 2765aeedac0bb30dc39de7eea0e1b81d 326 Gene3D G3DSA:3.20.20.70 228 321 0.036 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Gene3D G3DSA:3.30.450.20 174 293 7.9E-8 T 29-03-2018 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Pfam PF08447 PAS fold 677 750 7.0E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Gene3D G3DSA:3.30.450.20 369 478 0.007 T 29-03-2018 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Pfam PF00990 Diguanylate cyclase, GGDEF domain 476 632 3.7E-40 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 SMART SM00086 728 771 12.0 T 29-03-2018 IPR001610 PAC motif CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 SMART SM00086 422 464 8.7 T 29-03-2018 IPR001610 PAC motif CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Gene3D G3DSA:3.30.450.20 62 173 2.9E-8 T 29-03-2018 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 474 636 8.4E-44 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Gene3D G3DSA:3.30.450.20 651 776 2.5E-12 T 29-03-2018 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 SUPERFAMILY SSF55073 480 639 5.49E-42 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Gene3D G3DSA:3.30.70.270 479 638 1.2E-46 T 29-03-2018 CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 SMART SM00267 463 637 5.1E-43 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 SUPERFAMILY SSF55785 657 769 3.32E-13 T 29-03-2018 IPR000014 PAS domain CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 672 773 8.4E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS06185 5b670ed8ade7ae4621ef7690b8b549cb 778 Pfam PF02743 Cache domain 40 281 4.9E-13 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:3.30.470.20 119 401 6.2E-63 T 29-03-2018 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1061 12.918 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1050 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:3.30.470.20 743 931 2.0E-36 T 29-03-2018 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:1.10.1030.10 402 534 1.3E-45 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SUPERFAMILY SSF48108 395 549 2.88E-44 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.8E-80 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 869 9.1E-38 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:3.30.1490.20 651 742 2.0E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SUPERFAMILY SSF56059 128 399 2.12E-105 T 29-03-2018 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SUPERFAMILY SSF52335 940 1058 3.14E-31 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:3.40.50.1380 932 1068 7.0E-34 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SUPERFAMILY SSF56059 669 930 1.06E-95 T 29-03-2018 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:3.40.50.20 535 650 1.1E-59 T 29-03-2018 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SMART SM00851 953 1040 4.8E-25 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SMART SM01096 420 543 7.6E-60 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 3.8E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SUPERFAMILY SSF52440 553 671 1.58E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Gene3D G3DSA:3.40.50.20 5 117 2.8E-38 T 29-03-2018 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 SUPERFAMILY SSF52440 1 127 5.32E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1066 13.372 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 543 4.3E-37 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17920 272afa6f3f4c43c73f371aae3545644e 1068 Pfam PF02142 MGS-like domain 954 1035 8.9E-21 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 SMART SM00533 9 315 3.9E-22 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 Gene3D G3DSA:3.40.50.300 292 554 1.4E-35 T 29-03-2018 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 Pfam PF00488 MutS domain V 331 513 3.8E-37 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 PIRSF PIRSF005814 1 792 2.4E-258 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 SUPERFAMILY SSF48334 22 288 3.79E-23 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 Pfam PF01713 Smr domain 717 792 3.6E-18 T 29-03-2018 IPR002625 Smr domain CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 SUPERFAMILY SSF160443 715 792 5.36E-10 T 29-03-2018 IPR002625 Smr domain CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 791 21.207 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 SUPERFAMILY SSF52540 293 513 4.5E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 SMART SM00534 328 513 1.7E-79 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 792 5.8E-224 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS03410 95a85149df28ccfabcd7e1aec00fd05c 792 SMART SM00463 714 792 8.3E-12 T 29-03-2018 IPR002625 Smr domain CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Gene3D G3DSA:3.40.50.2300 363 449 3.7E-12 T 29-03-2018 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Gene3D G3DSA:1.10.10.10 1 57 5.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Gene3D G3DSA:1.10.10.10 79 141 1.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Pfam PF00874 PRD domain 264 353 3.2E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Gene3D G3DSA:3.40.930.10 495 639 2.1E-24 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 SUPERFAMILY SSF46785 2 43 2.33E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12915 eef41e18d45389064c208b448256e139 639 SUPERFAMILY SSF55804 495 637 1.16E-28 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Pfam PF08279 HTH domain 4 45 8.9E-9 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 500 637 1.6E-26 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Gene3D G3DSA:1.10.1790.10 153 248 0.04 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Pfam PF05043 Mga helix-turn-helix domain 84 151 1.4E-9 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS12915 eef41e18d45389064c208b448256e139 639 SUPERFAMILY SSF52794 366 445 5.75E-5 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 SUPERFAMILY SSF63520 238 356 3.79E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12915 eef41e18d45389064c208b448256e139 639 Gene3D G3DSA:1.10.1790.10 254 357 1.6E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11670 8aa54842504b431e9043a6f014ca5394 381 Gene3D G3DSA:3.40.718.10 23 229 2.7E-13 T 29-03-2018 CWR56_RS11670 8aa54842504b431e9043a6f014ca5394 381 Pfam PF02504 Fatty acid synthesis protein 26 359 1.1E-64 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CWR56_RS11670 8aa54842504b431e9043a6f014ca5394 381 SUPERFAMILY SSF53659 26 290 1.15E-26 T 29-03-2018 CWR56_RS11670 8aa54842504b431e9043a6f014ca5394 381 PIRSF PIRSF036593 1 380 4.4E-188 T 29-03-2018 IPR012116 Glycine/sarcosine/betaine reductase complex, protein C, alpha subunit CWR56_RS09165 49532bd06fbaf3857ab8be73f0757d63 199 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS09165 49532bd06fbaf3857ab8be73f0757d63 199 SMART SM00382 34 190 6.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09165 49532bd06fbaf3857ab8be73f0757d63 199 Gene3D G3DSA:3.40.50.300 1 197 7.5E-56 T 29-03-2018 CWR56_RS09165 49532bd06fbaf3857ab8be73f0757d63 199 Pfam PF00005 ABC transporter 25 156 2.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09165 49532bd06fbaf3857ab8be73f0757d63 199 SUPERFAMILY SSF52540 5 194 5.47E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04820 d06806d0c3df3763e2abee4c1bfddf6e 286 Gene3D G3DSA:3.40.50.300 1 247 1.9E-48 T 29-03-2018 CWR56_RS04820 d06806d0c3df3763e2abee4c1bfddf6e 286 SUPERFAMILY SSF52540 3 206 1.25E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04820 d06806d0c3df3763e2abee4c1bfddf6e 286 Pfam PF00005 ABC transporter 16 155 8.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04820 d06806d0c3df3763e2abee4c1bfddf6e 286 SMART SM00382 25 204 5.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01405 ab909f3ad0e4c812462ff34a5556c71a 376 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 368 1.6E-109 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS01405 ab909f3ad0e4c812462ff34a5556c71a 376 Gene3D G3DSA:3.40.50.1970 8 182 7.0E-53 T 29-03-2018 CWR56_RS01405 ab909f3ad0e4c812462ff34a5556c71a 376 SUPERFAMILY SSF56796 2 374 5.63E-113 T 29-03-2018 CWR56_RS01405 ab909f3ad0e4c812462ff34a5556c71a 376 Gene3D G3DSA:1.20.1090.10 183 376 1.6E-47 T 29-03-2018 CWR56_RS14895 273719b03908cd38a23cf931bd69f1ee 323 SUPERFAMILY SSF47240 3 321 2.88E-91 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS14895 273719b03908cd38a23cf931bd69f1ee 323 Gene3D G3DSA:1.10.620.20 3 297 1.7E-73 T 29-03-2018 CWR56_RS14895 273719b03908cd38a23cf931bd69f1ee 323 Pfam PF00268 Ribonucleotide reductase, small chain 12 285 1.3E-83 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14895 273719b03908cd38a23cf931bd69f1ee 323 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 10 322 3.3E-139 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR56_RS14895 273719b03908cd38a23cf931bd69f1ee 323 PIRSF PIRSF000355 1 320 5.4E-97 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS01685 86ce4b06a93c4dad44579c81a4c8202c 301 Pfam PF07728 AAA domain (dynein-related subfamily) 54 186 8.6E-19 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CWR56_RS01685 86ce4b06a93c4dad44579c81a4c8202c 301 SUPERFAMILY SSF52540 44 251 6.08E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01685 86ce4b06a93c4dad44579c81a4c8202c 301 Gene3D G3DSA:3.40.50.300 38 204 1.6E-19 T 29-03-2018 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 Pfam PF00411 Ribosomal protein S11 22 131 1.2E-50 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 PIRSF PIRSF002131 1 132 1.0E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 SUPERFAMILY SSF53137 17 132 2.09E-50 T 29-03-2018 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 13 129 2.4E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 Gene3D G3DSA:3.30.420.80 6 132 1.4E-46 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 132 34.213 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00220 c1ab0a1d7c954eaf1302fe2e3eb41b4a 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 100 122 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 8.9E-83 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 PIRSF PIRSF001259 1 397 4.6E-167 T 29-03-2018 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 396 42.285 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 206 394 7.4E-79 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 SUPERFAMILY SSF55821 2 199 1.01E-82 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 392 52.176 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 SUPERFAMILY SSF142695 203 371 1.96E-65 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 37.14 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 Pfam PF00925 GTP cyclohydrolase II 207 370 4.6E-69 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 5.6E-76 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08120 23bcb02ad936e375d1c248b205aa6879 397 Gene3D G3DSA:3.90.870.10 1 210 1.2E-90 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 276 35.078 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 Gene3D G3DSA:3.10.310.10 129 262 9.2E-37 T 29-03-2018 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 Pfam PF01678 Diaminopimelate epimerase 3 127 1.1E-31 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 Pfam PF01678 Diaminopimelate epimerase 158 268 1.2E-22 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 SUPERFAMILY SSF54506 1 134 3.03E-36 T 29-03-2018 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 SUPERFAMILY SSF54506 144 274 1.95E-38 T 29-03-2018 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 274 1.2E-83 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CWR56_RS13100 ad328337c712e48874249078ab5dc3e7 276 Gene3D G3DSA:3.10.310.10 1 128 3.2E-45 T 29-03-2018 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Pfam PF08275 DNA primase catalytic core, N-terminal domain 131 248 5.3E-39 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Pfam PF13155 Toprim-like 258 342 5.8E-20 T 29-03-2018 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 TIGRFAM TIGR01391 dnaG: DNA primase 5 411 9.6E-141 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Pfam PF10410 DnaB-helicase binding domain of primase 363 417 6.9E-11 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Gene3D G3DSA:3.90.580.10 3 100 3.7E-36 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 SMART SM00400 34 88 2.8E-36 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Hamap MF_00974 DNA primase [dnaG]. 2 580 27.751 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Gene3D G3DSA:3.90.980.10 106 237 2.1E-40 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Gene3D G3DSA:1.20.50.20 363 414 3.6E-6 T 29-03-2018 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 SUPERFAMILY SSF56731 114 416 1.7E-96 T 29-03-2018 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Pfam PF01807 CHC2 zinc finger 6 98 1.6E-37 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 Gene3D G3DSA:3.40.1360.10 238 361 2.9E-31 T 29-03-2018 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 SMART SM00493 255 326 2.2E-16 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 PIRSF PIRSF002811 1 591 4.6E-162 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CWR56_RS06840 b36a125403478b9b11fa3141ecd68681 596 SUPERFAMILY SSF57783 4 96 1.68E-36 T 29-03-2018 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 SUPERFAMILY SSF56104 2 229 7.19E-86 T 29-03-2018 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 228 3.0E-78 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 ProSitePatterns PS01058 SAICAR synthetase signature 2. 169 177 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 Pfam PF01259 SAICAR synthetase 3 228 1.9E-69 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 Gene3D G3DSA:3.30.200.20 1 89 6.5E-30 T 29-03-2018 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 231 31.93 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 Gene3D G3DSA:3.30.470.20 90 217 5.2E-49 T 29-03-2018 CWR56_RS01085 a7efe384ded9ae9a13a9011e72052fae 232 ProSitePatterns PS01057 SAICAR synthetase signature 1. 82 96 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 SUPERFAMILY SSF46785 251 320 9.36E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 Gene3D G3DSA:1.10.10.10 244 318 1.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 SMART SM00345 10 69 6.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 SMART SM00345 257 316 1.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 Gene3D G3DSA:1.10.10.10 1 82 4.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 254 316 1.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 65 6.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS02720 349932310141d9ac66c91bcde64a44df 488 SUPERFAMILY SSF46785 2 73 6.83E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18035 7ffde0dad2535f9763f0fc056c1852ed 126 Gene3D G3DSA:3.10.180.10 1 125 5.7E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS18035 7ffde0dad2535f9763f0fc056c1852ed 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 118 6.3E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR56_RS18035 7ffde0dad2535f9763f0fc056c1852ed 126 SUPERFAMILY SSF54593 1 125 2.26E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 2.0E-216 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 ProSitePatterns PS00164 Enolase signature. 336 349 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 Gene3D G3DSA:3.20.20.120 128 430 4.0E-105 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 SMART SM01192 139 427 5.2E-226 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 Gene3D G3DSA:3.30.390.10 3 126 3.7E-55 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PIRSF PIRSF001400 1 427 1.1E-194 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 Hamap MF_00318 Enolase [eno]. 2 413 46.038 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PRINTS PR00148 Enolase signature 37 51 8.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PRINTS PR00148 Enolase signature 107 123 8.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PRINTS PR00148 Enolase signature 161 174 8.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PRINTS PR00148 Enolase signature 336 350 8.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PRINTS PR00148 Enolase signature 313 324 8.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 PRINTS PR00148 Enolase signature 365 382 8.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 425 1.7E-135 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 SUPERFAMILY SSF54826 3 138 3.39E-58 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 Pfam PF03952 Enolase, N-terminal domain 4 134 6.4E-61 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 SMART SM01193 4 134 1.1E-98 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS15915 4d622e6a9237f5cff8ffea322eda9d70 430 SUPERFAMILY SSF51604 138 428 4.1E-131 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 179 284 3.3E-23 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:3.30.365.10 421 578 8.9E-41 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 SUPERFAMILY SSF54292 6 75 4.98E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:3.30.365.10 579 690 3.6E-20 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 51 1.0E-6 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:1.10.150.120 72 151 2.6E-25 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 SUPERFAMILY SSF54665 139 286 3.31E-37 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Pfam PF01799 [2Fe-2S] binding domain 70 141 5.7E-24 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:3.10.20.30 1 71 2.5E-20 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:3.30.365.10 314 420 2.8E-29 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:3.30.365.10 691 851 1.1E-27 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Gene3D G3DSA:3.90.1170.50 152 285 1.3E-34 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 SMART SM01008 177 285 2.0E-37 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 689 794 5.7E-15 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 303 682 1.3E-99 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 TIGRFAM TIGR03311 Se_dep_XDH: selenium-dependent xanthine dehydrogenase 2 851 0.0 T 29-03-2018 IPR017697 Selenium-dependent xanthine dehydrogenase CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 SUPERFAMILY SSF47741 70 155 5.68E-25 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS15950 dbe6acad5ce4604221c4fc432e94e095 853 SUPERFAMILY SSF56003 290 844 9.81E-146 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 SUPERFAMILY SSF50249 1 62 6.28E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Gene3D G3DSA:1.10.8.10 151 194 1.8E-10 T 29-03-2018 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Pfam PF14520 Helix-hairpin-helix domain 71 129 2.1E-17 T 29-03-2018 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 SUPERFAMILY SSF47781 65 135 1.43E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 28.37 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 2 195 9.6E-45 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Pfam PF01330 RuvA N terminal domain 1 59 9.6E-21 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 SMART SM00278 72 91 1.2 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 SMART SM00278 107 126 0.29 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Gene3D G3DSA:1.10.150.20 81 135 3.4E-16 T 29-03-2018 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 SUPERFAMILY SSF46929 152 194 2.75E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Gene3D G3DSA:1.10.150.280 56 80 0.12 T 29-03-2018 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Gene3D G3DSA:2.40.50.140 1 55 3.1E-22 T 29-03-2018 CWR56_RS14240 2e4cfac38df77a30670573763ad84b0a 200 Pfam PF07499 RuvA, C-terminal domain 153 194 1.7E-10 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CWR56_RS10320 a884405fac8fd44e229dd2cbe05dbb1c 352 Gene3D G3DSA:2.160.20.80 37 175 7.5E-4 T 29-03-2018 CWR56_RS10320 a884405fac8fd44e229dd2cbe05dbb1c 352 Gene3D G3DSA:1.10.287.70 220 352 1.0E-13 T 29-03-2018 CWR56_RS10320 a884405fac8fd44e229dd2cbe05dbb1c 352 SUPERFAMILY SSF81324 251 351 1.44E-14 T 29-03-2018 CWR56_RS10320 a884405fac8fd44e229dd2cbe05dbb1c 352 Pfam PF07885 Ion channel 296 351 1.5E-8 T 29-03-2018 IPR013099 Potassium channel domain CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 311 4.6E-128 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 586 660 3.0E-15 T 29-03-2018 IPR001357 BRCT domain CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:3.40.50.10190 564 664 4.9E-25 T 29-03-2018 IPR001357 BRCT domain CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 400 426 2.1E-8 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Pfam PF12826 Helix-hairpin-helix motif 502 565 1.1E-18 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SUPERFAMILY SSF50249 311 393 4.8E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:3.30.1490.70 232 314 3.3E-29 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:1.10.150.20 424 497 1.1E-27 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 10 656 2.4E-263 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:1.10.287.610 1 66 1.3E-26 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 315 391 2.1E-34 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Pfam PF14520 Helix-hairpin-helix domain 438 492 0.0018 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Hamap MF_01588 DNA ligase [ligA]. 1 660 51.646 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SMART SM00292 586 663 1.2E-16 T 29-03-2018 IPR001357 BRCT domain CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:1.10.150.20 498 563 4.5E-20 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:2.40.50.140 315 383 2.8E-32 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SMART SM00532 2 440 3.6E-261 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SUPERFAMILY SSF52113 587 662 7.1E-19 T 29-03-2018 IPR001357 BRCT domain CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SUPERFAMILY SSF56091 3 309 2.16E-120 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SMART SM00278 438 457 61.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SMART SM00278 536 555 160.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SMART SM00278 472 491 3.1 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 112 141 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 Gene3D G3DSA:3.30.470.30 116 231 7.8E-46 T 29-03-2018 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 PIRSF PIRSF001604 1 665 2.9E-258 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWR56_RS16640 32f3fbe2e8ad4f0b5393712e30fd5bfe 674 SUPERFAMILY SSF47781 397 575 2.85E-57 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS15625 efb933ed03d4f3fcb9ca8401fe53bb14 454 Pfam PF00367 phosphotransferase system, EIIB 12 43 1.3E-17 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15625 efb933ed03d4f3fcb9ca8401fe53bb14 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15625 efb933ed03d4f3fcb9ca8401fe53bb14 454 Pfam PF02378 Phosphotransferase system, EIIC 112 390 5.4E-40 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15625 efb933ed03d4f3fcb9ca8401fe53bb14 454 SUPERFAMILY SSF55604 8 80 1.83E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15625 efb933ed03d4f3fcb9ca8401fe53bb14 454 Gene3D G3DSA:3.30.1360.60 4 78 1.2E-27 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS05295 3402c7599ab167bcc96d59d38453ed8f 122 Gene3D G3DSA:3.30.110.60 1 95 2.8E-22 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR56_RS05295 3402c7599ab167bcc96d59d38453ed8f 122 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 4.1E-19 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR56_RS05295 3402c7599ab167bcc96d59d38453ed8f 122 SMART SM01103 2 85 2.9E-35 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR56_RS05295 3402c7599ab167bcc96d59d38453ed8f 122 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 93 9.0E-19 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR56_RS05295 3402c7599ab167bcc96d59d38453ed8f 122 SUPERFAMILY SSF75471 1 93 7.06E-25 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR56_RS09385 724d175008b1a050e9e37d58b619d40a 210 SUPERFAMILY SSF102198 1 209 5.1E-60 T 29-03-2018 CWR56_RS09385 724d175008b1a050e9e37d58b619d40a 210 Pfam PF04199 Putative cyclase 4 153 3.7E-29 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CWR56_RS09385 724d175008b1a050e9e37d58b619d40a 210 Gene3D G3DSA:3.50.30.50 1 210 5.7E-57 T 29-03-2018 CWR56_RS17135 d1a90aabacf66bdb07629e133a8220b4 348 Gene3D G3DSA:1.10.1610.10 5 71 1.4E-21 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17135 d1a90aabacf66bdb07629e133a8220b4 348 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 15 344 1.4E-124 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17135 d1a90aabacf66bdb07629e133a8220b4 348 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 348 33.085 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17135 d1a90aabacf66bdb07629e133a8220b4 348 SUPERFAMILY SSF52733 7 344 1.83E-110 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17135 d1a90aabacf66bdb07629e133a8220b4 348 Pfam PF02277 Phosphoribosyltransferase 12 343 1.8E-122 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17135 d1a90aabacf66bdb07629e133a8220b4 348 Gene3D G3DSA:3.40.50.10210 72 329 7.5E-98 T 29-03-2018 CWR56_RS12655 1ac6be04761738668be895c8bea94716 296 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS12655 1ac6be04761738668be895c8bea94716 296 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS12655 1ac6be04761738668be895c8bea94716 296 Gene3D G3DSA:1.10.10.60 40 128 8.0E-7 T 29-03-2018 CWR56_RS12655 1ac6be04761738668be895c8bea94716 296 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 50 2.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS12655 1ac6be04761738668be895c8bea94716 296 SUPERFAMILY SSF46689 3 69 5.64E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS12655 1ac6be04761738668be895c8bea94716 296 Gene3D G3DSA:1.10.10.60 2 39 1.0E-11 T 29-03-2018 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 528 653 7.3E-16 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Gene3D G3DSA:1.10.1790.10 166 288 9.1E-10 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Gene3D G3DSA:3.40.930.10 510 656 3.0E-19 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 SUPERFAMILY SSF55804 511 654 8.72E-20 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 SUPERFAMILY SSF63520 301 403 8.11E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 SUPERFAMILY SSF52794 409 493 6.8E-9 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 SUPERFAMILY SSF63520 185 285 3.14E-8 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Gene3D G3DSA:3.40.50.2300 409 496 2.4E-15 T 29-03-2018 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Pfam PF00874 PRD domain 312 398 3.1E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Pfam PF00874 PRD domain 207 283 5.3E-5 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Gene3D G3DSA:1.10.10.10 93 160 3.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Gene3D G3DSA:1.10.10.10 3 73 5.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Pfam PF08279 HTH domain 15 60 5.6E-8 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Pfam PF05043 Mga helix-turn-helix domain 103 170 2.2E-9 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS12195 28b36230a7cdf74ba47700dab31d4e57 657 Gene3D G3DSA:1.10.1790.10 300 403 1.3E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 3.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 3.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 PIRSF PIRSF006809 1 425 8.4E-146 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 Pfam PF13167 GTP-binding GTPase N-terminal 24 110 1.4E-30 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 Hamap MF_00900 GTPase HflX [hflX]. 25 396 45.819 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 Pfam PF16360 GTP-binding GTPase Middle Region 112 192 6.8E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 Gene3D G3DSA:1.20.120.430 47 211 0.036 T 29-03-2018 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 Gene3D G3DSA:3.40.50.300 212 373 3.6E-25 T 29-03-2018 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 SUPERFAMILY SSF52540 189 365 1.84E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 8 364 6.1E-132 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CWR56_RS10670 62d64a10827d3a965f23a1842c83aeb8 425 Pfam PF01926 50S ribosome-binding GTPase 199 325 9.1E-18 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 Gene3D G3DSA:1.10.1270.10 153 240 5.7E-19 T 29-03-2018 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 Gene3D G3DSA:1.10.601.10 37 130 2.5E-28 T 29-03-2018 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 PRINTS PR00046 Major sigma-70 factor signature 86 99 6.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 PRINTS PR00046 Major sigma-70 factor signature 184 196 6.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 PRINTS PR00046 Major sigma-70 factor signature 221 232 6.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 PRINTS PR00046 Major sigma-70 factor signature 206 221 6.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 PIRSF PIRSF000770 12 240 3.2E-60 T 29-03-2018 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 Pfam PF04542 Sigma-70 region 2 62 131 1.5E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 19 239 2.4E-112 T 29-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 SUPERFAMILY SSF88659 143 238 3.27E-19 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 62 236 1.9E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 Pfam PF04545 Sigma-70, region 4 180 234 5.5E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13375 1855baa9007e9b1444f875e7837d81ff 240 SUPERFAMILY SSF88946 37 130 3.14E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS10505 a5c32852d26d9dba966c2b06aa069948 267 SMART SM00062 34 259 1.9E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS10505 a5c32852d26d9dba966c2b06aa069948 267 Gene3D G3DSA:3.40.190.10 8 154 1.4E-35 T 29-03-2018 CWR56_RS10505 a5c32852d26d9dba966c2b06aa069948 267 SUPERFAMILY SSF53850 1 260 5.32E-61 T 29-03-2018 CWR56_RS10505 a5c32852d26d9dba966c2b06aa069948 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 258 1.1E-56 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS10505 a5c32852d26d9dba966c2b06aa069948 267 Gene3D G3DSA:3.40.190.10 155 267 1.6E-13 T 29-03-2018 CWR56_RS10505 a5c32852d26d9dba966c2b06aa069948 267 SMART SM00079 34 258 9.0E-4 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 140 154 6.3E-6 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 299 314 6.3E-6 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 251 6.3E-6 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 497 547 4.1E-13 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 SUPERFAMILY SSF53738 307 459 1.84E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 184 1.6E-40 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Gene3D G3DSA:3.30.310.50 464 566 2.1E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 SUPERFAMILY SSF53738 30 239 1.53E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 SUPERFAMILY SSF53738 216 320 5.49E-19 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Gene3D G3DSA:3.40.120.10 340 459 7.1E-37 T 29-03-2018 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 318 9.7E-24 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 327 452 1.2E-23 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Gene3D G3DSA:3.40.120.10 215 339 4.0E-26 T 29-03-2018 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 Gene3D G3DSA:3.40.120.10 17 214 2.5E-55 T 29-03-2018 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS14100 db94e4b80342537f78b2ede1a99c52a3 568 SUPERFAMILY SSF55957 450 566 9.03E-18 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 Gene3D G3DSA:3.30.230.10 1 112 1.3E-34 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 Pfam PF00825 Ribonuclease P 3 110 1.6E-33 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 SUPERFAMILY SSF54211 3 110 6.07E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 110 3.5E-29 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 52 66 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 9 108 1.0E-25 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR56_RS18430 8abd1982803b1b07d021028272a0794c 114 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 3 113 19.781 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR56_RS01230 51f371894706835eefbf54fea0168aa4 410 SUPERFAMILY SSF56059 103 307 1.01E-31 T 29-03-2018 CWR56_RS01230 51f371894706835eefbf54fea0168aa4 410 Gene3D G3DSA:3.40.50.20 1 110 1.5E-9 T 29-03-2018 CWR56_RS01230 51f371894706835eefbf54fea0168aa4 410 Pfam PF13535 ATP-grasp domain 137 279 8.6E-12 T 29-03-2018 CWR56_RS01230 51f371894706835eefbf54fea0168aa4 410 Gene3D G3DSA:3.30.470.20 178 349 2.6E-10 T 29-03-2018 CWR56_RS01230 51f371894706835eefbf54fea0168aa4 410 Gene3D G3DSA:3.30.1490.20 111 177 8.5E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 SUPERFAMILY SSF53223 6 123 7.0E-29 T 29-03-2018 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 284 9.6E-57 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7 122 8.9E-31 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 Hamap MF_01576 Bifunctional protein FolD [folD]. 5 285 32.876 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 Gene3D G3DSA:3.40.50.10860 13 141 1.8E-33 T 29-03-2018 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 241 257 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 76 103 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 35 57 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 206 235 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 111 132 8.4E-55 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 SUPERFAMILY SSF51735 124 282 7.47E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS03485 d6199fd4712e7f9bbd21ef991b74ddde 287 Gene3D G3DSA:3.40.50.720 142 266 1.6E-34 T 29-03-2018 CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 11 556 3.5E-202 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 358 414 1.1E-8 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 Pfam PF00753 Metallo-beta-lactamase superfamily 22 100 3.1E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 Gene3D G3DSA:3.60.15.10 2 451 1.1E-62 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 SUPERFAMILY SSF56281 11 427 4.31E-93 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 Hamap MF_01491 Ribonuclease J [rnj]. 6 558 46.686 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 PIRSF PIRSF004803 2 558 1.0E-241 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWR56_RS05975 7448387ed57de396baf7a697c079f9da 558 SMART SM00849 23 217 6.1E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS06255 15b0c3f39ac58ae7d10262d777daaba5 352 Gene3D G3DSA:1.20.120.20 66 289 6.5E-5 T 29-03-2018 CWR56_RS06255 15b0c3f39ac58ae7d10262d777daaba5 352 Pfam PF08006 Protein of unknown function (DUF1700) 4 75 6.9E-15 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 SUPERFAMILY SSF53784 1 401 1.31E-102 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 Gene3D G3DSA:3.40.50.450 1 260 3.0E-56 T 29-03-2018 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PIRSF PIRSF036483 1 403 6.9E-146 T 29-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 Pfam PF00365 Phosphofructokinase 5 310 2.9E-56 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 7.7E-15 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 174 190 7.7E-15 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 101 117 7.7E-15 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 285 307 7.7E-15 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 134 151 7.7E-15 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 232 244 7.7E-15 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS15535 2006384d47d6776854e6c469dcee4389 404 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 397 42.075 T 29-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 CWR56_RS09110 cf7a8829b750888c7e3cc737af7c8f14 253 PIRSF PIRSF012294 1 253 4.3E-102 T 29-03-2018 IPR009194 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT-type GO:0005524|GO:0006580|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CWR56_RS09110 cf7a8829b750888c7e3cc737af7c8f14 253 Pfam PF01923 Cobalamin adenosyltransferase 89 244 5.9E-12 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CWR56_RS09110 cf7a8829b750888c7e3cc737af7c8f14 253 SUPERFAMILY SSF89028 88 247 3.73E-11 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CWR56_RS09110 cf7a8829b750888c7e3cc737af7c8f14 253 Gene3D G3DSA:1.20.1200.10 100 253 4.0E-18 T 29-03-2018 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.176 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 SUPERFAMILY SSF50104 2 115 6.62E-47 T 29-03-2018 IPR008991 Translation protein SH3-like domain CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 PIRSF PIRSF002191 1 116 1.7E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 4.3E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 Pfam PF01245 Ribosomal protein L19 4 112 4.8E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-41 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-41 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05815 df0cabae9dfb068a0669e36037984998 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-41 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 59 72 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 5 236 34.516 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 Gene3D G3DSA:3.20.20.70 3 236 2.2E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 230 1.3E-53 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 228 1.3E-42 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 SUPERFAMILY SSF51366 6 234 3.6E-63 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS17940 7652a5fae4cd6eab2dcd70bb89e9b357 238 SMART SM00934 7 231 3.1E-81 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Gene3D G3DSA:3.30.365.10 276 435 4.2E-45 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Gene3D G3DSA:3.30.365.10 461 594 1.0E-30 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 SUPERFAMILY SSF56003 121 757 3.27E-178 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Gene3D G3DSA:3.30.365.10 595 762 5.1E-47 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 SMART SM01008 16 129 2.6E-38 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 161 695 2.3E-153 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 16 127 1.2E-27 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Gene3D G3DSA:3.90.1170.50 1 129 3.6E-27 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 Gene3D G3DSA:3.30.365.10 171 275 6.8E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09975 013b26ae69b43921136c79f68114480e 763 SUPERFAMILY SSF54665 2 145 1.11E-35 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 PIRSF PIRSF019549 1 257 1.1E-95 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 PIRSF PIRSF019549 245 315 9.0E-18 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 TIGRFAM TIGR01441 GPR: GPR endopeptidase 3 249 4.1E-86 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 Hamap MF_00626 Germination protease [gpr]. 1 317 136.269 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 Gene3D G3DSA:3.40.50.1450 1 315 1.1E-109 T 29-03-2018 IPR023430 Peptidase HybD-like domain CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 SUPERFAMILY SSF53163 2 314 6.02E-106 T 29-03-2018 IPR023430 Peptidase HybD-like domain CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 Pfam PF03418 Germination protease 10 248 7.2E-79 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 Pfam PF03418 Germination protease 249 313 1.9E-13 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS12485 e1879ba1e126934e652dd3a116196989 317 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 2 307 9.0E-84 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 Pfam PF00072 Response regulator receiver domain 5 114 6.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 SMART SM00862 147 218 2.0E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 SUPERFAMILY SSF52172 4 176 8.25E-42 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 SMART SM00448 3 113 1.0E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 218 2.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 Gene3D G3DSA:3.40.50.2300 1 119 4.0E-39 T 29-03-2018 CWR56_RS10155 5d8a82b54092cb48eef9dd246169b19c 222 Gene3D G3DSA:1.10.10.10 120 222 5.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15145 6781de9f21a67e22412b72b7268e6396 473 SUPERFAMILY SSF53300 318 412 2.04E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A CWR56_RS15145 6781de9f21a67e22412b72b7268e6396 473 Gene3D G3DSA:3.40.50.410 280 462 1.1E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A CWR56_RS15145 6781de9f21a67e22412b72b7268e6396 473 Pfam PF09967 VWA-like domain (DUF2201) 319 444 2.6E-20 T 29-03-2018 IPR018698 VWA-like domain CWR56_RS15145 6781de9f21a67e22412b72b7268e6396 473 Pfam PF13203 Putative metallopeptidase domain 95 302 6.0E-11 T 29-03-2018 IPR025154 Putative metallopeptidase domain CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 Gene3D G3DSA:3.30.70.20 1 16 3.0E-5 T 29-03-2018 CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 1.5E-18 T 29-03-2018 CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 Gene3D G3DSA:3.30.70.20 17 62 1.5E-10 T 29-03-2018 CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.9E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.9E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.9E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR56_RS07575 d6b04156a63575731ed759863d2d6d21 62 SUPERFAMILY SSF54862 4 61 6.49E-15 T 29-03-2018 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 SMART SM00028 229 262 270.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 SMART SM00028 309 342 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 SMART SM00028 263 296 25.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 Gene3D G3DSA:1.10.150.200 251 319 1.8E-4 T 29-03-2018 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 Gene3D G3DSA:1.25.40.10 320 348 0.0048 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 SUPERFAMILY SSF53448 3 155 5.44E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 Pfam PF00535 Glycosyl transferase family 2 5 145 1.5E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 SUPERFAMILY SSF81901 197 350 1.15E-14 T 29-03-2018 CWR56_RS16775 996c175b7c69f3d3d3946382a13b397b 358 Gene3D G3DSA:3.90.550.10 1 250 9.7E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS00660 eaecbd241b04bf777a75da52df95f7ca 173 TIGRFAM TIGR01918 various_sel_PB: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family 3 169 1.9E-27 T 29-03-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 CWR56_RS00660 eaecbd241b04bf777a75da52df95f7ca 173 Pfam PF07355 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 2 169 1.1E-33 T 29-03-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 CWR56_RS06190 e09ad389eedc059d32fefd552a00ec00 593 Pfam PF00580 UvrD/REP helicase N-terminal domain 199 401 2.8E-9 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR56_RS06190 e09ad389eedc059d32fefd552a00ec00 593 Gene3D G3DSA:3.40.50.300 189 384 2.2E-18 T 29-03-2018 CWR56_RS06190 e09ad389eedc059d32fefd552a00ec00 593 SUPERFAMILY SSF52540 194 577 7.16E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06190 e09ad389eedc059d32fefd552a00ec00 593 Gene3D G3DSA:3.40.50.300 385 590 1.7E-21 T 29-03-2018 CWR56_RS16345 562876ad11d218d981ac7f69b0809297 288 SUPERFAMILY SSF51004 3 285 7.06E-43 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CWR56_RS16345 562876ad11d218d981ac7f69b0809297 288 Gene3D G3DSA:2.130.10.10 87 178 1.3E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR56_RS16345 562876ad11d218d981ac7f69b0809297 288 Gene3D G3DSA:2.130.10.10 1 86 1.1E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR56_RS16345 562876ad11d218d981ac7f69b0809297 288 Gene3D G3DSA:2.130.10.10 179 288 6.9E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR56_RS05640 bc48ad0b3d7267e4e99b968effc0225b 475 Pfam PF03413 Peptidase propeptide and YPEB domain 407 473 5.1E-8 T 29-03-2018 IPR025711 PepSY domain CWR56_RS05640 bc48ad0b3d7267e4e99b968effc0225b 475 Gene3D G3DSA:3.10.450.40 406 475 7.8E-4 T 29-03-2018 CWR56_RS05640 bc48ad0b3d7267e4e99b968effc0225b 475 Pfam PF04122 Putative cell wall binding repeat 2 218 287 2.2E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS05640 bc48ad0b3d7267e4e99b968effc0225b 475 Pfam PF04122 Putative cell wall binding repeat 2 128 210 1.2E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS05640 bc48ad0b3d7267e4e99b968effc0225b 475 Pfam PF04122 Putative cell wall binding repeat 2 33 113 1.3E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS15385 afa6ed403edd5b57808b6f0c37ffc32d 117 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 14 106 6.2E-27 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS15385 afa6ed403edd5b57808b6f0c37ffc32d 117 SUPERFAMILY SSF46973 9 107 1.19E-27 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS15385 afa6ed403edd5b57808b6f0c37ffc32d 117 PIRSF PIRSF000699 5 114 1.5E-27 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS15385 afa6ed403edd5b57808b6f0c37ffc32d 117 Gene3D G3DSA:1.20.58.80 10 108 1.4E-27 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS04025 d707f8bf91c2671bfb64dc3278b4460b 307 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04025 d707f8bf91c2671bfb64dc3278b4460b 307 Gene3D G3DSA:3.40.50.300 1 258 2.1E-58 T 29-03-2018 CWR56_RS04025 d707f8bf91c2671bfb64dc3278b4460b 307 SMART SM00382 30 213 3.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04025 d707f8bf91c2671bfb64dc3278b4460b 307 Pfam PF00005 ABC transporter 22 162 8.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04025 d707f8bf91c2671bfb64dc3278b4460b 307 SUPERFAMILY SSF52540 3 229 8.51E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 7 169 25.074 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 Pfam PF01782 RimM N-terminal domain 10 90 3.6E-23 T 29-03-2018 IPR002676 RimM protein GO:0006364 CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 Gene3D G3DSA:2.30.30.240 95 164 2.2E-20 T 29-03-2018 CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 SUPERFAMILY SSF50447 8 90 1.84E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 SUPERFAMILY SSF50346 99 168 1.08E-18 T 29-03-2018 IPR011033 PRC-barrel-like CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 Gene3D G3DSA:2.40.30.60 5 94 1.5E-24 T 29-03-2018 IPR002676 RimM protein GO:0006364 CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 8 168 9.1E-48 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CWR56_RS05805 d598ecb48d4f25cba8b412cde42774ec 171 Pfam PF05239 PRC-barrel domain 96 169 2.6E-11 T 29-03-2018 IPR027275 PRC-barrel domain CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 Gene3D G3DSA:2.30.22.10 150 205 2.5E-19 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 PRINTS PR00773 GrpE protein signature 158 173 3.5E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 PRINTS PR00773 GrpE protein signature 78 94 3.5E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 PRINTS PR00773 GrpE protein signature 106 121 3.5E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 PRINTS PR00773 GrpE protein signature 185 204 3.5E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 Hamap MF_01151 Protein GrpE [grpE]. 8 206 20.133 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 Pfam PF01025 GrpE 39 205 8.0E-45 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 Gene3D G3DSA:3.90.20.20 1 149 7.5E-23 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 SUPERFAMILY SSF58014 64 150 2.75E-25 T 29-03-2018 CWR56_RS12445 bb3732a8e862f3009870479ff8f905de 206 SUPERFAMILY SSF51064 151 205 2.09E-15 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 SUPERFAMILY SSF160996 192 354 1.96E-38 T 29-03-2018 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 Gene3D G3DSA:3.50.50.60 2 407 7.0E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 Pfam PF03486 HI0933-like protein 3 405 2.9E-136 T 29-03-2018 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.6E-9 T 29-03-2018 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.6E-9 T 29-03-2018 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 361 383 2.6E-9 T 29-03-2018 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 SUPERFAMILY SSF51905 2 191 3.71E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 SUPERFAMILY SSF51905 351 406 3.71E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 405 5.2E-140 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PIRSF PIRSF038984 274 393 20.0 T 29-03-2018 IPR028348 FAD dependent protein CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PIRSF PIRSF038984 1 216 1.5E-15 T 29-03-2018 IPR028348 FAD dependent protein CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 1.4E-6 T 29-03-2018 CWR56_RS13610 71ea4e7bed21c17b2f78115f93f91d53 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.4E-6 T 29-03-2018 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 SMART SM00382 74 210 6.2E-23 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 ProSitePatterns PS00674 AAA-protein family signature. 178 196 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 465 30.267 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 Gene3D G3DSA:1.10.8.60 226 301 1.7E-22 T 29-03-2018 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 78 207 7.5E-47 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 34 461 5.0E-174 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 Gene3D G3DSA:3.40.50.300 17 225 2.1E-62 T 29-03-2018 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 SUPERFAMILY SSF52540 37 302 7.48E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 Pfam PF01434 Peptidase family M41 269 460 1.5E-58 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CWR56_RS03275 e4508913edbf5c812a94f73e08ec2887 467 SUPERFAMILY SSF140990 292 463 1.96E-56 T 29-03-2018 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 Gene3D G3DSA:3.90.70.10 85 256 1.2E-24 T 29-03-2018 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 Gene3D G3DSA:2.40.50.170 257 318 2.5E-16 T 29-03-2018 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 Pfam PF04122 Putative cell wall binding repeat 2 500 584 2.7E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 Pfam PF04122 Putative cell wall binding repeat 2 694 779 7.3E-8 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 Pfam PF04122 Putative cell wall binding repeat 2 596 685 1.4E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 Pfam PF00112 Papain family cysteine protease 86 307 1.1E-21 T 29-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 SUPERFAMILY SSF54001 78 306 2.85E-45 T 29-03-2018 CWR56_RS08405 436bfbabeceb53b47c6ef45788c98212 795 SMART SM00645 85 319 9.3E-8 T 29-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CWR56_RS16485 880d0e7bace66897a7780e497416e5b0 140 Gene3D G3DSA:3.40.50.510 1 139 1.3E-29 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS16485 880d0e7bace66897a7780e497416e5b0 140 SUPERFAMILY SSF53062 1 131 1.83E-32 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS16485 880d0e7bace66897a7780e497416e5b0 140 Pfam PF03610 PTS system fructose IIA component 4 104 7.9E-17 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 SMART SM00851 14 107 2.8E-18 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 Pfam PF02142 MGS-like domain 22 107 1.1E-15 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 32.757 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 SUPERFAMILY SSF52335 1 131 3.14E-50 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 121 9.9E-53 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 PIRSF PIRSF006614 1 136 8.0E-57 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CWR56_RS05235 f140581e10ca4559dc5e6677c0f7defb 137 Gene3D G3DSA:3.40.50.1380 1 135 3.2E-36 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 SUPERFAMILY SSF54713 152 302 5.23E-51 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 Gene3D G3DSA:3.30.479.20 153 301 3.9E-52 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 Gene3D G3DSA:3.30.479.20 57 150 5.5E-19 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 SUPERFAMILY SSF54713 56 146 7.46E-19 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 Gene3D G3DSA:1.10.8.10 1 56 1.5E-25 T 29-03-2018 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 Pfam PF00889 Elongation factor TS 73 285 4.7E-72 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 Hamap MF_00050 Elongation factor Ts [tsf]. 1 302 78.281 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 SUPERFAMILY SSF46934 4 55 9.87E-20 T 29-03-2018 IPR009060 UBA-like GO:0005515 CWR56_RS10305 0ef76b26104950f741cdec57f3a22d88 303 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 303 3.9E-103 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Gene3D G3DSA:3.30.70.100 83 167 2.8E-11 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF55008 4 70 7.59E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 511 2.9E-21 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 644 2.9E-21 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 714 726 2.9E-21 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 2.9E-21 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 690 709 2.9E-21 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 493 704 1.3E-34 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 246 792 9.5E-170 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 274 770 5.8E-74 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF55008 91 151 7.33E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 246 795 1.7E-152 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Gene3D G3DSA:3.40.1110.10 510 654 1.4E-31 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00941 Cadmium-transporting ATPase signature 380 394 3.9E-10 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00941 Cadmium-transporting ATPase signature 106 127 3.9E-10 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00941 Cadmium-transporting ATPase signature 208 225 3.9E-10 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00941 Cadmium-transporting ATPase signature 280 300 3.9E-10 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 PRINTS PR00941 Cadmium-transporting ATPase signature 361 377 3.9E-10 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Gene3D G3DSA:1.20.1110.10 655 794 1.9E-26 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Gene3D G3DSA:3.30.70.100 6 82 3.1E-10 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 499 505 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF81653 298 395 1.7E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Pfam PF00403 Heavy-metal-associated domain 11 70 1.3E-7 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Pfam PF00403 Heavy-metal-associated domain 98 152 1.0E-8 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Gene3D G3DSA:1.20.1110.10 184 509 5.1E-32 T 29-03-2018 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF56784 495 515 1.91E-59 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF56784 552 791 1.91E-59 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF81665 396 490 1.83E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 SUPERFAMILY SSF81665 230 252 1.83E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS01615 a182dfbc2afb9aa1b62dad620e1ba98a 795 Pfam PF00122 E1-E2 ATPase 296 476 1.8E-45 T 29-03-2018 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 482 31.05 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 PRINTS PR00481 Cytosol aminopeptidase signature 270 291 4.7E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 PRINTS PR00481 Cytosol aminopeptidase signature 307 328 4.7E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 PRINTS PR00481 Cytosol aminopeptidase signature 248 265 4.7E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 PRINTS PR00481 Cytosol aminopeptidase signature 329 349 4.7E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 PRINTS PR00481 Cytosol aminopeptidase signature 358 373 4.7E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 Gene3D G3DSA:3.40.630.10 157 483 5.7E-120 T 29-03-2018 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 172 477 1.7E-111 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 Gene3D G3DSA:3.40.220.10 1 149 3.4E-14 T 29-03-2018 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 SUPERFAMILY SSF52949 1 169 8.83E-15 T 29-03-2018 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 41 137 1.0E-12 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 SUPERFAMILY SSF53187 166 480 1.1E-105 T 29-03-2018 CWR56_RS06030 e5378a72754dbceade6f8969747ef33f 483 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 333 340 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CWR56_RS07585 f537ad394ecd835559c51e545d372d51 416 SUPERFAMILY SSF55486 172 412 1.32E-25 T 29-03-2018 CWR56_RS07585 f537ad394ecd835559c51e545d372d51 416 Gene3D G3DSA:3.40.390.10 185 412 1.6E-30 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CWR56_RS00580 ca960470c8bffe5fff9af019f905f587 245 Pfam PF08680 TATA-box binding 56 245 5.6E-42 T 29-03-2018 IPR014794 TATA-box binding CWR56_RS00580 ca960470c8bffe5fff9af019f905f587 245 Gene3D G3DSA:3.30.360.40 174 245 4.7E-21 T 29-03-2018 CWR56_RS00580 ca960470c8bffe5fff9af019f905f587 245 SUPERFAMILY SSF143842 40 241 1.15E-48 T 29-03-2018 IPR014794 TATA-box binding CWR56_RS15740 b2f5b4dcc19b0ada9f65bbc14e3843cb 488 Gene3D G3DSA:3.40.50.620 5 290 1.4E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS15740 b2f5b4dcc19b0ada9f65bbc14e3843cb 488 TIGRFAM TIGR03183 DNA_S_dndC: putative sulfurtransferase DndC 16 464 4.6E-127 T 29-03-2018 IPR017598 Sulphur transferase DndC, putative CWR56_RS15740 b2f5b4dcc19b0ada9f65bbc14e3843cb 488 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 30 216 6.1E-7 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CWR56_RS15740 b2f5b4dcc19b0ada9f65bbc14e3843cb 488 SUPERFAMILY SSF52402 12 216 3.35E-18 T 29-03-2018 CWR56_RS13925 48cb3bccfc2244ddbc88fdf272a0777d 816 Pfam PF01368 DHH family 78 213 1.6E-12 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS13925 48cb3bccfc2244ddbc88fdf272a0777d 816 Gene3D G3DSA:3.90.1640.10 58 333 1.9E-27 T 29-03-2018 CWR56_RS13925 48cb3bccfc2244ddbc88fdf272a0777d 816 SUPERFAMILY SSF64182 53 449 8.37E-119 T 29-03-2018 CWR56_RS13925 48cb3bccfc2244ddbc88fdf272a0777d 816 Pfam PF02272 DHHA1 domain 315 438 1.1E-21 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR56_RS13925 48cb3bccfc2244ddbc88fdf272a0777d 816 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 24 560 2.1E-182 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SUPERFAMILY SSF47384 647 726 1.41E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Gene3D G3DSA:3.30.450.20 412 465 2.0E-4 T 29-03-2018 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Gene3D G3DSA:3.30.450.20 466 515 0.029 T 29-03-2018 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Gene3D G3DSA:3.30.450.20 516 645 7.7E-11 T 29-03-2018 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Gene3D G3DSA:3.30.565.10 740 909 4.8E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SUPERFAMILY SSF55785 404 505 7.8E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SUPERFAMILY SSF55874 715 883 3.89E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SUPERFAMILY SSF55785 297 340 7.8E-5 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Pfam PF00512 His Kinase A (phospho-acceptor) domain 655 726 3.5E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Pfam PF13188 PAS domain 521 568 0.0019 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SMART SM00387 772 884 5.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SMART SM00388 654 726 9.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SUPERFAMILY SSF55785 505 631 1.26E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 773 882 6.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SMART SM00091 519 588 7.3 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 SMART SM00091 302 372 0.018 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Pfam PF13426 PAS domain 313 352 0.0043 T 29-03-2018 IPR000014 PAS domain CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 827 837 3.5E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 881 3.5E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 862 3.5E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 823 3.5E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Gene3D G3DSA:1.10.287.130 646 722 4.4E-13 T 29-03-2018 CWR56_RS12595 264b1637f6b2425316d56ab7622c53a5 912 Gene3D G3DSA:3.30.450.20 297 411 3.6E-7 T 29-03-2018 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 35 51 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 Pfam PF00682 HMGL-like 28 304 1.7E-72 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 Gene3D G3DSA:3.20.20.70 5 373 2.0E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 SUPERFAMILY SSF110921 459 558 8.24E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 Pfam PF08502 LeuA allosteric (dimerisation) domain 419 559 9.4E-25 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 SUPERFAMILY SSF51569 17 325 5.86E-98 T 29-03-2018 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 SUPERFAMILY SSF89000 386 435 5.1E-12 T 29-03-2018 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 561 51.076 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 4 558 1.3E-226 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04485 edcfce5d74fd7e7d83558e9b4b2a7520 580 SMART SM00917 419 560 8.2E-27 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 1.1E-168 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 Gene3D G3DSA:1.10.287.40 2 105 2.4E-23 T 29-03-2018 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 41.987 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 SUPERFAMILY SSF55681 117 422 3.69E-102 T 29-03-2018 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 400 3.6E-36 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 3.3E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 3.3E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 3.3E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 3.3E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 3.3E-31 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 Gene3D G3DSA:3.30.930.10 106 423 2.1E-97 T 29-03-2018 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 SUPERFAMILY SSF46589 1 113 2.25E-27 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 PIRSF PIRSF001529 1 423 5.0E-180 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS18550 adb4e2110b6b08a9337880b5826ace84 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 2.3E-28 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 PIRSF PIRSF006621 1 322 2.8E-114 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 Pfam PF01207 Dihydrouridine synthase (Dus) 14 314 2.0E-107 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 318 2.0E-129 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 Gene3D G3DSA:3.20.20.70 8 241 1.6E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 SUPERFAMILY SSF51395 10 317 5.49E-95 T 29-03-2018 CWR56_RS17745 1fae29ba03f9d1eb99983c89633f5c68 322 Gene3D G3DSA:1.10.1200.80 251 321 3.2E-20 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SUPERFAMILY SSF54980 401 478 1.91E-24 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SUPERFAMILY SSF50447 264 401 5.42E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SUPERFAMILY SSF54211 476 595 4.05E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SUPERFAMILY SSF54980 600 685 1.01E-31 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Pfam PF03144 Elongation factor Tu domain 2 321 388 1.5E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Gene3D G3DSA:3.30.230.10 489 610 7.0E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Gene3D G3DSA:3.30.70.240 611 688 2.5E-31 T 29-03-2018 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SMART SM00838 597 684 1.4E-59 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 5.7E-64 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SUPERFAMILY SSF52540 6 279 1.12E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Pfam PF00679 Elongation factor G C-terminus 597 683 1.4E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 SMART SM00889 477 595 3.9E-69 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Pfam PF03764 Elongation factor G, domain IV 476 594 6.8E-46 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Pfam PF14492 Elongation Factor G, domain II 401 474 1.7E-34 T 29-03-2018 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.4E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 3.4E-35 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 686 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Gene3D G3DSA:2.40.30.10 291 396 1.3E-31 T 29-03-2018 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Gene3D G3DSA:3.30.70.870 397 488 7.8E-36 T 29-03-2018 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Gene3D G3DSA:3.40.50.300 1 285 6.6E-59 T 29-03-2018 CWR56_RS00070 ba775bd5108fb1eb93cc9fe05eb6c016 688 Hamap MF_00054_B Elongation factor G [fusA]. 6 688 110.951 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 SMART SM00871 124 275 1.8E-4 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 Pfam PF13411 MerR HTH family regulatory protein 9 76 2.4E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 Gene3D G3DSA:1.10.1660.10 5 78 6.6E-20 T 29-03-2018 CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 SUPERFAMILY SSF55136 141 274 6.98E-20 T 29-03-2018 CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 SMART SM00422 9 78 2.6E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 Pfam PF06445 GyrI-like small molecule binding domain 209 257 9.3E-7 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 Gene3D G3DSA:3.20.80.10 83 276 8.3E-18 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS04630 abbbc55f15514d9e1686b9ce41e98d13 276 SUPERFAMILY SSF46955 9 122 1.47E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 Gene3D G3DSA:3.40.50.300 1 258 2.2E-46 T 29-03-2018 CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 Gene3D G3DSA:3.40.50.300 259 491 2.4E-34 T 29-03-2018 CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 SUPERFAMILY SSF52540 253 485 1.05E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 Pfam PF00005 ABC transporter 20 169 5.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 Pfam PF00005 ABC transporter 273 427 1.5E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 SUPERFAMILY SSF52540 4 229 1.06E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 SMART SM00382 29 232 0.0051 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07525 0f61cf7178380f4a98090c2544f6e1ea 498 SMART SM00382 282 475 0.024 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 511 54.638 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Gene3D G3DSA:3.40.50.620 223 379 1.1E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Pfam PF00958 GMP synthase C terminal domain 419 510 3.5E-45 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Gene3D G3DSA:3.40.50.880 1 222 3.2E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Pfam PF00117 Glutamine amidotransferase class-I 8 188 4.5E-40 T 29-03-2018 IPR017926 Glutamine amidotransferase CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 SUPERFAMILY SSF52402 181 432 2.05E-55 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 SUPERFAMILY SSF52317 4 225 1.41E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 201 511 2.1E-153 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Pfam PF02540 NAD synthase 202 280 1.5E-5 T 29-03-2018 IPR022310 NAD/GMP synthase CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 Gene3D G3DSA:3.30.300.10 387 511 1.9E-55 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 7.6E-6 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 7.6E-6 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 7.6E-6 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 6 20 5.8E-6 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 5.8E-6 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 5.8E-6 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 SUPERFAMILY SSF54810 391 511 7.72E-53 T 29-03-2018 CWR56_RS00985 ac71933ba988b752622a0f90c85128c9 511 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 192 1.8E-74 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 282 308 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 Gene3D G3DSA:3.40.50.620 4 211 2.8E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 218 301 7.2E-39 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 SUPERFAMILY SSF52467 218 337 3.74E-50 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 SUPERFAMILY SSF52402 17 210 1.6E-56 T 29-03-2018 CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 PIRSF PIRSF000089 14 340 3.8E-123 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 Gene3D G3DSA:3.40.50.1220 214 340 1.3E-61 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 SMART SM00893 18 207 1.4E-56 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS03935 2b00f768b037f30ab8e95193ec4f66b7 340 Pfam PF01012 Electron transfer flavoprotein domain 18 196 1.4E-47 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS10005 3550748daa7c904f226bcb0e6a839b9b 404 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 24 398 5.1E-179 T 29-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 CWR56_RS10005 3550748daa7c904f226bcb0e6a839b9b 404 Gene3D G3DSA:3.40.50.1100 184 396 8.6E-29 T 29-03-2018 CWR56_RS10005 3550748daa7c904f226bcb0e6a839b9b 404 Gene3D G3DSA:3.40.50.1100 1 183 4.6E-31 T 29-03-2018 CWR56_RS10005 3550748daa7c904f226bcb0e6a839b9b 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 40 383 1.5E-48 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS10005 3550748daa7c904f226bcb0e6a839b9b 404 SUPERFAMILY SSF53686 18 397 5.89E-56 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS10005 3550748daa7c904f226bcb0e6a839b9b 404 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 4 399 2.9E-198 T 29-03-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 Pfam PF00571 CBS domain 80 132 2.5E-7 T 29-03-2018 IPR000644 CBS domain CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 Pfam PF00571 CBS domain 147 206 8.6E-5 T 29-03-2018 IPR000644 CBS domain CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 PIRSF PIRSF026546 4 212 2.6E-88 T 29-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 Pfam PF08279 HTH domain 9 61 3.0E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 SMART SM00116 86 134 0.048 T 29-03-2018 IPR000644 CBS domain CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 SMART SM00116 153 207 0.012 T 29-03-2018 IPR000644 CBS domain CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 SUPERFAMILY SSF46785 6 67 1.89E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 SUPERFAMILY SSF54631 71 208 2.9E-22 T 29-03-2018 CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 Gene3D G3DSA:3.10.580.10 66 212 1.3E-25 T 29-03-2018 CWR56_RS12175 228d4f63a5b0770d58f321bf2958de99 212 Gene3D G3DSA:1.10.10.10 2 64 4.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08785 6513d9e027fe6c364b9b0097e2507527 154 PIRSF PIRSF000239 1 153 3.8E-26 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR56_RS08785 6513d9e027fe6c364b9b0097e2507527 154 Gene3D G3DSA:3.40.30.10 1 152 6.4E-46 T 29-03-2018 CWR56_RS08785 6513d9e027fe6c364b9b0097e2507527 154 Pfam PF00578 AhpC/TSA family 4 132 1.1E-41 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR56_RS08785 6513d9e027fe6c364b9b0097e2507527 154 SUPERFAMILY SSF52833 1 152 4.55E-55 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS00240 5b46c376a30989f218a465a8fe2b69a6 277 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS00240 5b46c376a30989f218a465a8fe2b69a6 277 SMART SM00382 33 219 3.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00240 5b46c376a30989f218a465a8fe2b69a6 277 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 275 8.7E-123 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CWR56_RS00240 5b46c376a30989f218a465a8fe2b69a6 277 Gene3D G3DSA:3.40.50.300 1 242 1.5E-65 T 29-03-2018 CWR56_RS00240 5b46c376a30989f218a465a8fe2b69a6 277 SUPERFAMILY SSF52540 2 235 4.28E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00240 5b46c376a30989f218a465a8fe2b69a6 277 Pfam PF00005 ABC transporter 25 171 2.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Gene3D G3DSA:3.40.350.10 161 297 2.1E-26 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 SUPERFAMILY SSF55920 304 563 1.57E-50 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 132 3.9E-16 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 SUPERFAMILY SSF53092 10 132 2.27E-14 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Pfam PF16189 Creatinase/Prolidase N-terminal domain 149 307 5.9E-51 T 29-03-2018 CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Gene3D G3DSA:3.40.350.10 1 147 1.2E-48 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Gene3D G3DSA:3.90.230.10 302 555 7.7E-55 T 29-03-2018 CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 SUPERFAMILY SSF53092 177 283 6.63E-5 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Pfam PF16188 C-terminal region of peptidase_M24 537 597 1.9E-19 T 29-03-2018 IPR032416 Peptidase M24, C-terminal domain CWR56_RS11210 64f30bbcd6ef4c0be52ab36e4781c10b 597 Pfam PF00557 Metallopeptidase family M24 309 528 4.6E-38 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS15425 201a00232b10deae923c7d4b50a1f86f 256 SUPERFAMILY SSF88713 1 249 6.67E-55 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS15425 201a00232b10deae923c7d4b50a1f86f 256 Gene3D G3DSA:3.20.20.370 1 251 7.7E-53 T 29-03-2018 CWR56_RS15425 201a00232b10deae923c7d4b50a1f86f 256 Pfam PF04794 YdjC-like protein 3 237 4.7E-44 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like CWR56_RS14490 7656983b5b02b3d138a73825d63b8a35 76 SUPERFAMILY SSF47336 2 74 3.4E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR56_RS14490 7656983b5b02b3d138a73825d63b8a35 76 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 3 73 1.8E-17 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CWR56_RS14490 7656983b5b02b3d138a73825d63b8a35 76 Pfam PF00550 Phosphopantetheine attachment site 4 72 6.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR56_RS14490 7656983b5b02b3d138a73825d63b8a35 76 Gene3D G3DSA:1.10.1200.10 1 76 3.3E-14 T 29-03-2018 CWR56_RS14490 7656983b5b02b3d138a73825d63b8a35 76 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 76 37.031 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CWR56_RS10960 410860f5b4335bcdcbc24b7405405322 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 1.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10960 410860f5b4335bcdcbc24b7405405322 195 Gene3D G3DSA:1.10.10.60 4 52 2.3E-10 T 29-03-2018 CWR56_RS10960 410860f5b4335bcdcbc24b7405405322 195 SUPERFAMILY SSF46689 5 77 4.0E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS10960 410860f5b4335bcdcbc24b7405405322 195 Gene3D G3DSA:1.10.10.60 53 177 8.2E-6 T 29-03-2018 CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 Gene3D G3DSA:3.30.565.10 181 333 1.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 SUPERFAMILY SSF47384 115 174 3.34E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 221 329 6.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 Gene3D G3DSA:1.10.287.130 106 172 0.0019 T 29-03-2018 CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 SUPERFAMILY SSF55874 183 330 1.27E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 SMART SM00387 220 332 1.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 310 5.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 329 5.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 258 272 5.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14930 de7dea202b2c2e22d8eb470068e8fdd1 335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 286 5.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS15170 4220ad1da3071385b784e240ea1c5963 353 SUPERFAMILY SSF54001 67 182 6.87E-13 T 29-03-2018 CWR56_RS15170 4220ad1da3071385b784e240ea1c5963 353 Pfam PF01841 Transglutaminase-like superfamily 78 149 2.7E-6 T 29-03-2018 IPR002931 Transglutaminase-like CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 SUPERFAMILY SSF51556 62 370 2.46E-90 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 Gene3D G3DSA:2.30.40.10 390 449 0.29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 Gene3D G3DSA:2.30.40.10 1 75 9.3E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 SUPERFAMILY SSF51338 3 62 1.36E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 SUPERFAMILY SSF51338 369 445 1.36E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 Pfam PF01979 Amidohydrolase family 59 418 5.4E-65 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS10025 394c2f4203e1084b237e7c828781e945 464 Gene3D G3DSA:3.20.20.140 76 387 1.6E-61 T 29-03-2018 CWR56_RS17155 a7e688111a62d2037c4dbc25f92f38e1 395 Pfam PF00155 Aminotransferase class I and II 47 386 2.9E-33 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS17155 a7e688111a62d2037c4dbc25f92f38e1 395 Gene3D G3DSA:3.90.1150.10 278 394 3.9E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS17155 a7e688111a62d2037c4dbc25f92f38e1 395 SUPERFAMILY SSF53383 1 389 2.66E-87 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS17155 a7e688111a62d2037c4dbc25f92f38e1 395 Gene3D G3DSA:3.90.1150.10 1 109 3.6E-11 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS17155 a7e688111a62d2037c4dbc25f92f38e1 395 Gene3D G3DSA:3.40.640.10 110 277 1.0E-20 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS17155 a7e688111a62d2037c4dbc25f92f38e1 395 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 388 3.9E-111 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR56_RS15925 12645e32d5d37e87519e6a3170fb28f3 247 Pfam PF00121 Triosephosphate isomerase 5 245 1.6E-96 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15925 12645e32d5d37e87519e6a3170fb28f3 247 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15925 12645e32d5d37e87519e6a3170fb28f3 247 SUPERFAMILY SSF51351 1 246 1.7E-96 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15925 12645e32d5d37e87519e6a3170fb28f3 247 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 237 7.1E-60 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15925 12645e32d5d37e87519e6a3170fb28f3 247 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 247 39.992 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15925 12645e32d5d37e87519e6a3170fb28f3 247 Gene3D G3DSA:3.20.20.70 1 247 2.3E-104 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 Gene3D G3DSA:3.90.230.10 28 289 3.3E-77 T 29-03-2018 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 Hamap MF_01974 Methionine aminopeptidase [map]. 43 289 37.422 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 SUPERFAMILY SSF103642 4 24 1.54E-7 T 29-03-2018 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 Gene3D G3DSA:3.10.450.50 1 25 3.8E-9 T 29-03-2018 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 107 120 4.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 130 146 4.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 231 243 4.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 4.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 Pfam PF02810 SEC-C motif 5 22 2.0E-8 T 29-03-2018 IPR004027 SEC-C motif CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 44 289 1.3E-88 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 Pfam PF00557 Metallopeptidase family M24 51 281 3.4E-49 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS07580 0f1923c4f1b3274c2229cec10cfe5df6 289 SUPERFAMILY SSF55920 44 288 1.44E-79 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 Gene3D G3DSA:2.30.24.10 5 62 1.8E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 SMART SM01061 8 66 5.5E-26 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 Pfam PF03123 CAT RNA binding domain 8 63 5.1E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 Pfam PF00874 PRD domain 187 280 1.5E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 Pfam PF00874 PRD domain 83 170 7.4E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 SUPERFAMILY SSF63520 180 281 1.7E-26 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 Gene3D G3DSA:1.10.1790.10 173 284 1.0E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 Gene3D G3DSA:1.10.1790.10 63 172 2.0E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 SUPERFAMILY SSF63520 65 173 1.11E-31 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15620 4950d98df85cbc45fb4f8e5e3cf402c9 287 SUPERFAMILY SSF50151 8 61 1.57E-17 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Gene3D G3DSA:3.40.50.300 1 171 2.0E-38 T 29-03-2018 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 PIRSF PIRSF005719 1 1182 1.4E-294 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1174 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 634 4.2E-30 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 SUPERFAMILY SSF75553 486 684 9.42E-53 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1176 23.065 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Gene3D G3DSA:1.20.1170.10 423 784 3.6E-18 T 29-03-2018 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 SMART SM00968 520 636 5.3E-37 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1167 1.8E-50 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Gene3D G3DSA:3.40.50.300 933 1183 1.8E-29 T 29-03-2018 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 SUPERFAMILY SSF57997 681 913 3.14E-7 T 29-03-2018 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 SUPERFAMILY SSF52540 1 214 3.3E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 SUPERFAMILY SSF52540 1073 1159 3.3E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Gene3D G3DSA:1.20.5.340 785 924 3.2E-5 T 29-03-2018 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Gene3D G3DSA:1.20.120.330 172 291 0.049 T 29-03-2018 CWR56_RS05775 3358235aa84ae3adc109427bf2694870 1184 Gene3D G3DSA:1.20.120.330 292 422 1.2E-5 T 29-03-2018 CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 SUPERFAMILY SSF46548 216 328 8.89E-17 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 Gene3D G3DSA:3.30.70.20 133 229 0.0028 T 29-03-2018 CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 TIGRFAM TIGR02910 sulfite_red_A: sulfite reductase, subunit A 1 329 3.6E-149 T 29-03-2018 IPR014259 Sulphite reductase, subunit A CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 Gene3D G3DSA:3.30.70.20 230 306 1.5E-7 T 29-03-2018 CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 Pfam PF17179 4Fe-4S dicluster domain 220 316 2.4E-34 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 221 232 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS10805 89c8df3c6306723a6ad461a83920c663 335 Gene3D G3DSA:3.30.70.20 307 333 0.011 T 29-03-2018 CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 SUPERFAMILY SSF103642 7 27 1.41E-7 T 29-03-2018 CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 Gene3D G3DSA:1.10.472.10 261 348 0.0031 T 29-03-2018 IPR013763 Cyclin-like CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 Pfam PF05225 helix-turn-helix, Psq domain 308 344 1.3E-5 T 29-03-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 Gene3D G3DSA:3.10.450.50 22 132 6.6E-4 T 29-03-2018 CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 Pfam PF02810 SEC-C motif 8 25 7.3E-10 T 29-03-2018 IPR004027 SEC-C motif CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 SUPERFAMILY SSF47954 278 346 4.34E-5 T 29-03-2018 IPR013763 Cyclin-like CWR56_RS16545 5f9903c199dae61f7b637e278baee3cb 349 Gene3D G3DSA:3.10.450.50 5 21 1.3E-8 T 29-03-2018 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 SMART SM00382 122 247 5.1E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 Pfam PF00437 Type II/IV secretion system protein 13 264 2.5E-48 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 Gene3D G3DSA:3.30.450.90 1 100 3.4E-21 T 29-03-2018 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 Gene3D G3DSA:3.40.50.300 113 272 2.0E-30 T 29-03-2018 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 Gene3D G3DSA:3.40.50.300 273 347 6.5E-14 T 29-03-2018 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 4.5E-142 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 CWR56_RS17480 0d1c7e8c9c7a531d8b120825064c469f 360 SUPERFAMILY SSF52540 5 336 9.49E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 224 292 1.6E-10 T 29-03-2018 IPR006343 DnaD domain CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 SUPERFAMILY SSF158499 230 287 1.44E-13 T 29-03-2018 IPR006343 DnaD domain CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 Gene3D G3DSA:1.10.10.630 215 294 1.2E-16 T 29-03-2018 IPR034829 DnaD-like domain CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 Gene3D G3DSA:1.10.10.630 130 209 7.6E-20 T 29-03-2018 IPR034829 DnaD-like domain CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 PIRSF PIRSF033722 1 349 2.4E-52 T 29-03-2018 IPR017019 Predicted DNA replication protein, bacterial CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 Pfam PF07261 Replication initiation and membrane attachment 227 295 2.3E-14 T 29-03-2018 IPR006343 DnaD domain CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 Pfam PF07261 Replication initiation and membrane attachment 136 209 2.9E-18 T 29-03-2018 IPR006343 DnaD domain CWR56_RS18270 ee8086f6e1b6121d9530cab15beb61ab 352 SUPERFAMILY SSF158499 136 203 1.19E-11 T 29-03-2018 IPR006343 DnaD domain CWR56_RS01925 fc85c8630926926e59f8dd4a6ddb0033 308 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 305 5.9E-88 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS01925 fc85c8630926926e59f8dd4a6ddb0033 308 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 306 6.2E-105 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CWR56_RS01925 fc85c8630926926e59f8dd4a6ddb0033 308 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 305 2.8E-98 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS01925 fc85c8630926926e59f8dd4a6ddb0033 308 SUPERFAMILY SSF51569 3 305 3.08E-102 T 29-03-2018 CWR56_RS01925 fc85c8630926926e59f8dd4a6ddb0033 308 PIRSF PIRSF001359 1 307 2.6E-99 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS01925 fc85c8630926926e59f8dd4a6ddb0033 308 Gene3D G3DSA:3.20.20.70 1 308 4.8E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS14390 db17907ceeaa159c0b4cc554161f59ba 418 Gene3D G3DSA:3.90.1150.10 270 411 5.8E-49 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS14390 db17907ceeaa159c0b4cc554161f59ba 418 Pfam PF00464 Serine hydroxymethyltransferase 8 380 8.0E-138 T 29-03-2018 CWR56_RS14390 db17907ceeaa159c0b4cc554161f59ba 418 SUPERFAMILY SSF53383 5 412 4.03E-150 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS14390 db17907ceeaa159c0b4cc554161f59ba 418 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 43.501 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR56_RS14390 db17907ceeaa159c0b4cc554161f59ba 418 PIRSF PIRSF000412 1 414 9.2E-142 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR56_RS14390 db17907ceeaa159c0b4cc554161f59ba 418 Gene3D G3DSA:3.40.640.10 34 269 1.0E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 Gene3D G3DSA:1.20.1250.20 10 221 2.2E-26 T 29-03-2018 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 SUPERFAMILY SSF103473 9 446 1.18E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 Gene3D G3DSA:1.20.1250.20 224 454 2.8E-13 T 29-03-2018 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 152 164 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 Pfam PF00854 POT family 244 422 1.9E-32 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 Pfam PF00854 POT family 88 211 3.1E-26 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 240 454 2.6E-43 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CWR56_RS11215 424b70b33c34ffc9142a0f06feed236e 463 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 12 224 1.6E-51 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 Pfam PF13412 Winged helix-turn-helix DNA-binding 13 53 2.3E-5 T 29-03-2018 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 Gene3D G3DSA:3.30.420.40 196 376 3.7E-34 T 29-03-2018 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 Gene3D G3DSA:1.10.10.10 6 76 7.6E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 SUPERFAMILY SSF53067 82 199 1.09E-14 T 29-03-2018 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 SUPERFAMILY SSF46785 8 74 8.33E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 Gene3D G3DSA:3.30.420.40 77 195 1.1E-9 T 29-03-2018 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 SUPERFAMILY SSF53067 204 378 1.67E-38 T 29-03-2018 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 Pfam PF00480 ROK family 85 368 1.8E-46 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS15285 a41fe23ba8611b0a332967a48c6293ef 386 ProSitePatterns PS01125 ROK family signature. 211 238 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Gene3D G3DSA:2.70.150.10 11 238 2.8E-45 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 1.4E-16 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF81660 362 565 8.94E-40 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Pfam PF00122 E1-E2 ATPase 116 335 1.7E-41 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SMART SM00831 2 76 1.9E-17 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Gene3D G3DSA:3.40.1110.10 320 560 3.5E-43 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Gene3D G3DSA:1.20.1110.10 562 912 2.7E-78 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF81653 115 235 1.7E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Pfam PF00702 haloacid dehalogenase-like hydrolase 353 669 1.6E-17 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 198 908 7.1E-159 T 29-03-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 281 382 5.3E-21 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 626 735 1.6E-32 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 674 2.1E-35 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 585 2.1E-35 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 564 2.1E-35 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 356 370 2.1E-35 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 691 2.1E-35 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 2.1E-35 T 29-03-2018 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 Pfam PF00689 Cation transporting ATPase, C-terminus 740 908 1.5E-35 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF81665 2 114 4.32E-104 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF81665 237 350 4.32E-104 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF81665 705 913 4.32E-104 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF56784 354 374 3.81E-53 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 SUPERFAMILY SSF56784 494 760 3.81E-53 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14385 a2200c4376209d0354591b2b05607c66 924 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 358 364 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Gene3D G3DSA:1.10.1780.10 1 156 3.8E-30 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Gene3D G3DSA:1.10.8.60 348 554 2.8E-42 T 29-03-2018 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Gene3D G3DSA:1.10.8.60 772 864 2.0E-23 T 29-03-2018 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 SMART SM01086 772 861 1.5E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 SMART SM00382 604 773 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 SMART SM00382 203 349 1.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 309 5.9E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 SUPERFAMILY SSF81923 4 161 1.31E-36 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Pfam PF07724 AAA domain (Cdc48 subfamily) 603 766 1.2E-54 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 851 7.1E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 860 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Gene3D G3DSA:3.40.50.300 559 771 3.0E-53 T 29-03-2018 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 SUPERFAMILY SSF52540 553 856 1.35E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 SUPERFAMILY SSF52540 162 552 4.39E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Gene3D G3DSA:3.40.50.300 162 347 7.1E-25 T 29-03-2018 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 638 656 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 64 9.1E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 4.8E-8 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 715 729 3.2E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 608 626 3.2E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 682 700 3.2E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS09650 f623a7c927e6441bf3b43874ccade34d 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 671 3.2E-41 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 683 1036 4.58E-35 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 207 251 3.9E-7 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 242 252 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Gene3D G3DSA:2.130.10.30 1318 1576 2.7E-37 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Gene3D G3DSA:2.130.10.30 185 382 4.7E-35 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 235 369 2.88E-26 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 416 452 2.88E-26 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Gene3D G3DSA:2.130.10.30 383 673 1.2E-16 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Gene3D G3DSA:2.130.10.30 28 184 3.2E-37 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Gene3D G3DSA:2.130.10.30 1125 1317 6.3E-8 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 637 673 3.92E-12 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 419 610 3.92E-12 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 1329 1482 2.7E-40 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 1122 1270 2.7E-40 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 SUPERFAMILY SSF50985 36 267 6.37E-49 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 85 114 4.5E-7 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 338 364 6.2E-5 T 29-03-2018 CWR56_RS06405 4c4a469eeb6297da43dc471ceeb732a8 1773 Gene3D G3DSA:2.130.10.30 747 1124 1.7E-45 T 29-03-2018 CWR56_RS15135 cb3397771853da3193cdc1a5141555ea 451 Gene3D G3DSA:1.20.1250.20 12 206 9.3E-20 T 29-03-2018 CWR56_RS15135 cb3397771853da3193cdc1a5141555ea 451 Pfam PF07690 Major Facilitator Superfamily 29 403 6.3E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS15135 cb3397771853da3193cdc1a5141555ea 451 SUPERFAMILY SSF103473 29 439 2.62E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS15135 cb3397771853da3193cdc1a5141555ea 451 Gene3D G3DSA:1.20.1250.20 218 451 1.7E-14 T 29-03-2018 CWR56_RS04280 179f22c83221862f947cf1e94d5b92fd 358 SMART SM00382 23 209 2.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04280 179f22c83221862f947cf1e94d5b92fd 358 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04280 179f22c83221862f947cf1e94d5b92fd 358 SUPERFAMILY SSF52540 8 239 3.34E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04280 179f22c83221862f947cf1e94d5b92fd 358 Pfam PF00005 ABC transporter 24 160 2.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04280 179f22c83221862f947cf1e94d5b92fd 358 Gene3D G3DSA:3.40.50.300 15 253 3.2E-55 T 29-03-2018 CWR56_RS17095 9e8f828ef78f004c272c9aa002dfccf2 295 Pfam PF00288 GHMP kinases N terminal domain 75 122 8.0E-8 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR56_RS17095 9e8f828ef78f004c272c9aa002dfccf2 295 PIRSF PIRSF033887 1 284 1.2E-67 T 29-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 CWR56_RS17095 9e8f828ef78f004c272c9aa002dfccf2 295 Pfam PF08544 GHMP kinases C terminal 193 269 2.8E-6 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS17095 9e8f828ef78f004c272c9aa002dfccf2 295 SUPERFAMILY SSF54211 3 144 6.68E-18 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS17095 9e8f828ef78f004c272c9aa002dfccf2 295 Gene3D G3DSA:3.30.230.10 34 141 3.3E-12 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS09905 2f16a65c6c311e6b76f49677c55bf16c 370 Gene3D G3DSA:1.10.443.10 172 360 2.2E-39 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS09905 2f16a65c6c311e6b76f49677c55bf16c 370 Pfam PF00589 Phage integrase family 171 352 5.2E-31 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS09905 2f16a65c6c311e6b76f49677c55bf16c 370 SUPERFAMILY SSF56349 62 359 9.42E-66 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS09905 2f16a65c6c311e6b76f49677c55bf16c 370 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 63 120 5.0E-14 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR56_RS09905 2f16a65c6c311e6b76f49677c55bf16c 370 Gene3D G3DSA:1.10.150.130 58 171 2.6E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS09905 2f16a65c6c311e6b76f49677c55bf16c 370 Pfam PF14657 Arm DNA-binding domain 19 53 2.3E-5 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 3.6E-19 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 1.8E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 1.8E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 1.8E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Gene3D G3DSA:3.40.120.10 1 161 4.4E-46 T 29-03-2018 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 SUPERFAMILY SSF53738 257 363 5.49E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 SUPERFAMILY SSF53738 2 180 1.77E-50 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 SUPERFAMILY SSF55957 357 447 3.53E-22 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 44.959 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Gene3D G3DSA:3.30.310.50 374 448 7.8E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 369 2.5E-31 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 1.3E-179 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Gene3D G3DSA:3.40.120.10 162 262 1.5E-29 T 29-03-2018 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Gene3D G3DSA:3.40.120.10 263 373 2.0E-30 T 29-03-2018 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 SUPERFAMILY SSF53738 157 256 2.63E-30 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 443 3.1E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS00565 b261fb46b7f98376f7a37b69484e4ebb 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 136 1.4E-46 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS08450 1da3475a074ba9b8d6f37ed79ca44f4d 300 Pfam PF04055 Radical SAM superfamily 30 197 4.7E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS08450 1da3475a074ba9b8d6f37ed79ca44f4d 300 SMART SM00729 29 251 0.0073 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS08450 1da3475a074ba9b8d6f37ed79ca44f4d 300 Gene3D G3DSA:3.20.20.70 7 297 3.3E-22 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS08450 1da3475a074ba9b8d6f37ed79ca44f4d 300 SUPERFAMILY SSF102114 23 225 2.35E-10 T 29-03-2018 CWR56_RS10035 2198a465ea615da4ff3a706b78407c70 448 Pfam PF00860 Permease family 22 396 2.9E-83 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS10035 2198a465ea615da4ff3a706b78407c70 448 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 428 3.2E-98 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR56_RS10035 2198a465ea615da4ff3a706b78407c70 448 TIGRFAM TIGR03173 pbuX: xanthine permease 25 429 8.6E-125 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CWR56_RS10035 2198a465ea615da4ff3a706b78407c70 448 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 345 365 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Gene3D G3DSA:3.40.50.720 2 126 1.3E-31 T 29-03-2018 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Gene3D G3DSA:3.40.50.261 127 295 6.0E-28 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Gene3D G3DSA:3.40.50.261 296 464 1.5E-20 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 SUPERFAMILY SSF56059 482 696 2.79E-44 T 29-03-2018 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Gene3D G3DSA:3.30.470.20 564 696 8.0E-28 T 29-03-2018 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Pfam PF13549 ATP-grasp domain 482 695 8.2E-63 T 29-03-2018 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 SUPERFAMILY SSF52210 132 290 4.84E-29 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Pfam PF13380 CoA binding domain 10 134 5.1E-19 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 SUPERFAMILY SSF51735 3 136 2.63E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 SMART SM00881 6 100 7.6E-26 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 158 291 2.8E-37 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 Gene3D G3DSA:3.30.1490.20 503 563 2.8E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS10600 9164c7870bfee3a9be3107738d75146b 699 SUPERFAMILY SSF52210 299 456 4.45E-19 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Gene3D G3DSA:3.40.50.20 2 84 1.2E-38 T 29-03-2018 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 SUPERFAMILY SSF52440 1 101 2.73E-36 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.3E-36 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 39.682 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 416 3.7E-29 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Gene3D G3DSA:3.30.1490.20 85 187 3.2E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 SUPERFAMILY SSF56059 102 322 5.13E-59 T 29-03-2018 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 SMART SM01209 101 293 3.1E-119 T 29-03-2018 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Gene3D G3DSA:3.90.600.10 327 416 4.5E-32 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 415 1.1E-161 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 SMART SM01210 327 416 3.3E-40 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 SUPERFAMILY SSF51246 326 415 4.0E-28 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Gene3D G3DSA:3.30.470.20 189 326 6.7E-52 T 29-03-2018 CWR56_RS01110 60fb148816c16eafc9cf580f9693c64f 416 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.5E-76 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS12855 e50f3a3521824a9c1dca689a57eac915 472 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 138 349 1.4E-27 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CWR56_RS12855 e50f3a3521824a9c1dca689a57eac915 472 PIRSF PIRSF500217 1 472 3.3E-132 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CWR56_RS12855 e50f3a3521824a9c1dca689a57eac915 472 PIRSF PIRSF016636 1 472 2.1E-130 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CWR56_RS12855 e50f3a3521824a9c1dca689a57eac915 472 Gene3D G3DSA:1.20.1250.20 1 361 2.2E-8 T 29-03-2018 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 SUPERFAMILY SSF74650 132 231 1.32E-35 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 SUPERFAMILY SSF74650 2 103 1.32E-35 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 Gene3D G3DSA:2.60.40.1180 613 674 7.5E-27 T 29-03-2018 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 SUPERFAMILY SSF51011 593 673 4.96E-22 T 29-03-2018 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 Gene3D G3DSA:2.60.40.1760 2 229 7.4E-40 T 29-03-2018 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 Gene3D G3DSA:3.20.20.80 230 612 4.0E-107 T 29-03-2018 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 Pfam PF01055 Glycosyl hydrolases family 31 226 675 4.8E-106 T 29-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CWR56_RS15310 792635c7c5b1d422d089353d4a4103f5 692 SUPERFAMILY SSF51445 233 592 2.2E-56 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS02200 c6951b5b80a5b9c5e0fc9d4b19297eef 234 TIGRFAM TIGR03740 galliderm_ABC: lantibiotic protection ABC transporter, ATP-binding subunit 6 227 5.1E-109 T 29-03-2018 IPR022501 Gallidermin ABC transporter, ATP-binding subunit CWR56_RS02200 c6951b5b80a5b9c5e0fc9d4b19297eef 234 SMART SM00382 30 206 2.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02200 c6951b5b80a5b9c5e0fc9d4b19297eef 234 SUPERFAMILY SSF52540 4 214 1.84E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02200 c6951b5b80a5b9c5e0fc9d4b19297eef 234 Gene3D G3DSA:3.40.50.300 2 220 8.6E-60 T 29-03-2018 CWR56_RS02200 c6951b5b80a5b9c5e0fc9d4b19297eef 234 Pfam PF00005 ABC transporter 21 158 4.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS15270 b0ccbd9c83f3c392942c67a7ea69c9e4 404 Gene3D G3DSA:3.30.750.44 32 130 2.0E-17 T 29-03-2018 CWR56_RS15270 b0ccbd9c83f3c392942c67a7ea69c9e4 404 Gene3D G3DSA:3.90.226.10 131 402 1.2E-33 T 29-03-2018 CWR56_RS15270 b0ccbd9c83f3c392942c67a7ea69c9e4 404 SUPERFAMILY SSF52096 294 380 1.99E-38 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS15270 b0ccbd9c83f3c392942c67a7ea69c9e4 404 SUPERFAMILY SSF52096 41 252 1.99E-38 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS15270 b0ccbd9c83f3c392942c67a7ea69c9e4 404 Pfam PF14684 Tricorn protease C1 domain 37 106 2.7E-7 T 29-03-2018 IPR028204 Tricorn protease C1 domain CWR56_RS15270 b0ccbd9c83f3c392942c67a7ea69c9e4 404 Pfam PF03572 Peptidase family S41 167 373 2.1E-27 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 SUPERFAMILY SSF55785 183 290 8.95E-14 T 29-03-2018 IPR000014 PAS domain CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 SMART SM00382 341 486 8.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 SUPERFAMILY SSF159800 3 185 1.16E-46 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Pfam PF02954 Bacterial regulatory protein, Fis family 586 625 4.0E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Gene3D G3DSA:3.40.50.300 314 493 1.1E-22 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 197 263 4.0E-8 T 29-03-2018 IPR000014 PAS domain CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Pfam PF00158 Sigma-54 interaction domain 321 488 4.5E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Pfam PF00989 PAS fold 196 263 5.2E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 SMART SM00091 194 260 7.3E-4 T 29-03-2018 IPR000014 PAS domain CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Gene3D G3DSA:3.30.450.20 168 298 7.1E-12 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Gene3D G3DSA:3.40.50.2300 1 86 1.4E-16 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 408 423 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Gene3D G3DSA:1.10.10.60 588 624 1.4E-9 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 345 358 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Gene3D G3DSA:1.10.8.60 494 587 3.0E-15 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Gene3D G3DSA:3.40.50.10660 87 166 3.0E-20 T 29-03-2018 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 Pfam PF06506 Propionate catabolism activator 26 189 4.4E-47 T 29-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 SUPERFAMILY SSF52540 320 563 6.12E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14580 94b1d7d8f27c3d97e9e9ce7de9645b81 630 SUPERFAMILY SSF46689 536 625 6.72E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09425 d48b90cd57b623b5e51ba35a637060c6 245 Pfam PF00005 ABC transporter 31 162 2.5E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09425 d48b90cd57b623b5e51ba35a637060c6 245 SMART SM00382 40 212 1.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09425 d48b90cd57b623b5e51ba35a637060c6 245 SUPERFAMILY SSF52540 16 215 1.43E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09425 d48b90cd57b623b5e51ba35a637060c6 245 Gene3D G3DSA:3.40.50.300 2 240 3.9E-54 T 29-03-2018 CWR56_RS09425 d48b90cd57b623b5e51ba35a637060c6 245 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS17880 d05c1ced99672da87466c7736e245042 247 Pfam PF13739 Domain of unknown function (DUF4163) 25 113 3.1E-7 T 29-03-2018 IPR025303 Deacetylase PdaC CWR56_RS17880 d05c1ced99672da87466c7736e245042 247 Gene3D G3DSA:3.30.565.40 3 141 6.7E-10 T 29-03-2018 CWR56_RS17880 d05c1ced99672da87466c7736e245042 247 Pfam PF11738 Protein of unknown function (DUF3298) 144 217 6.2E-16 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS17880 d05c1ced99672da87466c7736e245042 247 Gene3D G3DSA:3.90.640.20 142 229 2.6E-16 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 PIRSF PIRSF002122 3 156 7.2E-58 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.042 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 SUPERFAMILY SSF47973 3 152 7.98E-60 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.6E-68 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 Gene3D G3DSA:1.10.455.10 6 156 2.0E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CWR56_RS00065 6209871b2c6e314feffa37bdb995a2a0 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 6.5E-66 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 SUPERFAMILY SSF54862 1 168 4.19E-40 T 29-03-2018 CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 Pfam PF13247 4Fe-4S dicluster domain 55 152 4.3E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 Gene3D G3DSA:3.30.70.20 20 62 1.2E-7 T 29-03-2018 CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 Gene3D G3DSA:3.30.70.20 93 169 1.0E-15 T 29-03-2018 CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 Gene3D G3DSA:3.30.70.20 1 19 0.011 T 29-03-2018 CWR56_RS16660 244e88c922d947b414d7a575f6e8d3ee 171 Gene3D G3DSA:3.30.70.20 63 92 2.2E-9 T 29-03-2018 CWR56_RS09080 40119a25a97f6c7af5b815e6c5863c54 454 Gene3D G3DSA:1.10.220.70 56 140 2.3E-35 T 29-03-2018 CWR56_RS09080 40119a25a97f6c7af5b815e6c5863c54 454 PIRSF PIRSF018788 1 454 1.1E-244 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CWR56_RS09080 40119a25a97f6c7af5b815e6c5863c54 454 Gene3D G3DSA:3.20.20.70 143 449 7.2E-157 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS09080 40119a25a97f6c7af5b815e6c5863c54 454 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 8.5E-218 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CWR56_RS09080 40119a25a97f6c7af5b815e6c5863c54 454 Gene3D G3DSA:2.30.170.30 1 53 7.2E-25 T 29-03-2018 CWR56_RS04885 982f298893d99a7de9249f90b02a47a4 75 Gene3D G3DSA:1.10.1200.10 1 75 1.3E-26 T 29-03-2018 CWR56_RS04885 982f298893d99a7de9249f90b02a47a4 75 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 74 3.0E-11 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR56_RS04885 982f298893d99a7de9249f90b02a47a4 75 Hamap MF_01217 Acyl carrier protein [acpP]. 1 75 19.498 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR56_RS04885 982f298893d99a7de9249f90b02a47a4 75 SUPERFAMILY SSF47336 2 74 3.01E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR56_RS04885 982f298893d99a7de9249f90b02a47a4 75 Pfam PF00550 Phosphopantetheine attachment site 3 71 2.9E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR56_RS04885 982f298893d99a7de9249f90b02a47a4 75 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 75 1.8E-28 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 2.0E-34 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 347 358 2.0E-34 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 2.0E-34 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 93 107 2.0E-34 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 419 2.1E-69 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 Gene3D G3DSA:3.40.50.10860 34 169 1.0E-52 T 29-03-2018 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 101 114 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 SUPERFAMILY SSF51735 182 421 1.0E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 Gene3D G3DSA:3.40.50.720 182 421 9.6E-73 T 29-03-2018 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 PIRSF PIRSF000185 4 421 2.7E-157 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 SUPERFAMILY SSF53223 7 184 1.25E-69 T 29-03-2018 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 SMART SM00839 184 419 1.4E-89 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00885 91f4c8228dfc9100583fab4029af9684 421 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 36 163 1.4E-54 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 Gene3D G3DSA:3.40.250.10 14 145 1.3E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 Pfam PF00581 Rhodanese-like domain 23 130 5.8E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 Pfam PF00581 Rhodanese-like domain 296 419 1.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 Pfam PF00581 Rhodanese-like domain 171 264 1.1E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 SMART SM00450 295 423 1.7E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 SMART SM00450 151 268 1.5E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 SMART SM00450 20 135 3.7E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 SUPERFAMILY SSF52821 19 139 2.75E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 SUPERFAMILY SSF52821 289 420 4.58E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 Gene3D G3DSA:3.40.250.10 152 286 1.3E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 SUPERFAMILY SSF52821 166 270 2.36E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS00575 625415c15ca63ba09214854bfdbe3cfc 431 Gene3D G3DSA:3.40.250.10 289 430 3.7E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS14635 80422a7c47fbcc366912fa83565b95d8 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 100 8.1E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS14635 80422a7c47fbcc366912fa83565b95d8 105 SUPERFAMILY SSF46973 2 101 1.83E-36 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS14635 80422a7c47fbcc366912fa83565b95d8 105 Gene3D G3DSA:1.20.58.80 3 101 1.0E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS14635 80422a7c47fbcc366912fa83565b95d8 105 PIRSF PIRSF000699 1 105 1.2E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 Gene3D G3DSA:1.10.10.10 24 117 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 SUPERFAMILY SSF46785 7 142 4.85E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 6.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 6.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 6.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 6.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 SMART SM00347 26 126 1.3E-26 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10685 b75de2c9cc1bbdefdef8c283825970fc 153 Pfam PF01047 MarR family 34 90 8.4E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 SMART SM00448 1 113 1.3E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Gene3D G3DSA:3.40.50.2300 1 114 5.0E-29 T 29-03-2018 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 347 356 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Gene3D G3DSA:1.10.8.60 306 396 2.4E-20 T 29-03-2018 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Pfam PF02954 Bacterial regulatory protein, Fis family 397 437 5.3E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 158 171 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 SUPERFAMILY SSF46689 348 439 6.72E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Gene3D G3DSA:1.10.10.60 397 440 4.6E-15 T 29-03-2018 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 SUPERFAMILY SSF52172 1 178 7.12E-35 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Gene3D G3DSA:3.40.50.300 115 305 5.2E-23 T 29-03-2018 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Pfam PF00072 Response regulator receiver domain 3 113 6.4E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 SUPERFAMILY SSF52540 143 375 5.45E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 SMART SM00382 154 306 2.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 Pfam PF00158 Sigma-54 interaction domain 137 300 2.7E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS08340 fd49ee175b710489dd782a58e4ed2410 440 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 220 235 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 SUPERFAMILY SSF102114 2 308 2.22E-67 T 29-03-2018 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 SMART SM00729 10 211 5.5E-10 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 301 7.4E-33 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 1 319 1.2E-103 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 Gene3D G3DSA:3.20.20.70 1 319 5.2E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 Pfam PF13353 4Fe-4S single cluster domain 17 96 5.7E-9 T 29-03-2018 CWR56_RS08200 05d6a0445ecbd2160a319c2afbb8e2cd 319 Pfam PF04055 Radical SAM superfamily 15 174 4.1E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS14705 9b538c31d8f0816805d6288c94345b21 105 SUPERFAMILY SSF159468 4 102 2.75E-23 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14705 9b538c31d8f0816805d6288c94345b21 105 Pfam PF01990 ATP synthase (F/14-kDa) subunit 4 91 1.2E-20 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14705 9b538c31d8f0816805d6288c94345b21 105 Gene3D G3DSA:3.40.50.10580 1 105 5.0E-23 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS10080 65b78122f3cb276e1ffc5aee8288e1da 149 SUPERFAMILY SSF54292 3 77 7.6E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS10080 65b78122f3cb276e1ffc5aee8288e1da 149 Pfam PF01799 [2Fe-2S] binding domain 72 143 1.0E-22 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS10080 65b78122f3cb276e1ffc5aee8288e1da 149 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 60 1.9E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS10080 65b78122f3cb276e1ffc5aee8288e1da 149 Gene3D G3DSA:3.10.20.30 2 73 1.2E-18 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS10080 65b78122f3cb276e1ffc5aee8288e1da 149 Gene3D G3DSA:1.10.150.120 74 149 3.4E-23 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS10080 65b78122f3cb276e1ffc5aee8288e1da 149 SUPERFAMILY SSF47741 72 147 4.58E-24 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS09735 14f388eb4f87e5b02ff362c5148810b6 463 Gene3D G3DSA:3.75.10.10 1 363 4.6E-55 T 29-03-2018 CWR56_RS09735 14f388eb4f87e5b02ff362c5148810b6 463 SUPERFAMILY SSF55909 2 353 1.05E-51 T 29-03-2018 CWR56_RS09735 14f388eb4f87e5b02ff362c5148810b6 463 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 5 317 3.9E-26 T 29-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CWR56_RS09270 bc81fc1171c6b29f4c6ff9a29ebd8ff6 228 SUPERFAMILY SSF52540 10 228 1.09E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09270 bc81fc1171c6b29f4c6ff9a29ebd8ff6 228 Gene3D G3DSA:3.40.50.300 6 228 9.3E-66 T 29-03-2018 CWR56_RS09270 bc81fc1171c6b29f4c6ff9a29ebd8ff6 228 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS09270 bc81fc1171c6b29f4c6ff9a29ebd8ff6 228 SMART SM00382 38 226 3.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09270 bc81fc1171c6b29f4c6ff9a29ebd8ff6 228 Pfam PF00005 ABC transporter 29 177 2.2E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 Pfam PF01381 Helix-turn-helix 13 62 4.0E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 SUPERFAMILY SSF51182 50 182 7.83E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 Gene3D G3DSA:1.10.260.40 7 79 6.1E-17 T 29-03-2018 CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 Gene3D G3DSA:2.60.120.10 80 180 1.7E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 SMART SM00530 10 65 5.0E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 SUPERFAMILY SSF47413 3 70 9.65E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS07935 133d11c35f11697bdbb7cfc5136b6ede 183 Pfam PF07883 Cupin domain 110 178 2.1E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 Pfam PF00563 EAL domain 458 683 8.6E-58 T 29-03-2018 IPR001633 EAL domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 SUPERFAMILY SSF141868 458 693 2.22E-77 T 29-03-2018 IPR001633 EAL domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 SUPERFAMILY SSF55785 161 267 2.44E-11 T 29-03-2018 IPR000014 PAS domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 SMART SM00052 441 688 1.2E-73 T 29-03-2018 IPR001633 EAL domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 SMART SM00267 262 431 2.6E-17 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 Pfam PF08447 PAS fold 181 266 6.3E-13 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 Gene3D G3DSA:3.30.450.20 132 273 5.7E-13 T 29-03-2018 CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 SUPERFAMILY SSF55073 278 433 1.49E-30 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 271 429 4.6E-24 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 Gene3D G3DSA:3.20.20.450 438 690 2.1E-76 T 29-03-2018 IPR001633 EAL domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 Pfam PF00990 Diguanylate cyclase, GGDEF domain 274 427 2.0E-25 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07165 42da193b829e9455d0ccc1b37e991446 697 Gene3D G3DSA:3.30.70.270 274 437 9.5E-35 T 29-03-2018 CWR56_RS10820 5ad5ec57a34abf7528f83bf5c1dbe008 295 Gene3D G3DSA:3.30.420.40 122 295 2.3E-43 T 29-03-2018 CWR56_RS10820 5ad5ec57a34abf7528f83bf5c1dbe008 295 SUPERFAMILY SSF53067 3 292 2.69E-55 T 29-03-2018 CWR56_RS10820 5ad5ec57a34abf7528f83bf5c1dbe008 295 Pfam PF00480 ROK family 4 289 3.5E-52 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS10820 5ad5ec57a34abf7528f83bf5c1dbe008 295 Gene3D G3DSA:3.30.420.40 2 121 1.5E-22 T 29-03-2018 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 118 250 8.8E-43 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 PIRSF PIRSF000161 1 251 1.2E-78 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 Gene3D G3DSA:3.30.360.10 131 220 1.2E-35 T 29-03-2018 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 251 2.9E-64 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 139 156 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 SUPERFAMILY SSF55347 117 221 1.85E-29 T 29-03-2018 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 114 1.9E-26 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 Gene3D G3DSA:3.40.50.720 1 130 1.9E-22 T 29-03-2018 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 251 29.421 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 SUPERFAMILY SSF51735 222 251 3.71E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16225 411539de47f24b80cbd19620fe201d6b 251 SUPERFAMILY SSF51735 1 116 3.71E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 10 241 2.1E-120 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 259 332 5.3E-33 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 29 332 4.6E-148 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 Gene3D G3DSA:1.10.8.60 190 260 1.0E-31 T 29-03-2018 CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 SUPERFAMILY SSF46785 262 336 1.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 Gene3D G3DSA:1.10.10.10 263 333 1.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 SUPERFAMILY SSF52540 26 256 6.69E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 SMART SM00382 57 190 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 339 173.778 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 256 335 3.0E-27 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CWR56_RS14235 679e90be3da23070818e0f7eac22b290 339 Gene3D G3DSA:3.40.50.300 24 187 4.6E-32 T 29-03-2018 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 SUPERFAMILY SSF52096 199 368 1.11E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 SUPERFAMILY SSF52096 42 128 1.11E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 SMART SM00228 109 180 6.6E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 61 374 8.2E-91 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 SUPERFAMILY SSF50156 106 202 7.59E-20 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 Gene3D G3DSA:3.30.750.44 19 110 9.8E-10 T 29-03-2018 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 Pfam PF03572 Peptidase family S41 205 364 6.6E-51 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 Gene3D G3DSA:3.90.226.10 188 385 8.6E-61 T 29-03-2018 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 Pfam PF13180 PDZ domain 118 188 1.7E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 SMART SM00245 169 366 3.9E-49 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CWR56_RS17220 af239f6d2742144d618111eb2412198e 385 Gene3D G3DSA:2.30.42.10 111 187 2.6E-19 T 29-03-2018 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 SUPERFAMILY SSF57802 1 49 2.36E-13 T 29-03-2018 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 Pfam PF01645 Conserved region in glutamate synthase 135 453 1.8E-98 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 Gene3D G3DSA:3.20.20.70 108 479 2.9E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 Gene3D G3DSA:2.20.28.10 1 45 8.4E-12 T 29-03-2018 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 PIRSF PIRSF500061 13 479 7.6E-134 T 29-03-2018 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 Pfam PF00301 Rubredoxin 4 41 1.2E-6 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 PIRSF PIRSF006429 25 480 7.7E-144 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein CWR56_RS04055 5845f6a72bcd623ed6be79f72284011a 480 SUPERFAMILY SSF51395 93 475 7.69E-97 T 29-03-2018 CWR56_RS12690 c84162f0af2bad240d4268f5727dd9e7 160 SUPERFAMILY SSF51261 3 158 2.27E-53 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS12690 c84162f0af2bad240d4268f5727dd9e7 160 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 75 87 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS12690 c84162f0af2bad240d4268f5727dd9e7 160 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 14 133 4.6E-42 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS12690 c84162f0af2bad240d4268f5727dd9e7 160 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 12 136 3.8E-48 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS12690 c84162f0af2bad240d4268f5727dd9e7 160 Gene3D G3DSA:2.70.70.10 3 160 5.7E-55 T 29-03-2018 CWR56_RS08455 ebd1c466512266bebef1cae059410a74 276 Pfam PF13649 Methyltransferase domain 71 164 9.7E-18 T 29-03-2018 CWR56_RS08455 ebd1c466512266bebef1cae059410a74 276 SUPERFAMILY SSF53335 47 276 4.82E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS08455 ebd1c466512266bebef1cae059410a74 276 Gene3D G3DSA:3.40.50.150 9 267 1.3E-26 T 29-03-2018 CWR56_RS15105 6ea2d4a656a0f24b87979ef3ef1a61fe 525 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 412 502 2.0E-17 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15105 6ea2d4a656a0f24b87979ef3ef1a61fe 525 Pfam PF00367 phosphotransferase system, EIIB 444 477 3.8E-12 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15105 6ea2d4a656a0f24b87979ef3ef1a61fe 525 Gene3D G3DSA:3.30.1360.60 441 516 1.4E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15105 6ea2d4a656a0f24b87979ef3ef1a61fe 525 Pfam PF02378 Phosphotransferase system, EIIC 16 353 1.0E-67 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15105 6ea2d4a656a0f24b87979ef3ef1a61fe 525 SUPERFAMILY SSF55604 444 516 4.71E-18 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15105 6ea2d4a656a0f24b87979ef3ef1a61fe 525 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 455 472 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 32 673 3.4E-124 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 SUPERFAMILY SSF52540 27 200 1.71E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 Gene3D G3DSA:3.40.50.300 18 312 5.8E-34 T 29-03-2018 CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 Pfam PF07664 Ferrous iron transport protein B C terminus 494 541 9.6E-13 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 Pfam PF07670 Nucleoside recognition 553 676 3.4E-18 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 Pfam PF07670 Nucleoside recognition 380 470 7.1E-6 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS07180 cf5c86a36697709c9d85d918fca44b72 706 Pfam PF02421 Ferrous iron transport protein B 27 180 3.3E-59 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 Gene3D G3DSA:3.40.605.10 2 242 4.7E-27 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 Gene3D G3DSA:1.20.1090.10 661 880 6.3E-65 T 29-03-2018 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 SUPERFAMILY SSF53720 24 469 1.07E-79 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 649 677 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 Gene3D G3DSA:3.40.50.1970 446 660 1.2E-51 T 29-03-2018 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 Gene3D G3DSA:3.40.309.10 243 419 5.7E-28 T 29-03-2018 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 Pfam PF00465 Iron-containing alcohol dehydrogenase 473 864 1.4E-115 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 PIRSF PIRSF000111 11 880 0.0 T 29-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 SUPERFAMILY SSF56796 464 879 1.7E-122 T 29-03-2018 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 Pfam PF00171 Aldehyde dehydrogenase family 33 416 7.4E-23 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS01745 88562ee18b33ef7e6282346a6a994b5a 880 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 737 757 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWR56_RS04075 af2591fe65cd17144bd67cc9618ece6e 397 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04075 af2591fe65cd17144bd67cc9618ece6e 397 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR56_RS04075 af2591fe65cd17144bd67cc9618ece6e 397 Pfam PF00682 HMGL-like 12 269 7.6E-77 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWR56_RS04075 af2591fe65cd17144bd67cc9618ece6e 397 TIGRFAM TIGR02660 nifV_homocitr: homocitrate synthase 12 376 8.1E-155 T 29-03-2018 IPR013477 Homocitrate synthase NifV-type GO:0004410|GO:0051188 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 CWR56_RS04075 af2591fe65cd17144bd67cc9618ece6e 397 Gene3D G3DSA:3.20.20.70 3 333 6.6E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS04075 af2591fe65cd17144bd67cc9618ece6e 397 SUPERFAMILY SSF51569 8 288 7.33E-85 T 29-03-2018 CWR56_RS18040 0b5532f5d81628213201eb5180a17255 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 13 423 5.9E-72 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS18040 0b5532f5d81628213201eb5180a17255 452 PIRSF PIRSF006603 2 452 1.3E-89 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS18040 0b5532f5d81628213201eb5180a17255 452 Pfam PF01554 MatE 249 410 9.3E-25 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS18040 0b5532f5d81628213201eb5180a17255 452 Pfam PF01554 MatE 13 175 7.3E-36 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS10495 5d9395427e9a0b81e790e09d12c329b1 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 112 1.1E-23 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWR56_RS10495 5d9395427e9a0b81e790e09d12c329b1 220 SUPERFAMILY SSF161098 13 209 6.28E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS10495 5d9395427e9a0b81e790e09d12c329b1 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 218 2.0E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS10495 5d9395427e9a0b81e790e09d12c329b1 220 Gene3D G3DSA:1.10.3720.10 2 220 2.7E-42 T 29-03-2018 CWR56_RS15870 7d1e0726456b80abed6087610e6c3bac 290 SUPERFAMILY SSF52540 5 219 2.87E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15870 7d1e0726456b80abed6087610e6c3bac 290 Gene3D G3DSA:3.40.50.300 1 244 3.3E-62 T 29-03-2018 CWR56_RS15870 7d1e0726456b80abed6087610e6c3bac 290 Pfam PF00005 ABC transporter 20 162 6.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS15870 7d1e0726456b80abed6087610e6c3bac 290 SMART SM00382 28 208 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SMART SM01096 420 543 2.7E-56 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 869 1.2E-37 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.7E-76 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 543 9.0E-36 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SUPERFAMILY SSF56059 128 399 7.78E-102 T 29-03-2018 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:3.30.470.20 741 931 4.3E-36 T 29-03-2018 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:3.30.1490.20 651 740 5.6E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1061 12.804 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SMART SM00851 953 1040 1.6E-25 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:3.40.50.1380 932 1068 2.1E-34 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:1.10.1030.10 402 534 3.3E-45 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SUPERFAMILY SSF52440 553 671 2.16E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SUPERFAMILY SSF52440 1 127 1.24E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:3.30.470.20 119 401 8.1E-60 T 29-03-2018 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1050 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 4.0E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SUPERFAMILY SSF56059 669 930 5.83E-96 T 29-03-2018 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SUPERFAMILY SSF48108 395 549 6.67E-44 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 SUPERFAMILY SSF52335 940 1058 4.32E-31 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:3.40.50.20 535 650 1.2E-58 T 29-03-2018 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Pfam PF02142 MGS-like domain 954 1035 1.8E-20 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Gene3D G3DSA:3.40.50.20 5 117 8.1E-38 T 29-03-2018 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1066 13.271 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17930 db8c6b6ca5423e6db3e2a4f45a0a8f95 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 154 425 61.307 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 398 411 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 Gene3D G3DSA:1.20.120.140 117 213 2.5E-22 T 29-03-2018 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 SMART SM00382 223 403 3.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 Pfam PF00448 SRP54-type protein, GTPase domain 225 424 9.3E-79 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 154 424 3.1E-108 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 SMART SM00963 130 211 1.4E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 SMART SM00962 224 425 3.4E-115 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 Gene3D G3DSA:3.40.50.300 217 426 8.6E-44 T 29-03-2018 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 SUPERFAMILY SSF52540 222 425 1.1E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 SUPERFAMILY SSF47364 125 204 1.57E-20 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05780 4e2fae7bede61d22be1ddd2b85ac6d00 426 Pfam PF02881 SRP54-type protein, helical bundle domain 142 211 2.8E-14 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS09070 e17936b8cf1b160e45b96b900191a4b5 469 Gene3D G3DSA:3.30.565.10 329 468 5.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09070 e17936b8cf1b160e45b96b900191a4b5 469 Gene3D G3DSA:3.30.450.20 159 315 0.084 T 29-03-2018 CWR56_RS09070 e17936b8cf1b160e45b96b900191a4b5 469 Pfam PF07568 Histidine kinase 276 347 5.0E-15 T 29-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CWR56_RS09070 e17936b8cf1b160e45b96b900191a4b5 469 SUPERFAMILY SSF55874 354 465 4.71E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09070 e17936b8cf1b160e45b96b900191a4b5 469 Pfam PF12282 Signal transduction histidine kinase 6 140 2.5E-24 T 29-03-2018 IPR022066 Signal transduction histidine kinase CWR56_RS08380 27391027dd863760b5ca05ff90c9a977 417 Pfam PF03616 Sodium/glutamate symporter 5 384 2.8E-100 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CWR56_RS08380 27391027dd863760b5ca05ff90c9a977 417 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 4 416 21.835 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 PRINTS PR00045 Sigma-54 factor signature 160 177 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 PRINTS PR00045 Sigma-54 factor signature 364 375 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 PRINTS PR00045 Sigma-54 factor signature 422 440 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 PRINTS PR00045 Sigma-54 factor signature 348 360 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 427 434 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 Gene3D G3DSA:1.10.10.10 294 386 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 Pfam PF04963 Sigma-54 factor, core binding domain 87 274 2.5E-51 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 51 2.3E-15 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 PIRSF PIRSF000774 1 448 1.0E-139 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 Pfam PF04552 Sigma-54, DNA binding domain 289 446 6.3E-63 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 446 3.3E-135 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15945 e7b2ebd303e8e8c6381ed690c3bb016b 448 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 336 355 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 Pfam PF04055 Radical SAM superfamily 111 270 6.4E-21 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 343 71.645 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 341 5.7E-126 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 PIRSF PIRSF006004 2 343 1.5E-127 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 SMART SM00729 102 310 0.0043 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 Gene3D G3DSA:3.20.20.70 14 328 4.7E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 Pfam PF13394 4Fe-4S single cluster domain 113 198 1.2E-5 T 29-03-2018 CWR56_RS13045 e333b69974501f74c91b611556ed02c0 343 SUPERFAMILY SSF102114 101 295 1.83E-14 T 29-03-2018 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 181 305 1.1E-34 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 Pfam PF02558 Ketopantoate reductase PanE/ApbA 13 154 5.0E-18 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 Gene3D G3DSA:3.40.50.720 2 180 9.9E-16 T 29-03-2018 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 SUPERFAMILY SSF48179 181 306 6.46E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 11 306 8.2E-60 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 Gene3D G3DSA:1.10.1040.10 181 308 6.2E-37 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR56_RS00935 71e9a26eba3d18c7cb841c0d0588a805 308 SUPERFAMILY SSF51735 10 128 3.43E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS05340 0326474043bcdde700f04b554d97f2cd 426 Hamap MF_01539 UPF0348 protein . 2 424 37.74 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CWR56_RS05340 0326474043bcdde700f04b554d97f2cd 426 Gene3D G3DSA:3.40.50.620 1 257 1.6E-59 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS05340 0326474043bcdde700f04b554d97f2cd 426 SUPERFAMILY SSF52374 169 248 5.85E-16 T 29-03-2018 CWR56_RS05340 0326474043bcdde700f04b554d97f2cd 426 SUPERFAMILY SSF52374 4 107 5.85E-16 T 29-03-2018 CWR56_RS05340 0326474043bcdde700f04b554d97f2cd 426 Pfam PF05636 HIGH Nucleotidyl Transferase 1 409 3.4E-142 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 SMART SM00876 240 333 0.0045 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 SMART SM00729 64 275 5.2E-19 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 PIRSF PIRSF004762 1 346 9.3E-71 T 29-03-2018 CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 SUPERFAMILY SSF102114 30 307 9.42E-52 T 29-03-2018 CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 10 354 1.4E-162 T 29-03-2018 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 Gene3D G3DSA:3.20.20.70 1 355 2.2E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10385 d13ce4f90f9ca71b49ff3eb82c21b5ea 361 Pfam PF04055 Radical SAM superfamily 68 226 9.4E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 3.3E-190 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 SUPERFAMILY SSF47446 328 428 1.96E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 SUPERFAMILY SSF52540 43 354 2.66E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 SMART SM00963 2 87 2.3E-35 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 SMART SM00382 100 301 1.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Gene3D G3DSA:1.10.260.30 328 431 4.8E-39 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Gene3D G3DSA:3.40.50.300 93 297 2.3E-41 T 29-03-2018 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.6E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Pfam PF02978 Signal peptide binding domain 328 427 3.2E-35 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Gene3D G3DSA:1.20.120.140 1 92 3.6E-29 T 29-03-2018 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 1.0E-79 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 447 35.07 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CWR56_RS05790 71aac79d72938d4e1c8c029f6f6bbb63 450 SMART SM00962 101 296 3.7E-121 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS05610 261ebd660024ce92d1a7026f733dbc84 224 SUPERFAMILY SSF53335 32 214 3.95E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS05610 261ebd660024ce92d1a7026f733dbc84 224 Gene3D G3DSA:3.40.50.150 6 215 2.3E-39 T 29-03-2018 CWR56_RS05610 261ebd660024ce92d1a7026f733dbc84 224 Pfam PF01596 O-methyltransferase 39 213 8.6E-33 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 SUPERFAMILY SSF50494 55 263 8.98E-59 T 29-03-2018 IPR009003 Peptidase S1, PA clan CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 SMART SM00228 267 350 1.5E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 Gene3D G3DSA:2.40.10.10 52 159 4.6E-29 T 29-03-2018 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 Gene3D G3DSA:2.40.10.10 160 257 3.0E-39 T 29-03-2018 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 SUPERFAMILY SSF50156 248 358 8.05E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 PRINTS PR00834 HtrA/DegQ protease family signature 101 113 1.6E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 PRINTS PR00834 HtrA/DegQ protease family signature 202 219 1.6E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 PRINTS PR00834 HtrA/DegQ protease family signature 124 144 1.6E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 PRINTS PR00834 HtrA/DegQ protease family signature 164 188 1.6E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 PRINTS PR00834 HtrA/DegQ protease family signature 224 241 1.6E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 PRINTS PR00834 HtrA/DegQ protease family signature 308 320 1.6E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 Pfam PF13365 Trypsin-like peptidase domain 92 231 2.9E-34 T 29-03-2018 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 Pfam PF13180 PDZ domain 270 358 1.2E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS16515 862f77637cea94989ebe8695fbf46659 359 Gene3D G3DSA:2.30.42.10 265 359 7.0E-21 T 29-03-2018 CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 Pfam PF07729 FCD domain 79 203 4.8E-11 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 4.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 Gene3D G3DSA:1.20.120.530 64 206 5.5E-15 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 SMART SM00895 78 205 0.0032 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 Gene3D G3DSA:1.10.10.10 3 63 1.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 SMART SM00345 10 68 5.3E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 SUPERFAMILY SSF48008 75 204 2.88E-12 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS04360 9554ef3dba9bf004eebda0c68802dd9d 217 SUPERFAMILY SSF46785 5 72 8.73E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17600 38a818a3d3280da9e4a7afc30aa61d0a 331 Pfam PF00005 ABC transporter 19 161 5.7E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS17600 38a818a3d3280da9e4a7afc30aa61d0a 331 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS17600 38a818a3d3280da9e4a7afc30aa61d0a 331 SUPERFAMILY SSF52540 3 240 1.43E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17600 38a818a3d3280da9e4a7afc30aa61d0a 331 SUPERFAMILY SSF50331 240 323 9.07E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWR56_RS17600 38a818a3d3280da9e4a7afc30aa61d0a 331 Gene3D G3DSA:3.40.50.300 1 272 1.8E-79 T 29-03-2018 CWR56_RS17600 38a818a3d3280da9e4a7afc30aa61d0a 331 SMART SM00382 28 211 4.6E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03515 e5ec6c66a3fb647991c757bd1b4b5489 455 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 65 443 8.3E-83 T 29-03-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel CWR56_RS03515 e5ec6c66a3fb647991c757bd1b4b5489 455 Gene3D G3DSA:3.20.20.20 59 319 8.3E-17 T 29-03-2018 CWR56_RS03515 e5ec6c66a3fb647991c757bd1b4b5489 455 PIRSF PIRSF000376 1 451 1.6E-126 T 29-03-2018 IPR016218 Acetyl-CoA decarbonylase/synthase complex, gamma subunit GO:0005506|GO:0008168|GO:0046356 CWR56_RS03515 e5ec6c66a3fb647991c757bd1b4b5489 455 Pfam PF04060 Putative Fe-S cluster 13 43 2.7E-11 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 Gene3D G3DSA:3.40.50.300 1034 1166 6.2E-11 T 29-03-2018 CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 Gene3D G3DSA:1.10.287.510 523 643 9.4E-6 T 29-03-2018 CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 Gene3D G3DSA:1.10.287.510 951 1022 0.17 T 29-03-2018 CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 SUPERFAMILY SSF52540 1066 1149 1.31E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 SUPERFAMILY SSF52540 26 224 1.31E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1059 1131 7.6E-13 T 29-03-2018 CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 Gene3D G3DSA:3.40.50.300 1 159 1.3E-23 T 29-03-2018 CWR56_RS04785 9bd9418e5a043a8a878a6c411317d551 1175 Pfam PF13476 AAA domain 5 206 4.0E-23 T 29-03-2018 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 3.0E-54 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 Gene3D G3DSA:4.10.910.10 68 86 1.7E-17 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 PIRSF PIRSF002134 1 123 2.8E-46 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 Gene3D G3DSA:4.10.910.10 87 122 3.1E-27 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 SUPERFAMILY SSF46946 2 121 3.79E-48 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 Gene3D G3DSA:1.10.8.50 1 67 4.2E-27 T 29-03-2018 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 Pfam PF00416 Ribosomal protein S13/S18 3 109 4.2E-33 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00215 f5277f491a3aa4eeeb03db12d612df11 123 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 29.61 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 SUPERFAMILY SSF63520 197 282 1.57E-9 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Gene3D G3DSA:1.10.10.10 89 157 3.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Gene3D G3DSA:1.10.10.10 1 67 1.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Pfam PF08279 HTH domain 4 61 7.3E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Pfam PF00874 PRD domain 206 282 4.1E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Pfam PF00874 PRD domain 304 393 2.6E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 SUPERFAMILY SSF63520 295 393 1.01E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 SUPERFAMILY SSF46785 2 63 2.51E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Pfam PF05043 Mga helix-turn-helix domain 95 166 1.6E-11 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Gene3D G3DSA:3.40.930.10 498 641 4.2E-25 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Gene3D G3DSA:3.40.50.2300 403 493 8.4E-16 T 29-03-2018 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Gene3D G3DSA:1.10.1790.10 284 398 2.0E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Gene3D G3DSA:1.10.1790.10 164 283 9.2E-8 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 502 640 3.6E-27 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 SUPERFAMILY SSF55804 498 640 1.02E-29 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 SUPERFAMILY SSF46785 92 148 5.88E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12970 b597d0792b5289fe116d951c9ecdda49 642 SUPERFAMILY SSF52794 404 487 1.73E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 Gene3D G3DSA:3.40.50.1820 133 475 3.3E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 161 695 2.2E-111 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 SMART SM00939 444 692 4.2E-62 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 SUPERFAMILY SSF53474 143 480 3.07E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 164 417 3.9E-56 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 Gene3D G3DSA:2.60.120.260 476 696 5.0E-44 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 SUPERFAMILY SSF49785 471 695 4.68E-41 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS06500 24f3b5aa266b69a204150e2014bb2d7b 698 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 456 691 3.1E-36 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CWR56_RS16785 d0102adcc06ad0be3841f1dcbc31d7b1 160 Pfam PF12833 Helix-turn-helix domain 29 106 9.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS16785 d0102adcc06ad0be3841f1dcbc31d7b1 160 SUPERFAMILY SSF46689 6 56 2.33E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16785 d0102adcc06ad0be3841f1dcbc31d7b1 160 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS16785 d0102adcc06ad0be3841f1dcbc31d7b1 160 SMART SM00342 22 105 1.0E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS16785 d0102adcc06ad0be3841f1dcbc31d7b1 160 SUPERFAMILY SSF46689 58 107 1.03E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16785 d0102adcc06ad0be3841f1dcbc31d7b1 160 Gene3D G3DSA:3.90.1240.10 1 158 7.2E-31 T 29-03-2018 CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 SMART SM00418 6 83 1.8E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 Pfam PF01022 Bacterial regulatory protein, arsR family 13 57 3.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 5.8E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 5.8E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 5.8E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 SUPERFAMILY SSF46785 1 96 5.11E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08090 b450d863cc9edf64b7ccfa494be9fc5d 122 Gene3D G3DSA:1.10.10.10 1 76 1.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14910 a78e9d38a5e015cb78dc1f0c390851b3 398 SMART SM00382 26 214 5.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14910 a78e9d38a5e015cb78dc1f0c390851b3 398 Pfam PF00005 ABC transporter 18 165 9.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS14910 a78e9d38a5e015cb78dc1f0c390851b3 398 ProDom PD064925 ATP-BINDING ABC NUCLEOTIDE-BINDING MEMBRANE TRANSPORTER IRON TRANSPORTER COMPOUND ATPASE III 286 367 9.0E-15 T 29-03-2018 IPR020322 Uncharacterised domain MJ0874 CWR56_RS14910 a78e9d38a5e015cb78dc1f0c390851b3 398 Gene3D G3DSA:3.40.50.300 1 252 8.9E-55 T 29-03-2018 CWR56_RS14910 a78e9d38a5e015cb78dc1f0c390851b3 398 SUPERFAMILY SSF52540 2 227 2.17E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 SUPERFAMILY SSF52141 2 221 8.29E-95 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 213 3.5E-82 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 SMART SM00986 49 209 4.9E-38 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 SMART SM00987 49 209 4.9E-38 T 29-03-2018 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 Pfam PF03167 Uracil DNA glycosylase superfamily 54 210 3.6E-26 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 Gene3D G3DSA:3.40.470.10 1 224 1.2E-101 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 5 220 40.753 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS12540 3df4114a6835c84ef524a733be9f0f09 224 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 SUPERFAMILY SSF52343 84 227 8.91E-23 T 29-03-2018 CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 Gene3D G3DSA:2.40.30.10 1 87 8.5E-10 T 29-03-2018 CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 PIRSF PIRSF006816 1 230 1.3E-59 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 Gene3D G3DSA:2.10.240.10 190 227 9.6E-17 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 Gene3D G3DSA:3.40.50.80 91 188 2.5E-5 T 29-03-2018 CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 190 226 2.8E-16 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWR56_RS00920 b8b3137615783eef26b547cbc3e52fce 230 SUPERFAMILY SSF63380 1 89 9.68E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 18 430 38.024 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 296 1.8E-56 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 SUPERFAMILY SSF50621 272 429 3.35E-49 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 397 419 6.6E-22 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 315 333 6.6E-22 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 80 97 6.6E-22 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 169 178 6.6E-22 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 429 4.5E-142 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 SUPERFAMILY SSF51419 29 298 8.64E-77 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 Gene3D G3DSA:3.20.20.10 37 282 3.8E-53 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 286 305 1.3E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 82 94 1.3E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 197 210 1.3E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 387 400 1.3E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 96 387 1.1E-13 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CWR56_RS09835 ec0897d46ede73ea13b304483cda62d1 430 Gene3D G3DSA:2.40.37.10 283 430 2.7E-38 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 Gene3D G3DSA:3.30.70.20 1 20 0.0029 T 29-03-2018 CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 Pfam PF00037 4Fe-4S binding domain 90 112 5.3E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 Gene3D G3DSA:3.30.70.20 21 77 4.4E-13 T 29-03-2018 CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 Gene3D G3DSA:3.30.70.20 78 130 1.7E-17 T 29-03-2018 CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 Pfam PF12800 4Fe-4S binding domain 13 26 0.11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 SUPERFAMILY SSF54862 1 169 2.3E-39 T 29-03-2018 CWR56_RS16670 7959c5e217df78815cabb2fc3a4ac302 183 Gene3D G3DSA:3.30.70.20 131 178 1.9E-4 T 29-03-2018 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 618 2.3E-239 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 SUPERFAMILY SSF52922 487 619 1.7E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Pfam PF02780 Transketolase, C-terminal domain 490 611 1.4E-30 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 SUPERFAMILY SSF52518 2 193 2.64E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 SUPERFAMILY SSF52518 242 377 2.64E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Gene3D G3DSA:3.40.50.920 490 620 3.0E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 SUPERFAMILY SSF52518 315 500 5.49E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 281 3.1E-118 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Gene3D G3DSA:3.40.50.970 297 485 1.3E-55 T 29-03-2018 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Gene3D G3DSA:3.40.50.970 1 296 3.5E-82 T 29-03-2018 CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 SMART SM00861 315 479 6.5E-57 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Pfam PF02779 Transketolase, pyrimidine binding domain 320 475 5.8E-33 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS05510 46fbcebdc69435af6feff08628354859 621 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 620 43.727 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 310 2.5E-126 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 SUPERFAMILY SSF53335 4 113 4.0E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 SUPERFAMILY SSF53335 215 311 4.0E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 311 40.224 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 Gene3D G3DSA:3.40.50.150 183 311 5.2E-21 T 29-03-2018 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 Gene3D G3DSA:3.40.50.150 5 182 5.0E-22 T 29-03-2018 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 PIRSF PIRSF004486 1 311 1.0E-120 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 SUPERFAMILY SSF81799 114 215 4.84E-36 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS13450 edb8708a079c77d6c7c70567b97d66b3 311 Pfam PF01795 MraW methylase family 2 311 7.2E-131 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 SUPERFAMILY SSF53335 4 279 1.28E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 305 366 1.5E-20 T 29-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 275 2.2E-44 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 Gene3D G3DSA:3.30.70.1170 23 88 1.4E-16 T 29-03-2018 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 388 434 1.5E-18 T 29-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 Gene3D G3DSA:3.40.50.150 89 288 9.3E-51 T 29-03-2018 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 108 118 2.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 79 93 2.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 241 2.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 175 187 2.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 262 279 2.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS02545 d051ff1aac19aeb701a3b19154ecb434 436 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 4 93 1.4E-30 T 29-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 55 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 SUPERFAMILY SSF46689 6 54 4.12E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 Gene3D G3DSA:3.20.80.10 142 303 2.4E-18 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 Pfam PF14526 Integron-associated effector binding protein 174 296 1.1E-8 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 Gene3D G3DSA:1.10.10.60 58 113 7.3E-14 T 29-03-2018 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 1.4E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 1.4E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 SUPERFAMILY SSF55136 148 296 5.75E-6 T 29-03-2018 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 SUPERFAMILY SSF46689 57 111 4.17E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 Gene3D G3DSA:1.10.10.60 3 57 2.7E-13 T 29-03-2018 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 Pfam PF12833 Helix-turn-helix domain 27 105 4.9E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS01415 2d7b4d4f3ba9b32371a5a639262e2e96 303 SMART SM00342 21 104 1.1E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 PIRSF PIRSF000676 1 296 2.4E-89 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 PRINTS PR00958 Homoserine kinase signature 124 137 2.1E-39 T 29-03-2018 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 PRINTS PR00958 Homoserine kinase signature 163 180 2.1E-39 T 29-03-2018 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 PRINTS PR00958 Homoserine kinase signature 242 257 2.1E-39 T 29-03-2018 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 PRINTS PR00958 Homoserine kinase signature 9 24 2.1E-39 T 29-03-2018 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 PRINTS PR00958 Homoserine kinase signature 90 105 2.1E-39 T 29-03-2018 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 SUPERFAMILY SSF55060 158 277 4.32E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 SUPERFAMILY SSF54211 2 148 1.37E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 TIGRFAM TIGR00191 thrB: homoserine kinase 2 292 1.2E-84 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 Pfam PF00288 GHMP kinases N terminal domain 76 137 2.7E-13 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 Pfam PF08544 GHMP kinases C terminal 198 263 4.5E-6 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 Gene3D G3DSA:3.30.70.890 160 295 7.9E-24 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 Hamap MF_00384 Homoserine kinase [thrB]. 2 294 31.971 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWR56_RS10190 942067366a2d02b0ab8c4489007b79a0 297 Gene3D G3DSA:3.30.230.10 2 159 1.1E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS10585 34a3f45303b950d4a50a91fb342ae391 480 Gene3D G3DSA:1.10.530.10 337 480 9.1E-6 T 29-03-2018 CWR56_RS10585 34a3f45303b950d4a50a91fb342ae391 480 Pfam PF04122 Putative cell wall binding repeat 2 217 273 1.0E-8 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS10585 34a3f45303b950d4a50a91fb342ae391 480 Pfam PF04122 Putative cell wall binding repeat 2 127 208 1.2E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS10585 34a3f45303b950d4a50a91fb342ae391 480 Pfam PF04122 Putative cell wall binding repeat 2 32 115 6.6E-12 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS10585 34a3f45303b950d4a50a91fb342ae391 480 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 349 477 3.8E-10 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 SMART SM00267 179 350 1.7E-6 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 Gene3D G3DSA:3.20.20.450 357 610 7.0E-82 T 29-03-2018 IPR001633 EAL domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 186 342 8.1E-17 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 Gene3D G3DSA:3.30.70.270 184 356 6.5E-24 T 29-03-2018 CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 Pfam PF00990 Diguanylate cyclase, GGDEF domain 190 342 8.9E-16 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 Pfam PF00563 EAL domain 367 601 1.0E-62 T 29-03-2018 IPR001633 EAL domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 SUPERFAMILY SSF141868 366 613 1.96E-76 T 29-03-2018 IPR001633 EAL domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 SMART SM00052 360 606 4.2E-83 T 29-03-2018 IPR001633 EAL domain CWR56_RS07865 134fea59ad3ce50ffaf6de726f1600b4 619 SUPERFAMILY SSF55073 195 352 2.28E-20 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS05650 b358dcac3201c5a2d51231598473d104 74 SMART SM00530 6 61 2.9E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS05650 b358dcac3201c5a2d51231598473d104 74 SUPERFAMILY SSF47413 1 68 2.28E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS05650 b358dcac3201c5a2d51231598473d104 74 Gene3D G3DSA:1.10.260.40 3 74 9.7E-15 T 29-03-2018 CWR56_RS05650 b358dcac3201c5a2d51231598473d104 74 Pfam PF01381 Helix-turn-helix 7 61 1.2E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 Gene3D G3DSA:1.10.10.10 2 68 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 Gene3D G3DSA:3.30.1340.20 73 175 1.1E-32 T 29-03-2018 IPR004173 3H domain GO:0036094 CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 Pfam PF08279 HTH domain 12 65 2.2E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 89 148 2.0E-9 T 29-03-2018 IPR004173 3H domain GO:0036094 CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 PIRSF PIRSF037847 7 175 3.6E-68 T 29-03-2018 IPR026043 Transcription repressor NadR CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 SUPERFAMILY SSF75500 83 174 3.01E-27 T 29-03-2018 IPR004173 3H domain GO:0036094 CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 Pfam PF02829 3H domain 80 174 2.1E-30 T 29-03-2018 IPR004173 3H domain GO:0036094 CWR56_RS18540 974631eca43b29678ad85c58f56ab3b5 175 SUPERFAMILY SSF46785 6 67 3.31E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14990 906de1e9c51b5b893fc67347b2e320f9 381 Gene3D G3DSA:3.40.50.1970 7 180 2.9E-44 T 29-03-2018 CWR56_RS14990 906de1e9c51b5b893fc67347b2e320f9 381 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 372 8.5E-120 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS14990 906de1e9c51b5b893fc67347b2e320f9 381 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWR56_RS14990 906de1e9c51b5b893fc67347b2e320f9 381 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 258 278 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWR56_RS14990 906de1e9c51b5b893fc67347b2e320f9 381 SUPERFAMILY SSF56796 3 378 6.02E-128 T 29-03-2018 CWR56_RS14990 906de1e9c51b5b893fc67347b2e320f9 381 Gene3D G3DSA:1.20.1090.10 182 381 3.2E-66 T 29-03-2018 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Gene3D G3DSA:3.40.50.2300 416 505 4.6E-13 T 29-03-2018 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 SUPERFAMILY SSF63520 205 296 6.15E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Pfam PF08279 HTH domain 4 60 1.1E-10 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 SUPERFAMILY SSF63520 311 414 1.03E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Pfam PF05043 Mga helix-turn-helix domain 82 165 9.0E-12 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 SUPERFAMILY SSF46785 2 45 1.16E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Gene3D G3DSA:1.10.1790.10 300 414 4.7E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Gene3D G3DSA:1.10.1790.10 176 299 1.4E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Gene3D G3DSA:1.10.10.10 86 153 1.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Gene3D G3DSA:1.10.10.10 1 64 3.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Pfam PF00874 PRD domain 220 294 6.9E-10 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15520 15260a55003a2e89bac9a295cce27514 514 Pfam PF00874 PRD domain 328 410 3.5E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Gene3D G3DSA:3.30.450.20 156 286 1.1E-11 T 29-03-2018 CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 SMART SM00267 310 479 4.9E-9 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Gene3D G3DSA:3.30.450.20 42 155 2.3E-10 T 29-03-2018 CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 SUPERFAMILY SSF141868 498 746 3.79E-78 T 29-03-2018 IPR001633 EAL domain CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Pfam PF00563 EAL domain 499 735 1.1E-64 T 29-03-2018 IPR001633 EAL domain CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Pfam PF02743 Cache domain 42 270 1.8E-17 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Gene3D G3DSA:3.30.70.270 306 478 5.2E-24 T 29-03-2018 CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 SUPERFAMILY SSF55073 327 474 7.61E-22 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 SMART SM00052 493 740 8.7E-86 T 29-03-2018 IPR001633 EAL domain CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Gene3D G3DSA:3.20.20.450 492 750 1.1E-84 T 29-03-2018 IPR001633 EAL domain CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 319 464 9.4E-17 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 SUPERFAMILY SSF103190 80 171 3.61E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CWR56_RS14600 e1a77f519f21f3ee2d92a1e8cf755604 759 Pfam PF00990 Diguanylate cyclase, GGDEF domain 321 470 5.9E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS15540 a4d7e0ec19ad72824a2dd9969c8f931a 442 Gene3D G3DSA:1.10.10.10 356 439 8.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 Gene3D G3DSA:3.30.930.10 57 271 7.8E-55 T 29-03-2018 CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 4 319 33.603 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 SUPERFAMILY SSF55681 70 257 5.11E-53 T 29-03-2018 CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 Pfam PF08279 HTH domain 3 56 5.4E-19 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 Gene3D G3DSA:1.10.10.10 2 56 2.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 SUPERFAMILY SSF50037 283 319 9.61E-6 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 SUPERFAMILY SSF46785 4 58 1.27E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 106 209 2.4E-11 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 Gene3D G3DSA:2.30.30.100 273 320 1.4E-9 T 29-03-2018 CWR56_RS17765 3a24fd4c957ede24e195f58385bf8beb 325 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 83 318 1.0E-56 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 121 6.6E-48 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 49 5.6E-20 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 Gene3D G3DSA:3.30.1390.10 51 121 1.9E-31 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 6.5E-31 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 SUPERFAMILY SSF54736 50 121 9.24E-26 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 121 25.424 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 4.0E-19 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 SUPERFAMILY SSF48300 1 57 9.16E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00040 578d97d4dfbbe962f3dec020f0ab1c34 121 Gene3D G3DSA:1.20.5.710 1 50 5.0E-17 T 29-03-2018 CWR56_RS07840 364d81da2d989b09e79f96fe7ae3c3e7 326 SUPERFAMILY SSF51556 1 325 5.1E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS07840 364d81da2d989b09e79f96fe7ae3c3e7 326 Gene3D G3DSA:3.20.20.140 1 326 1.3E-86 T 29-03-2018 CWR56_RS07840 364d81da2d989b09e79f96fe7ae3c3e7 326 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 322 2.8E-83 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CWR56_RS01710 87a2b44369fc98fa028db159ee174dd4 273 Gene3D G3DSA:3.40.50.300 1 259 3.8E-62 T 29-03-2018 CWR56_RS01710 87a2b44369fc98fa028db159ee174dd4 273 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS01710 87a2b44369fc98fa028db159ee174dd4 273 Pfam PF00005 ABC transporter 20 167 2.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01710 87a2b44369fc98fa028db159ee174dd4 273 SUPERFAMILY SSF52540 2 226 3.8E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01710 87a2b44369fc98fa028db159ee174dd4 273 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 12 200 1.2E-70 T 29-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 CWR56_RS01710 87a2b44369fc98fa028db159ee174dd4 273 SMART SM00382 28 214 4.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 SUPERFAMILY SSF51306 86 208 2.96E-34 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 Pfam PF00717 Peptidase S24-like 126 194 4.6E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 TIGRFAM TIGR00498 lexA: repressor LexA 4 210 1.5E-70 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 123 133 1.0E-7 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 163 175 1.0E-7 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 134 145 1.0E-7 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 Gene3D G3DSA:2.10.109.10 92 210 2.7E-25 T 29-03-2018 CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 SUPERFAMILY SSF46785 4 71 1.93E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 Gene3D G3DSA:1.10.10.10 3 69 1.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 Hamap MF_00015 LexA repressor [lexA]. 4 210 33.249 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CWR56_RS09185 bd8878679f46e73ba4a4730af4d7fcde 211 Pfam PF01726 LexA DNA binding domain 4 66 2.3E-22 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CWR56_RS01100 684a7dd06b6e0d7e66854bb9d53864cc 197 Pfam PF00551 Formyl transferase 3 176 1.5E-45 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS01100 684a7dd06b6e0d7e66854bb9d53864cc 197 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 184 29.685 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CWR56_RS01100 684a7dd06b6e0d7e66854bb9d53864cc 197 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 188 6.7E-55 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CWR56_RS01100 684a7dd06b6e0d7e66854bb9d53864cc 197 SUPERFAMILY SSF53328 2 193 1.96E-53 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS01100 684a7dd06b6e0d7e66854bb9d53864cc 197 Gene3D G3DSA:3.40.50.170 1 192 3.5E-60 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 Pfam PF13411 MerR HTH family regulatory protein 3 70 3.5E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 Pfam PF07739 TipAS antibiotic-recognition domain 295 381 1.6E-12 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 Pfam PF07739 TipAS antibiotic-recognition domain 160 290 1.7E-19 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 SUPERFAMILY SSF46955 3 104 3.66E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 SUPERFAMILY SSF89082 297 385 4.71E-5 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 Gene3D G3DSA:1.10.490.50 295 385 2.6E-16 T 29-03-2018 CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 Gene3D G3DSA:1.10.490.50 202 294 1.7E-17 T 29-03-2018 CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 Gene3D G3DSA:1.10.1660.10 1 168 3.3E-27 T 29-03-2018 CWR56_RS08605 c84610b6cb5e3f5b5e559e2e74528ab0 387 SMART SM00422 3 71 6.2E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 SUPERFAMILY SSF52540 3 169 5.16E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Pfam PF09107 Elongation factor SelB, winged helix 581 626 5.0E-16 T 29-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Gene3D G3DSA:2.40.30.10 269 351 5.8E-28 T 29-03-2018 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Gene3D G3DSA:3.40.50.300 1 180 8.0E-34 T 29-03-2018 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Gene3D G3DSA:1.10.10.10 569 626 8.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 29 44 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 SUPERFAMILY SSF46785 578 626 7.48E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Pfam PF00009 Elongation factor Tu GTP binding domain 4 166 3.5E-32 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Pfam PF09106 Elongation factor SelB, winged helix 447 502 5.6E-12 T 29-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Gene3D G3DSA:2.40.30.10 181 268 6.5E-25 T 29-03-2018 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 162 2.7E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Gene3D G3DSA:1.10.10.10 438 502 1.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 PRINTS PR00315 GTP-binding elongation factor signature 5 18 2.0E-6 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 PRINTS PR00315 GTP-binding elongation factor signature 57 67 2.0E-6 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 PRINTS PR00315 GTP-binding elongation factor signature 73 84 2.0E-6 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 SUPERFAMILY SSF46785 436 507 4.62E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 SUPERFAMILY SSF50465 265 364 1.99E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 Pfam PF03144 Elongation factor Tu domain 2 194 261 2.5E-9 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 4 626 2.0E-105 T 29-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CWR56_RS12600 c43c6663b24a40c41c0dc64be4c89e31 627 SUPERFAMILY SSF50447 175 266 7.46E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 Gene3D G3DSA:3.30.70.260 338 407 9.7E-10 T 29-03-2018 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 69 404 2.3E-85 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 SUPERFAMILY SSF55021 337 406 3.66E-9 T 29-03-2018 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 SUPERFAMILY SSF53633 4 248 5.11E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 Pfam PF13840 ACT domain 338 402 2.1E-15 T 29-03-2018 IPR027795 GATS-like ACT domain CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 PIRSF PIRSF000726 1 67 3.8E-13 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 PIRSF PIRSF000726 62 407 1.9E-80 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 Gene3D G3DSA:3.30.70.260 243 337 3.2E-5 T 29-03-2018 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 Gene3D G3DSA:3.40.1160.10 1 242 1.5E-68 T 29-03-2018 CWR56_RS06145 2fa0d90520e172f83b3cde20f6eff2a9 407 Pfam PF00696 Amino acid kinase family 3 237 2.1E-51 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS15265 3da0ad8542bdaf8d5a9d5a9cd87c15dc 261 Gene3D G3DSA:3.40.50.10490 110 241 9.5E-16 T 29-03-2018 CWR56_RS15265 3da0ad8542bdaf8d5a9d5a9cd87c15dc 261 Gene3D G3DSA:1.10.10.10 1 109 5.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15265 3da0ad8542bdaf8d5a9d5a9cd87c15dc 261 SUPERFAMILY SSF53697 83 248 1.64E-24 T 29-03-2018 CWR56_RS15265 3da0ad8542bdaf8d5a9d5a9cd87c15dc 261 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 74 5.1E-20 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS15265 3da0ad8542bdaf8d5a9d5a9cd87c15dc 261 Pfam PF01380 SIS domain 110 242 5.4E-18 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS15265 3da0ad8542bdaf8d5a9d5a9cd87c15dc 261 SUPERFAMILY SSF46689 1 73 3.05E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF12918 TcdB toxin N-terminal helical domain 21 82 4.8E-13 T 29-03-2018 IPR024772 TcdA/TcdB toxin, N-terminal helical domain CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.30.30.20 2154 2174 0.033 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.30.30.20 2021 2072 6.4E-9 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.30.30.20 2472 2494 1.2E-10 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.30.30.20 2403 2450 2.2E-9 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.30.30.20 1927 1957 6.6E-10 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 2439 2535 1.86E-22 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 1863 1916 1.5E-13 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 2495 2528 6.8E-10 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 2355 2375 4.9E-13 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 1958 1977 2.4E-6 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 2107 2128 2.2E-13 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 2247 2288 3.8E-6 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.20.120.10 2451 2471 1.4E-10 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF12919 TcdA/TcdB catalytic glycosyltransferase domain 95 467 9.5E-136 T 29-03-2018 IPR024770 TcdA/TcdB toxin, catalytic glycosyltransferase domain GO:0016757 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 1850 1897 1.08E-20 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 1929 2005 1.08E-20 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 2553 2705 1.81E-26 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF12920 TcdA/TcdB pore forming domain 865 1525 7.0E-233 T 29-03-2018 IPR024769 TcdA/TcdB toxin, pore forming domain GO:0009405 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 1799 1862 1.5E-13 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2376 2402 9.4E-13 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2613 2710 3.1E-17 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2129 2153 1.1E-12 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2175 2246 7.9E-17 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2289 2354 2.8E-20 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2529 2609 3.5E-15 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 1978 2020 1.3E-12 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF53448 1 540 1.57E-143 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 1963 2032 1.1E-50 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 2064 2166 1.1E-50 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 2198 2251 1.1E-50 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 1852 1865 0.026 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2368 2383 0.019 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 1944 1959 0.3 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2481 2496 0.013 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2664 2676 0.098 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2326 2339 0.049 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2573 2588 0.012 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2347 2360 0.049 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2212 2227 0.12 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2120 2135 0.019 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2099 2114 0.019 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 2078 2093 0.085 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF01473 Putative cell wall binding repeat 1987 2001 0.15 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 2311 2411 1.37E-41 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 SUPERFAMILY SSF69360 2189 2279 1.37E-41 T 29-03-2018 CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Pfam PF11713 Peptidase C80 family 577 756 2.7E-51 T 29-03-2018 IPR020974 CGT/MARTX, cysteine protease (CPD) domain CWR56_RS03145 dd2b07566c0c4d41891102354d8d3d61 2710 Gene3D G3DSA:2.10.270.10 2073 2106 1.3E-14 T 29-03-2018 CWR56_RS12075 ef010cfdbd3e0e8251fa0599253e1e6f 234 Gene3D G3DSA:3.50.40.10 58 222 2.3E-26 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS12075 ef010cfdbd3e0e8251fa0599253e1e6f 234 SMART SM00873 63 216 3.3E-17 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS12075 ef010cfdbd3e0e8251fa0599253e1e6f 234 SUPERFAMILY SSF56037 50 227 4.18E-36 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS12075 ef010cfdbd3e0e8251fa0599253e1e6f 234 Pfam PF03483 B3/4 domain 66 196 1.8E-23 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS17245 8dc55e57705b195cd4366570f286c4d4 275 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS17245 8dc55e57705b195cd4366570f286c4d4 275 SUPERFAMILY SSF52518 3 266 1.02E-94 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS17245 8dc55e57705b195cd4366570f286c4d4 275 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 270 7.1E-65 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR56_RS17245 8dc55e57705b195cd4366570f286c4d4 275 Gene3D G3DSA:3.40.50.970 2 270 8.3E-84 T 29-03-2018 CWR56_RS10935 55c312ad56a05445ce9e0f1675dbfa65 208 Gene3D G3DSA:1.10.10.60 2 43 4.6E-16 T 29-03-2018 CWR56_RS10935 55c312ad56a05445ce9e0f1675dbfa65 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 4.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10935 55c312ad56a05445ce9e0f1675dbfa65 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 4.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10935 55c312ad56a05445ce9e0f1675dbfa65 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 3.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10935 55c312ad56a05445ce9e0f1675dbfa65 208 Gene3D G3DSA:1.10.10.60 44 153 8.5E-9 T 29-03-2018 CWR56_RS10935 55c312ad56a05445ce9e0f1675dbfa65 208 SUPERFAMILY SSF46689 2 61 4.87E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 SMART SM00530 9 64 1.2E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 Gene3D G3DSA:2.60.120.10 75 180 1.9E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 SUPERFAMILY SSF51182 49 178 1.17E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 Pfam PF07883 Cupin domain 109 176 6.0E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 Gene3D G3DSA:1.10.260.40 1 74 4.0E-16 T 29-03-2018 CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 Pfam PF01381 Helix-turn-helix 10 61 1.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS08325 978275cbe5e4fd2e97cad38869adfa5b 181 SUPERFAMILY SSF47413 3 68 3.38E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS15650 05378be8b2e68e9eb9c188babcf366e4 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 147 9.5E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15650 05378be8b2e68e9eb9c188babcf366e4 149 Gene3D G3DSA:3.40.930.10 1 149 3.9E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15650 05378be8b2e68e9eb9c188babcf366e4 149 SUPERFAMILY SSF55804 1 148 9.42E-37 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15650 05378be8b2e68e9eb9c188babcf366e4 149 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15650 05378be8b2e68e9eb9c188babcf366e4 149 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 132 8.9E-34 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 SUPERFAMILY SSF81606 378 534 4.45E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 Gene3D G3DSA:3.30.450.40 9 190 1.3E-10 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 SMART SM00331 369 588 7.1E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 Gene3D G3DSA:3.30.450.40 216 337 0.0039 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 396 586 9.3E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 Gene3D G3DSA:3.60.40.10 338 587 5.6E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 SUPERFAMILY SSF55781 193 357 1.42E-6 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 Pfam PF13185 GAF domain 93 174 6.7E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 CWR56_RS13585 c64e1f60b5d0f9693a776d923ab383a1 589 SUPERFAMILY SSF55781 81 175 3.05E-11 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 SUPERFAMILY SSF52540 271 514 2.3E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 SMART SM00382 292 436 8.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 Gene3D G3DSA:1.10.10.60 550 598 3.1E-8 T 29-03-2018 CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 Gene3D G3DSA:3.40.50.300 267 445 2.9E-28 T 29-03-2018 CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 486 495 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 SUPERFAMILY SSF46689 486 599 1.08E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 Gene3D G3DSA:1.10.8.60 446 524 9.8E-19 T 29-03-2018 CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 296 309 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 Pfam PF00158 Sigma-54 interaction domain 272 439 3.3E-69 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS15995 472d728108103f767eeb74e023e5152b 601 Gene3D G3DSA:3.30.450.40 2 146 1.1E-4 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 Pfam PF07729 FCD domain 83 209 4.4E-14 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 SUPERFAMILY SSF46785 10 76 7.44E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 72 1.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 Gene3D G3DSA:1.10.10.10 4 75 3.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 SMART SM00895 82 210 2.8E-8 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 SMART SM00345 14 72 1.8E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 Gene3D G3DSA:1.20.120.530 76 218 2.5E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS03060 5aa231897780cba7f1e76247bca91ae8 219 SUPERFAMILY SSF48008 80 215 1.62E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS02340 3b9d7765238edbcffbe12b46d425ca90 329 Pfam PF00082 Subtilase family 3 226 3.7E-6 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS02340 3b9d7765238edbcffbe12b46d425ca90 329 SUPERFAMILY SSF52743 3 299 7.2E-26 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS02340 3b9d7765238edbcffbe12b46d425ca90 329 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 6 17 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CWR56_RS02340 3b9d7765238edbcffbe12b46d425ca90 329 Gene3D G3DSA:3.40.50.200 2 302 5.0E-24 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS12345 b9d897e7fc1a9eeaa3e190e9d38cfa38 187 SUPERFAMILY SSF69754 2 105 6.28E-30 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS12345 b9d897e7fc1a9eeaa3e190e9d38cfa38 187 Gene3D G3DSA:3.30.160.100 1 97 8.7E-27 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS12345 b9d897e7fc1a9eeaa3e190e9d38cfa38 187 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 1.5E-25 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS12345 b9d897e7fc1a9eeaa3e190e9d38cfa38 187 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 130 183 6.4E-26 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CWR56_RS12345 b9d897e7fc1a9eeaa3e190e9d38cfa38 187 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 3.4E-26 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS12345 b9d897e7fc1a9eeaa3e190e9d38cfa38 187 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 187 22.21 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CWR56_RS08760 109141820252ac878e069ffde3496943 216 Hamap MF_00238 Cytidylate kinase [cmk]. 4 216 32.218 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR56_RS08760 109141820252ac878e069ffde3496943 216 SUPERFAMILY SSF52540 1 215 3.38E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08760 109141820252ac878e069ffde3496943 216 Gene3D G3DSA:3.40.50.300 1 216 3.5E-52 T 29-03-2018 CWR56_RS08760 109141820252ac878e069ffde3496943 216 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 213 1.1E-74 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR56_RS08760 109141820252ac878e069ffde3496943 216 Pfam PF02224 Cytidylate kinase 6 215 2.8E-76 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF56784 573 822 6.05E-67 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF56784 514 534 6.05E-67 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Gene3D G3DSA:1.20.1110.10 281 531 3.9E-46 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 518 524 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Gene3D G3DSA:3.40.1110.10 532 640 2.2E-34 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 438 452 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 305 323 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 123 143 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 285 304 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 692 709 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 749 763 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00943 Copper-transporting ATPase signature 499 514 9.9E-20 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Gene3D G3DSA:3.40.50.1000 641 779 2.0E-45 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Pfam PF00122 E1-E2 ATPase 316 495 8.7E-55 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00942 Copper-transporting ATPase 1 signature 33 56 1.4E-17 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00942 Copper-transporting ATPase 1 signature 102 123 1.4E-17 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00942 Copper-transporting ATPase 1 signature 228 253 1.4E-17 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00942 Copper-transporting ATPase 1 signature 7 32 1.4E-17 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00942 Copper-transporting ATPase 1 signature 171 192 1.4E-17 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 288 795 9.2E-100 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF55008 6 72 1.83E-19 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Gene3D G3DSA:3.30.70.100 78 143 1.1E-22 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Pfam PF00403 Heavy-metal-associated domain 83 142 2.6E-20 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Pfam PF00403 Heavy-metal-associated domain 10 69 1.0E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Gene3D G3DSA:3.30.70.100 5 77 1.2E-18 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 651 4.6E-31 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 365 379 4.6E-31 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 672 4.6E-31 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 715 734 4.6E-31 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 516 530 4.6E-31 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 738 750 4.6E-31 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF81653 317 415 4.58E-29 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF81665 416 510 3.53E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF81665 277 319 3.53E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF81665 764 803 3.53E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 SUPERFAMILY SSF55008 75 143 1.19E-21 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 245 824 2.0E-203 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 226 825 8.8E-192 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 Pfam PF00702 haloacid dehalogenase-like hydrolase 512 729 1.5E-47 T 29-03-2018 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 11 70 1.1E-10 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWR56_RS10160 4eb835f396b7ff997144fe5cb3127c61 833 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 79 142 2.9E-15 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 Gene3D G3DSA:3.30.1650.10 297 471 1.8E-72 T 29-03-2018 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 Gene3D G3DSA:3.40.970.20 474 562 1.5E-43 T 29-03-2018 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 TIGRFAM TIGR00316 cdhC: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit 296 702 1.4E-139 T 29-03-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|KEGG: 00720+2.3.1.169|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726|MetaCyc: PWY-7784 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 Gene3D G3DSA:3.40.1470.10 578 706 7.1E-53 T 29-03-2018 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 Gene3D G3DSA:3.40.50.2030 103 288 4.5E-54 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 SUPERFAMILY SSF56821 7 705 1.83E-233 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 Gene3D G3DSA:1.10.8.190 1 101 7.3E-32 T 29-03-2018 CWR56_RS03525 a4f0449c159ccc73247daa6a81c16309 708 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 297 453 3.3E-72 T 29-03-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|KEGG: 00720+2.3.1.169|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726|MetaCyc: PWY-7784 CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 Gene3D G3DSA:1.10.10.10 124 234 5.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 SUPERFAMILY SSF52172 2 125 3.84E-35 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 Pfam PF00072 Response regulator receiver domain 5 113 3.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 SMART SM00862 157 230 2.1E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 230 1.2E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 SUPERFAMILY SSF46894 138 231 1.02E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 Gene3D G3DSA:3.40.50.2300 1 123 1.1E-29 T 29-03-2018 CWR56_RS04610 4b602f5e2aeae09fdf1a689ae4bcaa65 234 SMART SM00448 3 113 1.5E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS06425 1d99e1d282f94feb3e8973fcf65d0655 139 SUPERFAMILY SSF47413 2 65 1.13E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS06425 1d99e1d282f94feb3e8973fcf65d0655 139 Gene3D G3DSA:1.10.260.40 3 116 1.7E-19 T 29-03-2018 CWR56_RS06425 1d99e1d282f94feb3e8973fcf65d0655 139 SMART SM00530 7 60 1.7E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06425 1d99e1d282f94feb3e8973fcf65d0655 139 Pfam PF12844 Helix-turn-helix domain 5 65 2.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10965 1f3ff5354587199a055e3636b0af5a35 285 Gene3D G3DSA:3.40.50.1820 2 285 2.6E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS10965 1f3ff5354587199a055e3636b0af5a35 285 SUPERFAMILY SSF53474 7 280 1.11E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS10965 1f3ff5354587199a055e3636b0af5a35 285 Pfam PF12146 Serine aminopeptidase, S33 26 268 3.5E-16 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 Pfam PF00990 Diguanylate cyclase, GGDEF domain 34 190 2.8E-26 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 SUPERFAMILY SSF141868 213 461 3.27E-79 T 29-03-2018 IPR001633 EAL domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 Pfam PF00563 EAL domain 214 448 2.1E-63 T 29-03-2018 IPR001633 EAL domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 Gene3D G3DSA:3.30.70.270 26 201 1.4E-26 T 29-03-2018 CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 SMART SM00052 207 453 2.5E-83 T 29-03-2018 IPR001633 EAL domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 Gene3D G3DSA:3.20.20.450 202 467 1.1E-83 T 29-03-2018 IPR001633 EAL domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 33 193 3.8E-18 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 SUPERFAMILY SSF55073 39 195 5.81E-25 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 SMART SM00091 620 691 5.5E-4 T 29-03-2018 IPR000014 PAS domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 622 741 2.5E-7 T 29-03-2018 IPR000014 PAS domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 SUPERFAMILY SSF55785 627 739 9.07E-14 T 29-03-2018 IPR000014 PAS domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 Gene3D G3DSA:3.30.450.20 610 730 9.6E-12 T 29-03-2018 CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 SMART SM00267 21 194 3.9E-24 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06675 862e5addd5b36105a21584e98eacc828 744 Pfam PF08447 PAS fold 645 712 1.3E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 Gene3D G3DSA:1.10.10.10 124 224 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 SUPERFAMILY SSF46894 124 223 2.69E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 Gene3D G3DSA:3.40.50.2300 1 123 1.9E-29 T 29-03-2018 CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 SUPERFAMILY SSF52172 3 118 9.11E-35 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 4.5E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 SMART SM00448 2 112 4.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS07250 c5d7deef25fe4663bcd7fb73acf4419a 224 SMART SM00862 148 223 8.2E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 Gene3D G3DSA:1.20.1270.50 273 366 5.9E-15 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 577 823 2.8E-5 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 SUPERFAMILY SSF74650 378 853 1.6E-28 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 Gene3D G3DSA:2.60.40.1180 367 497 1.2E-7 T 29-03-2018 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 Gene3D G3DSA:3.20.110.10 1 262 3.9E-45 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 Pfam PF09261 Alpha mannosidase middle domain 276 351 5.6E-7 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 SUPERFAMILY SSF88688 281 373 2.09E-8 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 SMART SM00872 274 352 3.3E-4 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 3 259 3.5E-33 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CWR56_RS15020 a2997ed0a394687ac2183367fc3990bc 866 SUPERFAMILY SSF88713 1 267 4.89E-43 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS07465 e3764c78df80d1b315e219ba8e4097a5 196 Gene3D G3DSA:3.40.50.1110 1 196 1.1E-36 T 29-03-2018 CWR56_RS07465 e3764c78df80d1b315e219ba8e4097a5 196 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 5 180 1.8E-24 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR56_RS07465 e3764c78df80d1b315e219ba8e4097a5 196 SUPERFAMILY SSF52266 1 192 3.36E-43 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR56_RS13210 12b6d23f58fe5859b632a9998fa6fe1f 280 Gene3D G3DSA:3.40.50.10440 55 152 3.6E-37 T 29-03-2018 CWR56_RS13210 12b6d23f58fe5859b632a9998fa6fe1f 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 279 6.4E-88 T 29-03-2018 IPR003797 DegV CWR56_RS13210 12b6d23f58fe5859b632a9998fa6fe1f 280 SUPERFAMILY SSF82549 3 278 5.49E-78 T 29-03-2018 CWR56_RS13210 12b6d23f58fe5859b632a9998fa6fe1f 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 277 9.4E-78 T 29-03-2018 IPR003797 DegV CWR56_RS13210 12b6d23f58fe5859b632a9998fa6fe1f 280 Gene3D G3DSA:3.30.1180.10 157 280 8.2E-29 T 29-03-2018 CWR56_RS13210 12b6d23f58fe5859b632a9998fa6fe1f 280 Gene3D G3DSA:2.20.28.50 29 54 9.8E-15 T 29-03-2018 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 Gene3D G3DSA:3.50.50.60 122 183 8.0E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 SUPERFAMILY SSF51905 1 299 9.97E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 287 3.2E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 Gene3D G3DSA:3.50.50.60 1 121 4.9E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 242 2.0E-34 T 29-03-2018 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.0E-34 T 29-03-2018 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 2.0E-34 T 29-03-2018 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-34 T 29-03-2018 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 2.0E-34 T 29-03-2018 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 3 299 3.3E-111 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 56 66 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 299 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 228 249 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.6E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 Gene3D G3DSA:3.50.50.60 184 298 1.3E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS10180 2212a72ae469ecc003f0dcdfb19c5e42 302 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 SUPERFAMILY SSF101386 229 329 3.11E-23 T 29-03-2018 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 Gene3D G3DSA:1.10.287.1080 230 347 8.8E-38 T 29-03-2018 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 SUPERFAMILY SSF53790 2 255 2.18E-27 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 PIRSF PIRSF002845 1 482 4.3E-187 T 29-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 SUPERFAMILY SSF101386 360 455 2.06E-24 T 29-03-2018 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 193 7.4E-22 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 Gene3D G3DSA:3.40.1010.10 1 134 4.1E-14 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 Gene3D G3DSA:1.10.287.1080 362 482 2.7E-25 T 29-03-2018 CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 TIGRFAM TIGR00444 mazG: MazG family protein 237 480 3.0E-87 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 390 449 5.1E-9 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR56_RS17440 64413ea602a0a285bb7ec77e9eb690a9 482 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 253 326 1.6E-27 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 SUPERFAMILY SSF51556 59 364 1.45E-84 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 SUPERFAMILY SSF51338 2 69 4.68E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 Gene3D G3DSA:3.20.20.140 71 350 1.9E-52 T 29-03-2018 CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 SUPERFAMILY SSF51338 370 417 1.4E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 Gene3D G3DSA:2.30.40.10 351 422 0.074 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 Pfam PF01979 Amidohydrolase family 57 417 2.4E-53 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS07920 51d405993d744370c388a728167f3a3c 423 Gene3D G3DSA:2.30.40.10 2 70 7.4E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 SUPERFAMILY SSF55447 165 261 4.71E-15 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 Gene3D G3DSA:3.30.465.10 53 160 1.5E-12 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 SUPERFAMILY SSF56176 5 158 6.54E-21 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 Gene3D G3DSA:3.30.390.50 162 262 3.2E-19 T 29-03-2018 CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 SMART SM01092 165 261 2.0E-10 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 152 3.9E-18 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CWR56_RS10085 2b01dad224100df651c127803b9fe863 262 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 166 261 3.1E-14 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 Pfam PF00733 Asparagine synthase 244 614 1.3E-86 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 39 551 1.5E-120 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 Gene3D G3DSA:3.40.50.620 228 610 9.6E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 Pfam PF13537 Glutamine amidotransferase domain 49 163 3.3E-35 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 SUPERFAMILY SSF52402 471 609 1.01E-67 T 29-03-2018 CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 SUPERFAMILY SSF52402 230 383 1.01E-67 T 29-03-2018 CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 Gene3D G3DSA:3.60.20.10 49 224 4.1E-44 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 PIRSF PIRSF001589 33 624 3.7E-137 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CWR56_RS07760 9038b500fae1e6f7b1e4a5243ed4d140 624 SUPERFAMILY SSF56235 47 218 1.12E-39 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS18380 dcbfcbda6698c5fb293cc67e923950fb 380 PIRSF PIRSF005572 1 380 3.3E-66 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR56_RS18380 dcbfcbda6698c5fb293cc67e923950fb 380 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 2 376 1.5E-157 T 29-03-2018 IPR010969 Cysteine desulfurase-related, unknown function CWR56_RS18380 dcbfcbda6698c5fb293cc67e923950fb 380 Pfam PF00266 Aminotransferase class-V 2 368 7.9E-97 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS18380 dcbfcbda6698c5fb293cc67e923950fb 380 Gene3D G3DSA:3.90.1150.10 253 380 7.4E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS18380 dcbfcbda6698c5fb293cc67e923950fb 380 Gene3D G3DSA:3.40.640.10 13 252 1.5E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS18380 dcbfcbda6698c5fb293cc67e923950fb 380 SUPERFAMILY SSF53383 1 376 9.28E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Gene3D G3DSA:3.40.1390.10 1 97 4.7E-29 T 29-03-2018 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Pfam PF08245 Mur ligase middle domain 107 308 3.9E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Pfam PF01225 Mur ligase family, catalytic domain 23 78 1.5E-11 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Gene3D G3DSA:3.90.190.20 333 484 1.3E-52 T 29-03-2018 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 481 1.1E-162 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 414 8.5E-23 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 SUPERFAMILY SSF63418 1 98 7.59E-24 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 481 34.227 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 SUPERFAMILY SSF53244 328 483 1.83E-51 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 Gene3D G3DSA:3.40.1190.10 98 332 2.2E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13480 dc8d63b10ad234d6a5299559ecedd4be 484 SUPERFAMILY SSF53623 98 321 2.88E-68 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS17780 eda69dd64fe1ff48932b80cbf3b43878 137 Pfam PF09148 Domain of unknown function (DUF1934) 5 132 1.4E-31 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 CWR56_RS17780 eda69dd64fe1ff48932b80cbf3b43878 137 Gene3D G3DSA:2.40.128.20 1 137 4.5E-34 T 29-03-2018 IPR012674 Calycin CWR56_RS17780 eda69dd64fe1ff48932b80cbf3b43878 137 SUPERFAMILY SSF50814 3 134 1.26E-22 T 29-03-2018 IPR012674 Calycin CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 Gene3D G3DSA:3.30.700.10 7 162 8.1E-22 T 29-03-2018 CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 SUPERFAMILY SSF54523 7 80 5.76E-18 T 29-03-2018 CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 4.6E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 27 2.4E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 3.7E-10 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWR56_RS11450 895ec9753e3d91198ff318fa2e05b0aa 162 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 3.7E-10 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWR56_RS14035 c9dded637198fcab53f893fe2ab522e3 703 Gene3D G3DSA:3.20.20.80 16 357 1.0E-49 T 29-03-2018 CWR56_RS14035 c9dded637198fcab53f893fe2ab522e3 703 Pfam PF04122 Putative cell wall binding repeat 2 505 593 5.7E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14035 c9dded637198fcab53f893fe2ab522e3 703 Pfam PF04122 Putative cell wall binding repeat 2 609 676 7.6E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14035 c9dded637198fcab53f893fe2ab522e3 703 Pfam PF04122 Putative cell wall binding repeat 2 404 491 1.3E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14035 c9dded637198fcab53f893fe2ab522e3 703 SUPERFAMILY SSF51445 54 316 6.95E-24 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS14035 c9dded637198fcab53f893fe2ab522e3 703 Pfam PF02638 Glycosyl hydrolase-like 10 31 335 2.4E-93 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 CWR56_RS11360 cde3c384c52565fe529940e374b3c79d 124 PIRSF PIRSF019455 1 124 6.9E-29 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS11360 cde3c384c52565fe529940e374b3c79d 124 Gene3D G3DSA:1.10.4040.10 72 122 1.6E-10 T 29-03-2018 CWR56_RS11360 cde3c384c52565fe529940e374b3c79d 124 Gene3D G3DSA:1.10.10.10 7 71 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11360 cde3c384c52565fe529940e374b3c79d 124 Pfam PF03965 Penicillinase repressor 8 120 2.9E-22 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS11360 cde3c384c52565fe529940e374b3c79d 124 SUPERFAMILY SSF46785 5 123 6.95E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16505 5e6469c2f1a57203b4630de9c9941fc2 789 Pfam PF01228 Glycine radical 668 771 3.3E-32 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CWR56_RS16505 5e6469c2f1a57203b4630de9c9941fc2 789 SUPERFAMILY SSF51998 7 788 3.66E-234 T 29-03-2018 CWR56_RS16505 5e6469c2f1a57203b4630de9c9941fc2 789 Pfam PF02901 Pyruvate formate lyase-like 7 652 2.4E-228 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CWR56_RS16505 5e6469c2f1a57203b4630de9c9941fc2 789 Gene3D G3DSA:3.20.70.20 5 789 4.9E-286 T 29-03-2018 CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 SMART SM00345 11 69 1.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 4.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 4.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 SMART SM00895 79 208 9.9E-5 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 Gene3D G3DSA:1.10.10.10 2 65 5.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 Pfam PF07729 FCD domain 79 207 1.2E-16 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 Gene3D G3DSA:1.20.120.530 66 208 1.5E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 8.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 SUPERFAMILY SSF48008 75 208 5.75E-16 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS14280 19a2d42a3f92ee3208fdb37c8999697f 223 SUPERFAMILY SSF46785 6 73 1.05E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 Gene3D G3DSA:3.40.640.10 122 368 3.1E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 Gene3D G3DSA:1.10.10.10 5 89 3.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 SUPERFAMILY SSF46785 20 89 3.28E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 SUPERFAMILY SSF53383 97 459 1.43E-68 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 Gene3D G3DSA:3.90.1150.10 369 460 2.5E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 Pfam PF00155 Aminotransferase class I and II 105 452 3.6E-28 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 SMART SM00345 28 87 4.1E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS11175 fccbc59ec35adfe6616fcae5368c0ceb 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 3.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 SMART SM00387 222 329 7.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 SUPERFAMILY SSF47384 98 177 7.65E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 Gene3D G3DSA:1.10.287.130 77 173 7.1E-11 T 29-03-2018 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 277 287 6.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 273 6.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 328 6.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 309 6.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 223 328 4.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 Gene3D G3DSA:3.30.565.10 183 329 5.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 SMART SM00388 112 177 3.9E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 Pfam PF00512 His Kinase A (phospho-acceptor) domain 115 177 2.2E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS17910 7911531b2ffa1d4424db36ab4c9f438a 329 SUPERFAMILY SSF55874 167 329 3.41E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 Gene3D G3DSA:1.10.287.130 106 183 7.5E-6 T 29-03-2018 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 Gene3D G3DSA:3.30.565.10 184 343 5.6E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 Pfam PF00512 His Kinase A (phospho-acceptor) domain 124 189 2.8E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 SMART SM00387 234 343 7.6E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 SMART SM00388 123 189 2.7E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 SUPERFAMILY SSF55874 180 341 2.36E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 341 6.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 SUPERFAMILY SSF47384 110 189 5.89E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09335 d5f5407934da5bc3aba7e3662f147908 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 3.9E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 3.9E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 Pfam PF00455 DeoR C terminal sensor domain 77 239 3.6E-39 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 Gene3D G3DSA:3.40.50.1360 75 244 3.7E-27 T 29-03-2018 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 Gene3D G3DSA:1.10.10.10 2 60 9.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 SMART SM01134 75 241 7.3E-51 T 29-03-2018 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 Pfam PF08220 DeoR-like helix-turn-helix domain 8 60 3.6E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 SMART SM00420 8 60 2.7E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 SUPERFAMILY SSF46785 7 63 9.76E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14485 44847cd6bcbfc46cc5c56e2b2c80f93b 261 SUPERFAMILY SSF100950 76 242 1.47E-27 T 29-03-2018 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 Gene3D G3DSA:3.90.780.10 319 508 8.2E-65 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 PRINTS PR01607 Apyrase family signature 30 48 1.8E-33 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 PRINTS PR01607 Apyrase family signature 198 215 1.8E-33 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 PRINTS PR01607 Apyrase family signature 373 396 1.8E-33 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 PRINTS PR01607 Apyrase family signature 250 270 1.8E-33 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 PRINTS PR01607 Apyrase family signature 222 245 1.8E-33 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 PRINTS PR01607 Apyrase family signature 446 465 1.8E-33 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 SUPERFAMILY SSF56300 30 317 5.62E-67 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 SUPERFAMILY SSF55816 316 508 1.44E-59 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 Gene3D G3DSA:3.60.21.10 27 318 4.1E-64 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 Pfam PF00149 Calcineurin-like phosphoesterase 33 239 7.4E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS12825 a3f4b0e36b833f7fe148f7aebef15fa4 613 Pfam PF02872 5'-nucleotidase, C-terminal domain 319 472 5.6E-51 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS10630 6d140d312c4c461d3533698b55558607 476 SUPERFAMILY SSF103473 14 222 4.05E-10 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS10630 6d140d312c4c461d3533698b55558607 476 SUPERFAMILY SSF103473 241 462 1.24E-11 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS10630 6d140d312c4c461d3533698b55558607 476 Pfam PF13347 MFS/sugar transport protein 34 460 1.8E-45 T 29-03-2018 CWR56_RS10630 6d140d312c4c461d3533698b55558607 476 Gene3D G3DSA:1.20.1250.20 14 233 2.0E-9 T 29-03-2018 CWR56_RS10630 6d140d312c4c461d3533698b55558607 476 Gene3D G3DSA:1.20.1250.20 234 476 7.2E-13 T 29-03-2018 CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 SUPERFAMILY SSF54211 3 129 7.21E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 Gene3D G3DSA:3.30.230.30 3 132 1.6E-45 T 29-03-2018 IPR001498 Impact, N-terminal CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 Pfam PF09186 Domain of unknown function (DUF1949) 139 193 1.1E-16 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 Pfam PF01205 Uncharacterized protein family UPF0029 19 120 3.1E-32 T 29-03-2018 IPR001498 Impact, N-terminal CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 201 6.3E-63 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 SUPERFAMILY SSF54980 134 201 3.17E-10 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS03865 db162d0e27984278d75264d1dbc64c2c 214 Gene3D G3DSA:3.30.70.240 134 197 6.9E-15 T 29-03-2018 CWR56_RS11470 af197549a248fdf27b566a39adbc017c 66 SUPERFAMILY SSF47413 5 65 8.58E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS11470 af197549a248fdf27b566a39adbc017c 66 Pfam PF01381 Helix-turn-helix 8 62 4.7E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11470 af197549a248fdf27b566a39adbc017c 66 Gene3D G3DSA:3.30.1190.10 28 66 2.8E-12 T 29-03-2018 CWR56_RS11470 af197549a248fdf27b566a39adbc017c 66 SMART SM00530 7 62 2.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11470 af197549a248fdf27b566a39adbc017c 66 Gene3D G3DSA:1.10.10.10 5 27 0.0011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12640 0965039243cad18465e876261f164543 367 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 222 231 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CWR56_RS12640 0965039243cad18465e876261f164543 367 Pfam PF00155 Aminotransferase class I and II 43 359 1.4E-47 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS12640 0965039243cad18465e876261f164543 367 Gene3D G3DSA:3.90.1150.10 271 363 0.0013 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS12640 0965039243cad18465e876261f164543 367 SUPERFAMILY SSF53383 30 360 5.51E-57 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12640 0965039243cad18465e876261f164543 367 Gene3D G3DSA:3.40.640.10 62 270 7.7E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 SMART SM00533 285 595 1.3E-95 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Gene3D G3DSA:1.10.1420.10 410 539 3.1E-30 T 29-03-2018 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 8 831 2.6E-302 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 PIRSF PIRSF037677 2 853 3.4E-181 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 8 934 24.865 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 694 710 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Pfam PF01624 MutS domain I 9 120 1.2E-43 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Gene3D G3DSA:1.10.1420.10 264 409 5.2E-38 T 29-03-2018 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 SUPERFAMILY SSF53150 118 281 2.22E-31 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 SMART SM00534 613 800 3.5E-119 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Pfam PF05188 MutS domain II 129 255 2.7E-11 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Pfam PF05190 MutS family domain IV 431 522 3.1E-24 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 SUPERFAMILY SSF48334 268 570 1.44E-85 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 SUPERFAMILY SSF52540 571 804 2.21E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Gene3D G3DSA:3.40.50.300 571 849 3.1E-49 T 29-03-2018 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 SUPERFAMILY SSF55271 3 116 5.36E-43 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Gene3D G3DSA:3.40.1170.10 1 132 4.2E-48 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Gene3D G3DSA:3.30.420.110 133 263 7.2E-18 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Pfam PF00488 MutS domain V 617 803 2.1E-86 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS09420 766fcc3e083b44ffa8c02fe89d6eeca6 947 Pfam PF05192 MutS domain III 271 563 8.8E-45 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Gene3D G3DSA:2.40.50.140 138 199 8.4E-14 T 29-03-2018 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Gene3D G3DSA:3.30.1480.10 1 131 2.4E-50 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SUPERFAMILY SSF54814 280 343 1.63E-15 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SMART SM00322 305 368 6.3 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SMART SM00322 231 304 0.47 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Pfam PF13184 NusA-like KH domain 231 298 8.9E-27 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Pfam PF08529 NusA N-terminal domain 4 126 3.8E-45 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SUPERFAMILY SSF54814 201 279 1.96E-30 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SMART SM00316 135 201 9.0E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 344 1.0E-134 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Gene3D G3DSA:3.30.300.20 200 274 3.6E-34 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Gene3D G3DSA:3.30.300.20 275 343 1.5E-17 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SUPERFAMILY SSF69705 1 128 1.57E-43 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Pfam PF00575 S1 RNA binding domain 135 196 2.3E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 384 30.795 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CWR56_RS06070 64413fdf132c600574f949ba587f0486 384 SUPERFAMILY SSF50249 134 200 1.56E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS08665 6807dd749efe102a3f2e8b51c7f74d69 193 Pfam PF02342 TerD domain 1 188 1.6E-82 T 29-03-2018 IPR003325 TerD domain GO:0006950 CWR56_RS08665 6807dd749efe102a3f2e8b51c7f74d69 193 Gene3D G3DSA:2.60.60.30 19 187 3.9E-62 T 29-03-2018 CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 SUPERFAMILY SSF52172 4 180 1.15E-39 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 SMART SM00862 147 222 2.7E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 3.1E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 Pfam PF00072 Response regulator receiver domain 5 112 5.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 Gene3D G3DSA:3.40.50.2300 2 122 6.8E-38 T 29-03-2018 CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 Gene3D G3DSA:1.10.10.10 123 224 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02245 204facf3a7ce79aa7487ac4049f01372 224 SMART SM00448 3 112 3.2E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08645 20a0c48766b8e776d549fffd4791c43d 87 Gene3D G3DSA:4.10.1210.10 1 87 5.9E-28 T 29-03-2018 IPR015073 Atu1913-like CWR56_RS08645 20a0c48766b8e776d549fffd4791c43d 87 SUPERFAMILY SSF141099 1 85 3.14E-33 T 29-03-2018 IPR015073 Atu1913-like CWR56_RS08645 20a0c48766b8e776d549fffd4791c43d 87 Pfam PF08980 Domain of unknown function (DUF1883) 3 86 8.1E-27 T 29-03-2018 IPR015073 Atu1913-like CWR56_RS18390 294ed7fbd21add8c62e7acf463605aed 257 Pfam PF13614 AAA domain 2 178 3.2E-70 T 29-03-2018 IPR025669 AAA domain CWR56_RS18390 294ed7fbd21add8c62e7acf463605aed 257 SUPERFAMILY SSF52540 1 254 1.77E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18390 294ed7fbd21add8c62e7acf463605aed 257 Gene3D G3DSA:3.40.50.300 2 257 2.0E-59 T 29-03-2018 CWR56_RS06540 5addc523448919fb8f8381fe7425577b 287 SUPERFAMILY SSF141986 135 282 4.45E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CWR56_RS06540 5addc523448919fb8f8381fe7425577b 287 Gene3D G3DSA:3.40.50.10740 1 140 1.8E-44 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CWR56_RS06540 5addc523448919fb8f8381fe7425577b 287 PIRSF PIRSF028757 1 287 6.0E-83 T 29-03-2018 IPR003507 Peptidase family S66 CWR56_RS06540 5addc523448919fb8f8381fe7425577b 287 Pfam PF02016 LD-carboxypeptidase 3 276 6.3E-77 T 29-03-2018 IPR003507 Peptidase family S66 CWR56_RS06540 5addc523448919fb8f8381fe7425577b 287 SUPERFAMILY SSF52317 2 145 1.92E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS06540 5addc523448919fb8f8381fe7425577b 287 Gene3D G3DSA:3.50.30.60 141 287 9.3E-41 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 SUPERFAMILY SSF51735 3 151 1.81E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 176 198 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 Gene3D G3DSA:3.40.50.720 1 150 1.8E-30 T 29-03-2018 CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 Pfam PF00742 Homoserine dehydrogenase 130 308 2.2E-56 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 Gene3D G3DSA:3.30.360.10 151 291 7.8E-46 T 29-03-2018 CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 122 2.9E-19 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 PIRSF PIRSF000098 2 404 9.4E-119 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR56_RS07485 9ef9d62209aff00755779f3c693d2a5f 405 SUPERFAMILY SSF55347 130 295 9.81E-45 T 29-03-2018 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 Gene3D G3DSA:3.40.50.1370 1 148 3.6E-54 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 SUPERFAMILY SSF53671 5 332 1.57E-98 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 Gene3D G3DSA:3.40.50.1370 305 338 1.8E-5 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 328 2.3E-55 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 5.4E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 5.4E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 5.4E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 54 73 5.4E-24 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 8 331 80.87 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 85 98 1.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 52 66 1.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 125 139 1.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 1.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 PRINTS PR00102 Ornithine carbamoyltransferase signature 309 320 1.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 9 330 1.7E-125 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 149 6.5E-47 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 54 61 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS09700 9e48914041662cb4c1f0bbe2433733ff 340 Gene3D G3DSA:3.40.50.1370 149 304 1.5E-50 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Gene3D G3DSA:3.30.450.20 316 439 2.6E-8 T 29-03-2018 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Gene3D G3DSA:3.40.190.10 46 201 1.4E-19 T 29-03-2018 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 SUPERFAMILY SSF53850 62 277 3.19E-40 T 29-03-2018 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Pfam PF00512 His Kinase A (phospho-acceptor) domain 447 509 8.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 SMART SM00387 552 660 2.2E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 SMART SM00062 57 279 1.6E-18 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 SUPERFAMILY SSF47384 441 512 3.73E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 61 277 5.0E-39 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Gene3D G3DSA:3.30.565.10 513 663 5.4E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Gene3D G3DSA:1.10.287.130 440 507 3.7E-16 T 29-03-2018 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 SMART SM00388 446 511 7.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 603 9.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 607 617 9.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 657 9.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 620 638 9.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Gene3D G3DSA:3.40.190.10 202 281 1.7E-10 T 29-03-2018 CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 556 659 3.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08335 259466a4979242ac21ba265eeaf7ed1b 664 SUPERFAMILY SSF55874 501 658 1.57E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Gene3D G3DSA:3.20.20.100 1 197 6.1E-43 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 303 314 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Gene3D G3DSA:3.30.70.20 243 302 0.001 T 29-03-2018 CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Gene3D G3DSA:3.20.20.100 198 242 2.4E-8 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Gene3D G3DSA:3.30.70.20 303 327 0.001 T 29-03-2018 CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 SUPERFAMILY SSF46548 253 329 2.25E-10 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Pfam PF00248 Aldo/keto reductase family 14 196 1.8E-32 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Pfam PF00248 Aldo/keto reductase family 197 246 7.6E-7 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 SUPERFAMILY SSF51430 2 274 1.57E-58 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS02585 b3b7af3b6c9b5c9c065cad28b5a354ba 331 Pfam PF13534 4Fe-4S dicluster domain 254 318 7.5E-9 T 29-03-2018 CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 SUPERFAMILY SSF55874 361 494 1.22E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 Gene3D G3DSA:2.60.120.10 1 314 8.2E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 Pfam PF07883 Cupin domain 33 96 2.6E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 SUPERFAMILY SSF51182 4 197 2.37E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 Pfam PF10114 Sensory domain found in PocR 141 234 3.5E-5 T 29-03-2018 IPR018771 PocR domain CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 Gene3D G3DSA:3.30.565.10 349 501 1.3E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14415 50fcbac3a8de57f2100cbdc15df0b1e0 501 Pfam PF06580 Histidine kinase 305 375 3.3E-18 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CWR56_RS08400 45d39035df390fb01e2489e3c4f33a9a 251 Gene3D G3DSA:3.30.420.40 130 251 2.6E-8 T 29-03-2018 CWR56_RS08400 45d39035df390fb01e2489e3c4f33a9a 251 SUPERFAMILY SSF53067 4 247 3.71E-33 T 29-03-2018 CWR56_RS08400 45d39035df390fb01e2489e3c4f33a9a 251 Gene3D G3DSA:3.30.420.40 1 129 2.6E-29 T 29-03-2018 CWR56_RS08400 45d39035df390fb01e2489e3c4f33a9a 251 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 248 2.9E-81 T 29-03-2018 IPR008275 CoA enzyme activase CWR56_RS08400 45d39035df390fb01e2489e3c4f33a9a 251 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 248 6.4E-51 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 302 6.8E-75 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 300 7.0E-29 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 SUPERFAMILY SSF56194 198 303 2.62E-35 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 Gene3D G3DSA:3.30.43.10 16 91 9.2E-26 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 Gene3D G3DSA:3.90.78.10 211 301 3.6E-27 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 Pfam PF01565 FAD binding domain 38 168 6.2E-29 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 SUPERFAMILY SSF56176 9 196 6.07E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 304 91.041 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS16935 cca923ce1ba7b07da4d355a08446c212 304 Gene3D G3DSA:3.30.465.10 92 210 4.2E-37 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 149 3.5E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 Pfam PF02378 Phosphotransferase system, EIIC 304 572 3.8E-11 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 135 8.6E-35 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 Gene3D G3DSA:3.40.50.2300 171 270 9.3E-30 T 29-03-2018 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 SUPERFAMILY SSF55804 3 149 2.75E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 SUPERFAMILY SSF52794 172 268 1.45E-27 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 289 631 1.4E-86 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 Gene3D G3DSA:3.40.930.10 1 153 1.2E-36 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15415 26642f0f47c04cd2fe5bd9b8c438b916 641 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 174 263 3.2E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 Gene3D G3DSA:3.30.565.10 147 306 1.2E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 SUPERFAMILY SSF55874 142 305 2.75E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 Pfam PF00512 His Kinase A (phospho-acceptor) domain 88 151 2.0E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 SMART SM00387 198 307 9.4E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 SMART SM00388 86 152 4.8E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 Gene3D G3DSA:1.10.287.130 77 146 1.1E-9 T 29-03-2018 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 267 285 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 252 262 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 304 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 234 248 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 201 305 3.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01670 8c457e67ef0fd5d16671d6dc6c21eb48 307 SUPERFAMILY SSF47384 76 152 7.26E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 5 505 3.2E-106 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 Pfam PF03023 MviN-like protein 30 459 1.9E-85 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PRINTS PR01806 Virulence factor MviN signature 157 178 1.7E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PRINTS PR01806 Virulence factor MviN signature 34 53 1.7E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PRINTS PR01806 Virulence factor MviN signature 256 282 1.7E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PRINTS PR01806 Virulence factor MviN signature 354 373 1.7E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PRINTS PR01806 Virulence factor MviN signature 133 157 1.7E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PRINTS PR01806 Virulence factor MviN signature 406 423 1.7E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 PIRSF PIRSF002869 1 510 4.9E-129 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14105 032a5c1fad3f8237ab0fbb0a2c0035c9 518 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 4 464 17.109 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 SUPERFAMILY SSF54752 270 327 1.31E-20 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 Gene3D G3DSA:3.40.50.300 28 270 2.5E-47 T 29-03-2018 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 ProSitePatterns PS00321 recA signature. 215 223 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 PRINTS PR00142 RecA protein signature 212 240 1.3E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 PRINTS PR00142 RecA protein signature 95 124 1.3E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 PRINTS PR00142 RecA protein signature 167 196 1.3E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 PRINTS PR00142 RecA protein signature 245 274 1.3E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 PRINTS PR00142 RecA protein signature 299 316 1.3E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 PRINTS PR00142 RecA protein signature 129 158 1.3E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 Pfam PF00154 recA bacterial DNA recombination protein 9 270 1.4E-144 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 SMART SM00382 59 230 4.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 Gene3D G3DSA:3.30.250.10 271 327 7.1E-23 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 SUPERFAMILY SSF52540 9 269 1.29E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 Hamap MF_00268 Protein RecA [recA]. 7 331 52.43 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS06175 a199e87d041940c2ee0fbe24b01a434e 348 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 325 1.1E-173 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 Gene3D G3DSA:3.20.20.70 83 358 3.7E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 Pfam PF04055 Radical SAM superfamily 101 253 2.5E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 Pfam PF13186 Iron-sulfur cluster-binding domain 308 376 4.4E-7 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 SUPERFAMILY SSF102114 97 381 7.32E-51 T 29-03-2018 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 PIRSF PIRSF037420 88 300 6.0E-34 T 29-03-2018 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 PIRSF PIRSF037420 294 410 0.0024 T 29-03-2018 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 308 396 2.1E-10 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 SMART SM00729 96 295 0.0021 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS02335 d7b4d21f50c0b2c426fe870ae73e2520 414 Pfam PF13394 4Fe-4S single cluster domain 102 203 2.7E-12 T 29-03-2018 CWR56_RS06620 9f7accf4067b25d8ba112babc22cc0e3 311 Pfam PF16199 Radical_SAM C-terminal domain 217 300 1.3E-24 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CWR56_RS06620 9f7accf4067b25d8ba112babc22cc0e3 311 SUPERFAMILY SSF102114 5 306 3.14E-53 T 29-03-2018 CWR56_RS06620 9f7accf4067b25d8ba112babc22cc0e3 311 Pfam PF04055 Radical SAM superfamily 50 211 2.2E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS06620 9f7accf4067b25d8ba112babc22cc0e3 311 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 12 310 1.6E-120 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 CWR56_RS06620 9f7accf4067b25d8ba112babc22cc0e3 311 SMART SM00729 29 256 7.1E-41 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS06620 9f7accf4067b25d8ba112babc22cc0e3 311 Gene3D G3DSA:3.20.20.70 3 283 2.2E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 SUPERFAMILY SSF52540 417 704 7.7E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 Pfam PF01580 FtsK/SpoIIIE family 445 581 4.3E-44 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 Pfam PF09397 Ftsk gamma domain 732 792 1.0E-29 T 29-03-2018 IPR018541 FtsK gamma domain CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 SUPERFAMILY SSF46785 730 797 2.09E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 SMART SM00382 480 652 8.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 Gene3D G3DSA:3.40.50.300 344 803 2.0E-55 T 29-03-2018 CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 SMART SM00843 730 795 6.7E-39 T 29-03-2018 IPR018541 FtsK gamma domain CWR56_RS06155 ebcb81b847e4bff127ea254ab1427794 803 SUPERFAMILY SSF103473 20 172 6.93E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS08055 165f9b953d4630522420028c043269b2 242 Pfam PF08713 DNA alkylation repair enzyme 29 204 2.0E-18 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CWR56_RS08055 165f9b953d4630522420028c043269b2 242 Gene3D G3DSA:1.25.40.290 125 223 1.5E-14 T 29-03-2018 CWR56_RS08055 165f9b953d4630522420028c043269b2 242 Gene3D G3DSA:1.20.1660.10 14 121 2.2E-24 T 29-03-2018 CWR56_RS08055 165f9b953d4630522420028c043269b2 242 SUPERFAMILY SSF48371 21 220 4.03E-41 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWR56_RS14835 ad3f0ba556817665b7d1e8ec5f9ad475 245 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 45 239 3.3E-25 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CWR56_RS14835 ad3f0ba556817665b7d1e8ec5f9ad475 245 Pfam PF01881 CRISPR associated protein Cas6 93 240 6.2E-26 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 Gene3D G3DSA:3.40.50.300 486 745 6.0E-72 T 29-03-2018 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 Gene3D G3DSA:1.20.1560.10 1 480 2.2E-86 T 29-03-2018 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 ProSitePatterns PS00211 ABC transporters family signature. 641 655 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 SUPERFAMILY SSF90123 3 41 2.22E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 SUPERFAMILY SSF90123 209 478 2.22E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 Pfam PF00005 ABC transporter 520 667 1.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 SUPERFAMILY SSF52540 498 739 4.31E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 Pfam PF00664 ABC transporter transmembrane region 220 454 3.1E-33 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS10680 39d8fc1730bd5db2746aae094f4a6ae4 748 SMART SM00382 529 714 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 Gene3D G3DSA:3.40.50.720 4 180 8.6E-47 T 29-03-2018 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 Gene3D G3DSA:1.10.1040.10 182 332 5.0E-53 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 SUPERFAMILY SSF48179 182 334 2.89E-56 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 321 2.8E-53 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PIRSF PIRSF000114 2 334 7.9E-112 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 2.7E-46 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 2.7E-46 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 2.7E-46 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 2.7E-46 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 2.7E-46 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 2.7E-46 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 161 5.2E-56 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 SUPERFAMILY SSF51735 7 180 1.52E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS13310 92ca5c4bc6511f24867653ac16580606 343 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 324 37.531 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 PRINTS PR00471 Acetate kinase family signature 271 284 1.8E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 PRINTS PR00471 Acetate kinase family signature 177 198 1.8E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 PRINTS PR00471 Acetate kinase family signature 294 310 1.8E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 PRINTS PR00471 Acetate kinase family signature 3 14 1.8E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 Hamap MF_00542 Probable butyrate kinase [buk]. 1 352 141.453 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 177 194 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 Pfam PF00871 Acetokinase family 2 326 5.6E-57 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 2 350 1.5E-142 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 SUPERFAMILY SSF53067 148 345 3.7E-46 T 29-03-2018 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 Gene3D G3DSA:3.30.420.40 178 336 1.1E-42 T 29-03-2018 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 SUPERFAMILY SSF53067 2 169 2.76E-64 T 29-03-2018 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 Gene3D G3DSA:3.30.420.40 1 177 5.3E-53 T 29-03-2018 CWR56_RS12245 5bd1d35e1d4f2f464e4e2705002bc699 352 PIRSF PIRSF036458 1 352 2.5E-143 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 SUPERFAMILY SSF48179 186 330 1.7E-63 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 Gene3D G3DSA:3.40.50.720 8 73 4.1E-4 T 29-03-2018 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 180 1.0E-77 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 Gene3D G3DSA:1.10.1040.10 74 331 2.3E-114 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 PIRSF PIRSF000116 2 208 2.4E-43 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 PIRSF PIRSF000116 204 331 7.9E-14 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 4 331 43.594 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 SUPERFAMILY SSF51735 5 185 1.14E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 186 328 1.2E-62 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR56_RS07420 997295f3157fe9a963bc0482e56be42e 331 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 17 330 1.1E-135 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 SUPERFAMILY SSF50249 2 79 1.88E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 Pfam PF02565 Recombination protein O C terminal 84 241 4.0E-34 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 Hamap MF_00201 DNA repair protein RecO [recO]. 2 247 26.089 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 Gene3D G3DSA:2.40.50.140 3 82 2.0E-24 T 29-03-2018 CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 Pfam PF11967 Recombination protein O N terminal 1 79 5.9E-25 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 SUPERFAMILY SSF57863 81 234 1.73E-33 T 29-03-2018 CWR56_RS12295 0e6db4400c39ef84e3d246cc69a66488 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 245 2.9E-51 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWR56_RS03205 b071d7ca9ab7bacdb2c72d7ee92f1463 261 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 17 244 7.3E-19 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR56_RS03205 b071d7ca9ab7bacdb2c72d7ee92f1463 261 Gene3D G3DSA:3.40.1390.30 106 230 2.0E-15 T 29-03-2018 CWR56_RS03205 b071d7ca9ab7bacdb2c72d7ee92f1463 261 Gene3D G3DSA:3.40.1390.30 2 105 9.2E-10 T 29-03-2018 CWR56_RS03205 b071d7ca9ab7bacdb2c72d7ee92f1463 261 SUPERFAMILY SSF102705 6 251 7.32E-31 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 Pfam PF00465 Iron-containing alcohol dehydrogenase 477 869 6.0E-117 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 Gene3D G3DSA:3.40.50.1970 450 664 3.1E-53 T 29-03-2018 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 741 761 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 PIRSF PIRSF000111 13 884 0.0 T 29-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 SUPERFAMILY SSF56796 468 883 6.28E-124 T 29-03-2018 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 Pfam PF00171 Aldehyde dehydrogenase family 11 289 3.2E-21 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 Gene3D G3DSA:1.20.1090.10 665 884 3.0E-66 T 29-03-2018 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 Gene3D G3DSA:3.40.605.10 3 246 1.4E-29 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 SUPERFAMILY SSF53720 31 473 9.56E-78 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS14755 19125d624381848dfb70aa70b01ec878 884 Gene3D G3DSA:3.40.309.10 247 422 1.0E-26 T 29-03-2018 CWR56_RS16410 7c320da5a9cbae33eaecdaa160fd6261 305 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 25 302 1.2E-81 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CWR56_RS16410 7c320da5a9cbae33eaecdaa160fd6261 305 SUPERFAMILY SSF161098 29 299 8.5E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS16410 7c320da5a9cbae33eaecdaa160fd6261 305 Gene3D G3DSA:1.10.3720.10 19 298 1.6E-39 T 29-03-2018 CWR56_RS16410 7c320da5a9cbae33eaecdaa160fd6261 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 296 1.3E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS09630 1125cc4ea81f1f7b0ebc6c8b2e76eff2 123 SMART SM00530 7 62 1.9E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09630 1125cc4ea81f1f7b0ebc6c8b2e76eff2 123 Pfam PF01381 Helix-turn-helix 8 62 3.9E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09630 1125cc4ea81f1f7b0ebc6c8b2e76eff2 123 SUPERFAMILY SSF47413 1 69 1.31E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS09630 1125cc4ea81f1f7b0ebc6c8b2e76eff2 123 Gene3D G3DSA:1.10.260.40 3 115 4.8E-23 T 29-03-2018 CWR56_RS16925 975cdb3404200c133dbe84c2dcb117dd 285 SUPERFAMILY SSF52540 1 155 3.1E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16925 975cdb3404200c133dbe84c2dcb117dd 285 Gene3D G3DSA:3.40.50.300 1 156 6.7E-13 T 29-03-2018 CWR56_RS16925 975cdb3404200c133dbe84c2dcb117dd 285 Pfam PF03668 P-loop ATPase protein family 1 281 1.3E-97 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CWR56_RS16925 975cdb3404200c133dbe84c2dcb117dd 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 40.286 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CWR56_RS16925 975cdb3404200c133dbe84c2dcb117dd 285 PIRSF PIRSF005052 1 285 3.1E-108 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CWR56_RS03645 dca013561111998a215154dee188b4e3 225 SUPERFAMILY SSF161098 15 210 9.68E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS03645 dca013561111998a215154dee188b4e3 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 222 1.4E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS03645 dca013561111998a215154dee188b4e3 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 116 7.6E-27 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWR56_RS03645 dca013561111998a215154dee188b4e3 225 Gene3D G3DSA:1.10.3720.10 2 225 4.0E-49 T 29-03-2018 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 Gene3D G3DSA:2.30.140.10 1 52 1.1E-20 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 Pfam PF17284 Spermidine synthase tetramerisation domain 3 54 6.3E-15 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 TIGRFAM TIGR00417 speE: spermidine synthase 4 275 3.0E-94 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 Pfam PF01564 Spermine/spermidine synthase domain 58 243 2.3E-56 T 29-03-2018 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 Gene3D G3DSA:3.40.50.150 55 283 1.7E-41 T 29-03-2018 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 281 39.057 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CWR56_RS04375 a9f061a96cf709a0925048d5ec009048 283 SUPERFAMILY SSF53335 3 281 2.02E-83 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS02570 6ca64e6086ba92c23c2eea1cc8d561f6 309 Gene3D G3DSA:3.40.710.10 3 309 9.0E-124 T 29-03-2018 CWR56_RS02570 6ca64e6086ba92c23c2eea1cc8d561f6 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 1.5E-125 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CWR56_RS02570 6ca64e6086ba92c23c2eea1cc8d561f6 309 SUPERFAMILY SSF56601 6 309 7.8E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS02570 6ca64e6086ba92c23c2eea1cc8d561f6 309 Pfam PF04960 Glutaminase 23 309 7.6E-119 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CWR56_RS02570 6ca64e6086ba92c23c2eea1cc8d561f6 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 45.896 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CWR56_RS16645 5b4f7ae2e6dbfff3820faf87773bb233 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 305 3.1E-10 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR56_RS16645 5b4f7ae2e6dbfff3820faf87773bb233 312 SUPERFAMILY SSF51735 96 275 8.79E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16645 5b4f7ae2e6dbfff3820faf87773bb233 312 Gene3D G3DSA:3.40.50.720 1 105 1.5E-17 T 29-03-2018 CWR56_RS16645 5b4f7ae2e6dbfff3820faf87773bb233 312 Gene3D G3DSA:3.40.50.720 106 275 1.9E-41 T 29-03-2018 CWR56_RS16645 5b4f7ae2e6dbfff3820faf87773bb233 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 273 2.6E-48 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR56_RS16645 5b4f7ae2e6dbfff3820faf87773bb233 312 SUPERFAMILY SSF52283 1 124 4.46E-13 T 29-03-2018 CWR56_RS09285 a285d8f1e52a852dafaea7a3d9e24df5 286 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 12 219 1.3E-64 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS09285 a285d8f1e52a852dafaea7a3d9e24df5 286 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 224 278 4.5E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CWR56_RS09285 a285d8f1e52a852dafaea7a3d9e24df5 286 PIRSF PIRSF006483 1 286 1.1E-87 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS03650 384ccbd2cb8253f0ad11658bc13c13c9 240 SUPERFAMILY SSF52540 1 235 3.19E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03650 384ccbd2cb8253f0ad11658bc13c13c9 240 PIRSF PIRSF039085 1 240 7.4E-116 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWR56_RS03650 384ccbd2cb8253f0ad11658bc13c13c9 240 Gene3D G3DSA:3.40.50.300 1 239 5.0E-81 T 29-03-2018 CWR56_RS03650 384ccbd2cb8253f0ad11658bc13c13c9 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS03650 384ccbd2cb8253f0ad11658bc13c13c9 240 SMART SM00382 26 213 1.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03650 384ccbd2cb8253f0ad11658bc13c13c9 240 Pfam PF00005 ABC transporter 17 165 5.1E-39 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 Pfam PF00677 Lumazine binding domain 99 183 1.2E-19 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 Pfam PF00677 Lumazine binding domain 3 86 3.5E-22 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 SUPERFAMILY SSF63380 1 87 9.35E-24 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 3.4E-65 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 Gene3D G3DSA:2.40.30.20 93 190 6.0E-29 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 SUPERFAMILY SSF63380 92 197 1.02E-29 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 Gene3D G3DSA:2.40.30.20 1 92 1.0E-26 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS08125 dd56437d534858ca7285e0f0f2384ca2 221 PIRSF PIRSF000498 1 211 6.8E-72 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR56_RS04810 9e4b6978b69837ba32654206dc739e1f 189 SUPERFAMILY SSF56300 1 161 9.99E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS04810 9e4b6978b69837ba32654206dc739e1f 189 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 161 9.1E-24 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CWR56_RS04810 9e4b6978b69837ba32654206dc739e1f 189 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 161 1.1E-27 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CWR56_RS04810 9e4b6978b69837ba32654206dc739e1f 189 Gene3D G3DSA:3.60.21.10 1 171 7.5E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 SUPERFAMILY SSF109604 8 192 4.08E-75 T 29-03-2018 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 28 731 5.4E-254 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 SUPERFAMILY SSF55021 660 734 6.62E-9 T 29-03-2018 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 SMART SM00954 237 347 2.6E-71 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Pfam PF02824 TGS domain 390 449 4.5E-20 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 SUPERFAMILY SSF81301 182 394 2.13E-67 T 29-03-2018 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 SUPERFAMILY SSF81271 377 449 2.78E-22 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Gene3D G3DSA:3.30.460.10 190 328 1.9E-44 T 29-03-2018 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Pfam PF13291 ACT domain 655 732 2.3E-19 T 29-03-2018 IPR002912 ACT domain CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 SMART SM00471 43 155 3.7E-12 T 29-03-2018 IPR003607 HD/PDEase domain CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Gene3D G3DSA:3.30.70.260 655 735 8.3E-9 T 29-03-2018 CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Pfam PF13328 HD domain 28 177 2.2E-50 T 29-03-2018 IPR003607 HD/PDEase domain CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Gene3D G3DSA:3.10.20.30 384 457 1.2E-23 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS13915 dfd9774dad42e73511d49c0b9b95549e 735 Pfam PF04607 Region found in RelA / SpoT proteins 237 346 1.1E-40 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 Pfam PF13186 Iron-sulfur cluster-binding domain 345 407 3.5E-6 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 SUPERFAMILY SSF102114 94 416 4.32E-58 T 29-03-2018 CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 345 432 5.7E-21 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 Pfam PF04055 Radical SAM superfamily 99 254 1.9E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 TIGRFAM TIGR03974 rSAM_six_Cys: SCIFF radical SAM maturase 4 450 1.8E-222 T 29-03-2018 IPR024025 SCIFF radical SAM maturase CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 Gene3D G3DSA:3.20.20.70 86 419 4.4E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 14 70 8.1E-6 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D CWR56_RS13940 70d0e6f2bce5aa43f4e04183fb25268a 459 Pfam PF13353 4Fe-4S single cluster domain 100 231 3.0E-14 T 29-03-2018 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Pfam PF12836 Helix-hairpin-helix motif 477 541 2.1E-28 T 29-03-2018 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Pfam PF09371 Tex-like protein N-terminal domain 8 190 1.6E-67 T 29-03-2018 IPR018974 Tex-like protein, N-terminal CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SMART SM00316 641 712 4.1E-23 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SUPERFAMILY SSF47781 546 624 5.78E-18 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SUPERFAMILY SSF47781 456 542 7.56E-26 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Pfam PF00575 S1 RNA binding domain 641 712 9.3E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SUPERFAMILY SSF50249 624 713 2.76E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Gene3D G3DSA:1.10.3500.10 341 484 4.4E-39 T 29-03-2018 IPR023323 Tex-like domain CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SUPERFAMILY SSF53098 308 455 1.44E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Gene3D G3DSA:1.10.10.650 1 100 1.8E-34 T 29-03-2018 IPR023319 Tex-like protein, HTH domain CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Gene3D G3DSA:1.10.3500.10 101 340 2.2E-78 T 29-03-2018 IPR023323 Tex-like domain CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Pfam PF16921 Tex protein YqgF-like domain 312 437 8.4E-57 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SMART SM00732 312 410 5.5E-34 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 SUPERFAMILY SSF158832 2 307 2.22E-109 T 29-03-2018 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Gene3D G3DSA:2.40.50.140 632 713 6.9E-24 T 29-03-2018 CWR56_RS00695 d4c9282966fd0095d0e5fecbb206b328 713 Gene3D G3DSA:1.10.150.310 485 622 2.1E-48 T 29-03-2018 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SUPERFAMILY SSF54980 353 431 6.83E-21 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Gene3D G3DSA:3.30.70.240 556 634 1.8E-26 T 29-03-2018 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Gene3D G3DSA:2.40.30.10 250 349 1.4E-24 T 29-03-2018 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SUPERFAMILY SSF54980 550 637 1.94E-27 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SUPERFAMILY SSF54211 431 546 2.38E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SMART SM00889 429 545 5.0E-68 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Pfam PF03764 Elongation factor G, domain IV 429 544 1.3E-41 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Gene3D G3DSA:3.40.50.300 2 249 5.1E-37 T 29-03-2018 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Gene3D G3DSA:3.30.70.870 350 440 9.5E-25 T 29-03-2018 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Gene3D G3DSA:3.30.230.10 441 555 5.4E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.8E-7 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 PRINTS PR00315 GTP-binding elongation factor signature 114 123 1.8E-7 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 PRINTS PR00315 GTP-binding elongation factor signature 64 74 1.8E-7 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 PRINTS PR00315 GTP-binding elongation factor signature 80 91 1.8E-7 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Pfam PF14492 Elongation Factor G, domain II 353 426 1.5E-26 T 29-03-2018 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 148 1.4E-16 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Pfam PF03144 Elongation factor Tu domain 2 273 339 3.0E-7 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SMART SM00838 547 635 1.4E-41 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Pfam PF00679 Elongation factor G C-terminus 547 634 4.2E-29 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SUPERFAMILY SSF52540 5 248 5.85E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 Pfam PF00009 Elongation factor Tu GTP binding domain 9 249 4.8E-28 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS18835 dc34bab58f0d3ef3408971980f2b39f1 642 SUPERFAMILY SSF50447 233 353 1.06E-27 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS05070 81297811ba559a0e6a931bc651335499 290 Gene3D G3DSA:3.60.21.10 42 290 7.3E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05070 81297811ba559a0e6a931bc651335499 290 SUPERFAMILY SSF56300 45 286 2.95E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS05070 81297811ba559a0e6a931bc651335499 290 Pfam PF00149 Calcineurin-like phosphoesterase 45 225 1.6E-17 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS17225 d85affe0cf4746d135c7c913d59695ac 189 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 181 1.2E-50 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWR56_RS17225 d85affe0cf4746d135c7c913d59695ac 189 SUPERFAMILY SSF100950 1 187 3.77E-49 T 29-03-2018 CWR56_RS17225 d85affe0cf4746d135c7c913d59695ac 189 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 181 3.9E-39 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWR56_RS17225 d85affe0cf4746d135c7c913d59695ac 189 Gene3D G3DSA:3.40.50.10420 1 189 3.8E-53 T 29-03-2018 CWR56_RS17225 d85affe0cf4746d135c7c913d59695ac 189 PIRSF PIRSF006806 1 184 2.0E-44 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Gene3D G3DSA:3.30.420.40 3 80 4.3E-4 T 29-03-2018 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 915 1234 9.6E-49 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 SUPERFAMILY SSF53067 6 256 3.48E-52 T 29-03-2018 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Gene3D G3DSA:3.30.420.40 291 422 2.6E-8 T 29-03-2018 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 6 256 1.5E-37 T 29-03-2018 IPR008275 CoA enzyme activase CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 322 575 6.0E-41 T 29-03-2018 IPR008275 CoA enzyme activase CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Gene3D G3DSA:3.30.420.40 423 561 5.6E-32 T 29-03-2018 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Gene3D G3DSA:3.30.420.40 98 238 1.5E-25 T 29-03-2018 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 SUPERFAMILY SSF53067 321 576 7.89E-52 T 29-03-2018 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 322 576 1.5E-33 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 7 253 1.8E-20 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR56_RS08515 bd1c17a99e5ed055c73d52cc81b19be5 1417 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 678 900 5.4E-79 T 29-03-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 SUPERFAMILY SSF52440 1 94 3.84E-29 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 Pfam PF07478 D-ala D-ala ligase C-terminus 103 295 7.1E-42 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 SUPERFAMILY SSF56059 95 294 5.89E-47 T 29-03-2018 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 297 5.3E-84 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 62 73 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 PIRSF PIRSF039102 1 51 4.0E-13 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 PIRSF PIRSF039102 46 299 5.2E-82 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 241 268 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 Pfam PF01820 D-ala D-ala ligase N-terminus 2 85 1.4E-22 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 Gene3D G3DSA:3.30.470.20 165 299 2.2E-29 T 29-03-2018 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 Gene3D G3DSA:3.30.1490.20 98 164 2.2E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 Gene3D G3DSA:3.40.50.20 1 97 5.0E-35 T 29-03-2018 CWR56_RS06590 f300cf2c1bece001fc8cc9353e277d81 299 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 298 33.564 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 Gene3D G3DSA:3.30.460.10 6 146 2.7E-50 T 29-03-2018 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 SUPERFAMILY SSF81891 146 445 4.19E-56 T 29-03-2018 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 Pfam PF01743 Poly A polymerase head domain 27 147 2.6E-36 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 231 1.7E-16 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 Gene3D G3DSA:1.10.3090.10 147 437 4.0E-65 T 29-03-2018 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 SUPERFAMILY SSF81301 10 144 1.96E-41 T 29-03-2018 CWR56_RS12465 731e7f7359a57b3f42774def9a78d0a4 448 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 299 442 6.2E-15 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 SMART SM00859 5 122 1.2E-45 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 328 35.784 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 SUPERFAMILY SSF55347 130 315 3.55E-70 T 29-03-2018 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 121 1.5E-33 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 SUPERFAMILY SSF51735 3 157 6.59E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 326 9.9E-135 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 314 1.8E-47 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 PIRSF PIRSF000148 3 333 1.9E-125 T 29-03-2018 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 Gene3D G3DSA:3.30.360.10 143 310 3.9E-65 T 29-03-2018 CWR56_RS16200 40116731a4c4a1a562394d43fddc9698 333 Gene3D G3DSA:3.40.50.720 1 142 1.9E-32 T 29-03-2018 CWR56_RS07400 683fe252186733382a53930b9a07b6a1 251 Pfam PF11738 Protein of unknown function (DUF3298) 162 243 8.3E-19 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS07400 683fe252186733382a53930b9a07b6a1 251 Gene3D G3DSA:3.90.640.20 157 250 6.9E-22 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS07400 683fe252186733382a53930b9a07b6a1 251 Gene3D G3DSA:3.30.565.40 44 156 4.3E-11 T 29-03-2018 CWR56_RS07400 683fe252186733382a53930b9a07b6a1 251 Pfam PF13739 Domain of unknown function (DUF4163) 57 132 3.8E-7 T 29-03-2018 IPR025303 Deacetylase PdaC CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 SUPERFAMILY SSF47203 226 378 2.09E-62 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 Gene3D G3DSA:1.10.540.10 3 119 5.1E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 Gene3D G3DSA:2.40.110.10 120 216 1.0E-38 T 29-03-2018 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 Gene3D G3DSA:1.20.140.10 217 378 5.9E-67 T 29-03-2018 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 SUPERFAMILY SSF56645 5 241 1.44E-88 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 117 3.1E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 374 1.5E-55 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 8.1E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CWR56_RS04845 8a90b6ea498d5d1d92560fb0700146a6 378 PIRSF PIRSF016578 18 377 1.5E-25 T 29-03-2018 CWR56_RS01400 097403f1e5954622a52881267b675485 645 PRINTS PR00775 90kDa heat shock protein signature 171 188 1.2E-31 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CWR56_RS01400 097403f1e5954622a52881267b675485 645 PRINTS PR00775 90kDa heat shock protein signature 189 207 1.2E-31 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CWR56_RS01400 097403f1e5954622a52881267b675485 645 PRINTS PR00775 90kDa heat shock protein signature 119 141 1.2E-31 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CWR56_RS01400 097403f1e5954622a52881267b675485 645 PRINTS PR00775 90kDa heat shock protein signature 74 91 1.2E-31 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CWR56_RS01400 097403f1e5954622a52881267b675485 645 PRINTS PR00775 90kDa heat shock protein signature 92 109 1.2E-31 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CWR56_RS01400 097403f1e5954622a52881267b675485 645 PRINTS PR00775 90kDa heat shock protein signature 25 47 1.2E-31 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CWR56_RS01400 097403f1e5954622a52881267b675485 645 SUPERFAMILY SSF55874 3 209 2.74E-53 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01400 097403f1e5954622a52881267b675485 645 Pfam PF00183 Hsp90 protein 185 643 2.5E-64 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CWR56_RS01400 097403f1e5954622a52881267b675485 645 Gene3D G3DSA:3.30.565.10 2 226 1.4E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01400 097403f1e5954622a52881267b675485 645 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 31 144 3.8E-11 T 29-03-2018 CWR56_RS01400 097403f1e5954622a52881267b675485 645 SUPERFAMILY SSF54211 249 495 8.34E-71 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS01400 097403f1e5954622a52881267b675485 645 SUPERFAMILY SSF110942 523 639 4.97E-9 T 29-03-2018 CWR56_RS01400 097403f1e5954622a52881267b675485 645 PIRSF PIRSF002583 1 644 5.4E-159 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CWR56_RS00650 0cacbde0d760a5a1ceca6dea27a082e1 108 Gene3D G3DSA:3.40.50.2300 4 108 7.4E-34 T 29-03-2018 CWR56_RS00650 0cacbde0d760a5a1ceca6dea27a082e1 108 SUPERFAMILY SSF52794 3 106 5.49E-32 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS00650 0cacbde0d760a5a1ceca6dea27a082e1 108 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 97 6.4E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS08015 3976ded977821f9f594f969ea32840fa 221 Pfam PF06149 Protein of unknown function (DUF969) 1 216 1.6E-87 T 29-03-2018 IPR010374 Protein of unknown function DUF969 CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 Gene3D G3DSA:3.40.50.1000 139 250 5.2E-13 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 Gene3D G3DSA:3.40.50.1000 1 138 1.0E-21 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 228 1.9E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 255 1.3E-56 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 ProSitePatterns PS01229 Hypothetical cof family signature 2. 209 231 - T 29-03-2018 CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 SUPERFAMILY SSF56784 1 259 3.2E-67 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14020 75c216d3f3a0ca2c6a86069eb82d21b7 262 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 1.5E-54 T 29-03-2018 IPR000150 Cof family GO:0016787 CWR56_RS04050 227dc4e3b2ae100be231a63ab043bf1f 128 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 7 36 4.0E-8 T 29-03-2018 IPR004462 Desulforodoxin domain GO:0005506 CWR56_RS04050 227dc4e3b2ae100be231a63ab043bf1f 128 Pfam PF01880 Desulfoferrodoxin 42 126 1.1E-24 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CWR56_RS04050 227dc4e3b2ae100be231a63ab043bf1f 128 SUPERFAMILY SSF57802 4 37 1.26E-9 T 29-03-2018 CWR56_RS04050 227dc4e3b2ae100be231a63ab043bf1f 128 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 41 127 1.4E-21 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CWR56_RS04050 227dc4e3b2ae100be231a63ab043bf1f 128 SUPERFAMILY SSF49367 34 127 3.4E-32 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CWR56_RS04050 227dc4e3b2ae100be231a63ab043bf1f 128 Gene3D G3DSA:2.60.40.730 2 128 1.1E-48 T 29-03-2018 CWR56_RS07010 61fd58821785e3c01259767dc1d1ef47 314 SUPERFAMILY SSF46785 1 62 2.51E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07010 61fd58821785e3c01259767dc1d1ef47 314 Pfam PF08279 HTH domain 6 60 3.0E-12 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS07010 61fd58821785e3c01259767dc1d1ef47 314 Gene3D G3DSA:1.10.10.10 1 64 8.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07010 61fd58821785e3c01259767dc1d1ef47 314 Pfam PF13280 WYL domain 139 307 6.5E-22 T 29-03-2018 IPR026881 WYL domain CWR56_RS02860 22a3b79098c32cb826737e1f466d823d 189 Gene3D G3DSA:3.30.460.10 15 186 1.9E-45 T 29-03-2018 CWR56_RS02860 22a3b79098c32cb826737e1f466d823d 189 SUPERFAMILY SSF81301 21 184 3.07E-45 T 29-03-2018 CWR56_RS02860 22a3b79098c32cb826737e1f466d823d 189 Pfam PF04229 GrpB protein 19 178 1.3E-39 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 7.4E-47 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 SUPERFAMILY SSF74731 3 116 7.06E-47 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 Pfam PF00453 Ribosomal protein L20 3 109 8.0E-47 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.8E-38 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.8E-38 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.8E-38 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 Gene3D G3DSA:1.10.1900.20 55 116 6.6E-29 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 68 4.0E-16 T 29-03-2018 CWR56_RS03290 26c753e136a3d0109421ce003fbba2d6 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.826 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Pfam PF14480 DNA polymerase III polC-type N-terminus I 4 75 4.0E-10 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Gene3D G3DSA:2.40.50.140 178 328 7.9E-19 T 29-03-2018 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Gene3D G3DSA:1.10.150.280 1330 1426 8.2E-4 T 29-03-2018 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Pfam PF00929 Exonuclease 419 573 1.6E-34 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Pfam PF11490 DNA polymerase III polC-type N-terminus II 91 212 8.7E-24 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 817 1240 3.0E-90 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Gene3D G3DSA:1.20.5.140 566 585 4.3E-13 T 29-03-2018 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 SMART SM00481 333 400 6.5E-25 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1432 378.924 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Pfam PF02811 PHP domain 334 689 2.0E-48 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Gene3D G3DSA:3.20.20.140 597 788 5.5E-25 T 29-03-2018 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 232 1432 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Gene3D G3DSA:3.30.420.10 413 565 1.4E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 SUPERFAMILY SSF53098 417 869 5.16E-102 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 SMART SM00479 417 582 1.5E-48 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 416 630 1.1E-40 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Gene3D G3DSA:3.20.20.150 329 412 0.0019 T 29-03-2018 CWR56_RS06060 8e178e29002872aad7b6fea477c02375 1432 Pfam PF14579 Helix-hairpin-helix motif 1343 1428 1.0E-13 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 SUPERFAMILY SSF50615 10 94 8.89E-30 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Gene3D G3DSA:1.20.150.20 373 498 5.5E-46 T 29-03-2018 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 6.4E-17 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 497 1.0E-249 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 PIRSF PIRSF039088 1 500 1.8E-252 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 2.9E-72 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 2.0E-46 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Gene3D G3DSA:2.40.30.20 3 82 1.1E-37 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 SUPERFAMILY SSF47917 372 497 7.59E-44 T 29-03-2018 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Gene3D G3DSA:3.40.50.300 83 364 6.0E-122 T 29-03-2018 CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 SUPERFAMILY SSF52540 96 370 1.95E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17295 eb46e84b1d65cf7cb40ce1095a9e178b 500 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 497 51.121 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 SUPERFAMILY SSF52402 374 519 2.35E-55 T 29-03-2018 CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 SUPERFAMILY SSF52402 168 322 2.35E-55 T 29-03-2018 CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 Pfam PF13537 Glutamine amidotransferase domain 19 114 1.2E-21 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 19 457 9.7E-88 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 PIRSF PIRSF001589 12 527 9.5E-103 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 Pfam PF00733 Asparagine synthase 209 521 4.8E-60 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 Gene3D G3DSA:3.40.50.620 171 526 2.1E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 Gene3D G3DSA:3.60.20.10 18 170 3.3E-27 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS01865 1f3d6576726ba7ed48674c704346831d 527 SUPERFAMILY SSF56235 19 172 3.6E-32 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS12390 abc1534f1a56991ad8541aba17a10e12 265 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 199 7.2E-6 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CWR56_RS12390 abc1534f1a56991ad8541aba17a10e12 265 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 7 41 1.1E-5 T 29-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal CWR56_RS13740 9520f22973c9b11a6ce7a29d9c68b7a1 291 Gene3D G3DSA:3.90.550.10 1 291 4.9E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS13740 9520f22973c9b11a6ce7a29d9c68b7a1 291 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 265 3.8E-123 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CWR56_RS13740 9520f22973c9b11a6ce7a29d9c68b7a1 291 Pfam PF00483 Nucleotidyl transferase 7 266 1.1E-31 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS13740 9520f22973c9b11a6ce7a29d9c68b7a1 291 SUPERFAMILY SSF53448 2 269 9.86E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS08830 2a25aea06b18ce4277d24fce737679de 318 Pfam PF01544 CorA-like Mg2+ transporter protein 26 316 5.0E-64 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR56_RS08830 2a25aea06b18ce4277d24fce737679de 318 SUPERFAMILY SSF143865 32 250 5.49E-24 T 29-03-2018 CWR56_RS08830 2a25aea06b18ce4277d24fce737679de 318 Gene3D G3DSA:1.20.58.340 129 249 7.0E-11 T 29-03-2018 CWR56_RS08830 2a25aea06b18ce4277d24fce737679de 318 SUPERFAMILY SSF144083 253 316 5.75E-18 T 29-03-2018 CWR56_RS08830 2a25aea06b18ce4277d24fce737679de 318 Gene3D G3DSA:1.20.58.340 250 318 2.9E-18 T 29-03-2018 CWR56_RS08830 2a25aea06b18ce4277d24fce737679de 318 Gene3D G3DSA:3.30.460.20 28 123 1.2E-10 T 29-03-2018 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 PIRSF PIRSF036426 332 444 520.0 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 PIRSF PIRSF036426 1 254 7.7E-103 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 214 8.5E-47 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 Gene3D G3DSA:3.30.950.10 128 267 3.1E-41 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 Gene3D G3DSA:3.40.50.10090 284 406 1.1E-23 T 29-03-2018 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 239 3.0E-93 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 SUPERFAMILY SSF69618 252 498 6.15E-61 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 Gene3D G3DSA:3.40.50.10090 407 499 1.1E-13 T 29-03-2018 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 Pfam PF02602 Uroporphyrinogen-III synthase HemD 266 493 5.1E-56 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 Gene3D G3DSA:3.40.1010.10 2 127 2.4E-32 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17040 b03fb46981bce536b685ec0b84f9f6ea 499 SUPERFAMILY SSF53790 1 253 7.07E-79 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS09365 547c948a0ddf0493235c6393edeceb1f 432 Gene3D G3DSA:3.40.50.1820 64 421 2.1E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS09365 547c948a0ddf0493235c6393edeceb1f 432 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 198 427 4.0E-39 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal CWR56_RS09365 547c948a0ddf0493235c6393edeceb1f 432 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 13 135 3.3E-21 T 29-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase CWR56_RS09365 547c948a0ddf0493235c6393edeceb1f 432 PIRSF PIRSF016521 1 432 2.4E-84 T 29-03-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 CWR56_RS09365 547c948a0ddf0493235c6393edeceb1f 432 SUPERFAMILY SSF53474 325 381 1.13E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS09365 547c948a0ddf0493235c6393edeceb1f 432 SUPERFAMILY SSF53474 140 259 1.13E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 Gene3D G3DSA:3.40.50.970 2 178 2.1E-49 T 29-03-2018 CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 SMART SM00861 3 167 1.7E-59 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 Pfam PF02780 Transketolase, C-terminal domain 178 298 3.4E-40 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 SUPERFAMILY SSF52922 172 306 1.7E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 Gene3D G3DSA:3.40.50.920 179 306 2.3E-46 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 Pfam PF02779 Transketolase, pyrimidine binding domain 2 165 6.8E-37 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS11535 08b7653352dd4c5ade02d6027ebf97a5 306 SUPERFAMILY SSF52518 3 168 1.07E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 Gene3D G3DSA:1.10.260.40 7 95 3.9E-17 T 29-03-2018 CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 SMART SM00530 11 66 3.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 SUPERFAMILY SSF47413 4 73 9.12E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 SUPERFAMILY SSF51182 59 181 1.19E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 Pfam PF01381 Helix-turn-helix 12 64 2.6E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 Gene3D G3DSA:2.60.120.10 96 182 2.6E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS01830 9ef3b0b5363e90d30663fcdb95ab9f85 183 Pfam PF07883 Cupin domain 126 179 7.4E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 PIRSF PIRSF001365 1 299 3.0E-86 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 Pfam PF00701 Dihydrodipicolinate synthetase family 3 288 4.8E-79 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 SMART SM01130 2 291 1.2E-102 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 SUPERFAMILY SSF51569 2 290 6.49E-89 T 29-03-2018 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 1.9E-25 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 1.9E-25 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 1.9E-25 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 1.9E-25 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 289 40.625 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 Gene3D G3DSA:3.20.20.70 1 297 6.7E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS18115 ace437f585074a9ff0fa6fa31189d909 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 289 5.7E-72 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS12350 a8bfe512930b084b28c23d941f00f97f 165 Pfam PF03073 TspO/MBR family 15 161 9.3E-40 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CWR56_RS12350 a8bfe512930b084b28c23d941f00f97f 165 PIRSF PIRSF005859 5 165 5.4E-38 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 Pfam PF00072 Response regulator receiver domain 6 114 2.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 4.4E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 SUPERFAMILY SSF52172 1 191 3.27E-41 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 Gene3D G3DSA:3.40.50.2300 1 126 5.5E-36 T 29-03-2018 CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 Gene3D G3DSA:1.10.10.10 127 232 3.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 SMART SM00448 4 114 1.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08825 a4b8976f0d88a8637ca79cb6793f71ff 232 SMART SM00862 153 229 4.2E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 SMART SM00981 58 157 8.2E-7 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 302 308 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 Gene3D G3DSA:3.40.50.150 163 382 9.8E-39 T 29-03-2018 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 SUPERFAMILY SSF53335 257 365 1.05E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 SUPERFAMILY SSF53335 146 220 1.05E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 Pfam PF01170 Putative RNA methylase family UPF0020 165 367 6.6E-58 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 198 209 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 Pfam PF02926 THUMP domain 26 157 3.6E-8 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 299 311 1.2E-5 T 29-03-2018 CWR56_RS08570 811a92b20e2b585b8896d0f0a9a1e025 382 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 196 210 1.2E-5 T 29-03-2018 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 PIRSF PIRSF000770 11 291 2.0E-45 T 29-03-2018 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 SUPERFAMILY SSF88659 193 288 1.83E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Pfam PF04542 Sigma-70 region 2 62 126 7.4E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 285 7.1E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 SUPERFAMILY SSF88946 24 129 3.4E-42 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Gene3D G3DSA:1.10.601.10 4 129 2.6E-54 T 29-03-2018 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Pfam PF00140 Sigma-70 factor, region 1.2 26 51 2.0E-8 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Gene3D G3DSA:1.10.10.10 226 296 1.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Pfam PF04539 Sigma-70 region 3 142 209 4.6E-16 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Pfam PF04545 Sigma-70, region 4 233 285 8.4E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 257 283 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 SUPERFAMILY SSF88659 135 208 6.1E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 Gene3D G3DSA:1.10.10.10 131 182 2.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 PRINTS PR00046 Major sigma-70 factor signature 110 118 5.0E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 PRINTS PR00046 Major sigma-70 factor signature 257 272 5.0E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 PRINTS PR00046 Major sigma-70 factor signature 86 99 5.0E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 PRINTS PR00046 Major sigma-70 factor signature 272 283 5.0E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07060 eb138fd927dd8ba98cb124343f62e2c6 296 PRINTS PR00046 Major sigma-70 factor signature 236 248 5.0E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS14050 cf05695f341d0e6c88d00d58b08024ab 363 Pfam PF13477 Glycosyl transferase 4-like 4 141 3.0E-38 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWR56_RS14050 cf05695f341d0e6c88d00d58b08024ab 363 Gene3D G3DSA:3.40.50.2000 172 341 2.6E-42 T 29-03-2018 CWR56_RS14050 cf05695f341d0e6c88d00d58b08024ab 363 Pfam PF00534 Glycosyl transferases group 1 168 335 6.0E-43 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CWR56_RS14050 cf05695f341d0e6c88d00d58b08024ab 363 SUPERFAMILY SSF53756 11 358 2.6E-73 T 29-03-2018 CWR56_RS14050 cf05695f341d0e6c88d00d58b08024ab 363 Gene3D G3DSA:3.40.50.2000 4 171 3.8E-8 T 29-03-2018 CWR56_RS01185 1ca60b2265d62390bad13e8d92bde874 131 Gene3D G3DSA:1.20.120.340 1 123 2.1E-36 T 29-03-2018 CWR56_RS01185 1ca60b2265d62390bad13e8d92bde874 131 PIRSF PIRSF039090 1 130 2.5E-32 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS01185 1ca60b2265d62390bad13e8d92bde874 131 Pfam PF02561 Flagellar protein FliS 7 119 1.4E-33 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS01185 1ca60b2265d62390bad13e8d92bde874 131 SUPERFAMILY SSF101116 5 124 2.75E-33 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS01185 1ca60b2265d62390bad13e8d92bde874 131 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 120 4.8E-27 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS04000 0267f1a1b9c47811fb1ff2738a82ba0e 372 Pfam PF07282 Putative transposase DNA-binding domain 291 361 7.4E-25 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS04000 0267f1a1b9c47811fb1ff2738a82ba0e 372 Pfam PF12323 Helix-turn-helix domain 5 48 1.9E-21 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CWR56_RS04000 0267f1a1b9c47811fb1ff2738a82ba0e 372 Pfam PF01385 Probable transposase 167 277 4.0E-23 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CWR56_RS04000 0267f1a1b9c47811fb1ff2738a82ba0e 372 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 245 312 2.0E-14 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS02065 f3cc96d23c9d6514fe58fef0a9e6d47f 354 Gene3D G3DSA:3.20.20.10 1 231 7.5E-24 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS02065 f3cc96d23c9d6514fe58fef0a9e6d47f 354 Pfam PF01168 Alanine racemase, N-terminal domain 7 221 1.9E-15 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS02065 f3cc96d23c9d6514fe58fef0a9e6d47f 354 SUPERFAMILY SSF51419 7 228 2.01E-25 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS15150 fe90e199152c2863efa27c57ada92bbf 376 SMART SM00382 16 176 1.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15150 fe90e199152c2863efa27c57ada92bbf 376 Gene3D G3DSA:3.40.50.300 2 261 3.5E-19 T 29-03-2018 CWR56_RS15150 fe90e199152c2863efa27c57ada92bbf 376 SUPERFAMILY SSF52540 7 155 4.09E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15150 fe90e199152c2863efa27c57ada92bbf 376 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 21 147 3.7E-8 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 113 4.4E-24 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 137 154 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 Gene3D G3DSA:3.30.360.10 129 218 2.0E-36 T 29-03-2018 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 SUPERFAMILY SSF55347 115 220 6.1E-32 T 29-03-2018 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 116 248 1.0E-44 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 249 30.611 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 Gene3D G3DSA:3.40.50.720 1 128 4.7E-21 T 29-03-2018 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 SUPERFAMILY SSF51735 220 249 1.11E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 SUPERFAMILY SSF51735 1 114 1.11E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 PIRSF PIRSF000161 1 249 1.8E-79 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16210 27e2eebf468edd784a6bf9d437860d7e 249 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 249 4.9E-64 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS15350 09036e68d705edd0b8c90d3cb110bcd0 394 Pfam PF01420 Type I restriction modification DNA specificity domain 224 375 9.0E-12 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CWR56_RS15350 09036e68d705edd0b8c90d3cb110bcd0 394 Pfam PF01420 Type I restriction modification DNA specificity domain 6 168 9.5E-10 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CWR56_RS15350 09036e68d705edd0b8c90d3cb110bcd0 394 SUPERFAMILY SSF116734 172 392 1.8E-29 T 29-03-2018 CWR56_RS15350 09036e68d705edd0b8c90d3cb110bcd0 394 Gene3D G3DSA:3.90.220.20 3 165 7.3E-25 T 29-03-2018 CWR56_RS15350 09036e68d705edd0b8c90d3cb110bcd0 394 Gene3D G3DSA:3.90.220.20 166 372 5.8E-29 T 29-03-2018 CWR56_RS15350 09036e68d705edd0b8c90d3cb110bcd0 394 SUPERFAMILY SSF116734 12 182 1.44E-27 T 29-03-2018 CWR56_RS02100 534f968c216cfaf4e7be61e53b362206 227 SMART SM00382 32 225 4.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02100 534f968c216cfaf4e7be61e53b362206 227 Gene3D G3DSA:3.40.50.300 1 226 1.9E-61 T 29-03-2018 CWR56_RS02100 534f968c216cfaf4e7be61e53b362206 227 Pfam PF00005 ABC transporter 23 169 7.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS02100 534f968c216cfaf4e7be61e53b362206 227 SUPERFAMILY SSF52540 3 223 2.34E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02100 534f968c216cfaf4e7be61e53b362206 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS12215 001b4046f78ed651c67e0b225ab480b7 371 SUPERFAMILY SSF56235 102 234 1.3E-18 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS12215 001b4046f78ed651c67e0b225ab480b7 371 Gene3D G3DSA:3.60.60.10 90 363 3.4E-34 T 29-03-2018 CWR56_RS12215 001b4046f78ed651c67e0b225ab480b7 371 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 103 333 3.7E-35 T 29-03-2018 IPR005079 Peptidase C45 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 Gene3D G3DSA:3.40.190.10 178 261 8.0E-6 T 29-03-2018 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 SUPERFAMILY SSF46785 1 84 2.35E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 SUPERFAMILY SSF53850 92 286 3.41E-26 T 29-03-2018 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 Gene3D G3DSA:3.40.190.10 88 177 4.7E-10 T 29-03-2018 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.3E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 Gene3D G3DSA:1.10.10.10 1 82 4.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS11655 3606aa4eeb72a0c19e09173f6a4881aa 290 Pfam PF03466 LysR substrate binding domain 91 284 6.4E-25 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS11695 b5e42606c209352653d6a1e87ee22fbe 105 SUPERFAMILY SSF52833 3 104 3.32E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS11695 b5e42606c209352653d6a1e87ee22fbe 105 Gene3D G3DSA:3.40.30.10 1 105 5.6E-26 T 29-03-2018 CWR56_RS11695 b5e42606c209352653d6a1e87ee22fbe 105 Pfam PF00085 Thioredoxin 4 102 4.8E-24 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR56_RS11695 b5e42606c209352653d6a1e87ee22fbe 105 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWR56_RS11695 b5e42606c209352653d6a1e87ee22fbe 105 PIRSF PIRSF000077 1 104 6.2E-25 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR56_RS13930 e6b7ba180068fae0f0e9e32ca2c8da10 554 Gene3D G3DSA:3.30.200.20 103 235 2.1E-20 T 29-03-2018 CWR56_RS13930 e6b7ba180068fae0f0e9e32ca2c8da10 554 SUPERFAMILY SSF56112 191 387 2.74E-26 T 29-03-2018 IPR011009 Protein kinase-like domain CWR56_RS13930 e6b7ba180068fae0f0e9e32ca2c8da10 554 SUPERFAMILY SSF56112 95 157 2.74E-26 T 29-03-2018 IPR011009 Protein kinase-like domain CWR56_RS13930 e6b7ba180068fae0f0e9e32ca2c8da10 554 Gene3D G3DSA:1.10.510.10 236 413 1.3E-4 T 29-03-2018 CWR56_RS13930 e6b7ba180068fae0f0e9e32ca2c8da10 554 Pfam PF03109 ABC1 family 112 229 2.1E-39 T 29-03-2018 IPR004147 UbiB domain CWR56_RS13410 2e5adcbd61b08cec665f1ec5891c445d 246 Gene3D G3DSA:3.10.20.310 35 236 0.001 T 29-03-2018 CWR56_RS13410 2e5adcbd61b08cec665f1ec5891c445d 246 Pfam PF08478 POTRA domain, FtsQ-type 36 102 5.5E-14 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type CWR56_RS16000 02998657f0ee423a571760d3abe0afc2 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 124 2.3E-50 T 29-03-2018 IPR006056 RidA family CWR56_RS16000 02998657f0ee423a571760d3abe0afc2 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 29-03-2018 IPR019897 RidA, conserved site CWR56_RS16000 02998657f0ee423a571760d3abe0afc2 125 SUPERFAMILY SSF55298 1 125 3.77E-43 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR56_RS16000 02998657f0ee423a571760d3abe0afc2 125 Gene3D G3DSA:3.30.1330.40 1 125 3.7E-43 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR56_RS16000 02998657f0ee423a571760d3abe0afc2 125 Pfam PF01042 Endoribonuclease L-PSP 9 124 1.2E-41 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 164 185 5.0E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 4 53 3.7E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 76 98 8.0E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 221 265 1.9E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 186 220 3.8E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 99 120 2.7E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 54 75 1.2E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 121 142 1.7E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:2.60.40.10 143 163 6.9E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS03955 9042bbe28b26d997627a0e38722c4f75 336 Gene3D G3DSA:1.10.10.60 280 330 3.9E-5 T 29-03-2018 CWR56_RS08205 c249b8777ad90de02a3cbf99be3e9f5f 156 Gene3D G3DSA:3.30.70.640 1 156 1.3E-66 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CWR56_RS08205 c249b8777ad90de02a3cbf99be3e9f5f 156 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 1 156 33.422 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CWR56_RS08205 c249b8777ad90de02a3cbf99be3e9f5f 156 SUPERFAMILY SSF55040 9 153 3.01E-59 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CWR56_RS08205 c249b8777ad90de02a3cbf99be3e9f5f 156 Pfam PF01967 MoaC family 13 148 4.4E-53 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CWR56_RS08205 c249b8777ad90de02a3cbf99be3e9f5f 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 2 150 2.0E-59 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 SMART SM00382 203 342 1.7E-23 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 119 607 4.3E-229 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 646 36.894 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 SUPERFAMILY SSF52540 165 410 2.44E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 Pfam PF01434 Peptidase family M41 401 606 9.0E-78 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 Gene3D G3DSA:1.10.8.60 348 415 2.1E-22 T 29-03-2018 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 338 2.1E-42 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 SUPERFAMILY SSF140990 421 612 3.92E-70 T 29-03-2018 CWR56_RS17770 1d55992304103a32c86b82fcc70434a0 664 Gene3D G3DSA:3.40.50.300 158 347 1.1E-58 T 29-03-2018 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 464 1.4E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 444 1.4E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 SUPERFAMILY SSF55785 13 113 5.58E-8 T 29-03-2018 IPR000014 PAS domain CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 Pfam PF02954 Bacterial regulatory protein, Fis family 421 461 7.8E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 Pfam PF00158 Sigma-54 interaction domain 149 315 3.0E-60 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 SUPERFAMILY SSF52540 148 383 3.47E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 SMART SM00382 169 319 3.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 SUPERFAMILY SSF46689 361 463 2.46E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 Gene3D G3DSA:3.30.450.20 8 145 1.1E-7 T 29-03-2018 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 Gene3D G3DSA:1.10.10.60 380 464 2.2E-13 T 29-03-2018 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 Gene3D G3DSA:1.10.8.60 321 379 8.8E-20 T 29-03-2018 CWR56_RS02030 cc16e639320509651a838105b8ba4ae0 466 Gene3D G3DSA:3.40.50.300 146 320 1.1E-23 T 29-03-2018 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Gene3D G3DSA:1.10.730.10 521 752 1.5E-76 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 566 6.6E-214 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Gene3D G3DSA:1.10.287.380 812 882 1.6E-23 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Gene3D G3DSA:3.90.740.10 212 240 1.9E-6 T 29-03-2018 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 866 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 819 883 2.5E-20 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 SUPERFAMILY SSF47323 579 834 5.42E-70 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 SUPERFAMILY SSF50677 195 346 5.89E-64 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 SUPERFAMILY SSF46589 819 883 1.52E-15 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Gene3D G3DSA:3.40.50.620 27 211 8.0E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Gene3D G3DSA:3.40.50.620 284 520 5.5E-76 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 SUPERFAMILY SSF52374 4 197 1.1E-146 T 29-03-2018 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 SUPERFAMILY SSF52374 345 577 1.1E-146 T 29-03-2018 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Pfam PF08264 Anticodon-binding domain of tRNA 613 761 1.3E-44 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 350 363 1.8E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 1.8E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 1.8E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 40 51 1.8E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 235 252 1.8E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS16370 0be82dcaa7bcd93b4372383b7d55183c 888 Hamap MF_02004 Valine--tRNA ligase [valS]. 6 884 15.776 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 Pfam PF00072 Response regulator receiver domain 5 113 1.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 SMART SM00862 148 225 3.6E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 SMART SM00448 2 112 4.7E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 Gene3D G3DSA:3.40.50.2300 1 117 1.1E-29 T 29-03-2018 CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 SUPERFAMILY SSF46894 124 226 2.27E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 Gene3D G3DSA:1.10.10.10 118 231 5.9E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 SUPERFAMILY SSF52172 3 118 1.17E-34 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS06890 db0f4a606eb7fbec5958d8980dc55a75 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08710 30c7ccf21a7df3a724c3c0690e77c960 200 Pfam PF03358 NADPH-dependent FMN reductase 1 132 6.9E-22 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS08710 30c7ccf21a7df3a724c3c0690e77c960 200 SUPERFAMILY SSF52218 1 187 3.88E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS08710 30c7ccf21a7df3a724c3c0690e77c960 200 Gene3D G3DSA:3.40.50.360 1 196 4.6E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 SUPERFAMILY SSF52954 283 406 7.85E-38 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 150 161 1.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 111 122 1.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 141 149 1.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 SMART SM00946 414 481 2.0E-35 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Hamap MF_01571 Proline--tRNA ligase [proS]. 12 481 45.373 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 SUPERFAMILY SSF64586 410 481 5.3E-24 T 29-03-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 107 272 1.9E-19 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 13 481 4.4E-188 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Gene3D G3DSA:3.30.110.30 412 480 6.5E-26 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 414 481 1.3E-25 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 SUPERFAMILY SSF55681 16 280 6.36E-78 T 29-03-2018 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Pfam PF03129 Anticodon binding domain 294 385 1.5E-21 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Gene3D G3DSA:3.30.930.10 11 286 1.8E-66 T 29-03-2018 CWR56_RS18975 e79d019100c80abb80bfab962120932a 481 Gene3D G3DSA:3.40.50.800 287 411 1.6E-36 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 SUPERFAMILY SSF46894 123 224 5.95E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 SMART SM00862 149 224 1.7E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 Gene3D G3DSA:1.10.10.10 126 226 2.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 Gene3D G3DSA:3.40.50.2300 1 125 2.6E-28 T 29-03-2018 CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 Pfam PF00072 Response regulator receiver domain 4 113 2.0E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 SMART SM00448 2 112 8.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 SUPERFAMILY SSF52172 1 125 6.4E-34 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS15225 cc5412972c47509d7285b968058a14cf 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 6.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS10490 bc725470362bb34ce5cf6faa8f660ce3 265 SMART SM00062 34 258 1.9E-48 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS10490 bc725470362bb34ce5cf6faa8f660ce3 265 Gene3D G3DSA:3.40.190.10 23 177 9.8E-33 T 29-03-2018 CWR56_RS10490 bc725470362bb34ce5cf6faa8f660ce3 265 Gene3D G3DSA:3.40.190.10 178 263 1.3E-8 T 29-03-2018 CWR56_RS10490 bc725470362bb34ce5cf6faa8f660ce3 265 SUPERFAMILY SSF53850 5 258 1.03E-51 T 29-03-2018 CWR56_RS10490 bc725470362bb34ce5cf6faa8f660ce3 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 256 4.1E-51 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 SUPERFAMILY SSF46894 148 212 1.22E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 SMART SM00448 4 117 1.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 Gene3D G3DSA:1.10.10.10 136 212 7.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 SMART SM00421 150 207 1.9E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 SUPERFAMILY SSF52172 3 133 1.17E-29 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 Gene3D G3DSA:3.40.50.2300 3 135 5.8E-32 T 29-03-2018 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 Pfam PF00072 Response regulator receiver domain 6 117 1.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS05875 410f7d53f4408c1c11bbb95989a1bf86 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Pfam PF07517 SecA DEAD-like domain 5 381 1.1E-130 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SUPERFAMILY SSF52540 534 629 8.21E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SUPERFAMILY SSF52540 396 502 8.21E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 355 372 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 99 113 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 318 340 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 61 85 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 392 405 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 115 125 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 PRINTS PR00906 SecA protein signature 168 188 6.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SUPERFAMILY SSF81886 631 881 4.19E-77 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SMART SM00957 4 381 3.7E-282 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Gene3D G3DSA:3.40.50.300 285 395 1.2E-9 T 29-03-2018 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Gene3D G3DSA:3.40.50.300 7 269 1.6E-56 T 29-03-2018 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SUPERFAMILY SSF52540 347 394 1.3E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SUPERFAMILY SSF52540 3 226 1.3E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SMART SM00958 226 337 5.7E-65 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Pfam PF02810 SEC-C motif 873 891 9.7E-10 T 29-03-2018 IPR004027 SEC-C motif CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 SUPERFAMILY SSF81767 225 347 4.19E-43 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Pfam PF07516 SecA Wing and Scaffold domain 628 834 7.8E-67 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Pfam PF01043 SecA preprotein cross-linking domain 230 337 2.4E-38 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 ProSitePatterns PS01312 SecA family signature. 479 494 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 837 19.844 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Gene3D G3DSA:3.40.50.300 397 631 8.1E-52 T 29-03-2018 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Gene3D G3DSA:1.10.3060.10 632 734 2.6E-29 T 29-03-2018 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 823 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS00685 23032bcb0727f2d6bac7bb9528adb267 891 Gene3D G3DSA:3.10.450.50 735 891 1.8E-45 T 29-03-2018 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 SUPERFAMILY SSF53681 104 214 2.45E-32 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 Gene3D G3DSA:3.40.50.1860 118 214 1.5E-23 T 29-03-2018 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 192 202 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 222 2.8E-57 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 Gene3D G3DSA:3.40.50.1860 1 117 2.2E-30 T 29-03-2018 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 222 2.1E-70 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CWR56_RS11180 a603cc88b3f0ebec64acd806f9fe29f8 228 SUPERFAMILY SSF53681 1 114 5.23E-37 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:1.10.10.10 2 41 0.07 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 SUPERFAMILY SSF63520 497 591 2.88E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:3.40.50.300 108 349 1.9E-22 T 29-03-2018 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 SUPERFAMILY SSF53062 600 716 1.23E-10 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:3.40.50.2300 733 836 1.4E-10 T 29-03-2018 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:3.40.930.10 841 979 2.8E-29 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Pfam PF00158 Sigma-54 interaction domain 136 301 2.7E-45 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Pfam PF03610 PTS system fructose IIA component 602 690 5.1E-6 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 890 906 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 SMART SM00382 158 308 2.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 SUPERFAMILY SSF55804 842 978 1.57E-29 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 846 978 2.1E-24 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Pfam PF00874 PRD domain 510 588 2.7E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:1.10.10.10 48 107 9.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 SUPERFAMILY SSF52540 137 377 2.28E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:1.10.1790.10 464 586 2.3E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS11570 14b156e16256d67008c0dd13a8300d3c 979 Gene3D G3DSA:3.40.50.510 587 732 1.2E-15 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 SUPERFAMILY SSF46689 234 284 2.42E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 SMART SM00342 198 281 1.2E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 Gene3D G3DSA:1.10.10.60 171 230 3.0E-16 T 29-03-2018 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 SUPERFAMILY SSF46689 182 232 7.62E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 Pfam PF12833 Helix-turn-helix domain 207 283 9.3E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 Gene3D G3DSA:1.10.10.60 231 290 3.7E-13 T 29-03-2018 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 Pfam PF02311 AraC-like ligand binding domain 27 91 1.0E-9 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 Gene3D G3DSA:2.60.120.280 4 165 1.3E-18 T 29-03-2018 CWR56_RS15645 25cf358b7824ce2296f68c58b7ec36f5 295 SUPERFAMILY SSF51215 27 92 1.7E-10 T 29-03-2018 CWR56_RS03615 7a9545d641c28c4d5fbcd1a0e50cacbf 248 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 8 57 3.1E-23 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CWR56_RS03615 7a9545d641c28c4d5fbcd1a0e50cacbf 248 Gene3D G3DSA:3.30.1330.60 68 248 9.2E-40 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS03615 7a9545d641c28c4d5fbcd1a0e50cacbf 248 SUPERFAMILY SSF103088 107 233 1.31E-31 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS03615 7a9545d641c28c4d5fbcd1a0e50cacbf 248 Pfam PF00691 OmpA family 128 227 5.7E-20 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS14455 edf29e285a54f709cf6e9393e72126c4 372 Pfam PF01385 Probable transposase 171 277 9.4E-25 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CWR56_RS14455 edf29e285a54f709cf6e9393e72126c4 372 Pfam PF07282 Putative transposase DNA-binding domain 291 361 2.7E-24 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS14455 edf29e285a54f709cf6e9393e72126c4 372 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 245 312 8.4E-14 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS14455 edf29e285a54f709cf6e9393e72126c4 372 Pfam PF12323 Helix-turn-helix domain 5 48 1.8E-21 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 8 89 4.9E-31 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 Pfam PF02378 Phosphotransferase system, EIIC 134 399 1.0E-17 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 536 552 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 124 452 1.1E-102 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 492 617 4.0E-40 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 Gene3D G3DSA:3.40.50.2300 5 101 4.7E-39 T 29-03-2018 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 SUPERFAMILY SSF55804 489 632 5.23E-39 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 SUPERFAMILY SSF52794 6 103 7.32E-37 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 490 632 4.2E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 9 97 1.6E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15365 2554435d5dbe6d00b692be221bbab792 638 Gene3D G3DSA:3.40.930.10 485 634 2.6E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS13690 7743ade815e65cdcfc4370f9a1d14f6b 454 Gene3D G3DSA:3.20.20.140 73 382 7.8E-57 T 29-03-2018 CWR56_RS13690 7743ade815e65cdcfc4370f9a1d14f6b 454 SUPERFAMILY SSF51556 60 365 2.42E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS13690 7743ade815e65cdcfc4370f9a1d14f6b 454 Pfam PF01979 Amidohydrolase family 57 412 1.8E-61 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS13690 7743ade815e65cdcfc4370f9a1d14f6b 454 SUPERFAMILY SSF51338 4 60 4.74E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS13690 7743ade815e65cdcfc4370f9a1d14f6b 454 SUPERFAMILY SSF51338 364 438 4.74E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS13690 7743ade815e65cdcfc4370f9a1d14f6b 454 Gene3D G3DSA:2.30.40.10 1 72 1.1E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 SMART SM00052 242 488 6.4E-82 T 29-03-2018 IPR001633 EAL domain CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 Gene3D G3DSA:3.30.70.270 74 240 9.1E-20 T 29-03-2018 CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 SUPERFAMILY SSF55073 89 225 9.42E-18 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 Gene3D G3DSA:3.20.20.450 241 499 3.9E-86 T 29-03-2018 IPR001633 EAL domain CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 SUPERFAMILY SSF141868 247 498 2.22E-79 T 29-03-2018 IPR001633 EAL domain CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 94 223 6.2E-13 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 Pfam PF00990 Diguanylate cyclase, GGDEF domain 85 222 1.9E-13 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14000 119be7f91ed14442a47cf1c62d88c210 515 Pfam PF00563 EAL domain 248 483 6.3E-65 T 29-03-2018 IPR001633 EAL domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Pfam PF01556 DnaJ C terminal domain 128 344 1.4E-46 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 SUPERFAMILY SSF49493 224 278 3.01E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 SUPERFAMILY SSF49493 120 176 3.01E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 SUPERFAMILY SSF57938 141 221 6.02E-19 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Gene3D G3DSA:2.10.230.10 151 208 2.9E-17 T 29-03-2018 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 SUPERFAMILY SSF49493 270 355 2.49E-25 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Gene3D G3DSA:2.60.260.20 209 265 1.4E-19 T 29-03-2018 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 SMART SM00271 5 63 4.0E-36 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Pfam PF00684 DnaJ central domain 154 218 2.6E-15 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 380 42.761 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 361 1.0E-147 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Pfam PF00226 DnaJ domain 6 68 5.7E-31 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Gene3D G3DSA:2.60.260.20 266 377 1.3E-31 T 29-03-2018 CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 Gene3D G3DSA:1.10.287.110 2 120 4.4E-39 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 ProSitePatterns PS00636 Nt-dnaJ domain signature. 48 67 - T 29-03-2018 IPR018253 DnaJ domain, conserved site CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 PRINTS PR00625 DnaJ domain signature 63 82 1.3E-33 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 PRINTS PR00625 DnaJ domain signature 43 63 1.3E-33 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 PRINTS PR00625 DnaJ domain signature 8 26 1.3E-33 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 PRINTS PR00625 DnaJ domain signature 26 41 1.3E-33 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS12435 f01c2c4ee05926a7afb070fbdbfd193d 384 SUPERFAMILY SSF46565 3 113 1.44E-39 T 29-03-2018 IPR001623 DnaJ domain CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 SUPERFAMILY SSF55031 183 340 3.38E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 Pfam PF01546 Peptidase family M20/M25/M40 82 429 7.9E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 Gene3D G3DSA:3.40.630.10 3 190 6.5E-25 T 29-03-2018 CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 15 223 1.3E-69 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 Gene3D G3DSA:3.30.70.360 203 223 0.27 T 29-03-2018 CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 Gene3D G3DSA:3.30.70.360 245 340 5.7E-14 T 29-03-2018 CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 Pfam PF07687 Peptidase dimerisation domain 229 305 1.1E-4 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 SUPERFAMILY SSF53187 2 183 1.46E-57 T 29-03-2018 CWR56_RS01490 76b30f1e09b25c7bab98b791acde2259 435 SUPERFAMILY SSF53187 351 433 1.46E-57 T 29-03-2018 CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 422 437 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 Gene3D G3DSA:3.40.50.300 317 507 2.3E-23 T 29-03-2018 CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 541 550 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 SUPERFAMILY SSF52540 337 571 4.26E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 SMART SM00382 355 499 5.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 Pfam PF00158 Sigma-54 interaction domain 338 502 3.4E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 Gene3D G3DSA:1.10.8.60 509 573 4.4E-14 T 29-03-2018 CWR56_RS15455 03d88a48f9b914d12b089e1b120b483c 669 Gene3D G3DSA:3.30.450.20 199 316 3.0E-5 T 29-03-2018 CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 SUPERFAMILY SSF55136 78 270 6.1E-37 T 29-03-2018 CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 Gene3D G3DSA:1.10.1660.10 63 128 1.6E-7 T 29-03-2018 CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 Gene3D G3DSA:1.10.1660.10 2 62 4.3E-21 T 29-03-2018 CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 SUPERFAMILY SSF46955 4 110 1.79E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 SMART SM00422 6 75 3.3E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 Pfam PF06445 GyrI-like small molecule binding domain 161 270 6.3E-6 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 Gene3D G3DSA:3.20.80.10 129 272 1.4E-13 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS07175 b5aa5385ec3183d6ea450a03d1ad2afd 272 Pfam PF13411 MerR HTH family regulatory protein 6 74 2.5E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS09125 2aab21d0ee0c61d311a2365a36921796 90 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 28 87 5.0E-8 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CWR56_RS09125 2aab21d0ee0c61d311a2365a36921796 90 Gene3D G3DSA:2.40.50.220 1 90 3.6E-31 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CWR56_RS09125 2aab21d0ee0c61d311a2365a36921796 90 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 83 8.6E-30 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CWR56_RS09125 2aab21d0ee0c61d311a2365a36921796 90 SUPERFAMILY SSF159133 1 87 3.92E-29 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CWR56_RS01910 c37b4091e5b449509a6e58ee29a1f0e6 261 Gene3D G3DSA:3.40.50.620 1 261 5.1E-80 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS01910 c37b4091e5b449509a6e58ee29a1f0e6 261 SUPERFAMILY SSF52402 1 252 1.33E-82 T 29-03-2018 CWR56_RS01910 c37b4091e5b449509a6e58ee29a1f0e6 261 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 157 177 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CWR56_RS01910 c37b4091e5b449509a6e58ee29a1f0e6 261 PIRSF PIRSF000090 1 261 9.4E-99 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CWR56_RS01910 c37b4091e5b449509a6e58ee29a1f0e6 261 SMART SM00893 22 213 8.6E-65 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS01910 c37b4091e5b449509a6e58ee29a1f0e6 261 Pfam PF01012 Electron transfer flavoprotein domain 22 208 2.0E-50 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Pfam PF04565 RNA polymerase Rpb2, domain 3 489 557 2.3E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Pfam PF04561 RNA polymerase Rpb2, domain 2 139 293 3.1E-24 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Pfam PF04560 RNA polymerase Rpb2, domain 7 1084 1159 2.7E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:2.40.270.10 765 857 1.4E-10 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:2.40.270.10 858 1068 2.0E-79 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 SUPERFAMILY SSF64484 398 1168 0.0 T 29-03-2018 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 SUPERFAMILY SSF64484 12 292 0.0 T 29-03-2018 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 ProSitePatterns PS01166 RNA polymerases beta chain signature. 935 947 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 203 909 5.9E-301 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Pfam PF10385 RNA polymerase beta subunit external 1 domain 567 635 1.3E-22 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:2.40.50.100 693 764 9.8E-27 T 29-03-2018 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Pfam PF04563 RNA polymerase beta subunit 26 475 3.5E-28 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Pfam PF00562 RNA polymerase Rpb2, domain 6 696 1082 1.9E-166 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1160 12.455 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:3.90.1800.10 1085 1128 1.3E-11 T 29-03-2018 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:3.90.1100.10 625 692 2.4E-13 T 29-03-2018 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:3.90.1100.10 18 237 4.7E-60 T 29-03-2018 CWR56_RS00050 693ab28105cbc63b444e1c1206e4d078 1238 Gene3D G3DSA:3.90.1100.10 373 624 2.7E-80 T 29-03-2018 CWR56_RS00555 dbbb9c6e66a031571b326e25c0753a53 250 SUPERFAMILY SSF52518 16 245 1.77E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS00555 dbbb9c6e66a031571b326e25c0753a53 250 Gene3D G3DSA:3.40.50.970 76 250 1.3E-34 T 29-03-2018 CWR56_RS00555 dbbb9c6e66a031571b326e25c0753a53 250 Gene3D G3DSA:3.40.50.970 5 75 1.3E-10 T 29-03-2018 CWR56_RS00555 dbbb9c6e66a031571b326e25c0753a53 250 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 196 1.2E-23 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF04122 Putative cell wall binding repeat 2 548 628 2.7E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF04122 Putative cell wall binding repeat 2 342 430 2.9E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF04122 Putative cell wall binding repeat 2 444 532 2.9E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.20.120.10 189 209 8.2E-15 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.20.120.10 270 290 4.0E-18 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.20.120.10 311 360 8.9E-15 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.20.120.10 230 250 1.7E-18 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 217 234 4.7E-4 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 277 295 3.8E-5 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 176 193 0.0024 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 238 255 3.3E-4 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 297 315 2.7E-5 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 257 273 0.0039 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF01473 Putative cell wall binding repeat 197 215 0.0014 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Pfam PF03734 L,D-transpeptidase catalytic domain 32 155 1.5E-21 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 SUPERFAMILY SSF141523 30 155 6.67E-32 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 SUPERFAMILY SSF69360 117 335 9.42E-57 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.30.30.20 251 269 5.7E-17 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.30.30.20 291 310 4.3E-18 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.30.30.20 160 188 0.0021 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.30.30.20 210 229 2.5E-16 T 29-03-2018 CWR56_RS13730 a545175ab5e00dc6f65c08d13b1662f3 644 Gene3D G3DSA:2.40.440.10 24 157 5.4E-33 T 29-03-2018 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 SUPERFAMILY SSF52540 161 428 3.67E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 333 2.9E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 Pfam PF01434 Peptidase family M41 395 601 3.0E-70 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 SUPERFAMILY SSF140990 415 603 7.85E-69 T 29-03-2018 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 Gene3D G3DSA:1.10.8.60 343 427 1.0E-21 T 29-03-2018 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 SMART SM00382 196 336 8.0E-24 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 ProSitePatterns PS00674 AAA-protein family signature. 304 322 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 111 602 4.4E-208 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 Pfam PF06480 FtsH Extracellular 14 98 3.7E-10 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 12 603 34.349 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR56_RS08815 2a0b1a2125b7fd6e079d4d9b15463f54 605 Gene3D G3DSA:3.40.50.300 150 342 1.9E-60 T 29-03-2018 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Pfam PF05043 Mga helix-turn-helix domain 91 165 1.2E-7 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 SUPERFAMILY SSF63520 293 389 1.16E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Pfam PF08279 HTH domain 9 63 2.4E-9 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Gene3D G3DSA:1.10.1790.10 279 394 1.8E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 497 627 1.4E-27 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Gene3D G3DSA:1.10.1790.10 180 275 7.9E-4 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Gene3D G3DSA:1.10.10.10 1 68 3.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Gene3D G3DSA:1.10.10.10 86 153 9.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 SUPERFAMILY SSF52794 400 483 1.1E-9 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Gene3D G3DSA:3.40.930.10 490 629 4.3E-24 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Pfam PF00874 PRD domain 305 389 4.7E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 Gene3D G3DSA:3.40.50.2300 397 486 7.7E-16 T 29-03-2018 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 SUPERFAMILY SSF55804 491 628 1.07E-26 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12580 f55d47bbb4785ec2a9fa9e42648777d8 629 SUPERFAMILY SSF46785 4 65 7.78E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08175 f1e1ff2fb0c24bc538868857e434ae15 455 Gene3D G3DSA:3.30.460.10 4 167 1.7E-17 T 29-03-2018 CWR56_RS08175 f1e1ff2fb0c24bc538868857e434ae15 455 Pfam PF04607 Region found in RelA / SpoT proteins 50 184 2.4E-18 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR56_RS08175 f1e1ff2fb0c24bc538868857e434ae15 455 SUPERFAMILY SSF81301 23 221 1.63E-26 T 29-03-2018 CWR56_RS08175 f1e1ff2fb0c24bc538868857e434ae15 455 SMART SM00954 50 186 6.9E-7 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR56_RS08175 f1e1ff2fb0c24bc538868857e434ae15 455 Gene3D G3DSA:1.10.287.860 170 219 5.9E-4 T 29-03-2018 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 281 40.599 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 Gene3D G3DSA:3.40.50.150 81 281 6.6E-50 T 29-03-2018 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 Gene3D G3DSA:1.10.8.10 1 80 5.5E-18 T 29-03-2018 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 SUPERFAMILY SSF53335 1 266 5.53E-58 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 277 1.2E-88 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 Pfam PF05175 Methyltransferase small domain 108 198 2.1E-15 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWR56_RS17375 0f95a42603cba47946070438e7d3b273 282 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 1 279 6.9E-78 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CWR56_RS11870 263998c65e410c9e4cb43020123479ff 89 Gene3D G3DSA:1.10.1220.10 29 65 7.1E-15 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWR56_RS11870 263998c65e410c9e4cb43020123479ff 89 SUPERFAMILY SSF47598 24 71 4.37E-24 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CWR56_RS11870 263998c65e410c9e4cb43020123479ff 89 Pfam PF07764 Omega Transcriptional Repressor 2 71 1.0E-45 T 29-03-2018 IPR011686 Omega transcriptional repressor CWR56_RS04555 84f99a4d00f931237e3571239fdcb036 157 Gene3D G3DSA:3.90.960.10 1 157 7.5E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS04555 84f99a4d00f931237e3571239fdcb036 157 PIRSF PIRSF006181 1 157 3.8E-59 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CWR56_RS04555 84f99a4d00f931237e3571239fdcb036 157 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 4 154 2.1E-57 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CWR56_RS04555 84f99a4d00f931237e3571239fdcb036 157 Pfam PF04073 Aminoacyl-tRNA editing domain 33 146 3.7E-21 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS04555 84f99a4d00f931237e3571239fdcb036 157 SUPERFAMILY SSF55826 4 155 2.09E-38 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 SUPERFAMILY SSF48008 96 233 5.49E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 3.2E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 Gene3D G3DSA:1.10.10.10 2 75 2.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 SUPERFAMILY SSF46785 1 75 3.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 Pfam PF07729 FCD domain 98 226 2.6E-17 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 SMART SM00345 14 73 8.1E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 Gene3D G3DSA:1.20.120.530 80 237 4.8E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 SMART SM00895 98 227 5.3E-14 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 6.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS05315 df560ac6898b0dd20678ea4398c80d9f 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 6.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS15745 3ce733f426fcbc409fdc210bf4c28f96 719 SUPERFAMILY SSF52540 229 239 1.57E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15745 3ce733f426fcbc409fdc210bf4c28f96 719 SUPERFAMILY SSF52540 1 145 1.57E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15745 3ce733f426fcbc409fdc210bf4c28f96 719 SUPERFAMILY SSF52540 595 676 1.57E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15745 3ce733f426fcbc409fdc210bf4c28f96 719 Pfam PF13476 AAA domain 5 251 2.9E-8 T 29-03-2018 CWR56_RS15745 3ce733f426fcbc409fdc210bf4c28f96 719 Gene3D G3DSA:3.40.50.300 1 343 2.3E-15 T 29-03-2018 CWR56_RS15745 3ce733f426fcbc409fdc210bf4c28f96 719 Gene3D G3DSA:3.40.50.300 373 682 0.044 T 29-03-2018 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 Pfam PF08245 Mur ligase middle domain 114 291 5.5E-36 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 SUPERFAMILY SSF53244 310 450 2.13E-42 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 Gene3D G3DSA:3.40.1190.10 98 308 3.3E-57 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 7 448 9.5E-134 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 Gene3D G3DSA:3.90.190.20 315 449 5.3E-39 T 29-03-2018 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 SUPERFAMILY SSF53623 106 308 3.01E-53 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 SUPERFAMILY SSF51984 6 96 3.66E-14 T 29-03-2018 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 Gene3D G3DSA:3.40.50.720 1 97 1.3E-13 T 29-03-2018 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 450 34.813 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS13425 96dc52318df50e32e915672014b19b97 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 384 1.7E-8 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS07540 891cb5758d16a7924ef91022023f70eb 210 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 10 195 4.6E-44 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS00925 f9fa783844f7835e49165169bf64e194 300 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 300 38.889 T 29-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CWR56_RS00925 f9fa783844f7835e49165169bf64e194 300 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 299 1.3E-101 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR56_RS00925 f9fa783844f7835e49165169bf64e194 300 PIRSF PIRSF000164 1 300 1.2E-70 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CWR56_RS00925 f9fa783844f7835e49165169bf64e194 300 Gene3D G3DSA:3.20.20.70 1 299 4.2E-56 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS00925 f9fa783844f7835e49165169bf64e194 300 SUPERFAMILY SSF51395 3 299 1.69E-78 T 29-03-2018 CWR56_RS00925 f9fa783844f7835e49165169bf64e194 300 Pfam PF01180 Dihydroorotate dehydrogenase 4 285 1.9E-65 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR56_RS06095 f4821d566f3d3627b9b0d37568688944 327 Gene3D G3DSA:3.90.1640.10 2 207 7.8E-44 T 29-03-2018 CWR56_RS06095 f4821d566f3d3627b9b0d37568688944 327 SUPERFAMILY SSF64182 19 313 8.24E-62 T 29-03-2018 CWR56_RS06095 f4821d566f3d3627b9b0d37568688944 327 Pfam PF02272 DHHA1 domain 247 323 4.5E-12 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR56_RS06095 f4821d566f3d3627b9b0d37568688944 327 Pfam PF01368 DHH family 21 165 7.0E-17 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 Gene3D G3DSA:3.40.640.10 55 261 4.9E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 Pfam PF00155 Aminotransferase class I and II 24 341 5.6E-54 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 345 50.653 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 Gene3D G3DSA:3.90.1150.10 262 346 2.9E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 208 217 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 343 1.2E-100 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CWR56_RS07345 cfc334073a81df41e25211aaa7bd7608 349 SUPERFAMILY SSF53383 21 343 5.38E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 SUPERFAMILY SSF52540 4 239 7.1E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 SMART SM00382 28 211 6.8E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 Pfam PF08402 TOBE domain 247 317 2.0E-4 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 Gene3D G3DSA:3.40.50.300 1 262 1.3E-79 T 29-03-2018 CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 Pfam PF00005 ABC transporter 19 161 1.4E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS14680 4fd6aa27ac34989ee9a57c73af4ebfda 329 SUPERFAMILY SSF50331 226 317 1.12E-6 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWR56_RS10620 17de89dbacbef5e6dd4f56bc71bad7db 78 Gene3D G3DSA:3.30.70.20 4 52 3.1E-14 T 29-03-2018 CWR56_RS10620 17de89dbacbef5e6dd4f56bc71bad7db 78 Pfam PF12838 4Fe-4S dicluster domain 15 65 4.3E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS10620 17de89dbacbef5e6dd4f56bc71bad7db 78 Gene3D G3DSA:3.30.70.20 53 78 2.0E-7 T 29-03-2018 CWR56_RS10620 17de89dbacbef5e6dd4f56bc71bad7db 78 SUPERFAMILY SSF54862 8 72 3.49E-15 T 29-03-2018 CWR56_RS10620 17de89dbacbef5e6dd4f56bc71bad7db 78 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS00545 8ffbe8cd485fa9c1cdbb70cfce8495b0 71 SUPERFAMILY SSF54862 3 69 1.5E-18 T 29-03-2018 CWR56_RS00545 8ffbe8cd485fa9c1cdbb70cfce8495b0 71 Gene3D G3DSA:3.30.70.20 52 71 1.9E-4 T 29-03-2018 CWR56_RS00545 8ffbe8cd485fa9c1cdbb70cfce8495b0 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS00545 8ffbe8cd485fa9c1cdbb70cfce8495b0 71 Gene3D G3DSA:3.30.70.20 2 51 1.2E-14 T 29-03-2018 CWR56_RS00545 8ffbe8cd485fa9c1cdbb70cfce8495b0 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS00545 8ffbe8cd485fa9c1cdbb70cfce8495b0 71 Pfam PF12838 4Fe-4S dicluster domain 12 62 5.9E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 9 22 1.1E-6 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 139 151 1.1E-6 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 301 310 1.1E-6 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 SUPERFAMILY SSF53067 108 346 1.3E-18 T 29-03-2018 CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 Gene3D G3DSA:3.30.420.40 193 328 9.1E-10 T 29-03-2018 CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 Pfam PF00814 Glycoprotease family 96 341 1.6E-14 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS05485 027e6b594933d55603926a78e7678b2b 356 Gene3D G3DSA:3.30.420.40 6 165 9.1E-8 T 29-03-2018 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 166 3.7E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 TIGRFAM TIGR00436 era: GTP-binding protein Era 5 277 1.1E-96 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 SUPERFAMILY SSF54814 180 295 8.18E-41 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 Hamap MF_00367 GTPase Era [era]. 2 294 38.246 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 74 92 1.6E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 1.6E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 Pfam PF01926 50S ribosome-binding GTPase 7 121 1.8E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 Gene3D G3DSA:3.30.300.20 196 297 3.9E-45 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 Gene3D G3DSA:3.40.50.300 1 20 0.27 T 29-03-2018 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 Gene3D G3DSA:3.40.50.300 21 195 9.1E-36 T 29-03-2018 CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 SUPERFAMILY SSF52540 7 201 3.1E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12310 8e6686d62ad9d6911b00d0e4b12bf770 297 Pfam PF07650 KH domain 205 283 3.9E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 Gene3D G3DSA:1.10.10.10 1 69 3.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 SMART SM00345 9 68 1.1E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 SMART SM00866 93 232 7.5E-23 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.7E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.7E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 Pfam PF07702 UTRA domain 96 231 6.6E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 SUPERFAMILY SSF64288 100 239 3.14E-36 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 2.4E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 SUPERFAMILY SSF46785 5 72 3.35E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15435 9886047125b2d4ba5a42c69e8c0e4c58 240 Gene3D G3DSA:3.40.1410.10 79 240 2.7E-22 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS10060 91a18a9e5b52730dc748e153b8daaa93 328 SUPERFAMILY SSF46785 7 64 4.74E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10060 91a18a9e5b52730dc748e153b8daaa93 328 Pfam PF13280 WYL domain 144 318 6.0E-15 T 29-03-2018 IPR026881 WYL domain CWR56_RS10060 91a18a9e5b52730dc748e153b8daaa93 328 Gene3D G3DSA:1.10.10.10 1 64 4.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10060 91a18a9e5b52730dc748e153b8daaa93 328 Pfam PF08279 HTH domain 11 61 3.4E-13 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Gene3D G3DSA:3.30.450.20 383 499 2.0E-4 T 29-03-2018 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Pfam PF00512 His Kinase A (phospho-acceptor) domain 659 727 1.2E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Gene3D G3DSA:3.30.565.10 734 897 1.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 777 885 1.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 SUPERFAMILY SSF55785 517 575 7.75E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 SMART SM00388 658 730 3.8E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Gene3D G3DSA:3.30.450.20 504 657 2.5E-9 T 29-03-2018 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Gene3D G3DSA:1.10.287.130 658 726 2.2E-13 T 29-03-2018 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 SMART SM00387 776 888 6.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Pfam PF13188 PAS domain 535 579 3.7E-5 T 29-03-2018 IPR000014 PAS domain CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 Gene3D G3DSA:3.30.450.20 262 382 0.021 T 29-03-2018 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 PRINTS PR00344 Bacterial sensor protein C-terminal signature 813 827 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 PRINTS PR00344 Bacterial sensor protein C-terminal signature 872 885 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 PRINTS PR00344 Bacterial sensor protein C-terminal signature 848 866 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 PRINTS PR00344 Bacterial sensor protein C-terminal signature 831 841 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 SUPERFAMILY SSF55874 719 886 1.57E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07030 6bce86c7f58bf4c5eb747c054ca4ad21 915 SUPERFAMILY SSF47384 644 729 4.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS04415 24f899e50250bf98e84ec40a5e1f3e09 501 Pfam PF08903 Domain of unknown function (DUF1846) 3 499 1.4E-236 T 29-03-2018 IPR014999 Uncharacterised protein family UPF0371 CWR56_RS04415 24f899e50250bf98e84ec40a5e1f3e09 501 Gene3D G3DSA:3.10.630.10 2 228 4.3E-105 T 29-03-2018 CWR56_RS04415 24f899e50250bf98e84ec40a5e1f3e09 501 Gene3D G3DSA:3.10.630.10 229 276 8.3E-14 T 29-03-2018 CWR56_RS04415 24f899e50250bf98e84ec40a5e1f3e09 501 Hamap MF_01567 UPF0371 protein . 1 501 56.824 T 29-03-2018 IPR014999 Uncharacterised protein family UPF0371 CWR56_RS04415 24f899e50250bf98e84ec40a5e1f3e09 501 Gene3D G3DSA:1.20.1570.10 277 338 6.8E-28 T 29-03-2018 CWR56_RS04415 24f899e50250bf98e84ec40a5e1f3e09 501 PIRSF PIRSF033132 1 501 8.7E-259 T 29-03-2018 IPR014999 Uncharacterised protein family UPF0371 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 Gene3D G3DSA:1.10.8.60 322 399 2.9E-17 T 29-03-2018 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 SUPERFAMILY SSF55785 6 105 1.4E-14 T 29-03-2018 IPR000014 PAS domain CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 362 371 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 SUPERFAMILY SSF46689 427 473 7.17E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 236 251 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 121 2.3E-15 T 29-03-2018 IPR000014 PAS domain CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 Gene3D G3DSA:1.10.10.60 417 474 4.9E-6 T 29-03-2018 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 Gene3D G3DSA:3.40.50.300 142 321 3.2E-28 T 29-03-2018 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 Gene3D G3DSA:3.30.450.20 2 121 2.0E-16 T 29-03-2018 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 SMART SM00382 169 320 1.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 Pfam PF00158 Sigma-54 interaction domain 155 317 1.5E-64 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 SMART SM00091 6 74 1.8E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 SUPERFAMILY SSF52540 155 393 7.77E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06610 cbf83284e931112f98fd8ebb1ae34cc2 476 Pfam PF13426 PAS domain 19 113 2.7E-12 T 29-03-2018 IPR000014 PAS domain CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 Pfam PF08497 Radical SAM N-terminal 5 302 2.3E-135 T 29-03-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 Gene3D G3DSA:3.40.50.280 22 189 6.9E-4 T 29-03-2018 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 5 564 3.8E-270 T 29-03-2018 IPR022946 Uncharacterised protein family UPF0313 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 Pfam PF11842 Domain of unknown function (DUF3362) 518 641 7.4E-37 T 29-03-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 5 565 52.699 T 29-03-2018 IPR022946 Uncharacterised protein family UPF0313 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 Gene3D G3DSA:3.20.20.70 203 644 3.0E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 Pfam PF04055 Radical SAM superfamily 303 509 1.2E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 SMART SM00729 299 550 1.0E-6 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 SUPERFAMILY SSF102114 302 362 5.49E-13 T 29-03-2018 CWR56_RS04535 8de5c94969c701244b45305ea076baf8 644 SUPERFAMILY SSF102114 392 575 5.49E-13 T 29-03-2018 CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 Pfam PF12673 Domain of unknown function (DUF3794) 35 115 1.0E-10 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 Pfam PF12673 Domain of unknown function (DUF3794) 184 260 1.9E-8 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 Pfam PF12673 Domain of unknown function (DUF3794) 339 420 2.0E-10 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 Pfam PF01476 LysM domain 466 507 1.2E-9 T 29-03-2018 IPR018392 LysM domain CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 Gene3D G3DSA:3.10.350.10 463 511 2.1E-10 T 29-03-2018 CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 SMART SM00257 465 509 3.5E-5 T 29-03-2018 IPR018392 LysM domain CWR56_RS17810 3f033b957e9cf6976ed4c05422a23398 516 SUPERFAMILY SSF54106 464 508 7.32E-9 T 29-03-2018 IPR018392 LysM domain CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Pfam PF16193 AAA C-terminal domain 174 252 9.9E-23 T 29-03-2018 IPR032423 AAA C-terminal domain CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 SMART SM00382 36 152 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 417 8.0E-63 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 126 3.9E-13 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Gene3D G3DSA:1.20.272.10 237 330 1.8E-33 T 29-03-2018 CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Gene3D G3DSA:3.40.50.300 1 139 4.6E-27 T 29-03-2018 CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 SUPERFAMILY SSF52540 2 219 7.1E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Gene3D G3DSA:1.10.3710.10 333 420 1.2E-24 T 29-03-2018 CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 SUPERFAMILY SSF48019 238 419 7.37E-69 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR56_RS05910 112416827e1e9b39a2d016122b1eca8e 421 Gene3D G3DSA:1.10.8.60 140 226 7.9E-19 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 PIRSF PIRSF000850 327 412 0.12 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 PIRSF PIRSF000850 404 491 21.0 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 PIRSF PIRSF000850 115 300 5.3E-5 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 SUPERFAMILY SSF56024 124 326 8.44E-52 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 Pfam PF13091 PLD-like domain 339 461 2.8E-27 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 Pfam PF13091 PLD-like domain 148 265 7.9E-13 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 SMART SM00155 233 260 5.1E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 SMART SM00155 409 436 4.4E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 SUPERFAMILY SSF56024 285 479 1.17E-49 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 Pfam PF13396 Phospholipase_D-nuclease N-terminal 21 59 1.0E-6 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 10 496 9.0E-166 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 Gene3D G3DSA:3.30.870.10 112 304 3.5E-33 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 Gene3D G3DSA:3.30.870.10 314 482 3.2E-31 T 29-03-2018 CWR56_RS00955 634617792785b296c91bc6b0b4e1194d 496 Hamap MF_01916 Cardiolipin synthase. 12 496 42.552 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CWR56_RS12560 e83d3fb8cfa23fe5c84d7e4544df7a3a 354 SUPERFAMILY SSF55920 128 353 4.84E-77 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS12560 e83d3fb8cfa23fe5c84d7e4544df7a3a 354 Gene3D G3DSA:3.90.230.10 128 353 1.3E-76 T 29-03-2018 CWR56_RS12560 e83d3fb8cfa23fe5c84d7e4544df7a3a 354 Gene3D G3DSA:3.40.350.10 1 127 1.1E-19 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS12560 e83d3fb8cfa23fe5c84d7e4544df7a3a 354 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 123 1.6E-16 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR56_RS12560 e83d3fb8cfa23fe5c84d7e4544df7a3a 354 Pfam PF00557 Metallopeptidase family M24 135 336 5.4E-66 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS12560 e83d3fb8cfa23fe5c84d7e4544df7a3a 354 SUPERFAMILY SSF53092 8 120 1.26E-19 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS17820 e6c6593d15143b92d7d1662a5ebd6da8 286 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 2 274 7.0E-64 T 29-03-2018 IPR008764 Peptidase U57, YabG CWR56_RS17820 e6c6593d15143b92d7d1662a5ebd6da8 286 Pfam PF05582 YabG peptidase U57 2 281 5.1E-114 T 29-03-2018 IPR008764 Peptidase U57, YabG CWR56_RS17820 e6c6593d15143b92d7d1662a5ebd6da8 286 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 2 282 1.0E-106 T 29-03-2018 IPR008764 Peptidase U57, YabG CWR56_RS17820 e6c6593d15143b92d7d1662a5ebd6da8 286 PIRSF PIRSF011575 1 285 4.6E-106 T 29-03-2018 IPR008764 Peptidase U57, YabG CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 SUPERFAMILY SSF46955 2 110 1.14E-20 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 Pfam PF13411 MerR HTH family regulatory protein 2 70 1.1E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 SMART SM00422 2 71 1.5E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 8.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 8.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 8.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18150 684ef8cc67d90ae989a2b229dedfab0f 264 Gene3D G3DSA:1.10.1660.10 1 158 8.9E-22 T 29-03-2018 CWR56_RS17840 038b2610d9227debc36a5a9eab9446fe 236 Pfam PF12640 UPF0489 domain 78 161 2.4E-11 T 29-03-2018 IPR024131 Uncharacterised protein family UPF0489 CWR56_RS06970 bde229e2e0013021b0b407d2518b8696 52 Pfam PF12669 Virus attachment protein p12 family 4 48 1.1E-14 T 29-03-2018 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 PIRSF PIRSF000429 1 391 3.3E-134 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 Gene3D G3DSA:3.40.47.10 265 389 2.5E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 SUPERFAMILY SSF53901 3 269 2.51E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 Gene3D G3DSA:3.40.47.10 1 147 2.0E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 Gene3D G3DSA:3.40.47.10 148 264 2.6E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 2.7E-149 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 SUPERFAMILY SSF53901 270 390 4.4E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 Pfam PF00108 Thiolase, N-terminal domain 4 261 3.8E-103 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CWR56_RS04870 399650ede047f20ca0f5b0dfbfa5b628 391 Pfam PF02803 Thiolase, C-terminal domain 270 390 2.3E-52 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CWR56_RS07915 e0d1ec01e99c82cc5a9566292ef12eb5 105 SUPERFAMILY SSF51182 10 103 2.89E-35 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS07915 e0d1ec01e99c82cc5a9566292ef12eb5 105 Gene3D G3DSA:2.60.120.10 2 102 4.1E-41 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS07915 e0d1ec01e99c82cc5a9566292ef12eb5 105 Pfam PF06865 Protein of unknown function (DUF1255) 11 102 1.3E-38 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase CWR56_RS07915 e0d1ec01e99c82cc5a9566292ef12eb5 105 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 10 103 28.506 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase CWR56_RS17590 397356e1707347287e87a3511c1dd88a 355 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 34 352 1.7E-140 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative CWR56_RS17590 397356e1707347287e87a3511c1dd88a 355 SUPERFAMILY SSF53850 41 343 1.73E-70 T 29-03-2018 CWR56_RS17590 397356e1707347287e87a3511c1dd88a 355 Gene3D G3DSA:3.40.190.10 23 156 2.0E-16 T 29-03-2018 CWR56_RS17590 397356e1707347287e87a3511c1dd88a 355 Gene3D G3DSA:3.40.190.10 157 283 2.8E-31 T 29-03-2018 CWR56_RS17590 397356e1707347287e87a3511c1dd88a 355 PIRSF PIRSF002825 1 348 1.5E-99 T 29-03-2018 IPR026045 Ferric binding protein CWR56_RS17590 397356e1707347287e87a3511c1dd88a 355 Pfam PF13343 Bacterial extracellular solute-binding protein 89 314 7.1E-31 T 29-03-2018 CWR56_RS08150 d7be5f985f4b1e7b0e8af56c26a81304 267 Pfam PF14453 ThiS-like ubiquitin 4 60 1.6E-21 T 29-03-2018 IPR032726 ThiS-like ubiquitin domain CWR56_RS08150 d7be5f985f4b1e7b0e8af56c26a81304 267 TIGRFAM TIGR02354 thiF_fam2: thiamine biosynthesis protein ThiF 66 263 2.4E-84 T 29-03-2018 IPR012729 Thiamine biosynthesis protein ThiF CWR56_RS08150 d7be5f985f4b1e7b0e8af56c26a81304 267 Gene3D G3DSA:3.40.50.720 78 266 2.2E-31 T 29-03-2018 CWR56_RS08150 d7be5f985f4b1e7b0e8af56c26a81304 267 Pfam PF00899 ThiF family 80 232 3.7E-29 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR56_RS08150 d7be5f985f4b1e7b0e8af56c26a81304 267 SUPERFAMILY SSF69572 70 266 5.36E-42 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 SUPERFAMILY SSF55073 317 474 2.67E-21 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 SUPERFAMILY SSF103190 79 178 8.37E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 SUPERFAMILY SSF141868 487 734 7.06E-82 T 29-03-2018 IPR001633 EAL domain CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Pfam PF02743 Cache domain 48 267 1.7E-15 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 463 5.3E-16 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Gene3D G3DSA:3.30.450.20 49 157 5.7E-9 T 29-03-2018 CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Gene3D G3DSA:3.30.450.20 158 271 3.3E-11 T 29-03-2018 CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Gene3D G3DSA:3.30.70.270 306 478 4.1E-28 T 29-03-2018 CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 464 1.4E-20 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 SMART SM00052 482 729 1.3E-85 T 29-03-2018 IPR001633 EAL domain CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 SMART SM00267 301 472 1.0E-10 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Pfam PF00563 EAL domain 490 724 3.1E-64 T 29-03-2018 IPR001633 EAL domain CWR56_RS07285 ac74d815e20c459f3e5b2c2ff4b32b5f 739 Gene3D G3DSA:3.20.20.450 479 733 1.7E-86 T 29-03-2018 IPR001633 EAL domain CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 5.2E-13 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 5.2E-13 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 5.2E-13 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 5.2E-13 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 Pfam PF00482 Type II secretion system (T2SS), protein F 69 192 6.6E-28 T 29-03-2018 IPR018076 Type II secretion system F domain CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 Pfam PF00482 Type II secretion system (T2SS), protein F 272 394 6.4E-23 T 29-03-2018 IPR018076 Type II secretion system F domain CWR56_RS17510 67899b75196edf69663cfa22c0ca7c36 402 Gene3D G3DSA:3.30.70.1120 98 165 0.065 T 29-03-2018 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 2 377 39.546 T 29-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 Gene3D G3DSA:3.40.50.720 77 199 1.7E-23 T 29-03-2018 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 Gene3D G3DSA:3.40.50.720 1 76 4.6E-5 T 29-03-2018 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 PRINTS PR00084 Mannitol dehydrogenase signature 151 164 3.2E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 PRINTS PR00084 Mannitol dehydrogenase signature 4 14 3.2E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 PRINTS PR00084 Mannitol dehydrogenase signature 115 128 3.2E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 PRINTS PR00084 Mannitol dehydrogenase signature 169 184 3.2E-14 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 3 123 1.6E-18 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 150 371 6.9E-58 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 SUPERFAMILY SSF51735 3 201 9.09E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 Gene3D G3DSA:1.10.1040.10 206 381 2.7E-42 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 SUPERFAMILY SSF48179 203 380 2.62E-43 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS11585 9f25a06550c9379ba16ae353d96604d9 383 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 151 163 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CWR56_RS12460 489402b3ac294232ed5ec50eb2b0396f 437 Pfam PF13520 Amino acid permease 9 419 1.1E-62 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS12460 489402b3ac294232ed5ec50eb2b0396f 437 PIRSF PIRSF006060 1 437 1.7E-77 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS04475 64456b172906d78e22774b89db459414 239 Pfam PF02811 PHP domain 7 174 1.8E-6 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS04475 64456b172906d78e22774b89db459414 239 Gene3D G3DSA:3.20.20.140 8 231 1.0E-35 T 29-03-2018 CWR56_RS04475 64456b172906d78e22774b89db459414 239 SUPERFAMILY SSF89550 6 235 6.02E-56 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS04475 64456b172906d78e22774b89db459414 239 SMART SM00481 6 80 8.2E-12 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS06100 0d58caf5c517b6a537ffc2cd2e5f174e 301 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 300 18.391 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS06100 0d58caf5c517b6a537ffc2cd2e5f174e 301 SUPERFAMILY SSF55120 1 225 7.67E-78 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS06100 0d58caf5c517b6a537ffc2cd2e5f174e 301 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 212 1.7E-75 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS06100 0d58caf5c517b6a537ffc2cd2e5f174e 301 Gene3D G3DSA:3.30.2350.10 1 222 9.6E-81 T 29-03-2018 CWR56_RS06100 0d58caf5c517b6a537ffc2cd2e5f174e 301 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 173 7.0E-55 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CWR56_RS06100 0d58caf5c517b6a537ffc2cd2e5f174e 301 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 174 232 5.6E-18 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 PIRSF PIRSF002401 1 372 4.5E-138 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 4.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 4.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 4.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 4.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 329 1.2E-137 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 SUPERFAMILY SSF102741 360 424 4.45E-18 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 Gene3D G3DSA:2.70.210.12 1 155 8.4E-54 T 29-03-2018 IPR006169 GTP1/OBG domain CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 SUPERFAMILY SSF52540 150 333 1.81E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 Gene3D G3DSA:3.40.50.300 158 340 2.2E-33 T 29-03-2018 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 Pfam PF09269 Domain of unknown function (DUF1967) 361 423 1.9E-22 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 361 424 4.3E-20 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 Hamap MF_01454 GTPase Obg [obg]. 1 330 47.506 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 Pfam PF01018 GTP1/OBG 3 157 1.1E-56 T 29-03-2018 IPR006169 GTP1/OBG domain CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 SUPERFAMILY SSF82051 2 157 5.89E-52 T 29-03-2018 IPR006169 GTP1/OBG domain CWR56_RS05290 17ca36f85a52409e62cd508e64a26296 425 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.4E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 Gene3D G3DSA:3.30.70.20 54 112 2.5E-5 T 29-03-2018 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 Pfam PF13353 4Fe-4S single cluster domain 21 204 2.5E-13 T 29-03-2018 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 SUPERFAMILY SSF54862 28 116 1.17E-7 T 29-03-2018 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 PIRSF PIRSF000371 1 311 5.1E-87 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 SUPERFAMILY SSF102114 105 283 1.44E-20 T 29-03-2018 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 Gene3D G3DSA:3.80.30.10 133 312 3.6E-36 T 29-03-2018 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 11 304 4.4E-115 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 ProSitePatterns PS01087 Radical activating enzymes signature. 22 43 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CWR56_RS00745 d6f392ea77c5d73de3646bf491431c21 316 Pfam PF04055 Radical SAM superfamily 29 245 1.0E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS05535 7414fa795ecbe83688b2c534bb3d8ef8 146 Gene3D G3DSA:3.40.630.30 44 146 2.2E-19 T 29-03-2018 CWR56_RS05535 7414fa795ecbe83688b2c534bb3d8ef8 146 Pfam PF00583 Acetyltransferase (GNAT) family 43 127 3.8E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS05535 7414fa795ecbe83688b2c534bb3d8ef8 146 SUPERFAMILY SSF55729 4 138 1.47E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS05535 7414fa795ecbe83688b2c534bb3d8ef8 146 Gene3D G3DSA:1.10.287.900 4 39 8.6E-9 T 29-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CWR56_RS17695 938b336349843bc007e8b028cff4d77c 311 Pfam PF13177 DNA polymerase III, delta subunit 9 150 2.2E-38 T 29-03-2018 CWR56_RS17695 938b336349843bc007e8b028cff4d77c 311 Gene3D G3DSA:3.40.50.300 9 137 2.0E-30 T 29-03-2018 CWR56_RS17695 938b336349843bc007e8b028cff4d77c 311 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 230 302 2.9E-5 T 29-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS17695 938b336349843bc007e8b028cff4d77c 311 SUPERFAMILY SSF52540 20 193 1.42E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17695 938b336349843bc007e8b028cff4d77c 311 Gene3D G3DSA:1.20.272.10 198 311 9.3E-17 T 29-03-2018 CWR56_RS17695 938b336349843bc007e8b028cff4d77c 311 Gene3D G3DSA:1.10.8.60 138 197 1.1E-6 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 153 167 2.7E-22 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 572 2.7E-22 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 470 2.7E-22 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 2.7E-22 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 537 556 2.7E-22 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 Gene3D G3DSA:2.70.150.10 5 202 6.0E-30 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF56784 293 316 2.19E-38 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF56784 436 579 2.19E-38 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF56784 366 400 2.19E-38 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF81653 106 201 1.57E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 Gene3D G3DSA:3.40.1110.10 245 456 3.1E-24 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 306 312 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 568 593 6.0E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 537 553 6.0E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 401 419 6.0E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 Pfam PF00122 E1-E2 ATPase 106 283 2.1E-43 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF81665 204 298 5.36E-59 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF81665 586 766 5.36E-59 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 SUPERFAMILY SSF81665 6 107 5.36E-59 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 Gene3D G3DSA:1.20.1110.10 471 781 3.3E-42 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 551 3.6E-26 T 29-03-2018 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 509 616 4.9E-26 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07910 ca3723a12721d48c430e0a0e91938157 785 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 77 484 2.4E-50 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 320 397 4.8E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 SUPERFAMILY SSF53244 319 455 1.83E-33 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Gene3D G3DSA:3.40.1190.10 96 315 4.6E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Gene3D G3DSA:3.40.1390.10 4 95 3.6E-18 T 29-03-2018 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 455 1.8E-121 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Pfam PF01225 Mur ligase family, catalytic domain 29 101 1.2E-7 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Gene3D G3DSA:3.90.190.20 319 457 1.3E-38 T 29-03-2018 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Pfam PF08245 Mur ligase middle domain 112 298 4.1E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 SUPERFAMILY SSF63418 3 103 9.29E-16 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 SUPERFAMILY SSF53623 106 318 2.49E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS13435 9ebbfdc7a2ee69a32a72687f094deaae 457 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 456 30.61 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS12635 e54bbaa58e6ae4f39af04d42e5ede7a6 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 261 9.9E-64 T 29-03-2018 IPR000150 Cof family GO:0016787 CWR56_RS12635 e54bbaa58e6ae4f39af04d42e5ede7a6 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 3.1E-69 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS12635 e54bbaa58e6ae4f39af04d42e5ede7a6 273 Gene3D G3DSA:3.40.50.1000 1 271 8.4E-43 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS12635 e54bbaa58e6ae4f39af04d42e5ede7a6 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 234 1.1E-33 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR56_RS12635 e54bbaa58e6ae4f39af04d42e5ede7a6 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 215 237 - T 29-03-2018 CWR56_RS12635 e54bbaa58e6ae4f39af04d42e5ede7a6 273 SUPERFAMILY SSF56784 1 265 4.94E-75 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14940 c291ce5141ba65ab5e39aa754a2f8a36 664 Pfam PF02687 FtsX-like permease family 89 184 4.2E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS14940 c291ce5141ba65ab5e39aa754a2f8a36 664 PIRSF PIRSF018968 1 663 1.1E-71 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 PIRSF PIRSF011572 1 258 2.2E-107 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 Pfam PF06018 CodY GAF-like domain 5 179 1.3E-58 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 Gene3D G3DSA:3.30.450.40 1 160 8.1E-23 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 SUPERFAMILY SSF46785 168 257 3.17E-41 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 Pfam PF08222 CodY helix-turn-helix domain 198 258 2.4E-34 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 6 254 3.4E-106 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 261 128.13 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWR56_RS05905 c79fef4f9009b810c0c44eb9c8d15bcd 261 Gene3D G3DSA:1.10.10.10 161 260 2.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 202.667 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 Gene3D G3DSA:3.40.440.10 153 265 3.2E-24 T 29-03-2018 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 Gene3D G3DSA:3.40.440.10 1 152 1.2E-52 T 29-03-2018 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 SUPERFAMILY SSF52540 1 428 2.97E-172 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 427 4.5E-179 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 SMART SM00788 3 423 8.6E-278 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 Pfam PF00709 Adenylosuccinate synthetase 4 422 1.8E-183 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 Gene3D G3DSA:3.90.170.10 266 429 6.2E-72 T 29-03-2018 CWR56_RS18300 329820d3ecf5fae5b4dbb609f94e338f 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR56_RS04115 57139531536bf5ff82590182d9163ff6 294 Gene3D G3DSA:3.90.850.10 40 294 6.9E-72 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR56_RS04115 57139531536bf5ff82590182d9163ff6 294 SUPERFAMILY SSF56529 70 293 5.1E-73 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR56_RS04115 57139531536bf5ff82590182d9163ff6 294 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 83 293 2.3E-63 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 Pfam PF00232 Glycosyl hydrolase family 1 3 473 1.3E-130 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 413 430 4.0E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 4.0E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 4.0E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 4.0E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 4.0E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 Gene3D G3DSA:3.20.20.80 2 476 7.0E-147 T 29-03-2018 CWR56_RS15610 29ce18e1903596cda847663e91e5c4e8 477 SUPERFAMILY SSF51445 2 474 1.46E-156 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.740 361 479 5.4E-18 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1230 1270 2.9E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1107 1147 9.9E-11 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 618 666 5.0E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 862 900 3.1E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 496 542 3.2E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 363 415 2.1E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 741 779 2.0E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 987 1030 4.7E-4 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.1120 1 84 1.3E-8 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 SUPERFAMILY SSF117074 3 76 2.75E-13 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF17210 SdrD B-like domain 6 71 3.5E-9 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 SUPERFAMILY SSF110296 894 954 5.62E-5 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 SUPERFAMILY SSF110296 642 688 5.62E-5 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 SUPERFAMILY SSF110296 786 805 5.62E-5 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 SUPERFAMILY SSF110296 1000 1040 5.62E-5 T 29-03-2018 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF01345 Domain of unknown function DUF11 741 832 4.4E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF01345 Domain of unknown function DUF11 363 452 1.8E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF01345 Domain of unknown function DUF11 493 586 1.1E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF01345 Domain of unknown function DUF11 1106 1198 9.0E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF01345 Domain of unknown function DUF11 617 701 2.4E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Pfam PF01345 Domain of unknown function DUF11 862 953 5.1E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 735 846 8.9E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.120.260 160 360 7.0E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 1099 1221 8.8E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 847 974 1.0E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 975 1098 6.6E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 480 609 4.8E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 610 734 8.8E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08900 2fd7361b2d4a6a697b524757490a3c91 1380 Gene3D G3DSA:2.60.40.10 1222 1351 1.6E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS14690 01c3db5a1e982014d6c2ee90b41780c5 222 Pfam PF01813 ATP synthase subunit D 12 204 1.5E-61 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14690 01c3db5a1e982014d6c2ee90b41780c5 222 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 210 21.956 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14690 01c3db5a1e982014d6c2ee90b41780c5 222 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 5 209 2.3E-52 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14690 01c3db5a1e982014d6c2ee90b41780c5 222 Gene3D G3DSA:1.20.5.340 3 114 0.0024 T 29-03-2018 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 Pfam PF03793 PASTA domain 598 657 1.6E-8 T 29-03-2018 IPR005543 PASTA domain CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 658 2.8E-221 T 29-03-2018 IPR011927 Stage V sporulation protein D CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 Gene3D G3DSA:3.90.1310.10 24 219 1.7E-46 T 29-03-2018 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 Gene3D G3DSA:3.40.710.10 220 605 2.3E-104 T 29-03-2018 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 SUPERFAMILY SSF56519 48 219 1.7E-43 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 SUPERFAMILY SSF56601 220 584 2.07E-100 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 SUPERFAMILY SSF54184 595 656 7.85E-5 T 29-03-2018 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 Pfam PF03717 Penicillin-binding Protein dimerisation domain 55 200 4.0E-24 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 Pfam PF00905 Penicillin binding protein transpeptidase domain 245 573 3.4E-82 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR56_RS13440 3aa3d158d3e871afa24862f5ab38977e 659 SMART SM00740 594 659 2.7E-7 T 29-03-2018 IPR005543 PASTA domain CWR56_RS18960 9f12a51f26356c04f9b7bd704a615b52 237 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 222 2.8E-75 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CWR56_RS18960 9f12a51f26356c04f9b7bd704a615b52 237 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 222 41.806 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CWR56_RS18960 9f12a51f26356c04f9b7bd704a615b52 237 SUPERFAMILY SSF53448 2 222 1.42E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS18960 9f12a51f26356c04f9b7bd704a615b52 237 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CWR56_RS18960 9f12a51f26356c04f9b7bd704a615b52 237 Gene3D G3DSA:3.90.550.10 2 231 5.9E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS18960 9f12a51f26356c04f9b7bd704a615b52 237 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 223 1.1E-69 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CWR56_RS15375 1ad8f5a29b8017a81e87cb0a457f1f9d 250 Gene3D G3DSA:3.40.50.10490 79 241 1.2E-17 T 29-03-2018 CWR56_RS15375 1ad8f5a29b8017a81e87cb0a457f1f9d 250 SUPERFAMILY SSF46689 3 71 1.79E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS15375 1ad8f5a29b8017a81e87cb0a457f1f9d 250 SUPERFAMILY SSF53697 81 246 8.9E-25 T 29-03-2018 CWR56_RS15375 1ad8f5a29b8017a81e87cb0a457f1f9d 250 Pfam PF01380 SIS domain 111 211 4.4E-14 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS15375 1ad8f5a29b8017a81e87cb0a457f1f9d 250 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 72 3.5E-11 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS15375 1ad8f5a29b8017a81e87cb0a457f1f9d 250 Gene3D G3DSA:1.10.10.10 1 78 3.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09205 2fc1ab3648cb7c56ae61659c9bce24c1 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 2.6E-39 T 29-03-2018 IPR007347 Sporulation stage V, protein S CWR56_RS09205 2fc1ab3648cb7c56ae61659c9bce24c1 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 4.0E-36 T 29-03-2018 IPR007347 Sporulation stage V, protein S CWR56_RS17445 8aafd5610ce912dc07b7a8d7a2c1a452 537 Pfam PF01943 Polysaccharide biosynthesis protein 10 314 7.8E-35 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CWR56_RS17445 8aafd5610ce912dc07b7a8d7a2c1a452 537 PIRSF PIRSF038958 5 528 1.4E-144 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CWR56_RS17445 8aafd5610ce912dc07b7a8d7a2c1a452 537 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 368 510 9.9E-25 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 SMART SM00388 245 311 3.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 1.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 1.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 SUPERFAMILY SSF47384 231 310 1.63E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 466 3.0E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 SUPERFAMILY SSF55874 300 466 1.05E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 Gene3D G3DSA:3.30.565.10 315 468 2.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 SMART SM00387 357 468 4.2E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 309 4.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS03190 45aeea05be30c884dfe59abe1cd6635e 468 Gene3D G3DSA:1.10.287.130 234 307 6.5E-14 T 29-03-2018 CWR56_RS16180 d87ee062ca199cb28dcfc08a63b4122f 84 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 27 66 2.7E-8 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CWR56_RS16180 d87ee062ca199cb28dcfc08a63b4122f 84 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 30 39 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 SUPERFAMILY SSF51735 2 244 3.31E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 8.0E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 Gene3D G3DSA:3.40.50.720 43 245 2.4E-65 T 29-03-2018 CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 Gene3D G3DSA:3.40.50.720 1 42 1.1E-7 T 29-03-2018 CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 243 1.1E-68 T 29-03-2018 CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS13030 d5dcaa601522a862b9315f1ee859447e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS09435 65bd317af2dfbe67fa410d3ac925b7ea 256 Gene3D G3DSA:1.10.3720.10 55 252 4.1E-20 T 29-03-2018 CWR56_RS09435 65bd317af2dfbe67fa410d3ac925b7ea 256 SUPERFAMILY SSF161098 60 237 1.96E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS09435 65bd317af2dfbe67fa410d3ac925b7ea 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 247 2.8E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 218 2.2E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 Gene3D G3DSA:2.40.110.10 120 218 6.5E-37 T 29-03-2018 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 Gene3D G3DSA:1.20.140.10 219 380 1.6E-63 T 29-03-2018 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.3E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 379 1.2E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 Gene3D G3DSA:1.10.540.10 1 119 5.1E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 SUPERFAMILY SSF56645 1 242 2.75E-81 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 PIRSF PIRSF016578 4 112 9.4E-7 T 29-03-2018 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 PIRSF PIRSF016578 129 379 2.9E-12 T 29-03-2018 CWR56_RS03925 1aec67cdbc7e10590729cf9565bf204d 380 SUPERFAMILY SSF47203 228 380 1.53E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS10185 6e657e4578296306edece365755514c5 493 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 100 114 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CWR56_RS10185 6e657e4578296306edece365755514c5 493 Gene3D G3DSA:3.40.50.1100 205 441 3.5E-79 T 29-03-2018 CWR56_RS10185 6e657e4578296306edece365755514c5 493 SUPERFAMILY SSF53686 1 485 2.21E-143 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS10185 6e657e4578296306edece365755514c5 493 Gene3D G3DSA:3.90.1380.10 1 87 2.1E-25 T 29-03-2018 IPR029144 Threonine synthase, N-terminal CWR56_RS10185 6e657e4578296306edece365755514c5 493 Pfam PF14821 Threonine synthase N terminus 3 78 1.2E-21 T 29-03-2018 IPR029144 Threonine synthase, N-terminal CWR56_RS10185 6e657e4578296306edece365755514c5 493 Gene3D G3DSA:3.40.50.1100 104 204 6.9E-15 T 29-03-2018 CWR56_RS10185 6e657e4578296306edece365755514c5 493 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 422 9.1E-14 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS10185 6e657e4578296306edece365755514c5 493 TIGRFAM TIGR00260 thrC: threonine synthase 80 433 1.3E-75 T 29-03-2018 IPR004450 Threonine synthase-like CWR56_RS13560 73ea9cd32b6054bc754eaf31e0b0a513 308 Gene3D G3DSA:3.40.33.10 177 306 4.6E-22 T 29-03-2018 IPR014044 CAP domain CWR56_RS13560 73ea9cd32b6054bc754eaf31e0b0a513 308 SMART SM00198 184 308 0.0094 T 29-03-2018 IPR014044 CAP domain CWR56_RS13560 73ea9cd32b6054bc754eaf31e0b0a513 308 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 183 307 8.9E-59 T 29-03-2018 IPR014258 CAP domain, YkwD-like CWR56_RS13560 73ea9cd32b6054bc754eaf31e0b0a513 308 Pfam PF00188 Cysteine-rich secretory protein family 191 306 4.6E-23 T 29-03-2018 IPR014044 CAP domain CWR56_RS13560 73ea9cd32b6054bc754eaf31e0b0a513 308 SUPERFAMILY SSF55797 183 306 1.96E-30 T 29-03-2018 IPR014044 CAP domain CWR56_RS13855 8719f7185ac9d9c194072b4095e3c40e 388 Pfam PF00155 Aminotransferase class I and II 58 383 4.6E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS13855 8719f7185ac9d9c194072b4095e3c40e 388 SUPERFAMILY SSF53383 1 387 7.8E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS13855 8719f7185ac9d9c194072b4095e3c40e 388 Gene3D G3DSA:3.90.1150.10 2 80 7.6E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS13855 8719f7185ac9d9c194072b4095e3c40e 388 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 387 4.9E-149 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR56_RS13855 8719f7185ac9d9c194072b4095e3c40e 388 Gene3D G3DSA:3.40.640.10 81 281 1.7E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS13855 8719f7185ac9d9c194072b4095e3c40e 388 Gene3D G3DSA:3.90.1150.10 282 388 3.0E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 Pfam PF00800 Prephenate dehydratase 129 306 6.4E-58 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 343 350 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 Gene3D G3DSA:3.40.190.10 133 214 3.7E-24 T 29-03-2018 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 Gene3D G3DSA:1.20.59.10 1 132 3.1E-23 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 PIRSF PIRSF001500 1 397 1.7E-102 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 Gene3D G3DSA:3.40.190.10 215 294 1.6E-24 T 29-03-2018 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 SUPERFAMILY SSF53850 129 310 2.28E-53 T 29-03-2018 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 5 84 7.0E-21 T 29-03-2018 IPR011279 Chorismate mutase, Gram-positive CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 SUPERFAMILY SSF55021 300 395 6.22E-25 T 29-03-2018 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 SUPERFAMILY SSF48600 1 87 4.12E-19 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 281 303 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 Gene3D G3DSA:3.30.70.260 308 398 5.6E-28 T 29-03-2018 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 Pfam PF01817 Chorismate mutase type II 8 85 1.0E-17 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR56_RS08860 6bf8252c4b1dd4508a3cb813809afc6f 398 SMART SM00830 8 87 3.0E-23 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR56_RS09495 9d9c27968d571a652e0b5c68db9db38b 161 Gene3D G3DSA:2.40.50.110 74 158 2.0E-9 T 29-03-2018 CWR56_RS09495 9d9c27968d571a652e0b5c68db9db38b 161 Gene3D G3DSA:2.40.50.110 8 73 4.4E-9 T 29-03-2018 CWR56_RS09495 9d9c27968d571a652e0b5c68db9db38b 161 Pfam PF08239 Bacterial SH3 domain 23 72 1.3E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS09495 9d9c27968d571a652e0b5c68db9db38b 161 Pfam PF08239 Bacterial SH3 domain 103 156 6.5E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS09495 9d9c27968d571a652e0b5c68db9db38b 161 SMART SM00287 12 75 0.45 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS09495 9d9c27968d571a652e0b5c68db9db38b 161 SMART SM00287 93 154 0.62 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 3.5E-33 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 SMART SM00363 98 160 3.7E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 Gene3D G3DSA:3.10.290.10 104 148 8.6E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 SUPERFAMILY SSF55174 3 207 2.62E-67 T 29-03-2018 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 Gene3D G3DSA:1.10.1050.10 1 103 2.2E-42 T 29-03-2018 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 SMART SM01390 3 97 1.1E-55 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 35.254 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 5.6E-75 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 Gene3D G3DSA:1.10.1050.10 149 207 2.8E-14 T 29-03-2018 CWR56_RS00225 0634ecd4201e4fe56f2847ab69f3d08f 207 Pfam PF01479 S4 domain 98 145 2.0E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS13325 f56d2137489ede6dbd5051ee8ed99aac 445 SUPERFAMILY SSF50156 14 104 3.33E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS13325 f56d2137489ede6dbd5051ee8ed99aac 445 SUPERFAMILY SSF102114 96 243 1.57E-11 T 29-03-2018 CWR56_RS13325 f56d2137489ede6dbd5051ee8ed99aac 445 Gene3D G3DSA:2.30.42.10 3 90 4.9E-7 T 29-03-2018 CWR56_RS13325 f56d2137489ede6dbd5051ee8ed99aac 445 Gene3D G3DSA:3.80.30.10 126 275 1.1E-13 T 29-03-2018 CWR56_RS13325 f56d2137489ede6dbd5051ee8ed99aac 445 Pfam PF04459 Protein of unknown function (DUF512) 229 432 1.2E-73 T 29-03-2018 IPR007549 Domain of unknown function DUF512 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 PIRSF PIRSF010376 2 291 1.1E-92 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 Gene3D G3DSA:3.30.70.890 163 292 6.2E-25 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 SUPERFAMILY SSF54211 4 157 6.22E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 282 34.014 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 Pfam PF00288 GHMP kinases N terminal domain 88 144 1.6E-9 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 280 5.6E-88 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 Pfam PF08544 GHMP kinases C terminal 200 274 2.4E-8 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 PRINTS PR00958 Homoserine kinase signature 243 258 2.2E-7 T 29-03-2018 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 PRINTS PR00958 Homoserine kinase signature 170 187 2.2E-7 T 29-03-2018 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 PRINTS PR00958 Homoserine kinase signature 8 23 2.2E-7 T 29-03-2018 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 PRINTS PR00958 Homoserine kinase signature 104 119 2.2E-7 T 29-03-2018 CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 Gene3D G3DSA:3.30.230.10 4 160 6.1E-48 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS17805 d8b2f5715bb7bce17b377711cf861005 296 SUPERFAMILY SSF55060 166 282 5.76E-24 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR56_RS00260 f5f27e6ef6dcdb016457813f078348ad 143 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 29.305 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00260 f5f27e6ef6dcdb016457813f078348ad 143 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 2.7E-63 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00260 f5f27e6ef6dcdb016457813f078348ad 143 PIRSF PIRSF002181 1 143 1.0E-53 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00260 f5f27e6ef6dcdb016457813f078348ad 143 Pfam PF00572 Ribosomal protein L13 14 138 8.7E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00260 f5f27e6ef6dcdb016457813f078348ad 143 SUPERFAMILY SSF52161 1 140 6.8E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00260 f5f27e6ef6dcdb016457813f078348ad 143 Gene3D G3DSA:3.90.1180.10 1 143 1.0E-64 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Pfam PF13643 Domain of unknown function (DUF4145) 22 111 7.1E-11 T 29-03-2018 IPR025285 Domain of unknown function DUF4145 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Gene3D G3DSA:3.40.50.300 577 974 8.0E-12 T 29-03-2018 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 152 306 6.9E-8 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Pfam PF00271 Helicase conserved C-terminal domain 605 708 2.3E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Pfam PF04851 Type III restriction enzyme, res subunit 339 498 6.8E-37 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 SUPERFAMILY SSF52540 580 754 1.17E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 SUPERFAMILY SSF52540 457 495 1.17E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Gene3D G3DSA:3.40.50.300 142 518 7.6E-28 T 29-03-2018 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 Pfam PF08463 EcoEI R protein C-terminal 958 1102 2.2E-17 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 SMART SM00487 336 523 9.4E-18 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS15330 42eb66925524c15533df63bf3fdde605 1111 SUPERFAMILY SSF52540 302 555 3.98E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 3 210 2.2E-58 T 29-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 151 206 7.5E-12 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 SUPERFAMILY SSF63999 1 130 1.31E-39 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 SUPERFAMILY SSF63862 151 211 3.14E-9 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 SMART SM00983 149 208 5.8E-15 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 Gene3D G3DSA:3.40.50.10240 1 120 3.2E-37 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 Gene3D G3DSA:2.60.120.320 121 212 9.0E-19 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS13015 f63062036bbf6f8eb64975d68493298a 213 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 27 125 4.5E-30 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 PRINTS PR00050 Cold shock protein signature 24 33 8.0E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 PRINTS PR00050 Cold shock protein signature 4 19 8.0E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 PRINTS PR00050 Cold shock protein signature 39 57 8.0E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 Gene3D G3DSA:2.40.50.140 1 66 4.5E-28 T 29-03-2018 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 PIRSF PIRSF002599 1 66 1.7E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 8.1E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 SUPERFAMILY SSF50249 1 65 2.0E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 SMART SM00357 3 66 3.3E-28 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS06300 c2de0c7962b501ac4e28ae120ffe3c17 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CWR56_RS07940 ad781427f0dd0b5dfea456e58ec2e641 320 Gene3D G3DSA:3.40.50.1100 23 146 1.2E-28 T 29-03-2018 CWR56_RS07940 ad781427f0dd0b5dfea456e58ec2e641 320 SUPERFAMILY SSF53686 1 317 3.14E-81 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS07940 ad781427f0dd0b5dfea456e58ec2e641 320 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 305 5.3E-58 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS07940 ad781427f0dd0b5dfea456e58ec2e641 320 Gene3D G3DSA:3.40.50.1100 147 320 8.1E-42 T 29-03-2018 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 SUPERFAMILY SSF47384 437 517 1.35E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 SMART SM00388 453 520 5.3E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 Pfam PF00512 His Kinase A (phospho-acceptor) domain 454 518 7.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 Gene3D G3DSA:3.30.565.10 523 673 2.1E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 568 671 7.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 Gene3D G3DSA:1.10.287.130 443 515 7.4E-9 T 29-03-2018 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 Gene3D G3DSA:2.60.120.260 53 221 1.4E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 SUPERFAMILY SSF55874 528 670 2.36E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 9.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 671 9.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 652 9.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 629 9.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16425 3e74aa501cf802ed2a46f187f129e096 675 SMART SM00387 564 674 3.2E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02685 cab5d428c3eb5748eb7c32f944db3fcd 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR56_RS02685 cab5d428c3eb5748eb7c32f944db3fcd 486 SUPERFAMILY SSF53720 10 482 2.23E-150 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS02685 cab5d428c3eb5748eb7c32f944db3fcd 486 Pfam PF00171 Aldehyde dehydrogenase family 20 479 2.7E-160 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS02685 cab5d428c3eb5748eb7c32f944db3fcd 486 Gene3D G3DSA:3.40.605.10 1 274 2.9E-87 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS02685 cab5d428c3eb5748eb7c32f944db3fcd 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR56_RS02685 cab5d428c3eb5748eb7c32f944db3fcd 486 Gene3D G3DSA:3.40.309.10 275 464 3.5E-64 T 29-03-2018 CWR56_RS15580 586300f8b118b03ef1df25037df80f83 395 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 7 386 6.2E-105 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CWR56_RS15580 586300f8b118b03ef1df25037df80f83 395 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 227 368 4.3E-20 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CWR56_RS15580 586300f8b118b03ef1df25037df80f83 395 Gene3D G3DSA:3.40.50.2000 231 374 6.9E-35 T 29-03-2018 CWR56_RS15580 586300f8b118b03ef1df25037df80f83 395 SUPERFAMILY SSF53756 1 387 2.32E-75 T 29-03-2018 CWR56_RS15580 586300f8b118b03ef1df25037df80f83 395 Gene3D G3DSA:3.40.50.2000 3 230 6.1E-28 T 29-03-2018 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 Pfam PF00390 Malic enzyme, N-terminal domain 23 151 1.1E-28 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 SMART SM01274 18 151 1.2E-82 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 SUPERFAMILY SSF53223 13 161 6.83E-54 T 29-03-2018 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 SUPERFAMILY SSF51735 163 393 1.17E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 PIRSF PIRSF000106 18 394 3.2E-81 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 Gene3D G3DSA:3.40.50.10380 6 160 1.2E-39 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 Pfam PF03949 Malic enzyme, NAD binding domain 165 386 2.9E-25 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 Gene3D G3DSA:3.40.50.720 161 394 7.6E-75 T 29-03-2018 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 SMART SM00919 163 387 2.6E-119 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CWR56_RS04570 216f63ecba01b1fbf8d499360d4bd445 394 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 142 1.8E-20 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 305 317 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 Gene3D G3DSA:3.90.230.10 142 378 2.3E-56 T 29-03-2018 CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 Pfam PF00557 Metallopeptidase family M24 152 357 1.9E-39 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 Gene3D G3DSA:3.40.350.10 2 141 5.9E-16 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 SUPERFAMILY SSF53092 6 141 7.15E-24 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS13300 4ec6b1d99dc4f2bca3675af4b2ccf3c0 379 SUPERFAMILY SSF55920 140 374 5.1E-61 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Pfam PF03461 TRCF domain 1016 1097 3.3E-25 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SMART SM00982 1015 1113 2.5E-33 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SMART SM00487 612 802 3.6E-38 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Pfam PF02559 CarD-like/TRCF domain 492 587 6.1E-30 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 43 1120 28.61 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SUPERFAMILY SSF52540 368 470 1.58E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Gene3D G3DSA:3.40.50.300 232 801 2.0E-40 T 29-03-2018 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SUPERFAMILY SSF141259 483 560 2.09E-22 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1088 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SUPERFAMILY SSF52540 664 935 1.31E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SMART SM00490 838 922 3.8E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Gene3D G3DSA:3.40.50.300 802 968 3.1E-29 T 29-03-2018 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SUPERFAMILY SSF52540 15 360 4.25E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Pfam PF00270 DEAD/DEAH box helicase 618 776 2.6E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SUPERFAMILY SSF143517 1000 1107 3.27E-32 T 29-03-2018 CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 Pfam PF00271 Helicase conserved C-terminal domain 817 921 9.1E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS17460 0d4c00c21009a9a8601443bb84b8a3c0 1128 SMART SM01058 491 588 3.2E-43 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 415 6.3E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 185 5.8E-61 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 PIRSF PIRSF500134 1 431 8.0E-175 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 412 6.0E-132 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 SMART SM00984 314 416 1.4E-42 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 SUPERFAMILY SSF48179 200 295 9.35E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 200 291 1.6E-36 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 SUPERFAMILY SSF52413 303 427 4.19E-34 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 PIRSF PIRSF000124 1 431 2.1E-141 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 Gene3D G3DSA:3.40.50.720 223 428 1.4E-71 T 29-03-2018 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 Gene3D G3DSA:3.40.50.720 1 201 2.2E-54 T 29-03-2018 CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 SUPERFAMILY SSF51735 1 194 5.07E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS14055 0fed62da57ff2765d543ad087eb81eed 431 Gene3D G3DSA:1.20.5.100 202 222 1.1E-14 T 29-03-2018 CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 SUPERFAMILY SSF53187 5 175 1.07E-53 T 29-03-2018 CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 SUPERFAMILY SSF53187 310 392 1.07E-53 T 29-03-2018 CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 Gene3D G3DSA:3.40.630.10 2 266 3.0E-60 T 29-03-2018 CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 Gene3D G3DSA:3.40.630.10 267 394 4.9E-6 T 29-03-2018 CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 SUPERFAMILY SSF55031 180 277 1.31E-16 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 Pfam PF01546 Peptidase family M20/M25/M40 68 390 3.1E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 Pfam PF07687 Peptidase dimerisation domain 172 279 1.1E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15980 49eae8b8f630b31da42f39d33090798a 395 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR56_RS06350 e2ac12a7063b9414473a5be32d8a1800 142 Pfam PF09393 Phage tail tube protein 3 140 6.4E-53 T 29-03-2018 IPR018989 Phage tail tube protein CWR56_RS06350 e2ac12a7063b9414473a5be32d8a1800 142 SUPERFAMILY SSF69279 6 142 4.08E-45 T 29-03-2018 CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 Gene3D G3DSA:1.10.10.10 143 187 3.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 PIRSF PIRSF036382 1 191 2.1E-65 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 Pfam PF00072 Response regulator receiver domain 5 114 3.4E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 Pfam PF03861 ANTAR domain 134 186 2.1E-18 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 SMART SM01012 131 186 1.1E-20 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 Gene3D G3DSA:3.40.50.2300 1 142 3.3E-32 T 29-03-2018 CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 SMART SM00448 3 115 1.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09065 89676973b7e12dccde532c02522d4512 191 SUPERFAMILY SSF52172 2 186 5.69E-51 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS09075 70f44e337f3260c21ee4fa284513b0ba 477 PIRSF PIRSF012293 1 477 7.7E-209 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA CWR56_RS09075 70f44e337f3260c21ee4fa284513b0ba 477 SUPERFAMILY SSF53067 7 31 5.08E-9 T 29-03-2018 CWR56_RS09075 70f44e337f3260c21ee4fa284513b0ba 477 SUPERFAMILY SSF53067 60 318 5.08E-9 T 29-03-2018 CWR56_RS09075 70f44e337f3260c21ee4fa284513b0ba 477 Pfam PF06277 Ethanolamine utilisation protein EutA 3 477 4.9E-219 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA CWR56_RS09075 70f44e337f3260c21ee4fa284513b0ba 477 Gene3D G3DSA:3.30.420.40 5 182 4.6E-12 T 29-03-2018 CWR56_RS12050 5fbb358d9a8c35480547733e585aeaf0 200 SUPERFAMILY SSF47090 125 192 1.05E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like CWR56_RS12050 5fbb358d9a8c35480547733e585aeaf0 200 Pfam PF01471 Putative peptidoglycan binding domain 136 191 1.3E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CWR56_RS12050 5fbb358d9a8c35480547733e585aeaf0 200 Gene3D G3DSA:1.10.101.10 118 198 2.0E-22 T 29-03-2018 IPR002477 Peptidoglycan binding-like CWR56_RS12265 23de3a4ae269a073fde69fb45daac540 65 Gene3D G3DSA:3.30.70.20 45 64 2.5E-6 T 29-03-2018 CWR56_RS12265 23de3a4ae269a073fde69fb45daac540 65 Gene3D G3DSA:3.30.70.20 2 44 1.8E-10 T 29-03-2018 CWR56_RS12265 23de3a4ae269a073fde69fb45daac540 65 SUPERFAMILY SSF54862 3 59 6.02E-15 T 29-03-2018 CWR56_RS12265 23de3a4ae269a073fde69fb45daac540 65 Pfam PF12838 4Fe-4S dicluster domain 10 58 1.8E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS12265 23de3a4ae269a073fde69fb45daac540 65 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16930 cb4408d998d4604c81b845661ed84847 237 Pfam PF02811 PHP domain 6 179 2.7E-11 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS16930 cb4408d998d4604c81b845661ed84847 237 SMART SM00481 5 83 1.8E-11 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS16930 cb4408d998d4604c81b845661ed84847 237 Gene3D G3DSA:3.20.20.140 5 236 1.3E-35 T 29-03-2018 CWR56_RS16930 cb4408d998d4604c81b845661ed84847 237 SUPERFAMILY SSF89550 4 232 4.58E-43 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS09060 29f9021eee7dcea8a0a6c3803f933e99 149 Gene3D G3DSA:3.40.50.300 2 147 6.2E-13 T 29-03-2018 CWR56_RS09060 29f9021eee7dcea8a0a6c3803f933e99 149 SUPERFAMILY SSF52540 3 143 3.86E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09060 29f9021eee7dcea8a0a6c3803f933e99 149 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 142 7.8E-63 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CWR56_RS09060 29f9021eee7dcea8a0a6c3803f933e99 149 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 142 9.5E-59 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CWR56_RS09060 29f9021eee7dcea8a0a6c3803f933e99 149 PIRSF PIRSF036409 1 145 1.8E-58 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CWR56_RS06310 9523084cf1e6cdb34576776280ed72f3 251 Gene3D G3DSA:3.10.50.40 105 229 4.8E-42 T 29-03-2018 CWR56_RS06310 9523084cf1e6cdb34576776280ed72f3 251 SUPERFAMILY SSF109998 4 142 5.49E-16 T 29-03-2018 IPR027304 Trigger factor/SurA domain CWR56_RS06310 9523084cf1e6cdb34576776280ed72f3 251 SUPERFAMILY SSF54534 106 203 1.27E-33 T 29-03-2018 CWR56_RS06310 9523084cf1e6cdb34576776280ed72f3 251 Pfam PF00639 PPIC-type PPIASE domain 123 203 5.8E-26 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CWR56_RS06310 9523084cf1e6cdb34576776280ed72f3 251 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 143 163 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 Gene3D G3DSA:3.30.70.980 80 175 1.7E-33 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 Gene3D G3DSA:1.10.10.200 20 73 5.6E-25 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 Gene3D G3DSA:3.30.70.980 176 239 6.5E-9 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 SUPERFAMILY SSF75625 5 238 1.27E-91 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 2 238 33.547 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 4 237 5.0E-91 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR56_RS03885 677fdda23502a7da6d7aa089f6e03e45 239 Pfam PF01709 Transcriptional regulator 6 236 5.0E-95 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 1.3E-35 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 PIRSF PIRSF000447 1 412 9.5E-184 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 Gene3D G3DSA:3.40.47.10 262 412 2.5E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 Gene3D G3DSA:3.40.47.10 5 259 3.6E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 4.3E-64 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 SUPERFAMILY SSF53901 2 251 8.93E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 SUPERFAMILY SSF53901 213 411 3.15E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 SMART SM00825 Beta-ketoacyl synthase 5 412 1.1E-14 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CWR56_RS05395 d1ae0961994c749dc014aace09ff43ee 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 409 2.3E-198 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 240 5.1E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 Pfam PF00072 Response regulator receiver domain 17 127 3.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 Gene3D G3DSA:3.40.50.2300 14 138 9.3E-32 T 29-03-2018 CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 SMART SM00448 15 127 5.4E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 SMART SM00862 164 240 3.0E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 SUPERFAMILY SSF52172 16 199 3.69E-36 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS08580 15ad16909f33123f130c969b6bebb674 244 Gene3D G3DSA:1.10.10.10 139 244 1.7E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02270 60edf6535337bc6e90d7c53a1948b424 135 Pfam PF03610 PTS system fructose IIA component 3 116 7.7E-27 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS02270 60edf6535337bc6e90d7c53a1948b424 135 SUPERFAMILY SSF53062 1 132 2.49E-36 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS02270 60edf6535337bc6e90d7c53a1948b424 135 Gene3D G3DSA:3.40.50.510 1 134 3.5E-33 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 Gene3D G3DSA:3.40.50.300 1 180 3.1E-23 T 29-03-2018 CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 SUPERFAMILY SSF52540 348 510 3.06E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 SUPERFAMILY SSF52540 291 319 3.06E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 SUPERFAMILY SSF52540 2 204 3.06E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 Pfam PF13476 AAA domain 5 208 1.3E-12 T 29-03-2018 CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 PIRSF PIRSF003128 1 558 2.8E-175 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 554 1.4E-163 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CWR56_RS05520 a60819b6dc4bf6977281745be39aa2df 559 Gene3D G3DSA:3.40.50.300 181 535 1.1E-18 T 29-03-2018 CWR56_RS08875 385fd55becde8daad30fdd18f83f380b 279 Gene3D G3DSA:3.40.50.720 1 170 4.3E-25 T 29-03-2018 CWR56_RS08875 385fd55becde8daad30fdd18f83f380b 279 SUPERFAMILY SSF48179 173 277 3.06E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS08875 385fd55becde8daad30fdd18f83f380b 279 Pfam PF02153 Prephenate dehydrogenase 15 268 1.1E-57 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CWR56_RS08875 385fd55becde8daad30fdd18f83f380b 279 SUPERFAMILY SSF51735 2 166 2.93E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS08875 385fd55becde8daad30fdd18f83f380b 279 Gene3D G3DSA:1.10.3660.10 180 278 3.8E-16 T 29-03-2018 CWR56_RS16265 8445397aa377ffe633c2c10bf3af598d 293 Pfam PF01925 Sulfite exporter TauE/SafE 4 149 7.5E-11 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 Pfam PF09190 DALR domain 353 411 1.8E-14 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 1.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 1.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 1.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 1.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 464 8.1E-184 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 465 39.557 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 SUPERFAMILY SSF47323 314 464 3.79E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 Gene3D G3DSA:1.20.120.640 304 405 8.5E-20 T 29-03-2018 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 SUPERFAMILY SSF52374 2 310 1.69E-102 T 29-03-2018 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 SMART SM00840 353 416 2.7E-18 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 Gene3D G3DSA:3.40.50.620 1 303 3.8E-97 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS18990 aaa046cfb76f97e906b14cce10c44013 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 14 311 2.3E-136 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 Pfam PF00772 DnaB-like helicase N terminal domain 9 108 1.4E-29 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 Gene3D G3DSA:3.40.50.300 172 436 1.2E-34 T 29-03-2018 CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 Pfam PF03796 DnaB-like helicase C terminal domain 172 436 8.9E-44 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 SUPERFAMILY SSF52540 171 376 2.54E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 SUPERFAMILY SSF52540 404 430 2.54E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 SUPERFAMILY SSF48024 7 116 3.79E-30 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR56_RS15780 5b939706e89cb39133e3afca48e45fae 444 Gene3D G3DSA:1.10.860.10 2 149 1.0E-30 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 193 200 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 SUPERFAMILY SSF46609 29 120 6.81E-35 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 PRINTS PR01703 Manganese superoxide dismutase signature 154 162 2.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 PRINTS PR01703 Manganese superoxide dismutase signature 102 115 2.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 PRINTS PR01703 Manganese superoxide dismutase signature 191 203 2.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 PRINTS PR01703 Manganese superoxide dismutase signature 35 46 2.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 PRINTS PR01703 Manganese superoxide dismutase signature 56 69 2.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 31 118 3.0E-26 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 PIRSF PIRSF000349 6 234 5.2E-83 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 SUPERFAMILY SSF54719 121 231 4.71E-45 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 Gene3D G3DSA:1.10.287.990 49 119 5.8E-29 T 29-03-2018 CWR56_RS07755 2dee7886bb87888c5f52683389c3a4c2 234 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 125 223 4.1E-42 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR56_RS15890 4f6193ca96b939f34e5fabe1f0438c8e 120 Gene3D G3DSA:1.10.10.10 15 115 4.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15890 4f6193ca96b939f34e5fabe1f0438c8e 120 SUPERFAMILY SSF46785 6 101 2.08E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15890 4f6193ca96b939f34e5fabe1f0438c8e 120 Pfam PF01638 HxlR-like helix-turn-helix 18 103 1.1E-19 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS01350 18fc34fab63894c31c659ade83118812 338 Pfam PF00448 SRP54-type protein, GTPase domain 146 333 2.5E-44 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS01350 18fc34fab63894c31c659ade83118812 338 Gene3D G3DSA:3.40.50.300 143 322 2.5E-23 T 29-03-2018 CWR56_RS01350 18fc34fab63894c31c659ade83118812 338 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 59 230 4.4E-55 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CWR56_RS01350 18fc34fab63894c31c659ade83118812 338 SMART SM00962 143 334 1.9E-62 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR56_RS01350 18fc34fab63894c31c659ade83118812 338 SUPERFAMILY SSF52540 145 334 4.35E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01350 18fc34fab63894c31c659ade83118812 338 SMART SM00382 142 261 1.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06860 3b01522dbfb9d940b31f851fe04b9e08 191 SUPERFAMILY SSF52218 1 189 5.5E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS06860 3b01522dbfb9d940b31f851fe04b9e08 191 Pfam PF03358 NADPH-dependent FMN reductase 2 147 2.4E-25 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS06860 3b01522dbfb9d940b31f851fe04b9e08 191 Gene3D G3DSA:3.40.50.360 1 190 2.3E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS08095 77909eb33756567e95d5d85561f58aff 123 SUPERFAMILY SSF53146 1 122 3.4E-35 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CWR56_RS08095 77909eb33756567e95d5d85561f58aff 123 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 101 2.9E-17 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CWR56_RS08095 77909eb33756567e95d5d85561f58aff 123 Gene3D G3DSA:3.30.420.130 1 123 2.3E-26 T 29-03-2018 CWR56_RS08445 16da7df35ca8b13c807e05a507d47753 153 Gene3D G3DSA:1.10.440.10 2 112 2.2E-4 T 29-03-2018 IPR024796 T4 endonuclease V CWR56_RS08445 16da7df35ca8b13c807e05a507d47753 153 Pfam PF03013 Pyrimidine dimer DNA glycosylase 1 115 2.4E-26 T 29-03-2018 IPR004260 Pyrimidine dimer DNA glycosylase CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 304 317 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 SUPERFAMILY SSF55785 152 204 7.95E-5 T 29-03-2018 IPR000014 PAS domain CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 Gene3D G3DSA:1.10.10.60 547 585 1.1E-13 T 29-03-2018 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 Gene3D G3DSA:1.10.8.60 454 546 2.9E-21 T 29-03-2018 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 SMART SM00382 300 444 5.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 494 503 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 Pfam PF02954 Bacterial regulatory protein, Fis family 544 587 1.1E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 367 382 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 SUPERFAMILY SSF52540 279 524 1.04E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 Gene3D G3DSA:3.30.450.20 144 287 1.3E-6 T 29-03-2018 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 Pfam PF00158 Sigma-54 interaction domain 280 448 5.8E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 SUPERFAMILY SSF46689 494 589 1.49E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16250 c8dc78b76eb33b6ba5506ef7bdbb6fd6 591 Gene3D G3DSA:3.40.50.300 288 453 2.3E-25 T 29-03-2018 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 305 5.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 SMART SM00387 359 467 6.4E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 3.6E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 Gene3D G3DSA:1.10.287.130 229 307 5.4E-11 T 29-03-2018 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 466 8.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 SMART SM00388 245 313 3.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 SUPERFAMILY SSF55874 302 467 1.83E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 SUPERFAMILY SSF47384 241 312 7.06E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09280 fab67a9cfb42750e5fa22e06c9edb72a 467 Gene3D G3DSA:3.30.565.10 340 467 4.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03625 335fe8a575072af21ce5725d0ba01e1d 486 SUPERFAMILY SSF53850 36 386 1.63E-28 T 29-03-2018 CWR56_RS03625 335fe8a575072af21ce5725d0ba01e1d 486 Pfam PF13416 Bacterial extracellular solute-binding protein 56 386 2.2E-28 T 29-03-2018 CWR56_RS03625 335fe8a575072af21ce5725d0ba01e1d 486 Gene3D G3DSA:3.40.190.10 158 486 1.5E-17 T 29-03-2018 CWR56_RS03540 af9348357380e5fc2b8f0948bf8b5569 290 SMART SM00729 32 226 2.2E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS03540 af9348357380e5fc2b8f0948bf8b5569 290 SUPERFAMILY SSF102114 9 264 1.31E-24 T 29-03-2018 CWR56_RS03540 af9348357380e5fc2b8f0948bf8b5569 290 Gene3D G3DSA:3.20.20.70 1 286 7.7E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 213 5.7E-53 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 Pfam PF01895 PhoU domain 20 104 4.4E-20 T 29-03-2018 IPR026022 PhoU domain CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 Pfam PF01895 PhoU domain 121 204 1.2E-17 T 29-03-2018 IPR026022 PhoU domain CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 PIRSF PIRSF003107 1 217 2.3E-61 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 SUPERFAMILY SSF109755 4 215 1.05E-57 T 29-03-2018 CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 Gene3D G3DSA:1.20.58.220 1 110 2.0E-25 T 29-03-2018 CWR56_RS16395 f7b317de16b17882c8d2b22eb838a91d 217 Gene3D G3DSA:1.20.58.220 111 217 1.5E-22 T 29-03-2018 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 SMART SM01018 586 668 6.7E-17 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 SUPERFAMILY SSF52242 669 790 8.5E-42 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Pfam PF02574 Homocysteine S-methyltransferase 12 286 8.6E-62 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Pfam PF02607 B12 binding domain 598 658 6.2E-10 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Gene3D G3DSA:3.20.20.20 307 574 1.7E-52 T 29-03-2018 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Gene3D G3DSA:3.20.20.330 1 299 8.6E-80 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 SUPERFAMILY SSF82282 3 357 7.06E-105 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 SUPERFAMILY SSF47644 602 664 9.15E-10 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Gene3D G3DSA:3.40.50.280 661 791 4.5E-41 T 29-03-2018 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Pfam PF00809 Pterin binding enzyme 319 541 4.9E-31 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 PIRSF PIRSF037472 1 792 0.0 T 29-03-2018 IPR017215 5-methyltetrahydrofolate-homocysteine S-methyltransferase, bacterial CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Pfam PF02310 B12 binding domain 676 777 1.5E-24 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 SUPERFAMILY SSF51717 316 573 7.33E-83 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17960 d29a9a436392028d7d40f1071b6a579f 793 Gene3D G3DSA:1.10.1240.10 584 660 2.0E-13 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 424 1.9E-46 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 Gene3D G3DSA:3.90.1820.10 1 284 4.8E-59 T 29-03-2018 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 Gene3D G3DSA:3.90.1820.10 285 450 6.0E-43 T 29-03-2018 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 137 154 1.2E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 72 88 1.2E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 93 106 1.2E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 163 174 1.2E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.2E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 1.2E-34 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 SUPERFAMILY SSF56327 167 449 3.89E-78 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 SUPERFAMILY SSF51735 3 168 2.19E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS12675 6667189af95f9194e1980f9feb11560a 450 Pfam PF02056 Family 4 glycosyl hydrolase 3 183 1.8E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS03230 51154e0e3a874893f7683c27a0bce22b 233 Pfam PF16481 Domain of unknown function (DUF5058) 8 225 1.6E-61 T 29-03-2018 IPR032479 Protein of unknown function DUF5058 CWR56_RS09260 7ec85c74de2e9ac84afccdd8f1509683 153 Pfam PF12681 Glyoxalase-like domain 3 120 1.8E-52 T 29-03-2018 IPR025870 Glyoxalase-like domain CWR56_RS09260 7ec85c74de2e9ac84afccdd8f1509683 153 Gene3D G3DSA:3.10.180.10 6 131 1.5E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS09260 7ec85c74de2e9ac84afccdd8f1509683 153 SUPERFAMILY SSF54593 1 116 1.41E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS17165 46dd04c03f17e0f5e88e918de79f1026 440 PIRSF PIRSF006351 2 429 3.5E-105 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS17165 46dd04c03f17e0f5e88e918de79f1026 440 Pfam PF02378 Phosphotransferase system, EIIC 31 345 2.8E-39 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS17165 46dd04c03f17e0f5e88e918de79f1026 440 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 416 1.1E-77 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 Gene3D G3DSA:3.30.1490.20 159 227 3.9E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 Gene3D G3DSA:3.30.470.20 228 366 8.0E-38 T 29-03-2018 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 Gene3D G3DSA:3.40.50.20 1 158 9.1E-41 T 29-03-2018 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 Pfam PF07478 D-ala D-ala ligase C-terminus 164 362 2.4E-64 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 362 8.6E-97 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 PIRSF PIRSF039102 1 366 1.6E-111 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 SUPERFAMILY SSF56059 157 362 2.05E-51 T 29-03-2018 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 365 36.96 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 SUPERFAMILY SSF52440 4 156 2.3E-34 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 Pfam PF01820 D-ala D-ala ligase N-terminus 5 147 3.6E-31 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 124 135 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS07730 040e172facf9a56594d2bea4badc6b45 366 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 307 335 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 366 33.712 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 362 1.2E-91 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 Gene3D G3DSA:3.40.50.2000 181 350 3.7E-28 T 29-03-2018 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 SUPERFAMILY SSF53756 2 367 6.48E-106 T 29-03-2018 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 193 356 1.3E-32 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 Gene3D G3DSA:3.40.50.2000 1 180 3.8E-35 T 29-03-2018 CWR56_RS13415 0e02fc226f762b55291cb155a4e69c22 409 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 143 2.9E-44 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS08705 3603a98f6fd263359a9a0acfd5c1c503 323 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 34 58 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR56_RS08705 3603a98f6fd263359a9a0acfd5c1c503 323 Gene3D G3DSA:3.40.1190.20 2 323 3.9E-65 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS08705 3603a98f6fd263359a9a0acfd5c1c503 323 SUPERFAMILY SSF53613 1 320 2.65E-78 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS08705 3603a98f6fd263359a9a0acfd5c1c503 323 Pfam PF00294 pfkB family carbohydrate kinase 1 310 3.8E-72 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CWR56_RS02135 a69f25d73b9fe903ca2dcfcd18913b52 249 SUPERFAMILY SSF46689 1 73 5.02E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02135 a69f25d73b9fe903ca2dcfcd18913b52 249 Gene3D G3DSA:1.10.10.10 1 106 6.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02135 a69f25d73b9fe903ca2dcfcd18913b52 249 Gene3D G3DSA:3.40.50.10490 107 237 6.0E-12 T 29-03-2018 CWR56_RS02135 a69f25d73b9fe903ca2dcfcd18913b52 249 Pfam PF01380 SIS domain 110 226 1.4E-14 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS02135 a69f25d73b9fe903ca2dcfcd18913b52 249 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 72 2.2E-16 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS02135 a69f25d73b9fe903ca2dcfcd18913b52 249 SUPERFAMILY SSF53697 91 238 2.11E-17 T 29-03-2018 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 Gene3D G3DSA:3.90.226.10 42 311 2.1E-60 T 29-03-2018 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 2 313 44.954 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 SUPERFAMILY SSF52096 15 312 1.26E-90 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 3.9E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 3.9E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 3.9E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 3.9E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 3.9E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 3.9E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 7 313 5.1E-132 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09210 3f3d65c0b29c6f66166ee55afa8c3692 314 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 145 3.5E-56 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 494 5.1E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Gene3D G3DSA:2.30.38.10 308 399 1.8E-22 T 29-03-2018 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 504 202.54 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 SUPERFAMILY SSF56801 12 502 5.49E-108 T 29-03-2018 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Gene3D G3DSA:3.40.50.980 152 307 1.4E-31 T 29-03-2018 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Gene3D G3DSA:3.40.50.980 8 151 9.1E-23 T 29-03-2018 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 26 431 3.3E-101 T 29-03-2018 IPR010071 Amino acid adenylation domain CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Gene3D G3DSA:3.30.300.30 400 504 1.4E-20 T 29-03-2018 CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 146 157 - T 29-03-2018 IPR020845 AMP-binding, conserved site CWR56_RS14500 f68ee6e2c2734d47d26c81f5abf92586 504 Pfam PF00501 AMP-binding enzyme 12 406 1.8E-77 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 SUPERFAMILY SSF50692 606 723 2.71E-26 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Gene3D G3DSA:2.40.40.20 602 725 7.9E-23 T 29-03-2018 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Gene3D G3DSA:3.40.50.740 97 195 3.2E-20 T 29-03-2018 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 SMART SM00926 36 92 1.2E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Pfam PF00384 Molybdopterin oxidoreductase 95 515 4.9E-63 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 SUPERFAMILY SSF53706 38 606 1.28E-138 T 29-03-2018 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Pfam PF01568 Molydopterin dinucleotide binding domain 618 716 8.2E-16 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Gene3D G3DSA:2.20.25.90 29 96 2.0E-17 T 29-03-2018 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 461 478 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 91 1.0E-12 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Gene3D G3DSA:3.40.228.10 196 362 2.8E-44 T 29-03-2018 CWR56_RS10515 5930bdaf0f40ef1236dcac95a69bf447 725 Gene3D G3DSA:3.40.228.10 407 591 5.4E-6 T 29-03-2018 CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 Gene3D G3DSA:2.40.30.10 206 299 1.6E-24 T 29-03-2018 CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 SUPERFAMILY SSF160996 207 363 6.41E-38 T 29-03-2018 CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 Pfam PF03486 HI0933-like protein 3 414 2.6E-127 T 29-03-2018 CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 Gene3D G3DSA:3.50.50.60 1 191 3.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 414 2.5E-128 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 SUPERFAMILY SSF51905 3 208 9.61E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08755 5a4f55b81368699a44609aa4acad0f40 417 SUPERFAMILY SSF51905 360 417 9.61E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 Pfam PF08264 Anticodon-binding domain of tRNA 679 826 1.0E-32 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 SUPERFAMILY SSF47323 649 880 4.11E-52 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 623 7.0E-184 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 Gene3D G3DSA:3.40.50.620 378 620 7.6E-90 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 Gene3D G3DSA:3.90.740.10 190 377 9.3E-60 T 29-03-2018 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 SUPERFAMILY SSF52374 386 639 1.64E-135 T 29-03-2018 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 SUPERFAMILY SSF52374 13 199 1.64E-135 T 29-03-2018 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 11 834 9.8E-294 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 SUPERFAMILY SSF50677 207 379 2.72E-45 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1034 13.687 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 Gene3D G3DSA:1.10.730.10 621 791 1.8E-41 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 511 524 2.1E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 2.1E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 2.1E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 551 560 2.1E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR56_RS13230 b6f5985a68bfd0f1bd0fa7cfc104c97a 1035 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 221 244 2.1E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR56_RS05220 acb6368321a3bd0d8c59f5c8f15bb63e 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 261 3.9E-123 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CWR56_RS05220 acb6368321a3bd0d8c59f5c8f15bb63e 265 Gene3D G3DSA:3.40.50.300 1 241 2.3E-53 T 29-03-2018 CWR56_RS05220 acb6368321a3bd0d8c59f5c8f15bb63e 265 PIRSF PIRSF003092 1 265 2.3E-91 T 29-03-2018 IPR025501 ATP binding protein MinD CWR56_RS05220 acb6368321a3bd0d8c59f5c8f15bb63e 265 SUPERFAMILY SSF52540 1 247 7.13E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05220 acb6368321a3bd0d8c59f5c8f15bb63e 265 Pfam PF13614 AAA domain 3 160 1.5E-23 T 29-03-2018 IPR025669 AAA domain CWR56_RS12260 201c73836e9eb72f352494c51e34dea6 358 SUPERFAMILY SSF52518 2 248 3.02E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS12260 201c73836e9eb72f352494c51e34dea6 358 Gene3D G3DSA:3.40.50.970 1 273 8.3E-50 T 29-03-2018 CWR56_RS12260 201c73836e9eb72f352494c51e34dea6 358 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 241 1.1E-46 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CWR56_RS12260 201c73836e9eb72f352494c51e34dea6 358 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 246 325 1.6E-19 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CWR56_RS12260 201c73836e9eb72f352494c51e34dea6 358 SUPERFAMILY SSF52922 237 322 9.28E-20 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 Pfam PF00122 E1-E2 ATPase 106 282 2.8E-34 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 74 343 7.8E-34 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 368 599 5.1E-46 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 306 312 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 Gene3D G3DSA:3.40.50.1000 442 571 5.8E-35 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 550 5.8E-24 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 153 167 5.8E-24 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 5.8E-24 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 462 472 5.8E-24 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 534 5.8E-24 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF81665 207 298 4.58E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF81665 572 656 4.58E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF81665 30 105 4.58E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 679 40.373 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 Gene3D G3DSA:2.70.150.10 5 207 1.7E-25 T 29-03-2018 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF56784 434 559 4.65E-38 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF56784 351 403 4.65E-38 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF56784 292 316 4.65E-38 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 3 676 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 Gene3D G3DSA:3.40.1110.10 315 441 2.5E-18 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 SUPERFAMILY SSF81653 115 206 1.83E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS07555 f3d409c742086e735f1edb97da34bfb1 685 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 529 2.7E-31 T 29-03-2018 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 83 168 5.3E-32 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 169 27.034 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 76 8.7E-33 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 169 2.1E-61 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 Gene3D G3DSA:3.30.110.10 79 169 1.5E-30 T 29-03-2018 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 SUPERFAMILY SSF55200 84 169 5.36E-28 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 SUPERFAMILY SSF54364 6 78 7.19E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CWR56_RS03280 fd8d02aaa878508efac20a7634b658bc 169 Gene3D G3DSA:3.10.20.80 2 78 1.7E-34 T 29-03-2018 CWR56_RS17125 f62b323a509666faf0f91984a4a18910 257 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 3 247 1.9E-44 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17125 f62b323a509666faf0f91984a4a18910 257 Pfam PF02654 Cobalamin-5-phosphate synthase 8 246 2.2E-53 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17125 f62b323a509666faf0f91984a4a18910 257 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 257 39.345 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17865 a207a2f5e424707946652e37ec4331e4 384 Gene3D G3DSA:3.40.640.10 7 259 9.9E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS17865 a207a2f5e424707946652e37ec4331e4 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 381 7.4E-115 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR56_RS17865 a207a2f5e424707946652e37ec4331e4 384 PIRSF PIRSF001434 1 384 2.2E-118 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR56_RS17865 a207a2f5e424707946652e37ec4331e4 384 SUPERFAMILY SSF53383 6 383 1.22E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS17865 a207a2f5e424707946652e37ec4331e4 384 Gene3D G3DSA:3.90.1150.10 261 384 1.2E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS17865 a207a2f5e424707946652e37ec4331e4 384 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR56_RS03180 0e5c2f2e90a8c35e7c00bdc40b452efa 304 SMART SM00382 29 213 2.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03180 0e5c2f2e90a8c35e7c00bdc40b452efa 304 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS03180 0e5c2f2e90a8c35e7c00bdc40b452efa 304 Pfam PF00005 ABC transporter 21 161 3.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS03180 0e5c2f2e90a8c35e7c00bdc40b452efa 304 SUPERFAMILY SSF52540 3 223 2.82E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03180 0e5c2f2e90a8c35e7c00bdc40b452efa 304 Gene3D G3DSA:3.40.50.300 1 249 4.1E-57 T 29-03-2018 CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 SMART SM00382 26 229 5.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 Pfam PF00005 ABC transporter 17 165 6.1E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 SUPERFAMILY SSF55021 234 318 1.83E-15 T 29-03-2018 CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 Pfam PF09383 NIL domain 247 317 1.3E-15 T 29-03-2018 IPR018449 NIL domain CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 SUPERFAMILY SSF52540 1 229 7.1E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 Gene3D G3DSA:3.40.50.300 1 238 3.1E-76 T 29-03-2018 CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 Gene3D G3DSA:3.30.70.260 239 320 1.7E-13 T 29-03-2018 CWR56_RS07015 cffe6aa1a84d5540be579e7e954184b7 321 SMART SM00930 245 318 5.8E-18 T 29-03-2018 IPR018449 NIL domain CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Pfam PF01751 Toprim domain 4 114 3.5E-32 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 614 653 4.1E-15 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 656 683 1.4 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 575 611 1.1E-15 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Pfam PF01131 DNA topoisomerase 129 546 4.5E-131 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 SMART SM00436 105 193 3.8E-51 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 SUPERFAMILY SSF56712 3 587 2.88E-193 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 472 486 7.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 374 390 7.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 78 91 7.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 163 181 7.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 295 304 7.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 SMART SM00437 244 509 2.7E-110 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:3.40.50.140 2 130 6.8E-41 T 29-03-2018 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 SMART SM00493 3 104 1.1E-33 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 281 304 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 SUPERFAMILY SSF57783 572 610 5.67E-13 T 29-03-2018 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:3.30.65.10 612 651 2.2E-11 T 29-03-2018 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:3.30.65.10 564 611 8.8E-17 T 29-03-2018 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:3.30.65.10 652 694 5.2E-4 T 29-03-2018 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:2.70.20.10 329 449 8.1E-39 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 631 54.238 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 609 1.5E-243 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:1.10.460.10 136 328 8.8E-45 T 29-03-2018 CWR56_RS05900 ba526c0bc679340b3f2af55b238d98b2 695 Gene3D G3DSA:1.10.460.10 450 563 8.9E-28 T 29-03-2018 CWR56_RS12085 1c003859260dd26b25c4b7c098df1f65 168 Gene3D G3DSA:3.30.420.10 1 142 4.9E-39 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS12085 1c003859260dd26b25c4b7c098df1f65 168 SUPERFAMILY SSF53098 1 167 9.19E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS12085 1c003859260dd26b25c4b7c098df1f65 168 Gene3D G3DSA:1.20.5.140 146 167 6.8E-5 T 29-03-2018 CWR56_RS12085 1c003859260dd26b25c4b7c098df1f65 168 SMART SM00479 3 168 1.4E-41 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS12085 1c003859260dd26b25c4b7c098df1f65 168 Pfam PF00929 Exonuclease 5 161 2.7E-35 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS12085 1c003859260dd26b25c4b7c098df1f65 168 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 162 1.6E-27 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS14095 a0c0307a5e852f17a1ad9d053956b0ad 357 Gene3D G3DSA:3.90.550.10 2 352 2.2E-88 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14095 a0c0307a5e852f17a1ad9d053956b0ad 357 SUPERFAMILY SSF159283 285 349 8.63E-21 T 29-03-2018 CWR56_RS14095 a0c0307a5e852f17a1ad9d053956b0ad 357 Pfam PF01050 Mannose-6-phosphate isomerase 316 356 1.1E-9 T 29-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CWR56_RS14095 a0c0307a5e852f17a1ad9d053956b0ad 357 SUPERFAMILY SSF53448 1 279 4.13E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14095 a0c0307a5e852f17a1ad9d053956b0ad 357 Pfam PF00483 Nucleotidyl transferase 5 282 1.2E-46 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 SUPERFAMILY SSF56322 18 446 8.24E-143 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 Gene3D G3DSA:3.60.120.10 7 452 7.0E-158 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 Pfam PF00425 chorismate binding enzyme 185 438 5.6E-100 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 88 441 2.3E-118 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 Pfam PF04715 Anthranilate synthase component I, N terminal region 14 135 2.6E-30 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 PRINTS PR00095 Anthranilate synthase component I signature 300 313 2.5E-18 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 PRINTS PR00095 Anthranilate synthase component I signature 395 409 2.5E-18 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 PRINTS PR00095 Anthranilate synthase component I signature 380 394 2.5E-18 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR56_RS06800 49e5d390a12ce704aa9a11f94e1e231a 452 PRINTS PR00095 Anthranilate synthase component I signature 286 299 2.5E-18 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 SUPERFAMILY SSF56784 1 269 6.72E-68 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 219 241 - T 29-03-2018 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 238 1.9E-29 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 265 1.9E-59 T 29-03-2018 IPR000150 Cof family GO:0016787 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 242 254 1.9E-5 T 29-03-2018 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 7 21 1.9E-5 T 29-03-2018 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 219 238 1.9E-5 T 29-03-2018 CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 265 1.2E-63 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS15505 b165100b651caf2162d1f8481fcd7e9a 270 Gene3D G3DSA:3.40.50.1000 1 270 7.5E-43 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS16810 850456b9d74113ed374a3d88c8568185 194 SUPERFAMILY SSF52317 1 190 9.8E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS16810 850456b9d74113ed374a3d88c8568185 194 Pfam PF01965 DJ-1/PfpI family 1 175 9.6E-32 T 29-03-2018 IPR002818 DJ-1/PfpI CWR56_RS16810 850456b9d74113ed374a3d88c8568185 194 Gene3D G3DSA:3.40.50.880 1 194 3.7E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 6.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 6.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 SMART SM00871 129 282 1.2E-29 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 Pfam PF06445 GyrI-like small molecule binding domain 129 281 1.2E-22 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 SUPERFAMILY SSF55136 129 284 7.59E-24 T 29-03-2018 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 SMART SM00342 21 104 2.3E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 SUPERFAMILY SSF46689 4 55 3.27E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 Gene3D G3DSA:3.20.80.10 129 282 6.8E-40 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 Gene3D G3DSA:3.90.1240.10 2 128 3.0E-25 T 29-03-2018 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 SUPERFAMILY SSF46689 57 107 1.3E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08920 8b2c4d4d61b84cd5075d6a59aa950cff 284 Pfam PF12833 Helix-turn-helix domain 28 106 3.0E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS07365 52142a790e485c8852255d9d957f70f7 252 Pfam PF00977 Histidine biosynthesis protein 5 234 2.1E-82 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CWR56_RS07365 52142a790e485c8852255d9d957f70f7 252 SUPERFAMILY SSF51366 1 251 3.14E-76 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS07365 52142a790e485c8852255d9d957f70f7 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 45.325 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CWR56_RS07365 52142a790e485c8852255d9d957f70f7 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 3.7E-107 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CWR56_RS07365 52142a790e485c8852255d9d957f70f7 252 Gene3D G3DSA:3.20.20.70 4 247 2.5E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13085 9f2b03e72bf9f6a02b9bbcc919f4d3c1 88 SUPERFAMILY SSF63562 1 82 7.46E-24 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR56_RS13085 9f2b03e72bf9f6a02b9bbcc919f4d3c1 88 SMART SM01409 8 61 1.1E-10 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR56_RS13085 9f2b03e72bf9f6a02b9bbcc919f4d3c1 88 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 15.352 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS13085 9f2b03e72bf9f6a02b9bbcc919f4d3c1 88 Gene3D G3DSA:3.90.940.10 1 88 4.2E-23 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR56_RS13085 9f2b03e72bf9f6a02b9bbcc919f4d3c1 88 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.9E-13 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS13085 9f2b03e72bf9f6a02b9bbcc919f4d3c1 88 Pfam PF01192 RNA polymerase Rpb6 9 61 1.5E-12 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 SUPERFAMILY SSF53187 374 435 1.66E-52 T 29-03-2018 CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 SUPERFAMILY SSF53187 298 327 1.66E-52 T 29-03-2018 CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 SUPERFAMILY SSF53187 7 199 1.66E-52 T 29-03-2018 CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 PIRSF PIRSF037227 2 461 1.5E-162 T 29-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 Gene3D G3DSA:3.40.630.10 4 455 3.1E-47 T 29-03-2018 CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 Pfam PF07687 Peptidase dimerisation domain 188 278 6.1E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 SUPERFAMILY SSF55031 187 294 2.62E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS01570 e7415e885bf2cad001250fab2df62826 461 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 397 9.0E-70 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS10595 8dd842bb7691112f4568acaf15ef314b 171 SUPERFAMILY SSF47240 1 158 1.1E-53 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS10595 8dd842bb7691112f4568acaf15ef314b 171 Pfam PF00210 Ferritin-like domain 8 142 9.5E-40 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CWR56_RS10595 8dd842bb7691112f4568acaf15ef314b 171 Gene3D G3DSA:1.20.1260.10 1 160 6.9E-42 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS17160 cafe8f3a4331719d373e3086035e867d 356 Pfam PF00557 Metallopeptidase family M24 136 336 1.1E-63 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS17160 cafe8f3a4331719d373e3086035e867d 356 SUPERFAMILY SSF53092 10 128 2.09E-11 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS17160 cafe8f3a4331719d373e3086035e867d 356 SUPERFAMILY SSF55920 127 354 5.76E-73 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS17160 cafe8f3a4331719d373e3086035e867d 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 128 3.9E-11 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR56_RS17160 cafe8f3a4331719d373e3086035e867d 356 Gene3D G3DSA:3.40.350.10 1 126 1.7E-15 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS17160 cafe8f3a4331719d373e3086035e867d 356 Gene3D G3DSA:3.90.230.10 127 354 7.0E-72 T 29-03-2018 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 Pfam PF13174 Tetratricopeptide repeat 421 453 0.0016 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 SUPERFAMILY SSF48452 14 165 2.23E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 SUPERFAMILY SSF48452 345 455 9.48E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 Gene3D G3DSA:1.25.40.10 122 323 0.015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 Gene3D G3DSA:1.20.120.420 12 121 7.4E-4 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 Gene3D G3DSA:1.25.40.10 393 466 4.7E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 SMART SM00028 420 453 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 SMART SM00028 345 378 160.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 SMART SM00028 56 89 100.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 SMART SM00028 382 415 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01395 e0030df74249db068ec7ca86afa3cae2 467 Gene3D G3DSA:1.10.150.160 344 392 0.014 T 29-03-2018 CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 SMART SM00448 7 116 5.4E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 Gene3D G3DSA:3.40.50.2300 1 132 9.9E-35 T 29-03-2018 CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 Pfam PF00072 Response regulator receiver domain 9 116 6.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 1.4E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 SMART SM00862 156 233 2.2E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 SUPERFAMILY SSF52172 7 190 3.56E-38 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS13800 ebb1bb0af2aaeee86a36e1ed08a829e3 234 Gene3D G3DSA:1.10.10.10 133 234 2.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12015 16dd95d7f0fc9430341130e25c3b3d69 419 Pfam PF00155 Aminotransferase class I and II 37 402 4.4E-34 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS12015 16dd95d7f0fc9430341130e25c3b3d69 419 Gene3D G3DSA:3.90.1150.10 302 415 1.1E-6 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS12015 16dd95d7f0fc9430341130e25c3b3d69 419 SUPERFAMILY SSF53383 20 397 5.41E-58 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12015 16dd95d7f0fc9430341130e25c3b3d69 419 Gene3D G3DSA:3.90.1150.10 1 84 2.2E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS12015 16dd95d7f0fc9430341130e25c3b3d69 419 Gene3D G3DSA:3.40.640.10 85 301 2.5E-32 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS05890 29a169a51c0757737e197771c059f933 533 SUPERFAMILY SSF54211 10 168 1.48E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS05890 29a169a51c0757737e197771c059f933 533 Pfam PF01078 Magnesium chelatase, subunit ChlI 217 421 5.4E-89 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain CWR56_RS05890 29a169a51c0757737e197771c059f933 533 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 525 9.8E-173 T 29-03-2018 IPR004482 Mg chelatase-related protein CWR56_RS05890 29a169a51c0757737e197771c059f933 533 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 430 525 8.8E-25 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CWR56_RS05890 29a169a51c0757737e197771c059f933 533 SUPERFAMILY SSF52540 216 525 4.83E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05890 29a169a51c0757737e197771c059f933 533 Gene3D G3DSA:3.30.230.10 3 185 1.1E-39 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS05890 29a169a51c0757737e197771c059f933 533 SMART SM00382 237 419 8.5E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05890 29a169a51c0757737e197771c059f933 533 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 142 3.6E-46 T 29-03-2018 CWR56_RS05890 29a169a51c0757737e197771c059f933 533 Gene3D G3DSA:3.40.50.300 186 455 2.3E-25 T 29-03-2018 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 SUPERFAMILY SSF111342 130 321 4.97E-78 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 SUPERFAMILY SSF111342 3 90 4.97E-78 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 Gene3D G3DSA:3.30.2110.10 14 218 9.4E-58 T 29-03-2018 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 PIRSF PIRSF026782 8 404 1.5E-118 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 125 395 1.6E-78 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 Pfam PF01888 CbiD 13 303 1.3E-91 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS17085 8523a5e37705b66fb26d1f9a1f7f1fca 408 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 12 397 29.255 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SMART SM00479 10 172 1.5E-4 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 Pfam PF13307 Helicase C-terminal domain 781 918 2.9E-17 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SUPERFAMILY SSF53098 10 272 3.44E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SMART SM00487 262 525 0.0025 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SMART SM00491 806 931 1.3E-5 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 Gene3D G3DSA:3.30.420.10 10 184 4.3E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 Gene3D G3DSA:3.40.50.300 263 746 1.8E-20 T 29-03-2018 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 Gene3D G3DSA:3.40.50.300 764 1023 1.1E-4 T 29-03-2018 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 Pfam PF04851 Type III restriction enzyme, res subunit 264 498 5.6E-5 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SUPERFAMILY SSF52540 190 364 1.16E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SUPERFAMILY SSF52540 882 917 1.16E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06725 6954242117e72841d4f3fd2dbb63a046 1039 SUPERFAMILY SSF52540 445 496 1.16E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 451 7.4E-22 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 SUPERFAMILY SSF53738 29 236 1.37E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Gene3D G3DSA:3.30.310.50 455 565 3.2E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Gene3D G3DSA:3.40.120.10 17 214 2.5E-55 T 29-03-2018 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Gene3D G3DSA:3.40.120.10 215 336 2.2E-28 T 29-03-2018 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 1.2E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 140 154 1.2E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 SUPERFAMILY SSF53738 227 314 1.33E-18 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 SUPERFAMILY SSF55957 468 557 2.88E-16 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 183 2.0E-41 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 SUPERFAMILY SSF53738 304 454 5.49E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 498 539 8.3E-9 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 208 312 2.0E-24 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 Gene3D G3DSA:3.40.120.10 337 454 2.4E-35 T 29-03-2018 CWR56_RS07470 40317a952cf8f19d44109cb0eb3226db 565 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 SUPERFAMILY SSF47384 178 258 1.49E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 SMART SM00387 304 414 2.3E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 Gene3D G3DSA:3.30.565.10 241 410 1.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 197 258 8.7E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 SMART SM00388 194 259 8.1E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 Gene3D G3DSA:1.10.287.130 162 240 6.6E-9 T 29-03-2018 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 410 3.4E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 355 2.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 369 2.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 2.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 2.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06895 fabde28d7b4629cd7b800672ab4db61d 417 SUPERFAMILY SSF55874 249 410 2.49E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 Pfam PF00072 Response regulator receiver domain 4 119 4.8E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 SMART SM00850 140 230 2.3E-21 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 Gene3D G3DSA:3.40.50.2300 2 133 3.5E-22 T 29-03-2018 CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 Pfam PF04397 LytTr DNA-binding domain 142 226 2.3E-19 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 SUPERFAMILY SSF52172 3 136 8.54E-22 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 Gene3D G3DSA:2.40.50.40 134 199 3.7E-19 T 29-03-2018 CWR56_RS02870 05592033f6505752acde6c7afc03afe6 236 SMART SM00448 2 119 8.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS03930 caacc1e24bf2600ddd9fe56a985236d8 264 Gene3D G3DSA:3.40.50.620 1 263 3.1E-80 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS03930 caacc1e24bf2600ddd9fe56a985236d8 264 Pfam PF01012 Electron transfer flavoprotein domain 22 210 5.8E-49 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS03930 caacc1e24bf2600ddd9fe56a985236d8 264 PIRSF PIRSF000090 1 264 2.1E-91 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CWR56_RS03930 caacc1e24bf2600ddd9fe56a985236d8 264 SMART SM00893 22 215 2.7E-64 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS03930 caacc1e24bf2600ddd9fe56a985236d8 264 SUPERFAMILY SSF52402 1 258 1.26E-81 T 29-03-2018 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Gene3D G3DSA:2.40.50.100 115 176 2.7E-24 T 29-03-2018 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 SUPERFAMILY SSF47917 448 554 7.59E-26 T 29-03-2018 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 SMART SM00382 224 412 0.0089 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 1.6E-13 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Gene3D G3DSA:1.10.1140.10 446 558 1.0E-30 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Gene3D G3DSA:3.40.50.300 177 435 6.0E-100 T 29-03-2018 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 426 435 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 SUPERFAMILY SSF52540 168 439 5.97E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 50.911 T 29-03-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 SUPERFAMILY SSF50615 2 70 2.59E-12 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 212 435 5.5E-92 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14700 00c6a3443cc8344bcdeb1f72fde03c46 592 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 202 5.4E-44 T 29-03-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 SUPERFAMILY SSF54171 5 74 1.31E-30 T 29-03-2018 IPR016177 DNA-binding domain GO:0003677 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 Pfam PF02920 DNA binding domain of tn916 integrase 4 72 3.7E-27 T 29-03-2018 IPR004191 Integrase, Tn916-type, N-terminal DNA binding GO:0003677|GO:0008907|GO:0015074 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 Pfam PF00589 Phage integrase family 192 383 4.3E-38 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 Gene3D G3DSA:3.30.160.60 6 71 4.9E-25 T 29-03-2018 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 SUPERFAMILY SSF56349 94 386 2.33E-46 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 Gene3D G3DSA:1.10.443.10 187 395 4.2E-35 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 Gene3D G3DSA:1.10.150.130 78 186 2.2E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS11830 2f4fa512ff41ad61ddee7bfcf9cd9b6b 396 Pfam PF13102 Phage integrase SAM-like domain 91 175 3.9E-5 T 29-03-2018 IPR025269 Phage integrase SAM-like domain CWR56_RS12425 57be02652d1352adc3c32491a859a7c4 311 Gene3D G3DSA:3.30.420.40 1 119 1.5E-21 T 29-03-2018 CWR56_RS12425 57be02652d1352adc3c32491a859a7c4 311 Gene3D G3DSA:3.30.420.40 120 311 1.1E-49 T 29-03-2018 CWR56_RS12425 57be02652d1352adc3c32491a859a7c4 311 SUPERFAMILY SSF53067 1 311 7.35E-60 T 29-03-2018 CWR56_RS12425 57be02652d1352adc3c32491a859a7c4 311 Pfam PF00480 ROK family 3 311 5.6E-64 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS15065 bcf74cf7d5c8d8d2fb36c6d63d38dcc4 478 Gene3D G3DSA:2.160.20.10 11 231 4.6E-12 T 29-03-2018 IPR012334 Pectin lyase fold CWR56_RS15065 bcf74cf7d5c8d8d2fb36c6d63d38dcc4 478 Gene3D G3DSA:2.160.20.70 232 283 0.023 T 29-03-2018 CWR56_RS15065 bcf74cf7d5c8d8d2fb36c6d63d38dcc4 478 SUPERFAMILY SSF51126 10 319 3.84E-11 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CWR56_RS15065 bcf74cf7d5c8d8d2fb36c6d63d38dcc4 478 Pfam PF12708 Pectate lyase superfamily protein 12 215 7.5E-31 T 29-03-2018 IPR024535 Pectate lyase superfamily protein CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Gene3D G3DSA:3.40.930.10 824 966 1.5E-23 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Gene3D G3DSA:1.10.1790.10 464 582 3.0E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 SUPERFAMILY SSF55804 827 962 5.36E-24 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 SMART SM00382 142 292 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Pfam PF00874 PRD domain 503 586 2.6E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Pfam PF00158 Sigma-54 interaction domain 119 284 1.1E-45 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Gene3D G3DSA:3.40.50.300 87 330 5.0E-22 T 29-03-2018 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Pfam PF03610 PTS system fructose IIA component 597 696 1.4E-9 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 SUPERFAMILY SSF52540 119 359 5.33E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 SUPERFAMILY SSF63520 477 589 4.58E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 SUPERFAMILY SSF53062 596 702 7.19E-16 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 829 961 4.5E-26 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11310 3960a01f995ac4015afeb71a47b0e5e4 967 Gene3D G3DSA:3.40.50.510 583 728 3.5E-24 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS10205 51f3f500d3c2449a36373258bbbc6bdd 311 Gene3D G3DSA:1.20.58.340 132 243 1.3E-12 T 29-03-2018 CWR56_RS10205 51f3f500d3c2449a36373258bbbc6bdd 311 SUPERFAMILY SSF143865 4 245 5.62E-51 T 29-03-2018 CWR56_RS10205 51f3f500d3c2449a36373258bbbc6bdd 311 Gene3D G3DSA:1.20.58.340 244 311 6.5E-19 T 29-03-2018 CWR56_RS10205 51f3f500d3c2449a36373258bbbc6bdd 311 SUPERFAMILY SSF144083 246 308 2.75E-17 T 29-03-2018 CWR56_RS10205 51f3f500d3c2449a36373258bbbc6bdd 311 Pfam PF01544 CorA-like Mg2+ transporter protein 21 306 1.3E-65 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR56_RS10205 51f3f500d3c2449a36373258bbbc6bdd 311 Gene3D G3DSA:3.30.460.20 3 131 1.6E-22 T 29-03-2018 CWR56_RS08145 29947d62931733f447beb471dacd4b4b 64 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 1 64 1.7E-20 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis CWR56_RS08145 29947d62931733f447beb471dacd4b4b 64 Gene3D G3DSA:3.10.20.30 1 64 1.6E-17 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS08145 29947d62931733f447beb471dacd4b4b 64 Pfam PF02597 ThiS family 2 64 8.8E-12 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CWR56_RS08145 29947d62931733f447beb471dacd4b4b 64 SUPERFAMILY SSF54285 1 63 1.26E-17 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CWR56_RS01595 d26be3c2eb5483ff0a0a4e256024a50f 242 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 5 205 1.8E-50 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CWR56_RS01595 d26be3c2eb5483ff0a0a4e256024a50f 242 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 194 1.2E-28 T 29-03-2018 CWR56_RS01595 d26be3c2eb5483ff0a0a4e256024a50f 242 SUPERFAMILY SSF56784 1 232 3.99E-28 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01595 d26be3c2eb5483ff0a0a4e256024a50f 242 Gene3D G3DSA:3.40.50.1000 2 229 1.8E-16 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01595 d26be3c2eb5483ff0a0a4e256024a50f 242 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 192 4.9E-19 T 29-03-2018 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 SUPERFAMILY SSF47413 11 72 2.13E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 SUPERFAMILY SSF53822 73 339 7.25E-58 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 Pfam PF13377 Periplasmic binding protein-like domain 179 339 3.5E-31 T 29-03-2018 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 Gene3D G3DSA:1.10.260.40 12 65 2.7E-17 T 29-03-2018 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 SMART SM00354 11 83 2.5E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 1.6E-12 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 Gene3D G3DSA:3.40.50.2300 66 185 1.4E-28 T 29-03-2018 CWR56_RS03270 f9755530e9cfbe2b260582b6f6cfb9f0 340 Gene3D G3DSA:3.40.50.2300 186 340 3.8E-37 T 29-03-2018 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 Pfam PF12833 Helix-turn-helix domain 151 227 6.4E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 Gene3D G3DSA:1.10.10.60 177 231 1.7E-11 T 29-03-2018 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 Gene3D G3DSA:1.10.10.60 134 176 4.2E-11 T 29-03-2018 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 Pfam PF00072 Response regulator receiver domain 5 116 3.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 SUPERFAMILY SSF52172 1 153 5.27E-29 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 Gene3D G3DSA:3.40.50.2300 2 133 3.7E-26 T 29-03-2018 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 SMART SM00342 144 227 9.7E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 SMART SM00448 2 116 4.2E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS14410 75892b94c9600974e947d40ee71e2d1c 232 SUPERFAMILY SSF46689 180 227 3.63E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS00875 572fcc9086212ef589ba833439509f95 395 SUPERFAMILY SSF53335 115 378 4.33E-79 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS00875 572fcc9086212ef589ba833439509f95 395 PIRSF PIRSF003085 3 392 1.1E-119 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CWR56_RS00875 572fcc9086212ef589ba833439509f95 395 Pfam PF02353 Mycolic acid cyclopropane synthetase 106 373 4.6E-97 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS00875 572fcc9086212ef589ba833439509f95 395 Gene3D G3DSA:3.40.50.150 102 377 7.7E-62 T 29-03-2018 CWR56_RS15370 4dfe5db5430379f8fca82c73cac59673 306 Pfam PF00294 pfkB family carbohydrate kinase 11 288 6.3E-43 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CWR56_RS15370 4dfe5db5430379f8fca82c73cac59673 306 Gene3D G3DSA:3.40.1190.20 43 306 1.0E-32 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS15370 4dfe5db5430379f8fca82c73cac59673 306 Gene3D G3DSA:2.20.150.10 9 42 1.8E-8 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWR56_RS15370 4dfe5db5430379f8fca82c73cac59673 306 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 302 1.0E-84 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR56_RS15370 4dfe5db5430379f8fca82c73cac59673 306 PIRSF PIRSF000535 1 305 3.2E-65 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR56_RS15370 4dfe5db5430379f8fca82c73cac59673 306 SUPERFAMILY SSF53613 1 287 9.04E-59 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS07025 0b9d793801cb53766c0875d8ad9ebf09 263 SUPERFAMILY SSF53850 29 263 1.36E-82 T 29-03-2018 CWR56_RS07025 0b9d793801cb53766c0875d8ad9ebf09 263 Gene3D G3DSA:3.40.190.10 26 123 7.6E-23 T 29-03-2018 CWR56_RS07025 0b9d793801cb53766c0875d8ad9ebf09 263 Gene3D G3DSA:3.40.190.10 124 263 1.5E-52 T 29-03-2018 CWR56_RS07025 0b9d793801cb53766c0875d8ad9ebf09 263 Pfam PF03180 NLPA lipoprotein 30 263 1.0E-92 T 29-03-2018 IPR004872 Lipoprotein NlpA family CWR56_RS07025 0b9d793801cb53766c0875d8ad9ebf09 263 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 11 262 1.6E-68 T 29-03-2018 IPR004872 Lipoprotein NlpA family CWR56_RS07025 0b9d793801cb53766c0875d8ad9ebf09 263 PIRSF PIRSF002854 1 263 1.4E-101 T 29-03-2018 IPR004872 Lipoprotein NlpA family CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 SUPERFAMILY SSF56014 227 314 3.18E-32 T 29-03-2018 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 SUPERFAMILY SSF56014 103 167 3.18E-32 T 29-03-2018 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 Pfam PF14697 4Fe-4S dicluster domain 170 218 3.2E-9 T 29-03-2018 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 Gene3D G3DSA:3.30.413.10 114 319 7.0E-31 T 29-03-2018 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 19 81 6.2E-18 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 Gene3D G3DSA:3.90.480.10 26 113 1.0E-10 T 29-03-2018 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 206 217 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 SUPERFAMILY SSF55124 16 81 1.39E-16 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 145 161 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 PRINTS PR00397 Sirohaem Fe-binding site signature 145 163 1.7E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 PRINTS PR00397 Sirohaem Fe-binding site signature 104 122 1.7E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 101 301 1.2E-25 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 TIGRFAM TIGR02912 sulfite_red_C: sulfite reductase, subunit C 4 317 1.0E-161 T 29-03-2018 IPR014261 Sulphite reductase, subunit C CWR56_RS10795 52015e1014b1a2f87eccf6c719a0c6f6 323 SUPERFAMILY SSF54862 147 232 5.09E-19 T 29-03-2018 CWR56_RS13145 dcb2e54ae6fedf33b6f2b758fb4c7acb 160 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 95 119 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CWR56_RS13145 dcb2e54ae6fedf33b6f2b758fb4c7acb 160 SUPERFAMILY SSF57716 92 122 6.84E-6 T 29-03-2018 CWR56_RS13145 dcb2e54ae6fedf33b6f2b758fb4c7acb 160 SUPERFAMILY SSF109635 3 91 2.48E-9 T 29-03-2018 CWR56_RS13145 dcb2e54ae6fedf33b6f2b758fb4c7acb 160 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 90 123 1.2E-7 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 Pfam PF06445 GyrI-like small molecule binding domain 185 267 2.8E-6 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 Gene3D G3DSA:1.10.1660.10 1 117 7.4E-21 T 29-03-2018 CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 SMART SM00871 112 268 1.4E-8 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 SUPERFAMILY SSF46955 5 110 1.17E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 SMART SM00422 5 73 5.4E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 SUPERFAMILY SSF55136 119 267 2.17E-14 T 29-03-2018 CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 Gene3D G3DSA:3.20.80.10 118 269 2.5E-19 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS06680 c18b9246efe8865a5a65a126bddee555 269 Pfam PF13411 MerR HTH family regulatory protein 5 71 2.6E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18900 d0a098b81d1dc068e45e51a1cdcc31aa 317 Pfam PF04545 Sigma-70, region 4 15 47 6.3E-8 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18900 d0a098b81d1dc068e45e51a1cdcc31aa 317 Gene3D G3DSA:1.10.10.60 1 54 1.5E-16 T 29-03-2018 CWR56_RS18900 d0a098b81d1dc068e45e51a1cdcc31aa 317 SUPERFAMILY SSF46785 18 54 4.08E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18900 d0a098b81d1dc068e45e51a1cdcc31aa 317 SUPERFAMILY SSF100950 63 314 4.88E-67 T 29-03-2018 CWR56_RS18900 d0a098b81d1dc068e45e51a1cdcc31aa 317 Gene3D G3DSA:3.40.50.1360 55 317 6.0E-39 T 29-03-2018 CWR56_RS18900 d0a098b81d1dc068e45e51a1cdcc31aa 317 Pfam PF04198 Putative sugar-binding domain 64 314 3.0E-70 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CWR56_RS04120 552f262dd8225fa7194be145b1ed37df 391 Gene3D G3DSA:3.40.140.20 28 172 4.0E-49 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS04120 552f262dd8225fa7194be145b1ed37df 391 Gene3D G3DSA:3.40.140.20 173 381 2.2E-68 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS04120 552f262dd8225fa7194be145b1ed37df 391 Pfam PF01808 AICARFT/IMPCHase bienzyme 3 260 1.0E-62 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS04120 552f262dd8225fa7194be145b1ed37df 391 SUPERFAMILY SSF53927 3 391 1.5E-133 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS04120 552f262dd8225fa7194be145b1ed37df 391 SMART SM00798 1 261 1.4E-49 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS07075 6ac3f8e558227250d792a40568405851 372 Pfam PF07282 Putative transposase DNA-binding domain 291 361 1.4E-25 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS07075 6ac3f8e558227250d792a40568405851 372 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 245 312 7.4E-15 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS07075 6ac3f8e558227250d792a40568405851 372 Pfam PF12323 Helix-turn-helix domain 4 48 8.3E-22 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CWR56_RS07075 6ac3f8e558227250d792a40568405851 372 Pfam PF01385 Probable transposase 176 277 2.0E-24 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CWR56_RS04455 a0710377bee098fa5487f423d409c776 209 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 8 197 1.3E-28 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CWR56_RS04455 a0710377bee098fa5487f423d409c776 209 SUPERFAMILY SSF56784 1 202 2.83E-17 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS04455 a0710377bee098fa5487f423d409c776 209 Gene3D G3DSA:3.40.50.1000 1 208 2.4E-10 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS04455 a0710377bee098fa5487f423d409c776 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 187 7.6E-28 T 29-03-2018 CWR56_RS04455 a0710377bee098fa5487f423d409c776 209 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 189 5.2E-18 T 29-03-2018 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Gene3D G3DSA:1.10.1790.10 291 394 3.2E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 SUPERFAMILY SSF55804 499 636 1.44E-25 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Pfam PF00874 PRD domain 302 389 1.0E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 SUPERFAMILY SSF63520 292 393 6.67E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Gene3D G3DSA:1.10.1790.10 185 282 0.04 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Pfam PF08279 HTH domain 7 65 5.4E-8 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Pfam PF05043 Mga helix-turn-helix domain 95 167 4.0E-9 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Gene3D G3DSA:1.10.10.10 90 155 3.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Gene3D G3DSA:1.10.10.10 3 69 1.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Gene3D G3DSA:3.40.930.10 496 636 8.6E-25 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 509 628 2.5E-21 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS00640 06bc1434c44d1fe77688ec2bdf99cd91 637 Gene3D G3DSA:3.40.50.2300 399 488 1.6E-12 T 29-03-2018 CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 85 199 2.0E-18 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 Pfam PF00990 Diguanylate cyclase, GGDEF domain 89 195 5.8E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 SUPERFAMILY SSF141868 253 501 5.1E-77 T 29-03-2018 IPR001633 EAL domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 SMART SM00052 248 494 1.3E-74 T 29-03-2018 IPR001633 EAL domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 SUPERFAMILY SSF55073 95 240 1.49E-22 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 Pfam PF00563 EAL domain 255 489 1.3E-61 T 29-03-2018 IPR001633 EAL domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 Gene3D G3DSA:3.20.20.450 245 498 2.8E-81 T 29-03-2018 IPR001633 EAL domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 SMART SM00267 78 238 2.4E-7 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08880 3c753bf8d53f6af52125819c8c2570ef 502 Gene3D G3DSA:3.30.70.270 83 244 9.2E-26 T 29-03-2018 CWR56_RS00930 be46b5fbcb2e727a866ee5057fda2af0 194 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 5 187 1.0E-66 T 29-03-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS00930 be46b5fbcb2e727a866ee5057fda2af0 194 Pfam PF00156 Phosphoribosyl transferase domain 46 160 2.0E-12 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS00930 be46b5fbcb2e727a866ee5057fda2af0 194 SUPERFAMILY SSF53271 9 148 8.38E-36 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS00930 be46b5fbcb2e727a866ee5057fda2af0 194 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 194 23.496 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR56_RS00930 be46b5fbcb2e727a866ee5057fda2af0 194 Gene3D G3DSA:3.40.50.2020 1 154 1.8E-25 T 29-03-2018 CWR56_RS01510 6412d13f9a06e5bf4376a31c511cf1ab 305 SMART SM00382 28 208 1.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01510 6412d13f9a06e5bf4376a31c511cf1ab 305 Pfam PF00005 ABC transporter 20 162 2.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01510 6412d13f9a06e5bf4376a31c511cf1ab 305 Gene3D G3DSA:3.40.50.300 1 283 4.0E-61 T 29-03-2018 CWR56_RS01510 6412d13f9a06e5bf4376a31c511cf1ab 305 Pfam PF13732 Domain of unknown function (DUF4162) 214 304 5.6E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CWR56_RS01510 6412d13f9a06e5bf4376a31c511cf1ab 305 SUPERFAMILY SSF52540 3 226 2.83E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00085 a813e158211a2b368f85e4d207030f3d 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 202 1.8E-87 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00085 a813e158211a2b368f85e4d207030f3d 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 100 123 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site CWR56_RS00085 a813e158211a2b368f85e4d207030f3d 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 205 39.205 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00085 a813e158211a2b368f85e4d207030f3d 209 Pfam PF00297 Ribosomal protein L3 94 180 3.6E-16 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00085 a813e158211a2b368f85e4d207030f3d 209 Gene3D G3DSA:4.10.960.10 57 163 8.9E-36 T 29-03-2018 CWR56_RS00085 a813e158211a2b368f85e4d207030f3d 209 SUPERFAMILY SSF50447 1 207 1.32E-79 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS02460 40b565a8e5d9e653e388436361ebd770 172 Pfam PF01584 CheW-like domain 20 154 9.6E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02460 40b565a8e5d9e653e388436361ebd770 172 Gene3D G3DSA:2.30.30.40 101 132 1.5E-14 T 29-03-2018 CWR56_RS02460 40b565a8e5d9e653e388436361ebd770 172 SUPERFAMILY SSF50341 16 155 4.32E-33 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02460 40b565a8e5d9e653e388436361ebd770 172 SMART SM00260 15 152 1.8E-24 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02460 40b565a8e5d9e653e388436361ebd770 172 Gene3D G3DSA:2.40.50.180 133 162 0.077 T 29-03-2018 CWR56_RS02460 40b565a8e5d9e653e388436361ebd770 172 Gene3D G3DSA:2.40.50.180 34 100 1.5E-14 T 29-03-2018 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 Gene3D G3DSA:3.40.50.720 7 151 6.4E-28 T 29-03-2018 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 313 5.5E-109 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 PRINTS PR00086 L-lactate dehydrogenase signature 178 191 9.8E-38 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 PRINTS PR00086 L-lactate dehydrogenase signature 148 166 9.8E-38 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 PRINTS PR00086 L-lactate dehydrogenase signature 124 144 9.8E-38 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 9.8E-38 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 9.8E-38 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 SUPERFAMILY SSF56327 151 317 2.65E-53 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 180 186 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 153 317 5.3E-27 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 150 2.9E-32 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 SUPERFAMILY SSF51735 3 152 1.66E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 PIRSF PIRSF000102 2 321 4.3E-101 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 320 39.42 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWR56_RS10435 b4d99f9a790c2c93b74fac80e00b501b 322 Gene3D G3DSA:3.90.110.10 152 321 5.7E-43 T 29-03-2018 CWR56_RS14800 dad4dcaf483099e1de6a4cf71076aafa 88 Pfam PF09827 CRISPR associated protein Cas2 1 68 6.3E-23 T 29-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CWR56_RS14800 dad4dcaf483099e1de6a4cf71076aafa 88 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 88 15.633 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CWR56_RS14800 dad4dcaf483099e1de6a4cf71076aafa 88 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 81 1.0E-14 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CWR56_RS14800 dad4dcaf483099e1de6a4cf71076aafa 88 Gene3D G3DSA:3.30.70.240 1 87 2.5E-25 T 29-03-2018 CWR56_RS14800 dad4dcaf483099e1de6a4cf71076aafa 88 SUPERFAMILY SSF143430 1 83 2.49E-24 T 29-03-2018 CWR56_RS08750 ae47594a69486d6722ae0f692c794a81 213 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CWR56_RS08750 ae47594a69486d6722ae0f692c794a81 213 SUPERFAMILY SSF53254 4 202 1.96E-60 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CWR56_RS08750 ae47594a69486d6722ae0f692c794a81 213 Gene3D G3DSA:3.40.50.1240 2 212 3.1E-57 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CWR56_RS08750 ae47594a69486d6722ae0f692c794a81 213 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 5.0E-61 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR56_RS08750 ae47594a69486d6722ae0f692c794a81 213 PIRSF PIRSF000709 2 212 1.6E-22 T 29-03-2018 CWR56_RS08750 ae47594a69486d6722ae0f692c794a81 213 SMART SM00855 4 158 4.5E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 SUPERFAMILY SSF52540 3 214 3.72E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 SUPERFAMILY SSF48019 223 342 8.5E-21 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 338 1.5E-52 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 Gene3D G3DSA:3.40.50.300 1 142 7.3E-25 T 29-03-2018 CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 Gene3D G3DSA:1.10.8.60 146 230 6.1E-14 T 29-03-2018 CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 Pfam PF06144 DNA polymerase III, delta subunit 19 197 8.6E-31 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CWR56_RS12505 b4c646c9a15f37bfe751a17b034fa0aa 347 Gene3D G3DSA:1.20.272.10 231 346 2.1E-28 T 29-03-2018 CWR56_RS17055 731e04342bdba176de00fa8ba5522af0 250 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 246 2.1E-74 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CWR56_RS17055 731e04342bdba176de00fa8ba5522af0 250 Gene3D G3DSA:3.40.50.2300 65 241 1.0E-6 T 29-03-2018 CWR56_RS17055 731e04342bdba176de00fa8ba5522af0 250 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 247 3.0E-62 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 Pfam PF01895 PhoU domain 448 531 7.3E-14 T 29-03-2018 IPR026022 PhoU domain CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 Pfam PF01895 PhoU domain 343 428 2.0E-13 T 29-03-2018 IPR026022 PhoU domain CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 Gene3D G3DSA:1.20.58.220 443 538 1.9E-19 T 29-03-2018 CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 Gene3D G3DSA:1.20.58.220 325 442 4.8E-20 T 29-03-2018 CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 Pfam PF02690 Na+/Pi-cotransporter 13 148 2.6E-53 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 Pfam PF02690 Na+/Pi-cotransporter 143 263 4.9E-20 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 SUPERFAMILY SSF109755 323 533 9.0E-49 T 29-03-2018 CWR56_RS08280 d976fcd49a2b7dda438762f20fce1264 539 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 2 308 3.8E-78 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 SMART SM00287 32 95 3.6E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 SMART SM00287 207 271 3.7E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 SMART SM00287 114 178 2.1E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Pfam PF08239 Bacterial SH3 domain 217 268 1.4E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Pfam PF08239 Bacterial SH3 domain 40 92 2.3E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Pfam PF08239 Bacterial SH3 domain 123 175 8.6E-17 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Gene3D G3DSA:2.40.50.110 21 94 2.6E-17 T 29-03-2018 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 SUPERFAMILY SSF50044 237 284 2.99E-6 T 29-03-2018 IPR001452 SH3 domain GO:0005515 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Pfam PF00877 NlpC/P60 family 319 429 1.6E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 SUPERFAMILY SSF54001 304 430 1.03E-40 T 29-03-2018 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Gene3D G3DSA:3.90.1720.10 295 431 7.6E-40 T 29-03-2018 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 SUPERFAMILY SSF50044 144 181 2.53E-5 T 29-03-2018 IPR001452 SH3 domain GO:0005515 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Gene3D G3DSA:2.30.30.410 95 185 1.8E-20 T 29-03-2018 CWR56_RS05145 d29e499d25e0b6d00b541d6cb3172cb3 431 Gene3D G3DSA:2.30.30.410 186 281 2.4E-21 T 29-03-2018 CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 SUPERFAMILY SSF46894 129 229 6.8E-33 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 Gene3D G3DSA:3.40.50.2300 1 126 1.8E-33 T 29-03-2018 CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 Pfam PF00072 Response regulator receiver domain 5 116 3.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 Gene3D G3DSA:1.10.10.10 127 230 3.4E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 1.7E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 SMART SM00862 153 229 5.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 SUPERFAMILY SSF52172 2 126 1.71E-41 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS13350 66e6be756a6325a5e6ece63c56be1c26 230 SMART SM00448 3 116 1.4E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 PIRSF PIRSF000538 1 504 3.1E-156 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 SUPERFAMILY SSF53067 256 499 1.44E-77 T 29-03-2018 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 2 498 2.6E-191 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 Gene3D G3DSA:3.30.420.40 1 251 7.2E-75 T 29-03-2018 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 SUPERFAMILY SSF53067 2 257 1.13E-85 T 29-03-2018 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 452 4.4E-51 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 Gene3D G3DSA:3.30.420.40 252 503 1.3E-68 T 29-03-2018 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 254 2.3E-73 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR56_RS03590 502de123864a06bb82f9a5bd6b0b9098 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 137 149 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS06695 d36f0ab410d2a0a3bb0f8a56aefa305d 224 Pfam PF02308 MgtC family 16 140 7.3E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS06695 d36f0ab410d2a0a3bb0f8a56aefa305d 224 PRINTS PR01837 MgtC/SapB protein signature 98 122 5.9E-44 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS06695 d36f0ab410d2a0a3bb0f8a56aefa305d 224 PRINTS PR01837 MgtC/SapB protein signature 18 37 5.9E-44 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS06695 d36f0ab410d2a0a3bb0f8a56aefa305d 224 PRINTS PR01837 MgtC/SapB protein signature 37 55 5.9E-44 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS06695 d36f0ab410d2a0a3bb0f8a56aefa305d 224 PRINTS PR01837 MgtC/SapB protein signature 71 93 5.9E-44 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 189 2.3E-23 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 2 189 6.7E-64 T 29-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 2 190 6.8E-81 T 29-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 61 189 7.3E-16 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 Gene3D G3DSA:1.10.150.240 18 82 1.5E-20 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 SUPERFAMILY SSF56784 1 208 2.56E-43 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS10565 26583d3b9e55b326d4701923bcb945b7 226 Gene3D G3DSA:3.40.50.1000 83 222 3.4E-20 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS00970 8e1ddb8d455f6b4286af3c55ad7a3924 246 SUPERFAMILY SSF52255 117 245 3.4E-29 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS00970 8e1ddb8d455f6b4286af3c55ad7a3924 246 SMART SM01001 117 246 8.4E-33 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS00970 8e1ddb8d455f6b4286af3c55ad7a3924 246 Pfam PF00731 AIR carboxylase 118 243 1.5E-16 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS00970 8e1ddb8d455f6b4286af3c55ad7a3924 246 Gene3D G3DSA:3.40.50.7700 109 246 1.1E-37 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS09450 24c4ff8965ab819259112b15a6f82cd8 118 SUPERFAMILY SSF46785 18 117 1.45E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09450 24c4ff8965ab819259112b15a6f82cd8 118 Gene3D G3DSA:1.10.10.10 28 118 5.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09450 24c4ff8965ab819259112b15a6f82cd8 118 Pfam PF01638 HxlR-like helix-turn-helix 30 117 1.2E-28 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS00210 8761c5f3497ac6373cbcc02bd0e0c3c8 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00210 8761c5f3497ac6373cbcc02bd0e0c3c8 37 SUPERFAMILY SSF57840 1 37 9.81E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00210 8761c5f3497ac6373cbcc02bd0e0c3c8 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 3.0E-8 T 29-03-2018 CWR56_RS00210 8761c5f3497ac6373cbcc02bd0e0c3c8 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.381 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00210 8761c5f3497ac6373cbcc02bd0e0c3c8 37 Pfam PF00444 Ribosomal protein L36 1 37 1.0E-18 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00210 8761c5f3497ac6373cbcc02bd0e0c3c8 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 6.9E-24 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS06045 11646b2fc08be6c40d80793bb686f0dc 106 Gene3D G3DSA:1.10.287.1080 9 106 2.7E-12 T 29-03-2018 CWR56_RS06045 11646b2fc08be6c40d80793bb686f0dc 106 SUPERFAMILY SSF101386 16 98 4.1E-7 T 29-03-2018 CWR56_RS06045 11646b2fc08be6c40d80793bb686f0dc 106 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 18 98 1.5E-5 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR56_RS09770 8ce845804ffa24d96f15880d5c88978c 185 SUPERFAMILY SSF48498 76 180 3.07E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR56_RS09770 8ce845804ffa24d96f15880d5c88978c 185 SUPERFAMILY SSF46689 2 68 4.74E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09770 8ce845804ffa24d96f15880d5c88978c 185 Gene3D G3DSA:1.10.10.60 2 55 2.9E-10 T 29-03-2018 CWR56_RS09770 8ce845804ffa24d96f15880d5c88978c 185 Gene3D G3DSA:1.10.357.10 56 182 1.5E-8 T 29-03-2018 CWR56_RS09770 8ce845804ffa24d96f15880d5c88978c 185 Pfam PF13305 WHG domain 83 158 1.8E-7 T 29-03-2018 IPR025996 WHG domain CWR56_RS05585 97374d7e655f0ddc902cc792274cc363 304 Gene3D G3DSA:1.10.443.10 108 286 1.6E-32 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS05585 97374d7e655f0ddc902cc792274cc363 304 Pfam PF00589 Phage integrase family 108 276 1.1E-34 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS05585 97374d7e655f0ddc902cc792274cc363 304 Gene3D G3DSA:1.10.150.130 1 107 1.8E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS05585 97374d7e655f0ddc902cc792274cc363 304 SUPERFAMILY SSF56349 2 285 1.35E-49 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS05585 97374d7e655f0ddc902cc792274cc363 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 83 4.2E-16 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR56_RS04520 6db1a9afc4177f0e68b7b7d0844d9fc5 416 PIRSF PIRSF033563 1 416 3.1E-141 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 CWR56_RS04520 6db1a9afc4177f0e68b7b7d0844d9fc5 416 Pfam PF06245 Protein of unknown function (DUF1015) 4 412 5.8E-132 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 CWR56_RS14265 bf3b23bbd84147731eef40eb20e30e2b 478 SUPERFAMILY SSF142764 38 476 3.27E-65 T 29-03-2018 CWR56_RS14265 bf3b23bbd84147731eef40eb20e30e2b 478 Gene3D G3DSA:3.40.50.10840 37 287 3.9E-57 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CWR56_RS14265 bf3b23bbd84147731eef40eb20e30e2b 478 Pfam PF07005 Putative sugar-binding N-terminal domain 38 280 2.4E-50 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CWR56_RS14265 bf3b23bbd84147731eef40eb20e30e2b 478 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 305 469 2.9E-34 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CWR56_RS12530 c395a0d1f44734c756d2804cbdc3ef98 235 Pfam PF00899 ThiF family 12 222 1.0E-38 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR56_RS12530 c395a0d1f44734c756d2804cbdc3ef98 235 Gene3D G3DSA:3.40.50.720 1 235 5.6E-45 T 29-03-2018 CWR56_RS12530 c395a0d1f44734c756d2804cbdc3ef98 235 SUPERFAMILY SSF69572 3 235 2.35E-58 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR56_RS06980 66d6e0ce3424daada1b458b01cdb0f20 256 Gene3D G3DSA:1.10.3720.10 11 252 1.4E-27 T 29-03-2018 CWR56_RS06980 66d6e0ce3424daada1b458b01cdb0f20 256 SUPERFAMILY SSF161098 53 240 1.57E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS06980 66d6e0ce3424daada1b458b01cdb0f20 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 238 1.4E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 Pfam PF07969 Amidohydrolase family 43 248 6.8E-13 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 Pfam PF07969 Amidohydrolase family 420 511 8.1E-12 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 Gene3D G3DSA:2.30.40.10 448 516 6.7E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 SUPERFAMILY SSF51338 2 54 2.06E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 SUPERFAMILY SSF51338 466 518 2.06E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 Gene3D G3DSA:2.30.40.10 1 67 5.1E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 Gene3D G3DSA:3.20.20.140 68 447 2.8E-71 T 29-03-2018 CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 SUPERFAMILY SSF51556 55 293 6.12E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS15975 fb7f82f17425f3f2499decaa4b1c1122 527 SUPERFAMILY SSF51556 335 466 6.12E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 3.5E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 3.5E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 3.5E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 3.5E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 3.5E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 3.5E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 SUPERFAMILY SSF53697 5 447 3.44E-141 T 29-03-2018 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 Gene3D G3DSA:3.40.50.10490 61 207 6.1E-45 T 29-03-2018 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 Pfam PF00342 Phosphoglucose isomerase 76 426 1.6E-21 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 25.917 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 Gene3D G3DSA:3.40.50.10490 208 434 2.6E-73 T 29-03-2018 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 Gene3D G3DSA:3.40.50.10490 1 60 2.6E-11 T 29-03-2018 CWR56_RS16520 49f264d39ffd5070a63babdb8fc28f7a 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS12835 22d4ddcb103528d25f564ab955a8b3b0 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 299 7.0E-96 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CWR56_RS12835 22d4ddcb103528d25f564ab955a8b3b0 305 Hamap MF_01818 Ribonuclease BN [rbn]. 2 301 31.673 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CWR56_RS12835 22d4ddcb103528d25f564ab955a8b3b0 305 SUPERFAMILY SSF56281 4 301 5.5E-64 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12835 22d4ddcb103528d25f564ab955a8b3b0 305 Gene3D G3DSA:3.60.15.10 2 305 7.9E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12835 22d4ddcb103528d25f564ab955a8b3b0 305 Pfam PF00753 Metallo-beta-lactamase superfamily 21 85 8.8E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05500 dd9d4b87335d18731a746f2edc1e6279 295 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWR56_RS05500 dd9d4b87335d18731a746f2edc1e6279 295 SUPERFAMILY SSF48576 4 285 3.24E-84 T 29-03-2018 IPR008949 Isoprenoid synthase domain CWR56_RS05500 dd9d4b87335d18731a746f2edc1e6279 295 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 214 226 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWR56_RS05500 dd9d4b87335d18731a746f2edc1e6279 295 Gene3D G3DSA:1.10.600.10 1 295 1.3E-91 T 29-03-2018 IPR008949 Isoprenoid synthase domain CWR56_RS05500 dd9d4b87335d18731a746f2edc1e6279 295 Pfam PF00348 Polyprenyl synthetase 31 274 1.4E-57 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CWR56_RS11555 ae212e147d8cfe4f4dcf02510875ee6d 424 PIRSF PIRSF006304 4 424 7.3E-163 T 29-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 CWR56_RS11555 ae212e147d8cfe4f4dcf02510875ee6d 424 Pfam PF03611 PTS system sugar-specific permease component 10 389 4.3E-93 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWR56_RS11555 ae212e147d8cfe4f4dcf02510875ee6d 424 TIGRFAM TIGR00827 EIIC-GAT: PTS system, galactitol-specific IIC component 11 414 3.8E-165 T 29-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 CWR56_RS10775 b3e32487bc2c901759b07ebe5938ac51 285 Gene3D G3DSA:3.20.20.70 4 279 5.0E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10775 b3e32487bc2c901759b07ebe5938ac51 285 SMART SM00729 11 229 2.8E-39 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS10775 b3e32487bc2c901759b07ebe5938ac51 285 Pfam PF04055 Radical SAM superfamily 16 177 2.4E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS10775 b3e32487bc2c901759b07ebe5938ac51 285 SUPERFAMILY SSF102114 2 236 1.2E-42 T 29-03-2018 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 Pfam PF03123 CAT RNA binding domain 1 56 2.3E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 SUPERFAMILY SSF63520 60 167 2.09E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 SUPERFAMILY SSF63520 176 273 6.93E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 SUPERFAMILY SSF50151 1 54 2.09E-15 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 Gene3D G3DSA:2.30.24.10 1 51 3.5E-19 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 SMART SM01061 1 59 6.6E-24 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 Pfam PF00874 PRD domain 182 273 5.3E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 Pfam PF00874 PRD domain 77 163 9.4E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 Gene3D G3DSA:1.10.1790.10 165 278 1.5E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS04010 55d485393f9a27857ad8834fc3bd0123 282 Gene3D G3DSA:1.10.1790.10 52 164 1.1E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 329 3.6E-127 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 SUPERFAMILY SSF51735 119 293 2.97E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 Pfam PF00107 Zinc-binding dehydrogenase 161 273 1.5E-10 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 SUPERFAMILY SSF50129 5 142 1.35E-39 T 29-03-2018 IPR011032 GroES-like CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 SMART SM00829 15 327 1.3E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 Gene3D G3DSA:3.40.50.720 142 326 8.4E-14 T 29-03-2018 CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 Gene3D G3DSA:3.90.180.10 1 141 1.5E-30 T 29-03-2018 CWR56_RS14435 01e63d7a0f36a24c027ccbd4a6b5efcd 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 1.8E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR56_RS09775 fc1bcd7022f71cda8ec604222a6f74d6 232 SUPERFAMILY SSF53474 11 228 8.2E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS09775 fc1bcd7022f71cda8ec604222a6f74d6 232 Gene3D G3DSA:3.40.50.1820 20 232 3.6E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS07610 8cb542f191059705387bbba0899ee05b 100 Gene3D G3DSA:3.40.50.2300 2 100 2.2E-31 T 29-03-2018 CWR56_RS07610 8cb542f191059705387bbba0899ee05b 100 SUPERFAMILY SSF52794 1 99 1.75E-32 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS07610 8cb542f191059705387bbba0899ee05b 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 93 2.8E-20 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS09715 5a2b9cebbcbc7fe3609bc724b2aac105 405 SUPERFAMILY SSF56266 12 401 4.84E-134 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS09715 5a2b9cebbcbc7fe3609bc724b2aac105 405 Pfam PF01960 ArgJ family 16 404 5.6E-148 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS09715 5a2b9cebbcbc7fe3609bc724b2aac105 405 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 405 140.634 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS09715 5a2b9cebbcbc7fe3609bc724b2aac105 405 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 4 404 1.0E-145 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS09715 5a2b9cebbcbc7fe3609bc724b2aac105 405 Gene3D G3DSA:3.60.70.12 3 274 2.3E-104 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS09715 5a2b9cebbcbc7fe3609bc724b2aac105 405 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 25 403 1.0E-105 T 29-03-2018 CWR56_RS16995 1ed9c36dab286805b6900ec53bd5db0e 434 Gene3D G3DSA:3.40.190.10 238 387 5.4E-12 T 29-03-2018 CWR56_RS16995 1ed9c36dab286805b6900ec53bd5db0e 434 Pfam PF13416 Bacterial extracellular solute-binding protein 60 365 1.3E-43 T 29-03-2018 CWR56_RS16995 1ed9c36dab286805b6900ec53bd5db0e 434 SUPERFAMILY SSF53850 43 418 2.35E-68 T 29-03-2018 CWR56_RS16995 1ed9c36dab286805b6900ec53bd5db0e 434 Gene3D G3DSA:3.40.190.10 42 228 6.6E-35 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 327 350 2.8E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 224 264 2.7E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 189 223 0.18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:2.60.40.1180 103 121 2.0E-5 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:2.60.40.1180 265 283 0.0041 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 8 102 2.6E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SUPERFAMILY SSF81901 248 473 4.71E-31 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SUPERFAMILY SSF81901 441 541 1.62E-16 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 284 326 1.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 351 383 4.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 384 460 6.7E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SUPERFAMILY SSF81901 18 217 4.45E-32 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 157 188 0.015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 122 156 4.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Gene3D G3DSA:1.25.40.10 461 569 2.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 368 397 46.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 497 530 0.0092 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 146 179 0.11 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 400 433 0.12 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 210 241 260.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 306 339 0.71 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 242 275 0.044 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 50 83 0.27 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00028 114 145 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF13181 Tetratricopeptide repeat 401 424 5.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF13181 Tetratricopeptide repeat 498 525 6.1E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF13181 Tetratricopeptide repeat 372 396 1.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF13181 Tetratricopeptide repeat 147 171 0.0055 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF08238 Sel1 repeat 245 273 4.2 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF08238 Sel1 repeat 128 144 10.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF08238 Sel1 repeat 225 241 37.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF08238 Sel1 repeat 478 495 17.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF08238 Sel1 repeat 290 302 120.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF08238 Sel1 repeat 180 209 87.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 114 145 9.3 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 497 528 4.9 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 242 273 3.9 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 50 81 0.1 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 368 399 0.033 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 178 209 180.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 274 305 21.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 306 337 2.4 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 82 113 8.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 146 177 12.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 400 431 6.2 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 210 241 0.23 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 SMART SM00671 464 496 12.0 T 29-03-2018 IPR006597 Sel1-like repeat CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF13432 Tetratricopeptide repeat 25 83 8.0E-4 T 29-03-2018 CWR56_RS10210 c9a4450625ac6aeefffb3b694d9cf593 623 Pfam PF13432 Tetratricopeptide repeat 311 363 3.4E-7 T 29-03-2018 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 134 220 8.7E-18 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 65 118 1.0E-17 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 SUPERFAMILY SSF141734 17 124 9.55E-48 T 29-03-2018 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 SUPERFAMILY SSF101386 132 221 2.06E-25 T 29-03-2018 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 18 222 36.7 T 29-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 42 115 6.9E-34 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 Gene3D G3DSA:1.10.287.1080 130 222 2.5E-21 T 29-03-2018 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 134 217 1.0E-32 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 16 119 29.805 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CWR56_RS07370 689985769da38f8e1fa173b023fef0bc 222 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 131 217 21.903 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 SUPERFAMILY SSF47384 75 155 7.46E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 Pfam PF00512 His Kinase A (phospho-acceptor) domain 88 154 9.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 Gene3D G3DSA:3.30.565.10 149 305 2.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 SMART SM00387 200 305 7.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 201 304 4.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 SUPERFAMILY SSF55874 143 304 1.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 Gene3D G3DSA:1.10.287.130 75 148 4.5E-11 T 29-03-2018 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 SMART SM00388 85 154 1.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 PRINTS PR00344 Bacterial sensor protein C-terminal signature 267 285 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 265 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 304 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS03040 babcb9a62009849a7b2b7c98a0f052f6 305 PRINTS PR00344 Bacterial sensor protein C-terminal signature 237 251 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS11900 86ca79e6a481f82dff3c154240dee93f 67 Pfam PF01381 Helix-turn-helix 5 59 2.3E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11900 86ca79e6a481f82dff3c154240dee93f 67 SMART SM00530 4 59 1.1E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11900 86ca79e6a481f82dff3c154240dee93f 67 Gene3D G3DSA:1.10.260.40 1 67 5.7E-20 T 29-03-2018 CWR56_RS11900 86ca79e6a481f82dff3c154240dee93f 67 SUPERFAMILY SSF47413 2 65 9.65E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 Gene3D G3DSA:1.10.4030.10 20 156 2.6E-16 T 29-03-2018 CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 222 242 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 SUPERFAMILY SSF109998 26 206 1.69E-27 T 29-03-2018 IPR027304 Trigger factor/SurA domain CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 SUPERFAMILY SSF54534 177 284 2.62E-34 T 29-03-2018 CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 Gene3D G3DSA:3.10.50.40 169 307 1.3E-43 T 29-03-2018 CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 Pfam PF13616 PPIC-type PPIASE domain 164 283 3.3E-34 T 29-03-2018 CWR56_RS17455 d44e05de95844fd0867723525a56c6af 331 Pfam PF13624 SurA N-terminal domain 5 149 1.9E-19 T 29-03-2018 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Gene3D G3DSA:3.60.20.10 2 240 1.1E-68 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.815 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Gene3D G3DSA:3.40.50.10490 455 610 1.2E-47 T 29-03-2018 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Pfam PF13522 Glutamine amidotransferase domain 65 193 2.5E-22 T 29-03-2018 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Pfam PF01380 SIS domain 465 592 5.6E-26 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Pfam PF01380 SIS domain 291 417 1.2E-30 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 4.5E-250 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 SUPERFAMILY SSF56235 2 237 1.72E-72 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 Gene3D G3DSA:3.40.50.10490 241 454 7.3E-66 T 29-03-2018 CWR56_RS00570 e182763b68027024bb016ac113b2b5df 610 SUPERFAMILY SSF53697 247 610 1.02E-110 T 29-03-2018 CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 Gene3D G3DSA:1.50.10.10 183 309 2.6E-7 T 29-03-2018 CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 SUPERFAMILY SSF52833 6 151 4.68E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 PIRSF PIRSF006402 2 677 2.8E-236 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 SUPERFAMILY SSF48208 193 536 2.64E-80 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 Pfam PF03190 Protein of unknown function, DUF255 8 169 6.4E-77 T 29-03-2018 IPR004879 Domain of unknown function DUF255 CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 Gene3D G3DSA:3.40.30.10 5 177 9.3E-34 T 29-03-2018 CWR56_RS07435 fd579911030c190f703f169cd9f8c3b1 678 Gene3D G3DSA:1.50.10.10 310 597 4.6E-52 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Gene3D G3DSA:3.60.15.10 1 259 3.8E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Gene3D G3DSA:2.20.28.10 405 443 2.3E-5 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 SUPERFAMILY SSF52218 256 400 2.1E-28 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 597 622 2.1E-13 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 683 697 2.1E-13 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 722 729 2.1E-13 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 458 480 2.1E-13 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 SUPERFAMILY SSF56281 4 248 1.44E-51 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 460 735 1.4E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Gene3D G3DSA:3.40.50.360 260 399 5.0E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Gene3D G3DSA:3.50.50.60 444 551 9.8E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 SUPERFAMILY SSF57802 408 446 6.56E-9 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Gene3D G3DSA:3.50.50.60 552 691 1.2E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 SUPERFAMILY SSF51905 460 755 3.24E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 SMART SM00849 36 229 1.8E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Gene3D G3DSA:3.50.50.60 698 757 3.1E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 552 570 2.3E-23 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 597 615 2.3E-23 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 682 698 2.3E-23 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 478 2.3E-23 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 707 729 2.3E-23 T 29-03-2018 CWR56_RS07715 5da82597f1da88ddd5a64ddc3ef11e64 843 Pfam PF00753 Metallo-beta-lactamase superfamily 37 196 6.9E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS08540 90e29e32ceaeb67e9e1c4356ddacc347 267 Gene3D G3DSA:3.40.190.10 8 168 1.6E-31 T 29-03-2018 CWR56_RS08540 90e29e32ceaeb67e9e1c4356ddacc347 267 Gene3D G3DSA:3.40.190.10 169 266 1.2E-14 T 29-03-2018 CWR56_RS08540 90e29e32ceaeb67e9e1c4356ddacc347 267 SUPERFAMILY SSF53850 6 266 1.59E-61 T 29-03-2018 CWR56_RS08540 90e29e32ceaeb67e9e1c4356ddacc347 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 267 1.3E-60 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS08540 90e29e32ceaeb67e9e1c4356ddacc347 267 SMART SM00062 42 267 6.8E-53 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.7E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.7E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.7E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 SMART SM00422 1 70 5.4E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 Gene3D G3DSA:1.10.1660.10 1 55 1.2E-19 T 29-03-2018 CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.7E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 SUPERFAMILY SSF46955 1 118 1.25E-32 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS16020 066efe5db170e10d842805c2c2d6223f 137 Gene3D G3DSA:1.10.1660.10 56 135 8.4E-16 T 29-03-2018 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 148 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 7.5E-52 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 156 1.4E-45 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 SUPERFAMILY SSF53098 1 156 1.06E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 Gene3D G3DSA:3.30.420.10 1 160 9.9E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 6.1E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 6.1E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 6.1E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 6.1E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 6.1E-33 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS14245 40167c6765c3a091b017b23844a04959 169 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 154 45.542 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CWR56_RS04550 0b7bf1aa66f7862986feb1c56125f292 232 Gene3D G3DSA:3.40.50.300 1 228 2.7E-49 T 29-03-2018 CWR56_RS04550 0b7bf1aa66f7862986feb1c56125f292 232 SUPERFAMILY SSF52540 6 215 6.02E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04550 0b7bf1aa66f7862986feb1c56125f292 232 Pfam PF00005 ABC transporter 23 160 3.8E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04550 0b7bf1aa66f7862986feb1c56125f292 232 SMART SM00382 30 210 7.6E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00175 dff33cc78ed889912b56212ad8c19623 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.1E-23 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00175 dff33cc78ed889912b56212ad8c19623 61 PIRSF PIRSF002211 1 60 3.2E-26 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00175 dff33cc78ed889912b56212ad8c19623 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 17.873 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00175 dff33cc78ed889912b56212ad8c19623 61 Gene3D G3DSA:3.30.1390.20 4 58 1.6E-21 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWR56_RS00175 dff33cc78ed889912b56212ad8c19623 61 SUPERFAMILY SSF55129 1 59 1.31E-18 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWR56_RS00175 dff33cc78ed889912b56212ad8c19623 61 Pfam PF00327 Ribosomal protein L30p/L7e 5 53 9.6E-18 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWR56_RS15500 6839ffb383d93b1ed6131b9b99212d1b 163 Gene3D G3DSA:2.70.70.10 1 163 7.9E-56 T 29-03-2018 CWR56_RS15500 6839ffb383d93b1ed6131b9b99212d1b 163 SUPERFAMILY SSF51261 3 140 4.88E-52 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS15500 6839ffb383d93b1ed6131b9b99212d1b 163 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 15 134 2.9E-43 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15500 6839ffb383d93b1ed6131b9b99212d1b 163 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 14 136 2.3E-50 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS12455 2bc449495c0d2d5b54e25bdd65948ced 391 Pfam PF04055 Radical SAM superfamily 6 191 2.7E-21 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS12455 2bc449495c0d2d5b54e25bdd65948ced 391 SMART SM00729 1 236 1.6E-51 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS12455 2bc449495c0d2d5b54e25bdd65948ced 391 Pfam PF06969 HemN C-terminal domain 315 379 3.0E-19 T 29-03-2018 IPR010723 HemN, C-terminal CWR56_RS12455 2bc449495c0d2d5b54e25bdd65948ced 391 Gene3D G3DSA:3.20.20.70 2 337 1.4E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS12455 2bc449495c0d2d5b54e25bdd65948ced 391 SUPERFAMILY SSF102114 3 390 1.83E-109 T 29-03-2018 CWR56_RS12455 2bc449495c0d2d5b54e25bdd65948ced 391 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 372 1.1E-96 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 Gene3D G3DSA:3.90.550.10 5 283 1.0E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 Pfam PF13489 Methyltransferase domain 284 434 4.2E-19 T 29-03-2018 CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 Gene3D G3DSA:1.25.40.10 541 613 1.5E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 Gene3D G3DSA:3.40.50.150 284 488 1.2E-25 T 29-03-2018 CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 SUPERFAMILY SSF53448 28 262 1.86E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 Pfam PF00535 Glycosyl transferase family 2 31 143 7.1E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS01215 f0e8657f9a305b7b047f3d6c523c9196 625 SUPERFAMILY SSF53335 248 460 4.18E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS08485 c96f1a5e3478f2df1041450cd471083c 233 SUPERFAMILY SSF56037 50 229 1.12E-30 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS08485 c96f1a5e3478f2df1041450cd471083c 233 SMART SM00873 62 216 1.4E-18 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS08485 c96f1a5e3478f2df1041450cd471083c 233 Gene3D G3DSA:3.50.40.10 48 220 3.5E-28 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS08485 c96f1a5e3478f2df1041450cd471083c 233 Pfam PF03483 B3/4 domain 65 206 6.7E-26 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS03820 738583f507e93cf4f758ba9dee8a6cb2 232 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 14 213 1.3E-60 T 29-03-2018 IPR014197 Sporulation protein YunB CWR56_RS03820 738583f507e93cf4f758ba9dee8a6cb2 232 PIRSF PIRSF021383 3 225 6.1E-52 T 29-03-2018 IPR014197 Sporulation protein YunB CWR56_RS03820 738583f507e93cf4f758ba9dee8a6cb2 232 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 122 209 6.8E-34 T 29-03-2018 IPR014197 Sporulation protein YunB CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 SUPERFAMILY SSF48008 75 209 2.41E-33 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 5.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 5.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 5.6E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 5.6E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 Gene3D G3DSA:1.20.120.530 72 217 3.4E-36 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 SMART SM00345 11 69 5.7E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 Gene3D G3DSA:1.10.10.10 2 71 9.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 69 8.8E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 Pfam PF07729 FCD domain 79 202 7.6E-31 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 SUPERFAMILY SSF46785 4 73 1.61E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17800 b14540debdfa57bc067e047a2c1e098a 218 SMART SM00895 79 203 7.8E-23 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 SUPERFAMILY SSF55604 7 82 3.01E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 SUPERFAMILY SSF51261 484 636 9.59E-54 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 491 615 5.3E-50 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 Pfam PF02378 Phosphotransferase system, EIIC 110 405 2.1E-25 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 492 612 9.7E-45 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 Gene3D G3DSA:2.70.70.10 480 638 1.2E-56 T 29-03-2018 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 636 5.0E-217 T 29-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 Gene3D G3DSA:3.30.1360.60 3 77 1.9E-28 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 Pfam PF00367 phosphotransferase system, EIIB 9 42 7.6E-16 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15470 437cd78f0d2cfe504849baa02839dd0b 638 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 554 566 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS11500 4adaed2185b337e139f368fe74b63dd6 243 Pfam PF04016 Putative heavy-metal chelation 138 217 1.6E-8 T 29-03-2018 IPR007161 Putative heavy-metal chelation domain CWR56_RS11500 4adaed2185b337e139f368fe74b63dd6 243 SUPERFAMILY SSF159713 71 218 1.05E-18 T 29-03-2018 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 177 4.4E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 SUPERFAMILY SSF54980 403 498 1.39E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 303.612 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Pfam PF00009 Elongation factor Tu GTP binding domain 7 185 8.3E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 SUPERFAMILY SSF54980 296 374 4.68E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 PRINTS PR00315 GTP-binding elongation factor signature 10 23 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 PRINTS PR00315 GTP-binding elongation factor signature 130 139 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 PRINTS PR00315 GTP-binding elongation factor signature 53 61 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 SUPERFAMILY SSF50447 169 292 1.83E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Gene3D G3DSA:3.30.70.870 292 371 1.9E-27 T 29-03-2018 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 SUPERFAMILY SSF52540 4 209 2.28E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Gene3D G3DSA:3.30.70.240 394 553 1.9E-31 T 29-03-2018 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Pfam PF03144 Elongation factor Tu domain 2 209 279 1.8E-15 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 2.2E-50 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 TIGRFAM TIGR01393 lepA: elongation factor 4 7 600 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Gene3D G3DSA:3.40.50.300 3 189 6.2E-37 T 29-03-2018 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Gene3D G3DSA:2.40.30.10 192 291 8.8E-31 T 29-03-2018 CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 SMART SM00838 402 485 0.0011 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS12470 e9cb5268398de65e4b05a6c514752b3a 601 Pfam PF00679 Elongation factor G C-terminus 403 489 9.5E-24 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR56_RS18265 54ac7222ba86900239eef3a638d15f24 468 Gene3D G3DSA:1.10.390.10 314 465 2.2E-22 T 29-03-2018 CWR56_RS18265 54ac7222ba86900239eef3a638d15f24 468 Pfam PF01433 Peptidase family M1 domain 260 464 3.5E-20 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CWR56_RS18265 54ac7222ba86900239eef3a638d15f24 468 Gene3D G3DSA:2.60.40.1730 23 293 6.1E-12 T 29-03-2018 CWR56_RS18265 54ac7222ba86900239eef3a638d15f24 468 SUPERFAMILY SSF55486 263 453 1.9E-38 T 29-03-2018 CWR56_RS14305 62c6e967abd19cf6bca0f83746ddacaf 88 Pfam PF01872 RibD C-terminal domain 3 79 5.1E-12 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CWR56_RS14305 62c6e967abd19cf6bca0f83746ddacaf 88 Gene3D G3DSA:3.40.430.10 2 88 1.8E-15 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR56_RS14305 62c6e967abd19cf6bca0f83746ddacaf 88 SUPERFAMILY SSF53597 4 77 1.23E-13 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR56_RS01130 46369127b6ed8f5fe50dbae7c8852dca 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 180 5.5E-80 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CWR56_RS01130 46369127b6ed8f5fe50dbae7c8852dca 185 SUPERFAMILY SSF51182 5 182 2.49E-73 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS01130 46369127b6ed8f5fe50dbae7c8852dca 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 180 4.2E-74 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CWR56_RS01130 46369127b6ed8f5fe50dbae7c8852dca 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 7 180 8.0E-70 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CWR56_RS01130 46369127b6ed8f5fe50dbae7c8852dca 185 Gene3D G3DSA:2.60.120.10 1 185 7.5E-76 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS02865 4c5a8074e830657bc35947542a2ff66c 445 Gene3D G3DSA:3.30.565.10 297 444 5.6E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02865 4c5a8074e830657bc35947542a2ff66c 445 Gene3D G3DSA:1.10.287.130 235 296 4.6E-11 T 29-03-2018 CWR56_RS02865 4c5a8074e830657bc35947542a2ff66c 445 Pfam PF14501 GHKL domain 339 442 1.4E-23 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS02865 4c5a8074e830657bc35947542a2ff66c 445 SUPERFAMILY SSF55874 304 438 3.72E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17990 2010b58a1dc6f891fd1bd98d62a1c058 244 Pfam PF01171 PP-loop family 26 204 1.1E-16 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CWR56_RS17990 2010b58a1dc6f891fd1bd98d62a1c058 244 Gene3D G3DSA:3.40.50.620 18 232 2.3E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS17990 2010b58a1dc6f891fd1bd98d62a1c058 244 PIRSF PIRSF004976 2 243 3.1E-67 T 29-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CWR56_RS17990 2010b58a1dc6f891fd1bd98d62a1c058 244 SUPERFAMILY SSF52402 3 216 4.63E-53 T 29-03-2018 CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 Gene3D G3DSA:3.40.630.10 1 316 6.3E-55 T 29-03-2018 CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 SUPERFAMILY SSF55031 211 298 2.24E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 Pfam PF07687 Peptidase dimerisation domain 207 315 3.8E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 SUPERFAMILY SSF53187 5 210 1.03E-56 T 29-03-2018 CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 SUPERFAMILY SSF53187 337 420 1.03E-56 T 29-03-2018 CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 Pfam PF01546 Peptidase family M20/M25/M40 105 419 1.4E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS01560 63ad8e4e0ee09dd2a5d5c61020a2d972 420 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 17 410 3.0E-89 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 6.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 SMART SM00345 14 72 1.5E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 SUPERFAMILY SSF46785 1 76 2.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 Gene3D G3DSA:3.40.1410.10 73 241 1.2E-39 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 Gene3D G3DSA:1.10.10.10 1 72 3.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 8.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 8.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 SMART SM00866 94 234 1.1E-38 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 Pfam PF07702 UTRA domain 95 233 8.6E-40 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS17210 66ac364eb08665a4fa8ddcd6941fa4df 241 SUPERFAMILY SSF64288 60 238 2.36E-50 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS01315 15e060d84735072cb56ea305412ce7dd 231 Gene3D G3DSA:3.30.1330.60 64 231 1.0E-38 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS01315 15e060d84735072cb56ea305412ce7dd 231 SUPERFAMILY SSF103088 106 228 5.76E-30 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS01315 15e060d84735072cb56ea305412ce7dd 231 Pfam PF00691 OmpA family 123 222 1.3E-20 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS01315 15e060d84735072cb56ea305412ce7dd 231 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 57 2.1E-18 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CWR56_RS06830 ef2edd417cfbcc8208b658561235ff40 168 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR56_RS06830 ef2edd417cfbcc8208b658561235ff40 168 Gene3D G3DSA:3.30.70.560 1 167 3.0E-60 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR56_RS06830 ef2edd417cfbcc8208b658561235ff40 168 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 132 2.3E-44 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR56_RS06830 ef2edd417cfbcc8208b658561235ff40 168 SUPERFAMILY SSF55083 1 151 1.7E-52 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR56_RS06830 ef2edd417cfbcc8208b658561235ff40 168 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 4.2E-39 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR56_RS04125 75091647c0c3ca3b6def83ecb7440870 284 SUPERFAMILY SSF81606 7 227 1.31E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS04125 75091647c0c3ca3b6def83ecb7440870 284 Gene3D G3DSA:3.60.40.10 6 277 0.0012 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS06635 56db8af19ef66e0c577277fc30c52bbd 222 Pfam PF01902 Diphthamide synthase 13 222 5.8E-42 T 29-03-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CWR56_RS06635 56db8af19ef66e0c577277fc30c52bbd 222 SUPERFAMILY SSF52402 10 221 4.63E-63 T 29-03-2018 CWR56_RS06635 56db8af19ef66e0c577277fc30c52bbd 222 Gene3D G3DSA:3.40.50.620 6 147 4.2E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS06635 56db8af19ef66e0c577277fc30c52bbd 222 Gene3D G3DSA:3.90.1490.10 149 222 6.4E-20 T 29-03-2018 CWR56_RS06635 56db8af19ef66e0c577277fc30c52bbd 222 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 11 222 2.6E-40 T 29-03-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CWR56_RS13815 cf9237eb7c501adbd141cab925fffd94 365 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 14 177 1.4E-32 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CWR56_RS13815 cf9237eb7c501adbd141cab925fffd94 365 Gene3D G3DSA:3.40.50.2000 193 339 7.0E-14 T 29-03-2018 CWR56_RS13815 cf9237eb7c501adbd141cab925fffd94 365 SUPERFAMILY SSF53756 1 348 2.63E-27 T 29-03-2018 CWR56_RS13815 cf9237eb7c501adbd141cab925fffd94 365 Gene3D G3DSA:3.40.50.2000 48 192 4.8E-5 T 29-03-2018 CWR56_RS13815 cf9237eb7c501adbd141cab925fffd94 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 195 336 2.7E-8 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 Pfam PF02780 Transketolase, C-terminal domain 180 300 4.9E-37 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 Gene3D G3DSA:3.40.50.920 180 313 1.2E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 Gene3D G3DSA:3.40.50.970 1 179 1.1E-51 T 29-03-2018 CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 SUPERFAMILY SSF52518 2 171 5.35E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 SMART SM00861 4 169 2.0E-61 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 SUPERFAMILY SSF52922 174 308 5.5E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS17240 1dfb4397be0a79ec594bb4a5804332e1 313 Pfam PF02779 Transketolase, pyrimidine binding domain 3 168 4.7E-41 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 125 9.1E-13 T 29-03-2018 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 324 7.4E-34 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 SUPERFAMILY SSF118116 470 653 6.02E-52 T 29-03-2018 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 95 101 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 Pfam PF08676 MutL C terminal dimerisation domain 471 610 9.8E-38 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 3 651 25.107 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 SMART SM00853 471 611 2.4E-47 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 Gene3D G3DSA:3.30.565.10 3 207 7.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 5 307 1.0E-90 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 SUPERFAMILY SSF54211 192 324 1.25E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 Gene3D G3DSA:3.30.230.10 215 327 5.8E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 SUPERFAMILY SSF55874 5 216 2.1E-54 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09415 e7a2cf6188e4053822e3d68c97a29eba 655 SMART SM01340 210 324 3.8E-45 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS04135 1981094793af1bc6374d8bc3a3b05852 313 Pfam PF04122 Putative cell wall binding repeat 2 228 297 1.2E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04135 1981094793af1bc6374d8bc3a3b05852 313 Pfam PF04122 Putative cell wall binding repeat 2 34 117 3.5E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04135 1981094793af1bc6374d8bc3a3b05852 313 Pfam PF04122 Putative cell wall binding repeat 2 129 220 6.0E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS05435 a7b9288d592b6e4d8a4fbc3baeae1e95 322 Gene3D G3DSA:3.40.50.300 114 319 3.7E-8 T 29-03-2018 CWR56_RS05435 a7b9288d592b6e4d8a4fbc3baeae1e95 322 SUPERFAMILY SSF52540 69 280 3.04E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05435 a7b9288d592b6e4d8a4fbc3baeae1e95 322 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 31 312 4.0E-109 T 29-03-2018 IPR014217 Sporulation stage III, protein AA CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 4 456 1.3E-153 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 Gene3D G3DSA:3.40.50.300 1 46 1.5E-8 T 29-03-2018 CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 Gene3D G3DSA:3.40.50.300 51 191 1.9E-23 T 29-03-2018 CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 SUPERFAMILY SSF52540 1 194 3.39E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 186 1.7E-17 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 Gene3D G3DSA:3.40.50.880 252 457 1.1E-20 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 SUPERFAMILY SSF52317 250 453 6.45E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 446 43.11 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CWR56_RS17110 c4aa09e0be5557ee469c3f2a156d8d16 458 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 254 444 1.1E-41 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CWR56_RS03895 5e7ca72514e34dbce36eaa2db908382c 298 SUPERFAMILY SSF51569 1 288 4.4E-68 T 29-03-2018 CWR56_RS03895 5e7ca72514e34dbce36eaa2db908382c 298 Gene3D G3DSA:3.20.20.70 1 291 4.0E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS03895 5e7ca72514e34dbce36eaa2db908382c 298 Pfam PF00682 HMGL-like 3 274 2.3E-50 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 418 435 7.7E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 455 7.7E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Pfam PF02954 Bacterial regulatory protein, Fis family 413 452 1.5E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 SUPERFAMILY SSF55785 7 107 2.27E-11 T 29-03-2018 IPR000014 PAS domain CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Pfam PF00158 Sigma-54 interaction domain 146 314 1.5E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Gene3D G3DSA:3.30.450.20 2 111 2.1E-9 T 29-03-2018 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Gene3D G3DSA:1.10.8.60 319 395 3.1E-19 T 29-03-2018 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 104 4.7E-8 T 29-03-2018 IPR000014 PAS domain CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Gene3D G3DSA:3.40.50.300 133 318 5.0E-22 T 29-03-2018 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 SUPERFAMILY SSF52540 148 388 4.85E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Pfam PF13426 PAS domain 18 106 2.9E-7 T 29-03-2018 IPR000014 PAS domain CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 SMART SM00382 166 310 9.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 Gene3D G3DSA:1.10.10.60 396 456 2.3E-14 T 29-03-2018 CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 SMART SM00091 8 74 2.4E-5 T 29-03-2018 IPR000014 PAS domain CWR56_RS03940 b951d94d632c537d9d92ed5ba7b86d46 458 SUPERFAMILY SSF46689 400 455 8.06E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 PIRSF PIRSF006485 4 441 1.7E-174 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Gene3D G3DSA:3.30.300.20 371 437 1.4E-33 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Gene3D G3DSA:1.20.120.430 72 245 2.4E-45 T 29-03-2018 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Gene3D G3DSA:1.20.120.430 1 71 1.5E-17 T 29-03-2018 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 356 436 5.5E-33 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 SUPERFAMILY SSF52540 7 170 3.31E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 3.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 76 94 3.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Hamap MF_00195 GTPase Der [der]. 5 439 40.451 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 6 436 1.3E-174 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Pfam PF01926 50S ribosome-binding GTPase 180 298 9.9E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Pfam PF01926 50S ribosome-binding GTPase 8 123 1.1E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 SUPERFAMILY SSF52540 141 439 4.05E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 178 347 3.9E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 155 1.5E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS13320 c8536318a88d3ed17ff36e726190885f 441 Gene3D G3DSA:1.20.120.430 246 370 2.7E-16 T 29-03-2018 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 Gene3D G3DSA:3.30.70.940 6 115 4.3E-41 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 SMART SM00738 6 115 5.3E-44 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 180 1.0E-52 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 SMART SM00739 126 153 2.6E-6 T 29-03-2018 IPR005824 KOW CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 Pfam PF02357 Transcription termination factor nusG 8 111 8.8E-28 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 180 23.359 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 PRINTS PR00338 Transcription termination factor NUSG signature 62 74 1.6E-10 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 PRINTS PR00338 Transcription termination factor NUSG signature 156 172 1.6E-10 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 PRINTS PR00338 Transcription termination factor NUSG signature 138 153 1.6E-10 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 Gene3D G3DSA:2.30.30.30 122 180 2.2E-14 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 SUPERFAMILY SSF50104 124 180 3.87E-13 T 29-03-2018 IPR008991 Translation protein SH3-like domain CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 SUPERFAMILY SSF82679 7 111 1.31E-37 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR56_RS00020 c78e0c2071c476e863c31748a2c3c15d 180 Pfam PF00467 KOW motif 130 159 4.1E-6 T 29-03-2018 IPR005824 KOW CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 SUPERFAMILY SSF53187 303 391 4.44E-74 T 29-03-2018 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 SUPERFAMILY SSF53187 7 202 4.44E-74 T 29-03-2018 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 381 2.1E-104 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 Gene3D G3DSA:3.40.630.10 4 189 9.9E-26 T 29-03-2018 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 Gene3D G3DSA:3.30.70.360 190 300 1.5E-25 T 29-03-2018 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 PIRSF PIRSF005962 3 392 1.6E-123 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 SUPERFAMILY SSF55031 190 301 1.23E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 Pfam PF01546 Peptidase family M20/M25/M40 76 382 3.2E-29 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS06535 867a582bdf5b739bc7461105ea2a23b1 392 Pfam PF07687 Peptidase dimerisation domain 191 282 3.4E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS00245 2353efe5e036e59f079a23e174bc9cef 288 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS00245 2353efe5e036e59f079a23e174bc9cef 288 SMART SM00382 32 224 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00245 2353efe5e036e59f079a23e174bc9cef 288 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 279 2.9E-121 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CWR56_RS00245 2353efe5e036e59f079a23e174bc9cef 288 Pfam PF00005 ABC transporter 23 173 9.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00245 2353efe5e036e59f079a23e174bc9cef 288 Gene3D G3DSA:3.40.50.300 1 245 7.0E-69 T 29-03-2018 CWR56_RS00245 2353efe5e036e59f079a23e174bc9cef 288 SUPERFAMILY SSF52540 3 235 3.33E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 SMART SM00267 140 311 2.7E-50 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 SMART SM00448 7 120 5.5E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 148 310 1.8E-45 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 Pfam PF00072 Response regulator receiver domain 9 120 7.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 Pfam PF00990 Diguanylate cyclase, GGDEF domain 153 306 5.4E-41 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 SUPERFAMILY SSF52172 5 140 4.55E-37 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 Gene3D G3DSA:3.40.50.2300 1 145 3.7E-32 T 29-03-2018 CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 SUPERFAMILY SSF55073 156 310 1.02E-42 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS02465 01b6989090e8574ec4d30b000cca119a 319 Gene3D G3DSA:3.30.70.270 146 318 1.0E-44 T 29-03-2018 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 550 1.6E-210 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 Pfam PF05746 DALR anticodon binding domain 582 678 3.3E-7 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 Gene3D G3DSA:1.10.730.10 574 685 3.7E-9 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 9.2E-35 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 9.2E-35 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 244 259 9.2E-35 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 9.2E-35 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 9.2E-35 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 686 1.4E-226 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 SUPERFAMILY SSF109604 336 490 5.13E-13 T 29-03-2018 CWR56_RS12280 6c432a5c637e2437c0dbf7661b1386b3 688 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 685 26.177 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS02810 03ed1e750ff9bb71b250e699a5beff5c 59 Pfam PF08241 Methyltransferase domain 3 53 3.5E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CWR56_RS02810 03ed1e750ff9bb71b250e699a5beff5c 59 SUPERFAMILY SSF53335 1 58 2.63E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS02810 03ed1e750ff9bb71b250e699a5beff5c 59 Gene3D G3DSA:3.40.50.150 1 59 3.3E-6 T 29-03-2018 CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 Gene3D G3DSA:3.10.580.10 1 78 2.6E-17 T 29-03-2018 CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 Gene3D G3DSA:3.10.580.10 82 153 3.5E-15 T 29-03-2018 CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 SMART SM00116 13 61 1.9E-12 T 29-03-2018 IPR000644 CBS domain CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 SMART SM00116 103 151 1.3E-10 T 29-03-2018 IPR000644 CBS domain CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 Pfam PF00571 CBS domain 6 59 5.0E-16 T 29-03-2018 IPR000644 CBS domain CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 Pfam PF00571 CBS domain 96 151 3.5E-16 T 29-03-2018 IPR000644 CBS domain CWR56_RS17270 f2724fce601caec205eb748fa5f22463 153 SUPERFAMILY SSF54631 1 152 2.28E-38 T 29-03-2018 CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 SMART SM00857 3 149 3.2E-58 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 Pfam PF13408 Recombinase zinc beta ribbon domain 313 376 1.1E-14 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 Pfam PF00239 Resolvase, N terminal domain 3 149 7.8E-39 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 SUPERFAMILY SSF53041 2 149 5.1E-38 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 Pfam PF07508 Recombinase 183 299 1.6E-19 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 Gene3D G3DSA:1.20.5.40 120 147 4.3E-9 T 29-03-2018 CWR56_RS09040 5c7b6ff887c1cfc3f12f969ea5e870f8 532 Gene3D G3DSA:3.40.50.1390 1 119 1.0E-37 T 29-03-2018 CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 Gene3D G3DSA:3.90.180.10 1 149 2.5E-44 T 29-03-2018 CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 Gene3D G3DSA:3.40.50.10730 150 288 6.7E-30 T 29-03-2018 CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 SUPERFAMILY SSF50129 2 171 1.52E-48 T 29-03-2018 IPR011032 GroES-like CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 SUPERFAMILY SSF51735 139 295 1.91E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 Pfam PF00107 Zinc-binding dehydrogenase 172 295 1.3E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 8.1E-31 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR56_RS02265 af1b6e1e2299af034b04904b3be02583 350 SMART SM00829 8 319 1.3E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR56_RS11050 aaecc5e2f1887bb5769cfd630d85bf06 334 Gene3D G3DSA:1.10.530.10 46 206 1.7E-14 T 29-03-2018 CWR56_RS11050 aaecc5e2f1887bb5769cfd630d85bf06 334 Pfam PF00877 NlpC/P60 family 226 331 2.4E-30 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS11050 aaecc5e2f1887bb5769cfd630d85bf06 334 Gene3D G3DSA:3.90.1720.10 207 334 5.7E-40 T 29-03-2018 CWR56_RS11050 aaecc5e2f1887bb5769cfd630d85bf06 334 Pfam PF13702 Lysozyme-like 48 203 1.6E-56 T 29-03-2018 CWR56_RS11050 aaecc5e2f1887bb5769cfd630d85bf06 334 SUPERFAMILY SSF53955 53 159 3.75E-11 T 29-03-2018 IPR023346 Lysozyme-like domain CWR56_RS11050 aaecc5e2f1887bb5769cfd630d85bf06 334 SUPERFAMILY SSF54001 206 333 5.89E-42 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Gene3D G3DSA:3.30.70.1430 555 651 1.6E-14 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82693 143 182 9.42E-14 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82693 268 322 9.42E-14 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82714 702 783 3.01E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.0E-46 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82866 290 489 4.97E-40 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Gene3D G3DSA:3.30.2090.10 181 269 2.7E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82693 40 134 1.96E-22 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Gene3D G3DSA:1.20.1640.10 281 503 3.7E-44 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Gene3D G3DSA:3.30.2090.10 698 786 3.2E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82866 782 1010 8.89E-48 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Gene3D G3DSA:3.30.70.1430 40 139 4.1E-23 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Gene3D G3DSA:1.20.1640.10 788 1008 1.7E-38 T 29-03-2018 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 Pfam PF00873 AcrB/AcrD/AcrF family 4 1005 3.3E-228 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82714 184 266 3.01E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR56_RS12150 716b8d33075b8c59ed97fc2052ff4d7e 1044 SUPERFAMILY SSF82693 554 651 1.73E-7 T 29-03-2018 CWR56_RS04400 d8a4b2a8b8f946878272785186031076 308 SUPERFAMILY SSF56281 66 306 5.11E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04400 d8a4b2a8b8f946878272785186031076 308 Pfam PF00753 Metallo-beta-lactamase superfamily 76 264 1.3E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04400 d8a4b2a8b8f946878272785186031076 308 Gene3D G3DSA:3.60.15.10 26 304 1.7E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04400 d8a4b2a8b8f946878272785186031076 308 SMART SM00849 76 268 4.7E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12120 4fbff53a33f4b9c9aff0d81904653715 190 Pfam PF05067 Manganese containing catalase 1 184 1.5E-50 T 29-03-2018 IPR007760 Manganese catalase CWR56_RS12120 4fbff53a33f4b9c9aff0d81904653715 190 SUPERFAMILY SSF47240 1 189 6.32E-63 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS12120 4fbff53a33f4b9c9aff0d81904653715 190 Gene3D G3DSA:1.20.1260.10 1 184 3.8E-44 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Pfam PF00578 AhpC/TSA family 11 139 2.4E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Gene3D G3DSA:3.20.20.80 223 703 8.6E-71 T 29-03-2018 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Gene3D G3DSA:3.30.1020.10 156 222 3.4E-23 T 29-03-2018 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 195 1.3E-8 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 SMART SM00636 381 682 8.4E-59 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 SUPERFAMILY SSF52833 9 213 2.0E-63 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Gene3D G3DSA:3.40.30.10 5 155 2.5E-37 T 29-03-2018 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Pfam PF00704 Glycosyl hydrolases family 18 394 682 5.8E-61 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 ProSitePatterns PS01095 Chitinases family 18 active site. 476 484 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 SUPERFAMILY SSF51445 654 685 3.33E-64 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 SUPERFAMILY SSF51445 390 606 3.33E-64 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS06735 b60e7998f2ee815a84124b57ad22f2ca 712 Hamap MF_00401 Peroxiredoxin. 8 215 42.241 T 29-03-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CWR56_RS14395 cf56f92ba14ca601456b145c16da9a92 500 Pfam PF03806 AbgT putative transporter family 3 498 2.3E-189 T 29-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 CWR56_RS06750 3921da2b1a10a60c9298ba4b9563fd6d 489 Pfam PF07501 G5 domain 380 441 2.7E-8 T 29-03-2018 IPR011098 G5 domain CWR56_RS06750 3921da2b1a10a60c9298ba4b9563fd6d 489 Pfam PF12229 Putative peptidoglycan binding domain 76 191 4.1E-24 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CWR56_RS06750 3921da2b1a10a60c9298ba4b9563fd6d 489 Pfam PF04294 VanW like protein 228 357 1.3E-50 T 29-03-2018 IPR007391 Vancomycin resistance VanW CWR56_RS06750 3921da2b1a10a60c9298ba4b9563fd6d 489 Gene3D G3DSA:2.20.230.10 375 447 2.1E-10 T 29-03-2018 CWR56_RS06750 3921da2b1a10a60c9298ba4b9563fd6d 489 SMART SM01208 367 442 9.2E-11 T 29-03-2018 IPR011098 G5 domain CWR56_RS10195 98786d2d56a3014d5b4eac70633cd52b 352 SUPERFAMILY SSF51412 4 342 4.43E-55 T 29-03-2018 CWR56_RS10195 98786d2d56a3014d5b4eac70633cd52b 352 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 208 228 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWR56_RS10195 98786d2d56a3014d5b4eac70633cd52b 352 Gene3D G3DSA:3.20.20.70 1 352 4.5E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10195 98786d2d56a3014d5b4eac70633cd52b 352 Pfam PF03060 Nitronate monooxygenase 11 350 4.5E-51 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CWR56_RS13165 12a36c23c89b9b9dedd91fafc06818ec 248 Pfam PF04397 LytTr DNA-binding domain 155 246 5.7E-16 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS13165 12a36c23c89b9b9dedd91fafc06818ec 248 SUPERFAMILY SSF52172 71 162 5.62E-5 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS13165 12a36c23c89b9b9dedd91fafc06818ec 248 SMART SM00850 153 247 5.5E-19 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS13165 12a36c23c89b9b9dedd91fafc06818ec 248 Gene3D G3DSA:2.40.50.40 147 213 2.4E-11 T 29-03-2018 CWR56_RS13165 12a36c23c89b9b9dedd91fafc06818ec 248 Gene3D G3DSA:3.40.50.2300 1 146 2.7E-5 T 29-03-2018 CWR56_RS13165 12a36c23c89b9b9dedd91fafc06818ec 248 Pfam PF00072 Response regulator receiver domain 17 116 1.8E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS18450 0408edb82620c605107129a465206b4d 68 SUPERFAMILY SSF55174 1 67 2.09E-19 T 29-03-2018 CWR56_RS18450 0408edb82620c605107129a465206b4d 68 Gene3D G3DSA:3.10.290.10 1 68 1.8E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS18450 0408edb82620c605107129a465206b4d 68 Pfam PF13275 S4 domain 4 67 2.7E-28 T 29-03-2018 CWR56_RS18450 0408edb82620c605107129a465206b4d 68 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 62 9.7E-26 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA CWR56_RS01170 b3b5546b2793645b5205600eb1eb6823 310 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 2.6E-14 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CWR56_RS01170 b3b5546b2793645b5205600eb1eb6823 310 SUPERFAMILY SSF64518 1 310 5.36E-50 T 29-03-2018 CWR56_RS01170 b3b5546b2793645b5205600eb1eb6823 310 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 155 2.1E-39 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CWR56_RS01170 b3b5546b2793645b5205600eb1eb6823 310 Gene3D G3DSA:1.20.1330.10 38 285 8.7E-22 T 29-03-2018 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 SMART SM00936 293 381 3.9E-12 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 Gene3D G3DSA:3.40.710.10 23 304 1.5E-47 T 29-03-2018 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 SUPERFAMILY SSF69189 285 366 2.94E-5 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 153 2.0E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 2.0E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 130 2.0E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 27 272 5.4E-57 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 293 377 8.4E-7 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 SUPERFAMILY SSF56601 6 293 1.98E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS02355 a7a6bedc6ec1e5aa603e8f8e54d8653c 409 Gene3D G3DSA:2.60.410.10 305 380 3.1E-9 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS02910 e9f8c18d1f7b3060e83e0970c9fe0fdb 145 Gene3D G3DSA:2.20.25.10 108 144 3.8E-7 T 29-03-2018 CWR56_RS02910 e9f8c18d1f7b3060e83e0970c9fe0fdb 145 SMART SM00850 47 144 2.1E-26 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS02910 e9f8c18d1f7b3060e83e0970c9fe0fdb 145 Gene3D G3DSA:2.40.50.40 40 107 2.9E-13 T 29-03-2018 CWR56_RS02910 e9f8c18d1f7b3060e83e0970c9fe0fdb 145 Pfam PF04397 LytTr DNA-binding domain 48 143 3.3E-21 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 SUPERFAMILY SSF51338 3 59 1.95E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 SUPERFAMILY SSF51338 352 387 1.95E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 PIRSF PIRSF038971 13 385 4.8E-96 T 29-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 Gene3D G3DSA:3.20.20.140 65 300 4.2E-6 T 29-03-2018 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 SUPERFAMILY SSF51556 224 349 1.41E-12 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 SUPERFAMILY SSF51556 60 188 1.41E-12 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 Gene3D G3DSA:2.30.40.10 301 388 2.1E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 Gene3D G3DSA:2.30.40.10 2 64 6.9E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17610 e9461bdbdd1206cbf2e00f5a8c29114e 389 Pfam PF01979 Amidohydrolase family 301 384 3.6E-10 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 Gene3D G3DSA:3.80.30.20 139 375 1.4E-50 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 Pfam PF00919 Uncharacterized protein family UPF0004 3 98 1.2E-28 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 6 429 1.4E-109 T 29-03-2018 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 419 9.0E-146 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 146 166 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 SMART SM00729 142 357 8.8E-57 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 7.4E-143 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 Pfam PF04055 Radical SAM superfamily 147 319 1.7E-28 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS12370 4439a76775397cb3ae25cbaaa30ba450 432 SUPERFAMILY SSF102114 121 362 3.66E-58 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Gene3D G3DSA:3.30.190.20 128 246 2.0E-41 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Pfam PF00005 ABC transporter 624 860 1.2E-11 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Gene3D G3DSA:3.40.50.300 397 606 1.9E-27 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Gene3D G3DSA:1.10.8.280 283 396 9.9E-38 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Gene3D G3DSA:3.40.50.300 36 98 0.0015 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Gene3D G3DSA:3.40.50.300 610 941 8.0E-60 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 SUPERFAMILY SSF52540 621 914 4.66E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Gene3D G3DSA:3.40.50.300 3 35 9.5E-4 T 29-03-2018 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 23.123 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 SUPERFAMILY SSF52540 9 205 4.95E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 SUPERFAMILY SSF52540 432 571 4.95E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16980 75471151f8ac196deef76986983d34a5 941 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 924 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWR56_RS03025 a753a7b4bb130c95d7f68c81697b130a 72 SUPERFAMILY SSF47413 5 70 5.36E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS03025 a753a7b4bb130c95d7f68c81697b130a 72 Gene3D G3DSA:1.10.3100.10 2 72 6.7E-18 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS03025 a753a7b4bb130c95d7f68c81697b130a 72 SMART SM00530 8 63 6.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS03025 a753a7b4bb130c95d7f68c81697b130a 72 Pfam PF01381 Helix-turn-helix 9 63 3.1E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS05055 cbe8427a7e7275ee603d28c98318f547 790 Pfam PF01228 Glycine radical 668 771 6.3E-30 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CWR56_RS05055 cbe8427a7e7275ee603d28c98318f547 790 Gene3D G3DSA:3.20.70.20 3 789 4.6E-285 T 29-03-2018 CWR56_RS05055 cbe8427a7e7275ee603d28c98318f547 790 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 4 787 2.0E-218 T 29-03-2018 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWR56_RS05055 cbe8427a7e7275ee603d28c98318f547 790 SUPERFAMILY SSF51998 3 788 8.85E-236 T 29-03-2018 CWR56_RS05055 cbe8427a7e7275ee603d28c98318f547 790 Pfam PF02901 Pyruvate formate lyase-like 4 651 1.2E-228 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 SUPERFAMILY SSF46689 9 56 1.25E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 SUPERFAMILY SSF55729 135 272 2.57E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 Gene3D G3DSA:3.40.630.30 134 273 7.8E-5 T 29-03-2018 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 Gene3D G3DSA:1.10.10.60 6 62 2.1E-12 T 29-03-2018 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 Gene3D G3DSA:1.10.10.60 63 110 5.5E-11 T 29-03-2018 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 SUPERFAMILY SSF46689 59 109 2.64E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 SMART SM00342 22 105 1.8E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 74 89 7.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 89 105 7.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS02085 3bf098800c5dc30f46baf0c10b290f3c 278 Pfam PF12833 Helix-turn-helix domain 28 106 2.5E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 451 1130 3.8E-237 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 SUPERFAMILY SSF52540 820 1119 3.0E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Gene3D G3DSA:3.40.50.300 815 1141 9.7E-47 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Gene3D G3DSA:3.40.50.300 360 388 0.0081 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Gene3D G3DSA:3.40.50.300 698 808 0.094 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 SUPERFAMILY SSF52540 328 432 4.65E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Pfam PF01841 Transglutaminase-like superfamily 57 150 2.0E-5 T 29-03-2018 IPR002931 Transglutaminase-like CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 ProSitePatterns PS00211 ABC transporters family signature. 697 711 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 SUPERFAMILY SSF54001 48 174 1.4E-14 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Pfam PF00005 ABC transporter 830 1066 6.1E-8 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Gene3D G3DSA:3.40.50.300 234 349 0.11 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Gene3D G3DSA:3.40.50.300 350 359 0.2 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 Gene3D G3DSA:1.20.1580.10 412 697 1.1E-55 T 29-03-2018 CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 SUPERFAMILY SSF52540 326 363 5.27E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 SUPERFAMILY SSF52540 552 798 5.27E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01015 d8540b899900a34954b61a090712a809 1142 ProSitePatterns PS00211 ABC transporters family signature. 1036 1050 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 SMART SM00729 184 402 1.5E-58 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 Pfam PF00919 Uncharacterized protein family UPF0004 41 141 3.3E-28 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 Pfam PF04055 Radical SAM superfamily 188 359 8.9E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 42 476 7.5E-165 T 29-03-2018 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 39 477 71.774 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 Pfam PF01938 TRAM domain 418 476 3.0E-12 T 29-03-2018 IPR002792 TRAM domain CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 Gene3D G3DSA:3.80.30.20 183 416 1.6E-56 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 188 208 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 42 473 4.6E-149 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CWR56_RS09470 51b4f70e2cabc5f0e35705749099bfd3 478 SUPERFAMILY SSF102114 179 456 1.09E-59 T 29-03-2018 CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 258 7.9E-13 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 Gene3D G3DSA:3.40.50.80 107 212 7.4E-13 T 29-03-2018 CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 Pfam PF00175 Oxidoreductase NAD-binding domain 111 206 5.9E-6 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 SUPERFAMILY SSF63380 4 92 2.34E-19 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 Gene3D G3DSA:2.40.30.10 1 92 3.8E-10 T 29-03-2018 CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 SUPERFAMILY SSF52343 100 257 1.15E-33 T 29-03-2018 CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 Gene3D G3DSA:2.10.240.10 222 258 2.3E-9 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWR56_RS07275 02ff01598b14c2448629bb0d7ee02040 297 PIRSF PIRSF006816 1 264 1.5E-65 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CWR56_RS15290 07497a591b7019e02f44172a2abc09be 134 SUPERFAMILY SSF53062 3 124 2.75E-30 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS15290 07497a591b7019e02f44172a2abc09be 134 Gene3D G3DSA:3.40.50.510 2 134 1.9E-28 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS15290 07497a591b7019e02f44172a2abc09be 134 Pfam PF03610 PTS system fructose IIA component 4 106 5.6E-23 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 Pfam PF08447 PAS fold 53 124 2.6E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 SUPERFAMILY SSF55785 22 130 2.27E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 Gene3D G3DSA:3.30.450.20 17 130 1.5E-9 T 29-03-2018 CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 Gene3D G3DSA:3.30.70.270 131 297 2.3E-42 T 29-03-2018 CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 Pfam PF00990 Diguanylate cyclase, GGDEF domain 134 287 7.3E-34 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 SUPERFAMILY SSF55073 139 293 5.41E-38 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 SMART SM00267 122 291 2.0E-26 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 SMART SM00052 301 548 1.1E-85 T 29-03-2018 IPR001633 EAL domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 Pfam PF00563 EAL domain 309 543 9.1E-63 T 29-03-2018 IPR001633 EAL domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 135 290 2.6E-28 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 Gene3D G3DSA:3.20.20.450 298 552 2.3E-82 T 29-03-2018 IPR001633 EAL domain CWR56_RS03675 dcdc74968fa09b585ff85fceef987306 556 SUPERFAMILY SSF141868 310 554 2.35E-80 T 29-03-2018 IPR001633 EAL domain CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 7 417 8.3E-83 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 Gene3D G3DSA:1.20.1250.20 1 192 1.1E-37 T 29-03-2018 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 Pfam PF07690 Major Facilitator Superfamily 11 397 1.2E-61 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 SUPERFAMILY SSF103473 2 190 2.75E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 SUPERFAMILY SSF103473 236 451 2.75E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 Gene3D G3DSA:1.20.1250.20 247 455 9.6E-36 T 29-03-2018 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 255 280 5.3E-12 T 29-03-2018 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 5.3E-12 T 29-03-2018 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 5.3E-12 T 29-03-2018 CWR56_RS16590 2324d76c4f59219df5534e0f29247e2e 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 5.3E-12 T 29-03-2018 CWR56_RS11665 668d6069a9674715edaab32809e04247 359 SUPERFAMILY SSF53092 3 131 1.88E-19 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS11665 668d6069a9674715edaab32809e04247 359 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 133 6.6E-25 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR56_RS11665 668d6069a9674715edaab32809e04247 359 Gene3D G3DSA:3.90.230.10 117 359 9.8E-79 T 29-03-2018 CWR56_RS11665 668d6069a9674715edaab32809e04247 359 Pfam PF00557 Metallopeptidase family M24 142 341 5.6E-62 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS11665 668d6069a9674715edaab32809e04247 359 Gene3D G3DSA:3.40.350.10 1 116 4.5E-22 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS11665 668d6069a9674715edaab32809e04247 359 SUPERFAMILY SSF55920 88 352 1.31E-75 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS05770 1f494e928fdc4e9eba6cfb68c0193ae0 356 Pfam PF16199 Radical_SAM C-terminal domain 183 268 1.8E-20 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CWR56_RS05770 1f494e928fdc4e9eba6cfb68c0193ae0 356 Gene3D G3DSA:3.20.20.70 3 323 8.5E-33 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS05770 1f494e928fdc4e9eba6cfb68c0193ae0 356 SUPERFAMILY SSF102114 8 263 6.67E-50 T 29-03-2018 CWR56_RS05770 1f494e928fdc4e9eba6cfb68c0193ae0 356 Pfam PF04055 Radical SAM superfamily 10 170 3.0E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS05770 1f494e928fdc4e9eba6cfb68c0193ae0 356 SMART SM00729 5 222 1.3E-35 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Gene3D G3DSA:2.40.30.10 303 396 7.1E-31 T 29-03-2018 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 PRINTS PR00315 GTP-binding elongation factor signature 132 141 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 SUPERFAMILY SSF50447 207 302 1.28E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 2.9E-32 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Gene3D G3DSA:2.40.30.10 195 300 2.1E-30 T 29-03-2018 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 SUPERFAMILY SSF50465 305 397 6.91E-34 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 2.7E-221 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.5E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.007 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 7.1E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.4E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 Gene3D G3DSA:3.40.50.300 1 194 2.4E-43 T 29-03-2018 CWR56_RS00075 22218e6534a48b46aa0320a7145132f6 397 SUPERFAMILY SSF52540 6 221 9.06E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 Gene3D G3DSA:3.40.50.2300 166 327 7.9E-36 T 29-03-2018 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 Gene3D G3DSA:1.10.10.10 1 18 9.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 Gene3D G3DSA:3.40.50.2300 59 165 3.3E-20 T 29-03-2018 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 29-03-2018 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 SUPERFAMILY SSF53822 59 310 3.34E-55 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 Gene3D G3DSA:1.10.260.40 19 58 4.9E-21 T 29-03-2018 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 SMART SM00354 3 72 4.4E-29 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 SUPERFAMILY SSF47413 1 60 8.45E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 1.9E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 1.9E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 64 308 2.4E-24 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CWR56_RS08690 e2ce314d17aa038ef8fba879e4751aeb 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 2.5E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS07320 7a4f0a9977565b9c4df476e399ec9e09 188 Gene3D G3DSA:1.10.1660.10 52 179 1.6E-4 T 29-03-2018 CWR56_RS07320 7a4f0a9977565b9c4df476e399ec9e09 188 Pfam PF08876 Domain of unknown function (DUF1836) 21 124 7.2E-32 T 29-03-2018 IPR014975 Protein of unknown function DUF1836 CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 SUPERFAMILY SSF55073 490 638 2.75E-19 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 Pfam PF00563 EAL domain 653 887 4.6E-56 T 29-03-2018 IPR001633 EAL domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 SMART SM00052 646 892 5.1E-62 T 29-03-2018 IPR001633 EAL domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 Pfam PF00990 Diguanylate cyclase, GGDEF domain 490 629 9.5E-13 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 Pfam PF00990 Diguanylate cyclase, GGDEF domain 289 423 2.0E-8 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 SUPERFAMILY SSF141868 652 898 1.7E-65 T 29-03-2018 IPR001633 EAL domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 Gene3D G3DSA:3.30.70.270 276 429 4.8E-14 T 29-03-2018 CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 SMART SM00267 471 636 2.5E-6 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 Gene3D G3DSA:3.20.20.450 643 895 5.1E-72 T 29-03-2018 IPR001633 EAL domain CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 SUPERFAMILY SSF55073 289 423 9.42E-11 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS13965 6582f5347e1cbea1cdbe78d2eacd384d 900 Gene3D G3DSA:3.30.70.270 476 642 2.3E-22 T 29-03-2018 CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 Gene3D G3DSA:3.40.50.200 68 556 7.3E-52 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 Pfam PF00082 Subtilase family 426 542 3.4E-10 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 Pfam PF00082 Subtilase family 96 283 5.4E-12 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 SUPERFAMILY SSF52743 90 280 5.86E-45 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 SUPERFAMILY SSF52743 420 553 5.86E-45 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 96 115 2.0E-11 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 2.0E-11 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 482 498 2.0E-11 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS10875 63919b2c10f02cde745c368e98f585cd 557 PIRSF PIRSF037894 2 555 1.2E-110 T 29-03-2018 IPR017310 Peptidase S8A, subtilisin-related, clostridia CWR56_RS17305 bb83b8cd9c43e237d8ae9345904a5259 165 Gene3D G3DSA:1.20.5.620 53 127 4.7E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CWR56_RS17305 bb83b8cd9c43e237d8ae9345904a5259 165 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 16 161 8.5E-29 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CWR56_RS17305 bb83b8cd9c43e237d8ae9345904a5259 165 Hamap MF_01398 ATP synthase subunit b [atpF]. 7 143 12.219 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWR56_RS17305 bb83b8cd9c43e237d8ae9345904a5259 165 Pfam PF00430 ATP synthase B/B' CF(0) 12 142 7.3E-27 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWR56_RS17305 bb83b8cd9c43e237d8ae9345904a5259 165 SUPERFAMILY SSF81573 71 126 5.89E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CWR56_RS12300 b8b7a10f2aa71dfd8bb230bf13df1f6c 51 Pfam PF14006 YqzL-like protein 3 40 6.5E-9 T 29-03-2018 IPR025617 YqzL-like protein CWR56_RS04380 d5b371709a846e4e0fe7458c234a733f 292 Gene3D G3DSA:3.40.800.10 14 292 5.1E-81 T 29-03-2018 CWR56_RS04380 d5b371709a846e4e0fe7458c234a733f 292 SUPERFAMILY SSF52768 6 286 6.3E-80 T 29-03-2018 CWR56_RS04380 d5b371709a846e4e0fe7458c234a733f 292 PIRSF PIRSF036979 1 291 2.5E-91 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CWR56_RS04380 d5b371709a846e4e0fe7458c234a733f 292 TIGRFAM TIGR01230 agmatinase: agmatinase 10 285 7.5E-82 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CWR56_RS04380 d5b371709a846e4e0fe7458c234a733f 292 Pfam PF00491 Arginase family 22 283 3.6E-77 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CWR56_RS04380 d5b371709a846e4e0fe7458c234a733f 292 ProSitePatterns PS01053 Arginase family signature. 213 234 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 Gene3D G3DSA:3.40.630.40 477 673 2.4E-50 T 29-03-2018 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 Pfam PF04122 Putative cell wall binding repeat 2 377 457 2.0E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 Pfam PF04122 Putative cell wall binding repeat 2 172 257 3.7E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 Pfam PF04122 Putative cell wall binding repeat 2 272 361 3.3E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 SUPERFAMILY SSF53187 489 673 1.1E-47 T 29-03-2018 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 491 671 9.8E-49 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS14120 b6e5029423f77f7923c117cc00c9416b 675 SMART SM00646 552 675 8.1E-20 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 208 52.516 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 Gene3D G3DSA:3.40.190.10 2 124 8.6E-41 T 29-03-2018 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 183 2.6E-62 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 SUPERFAMILY SSF53850 3 204 5.72E-65 T 29-03-2018 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 Gene3D G3DSA:3.40.190.10 125 207 2.0E-22 T 29-03-2018 CWR56_RS07340 a946de9de28fc2c73860acdfa4543ccc 208 Pfam PF01634 ATP phosphoribosyltransferase 52 203 2.0E-54 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CWR56_RS04325 06c722cae7ec1ae9f5ff622cb4a41562 148 SUPERFAMILY SSF141322 70 140 1.09E-11 T 29-03-2018 CWR56_RS04325 06c722cae7ec1ae9f5ff622cb4a41562 148 Pfam PF01957 NfeD-like C-terminal, partner-binding 4 139 8.1E-19 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CWR56_RS04325 06c722cae7ec1ae9f5ff622cb4a41562 148 Gene3D G3DSA:2.40.50.140 63 142 4.4E-19 T 29-03-2018 CWR56_RS14655 f136e0c34acec169b140a206cb8e91db 103 SUPERFAMILY SSF52794 1 100 2.01E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS14655 f136e0c34acec169b140a206cb8e91db 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 3.3E-25 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS14655 f136e0c34acec169b140a206cb8e91db 103 Gene3D G3DSA:3.40.50.2300 2 103 7.7E-38 T 29-03-2018 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 SUPERFAMILY SSF55068 4 169 8.11E-73 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 Gene3D G3DSA:3.30.1060.10 1 171 9.9E-67 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 169 303 36.057 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 179 311 4.6E-61 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 Pfam PF01625 Peptide methionine sulfoxide reductase 7 157 2.1E-61 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 Gene3D G3DSA:2.170.150.20 172 319 2.2E-51 T 29-03-2018 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 4 163 36.848 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 156 2.8E-63 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 SUPERFAMILY SSF51316 178 318 2.77E-56 T 29-03-2018 IPR011057 Mss4-like CWR56_RS10445 733fb019c40ec69d3383f785b3c3bd42 319 Pfam PF01641 SelR domain 182 302 9.2E-47 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 PIRSF PIRSF000538 1 505 1.6E-169 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 TIGRFAM TIGR01312 XylB: xylulokinase 5 495 5.6E-178 T 29-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 247 1.9E-82 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 Gene3D G3DSA:3.30.420.40 1 244 3.4E-84 T 29-03-2018 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 452 2.1E-37 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 Gene3D G3DSA:3.30.420.40 245 501 5.3E-65 T 29-03-2018 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 SUPERFAMILY SSF53067 3 249 1.3E-85 T 29-03-2018 CWR56_RS15280 d0c0e8d5498152d65085b987a8af6b0b 514 SUPERFAMILY SSF53067 249 499 6.8E-68 T 29-03-2018 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 SMART SM00342 21 104 1.0E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 Gene3D G3DSA:3.20.80.10 114 289 2.0E-35 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 Gene3D G3DSA:1.10.10.60 5 61 4.7E-16 T 29-03-2018 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 SMART SM00871 132 289 2.4E-30 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 SUPERFAMILY SSF55136 134 289 3.49E-23 T 29-03-2018 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 Gene3D G3DSA:1.10.10.60 62 109 8.5E-10 T 29-03-2018 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 Pfam PF14526 Integron-associated effector binding protein 136 288 6.8E-30 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 SUPERFAMILY SSF46689 57 109 8.96E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 6.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 6.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 Pfam PF12833 Helix-turn-helix domain 27 105 2.7E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12210 8169cd60591c64b7947ee27b791c43c2 289 SUPERFAMILY SSF46689 5 55 2.82E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 SUPERFAMILY SSF53920 42 54 9.81E-127 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 SUPERFAMILY SSF53920 105 453 9.81E-127 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 107 389 1.7E-90 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 38 393 3.9E-129 T 29-03-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Gene3D G3DSA:4.10.260.20 401 459 7.3E-21 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Gene3D G3DSA:3.30.70.20 1 44 9.2E-12 T 29-03-2018 CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 SUPERFAMILY SSF54862 6 72 1.34E-16 T 29-03-2018 CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Pfam PF02256 Iron hydrogenase small subunit 404 453 4.0E-21 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Pfam PF13237 4Fe-4S dicluster domain 6 53 1.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 SMART SM00902 398 457 3.3E-21 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Gene3D G3DSA:3.40.50.1780 45 184 1.1E-22 T 29-03-2018 CWR56_RS16665 fa8027445f9e52c9019a2d4da334302c 461 Gene3D G3DSA:3.40.50.1780 185 312 8.9E-41 T 29-03-2018 CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 Gene3D G3DSA:3.40.1410.10 72 234 9.6E-32 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 5.7E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 SUPERFAMILY SSF64288 56 229 3.45E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 Pfam PF07702 UTRA domain 90 223 1.5E-29 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 SUPERFAMILY SSF46785 3 74 3.58E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 SMART SM00866 89 228 1.9E-29 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 Gene3D G3DSA:1.10.10.10 1 70 4.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14660 b34deb6a0d621cd9113326c555a9e1b7 234 SMART SM00345 9 68 3.3E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS15510 e5fdeb1192def10c1a547fb34f007002 383 Gene3D G3DSA:1.20.1090.10 190 361 2.5E-46 T 29-03-2018 CWR56_RS15510 e5fdeb1192def10c1a547fb34f007002 383 SUPERFAMILY SSF56796 2 381 3.27E-99 T 29-03-2018 CWR56_RS15510 e5fdeb1192def10c1a547fb34f007002 383 Gene3D G3DSA:3.40.50.1970 1 189 5.4E-44 T 29-03-2018 CWR56_RS15510 e5fdeb1192def10c1a547fb34f007002 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 359 4.7E-104 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS01930 c27c713a097422227bd5ff1a7ce6c44f 109 Gene3D G3DSA:3.30.429.10 2 108 1.3E-35 T 29-03-2018 CWR56_RS01930 c27c713a097422227bd5ff1a7ce6c44f 109 SUPERFAMILY SSF55331 1 109 1.19E-33 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CWR56_RS01930 c27c713a097422227bd5ff1a7ce6c44f 109 Pfam PF08921 Domain of unknown function (DUF1904) 1 108 1.9E-42 T 29-03-2018 IPR015017 Protein of unknown function DUF1904 CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 Gene3D G3DSA:3.30.1330.20 21 111 1.9E-28 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 Gene3D G3DSA:3.30.60.20 143 169 2.2E-10 T 29-03-2018 CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 SUPERFAMILY SSF143555 3 139 7.46E-44 T 29-03-2018 CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 14 104 2.2E-30 T 29-03-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 137 174 5.3E-9 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 PIRSF PIRSF006578 103 175 6.0E-18 T 29-03-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E CWR56_RS00845 cdd946965c18905e3f1b91ad4c789971 179 PIRSF PIRSF006578 2 113 1.8E-42 T 29-03-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 Pfam PF02195 ParB-like nuclease domain 34 121 1.4E-23 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 SUPERFAMILY SSF110849 27 126 4.71E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 29 207 2.6E-55 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 Gene3D G3DSA:1.10.10.730 123 170 1.5E-19 T 29-03-2018 CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 SUPERFAMILY SSF109709 114 224 1.65E-35 T 29-03-2018 CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 SMART SM00470 32 122 1.9E-25 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS18385 0cc46eebb22c93c3ec45b7ea2b12050b 287 Gene3D G3DSA:3.90.1530.10 20 122 4.3E-35 T 29-03-2018 CWR56_RS13950 463e76f9008130f1f082f840311395a8 192 Pfam PF04647 Accessory gene regulator B 6 182 2.4E-39 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR56_RS13950 463e76f9008130f1f082f840311395a8 192 SMART SM00793 4 175 7.6E-5 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 ProSitePatterns PS01135 FtsZ protein signature 2. 98 119 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 Pfam PF12327 FtsZ family, C-terminal domain 223 317 5.1E-35 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 SUPERFAMILY SSF55307 206 317 1.3E-42 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 SMART SM00864 14 206 2.0E-115 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 Gene3D G3DSA:3.30.1330.20 216 325 4.2E-45 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 PRINTS PR00423 Cell division protein FtsZ signature 99 119 8.1E-48 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 PRINTS PR00423 Cell division protein FtsZ signature 190 212 8.1E-48 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 PRINTS PR00423 Cell division protein FtsZ signature 127 148 8.1E-48 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 PRINTS PR00423 Cell division protein FtsZ signature 213 234 8.1E-48 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 SMART SM00865 208 325 3.2E-55 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 175 1.5E-44 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 323 1.0E-130 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 376 38.399 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 SUPERFAMILY SSF52490 13 209 3.01E-71 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CWR56_RS13390 4776ff0eb8074a84ad0e18f765a39165 386 Gene3D G3DSA:3.40.50.1440 7 215 2.8E-46 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 SUPERFAMILY SSF55174 14 102 8.58E-13 T 29-03-2018 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 Pfam PF01479 S4 domain 16 62 3.6E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 Gene3D G3DSA:3.10.290.10 2 73 4.2E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 Pfam PF00849 RNA pseudouridylate synthase 89 242 1.2E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 Gene3D G3DSA:3.30.2350.10 80 303 3.4E-69 T 29-03-2018 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 SMART SM00363 16 80 6.7E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 SUPERFAMILY SSF55120 74 301 2.26E-76 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS13130 0204030da722ba79ae042afe6e951800 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 302 1.8E-99 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS18420 b9669d7da1e94e19b0feb0be6333aff0 235 Pfam PF02096 60Kd inner membrane protein 22 209 2.0E-60 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR56_RS18420 b9669d7da1e94e19b0feb0be6333aff0 235 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 22 209 4.2E-62 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWR56_RS01465 119d529ccbaf206587296842c2007396 133 SUPERFAMILY SSF53062 4 119 1.7E-12 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01465 119d529ccbaf206587296842c2007396 133 Gene3D G3DSA:3.40.50.510 4 128 1.6E-11 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS05605 cffd9dd9418c344581c59a71f37dd7f2 359 Gene3D G3DSA:3.30.160.60 75 108 2.5E-6 T 29-03-2018 CWR56_RS05605 cffd9dd9418c344581c59a71f37dd7f2 359 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 11 340 34.216 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CWR56_RS05605 cffd9dd9418c344581c59a71f37dd7f2 359 Gene3D G3DSA:3.30.160.60 311 345 1.1E-10 T 29-03-2018 CWR56_RS05605 cffd9dd9418c344581c59a71f37dd7f2 359 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 11 339 2.9E-88 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CWR56_RS05605 cffd9dd9418c344581c59a71f37dd7f2 359 Pfam PF02618 YceG-like family 43 336 8.6E-82 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CWR56_RS07805 25bf4ba3c9335d69aa45115304af9c59 378 PIRSF PIRSF026508 9 376 1.4E-98 T 29-03-2018 IPR008863 Toxic anion resistance CWR56_RS07805 25bf4ba3c9335d69aa45115304af9c59 378 Pfam PF05816 Toxic anion resistance protein (TelA) 49 373 1.8E-101 T 29-03-2018 IPR008863 Toxic anion resistance CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Gene3D G3DSA:3.30.450.40 94 269 3.0E-14 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SUPERFAMILY SSF55073 619 770 2.12E-26 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Gene3D G3DSA:3.30.70.270 280 438 3.3E-29 T 29-03-2018 CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SUPERFAMILY SSF141868 783 1031 6.67E-78 T 29-03-2018 IPR001633 EAL domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SMART SM00267 279 438 4.6E-18 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SMART SM00267 604 768 7.3E-8 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SUPERFAMILY SSF55781 141 257 2.18E-7 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Gene3D G3DSA:3.30.70.270 611 776 1.0E-26 T 29-03-2018 CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SMART SM00052 778 1024 1.2E-83 T 29-03-2018 IPR001633 EAL domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 286 435 8.7E-21 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 614 726 6.5E-20 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Pfam PF00563 EAL domain 784 1019 7.0E-62 T 29-03-2018 IPR001633 EAL domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Gene3D G3DSA:3.20.20.450 777 1032 6.7E-80 T 29-03-2018 IPR001633 EAL domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 SUPERFAMILY SSF55073 295 434 7.69E-24 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Pfam PF00990 Diguanylate cyclase, GGDEF domain 291 432 4.5E-21 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02395 d3d015da2c35ce801accbdb46c0ca7b3 1032 Pfam PF00990 Diguanylate cyclase, GGDEF domain 616 723 1.1E-20 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08295 ebd13e0e859f0edf83b2557f7dd9b1e3 270 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 31 269 9.3E-91 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CWR56_RS08295 ebd13e0e859f0edf83b2557f7dd9b1e3 270 SUPERFAMILY SSF52540 24 252 2.03E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08295 ebd13e0e859f0edf83b2557f7dd9b1e3 270 ProSitePatterns PS01215 Mrp family signature. 137 153 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CWR56_RS08295 ebd13e0e859f0edf83b2557f7dd9b1e3 270 Gene3D G3DSA:3.40.50.300 13 251 1.7E-53 T 29-03-2018 CWR56_RS08295 ebd13e0e859f0edf83b2557f7dd9b1e3 270 Hamap MF_02040 Iron-sulfur cluster carrier protein. 24 270 34.265 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CWR56_RS09090 3e12d2e368889929463136eaaf15f043 217 PIRSF PIRSF012290 1 217 1.8E-88 T 29-03-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 CWR56_RS09090 3e12d2e368889929463136eaaf15f043 217 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 5 215 2.8E-111 T 29-03-2018 IPR030983 Ethanolamine utilization protein EutL GO:0005198 CWR56_RS09090 3e12d2e368889929463136eaaf15f043 217 SUPERFAMILY SSF143414 155 210 9.03E-6 T 29-03-2018 CWR56_RS09090 3e12d2e368889929463136eaaf15f043 217 Pfam PF00936 BMC domain 35 106 2.5E-11 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09090 3e12d2e368889929463136eaaf15f043 217 SMART SM00877 34 121 4.2E-5 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09090 3e12d2e368889929463136eaaf15f043 217 SMART SM00877 145 214 1.7E-9 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 Gene3D G3DSA:3.40.50.300 1 241 4.5E-71 T 29-03-2018 CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 SMART SM00382 29 212 3.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 Gene3D G3DSA:2.40.50.140 298 353 3.8E-12 T 29-03-2018 CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 Pfam PF00005 ABC transporter 20 162 1.5E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 SUPERFAMILY SSF52540 5 245 1.17E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 SUPERFAMILY SSF50331 238 368 1.99E-24 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 Gene3D G3DSA:2.40.50.100 242 297 3.9E-10 T 29-03-2018 CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 Pfam PF08402 TOBE domain 285 360 1.8E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CWR56_RS12410 2c780992869c204fe770eaa8550d866e 369 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 282 483 2.5E-32 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 260 1.6E-17 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Gene3D G3DSA:3.40.190.10 167 265 4.8E-10 T 29-03-2018 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Gene3D G3DSA:3.40.190.10 31 166 1.1E-11 T 29-03-2018 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 SMART SM00267 664 832 1.2E-44 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Gene3D G3DSA:3.40.190.10 266 390 3.9E-20 T 29-03-2018 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 674 830 3.0E-37 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Pfam PF00990 Diguanylate cyclase, GGDEF domain 675 828 7.9E-38 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Gene3D G3DSA:3.30.70.270 663 832 1.8E-41 T 29-03-2018 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 SUPERFAMILY SSF55073 680 830 2.51E-35 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 SUPERFAMILY SSF53850 36 260 4.68E-26 T 29-03-2018 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 Gene3D G3DSA:3.40.190.10 391 455 2.4E-5 T 29-03-2018 CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 SMART SM00062 281 489 3.9E-16 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 SMART SM00062 35 262 1.4E-12 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS03400 027f7ff955a0a9c513e5cfbaacfa3df3 832 SUPERFAMILY SSF53850 282 486 2.66E-34 T 29-03-2018 CWR56_RS18480 2776ba2e6767e037b03ea5ba8256614c 103 Pfam PF01740 STAS domain 18 99 9.8E-16 T 29-03-2018 IPR002645 STAS domain CWR56_RS18480 2776ba2e6767e037b03ea5ba8256614c 103 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 102 2.3E-24 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CWR56_RS18480 2776ba2e6767e037b03ea5ba8256614c 103 Gene3D G3DSA:3.30.750.24 2 102 1.5E-15 T 29-03-2018 IPR002645 STAS domain CWR56_RS18480 2776ba2e6767e037b03ea5ba8256614c 103 SUPERFAMILY SSF52091 6 101 3.34E-21 T 29-03-2018 IPR002645 STAS domain CWR56_RS17470 728de2019360d7271e1fe8ae713a9087 220 Pfam PF01478 Type IV leader peptidase family 65 170 1.3E-6 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CWR56_RS14350 10ec8b8b79a89bfb420da66addc739e7 148 SMART SM00347 28 128 8.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14350 10ec8b8b79a89bfb420da66addc739e7 148 SUPERFAMILY SSF46785 10 138 8.24E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14350 10ec8b8b79a89bfb420da66addc739e7 148 Pfam PF01047 MarR family 35 92 2.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14350 10ec8b8b79a89bfb420da66addc739e7 148 Gene3D G3DSA:1.10.10.10 18 127 8.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14350 10ec8b8b79a89bfb420da66addc739e7 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14350 10ec8b8b79a89bfb420da66addc739e7 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 SUPERFAMILY SSF55874 360 527 3.8E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 SUPERFAMILY SSF55781 129 284 6.17E-9 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 SMART SM00388 303 371 9.4E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 466 5.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 480 5.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 5.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 5.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 SMART SM00387 415 527 2.7E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Gene3D G3DSA:3.30.565.10 366 527 1.1E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 419 525 1.8E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Gene3D G3DSA:1.20.120.620 30 131 1.2E-23 T 29-03-2018 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Gene3D G3DSA:1.10.287.130 301 365 1.3E-12 T 29-03-2018 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 SUPERFAMILY SSF47384 297 372 6.28E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Pfam PF00512 His Kinase A (phospho-acceptor) domain 304 371 1.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Gene3D G3DSA:3.30.450.40 214 300 1.5E-7 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS02380 e5385debb4fb78b16a0805e5d93aec2d 535 Pfam PF13493 Domain of unknown function (DUF4118) 32 139 4.0E-29 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CWR56_RS09860 735972fa217657e01c750ef374c9ec94 188 Gene3D G3DSA:3.90.1720.10 6 186 2.7E-5 T 29-03-2018 CWR56_RS08810 6f691b39fd16e574ffaba7d09e388ceb 147 Pfam PF01047 MarR family 34 92 1.4E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS08810 6f691b39fd16e574ffaba7d09e388ceb 147 Gene3D G3DSA:1.10.10.10 3 139 4.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08810 6f691b39fd16e574ffaba7d09e388ceb 147 SUPERFAMILY SSF46785 4 139 6.72E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08810 6f691b39fd16e574ffaba7d09e388ceb 147 SMART SM00347 27 124 2.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS08810 6f691b39fd16e574ffaba7d09e388ceb 147 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWR56_RS10100 78e14de68572daa096ce9e98f5d6ac02 360 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 24 327 1.4E-20 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR56_RS10100 78e14de68572daa096ce9e98f5d6ac02 360 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 22 327 2.3E-46 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 SMART SM00836 451 566 6.1E-45 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 2.0E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 115 130 2.0E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 130 146 2.0E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 154 167 2.0E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 SUPERFAMILY SSF52374 109 445 4.69E-103 T 29-03-2018 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 566 3.5E-165 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Gene3D G3DSA:1.10.730.10 432 566 1.2E-42 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 SMART SM01016 2 85 4.0E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Hamap MF_00123 Arginine--tRNA ligase [argS]. 6 566 26.628 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Pfam PF00750 tRNA synthetases class I (R) 95 437 3.2E-101 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Pfam PF05746 DALR anticodon binding domain 451 566 8.8E-31 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 84 1.2E-17 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Gene3D G3DSA:3.30.1360.70 1 109 6.9E-28 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 SUPERFAMILY SSF47323 447 566 2.49E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 SUPERFAMILY SSF55190 9 106 5.23E-25 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 123 134 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS03420 720be7b4ff0117a42760a9902f71768e 566 Gene3D G3DSA:3.40.50.620 110 431 9.8E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 Gene3D G3DSA:3.30.565.10 132 324 1.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 325 9.3E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 SUPERFAMILY SSF55874 164 324 3.01E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 5.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 5.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 325 5.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 5.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS14860 b04929de96f75313cf70be6df566d40f 334 SMART SM00387 216 328 6.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Pfam PF06506 Propionate catabolism activator 49 189 2.0E-22 T 29-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Gene3D G3DSA:3.30.450.20 185 309 3.4E-13 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Gene3D G3DSA:3.40.50.10660 91 169 2.3E-14 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 414 429 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Gene3D G3DSA:3.40.50.300 320 499 2.0E-26 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Pfam PF00989 PAS fold 200 299 1.6E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 SUPERFAMILY SSF52540 331 564 2.86E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Gene3D G3DSA:1.10.10.60 624 661 1.7E-4 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 548 557 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Gene3D G3DSA:3.40.50.2300 1 90 1.6E-12 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Pfam PF00158 Sigma-54 interaction domain 330 494 5.3E-63 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 Gene3D G3DSA:1.10.8.60 500 623 2.7E-13 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 SUPERFAMILY SSF159800 3 188 1.7E-35 T 29-03-2018 CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 197 308 1.6E-7 T 29-03-2018 IPR000014 PAS domain CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 SUPERFAMILY SSF55785 196 300 1.52E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS12020 b527ec59388a01a48a714333ad9bb30d 663 SMART SM00382 347 491 2.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 Gene3D G3DSA:1.10.10.60 62 119 5.1E-10 T 29-03-2018 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 SMART SM00871 128 285 4.5E-28 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 SUPERFAMILY SSF55136 128 286 3.92E-25 T 29-03-2018 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 Pfam PF06445 GyrI-like small molecule binding domain 128 284 1.4E-20 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 Gene3D G3DSA:3.20.80.10 127 286 1.0E-39 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 SUPERFAMILY SSF46689 57 111 1.88E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 SMART SM00342 21 104 9.1E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 Pfam PF12833 Helix-turn-helix domain 28 105 7.2E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 Gene3D G3DSA:1.10.10.60 4 61 1.6E-8 T 29-03-2018 CWR56_RS05090 c47759ff4c4559b5d29a2d2aa62192af 288 SUPERFAMILY SSF46689 5 55 7.62E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 Gene3D G3DSA:3.90.1640.10 329 545 1.8E-44 T 29-03-2018 CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 Gene3D G3DSA:3.30.450.20 77 172 3.0E-4 T 29-03-2018 CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 Gene3D G3DSA:3.30.70.270 173 312 2.6E-4 T 29-03-2018 CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 PIRSF PIRSF026583 1 664 3.4E-209 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 Pfam PF01368 DHH family 351 506 3.0E-22 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 Pfam PF02272 DHHA1 domain 528 656 6.0E-15 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR56_RS18320 94e58da412ddc204685dda2b8c94fb9b 664 SUPERFAMILY SSF64182 350 648 1.96E-62 T 29-03-2018 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 450 9.8E-64 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 496 2.3E-232 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 3.3E-86 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 PIRSF PIRSF000538 3 501 4.7E-184 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 Gene3D G3DSA:3.30.420.40 249 504 1.7E-79 T 29-03-2018 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 SUPERFAMILY SSF53067 255 496 9.71E-86 T 29-03-2018 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 60.142 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 SUPERFAMILY SSF53067 4 255 1.55E-97 T 29-03-2018 CWR56_RS06455 d73f6f02fa2e05de7d7c82f71789f2a8 504 Gene3D G3DSA:3.30.420.40 1 248 5.1E-88 T 29-03-2018 CWR56_RS04970 024416f51e61d895230b803dafe3331c 247 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 30 183 4.0E-8 T 29-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family CWR56_RS04970 024416f51e61d895230b803dafe3331c 247 SUPERFAMILY SSF51366 6 242 2.0E-16 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS04970 024416f51e61d895230b803dafe3331c 247 Gene3D G3DSA:3.20.20.380 4 247 3.7E-17 T 29-03-2018 CWR56_RS04970 024416f51e61d895230b803dafe3331c 247 Pfam PF03437 BtpA family 13 241 7.8E-25 T 29-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family CWR56_RS04875 a82b4208fbf4f25e93001cb943e46963 300 Pfam PF00849 RNA pseudouridylate synthase 91 242 5.9E-36 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS04875 a82b4208fbf4f25e93001cb943e46963 300 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 300 1.2E-79 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS04875 a82b4208fbf4f25e93001cb943e46963 300 Gene3D G3DSA:3.30.2350.10 82 300 9.8E-73 T 29-03-2018 CWR56_RS04875 a82b4208fbf4f25e93001cb943e46963 300 Gene3D G3DSA:3.10.290.10 5 76 6.0E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS04875 a82b4208fbf4f25e93001cb943e46963 300 SUPERFAMILY SSF55120 76 299 6.3E-71 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS04875 a82b4208fbf4f25e93001cb943e46963 300 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 5.2E-44 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 SMART SM00878 336 442 4.5E-59 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 SUPERFAMILY SSF52440 2 113 7.91E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 Gene3D G3DSA:3.30.1490.20 124 209 7.1E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.1E-39 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 9.2E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 2 444 1.2E-206 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 Gene3D G3DSA:3.30.470.20 210 445 1.0E-99 T 29-03-2018 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 SUPERFAMILY SSF51246 331 444 1.15E-42 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 SUPERFAMILY SSF56059 83 352 9.93E-73 T 29-03-2018 CWR56_RS09220 050b687efadd9f18f448e0e259cb2774 453 Gene3D G3DSA:3.40.50.20 1 123 3.3E-49 T 29-03-2018 CWR56_RS09925 c7372cc77993d7db5a0673cc21661cf5 192 SUPERFAMILY SSF53448 5 188 2.93E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS09925 c7372cc77993d7db5a0673cc21661cf5 192 Pfam PF12804 MobA-like NTP transferase domain 7 162 5.3E-32 T 29-03-2018 IPR025877 MobA-like NTP transferase CWR56_RS09925 c7372cc77993d7db5a0673cc21661cf5 192 Gene3D G3DSA:3.90.550.10 3 190 5.1E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS09925 c7372cc77993d7db5a0673cc21661cf5 192 TIGRFAM TIGR03310 matur_MocA_YgfJ: molybdenum cofactor cytidylyltransferase 6 188 1.4E-69 T 29-03-2018 IPR017696 Molybdenum cofactor cytidylyltransferase KEGG: 00790+2.7.7.76|MetaCyc: PWY-6476 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 Gene3D G3DSA:3.20.20.70 3 485 3.7E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 SMART SM01240 8 489 2.1E-180 T 29-03-2018 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 309 321 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 SUPERFAMILY SSF51412 6 100 2.49E-101 T 29-03-2018 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 SUPERFAMILY SSF51412 231 493 2.49E-101 T 29-03-2018 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 PIRSF PIRSF000130 3 498 2.2E-139 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 Pfam PF00571 CBS domain 163 214 5.8E-4 T 29-03-2018 IPR000644 CBS domain CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 489 1.2E-112 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CWR56_RS11605 9fcff2adda34d8de41b45efdedeb3f78 499 SUPERFAMILY SSF54631 110 214 6.34E-22 T 29-03-2018 CWR56_RS06580 439d6adf8c60eba46953f7ec6d57a9dc 268 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 191 268 9.6E-18 T 29-03-2018 CWR56_RS06580 439d6adf8c60eba46953f7ec6d57a9dc 268 Gene3D G3DSA:3.30.1380.10 119 267 1.2E-20 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS06580 439d6adf8c60eba46953f7ec6d57a9dc 268 SUPERFAMILY SSF55166 117 267 1.41E-25 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 5 293 5.9E-102 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 PIRSF PIRSF000371 1 302 1.0E-98 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 SUPERFAMILY SSF102114 92 279 5.89E-17 T 29-03-2018 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 Pfam PF13353 4Fe-4S single cluster domain 15 201 2.2E-7 T 29-03-2018 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 Gene3D G3DSA:3.80.30.10 123 302 9.6E-39 T 29-03-2018 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 Pfam PF04055 Radical SAM superfamily 23 231 9.8E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 SUPERFAMILY SSF54862 5 137 2.73E-18 T 29-03-2018 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 Gene3D G3DSA:3.30.70.20 25 62 1.3E-5 T 29-03-2018 CWR56_RS16510 bd3a1b6c1bf83997e57e7db7b3e009d0 302 Gene3D G3DSA:3.30.70.20 63 122 4.0E-11 T 29-03-2018 CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 PRINTS PR00956 Flagellar motor switch protein FliN signature 77 90 4.5E-18 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 PRINTS PR00956 Flagellar motor switch protein FliN signature 90 105 4.5E-18 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 PRINTS PR00956 Flagellar motor switch protein FliN signature 61 77 4.5E-18 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 PRINTS PR00956 Flagellar motor switch protein FliN signature 44 60 4.5E-18 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 SUPERFAMILY SSF101801 41 118 1.2E-21 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 43 114 1.3E-22 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01390 0b155a9da2579976ae673d6abcb5e48a 124 Gene3D G3DSA:2.30.330.10 32 124 3.3E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS04095 b5ecab1449870dd4bee03de6590eb1ab 164 Gene3D G3DSA:3.40.630.30 1 163 3.8E-24 T 29-03-2018 CWR56_RS04095 b5ecab1449870dd4bee03de6590eb1ab 164 Pfam PF00583 Acetyltransferase (GNAT) family 34 142 9.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS04095 b5ecab1449870dd4bee03de6590eb1ab 164 SUPERFAMILY SSF55729 2 160 1.15E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS15885 7dc6783b316613ceee44a554e9264beb 204 Pfam PF08713 DNA alkylation repair enzyme 17 180 2.1E-12 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CWR56_RS15885 7dc6783b316613ceee44a554e9264beb 204 Gene3D G3DSA:1.20.1660.10 14 97 0.0016 T 29-03-2018 CWR56_RS15885 7dc6783b316613ceee44a554e9264beb 204 Gene3D G3DSA:1.25.40.290 100 204 7.8E-19 T 29-03-2018 CWR56_RS15885 7dc6783b316613ceee44a554e9264beb 204 SUPERFAMILY SSF48371 14 201 4.8E-35 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 PIRSF PIRSF000732 1 570 5.6E-227 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 SUPERFAMILY SSF52009 124 245 1.83E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 Gene3D G3DSA:1.10.274.10 24 132 6.2E-38 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 183 194 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 463 478 6.2E-28 T 29-03-2018 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 292 311 6.2E-28 T 29-03-2018 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 446 461 6.2E-28 T 29-03-2018 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 499 511 6.2E-28 T 29-03-2018 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 SUPERFAMILY SSF47831 24 142 3.14E-37 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 125 3.5E-33 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 Gene3D G3DSA:3.50.30.10 133 253 3.6E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 539 5.8E-123 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 565 7.3E-231 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 Gene3D G3DSA:3.20.20.60 254 570 2.0E-100 T 29-03-2018 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 224 1.1E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS13975 2fbf3989e18a433c205c4818b580d919 570 SUPERFAMILY SSF51621 249 548 1.23E-109 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR56_RS06615 f64b3e135178f40d7c2db7921e7e8f03 314 Pfam PF00892 EamA-like transporter family 154 288 5.0E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS06615 f64b3e135178f40d7c2db7921e7e8f03 314 Pfam PF00892 EamA-like transporter family 6 141 1.2E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS06615 f64b3e135178f40d7c2db7921e7e8f03 314 SUPERFAMILY SSF103481 42 145 2.35E-13 T 29-03-2018 CWR56_RS06615 f64b3e135178f40d7c2db7921e7e8f03 314 SUPERFAMILY SSF103481 189 288 3.14E-6 T 29-03-2018 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 Pfam PF01479 S4 domain 1 44 3.9E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 SUPERFAMILY SSF55120 56 235 4.11E-47 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 SMART SM00363 1 63 9.5E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 SUPERFAMILY SSF55174 1 57 4.51E-13 T 29-03-2018 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 Gene3D G3DSA:3.10.290.10 1 71 7.0E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 Gene3D G3DSA:3.30.2350.10 72 238 1.6E-47 T 29-03-2018 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 Pfam PF00849 RNA pseudouridylate synthase 63 197 3.1E-24 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 228 2.3E-49 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR56_RS09820 a269bbb98a39f7c91e3286fe81d8c759 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR56_RS11565 00e161c1b2bf467fc692d1cdd1948c5a 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 150 6.7E-36 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11565 00e161c1b2bf467fc692d1cdd1948c5a 152 SUPERFAMILY SSF55804 1 151 6.8E-39 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11565 00e161c1b2bf467fc692d1cdd1948c5a 152 Gene3D G3DSA:3.40.930.10 1 152 1.9E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 SUPERFAMILY SSF52540 456 580 2.05E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 SUPERFAMILY SSF52540 35 80 2.05E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Gene3D G3DSA:3.40.50.300 414 584 5.3E-31 T 29-03-2018 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 SMART SM00487 7 422 1.0E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Pfam PF02151 UvrB/uvrC motif 621 652 2.5E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Pfam PF04851 Type III restriction enzyme, res subunit 10 90 4.7E-12 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Hamap MF_00204 UvrABC system protein B [uvrB]. 1 653 44.051 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Gene3D G3DSA:4.10.860.10 585 656 1.2E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Pfam PF00271 Helicase conserved C-terminal domain 434 542 3.4E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Pfam PF12344 Ultra-violet resistance protein B 549 591 2.2E-22 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 SUPERFAMILY SSF52540 3 412 7.19E-140 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 650 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 SUPERFAMILY SSF46600 614 655 2.22E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 SMART SM00490 457 543 2.6E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS16985 35c74100661850a7256d216e40fdf3ad 656 Gene3D G3DSA:3.40.50.300 8 413 4.3E-35 T 29-03-2018 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 SUPERFAMILY SSF50129 1 94 3.67E-31 T 29-03-2018 IPR011032 GroES-like CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 Gene3D G3DSA:2.30.33.40 1 94 1.1E-35 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.9E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 Hamap MF_00580 10 kDa chaperonin [groS]. 2 94 24.708 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 PRINTS PR00297 10kDa chaperonin signature 3 18 1.3E-28 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.3E-28 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 PRINTS PR00297 10kDa chaperonin signature 25 46 1.3E-28 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.3E-28 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS00960 67db5b90409bd233fcbf8f048c976802 94 SMART SM00883 2 93 1.2E-47 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 322 3.0E-11 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF55666 145 235 3.53E-27 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Gene3D G3DSA:2.40.50.140 629 697 2.9E-24 T 29-03-2018 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 695 30.422 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF46915 240 323 1.91E-15 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF01138 3' exoribonuclease family, domain 1 325 458 1.6E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 2.4E-16 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF54791 557 624 6.53E-14 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF50249 610 696 3.6E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF00575 S1 RNA binding domain 620 692 5.2E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 693 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Gene3D G3DSA:1.10.10.400 254 309 3.0E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SMART SM00322 554 619 9.4E-11 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF00013 KH domain 558 615 4.1E-10 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 PIRSF PIRSF005499 1 703 1.5E-295 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF55666 455 562 1.59E-27 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Gene3D G3DSA:3.30.1370.10 566 628 1.4E-12 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Gene3D G3DSA:3.30.230.70 310 565 4.8E-61 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF54211 5 144 2.02E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SUPERFAMILY SSF54211 296 490 3.29E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF03725 3' exoribonuclease family, domain 2 461 531 3.0E-6 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Pfam PF03725 3' exoribonuclease family, domain 2 148 210 1.1E-11 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 SMART SM00316 622 692 2.6E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS06125 bc8bfeac9f2821a3e88e641f4c19326f 703 Gene3D G3DSA:3.30.230.70 11 253 1.6E-54 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 Pfam PF00206 Lyase 82 304 7.2E-24 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 Gene3D G3DSA:1.10.275.10 6 105 2.7E-22 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 SMART SM00998 373 457 5.6E-30 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 SUPERFAMILY SSF48557 12 458 1.01E-95 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 456 4.9E-118 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 Gene3D G3DSA:1.20.200.10 106 477 8.5E-96 T 29-03-2018 CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 5.1E-10 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 5.1E-10 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 PRINTS PR00149 Fumarate lyase superfamily signature 241 268 5.1E-10 T 29-03-2018 IPR000362 Fumarate lyase family CWR56_RS06210 044536e832365a25ea2a0ec1bda51d0e 481 Pfam PF10397 Adenylosuccinate lyase C-terminus 374 455 2.2E-18 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS18575 87f3e00cd04763a790a34a3ddcad9c3d 116 PIRSF PIRSF004555 13 116 9.8E-41 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR56_RS18575 87f3e00cd04763a790a34a3ddcad9c3d 116 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 12 115 5.8E-30 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR56_RS18575 87f3e00cd04763a790a34a3ddcad9c3d 116 Pfam PF02575 YbaB/EbfC DNA-binding family 21 111 1.1E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR56_RS18575 87f3e00cd04763a790a34a3ddcad9c3d 116 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 15 109 23.271 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR56_RS18575 87f3e00cd04763a790a34a3ddcad9c3d 116 Gene3D G3DSA:3.30.1310.10 8 116 6.5E-40 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR56_RS18575 87f3e00cd04763a790a34a3ddcad9c3d 116 SUPERFAMILY SSF82607 21 115 3.4E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR56_RS09200 49d647bd2e2395507c495ff42765a34f 123 Pfam PF13840 ACT domain 55 116 4.3E-23 T 29-03-2018 IPR027795 GATS-like ACT domain CWR56_RS09200 49d647bd2e2395507c495ff42765a34f 123 Gene3D G3DSA:3.30.2130.10 1 123 1.1E-31 T 29-03-2018 CWR56_RS09200 49d647bd2e2395507c495ff42765a34f 123 PIRSF PIRSF008459 1 123 4.4E-47 T 29-03-2018 IPR016540 Uncharacterised conserved protein UCP008459 CWR56_RS09200 49d647bd2e2395507c495ff42765a34f 123 SUPERFAMILY SSF55021 1 56 1.1E-17 T 29-03-2018 CWR56_RS09200 49d647bd2e2395507c495ff42765a34f 123 SUPERFAMILY SSF55021 58 122 6.2E-20 T 29-03-2018 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 SUPERFAMILY SSF54292 2 89 1.09E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 Gene3D G3DSA:3.10.20.30 1 112 2.9E-22 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 SUPERFAMILY SSF53067 270 315 4.49E-8 T 29-03-2018 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 SUPERFAMILY SSF53067 359 427 4.49E-8 T 29-03-2018 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 SUPERFAMILY SSF53067 212 242 4.49E-8 T 29-03-2018 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 SUPERFAMILY SSF53067 468 495 4.49E-8 T 29-03-2018 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 Gene3D G3DSA:3.30.420.40 201 400 1.9E-8 T 29-03-2018 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 79 8.5E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS03535 1a97954c9d5cf1ffeb5afafa8a538623 642 Pfam PF14574 Domain of unknown function (DUF4445) 212 623 2.2E-139 T 29-03-2018 IPR027980 Protein of unknown function DUF4445 CWR56_RS05275 7eff58f97ab682e96daa06afb8b86f3c 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS05275 7eff58f97ab682e96daa06afb8b86f3c 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.613 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05275 7eff58f97ab682e96daa06afb8b86f3c 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 1.9E-39 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05275 7eff58f97ab682e96daa06afb8b86f3c 103 SUPERFAMILY SSF141091 1 102 1.7E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05275 7eff58f97ab682e96daa06afb8b86f3c 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 5.3E-43 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS10785 0b09fd8c4347d16645524b0c1e84bd12 673 Pfam PF13515 Fusaric acid resistance protein-like 382 503 2.4E-14 T 29-03-2018 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 SUPERFAMILY SSF47384 80 158 9.61E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 SUPERFAMILY SSF55874 148 310 1.05E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 204 310 1.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 239 253 1.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 290 1.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 309 1.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 257 267 1.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 SMART SM00387 203 311 1.8E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 SMART SM00388 91 157 5.9E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 Gene3D G3DSA:3.30.565.10 152 311 8.5E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 Gene3D G3DSA:1.10.287.130 82 151 4.7E-11 T 29-03-2018 CWR56_RS04020 49af033d4bb84a91b78dde001ac89956 311 Pfam PF00512 His Kinase A (phospho-acceptor) domain 93 153 8.8E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12030 2e7faacad5dd69e37e533d7bf9673c3a 613 Gene3D G3DSA:3.30.70.270 453 608 1.9E-34 T 29-03-2018 CWR56_RS12030 2e7faacad5dd69e37e533d7bf9673c3a 613 Pfam PF00990 Diguanylate cyclase, GGDEF domain 458 603 9.3E-31 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS12030 2e7faacad5dd69e37e533d7bf9673c3a 613 Gene3D G3DSA:1.25.40.10 190 452 1.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS12030 2e7faacad5dd69e37e533d7bf9673c3a 613 SMART SM00267 446 607 1.7E-30 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS12030 2e7faacad5dd69e37e533d7bf9673c3a 613 SUPERFAMILY SSF55073 462 608 1.57E-33 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS12030 2e7faacad5dd69e37e533d7bf9673c3a 613 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 454 604 5.0E-35 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 SMART SM00872 277 355 2.5E-8 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 SUPERFAMILY SSF88713 3 271 4.82E-56 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 Pfam PF09261 Alpha mannosidase middle domain 278 355 5.8E-7 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 Gene3D G3DSA:1.20.1270.50 277 372 1.2E-17 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 Gene3D G3DSA:3.20.110.10 1 202 5.3E-56 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 Gene3D G3DSA:2.60.40.1180 373 508 2.6E-17 T 29-03-2018 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 385 867 1.7E-39 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 SUPERFAMILY SSF88688 278 378 1.08E-8 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 5 270 2.5E-50 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CWR56_RS12990 0b9d5ec8a174142f042559609520fdd3 892 SUPERFAMILY SSF74650 371 878 1.02E-70 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS00880 73efe9dff4dfc40bf64f9aedf2aa4a07 274 SUPERFAMILY SSF52540 1 112 4.16E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00880 73efe9dff4dfc40bf64f9aedf2aa4a07 274 Gene3D G3DSA:3.40.50.300 1 137 4.6E-8 T 29-03-2018 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 Gene3D G3DSA:1.20.1250.20 16 213 2.7E-35 T 29-03-2018 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 Pfam PF07690 Major Facilitator Superfamily 24 426 7.5E-55 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 Gene3D G3DSA:1.20.120.330 671 801 3.0E-5 T 29-03-2018 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 SUPERFAMILY SSF103473 9 208 1.44E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 SUPERFAMILY SSF103473 263 438 1.44E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 Gene3D G3DSA:1.20.1250.20 280 445 7.2E-17 T 29-03-2018 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 Gene3D G3DSA:3.90.20.10 446 670 3.0E-14 T 29-03-2018 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 SUPERFAMILY SSF57997 570 775 5.1E-7 T 29-03-2018 CWR56_RS06445 f1ee6d196bc28f81fff34ecd8c6af86a 830 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CWR56_RS06150 01f3eb0f246705234c5f098273cb1605 244 Gene3D G3DSA:3.90.226.10 29 244 3.2E-24 T 29-03-2018 CWR56_RS06150 01f3eb0f246705234c5f098273cb1605 244 Pfam PF00574 Clp protease 51 221 1.0E-29 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CWR56_RS06150 01f3eb0f246705234c5f098273cb1605 244 SUPERFAMILY SSF52096 41 229 1.72E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS06150 01f3eb0f246705234c5f098273cb1605 244 PRINTS PR00127 Clp protease catalytic subunit P signature 199 218 2.0E-7 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS06150 01f3eb0f246705234c5f098273cb1605 244 PRINTS PR00127 Clp protease catalytic subunit P signature 86 106 2.0E-7 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS06150 01f3eb0f246705234c5f098273cb1605 244 PRINTS PR00127 Clp protease catalytic subunit P signature 117 134 2.0E-7 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 SUPERFAMILY SSF88946 2 95 3.77E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 Gene3D G3DSA:1.10.1740.10 1 95 8.1E-21 T 29-03-2018 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 165 5.2E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 SUPERFAMILY SSF88659 103 167 9.53E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 Pfam PF04542 Sigma-70 region 2 21 87 6.0E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 Pfam PF08281 Sigma-70, region 4 112 162 1.1E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS08940 f4642898d29edd79d0ddf64b344d23aa 171 Gene3D G3DSA:1.10.10.10 96 171 4.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14640 9ee88abea2974e13d6d461ce1e7fec0b 243 Pfam PF04794 YdjC-like protein 3 231 1.9E-54 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like CWR56_RS14640 9ee88abea2974e13d6d461ce1e7fec0b 243 SUPERFAMILY SSF88713 1 243 3.56E-67 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS14640 9ee88abea2974e13d6d461ce1e7fec0b 243 Gene3D G3DSA:3.20.20.370 1 243 4.4E-70 T 29-03-2018 CWR56_RS14340 8ff41d3353e48c952791862f751f67e4 176 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CWR56_RS14340 8ff41d3353e48c952791862f751f67e4 176 SUPERFAMILY SSF52218 1 117 4.19E-17 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS14340 8ff41d3353e48c952791862f751f67e4 176 Gene3D G3DSA:3.40.50.360 1 175 2.0E-20 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS14340 8ff41d3353e48c952791862f751f67e4 176 Pfam PF12641 Flavodoxin domain 4 166 3.4E-58 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 Gene3D G3DSA:1.10.287.950 362 559 9.3E-45 T 29-03-2018 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 Gene3D G3DSA:1.10.287.950 151 361 3.8E-14 T 29-03-2018 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 SMART SM00304 209 262 1.1E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 368 521 1.1E-40 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 Pfam PF12729 Four helix bundle sensory module for signal transduction 8 163 2.1E-8 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 SUPERFAMILY SSF58104 328 558 1.83E-61 T 29-03-2018 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 SUPERFAMILY SSF58104 229 264 1.83E-61 T 29-03-2018 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 3.3E-29 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 433 3.3E-29 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 3.3E-29 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 483 512 3.3E-29 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CWR56_RS02470 4180d5c2b1bf7988210d25136403d3b4 567 SMART SM00283 308 555 1.2E-67 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CWR56_RS00600 04b709593ff4c7769ab67ebcb9ec8296 86 Gene3D G3DSA:1.10.10.10 1 80 7.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00600 04b709593ff4c7769ab67ebcb9ec8296 86 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 3 81 1.4E-39 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CWR56_RS00600 04b709593ff4c7769ab67ebcb9ec8296 86 Pfam PF12116 Stage III sporulation protein D 3 82 1.2E-41 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CWR56_RS00600 04b709593ff4c7769ab67ebcb9ec8296 86 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWR56_RS01380 77f1fe3d11c9b2bcf969a74d9f103985 253 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 180 250 3.6E-20 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CWR56_RS01380 77f1fe3d11c9b2bcf969a74d9f103985 253 SUPERFAMILY SSF117143 89 212 2.35E-19 T 29-03-2018 CWR56_RS01380 77f1fe3d11c9b2bcf969a74d9f103985 253 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 5.6E-36 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CWR56_RS01380 77f1fe3d11c9b2bcf969a74d9f103985 253 Pfam PF00460 Flagella basal body rod protein 5 35 4.2E-12 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CWR56_RS01380 77f1fe3d11c9b2bcf969a74d9f103985 253 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CWR56_RS14765 e7e963fb4a6dc79682635e5349d7dbff 196 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 7 191 4.6E-79 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CWR56_RS14765 e7e963fb4a6dc79682635e5349d7dbff 196 Gene3D G3DSA:3.40.50.1950 7 191 3.5E-24 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR56_RS14765 e7e963fb4a6dc79682635e5349d7dbff 196 Pfam PF02441 Flavoprotein 7 164 1.2E-16 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR56_RS14765 e7e963fb4a6dc79682635e5349d7dbff 196 PIRSF PIRSF001390 1 196 7.7E-76 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CWR56_RS14765 e7e963fb4a6dc79682635e5349d7dbff 196 SUPERFAMILY SSF52507 8 190 2.62E-33 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 96 22.271 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 SUPERFAMILY SSF50104 1 98 1.54E-37 T 29-03-2018 IPR008991 Translation protein SH3-like domain CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 Gene3D G3DSA:2.30.30.30 1 91 2.1E-37 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 4.3E-29 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 Pfam PF00467 KOW motif 5 36 1.1E-8 T 29-03-2018 IPR005824 KOW CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 SMART SM00739 2 29 2.8E-6 T 29-03-2018 IPR005824 KOW CWR56_RS00140 cbd2f3db8280858488f41b5a355ff8e2 101 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 2.0E-39 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 SUPERFAMILY SSF53448 1 541 2.25E-161 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF12919 TcdA/TcdB catalytic glycosyltransferase domain 96 468 7.0E-137 T 29-03-2018 IPR024770 TcdA/TcdB toxin, catalytic glycosyltransferase domain GO:0016757 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF01473 Putative cell wall binding repeat 1988 2005 0.0044 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF01473 Putative cell wall binding repeat 2104 2117 0.86 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF01473 Putative cell wall binding repeat 2260 2271 0.52 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF01473 Putative cell wall binding repeat 1971 1985 0.028 T 29-03-2018 IPR018337 Cell wall/choline-binding repeat CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 SUPERFAMILY SSF69360 2188 2358 3.69E-32 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.20.120.10 2335 2363 3.8E-8 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.20.120.10 2222 2246 1.6E-7 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.20.120.10 2069 2089 2.6E-5 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.20.120.10 1865 1910 1.5E-8 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF12918 TcdB toxin N-terminal helical domain 22 83 2.7E-16 T 29-03-2018 IPR024772 TcdA/TcdB toxin, N-terminal helical domain CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.10.270.10 2152 2221 2.6E-6 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 SUPERFAMILY SSF69360 1853 2079 2.35E-43 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.30.30.20 2021 2068 1.7E-7 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.30.30.20 2247 2266 1.4E-8 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.30.30.20 2090 2111 5.1E-4 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.30.30.20 2289 2334 1.1E-5 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.30.30.20 2267 2288 4.0E-8 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF11713 Peptidase C80 family 575 754 1.8E-50 T 29-03-2018 IPR020974 CGT/MARTX, cysteine protease (CPD) domain CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.10.270.10 1802 1864 2.4E-6 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Pfam PF12920 TcdA/TcdB pore forming domain 862 1528 8.2E-240 T 29-03-2018 IPR024769 TcdA/TcdB toxin, pore forming domain GO:0009405 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 SUPERFAMILY SSF69360 2056 2172 1.57E-23 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.10.270.10 1924 1977 3.5E-11 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.10.270.10 1978 2020 1.5E-14 T 29-03-2018 CWR56_RS03130 4fa9f76c5e8c8db5542f2af4119d27cc 2366 Gene3D G3DSA:2.10.270.10 2112 2151 3.3E-11 T 29-03-2018 CWR56_RS11105 7e59501b314f054d667fe8ed0cdbaf75 373 Gene3D G3DSA:1.10.260.40 1 370 8.0E-5 T 29-03-2018 CWR56_RS11105 7e59501b314f054d667fe8ed0cdbaf75 373 Pfam PF02486 Replication initiation factor 138 343 2.2E-70 T 29-03-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 CWR56_RS00890 7905efcdc6aed26eab9aacc20ec4aeb6 196 Pfam PF05569 BlaR1 peptidase M56 1 92 1.6E-20 T 29-03-2018 IPR008756 Peptidase M56 CWR56_RS05045 a396da3e90401ef9eaf5c6d28394f38a 459 Pfam PF14501 GHKL domain 344 449 5.2E-21 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS05045 a396da3e90401ef9eaf5c6d28394f38a 459 SUPERFAMILY SSF55874 316 450 1.34E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS05045 a396da3e90401ef9eaf5c6d28394f38a 459 Gene3D G3DSA:3.30.565.10 306 455 9.0E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14815 e0f9eb169f1ac178569402ea781073e0 773 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 12 207 1.3E-24 T 29-03-2018 IPR006483 CRISPR-associated Cas3-HD domain CWR56_RS14815 e0f9eb169f1ac178569402ea781073e0 773 Gene3D G3DSA:3.40.50.300 234 406 6.0E-11 T 29-03-2018 CWR56_RS14815 e0f9eb169f1ac178569402ea781073e0 773 SUPERFAMILY SSF52540 245 558 4.05E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14815 e0f9eb169f1ac178569402ea781073e0 773 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 249 593 8.8E-67 T 29-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core CWR56_RS14815 e0f9eb169f1ac178569402ea781073e0 773 Gene3D G3DSA:3.40.50.300 439 584 1.3E-8 T 29-03-2018 CWR56_RS14815 e0f9eb169f1ac178569402ea781073e0 773 SMART SM00487 230 438 0.0034 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS18120 ad7e38de589583b6af910b38f64c1895 207 Pfam PF01380 SIS domain 51 146 7.6E-14 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS18120 ad7e38de589583b6af910b38f64c1895 207 Gene3D G3DSA:3.40.50.10490 2 207 2.4E-39 T 29-03-2018 CWR56_RS18120 ad7e38de589583b6af910b38f64c1895 207 SUPERFAMILY SSF53697 7 203 5.29E-37 T 29-03-2018 CWR56_RS18170 7f44dcf6a47a95d157319b5030fcac9e 319 Pfam PF03358 NADPH-dependent FMN reductase 3 181 5.7E-38 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS18170 7f44dcf6a47a95d157319b5030fcac9e 319 Gene3D G3DSA:3.40.50.360 1 215 2.5E-24 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS18170 7f44dcf6a47a95d157319b5030fcac9e 319 SUPERFAMILY SSF52218 3 204 5.28E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS00670 80da650f16e1c0459a7ef39217bae42a 350 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 12 210 4.8E-78 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWR56_RS00670 80da650f16e1c0459a7ef39217bae42a 350 Pfam PF01546 Peptidase family M20/M25/M40 82 345 3.0E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS00670 80da650f16e1c0459a7ef39217bae42a 350 SUPERFAMILY SSF53187 266 349 1.89E-62 T 29-03-2018 CWR56_RS00670 80da650f16e1c0459a7ef39217bae42a 350 SUPERFAMILY SSF53187 5 183 1.89E-62 T 29-03-2018 CWR56_RS00670 80da650f16e1c0459a7ef39217bae42a 350 Gene3D G3DSA:3.40.630.10 1 350 5.0E-49 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00091 322 393 5.5E-4 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00091 452 523 0.016 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.70.270 842 1008 4.3E-45 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.450.20 448 570 1.0E-22 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.450.20 571 710 3.6E-17 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00086 657 699 4.9E-5 T 29-03-2018 IPR001610 PAC motif CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00086 529 570 0.018 T 29-03-2018 IPR001610 PAC motif CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00086 793 835 260.0 T 29-03-2018 IPR001610 PAC motif CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00086 399 440 0.21 T 29-03-2018 IPR001610 PAC motif CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Pfam PF13426 PAS domain 640 698 2.8E-4 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Pfam PF13426 PAS domain 465 569 9.8E-11 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SUPERFAMILY SSF55785 329 442 1.77E-19 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.450.20 311 447 7.1E-23 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SUPERFAMILY SSF55785 633 702 3.14E-10 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SUPERFAMILY SSF55785 437 568 4.54E-18 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 843 1005 8.7E-39 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SUPERFAMILY SSF55073 851 1009 4.47E-40 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.450.20 154 287 1.1E-19 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SUPERFAMILY SSF103190 52 178 3.3E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.450.20 711 841 4.2E-5 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 SMART SM00267 835 1007 1.1E-46 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Pfam PF00990 Diguanylate cyclase, GGDEF domain 846 1002 2.2E-39 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Pfam PF02743 Cache domain 37 271 1.8E-21 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 342 446 4.0E-12 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 467 577 1.6E-14 T 29-03-2018 IPR000014 PAS domain CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Gene3D G3DSA:3.30.450.20 55 153 1.4E-13 T 29-03-2018 CWR56_RS08885 11125ea9f19e7b9d50f3431fd5a25d9c 1145 Pfam PF08447 PAS fold 348 431 3.3E-17 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 SUPERFAMILY SSF54631 249 369 1.39E-27 T 29-03-2018 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 Pfam PF00005 ABC transporter 17 164 2.9E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 Gene3D G3DSA:3.10.580.10 261 375 1.9E-26 T 29-03-2018 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 SUPERFAMILY SSF52540 1 241 2.5E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 Gene3D G3DSA:3.40.50.300 1 260 1.2E-79 T 29-03-2018 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 SMART SM00116 258 306 6.2E-5 T 29-03-2018 IPR000644 CBS domain CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 SMART SM00116 318 366 7.8E-8 T 29-03-2018 IPR000644 CBS domain CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 Pfam PF00571 CBS domain 251 301 1.5E-6 T 29-03-2018 IPR000644 CBS domain CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 Pfam PF00571 CBS domain 312 366 2.9E-12 T 29-03-2018 IPR000644 CBS domain CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 9 367 4.1E-118 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CWR56_RS04425 b7acc373a7c023af266920b3a2e12192 378 SMART SM00382 26 214 1.0E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15445 8b5c59b703801d0484abf634939b062a 439 PIRSF PIRSF006060 2 439 8.8E-75 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS15445 8b5c59b703801d0484abf634939b062a 439 Pfam PF13520 Amino acid permease 7 398 5.0E-57 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS02095 1ae6f933234850347b59c4799f26a3a6 317 Pfam PF00905 Penicillin binding protein transpeptidase domain 85 309 1.5E-33 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR56_RS02095 1ae6f933234850347b59c4799f26a3a6 317 ProSitePatterns PS00337 Beta-lactamase class-D active site. 105 115 - T 29-03-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 CWR56_RS02095 1ae6f933234850347b59c4799f26a3a6 317 SUPERFAMILY SSF56601 76 313 4.27E-36 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS02095 1ae6f933234850347b59c4799f26a3a6 317 Gene3D G3DSA:3.40.710.10 45 317 1.0E-30 T 29-03-2018 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 Gene3D G3DSA:3.40.50.720 2 159 8.5E-28 T 29-03-2018 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 Gene3D G3DSA:3.90.110.10 160 434 4.5E-83 T 29-03-2018 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 SUPERFAMILY SSF51735 4 166 2.19E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 SUPERFAMILY SSF56327 173 434 2.64E-84 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 410 2.0E-47 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 7.3E-48 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS14645 e9bc0b126994c5818b1426ed6e126805 436 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 8.2E-71 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS03065 31e66b42cd99e3bae42e9d5539837aca 669 Gene3D G3DSA:2.120.10.30 266 395 5.4E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CWR56_RS03065 31e66b42cd99e3bae42e9d5539837aca 669 SUPERFAMILY SSF53474 407 661 2.17E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS03065 31e66b42cd99e3bae42e9d5539837aca 669 Gene3D G3DSA:3.40.50.1820 396 667 2.8E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS03065 31e66b42cd99e3bae42e9d5539837aca 669 Pfam PF00326 Prolyl oligopeptidase family 452 664 2.3E-47 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CWR56_RS03065 31e66b42cd99e3bae42e9d5539837aca 669 Gene3D G3DSA:2.130.10.150 15 265 5.3E-15 T 29-03-2018 CWR56_RS03065 31e66b42cd99e3bae42e9d5539837aca 669 SUPERFAMILY SSF82171 15 407 2.88E-21 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 Gene3D G3DSA:1.20.1250.20 258 462 5.7E-28 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 Gene3D G3DSA:1.20.1250.20 4 198 4.5E-36 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 Pfam PF07690 Major Facilitator Superfamily 18 408 1.2E-59 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 4.3E-9 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 4.3E-9 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 4.3E-9 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 4.3E-9 T 29-03-2018 CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 SUPERFAMILY SSF103473 247 461 4.05E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 SUPERFAMILY SSF103473 7 196 4.05E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS12660 3536c25cf1e5b3344e34b4f74a84b0be 466 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 426 8.4E-100 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR56_RS09310 a463d0f241d324c9f50266c212f469c1 228 Gene3D G3DSA:3.40.50.300 1 226 1.1E-60 T 29-03-2018 CWR56_RS09310 a463d0f241d324c9f50266c212f469c1 228 Pfam PF00005 ABC transporter 23 170 2.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09310 a463d0f241d324c9f50266c212f469c1 228 SMART SM00382 32 226 2.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09310 a463d0f241d324c9f50266c212f469c1 228 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS09310 a463d0f241d324c9f50266c212f469c1 228 SUPERFAMILY SSF52540 4 224 1.12E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01945 f80812db0c40c27169596359e67a8182 687 Pfam PF13175 AAA ATPase domain 1 364 1.1E-22 T 29-03-2018 CWR56_RS01945 f80812db0c40c27169596359e67a8182 687 Gene3D G3DSA:3.40.50.300 1 405 1.7E-24 T 29-03-2018 CWR56_RS01945 f80812db0c40c27169596359e67a8182 687 SUPERFAMILY SSF52540 1 367 1.03E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 641 1.7E-175 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 SUPERFAMILY SSF52540 3 165 7.1E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 Pfam PF02421 Ferrous iron transport protein B 4 155 1.3E-65 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 Pfam PF07670 Nucleoside recognition 355 449 6.5E-13 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 Pfam PF07670 Nucleoside recognition 516 645 3.6E-28 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 Pfam PF07664 Ferrous iron transport protein B C terminus 459 511 1.1E-23 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 Gene3D G3DSA:3.40.50.300 2 293 5.1E-35 T 29-03-2018 CWR56_RS06965 c7d2a93f47b9fc350ff5da753a91f7c9 718 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 155 1.4E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 Gene3D G3DSA:1.10.1140.10 358 457 5.7E-17 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 74 1.9E-5 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 SUPERFAMILY SSF52540 80 354 4.2E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 Gene3D G3DSA:3.40.50.300 35 349 3.1E-83 T 29-03-2018 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 SUPERFAMILY SSF47917 362 419 8.89E-5 T 29-03-2018 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 PIRSF PIRSF039114 1 457 1.5E-235 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 457 58.519 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14695 eec26566f5ec277f89b25a082867e2cf 457 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 3.3E-66 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS01155 58de8c524de25c69a1260a91a5e09730 91 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 18 88 2.7E-13 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CWR56_RS01155 58de8c524de25c69a1260a91a5e09730 91 SUPERFAMILY SSF101498 8 89 1.7E-14 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CWR56_RS01155 58de8c524de25c69a1260a91a5e09730 91 Pfam PF04316 Anti-sigma-28 factor, FlgM 35 87 1.9E-15 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CWR56_RS01155 58de8c524de25c69a1260a91a5e09730 91 Gene3D G3DSA:1.10.287.1160 58 87 4.6E-12 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CWR56_RS15755 ad564d18110777416eb672a861f555b4 380 SUPERFAMILY SSF52540 6 370 9.27E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15755 ad564d18110777416eb672a861f555b4 380 Pfam PF01935 Domain of unknown function DUF87 30 235 9.8E-11 T 29-03-2018 IPR002789 Helicase HerA, central domain CWR56_RS15755 ad564d18110777416eb672a861f555b4 380 Gene3D G3DSA:3.40.50.300 5 373 1.1E-20 T 29-03-2018 CWR56_RS18345 f5e17fcb77c189072590cb5167cf7ab9 92 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 91 3.2E-27 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18345 f5e17fcb77c189072590cb5167cf7ab9 92 Gene3D G3DSA:3.30.70.60 2 92 5.8E-29 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CWR56_RS18345 f5e17fcb77c189072590cb5167cf7ab9 92 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 92 17.674 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR56_RS18345 f5e17fcb77c189072590cb5167cf7ab9 92 Pfam PF01250 Ribosomal protein S6 3 90 7.7E-30 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18345 f5e17fcb77c189072590cb5167cf7ab9 92 SUPERFAMILY SSF54995 2 90 3.79E-29 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 153 365 2.9E-61 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 Pfam PF01872 RibD C-terminal domain 156 363 4.2E-48 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 14 363 3.4E-107 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 SUPERFAMILY SSF53927 10 151 1.04E-45 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 SUPERFAMILY SSF53597 154 364 1.37E-56 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 95 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 Gene3D G3DSA:3.40.140.10 5 131 2.3E-33 T 29-03-2018 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 Gene3D G3DSA:3.40.430.10 132 366 1.4E-68 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 106 5.2E-22 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR56_RS08130 0dec1dedf83accd25d5476fb87d7089c 370 PIRSF PIRSF006769 5 370 3.8E-129 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CWR56_RS17280 b68ada47d650358ba2a097d6648c76fb 86 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 12 83 3.0E-14 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17280 b68ada47d650358ba2a097d6648c76fb 86 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 1.1E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17280 b68ada47d650358ba2a097d6648c76fb 86 SUPERFAMILY SSF51344 5 85 8.76E-20 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17280 b68ada47d650358ba2a097d6648c76fb 86 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 6 85 1.9E-19 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17280 b68ada47d650358ba2a097d6648c76fb 86 Gene3D G3DSA:2.60.15.10 1 86 1.4E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS03710 8db31de39647a80b4372bc5d7e02685a 186 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 7 184 1.2E-86 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CWR56_RS03710 8db31de39647a80b4372bc5d7e02685a 186 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 9 174 5.5E-76 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CWR56_RS03710 8db31de39647a80b4372bc5d7e02685a 186 PIRSF PIRSF038321 5 185 2.5E-88 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CWR56_RS01870 ac7d0f6ce974034bde3fa6c459debc34 198 TIGRFAM TIGR04100 rSAM_pair_X: radical SAM enzyme, TIGR04100 family 3 197 6.3E-95 T 29-03-2018 IPR023822 Radical SAM, TatD-associated, bacteria CWR56_RS01870 ac7d0f6ce974034bde3fa6c459debc34 198 SUPERFAMILY SSF102114 10 193 1.7E-27 T 29-03-2018 CWR56_RS01870 ac7d0f6ce974034bde3fa6c459debc34 198 TIGRFAM TIGR04038 tatD_link_rSAM: radical SAM protein, TatD family-associated 3 196 1.1E-64 T 29-03-2018 IPR023821 Radical SAM, TatD-associated CWR56_RS01870 ac7d0f6ce974034bde3fa6c459debc34 198 Pfam PF13394 4Fe-4S single cluster domain 13 122 4.5E-13 T 29-03-2018 CWR56_RS01870 ac7d0f6ce974034bde3fa6c459debc34 198 Pfam PF04055 Radical SAM superfamily 13 180 1.2E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS01870 ac7d0f6ce974034bde3fa6c459debc34 198 Gene3D G3DSA:3.20.20.70 7 196 4.7E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 SUPERFAMILY SSF55874 623 758 3.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 SMART SM00387 665 772 1.9E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 SMART SM00388 553 619 5.7E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 Gene3D G3DSA:1.10.287.130 544 613 2.7E-17 T 29-03-2018 CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 Gene3D G3DSA:3.30.565.10 614 771 9.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 SUPERFAMILY SSF47384 540 620 1.33E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 Pfam PF00512 His Kinase A (phospho-acceptor) domain 553 619 6.9E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12995 bdcb0e007a858ce1370bd67158d4d101 773 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 666 768 5.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14220 a7d67a6a3dc4576cf73c01e2692fbdbf 373 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 2.0E-98 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR56_RS14220 a7d67a6a3dc4576cf73c01e2692fbdbf 373 Gene3D G3DSA:3.20.20.105 1 372 8.8E-170 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR56_RS14220 a7d67a6a3dc4576cf73c01e2692fbdbf 373 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 5.4E-174 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR56_RS14220 a7d67a6a3dc4576cf73c01e2692fbdbf 373 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 59.589 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR56_RS14220 a7d67a6a3dc4576cf73c01e2692fbdbf 373 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 372 4.2E-182 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR56_RS14220 a7d67a6a3dc4576cf73c01e2692fbdbf 373 SUPERFAMILY SSF51713 2 369 1.57E-171 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Pfam PF11987 Translation-initiation factor 2 432 536 1.6E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 SUPERFAMILY SSF52540 135 319 2.74E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 60 645 1.3E-254 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 SUPERFAMILY SSF50447 550 644 6.45E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 SUPERFAMILY SSF50447 319 401 3.95E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Gene3D G3DSA:3.40.50.10050 444 525 1.4E-28 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 51 6.5E-11 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 67 116 2.0E-12 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Gene3D G3DSA:3.30.56.50 4 45 1.7E-9 T 29-03-2018 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Gene3D G3DSA:3.30.56.50 68 108 9.5E-8 T 29-03-2018 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 SUPERFAMILY SSF52156 425 553 3.14E-37 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 644 16.92 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 ProSitePatterns PS01176 Initiation factor 2 signature. 597 619 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 149 305 1.2E-35 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Gene3D G3DSA:2.40.30.10 315 412 2.4E-14 T 29-03-2018 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Gene3D G3DSA:2.40.30.10 547 645 3.4E-30 T 29-03-2018 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Pfam PF00009 Elongation factor Tu GTP binding domain 151 307 2.3E-35 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS06085 241743bcb4917047e5bc2d6387b5ca2a 646 Gene3D G3DSA:3.40.50.300 141 314 1.3E-42 T 29-03-2018 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 Gene3D G3DSA:3.40.50.2030 357 530 5.4E-66 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 PIRSF PIRSF000076 4 530 1.7E-212 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 4 529 3.2E-219 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 Gene3D G3DSA:3.40.50.2030 210 356 9.3E-66 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 Gene3D G3DSA:1.20.1270.20 126 207 5.4E-25 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 Hamap MF_00069 Hydroxylamine reductase [hcp]. 4 530 20.117 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 Pfam PF03063 Prismane/CO dehydrogenase family 4 526 3.3E-171 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 SUPERFAMILY SSF56821 4 529 7.48E-183 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 CWR56_RS10455 fd2c015f839193ddae06164461841d5c 530 Gene3D G3DSA:1.20.1270.20 1 97 1.7E-30 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS09965 4ce039578f635ef65b8d24354f467555 361 Gene3D G3DSA:3.30.70.20 298 354 9.9E-12 T 29-03-2018 CWR56_RS09965 4ce039578f635ef65b8d24354f467555 361 SUPERFAMILY SSF54862 282 350 1.38E-15 T 29-03-2018 CWR56_RS09965 4ce039578f635ef65b8d24354f467555 361 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 286 4.7E-47 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR56_RS09965 4ce039578f635ef65b8d24354f467555 361 SUPERFAMILY SSF51395 3 286 2.97E-58 T 29-03-2018 CWR56_RS09965 4ce039578f635ef65b8d24354f467555 361 Pfam PF01180 Dihydroorotate dehydrogenase 3 270 3.9E-30 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR56_RS09965 4ce039578f635ef65b8d24354f467555 361 Gene3D G3DSA:3.20.20.70 1 295 7.1E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS03760 dc2d57febabf3992ea7a35235cef6070 337 Gene3D G3DSA:3.40.47.10 48 214 1.2E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS03760 dc2d57febabf3992ea7a35235cef6070 337 PIRSF PIRSF011570 3 337 1.3E-154 T 29-03-2018 IPR010894 Stage V sporulation AD CWR56_RS03760 dc2d57febabf3992ea7a35235cef6070 337 SUPERFAMILY SSF53901 58 312 2.28E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS03760 dc2d57febabf3992ea7a35235cef6070 337 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 7 334 4.9E-160 T 29-03-2018 IPR010894 Stage V sporulation AD CWR56_RS03760 dc2d57febabf3992ea7a35235cef6070 337 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 8 334 1.6E-146 T 29-03-2018 IPR010894 Stage V sporulation AD CWR56_RS04540 940c0f6f346cc0fb5c625147f9fb855f 331 SUPERFAMILY SSF53850 67 310 3.53E-23 T 29-03-2018 CWR56_RS04540 940c0f6f346cc0fb5c625147f9fb855f 331 Pfam PF09084 NMT1/THI5 like 81 264 7.8E-11 T 29-03-2018 IPR015168 SsuA/THI5-like CWR56_RS04540 940c0f6f346cc0fb5c625147f9fb855f 331 Gene3D G3DSA:3.40.190.10 134 314 2.4E-16 T 29-03-2018 CWR56_RS04540 940c0f6f346cc0fb5c625147f9fb855f 331 Gene3D G3DSA:3.40.190.10 24 115 0.037 T 29-03-2018 CWR56_RS04540 940c0f6f346cc0fb5c625147f9fb855f 331 PIRSF PIRSF027386 1 330 1.3E-113 T 29-03-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type CWR56_RS10405 f52af829d87500ee924238f1845b46a6 261 Pfam PF06541 Putative ABC-transporter type IV 8 160 1.2E-50 T 29-03-2018 IPR010540 Putative ABC-transporter type IV CmpB/TMEM229 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 Gene3D G3DSA:2.60.120.10 2 498 1.7E-57 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 SUPERFAMILY SSF46689 496 547 1.34E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 512 527 2.1E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 527 543 2.1E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 Gene3D G3DSA:1.10.10.60 499 550 1.7E-12 T 29-03-2018 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 SMART SM00342 460 543 6.0E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 Pfam PF10114 Sensory domain found in PocR 128 282 1.9E-17 T 29-03-2018 IPR018771 PocR domain CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 Pfam PF12833 Helix-turn-helix domain 468 544 1.3E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 SUPERFAMILY SSF51182 9 163 2.75E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS09555 1aa0bb68c78211f8ddb1bd696957d238 551 Pfam PF07883 Cupin domain 38 104 7.3E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS13110 17f550c00b28b65f00410fc891b1dbfb 591 Gene3D G3DSA:2.30.310.10 1 168 2.4E-49 T 29-03-2018 CWR56_RS13110 17f550c00b28b65f00410fc891b1dbfb 591 Pfam PF05670 Domain of unknown function (DUF814) 470 557 2.4E-31 T 29-03-2018 IPR008532 Domain of unknown function DUF814 CWR56_RS13110 17f550c00b28b65f00410fc891b1dbfb 591 Gene3D G3DSA:3.40.970.40 254 306 7.8E-13 T 29-03-2018 CWR56_RS13110 17f550c00b28b65f00410fc891b1dbfb 591 SUPERFAMILY SSF46946 177 243 3.27E-10 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CWR56_RS13110 17f550c00b28b65f00410fc891b1dbfb 591 Gene3D G3DSA:1.10.8.50 169 250 1.8E-16 T 29-03-2018 CWR56_RS13110 17f550c00b28b65f00410fc891b1dbfb 591 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 460 5.2E-160 T 29-03-2018 CWR56_RS09405 b8c0a8249f7df23d9ce81066cdf8caf1 86 SUPERFAMILY SSF50182 7 73 5.11E-23 T 29-03-2018 IPR010920 LSM domain CWR56_RS09405 b8c0a8249f7df23d9ce81066cdf8caf1 86 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 7 67 2.4E-28 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CWR56_RS09405 b8c0a8249f7df23d9ce81066cdf8caf1 86 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 67 27.879 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CWR56_RS09405 b8c0a8249f7df23d9ce81066cdf8caf1 86 Gene3D G3DSA:2.30.30.100 5 76 2.5E-30 T 29-03-2018 CWR56_RS09405 b8c0a8249f7df23d9ce81066cdf8caf1 86 Pfam PF17209 Hfq protein 8 71 4.8E-30 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 Gene3D G3DSA:3.40.47.10 3 172 3.7E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 326 8.9E-134 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 SUPERFAMILY SSF53901 4 326 3.39E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 Gene3D G3DSA:3.40.47.10 173 327 1.3E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 185 1.8E-31 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 326 73.389 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR56_RS05370 9f8c83ac4683aef2bea84670ad00b7c3 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 326 2.0E-39 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Gene3D G3DSA:1.10.10.10 319 390 8.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Gene3D G3DSA:1.10.601.10 2 226 8.4E-84 T 29-03-2018 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 153 389 2.4E-124 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 390 34.049 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Pfam PF04542 Sigma-70 region 2 157 226 4.3E-23 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Pfam PF04539 Sigma-70 region 3 236 312 3.6E-32 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 350 376 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 181 194 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Pfam PF00140 Sigma-70 factor, region 1.2 119 151 7.8E-17 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 SUPERFAMILY SSF88659 230 304 2.88E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Pfam PF03979 Sigma-70 factor, region 1.1 16 81 3.6E-16 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 SUPERFAMILY SSF88946 118 227 2.88E-53 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Pfam PF04545 Sigma-70, region 4 325 378 1.7E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 SUPERFAMILY SSF88659 287 389 5.98E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 PRINTS PR00046 Major sigma-70 factor signature 205 213 1.3E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 PRINTS PR00046 Major sigma-70 factor signature 365 376 1.3E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 PRINTS PR00046 Major sigma-70 factor signature 181 194 1.3E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 PRINTS PR00046 Major sigma-70 factor signature 329 341 1.3E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 PRINTS PR00046 Major sigma-70 factor signature 350 365 1.3E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 Gene3D G3DSA:1.10.10.10 227 277 1.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06845 7b694619b62d63a70cfc641c229e8507 390 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 154 378 3.3E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 300 6.2E-52 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 SUPERFAMILY SSF52283 2 136 1.17E-35 T 29-03-2018 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 SUPERFAMILY SSF51735 104 301 8.65E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 Gene3D G3DSA:3.40.50.720 1 117 1.3E-22 T 29-03-2018 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 Gene3D G3DSA:3.40.50.720 118 303 1.8E-47 T 29-03-2018 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 332 2.2E-25 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 177 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CWR56_RS01880 1b72bceda337e6f7c7d36e70df825083 332 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 408 52.52 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 SUPERFAMILY SSF53383 3 408 1.39E-176 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 Pfam PF00464 Serine hydroxymethyltransferase 5 381 3.6E-174 T 29-03-2018 CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 Gene3D G3DSA:3.40.640.10 34 271 1.7E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 Gene3D G3DSA:3.90.1150.10 272 411 7.7E-57 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 PIRSF PIRSF000412 1 404 1.8E-171 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR56_RS13820 f554a6da7ce2940a55d3e94d6d7a7d0b 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR56_RS09265 d903113d85971d447cf278bee649c882 277 Pfam PF12833 Helix-turn-helix domain 188 265 6.0E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS09265 d903113d85971d447cf278bee649c882 277 Gene3D G3DSA:1.10.10.60 129 217 8.7E-9 T 29-03-2018 CWR56_RS09265 d903113d85971d447cf278bee649c882 277 Gene3D G3DSA:1.10.10.60 218 269 3.1E-8 T 29-03-2018 CWR56_RS09265 d903113d85971d447cf278bee649c882 277 SUPERFAMILY SSF46689 217 268 2.19E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09265 d903113d85971d447cf278bee649c882 277 SMART SM00342 181 264 3.6E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 SUPERFAMILY SSF47323 610 806 6.21E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Gene3D G3DSA:3.40.50.620 1 229 1.9E-78 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 SUPERFAMILY SSF52374 404 614 1.73E-152 T 29-03-2018 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 SUPERFAMILY SSF52374 3 226 1.73E-152 T 29-03-2018 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Gene3D G3DSA:1.10.730.10 595 742 6.6E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 515 537 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 548 558 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 476 494 1.8E-47 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 392 1.3E-63 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Gene3D G3DSA:3.90.740.10 230 391 8.3E-54 T 29-03-2018 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 805 22.955 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 806 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 405 606 1.8E-26 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 171 1.4E-28 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Pfam PF08264 Anticodon-binding domain of tRNA 644 767 9.1E-22 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 Gene3D G3DSA:3.40.50.620 392 594 1.7E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS12745 850483dce7e4150ed8a810955741fb7d 806 SUPERFAMILY SSF50677 223 407 2.75E-50 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWR56_RS02705 4047aeaf547e38dd0f49cfc3ba028e24 49 Pfam PF00563 EAL domain 1 33 2.0E-8 T 29-03-2018 IPR001633 EAL domain CWR56_RS02705 4047aeaf547e38dd0f49cfc3ba028e24 49 SUPERFAMILY SSF141868 1 45 6.8E-15 T 29-03-2018 IPR001633 EAL domain CWR56_RS02705 4047aeaf547e38dd0f49cfc3ba028e24 49 Gene3D G3DSA:3.20.20.450 1 49 5.9E-15 T 29-03-2018 IPR001633 EAL domain CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 Gene3D G3DSA:3.40.50.280 79 211 6.9E-36 T 29-03-2018 CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 Pfam PF02607 B12 binding domain 5 77 2.1E-10 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 Pfam PF02310 B12 binding domain 89 194 8.7E-24 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 Gene3D G3DSA:1.10.1240.10 2 78 1.9E-11 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 SUPERFAMILY SSF47644 1 77 9.42E-12 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 SMART SM01018 1 84 5.6E-18 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS08305 4e2110acdbde383021d0b2556deb1491 212 SUPERFAMILY SSF52242 72 209 1.7E-38 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS02535 f1ddd2131c98b55c8bc0a992537207d6 423 Gene3D G3DSA:1.10.101.10 333 416 6.4E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CWR56_RS02535 f1ddd2131c98b55c8bc0a992537207d6 423 Pfam PF01471 Putative peptidoglycan binding domain 346 403 2.1E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like CWR56_RS02535 f1ddd2131c98b55c8bc0a992537207d6 423 SUPERFAMILY SSF47090 333 407 9.73E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CWR56_RS02535 f1ddd2131c98b55c8bc0a992537207d6 423 Gene3D G3DSA:2.60.40.10 1 102 5.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 TIGRFAM TIGR00835 agcS: amino acid carrier protein 15 440 1.5E-156 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 PRINTS PR00175 Sodium/alanine symporter signature 211 230 7.9E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 PRINTS PR00175 Sodium/alanine symporter signature 409 429 7.9E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 PRINTS PR00175 Sodium/alanine symporter signature 350 372 7.9E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 PRINTS PR00175 Sodium/alanine symporter signature 89 111 7.9E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 PRINTS PR00175 Sodium/alanine symporter signature 183 201 7.9E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 PRINTS PR00175 Sodium/alanine symporter signature 306 324 7.9E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 89 104 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS11275 ce35e9589c5cc4e285515c6fa4f1f5c2 455 Pfam PF01235 Sodium:alanine symporter family 50 447 3.6E-149 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 Gene3D G3DSA:3.30.70.270 216 381 3.5E-29 T 29-03-2018 CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 368 1.8E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 SUPERFAMILY SSF55073 224 375 1.88E-23 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 SMART SM00267 208 374 2.5E-11 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 220 374 2.9E-18 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 SUPERFAMILY SSF141868 390 638 1.07E-74 T 29-03-2018 IPR001633 EAL domain CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 SMART SM00052 384 630 1.1E-72 T 29-03-2018 IPR001633 EAL domain CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 Pfam PF00563 EAL domain 392 625 8.6E-61 T 29-03-2018 IPR001633 EAL domain CWR56_RS03965 77d1466ba275396bfe7560bb3c1b2d3a 642 Gene3D G3DSA:3.20.20.450 382 641 4.8E-79 T 29-03-2018 IPR001633 EAL domain CWR56_RS07215 52f462ecad7d0aefe8ae98409aba67ab 181 Gene3D G3DSA:1.20.1260.10 25 123 4.3E-24 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS07215 52f462ecad7d0aefe8ae98409aba67ab 181 Pfam PF02915 Rubrerythrin 61 174 4.7E-14 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CWR56_RS07215 52f462ecad7d0aefe8ae98409aba67ab 181 SUPERFAMILY SSF57802 1 45 1.13E-11 T 29-03-2018 CWR56_RS07215 52f462ecad7d0aefe8ae98409aba67ab 181 SUPERFAMILY SSF47240 54 178 3.89E-32 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS07215 52f462ecad7d0aefe8ae98409aba67ab 181 Gene3D G3DSA:1.20.1260.10 124 181 1.8E-7 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS07215 52f462ecad7d0aefe8ae98409aba67ab 181 Gene3D G3DSA:2.20.28.10 1 24 1.1E-7 T 29-03-2018 CWR56_RS09175 e9ca2e1ef4795c9aea3757830cc93d9a 210 SUPERFAMILY SSF103088 76 202 1.03E-21 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS09175 e9ca2e1ef4795c9aea3757830cc93d9a 210 Pfam PF00691 OmpA family 86 192 2.6E-13 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS09175 e9ca2e1ef4795c9aea3757830cc93d9a 210 Gene3D G3DSA:3.30.1330.60 54 210 1.6E-28 T 29-03-2018 IPR006665 OmpA-like domain CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 Gene3D G3DSA:1.20.1560.10 13 352 4.9E-95 T 29-03-2018 CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 Gene3D G3DSA:3.40.50.300 353 609 1.5E-77 T 29-03-2018 CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 Pfam PF00664 ABC transporter transmembrane region 40 322 1.7E-57 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 SMART SM00382 393 565 3.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 SUPERFAMILY SSF52540 360 604 1.07E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 Pfam PF00005 ABC transporter 385 533 2.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 ProSitePatterns PS00211 ABC transporters family signature. 505 519 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS10675 f31e970a4c25d87bc1e05e99aa2954f8 610 SUPERFAMILY SSF90123 27 350 1.44E-84 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 287 31.257 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 Gene3D G3DSA:3.40.50.720 119 287 7.4E-31 T 29-03-2018 CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 2.1E-27 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 9 283 4.0E-66 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 SUPERFAMILY SSF51735 107 285 2.27E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 Gene3D G3DSA:3.40.50.10860 1 118 4.3E-42 T 29-03-2018 CWR56_RS13705 931d1f2681c593e1a2bd0b80b13e9ddc 287 SUPERFAMILY SSF53223 1 106 1.15E-33 T 29-03-2018 CWR56_RS17700 ff20cb18684782515385cbecd3b1be86 229 Pfam PF02223 Thymidylate kinase 11 193 4.3E-19 T 29-03-2018 CWR56_RS17700 ff20cb18684782515385cbecd3b1be86 229 Gene3D G3DSA:3.40.50.300 1 229 1.2E-30 T 29-03-2018 CWR56_RS17700 ff20cb18684782515385cbecd3b1be86 229 Hamap MF_00165 Thymidylate kinase [tmk]. 5 224 13.086 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR56_RS17700 ff20cb18684782515385cbecd3b1be86 229 SUPERFAMILY SSF52540 1 226 4.46E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12200 eb18e7fc48555a26385d8861fb65004d 337 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 7 189 1.2E-71 T 29-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS12200 eb18e7fc48555a26385d8861fb65004d 337 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 244 333 2.0E-43 T 29-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Pfam PF00874 PRD domain 297 385 5.6E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Gene3D G3DSA:3.40.930.10 526 670 2.3E-16 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Gene3D G3DSA:1.10.1790.10 286 390 2.0E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Gene3D G3DSA:3.40.50.2300 393 482 9.8E-12 T 29-03-2018 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 SUPERFAMILY SSF63520 295 390 1.7E-10 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Pfam PF05043 Mga helix-turn-helix domain 83 147 1.5E-5 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 SUPERFAMILY SSF55804 527 670 8.37E-22 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Gene3D G3DSA:1.10.10.10 1 65 1.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Gene3D G3DSA:1.10.10.10 80 143 7.6E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01025 a2c5426d55b2e1ea2b217806cb3f6167 676 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 545 664 8.5E-16 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 SUPERFAMILY SSF52009 747 854 2.09E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 Pfam PF00391 PEP-utilising enzyme, mobile domain 778 849 2.2E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 SUPERFAMILY SSF56059 14 341 1.53E-92 T 29-03-2018 CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 Gene3D G3DSA:3.30.470.20 183 329 8.3E-42 T 29-03-2018 CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 314 4.3E-108 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 Gene3D G3DSA:3.30.1490.20 9 181 2.0E-50 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS11035 4b5fa5884ad190289bc82145831a6bf8 855 Gene3D G3DSA:3.50.30.10 742 853 3.1E-35 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Gene3D G3DSA:3.30.450.20 159 259 0.0065 T 29-03-2018 CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 403 565 1.3E-40 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 SUPERFAMILY SSF55785 29 143 1.69E-8 T 29-03-2018 IPR000014 PAS domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Gene3D G3DSA:3.30.450.20 746 807 4.2E-4 T 29-03-2018 CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 SUPERFAMILY SSF55073 412 568 5.89E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 SMART SM00267 396 566 9.2E-47 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Pfam PF13426 PAS domain 39 133 1.1E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Pfam PF13426 PAS domain 296 394 5.1E-4 T 29-03-2018 IPR000014 PAS domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Pfam PF13426 PAS domain 175 219 0.097 T 29-03-2018 IPR000014 PAS domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Gene3D G3DSA:3.30.70.270 401 567 1.8E-49 T 29-03-2018 CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Gene3D G3DSA:3.30.450.20 260 400 2.1E-10 T 29-03-2018 CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Gene3D G3DSA:3.30.450.20 20 158 6.1E-12 T 29-03-2018 CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Pfam PF00990 Diguanylate cyclase, GGDEF domain 409 562 4.4E-42 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 SUPERFAMILY SSF55785 264 394 1.13E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 SUPERFAMILY SSF55781 601 756 6.76E-13 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS18105 d52e03f3b5d42c7c506f9b6424bdde94 835 Gene3D G3DSA:3.30.450.40 589 745 7.7E-14 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS05120 a2179b90146639371fcc39001c14a97e 184 Gene3D G3DSA:1.10.530.10 28 178 1.9E-38 T 29-03-2018 CWR56_RS05120 a2179b90146639371fcc39001c14a97e 184 Pfam PF01464 Transglycosylase SLT domain 38 146 3.9E-30 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CWR56_RS05120 a2179b90146639371fcc39001c14a97e 184 SUPERFAMILY SSF53955 34 180 9.7E-40 T 29-03-2018 IPR023346 Lysozyme-like domain CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 Gene3D G3DSA:3.40.50.720 5 246 1.0E-41 T 29-03-2018 CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 Pfam PF00106 short chain dehydrogenase 5 189 4.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 SUPERFAMILY SSF51735 4 253 9.32E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.5E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.5E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.5E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS03315 0a80a0106e400d883d83e059fd020834 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Pfam PF00874 PRD domain 324 413 6.1E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Pfam PF00874 PRD domain 208 296 5.3E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Pfam PF05043 Mga helix-turn-helix domain 93 164 1.4E-10 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Gene3D G3DSA:1.10.1790.10 300 417 5.9E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Gene3D G3DSA:3.40.50.2300 418 506 2.8E-20 T 29-03-2018 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Pfam PF08279 HTH domain 5 61 2.8E-6 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 SUPERFAMILY SSF63520 324 417 6.02E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 SUPERFAMILY SSF52794 419 503 3.71E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 422 500 1.3E-5 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Gene3D G3DSA:1.10.1790.10 198 299 1.1E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 SUPERFAMILY SSF63520 190 297 3.66E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Gene3D G3DSA:1.10.10.10 86 155 5.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15655 6de1b194e6eec5b1aecf65bf53ef8e7b 635 Gene3D G3DSA:1.10.10.10 2 67 4.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 SUPERFAMILY SSF55785 205 259 1.07E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 Pfam PF00158 Sigma-54 interaction domain 333 500 2.3E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 541 550 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 419 434 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 SMART SM00382 352 500 3.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 SUPERFAMILY SSF52540 332 571 3.62E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 Gene3D G3DSA:3.40.50.300 325 504 1.6E-26 T 29-03-2018 CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 Gene3D G3DSA:3.30.450.20 184 303 7.9E-7 T 29-03-2018 CWR56_RS14550 93cc318b0720bbba651208b987623c08 681 Gene3D G3DSA:1.10.8.60 505 578 3.1E-17 T 29-03-2018 CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 219 230 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 Gene3D G3DSA:3.40.50.360 1 142 7.0E-17 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 SUPERFAMILY SSF52218 1 144 5.64E-20 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 Gene3D G3DSA:3.30.70.20 203 242 5.1E-10 T 29-03-2018 CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 Pfam PF12724 Flavodoxin domain 1 108 5.9E-11 T 29-03-2018 IPR026816 Flavodoxin domain CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 Pfam PF13187 4Fe-4S dicluster domain 190 234 2.4E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 Gene3D G3DSA:3.30.70.20 168 202 2.2E-7 T 29-03-2018 CWR56_RS15595 c7ed6695ef33add4de9c54a80707366b 249 SUPERFAMILY SSF54862 186 242 7.53E-15 T 29-03-2018 CWR56_RS11620 c38be744162d7fec210e235ed141e7ac 372 Gene3D G3DSA:1.20.1090.10 173 372 1.4E-43 T 29-03-2018 CWR56_RS11620 c38be744162d7fec210e235ed141e7ac 372 SUPERFAMILY SSF56796 17 371 2.09E-73 T 29-03-2018 CWR56_RS11620 c38be744162d7fec210e235ed141e7ac 372 Gene3D G3DSA:3.40.50.1970 15 171 5.8E-24 T 29-03-2018 CWR56_RS11620 c38be744162d7fec210e235ed141e7ac 372 Pfam PF00465 Iron-containing alcohol dehydrogenase 14 364 1.7E-73 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS05615 23b9b5caa4b941b7e9abe8bc6bd83af8 415 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR56_RS05615 23b9b5caa4b941b7e9abe8bc6bd83af8 415 Pfam PF01136 Peptidase family U32 79 310 5.3E-103 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR56_RS05615 23b9b5caa4b941b7e9abe8bc6bd83af8 415 Pfam PF16325 Peptidase family U32 C-terminal domain 324 406 5.4E-28 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal CWR56_RS05615 23b9b5caa4b941b7e9abe8bc6bd83af8 415 Gene3D G3DSA:3.20.20.70 5 253 2.4E-6 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS03825 a2e48e91ae260ff9aa065e91c994db05 335 Gene3D G3DSA:2.40.10.10 252 330 3.5E-4 T 29-03-2018 CWR56_RS03825 a2e48e91ae260ff9aa065e91c994db05 335 SUPERFAMILY SSF50156 75 137 2.0E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS03825 a2e48e91ae260ff9aa065e91c994db05 335 Pfam PF05580 SpoIVB peptidase S55 144 335 3.1E-58 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB CWR56_RS03825 a2e48e91ae260ff9aa065e91c994db05 335 Gene3D G3DSA:2.30.42.10 68 161 4.1E-7 T 29-03-2018 CWR56_RS03825 a2e48e91ae260ff9aa065e91c994db05 335 SUPERFAMILY SSF50494 231 334 3.71E-5 T 29-03-2018 IPR009003 Peptidase S1, PA clan CWR56_RS02185 bf63fb3c3b26ac8b9eacf2f3660b0b5f 208 SUPERFAMILY SSF52141 75 203 1.18E-7 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS02185 bf63fb3c3b26ac8b9eacf2f3660b0b5f 208 Pfam PF03167 Uracil DNA glycosylase superfamily 71 159 3.2E-9 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS02185 bf63fb3c3b26ac8b9eacf2f3660b0b5f 208 Gene3D G3DSA:3.40.470.10 62 208 5.9E-10 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 Gene3D G3DSA:3.20.20.150 2 439 1.7E-111 T 29-03-2018 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 Hamap MF_00455 Xylose isomerase [xylA]. 11 436 54.402 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 SUPERFAMILY SSF51658 4 438 7.02E-170 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 5 436 8.2E-223 T 29-03-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 Pfam PF01261 Xylose isomerase-like TIM barrel 88 285 8.3E-9 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 156 175 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 133 153 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 180 201 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 271 298 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 300 311 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 333 344 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 229 253 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 92 114 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS15275 fdc17808d16f0d0930716a37b4052576 445 PRINTS PR00688 Xylose isomerase signature 207 226 2.6E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Gene3D G3DSA:3.40.50.300 2 299 5.8E-55 T 29-03-2018 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 SUPERFAMILY SSF52540 314 538 7.76E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Pfam PF16326 ABC transporter C-terminal domain 564 635 5.8E-12 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Pfam PF00005 ABC transporter 349 478 3.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Pfam PF00005 ABC transporter 19 195 2.3E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 SMART SM00382 28 242 6.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 SMART SM00382 357 523 2.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Gene3D G3DSA:1.20.58.410 562 636 1.6E-5 T 29-03-2018 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Pfam PF12848 ABC transporter 234 322 2.3E-20 T 29-03-2018 IPR032781 ABC-transporter extension domain CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 Gene3D G3DSA:3.40.50.300 300 559 1.1E-57 T 29-03-2018 CWR56_RS00835 68144c063e1edbfde7a608bab90044fe 637 SUPERFAMILY SSF52540 4 249 1.46E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18015 9ab7f2060b26bb601a2ddce64dd31c8b 394 PIRSF PIRSF039004 1 394 4.7E-138 T 29-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CWR56_RS18015 9ab7f2060b26bb601a2ddce64dd31c8b 394 Pfam PF01979 Amidohydrolase family 63 352 1.0E-9 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS18015 9ab7f2060b26bb601a2ddce64dd31c8b 394 Gene3D G3DSA:3.20.20.140 78 329 7.4E-24 T 29-03-2018 CWR56_RS18015 9ab7f2060b26bb601a2ddce64dd31c8b 394 SUPERFAMILY SSF51556 67 330 4.9E-51 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS18015 9ab7f2060b26bb601a2ddce64dd31c8b 394 Gene3D G3DSA:2.30.40.10 1 77 1.4E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS18015 9ab7f2060b26bb601a2ddce64dd31c8b 394 SUPERFAMILY SSF51338 1 74 3.3E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 SMART SM00922 140 236 7.6E-22 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 Pfam PF13378 Enolase C-terminal domain-like 143 354 2.9E-46 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 SUPERFAMILY SSF51604 111 354 1.01E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 123 8.6E-20 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 Gene3D G3DSA:3.30.390.10 1 114 5.7E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 SUPERFAMILY SSF54826 1 124 5.89E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR56_RS06490 a5d9b889992e9ab5e101cb50d43a1d04 355 Gene3D G3DSA:3.20.20.120 115 354 2.7E-58 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CWR56_RS02480 c751b7eea8c8d3c00aa58418391cf8e9 146 SMART SM00260 5 142 3.9E-24 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02480 c751b7eea8c8d3c00aa58418391cf8e9 146 Gene3D G3DSA:2.30.30.40 85 136 4.7E-8 T 29-03-2018 CWR56_RS02480 c751b7eea8c8d3c00aa58418391cf8e9 146 Pfam PF01584 CheW-like domain 9 142 2.1E-28 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS02480 c751b7eea8c8d3c00aa58418391cf8e9 146 Gene3D G3DSA:2.40.50.180 26 84 5.2E-20 T 29-03-2018 CWR56_RS02480 c751b7eea8c8d3c00aa58418391cf8e9 146 SUPERFAMILY SSF50341 8 142 3.79E-32 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 PIRSF PIRSF005243 1 397 1.2E-125 T 29-03-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 Pfam PF00258 Flavodoxin 257 386 2.1E-8 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 Pfam PF00753 Metallo-beta-lactamase superfamily 37 167 7.0E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 Gene3D G3DSA:3.40.50.360 253 397 5.1E-19 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 SUPERFAMILY SSF52218 253 397 6.76E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 Gene3D G3DSA:3.60.15.10 1 252 2.4E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 SUPERFAMILY SSF56281 11 288 7.86E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05255 de2373efa127a9fec6bcce7cf60fb0f2 397 SMART SM00849 35 224 2.9E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 284 1.4E-67 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 SUPERFAMILY SSF161111 4 206 1.83E-50 T 29-03-2018 CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 Gene3D G3DSA:3.30.70.1350 206 287 1.4E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 284 1.9E-21 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 Pfam PF01545 Cation efflux family 11 205 1.1E-40 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 SUPERFAMILY SSF160240 211 285 6.8E-19 T 29-03-2018 CWR56_RS04435 049992a36b9d86f0a96642230bb0888d 288 Gene3D G3DSA:1.20.1510.10 6 205 3.0E-38 T 29-03-2018 CWR56_RS18355 8fdf2f95dbccb212f656c7df8ee49cd4 61 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 59 8.7E-27 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CWR56_RS18355 8fdf2f95dbccb212f656c7df8ee49cd4 61 PIRSF PIRSF037263 1 61 1.3E-26 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 278 632 5.9E-149 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Pfam PF00266 Aminotransferase class-V 308 579 1.1E-26 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 273 636 176.537 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Gene3D G3DSA:3.40.50.1000 99 267 4.8E-26 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Gene3D G3DSA:3.40.640.10 289 526 5.7E-24 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 SUPERFAMILY SSF53383 275 635 4.71E-83 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 8 259 3.0E-110 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 290 114.888 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 201 1.1E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Gene3D G3DSA:3.90.1150.10 527 636 1.2E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Gene3D G3DSA:1.10.150.240 27 98 4.2E-32 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 SUPERFAMILY SSF56784 8 259 6.46E-58 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 274 633 3.3E-172 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CWR56_RS14480 966e6784cf2ea7ed12c4d9d6bd7438ff 636 Pfam PF13419 Haloacid dehalogenase-like hydrolase 29 207 4.4E-13 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS13055 21cd3d50e8bc9c5220c6d3f5424098b6 233 Pfam PF04298 Putative neutral zinc metallopeptidase 14 228 4.5E-93 T 29-03-2018 IPR007395 Putative neutral zinc metallopeptidase CWR56_RS14445 da37e4ef329f49c79faae2f1340edc12 195 Pfam PF02915 Rubrerythrin 10 138 8.9E-23 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CWR56_RS14445 da37e4ef329f49c79faae2f1340edc12 195 Gene3D G3DSA:1.20.1260.10 2 80 8.7E-14 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS14445 da37e4ef329f49c79faae2f1340edc12 195 SUPERFAMILY SSF57802 151 188 2.9E-10 T 29-03-2018 CWR56_RS14445 da37e4ef329f49c79faae2f1340edc12 195 SUPERFAMILY SSF47240 3 148 2.9E-32 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS14445 da37e4ef329f49c79faae2f1340edc12 195 Gene3D G3DSA:1.20.1260.10 81 156 3.5E-11 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS14445 da37e4ef329f49c79faae2f1340edc12 195 Gene3D G3DSA:2.20.28.10 157 188 2.1E-6 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 421 465 2.0E-14 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 213 263 4.4E-14 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 466 521 4.2E-16 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 361 420 3.4E-12 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 36 118 9.4E-15 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 173 212 1.6E-7 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 264 315 1.1E-14 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 316 360 3.5E-14 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Gene3D G3DSA:2.160.20.50 119 172 1.7E-13 T 29-03-2018 CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 516 688 9.0E-71 T 29-03-2018 IPR021210 Exosporium BclB, C-terminal CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Pfam PF01391 Collagen triple helix repeat (20 copies) 368 423 2.1E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Pfam PF01391 Collagen triple helix repeat (20 copies) 307 364 9.5E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CWR56_RS16770 95f43769fae33006b4b2404400525da5 688 Pfam PF01391 Collagen triple helix repeat (20 copies) 459 517 1.3E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CWR56_RS11530 7efdf2da6fb35641c35f4e84abd86d62 148 PIRSF PIRSF005384 1 147 1.9E-60 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS11530 7efdf2da6fb35641c35f4e84abd86d62 148 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.7E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS11530 7efdf2da6fb35641c35f4e84abd86d62 148 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 1.3E-59 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CWR56_RS11530 7efdf2da6fb35641c35f4e84abd86d62 148 Gene3D G3DSA:3.40.1400.10 1 148 1.1E-65 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS11530 7efdf2da6fb35641c35f4e84abd86d62 148 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 5.3E-59 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS11530 7efdf2da6fb35641c35f4e84abd86d62 148 SUPERFAMILY SSF89623 1 144 1.96E-58 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS11975 30185c472d430855eebd4990d69cc2b7 252 Gene3D G3DSA:1.10.10.60 1 31 2.0E-6 T 29-03-2018 CWR56_RS11975 30185c472d430855eebd4990d69cc2b7 252 Pfam PF12844 Helix-turn-helix domain 10 72 8.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11975 30185c472d430855eebd4990d69cc2b7 252 SUPERFAMILY SSF47413 6 72 5.63E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS11975 30185c472d430855eebd4990d69cc2b7 252 Gene3D G3DSA:3.30.1190.10 32 107 4.5E-14 T 29-03-2018 CWR56_RS11975 30185c472d430855eebd4990d69cc2b7 252 SMART SM00530 12 67 3.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 365 8.5E-156 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 Gene3D G3DSA:3.10.20.30 265 364 3.6E-44 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 1.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 68 83 1.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 103 1.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 1.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 365 44.469 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 Pfam PF06071 Protein of unknown function (DUF933) 281 364 1.2E-37 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 SUPERFAMILY SSF52540 1 303 1.5E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 SUPERFAMILY SSF81271 281 362 1.63E-33 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 PIRSF PIRSF006641 1 365 1.1E-159 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 Pfam PF01926 50S ribosome-binding GTPase 3 113 3.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 Gene3D G3DSA:1.10.150.300 108 197 1.5E-28 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CWR56_RS13470 2bd8e705cf2a0367874bd106cfd03e69 365 Gene3D G3DSA:3.40.50.300 1 78 3.3E-8 T 29-03-2018 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 SUPERFAMILY SSF48452 164 268 1.33E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 Pfam PF00515 Tetratricopeptide repeat 228 260 1.2E-9 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 Gene3D G3DSA:1.25.40.10 144 224 2.1E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 Gene3D G3DSA:1.25.40.10 225 270 4.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 SMART SM00028 227 260 1.2E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 SMART SM00028 185 218 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 Pfam PF13181 Tetratricopeptide repeat 187 213 0.0072 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS05635 ea251eac9ac81180fa9cc31684e71234 273 Gene3D G3DSA:3.10.450.100 26 143 6.5E-7 T 29-03-2018 CWR56_RS12960 56b384e43285dffba29a5acc8cb055f2 158 Pfam PF04754 Putative transposase, YhgA-like 14 144 1.5E-13 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 SUPERFAMILY SSF51182 54 179 2.3E-30 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 SMART SM00530 6 61 3.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 Gene3D G3DSA:2.60.120.10 80 179 3.8E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 Pfam PF12844 Helix-turn-helix domain 4 66 4.7E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 Gene3D G3DSA:1.10.260.40 1 79 1.6E-19 T 29-03-2018 CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 Pfam PF07883 Cupin domain 106 173 4.5E-17 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS04665 38114f4e8252689d6c6132d19320b542 179 SUPERFAMILY SSF47413 1 68 2.51E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS07595 d2efd795a26e2e291b88446b05a336aa 264 Pfam PF08543 Phosphomethylpyrimidine kinase 15 258 1.0E-96 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CWR56_RS07595 d2efd795a26e2e291b88446b05a336aa 264 Gene3D G3DSA:3.40.1190.20 4 252 9.7E-57 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS07595 d2efd795a26e2e291b88446b05a336aa 264 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 9 260 3.4E-103 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07595 d2efd795a26e2e291b88446b05a336aa 264 SUPERFAMILY SSF53613 9 262 1.17E-80 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 Pfam PF00239 Resolvase, N terminal domain 4 140 7.5E-33 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 Gene3D G3DSA:3.40.50.1390 2 113 3.1E-29 T 29-03-2018 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 Gene3D G3DSA:1.20.5.40 114 129 1.3E-12 T 29-03-2018 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 SUPERFAMILY SSF53041 4 140 6.28E-33 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 Gene3D G3DSA:1.10.10.60 130 188 7.1E-5 T 29-03-2018 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 ProSitePatterns PS00398 Site-specific recombinases signature 2. 62 74 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 SMART SM00857 4 143 1.0E-39 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS17870 0e5f5db02c9651fb6263ca0ba8c1a3ee 189 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR56_RS18175 0f3ffd62cf23e5f1fc4b5175e31751cc 462 Pfam PF08309 LVIVD repeat 183 197 1.8 T 29-03-2018 IPR013211 LVIVD CWR56_RS18175 0f3ffd62cf23e5f1fc4b5175e31751cc 462 Pfam PF08309 LVIVD repeat 317 334 0.35 T 29-03-2018 IPR013211 LVIVD CWR56_RS18175 0f3ffd62cf23e5f1fc4b5175e31751cc 462 Gene3D G3DSA:2.115.10.20 17 462 0.0012 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR56_RS11320 1fe3c599c6de0fddeb3d810f2d61a117 122 Pfam PF03965 Penicillinase repressor 6 119 3.7E-21 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS11320 1fe3c599c6de0fddeb3d810f2d61a117 122 Gene3D G3DSA:1.10.4040.10 71 120 2.2E-12 T 29-03-2018 CWR56_RS11320 1fe3c599c6de0fddeb3d810f2d61a117 122 Gene3D G3DSA:1.10.10.10 5 70 7.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11320 1fe3c599c6de0fddeb3d810f2d61a117 122 PIRSF PIRSF019455 1 122 4.1E-28 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS11320 1fe3c599c6de0fddeb3d810f2d61a117 122 SUPERFAMILY SSF46785 2 121 1.78E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12800 524be200f293c6adb315aebc2f4934bd 380 SUPERFAMILY SSF53383 2 364 1.28E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12800 524be200f293c6adb315aebc2f4934bd 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 182 202 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWR56_RS12800 524be200f293c6adb315aebc2f4934bd 380 Gene3D G3DSA:3.40.640.10 14 265 1.4E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS12800 524be200f293c6adb315aebc2f4934bd 380 PIRSF PIRSF000524 1 376 1.0E-89 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CWR56_RS12800 524be200f293c6adb315aebc2f4934bd 380 Pfam PF00266 Aminotransferase class-V 34 302 1.3E-27 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS12800 524be200f293c6adb315aebc2f4934bd 380 Gene3D G3DSA:3.90.1150.10 266 363 5.8E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 496 619 1.8E-47 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 Gene3D G3DSA:2.70.70.10 482 642 2.5E-53 T 29-03-2018 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 Pfam PF02378 Phosphotransferase system, EIIC 108 405 1.5E-30 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 SUPERFAMILY SSF51261 489 640 1.27E-50 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 Pfam PF00367 phosphotransferase system, EIIB 9 42 1.7E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 558 570 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 SUPERFAMILY SSF55604 7 82 5.23E-23 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 496 616 1.3E-41 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 640 3.0E-216 T 29-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CWR56_RS15615 c57c1e43cf46978162296e48071e7c6d 642 Gene3D G3DSA:3.30.1360.60 5 81 1.5E-27 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 Gene3D G3DSA:3.30.565.10 308 462 1.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 SMART SM00387 351 462 2.9E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 460 3.6E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 SMART SM00388 240 305 1.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 305 1.5E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 9.1E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 9.1E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 9.1E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 Gene3D G3DSA:1.10.287.130 230 301 3.1E-11 T 29-03-2018 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 SUPERFAMILY SSF47384 225 305 4.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS06285 8edd412b44f6371eeca808a39bd3411d 462 SUPERFAMILY SSF55874 308 461 3.93E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 76 4.0E-17 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 PRINTS PR00124 ATP synthase C subunit signature 33 48 2.9E-18 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 PRINTS PR00124 ATP synthase C subunit signature 12 31 2.9E-18 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 PRINTS PR00124 ATP synthase C subunit signature 50 75 2.9E-18 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 Gene3D G3DSA:1.20.20.10 5 77 4.0E-20 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 75 15.382 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 Pfam PF00137 ATP synthase subunit C 12 74 7.9E-16 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS17310 c4fcdce92f0bba541e4c93f72143dce4 86 SUPERFAMILY SSF81333 5 78 8.76E-18 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 SUPERFAMILY SSF88659 109 181 7.85E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 SUPERFAMILY SSF88946 9 105 1.31E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 Pfam PF04539 Sigma-70 region 3 119 168 8.4E-7 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 253 2.3E-97 T 29-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 252 2.2E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 SUPERFAMILY SSF88659 187 253 2.43E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 PIRSF PIRSF000770 1 254 1.3E-33 T 29-03-2018 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 Gene3D G3DSA:1.10.10.10 182 254 1.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 Gene3D G3DSA:1.10.601.10 4 105 4.8E-32 T 29-03-2018 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 PRINTS PR00046 Major sigma-70 factor signature 223 238 1.0E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 PRINTS PR00046 Major sigma-70 factor signature 85 93 1.0E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 PRINTS PR00046 Major sigma-70 factor signature 206 218 1.0E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 PRINTS PR00046 Major sigma-70 factor signature 238 249 1.0E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 PRINTS PR00046 Major sigma-70 factor signature 61 74 1.0E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 223 249 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 31 253 1.4E-79 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 Gene3D G3DSA:1.10.10.10 106 158 5.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 Pfam PF04545 Sigma-70, region 4 203 251 1.1E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03750 4b6dbd9ec6d6d62a5e1fbcac9ccacd67 254 Pfam PF04542 Sigma-70 region 2 37 103 1.9E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 Pfam PF07687 Peptidase dimerisation domain 185 275 2.4E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 Gene3D G3DSA:3.40.630.10 355 447 1.5E-12 T 29-03-2018 CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 Gene3D G3DSA:3.40.630.10 6 302 8.9E-44 T 29-03-2018 CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 SUPERFAMILY SSF55031 185 292 3.4E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 PIRSF PIRSF037227 3 459 5.6E-153 T 29-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 SUPERFAMILY SSF53187 296 325 1.52E-58 T 29-03-2018 CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 SUPERFAMILY SSF53187 7 197 1.52E-58 T 29-03-2018 CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 SUPERFAMILY SSF53187 365 430 1.52E-58 T 29-03-2018 CWR56_RS15550 705ba5124ad5ce6e73ea3a12ddf07ee1 459 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 394 1.1E-71 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS07205 847b4d138263bf47df6533d1e5b0245a 293 SUPERFAMILY SSF88713 69 290 5.44E-45 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS07205 847b4d138263bf47df6533d1e5b0245a 293 Gene3D G3DSA:3.20.20.370 64 292 6.3E-41 T 29-03-2018 CWR56_RS07205 847b4d138263bf47df6533d1e5b0245a 293 Pfam PF01522 Polysaccharide deacetylase 90 206 1.7E-21 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 Gene3D G3DSA:1.10.10.10 6 62 2.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 52 4.8E-16 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 Pfam PF12727 PBP superfamily domain 93 282 1.7E-62 T 29-03-2018 IPR024370 PBP domain CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 Gene3D G3DSA:3.40.190.10 160 269 1.5E-9 T 29-03-2018 CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 SUPERFAMILY SSF53850 91 297 2.54E-21 T 29-03-2018 CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 SUPERFAMILY SSF46955 7 55 1.04E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS04265 3b336f9ad939d7414c8630b260de3460 309 Pfam PF12728 Helix-turn-helix domain 7 55 8.8E-17 T 29-03-2018 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 SUPERFAMILY SSF55874 301 465 6.68E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 SMART SM00387 358 467 4.9E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 Gene3D G3DSA:3.30.565.10 307 467 4.0E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 SUPERFAMILY SSF47384 227 312 2.75E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 Gene3D G3DSA:1.10.287.130 235 306 4.5E-14 T 29-03-2018 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 307 6.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 SMART SM00388 244 312 1.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07980 a2c40ef426f22ee6abe9ac1401726cf6 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 466 9.5E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16385 752f798b47c7288346dbdf2aa2326ffd 478 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 170 405 1.9E-55 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CWR56_RS16385 752f798b47c7288346dbdf2aa2326ffd 478 SUPERFAMILY SSF53920 136 439 1.83E-64 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS16385 752f798b47c7288346dbdf2aa2326ffd 478 Gene3D G3DSA:3.40.50.1780 238 353 8.2E-19 T 29-03-2018 CWR56_RS16385 752f798b47c7288346dbdf2aa2326ffd 478 Gene3D G3DSA:3.40.50.1780 122 237 2.7E-19 T 29-03-2018 CWR56_RS04855 fb824f962069bb14f16680028d778780 336 Gene3D G3DSA:3.40.50.620 1 197 7.5E-59 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS04855 fb824f962069bb14f16680028d778780 336 SUPERFAMILY SSF52402 3 197 4.6E-54 T 29-03-2018 CWR56_RS04855 fb824f962069bb14f16680028d778780 336 Gene3D G3DSA:3.40.50.1220 200 330 1.1E-55 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS04855 fb824f962069bb14f16680028d778780 336 SMART SM00893 4 199 9.3E-51 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS04855 fb824f962069bb14f16680028d778780 336 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 204 287 1.2E-34 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CWR56_RS04855 fb824f962069bb14f16680028d778780 336 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 268 294 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CWR56_RS04855 fb824f962069bb14f16680028d778780 336 Pfam PF01012 Electron transfer flavoprotein domain 4 182 1.7E-50 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS04855 fb824f962069bb14f16680028d778780 336 SUPERFAMILY SSF52467 202 324 1.17E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS04855 fb824f962069bb14f16680028d778780 336 PIRSF PIRSF000089 1 329 2.9E-111 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CWR56_RS16475 77e6d76cd2b61615d57d3a851aaa6fa4 268 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 5 268 2.9E-105 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 Gene3D G3DSA:3.90.180.10 1 164 1.1E-48 T 29-03-2018 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 Pfam PF00107 Zinc-binding dehydrogenase 175 305 1.0E-24 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 SMART SM00829 10 341 7.5E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 4.1E-34 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 SUPERFAMILY SSF50129 1 172 3.96E-51 T 29-03-2018 IPR011032 GroES-like CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 Gene3D G3DSA:3.40.50.720 165 289 2.4E-25 T 29-03-2018 CWR56_RS11545 27eec97f295d88d284e57fb76e006232 343 SUPERFAMILY SSF51735 138 309 9.86E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS06430 39d571027ac94a362208ad18f42d847d 69 SMART SM00530 14 68 2.6E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06430 39d571027ac94a362208ad18f42d847d 69 Pfam PF01381 Helix-turn-helix 16 48 4.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06430 39d571027ac94a362208ad18f42d847d 69 Gene3D G3DSA:1.10.260.40 4 67 1.5E-10 T 29-03-2018 CWR56_RS06430 39d571027ac94a362208ad18f42d847d 69 SUPERFAMILY SSF47413 8 64 9.01E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 SUPERFAMILY SSF52172 2 177 4.13E-35 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 SMART SM00448 2 112 5.4E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 Pfam PF00072 Response regulator receiver domain 4 112 4.3E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 Gene3D G3DSA:1.10.10.10 127 227 1.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 1.4E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 SMART SM00862 146 221 3.9E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS09330 08883e87e9e1b6d5b24938a38455d4e5 228 Gene3D G3DSA:3.40.50.2300 1 126 1.9E-28 T 29-03-2018 CWR56_RS08680 5d5e9085ddc3a2ec0a58edd43ee85583 296 Pfam PF00753 Metallo-beta-lactamase superfamily 18 207 1.3E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS08680 5d5e9085ddc3a2ec0a58edd43ee85583 296 Gene3D G3DSA:3.60.15.10 1 261 4.3E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS08680 5d5e9085ddc3a2ec0a58edd43ee85583 296 SUPERFAMILY SSF56281 4 288 2.17E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS08680 5d5e9085ddc3a2ec0a58edd43ee85583 296 SMART SM00849 19 207 1.7E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 Pfam PF02926 THUMP domain 42 166 6.4E-13 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 375 2.1E-115 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 SUPERFAMILY SSF143437 3 175 2.96E-49 T 29-03-2018 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 Gene3D G3DSA:3.30.70.1510 5 81 1.3E-26 T 29-03-2018 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 Gene3D G3DSA:3.30.2300.10 86 165 2.4E-16 T 29-03-2018 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 Gene3D G3DSA:3.40.50.620 177 391 2.8E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 391 149.82 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 372 2.5E-70 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 SUPERFAMILY SSF52402 176 384 5.07E-51 T 29-03-2018 CWR56_RS03660 fb7e97cddaf4d4c7c71ac828b89efd57 391 SMART SM00981 74 167 1.1E-19 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 SUPERFAMILY SSF46785 150 221 3.63E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 208 5.5E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 177 193 5.5E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 Gene3D G3DSA:2.60.120.10 5 147 1.5E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 Gene3D G3DSA:1.10.10.10 148 224 1.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 SUPERFAMILY SSF51206 9 144 9.82E-30 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 SMART SM00100 14 132 5.6E-14 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 Pfam PF13545 Crp-like helix-turn-helix domain 153 217 7.5E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 SMART SM00419 171 219 9.2E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS10810 98b7924884922508e7a64d24b811c4ca 229 Pfam PF00027 Cyclic nucleotide-binding domain 33 120 1.4E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS09760 30281a41343359651e5756e24ef5c7b2 120 SUPERFAMILY SSF47413 5 70 1.38E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS09760 30281a41343359651e5756e24ef5c7b2 120 SMART SM00530 11 66 1.1E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09760 30281a41343359651e5756e24ef5c7b2 120 Gene3D G3DSA:1.10.3100.10 1 120 5.7E-22 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS09760 30281a41343359651e5756e24ef5c7b2 120 Pfam PF01381 Helix-turn-helix 12 65 6.8E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS18220 3e6f9873e1dfcaeeb926c77d30180014 105 Gene3D G3DSA:1.20.58.80 3 101 2.0E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS18220 3e6f9873e1dfcaeeb926c77d30180014 105 SUPERFAMILY SSF46973 2 99 2.88E-34 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS18220 3e6f9873e1dfcaeeb926c77d30180014 105 PIRSF PIRSF000699 1 105 5.1E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS18220 3e6f9873e1dfcaeeb926c77d30180014 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 99 5.3E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 SUPERFAMILY SSF46689 6 54 3.58E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 Gene3D G3DSA:3.20.80.10 146 303 1.8E-20 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 1.0E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 1.0E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 Gene3D G3DSA:1.10.10.60 58 117 6.2E-12 T 29-03-2018 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 Pfam PF14526 Integron-associated effector binding protein 176 300 1.2E-12 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 SMART SM00342 21 104 2.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 SUPERFAMILY SSF55136 198 300 6.28E-8 T 29-03-2018 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 Pfam PF12833 Helix-turn-helix domain 27 105 2.4E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 Gene3D G3DSA:1.10.10.60 3 57 1.9E-10 T 29-03-2018 CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 SMART SM00871 138 302 4.2E-7 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS10985 d0b630e5d81178de27ff1e1aea7982a6 303 SUPERFAMILY SSF46689 57 109 2.2E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 35.787 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 Gene3D G3DSA:3.40.50.1470 1 186 5.0E-74 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 SUPERFAMILY SSF53178 1 185 1.27E-67 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 185 3.1E-65 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR56_RS17465 9c014f860ebb954f06d296a75e18cf96 186 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.2E-61 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 Gene3D G3DSA:2.40.30.10 280 361 7.7E-25 T 29-03-2018 CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 5 357 2.9E-116 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 5 358 42.097 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 Gene3D G3DSA:3.40.50.620 3 215 1.1E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 SUPERFAMILY SSF52402 3 249 7.28E-60 T 29-03-2018 CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 Pfam PF03054 tRNA methyl transferase 5 357 4.5E-128 T 29-03-2018 CWR56_RS05935 3b989c4e44114468d25ceb0fb2f1b5e0 361 Gene3D G3DSA:2.30.30.280 220 279 5.2E-19 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 SUPERFAMILY SSF46894 133 233 1.64E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 Gene3D G3DSA:1.10.10.10 140 237 6.9E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 233 7.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 SUPERFAMILY SSF52172 3 124 2.13E-39 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 SMART SM00862 157 233 6.8E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 SMART SM00448 3 113 3.1E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 Pfam PF00072 Response regulator receiver domain 5 113 3.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS11510 9bd3a7a716623a8a0d154546265797d1 238 Gene3D G3DSA:3.40.50.2300 2 139 1.0E-33 T 29-03-2018 CWR56_RS13305 4659b00d5683582c60bb913f93253e78 216 Gene3D G3DSA:1.10.10.60 2 36 2.7E-7 T 29-03-2018 CWR56_RS13305 4659b00d5683582c60bb913f93253e78 216 Gene3D G3DSA:1.10.260.40 37 181 3.4E-6 T 29-03-2018 CWR56_RS13305 4659b00d5683582c60bb913f93253e78 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 3.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS13305 4659b00d5683582c60bb913f93253e78 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS13305 4659b00d5683582c60bb913f93253e78 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS13305 4659b00d5683582c60bb913f93253e78 216 SUPERFAMILY SSF46689 7 68 1.98E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 Gene3D G3DSA:3.20.20.80 1 477 1.6E-154 T 29-03-2018 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 Pfam PF00232 Glycosyl hydrolase family 1 3 474 5.6E-133 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 1.0E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 1.0E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 1.0E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 1.0E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 307 321 1.0E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15465 c29578ed94fc0fbcfc237317d5b2fd31 477 SUPERFAMILY SSF51445 3 474 6.96E-162 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 Gene3D G3DSA:3.40.50.2300 1 125 1.4E-32 T 29-03-2018 CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 SUPERFAMILY SSF46894 126 227 3.97E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 Pfam PF00072 Response regulator receiver domain 3 112 8.6E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 1.8E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 SUPERFAMILY SSF52172 2 130 3.42E-38 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 Gene3D G3DSA:1.10.10.10 126 229 9.2E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 SMART SM00862 150 226 4.3E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS03035 834b3c5dcf7f357bbef73a0b20b4fe90 229 SMART SM00448 1 111 2.1E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 Gene3D G3DSA:1.10.287.130 64 138 3.5E-10 T 29-03-2018 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 SMART SM00387 189 299 4.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 Pfam PF00512 His Kinase A (phospho-acceptor) domain 82 144 1.8E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 195 296 3.7E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 PRINTS PR00344 Bacterial sensor protein C-terminal signature 226 240 2.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 277 2.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 296 2.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 PRINTS PR00344 Bacterial sensor protein C-terminal signature 244 254 2.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 Gene3D G3DSA:3.30.565.10 139 297 3.0E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 SUPERFAMILY SSF47384 69 144 3.14E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 SMART SM00388 78 144 3.4E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS09315 153378c59dcbd66b8e4ff57087244823 302 SUPERFAMILY SSF55874 134 295 2.23E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 Pfam PF00082 Subtilase family 684 862 1.9E-14 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 Pfam PF00082 Subtilase family 392 516 5.8E-17 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 Pfam PF00082 Subtilase family 1000 1104 1.1E-15 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 Pfam PF00082 Subtilase family 87 260 1.9E-12 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 169 5.1E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 PRINTS PR00723 Subtilisin serine protease family (S8) signature 87 106 5.1E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 PRINTS PR00723 Subtilisin serine protease family (S8) signature 458 474 5.1E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 Gene3D G3DSA:3.40.50.200 663 1132 5.2E-57 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 Gene3D G3DSA:3.40.50.200 60 543 8.6E-59 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 SUPERFAMILY SSF52743 678 859 6.55E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 SUPERFAMILY SSF52743 999 1129 6.55E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 459 469 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 SUPERFAMILY SSF52743 396 523 7.59E-49 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 SUPERFAMILY SSF52743 153 257 7.59E-49 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS10880 ecaa514f316c20fb007d7fb91a7af965 1132 SUPERFAMILY SSF52743 76 128 7.59E-49 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS18190 548426d5f1736ffc96b64d8fade2a135 246 Gene3D G3DSA:3.20.20.70 4 245 1.9E-120 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS18190 548426d5f1736ffc96b64d8fade2a135 246 SUPERFAMILY SSF51569 72 228 5.86E-7 T 29-03-2018 CWR56_RS18190 548426d5f1736ffc96b64d8fade2a135 246 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 8 243 9.8E-129 T 29-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CWR56_RS18190 548426d5f1736ffc96b64d8fade2a135 246 Pfam PF07071 KDGP aldolase 8 225 1.9E-116 T 29-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CWR56_RS06605 faf51f75b37bf98f56390b29608a676a 194 Pfam PF00882 Zinc dependent phospholipase C 5 157 3.6E-26 T 29-03-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 CWR56_RS11515 6a400f539709991a2ee633e010567c0f 526 SUPERFAMILY SSF47384 293 372 5.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS11515 6a400f539709991a2ee633e010567c0f 526 SMART SM00388 305 371 3.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS11515 6a400f539709991a2ee633e010567c0f 526 Pfam PF00512 His Kinase A (phospho-acceptor) domain 305 371 5.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS11515 6a400f539709991a2ee633e010567c0f 526 SUPERFAMILY SSF55874 360 508 2.15E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS11515 6a400f539709991a2ee633e010567c0f 526 Gene3D G3DSA:1.10.287.130 296 365 2.0E-14 T 29-03-2018 CWR56_RS11515 6a400f539709991a2ee633e010567c0f 526 Gene3D G3DSA:3.30.565.10 366 513 8.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 Pfam PF01751 Toprim domain 3 136 4.0E-18 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 Gene3D G3DSA:2.70.20.10 351 463 4.4E-25 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 Gene3D G3DSA:1.10.460.10 160 350 2.3E-30 T 29-03-2018 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 Gene3D G3DSA:1.10.460.10 464 596 4.6E-19 T 29-03-2018 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 SUPERFAMILY SSF56712 1 589 3.01E-153 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 Pfam PF01131 DNA topoisomerase 153 573 4.7E-114 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 Gene3D G3DSA:3.40.50.140 1 155 1.4E-40 T 29-03-2018 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 SMART SM00437 267 538 4.5E-58 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 SMART SM00436 127 219 3.9E-18 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 SMART SM00493 1 127 1.0E-17 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 189 207 6.6E-22 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 501 515 6.6E-22 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 6.6E-22 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 389 405 6.6E-22 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 6.6E-22 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR56_RS12135 1b118333e0bd0bd400c447f0472711e7 742 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 305 323 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 Pfam PF12802 MarR family 38 97 3.0E-11 T 29-03-2018 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 Gene3D G3DSA:1.10.10.10 1 188 2.4E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 SMART SM00347 29 133 3.3E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS07440 1b193c8fa44c12c3ac6611163b994c56 188 SUPERFAMILY SSF46785 11 149 1.08E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03200 74bf944be2723e1dab65a726803b4fe3 156 SUPERFAMILY SSF54593 1 118 4.05E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS03200 74bf944be2723e1dab65a726803b4fe3 156 Pfam PF12681 Glyoxalase-like domain 5 121 5.3E-49 T 29-03-2018 IPR025870 Glyoxalase-like domain CWR56_RS03200 74bf944be2723e1dab65a726803b4fe3 156 Gene3D G3DSA:3.10.180.10 6 132 4.5E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 SUPERFAMILY SSF47203 266 491 1.69E-75 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 Gene3D G3DSA:2.40.110.10 145 277 3.8E-21 T 29-03-2018 CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 Gene3D G3DSA:1.10.3140.10 3 144 5.9E-55 T 29-03-2018 CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 PIRSF PIRSF000331 1 497 7.4E-184 T 29-03-2018 IPR004925 HpaB/PvcC/4-BUDH CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 275 1.6E-110 T 29-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 283 489 7.8E-78 T 29-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 Gene3D G3DSA:1.20.140.10 284 489 1.4E-75 T 29-03-2018 CWR56_RS11635 b563f986d4c3677313aed03850c7ed58 498 SUPERFAMILY SSF56645 3 276 1.18E-96 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 SUPERFAMILY SSF55811 5 133 3.38E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 Pfam PF00293 NUDIX domain 9 127 2.2E-22 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 29 138 0.001 T 29-03-2018 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 PRINTS PR00502 NUDIX hydrolase family signature 41 56 2.0E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 PRINTS PR00502 NUDIX hydrolase family signature 27 41 2.0E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS16915 0fd5d26f2c3db7090d08c0260c731426 141 Gene3D G3DSA:3.90.79.10 1 141 4.1E-28 T 29-03-2018 CWR56_RS14230 f7239108132cb97a100ac8167b74542f 341 Pfam PF02547 Queuosine biosynthesis protein 3 340 3.0E-147 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR56_RS14230 f7239108132cb97a100ac8167b74542f 341 Gene3D G3DSA:3.40.1780.10 173 341 6.4E-70 T 29-03-2018 CWR56_RS14230 f7239108132cb97a100ac8167b74542f 341 Gene3D G3DSA:3.40.1780.10 1 133 5.4E-44 T 29-03-2018 CWR56_RS14230 f7239108132cb97a100ac8167b74542f 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 340 8.8E-143 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR56_RS14230 f7239108132cb97a100ac8167b74542f 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 46.74 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR56_RS14230 f7239108132cb97a100ac8167b74542f 341 SUPERFAMILY SSF111337 1 340 2.49E-142 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR56_RS04700 7f278cfbb7433f076a6633e20ecabd5e 418 Gene3D G3DSA:3.90.550.10 41 316 8.9E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS04700 7f278cfbb7433f076a6633e20ecabd5e 418 Pfam PF13641 Glycosyltransferase like family 2 52 281 2.3E-35 T 29-03-2018 CWR56_RS04700 7f278cfbb7433f076a6633e20ecabd5e 418 SUPERFAMILY SSF53448 48 318 4.18E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 Gene3D G3DSA:1.10.4100.10 186 375 1.3E-30 T 29-03-2018 CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 Gene3D G3DSA:3.30.1330.90 10 63 1.2E-15 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 Gene3D G3DSA:3.30.1330.90 64 118 3.5E-12 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 Pfam PF03315 Serine dehydratase beta chain 68 115 7.4E-9 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 Pfam PF03315 Serine dehydratase beta chain 5 58 2.8E-16 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 Pfam PF03313 Serine dehydratase alpha chain 147 391 3.8E-85 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 SUPERFAMILY SSF143548 16 116 4.18E-26 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR56_RS16190 b9ae68438d63f3ade7879528a6c2863d 397 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 70 392 1.7E-106 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWR56_RS03970 df6480f7b0353c06bf05adc06a9537fe 136 Gene3D G3DSA:3.40.50.620 3 136 3.5E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS03970 df6480f7b0353c06bf05adc06a9537fe 136 PRINTS PR01438 Universal stress protein signature 3 21 8.1E-12 T 29-03-2018 IPR006015 Universal stress protein A CWR56_RS03970 df6480f7b0353c06bf05adc06a9537fe 136 PRINTS PR01438 Universal stress protein signature 113 135 8.1E-12 T 29-03-2018 IPR006015 Universal stress protein A CWR56_RS03970 df6480f7b0353c06bf05adc06a9537fe 136 PRINTS PR01438 Universal stress protein signature 96 108 8.1E-12 T 29-03-2018 IPR006015 Universal stress protein A CWR56_RS03970 df6480f7b0353c06bf05adc06a9537fe 136 Pfam PF00582 Universal stress protein family 4 135 1.7E-18 T 29-03-2018 IPR006016 UspA GO:0006950 CWR56_RS03970 df6480f7b0353c06bf05adc06a9537fe 136 SUPERFAMILY SSF52402 1 135 1.17E-23 T 29-03-2018 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 Pfam PF00625 Guanylate kinase 8 185 1.5E-50 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 7 184 9.1E-74 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 SUPERFAMILY SSF52540 4 190 5.0E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 Gene3D G3DSA:3.40.50.300 84 187 2.0E-29 T 29-03-2018 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 187 36.798 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 Gene3D G3DSA:3.40.50.300 1 50 3.5E-9 T 29-03-2018 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 Gene3D G3DSA:3.30.63.10 51 83 9.6E-27 T 29-03-2018 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CWR56_RS13090 6bb39db0c169312dc5acd880218aa114 205 SMART SM00072 5 187 1.7E-60 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CWR56_RS15190 95bfac9d8f303418efc48cfca948e277 365 Gene3D G3DSA:3.20.20.70 3 239 2.3E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS15190 95bfac9d8f303418efc48cfca948e277 365 SUPERFAMILY SSF50891 246 361 9.1E-36 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS15190 95bfac9d8f303418efc48cfca948e277 365 SUPERFAMILY SSF51445 1 243 1.26E-86 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS15190 95bfac9d8f303418efc48cfca948e277 365 Gene3D G3DSA:2.40.100.10 245 360 4.2E-42 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS15190 95bfac9d8f303418efc48cfca948e277 365 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 361 2.0E-139 T 29-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CWR56_RS00415 4a3d6b0fed19e20c5000ba97794186b7 179 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 8 155 7.2E-46 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CWR56_RS00415 4a3d6b0fed19e20c5000ba97794186b7 179 SUPERFAMILY SSF102114 22 100 2.62E-13 T 29-03-2018 CWR56_RS00415 4a3d6b0fed19e20c5000ba97794186b7 179 PIRSF PIRSF000368 1 170 6.4E-51 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CWR56_RS00415 4a3d6b0fed19e20c5000ba97794186b7 179 Pfam PF04055 Radical SAM superfamily 24 109 1.8E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS00415 4a3d6b0fed19e20c5000ba97794186b7 179 Gene3D G3DSA:3.80.30.10 48 171 2.7E-17 T 29-03-2018 CWR56_RS00415 4a3d6b0fed19e20c5000ba97794186b7 179 Pfam PF13353 4Fe-4S single cluster domain 15 153 1.6E-37 T 29-03-2018 CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 19 142 2.0E-45 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 Gene3D G3DSA:2.40.280.10 19 137 5.1E-51 T 29-03-2018 IPR023620 Small protein B CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 Hamap MF_00023 SsrA-binding protein [smpB]. 1 163 69.626 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 TIGRFAM TIGR00086 smpB: SsrA-binding protein 19 159 3.8E-58 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 Pfam PF01668 SmpB protein 20 160 2.1E-62 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 ProSitePatterns PS01317 SsrA-binding protein. 37 49 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site CWR56_RS15845 7ef9338659ce053ae5425f53f6965a78 163 SUPERFAMILY SSF74982 16 142 3.14E-52 T 29-03-2018 IPR023620 Small protein B CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 SUPERFAMILY SSF53187 484 669 8.48E-48 T 29-03-2018 CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 Pfam PF04122 Putative cell wall binding repeat 2 269 358 1.0E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 Pfam PF04122 Putative cell wall binding repeat 2 374 454 6.5E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 Pfam PF04122 Putative cell wall binding repeat 2 169 254 5.9E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 SMART SM00646 544 666 2.3E-20 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 Gene3D G3DSA:3.40.630.40 481 670 3.6E-51 T 29-03-2018 CWR56_RS04750 311afb8aae9d04ad8ffc9e0e67141075 670 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 486 666 5.1E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 Gene3D G3DSA:3.40.710.10 383 974 8.1E-84 T 29-03-2018 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 Pfam PF03717 Penicillin-binding Protein dimerisation domain 53 368 2.9E-55 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 SUPERFAMILY SSF56519 47 116 9.03E-42 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 SUPERFAMILY SSF56519 254 382 9.03E-42 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 Gene3D G3DSA:3.90.1310.10 22 382 3.8E-48 T 29-03-2018 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 Pfam PF00905 Penicillin binding protein transpeptidase domain 428 815 5.7E-51 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR56_RS05210 60688288068d971410b16bdd050f282e 992 SUPERFAMILY SSF56601 479 597 1.56E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS05210 60688288068d971410b16bdd050f282e 992 SUPERFAMILY SSF56601 334 451 1.56E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS05210 60688288068d971410b16bdd050f282e 992 SUPERFAMILY SSF56601 704 805 1.56E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS01580 afd19c4f75c1a8be432b074ea23f97de 147 Gene3D G3DSA:1.25.40.10 8 103 3.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01580 afd19c4f75c1a8be432b074ea23f97de 147 SUPERFAMILY SSF48452 12 92 1.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS07530 2f2377375be4fdc15e64d2f9132c941b 316 Gene3D G3DSA:1.10.3470.10 14 307 9.5E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS07530 2f2377375be4fdc15e64d2f9132c941b 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 303 3.5E-47 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWR56_RS12680 32c9768fc8bdc92dbb72d001dc5837a8 516 Gene3D G3DSA:3.30.1360.60 439 513 2.7E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS12680 32c9768fc8bdc92dbb72d001dc5837a8 516 Pfam PF02378 Phosphotransferase system, EIIC 14 352 3.8E-50 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS12680 32c9768fc8bdc92dbb72d001dc5837a8 516 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 453 470 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS12680 32c9768fc8bdc92dbb72d001dc5837a8 516 SUPERFAMILY SSF55604 442 513 1.44E-18 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS12680 32c9768fc8bdc92dbb72d001dc5837a8 516 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 411 499 8.9E-17 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS12680 32c9768fc8bdc92dbb72d001dc5837a8 516 Pfam PF00367 phosphotransferase system, EIIB 443 475 3.2E-16 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS08060 495687cf8aacf9aafd72367bb741e749 224 Gene3D G3DSA:1.10.10.60 2 42 3.1E-5 T 29-03-2018 CWR56_RS08060 495687cf8aacf9aafd72367bb741e749 224 Gene3D G3DSA:1.10.1220.10 159 223 1.7E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 Gene3D G3DSA:3.40.50.2030 235 405 1.8E-47 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 Pfam PF03063 Prismane/CO dehydrogenase family 46 607 2.4E-141 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 Gene3D G3DSA:1.20.1270.30 62 231 3.3E-52 T 29-03-2018 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 Gene3D G3DSA:3.40.50.2030 410 626 8.3E-67 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 PIRSF PIRSF005023 1 627 1.2E-227 T 29-03-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 9 626 5.0E-246 T 29-03-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CWR56_RS00860 3b29eea4a0e501b98a4d9791f176e60f 633 SUPERFAMILY SSF56821 19 626 1.44E-150 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 Pfam PF00581 Rhodanese-like domain 8 125 1.6E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 Gene3D G3DSA:3.40.250.10 1 135 2.4E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 16 322 3.1E-95 T 29-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 SUPERFAMILY SSF52540 139 256 1.82E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 SUPERFAMILY SSF52540 287 347 1.82E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 Gene3D G3DSA:3.40.50.300 136 350 1.3E-7 T 29-03-2018 CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 SUPERFAMILY SSF52821 89 132 1.26E-23 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 SUPERFAMILY SSF52821 13 62 1.26E-23 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06160 eaa3a03434aa6075996aeb4cda7ae52f 352 SMART SM00450 1 130 3.9E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 SMART SM00994 9 48 1.8E-23 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Pfam PF07724 AAA domain (Cdc48 subfamily) 108 305 1.7E-48 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 1.0E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 1 407 2.6E-201 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 52.864 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Gene3D G3DSA:3.40.50.300 19 62 0.077 T 29-03-2018 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 SUPERFAMILY SSF57716 10 45 8.84E-12 T 29-03-2018 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 SMART SM01086 312 408 1.0E-32 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Pfam PF06689 ClpX C4-type zinc finger 11 47 2.5E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Gene3D G3DSA:1.10.8.60 312 404 4.7E-34 T 29-03-2018 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 SUPERFAMILY SSF52540 60 395 5.21E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 Gene3D G3DSA:3.40.50.300 63 310 7.2E-71 T 29-03-2018 CWR56_RS16615 e290dbc8cf1bf2c73f3ea77d20a614f6 416 SMART SM00382 108 261 3.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 SUPERFAMILY SSF53850 91 297 1.99E-22 T 29-03-2018 CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 Gene3D G3DSA:3.40.190.10 181 267 6.1E-7 T 29-03-2018 CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 Gene3D G3DSA:1.10.10.10 1 85 3.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 Gene3D G3DSA:3.40.190.10 90 180 3.7E-14 T 29-03-2018 CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 6.9E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 SUPERFAMILY SSF46785 1 111 2.99E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13530 f2b1b37fc1671346102b75a4fa33f102 300 Pfam PF03466 LysR substrate binding domain 91 291 1.4E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS03550 39dda7a180a4d7f99da58e1ea9f32031 271 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 183 1.7E-14 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR56_RS03550 39dda7a180a4d7f99da58e1ea9f32031 271 SUPERFAMILY SSF55681 1 270 2.65E-61 T 29-03-2018 CWR56_RS03550 39dda7a180a4d7f99da58e1ea9f32031 271 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 1 271 61.78 T 29-03-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CWR56_RS03550 39dda7a180a4d7f99da58e1ea9f32031 271 Gene3D G3DSA:3.30.930.10 1 271 5.4E-53 T 29-03-2018 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.965 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 Pfam PF00281 Ribosomal protein L5 25 81 1.6E-27 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 Gene3D G3DSA:3.30.1440.10 2 180 1.5E-77 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 SUPERFAMILY SSF55282 4 179 2.17E-76 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 2.7E-39 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00145 495fe822ff3e72a40c1883ef45d702e9 180 PIRSF PIRSF002161 1 180 1.6E-67 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS13120 138ff35c4da190bd2b82b866a5772e91 403 Pfam PF00860 Permease family 2 359 2.9E-80 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS13120 138ff35c4da190bd2b82b866a5772e91 403 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 2 392 1.3E-89 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR56_RS13120 138ff35c4da190bd2b82b866a5772e91 403 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 307 327 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 Gene3D G3DSA:3.30.1360.60 2 76 2.9E-28 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 538 550 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 475 597 1.4E-49 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 SUPERFAMILY SSF55604 6 79 1.07E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 597 1.3E-208 T 29-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 Gene3D G3DSA:2.70.70.10 462 599 2.2E-52 T 29-03-2018 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 SUPERFAMILY SSF51261 468 597 6.8E-51 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 476 596 2.3E-45 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 Pfam PF00367 phosphotransferase system, EIIB 8 41 5.0E-16 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS03990 08430f76cbc6f8274064c81bb6e4f684 599 Pfam PF02378 Phosphotransferase system, EIIC 109 392 7.4E-29 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS02170 1760ad131a6d8a658bfaf318348acc0d 225 Pfam PF03358 NADPH-dependent FMN reductase 1 132 5.9E-21 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS02170 1760ad131a6d8a658bfaf318348acc0d 225 SUPERFAMILY SSF52218 3 151 3.88E-27 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS02170 1760ad131a6d8a658bfaf318348acc0d 225 Gene3D G3DSA:3.40.50.360 3 223 3.4E-28 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS09430 819a4c00c993f688b54d4753a7cc1fb6 337 Gene3D G3DSA:3.40.190.10 143 337 7.4E-29 T 29-03-2018 CWR56_RS09430 819a4c00c993f688b54d4753a7cc1fb6 337 Gene3D G3DSA:3.40.190.10 39 142 3.3E-18 T 29-03-2018 CWR56_RS09430 819a4c00c993f688b54d4753a7cc1fb6 337 SUPERFAMILY SSF53850 43 326 2.12E-49 T 29-03-2018 CWR56_RS09430 819a4c00c993f688b54d4753a7cc1fb6 337 Pfam PF09084 NMT1/THI5 like 51 265 1.9E-74 T 29-03-2018 IPR015168 SsuA/THI5-like CWR56_RS00680 1b0795e853ed93b854e9a49267dda680 183 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 125 179 4.0E-26 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CWR56_RS00680 1b0795e853ed93b854e9a49267dda680 183 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 4.7E-25 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS00680 1b0795e853ed93b854e9a49267dda680 183 Gene3D G3DSA:3.30.160.100 1 97 9.0E-28 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS00680 1b0795e853ed93b854e9a49267dda680 183 SUPERFAMILY SSF69754 2 103 1.2E-30 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS00680 1b0795e853ed93b854e9a49267dda680 183 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 183 22.798 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CWR56_RS00680 1b0795e853ed93b854e9a49267dda680 183 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 3.5E-27 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR56_RS11365 8c86b6e715b8eb421535ca999463be7e 77 Gene3D G3DSA:1.10.260.40 1 77 4.9E-17 T 29-03-2018 CWR56_RS11365 8c86b6e715b8eb421535ca999463be7e 77 SUPERFAMILY SSF47413 2 62 6.44E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS11365 8c86b6e715b8eb421535ca999463be7e 77 Pfam PF01381 Helix-turn-helix 5 59 2.0E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11365 8c86b6e715b8eb421535ca999463be7e 77 SMART SM00530 4 59 6.1E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 SUPERFAMILY SSF88659 78 153 1.4E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 225 8.0E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 Gene3D G3DSA:1.10.10.10 81 125 3.0E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 Gene3D G3DSA:1.10.601.10 1 76 2.3E-24 T 29-03-2018 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 196 222 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 PIRSF PIRSF000770 1 231 8.7E-37 T 29-03-2018 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 Pfam PF04545 Sigma-70, region 4 175 224 1.2E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 6 226 1.6E-67 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 Gene3D G3DSA:1.10.10.10 148 232 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 Pfam PF04539 Sigma-70 region 3 85 161 6.6E-11 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 Pfam PF04542 Sigma-70 region 2 6 76 1.3E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 PRINTS PR00046 Major sigma-70 factor signature 179 191 6.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 PRINTS PR00046 Major sigma-70 factor signature 196 211 6.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 PRINTS PR00046 Major sigma-70 factor signature 211 222 6.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 PRINTS PR00046 Major sigma-70 factor signature 32 45 6.1E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 SUPERFAMILY SSF88659 141 228 9.91E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01360 2ff7525ef2ced83de63c96bfc042e22b 233 SUPERFAMILY SSF88946 3 76 1.44E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Gene3D G3DSA:1.10.8.60 351 492 2.0E-41 T 29-03-2018 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Pfam PF02151 UvrB/uvrC motif 425 458 7.7E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 SUPERFAMILY SSF52540 166 470 1.41E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Gene3D G3DSA:3.40.50.300 164 349 1.3E-26 T 29-03-2018 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 576 594 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 SMART SM01086 723 812 2.7E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 SMART SM00382 205 350 1.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 SMART SM00382 542 686 1.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 326 2.5E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Gene3D G3DSA:1.10.1780.10 1 143 2.3E-30 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 301 313 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Gene3D G3DSA:1.10.8.60 723 815 1.4E-23 T 29-03-2018 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 143 1.6E-10 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 62 2.9E-13 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Gene3D G3DSA:3.40.50.300 497 722 7.3E-54 T 29-03-2018 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 1.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 1.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 1.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 1.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 723 802 1.5E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 SUPERFAMILY SSF81923 4 136 5.89E-26 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 SUPERFAMILY SSF52540 491 812 1.12E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18855 5ed2742f157c9bc4d7caec38ba4f14a4 815 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 717 9.2E-58 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 SMART SM00862 144 221 1.1E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 Pfam PF00072 Response regulator receiver domain 4 113 5.9E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 SUPERFAMILY SSF52172 1 125 4.13E-37 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 Gene3D G3DSA:1.10.10.10 117 226 9.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 SMART SM00448 2 112 1.8E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 Gene3D G3DSA:3.40.50.2300 1 116 2.4E-33 T 29-03-2018 CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 221 4.5E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS17915 59f982df95931220b4c27e552c42d9a2 228 SUPERFAMILY SSF46894 124 221 8.79E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS06755 3370ca98159d0a3a2229094462ae772b 197 Pfam PF02954 Bacterial regulatory protein, Fis family 150 193 2.0E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS06755 3370ca98159d0a3a2229094462ae772b 197 Gene3D G3DSA:1.10.10.60 147 195 3.2E-13 T 29-03-2018 CWR56_RS06755 3370ca98159d0a3a2229094462ae772b 197 SUPERFAMILY SSF46689 149 196 5.98E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS06025 7c351f272ce28494cb613f0c5c5eff46 146 Gene3D G3DSA:1.10.10.10 21 116 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06025 7c351f272ce28494cb613f0c5c5eff46 146 Pfam PF01047 MarR family 35 92 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06025 7c351f272ce28494cb613f0c5c5eff46 146 SMART SM00347 28 128 7.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06025 7c351f272ce28494cb613f0c5c5eff46 146 SUPERFAMILY SSF46785 6 143 5.73E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14745 fe08c96a58b3a6e56eaa616e43a90ec3 220 SUPERFAMILY SSF56037 57 215 4.18E-23 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS14745 fe08c96a58b3a6e56eaa616e43a90ec3 220 Gene3D G3DSA:3.50.40.10 44 194 1.7E-17 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS14745 fe08c96a58b3a6e56eaa616e43a90ec3 220 Pfam PF03483 B3/4 domain 65 191 2.0E-14 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS14745 fe08c96a58b3a6e56eaa616e43a90ec3 220 SMART SM00873 63 210 5.3E-11 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS01065 d0dbd9fe438ebab7bb2df3cee9477be9 132 Pfam PF01797 Transposase IS200 like 9 126 1.0E-40 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS01065 d0dbd9fe438ebab7bb2df3cee9477be9 132 Gene3D G3DSA:3.30.70.1290 1 125 7.0E-25 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS01065 d0dbd9fe438ebab7bb2df3cee9477be9 132 SMART SM01321 9 126 7.6E-42 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS01065 d0dbd9fe438ebab7bb2df3cee9477be9 132 SUPERFAMILY SSF143422 1 127 2.22E-46 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS07770 d0dbd9fe438ebab7bb2df3cee9477be9 132 Pfam PF01797 Transposase IS200 like 9 126 1.0E-40 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS07770 d0dbd9fe438ebab7bb2df3cee9477be9 132 Gene3D G3DSA:3.30.70.1290 1 125 7.0E-25 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS07770 d0dbd9fe438ebab7bb2df3cee9477be9 132 SMART SM01321 9 126 7.6E-42 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS07770 d0dbd9fe438ebab7bb2df3cee9477be9 132 SUPERFAMILY SSF143422 1 127 2.22E-46 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 SMART SM01097 1 131 7.5E-81 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 347 1.4E-127 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 Gene3D G3DSA:3.50.30.20 1 140 1.1E-56 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 130 3.5E-51 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 Gene3D G3DSA:3.40.50.880 141 347 7.8E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 Pfam PF00117 Glutamine amidotransferase class-I 172 344 7.5E-39 T 29-03-2018 IPR017926 Glutamine amidotransferase CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 1.5E-30 T 29-03-2018 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 1.5E-30 T 29-03-2018 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 1.5E-30 T 29-03-2018 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 1.5E-30 T 29-03-2018 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 1.5E-30 T 29-03-2018 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 347 40.873 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 SUPERFAMILY SSF52021 1 146 4.71E-54 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17935 398ee4afb81e079412dbf0c2299f3808 347 SUPERFAMILY SSF52317 149 346 5.92E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 SUPERFAMILY SSF161098 14 199 4.84E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 Gene3D G3DSA:3.40.190.10 234 390 6.5E-26 T 29-03-2018 CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 244 507 3.7E-61 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 Gene3D G3DSA:3.40.190.10 391 509 4.6E-21 T 29-03-2018 CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 Gene3D G3DSA:1.10.3720.10 5 212 1.6E-30 T 29-03-2018 CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 SUPERFAMILY SSF53850 243 510 1.74E-65 T 29-03-2018 CWR56_RS16155 e9d51794ad5a0b26240fe9fda06e27a1 511 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 211 2.3E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 Gene3D G3DSA:1.10.10.10 1 71 1.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 Pfam PF07729 FCD domain 96 221 4.9E-16 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 63 5.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 SUPERFAMILY SSF46785 3 73 1.58E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 6.9E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 6.9E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 SUPERFAMILY SSF48008 93 226 2.88E-13 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 SMART SM00345 10 69 2.7E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 Gene3D G3DSA:1.20.120.530 88 229 2.9E-15 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR56_RS03980 4df4792214bd9b30299d23e67a5fbb4d 230 SMART SM00895 95 222 4.7E-7 T 29-03-2018 IPR011711 GntR, C-terminal CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 ProSitePatterns PS00548 Ribosomal protein S3 signature. 164 198 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 Pfam PF00189 Ribosomal protein S3, C-terminal domain 121 203 1.3E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 Gene3D G3DSA:3.30.1140.32 109 209 2.1E-37 T 29-03-2018 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 207 37.327 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 Gene3D G3DSA:3.30.300.20 17 108 2.5E-30 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 Pfam PF07650 KH domain 40 109 7.8E-16 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 210 4.8E-90 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 SUPERFAMILY SSF54814 2 107 8.63E-36 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 SMART SM00322 61 126 1.1E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CWR56_RS00115 684ae1e8a49bcf2b3f85e9d328e6df01 271 SUPERFAMILY SSF54821 110 207 3.92E-38 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS13860 b829a90287721143078352ef7625bf49 480 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 13 458 1.2E-121 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CWR56_RS13860 b829a90287721143078352ef7625bf49 480 Pfam PF03553 Na+/H+ antiporter family 162 456 9.6E-53 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 Pfam PF01235 Sodium:alanine symporter family 63 459 1.4E-160 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 101 116 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 PRINTS PR00175 Sodium/alanine symporter signature 191 209 1.8E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 PRINTS PR00175 Sodium/alanine symporter signature 219 238 1.8E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 PRINTS PR00175 Sodium/alanine symporter signature 355 377 1.8E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 PRINTS PR00175 Sodium/alanine symporter signature 415 435 1.8E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 PRINTS PR00175 Sodium/alanine symporter signature 310 328 1.8E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 PRINTS PR00175 Sodium/alanine symporter signature 101 123 1.8E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS08110 54002404993d5c871f6a2607d11e3e61 483 TIGRFAM TIGR00835 agcS: amino acid carrier protein 23 446 6.3E-153 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS04060 f28eaa9e050d293bbc028d452dc99fc6 271 Pfam PF00753 Metallo-beta-lactamase superfamily 24 89 7.4E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04060 f28eaa9e050d293bbc028d452dc99fc6 271 SUPERFAMILY SSF56281 14 108 1.06E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04060 f28eaa9e050d293bbc028d452dc99fc6 271 SUPERFAMILY SSF56281 143 247 1.06E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04060 f28eaa9e050d293bbc028d452dc99fc6 271 Gene3D G3DSA:3.60.15.10 2 262 2.2E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 SUPERFAMILY SSF90123 2 315 6.41E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 Gene3D G3DSA:1.20.1560.10 1 317 4.5E-65 T 29-03-2018 CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 Pfam PF00005 ABC transporter 349 496 1.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 Gene3D G3DSA:3.40.50.300 318 574 2.4E-74 T 29-03-2018 CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 SUPERFAMILY SSF52540 324 568 1.03E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 Pfam PF00664 ABC transporter transmembrane region 16 281 3.4E-33 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS04635 0a66d8cfaffcc8e2df95249952f29679 575 SMART SM00382 358 543 1.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Pfam PF08279 HTH domain 9 58 1.2E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Pfam PF00874 PRD domain 314 398 3.9E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Pfam PF05043 Mga helix-turn-helix domain 96 170 1.9E-9 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Gene3D G3DSA:3.40.50.2300 408 514 2.2E-15 T 29-03-2018 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 SUPERFAMILY SSF55804 518 659 4.71E-25 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 521 659 1.2E-21 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Gene3D G3DSA:1.10.1790.10 168 287 0.0021 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Gene3D G3DSA:1.10.1790.10 289 403 4.3E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 SUPERFAMILY SSF52794 410 495 5.75E-9 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 SUPERFAMILY SSF63520 299 403 7.19E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Gene3D G3DSA:1.10.10.10 1 70 1.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Gene3D G3DSA:1.10.10.10 92 158 1.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 Gene3D G3DSA:3.40.930.10 517 661 2.0E-26 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS03700 868217df3cd38b1a163fed72aa9f0b15 661 SUPERFAMILY SSF63520 186 285 5.23E-5 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 Gene3D G3DSA:3.90.1170.30 343 429 9.1E-27 T 29-03-2018 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 Pfam PF00591 Glycosyl transferase family, a/b domain 83 310 6.6E-40 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 8 423 4.8E-168 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 Gene3D G3DSA:3.40.1030.10 73 342 4.7E-90 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 SMART SM00941 350 424 1.6E-28 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 SUPERFAMILY SSF47648 6 74 2.09E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 350 423 2.0E-20 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 SUPERFAMILY SSF52418 74 334 1.57E-89 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 PIRSF PIRSF000478 5 440 1.2E-155 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 SUPERFAMILY SSF54680 337 438 7.98E-27 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 115 130 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 Pfam PF02885 Glycosyl transferase family, helical bundle domain 10 71 1.2E-19 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR56_RS05600 4ab8e9bf40aeea1be367a46e0a05909d 446 Gene3D G3DSA:1.20.970.10 6 71 1.3E-22 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Gene3D G3DSA:3.50.50.60 231 352 3.8E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 124 572 2.7E-150 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Gene3D G3DSA:3.50.50.60 353 454 4.4E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Gene3D G3DSA:3.30.390.30 455 574 3.8E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 124 436 1.6E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 SUPERFAMILY SSF55424 451 573 8.25E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 158 168 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Gene3D G3DSA:1.10.287.990 156 224 4.0E-18 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 456 562 4.1E-29 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 401 423 8.0E-37 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 375 391 8.0E-37 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 145 8.0E-37 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 270 8.0E-37 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 309 8.0E-37 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Pfam PF00364 Biotin-requiring enzyme 4 69 7.5E-14 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 Gene3D G3DSA:3.90.1170.30 1 51 2.1E-12 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PIRSF PIRSF000350 73 559 4.4E-84 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 SUPERFAMILY SSF51230 1 91 1.18E-20 T 29-03-2018 IPR011053 Single hybrid motif CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 SUPERFAMILY SSF51905 118 445 3.76E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 515 530 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 316 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 423 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 147 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 264 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 537 557 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 390 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 172 2.8E-60 T 29-03-2018 CWR56_RS18920 165198e17a2a9320538ce00d1ecf720b 576 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 451 472 2.8E-60 T 29-03-2018 CWR56_RS07605 b4b08f560f108b820c71b90bdd455ada 210 Pfam PF02581 Thiamine monophosphate synthase 13 193 2.6E-62 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07605 b4b08f560f108b820c71b90bdd455ada 210 SUPERFAMILY SSF51391 9 206 1.11E-60 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07605 b4b08f560f108b820c71b90bdd455ada 210 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 205 7.5E-66 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07605 b4b08f560f108b820c71b90bdd455ada 210 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 208 25.761 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07605 b4b08f560f108b820c71b90bdd455ada 210 Gene3D G3DSA:3.20.20.70 2 209 7.6E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10055 1b454c5b540cdc5f72a1ef56c9cbde3a 240 Gene3D G3DSA:3.30.1330.20 132 239 3.5E-10 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWR56_RS10055 1b454c5b540cdc5f72a1ef56c9cbde3a 240 SUPERFAMILY SSF55307 134 238 2.52E-6 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CWR56_RS10055 1b454c5b540cdc5f72a1ef56c9cbde3a 240 Pfam PF12327 FtsZ family, C-terminal domain 187 236 2.8E-5 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CWR56_RS07035 54ec836cc55fadcb50bce295283dff01 202 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 4 202 2.5E-52 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR56_RS07035 54ec836cc55fadcb50bce295283dff01 202 SUPERFAMILY SSF50486 2 201 8.63E-56 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CWR56_RS07035 54ec836cc55fadcb50bce295283dff01 202 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 3 202 26.787 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR56_RS07035 54ec836cc55fadcb50bce295283dff01 202 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 1 201 1.6E-51 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR56_RS07035 54ec836cc55fadcb50bce295283dff01 202 Gene3D G3DSA:3.10.300.10 1 202 8.6E-61 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR56_RS03330 f69b08a0575512737df94b6583895e5a 193 SUPERFAMILY SSF46689 7 71 1.54E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS03330 f69b08a0575512737df94b6583895e5a 193 Gene3D G3DSA:1.10.10.60 6 42 4.7E-11 T 29-03-2018 CWR56_RS03330 f69b08a0575512737df94b6583895e5a 193 Gene3D G3DSA:1.10.260.40 43 154 4.2E-6 T 29-03-2018 CWR56_RS03330 f69b08a0575512737df94b6583895e5a 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 2.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS09920 15ca51e6e368e60c32be9d3f9423d3b1 339 Gene3D G3DSA:3.40.980.10 134 305 2.6E-41 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS09920 15ca51e6e368e60c32be9d3f9423d3b1 339 SUPERFAMILY SSF53218 169 303 2.49E-33 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS09920 15ca51e6e368e60c32be9d3f9423d3b1 339 Pfam PF00994 Probable molybdopterin binding domain 173 289 1.1E-20 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS09920 15ca51e6e368e60c32be9d3f9423d3b1 339 SMART SM00852 173 305 5.5E-22 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 Pfam PF01595 Domain of unknown function DUF21 9 202 1.0E-44 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 Gene3D G3DSA:3.10.580.10 197 342 4.6E-32 T 29-03-2018 CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 SMART SM01091 351 429 5.5E-20 T 29-03-2018 IPR005170 Transporter-associated domain CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 Gene3D G3DSA:3.30.465.10 343 429 4.0E-19 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 SUPERFAMILY SSF56176 346 426 2.15E-17 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 SMART SM00116 226 275 0.93 T 29-03-2018 IPR000644 CBS domain CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 SMART SM00116 288 336 0.37 T 29-03-2018 IPR000644 CBS domain CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 Pfam PF03471 Transporter associated domain 352 426 1.0E-14 T 29-03-2018 IPR005170 Transporter-associated domain CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 SUPERFAMILY SSF54631 212 353 2.78E-32 T 29-03-2018 CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 Pfam PF00571 CBS domain 219 270 4.4E-6 T 29-03-2018 IPR000644 CBS domain CWR56_RS14525 346f31db301ca471150b43b8d9df4367 429 Pfam PF00571 CBS domain 286 336 4.5E-8 T 29-03-2018 IPR000644 CBS domain CWR56_RS05710 eabbf2617d3f7b7f8b3e2e0322dbdfb1 129 SUPERFAMILY SSF46785 5 124 4.26E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05710 eabbf2617d3f7b7f8b3e2e0322dbdfb1 129 PIRSF PIRSF019455 1 129 6.3E-38 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS05710 eabbf2617d3f7b7f8b3e2e0322dbdfb1 129 Gene3D G3DSA:1.10.4040.10 72 121 5.8E-10 T 29-03-2018 CWR56_RS05710 eabbf2617d3f7b7f8b3e2e0322dbdfb1 129 Gene3D G3DSA:1.10.10.10 8 71 9.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05710 eabbf2617d3f7b7f8b3e2e0322dbdfb1 129 Pfam PF03965 Penicillinase repressor 8 119 1.2E-22 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS17635 2980d0a25b88eede2fbfcfbc2080e578 191 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 1 184 6.4E-51 T 29-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CWR56_RS17635 2980d0a25b88eede2fbfcfbc2080e578 191 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 2 186 2.1E-41 T 29-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CWR56_RS17635 2980d0a25b88eede2fbfcfbc2080e578 191 SUPERFAMILY SSF159709 5 187 6.54E-34 T 29-03-2018 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 Gene3D G3DSA:1.10.10.10 123 234 4.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 Pfam PF00072 Response regulator receiver domain 4 112 8.8E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 SUPERFAMILY SSF46894 128 227 1.28E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 SMART SM00448 2 112 1.3E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 Gene3D G3DSA:3.40.50.2300 1 122 5.9E-28 T 29-03-2018 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 3.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 SMART SM00862 150 227 2.8E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS12820 a9593d0e877b64d28d6d7173abf4d9a1 235 SUPERFAMILY SSF52172 2 130 2.99E-33 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 Pfam PF07739 TipAS antibiotic-recognition domain 135 249 8.2E-36 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 SUPERFAMILY SSF46955 3 110 8.79E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 Gene3D G3DSA:1.10.490.50 164 253 1.4E-28 T 29-03-2018 CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 SMART SM00422 3 72 1.0E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 Gene3D G3DSA:1.10.1660.10 1 144 1.0E-34 T 29-03-2018 CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 SUPERFAMILY SSF89082 164 251 1.15E-26 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.5E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.5E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.5E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS12965 7a74f7dd9a8358379a1db868f5bc2649 253 Pfam PF13411 MerR HTH family regulatory protein 3 71 6.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS10605 a97db0075fb3cab0545b102b09feb7f3 179 SUPERFAMILY SSF53323 3 178 4.45E-34 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CWR56_RS10605 a97db0075fb3cab0545b102b09feb7f3 179 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 175 2.0E-31 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS10605 a97db0075fb3cab0545b102b09feb7f3 179 Gene3D G3DSA:3.40.920.10 2 179 6.7E-40 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS02730 22ddbce131165a9e14d50bca4b4f73ba 91 SUPERFAMILY SSF54403 4 87 1.19E-10 T 29-03-2018 CWR56_RS02730 22ddbce131165a9e14d50bca4b4f73ba 91 Gene3D G3DSA:3.10.450.10 3 91 5.4E-5 T 29-03-2018 CWR56_RS07565 b679c3d2c68c0944c8dd599f466fc867 302 Gene3D G3DSA:3.40.50.1100 21 135 6.4E-34 T 29-03-2018 CWR56_RS07565 b679c3d2c68c0944c8dd599f466fc867 302 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 302 4.7E-122 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CWR56_RS07565 b679c3d2c68c0944c8dd599f466fc867 302 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 302 4.2E-120 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CWR56_RS07565 b679c3d2c68c0944c8dd599f466fc867 302 Gene3D G3DSA:3.40.50.1100 136 302 7.7E-60 T 29-03-2018 CWR56_RS07565 b679c3d2c68c0944c8dd599f466fc867 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 290 1.7E-72 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS07565 b679c3d2c68c0944c8dd599f466fc867 302 SUPERFAMILY SSF53686 2 299 5.24E-99 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 SUPERFAMILY SSF90123 29 358 4.84E-78 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 Gene3D G3DSA:1.20.1560.10 16 360 9.6E-82 T 29-03-2018 CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 SMART SM00382 400 586 2.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 SUPERFAMILY SSF52540 366 611 3.7E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 Pfam PF00005 ABC transporter 392 540 4.6E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 ProSitePatterns PS00211 ABC transporters family signature. 512 526 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 Pfam PF00664 ABC transporter transmembrane region 46 326 3.9E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS04640 3bb0cdbe1a4463c85a69e6b67b57dc7b 620 Gene3D G3DSA:3.40.50.300 361 616 1.3E-75 T 29-03-2018 CWR56_RS18425 8b7a3f1d042079464e94e6dbb3bc2e7c 83 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 15 83 25.109 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR56_RS18425 8b7a3f1d042079464e94e6dbb3bc2e7c 83 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 30 83 2.0E-20 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR56_RS18425 8b7a3f1d042079464e94e6dbb3bc2e7c 83 SMART SM01234 15 82 1.1E-45 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR56_RS18425 8b7a3f1d042079464e94e6dbb3bc2e7c 83 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 20 81 1.2E-30 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR56_RS18425 8b7a3f1d042079464e94e6dbb3bc2e7c 83 Pfam PF01809 Haemolytic domain 17 81 2.5E-31 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 Gene3D G3DSA:3.90.930.12 87 179 9.0E-43 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.41 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 SUPERFAMILY SSF56053 1 83 3.01E-25 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 PIRSF PIRSF002162 1 178 3.6E-52 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 Gene3D G3DSA:3.90.930.12 5 86 9.5E-29 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 Pfam PF00347 Ribosomal protein L6 11 83 1.7E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 Pfam PF00347 Ribosomal protein L6 92 165 7.0E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 6.6E-77 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 SUPERFAMILY SSF56053 84 178 2.88E-38 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 PRINTS PR00059 Ribosomal protein L6 signature 72 97 7.0E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 PRINTS PR00059 Ribosomal protein L6 signature 100 116 7.0E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR56_RS00160 b7bf7fdae73b5ef66bcd302d88562625 180 PRINTS PR00059 Ribosomal protein L6 signature 142 163 7.0E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR56_RS08720 750066d366225c5aa89af36ed9f35840 65 SUPERFAMILY SSF103473 5 65 2.09E-8 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS08720 750066d366225c5aa89af36ed9f35840 65 Gene3D G3DSA:1.20.1250.20 2 65 4.7E-8 T 29-03-2018 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 PIRSF PIRSF000497 1 395 1.9E-176 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 394 58.66 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 SUPERFAMILY SSF55973 121 243 1.81E-51 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 SUPERFAMILY SSF55973 3 110 7.46E-48 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 270 278 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 392 4.0E-184 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 244 383 1.5E-69 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Gene3D G3DSA:3.30.300.10 11 143 6.6E-45 T 29-03-2018 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 100 8.3E-45 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Gene3D G3DSA:3.30.300.10 259 395 2.3E-48 T 29-03-2018 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 SUPERFAMILY SSF55973 244 392 1.26E-69 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Gene3D G3DSA:3.30.300.10 144 244 8.0E-47 T 29-03-2018 CWR56_RS00620 33776b2348dde591d181accb6bb886c8 397 Pfam PF02772 S-adenosylmethionine synthetase, central domain 126 242 7.9E-49 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 Gene3D G3DSA:1.10.1660.10 1 59 1.9E-18 T 29-03-2018 CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 SUPERFAMILY SSF46955 2 107 1.36E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 Pfam PF13411 MerR HTH family regulatory protein 2 70 7.4E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 SMART SM00871 119 270 5.9E-24 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 SMART SM00422 2 72 7.2E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 Gene3D G3DSA:3.20.80.10 123 271 4.1E-25 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 SUPERFAMILY SSF55136 120 272 6.98E-18 T 29-03-2018 CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 Gene3D G3DSA:1.10.1660.10 60 122 2.5E-4 T 29-03-2018 CWR56_RS03325 f90c091290d3e471eebbe91b96eb32d8 272 Pfam PF06445 GyrI-like small molecule binding domain 120 270 2.7E-13 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS03960 2f089065e585904b4c80dabd19822446 162 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CWR56_RS03960 2f089065e585904b4c80dabd19822446 162 Gene3D G3DSA:3.40.50.360 1 162 6.7E-22 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS03960 2f089065e585904b4c80dabd19822446 162 SUPERFAMILY SSF52218 2 160 5.63E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS03960 2f089065e585904b4c80dabd19822446 162 Pfam PF00258 Flavodoxin 5 92 5.7E-10 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CWR56_RS05480 0b8a47c044c0c55b698f882ddb7a7c3a 169 Pfam PF01029 NusB family 11 165 9.0E-53 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS05480 0b8a47c044c0c55b698f882ddb7a7c3a 169 SUPERFAMILY SSF48013 8 42 2.75E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS05480 0b8a47c044c0c55b698f882ddb7a7c3a 169 SUPERFAMILY SSF48013 73 166 2.75E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS05480 0b8a47c044c0c55b698f882ddb7a7c3a 169 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 4 168 20.938 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CWR56_RS05480 0b8a47c044c0c55b698f882ddb7a7c3a 169 Gene3D G3DSA:1.10.940.10 7 169 1.6E-42 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR56_RS05480 0b8a47c044c0c55b698f882ddb7a7c3a 169 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 9 166 3.9E-41 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 SUPERFAMILY SSF55186 554 709 2.09E-52 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 856 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 Pfam PF01411 tRNA synthetases class II (A) 8 557 9.1E-200 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 SMART SM00863 655 698 5.0E-23 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 Gene3D G3DSA:3.30.980.10 555 714 2.2E-46 T 29-03-2018 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 Pfam PF02272 DHHA1 domain 736 874 2.9E-25 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 SUPERFAMILY SSF55681 4 243 3.23E-95 T 29-03-2018 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 Gene3D G3DSA:3.30.930.10 3 240 1.7E-103 T 29-03-2018 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 4.6E-19 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 SUPERFAMILY SSF50447 456 554 4.17E-17 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 175.979 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 SUPERFAMILY SSF101353 244 461 1.18E-65 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 197 208 1.5E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 1.5E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.5E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 224 237 1.5E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR56_RS05940 fec87d7dd3e3e56a14d4c799f7a9a537 879 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 1.5E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR56_RS11460 1e81bf1f4b5c9b7af9c09329e4d7e372 62 SUPERFAMILY SSF46689 1 48 3.94E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS01220 4fd2faed426e0bfbe381d1e7f18af8d5 704 Pfam PF13712 Glycosyltransferase like family 7 217 1.1E-85 T 29-03-2018 CWR56_RS01220 4fd2faed426e0bfbe381d1e7f18af8d5 704 Gene3D G3DSA:3.90.550.10 23 185 3.5E-4 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01220 4fd2faed426e0bfbe381d1e7f18af8d5 704 SUPERFAMILY SSF53448 15 167 1.56E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01220 4fd2faed426e0bfbe381d1e7f18af8d5 704 SUPERFAMILY SSF53756 318 572 2.2E-9 T 29-03-2018 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 Gene3D G3DSA:1.10.1740.10 27 109 7.4E-20 T 29-03-2018 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 Pfam PF04542 Sigma-70 region 2 43 111 2.1E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 212 1.0E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 SUPERFAMILY SSF88946 11 111 2.62E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 PIRSF PIRSF002939 7 220 3.1E-101 T 29-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 SUPERFAMILY SSF88659 129 217 2.88E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 Gene3D G3DSA:1.10.10.10 127 220 1.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 23 216 1.2E-104 T 29-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS19015 dc611800228054c49fba168e36a58fc6 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 215 6.7E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15175 6522b6f56f1899938bc19460703217ff 283 Gene3D G3DSA:1.10.10.10 1 77 5.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15175 6522b6f56f1899938bc19460703217ff 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 74 1.1E-21 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS15175 6522b6f56f1899938bc19460703217ff 283 Pfam PF01380 SIS domain 126 253 8.9E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS15175 6522b6f56f1899938bc19460703217ff 283 Gene3D G3DSA:3.40.50.10490 85 281 1.7E-34 T 29-03-2018 CWR56_RS15175 6522b6f56f1899938bc19460703217ff 283 SUPERFAMILY SSF53697 95 277 7.59E-42 T 29-03-2018 CWR56_RS15175 6522b6f56f1899938bc19460703217ff 283 SUPERFAMILY SSF46689 1 76 2.15E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 8.8E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 Pfam PF00005 ABC transporter 35 185 5.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 302 2.2E-14 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 SMART SM00382 43 235 3.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 Gene3D G3DSA:3.40.50.300 4 323 3.8E-81 T 29-03-2018 CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS13505 6e7c8505105c864d1ea8ff2292608a90 323 SUPERFAMILY SSF52540 7 257 6.12E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14785 9c2d57ddb36cbec25e8d494e8e5b552d 181 PIRSF PIRSF016661 1 181 1.6E-40 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CWR56_RS14785 9c2d57ddb36cbec25e8d494e8e5b552d 181 Pfam PF02632 BioY family 33 173 7.4E-34 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CWR56_RS12155 a98f5d46aff0a2f1640ed59b7fb16f4f 436 SUPERFAMILY SSF56954 321 421 1.31E-9 T 29-03-2018 CWR56_RS12155 a98f5d46aff0a2f1640ed59b7fb16f4f 436 Pfam PF02321 Outer membrane efflux protein 322 427 2.2E-10 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CWR56_RS12155 a98f5d46aff0a2f1640ed59b7fb16f4f 436 Gene3D G3DSA:1.20.1600.10 38 428 7.3E-29 T 29-03-2018 CWR56_RS12155 a98f5d46aff0a2f1640ed59b7fb16f4f 436 SUPERFAMILY SSF56954 55 212 9.94E-10 T 29-03-2018 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 Pfam PF00012 Hsp70 protein 78 578 7.5E-217 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 SUPERFAMILY SSF53067 1 159 8.2E-58 T 29-03-2018 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 Gene3D G3DSA:2.60.34.10 362 503 3.3E-65 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 611 36.913 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 SUPERFAMILY SSF100920 356 512 1.44E-61 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 578 2.9E-284 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 SUPERFAMILY SSF100934 506 581 2.47E-9 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 SUPERFAMILY SSF53067 163 354 1.48E-66 T 29-03-2018 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 309 323 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 Gene3D G3DSA:3.30.420.40 173 338 1.1E-48 T 29-03-2018 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 Gene3D G3DSA:1.20.1270.10 504 592 5.0E-21 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 Gene3D G3DSA:3.30.420.40 1 172 2.9E-68 T 29-03-2018 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 306 322 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 174 184 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 441 457 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 337 357 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 PRINTS PR00301 70kDa heat shock protein signature 360 379 2.1E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR56_RS12440 650767392fc21d6eed279cb67b0fdc87 615 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 SUPERFAMILY SSF52540 280 487 1.5E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 Gene3D G3DSA:3.40.50.300 3 263 9.4E-39 T 29-03-2018 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 SUPERFAMILY SSF52540 3 180 7.72E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 Pfam PF00005 ABC transporter 92 126 1.0E-6 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 Pfam PF00005 ABC transporter 23 80 2.1E-7 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 Pfam PF00005 ABC transporter 304 430 4.0E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 ProSitePatterns PS00211 ABC transporters family signature. 98 112 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 SMART SM00382 28 178 8.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 SMART SM00382 313 475 2.5E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13115 3e57d24c7c9e16f7b5bef3501eb75274 550 Gene3D G3DSA:3.40.50.300 264 508 2.7E-44 T 29-03-2018 CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 Pfam PF04122 Putative cell wall binding repeat 2 33 116 2.6E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 Pfam PF04122 Putative cell wall binding repeat 2 221 291 1.8E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 Pfam PF04122 Putative cell wall binding repeat 2 128 212 1.3E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 Gene3D G3DSA:3.40.33.10 391 529 5.2E-10 T 29-03-2018 IPR014044 CAP domain CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 SUPERFAMILY SSF55797 401 529 1.31E-10 T 29-03-2018 IPR014044 CAP domain CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 Gene3D G3DSA:2.60.40.10 307 388 2.5E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS14175 babf2a64492cfac63dd67a2b3a205f7c 532 Pfam PF00188 Cysteine-rich secretory protein family 405 523 2.8E-9 T 29-03-2018 IPR014044 CAP domain CWR56_RS12060 bb1c5981700c7f6e5809865c95bef2d5 124 Gene3D G3DSA:1.10.10.10 6 70 5.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12060 bb1c5981700c7f6e5809865c95bef2d5 124 SUPERFAMILY SSF46785 3 123 3.29E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12060 bb1c5981700c7f6e5809865c95bef2d5 124 PIRSF PIRSF019455 1 124 4.0E-34 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS12060 bb1c5981700c7f6e5809865c95bef2d5 124 Pfam PF03965 Penicillinase repressor 7 118 3.0E-24 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS12060 bb1c5981700c7f6e5809865c95bef2d5 124 Gene3D G3DSA:1.10.4040.10 71 120 1.9E-9 T 29-03-2018 CWR56_RS12325 422574bc7e65266e54f471a521cb5411 153 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 11 152 22.808 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWR56_RS12325 422574bc7e65266e54f471a521cb5411 153 Gene3D G3DSA:3.40.390.30 1 152 6.7E-49 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CWR56_RS12325 422574bc7e65266e54f471a521cb5411 153 SUPERFAMILY SSF55486 11 152 2.2E-42 T 29-03-2018 CWR56_RS12325 422574bc7e65266e54f471a521cb5411 153 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 148 8.9E-40 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWR56_RS12325 422574bc7e65266e54f471a521cb5411 153 Pfam PF02130 Uncharacterized protein family UPF0054 15 148 1.0E-44 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWR56_RS02590 301c4754bbac4806c39ef6e40c0f4de3 134 SUPERFAMILY SSF103084 2 121 3.79E-20 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CWR56_RS02590 301c4754bbac4806c39ef6e40c0f4de3 134 Gene3D G3DSA:3.30.1330.70 1 125 1.4E-23 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CWR56_RS02590 301c4754bbac4806c39ef6e40c0f4de3 134 Pfam PF05866 Endodeoxyribonuclease RusA 7 119 5.0E-21 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CWR56_RS14650 f6d68077a6ced3d848efd52305e4a5e1 437 PIRSF PIRSF006351 1 437 8.3E-123 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS14650 f6d68077a6ced3d848efd52305e4a5e1 437 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 431 2.0E-111 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR56_RS14650 f6d68077a6ced3d848efd52305e4a5e1 437 Pfam PF02378 Phosphotransferase system, EIIC 29 360 3.0E-45 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS08525 7add70eeee6396212c1d941b52b2d9f7 125 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 15 121 8.4E-22 T 29-03-2018 IPR010181 CGCAxxGCC motif CWR56_RS08525 7add70eeee6396212c1d941b52b2d9f7 125 SUPERFAMILY SSF48695 9 102 1.97E-8 T 29-03-2018 IPR011031 Multihaem cytochrome CWR56_RS08525 7add70eeee6396212c1d941b52b2d9f7 125 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 15 118 2.6E-16 T 29-03-2018 IPR010181 CGCAxxGCC motif CWR56_RS17360 7dcaab138ab560ae5706659bde1a8702 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 208 3.2E-67 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CWR56_RS17360 7dcaab138ab560ae5706659bde1a8702 346 PIRSF PIRSF004930 1 346 4.4E-127 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CWR56_RS17360 7dcaab138ab560ae5706659bde1a8702 346 Pfam PF01300 Telomere recombination 24 199 1.2E-55 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CWR56_RS17360 7dcaab138ab560ae5706659bde1a8702 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 340 3.0E-26 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CWR56_RS17360 7dcaab138ab560ae5706659bde1a8702 346 SUPERFAMILY SSF55821 7 212 1.77E-63 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR56_RS17360 7dcaab138ab560ae5706659bde1a8702 346 Gene3D G3DSA:3.90.870.10 2 215 7.1E-73 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR56_RS14005 10d1398e2ff5027dc837561d09eeab8e 301 SMART SM00646 180 292 1.7E-37 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS14005 10d1398e2ff5027dc837561d09eeab8e 301 Gene3D G3DSA:3.40.630.40 114 301 3.9E-62 T 29-03-2018 CWR56_RS14005 10d1398e2ff5027dc837561d09eeab8e 301 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 119 292 2.2E-54 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS14005 10d1398e2ff5027dc837561d09eeab8e 301 SUPERFAMILY SSF53187 117 296 2.13E-53 T 29-03-2018 CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 PIRSF PIRSF037238 6 386 2.2E-96 T 29-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 Gene3D G3DSA:3.40.630.10 2 286 4.9E-49 T 29-03-2018 CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 SUPERFAMILY SSF55031 189 301 2.09E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 Pfam PF07687 Peptidase dimerisation domain 186 288 1.6E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 SUPERFAMILY SSF53187 4 198 1.72E-48 T 29-03-2018 CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 SUPERFAMILY SSF53187 310 385 1.72E-48 T 29-03-2018 CWR56_RS14325 ed8ae437afd46dcbcfc04fa1f8fef748 390 Pfam PF01546 Peptidase family M20/M25/M40 84 383 2.7E-23 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 Pfam PF02743 Cache domain 49 274 7.8E-15 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 Gene3D G3DSA:3.30.450.20 163 281 4.6E-13 T 29-03-2018 CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 SUPERFAMILY SSF55073 359 515 1.18E-32 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 Gene3D G3DSA:3.30.70.270 347 516 4.1E-37 T 29-03-2018 CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 SMART SM00267 343 516 5.4E-28 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 Gene3D G3DSA:3.30.450.20 42 162 2.3E-4 T 29-03-2018 CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 353 513 6.0E-32 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13970 d63ff08c0219d3a47a1ea7ea4d76fe5f 516 Pfam PF00990 Diguanylate cyclase, GGDEF domain 356 511 5.2E-31 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 Pfam PF13187 4Fe-4S dicluster domain 8 53 2.6E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 SUPERFAMILY SSF55469 172 267 5.76E-38 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 SUPERFAMILY SSF55469 78 136 5.76E-38 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 Gene3D G3DSA:3.40.109.10 69 270 1.0E-33 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 Gene3D G3DSA:3.40.50.1780 44 68 0.032 T 29-03-2018 CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 Pfam PF00881 Nitroreductase family 82 254 1.2E-28 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 SUPERFAMILY SSF54862 1 76 4.38E-19 T 29-03-2018 CWR56_RS03395 fce68fa1dd9fd7e226edf8f37e141511 273 Gene3D G3DSA:3.30.70.20 1 43 1.8E-13 T 29-03-2018 CWR56_RS09440 823ef6fef98648953b877444694da97c 96 Pfam PF01910 Thiamine-binding protein 4 95 7.2E-27 T 29-03-2018 IPR002767 Thiamine-binding protein CWR56_RS09440 823ef6fef98648953b877444694da97c 96 Gene3D G3DSA:3.30.70.930 1 96 1.7E-25 T 29-03-2018 IPR029756 MTH1187/YkoF-like CWR56_RS09440 823ef6fef98648953b877444694da97c 96 SUPERFAMILY SSF89957 1 95 5.89E-25 T 29-03-2018 IPR029756 MTH1187/YkoF-like CWR56_RS09440 823ef6fef98648953b877444694da97c 96 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 92 2.0E-17 T 29-03-2018 IPR002767 Thiamine-binding protein CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Pfam PF13474 SnoaL-like domain 19 130 1.6E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SUPERFAMILY SSF55073 424 576 6.83E-36 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 285 5.6E-10 T 29-03-2018 IPR000014 PAS domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SMART SM00267 408 576 3.6E-41 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Gene3D G3DSA:3.30.450.20 145 280 1.5E-17 T 29-03-2018 CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Gene3D G3DSA:3.30.450.20 281 421 6.8E-16 T 29-03-2018 CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Pfam PF08447 PAS fold 185 264 8.8E-13 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SUPERFAMILY SSF54427 22 111 4.84E-7 T 29-03-2018 IPR032710 NTF2-like domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SUPERFAMILY SSF55785 181 279 8.55E-17 T 29-03-2018 IPR000014 PAS domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SMART SM00086 237 278 4.3E-4 T 29-03-2018 IPR001610 PAC motif CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SMART SM00086 364 408 0.027 T 29-03-2018 IPR001610 PAC motif CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 417 574 1.9E-37 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Pfam PF13426 PAS domain 359 407 0.32 T 29-03-2018 IPR000014 PAS domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 SUPERFAMILY SSF55785 275 406 3.14E-9 T 29-03-2018 IPR000014 PAS domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Pfam PF00990 Diguanylate cyclase, GGDEF domain 419 571 4.8E-36 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Gene3D G3DSA:3.30.70.270 422 577 1.1E-41 T 29-03-2018 CWR56_RS06665 8f36237862d24062083949a1d11ac7ae 577 Gene3D G3DSA:3.10.450.50 18 143 7.8E-10 T 29-03-2018 CWR56_RS07455 f560bd03dd7bf4ad629b0180df8886b4 173 Pfam PF13673 Acetyltransferase (GNAT) domain 28 126 3.4E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS07455 f560bd03dd7bf4ad629b0180df8886b4 173 Gene3D G3DSA:3.40.630.30 3 162 1.6E-11 T 29-03-2018 CWR56_RS07455 f560bd03dd7bf4ad629b0180df8886b4 173 SUPERFAMILY SSF55729 14 134 1.89E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS09740 7be3553d6a6445b59c9bf762b69aec3e 179 Gene3D G3DSA:3.40.630.30 1 163 4.9E-14 T 29-03-2018 CWR56_RS09740 7be3553d6a6445b59c9bf762b69aec3e 179 SUPERFAMILY SSF55729 1 142 4.15E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS09740 7be3553d6a6445b59c9bf762b69aec3e 179 Pfam PF13508 Acetyltransferase (GNAT) domain 51 133 1.0E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS07190 ed09fc5b1efd44537a8cc0ad5706c8e4 146 Pfam PF13673 Acetyltransferase (GNAT) domain 40 146 8.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS07190 ed09fc5b1efd44537a8cc0ad5706c8e4 146 SUPERFAMILY SSF55729 3 146 8.61E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS07190 ed09fc5b1efd44537a8cc0ad5706c8e4 146 Gene3D G3DSA:3.40.630.30 1 146 1.2E-27 T 29-03-2018 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 54 129 9.8E-16 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 SUPERFAMILY SSF51445 155 571 6.94E-90 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 Gene3D G3DSA:3.20.20.80 123 569 2.4E-80 T 29-03-2018 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 SMART SM00642 185 555 7.9E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 Gene3D G3DSA:2.60.40.10 47 122 9.2E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 SUPERFAMILY SSF81296 47 144 8.75E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 PIRSF PIRSF000463 1 665 3.6E-179 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 Pfam PF00128 Alpha amylase, catalytic domain 197 269 2.8E-13 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 578 662 1.8E-8 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 Gene3D G3DSA:2.60.40.1180 573 666 6.1E-11 T 29-03-2018 CWR56_RS12770 5c240da3d7dc16813b411796cb267d1d 667 SUPERFAMILY SSF51011 576 662 3.31E-9 T 29-03-2018 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 Pfam PF01336 OB-fold nucleic acid binding domain 66 142 8.8E-14 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 17 498 4.8E-196 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 23 500 43.477 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 195 205 1.6E-37 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 381 397 1.6E-37 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 211 227 1.6E-37 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 258 275 1.6E-37 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 253 1.6E-37 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 Gene3D G3DSA:3.30.930.10 152 496 6.9E-97 T 29-03-2018 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 SUPERFAMILY SSF55681 158 497 1.65E-114 T 29-03-2018 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 Gene3D G3DSA:2.40.50.140 17 151 1.1E-35 T 29-03-2018 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 PIRSF PIRSF039101 1 509 8.6E-194 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 SUPERFAMILY SSF50249 15 151 4.5E-37 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS17735 7079d0b328afe2b7c9ba1fc08154b62d 509 Pfam PF00152 tRNA synthetases class II (D, K and N) 158 496 7.0E-78 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS01335 8b7b858d97f9a9592cf122f38b9e4dd1 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 4.2E-29 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CWR56_RS01335 8b7b858d97f9a9592cf122f38b9e4dd1 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 85 6.0E-29 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CWR56_RS01335 8b7b858d97f9a9592cf122f38b9e4dd1 89 PIRSF PIRSF004669 1 89 1.4E-30 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CWR56_RS01335 8b7b858d97f9a9592cf122f38b9e4dd1 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.8E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CWR56_RS01335 8b7b858d97f9a9592cf122f38b9e4dd1 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.8E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CWR56_RS01335 8b7b858d97f9a9592cf122f38b9e4dd1 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.8E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CWR56_RS07945 a83b2864c8043380fe42f4512bd9914f 614 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 18 338 9.6E-71 T 29-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain CWR56_RS07945 a83b2864c8043380fe42f4512bd9914f 614 SUPERFAMILY SSF51695 360 594 2.09E-62 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR56_RS07945 a83b2864c8043380fe42f4512bd9914f 614 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 364 591 3.4E-33 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWR56_RS07945 a83b2864c8043380fe42f4512bd9914f 614 Gene3D G3DSA:3.20.20.190 358 604 1.2E-61 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR56_RS17890 45f5eaa68cafa7ea06ce18a545074bc4 221 SUPERFAMILY SSF55120 2 215 1.17E-51 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS17890 45f5eaa68cafa7ea06ce18a545074bc4 221 Gene3D G3DSA:3.30.2350.10 1 220 6.3E-56 T 29-03-2018 CWR56_RS17890 45f5eaa68cafa7ea06ce18a545074bc4 221 Pfam PF00849 RNA pseudouridylate synthase 10 166 3.7E-33 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS14795 40dd79df51f25686e8e7f95d047d3f76 142 SUPERFAMILY SSF55729 1 139 4.39E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS14795 40dd79df51f25686e8e7f95d047d3f76 142 Pfam PF13673 Acetyltransferase (GNAT) domain 48 141 6.7E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS14795 40dd79df51f25686e8e7f95d047d3f76 142 Gene3D G3DSA:3.40.630.30 1 142 6.2E-22 T 29-03-2018 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Gene3D G3DSA:3.90.320.10 1043 1275 9.4E-32 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Gene3D G3DSA:3.40.50.300 475 646 4.8E-21 T 29-03-2018 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1094 1258 3.8E-7 T 29-03-2018 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Gene3D G3DSA:1.10.486.10 647 814 8.3E-33 T 29-03-2018 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 3 1275 19.102 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 5 1272 0.0 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 461 1.3E-75 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Gene3D G3DSA:3.40.50.300 2 474 6.2E-51 T 29-03-2018 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 SUPERFAMILY SSF52540 344 501 2.38E-117 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 SUPERFAMILY SSF52540 5 175 2.38E-117 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 SUPERFAMILY SSF52540 901 930 2.38E-117 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 SUPERFAMILY SSF52540 573 859 2.38E-117 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 SUPERFAMILY SSF52980 1050 1267 5.9E-34 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWR56_RS04775 e33e6e4296b71ff75f6d21d722a8ec28 1275 Pfam PF13361 UvrD-like helicase C-terminal domain 472 924 7.1E-32 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 Gene3D G3DSA:3.40.50.40 210 330 6.5E-34 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 SUPERFAMILY SSF53774 4 328 7.2E-99 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 PIRSF PIRSF001220 1 330 5.9E-88 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 PIRSF PIRSF500176 3 330 1.4E-84 T 29-03-2018 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 SMART SM00870 6 322 1.6E-133 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 PRINTS PR00139 Asparaginase/glutaminase family signature 7 18 5.6E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 PRINTS PR00139 Asparaginase/glutaminase family signature 257 275 5.6E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 PRINTS PR00139 Asparaginase/glutaminase family signature 84 102 5.6E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 9 17 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 Gene3D G3DSA:3.40.50.1170 2 209 2.7E-47 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CWR56_RS12710 72bcfb69ad4b67ca993ee52666568b3f 331 Pfam PF00710 Asparaginase, N-terminal 6 192 7.1E-51 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 Pfam PF00563 EAL domain 758 985 1.0E-43 T 29-03-2018 IPR001633 EAL domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 Gene3D G3DSA:3.30.70.270 566 743 2.4E-39 T 29-03-2018 CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 SMART SM00052 752 992 6.1E-20 T 29-03-2018 IPR001633 EAL domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 Gene3D G3DSA:3.30.450.20 255 389 3.0E-12 T 29-03-2018 CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 Pfam PF00990 Diguanylate cyclase, GGDEF domain 582 734 1.4E-34 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 SUPERFAMILY SSF55073 585 738 1.02E-36 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 582 739 1.7E-33 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 Gene3D G3DSA:3.20.20.450 754 1003 3.4E-52 T 29-03-2018 IPR001633 EAL domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 SMART SM00267 569 742 2.7E-32 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 SUPERFAMILY SSF141868 758 989 3.27E-52 T 29-03-2018 IPR001633 EAL domain CWR56_RS03630 d6df55402608f5c5bc424dc873807deb 1011 Gene3D G3DSA:3.30.450.20 112 254 0.0043 T 29-03-2018 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SUPERFAMILY SSF158472 33 77 9.81E-6 T 29-03-2018 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SUPERFAMILY SSF55874 259 422 4.19E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SMART SM00091 86 151 2.5E-4 T 29-03-2018 IPR000014 PAS domain CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 Pfam PF00989 PAS fold 87 193 5.8E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 423 4.7E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SUPERFAMILY SSF47384 191 268 1.73E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SMART SM00388 202 269 3.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 Gene3D G3DSA:3.30.565.10 273 426 1.5E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SMART SM00304 27 79 3.7E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SUPERFAMILY SSF55785 76 147 1.07E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 4.6E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 4.6E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 4.6E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 4.6E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 Gene3D G3DSA:1.10.287.130 208 264 1.5E-18 T 29-03-2018 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 SMART SM00387 314 426 1.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 264 3.0E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 Gene3D G3DSA:3.30.450.20 85 207 9.0E-15 T 29-03-2018 CWR56_RS13345 897e452fa441788760f1a7de4ee60389 429 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 87 201 1.6E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 SUPERFAMILY SSF50465 301 326 2.3E-5 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 SUPERFAMILY SSF52540 6 221 4.94E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 PRINTS PR00315 GTP-binding elongation factor signature 59 67 1.4E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.4E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.4E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.4E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.4E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 SUPERFAMILY SSF50447 207 302 8.84E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.2E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 326 7.5E-183 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 Gene3D G3DSA:3.40.50.300 1 207 1.4E-43 T 29-03-2018 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.0E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 Gene3D G3DSA:2.40.30.10 208 326 2.5E-35 T 29-03-2018 CWR56_RS19020 df0404ddb1df0f371159a7e28709db0f 326 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 9.5E-16 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 Gene3D G3DSA:1.10.287.890 199 280 2.2E-27 T 29-03-2018 CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 SUPERFAMILY SSF52540 132 211 4.2E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 SUPERFAMILY SSF52540 6 57 4.2E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 SUPERFAMILY SSF52540 252 307 4.2E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 Pfam PF01715 IPP transferase 39 282 2.8E-79 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 SUPERFAMILY SSF52540 6 151 3.66E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 290 1.9E-93 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 Gene3D G3DSA:3.40.50.300 2 198 1.2E-62 T 29-03-2018 CWR56_RS09410 975a8a079a0968808bb51ef164572e10 311 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 300 29.251 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 Pfam PF14526 Integron-associated effector binding protein 123 271 2.5E-16 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 SUPERFAMILY SSF55136 119 272 3.14E-12 T 29-03-2018 CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 Pfam PF13411 MerR HTH family regulatory protein 2 70 5.0E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 SMART SM00422 2 72 9.2E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 SUPERFAMILY SSF46955 2 107 4.4E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 Gene3D G3DSA:3.20.80.10 130 273 1.1E-22 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 SMART SM00871 118 272 8.3E-17 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS02900 2b799d5ab452587595bf129954638f8e 274 Gene3D G3DSA:1.10.1660.10 1 129 1.1E-25 T 29-03-2018 CWR56_RS06505 1854f9b4be1f8f26a4eb0d184edad4db 114 Gene3D G3DSA:3.30.1330.40 2 114 7.2E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR56_RS06505 1854f9b4be1f8f26a4eb0d184edad4db 114 Pfam PF01042 Endoribonuclease L-PSP 7 112 7.9E-23 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CWR56_RS06505 1854f9b4be1f8f26a4eb0d184edad4db 114 SUPERFAMILY SSF55298 3 113 1.35E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR56_RS06505 1854f9b4be1f8f26a4eb0d184edad4db 114 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 89 107 - T 29-03-2018 IPR019897 RidA, conserved site CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 247 1.9E-109 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 SUPERFAMILY SSF51735 6 248 2.65E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 1.1E-4 T 29-03-2018 CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 Gene3D G3DSA:3.40.50.720 1 42 3.7E-10 T 29-03-2018 CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 Gene3D G3DSA:3.40.50.720 43 249 1.1E-71 T 29-03-2018 CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.1E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.1E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.1E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 6.8E-74 T 29-03-2018 CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS05385 f207cb36f33d7f781002e4b25f3ee04f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS10350 e6e3bad81dbf82494695b3e5e23f42e6 419 Pfam PF04294 VanW like protein 241 368 4.1E-44 T 29-03-2018 IPR007391 Vancomycin resistance VanW CWR56_RS10350 e6e3bad81dbf82494695b3e5e23f42e6 419 Pfam PF12229 Putative peptidoglycan binding domain 88 203 1.5E-15 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 SUPERFAMILY SSF53686 5 315 1.14E-98 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 307 3.4E-83 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 Gene3D G3DSA:3.40.50.1100 28 133 6.1E-33 T 29-03-2018 CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 SUPERFAMILY SSF55021 330 399 7.25E-8 T 29-03-2018 CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 23 402 9.4E-144 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 Gene3D G3DSA:3.30.70.260 329 403 5.1E-9 T 29-03-2018 CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 Gene3D G3DSA:3.40.50.1100 134 328 2.3E-48 T 29-03-2018 CWR56_RS12700 88c8958daf611945ce83f52603fbc8b6 405 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 Pfam PF00772 DnaB-like helicase N terminal domain 4 87 5.9E-14 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 SMART SM00382 183 364 3.2E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 SUPERFAMILY SSF48024 6 106 2.48E-10 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 Gene3D G3DSA:3.40.50.300 167 429 2.2E-36 T 29-03-2018 CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 SUPERFAMILY SSF52540 166 422 4.42E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 Pfam PF03796 DnaB-like helicase C terminal domain 166 429 7.4E-49 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWR56_RS02945 5950e51faab0515ca4810a5b35d86ba0 433 Gene3D G3DSA:1.10.860.10 3 138 1.7E-10 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CWR56_RS07550 92bf55fb8eb69633054cd3fa78613b48 564 Pfam PF03814 Potassium-transporting ATPase A subunit 12 560 5.1E-248 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR56_RS07550 92bf55fb8eb69633054cd3fa78613b48 564 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 3 562 32.975 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR56_RS07550 92bf55fb8eb69633054cd3fa78613b48 564 PIRSF PIRSF001294 3 564 8.5E-249 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR56_RS07550 92bf55fb8eb69633054cd3fa78613b48 564 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 7 561 6.3E-210 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 SUPERFAMILY SSF55681 1 280 1.99E-130 T 29-03-2018 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 57.917 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 288 8.3E-156 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 8.7E-150 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 Gene3D G3DSA:3.30.930.10 1 204 7.4E-86 T 29-03-2018 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 2.8E-64 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 2.8E-64 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 2.8E-64 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 2.8E-64 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 2.8E-64 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 2.8E-64 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWR56_RS12285 228785e66093d6cb6b4421277bcc4ecb 292 Gene3D G3DSA:1.20.58.180 206 282 2.5E-32 T 29-03-2018 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Gene3D G3DSA:2.30.38.10 544 629 1.8E-22 T 29-03-2018 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 SUPERFAMILY SSF52777 6 218 3.0E-21 T 29-03-2018 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Pfam PF00501 AMP-binding enzyme 250 635 4.3E-80 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 SUPERFAMILY SSF56801 208 729 7.2E-126 T 29-03-2018 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Pfam PF00668 Condensation domain 6 229 5.2E-20 T 29-03-2018 IPR001242 Condensation domain CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Gene3D G3DSA:3.40.50.980 395 543 1.4E-20 T 29-03-2018 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Gene3D G3DSA:3.30.300.30 630 729 4.3E-25 T 29-03-2018 CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Pfam PF13193 AMP-binding enzyme C-terminal domain 644 721 1.7E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 271 659 1.0E-106 T 29-03-2018 IPR010071 Amino acid adenylation domain CWR56_RS06560 86a23806bd2466309c69a1eb5db32921 729 Gene3D G3DSA:3.40.50.980 241 394 1.3E-37 T 29-03-2018 CWR56_RS16990 1dffc7b456842b5d8a5d8205d6ad0322 420 Gene3D G3DSA:3.40.720.10 2 411 4.9E-44 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR56_RS16990 1dffc7b456842b5d8a5d8205d6ad0322 420 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 281 5.4E-46 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CWR56_RS16990 1dffc7b456842b5d8a5d8205d6ad0322 420 SUPERFAMILY SSF53649 2 403 8.5E-64 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR56_RS09970 c7c78d36929da401e256dc5413d9afda 437 Gene3D G3DSA:2.30.40.10 1 69 6.0E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09970 c7c78d36929da401e256dc5413d9afda 437 Gene3D G3DSA:3.20.20.140 70 378 1.3E-40 T 29-03-2018 CWR56_RS09970 c7c78d36929da401e256dc5413d9afda 437 Pfam PF01979 Amidohydrolase family 55 407 5.5E-45 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS09970 c7c78d36929da401e256dc5413d9afda 437 SUPERFAMILY SSF51556 58 358 3.78E-64 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS09970 c7c78d36929da401e256dc5413d9afda 437 SUPERFAMILY SSF51338 2 58 3.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09970 c7c78d36929da401e256dc5413d9afda 437 SUPERFAMILY SSF51338 360 435 3.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 Gene3D G3DSA:3.30.420.40 149 294 5.9E-17 T 29-03-2018 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 336 63.232 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 311 1.3E-112 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 Gene3D G3DSA:3.30.420.40 4 148 1.6E-41 T 29-03-2018 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 1.1E-135 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 7.2E-46 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 7.2E-46 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 7.2E-46 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 7.2E-46 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 7.2E-46 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 7.2E-46 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 SUPERFAMILY SSF53067 104 316 6.15E-43 T 29-03-2018 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 Pfam PF00814 Glycoprotease family 26 311 1.9E-102 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00730 b44ba6a2a85b5f4837dee437fb8c7678 338 SUPERFAMILY SSF53067 6 126 3.3E-31 T 29-03-2018 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Gene3D G3DSA:1.10.10.10 3 73 1.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Pfam PF00874 PRD domain 861 938 3.0E-10 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Pfam PF00874 PRD domain 483 567 4.6E-8 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Pfam PF00158 Sigma-54 interaction domain 112 277 3.4E-44 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 SUPERFAMILY SSF53062 579 694 4.32E-21 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 SMART SM00382 134 284 3.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Gene3D G3DSA:1.10.1790.10 809 944 4.0E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 SUPERFAMILY SSF63520 467 569 7.19E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Gene3D G3DSA:3.40.50.510 564 717 7.6E-31 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Gene3D G3DSA:3.40.50.300 86 325 7.6E-25 T 29-03-2018 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 207 222 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Gene3D G3DSA:1.10.1790.10 438 563 2.1E-8 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 SUPERFAMILY SSF63520 835 942 3.53E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Pfam PF03610 PTS system fructose IIA component 580 692 6.6E-15 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 Gene3D G3DSA:3.40.50.2300 718 808 3.6E-7 T 29-03-2018 CWR56_RS02360 61702266fa48d4b399c13680e4515114 944 SUPERFAMILY SSF52540 113 345 9.08E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01120 1605661b8ab67e6868d28256592ea5e8 290 SUPERFAMILY SSF51735 1 285 1.63E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS01120 1605661b8ab67e6868d28256592ea5e8 290 Gene3D G3DSA:3.90.25.10 203 271 2.3E-25 T 29-03-2018 CWR56_RS01120 1605661b8ab67e6868d28256592ea5e8 290 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 284 6.8E-97 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CWR56_RS01120 1605661b8ab67e6868d28256592ea5e8 290 Pfam PF04321 RmlD substrate binding domain 1 285 5.3E-99 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CWR56_RS01120 1605661b8ab67e6868d28256592ea5e8 290 Gene3D G3DSA:3.40.50.720 1 202 2.0E-34 T 29-03-2018 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 Gene3D G3DSA:3.30.70.20 26 46 4.3E-13 T 29-03-2018 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 Gene3D G3DSA:1.10.1060.10 2 25 2.0E-4 T 29-03-2018 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 Pfam PF13237 4Fe-4S dicluster domain 9 56 4.2E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 Gene3D G3DSA:3.30.70.20 47 71 2.2E-5 T 29-03-2018 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 Pfam PF00881 Nitroreductase family 87 241 1.7E-25 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 SUPERFAMILY SSF54862 7 77 1.01E-20 T 29-03-2018 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 Gene3D G3DSA:3.40.109.10 72 243 7.0E-28 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 16 27 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS15605 3725a8a6f761203d064576172287df1d 260 SUPERFAMILY SSF55469 83 258 2.75E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS16585 1ba56a0f95a8f13daa8dea41d795684c 359 Gene3D G3DSA:3.40.50.300 15 49 0.24 T 29-03-2018 CWR56_RS16585 1ba56a0f95a8f13daa8dea41d795684c 359 Gene3D G3DSA:3.40.50.300 189 234 0.013 T 29-03-2018 CWR56_RS16585 1ba56a0f95a8f13daa8dea41d795684c 359 Gene3D G3DSA:3.40.50.300 50 188 0.05 T 29-03-2018 CWR56_RS16585 1ba56a0f95a8f13daa8dea41d795684c 359 SUPERFAMILY SSF52540 209 258 2.69E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16585 1ba56a0f95a8f13daa8dea41d795684c 359 SUPERFAMILY SSF52540 26 89 1.45E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16585 1ba56a0f95a8f13daa8dea41d795684c 359 Gene3D G3DSA:3.40.50.300 235 327 0.32 T 29-03-2018 CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 SUPERFAMILY SSF54862 86 107 2.01E-19 T 29-03-2018 CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 SUPERFAMILY SSF54862 155 281 2.01E-19 T 29-03-2018 CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Gene3D G3DSA:3.30.70.20 266 298 1.9E-6 T 29-03-2018 CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 263 274 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Pfam PF12801 4Fe-4S binding domain 77 113 3.3E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Pfam PF12801 4Fe-4S binding domain 59 70 63.0 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Pfam PF12801 4Fe-4S binding domain 133 168 2.7E-4 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Pfam PF12801 4Fe-4S binding domain 192 225 3.9E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Gene3D G3DSA:3.30.70.20 208 245 9.0E-10 T 29-03-2018 CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Pfam PF00037 4Fe-4S binding domain 262 279 1.2E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS07120 c6661870758333d71a95394b344c88d2 299 Gene3D G3DSA:3.30.70.20 246 265 2.4E-7 T 29-03-2018 CWR56_RS18260 2e0cb9bf9ab7a6467e8018d36598cc20 265 Pfam PF00753 Metallo-beta-lactamase superfamily 11 100 1.7E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS18260 2e0cb9bf9ab7a6467e8018d36598cc20 265 SUPERFAMILY SSF56281 3 223 1.27E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS18260 2e0cb9bf9ab7a6467e8018d36598cc20 265 Gene3D G3DSA:3.60.15.10 9 262 1.3E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS18260 2e0cb9bf9ab7a6467e8018d36598cc20 265 SMART SM00849 12 193 2.1E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS00550 32b878cd0ab5d2827fc8e63f9274c323 359 Gene3D G3DSA:3.40.50.970 1 274 1.1E-59 T 29-03-2018 CWR56_RS00550 32b878cd0ab5d2827fc8e63f9274c323 359 SUPERFAMILY SSF52922 240 351 4.71E-27 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS00550 32b878cd0ab5d2827fc8e63f9274c323 359 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 248 341 6.7E-24 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CWR56_RS00550 32b878cd0ab5d2827fc8e63f9274c323 359 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 228 3.1E-50 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CWR56_RS00550 32b878cd0ab5d2827fc8e63f9274c323 359 SUPERFAMILY SSF52518 1 238 1.83E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 SUPERFAMILY SSF52943 4 291 1.16E-78 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 PRINTS PR00126 ATP synthase gamma subunit signature 269 290 1.6E-35 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 1.6E-35 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 PRINTS PR00126 ATP synthase gamma subunit signature 162 179 1.6E-35 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 PRINTS PR00126 ATP synthase gamma subunit signature 238 257 1.6E-35 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 291 5.1E-90 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 Gene3D G3DSA:1.10.287.80 245 286 1.5E-12 T 29-03-2018 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 Hamap MF_00815 ATP synthase gamma chain [atpG]. 3 291 32.094 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 Pfam PF00231 ATP synthase 6 291 6.7E-90 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17290 d7b614222fecde6c29385f180de64c41 292 Gene3D G3DSA:3.40.1380.10 29 244 5.8E-67 T 29-03-2018 CWR56_RS07965 67de87016bc417934745b320d4251f8f 295 Gene3D G3DSA:3.40.50.300 1 241 3.3E-60 T 29-03-2018 CWR56_RS07965 67de87016bc417934745b320d4251f8f 295 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS07965 67de87016bc417934745b320d4251f8f 295 Pfam PF00005 ABC transporter 21 162 4.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07965 67de87016bc417934745b320d4251f8f 295 SMART SM00382 27 216 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07965 67de87016bc417934745b320d4251f8f 295 SUPERFAMILY SSF52540 4 224 3.84E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05160 0d0993e1237728409ad4186966de0d1d 325 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 5 323 24.638 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 CWR56_RS05160 0d0993e1237728409ad4186966de0d1d 325 Pfam PF03116 NQR2, RnfD, RnfE family 7 321 9.0E-115 T 29-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 CWR56_RS05160 0d0993e1237728409ad4186966de0d1d 325 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 10 322 3.3E-104 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 Gene3D G3DSA:2.30.40.10 1 65 1.9E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 Gene3D G3DSA:3.20.20.140 66 344 3.0E-96 T 29-03-2018 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 PIRSF PIRSF038994 1 377 1.1E-124 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 SUPERFAMILY SSF51338 2 50 1.9E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 SUPERFAMILY SSF51338 344 376 1.9E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 370 2.0E-101 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 SUPERFAMILY SSF51556 51 344 1.43E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS04595 5d3883fd73432ec1f08a588d90477a4e 377 Pfam PF01979 Amidohydrolase family 47 363 4.1E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS02450 dbb9d38eea95f69fd011578b41eee35b 205 SUPERFAMILY SSF103039 6 202 3.4E-47 T 29-03-2018 IPR028976 CheC-like domain CWR56_RS02450 dbb9d38eea95f69fd011578b41eee35b 205 Gene3D G3DSA:3.40.1550.10 3 203 3.9E-48 T 29-03-2018 IPR028976 CheC-like domain CWR56_RS02450 dbb9d38eea95f69fd011578b41eee35b 205 Pfam PF04509 CheC-like family 109 144 1.1E-8 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CWR56_RS02450 dbb9d38eea95f69fd011578b41eee35b 205 Pfam PF04509 CheC-like family 11 38 1.0E-7 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 17 458 2.9E-177 T 29-03-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 SUPERFAMILY SSF46548 8 150 8.37E-35 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 141 447 3.3E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 PRINTS PR00419 Adrenodoxin reductase family signature 164 177 8.9E-21 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 PRINTS PR00419 Adrenodoxin reductase family signature 283 297 8.9E-21 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 PRINTS PR00419 Adrenodoxin reductase family signature 316 329 8.9E-21 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 PRINTS PR00419 Adrenodoxin reductase family signature 141 163 8.9E-21 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 PRINTS PR00419 Adrenodoxin reductase family signature 207 217 8.9E-21 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 SUPERFAMILY SSF51971 139 392 2.71E-66 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Gene3D G3DSA:3.40.50.720 133 232 2.9E-16 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Gene3D G3DSA:1.10.1060.10 2 132 2.5E-41 T 29-03-2018 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Gene3D G3DSA:3.50.50.60 408 464 3.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 18 128 2.4E-44 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Gene3D G3DSA:3.50.50.60 233 306 1.6E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07280 b84d94ade6de3c6898bb5180ff46f8f2 464 Gene3D G3DSA:3.50.50.60 307 392 2.9E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 9.6E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 9.6E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 SUPERFAMILY SSF46785 3 75 3.11E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 70 3.7E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 Pfam PF07702 UTRA domain 92 223 8.3E-14 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 SUPERFAMILY SSF64288 58 230 9.89E-25 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 SMART SM00866 91 226 2.7E-10 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 Gene3D G3DSA:3.40.1410.10 70 232 4.1E-15 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 Gene3D G3DSA:1.10.10.10 2 69 4.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18215 9bcf620c5e039953e0c4a4baf9ea7fc9 233 SMART SM00345 11 70 4.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 Pfam PF02629 CoA binding domain 83 179 4.7E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 Gene3D G3DSA:3.40.50.720 78 209 5.7E-20 T 29-03-2018 CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 SMART SM00881 81 181 3.9E-22 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 210 36.231 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 Pfam PF06971 Putative DNA-binding protein N-terminus 6 54 1.1E-19 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 SUPERFAMILY SSF46785 10 80 5.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 SUPERFAMILY SSF51735 82 206 7.88E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS00840 ce26c6aee747ebfd27b25de61ea4ea54 210 Gene3D G3DSA:1.10.10.10 5 75 2.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 SUPERFAMILY SSF46785 2 73 1.33E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 260 8.9E-101 T 29-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 Gene3D G3DSA:1.10.10.10 1 73 5.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 Pfam PF00156 Phosphoribosyl transferase domain 112 246 2.5E-17 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 9.2E-30 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 12 73 3.0E-19 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 SUPERFAMILY SSF53271 84 238 2.84E-36 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS17540 aeabae7f8ad49ebebf5989cda61ea78c 292 Gene3D G3DSA:3.40.50.2020 74 262 4.0E-27 T 29-03-2018 CWR56_RS17750 b41920390affb4cb9e1c1269411a3267 256 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 251 1.5E-78 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWR56_RS17750 b41920390affb4cb9e1c1269411a3267 256 Pfam PF03309 Type III pantothenate kinase 2 204 3.5E-72 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWR56_RS17750 b41920390affb4cb9e1c1269411a3267 256 Gene3D G3DSA:3.30.420.40 89 256 3.1E-60 T 29-03-2018 CWR56_RS17750 b41920390affb4cb9e1c1269411a3267 256 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 36.798 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWR56_RS17750 b41920390affb4cb9e1c1269411a3267 256 SUPERFAMILY SSF53067 124 254 1.74E-37 T 29-03-2018 CWR56_RS17750 b41920390affb4cb9e1c1269411a3267 256 SUPERFAMILY SSF53067 1 122 2.37E-38 T 29-03-2018 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 8.8E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 Gene3D G3DSA:1.10.10.60 1 35 4.1E-13 T 29-03-2018 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 Gene3D G3DSA:1.10.260.40 36 75 3.9E-10 T 29-03-2018 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 SUPERFAMILY SSF46689 3 76 1.49E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS10640 ea236b12f72f30ee98b4a28508d4cee7 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CWR56_RS16255 825668f04b2fc2a92177062b2d2cd7d0 189 Pfam PF08241 Methyltransferase domain 55 128 1.5E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CWR56_RS16255 825668f04b2fc2a92177062b2d2cd7d0 189 SUPERFAMILY SSF53335 44 171 1.09E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS16255 825668f04b2fc2a92177062b2d2cd7d0 189 Gene3D G3DSA:3.40.50.150 26 188 9.6E-8 T 29-03-2018 CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 210 226 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 272 5.6E-91 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 Pfam PF01261 Xylose isomerase-like TIM barrel 23 234 2.5E-33 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 172 179 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 SMART SM00518 3 275 1.3E-98 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 Gene3D G3DSA:3.20.20.150 1 278 2.0E-53 T 29-03-2018 CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 SUPERFAMILY SSF51658 2 274 1.01E-88 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS02580 54e603d5e0fc2d4ef4c1948afda09995 278 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 275 40.989 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 Gene3D G3DSA:3.40.630.10 2 371 6.5E-63 T 29-03-2018 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 PIRSF PIRSF001123 99 184 3.0E-5 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 PIRSF PIRSF001123 229 371 1.2E-5 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 PIRSF PIRSF001123 4 99 1.0E-7 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 Pfam PF01546 Peptidase family M20/M25/M40 72 369 2.9E-21 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 SUPERFAMILY SSF55031 180 290 1.11E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 368 8.0E-121 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 SUPERFAMILY SSF53187 5 178 1.44E-60 T 29-03-2018 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 SUPERFAMILY SSF53187 289 370 1.44E-60 T 29-03-2018 CWR56_RS17560 7e11da0a137009a60733b33617e46cdc 371 Pfam PF07687 Peptidase dimerisation domain 184 274 7.2E-14 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 Gene3D G3DSA:3.30.360.10 165 318 1.9E-69 T 29-03-2018 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 SMART SM00846 3 155 2.3E-89 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 SUPERFAMILY SSF55347 155 317 1.34E-72 T 29-03-2018 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 1.9E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 1.9E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 1.9E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 1.9E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 1.9E-41 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 SUPERFAMILY SSF51735 3 171 3.3E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 1.0E-69 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 Gene3D G3DSA:3.40.50.720 1 164 5.5E-77 T 29-03-2018 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 105 2.7E-35 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 1.2E-138 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 PIRSF PIRSF000149 1 338 2.3E-140 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08500 a88e1b8f2d3cad84b214cc9f8c12e7d4 338 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS08165 1af471884934baeb8668ad10e96029ed 229 Gene3D G3DSA:3.20.20.70 1 229 1.3E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS08165 1af471884934baeb8668ad10e96029ed 229 Pfam PF02581 Thiamine monophosphate synthase 74 211 2.2E-23 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS08165 1af471884934baeb8668ad10e96029ed 229 Pfam PF02581 Thiamine monophosphate synthase 1 53 1.4E-6 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS08165 1af471884934baeb8668ad10e96029ed 229 SUPERFAMILY SSF51391 2 227 5.23E-31 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 SMART SM00363 341 402 2.7E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 Gene3D G3DSA:3.40.50.620 1 222 1.2E-62 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 400 1.1E-125 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 Pfam PF01479 S4 domain 346 386 1.7E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 SUPERFAMILY SSF52374 5 321 1.96E-91 T 29-03-2018 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 2.8E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 165 180 2.8E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 2.8E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 2.8E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 Gene3D G3DSA:3.10.290.10 315 402 1.5E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 SUPERFAMILY SSF55174 303 399 1.1E-18 T 29-03-2018 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 400 46.417 T 29-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 Gene3D G3DSA:1.10.240.10 223 314 2.6E-28 T 29-03-2018 CWR56_RS07200 4387db78298fa25bb20f03b1ef94e14e 402 Pfam PF00579 tRNA synthetases class I (W and Y) 35 322 6.0E-78 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS10555 7d2605ed2bfe8fc0e64ece7aaf77ab81 297 Gene3D G3DSA:1.10.530.10 135 290 4.2E-33 T 29-03-2018 CWR56_RS10555 7d2605ed2bfe8fc0e64ece7aaf77ab81 297 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 149 286 1.0E-20 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS10555 7d2605ed2bfe8fc0e64ece7aaf77ab81 297 SMART SM00047 131 290 5.6E-20 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS05575 2370ccd5322e8705b51234fe6dbd8391 178 PRINTS PR00502 NUDIX hydrolase family signature 71 85 4.5E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS05575 2370ccd5322e8705b51234fe6dbd8391 178 PRINTS PR00502 NUDIX hydrolase family signature 85 100 4.5E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS05575 2370ccd5322e8705b51234fe6dbd8391 178 SUPERFAMILY SSF55811 6 173 1.1E-47 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS05575 2370ccd5322e8705b51234fe6dbd8391 178 Gene3D G3DSA:3.90.79.10 2 178 3.8E-40 T 29-03-2018 CWR56_RS05575 2370ccd5322e8705b51234fe6dbd8391 178 Pfam PF00293 NUDIX domain 44 155 3.7E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS05575 2370ccd5322e8705b51234fe6dbd8391 178 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 Gene3D G3DSA:2.20.110.10 130 221 8.6E-25 T 29-03-2018 CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 Gene3D G3DSA:2.20.110.10 74 129 3.8E-18 T 29-03-2018 CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 Pfam PF02493 MORN repeat 92 110 1.2E-4 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 Pfam PF02493 MORN repeat 115 136 1.7E-8 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 Pfam PF02493 MORN repeat 161 182 0.0012 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 Pfam PF02493 MORN repeat 138 159 1.7E-6 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 SUPERFAMILY SSF82185 84 191 2.94E-30 T 29-03-2018 CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 SMART SM00698 113 134 7.5E-5 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 SMART SM00698 136 157 0.004 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 SMART SM00698 90 111 7.0E-4 T 29-03-2018 IPR003409 MORN motif CWR56_RS12090 76d2fdff743c83480ea0a0ee9ec11d44 222 SMART SM00698 159 180 0.38 T 29-03-2018 IPR003409 MORN motif CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Pfam PF03484 tRNA synthetase B5 domain 414 478 1.1E-17 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Gene3D G3DSA:2.40.50.140 54 161 4.2E-37 T 29-03-2018 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Gene3D G3DSA:3.30.56.10 409 482 3.0E-21 T 29-03-2018 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SMART SM00896 702 795 6.2E-45 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SUPERFAMILY SSF55681 474 687 1.29E-44 T 29-03-2018 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Pfam PF01588 Putative tRNA binding domain 46 129 2.3E-17 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Gene3D G3DSA:3.30.930.10 492 692 3.8E-42 T 29-03-2018 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 789 42.49 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Pfam PF03483 B3/4 domain 220 389 5.8E-67 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SUPERFAMILY SSF54991 698 795 5.89E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Gene3D G3DSA:3.30.56.10 1 53 2.8E-13 T 29-03-2018 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Pfam PF03147 Ferredoxin-fold anticodon binding domain 702 795 3.6E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 795 1.9E-259 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SUPERFAMILY SSF56037 208 403 6.28E-69 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SMART SM00874 409 478 3.3E-24 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SUPERFAMILY SSF46955 409 482 1.74E-16 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SMART SM00873 219 392 1.3E-85 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Gene3D G3DSA:3.50.40.10 202 403 1.2E-74 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 SUPERFAMILY SSF50249 35 199 3.43E-42 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS03365 d6d049664b09bd684339562972c3b68e 797 Gene3D G3DSA:3.30.70.380 698 795 7.1E-29 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 Gene3D G3DSA:3.10.290.10 1 60 6.5E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 PIRSF PIRSF005578 1 263 4.5E-103 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 Pfam PF01728 FtsJ-like methyltransferase 59 240 7.8E-21 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 Gene3D G3DSA:3.40.50.150 62 270 9.3E-58 T 29-03-2018 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 Pfam PF01479 S4 domain 4 46 5.1E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 SMART SM00363 3 68 1.8E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 SUPERFAMILY SSF53335 56 245 9.14E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 4 235 1.3E-86 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CWR56_RS05515 5774ba9f7a952a6ec071d4b624f6e73d 270 SUPERFAMILY SSF55174 3 60 2.36E-12 T 29-03-2018 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SMART SM00267 408 572 3.6E-42 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Gene3D G3DSA:1.25.40.10 171 213 0.049 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Gene3D G3DSA:1.25.40.10 33 170 4.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SUPERFAMILY SSF55073 427 571 5.26E-36 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 420 571 1.9E-39 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Gene3D G3DSA:3.30.70.270 413 572 9.1E-42 T 29-03-2018 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Pfam PF00990 Diguanylate cyclase, GGDEF domain 423 568 3.3E-35 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Gene3D G3DSA:1.10.150.200 290 346 6.6E-7 T 29-03-2018 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SUPERFAMILY SSF48452 286 394 3.79E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SUPERFAMILY SSF48452 123 233 3.79E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Gene3D G3DSA:1.25.40.10 214 289 4.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SMART SM00028 120 153 45.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SMART SM00028 288 321 0.81 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 SMART SM00028 202 235 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS05400 583ceb46c0160258559cd8129a0f5526 572 Pfam PF13176 Tetratricopeptide repeat 204 223 0.0054 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS03905 6b8b71bbb0a17f0e26181b9b3bd90054 397 Pfam PF02515 CoA-transferase family III 6 372 1.9E-124 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CWR56_RS03905 6b8b71bbb0a17f0e26181b9b3bd90054 397 SUPERFAMILY SSF89796 4 397 2.22E-126 T 29-03-2018 IPR023606 CoA-transferase family III domain CWR56_RS03905 6b8b71bbb0a17f0e26181b9b3bd90054 397 Gene3D G3DSA:3.40.50.10540 1 397 3.3E-139 T 29-03-2018 IPR023606 CoA-transferase family III domain CWR56_RS17475 27c2a69e17c26943602219c9878b7a8f 260 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 12 93 2.7E-30 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal CWR56_RS17475 27c2a69e17c26943602219c9878b7a8f 260 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 182 193 2.8E-5 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CWR56_RS17475 27c2a69e17c26943602219c9878b7a8f 260 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 114 131 2.8E-5 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CWR56_RS17475 27c2a69e17c26943602219c9878b7a8f 260 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 171 181 2.8E-5 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CWR56_RS17475 27c2a69e17c26943602219c9878b7a8f 260 Pfam PF01478 Type IV leader peptidase family 105 214 2.2E-17 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CWR56_RS00790 936c668a19bfa8f5979acbc0245cd1a7 227 Gene3D G3DSA:3.40.50.300 1 226 3.2E-64 T 29-03-2018 CWR56_RS00790 936c668a19bfa8f5979acbc0245cd1a7 227 Pfam PF00005 ABC transporter 23 169 5.4E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00790 936c668a19bfa8f5979acbc0245cd1a7 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS00790 936c668a19bfa8f5979acbc0245cd1a7 227 SMART SM00382 32 219 2.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00790 936c668a19bfa8f5979acbc0245cd1a7 227 SUPERFAMILY SSF52540 3 223 6.21E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 SUPERFAMILY SSF51735 3 109 3.1E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 Pfam PF13241 Putative NAD(P)-binding 6 112 2.3E-26 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 Pfam PF14824 Sirohaem biosynthesis protein central 116 142 2.4E-10 T 29-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 SUPERFAMILY SSF75615 111 180 9.94E-18 T 29-03-2018 CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 Gene3D G3DSA:3.30.160.110 117 143 1.6E-13 T 29-03-2018 CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 Gene3D G3DSA:3.40.50.720 2 116 5.6E-19 T 29-03-2018 CWR56_RS17030 52cef999a2f462d6d34019dbb9aff523 192 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 184 9.4E-34 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS10735 50daf123e41c647dcb90559d68d0dd94 260 Gene3D G3DSA:3.30.460.10 10 142 7.2E-20 T 29-03-2018 CWR56_RS10735 50daf123e41c647dcb90559d68d0dd94 260 Gene3D G3DSA:1.20.120.330 143 260 8.6E-20 T 29-03-2018 CWR56_RS10735 50daf123e41c647dcb90559d68d0dd94 260 Pfam PF04439 Streptomycin adenylyltransferase 3 239 1.3E-10 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase CWR56_RS10735 50daf123e41c647dcb90559d68d0dd94 260 SUPERFAMILY SSF81301 3 125 1.86E-16 T 29-03-2018 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 Gene3D G3DSA:3.30.465.10 97 239 4.0E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 Gene3D G3DSA:3.30.43.10 1 96 9.3E-21 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 SUPERFAMILY SSF56176 5 219 5.61E-67 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 Pfam PF01565 FAD binding domain 44 181 2.0E-38 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 462 1.8E-62 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 Gene3D G3DSA:1.10.45.10 423 462 2.3E-14 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CWR56_RS05335 5d5b9e1c7526fe0dbd79af3fbcaf5f96 463 SUPERFAMILY SSF55103 223 463 1.8E-55 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CWR56_RS01225 9e91f7d2a49624afd8b89084597c1385 331 SUPERFAMILY SSF55729 160 326 7.95E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS01225 9e91f7d2a49624afd8b89084597c1385 331 Gene3D G3DSA:3.40.630.30 158 321 2.3E-24 T 29-03-2018 CWR56_RS01225 9e91f7d2a49624afd8b89084597c1385 331 Gene3D G3DSA:3.40.630.30 8 157 4.3E-12 T 29-03-2018 CWR56_RS01225 9e91f7d2a49624afd8b89084597c1385 331 Pfam PF02388 FemAB family 211 317 1.1E-8 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWR56_RS06915 32f80a3e8481836780c92fc475b523b9 1013 SUPERFAMILY SSF56601 61 387 1.78E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS06915 32f80a3e8481836780c92fc475b523b9 1013 Pfam PF00144 Beta-lactamase 66 387 1.2E-58 T 29-03-2018 IPR001466 Beta-lactamase-related CWR56_RS06915 32f80a3e8481836780c92fc475b523b9 1013 Gene3D G3DSA:3.40.710.10 55 400 2.2E-72 T 29-03-2018 CWR56_RS06915 32f80a3e8481836780c92fc475b523b9 1013 Pfam PF04122 Putative cell wall binding repeat 2 915 1001 1.7E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS06915 32f80a3e8481836780c92fc475b523b9 1013 Pfam PF04122 Putative cell wall binding repeat 2 719 802 1.6E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS06915 32f80a3e8481836780c92fc475b523b9 1013 Pfam PF04122 Putative cell wall binding repeat 2 817 907 2.0E-17 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS01135 17399d5202b53eb74fdcba0c18eb8d38 327 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 310 2.6E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS01135 17399d5202b53eb74fdcba0c18eb8d38 327 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 324 3.8E-151 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CWR56_RS01135 17399d5202b53eb74fdcba0c18eb8d38 327 Gene3D G3DSA:3.40.50.720 1 191 2.8E-36 T 29-03-2018 CWR56_RS01135 17399d5202b53eb74fdcba0c18eb8d38 327 SUPERFAMILY SSF51735 1 323 3.94E-97 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS01135 17399d5202b53eb74fdcba0c18eb8d38 327 Gene3D G3DSA:3.90.25.10 192 327 2.1E-48 T 29-03-2018 CWR56_RS05365 3b5df0cbd4cadfd83b536e6df27d283d 340 SUPERFAMILY SSF53659 1 331 2.14E-98 T 29-03-2018 CWR56_RS05365 3b5df0cbd4cadfd83b536e6df27d283d 340 Pfam PF02504 Fatty acid synthesis protein 1 319 4.0E-109 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CWR56_RS05365 3b5df0cbd4cadfd83b536e6df27d283d 340 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 332 4.4E-111 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWR56_RS05365 3b5df0cbd4cadfd83b536e6df27d283d 340 PIRSF PIRSF002465 1 335 4.8E-120 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWR56_RS05365 3b5df0cbd4cadfd83b536e6df27d283d 340 Gene3D G3DSA:3.40.718.10 1 332 2.3E-106 T 29-03-2018 CWR56_RS05365 3b5df0cbd4cadfd83b536e6df27d283d 340 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 138.882 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWR56_RS00530 32199f3123bb17d5ec3214c767db1148 300 PIRSF PIRSF000428 1 300 8.2E-87 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS00530 32199f3123bb17d5ec3214c767db1148 300 SUPERFAMILY SSF53659 2 298 4.93E-64 T 29-03-2018 CWR56_RS00530 32199f3123bb17d5ec3214c767db1148 300 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 74 1.1E-7 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS00530 32199f3123bb17d5ec3214c767db1148 300 Pfam PF01515 Phosphate acetyl/butaryl transferase 77 292 5.4E-51 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS00530 32199f3123bb17d5ec3214c767db1148 300 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 296 5.9E-128 T 29-03-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 CWR56_RS00530 32199f3123bb17d5ec3214c767db1148 300 Gene3D G3DSA:3.40.50.10750 114 269 5.7E-39 T 29-03-2018 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 Gene3D G3DSA:3.10.20.10 31 87 1.2E-11 T 29-03-2018 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 Pfam PF02634 FdhD/NarQ family 29 249 3.4E-63 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 PIRSF PIRSF015626 3 252 9.0E-62 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 7 250 27.594 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 26 250 1.3E-57 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 Gene3D G3DSA:3.40.140.10 115 252 8.0E-45 T 29-03-2018 CWR56_RS16680 4b2d160f06abd0b8e3b35cd8462d85b9 252 SUPERFAMILY SSF53927 11 250 4.21E-64 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS04680 047a0392f48b3ffa320ca0889d1f6a36 242 SUPERFAMILY SSF161098 2 231 4.84E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04680 047a0392f48b3ffa320ca0889d1f6a36 242 Gene3D G3DSA:1.10.3720.10 1 239 2.1E-34 T 29-03-2018 CWR56_RS04680 047a0392f48b3ffa320ca0889d1f6a36 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 59 229 2.2E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 450 40.437 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 SUPERFAMILY SSF53448 1 252 5.42E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Gene3D G3DSA:2.160.10.10 244 308 1.7E-16 T 29-03-2018 CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Gene3D G3DSA:2.160.10.10 309 445 1.4E-34 T 29-03-2018 CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Gene3D G3DSA:3.90.550.10 1 243 1.4E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 397 426 0.15 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 SUPERFAMILY SSF51161 253 445 1.95E-46 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Pfam PF00483 Nucleotidyl transferase 4 213 2.6E-24 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 316 349 1.5E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 283 314 4.1E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS17530 5fb8106883a99c50484f89f66caaef1a 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 452 6.8E-177 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CWR56_RS03740 4c059e4f003e5f5e73ed566a28947b27 111 Gene3D G3DSA:3.30.750.24 2 111 2.2E-19 T 29-03-2018 IPR002645 STAS domain CWR56_RS03740 4c059e4f003e5f5e73ed566a28947b27 111 Pfam PF01740 STAS domain 17 107 5.1E-17 T 29-03-2018 IPR002645 STAS domain CWR56_RS03740 4c059e4f003e5f5e73ed566a28947b27 111 SUPERFAMILY SSF52091 8 109 3.34E-25 T 29-03-2018 IPR002645 STAS domain CWR56_RS03740 4c059e4f003e5f5e73ed566a28947b27 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 18 106 4.3E-26 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CWR56_RS03740 4c059e4f003e5f5e73ed566a28947b27 111 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 6 108 3.2E-37 T 29-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 SMART SM01133 3 213 3.4E-86 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 5 210 5.9E-75 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 SUPERFAMILY SSF51569 3 213 7.95E-80 T 29-03-2018 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 PIRSF PIRSF001357 1 219 6.3E-80 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 2 215 34.576 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 Pfam PF01791 DeoC/LacD family aldolase 6 199 1.8E-20 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR56_RS07085 cead15c672c89cd0b3f47046c3c58c96 219 Gene3D G3DSA:3.20.20.70 1 217 3.1E-89 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS05165 70cf1ed5dc401953d54642a69ccd147b 189 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 184 1.3E-33 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CWR56_RS05165 70cf1ed5dc401953d54642a69ccd147b 189 PIRSF PIRSF006091 1 189 6.1E-43 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CWR56_RS05165 70cf1ed5dc401953d54642a69ccd147b 189 SMART SM00900 94 183 2.9E-19 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CWR56_RS05165 70cf1ed5dc401953d54642a69ccd147b 189 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 1 185 21.692 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CWR56_RS05165 70cf1ed5dc401953d54642a69ccd147b 189 Pfam PF04205 FMN-binding domain 94 180 2.4E-17 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CWR56_RS06495 8a3f6de91c1096a6cacffe00c67496a9 386 Pfam PF05684 Protein of unknown function (DUF819) 14 382 1.3E-45 T 29-03-2018 IPR008537 Protein of unknown function DUF819 CWR56_RS16740 0d63b6f6d81325c4521fb885a80d3794 438 Gene3D G3DSA:3.30.565.10 294 438 4.3E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16740 0d63b6f6d81325c4521fb885a80d3794 438 Pfam PF14501 GHKL domain 330 435 6.2E-24 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS16740 0d63b6f6d81325c4521fb885a80d3794 438 SUPERFAMILY SSF55874 302 435 1.32E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 SUPERFAMILY SSF53850 50 352 2.64E-77 T 29-03-2018 CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 SUPERFAMILY SSF53850 412 550 2.64E-77 T 29-03-2018 CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 Gene3D G3DSA:3.40.190.10 158 289 9.5E-26 T 29-03-2018 CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 488 8.8E-49 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 Gene3D G3DSA:3.90.76.10 66 157 5.9E-19 T 29-03-2018 CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 Gene3D G3DSA:3.10.105.10 290 534 1.1E-37 T 29-03-2018 CWR56_RS05125 4aa9a6f03c5b5176e919ab3628955558 571 PIRSF PIRSF002741 1 569 5.4E-65 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWR56_RS03045 e99d42c5cdc4d57ce2172302f733fd7b 308 SUPERFAMILY SSF52540 3 223 2.38E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03045 e99d42c5cdc4d57ce2172302f733fd7b 308 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS03045 e99d42c5cdc4d57ce2172302f733fd7b 308 Gene3D G3DSA:3.40.50.300 1 246 3.9E-57 T 29-03-2018 CWR56_RS03045 e99d42c5cdc4d57ce2172302f733fd7b 308 SMART SM00382 29 213 2.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03045 e99d42c5cdc4d57ce2172302f733fd7b 308 Pfam PF00005 ABC transporter 21 161 1.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS17070 92bd0a11781ab06ee6355c9e362755b7 250 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 209 4.7E-42 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17070 92bd0a11781ab06ee6355c9e362755b7 250 Gene3D G3DSA:3.30.950.10 123 245 1.9E-27 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17070 92bd0a11781ab06ee6355c9e362755b7 250 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17070 92bd0a11781ab06ee6355c9e362755b7 250 Gene3D G3DSA:3.40.1010.10 1 122 3.7E-28 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17070 92bd0a11781ab06ee6355c9e362755b7 250 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 4 249 2.7E-106 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CWR56_RS17070 92bd0a11781ab06ee6355c9e362755b7 250 SUPERFAMILY SSF53790 1 249 5.37E-67 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 SMART SM00829 8 343 1.1E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 Gene3D G3DSA:3.90.180.10 1 152 3.6E-47 T 29-03-2018 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 1.2E-32 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 Gene3D G3DSA:3.40.50.10730 153 291 1.5E-28 T 29-03-2018 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 SUPERFAMILY SSF51735 133 312 1.13E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 Pfam PF00107 Zinc-binding dehydrogenase 170 290 1.3E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 SUPERFAMILY SSF50129 2 168 5.37E-50 T 29-03-2018 IPR011032 GroES-like CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 Gene3D G3DSA:3.90.180.10 292 346 4.6E-7 T 29-03-2018 CWR56_RS11550 447171b05a17132bf51d8a94d7e1c7a1 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR56_RS12335 e68b89c412e3b8b6a770731e52a0c3d6 447 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 2 372 1.1E-80 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CWR56_RS12335 e68b89c412e3b8b6a770731e52a0c3d6 447 PIRSF PIRSF029895 1 383 1.4E-73 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CWR56_RS12335 e68b89c412e3b8b6a770731e52a0c3d6 447 Pfam PF06898 Putative stage IV sporulation protein YqfD 4 370 2.8E-96 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 Gene3D G3DSA:2.30.40.10 1 64 8.1E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 SUPERFAMILY SSF51338 2 52 1.81E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 SUPERFAMILY SSF51338 381 397 1.81E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 Gene3D G3DSA:3.20.20.140 65 273 1.7E-57 T 29-03-2018 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 Gene3D G3DSA:3.20.20.140 274 422 6.0E-47 T 29-03-2018 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 SUPERFAMILY SSF51556 53 381 2.31E-108 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 452 1.8E-178 T 29-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 SUPERFAMILY SSF51338 348 453 9.3E-31 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09995 a0b4f6c68771e1d49393292dabbb3e5f 456 Pfam PF01979 Amidohydrolase family 49 434 1.0E-33 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS02320 2ec585743055424725d544220abbad33 432 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 319 399 5.7E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS02320 2ec585743055424725d544220abbad33 432 Gene3D G3DSA:3.20.20.70 97 425 1.0E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS02320 2ec585743055424725d544220abbad33 432 Pfam PF13394 4Fe-4S single cluster domain 100 205 3.7E-12 T 29-03-2018 CWR56_RS02320 2ec585743055424725d544220abbad33 432 Pfam PF13186 Iron-sulfur cluster-binding domain 319 388 6.4E-11 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS02320 2ec585743055424725d544220abbad33 432 Pfam PF04055 Radical SAM superfamily 103 245 6.3E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS02320 2ec585743055424725d544220abbad33 432 SUPERFAMILY SSF102114 98 393 2.62E-51 T 29-03-2018 CWR56_RS02320 2ec585743055424725d544220abbad33 432 PIRSF PIRSF037420 293 428 1.2E-4 T 29-03-2018 CWR56_RS02320 2ec585743055424725d544220abbad33 432 PIRSF PIRSF037420 83 321 1.5E-36 T 29-03-2018 CWR56_RS00855 a7702ac47f8b715b739d27bc84eae086 355 Gene3D G3DSA:3.60.21.10 30 354 9.6E-49 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS00855 a7702ac47f8b715b739d27bc84eae086 355 SMART SM00854 54 284 3.5E-95 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CWR56_RS00855 a7702ac47f8b715b739d27bc84eae086 355 SUPERFAMILY SSF56300 53 325 1.92E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS00855 a7702ac47f8b715b739d27bc84eae086 355 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 54 283 1.1E-62 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CWR56_RS18005 d03e15b38b145e1beb4e00c582893c39 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 79 180 5.2E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS18005 d03e15b38b145e1beb4e00c582893c39 216 Gene3D G3DSA:3.40.50.1000 2 32 0.0055 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS18005 d03e15b38b145e1beb4e00c582893c39 216 Gene3D G3DSA:1.10.150.240 33 74 6.6E-19 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR56_RS18005 d03e15b38b145e1beb4e00c582893c39 216 Gene3D G3DSA:3.40.50.1000 75 216 8.1E-29 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS18005 d03e15b38b145e1beb4e00c582893c39 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 186 9.1E-32 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS18005 d03e15b38b145e1beb4e00c582893c39 216 SUPERFAMILY SSF56784 3 215 1.1E-56 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS10510 196e802af71386df9198064da4ac3571 140 Gene3D G3DSA:3.30.70.20 62 86 1.1E-9 T 29-03-2018 CWR56_RS10510 196e802af71386df9198064da4ac3571 140 Pfam PF13247 4Fe-4S dicluster domain 48 139 1.7E-16 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS10510 196e802af71386df9198064da4ac3571 140 Gene3D G3DSA:3.30.70.20 1 19 0.012 T 29-03-2018 CWR56_RS10510 196e802af71386df9198064da4ac3571 140 Gene3D G3DSA:3.30.70.20 105 140 6.2E-9 T 29-03-2018 CWR56_RS10510 196e802af71386df9198064da4ac3571 140 SUPERFAMILY SSF54862 5 138 5.23E-36 T 29-03-2018 CWR56_RS10510 196e802af71386df9198064da4ac3571 140 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS10510 196e802af71386df9198064da4ac3571 140 Gene3D G3DSA:3.30.70.20 87 104 3.1E-5 T 29-03-2018 CWR56_RS10510 196e802af71386df9198064da4ac3571 140 Gene3D G3DSA:3.30.70.20 20 61 1.2E-7 T 29-03-2018 CWR56_RS16560 38e8442b38207daa34d9c04ceb90836e 290 Gene3D G3DSA:3.30.420.40 5 165 3.1E-6 T 29-03-2018 CWR56_RS05420 fe90e52dac1ac5339de1b9b83028488c 442 PIRSF PIRSF006060 3 441 2.8E-77 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS05420 fe90e52dac1ac5339de1b9b83028488c 442 Pfam PF13520 Amino acid permease 13 401 1.1E-53 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS06715 1949dd9974254a66221de1c8c826025d 261 Pfam PF12746 GNAT acetyltransferase 112 258 5.9E-10 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like CWR56_RS06715 1949dd9974254a66221de1c8c826025d 261 Gene3D G3DSA:3.40.630.30 122 258 1.7E-11 T 29-03-2018 CWR56_RS06715 1949dd9974254a66221de1c8c826025d 261 SUPERFAMILY SSF55729 128 257 5.6E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 SUPERFAMILY SSF52172 7 136 1.38E-31 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 Gene3D G3DSA:1.10.10.10 160 269 1.5E-54 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 163 266 1.9E-46 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 SUPERFAMILY SSF46894 156 270 1.79E-49 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 Gene3D G3DSA:3.40.50.2300 6 159 6.4E-30 T 29-03-2018 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 7 271 6.0E-125 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 SMART SM00448 9 124 3.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 171 270 1.0E-53 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 PIRSF PIRSF002937 4 273 1.3E-134 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CWR56_RS05545 3ee9696e0120d4dbc11c65d9e42c9857 274 Pfam PF00072 Response regulator receiver domain 11 124 1.4E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 2 236 43.979 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 157 8.5E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 6 87 4.1E-30 T 29-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 175 203 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 Gene3D G3DSA:2.160.10.10 86 238 2.3E-43 T 29-03-2018 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 SUPERFAMILY SSF51161 86 226 1.07E-48 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 7 237 9.0E-104 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 Gene3D G3DSA:3.30.70.250 5 85 1.6E-28 T 29-03-2018 CWR56_RS16215 36fdad296bdbd8bc78ccafd1101e27d2 238 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 166 200 2.5E-11 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS11560 e0a506b7464cf169630adfd6dbea2a0f 91 SUPERFAMILY SSF52794 1 89 2.88E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11560 e0a506b7464cf169630adfd6dbea2a0f 91 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 76 1.5E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11560 e0a506b7464cf169630adfd6dbea2a0f 91 Gene3D G3DSA:3.40.50.2300 1 91 3.5E-20 T 29-03-2018 CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 SUPERFAMILY SSF88946 11 92 1.44E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 Pfam PF04542 Sigma-70 region 2 18 80 4.5E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 SUPERFAMILY SSF88659 98 158 4.3E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 Gene3D G3DSA:1.10.1740.10 3 101 5.0E-15 T 29-03-2018 CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 157 1.0E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 Gene3D G3DSA:1.10.10.10 102 160 2.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07390 a2a40f0b85e2cd835a2706156b6c7b41 160 Pfam PF08281 Sigma-70, region 4 103 154 1.5E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03755 688be29d67354b25d78682591ce6d80e 145 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 21 138 1.5E-40 T 29-03-2018 IPR005562 SpoVA CWR56_RS03755 688be29d67354b25d78682591ce6d80e 145 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 4 142 1.8E-57 T 29-03-2018 IPR014203 Sporulation stage V, protein AC CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 PIRSF PIRSF005814 1 554 1.7E-197 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 PIRSF PIRSF005814 517 636 1.0 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 405 421 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 SUPERFAMILY SSF48334 21 283 2.35E-17 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 Pfam PF00488 MutS domain V 326 506 3.7E-33 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 SMART SM00534 323 508 3.5E-60 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 SUPERFAMILY SSF52540 289 507 1.29E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 Gene3D G3DSA:3.40.50.300 288 511 4.9E-29 T 29-03-2018 CWR56_RS10335 bf97859fd320e132f4bcfc7160131e0b 636 SMART SM00533 9 311 1.0E-9 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 3.3E-26 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 SUPERFAMILY SSF55681 117 422 1.7E-101 T 29-03-2018 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 Gene3D G3DSA:1.10.287.40 2 105 5.0E-22 T 29-03-2018 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 7.1E-170 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 3.2E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 3.2E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 3.2E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 3.2E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 3.2E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 SUPERFAMILY SSF46589 1 113 2.88E-26 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 42.292 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 400 1.3E-36 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 Gene3D G3DSA:3.30.930.10 106 423 4.3E-96 T 29-03-2018 CWR56_RS14420 d4ce2e5bca7b4750697f1c4b096d8640 423 PIRSF PIRSF001529 1 423 8.1E-182 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 SUPERFAMILY SSF51735 102 281 2.85E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 280 9.6E-56 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 SUPERFAMILY SSF52283 1 135 6.43E-31 T 29-03-2018 CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 302 5.4E-33 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 Gene3D G3DSA:3.40.50.720 109 282 3.6E-49 T 29-03-2018 CWR56_RS04515 e3772c3c36818180808754ec14b61d3e 313 Gene3D G3DSA:3.40.50.720 1 108 2.9E-29 T 29-03-2018 CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 SMART SM00863 180 222 1.2E-11 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 SUPERFAMILY SSF50447 2 71 1.84E-13 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 Pfam PF02272 DHHA1 domain 270 389 8.5E-14 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 Gene3D G3DSA:3.30.980.10 85 238 1.3E-34 T 29-03-2018 CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 SUPERFAMILY SSF55186 88 229 6.54E-32 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 Pfam PF01411 tRNA synthetases class II (A) 18 87 5.4E-7 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CWR56_RS10425 ade8335a698cdfe5bc8219e1b93f6e53 399 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 180 222 5.8E-8 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR56_RS02560 f90c78580c90c4b047ddce862467c2f0 251 SUPERFAMILY SSF51658 44 248 2.05E-24 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS02560 f90c78580c90c4b047ddce862467c2f0 251 Gene3D G3DSA:3.20.20.150 6 249 7.3E-20 T 29-03-2018 CWR56_RS02560 f90c78580c90c4b047ddce862467c2f0 251 Pfam PF01261 Xylose isomerase-like TIM barrel 33 210 1.3E-10 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS05305 958d58eafd87534ebcbc747a80a0ab2d 190 Gene3D G3DSA:1.10.443.10 5 184 4.8E-26 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS05305 958d58eafd87534ebcbc747a80a0ab2d 190 Pfam PF00589 Phage integrase family 11 177 5.2E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS05305 958d58eafd87534ebcbc747a80a0ab2d 190 SUPERFAMILY SSF56349 5 183 1.12E-28 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS06790 a8f0dc2262077167748e5027098a19a7 239 Pfam PF01522 Polysaccharide deacetylase 47 170 4.1E-38 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS06790 a8f0dc2262077167748e5027098a19a7 239 Gene3D G3DSA:3.20.20.370 29 239 1.2E-60 T 29-03-2018 CWR56_RS06790 a8f0dc2262077167748e5027098a19a7 239 SUPERFAMILY SSF88713 35 238 6.23E-66 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS08895 c2d4e42de3accc7d7e228a15c9571684 102 Gene3D G3DSA:2.30.110.10 1 77 6.1E-10 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS08895 c2d4e42de3accc7d7e228a15c9571684 102 SUPERFAMILY SSF50475 2 72 5.05E-13 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS08895 c2d4e42de3accc7d7e228a15c9571684 102 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 2 71 6.0E-6 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 221 7.8E-70 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 231 102.836 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 SUPERFAMILY SSF75217 1 228 7.85E-97 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 Gene3D G3DSA:1.10.1270.20 171 231 9.9E-31 T 29-03-2018 CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 Gene3D G3DSA:3.40.1280.10 1 170 3.5E-77 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 PIRSF PIRSF000386 1 231 4.7E-103 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR56_RS05810 c0914a7cf65098553fb185b55501240b 231 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 229 4.5E-100 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR56_RS14715 a000f6423bc8b646cc166ac563557101 187 Pfam PF01991 ATP synthase (E/31 kDa) subunit 11 174 2.8E-11 T 29-03-2018 IPR002842 ATPase, V1/A1 complex, subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14715 a000f6423bc8b646cc166ac563557101 187 SUPERFAMILY SSF160527 81 187 8.63E-20 T 29-03-2018 CWR56_RS14715 a000f6423bc8b646cc166ac563557101 187 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 187 13.108 T 29-03-2018 IPR002842 ATPase, V1/A1 complex, subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14715 a000f6423bc8b646cc166ac563557101 187 Gene3D G3DSA:3.30.980.20 17 105 0.0035 T 29-03-2018 CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 SUPERFAMILY SSF53474 7 290 5.81E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 PIRSF PIRSF005539 1 293 4.2E-94 T 29-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 Pfam PF00561 alpha/beta hydrolase fold 28 277 2.1E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 Gene3D G3DSA:3.40.50.1820 1 292 2.4E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 30 38 5.1E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 100 114 5.1E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 57 68 5.1E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS15160 e43f8b225c611e519e9b8d46f1236293 293 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 3 290 3.0E-86 T 29-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS15325 304e7945ea543ac76dd0aba4cfc907f7 687 Gene3D G3DSA:1.20.1380.10 592 683 2.2E-10 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 CWR56_RS15325 304e7945ea543ac76dd0aba4cfc907f7 687 Pfam PF07510 Protein of unknown function (DUF1524) 407 547 4.8E-33 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 CWR56_RS15325 304e7945ea543ac76dd0aba4cfc907f7 687 Pfam PF03235 Protein of unknown function DUF262 14 218 4.5E-35 T 29-03-2018 IPR004919 Domain of unknown function DUF262 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 SUPERFAMILY SSF51395 1 368 1.44E-105 T 29-03-2018 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 336 2.2E-77 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 Gene3D G3DSA:3.50.50.60 482 612 9.0E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 Gene3D G3DSA:3.20.20.70 1 379 5.0E-112 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 Gene3D G3DSA:3.50.50.60 380 481 2.3E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 SUPERFAMILY SSF51905 360 637 2.91E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 380 604 1.9E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 499 523 2.8E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 380 402 2.8E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 599 621 2.2E-18 T 29-03-2018 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 481 2.2E-18 T 29-03-2018 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 400 2.2E-18 T 29-03-2018 CWR56_RS13710 44dea96e9e9c026611e46802d55efe7a 640 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 503 521 2.2E-18 T 29-03-2018 CWR56_RS14585 bb043144c6276e2edbc1a6a5d0775a91 324 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 14 247 3.0E-72 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 CWR56_RS14585 bb043144c6276e2edbc1a6a5d0775a91 324 Pfam PF03812 2-keto-3-deoxygluconate permease 3 307 9.1E-119 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 CWR56_RS17350 ac360ea6f0c036e8f204a42fa2b99662 150 PIRSF PIRSF005384 1 148 1.7E-59 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS17350 ac360ea6f0c036e8f204a42fa2b99662 150 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 4 146 1.2E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS17350 ac360ea6f0c036e8f204a42fa2b99662 150 SUPERFAMILY SSF89623 1 145 1.44E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS17350 ac360ea6f0c036e8f204a42fa2b99662 150 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 145 4.9E-53 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CWR56_RS17350 ac360ea6f0c036e8f204a42fa2b99662 150 Pfam PF02502 Ribose/Galactose Isomerase 3 141 4.4E-56 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS17350 ac360ea6f0c036e8f204a42fa2b99662 150 Gene3D G3DSA:3.40.1400.10 1 150 5.0E-67 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR56_RS03260 3009d6c04a1acf97ba88a3c64e2f9b9e 421 Pfam PF07690 Major Facilitator Superfamily 33 276 4.3E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS03260 3009d6c04a1acf97ba88a3c64e2f9b9e 421 SUPERFAMILY SSF103473 19 417 1.27E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS03260 3009d6c04a1acf97ba88a3c64e2f9b9e 421 Gene3D G3DSA:1.20.1250.20 15 217 3.8E-29 T 29-03-2018 CWR56_RS03260 3009d6c04a1acf97ba88a3c64e2f9b9e 421 Gene3D G3DSA:1.20.1250.20 218 420 4.7E-25 T 29-03-2018 CWR56_RS03295 538f1aa0f30b5c51ed1a80fb239f2a80 176 SUPERFAMILY SSF46785 3 159 7.06E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03295 538f1aa0f30b5c51ed1a80fb239f2a80 176 Gene3D G3DSA:1.10.10.10 8 158 2.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08805 7fba1948b4a7946415750f59a7863547 296 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 41 290 1.0E-75 T 29-03-2018 CWR56_RS08805 7fba1948b4a7946415750f59a7863547 296 PIRSF PIRSF000450 1 296 1.7E-103 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CWR56_RS08805 7fba1948b4a7946415750f59a7863547 296 SUPERFAMILY SSF52317 40 292 8.14E-77 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS08805 7fba1948b4a7946415750f59a7863547 296 Gene3D G3DSA:3.40.50.880 38 296 3.1E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS08805 7fba1948b4a7946415750f59a7863547 296 Pfam PF04204 Homoserine O-succinyltransferase 3 294 6.0E-103 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CWR56_RS00150 82fb0ef85ec1381930a42e811ecd9359 61 SUPERFAMILY SSF57716 5 61 5.27E-22 T 29-03-2018 CWR56_RS00150 82fb0ef85ec1381930a42e811ecd9359 61 Gene3D G3DSA:4.10.830.10 1 61 7.7E-23 T 29-03-2018 CWR56_RS00150 82fb0ef85ec1381930a42e811ecd9359 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 8.1E-25 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00150 82fb0ef85ec1381930a42e811ecd9359 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.849 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z CWR56_RS00150 82fb0ef85ec1381930a42e811ecd9359 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS15305 65b5d2af30cd89e3dd98f300b5d12264 259 Pfam PF03609 PTS system sorbose-specific iic component 5 236 1.8E-72 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWR56_RS06250 a281872e5a87ff9961ad80a94b894237 110 Gene3D G3DSA:1.10.10.10 1 94 4.6E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06250 a281872e5a87ff9961ad80a94b894237 110 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 1.0E-19 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR56_RS06250 a281872e5a87ff9961ad80a94b894237 110 SUPERFAMILY SSF46785 10 97 3.01E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 80 89 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 440 1.2E-139 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 Gene3D G3DSA:3.40.630.10 5 194 4.0E-27 T 29-03-2018 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 Pfam PF01546 Peptidase family M20/M25/M40 83 442 1.5E-29 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 SUPERFAMILY SSF53187 364 447 7.43E-66 T 29-03-2018 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 SUPERFAMILY SSF53187 1 187 7.43E-66 T 29-03-2018 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 Gene3D G3DSA:3.30.70.360 260 353 1.5E-20 T 29-03-2018 CWR56_RS09395 cf3f01c02d4bfe222a14a7ed7f1a060f 448 SUPERFAMILY SSF55031 187 360 1.32E-37 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 SUPERFAMILY SSF47384 172 249 5.69E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 SUPERFAMILY SSF55874 254 407 1.44E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 Gene3D G3DSA:1.10.287.130 177 247 2.6E-12 T 29-03-2018 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 Gene3D G3DSA:3.30.565.10 254 410 2.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 186 250 1.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 297 407 2.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 SMART SM00387 296 409 6.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 2.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 2.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 362 2.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 406 2.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08075 f903af5fb9d1234a3386f3e45977b8c0 410 SMART SM00388 184 251 2.8E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 614 3.0E-198 T 29-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 Pfam PF02378 Phosphotransferase system, EIIC 113 390 2.6E-34 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 483 601 7.3E-36 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 SUPERFAMILY SSF51261 471 612 4.19E-45 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 Gene3D G3DSA:3.30.1360.60 4 80 2.9E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 479 604 6.3E-44 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 Gene3D G3DSA:2.70.70.10 466 622 9.2E-48 T 29-03-2018 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 543 555 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 Pfam PF00367 phosphotransferase system, EIIB 9 39 6.0E-15 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15565 9f1ad153a8c160cd511ec41a7ba91ebd 623 SUPERFAMILY SSF55604 7 81 3.27E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS12130 763ef614659b64cfc9b19b22c6ca7ad2 143 Pfam PF00692 dUTPase 12 142 7.7E-36 T 29-03-2018 IPR029054 dUTPase-like CWR56_RS12130 763ef614659b64cfc9b19b22c6ca7ad2 143 TIGRFAM TIGR00576 dut: dUTP diphosphatase 4 142 1.8E-59 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CWR56_RS12130 763ef614659b64cfc9b19b22c6ca7ad2 143 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 2 143 29.996 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CWR56_RS12130 763ef614659b64cfc9b19b22c6ca7ad2 143 Gene3D G3DSA:2.70.40.10 106 143 3.7E-15 T 29-03-2018 CWR56_RS12130 763ef614659b64cfc9b19b22c6ca7ad2 143 SUPERFAMILY SSF51283 4 142 1.96E-50 T 29-03-2018 IPR029054 dUTPase-like CWR56_RS12130 763ef614659b64cfc9b19b22c6ca7ad2 143 Gene3D G3DSA:2.70.40.10 1 105 1.5E-47 T 29-03-2018 CWR56_RS06785 cbea9b84519c6670f4f8189b3518a615 354 SUPERFAMILY SSF55797 232 353 3.14E-21 T 29-03-2018 IPR014044 CAP domain CWR56_RS06785 cbea9b84519c6670f4f8189b3518a615 354 Gene3D G3DSA:3.30.1450.10 72 142 4.0E-4 T 29-03-2018 CWR56_RS06785 cbea9b84519c6670f4f8189b3518a615 354 Gene3D G3DSA:3.40.33.10 224 354 5.3E-15 T 29-03-2018 IPR014044 CAP domain CWR56_RS06785 cbea9b84519c6670f4f8189b3518a615 354 Pfam PF14504 CAP-associated N-terminal 85 218 7.4E-35 T 29-03-2018 IPR029410 CAP-associated domain CWR56_RS06785 cbea9b84519c6670f4f8189b3518a615 354 Pfam PF00188 Cysteine-rich secretory protein family 238 352 6.3E-16 T 29-03-2018 IPR014044 CAP domain CWR56_RS04545 f9a10b910a9b5e57d28719540ed2435b 242 Gene3D G3DSA:1.10.3720.10 38 237 2.7E-21 T 29-03-2018 CWR56_RS04545 f9a10b910a9b5e57d28719540ed2435b 242 SUPERFAMILY SSF161098 7 232 9.42E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04545 f9a10b910a9b5e57d28719540ed2435b 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 236 1.0E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 SUPERFAMILY SSF56601 10 296 1.16E-62 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 34 275 4.2E-59 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 Gene3D G3DSA:3.40.710.10 31 305 2.1E-39 T 29-03-2018 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 296 382 5.7E-7 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 Gene3D G3DSA:2.60.410.10 306 384 1.1E-12 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 SUPERFAMILY SSF69189 288 380 8.04E-8 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 SMART SM00936 296 384 6.2E-13 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 7.7E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 63 74 7.7E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS10315 291d6955c4791d6fec6dc776fa285c22 397 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 7.7E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS16850 eaa7082acb231c108d54e7db632aea67 318 SMART SM00267 159 318 2.2E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS16850 eaa7082acb231c108d54e7db632aea67 318 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 169 313 4.5E-26 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS16850 eaa7082acb231c108d54e7db632aea67 318 SUPERFAMILY SSF55073 175 317 1.26E-33 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS16850 eaa7082acb231c108d54e7db632aea67 318 Gene3D G3DSA:3.30.70.270 163 318 3.2E-32 T 29-03-2018 CWR56_RS16850 eaa7082acb231c108d54e7db632aea67 318 Pfam PF13474 SnoaL-like domain 26 138 8.0E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWR56_RS16850 eaa7082acb231c108d54e7db632aea67 318 Pfam PF00990 Diguanylate cyclase, GGDEF domain 172 312 1.0E-27 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06005 5b8bb1ea3e1d56508a3b37d70cb08f8e 239 Gene3D G3DSA:1.10.10.580 168 235 8.3E-11 T 29-03-2018 CWR56_RS06005 5b8bb1ea3e1d56508a3b37d70cb08f8e 239 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 237 19.956 T 29-03-2018 IPR003768 Segregation and condensation protein A CWR56_RS06005 5b8bb1ea3e1d56508a3b37d70cb08f8e 239 Pfam PF02616 Segregation and condensation protein ScpA 20 233 1.3E-23 T 29-03-2018 IPR003768 Segregation and condensation protein A CWR56_RS10340 68428337de49fa3cae87999084086a80 355 TIGRFAM TIGR03073 release_rtcB: release factor H-coupled RctB family protein 5 349 1.2E-118 T 29-03-2018 IPR017510 Release factor H-coupled RctB family protein CWR56_RS10340 68428337de49fa3cae87999084086a80 355 Pfam PF01139 tRNA-splicing ligase RtcB 21 91 1.7E-9 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CWR56_RS10340 68428337de49fa3cae87999084086a80 355 Pfam PF01139 tRNA-splicing ligase RtcB 112 355 2.0E-56 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CWR56_RS10340 68428337de49fa3cae87999084086a80 355 SUPERFAMILY SSF103365 9 355 6.93E-86 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CWR56_RS15015 0589c280516a3481c2c658cd71ed4e7a 111 Gene3D G3DSA:1.10.10.10 17 108 2.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15015 0589c280516a3481c2c658cd71ed4e7a 111 SUPERFAMILY SSF46785 6 106 2.48E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15015 0589c280516a3481c2c658cd71ed4e7a 111 Pfam PF01638 HxlR-like helix-turn-helix 19 107 6.2E-20 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 61 85 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 168 188 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 355 372 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 115 125 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 392 405 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 318 340 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 PRINTS PR00906 SecA protein signature 99 113 9.0E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SMART SM00490 442 536 0.0069 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 780 19.186 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SUPERFAMILY SSF81767 225 347 5.62E-42 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 768 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SMART SM00957 4 381 1.7E-263 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SUPERFAMILY SSF52540 347 394 8.22E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SUPERFAMILY SSF52540 8 226 8.22E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Gene3D G3DSA:3.40.50.300 396 590 5.8E-52 T 29-03-2018 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SMART SM00958 226 337 1.8E-57 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Pfam PF07516 SecA Wing and Scaffold domain 575 779 1.5E-53 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SUPERFAMILY SSF52540 396 573 3.83E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 SUPERFAMILY SSF81886 577 779 6.28E-58 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Pfam PF01043 SecA preprotein cross-linking domain 231 337 3.0E-37 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Gene3D G3DSA:3.40.50.300 7 268 1.6E-53 T 29-03-2018 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Gene3D G3DSA:3.40.50.300 289 395 1.8E-9 T 29-03-2018 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Gene3D G3DSA:1.10.3060.10 678 780 1.9E-21 T 29-03-2018 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Gene3D G3DSA:1.10.3060.10 591 660 1.5E-25 T 29-03-2018 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 ProSitePatterns PS01312 SecA family signature. 479 494 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CWR56_RS14165 151e609c09b9280b3ed1d29c39df8dc5 780 Pfam PF07517 SecA DEAD-like domain 7 381 6.0E-128 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR56_RS13140 8096b33b8f6ccb5ca11ec129de7725b2 259 Gene3D G3DSA:3.20.20.370 17 258 3.7E-65 T 29-03-2018 CWR56_RS13140 8096b33b8f6ccb5ca11ec129de7725b2 259 Pfam PF01522 Polysaccharide deacetylase 53 173 1.1E-35 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS13140 8096b33b8f6ccb5ca11ec129de7725b2 259 SUPERFAMILY SSF88713 42 250 2.43E-65 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS12555 aecb1437c6c061134b3477be6c955347 392 Gene3D G3DSA:3.40.640.10 100 274 6.0E-28 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS12555 aecb1437c6c061134b3477be6c955347 392 Gene3D G3DSA:3.90.1150.10 275 392 7.0E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS12555 aecb1437c6c061134b3477be6c955347 392 Pfam PF00155 Aminotransferase class I and II 60 384 8.3E-31 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS12555 aecb1437c6c061134b3477be6c955347 392 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 4.2E-103 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR56_RS12555 aecb1437c6c061134b3477be6c955347 392 SUPERFAMILY SSF53383 30 390 2.76E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12555 aecb1437c6c061134b3477be6c955347 392 Gene3D G3DSA:3.90.1150.10 1 99 1.3E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 Gene3D G3DSA:3.20.20.140 65 460 4.1E-70 T 29-03-2018 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 SUPERFAMILY SSF51338 1 56 1.04E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 SUPERFAMILY SSF51338 479 523 1.04E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 SUPERFAMILY SSF51556 56 296 1.02E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 SUPERFAMILY SSF51556 339 479 1.02E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 Pfam PF07969 Amidohydrolase family 44 258 2.4E-10 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 Pfam PF07969 Amidohydrolase family 432 522 5.4E-11 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 Gene3D G3DSA:2.30.40.10 1 64 2.2E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS03240 273b2b91af0da4f63dad56eb8d1ab3cb 546 Gene3D G3DSA:2.30.40.10 461 532 1.5E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 Pfam PF13416 Bacterial extracellular solute-binding protein 47 315 5.0E-41 T 29-03-2018 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 SUPERFAMILY SSF53850 32 348 1.66E-94 T 29-03-2018 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 296 322 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 166 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 170 189 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 53 74 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 207 226 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 80 94 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 96 109 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 251 270 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 37 53 8.2E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 Gene3D G3DSA:3.40.190.10 24 203 1.1E-32 T 29-03-2018 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 PIRSF PIRSF019574 1 350 2.0E-123 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR56_RS04685 173938c82ebf7b9190d5bcb3f371d13c 350 Gene3D G3DSA:3.40.190.10 204 318 6.6E-19 T 29-03-2018 CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 2.7E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 Pfam PF00072 Response regulator receiver domain 5 112 4.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 SMART SM00448 2 112 4.6E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 SUPERFAMILY SSF52172 1 170 3.02E-33 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 Gene3D G3DSA:3.40.50.2300 1 118 1.8E-28 T 29-03-2018 CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 Gene3D G3DSA:1.10.10.10 119 225 2.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16430 e38a551c0e7ce338029b12d3f6628f42 225 SMART SM00862 147 223 7.5E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14270 5d1776ad1f14410b9e34bb5cbfb007ab 453 PIRSF PIRSF002746 1 446 4.8E-122 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR56_RS14270 5d1776ad1f14410b9e34bb5cbfb007ab 453 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 444 1.3E-102 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR56_RS14270 5d1776ad1f14410b9e34bb5cbfb007ab 453 Pfam PF02447 GntP family permease 1 444 6.3E-115 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 PIRSF PIRSF002158 3 276 1.1E-96 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 SUPERFAMILY SSF50104 126 273 4.21E-61 T 29-03-2018 IPR008991 Translation protein SH3-like domain CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 Gene3D G3DSA:2.40.50.140 1 114 7.0E-48 T 29-03-2018 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 Gene3D G3DSA:2.30.30.30 118 195 4.6E-34 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 4.2E-133 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 Gene3D G3DSA:4.10.950.10 197 275 1.7E-34 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 SMART SM01383 42 118 2.0E-44 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 SUPERFAMILY SSF50249 2 125 3.32E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.083 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 SMART SM01382 124 253 2.8E-93 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 8.2E-33 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00100 c13b08aed56630dd43d1dbf9f4c410c9 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 1.4E-55 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR56_RS06880 adf722f43bbb9bb39576d4e7db51559e 129 SMART SM00345 17 76 4.2E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06880 adf722f43bbb9bb39576d4e7db51559e 129 SUPERFAMILY SSF46785 6 80 5.77E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06880 adf722f43bbb9bb39576d4e7db51559e 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 8.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06880 adf722f43bbb9bb39576d4e7db51559e 129 Gene3D G3DSA:1.10.10.10 1 78 2.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13430 3ecf77773e70254a0d5da40e28317879 322 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 50 62 1.4E-4 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13430 3ecf77773e70254a0d5da40e28317879 322 ProSitePatterns PS01347 MraY family signature 1. 50 62 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13430 3ecf77773e70254a0d5da40e28317879 322 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 20 321 3.3E-101 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13430 3ecf77773e70254a0d5da40e28317879 322 ProSitePatterns PS01348 MraY family signature 2. 167 178 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13430 3ecf77773e70254a0d5da40e28317879 322 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 7 322 22.212 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR56_RS13430 3ecf77773e70254a0d5da40e28317879 322 Pfam PF00953 Glycosyl transferase family 4 80 247 2.6E-38 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 SUPERFAMILY SSF47741 82 153 3.53E-32 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 55 1.1E-7 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 Gene3D G3DSA:1.10.150.120 76 155 2.0E-33 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 SUPERFAMILY SSF54292 3 79 3.28E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 Pfam PF01799 [2Fe-2S] binding domain 74 147 8.7E-31 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS10020 f11b6fff376d3545374db819157e970a 156 Gene3D G3DSA:3.10.20.30 1 75 1.1E-23 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS02105 c2e69e0aeb0c3434faf698b747533a0a 886 Pfam PF02687 FtsX-like permease family 784 872 5.3E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS02105 c2e69e0aeb0c3434faf698b747533a0a 886 Pfam PF02687 FtsX-like permease family 317 413 2.1E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 SUPERFAMILY SSF52540 70 358 2.04E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 Gene3D G3DSA:3.40.50.300 220 370 1.4E-35 T 29-03-2018 CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 SMART SM00490 257 338 6.3E-25 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 SMART SM00487 21 221 5.1E-40 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 Gene3D G3DSA:3.40.50.300 1 219 1.4E-42 T 29-03-2018 CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 Pfam PF00270 DEAD/DEAH box helicase 26 193 1.2E-35 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS10115 ad7e437b3c07c8f79d2af689cf057923 381 Pfam PF00271 Helicase conserved C-terminal domain 230 338 3.7E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 SUPERFAMILY SSF102114 149 387 9.55E-34 T 29-03-2018 CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 PIRSF PIRSF004911 28 421 9.9E-140 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 Pfam PF12544 Lysine-2,3-aminomutase 351 410 9.2E-19 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 Gene3D G3DSA:3.20.20.70 148 363 4.8E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 TIGRFAM TIGR04368 Glu_2_3_NH3_mut: glutamate 2,3-aminomutase 4 405 6.0E-216 T 29-03-2018 IPR030801 Glutamate 2,3-aminomutase GO:0016869 CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 Pfam PF04055 Radical SAM superfamily 158 310 5.9E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS11170 8250c1174b64a37968afb5ac3f777c2a 422 TIGRFAM TIGR00238 TIGR00238: KamA family protein 46 370 8.4E-104 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CWR56_RS06510 5efbcc5ffb19d8feb507589a4f0c17eb 296 SUPERFAMILY SSF103481 186 284 3.14E-11 T 29-03-2018 CWR56_RS06510 5efbcc5ffb19d8feb507589a4f0c17eb 296 Pfam PF00892 EamA-like transporter family 11 142 2.4E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS06510 5efbcc5ffb19d8feb507589a4f0c17eb 296 Pfam PF00892 EamA-like transporter family 152 281 1.7E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS06510 5efbcc5ffb19d8feb507589a4f0c17eb 296 SUPERFAMILY SSF103481 45 144 7.72E-10 T 29-03-2018 CWR56_RS10955 ddc2abfe08d7fcf19fd2ecc9f8fb6776 281 SUPERFAMILY SSF52540 2 222 6.48E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10955 ddc2abfe08d7fcf19fd2ecc9f8fb6776 281 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS10955 ddc2abfe08d7fcf19fd2ecc9f8fb6776 281 Pfam PF00005 ABC transporter 18 157 3.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10955 ddc2abfe08d7fcf19fd2ecc9f8fb6776 281 Gene3D G3DSA:3.40.50.300 1 255 7.1E-56 T 29-03-2018 CWR56_RS10955 ddc2abfe08d7fcf19fd2ecc9f8fb6776 281 SMART SM00382 26 204 5.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 SUPERFAMILY SSF50494 291 474 1.63E-39 T 29-03-2018 IPR009003 Peptidase S1, PA clan CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 Pfam PF14266 Putative component of 'biosynthetic module' 39 226 1.3E-24 T 29-03-2018 IPR025647 Putative component of 'biosynthetic module' CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 Gene3D G3DSA:2.40.10.10 283 382 8.4E-21 T 29-03-2018 CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 PRINTS PR00834 HtrA/DegQ protease family signature 439 456 5.7E-13 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 PRINTS PR00834 HtrA/DegQ protease family signature 387 411 5.7E-13 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 PRINTS PR00834 HtrA/DegQ protease family signature 325 337 5.7E-13 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 Pfam PF13365 Trypsin-like peptidase domain 316 446 2.4E-24 T 29-03-2018 CWR56_RS07765 6db862fb9185228776ad412c04f8248a 478 Gene3D G3DSA:2.40.10.10 383 472 1.5E-21 T 29-03-2018 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 SUPERFAMILY SSF51261 476 613 2.62E-44 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 Gene3D G3DSA:3.30.1360.60 3 77 2.8E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 Pfam PF02378 Phosphotransferase system, EIIC 110 399 1.2E-33 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 Gene3D G3DSA:2.70.70.10 472 623 1.7E-47 T 29-03-2018 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 SUPERFAMILY SSF55604 8 79 3.53E-17 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 Pfam PF00367 phosphotransferase system, EIIB 10 41 4.1E-12 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 484 600 3.0E-38 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS02155 f6694a7fea35d6303906b499933f8c75 624 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 482 604 1.4E-42 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS02575 7920b1f79a77ba1cc98990b0f9dc00fa 187 SUPERFAMILY SSF46785 1 125 8.82E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02575 7920b1f79a77ba1cc98990b0f9dc00fa 187 SMART SM00418 11 96 0.0048 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS02575 7920b1f79a77ba1cc98990b0f9dc00fa 187 Pfam PF12840 Helix-turn-helix domain 13 67 5.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02575 7920b1f79a77ba1cc98990b0f9dc00fa 187 Gene3D G3DSA:1.10.10.10 5 169 2.4E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Gene3D G3DSA:3.40.50.300 1 140 5.4E-30 T 29-03-2018 CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Gene3D G3DSA:3.40.50.300 146 280 1.9E-35 T 29-03-2018 CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 270 2.5E-87 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 SUPERFAMILY SSF52540 3 653 1.27E-176 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Pfam PF12073 Protein of unknown function (DUF3553) 714 752 8.8E-6 T 29-03-2018 IPR021938 Protein of unknown function DUF3553 CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Pfam PF13361 UvrD-like helicase C-terminal domain 275 627 1.5E-78 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Gene3D G3DSA:3.40.50.300 281 382 1.3E-28 T 29-03-2018 CWR56_RS01715 38a797548f0063695b49eacbbc13e339 754 Gene3D G3DSA:1.10.486.10 383 562 3.2E-44 T 29-03-2018 CWR56_RS05885 a4ccfd45e8fecd4405b8ae3b9025bfc4 114 SUPERFAMILY SSF52980 9 102 7.51E-25 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWR56_RS05885 a4ccfd45e8fecd4405b8ae3b9025bfc4 114 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 4 113 5.2E-23 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CWR56_RS05885 a4ccfd45e8fecd4405b8ae3b9025bfc4 114 Pfam PF02021 Uncharacterised protein family UPF0102 10 100 5.8E-27 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CWR56_RS05885 a4ccfd45e8fecd4405b8ae3b9025bfc4 114 Gene3D G3DSA:3.40.1350.10 9 114 1.3E-31 T 29-03-2018 CWR56_RS05885 a4ccfd45e8fecd4405b8ae3b9025bfc4 114 Hamap MF_00048 UPF0102 protein YraN [yraN]. 3 113 21.902 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 6.1E-108 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 Pfam PF00318 Ribosomal protein S2 9 224 6.8E-100 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.221 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 SUPERFAMILY SSF52313 6 234 1.57E-97 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.1E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.1E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.1E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.1E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.1E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.1E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS10310 d4069f97242f89d9200ae898bd4b775e 237 Gene3D G3DSA:3.40.50.10490 5 237 1.1E-100 T 29-03-2018 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 360 373 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 Gene3D G3DSA:1.10.10.10 589 666 8.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 542 551 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 Gene3D G3DSA:3.40.50.300 331 509 2.8E-25 T 29-03-2018 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 423 438 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 Gene3D G3DSA:3.30.450.20 198 318 3.3E-6 T 29-03-2018 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 SMART SM00091 212 279 0.0077 T 29-03-2018 IPR000014 PAS domain CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 Gene3D G3DSA:1.10.8.60 510 582 2.0E-12 T 29-03-2018 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 Pfam PF00158 Sigma-54 interaction domain 338 503 4.4E-69 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 SUPERFAMILY SSF52540 340 562 5.05E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 SUPERFAMILY SSF55785 204 264 8.38E-6 T 29-03-2018 IPR000014 PAS domain CWR56_RS05405 56839ddadbe843627f45081c81eec255 666 SMART SM00382 356 501 1.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01375 e676c3d31996c358d1b23ec7dd764edf 257 SUPERFAMILY SSF117143 93 195 1.11E-23 T 29-03-2018 CWR56_RS01375 e676c3d31996c358d1b23ec7dd764edf 257 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 250 1.2E-15 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CWR56_RS01375 e676c3d31996c358d1b23ec7dd764edf 257 Pfam PF00460 Flagella basal body rod protein 5 35 1.4E-11 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CWR56_RS01375 e676c3d31996c358d1b23ec7dd764edf 257 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 142 1.4E-36 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CWR56_RS10930 995e2a8432e2912bb5dcd225ab4b5fd9 238 Pfam PF13649 Methyltransferase domain 42 122 1.8E-8 T 29-03-2018 CWR56_RS10930 995e2a8432e2912bb5dcd225ab4b5fd9 238 SUPERFAMILY SSF53335 6 197 8.52E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS10930 995e2a8432e2912bb5dcd225ab4b5fd9 238 Gene3D G3DSA:3.40.50.150 25 223 9.6E-17 T 29-03-2018 CWR56_RS18255 fbc58fe5a6eaeab599d788b3ce57d875 700 Pfam PF00563 EAL domain 451 683 1.1E-55 T 29-03-2018 IPR001633 EAL domain CWR56_RS18255 fbc58fe5a6eaeab599d788b3ce57d875 700 Pfam PF02378 Phosphotransferase system, EIIC 20 339 2.0E-24 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS18255 fbc58fe5a6eaeab599d788b3ce57d875 700 SMART SM00052 448 689 1.7E-66 T 29-03-2018 IPR001633 EAL domain CWR56_RS18255 fbc58fe5a6eaeab599d788b3ce57d875 700 SUPERFAMILY SSF141868 450 695 4.58E-70 T 29-03-2018 IPR001633 EAL domain CWR56_RS18255 fbc58fe5a6eaeab599d788b3ce57d875 700 Gene3D G3DSA:3.20.20.450 445 700 5.7E-72 T 29-03-2018 IPR001633 EAL domain CWR56_RS09515 ea0836ec58135a636a41258b26fa8b07 60 SUPERFAMILY SSF56349 8 51 2.65E-9 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS09515 ea0836ec58135a636a41258b26fa8b07 60 Gene3D G3DSA:1.10.443.10 6 55 7.3E-9 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS09660 2f8a4ba5b5f628a75d9d992b6fd0b1cb 134 Pfam PF05732 Firmicute plasmid replication protein (RepL) 25 131 1.9E-11 T 29-03-2018 IPR008813 Plasmid replication protein, RepL GO:0006260|GO:0006276 CWR56_RS17435 c290c5d77b485d757a7f764eed23169c 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.4E-10 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR56_RS17435 c290c5d77b485d757a7f764eed23169c 92 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.4E-10 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR56_RS17435 c290c5d77b485d757a7f764eed23169c 92 SUPERFAMILY SSF47729 1 91 1.47E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CWR56_RS17435 c290c5d77b485d757a7f764eed23169c 92 SMART SM00411 1 91 1.4E-38 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR56_RS17435 c290c5d77b485d757a7f764eed23169c 92 Pfam PF00216 Bacterial DNA-binding protein 1 91 7.4E-31 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR56_RS17435 c290c5d77b485d757a7f764eed23169c 92 Gene3D G3DSA:4.10.520.10 1 92 1.1E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CWR56_RS05265 2757484b7c71ec01495522d394ff9eda 233 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 5 222 8.5E-67 T 29-03-2018 IPR018768 Domain of unknown function DUF2344 CWR56_RS05265 2757484b7c71ec01495522d394ff9eda 233 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 5 193 2.2E-58 T 29-03-2018 IPR018768 Domain of unknown function DUF2344 CWR56_RS03720 1e6900e8dd28108f8b7374d723128e73 188 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 95 187 1.5E-45 T 29-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS03720 1e6900e8dd28108f8b7374d723128e73 188 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 3 40 1.7E-6 T 29-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS04275 4cb85b488f1e3e35cb92c42e3a7c8304 227 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 9 215 1.5E-77 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CWR56_RS04275 4cb85b488f1e3e35cb92c42e3a7c8304 227 SUPERFAMILY SSF161098 5 214 7.19E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04275 4cb85b488f1e3e35cb92c42e3a7c8304 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 225 2.4E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04275 4cb85b488f1e3e35cb92c42e3a7c8304 227 Gene3D G3DSA:1.10.3720.10 3 219 4.3E-42 T 29-03-2018 CWR56_RS03460 69e80e87ec966f554cc720963f635b18 303 Pfam PF01515 Phosphate acetyl/butaryl transferase 78 294 9.2E-40 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS03460 69e80e87ec966f554cc720963f635b18 303 Gene3D G3DSA:3.40.50.10750 115 272 8.0E-37 T 29-03-2018 CWR56_RS03460 69e80e87ec966f554cc720963f635b18 303 PIRSF PIRSF000428 1 303 3.4E-80 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS03460 69e80e87ec966f554cc720963f635b18 303 SUPERFAMILY SSF53659 5 299 1.01E-57 T 29-03-2018 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 Gene3D G3DSA:3.30.565.10 251 408 5.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 Gene3D G3DSA:1.10.287.130 180 250 4.5E-10 T 29-03-2018 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 408 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 Pfam PF00512 His Kinase A (phospho-acceptor) domain 194 255 3.5E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 410 7.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 SMART SM00388 190 256 1.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 SMART SM00387 301 411 4.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 SUPERFAMILY SSF55874 246 407 5.89E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS00785 b0185b09a4a476952aebfb0357d643a4 413 SUPERFAMILY SSF47384 174 256 1.02E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS15420 7224df7c34bf4a9c7703001890359fbc 241 SUPERFAMILY SSF46689 1 76 9.14E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS15420 7224df7c34bf4a9c7703001890359fbc 241 Gene3D G3DSA:3.40.50.10490 101 238 8.6E-21 T 29-03-2018 CWR56_RS15420 7224df7c34bf4a9c7703001890359fbc 241 Pfam PF01380 SIS domain 108 210 2.0E-12 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS15420 7224df7c34bf4a9c7703001890359fbc 241 SUPERFAMILY SSF53697 89 238 3.67E-24 T 29-03-2018 CWR56_RS15420 7224df7c34bf4a9c7703001890359fbc 241 Gene3D G3DSA:1.10.10.10 1 100 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15420 7224df7c34bf4a9c7703001890359fbc 241 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 76 8.1E-14 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS17075 dc8535cb108e219f0a34c3cd3e1ef0c4 191 SUPERFAMILY SSF53335 6 157 3.01E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS17075 dc8535cb108e219f0a34c3cd3e1ef0c4 191 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 12 133 4.7E-36 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CWR56_RS17075 dc8535cb108e219f0a34c3cd3e1ef0c4 191 Gene3D G3DSA:3.40.50.150 1 191 2.8E-25 T 29-03-2018 CWR56_RS17075 dc8535cb108e219f0a34c3cd3e1ef0c4 191 Pfam PF13847 Methyltransferase domain 31 87 1.5E-8 T 29-03-2018 IPR025714 Methyltransferase domain CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 SUPERFAMILY SSF50022 422 496 4.19E-25 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 Pfam PF00355 Rieske [2Fe-2S] domain 417 496 3.1E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 Gene3D G3DSA:3.50.50.60 13 391 5.0E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 SUPERFAMILY SSF51905 23 294 2.49E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 Pfam PF01266 FAD dependent oxidoreductase 25 370 1.5E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 Gene3D G3DSA:2.102.10.10 396 499 6.8E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 481 493 5.1E-8 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 448 459 5.1E-8 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CWR56_RS11235 969ebfb82e89a8f9ccc31bc1656bd5da 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 469 481 5.1E-8 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 Gene3D G3DSA:3.40.1410.10 85 238 2.8E-28 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.5E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 SMART SM00345 15 74 5.2E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 SUPERFAMILY SSF46785 6 85 2.87E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 SUPERFAMILY SSF64288 64 237 7.69E-35 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 Gene3D G3DSA:1.10.10.10 1 76 1.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 Pfam PF07702 UTRA domain 98 234 7.4E-29 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 SMART SM00866 95 234 4.4E-27 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04960 ec4173407c30a448975c570f25463a54 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS12365 ce8e6d7a25377d9efa6b0f10993d11f0 116 PRINTS PR00332 Histidine triad family signature 93 103 1.1E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CWR56_RS12365 ce8e6d7a25377d9efa6b0f10993d11f0 116 PRINTS PR00332 Histidine triad family signature 4 20 1.1E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CWR56_RS12365 ce8e6d7a25377d9efa6b0f10993d11f0 116 PRINTS PR00332 Histidine triad family signature 25 43 1.1E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CWR56_RS12365 ce8e6d7a25377d9efa6b0f10993d11f0 116 Pfam PF01230 HIT domain 11 107 2.2E-26 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CWR56_RS12365 ce8e6d7a25377d9efa6b0f10993d11f0 116 SUPERFAMILY SSF54197 1 109 1.53E-38 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CWR56_RS12365 ce8e6d7a25377d9efa6b0f10993d11f0 116 Gene3D G3DSA:3.30.428.10 1 116 4.9E-34 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CWR56_RS13580 4c30769580fd995ccf84f7fe194cbbde 204 SUPERFAMILY SSF52218 16 197 3.86E-26 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS13580 4c30769580fd995ccf84f7fe194cbbde 204 Pfam PF03358 NADPH-dependent FMN reductase 15 145 5.1E-19 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS13580 4c30769580fd995ccf84f7fe194cbbde 204 Gene3D G3DSA:3.40.50.360 9 191 4.7E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS12755 67bbcd1d605aec58966dc4b626746f13 190 SMART SM00471 14 142 9.4E-8 T 29-03-2018 IPR003607 HD/PDEase domain CWR56_RS12755 67bbcd1d605aec58966dc4b626746f13 190 SUPERFAMILY SSF109604 4 178 2.05E-32 T 29-03-2018 CWR56_RS12755 67bbcd1d605aec58966dc4b626746f13 190 TIGRFAM TIGR00277 HDIG: HDIG domain 19 111 6.7E-11 T 29-03-2018 IPR006675 HDIG domain CWR56_RS12755 67bbcd1d605aec58966dc4b626746f13 190 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 11 183 1.5E-42 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CWR56_RS12755 67bbcd1d605aec58966dc4b626746f13 190 Gene3D G3DSA:1.10.3210.10 1 189 4.2E-32 T 29-03-2018 CWR56_RS12755 67bbcd1d605aec58966dc4b626746f13 190 Pfam PF01966 HD domain 18 131 9.7E-19 T 29-03-2018 IPR006674 HD domain CWR56_RS09930 56719e270c5fa0f48f53bd8b21127e4c 240 TIGRFAM TIGR03172 TIGR03172: putative selenium-dependent hydroxylase accessory protein YqeC 12 232 3.1E-44 T 29-03-2018 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 SMART SM00729 176 382 9.4E-24 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 Gene3D G3DSA:3.20.20.70 126 497 1.5E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 SUPERFAMILY SSF52242 42 149 3.37E-6 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 SUPERFAMILY SSF102114 159 379 1.12E-42 T 29-03-2018 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 Pfam PF13311 Protein of unknown function (DUF4080) 370 566 1.4E-53 T 29-03-2018 IPR025288 Domain of unknown function DUF4080 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 Pfam PF02310 B12 binding domain 9 122 2.4E-16 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 Gene3D G3DSA:3.40.50.280 1 124 1.3E-9 T 29-03-2018 CWR56_RS03435 d883e2272defb00036aa4a7663edb2c5 584 Pfam PF04055 Radical SAM superfamily 181 343 3.7E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 SUPERFAMILY SSF55136 146 305 2.62E-32 T 29-03-2018 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 Gene3D G3DSA:1.10.10.60 62 121 5.5E-12 T 29-03-2018 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 Pfam PF12833 Helix-turn-helix domain 34 113 8.1E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 Gene3D G3DSA:3.20.80.10 143 305 6.3E-28 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 SUPERFAMILY SSF46689 68 116 2.96E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 Gene3D G3DSA:1.10.10.60 2 61 1.9E-15 T 29-03-2018 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 Pfam PF06445 GyrI-like small molecule binding domain 146 303 2.9E-27 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 SUPERFAMILY SSF46689 12 62 4.3E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 65 108 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 SMART SM00871 145 304 6.9E-36 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 96 112 1.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 81 96 1.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS16040 39ea5f3dcc60b41c361e40976d9ecc5d 306 SMART SM00342 28 112 5.3E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 SUPERFAMILY SSF46785 38 158 8.99E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 Pfam PF01047 MarR family 58 107 3.7E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 SMART SM00347 43 143 3.0E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS12140 05e82db3a887c9543481f007c22d5a03 161 Gene3D G3DSA:1.10.10.10 28 159 2.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 Gene3D G3DSA:3.40.50.300 137 309 8.0E-43 T 29-03-2018 CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 7 305 4.9E-116 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 SUPERFAMILY SSF75138 6 134 9.16E-36 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 6 309 40.935 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 Pfam PF07475 HPr Serine kinase C-terminal domain 133 301 3.2E-75 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 Pfam PF02603 HPr Serine kinase N terminus 7 130 3.5E-39 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 SUPERFAMILY SSF53795 135 301 5.49E-40 T 29-03-2018 CWR56_RS16970 edf15932c576ce7f4a631530cb99ca2b 309 Gene3D G3DSA:3.40.1390.20 6 135 1.2E-40 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR56_RS02160 53349ef1d394fb2a970d812259cf08d9 599 Pfam PF05569 BlaR1 peptidase M56 9 310 3.0E-64 T 29-03-2018 IPR008756 Peptidase M56 CWR56_RS02160 53349ef1d394fb2a970d812259cf08d9 599 Gene3D G3DSA:3.30.2010.10 141 231 7.9E-4 T 29-03-2018 CWR56_RS02160 53349ef1d394fb2a970d812259cf08d9 599 Gene3D G3DSA:3.40.710.10 372 594 3.9E-31 T 29-03-2018 CWR56_RS02160 53349ef1d394fb2a970d812259cf08d9 599 Pfam PF00905 Penicillin binding protein transpeptidase domain 380 590 4.3E-39 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR56_RS02160 53349ef1d394fb2a970d812259cf08d9 599 SUPERFAMILY SSF56601 360 593 3.34E-40 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS09135 58fb7460d4bc26ee4aa9e481f387268c 363 PIRSF PIRSF019466 1 363 7.5E-146 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CWR56_RS09135 58fb7460d4bc26ee4aa9e481f387268c 363 Pfam PF04346 Ethanolamine utilisation protein, EutH 3 353 1.5E-156 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CWR56_RS08565 bc66dab3f1c6563dae9c0aa3eed50099 267 Gene3D G3DSA:3.40.50.620 5 239 3.5E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS08565 bc66dab3f1c6563dae9c0aa3eed50099 267 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 261 1.6E-82 T 29-03-2018 IPR005232 Lactate racemization operon protein LarE CWR56_RS08565 bc66dab3f1c6563dae9c0aa3eed50099 267 Pfam PF01171 PP-loop family 20 127 1.2E-8 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CWR56_RS08565 bc66dab3f1c6563dae9c0aa3eed50099 267 SUPERFAMILY SSF52402 18 225 1.37E-40 T 29-03-2018 CWR56_RS08565 bc66dab3f1c6563dae9c0aa3eed50099 267 PIRSF PIRSF006661 1 267 7.1E-100 T 29-03-2018 IPR005232 Lactate racemization operon protein LarE CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 Pfam PF00912 Transglycosylase 106 265 1.2E-53 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 Gene3D G3DSA:1.10.3810.10 98 364 1.2E-66 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 SUPERFAMILY SSF56601 381 796 1.76E-98 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 SUPERFAMILY SSF56601 333 349 1.76E-98 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 Gene3D G3DSA:3.40.710.10 366 823 1.3E-96 T 29-03-2018 CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 SUPERFAMILY SSF53955 93 265 4.5E-53 T 29-03-2018 IPR023346 Lysozyme-like domain CWR56_RS03815 b95ce4cdaec31008d05a8c038f34e28c 897 Pfam PF00905 Penicillin binding protein transpeptidase domain 450 718 4.4E-38 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 PIRSF PIRSF001491 1 390 8.3E-158 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 Hamap MF_00740 Phosphopentomutase [deoB]. 1 386 52.352 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 Pfam PF01676 Metalloenzyme superfamily 3 377 3.8E-38 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 Gene3D G3DSA:3.30.70.1250 98 205 2.1E-53 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 384 1.8E-164 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 SUPERFAMILY SSF143856 99 215 1.09E-46 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 SUPERFAMILY SSF53649 216 388 1.2E-73 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 SUPERFAMILY SSF53649 1 99 1.2E-73 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR56_RS05590 33cea0aa1d81d6561119d3f92913365b 390 Gene3D G3DSA:3.40.720.10 206 386 1.9E-15 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR56_RS18095 f41fb775ba7b43980baa7f44831aa2a6 205 TIGRFAM TIGR03608 L_ocin_972_ABC: putative bacteriocin export ABC transporter, lactococcin 972 group 4 205 7.4E-85 T 29-03-2018 IPR019895 Putative bacteriocin export ABC transporter, lactococcin 972 group CWR56_RS18095 f41fb775ba7b43980baa7f44831aa2a6 205 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS18095 f41fb775ba7b43980baa7f44831aa2a6 205 SMART SM00382 26 205 4.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18095 f41fb775ba7b43980baa7f44831aa2a6 205 Pfam PF00005 ABC transporter 18 161 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS18095 f41fb775ba7b43980baa7f44831aa2a6 205 Gene3D G3DSA:3.40.50.300 1 205 2.3E-57 T 29-03-2018 CWR56_RS18095 f41fb775ba7b43980baa7f44831aa2a6 205 SUPERFAMILY SSF52540 2 205 2.82E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12115 39ad87d6faaf361dc24b917c496a9ada 88 PIRSF PIRSF010606 1 84 2.2E-28 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB CWR56_RS12115 39ad87d6faaf361dc24b917c496a9ada 88 Pfam PF12652 CotJB protein 8 83 3.9E-30 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 Gene3D G3DSA:3.40.50.300 269 453 1.4E-23 T 29-03-2018 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 Gene3D G3DSA:1.20.1580.10 94 126 3.9E-5 T 29-03-2018 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 ProSitePatterns PS00211 ABC transporters family signature. 335 349 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 SMART SM00382 25 412 0.83 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 SMART SM00382 475 715 0.27 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 ProSitePatterns PS00211 ABC transporters family signature. 642 656 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 Gene3D G3DSA:1.10.8.280 150 257 3.3E-19 T 29-03-2018 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 Gene3D G3DSA:3.40.50.300 454 745 1.0E-51 T 29-03-2018 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 SUPERFAMILY SSF52540 460 722 8.88E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 Gene3D G3DSA:3.40.50.300 3 56 0.074 T 29-03-2018 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 Pfam PF00005 ABC transporter 466 669 1.5E-13 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 SUPERFAMILY SSF52540 13 188 4.8E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16160 b184815bde9ee0d846764546e569531c 746 SUPERFAMILY SSF52540 279 426 4.8E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00205 053e879a67ffba207e447505b7b905ed 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.907 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CWR56_RS00205 053e879a67ffba207e447505b7b905ed 72 Gene3D G3DSA:2.40.50.140 1 72 9.4E-38 T 29-03-2018 CWR56_RS00205 053e879a67ffba207e447505b7b905ed 72 SUPERFAMILY SSF50249 1 70 1.84E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS00205 053e879a67ffba207e447505b7b905ed 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 9.8E-36 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CWR56_RS00205 053e879a67ffba207e447505b7b905ed 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.8E-29 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CWR56_RS00205 053e879a67ffba207e447505b7b905ed 72 SMART SM00316 4 72 2.9E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS17410 a3c7b70eb60644e4799ed0495e9dcff9 306 Pfam PF02541 Ppx/GppA phosphatase family 32 303 1.2E-64 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CWR56_RS17410 a3c7b70eb60644e4799ed0495e9dcff9 306 SUPERFAMILY SSF53067 126 302 2.12E-44 T 29-03-2018 CWR56_RS17410 a3c7b70eb60644e4799ed0495e9dcff9 306 Gene3D G3DSA:3.30.420.150 124 305 1.5E-47 T 29-03-2018 CWR56_RS17410 a3c7b70eb60644e4799ed0495e9dcff9 306 SUPERFAMILY SSF53067 2 121 2.75E-32 T 29-03-2018 CWR56_RS17410 a3c7b70eb60644e4799ed0495e9dcff9 306 Gene3D G3DSA:3.30.420.40 1 123 4.3E-36 T 29-03-2018 CWR56_RS13255 4b47e40a4d38cb2b9904ff1af6a05c06 237 PIRSF PIRSF004848 4 237 8.7E-78 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CWR56_RS13255 4b47e40a4d38cb2b9904ff1af6a05c06 237 Pfam PF01168 Alanine racemase, N-terminal domain 10 232 1.6E-18 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS13255 4b47e40a4d38cb2b9904ff1af6a05c06 237 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 4 232 8.5E-59 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CWR56_RS13255 4b47e40a4d38cb2b9904ff1af6a05c06 237 SUPERFAMILY SSF51419 3 230 5.23E-75 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS13255 4b47e40a4d38cb2b9904ff1af6a05c06 237 Gene3D G3DSA:3.20.20.10 4 237 9.8E-60 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Pfam PF05701 Weak chloroplast movement under blue light 16 234 1.0E-9 T 29-03-2018 IPR008545 WEB family CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 SUPERFAMILY SSF57997 156 301 1.37E-5 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.20.5.10 138 159 4.7E-8 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.20.5.10 15 47 4.6E-8 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.20.5.10 97 117 1.2E-7 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.20.58.130 244 320 0.17 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.20.5.190 203 240 3.3E-7 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 SUPERFAMILY SSF57997 15 183 6.08E-7 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.10.287.540 160 179 1.3E-9 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.10.287.540 118 137 4.0E-12 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.10.287.540 72 96 1.7E-10 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.10.287.540 48 71 2.3E-11 T 29-03-2018 CWR56_RS09960 313b5ed3db1ea1321bcfd6fd28476f9b 321 Gene3D G3DSA:1.20.5.300 180 202 0.005 T 29-03-2018 CWR56_RS07510 eebb3ab6f1a24f16a4ec8bd48562217d 364 Gene3D G3DSA:1.10.10.10 19 84 2.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07510 eebb3ab6f1a24f16a4ec8bd48562217d 364 SUPERFAMILY SSF53067 94 259 1.61E-19 T 29-03-2018 CWR56_RS07510 eebb3ab6f1a24f16a4ec8bd48562217d 364 Gene3D G3DSA:3.30.420.40 85 219 3.0E-21 T 29-03-2018 CWR56_RS07510 eebb3ab6f1a24f16a4ec8bd48562217d 364 Gene3D G3DSA:3.30.420.40 220 273 1.1E-6 T 29-03-2018 CWR56_RS07510 eebb3ab6f1a24f16a4ec8bd48562217d 364 Pfam PF00480 ROK family 100 246 2.1E-19 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS07510 eebb3ab6f1a24f16a4ec8bd48562217d 364 SUPERFAMILY SSF46785 10 73 4.08E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 Pfam PF00176 SNF2 family N-terminal domain 630 881 2.2E-58 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 Gene3D G3DSA:3.40.50.300 882 1042 4.7E-39 T 29-03-2018 CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 SUPERFAMILY SSF52540 582 813 1.7E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 SUPERFAMILY SSF52540 815 1062 1.24E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 SMART SM00490 921 1004 2.3E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 Pfam PF00271 Helicase conserved C-terminal domain 892 1004 3.5E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 Gene3D G3DSA:3.40.50.300 605 863 2.1E-53 T 29-03-2018 CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 Pfam PF08455 Bacterial SNF2 helicase associated 248 604 9.0E-74 T 29-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial CWR56_RS10520 a771032a575b17462c78531617b5da23 1062 SMART SM00487 607 790 1.3E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS14820 4c6b95e10f863b36041365cf17c2dc48 233 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 225 1.3E-35 T 29-03-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type CWR56_RS14820 4c6b95e10f863b36041365cf17c2dc48 233 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 154 4.2E-10 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CWR56_RS14820 4c6b95e10f863b36041365cf17c2dc48 233 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 43 9.4E-11 T 29-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal CWR56_RS16950 a6b81fac0cd083a10de2e6bcdf8de45f 165 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 116 134 - T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16950 a6b81fac0cd083a10de2e6bcdf8de45f 165 Gene3D G3DSA:3.40.30.10 77 161 3.0E-16 T 29-03-2018 CWR56_RS16950 a6b81fac0cd083a10de2e6bcdf8de45f 165 SUPERFAMILY SSF52833 9 160 1.02E-51 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS16950 a6b81fac0cd083a10de2e6bcdf8de45f 165 PIRSF PIRSF000216 2 164 6.9E-57 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16950 a6b81fac0cd083a10de2e6bcdf8de45f 165 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 18 158 6.4E-52 T 29-03-2018 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 Pfam PF01368 DHH family 4 373 1.8E-28 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 Gene3D G3DSA:3.90.1640.10 1 415 1.1E-68 T 29-03-2018 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SMART SM00116 247 295 1.2E-4 T 29-03-2018 IPR000644 CBS domain CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SMART SM00116 74 122 0.062 T 29-03-2018 IPR000644 CBS domain CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 Pfam PF00571 CBS domain 245 291 2.3E-9 T 29-03-2018 IPR000644 CBS domain CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 Pfam PF00571 CBS domain 67 122 1.2E-8 T 29-03-2018 IPR000644 CBS domain CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SMART SM01131 408 528 5.1E-45 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SUPERFAMILY SSF64182 296 526 4.29E-69 T 29-03-2018 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SUPERFAMILY SSF64182 3 68 4.29E-69 T 29-03-2018 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SUPERFAMILY SSF54631 216 292 1.21E-21 T 29-03-2018 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SUPERFAMILY SSF54631 65 138 1.21E-21 T 29-03-2018 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 Pfam PF02833 DHHA2 domain 410 527 1.0E-16 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 SUPERFAMILY SSF75138 131 237 1.31E-17 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR56_RS01740 a16bfd46a8d6f99ac055c0fb4b24a9c8 532 Pfam PF07085 DRTGG domain 135 236 1.2E-19 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS00980 592cfd22ca3f2789514517ffa4f60c75 139 Pfam PF01969 Protein of unknown function DUF111 1 121 1.8E-36 T 29-03-2018 IPR035108 LarC/UPF0272 CWR56_RS00980 592cfd22ca3f2789514517ffa4f60c75 139 Gene3D G3DSA:3.30.70.1380 1 69 4.3E-22 T 29-03-2018 CWR56_RS00980 592cfd22ca3f2789514517ffa4f60c75 139 Gene3D G3DSA:3.10.20.300 71 137 1.8E-15 T 29-03-2018 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 PRINTS PR00050 Cold shock protein signature 4 19 4.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 PRINTS PR00050 Cold shock protein signature 24 33 4.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 PRINTS PR00050 Cold shock protein signature 39 57 4.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 1.0E-28 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 SUPERFAMILY SSF50249 1 65 8.08E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 Gene3D G3DSA:2.40.50.140 1 66 6.5E-27 T 29-03-2018 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 SMART SM00357 3 66 2.2E-28 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 PIRSF PIRSF002599 1 66 3.9E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWR56_RS09510 e9fd77d1175598378be40b5d32f307c1 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CWR56_RS02045 9eaa1d7a6e728523fdfd62c7102a0523 470 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 365 9.2E-55 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS02045 9eaa1d7a6e728523fdfd62c7102a0523 470 Gene3D G3DSA:3.40.50.1100 175 368 8.4E-24 T 29-03-2018 CWR56_RS02045 9eaa1d7a6e728523fdfd62c7102a0523 470 SUPERFAMILY SSF53686 51 366 3.93E-56 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS02045 9eaa1d7a6e728523fdfd62c7102a0523 470 Gene3D G3DSA:3.40.50.1100 77 174 1.4E-21 T 29-03-2018 CWR56_RS01295 507de623b6a5b5e5d30f3cd462cc1c6e 202 Pfam PF03963 Flagellar hook capping protein - N-terminal region 40 105 8.0E-20 T 29-03-2018 IPR005648 Flagellar hook capping protein CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 130 1.8E-33 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 Gene3D G3DSA:3.40.50.2300 161 259 6.0E-34 T 29-03-2018 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 163 244 2.8E-30 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 145 8.4E-36 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 165 243 2.2E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 277 616 5.9E-118 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 Gene3D G3DSA:3.40.930.10 2 147 1.8E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 SUPERFAMILY SSF55804 1 145 3.27E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15660 6d85444c82d0ab88ce1c7c0dd9e07544 631 SUPERFAMILY SSF52794 162 244 7.5E-31 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS07305 40656f1f773409843585093ad6809c11 346 Gene3D G3DSA:1.10.10.10 283 346 1.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07305 40656f1f773409843585093ad6809c11 346 Pfam PF02661 Fic/DOC family 107 212 2.9E-12 T 29-03-2018 IPR003812 Fido domain CWR56_RS07305 40656f1f773409843585093ad6809c11 346 SUPERFAMILY SSF140931 84 277 5.62E-25 T 29-03-2018 IPR003812 Fido domain CWR56_RS07305 40656f1f773409843585093ad6809c11 346 Gene3D G3DSA:1.10.3290.10 19 282 2.1E-37 T 29-03-2018 IPR003812 Fido domain CWR56_RS17010 c77615f7e2a6868ec75cb6d17725930e 356 SMART SM00382 29 212 4.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17010 c77615f7e2a6868ec75cb6d17725930e 356 SUPERFAMILY SSF52540 4 245 1.54E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17010 c77615f7e2a6868ec75cb6d17725930e 356 Gene3D G3DSA:3.40.50.300 1 237 4.6E-80 T 29-03-2018 CWR56_RS17010 c77615f7e2a6868ec75cb6d17725930e 356 SUPERFAMILY SSF50331 237 334 4.25E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWR56_RS17010 c77615f7e2a6868ec75cb6d17725930e 356 Pfam PF00005 ABC transporter 21 162 1.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS17010 c77615f7e2a6868ec75cb6d17725930e 356 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 Gene3D G3DSA:3.30.1330.30 3 106 1.6E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 Pfam PF00588 SpoU rRNA Methylase family 119 258 5.2E-34 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 SUPERFAMILY SSF75217 97 261 3.01E-39 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 SMART SM00967 32 108 1.6E-7 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 Gene3D G3DSA:3.40.1280.10 109 264 6.6E-38 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 32 103 3.0E-10 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR56_RS03355 d1cd224cfbb2a6864c3035ac6b825620 265 SUPERFAMILY SSF55315 5 104 1.29E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CWR56_RS09585 5c1fb6276d93edca8b9b1db53e9a0c5a 142 SUPERFAMILY SSF52218 3 142 1.8E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS09585 5c1fb6276d93edca8b9b1db53e9a0c5a 142 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CWR56_RS09585 5c1fb6276d93edca8b9b1db53e9a0c5a 142 TIGRFAM TIGR01753 flav_short: flavodoxin 4 141 5.2E-51 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CWR56_RS09585 5c1fb6276d93edca8b9b1db53e9a0c5a 142 Gene3D G3DSA:3.40.50.360 1 141 7.9E-22 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS09585 5c1fb6276d93edca8b9b1db53e9a0c5a 142 Pfam PF00258 Flavodoxin 6 135 2.5E-17 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CWR56_RS00095 b2eb97fe8f755dafe2037e28e7b2de90 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 20.404 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00095 b2eb97fe8f755dafe2037e28e7b2de90 96 Gene3D G3DSA:3.30.70.330 2 96 6.9E-34 T 29-03-2018 CWR56_RS00095 b2eb97fe8f755dafe2037e28e7b2de90 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00095 b2eb97fe8f755dafe2037e28e7b2de90 96 SUPERFAMILY SSF54189 3 94 3.24E-31 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00095 b2eb97fe8f755dafe2037e28e7b2de90 96 Pfam PF00276 Ribosomal protein L23 6 88 1.2E-33 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CWR56_RS03570 1f6cc064d86b1c4511684030569d4c3f 259 Gene3D G3DSA:3.20.20.140 2 259 9.6E-37 T 29-03-2018 CWR56_RS03570 1f6cc064d86b1c4511684030569d4c3f 259 Pfam PF02811 PHP domain 3 175 5.0E-13 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS03570 1f6cc064d86b1c4511684030569d4c3f 259 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 3 254 1.0E-62 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CWR56_RS03570 1f6cc064d86b1c4511684030569d4c3f 259 SUPERFAMILY SSF89550 2 257 3.01E-37 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 352 3.5E-138 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 356 49.647 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 SUPERFAMILY SSF53659 1 355 1.06E-121 T 29-03-2018 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 Gene3D G3DSA:3.40.718.10 1 356 5.3E-128 T 29-03-2018 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 351 1.6E-154 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 SMART SM01329 4 352 1.8E-195 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR56_RS04500 07d07ace2320796120d484698eff70ca 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 SUPERFAMILY SSF47413 3 69 5.35E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 Gene3D G3DSA:2.60.120.10 97 194 3.6E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 Gene3D G3DSA:1.10.260.40 1 96 4.3E-15 T 29-03-2018 CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 SMART SM00530 8 63 6.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 Pfam PF07883 Cupin domain 110 179 7.1E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 SUPERFAMILY SSF51182 69 179 3.06E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS07040 2ce49deb697412fd8e382a215ececea7 194 Pfam PF01381 Helix-turn-helix 9 63 2.1E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11995 2ac58e4dcd1e6b44c7255d08d67ece9e 1014 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 978 1010 1.1E-4 T 29-03-2018 CWR56_RS11995 2ac58e4dcd1e6b44c7255d08d67ece9e 1014 Gene3D G3DSA:2.60.40.810 305 433 1.5E-8 T 29-03-2018 CWR56_RS11995 2ac58e4dcd1e6b44c7255d08d67ece9e 1014 Gene3D G3DSA:2.60.40.810 440 564 1.2E-15 T 29-03-2018 CWR56_RS11995 2ac58e4dcd1e6b44c7255d08d67ece9e 1014 Gene3D G3DSA:2.60.40.810 565 725 2.8E-13 T 29-03-2018 CWR56_RS11995 2ac58e4dcd1e6b44c7255d08d67ece9e 1014 Gene3D G3DSA:2.60.40.10 203 304 4.3E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 249 1.7E-60 T 29-03-2018 CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 SUPERFAMILY SSF51735 5 249 4.11E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 Gene3D G3DSA:3.40.50.720 43 259 8.3E-56 T 29-03-2018 CWR56_RS00045 336ee3ec9840be7b004594c6484f6ad1 262 Gene3D G3DSA:3.40.50.720 1 42 1.3E-9 T 29-03-2018 CWR56_RS16090 bf3c743260a55c52c8ce66971290a7dd 216 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 22 201 5.4E-32 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWR56_RS16090 bf3c743260a55c52c8ce66971290a7dd 216 Pfam PF02096 60Kd inner membrane protein 22 202 5.4E-31 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 Pfam PF00406 Adenylate kinase 5 190 2.1E-58 T 29-03-2018 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 5.6E-20 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.219 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 6.7E-82 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 PRINTS PR00094 Adenylate kinase signature 32 46 7.9E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 PRINTS PR00094 Adenylate kinase signature 81 97 7.9E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 PRINTS PR00094 Adenylate kinase signature 177 191 7.9E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 PRINTS PR00094 Adenylate kinase signature 160 175 7.9E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 PRINTS PR00094 Adenylate kinase signature 4 17 7.9E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 Gene3D G3DSA:3.40.50.300 1 216 1.6E-68 T 29-03-2018 CWR56_RS00190 e65363f46c765b590ec87d9da8384ae3 216 SUPERFAMILY SSF52540 1 213 3.29E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 Gene3D G3DSA:3.20.20.70 1 218 1.4E-90 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 201 3.7E-86 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 SUPERFAMILY SSF51366 1 215 1.14E-79 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 PIRSF PIRSF001461 1 222 5.0E-98 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 134 156 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS13020 66ea6d274fcb96cbfc34f64366f762bf 223 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 1.7E-92 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS12930 7be8fd0370a0c7aa4704f3b907cc17da 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR56_RS12930 7be8fd0370a0c7aa4704f3b907cc17da 184 Pfam PF03602 Conserved hypothetical protein 95 1 181 1.5E-60 T 29-03-2018 CWR56_RS12930 7be8fd0370a0c7aa4704f3b907cc17da 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 182 4.5E-58 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CWR56_RS12930 7be8fd0370a0c7aa4704f3b907cc17da 184 PIRSF PIRSF004553 1 184 8.6E-58 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CWR56_RS12930 7be8fd0370a0c7aa4704f3b907cc17da 184 SUPERFAMILY SSF53335 1 181 4.57E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS12930 7be8fd0370a0c7aa4704f3b907cc17da 184 Gene3D G3DSA:3.40.50.150 1 184 5.7E-39 T 29-03-2018 CWR56_RS12885 e5ea2f7349bd2b7ad221c92057e31dad 305 Gene3D G3DSA:1.10.3720.10 71 302 1.5E-39 T 29-03-2018 CWR56_RS12885 e5ea2f7349bd2b7ad221c92057e31dad 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 300 2.0E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS12885 e5ea2f7349bd2b7ad221c92057e31dad 305 Gene3D G3DSA:1.20.58.370 12 54 1.7E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CWR56_RS12885 e5ea2f7349bd2b7ad221c92057e31dad 305 SUPERFAMILY SSF160964 22 61 6.28E-6 T 29-03-2018 CWR56_RS12885 e5ea2f7349bd2b7ad221c92057e31dad 305 SUPERFAMILY SSF161098 64 293 1.18E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 1 590 1.8E-216 T 29-03-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Gene3D G3DSA:3.40.50.970 1 235 8.7E-47 T 29-03-2018 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Pfam PF13187 4Fe-4S dicluster domain 544 590 8.8E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 575 586 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 SUPERFAMILY SSF52518 335 519 1.02E-30 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Gene3D G3DSA:3.40.50.970 360 520 1.2E-24 T 29-03-2018 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 PIRSF PIRSF006439 1 595 2.0E-228 T 29-03-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 SUPERFAMILY SSF52922 221 295 2.94E-7 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Gene3D G3DSA:3.30.70.20 547 595 3.4E-12 T 29-03-2018 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 SUPERFAMILY SSF52518 3 213 5.42E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Gene3D G3DSA:3.40.50.920 236 303 0.0098 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 186 5.8E-17 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Gene3D G3DSA:3.30.70.20 521 546 0.031 T 29-03-2018 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 SUPERFAMILY SSF54862 503 594 1.1E-13 T 29-03-2018 CWR56_RS12010 0e99db5aaec8b9b2ffa5224aa4178401 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 364 511 2.5E-27 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 Gene3D G3DSA:1.10.3100.10 1 94 6.6E-21 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 SMART SM00966 83 129 2.1E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 SMART SM00530 5 60 3.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 SUPERFAMILY SSF89447 80 116 3.31E-9 T 29-03-2018 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 Pfam PF01381 Helix-turn-helix 6 60 2.8E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 SUPERFAMILY SSF47413 2 66 2.53E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 83 118 4.4E-12 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CWR56_RS15585 8eb258e9ab270bbc819d60247995afc7 141 Gene3D G3DSA:2.10.260.10 95 124 9.1E-11 T 29-03-2018 CWR56_RS00515 9655bb870d2d322c10d6fb32db6f5151 279 Hamap MF_01499 Diadenylate cyclase [dacA]. 13 264 32.483 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CWR56_RS00515 9655bb870d2d322c10d6fb32db6f5151 279 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 17 266 5.7E-77 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CWR56_RS00515 9655bb870d2d322c10d6fb32db6f5151 279 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 128 246 2.3E-43 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR56_RS00515 9655bb870d2d322c10d6fb32db6f5151 279 SUPERFAMILY SSF143597 49 250 5.23E-65 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR56_RS00515 9655bb870d2d322c10d6fb32db6f5151 279 PIRSF PIRSF004793 12 274 2.5E-87 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CWR56_RS00515 9655bb870d2d322c10d6fb32db6f5151 279 Gene3D G3DSA:3.40.1700.10 121 249 7.6E-37 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR56_RS15690 31fc4a2e3caa06c87d00d289d0936f35 320 Gene3D G3DSA:1.10.10.10 1 64 8.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15690 31fc4a2e3caa06c87d00d289d0936f35 320 Pfam PF08279 HTH domain 9 60 4.1E-14 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS15690 31fc4a2e3caa06c87d00d289d0936f35 320 SUPERFAMILY SSF46785 3 63 4.08E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15690 31fc4a2e3caa06c87d00d289d0936f35 320 Pfam PF13280 WYL domain 139 313 6.1E-25 T 29-03-2018 IPR026881 WYL domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 SUPERFAMILY SSF141868 494 738 3.66E-86 T 29-03-2018 IPR001633 EAL domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 SMART SM00052 488 734 1.4E-99 T 29-03-2018 IPR001633 EAL domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Pfam PF00563 EAL domain 495 729 6.0E-73 T 29-03-2018 IPR001633 EAL domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Gene3D G3DSA:3.30.450.20 78 154 2.2E-9 T 29-03-2018 CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Gene3D G3DSA:3.30.70.270 317 484 8.9E-28 T 29-03-2018 CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 SMART SM00267 312 478 4.2E-13 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Pfam PF00990 Diguanylate cyclase, GGDEF domain 323 471 4.9E-20 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Gene3D G3DSA:3.20.20.450 485 736 1.6E-92 T 29-03-2018 IPR001633 EAL domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Pfam PF02743 Cache domain 52 258 1.3E-20 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 SUPERFAMILY SSF55073 329 477 4.87E-23 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 322 472 8.7E-16 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14750 4c407f685dad0b2dee2dcba8ce628443 739 Gene3D G3DSA:3.30.450.20 155 289 2.7E-15 T 29-03-2018 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 Gene3D G3DSA:1.10.10.250 72 140 2.8E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 Gene3D G3DSA:3.30.1550.10 3 71 3.9E-36 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 3.1E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 2.0E-14 T 29-03-2018 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 6.3E-63 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.1E-23 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 SMART SM00649 9 140 2.9E-84 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 SUPERFAMILY SSF54747 3 72 1.96E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 30.851 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00025 4290228bd7e750f5fe425be35a840704 141 SUPERFAMILY SSF46906 67 140 1.44E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 Gene3D G3DSA:3.40.50.620 3 159 7.7E-25 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 SUPERFAMILY SSF69864 173 396 1.26E-85 T 29-03-2018 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 398 50.555 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 395 9.8E-145 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 SUPERFAMILY SSF52402 2 166 9.31E-45 T 29-03-2018 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 Gene3D G3DSA:3.90.1260.10 160 353 3.2E-88 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 Gene3D G3DSA:1.20.5.470 365 396 2.7E-13 T 29-03-2018 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 Pfam PF00764 Arginosuccinate synthase 6 392 1.3E-154 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS08595 d296f5bf61dac08cb2517d123bc29490 399 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 SUPERFAMILY SSF46785 11 139 1.05E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 Pfam PF01047 MarR family 36 93 1.4E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 Gene3D G3DSA:1.10.10.10 25 123 3.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.6E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS02175 77984b0ee24f068930d8e70998e270b4 141 SMART SM00347 29 129 4.2E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 SUPERFAMILY SSF88659 176 256 1.59E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 Pfam PF04542 Sigma-70 region 2 42 110 5.8E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 256 9.8E-82 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 256 3.3E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 PIRSF PIRSF000770 11 257 1.3E-38 T 29-03-2018 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 PRINTS PR00046 Major sigma-70 factor signature 227 242 3.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 PRINTS PR00046 Major sigma-70 factor signature 66 79 3.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 PRINTS PR00046 Major sigma-70 factor signature 210 222 3.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 PRINTS PR00046 Major sigma-70 factor signature 242 253 3.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 PRINTS PR00046 Major sigma-70 factor signature 90 98 3.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 Gene3D G3DSA:1.10.1270.10 172 257 6.3E-17 T 29-03-2018 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.3E-142 T 29-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 Pfam PF04545 Sigma-70, region 4 206 255 4.2E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 Gene3D G3DSA:1.10.10.10 111 163 7.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 Gene3D G3DSA:1.10.601.10 11 110 1.5E-34 T 29-03-2018 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 SUPERFAMILY SSF88946 6 110 1.11E-35 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 SUPERFAMILY SSF88659 114 189 1.7E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS13370 ed2b8a8dddf27a131dbe0506459c5f68 257 Pfam PF04539 Sigma-70 region 3 124 176 6.8E-8 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS15405 4c71997fc22513ccfa6fabb60adf7178 384 Gene3D G3DSA:3.90.1510.10 42 276 4.6E-91 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CWR56_RS15405 4c71997fc22513ccfa6fabb60adf7178 384 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 9.3E-146 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR56_RS15405 4c71997fc22513ccfa6fabb60adf7178 384 SUPERFAMILY SSF110738 1 374 1.57E-127 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR56_RS15405 4c71997fc22513ccfa6fabb60adf7178 384 PIRSF PIRSF006078 1 380 2.3E-138 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR56_RS15405 4c71997fc22513ccfa6fabb60adf7178 384 Pfam PF02595 Glycerate kinase family 3 375 9.0E-144 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 Gene3D G3DSA:3.30.450.20 32 170 8.8E-16 T 29-03-2018 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 Gene3D G3DSA:3.30.565.10 313 472 2.7E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 470 6.7E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 SMART SM00304 197 251 1.4E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 Pfam PF00672 HAMP domain 199 246 1.3E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 SUPERFAMILY SSF47384 235 319 1.16E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 SUPERFAMILY SSF55874 308 470 6.02E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 SUPERFAMILY SSF158472 199 247 1.02E-6 T 29-03-2018 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 SMART SM00388 252 318 1.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 316 1.2E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 SMART SM00387 365 473 4.0E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS08585 b8aa5bfe507a7d6f1e4145d56fe24bf6 477 Gene3D G3DSA:1.10.287.130 242 312 6.9E-19 T 29-03-2018 CWR56_RS17400 8c035cece325aa0bc793ac91cf380763 590 SUPERFAMILY SSF55486 9 571 1.1E-95 T 29-03-2018 CWR56_RS17400 8c035cece325aa0bc793ac91cf380763 590 Pfam PF08439 Oligopeptidase F 121 187 3.5E-11 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CWR56_RS17400 8c035cece325aa0bc793ac91cf380763 590 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 19 589 8.6E-157 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CWR56_RS17400 8c035cece325aa0bc793ac91cf380763 590 Pfam PF01432 Peptidase family M3 202 576 1.0E-52 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWR56_RS17400 8c035cece325aa0bc793ac91cf380763 590 Gene3D G3DSA:1.10.287.830 187 220 0.0039 T 29-03-2018 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 SMART SM00465 14 96 1.4E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Gene3D G3DSA:4.10.860.10 183 245 1.7E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 599 28.55 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Pfam PF02151 UvrB/uvrC motif 205 239 4.0E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Gene3D G3DSA:3.40.1440.10 2 99 1.5E-25 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 581 5.1E-186 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Pfam PF12826 Helix-hairpin-helix motif 553 605 2.8E-12 T 29-03-2018 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 389 534 1.3E-45 T 29-03-2018 IPR001162 UvrC family homology region CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Pfam PF01541 GIY-YIG catalytic domain 15 91 2.3E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 Gene3D G3DSA:1.10.150.20 533 605 1.0E-17 T 29-03-2018 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 SUPERFAMILY SSF47781 503 604 1.56E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 SUPERFAMILY SSF82771 15 98 6.54E-25 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 SUPERFAMILY SSF46600 191 244 1.27E-11 T 29-03-2018 IPR001943 UVR domain GO:0005515 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 SMART SM00278 548 567 4.4 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS16975 fe197d74f5ac68697ed2565cc2a4fb91 605 SMART SM00278 580 599 12.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS13680 721e89887228f66cfbddeab9c5c74214 217 Pfam PF00805 Pentapeptide repeats (8 copies) 144 180 2.7E-4 T 29-03-2018 IPR001646 Pentapeptide repeat CWR56_RS13680 721e89887228f66cfbddeab9c5c74214 217 SUPERFAMILY SSF141571 42 216 2.75E-41 T 29-03-2018 CWR56_RS13680 721e89887228f66cfbddeab9c5c74214 217 Gene3D G3DSA:2.160.10.20 27 127 2.4E-15 T 29-03-2018 CWR56_RS13680 721e89887228f66cfbddeab9c5c74214 217 Gene3D G3DSA:2.160.10.20 128 216 2.8E-9 T 29-03-2018 CWR56_RS13680 721e89887228f66cfbddeab9c5c74214 217 Pfam PF13599 Pentapeptide repeats (9 copies) 54 123 1.1E-11 T 29-03-2018 IPR001646 Pentapeptide repeat CWR56_RS15800 474fc83b19efc310144dbfa888ce8ee4 254 Pfam PF01381 Helix-turn-helix 7 57 3.6E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15800 474fc83b19efc310144dbfa888ce8ee4 254 SUPERFAMILY SSF47413 2 67 1.05E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS15800 474fc83b19efc310144dbfa888ce8ee4 254 SMART SM00530 6 61 2.1E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15800 474fc83b19efc310144dbfa888ce8ee4 254 Gene3D G3DSA:1.10.260.40 1 251 3.2E-21 T 29-03-2018 CWR56_RS06305 941594ce44f1574715eb0a6b5b82978e 142 SMART SM00116 85 129 100.0 T 29-03-2018 IPR000644 CBS domain CWR56_RS06305 941594ce44f1574715eb0a6b5b82978e 142 SMART SM00116 12 60 4.9E-5 T 29-03-2018 IPR000644 CBS domain CWR56_RS06305 941594ce44f1574715eb0a6b5b82978e 142 SUPERFAMILY SSF54631 1 129 4.8E-31 T 29-03-2018 CWR56_RS06305 941594ce44f1574715eb0a6b5b82978e 142 Gene3D G3DSA:3.10.580.10 6 134 6.4E-20 T 29-03-2018 CWR56_RS06305 941594ce44f1574715eb0a6b5b82978e 142 Pfam PF00571 CBS domain 11 56 7.9E-10 T 29-03-2018 IPR000644 CBS domain CWR56_RS06305 941594ce44f1574715eb0a6b5b82978e 142 Pfam PF00571 CBS domain 75 127 1.4E-5 T 29-03-2018 IPR000644 CBS domain CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 Gene3D G3DSA:3.30.70.20 222 247 0.057 T 29-03-2018 CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 Pfam PF00037 4Fe-4S binding domain 186 204 9.4E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 SUPERFAMILY SSF54862 184 248 7.5E-14 T 29-03-2018 CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 Gene3D G3DSA:3.30.70.20 199 221 5.8E-8 T 29-03-2018 CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 SUPERFAMILY SSF52218 1 144 1.57E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS02180 a65ede5cd7e29802fe3db4e81bd56d23 259 Gene3D G3DSA:3.40.50.360 46 198 2.8E-22 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 Pfam PF00633 Helix-hairpin-helix motif 92 119 6.8E-9 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 Hamap MF_00942 Endonuclease III [nth]. 1 201 37.483 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 Gene3D G3DSA:1.10.340.30 13 109 2.2E-26 T 29-03-2018 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 SUPERFAMILY SSF48150 5 200 8.79E-71 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 160 2.5E-23 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 SMART SM00525 178 198 1.4E-4 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 Gene3D G3DSA:1.10.1670.10 110 205 1.6E-36 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 SMART SM00478 30 177 8.0E-58 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 TIGRFAM TIGR01083 nth: endonuclease III 1 186 1.2E-81 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 PIRSF PIRSF001435 1 204 6.5E-58 T 29-03-2018 CWR56_RS02610 36272f59c08e42a426a5e025f8e0ebf8 205 ProSitePatterns PS01155 Endonuclease III family signature. 94 123 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CWR56_RS07155 c90cb849e31f92490145484eeee1c648 275 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 264 43.588 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR56_RS07155 c90cb849e31f92490145484eeee1c648 275 PIRSF PIRSF000388 1 267 8.5E-116 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR56_RS07155 c90cb849e31f92490145484eeee1c648 275 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 264 2.4E-104 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR56_RS07155 c90cb849e31f92490145484eeee1c648 275 Gene3D G3DSA:3.20.20.60 1 264 4.9E-81 T 29-03-2018 CWR56_RS07155 c90cb849e31f92490145484eeee1c648 275 SUPERFAMILY SSF51621 3 264 1.44E-106 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR56_RS07155 c90cb849e31f92490145484eeee1c648 275 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 260 9.7E-115 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 469 1.0E-162 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 805 24.729 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Gene3D G3DSA:1.10.268.10 343 485 2.2E-54 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 757 803 1.4E-7 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 547 2.7E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 608 652 2.0E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 703 8.7E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 554 601 4.8E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 754 1.7E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Gene3D G3DSA:3.90.199.10 33 213 9.5E-84 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 803 0.0 T 29-03-2018 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 SUPERFAMILY SSF56719 30 485 5.49E-180 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 SMART SM00434 10 463 6.4E-287 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Gene3D G3DSA:2.120.10.90 494 805 1.2E-122 T 29-03-2018 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 Gene3D G3DSA:3.30.1360.40 235 330 3.9E-37 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR56_RS18465 b69ae58e3f1da3c8288c69a26b737f7c 808 SUPERFAMILY SSF101904 497 806 1.05E-107 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CWR56_RS12950 ef2e834374240e5b530ab32876aece88 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 6.7E-23 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12950 ef2e834374240e5b530ab32876aece88 62 Pfam PF00830 Ribosomal L28 family 3 58 7.2E-23 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12950 ef2e834374240e5b530ab32876aece88 62 Gene3D G3DSA:2.30.170.40 2 61 5.9E-21 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12950 ef2e834374240e5b530ab32876aece88 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.002 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12950 ef2e834374240e5b530ab32876aece88 62 SUPERFAMILY SSF143800 1 60 2.35E-23 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 SUPERFAMILY SSF52218 4 123 2.7E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 Gene3D G3DSA:3.30.70.20 171 200 8.8E-5 T 29-03-2018 CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 SUPERFAMILY SSF54862 181 238 2.37E-12 T 29-03-2018 CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 Gene3D G3DSA:3.40.50.360 1 151 2.8E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 Gene3D G3DSA:3.30.70.20 223 248 0.0099 T 29-03-2018 CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 Pfam PF00037 4Fe-4S binding domain 187 205 1.7E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS08460 452f9f362c4cf19b870f6dc186ff5a8d 253 Gene3D G3DSA:3.30.70.20 201 222 1.1E-6 T 29-03-2018 CWR56_RS12375 8d3cf085f7274b61e464ae6c7836dd90 252 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 10 248 5.0E-65 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS12375 8d3cf085f7274b61e464ae6c7836dd90 252 Pfam PF04452 RNA methyltransferase 19 241 5.3E-73 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS12375 8d3cf085f7274b61e464ae6c7836dd90 252 SUPERFAMILY SSF88697 1 72 5.96E-14 T 29-03-2018 IPR015947 PUA-like domain CWR56_RS12375 8d3cf085f7274b61e464ae6c7836dd90 252 PIRSF PIRSF015601 1 248 1.2E-65 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS12375 8d3cf085f7274b61e464ae6c7836dd90 252 Gene3D G3DSA:3.40.1280.10 1 252 1.2E-77 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR56_RS12375 8d3cf085f7274b61e464ae6c7836dd90 252 SUPERFAMILY SSF75217 74 248 4.36E-50 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Pfam PF08245 Mur ligase middle domain 107 287 1.2E-28 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 SUPERFAMILY SSF53623 88 304 4.32E-56 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 389 7.4E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 SUPERFAMILY SSF51984 1 85 3.14E-25 T 29-03-2018 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 SUPERFAMILY SSF53244 306 448 4.94E-42 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 2 446 2.8E-142 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Gene3D G3DSA:3.40.1190.10 90 307 3.2E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 450 35.821 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Gene3D G3DSA:3.40.50.720 1 89 2.3E-14 T 29-03-2018 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Pfam PF01225 Mur ligase family, catalytic domain 3 101 2.6E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR56_RS17545 49c9842f388e5fefc64d07285872dc2c 450 Gene3D G3DSA:3.90.190.20 308 450 1.4E-35 T 29-03-2018 CWR56_RS13755 d09fae87b582274c36f0a8cf56bfcfad 847 SUPERFAMILY SSF110997 718 790 2.35E-11 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CWR56_RS13755 d09fae87b582274c36f0a8cf56bfcfad 847 Pfam PF05036 Sporulation related domain 720 783 6.8E-9 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CWR56_RS13755 d09fae87b582274c36f0a8cf56bfcfad 847 Gene3D G3DSA:3.30.70.1070 718 789 1.2E-9 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CWR56_RS13755 d09fae87b582274c36f0a8cf56bfcfad 847 Gene3D G3DSA:1.20.920.10 70 714 2.8E-7 T 29-03-2018 IPR001487 Bromodomain GO:0005515 CWR56_RS08285 45aa637f2f3cf9ff743c1b0c6ad999f4 79 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 29 71 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS08285 45aa637f2f3cf9ff743c1b0c6ad999f4 79 Pfam PF12833 Helix-turn-helix domain 12 75 1.0E-11 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS08285 45aa637f2f3cf9ff743c1b0c6ad999f4 79 SUPERFAMILY SSF46689 28 76 2.29E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08285 45aa637f2f3cf9ff743c1b0c6ad999f4 79 SMART SM00342 2 75 1.6E-6 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS08285 45aa637f2f3cf9ff743c1b0c6ad999f4 79 Gene3D G3DSA:2.60.120.10 7 32 6.9E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS08285 45aa637f2f3cf9ff743c1b0c6ad999f4 79 Gene3D G3DSA:1.10.10.60 33 78 1.4E-10 T 29-03-2018 CWR56_RS02515 b1e90cf5f4f3a3355090c3220796ae59 119 Pfam PF03965 Penicillinase repressor 7 116 5.9E-27 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS02515 b1e90cf5f4f3a3355090c3220796ae59 119 Gene3D G3DSA:1.10.10.10 7 73 2.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02515 b1e90cf5f4f3a3355090c3220796ae59 119 Gene3D G3DSA:1.10.4040.10 74 117 7.9E-16 T 29-03-2018 CWR56_RS02515 b1e90cf5f4f3a3355090c3220796ae59 119 SUPERFAMILY SSF46785 4 118 3.18E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02515 b1e90cf5f4f3a3355090c3220796ae59 119 PIRSF PIRSF019455 1 119 6.8E-35 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 Gene3D G3DSA:3.40.190.10 86 176 6.6E-18 T 29-03-2018 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 Gene3D G3DSA:3.40.190.10 177 263 8.5E-17 T 29-03-2018 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 SUPERFAMILY SSF46785 2 79 3.63E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 Gene3D G3DSA:1.10.10.10 1 83 9.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 Pfam PF03466 LysR substrate binding domain 88 290 1.6E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 SUPERFAMILY SSF53850 89 291 1.32E-34 T 29-03-2018 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13720 30407fb9347361c93a43a1be42d6c9e8 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 Gene3D G3DSA:1.10.1040.10 182 281 1.7E-33 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 SUPERFAMILY SSF48179 182 281 1.19E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 PIRSF PIRSF000105 1 281 2.5E-91 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 SUPERFAMILY SSF51735 2 180 5.21E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 180 2.4E-64 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 279 1.2E-35 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 180 205 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CWR56_RS04865 d6a5850986f6724c513d4846f2cef6da 281 Gene3D G3DSA:3.40.50.720 1 181 3.2E-51 T 29-03-2018 CWR56_RS06450 b93b8e54de376babd125b6331d025f82 180 Gene3D G3DSA:1.10.10.60 7 41 1.1E-12 T 29-03-2018 CWR56_RS06450 b93b8e54de376babd125b6331d025f82 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS06450 b93b8e54de376babd125b6331d025f82 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS06450 b93b8e54de376babd125b6331d025f82 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS06450 b93b8e54de376babd125b6331d025f82 180 SUPERFAMILY SSF46689 6 70 9.22E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS06450 b93b8e54de376babd125b6331d025f82 180 Gene3D G3DSA:1.10.260.40 42 142 1.6E-9 T 29-03-2018 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 SUPERFAMILY SSF63520 201 294 2.62E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Pfam PF00874 PRD domain 331 408 6.5E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Pfam PF00874 PRD domain 210 294 1.5E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 SUPERFAMILY SSF52794 419 500 9.94E-11 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 SUPERFAMILY SSF63520 320 412 1.83E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Gene3D G3DSA:1.10.10.10 4 70 2.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Gene3D G3DSA:1.10.10.10 88 157 4.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Pfam PF08279 HTH domain 94 151 1.8E-8 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Gene3D G3DSA:1.10.1790.10 198 296 6.2E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Gene3D G3DSA:3.40.930.10 512 655 1.1E-30 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 SUPERFAMILY SSF46785 9 49 4.03E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 SUPERFAMILY SSF46785 90 151 6.65E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 518 651 8.4E-26 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Gene3D G3DSA:1.10.1790.10 297 413 2.2E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Pfam PF05043 Mga helix-turn-helix domain 9 65 5.8E-7 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 SUPERFAMILY SSF55804 514 653 3.27E-28 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15040 7dfe3e1f2128db53a54a96c82a9fa8eb 656 Gene3D G3DSA:3.40.50.2300 417 505 1.4E-18 T 29-03-2018 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 SUPERFAMILY SSF53850 89 296 2.72E-29 T 29-03-2018 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 Gene3D G3DSA:3.40.190.10 90 175 9.9E-12 T 29-03-2018 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 Gene3D G3DSA:3.40.190.10 176 265 1.5E-12 T 29-03-2018 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 SUPERFAMILY SSF46785 1 87 2.88E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 Pfam PF03466 LysR substrate binding domain 87 293 5.4E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 Gene3D G3DSA:1.10.10.10 1 89 2.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04990 4f1cbea0e5bfd7f8df3cc0cf988f46ac 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.9E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 Gene3D G3DSA:3.40.50.450 1 206 4.9E-86 T 29-03-2018 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 Gene3D G3DSA:3.40.50.450 207 300 4.4E-18 T 29-03-2018 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 3.5E-86 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 46.659 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 Pfam PF00365 Phosphofructokinase 4 275 3.0E-112 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 299 1.9E-131 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 PIRSF PIRSF000532 1 319 3.4E-123 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWR56_RS16900 1c7889dab3b35de3018d99f4382b9b27 319 SUPERFAMILY SSF53784 1 316 8.63E-120 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 SUPERFAMILY SSF53850 46 268 2.18E-49 T 29-03-2018 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 Pfam PF13531 Bacterial extracellular solute-binding protein 50 267 3.3E-42 T 29-03-2018 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 Gene3D G3DSA:3.40.190.10 207 270 8.9E-5 T 29-03-2018 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 PIRSF PIRSF004846 1 270 1.2E-53 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 54 265 1.4E-26 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 SMART SM00062 47 268 5.3E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 Gene3D G3DSA:3.40.190.10 40 134 1.1E-17 T 29-03-2018 CWR56_RS11485 df498c1e3d5d3700c4ea0b14af0451a7 270 Gene3D G3DSA:3.40.190.10 135 206 1.3E-11 T 29-03-2018 CWR56_RS18340 77bc65235bae77a6ee16b94a6e821153 144 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 144 1.7E-32 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR56_RS18340 77bc65235bae77a6ee16b94a6e821153 144 PIRSF PIRSF002070 1 144 5.0E-34 T 29-03-2018 CWR56_RS18340 77bc65235bae77a6ee16b94a6e821153 144 Pfam PF00436 Single-strand binding protein family 1 102 5.4E-29 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWR56_RS18340 77bc65235bae77a6ee16b94a6e821153 144 Hamap MF_00984 Single-stranded DNA-binding protein. 1 107 28.985 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR56_RS18340 77bc65235bae77a6ee16b94a6e821153 144 Gene3D G3DSA:2.40.50.140 1 111 7.3E-35 T 29-03-2018 CWR56_RS18340 77bc65235bae77a6ee16b94a6e821153 144 SUPERFAMILY SSF50249 1 144 2.16E-41 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 Pfam PF13102 Phage integrase SAM-like domain 90 175 7.5E-6 T 29-03-2018 IPR025269 Phage integrase SAM-like domain CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 Gene3D G3DSA:1.10.443.10 187 396 3.0E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 Gene3D G3DSA:3.30.160.60 6 71 2.9E-24 T 29-03-2018 CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 SUPERFAMILY SSF54171 5 74 5.1E-30 T 29-03-2018 IPR016177 DNA-binding domain GO:0003677 CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 SUPERFAMILY SSF56349 94 386 2.12E-48 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 Pfam PF00589 Phage integrase family 192 383 1.1E-37 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 Pfam PF02920 DNA binding domain of tn916 integrase 4 72 3.0E-25 T 29-03-2018 IPR004191 Integrase, Tn916-type, N-terminal DNA binding GO:0003677|GO:0008907|GO:0015074 CWR56_RS10895 c1908fb87a121ae9f596ee6263316008 396 Gene3D G3DSA:1.10.150.130 78 186 1.7E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 SUPERFAMILY SSF74650 11 267 2.17E-48 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 PIRSF PIRSF036289 1 787 3.7E-216 T 29-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 350 727 3.2E-124 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 13 269 9.2E-56 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 Gene3D G3DSA:2.60.420.10 713 784 1.9E-17 T 29-03-2018 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 SUPERFAMILY SSF48208 307 779 8.96E-127 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 Gene3D G3DSA:1.50.10.10 343 712 1.3E-110 T 29-03-2018 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 Gene3D G3DSA:2.70.98.40 5 272 8.3E-56 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CWR56_RS15635 4b3a844faf266fcf8399fef5cd68ffe9 796 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 731 781 6.7E-9 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CWR56_RS15000 543913d336a3ac4665c470e214cbcf22 234 Pfam PF04256 Protein of unknown function (DUF434) 21 76 2.8E-19 T 29-03-2018 IPR007368 Protein of unknown function DUF434 CWR56_RS15000 543913d336a3ac4665c470e214cbcf22 234 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 22 66 1.0E-6 T 29-03-2018 IPR007368 Protein of unknown function DUF434 CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 Gene3D G3DSA:3.30.190.20 146 225 8.4E-21 T 29-03-2018 CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.0E-102 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 230 44.288 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 SUPERFAMILY SSF56808 6 226 4.32E-84 T 29-03-2018 IPR023674 Ribosomal protein L1-like CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 PIRSF PIRSF002155 1 228 1.7E-79 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 Gene3D G3DSA:3.40.50.790 68 145 2.4E-37 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CWR56_RS00030 65bac3d022066ac89b9127002732f33d 232 Pfam PF00687 Ribosomal protein L1p/L10e family 35 221 2.3E-57 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 357 1.0E-22 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 362 1.1E-121 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 378 824 48.887 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Gene3D G3DSA:3.30.1360.120 4 135 8.5E-32 T 29-03-2018 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 258 3.8E-94 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Gene3D G3DSA:3.40.640.10 459 713 9.0E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 363 44.648 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Gene3D G3DSA:2.40.30.110 282 373 1.6E-24 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Gene3D G3DSA:4.10.1250.10 239 280 4.4E-11 T 29-03-2018 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Gene3D G3DSA:3.90.1150.10 714 824 6.6E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 SUPERFAMILY SSF103025 3 281 6.12E-93 T 29-03-2018 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Pfam PF02347 Glycine cleavage system P-protein 379 820 7.7E-145 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 SUPERFAMILY SSF53383 379 822 1.09E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 Gene3D G3DSA:3.30.1360.120 136 237 1.6E-26 T 29-03-2018 CWR56_RS07900 582933c033c5c485031cb6c50e78680c 824 SUPERFAMILY SSF101790 275 367 3.6E-23 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Gene3D G3DSA:1.10.1790.10 283 398 8.1E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Pfam PF05043 Mga helix-turn-helix domain 86 162 5.0E-6 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Gene3D G3DSA:1.10.10.10 4 66 5.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 SUPERFAMILY SSF63520 275 398 3.14E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Gene3D G3DSA:3.40.50.2300 405 516 5.7E-13 T 29-03-2018 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Gene3D G3DSA:3.40.930.10 547 694 8.6E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 551 691 3.7E-35 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Pfam PF00874 PRD domain 310 393 2.3E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 SUPERFAMILY SSF52794 411 493 1.05E-9 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 SUPERFAMILY SSF55804 547 691 2.09E-37 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS18135 a08a74b8a5cd904e01838692e91bd6fb 695 Gene3D G3DSA:1.10.10.10 70 154 2.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 Gene3D G3DSA:2.30.40.10 449 520 1.2E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 SUPERFAMILY SSF51338 3 57 3.7E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 SUPERFAMILY SSF51338 468 521 3.7E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 Gene3D G3DSA:2.30.40.10 2 70 1.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 SUPERFAMILY SSF51556 57 292 5.99E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 SUPERFAMILY SSF51556 330 468 5.99E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 Pfam PF07969 Amidohydrolase family 443 515 8.6E-9 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 Pfam PF07969 Amidohydrolase family 45 227 1.5E-10 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS14530 a820f9d98d7c74310dc84fa77d3c38a5 533 Gene3D G3DSA:3.20.20.140 71 448 8.5E-57 T 29-03-2018 CWR56_RS06140 e00d67272181bc97bf83a78480e87c1f 81 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 76 4.3E-24 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CWR56_RS06140 e00d67272181bc97bf83a78480e87c1f 81 Pfam PF05239 PRC-barrel domain 2 76 2.8E-12 T 29-03-2018 IPR027275 PRC-barrel domain CWR56_RS06140 e00d67272181bc97bf83a78480e87c1f 81 SUPERFAMILY SSF50346 2 75 2.98E-11 T 29-03-2018 IPR011033 PRC-barrel-like CWR56_RS06140 e00d67272181bc97bf83a78480e87c1f 81 Gene3D G3DSA:2.30.30.240 1 79 1.7E-14 T 29-03-2018 CWR56_RS13225 53413eb327b38886c642e5dc76e3ee6a 290 PIRSF PIRSF006483 1 290 4.1E-103 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS13225 53413eb327b38886c642e5dc76e3ee6a 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 17 223 3.8E-56 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS13225 53413eb327b38886c642e5dc76e3ee6a 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 228 282 5.1E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 392 40.775 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 PIRSF PIRSF000521 5 164 1.9E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 PIRSF PIRSF000521 169 394 1.3E-37 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 391 2.8E-140 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 Gene3D G3DSA:3.90.1150.10 1 175 1.5E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 Pfam PF00202 Aminotransferase class-III 21 391 5.6E-108 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 SUPERFAMILY SSF53383 10 391 2.48E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 Gene3D G3DSA:3.40.640.10 176 289 1.2E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS09705 d06f85f35e02ecf0cd15ba6ade5adf21 395 Gene3D G3DSA:3.90.1150.10 290 395 1.9E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS04440 2b3ab7ac00b8140589d1d7d34e86b867 380 SUPERFAMILY SSF51430 1 306 3.54E-42 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS04440 2b3ab7ac00b8140589d1d7d34e86b867 380 Pfam PF13534 4Fe-4S dicluster domain 286 359 1.6E-9 T 29-03-2018 CWR56_RS04440 2b3ab7ac00b8140589d1d7d34e86b867 380 Gene3D G3DSA:1.10.1060.10 255 379 1.6E-10 T 29-03-2018 CWR56_RS04440 2b3ab7ac00b8140589d1d7d34e86b867 380 Gene3D G3DSA:3.20.20.100 1 254 1.2E-35 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS04440 2b3ab7ac00b8140589d1d7d34e86b867 380 Pfam PF00248 Aldo/keto reductase family 16 228 3.0E-19 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS04440 2b3ab7ac00b8140589d1d7d34e86b867 380 SUPERFAMILY SSF46548 279 364 6.28E-8 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR56_RS07090 f8f165ec53bde07e1c984216875f53b7 122 Gene3D G3DSA:1.10.10.10 1 76 2.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07090 f8f165ec53bde07e1c984216875f53b7 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 6.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS07090 f8f165ec53bde07e1c984216875f53b7 122 SMART SM00345 15 74 2.5E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS07090 f8f165ec53bde07e1c984216875f53b7 122 Gene3D G3DSA:1.10.287.100 77 118 1.4E-10 T 29-03-2018 CWR56_RS07090 f8f165ec53bde07e1c984216875f53b7 122 SUPERFAMILY SSF46785 7 82 1.04E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 SUPERFAMILY SSF54862 165 324 3.53E-27 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Gene3D G3DSA:3.30.70.20 176 222 5.4E-12 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 307 318 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Pfam PF14697 4Fe-4S dicluster domain 271 323 1.1E-11 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Gene3D G3DSA:3.30.70.20 283 325 1.4E-13 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Gene3D G3DSA:3.30.70.20 250 282 2.5E-14 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Pfam PF00037 4Fe-4S binding domain 165 186 2.3E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 5 103 4.8E-21 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Gene3D G3DSA:3.30.70.20 25 148 2.2E-4 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Gene3D G3DSA:3.30.70.20 149 175 1.0E-11 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Gene3D G3DSA:3.30.70.20 223 249 1.6E-13 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 245 256 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Pfam PF12838 4Fe-4S dicluster domain 216 259 2.4E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 SUPERFAMILY SSF54862 39 192 3.49E-11 T 29-03-2018 CWR56_RS05180 bbffaf182aaf9ee80f387ae2371e9a1d 325 Pfam PF04060 Putative Fe-S cluster 45 77 1.4E-12 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 TIGRFAM TIGR00033 aroC: chorismate synthase 9 356 7.0E-119 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 Hamap MF_00300 Chorismate synthase [aroC]. 9 358 33.144 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 Gene3D G3DSA:3.60.150.10 8 358 1.3E-137 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 ProSitePatterns PS00789 Chorismate synthase signature 3. 331 347 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 PIRSF PIRSF001456 2 359 2.5E-141 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 Pfam PF01264 Chorismate synthase 9 356 2.0E-127 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS08855 acc83245db95b626e0f99d86b3b29efe 359 SUPERFAMILY SSF103263 4 356 9.68E-120 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 Gene3D G3DSA:1.10.40.50 227 294 3.4E-19 T 29-03-2018 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 Pfam PF03193 RsgA GTPase 62 225 8.7E-57 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 SUPERFAMILY SSF50249 1 64 7.54E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 290 35.462 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 1.9E-72 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 Pfam PF16745 RsgA N-terminal domain 3 56 5.5E-22 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 Gene3D G3DSA:3.40.50.300 65 225 1.6E-25 T 29-03-2018 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 Gene3D G3DSA:2.40.50.140 1 63 2.4E-22 T 29-03-2018 CWR56_RS13025 0ef9041a0d0d6bf7233684820c5f0599 294 SUPERFAMILY SSF52540 67 288 7.95E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 Gene3D G3DSA:1.10.287.130 240 297 5.4E-14 T 29-03-2018 CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 SMART SM00388 253 316 1.6E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 SUPERFAMILY SSF55874 305 462 5.5E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 Gene3D G3DSA:3.30.565.10 298 463 3.9E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 SUPERFAMILY SSF47384 238 314 3.73E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 Gene3D G3DSA:1.20.120.550 1 48 0.11 T 29-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 462 1.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 315 2.4E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 SMART SM00387 362 463 1.0E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 1.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS04615 2bafcdbf5f6b94db24d83c6c1f9bacf6 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 1.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 Gene3D G3DSA:1.10.10.10 121 230 6.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 Pfam PF00072 Response regulator receiver domain 5 113 9.5E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 SMART SM00448 3 113 7.4E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 1.1E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 SUPERFAMILY SSF46894 128 228 1.87E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 SUPERFAMILY SSF52172 2 125 6.26E-42 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 Gene3D G3DSA:3.40.50.2300 1 120 1.6E-37 T 29-03-2018 CWR56_RS17980 e67a166d83f1f72b90918f79a1b2d8fe 230 SMART SM00862 152 228 3.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 Gene3D G3DSA:2.40.50.110 4 73 1.4E-17 T 29-03-2018 CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 Gene3D G3DSA:2.40.50.110 74 132 3.1E-14 T 29-03-2018 CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 Pfam PF03734 L,D-transpeptidase catalytic domain 163 282 1.2E-17 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 Pfam PF08239 Bacterial SH3 domain 22 72 6.2E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 Pfam PF08239 Bacterial SH3 domain 79 130 4.1E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 Gene3D G3DSA:2.40.440.10 155 283 4.9E-24 T 29-03-2018 CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 SUPERFAMILY SSF141523 161 282 1.96E-22 T 29-03-2018 CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 SMART SM00287 13 74 2.7E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS14995 f6567fe7a98dc53633fc5c6d83d739ff 283 SMART SM00287 75 133 0.077 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 SMART SM01230 148 431 2.6E-39 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 Pfam PF00120 Glutamine synthetase, catalytic domain 170 442 4.3E-36 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 Gene3D G3DSA:3.30.590.10 129 541 3.8E-63 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 Gene3D G3DSA:3.10.20.70 14 100 5.8E-5 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 SUPERFAMILY SSF55931 127 440 8.44E-54 T 29-03-2018 CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 SUPERFAMILY SSF55931 467 528 8.44E-54 T 29-03-2018 CWR56_RS06240 d30a324346ecea71068b5c7bb39eba2c 632 SUPERFAMILY SSF54368 15 95 4.19E-5 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR56_RS11675 87e36d5f94c98253add6c93a21eb1eb0 510 SUPERFAMILY SSF53901 183 289 5.5E-13 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS11675 87e36d5f94c98253add6c93a21eb1eb0 510 Gene3D G3DSA:3.40.47.10 191 305 1.9E-7 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS11675 87e36d5f94c98253add6c93a21eb1eb0 510 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 253 331 5.5E-8 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR56_RS11675 87e36d5f94c98253add6c93a21eb1eb0 510 PIRSF PIRSF037559 1 510 9.0E-257 T 29-03-2018 IPR017236 Glycine/sarcosine/betaine reductase, component C, beta CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 SUPERFAMILY SSF54686 1 139 6.15E-60 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.1E-60 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.8E-52 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 40.182 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 Gene3D G3DSA:3.90.1170.10 2 139 6.3E-54 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.2E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.2E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.2E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00120 4c0e476de14134eab7ebb84334693bcc 143 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.2E-38 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS02640 008cf93212236b3ccafd145b481f0e8e 272 Pfam PF08812 YtxC-like family 61 267 3.3E-53 T 29-03-2018 IPR014199 Sporulation protein YtxC CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 1.5E-62 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 SUPERFAMILY SSF55120 1 245 3.02E-78 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 6.8E-30 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 Pfam PF01416 tRNA pseudouridine synthase 7 105 1.4E-7 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 Gene3D G3DSA:3.30.70.660 107 244 1.4E-42 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 PIRSF PIRSF001430 1 245 1.2E-77 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 Gene3D G3DSA:3.30.70.580 1 106 5.9E-27 T 29-03-2018 CWR56_RS08590 452a603cfb75110f8f8bdbe57fbe7717 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.544 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS17430 de61a834f957a2320f1cde225eee88e2 80 SUPERFAMILY SSF55174 1 77 4.32E-20 T 29-03-2018 CWR56_RS17430 de61a834f957a2320f1cde225eee88e2 80 Gene3D G3DSA:3.10.290.10 1 80 5.9E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS17430 de61a834f957a2320f1cde225eee88e2 80 Pfam PF01479 S4 domain 1 46 2.0E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS17430 de61a834f957a2320f1cde225eee88e2 80 PIRSF PIRSF038881 1 80 7.7E-33 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type CWR56_RS17430 de61a834f957a2320f1cde225eee88e2 80 SMART SM00363 1 64 9.0E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS05965 84673005138cc9df307778015c3e565b 152 Pfam PF01475 Ferric uptake regulator family 14 138 2.0E-36 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CWR56_RS05965 84673005138cc9df307778015c3e565b 152 SUPERFAMILY SSF46785 9 142 6.87E-39 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05965 84673005138cc9df307778015c3e565b 152 Gene3D G3DSA:1.10.10.10 8 98 1.9E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 364 370 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Gene3D G3DSA:1.20.1110.10 677 914 9.4E-58 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 656 672 2.3E-14 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 503 521 2.3E-14 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 688 713 2.3E-14 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Pfam PF13246 Cation transport ATPase (P-type) 403 486 1.9E-18 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Gene3D G3DSA:3.40.50.1000 552 676 1.2E-17 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Gene3D G3DSA:2.70.150.10 17 244 1.2E-43 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 362 376 1.7E-36 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 1.7E-36 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 1.7E-36 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 680 692 1.7E-36 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 675 1.7E-36 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 1.7E-36 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 288 392 1.3E-21 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 200 2.6E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 626 737 1.4E-32 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Pfam PF00689 Cation transporting ATPase, C-terminus 741 908 9.9E-37 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Gene3D G3DSA:3.40.1110.10 326 551 1.9E-50 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF81665 706 912 1.44E-107 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF81665 243 356 1.44E-107 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF81665 7 120 1.44E-107 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 77 9.4E-18 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SMART SM00831 8 82 8.0E-17 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF81653 121 241 4.05E-27 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Pfam PF00122 E1-E2 ATPase 122 341 1.0E-43 T 29-03-2018 CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 Pfam PF08282 haloacid dehalogenase-like hydrolase 640 698 9.8E-5 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF56784 475 515 8.65E-55 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF56784 360 380 8.65E-55 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 SUPERFAMILY SSF56784 544 761 8.65E-55 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07795 87e82721639cae7a3f5c15d86558b1aa 919 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 210 909 6.3E-164 T 29-03-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 CWR56_RS06205 2b6cca098609c1a97ce6d8ca0b8aa799 302 Gene3D G3DSA:1.10.443.10 111 281 3.3E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS06205 2b6cca098609c1a97ce6d8ca0b8aa799 302 Gene3D G3DSA:1.10.150.130 4 110 5.2E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS06205 2b6cca098609c1a97ce6d8ca0b8aa799 302 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 20 89 1.3E-6 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR56_RS06205 2b6cca098609c1a97ce6d8ca0b8aa799 302 SUPERFAMILY SSF56349 19 276 4.41E-47 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS06205 2b6cca098609c1a97ce6d8ca0b8aa799 302 Pfam PF00589 Phage integrase family 112 277 5.2E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS08740 ccc7983760b97f540305c9aa989f83d3 113 Pfam PF04397 LytTr DNA-binding domain 14 104 1.3E-10 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS08740 ccc7983760b97f540305c9aa989f83d3 113 SMART SM00850 13 106 2.1E-11 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS08740 ccc7983760b97f540305c9aa989f83d3 113 Gene3D G3DSA:2.40.50.40 3 73 5.2E-14 T 29-03-2018 CWR56_RS00540 486444c46f7fe5cf29ba9d7ec4dcb889 225 Gene3D G3DSA:3.40.50.300 3 98 0.003 T 29-03-2018 CWR56_RS00540 486444c46f7fe5cf29ba9d7ec4dcb889 225 Gene3D G3DSA:3.40.50.300 99 214 0.024 T 29-03-2018 CWR56_RS00540 486444c46f7fe5cf29ba9d7ec4dcb889 225 SUPERFAMILY SSF52540 3 201 1.14E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10450 5e19cd81158e93a75693a753c257d115 307 SUPERFAMILY SSF52151 12 295 3.14E-38 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR56_RS10450 5e19cd81158e93a75693a753c257d115 307 Pfam PF01734 Patatin-like phospholipase 15 185 1.3E-17 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CWR56_RS10450 5e19cd81158e93a75693a753c257d115 307 Gene3D G3DSA:3.40.1090.10 7 294 2.0E-51 T 29-03-2018 CWR56_RS17420 7398b71b7cd9c835100053459a6eea94 177 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 13 89 3.4E-14 T 29-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like CWR56_RS10365 92eecdd836d3697c2f3c62c6f67064b1 386 Pfam PF05684 Protein of unknown function (DUF819) 10 385 1.4E-91 T 29-03-2018 IPR008537 Protein of unknown function DUF819 CWR56_RS10295 757c4290d879f1ba8f2ed8fbefba6ffe 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.9E-70 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CWR56_RS10295 757c4290d879f1ba8f2ed8fbefba6ffe 185 Pfam PF01765 Ribosome recycling factor 21 183 8.9E-68 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CWR56_RS10295 757c4290d879f1ba8f2ed8fbefba6ffe 185 Gene3D G3DSA:1.10.132.20 75 184 1.1E-39 T 29-03-2018 CWR56_RS10295 757c4290d879f1ba8f2ed8fbefba6ffe 185 Gene3D G3DSA:1.10.132.20 3 74 8.2E-10 T 29-03-2018 CWR56_RS10295 757c4290d879f1ba8f2ed8fbefba6ffe 185 SUPERFAMILY SSF55194 5 184 3.4E-72 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CWR56_RS10295 757c4290d879f1ba8f2ed8fbefba6ffe 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.895 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Gene3D G3DSA:3.30.365.10 278 436 5.0E-42 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Gene3D G3DSA:3.90.1170.50 1 130 1.2E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 SUPERFAMILY SSF56003 122 752 1.44E-177 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 SMART SM01008 18 130 5.4E-41 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Gene3D G3DSA:3.30.365.10 450 597 1.3E-38 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 SUPERFAMILY SSF54665 2 149 6.41E-40 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 161 692 1.4E-157 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Gene3D G3DSA:3.30.365.10 598 754 3.5E-43 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 129 2.1E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10075 76d3f60895d373dbc25395c57af9e188 754 Gene3D G3DSA:3.30.365.10 171 277 2.6E-31 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 SUPERFAMILY SSF63520 58 167 1.31E-31 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 SUPERFAMILY SSF50151 1 54 1.07E-16 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 SUPERFAMILY SSF63520 172 273 1.7E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 Gene3D G3DSA:2.30.24.10 1 57 6.3E-22 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 Gene3D G3DSA:1.10.1790.10 58 164 1.1E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 Gene3D G3DSA:1.10.1790.10 165 277 3.0E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 Pfam PF03123 CAT RNA binding domain 1 54 1.2E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 SMART SM01061 1 59 1.8E-27 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 Pfam PF00874 PRD domain 181 272 4.8E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15475 d8645fb8c2133d200e1553401aa41673 286 Pfam PF00874 PRD domain 76 163 1.2E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS09250 4dc2d2923a11c1501b09012d8c6bcc70 106 Gene3D G3DSA:2.60.300.12 2 104 3.9E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR56_RS09250 4dc2d2923a11c1501b09012d8c6bcc70 106 SUPERFAMILY SSF89360 1 77 6.67E-10 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 Gene3D G3DSA:1.10.240.10 192 311 5.0E-30 T 29-03-2018 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 SUPERFAMILY SSF52374 6 328 1.33E-97 T 29-03-2018 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 Pfam PF00579 tRNA synthetases class I (W and Y) 6 283 3.4E-81 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 4 329 41.913 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 5.7E-30 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 196 206 5.7E-30 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 17 33 5.7E-30 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 5.7E-30 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 Gene3D G3DSA:3.40.50.620 1 191 5.8E-78 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS13190 025d310ccfaa6b40ff2d7cbc93ccfe3e 333 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 328 2.9E-113 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 371 87.141 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 361 1.0E-101 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 ProSitePatterns PS00618 RecF protein signature 2. 308 326 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 Gene3D G3DSA:3.40.50.300 2 366 2.2E-28 T 29-03-2018 CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 354 6.6E-18 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 SUPERFAMILY SSF52540 240 364 4.85E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18455 4fee7a5ba23fb406b005b2591c60c579 371 SUPERFAMILY SSF52540 2 213 4.85E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 Gene3D G3DSA:3.40.1190.20 2 296 1.0E-69 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 SUPERFAMILY SSF53613 4 294 1.71E-73 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 237 250 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 PRINTS PR00990 Ribokinase signature 172 187 1.0E-29 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 PRINTS PR00990 Ribokinase signature 6 27 1.0E-29 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 PRINTS PR00990 Ribokinase signature 208 219 1.0E-29 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 PRINTS PR00990 Ribokinase signature 33 52 1.0E-29 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 PRINTS PR00990 Ribokinase signature 104 117 1.0E-29 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 Pfam PF00294 pfkB family carbohydrate kinase 1 284 3.7E-63 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 290 6.1E-98 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CWR56_RS01540 0d1e51263e56a237320221a04140972e 296 Hamap MF_01987 Ribokinase [rbsK]. 2 292 23.239 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CWR56_RS01240 3635c9644e393f1a13982e3c4c060220 135 Pfam PF05523 WxcM-like, C-terminal 3 132 1.4E-46 T 29-03-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 CWR56_RS01240 3635c9644e393f1a13982e3c4c060220 135 SUPERFAMILY SSF51182 6 133 6.84E-39 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS01240 3635c9644e393f1a13982e3c4c060220 135 Gene3D G3DSA:2.60.120.10 2 135 1.6E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS16110 82df4d1c62e678edbebfd92879cb60ce 459 PIRSF PIRSF006603 1 452 2.6E-83 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS16110 82df4d1c62e678edbebfd92879cb60ce 459 Pfam PF01554 MatE 16 177 1.6E-25 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS16110 82df4d1c62e678edbebfd92879cb60ce 459 Pfam PF01554 MatE 239 404 3.2E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07240 611fd55bdd3d050f8981325f59f37987 409 Gene3D G3DSA:2.40.50.100 94 208 3.6E-6 T 29-03-2018 CWR56_RS07240 611fd55bdd3d050f8981325f59f37987 409 Pfam PF13437 HlyD family secretion protein 197 296 1.4E-4 T 29-03-2018 CWR56_RS07240 611fd55bdd3d050f8981325f59f37987 409 SUPERFAMILY SSF111369 116 243 7.45E-7 T 29-03-2018 CWR56_RS08890 4d17ced68708c637ca9f1471c44aab40 248 Pfam PF02698 DUF218 domain 91 238 2.6E-26 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CWR56_RS08890 4d17ced68708c637ca9f1471c44aab40 248 Gene3D G3DSA:3.40.50.620 82 225 4.1E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 23 264 2.4E-35 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 Gene3D G3DSA:2.40.37.10 255 403 1.7E-27 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 Gene3D G3DSA:3.20.20.10 21 254 2.6E-39 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 62 74 3.1E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 255 274 3.1E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 168 181 3.1E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 42 60 3.1E-11 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 17 374 1.1E-13 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 SUPERFAMILY SSF51419 14 265 1.34E-51 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS08715 8c3ea481de3b0e43a6a3155a01683a1c 403 SUPERFAMILY SSF50621 247 401 3.35E-30 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 SMART SM00354 2 73 5.1E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 Gene3D G3DSA:1.10.260.40 3 56 6.6E-20 T 29-03-2018 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 Gene3D G3DSA:3.40.50.2300 180 337 2.5E-42 T 29-03-2018 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 Pfam PF13377 Periplasmic binding protein-like domain 174 333 3.4E-34 T 29-03-2018 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 1.1E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 SUPERFAMILY SSF53822 63 334 1.14E-82 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 SUPERFAMILY SSF47413 3 62 1.79E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS01535 f7ec3240ab1e252186c595ea3e55e6be 337 Gene3D G3DSA:3.40.50.2300 57 179 2.5E-34 T 29-03-2018 CWR56_RS10330 63bfb82a3b16e865bf9762430d02b530 207 Pfam PF02659 Putative manganese efflux pump 50 203 3.4E-10 T 29-03-2018 IPR003810 Putative manganese efflux pump CWR56_RS10330 63bfb82a3b16e865bf9762430d02b530 207 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 3 206 3.2E-45 T 29-03-2018 IPR014205 Sporulation protein YtaF CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 351 2.1E-142 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 Pfam PF00871 Acetokinase family 5 331 9.5E-59 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 PRINTS PR00471 Acetate kinase family signature 295 311 5.7E-16 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 PRINTS PR00471 Acetate kinase family signature 5 16 5.7E-16 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 PRINTS PR00471 Acetate kinase family signature 179 200 5.7E-16 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 PRINTS PR00471 Acetate kinase family signature 272 285 5.7E-16 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 Gene3D G3DSA:3.30.420.40 2 179 8.6E-52 T 29-03-2018 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 Hamap MF_00542 Probable butyrate kinase [buk]. 1 356 146.533 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 SUPERFAMILY SSF53067 3 173 1.64E-63 T 29-03-2018 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 SUPERFAMILY SSF53067 174 353 1.3E-43 T 29-03-2018 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 Gene3D G3DSA:3.30.420.40 180 349 1.4E-40 T 29-03-2018 CWR56_RS12000 4f2d8f0556ecff7441f9cb6784eb3173 356 PIRSF PIRSF036458 1 354 2.1E-142 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 Gene3D G3DSA:3.40.50.150 159 449 7.7E-72 T 29-03-2018 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 271 277 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 SUPERFAMILY SSF53335 5 486 2.37E-125 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 Pfam PF02384 N-6 DNA Methylase 139 451 2.5E-70 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 161 177 4.8E-17 T 29-03-2018 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 268 280 4.8E-17 T 29-03-2018 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 298 322 4.8E-17 T 29-03-2018 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 185 199 4.8E-17 T 29-03-2018 CWR56_RS15355 4f4f52d921f2821e721db78975cf9e80 487 Pfam PF12161 HsdM N-terminal domain 6 129 2.3E-13 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 340 7.9E-122 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 142 8.9E-33 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 Gene3D G3DSA:3.30.360.10 160 312 5.5E-53 T 29-03-2018 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 315 2.2E-13 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 SMART SM00859 5 142 4.9E-50 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 SUPERFAMILY SSF51735 2 175 8.4E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 SUPERFAMILY SSF55347 150 312 3.6E-48 T 29-03-2018 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 4 338 39.755 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS09720 63272c63f026066b0159f4161aee3dcd 344 Gene3D G3DSA:3.40.50.720 1 159 1.1E-40 T 29-03-2018 CWR56_RS02050 78f2aa1c2ec36db41ee07f9aea660a1e 124 Gene3D G3DSA:3.20.20.440 17 119 3.0E-17 T 29-03-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CWR56_RS02050 78f2aa1c2ec36db41ee07f9aea660a1e 124 SUPERFAMILY SSF51703 15 114 1.49E-13 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CWR56_RS02050 78f2aa1c2ec36db41ee07f9aea660a1e 124 Pfam PF16552 D-ornithine 4,5-aminomutase alpha-subunit 3 117 2.0E-55 T 29-03-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Gene3D G3DSA:3.40.50.1000 521 644 1.9E-17 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Gene3D G3DSA:1.20.1110.10 645 885 4.1E-65 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Pfam PF00689 Cation transporting ATPase, C-terminus 709 877 2.1E-41 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Gene3D G3DSA:2.70.150.10 17 230 2.8E-48 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF81660 335 534 1.0E-54 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 219 358 1.9E-25 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 183 4.3E-20 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 593 715 3.1E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Pfam PF13246 Cation transport ATPase (P-type) 379 464 6.5E-23 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF56784 327 347 8.64E-60 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF56784 478 729 8.64E-60 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Pfam PF00122 E1-E2 ATPase 116 309 3.8E-53 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SMART SM00831 8 81 1.1E-24 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Gene3D G3DSA:3.40.1110.10 293 520 2.6E-53 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF81665 230 323 2.35E-124 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF81665 674 884 2.35E-124 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF81665 7 119 2.35E-124 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 SUPERFAMILY SSF81653 118 228 2.88E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 624 640 2.4E-13 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 656 681 2.4E-13 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 596 612 2.4E-13 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 481 499 2.4E-13 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 544 554 2.7E-40 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 2.7E-40 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 522 533 2.7E-40 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 624 643 2.7E-40 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 660 2.7E-40 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 2.7E-40 T 29-03-2018 CWR56_RS08795 de828bd8bd3c86d32af58d98a43de69d 885 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 76 4.5E-20 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 SMART SM00850 137 228 5.3E-22 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 SUPERFAMILY SSF52172 1 135 6.26E-18 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 Gene3D G3DSA:2.40.50.40 130 197 1.3E-18 T 29-03-2018 CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 SMART SM00448 2 116 9.4E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 Pfam PF04397 LytTr DNA-binding domain 141 227 1.1E-20 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 Gene3D G3DSA:3.40.50.2300 1 129 2.6E-17 T 29-03-2018 CWR56_RS02305 53691cd5f97dc1fe0640d67437ddb590 236 Pfam PF00072 Response regulator receiver domain 4 116 1.9E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.563 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 SUPERFAMILY SSF55257 5 50 3.27E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 SUPERFAMILY SSF55257 172 226 3.27E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 SUPERFAMILY SSF56553 50 171 8.5E-41 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.0E-28 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 SUPERFAMILY SSF47789 247 311 6.93E-25 T 29-03-2018 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 SMART SM00662 20 227 1.7E-94 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 312 2.0E-22 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 1.5E-22 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Gene3D G3DSA:3.30.1360.10 108 224 7.3E-31 T 29-03-2018 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Gene3D G3DSA:3.30.1360.10 1 87 3.2E-19 T 29-03-2018 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 311 2.0E-122 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 7.4E-25 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00230 7859f4e31b2bae8d7439802872c55098 315 Gene3D G3DSA:1.10.150.20 241 315 3.2E-28 T 29-03-2018 CWR56_RS14870 e422720edb91e0024d54f86e943072fa 319 SUPERFAMILY SSF53850 35 315 3.23E-44 T 29-03-2018 CWR56_RS14870 e422720edb91e0024d54f86e943072fa 319 SMART SM00062 34 256 2.0E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS14870 e422720edb91e0024d54f86e943072fa 319 Gene3D G3DSA:3.40.190.10 30 142 8.5E-9 T 29-03-2018 CWR56_RS14870 e422720edb91e0024d54f86e943072fa 319 Gene3D G3DSA:3.40.190.10 143 319 6.2E-35 T 29-03-2018 CWR56_RS14870 e422720edb91e0024d54f86e943072fa 319 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 37 315 2.6E-56 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CWR56_RS14870 e422720edb91e0024d54f86e943072fa 319 Pfam PF09084 NMT1/THI5 like 61 256 5.5E-23 T 29-03-2018 IPR015168 SsuA/THI5-like CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 381 389 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 Gene3D G3DSA:3.20.20.80 1 488 3.3E-143 T 29-03-2018 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 449 461 2.1E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 381 389 2.1E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 424 441 2.1E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 315 329 2.1E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 402 413 2.1E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 Pfam PF00232 Glycosyl hydrolase family 1 3 484 8.6E-119 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR56_RS01850 d4eb5d9b99f277befc5d5fa62585e84b 488 SUPERFAMILY SSF51445 2 481 1.9E-155 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS18025 567d04099fd0e9b6603517355f0639b3 242 Gene3D G3DSA:3.40.50.300 1 229 2.1E-50 T 29-03-2018 CWR56_RS18025 567d04099fd0e9b6603517355f0639b3 242 Pfam PF00005 ABC transporter 22 164 3.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS18025 567d04099fd0e9b6603517355f0639b3 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS18025 567d04099fd0e9b6603517355f0639b3 242 SUPERFAMILY SSF52540 2 225 6.14E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18025 567d04099fd0e9b6603517355f0639b3 242 SMART SM00382 30 213 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS12975 3e911b200697e4ec386fa8315b017693 150 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 3 129 4.2E-36 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS12975 3e911b200697e4ec386fa8315b017693 150 SUPERFAMILY SSF55804 3 146 1.11E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12975 3e911b200697e4ec386fa8315b017693 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 2 145 4.0E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS12975 3e911b200697e4ec386fa8315b017693 150 Gene3D G3DSA:3.40.930.10 1 147 6.6E-33 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Pfam PF13538 UvrD-like helicase C-terminal domain 654 702 5.7E-19 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Pfam PF14490 Helix-hairpin-helix containing domain 139 228 9.8E-32 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Gene3D G3DSA:1.10.8.50 194 224 0.18 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 SUPERFAMILY SSF47781 84 157 4.94E-11 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Pfam PF13604 AAA domain 319 499 5.7E-46 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Gene3D G3DSA:1.10.150.20 87 123 3.4E-10 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 5 724 2.0E-208 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 SMART SM00382 332 450 3.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Gene3D G3DSA:1.10.150.280 124 193 4.3E-8 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 731 27.746 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 SMART SM00278 180 199 170.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 SMART SM00278 116 135 0.69 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Gene3D G3DSA:3.40.50.300 493 715 1.4E-32 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Gene3D G3DSA:3.40.50.300 277 492 3.2E-34 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 Pfam PF14520 Helix-hairpin-helix domain 88 134 3.5E-8 T 29-03-2018 CWR56_RS00630 d1b715edcc14c50f1a13eb6ee9047f22 739 SUPERFAMILY SSF52540 310 707 6.07E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 SUPERFAMILY SSF52540 260 487 2.36E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 Gene3D G3DSA:3.40.50.300 247 492 2.8E-39 T 29-03-2018 CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 SMART SM00382 30 218 1.7E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 SMART SM00382 279 474 0.0014 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 Pfam PF00005 ABC transporter 271 425 2.3E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 Pfam PF00005 ABC transporter 21 170 3.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 SUPERFAMILY SSF52540 4 239 1.36E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 Gene3D G3DSA:3.40.50.300 2 245 1.3E-51 T 29-03-2018 CWR56_RS01550 8c01eed37cc3998a5bbbc8be56bfa611 503 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04130 6d14985033c8685d4cfae83cc9f491ae 411 Gene3D G3DSA:3.40.50.2000 86 402 3.6E-28 T 29-03-2018 CWR56_RS04130 6d14985033c8685d4cfae83cc9f491ae 411 Pfam PF00534 Glycosyl transferases group 1 204 332 1.4E-20 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CWR56_RS04130 6d14985033c8685d4cfae83cc9f491ae 411 Pfam PF13439 Glycosyltransferase Family 4 85 199 1.1E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWR56_RS04130 6d14985033c8685d4cfae83cc9f491ae 411 SUPERFAMILY SSF53756 6 331 9.94E-46 T 29-03-2018 CWR56_RS13630 260db97547c045834885345544770ac8 402 PRINTS PR00173 Glutamate-aspartate symporter signature 277 303 9.3E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS13630 260db97547c045834885345544770ac8 402 PRINTS PR00173 Glutamate-aspartate symporter signature 126 148 9.3E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS13630 260db97547c045834885345544770ac8 402 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 9.3E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS13630 260db97547c045834885345544770ac8 402 PRINTS PR00173 Glutamate-aspartate symporter signature 339 359 9.3E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS13630 260db97547c045834885345544770ac8 402 Pfam PF00375 Sodium:dicarboxylate symporter family 7 386 2.8E-82 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS13630 260db97547c045834885345544770ac8 402 Gene3D G3DSA:1.10.3860.10 1 394 2.3E-67 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS13630 260db97547c045834885345544770ac8 402 SUPERFAMILY SSF118215 7 387 2.48E-79 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS08615 e3ffdf533df9de78514248c54bdef587 219 Gene3D G3DSA:3.30.240.20 79 148 1.4E-25 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CWR56_RS08615 e3ffdf533df9de78514248c54bdef587 219 Pfam PF04239 Protein of unknown function (DUF421) 86 195 1.5E-34 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CWR56_RS08615 e3ffdf533df9de78514248c54bdef587 219 Gene3D G3DSA:3.30.240.20 161 217 1.5E-14 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 8 160 4.2E-58 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 6 162 34.321 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 Pfam PF01467 Cytidylyltransferase-like 9 137 1.1E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 Gene3D G3DSA:3.40.50.620 1 162 2.6E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 SMART SM00764 16 157 9.9E-4 T 29-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 116 138 2.7E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 89 105 2.7E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 24 45 2.7E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 6 24 2.7E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 53 77 2.7E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 2 148 6.0E-4 T 29-03-2018 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 66 2.5E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR56_RS12925 0cd0ea19517af4f1c004d5c332a94ff1 165 SUPERFAMILY SSF52374 5 160 6.44E-44 T 29-03-2018 CWR56_RS15200 15f8ca144e68dc11798b9ea0b6b8e387 102 Gene3D G3DSA:3.40.50.2300 1 102 1.2E-25 T 29-03-2018 CWR56_RS15200 15f8ca144e68dc11798b9ea0b6b8e387 102 SUPERFAMILY SSF52794 1 101 2.88E-24 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15200 15f8ca144e68dc11798b9ea0b6b8e387 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 95 4.5E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS17150 1ebad562bbd67c4cd81936bc68e22fab 290 Gene3D G3DSA:2.70.98.10 2 290 3.9E-53 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CWR56_RS17150 1ebad562bbd67c4cd81936bc68e22fab 290 Pfam PF01263 Aldose 1-epimerase 4 236 1.9E-25 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CWR56_RS17150 1ebad562bbd67c4cd81936bc68e22fab 290 SUPERFAMILY SSF74650 3 288 1.47E-48 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 SUPERFAMILY SSF55031 185 290 4.84E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 SUPERFAMILY SSF53187 6 197 2.78E-74 T 29-03-2018 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 SUPERFAMILY SSF53187 298 389 2.78E-74 T 29-03-2018 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 Pfam PF07687 Peptidase dimerisation domain 185 282 5.8E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 Pfam PF01546 Peptidase family M20/M25/M40 75 374 1.0E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 PIRSF PIRSF005962 1 391 6.1E-117 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 376 1.5E-106 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 Gene3D G3DSA:3.40.630.10 249 390 5.1E-15 T 29-03-2018 CWR56_RS10485 a40739a91f81db5378da406d7d9754db 391 Gene3D G3DSA:3.40.630.10 2 241 1.5E-41 T 29-03-2018 CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 SUPERFAMILY SSF52172 6 128 9.11E-36 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 SUPERFAMILY SSF46894 133 233 1.19E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 SMART SM00862 156 232 1.6E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 Pfam PF00072 Response regulator receiver domain 9 117 7.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 SMART SM00448 7 118 2.5E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 Gene3D G3DSA:3.40.50.2300 6 128 2.7E-30 T 29-03-2018 CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 Gene3D G3DSA:1.10.10.10 129 236 1.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16825 2b75bac73b0f44e4d4c348ac4d4bb27f 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 7.7E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS07160 33416676e5c792fe8bc49ce5ea996ee5 307 Pfam PF10728 Domain of unknown function (DUF2520) 127 252 8.3E-31 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 CWR56_RS07160 33416676e5c792fe8bc49ce5ea996ee5 307 SUPERFAMILY SSF51735 1 158 6.72E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS07160 33416676e5c792fe8bc49ce5ea996ee5 307 SUPERFAMILY SSF48179 163 258 2.28E-21 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS07160 33416676e5c792fe8bc49ce5ea996ee5 307 Gene3D G3DSA:1.10.1040.20 162 258 3.4E-20 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 CWR56_RS07160 33416676e5c792fe8bc49ce5ea996ee5 307 Gene3D G3DSA:3.40.50.720 1 159 4.4E-9 T 29-03-2018 CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 Gene3D G3DSA:3.30.450.90 46 181 2.4E-41 T 29-03-2018 CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 276 290 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 SMART SM00382 209 332 0.0015 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 Pfam PF00437 Type II/IV secretion system protein 84 348 6.6E-74 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 SUPERFAMILY SSF160246 4 67 2.59E-7 T 29-03-2018 CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 Gene3D G3DSA:3.40.50.300 187 448 6.1E-57 T 29-03-2018 CWR56_RS16575 6271a99e37c554024c7cdda7a8a4d0bc 449 SUPERFAMILY SSF52540 61 443 3.34E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Pfam PF02436 Conserved carboxylase domain 826 1025 1.9E-71 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:3.30.470.20 214 455 3.6E-92 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 157 171 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SUPERFAMILY SSF52440 3 117 1.08E-43 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Pfam PF00682 HMGL-like 532 795 4.9E-27 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SUPERFAMILY SSF56059 87 330 1.56E-68 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:3.20.20.70 528 827 3.7E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:3.10.600.10 989 1059 5.7E-21 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Pfam PF00289 Biotin carboxylase, N-terminal domain 5 114 1.1E-41 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SUPERFAMILY SSF51230 1066 1142 5.5E-19 T 29-03-2018 IPR011053 Single hybrid motif CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SUPERFAMILY SSF89000 831 1007 1.02E-53 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Pfam PF00364 Biotin-requiring enzyme 1077 1142 6.4E-15 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:3.40.50.20 4 127 7.2E-51 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1099 1116 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 7 1142 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 PIRSF PIRSF001594 1 1143 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SUPERFAMILY SSF51569 524 816 1.74E-81 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:1.10.10.60 942 988 1.2E-16 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 119 326 7.3E-78 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:2.40.50.100 1072 1143 3.0E-16 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:3.10.600.10 465 527 2.4E-7 T 29-03-2018 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Pfam PF02785 Biotin carboxylase C-terminal domain 346 454 3.4E-30 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SMART SM00878 346 453 2.6E-45 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 Gene3D G3DSA:3.30.1490.20 128 213 1.1E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS18830 a598eb32f22114bd95147e20675a8ec1 1143 SUPERFAMILY SSF51246 341 459 9.94E-35 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 SUPERFAMILY SSF51735 101 253 4.04E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 Gene3D G3DSA:3.40.50.10860 2 112 7.2E-35 T 29-03-2018 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 2.5E-26 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 267 29.475 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 Gene3D G3DSA:3.40.50.720 113 220 3.2E-15 T 29-03-2018 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 SUPERFAMILY SSF53223 3 100 2.01E-28 T 29-03-2018 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 Gene3D G3DSA:3.40.50.10860 221 269 3.2E-5 T 29-03-2018 CWR56_RS08865 dcab92cfbc1f5f4e93695ff614b857e7 269 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 254 1.1E-62 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Pfam PF16326 ABC transporter C-terminal domain 564 629 2.6E-18 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Pfam PF12848 ABC transporter 225 292 2.0E-12 T 29-03-2018 IPR032781 ABC-transporter extension domain CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 SUPERFAMILY SSF52540 4 239 3.39E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 SMART SM00382 28 231 6.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 SMART SM00382 342 512 3.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Gene3D G3DSA:3.40.50.300 4 283 1.1E-56 T 29-03-2018 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Gene3D G3DSA:3.90.20.10 560 639 0.01 T 29-03-2018 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 SUPERFAMILY SSF52540 311 521 3.4E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Pfam PF00005 ABC transporter 334 468 1.9E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Pfam PF00005 ABC transporter 19 186 5.4E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 Gene3D G3DSA:3.40.50.300 284 550 1.1E-48 T 29-03-2018 CWR56_RS06575 48a963934118e1fb232395b082db33f0 639 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 Gene3D G3DSA:3.40.50.2300 1 127 2.8E-35 T 29-03-2018 CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 SUPERFAMILY SSF46894 130 224 1.16E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 Gene3D G3DSA:1.10.10.10 128 228 4.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 1.9E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 SMART SM00448 2 112 3.3E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 SMART SM00862 147 224 1.0E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 SUPERFAMILY SSF52172 2 129 3.56E-38 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS00780 8cddbb3d21f7da70d4deedc144e0ed4b 228 Pfam PF00072 Response regulator receiver domain 4 113 4.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13785 d0cd15fc262434a8f61f3a69ecb5c47f 312 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 87 311 1.1E-91 T 29-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA CWR56_RS13785 d0cd15fc262434a8f61f3a69ecb5c47f 312 SUPERFAMILY SSF88713 112 307 6.67E-56 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS13785 d0cd15fc262434a8f61f3a69ecb5c47f 312 Gene3D G3DSA:3.20.20.370 84 311 2.3E-50 T 29-03-2018 CWR56_RS13785 d0cd15fc262434a8f61f3a69ecb5c47f 312 Pfam PF01522 Polysaccharide deacetylase 122 245 4.7E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 Hamap MF_00158 Pantothenate synthetase [panC]. 1 278 38.362 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 3 277 1.6E-103 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 SUPERFAMILY SSF52374 3 279 3.75E-106 T 29-03-2018 CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 Pfam PF02569 Pantoate-beta-alanine ligase 3 276 3.3E-104 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 Gene3D G3DSA:3.40.50.620 1 173 2.1E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 Gene3D G3DSA:3.30.1300.10 174 282 6.0E-31 T 29-03-2018 CWR56_RS07150 3e65f6f8debd8b641ed5551df6b2eeef 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 70 6.9E-9 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 SUPERFAMILY SSF46785 1 84 1.34E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 Pfam PF01037 Lrp/AsnC ligand binding domain 71 139 9.3E-19 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 1.9E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 Gene3D G3DSA:1.10.10.10 1 52 6.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.3E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.3E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.3E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 Gene3D G3DSA:3.30.70.920 54 145 8.8E-24 T 29-03-2018 CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 SUPERFAMILY SSF54909 63 143 1.61E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CWR56_RS16815 76620f2bd5f1691d3addc6e2cf006391 151 SMART SM00344 1 108 4.6E-34 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CWR56_RS06480 35ea245598fbbf3168d43b5062d32daa 328 SUPERFAMILY SSF50891 179 293 1.59E-6 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS06480 35ea245598fbbf3168d43b5062d32daa 328 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 287 1.1E-89 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR56_RS06480 35ea245598fbbf3168d43b5062d32daa 328 SMART SM00797 24 304 2.2E-138 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR56_RS06480 35ea245598fbbf3168d43b5062d32daa 328 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 9 312 3.9E-95 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR56_RS06920 226777ceea9c7f00afcef2551c298991 99 Pfam PF00581 Rhodanese-like domain 8 97 2.6E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06920 226777ceea9c7f00afcef2551c298991 99 SUPERFAMILY SSF52821 3 98 7.2E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06920 226777ceea9c7f00afcef2551c298991 99 Gene3D G3DSA:3.40.250.10 2 99 1.2E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS06920 226777ceea9c7f00afcef2551c298991 99 SMART SM00450 6 99 1.6E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS16845 5ab48d8d750226a40ac05ee29ebce0cd 331 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16845 5ab48d8d750226a40ac05ee29ebce0cd 331 Gene3D G3DSA:3.40.50.300 1 293 5.4E-55 T 29-03-2018 CWR56_RS16845 5ab48d8d750226a40ac05ee29ebce0cd 331 SMART SM00382 49 234 3.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16845 5ab48d8d750226a40ac05ee29ebce0cd 331 Pfam PF00005 ABC transporter 43 184 1.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16845 5ab48d8d750226a40ac05ee29ebce0cd 331 SUPERFAMILY SSF52540 32 255 1.84E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 SMART SM00387 267 378 1.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 365 1.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 SUPERFAMILY SSF55874 211 376 8.38E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 SMART SM00388 155 222 1.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 218 5.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 Gene3D G3DSA:3.30.565.10 226 379 8.1E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 SUPERFAMILY SSF47384 141 220 2.94E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 Gene3D G3DSA:1.10.287.130 146 218 4.2E-13 T 29-03-2018 CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 3.1E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07725 a61cfa91e37fe62ba4ef9c2ed262776e 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 3.1E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 SMART SM01061 1 60 2.1E-26 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 SUPERFAMILY SSF63520 59 165 3.53E-29 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 Pfam PF03123 CAT RNA binding domain 1 55 1.2E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 SUPERFAMILY SSF50151 1 55 5.75E-16 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 Gene3D G3DSA:1.10.1790.10 57 165 3.5E-28 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 Gene3D G3DSA:1.10.1790.10 166 278 5.3E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 SUPERFAMILY SSF63520 175 274 2.35E-26 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 Pfam PF00874 PRD domain 77 163 1.4E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 Pfam PF00874 PRD domain 181 273 7.1E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS13495 bfc4f35f6bf8471d23281ba41bf284d9 280 Gene3D G3DSA:2.30.24.10 1 56 7.8E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 Gene3D G3DSA:2.170.190.11 45 134 2.6E-18 T 29-03-2018 CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 Pfam PF00994 Probable molybdopterin binding domain 173 310 5.6E-24 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 Gene3D G3DSA:3.40.980.10 143 320 4.4E-42 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 SUPERFAMILY SSF53218 170 313 1.11E-34 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 SUPERFAMILY SSF63882 1 168 1.57E-47 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 SMART SM00852 173 312 3.4E-30 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 170 307 3.2E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS05000 9c5aca5220157e9390d4b5cd80923e74 393 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 160 1.3E-34 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 455 591 3.7E-22 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 SUPERFAMILY SSF52794 358 436 1.26E-10 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Pfam PF08279 HTH domain 8 64 6.2E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 SUPERFAMILY SSF63520 252 348 1.19E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Gene3D G3DSA:3.40.50.2300 357 443 8.5E-20 T 29-03-2018 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Gene3D G3DSA:1.10.10.10 79 148 2.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Gene3D G3DSA:1.10.10.10 1 68 1.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 SUPERFAMILY SSF55804 452 591 2.09E-24 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 363 435 2.8E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Pfam PF00874 PRD domain 260 347 4.3E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Gene3D G3DSA:3.40.930.10 444 592 1.4E-24 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Pfam PF05043 Mga helix-turn-helix domain 99 142 5.5E-7 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS11250 d9bce84b9f3c000285c398528a1e107a 592 Gene3D G3DSA:1.10.1790.10 242 351 8.8E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 SMART SM01061 1 58 1.0E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 SUPERFAMILY SSF63520 170 272 1.83E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 SUPERFAMILY SSF50151 2 54 5.23E-15 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 SUPERFAMILY SSF63520 54 166 2.09E-28 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 Gene3D G3DSA:1.10.1790.10 53 164 3.8E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 Gene3D G3DSA:1.10.1790.10 165 276 1.8E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 Gene3D G3DSA:2.30.24.10 1 52 1.1E-17 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 Pfam PF03123 CAT RNA binding domain 2 55 2.5E-18 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 Pfam PF00874 PRD domain 179 271 5.0E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15110 cf06ab629ca9a1e659366939b6ddffc0 278 Pfam PF00874 PRD domain 74 160 6.8E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 Pfam PF00202 Aminotransferase class-III 30 422 1.6E-109 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 SUPERFAMILY SSF53383 23 423 1.27E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 PIRSF PIRSF000521 129 425 1.1E-32 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 PIRSF PIRSF000521 7 135 0.0015 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 Gene3D G3DSA:3.90.1150.10 309 437 1.6E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 Gene3D G3DSA:3.40.640.10 188 308 4.3E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS10400 8616a76d6bda7b4187a5b8bf8e457840 441 Gene3D G3DSA:3.90.1150.10 3 187 5.2E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 PIRSF PIRSF004640 1 351 5.1E-151 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 Pfam PF04551 GcpE protein 8 350 6.1E-145 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 SUPERFAMILY SSF56014 262 329 9.53E-11 T 29-03-2018 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 SUPERFAMILY SSF51717 13 204 1.18E-11 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 5 348 2.0E-132 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 3 350 34.66 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CWR56_RS10245 77f5cd035097f115719d80c486de261e 351 Gene3D G3DSA:3.20.20.120 13 203 1.3E-26 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 SUPERFAMILY SSF53335 76 450 9.28E-85 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 Gene3D G3DSA:3.40.50.150 75 450 1.9E-56 T 29-03-2018 CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 382 413 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 Gene3D G3DSA:2.40.50.140 1 74 2.3E-18 T 29-03-2018 CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 SUPERFAMILY SSF50249 7 65 7.43E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 88 445 2.2E-25 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 434 444 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 444 8.4E-149 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CWR56_RS16890 55c9781bea9071cab9f5d1cd973d3fbe 452 Pfam PF01938 TRAM domain 10 58 1.2E-6 T 29-03-2018 IPR002792 TRAM domain CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 SMART SM00028 270 303 5.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 SMART SM00028 198 231 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 SMART SM00028 666 699 2.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 Pfam PF00535 Glycosyl transferase family 2 4 90 2.3E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 Gene3D G3DSA:1.25.40.10 174 639 1.7E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 Gene3D G3DSA:1.25.40.10 640 713 4.8E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 SUPERFAMILY SSF53448 1 101 1.18E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 Gene3D G3DSA:3.90.550.10 2 173 7.5E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01210 324c4109b5adc1d198d10035d4bdd030 713 SUPERFAMILY SSF48452 186 304 3.08E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS07535 5624953237241f9e2800710a9a931ed2 320 Pfam PF13407 Periplasmic binding protein domain 39 296 2.0E-50 T 29-03-2018 IPR025997 Periplasmic binding protein CWR56_RS07535 5624953237241f9e2800710a9a931ed2 320 Gene3D G3DSA:3.40.50.2300 33 165 2.8E-22 T 29-03-2018 CWR56_RS07535 5624953237241f9e2800710a9a931ed2 320 Gene3D G3DSA:3.40.50.2300 166 318 1.9E-29 T 29-03-2018 CWR56_RS07535 5624953237241f9e2800710a9a931ed2 320 SUPERFAMILY SSF53822 35 316 6.04E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS14880 18dda15dc7e35458ad3c1b00f11680fd 260 SUPERFAMILY SSF161098 57 242 5.23E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS14880 18dda15dc7e35458ad3c1b00f11680fd 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 251 4.2E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS14880 18dda15dc7e35458ad3c1b00f11680fd 260 Gene3D G3DSA:1.10.3720.10 9 256 4.1E-26 T 29-03-2018 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 SUPERFAMILY SSF88659 167 255 1.78E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 Gene3D G3DSA:1.10.1270.10 165 257 1.8E-15 T 29-03-2018 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 Gene3D G3DSA:1.10.10.10 103 156 4.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 Pfam PF04545 Sigma-70, region 4 203 251 4.0E-12 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 SUPERFAMILY SSF88659 107 184 2.62E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 Gene3D G3DSA:1.10.601.10 12 102 7.6E-22 T 29-03-2018 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 SUPERFAMILY SSF88946 12 104 1.83E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 252 1.4E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 Pfam PF04539 Sigma-70 region 3 113 181 4.0E-12 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 253 1.4E-76 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 PRINTS PR00046 Major sigma-70 factor signature 223 238 4.7E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 PRINTS PR00046 Major sigma-70 factor signature 238 249 4.7E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 PRINTS PR00046 Major sigma-70 factor signature 206 218 4.7E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 PRINTS PR00046 Major sigma-70 factor signature 58 71 4.7E-5 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS18490 abf2cf325aba0ab78fd71bba354ec4b8 257 Pfam PF04542 Sigma-70 region 2 34 103 7.7E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 SUPERFAMILY SSF53187 322 406 6.57E-79 T 29-03-2018 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 SUPERFAMILY SSF53187 3 211 6.57E-79 T 29-03-2018 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 SUPERFAMILY SSF55031 210 320 1.79E-40 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 Pfam PF07687 Peptidase dimerisation domain 208 309 6.6E-12 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 Gene3D G3DSA:3.40.630.10 1 408 3.5E-53 T 29-03-2018 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 Pfam PF01546 Peptidase family M20/M25/M40 140 402 5.6E-15 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 139 178 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 407 3.2E-162 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 PIRSF PIRSF037215 1 408 9.4E-179 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWR56_RS04800 1fa6ece0bcb98cd440b4d43449498422 408 Hamap MF_00550 Peptidase T [pepT]. 2 404 54.663 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWR56_RS18905 a2ffb4029b471e41a686907fe6398080 322 SUPERFAMILY SSF52518 4 322 1.11E-97 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS18905 a2ffb4029b471e41a686907fe6398080 322 Pfam PF00676 Dehydrogenase E1 component 16 312 1.1E-84 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CWR56_RS18905 a2ffb4029b471e41a686907fe6398080 322 Gene3D G3DSA:3.40.50.970 2 322 1.2E-85 T 29-03-2018 CWR56_RS15045 0eed10192ef688405384067942c51a30 284 Gene3D G3DSA:1.20.1250.20 88 266 1.4E-5 T 29-03-2018 CWR56_RS15045 0eed10192ef688405384067942c51a30 284 SUPERFAMILY SSF103481 202 280 7.19E-6 T 29-03-2018 CWR56_RS15045 0eed10192ef688405384067942c51a30 284 Pfam PF06800 Sugar transport protein 5 283 9.2E-85 T 29-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CWR56_RS15045 0eed10192ef688405384067942c51a30 284 SUPERFAMILY SSF103481 38 138 1.31E-9 T 29-03-2018 CWR56_RS14360 e1dca96524719099d32d4df8014122aa 320 Pfam PF00892 EamA-like transporter family 3 138 9.9E-24 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS14360 e1dca96524719099d32d4df8014122aa 320 Pfam PF00892 EamA-like transporter family 148 300 2.7E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS14360 e1dca96524719099d32d4df8014122aa 320 SUPERFAMILY SSF103481 225 303 3.66E-10 T 29-03-2018 CWR56_RS14360 e1dca96524719099d32d4df8014122aa 320 SUPERFAMILY SSF103481 38 138 1.7E-14 T 29-03-2018 CWR56_RS17065 6b32e6f279b5b71f67af345f33cb2748 373 SUPERFAMILY SSF159664 245 372 1.29E-36 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CWR56_RS17065 6b32e6f279b5b71f67af345f33cb2748 373 SUPERFAMILY SSF159672 5 189 2.09E-58 T 29-03-2018 CWR56_RS17065 6b32e6f279b5b71f67af345f33cb2748 373 SUPERFAMILY SSF159672 227 259 2.09E-58 T 29-03-2018 CWR56_RS17065 6b32e6f279b5b71f67af345f33cb2748 373 Pfam PF11760 Cobalamin synthesis G N-terminal 59 139 2.9E-34 T 29-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CWR56_RS17065 6b32e6f279b5b71f67af345f33cb2748 373 Gene3D G3DSA:3.30.420.180 242 373 1.4E-32 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CWR56_RS17065 6b32e6f279b5b71f67af345f33cb2748 373 Pfam PF01890 Cobalamin synthesis G C-terminus 252 368 5.9E-31 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CWR56_RS13465 c7a0e76b1f6ddfd10fd879d6cba8c229 421 Gene3D G3DSA:3.30.830.10 6 220 6.3E-22 T 29-03-2018 CWR56_RS13465 c7a0e76b1f6ddfd10fd879d6cba8c229 421 Gene3D G3DSA:3.30.830.10 221 412 2.8E-29 T 29-03-2018 CWR56_RS13465 c7a0e76b1f6ddfd10fd879d6cba8c229 421 Pfam PF05193 Peptidase M16 inactive domain 182 358 1.0E-21 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CWR56_RS13465 c7a0e76b1f6ddfd10fd879d6cba8c229 421 SUPERFAMILY SSF63411 7 228 1.04E-20 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS13465 c7a0e76b1f6ddfd10fd879d6cba8c229 421 SUPERFAMILY SSF63411 250 412 1.83E-27 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 SUPERFAMILY SSF52540 30 220 2.87E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 SMART SM00382 36 178 8.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 SUPERFAMILY SSF48019 243 359 7.91E-21 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 Pfam PF13177 DNA polymerase III, delta subunit 19 177 3.8E-45 T 29-03-2018 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 357 2.5E-144 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 362 8.4E-17 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 Gene3D G3DSA:1.20.272.10 242 362 3.4E-21 T 29-03-2018 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 Gene3D G3DSA:1.10.8.60 166 241 2.0E-23 T 29-03-2018 CWR56_RS18570 9372ad58cd25bf2032aee07584024db5 545 Gene3D G3DSA:3.40.50.300 1 165 4.6E-41 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Gene3D G3DSA:1.10.8.60 498 583 1.9E-34 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Gene3D G3DSA:2.30.130.40 1 119 1.3E-26 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Gene3D G3DSA:1.10.4060.10 126 217 8.3E-23 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 TIGRFAM TIGR00763 lon: endopeptidase La 13 778 3.1E-298 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Gene3D G3DSA:3.30.230.10 584 787 1.2E-68 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 SUPERFAMILY SSF88697 11 206 2.49E-39 T 29-03-2018 IPR015947 PUA-like domain CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 PIRSF PIRSF001174 1 782 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 SUPERFAMILY SSF52540 309 582 1.27E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 577 779 2.5E-90 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 358 495 4.2E-23 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Gene3D G3DSA:3.40.50.300 319 497 4.5E-33 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 710 729 1.2E-48 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 362 381 1.2E-48 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 680 699 1.2E-48 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 733 751 1.2E-48 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 602 618 1.2E-48 T 29-03-2018 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 SUPERFAMILY SSF54211 602 777 7.21E-58 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 683 691 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 SMART SM00382 354 499 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 SMART SM00464 11 208 7.8E-62 T 29-03-2018 IPR003111 Lon, substrate-binding domain CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Hamap MF_01973 Lon protease [lon]. 12 779 71.643 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CWR56_RS16600 b9d83a63fcab8ed60fc12710a47aa85b 787 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 206 7.6E-41 T 29-03-2018 IPR003111 Lon, substrate-binding domain CWR56_RS09875 fed2ea458c14ffe8c62734d631df0a39 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 291 8.0E-58 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CWR56_RS09875 fed2ea458c14ffe8c62734d631df0a39 299 Gene3D G3DSA:3.40.50.10330 1 130 2.1E-27 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWR56_RS09875 fed2ea458c14ffe8c62734d631df0a39 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 126 4.1E-28 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWR56_RS09875 fed2ea458c14ffe8c62734d631df0a39 299 SUPERFAMILY SSF111331 1 292 1.42E-67 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWR56_RS09875 fed2ea458c14ffe8c62734d631df0a39 299 SMART SM00046 3 130 5.0E-8 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 PIRSF PIRSF001467 2 164 1.7E-41 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 SUPERFAMILY SSF50891 6 162 1.46E-55 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 Gene3D G3DSA:2.40.100.10 1 173 2.0E-62 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 8 160 3.9E-52 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 121 136 1.3E-20 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 93 108 1.3E-20 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 108 120 1.3E-20 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 22 37 1.3E-20 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR56_RS01730 201b05352658a555d3fd8f1cf25fc71f 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 48 60 1.3E-20 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR56_RS06820 b0b08c31d1c4b80ee23c2b8382a58bfc 267 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 48 61 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS06820 b0b08c31d1c4b80ee23c2b8382a58bfc 267 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 14 263 6.1E-98 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CWR56_RS06820 b0b08c31d1c4b80ee23c2b8382a58bfc 267 Pfam PF00809 Pterin binding enzyme 15 249 4.5E-88 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS06820 b0b08c31d1c4b80ee23c2b8382a58bfc 267 Gene3D G3DSA:3.20.20.20 4 267 1.9E-107 T 29-03-2018 CWR56_RS06820 b0b08c31d1c4b80ee23c2b8382a58bfc 267 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 14 29 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS06820 b0b08c31d1c4b80ee23c2b8382a58bfc 267 SUPERFAMILY SSF51717 6 266 1.57E-99 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS14965 1da6c05fac875a39ec175091a191a707 300 Gene3D G3DSA:3.90.850.10 49 300 2.2E-67 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR56_RS14965 1da6c05fac875a39ec175091a191a707 300 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 89 299 1.4E-61 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR56_RS14965 1da6c05fac875a39ec175091a191a707 300 SUPERFAMILY SSF56529 84 299 1.11E-67 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR56_RS01700 21577d781d12be419e33fd8e4d917871 92 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 92 45.465 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CWR56_RS01700 21577d781d12be419e33fd8e4d917871 92 Pfam PF02553 Cobalt transport protein component CbiN 8 74 3.0E-29 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CWR56_RS01700 21577d781d12be419e33fd8e4d917871 92 TIGRFAM TIGR01165 cbiN: cobalt transport protein 5 89 1.6E-34 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CWR56_RS08315 2846ffba7f67ea5aa18618d6a73ae22c 206 SUPERFAMILY SSF56507 20 188 6.54E-11 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS08315 2846ffba7f67ea5aa18618d6a73ae22c 206 Gene3D G3DSA:3.10.196.10 78 205 4.7E-5 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17645 ec486f43b05bd939104045e67547521b 256 PIRSF PIRSF005902 1 256 4.7E-89 T 29-03-2018 IPR001130 TatD family GO:0016788 CWR56_RS17645 ec486f43b05bd939104045e67547521b 256 Gene3D G3DSA:3.20.20.140 1 256 9.8E-94 T 29-03-2018 CWR56_RS17645 ec486f43b05bd939104045e67547521b 256 SUPERFAMILY SSF51556 2 255 1.88E-94 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS17645 ec486f43b05bd939104045e67547521b 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CWR56_RS17645 ec486f43b05bd939104045e67547521b 256 Pfam PF01026 TatD related DNase 3 254 1.4E-84 T 29-03-2018 IPR001130 TatD family GO:0016788 CWR56_RS17645 ec486f43b05bd939104045e67547521b 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 1.2E-92 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 Gene3D G3DSA:3.60.21.10 25 344 5.2E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 PRINTS PR01607 Apyrase family signature 297 317 8.8E-12 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 PRINTS PR01607 Apyrase family signature 265 288 8.8E-12 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 PRINTS PR01607 Apyrase family signature 27 45 8.8E-12 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 PRINTS PR01607 Apyrase family signature 237 254 8.8E-12 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 SUPERFAMILY SSF56300 363 633 9.22E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 Pfam PF00149 Calcineurin-like phosphoesterase 30 282 6.1E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 Pfam PF00149 Calcineurin-like phosphoesterase 370 580 1.2E-6 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 Gene3D G3DSA:3.60.21.10 352 634 1.2E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 SUPERFAMILY SSF56300 25 334 1.28E-51 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03310 6578c03f29782ed7cfeb4f9ddfa99f91 634 ProSitePatterns PS00785 5'-nucleotidase signature 1. 29 41 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 Gene3D G3DSA:3.40.50.2300 181 277 1.8E-38 T 29-03-2018 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 184 274 5.6E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 133 5.4E-39 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 184 265 1.2E-31 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 294 632 5.1E-124 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 SUPERFAMILY SSF52794 181 283 2.62E-37 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 Gene3D G3DSA:3.40.930.10 1 150 4.9E-44 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 148 2.0E-38 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 Pfam PF02378 Phosphotransferase system, EIIC 310 579 8.2E-18 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS11240 160a5a1673b9b6236a11793082230ca5 639 SUPERFAMILY SSF55804 1 148 4.19E-42 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 Gene3D G3DSA:1.10.10.10 10 134 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 SMART SM00347 30 130 2.1E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 SUPERFAMILY SSF46785 23 145 1.43E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 Pfam PF01047 MarR family 38 94 2.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 4.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 4.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 4.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS06215 ec51820cd4a3dc35b95b123f4a4d07ab 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 4.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS09680 dde57b4db9d3025275f6f0a39791b281 137 SUPERFAMILY SSF55729 34 137 1.16E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS09680 dde57b4db9d3025275f6f0a39791b281 137 Pfam PF00583 Acetyltransferase (GNAT) family 32 115 2.8E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS09680 dde57b4db9d3025275f6f0a39791b281 137 Gene3D G3DSA:3.40.630.30 6 137 2.3E-17 T 29-03-2018 CWR56_RS08155 ea63c09f507882e831f52df77628ba5c 256 SUPERFAMILY SSF110399 2 235 4.32E-80 T 29-03-2018 CWR56_RS08155 ea63c09f507882e831f52df77628ba5c 256 Gene3D G3DSA:3.20.20.70 1 256 2.0E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS08155 ea63c09f507882e831f52df77628ba5c 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 248 7.7E-108 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CWR56_RS08155 ea63c09f507882e831f52df77628ba5c 256 Hamap MF_00443 Thiazole synthase [thiG]. 3 254 40.15 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Gene3D G3DSA:3.30.1330.10 631 819 5.2E-22 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SUPERFAMILY SSF52317 1002 1267 2.78E-71 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SUPERFAMILY SSF55326 647 827 1.44E-40 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 12 1267 0.0 T 29-03-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Pfam PF02769 AIR synthase related protein, C-terminal domain 448 597 8.3E-21 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Gene3D G3DSA:3.30.1280.10 12 80 0.012 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Gene3D G3DSA:3.90.650.10 443 616 1.4E-19 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Gene3D G3DSA:3.90.650.10 820 975 1.1E-8 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1005 1267 4.8E-93 T 29-03-2018 CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Gene3D G3DSA:3.30.1330.10 213 442 3.1E-44 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 Gene3D G3DSA:3.40.50.880 1003 1268 1.4E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SMART SM01211 1004 1267 1.2E-117 T 29-03-2018 CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SUPERFAMILY SSF56042 445 672 3.66E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SUPERFAMILY SSF55326 310 438 1.05E-29 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SUPERFAMILY SSF55326 213 239 1.05E-29 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01115 d393cf0adda9d6280a285249035d2575 1268 SUPERFAMILY SSF56042 828 990 7.06E-17 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 147 3.0E-77 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 SUPERFAMILY SSF63411 1 147 2.38E-58 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 PIRSF PIRSF006160 1 150 1.1E-60 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 Gene3D G3DSA:3.30.1360.80 1 142 2.7E-54 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 7.8E-35 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 7.8E-35 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 7.8E-35 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 73 91 7.8E-35 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 7.8E-35 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 148 34.622 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS17970 80da98293ec15688d69033463b0efee7 151 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 144 5.8E-50 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS08210 cf5a848cd90daafa48e5803f82dc7130 143 SUPERFAMILY SSF50800 1 142 1.57E-35 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CWR56_RS08210 cf5a848cd90daafa48e5803f82dc7130 143 Gene3D G3DSA:2.40.33.20 1 143 1.5E-23 T 29-03-2018 CWR56_RS02275 3dfed1101d022e4f965b760cf6d3dff5 157 Gene3D G3DSA:3.40.35.10 3 157 7.3E-51 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS02275 3dfed1101d022e4f965b760cf6d3dff5 157 Pfam PF03830 PTS system sorbose subfamily IIB component 4 150 1.9E-48 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS02275 3dfed1101d022e4f965b760cf6d3dff5 157 SUPERFAMILY SSF52728 3 154 4.05E-45 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 SUPERFAMILY SSF51735 1 336 1.59E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 1.7E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 1.7E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 1.7E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 5.8E-142 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 Gene3D G3DSA:3.40.50.720 1 206 4.6E-36 T 29-03-2018 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 1.8E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 Gene3D G3DSA:3.90.25.10 207 252 1.6E-8 T 29-03-2018 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 Gene3D G3DSA:3.90.25.10 253 314 3.7E-23 T 29-03-2018 CWR56_RS13735 77d48bd2a09da791554cecd83b576d8c 337 Gene3D G3DSA:3.90.25.10 315 336 6.6E-4 T 29-03-2018 CWR56_RS06120 e63290ba21778fd770eab1f875cc9731 281 Gene3D G3DSA:2.20.28.50 28 52 8.4E-14 T 29-03-2018 CWR56_RS06120 e63290ba21778fd770eab1f875cc9731 281 Gene3D G3DSA:3.30.1180.10 154 281 5.6E-26 T 29-03-2018 CWR56_RS06120 e63290ba21778fd770eab1f875cc9731 281 Gene3D G3DSA:3.40.50.10440 53 151 6.3E-33 T 29-03-2018 CWR56_RS06120 e63290ba21778fd770eab1f875cc9731 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 3.4E-85 T 29-03-2018 IPR003797 DegV CWR56_RS06120 e63290ba21778fd770eab1f875cc9731 281 SUPERFAMILY SSF82549 1 278 3.92E-73 T 29-03-2018 CWR56_RS06120 e63290ba21778fd770eab1f875cc9731 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 3.8E-75 T 29-03-2018 IPR003797 DegV CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 SUPERFAMILY SSF52151 189 307 1.78E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 SUPERFAMILY SSF52151 4 122 1.78E-67 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 Gene3D G3DSA:3.40.366.10 3 141 4.6E-39 T 29-03-2018 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 Gene3D G3DSA:3.30.70.250 142 184 1.0E-22 T 29-03-2018 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 Gene3D G3DSA:3.40.366.10 185 310 6.3E-22 T 29-03-2018 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 PIRSF PIRSF000446 1 309 2.8E-100 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 SUPERFAMILY SSF55048 130 196 7.59E-17 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 3.1E-25 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 288 5.6E-101 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CWR56_RS05380 7350b08e7016c20f58ac785296137fe7 316 Pfam PF00698 Acyl transferase domain 7 288 2.3E-36 T 29-03-2018 IPR014043 Acyl transferase CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 PIRSF PIRSF001338 1 158 3.3E-62 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 Gene3D G3DSA:3.40.50.7700 1 158 6.6E-58 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 Pfam PF00731 AIR carboxylase 2 147 1.1E-55 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 SUPERFAMILY SSF52255 1 157 4.58E-56 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 153 28.196 T 29-03-2018 IPR033747 Class I PurE CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 156 1.5E-54 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS01080 b402f82de585fd0e53724d2cbaf507a8 158 SMART SM01001 1 149 1.7E-76 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 4.2E-26 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 SUPERFAMILY SSF55653 57 147 3.92E-25 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 SUPERFAMILY SSF55658 1 56 1.29E-16 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 Gene3D G3DSA:3.10.430.100 63 147 8.3E-28 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.3E-42 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.457 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 6.7E-23 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18315 a767a739a85b3e9fdf6cf0af88fbd664 149 Gene3D G3DSA:3.40.5.10 1 49 2.8E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Pfam PF13237 4Fe-4S dicluster domain 366 418 4.4E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 128 273 3.8E-51 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 SUPERFAMILY SSF46548 326 438 1.08E-17 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Gene3D G3DSA:3.30.70.20 360 407 1.7E-7 T 29-03-2018 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 102 2.9E-39 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 445 153.876 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 407 418 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Pfam PF10531 SLBB domain 287 337 5.6E-12 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 Gene3D G3DSA:3.30.70.20 408 433 0.24 T 29-03-2018 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 SUPERFAMILY SSF142019 89 292 1.96E-57 T 29-03-2018 CWR56_RS05155 79976d4df2c14aeacb91849b54361e05 445 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 3 437 5.2E-168 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 CWR56_RS11625 9015ceadf19c73ba6e3c4e2bb24643be 435 SUPERFAMILY SSF100950 3 222 2.23E-55 T 29-03-2018 CWR56_RS11625 9015ceadf19c73ba6e3c4e2bb24643be 435 Gene3D G3DSA:3.40.1080.10 191 429 3.8E-67 T 29-03-2018 CWR56_RS11625 9015ceadf19c73ba6e3c4e2bb24643be 435 SUPERFAMILY SSF100950 188 431 1.57E-67 T 29-03-2018 CWR56_RS11625 9015ceadf19c73ba6e3c4e2bb24643be 435 Gene3D G3DSA:3.40.1080.10 6 183 3.8E-46 T 29-03-2018 CWR56_RS11625 9015ceadf19c73ba6e3c4e2bb24643be 435 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 4 179 5.4E-21 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CWR56_RS11625 9015ceadf19c73ba6e3c4e2bb24643be 435 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 271 425 6.8E-63 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CWR56_RS15820 20531feee7b0ee0d5d9b6f51c05403e7 388 SUPERFAMILY SSF56349 68 380 1.88E-66 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS15820 20531feee7b0ee0d5d9b6f51c05403e7 388 Gene3D G3DSA:1.10.150.130 62 175 2.6E-17 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS15820 20531feee7b0ee0d5d9b6f51c05403e7 388 Gene3D G3DSA:1.10.443.10 176 385 3.0E-39 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS15820 20531feee7b0ee0d5d9b6f51c05403e7 388 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 128 1.1E-11 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR56_RS15820 20531feee7b0ee0d5d9b6f51c05403e7 388 Pfam PF00589 Phage integrase family 179 371 4.5E-31 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 Gene3D G3DSA:3.30.300.20 4 115 2.5E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 115 23.183 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 95 1.0E-26 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 SUPERFAMILY SSF89919 2 111 4.32E-34 T 29-03-2018 IPR023799 Ribosome-binding factor A domain CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 Pfam PF02033 Ribosome-binding factor A 6 108 3.2E-33 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR56_RS06090 cebcc644fe409b761e2a8dea60292e4a 126 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 113 2.2E-34 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 SUPERFAMILY SSF54211 1 86 6.83E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 Gene3D G3DSA:3.30.230.40 90 192 4.1E-28 T 29-03-2018 CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 9.9E-66 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 SUPERFAMILY SSF54211 87 178 4.86E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 Gene3D G3DSA:3.30.230.40 1 88 3.8E-32 T 29-03-2018 CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CWR56_RS07350 c7774bb0f100b1ad73bc38ace5e9bb12 192 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 192 40.851 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 SUPERFAMILY SSF56327 168 441 5.59E-84 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 Gene3D G3DSA:3.90.1820.10 277 442 4.8E-47 T 29-03-2018 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 Gene3D G3DSA:3.90.1820.10 1 276 3.9E-58 T 29-03-2018 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 SUPERFAMILY SSF51735 3 165 1.85E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 183 2.1E-63 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 3.5E-53 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWR56_RS04245 058e98c167aa54db082ebf487802fe7c 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 417 1.6E-49 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 Gene3D G3DSA:1.10.150.20 290 343 7.8E-7 T 29-03-2018 CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 Gene3D G3DSA:3.40.1700.10 6 142 1.6E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 SUPERFAMILY SSF143597 15 142 2.09E-29 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 279 1.7E-49 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 SUPERFAMILY SSF47781 280 342 3.08E-11 T 29-03-2018 IPR010994 RuvA domain 2-like CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 137 2.1E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR56_RS18865 80aae0e92faffb1ec380822c260af205 356 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 5 353 41.805 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 SUPERFAMILY SSF53901 3 270 1.53E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 Pfam PF02803 Thiolase, C-terminal domain 271 391 3.7E-53 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 Pfam PF00108 Thiolase, N-terminal domain 4 262 5.4E-103 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 PIRSF PIRSF000429 1 392 3.2E-138 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 9.7E-154 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 Gene3D G3DSA:3.40.47.10 1 265 5.5E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 Gene3D G3DSA:3.40.47.10 266 390 3.5E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CWR56_RS13535 11d07e64da64453f56cd9a973c53b3d4 392 SUPERFAMILY SSF53901 271 391 1.8E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 Pfam PF03466 LysR substrate binding domain 90 284 3.1E-21 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 SUPERFAMILY SSF46785 1 84 5.74E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 Gene3D G3DSA:1.10.10.10 1 91 7.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 Gene3D G3DSA:3.40.190.10 175 254 8.6E-12 T 29-03-2018 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 SUPERFAMILY SSF53850 91 288 1.86E-22 T 29-03-2018 CWR56_RS13875 07f24a08725a03cab22b8586debc12dd 289 Gene3D G3DSA:3.40.190.10 92 174 2.4E-8 T 29-03-2018 CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 SMART SM00345 16 75 2.8E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 Gene3D G3DSA:1.10.10.10 7 75 6.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 SUPERFAMILY SSF46785 4 84 4.31E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 Gene3D G3DSA:3.40.1410.10 76 244 2.3E-41 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 8.5E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 SMART SM00866 96 237 2.3E-37 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 Pfam PF07702 UTRA domain 97 237 1.0E-35 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR56_RS04590 b39d3e53a6c4dcbef53ec478ad19163b 244 SUPERFAMILY SSF64288 63 242 2.83E-49 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR56_RS04780 69aed656feedbb7d6642450b13732e2f 403 Gene3D G3DSA:3.60.21.10 1 71 5.6E-14 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS04780 69aed656feedbb7d6642450b13732e2f 403 Gene3D G3DSA:3.60.21.10 72 288 5.7E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS04780 69aed656feedbb7d6642450b13732e2f 403 SUPERFAMILY SSF56300 1 344 1.16E-54 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS04780 69aed656feedbb7d6642450b13732e2f 403 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 265 8.7E-58 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CWR56_RS04780 69aed656feedbb7d6642450b13732e2f 403 Pfam PF00149 Calcineurin-like phosphoesterase 1 236 2.7E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS09190 3c1256346a48d5306e4f572ac26d5d98 375 Pfam PF00589 Phage integrase family 172 359 2.7E-30 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS09190 3c1256346a48d5306e4f572ac26d5d98 375 SUPERFAMILY SSF56349 172 365 5.89E-30 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS09190 3c1256346a48d5306e4f572ac26d5d98 375 Gene3D G3DSA:1.10.150.130 40 170 6.5E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR56_RS09190 3c1256346a48d5306e4f572ac26d5d98 375 Gene3D G3DSA:1.10.443.10 171 367 1.5E-27 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 SUPERFAMILY SSF53822 62 335 5.5E-49 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 Pfam PF13377 Periplasmic binding protein-like domain 175 334 6.2E-27 T 29-03-2018 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 Gene3D G3DSA:3.40.50.2300 56 177 8.7E-17 T 29-03-2018 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 SUPERFAMILY SSF47413 1 59 5.25E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 SMART SM00354 1 71 3.6E-25 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 Gene3D G3DSA:3.40.50.2300 178 337 8.8E-33 T 29-03-2018 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.3E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS03770 2b08c7b20e708daf3e00b059fcb9112c 338 Gene3D G3DSA:1.10.260.40 2 55 2.1E-19 T 29-03-2018 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 422 2.9E-89 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 Gene3D G3DSA:3.65.10.10 21 232 4.6E-44 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 9 429 31.191 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 427 1.3E-102 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 PIRSF PIRSF000505 1 433 6.3E-124 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 SUPERFAMILY SSF55205 6 430 2.18E-100 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWR56_RS08850 c47267f535c99f0a65aeda14ac233cf6 437 Gene3D G3DSA:3.65.10.10 233 428 4.7E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR56_RS02075 33ba2c52fa6f1024dcb7d86761157dfa 154 SMART SM00871 5 154 2.1E-12 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS02075 33ba2c52fa6f1024dcb7d86761157dfa 154 SUPERFAMILY SSF55136 36 153 1.88E-11 T 29-03-2018 CWR56_RS02075 33ba2c52fa6f1024dcb7d86761157dfa 154 Gene3D G3DSA:3.20.80.10 3 154 1.6E-18 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS02075 33ba2c52fa6f1024dcb7d86761157dfa 154 Pfam PF06445 GyrI-like small molecule binding domain 6 153 8.4E-11 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS03350 ddebcbcecc64962ecbfc0740cdc6cecd 223 Pfam PF02080 TrkA-C domain 152 211 2.0E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS03350 ddebcbcecc64962ecbfc0740cdc6cecd 223 SUPERFAMILY SSF51735 2 133 9.46E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS03350 ddebcbcecc64962ecbfc0740cdc6cecd 223 SUPERFAMILY SSF116726 130 212 4.84E-19 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS03350 ddebcbcecc64962ecbfc0740cdc6cecd 223 Pfam PF02254 TrkA-N domain 4 119 4.9E-28 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CWR56_RS03350 ddebcbcecc64962ecbfc0740cdc6cecd 223 Gene3D G3DSA:3.40.50.720 2 134 1.5E-22 T 29-03-2018 CWR56_RS03350 ddebcbcecc64962ecbfc0740cdc6cecd 223 Gene3D G3DSA:3.30.70.1450 135 217 3.2E-18 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 Pfam PF00119 ATP synthase A chain 19 228 1.1E-49 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 PRINTS PR00123 ATP synthase A subunit signature 80 96 5.4E-13 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 PRINTS PR00123 ATP synthase A subunit signature 138 153 5.4E-13 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 PRINTS PR00123 ATP synthase A subunit signature 214 229 5.4E-13 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 PRINTS PR00123 ATP synthase A subunit signature 154 176 5.4E-13 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 Gene3D G3DSA:1.20.120.220 8 233 3.5E-41 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 SUPERFAMILY SSF81336 73 228 4.05E-31 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 Hamap MF_01393 ATP synthase subunit a [atpB]. 2 234 13.468 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17315 638d00987eaec655a15b3a8d7001e2ed 234 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 11 229 5.6E-30 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 Gene3D G3DSA:3.30.70.20 47 75 1.1E-6 T 29-03-2018 CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 Pfam PF12837 4Fe-4S binding domain 39 61 3.3E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 Pfam PF00037 4Fe-4S binding domain 13 32 2.8E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 Gene3D G3DSA:3.30.70.20 1 24 8.1E-7 T 29-03-2018 CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 SUPERFAMILY SSF54862 6 65 2.55E-15 T 29-03-2018 CWR56_RS02955 0d62e608057a15bf0f5fefed1a85e20b 76 Gene3D G3DSA:3.30.70.20 25 46 2.3E-9 T 29-03-2018 CWR56_RS10910 b8eee4faaf9e72e6512d29e62629ebdd 84 Pfam PF12645 Helix-turn-helix domain 10 74 1.8E-25 T 29-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CWR56_RS15795 356ffb81f8c4dc6f36f5a63f13390245 66 SUPERFAMILY SSF47413 2 64 8.58E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS15795 356ffb81f8c4dc6f36f5a63f13390245 66 Gene3D G3DSA:1.10.260.40 1 65 1.2E-19 T 29-03-2018 CWR56_RS15795 356ffb81f8c4dc6f36f5a63f13390245 66 SMART SM00530 4 60 5.1E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15795 356ffb81f8c4dc6f36f5a63f13390245 66 Pfam PF01381 Helix-turn-helix 5 60 7.0E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 SUPERFAMILY SSF52540 305 510 2.67E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 SUPERFAMILY SSF52540 2 244 1.43E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 Pfam PF12848 ABC transporter 228 313 4.5E-24 T 29-03-2018 IPR032781 ABC-transporter extension domain CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 SMART SM00382 26 234 3.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 SMART SM00382 347 512 6.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 Gene3D G3DSA:3.40.50.300 290 515 6.8E-39 T 29-03-2018 CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 Gene3D G3DSA:3.40.50.300 1 289 1.9E-56 T 29-03-2018 CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 Pfam PF00005 ABC transporter 17 189 1.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS03835 9e8045268aa99535c52b9c005d575b0c 516 Pfam PF00005 ABC transporter 339 467 1.6E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 Gene3D G3DSA:3.40.309.10 228 407 1.3E-61 T 29-03-2018 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 Gene3D G3DSA:3.40.605.10 1 227 4.4E-60 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 SUPERFAMILY SSF53720 2 441 4.58E-122 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 Pfam PF00171 Aldehyde dehydrogenase family 2 427 4.3E-89 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 208 215 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 236 247 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR56_RS10655 6595f83315869166d83aee104d6d13eb 454 PIRSF PIRSF036492 1 454 2.2E-186 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CWR56_RS05505 47fb30d62d08dc4ca5f591da30205d4b 145 Gene3D G3DSA:1.20.144.10 10 145 5.0E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS05505 47fb30d62d08dc4ca5f591da30205d4b 145 Pfam PF02681 Divergent PAP2 family 9 139 3.1E-47 T 29-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related CWR56_RS17815 5963c7d0717e8d1039d932e2256109d6 88 PIRSF PIRSF037257 1 87 1.6E-30 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CWR56_RS17815 5963c7d0717e8d1039d932e2256109d6 88 Pfam PF06257 Biofilm formation stimulator VEG 6 77 2.2E-29 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CWR56_RS17815 5963c7d0717e8d1039d932e2256109d6 88 Gene3D G3DSA:2.30.30.100 4 78 1.2E-29 T 29-03-2018 CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 SMART SM00448 2 112 1.6E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 Gene3D G3DSA:3.40.50.2300 1 126 3.5E-33 T 29-03-2018 CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 Pfam PF00072 Response regulator receiver domain 4 112 3.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 SMART SM00862 150 226 8.5E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 Gene3D G3DSA:1.10.10.10 127 230 2.3E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 SUPERFAMILY SSF52172 2 130 2.85E-37 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 1.7E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS04015 0152e0a067289a58c162d2141f226871 230 SUPERFAMILY SSF46894 126 227 5.1E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS16270 573844f57984ffdab0b01121530b913f 335 Pfam PF05544 Proline racemase 10 332 2.6E-130 T 29-03-2018 IPR008794 Proline racemase family CWR56_RS16270 573844f57984ffdab0b01121530b913f 335 SUPERFAMILY SSF54506 1 332 8.97E-110 T 29-03-2018 CWR56_RS16270 573844f57984ffdab0b01121530b913f 335 PIRSF PIRSF029792 1 335 4.3E-149 T 29-03-2018 IPR008794 Proline racemase family CWR56_RS16270 573844f57984ffdab0b01121530b913f 335 Gene3D G3DSA:3.10.310.10 1 152 1.1E-32 T 29-03-2018 CWR56_RS16270 573844f57984ffdab0b01121530b913f 335 Gene3D G3DSA:3.10.310.10 153 310 4.7E-62 T 29-03-2018 CWR56_RS13160 e4dae2f0672f31b0758759562ce3f303 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 399 2.3E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13160 e4dae2f0672f31b0758759562ce3f303 400 Gene3D G3DSA:3.30.565.10 218 398 2.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13160 e4dae2f0672f31b0758759562ce3f303 400 SUPERFAMILY SSF55874 259 397 9.95E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13160 e4dae2f0672f31b0758759562ce3f303 400 SMART SM00387 296 400 6.1E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13160 e4dae2f0672f31b0758759562ce3f303 400 Pfam PF07694 5TMR of 5TMR-LYT 27 190 2.3E-41 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CWR56_RS13160 e4dae2f0672f31b0758759562ce3f303 400 Pfam PF06580 Histidine kinase 205 281 4.2E-25 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 650 1.4E-235 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 SMART SM00490 490 575 8.6E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 SMART SM00487 254 444 4.2E-36 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 SUPERFAMILY SSF52540 176 438 1.5E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Pfam PF17191 RecG wedge domain 7 166 1.7E-33 T 29-03-2018 IPR033454 RecG, wedge domain CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Gene3D G3DSA:3.40.50.300 240 441 5.2E-37 T 29-03-2018 CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Pfam PF00271 Helicase conserved C-terminal domain 457 574 1.4E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 SUPERFAMILY SSF52540 370 631 3.24E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Gene3D G3DSA:2.40.50.140 58 142 8.3E-21 T 29-03-2018 CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Gene3D G3DSA:3.40.50.300 442 615 4.5E-34 T 29-03-2018 CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 SUPERFAMILY SSF50249 2 170 2.02E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Gene3D G3DSA:1.10.150.20 7 57 4.9E-4 T 29-03-2018 CWR56_RS12935 a97a6e931cad1db2661963abb44a8873 686 Pfam PF00270 DEAD/DEAH box helicase 260 418 1.1E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS09620 1bd4d698d39b32aef6ec2876824f73e7 226 Pfam PF04892 VanZ like family 40 157 5.8E-22 T 29-03-2018 IPR006976 VanZ-like CWR56_RS10050 0a58b04d498357e07fd8461b3664ef0c 644 SUPERFAMILY SSF52540 428 536 1.38E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10050 0a58b04d498357e07fd8461b3664ef0c 644 SUPERFAMILY SSF52540 283 350 1.38E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10050 0a58b04d498357e07fd8461b3664ef0c 644 Pfam PF07728 AAA domain (dynein-related subfamily) 299 508 2.0E-14 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CWR56_RS10050 0a58b04d498357e07fd8461b3664ef0c 644 Gene3D G3DSA:3.40.50.300 283 515 3.4E-23 T 29-03-2018 CWR56_RS10050 0a58b04d498357e07fd8461b3664ef0c 644 SMART SM00382 295 518 2.3E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06375 4237961014965feb426328105d12d689 509 Gene3D G3DSA:2.40.40.10 78 385 1.6E-13 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CWR56_RS06375 4237961014965feb426328105d12d689 509 Pfam PF00877 NlpC/P60 family 408 498 1.1E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS06375 4237961014965feb426328105d12d689 509 SUPERFAMILY SSF54001 392 508 1.03E-39 T 29-03-2018 CWR56_RS06375 4237961014965feb426328105d12d689 509 Gene3D G3DSA:3.90.1720.10 387 508 3.0E-37 T 29-03-2018 CWR56_RS16565 c2c73de33eb1c80af6ef12f810d8e574 119 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS16565 c2c73de33eb1c80af6ef12f810d8e574 119 SUPERFAMILY SSF54523 12 109 1.73E-13 T 29-03-2018 CWR56_RS16565 c2c73de33eb1c80af6ef12f810d8e574 119 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 1.0E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS16565 c2c73de33eb1c80af6ef12f810d8e574 119 Gene3D G3DSA:3.30.700.10 12 116 7.4E-16 T 29-03-2018 CWR56_RS16565 c2c73de33eb1c80af6ef12f810d8e574 119 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 2.7E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 Gene3D G3DSA:2.30.40.10 14 71 2.0E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 TIGRFAM TIGR01178 ade: adenine deaminase 18 565 5.1E-174 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 Gene3D G3DSA:2.30.40.10 266 352 2.2E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 SUPERFAMILY SSF51556 68 314 4.4E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 Pfam PF01979 Amidohydrolase family 64 348 2.6E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 SUPERFAMILY SSF51338 9 68 6.27E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 SUPERFAMILY SSF51338 317 348 6.27E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 Gene3D G3DSA:3.20.20.140 72 252 6.7E-8 T 29-03-2018 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 Hamap MF_01518 Adenine deaminase [ade]. 18 565 35.205 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CWR56_RS08780 5538d49277c1b0bbedb78d6165255310 565 Pfam PF13382 Adenine deaminase C-terminal domain 396 563 3.4E-60 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 67 85 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 128 140 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 31 47 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 263 278 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 280 295 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 353 366 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 163 174 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 206 233 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 PRINTS PR00992 Alanine racemase signature 300 317 1.0E-57 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 TIGRFAM TIGR00492 alr: alanine racemase 8 371 2.7E-115 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 SUPERFAMILY SSF50621 242 380 2.79E-45 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 Gene3D G3DSA:3.20.20.10 5 230 1.8E-45 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 Pfam PF00842 Alanine racemase, C-terminal domain 247 370 1.5E-44 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 Hamap MF_01201 Alanine racemase. 5 371 33.017 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 Pfam PF01168 Alanine racemase, N-terminal domain 12 233 5.1E-65 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 SMART SM01005 247 371 1.5E-61 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 Gene3D G3DSA:2.40.37.10 231 380 1.1E-56 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 SUPERFAMILY SSF51419 12 248 1.12E-63 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS17260 b84b9194c7bb67bb72ec59eba5c19f77 385 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS00665 5b7ac49a30d025eea1948eaad32475eb 319 Pfam PF01112 Asparaginase 15 286 4.5E-65 T 29-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 CWR56_RS00665 5b7ac49a30d025eea1948eaad32475eb 319 Gene3D G3DSA:3.60.20.30 150 290 1.3E-37 T 29-03-2018 CWR56_RS00665 5b7ac49a30d025eea1948eaad32475eb 319 SUPERFAMILY SSF56235 2 286 1.0E-76 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 Gene3D G3DSA:1.10.10.10 5 89 4.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 SUPERFAMILY SSF46785 20 91 7.04E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 Gene3D G3DSA:3.40.640.10 118 366 7.2E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 SUPERFAMILY SSF53383 105 459 5.24E-63 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 Pfam PF00155 Aminotransferase class I and II 132 450 5.8E-23 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 Gene3D G3DSA:3.90.1150.10 367 461 3.9E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 SMART SM00345 28 87 1.5E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS11330 56e16c7534ca5ee0cce233ed1db9b0c1 461 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 87 1.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 Pfam PF02803 Thiolase, C-terminal domain 256 377 4.9E-25 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 Pfam PF00108 Thiolase, N-terminal domain 4 247 4.4E-40 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 SUPERFAMILY SSF53901 256 377 1.78E-26 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 376 2.6E-99 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 Gene3D G3DSA:3.40.47.10 266 378 1.7E-13 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 Gene3D G3DSA:3.40.47.10 1 261 1.2E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 PIRSF PIRSF000429 1 378 1.2E-86 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 ProSitePatterns PS00737 Thiolases signature 2. 324 340 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CWR56_RS14780 c3ecd80dbcf67d8978232e93b5fdc2c1 378 SUPERFAMILY SSF53901 3 251 2.56E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR56_RS17825 5d61f65a9ddc2d0099295af9198d29c6 312 SUPERFAMILY SSF51556 1 312 3.18E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS17825 5d61f65a9ddc2d0099295af9198d29c6 312 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 310 4.9E-98 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CWR56_RS17825 5d61f65a9ddc2d0099295af9198d29c6 312 Gene3D G3DSA:3.20.20.140 1 236 2.3E-77 T 29-03-2018 CWR56_RS17825 5d61f65a9ddc2d0099295af9198d29c6 312 Gene3D G3DSA:3.20.20.140 237 312 6.3E-24 T 29-03-2018 CWR56_RS18020 63c284bfd1f6a09ebf8ff3c18a01409e 305 Pfam PF01458 Uncharacterized protein family (UPF0051) 78 303 2.6E-45 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CWR56_RS18020 63c284bfd1f6a09ebf8ff3c18a01409e 305 SUPERFAMILY SSF101960 48 304 1.96E-41 T 29-03-2018 CWR56_RS07590 ddf41081b29743056522c2ae72103936 103 Gene3D G3DSA:3.40.1440.10 1 81 1.1E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS07590 ddf41081b29743056522c2ae72103936 103 SMART SM00465 1 80 0.0037 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS07590 ddf41081b29743056522c2ae72103936 103 Pfam PF01541 GIY-YIG catalytic domain 2 72 5.5E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS07590 ddf41081b29743056522c2ae72103936 103 SUPERFAMILY SSF82771 2 72 4.58E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS16340 0915527028a8543026837ae072cdaa76 178 SUPERFAMILY SSF46785 12 86 1.04E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16340 0915527028a8543026837ae072cdaa76 178 Gene3D G3DSA:1.10.10.10 1 112 7.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16340 0915527028a8543026837ae072cdaa76 178 Pfam PF14277 Domain of unknown function (DUF4364) 13 173 6.6E-54 T 29-03-2018 IPR025374 Protein of unknown function DUF4364 CWR56_RS18935 98713712926fc02376e352d504e0235d 100 Gene3D G3DSA:3.40.50.2300 5 99 1.8E-22 T 29-03-2018 CWR56_RS18935 98713712926fc02376e352d504e0235d 100 SUPERFAMILY SSF52794 8 98 2.51E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS18935 98713712926fc02376e352d504e0235d 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 9 92 1.2E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 Gene3D G3DSA:3.50.50.60 256 340 3.1E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 292 1.3E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 Gene3D G3DSA:3.50.50.60 1 123 1.8E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 Gene3D G3DSA:3.30.390.30 341 444 5.2E-24 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 SUPERFAMILY SSF51905 1 317 4.81E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 7.7E-17 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.7E-17 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 7.7E-17 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 7.7E-17 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 432 7.6E-17 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 Gene3D G3DSA:3.50.50.60 124 255 6.5E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.2E-25 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.2E-25 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 1.2E-25 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 1.2E-25 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.2E-25 T 29-03-2018 CWR56_RS12840 16985fe23fd1b8fe0630e08462d62205 444 SUPERFAMILY SSF55424 325 441 7.56E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS01055 55dcca180acacc3abe1dce414a8c318e 97 Gene3D G3DSA:1.20.1260.10 1 74 2.5E-7 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS01055 55dcca180acacc3abe1dce414a8c318e 97 Pfam PF07875 Coat F domain 16 77 4.8E-19 T 29-03-2018 IPR012851 Spore coat protein CotF-like CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 SMART SM00534 422 597 5.7E-12 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 Pfam PF00488 MutS domain V 425 596 4.7E-26 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 Gene3D G3DSA:3.40.50.300 386 598 6.8E-19 T 29-03-2018 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 SUPERFAMILY SSF48334 125 185 6.15E-5 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 PIRSF PIRSF037677 355 598 1.6E-34 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 PIRSF PIRSF037677 114 185 0.022 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 Gene3D G3DSA:1.10.1420.10 110 383 5.0E-24 T 29-03-2018 CWR56_RS16965 19228814395b3007c95bbfae23c44c9f 598 SUPERFAMILY SSF52540 393 597 1.81E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 69 82 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 420 434 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 34 49 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 112 126 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 504 521 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 268 281 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 565 581 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 486 502 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR00418 DNA topoisomerase II family signature 524 536 1.2E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Pfam PF00204 DNA gyrase B 221 390 1.3E-62 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Gene3D G3DSA:3.40.50.670 399 630 4.8E-107 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 561 622 3.2E-31 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 SMART SM00433 34 626 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 633 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Gene3D G3DSA:3.30.230.10 220 392 1.4E-64 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 SUPERFAMILY SSF54211 221 391 2.85E-60 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Pfam PF01751 Toprim domain 419 527 1.2E-17 T 29-03-2018 IPR006171 TOPRIM domain CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Gene3D G3DSA:3.30.565.10 17 219 9.6E-75 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 194 207 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 586 598 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 374 394 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 220 242 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 179 194 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 360 374 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 312 328 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 602 618 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 470 479 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 PRINTS PR01159 DNA gyrase subunit B signature 5 15 1.1E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 SUPERFAMILY SSF56719 394 624 1.96E-91 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 SUPERFAMILY SSF55874 5 212 1.57E-70 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 633 93.746 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 173 2.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18460 8d16270ec541b64e3282c86d0ae452be 633 SMART SM00387 30 174 5.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01300 d49d83069f132308a5aead8569848d70 327 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 251 325 2.0E-24 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CWR56_RS01300 d49d83069f132308a5aead8569848d70 327 Pfam PF00460 Flagella basal body rod protein 5 35 3.7E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CWR56_RS01300 d49d83069f132308a5aead8569848d70 327 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 139 1.1E-31 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CWR56_RS01300 d49d83069f132308a5aead8569848d70 327 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 238 308 9.4E-22 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CWR56_RS01300 d49d83069f132308a5aead8569848d70 327 SUPERFAMILY SSF117143 92 287 9.55E-23 T 29-03-2018 CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 TIGRFAM TIGR03527 selenium_YedF: selenium metabolism protein YedF 5 200 2.5E-72 T 29-03-2018 IPR019870 Selenium metabolism protein YedF CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 Pfam PF01206 Sulfurtransferase TusA 3 71 1.2E-15 T 29-03-2018 IPR001455 TusA-like domain CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 Pfam PF02635 DsrE/DsrF-like family 139 198 1.8E-4 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 SUPERFAMILY SSF64307 3 72 1.16E-13 T 29-03-2018 IPR001455 TusA-like domain CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 SUPERFAMILY SSF75169 104 197 9.12E-11 T 29-03-2018 IPR027396 DsrEFH-like CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 Gene3D G3DSA:3.40.1260.10 92 199 3.4E-10 T 29-03-2018 CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 5 29 - T 29-03-2018 IPR001455 TusA-like domain CWR56_RS18365 7eea29663166c39403021a27cb70e719 200 Gene3D G3DSA:3.30.110.40 2 87 4.6E-14 T 29-03-2018 IPR001455 TusA-like domain CWR56_RS03125 d57a6b9f1efb4efbfed33cee43e3c6d3 184 Gene3D G3DSA:1.10.10.10 70 184 6.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03125 d57a6b9f1efb4efbfed33cee43e3c6d3 184 Pfam PF12645 Helix-turn-helix domain 6 46 1.4E-4 T 29-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CWR56_RS03125 d57a6b9f1efb4efbfed33cee43e3c6d3 184 Pfam PF08281 Sigma-70, region 4 127 174 6.2E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03125 d57a6b9f1efb4efbfed33cee43e3c6d3 184 SUPERFAMILY SSF88659 119 179 1.1E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS08550 d433618ca70c25f1d57cbfcd9a7efb5a 223 Gene3D G3DSA:3.40.50.300 1 222 1.2E-68 T 29-03-2018 CWR56_RS08550 d433618ca70c25f1d57cbfcd9a7efb5a 223 PIRSF PIRSF039085 1 223 2.5E-82 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWR56_RS08550 d433618ca70c25f1d57cbfcd9a7efb5a 223 SUPERFAMILY SSF52540 1 219 4.62E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08550 d433618ca70c25f1d57cbfcd9a7efb5a 223 SMART SM00382 26 219 2.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS08550 d433618ca70c25f1d57cbfcd9a7efb5a 223 Pfam PF00005 ABC transporter 17 164 8.9E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Gene3D G3DSA:3.30.310.50 389 498 4.9E-10 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 SUPERFAMILY SSF53738 282 395 1.49E-16 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 SUPERFAMILY SSF53738 167 278 9.81E-25 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 SUPERFAMILY SSF53738 12 200 2.86E-27 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 282 396 5.0E-15 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 142 6.4E-27 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Gene3D G3DSA:3.40.120.10 284 388 6.5E-22 T 29-03-2018 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 SUPERFAMILY SSF55957 426 494 2.59E-5 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Gene3D G3DSA:3.40.120.10 178 283 2.7E-27 T 29-03-2018 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Gene3D G3DSA:3.40.120.10 6 177 1.6E-29 T 29-03-2018 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 193 212 6.8E-20 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 228 241 6.8E-20 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 6.8E-20 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 257 272 6.8E-20 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS11520 09a51f304cb383a2735ff239af414389 500 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 176 277 1.7E-21 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR56_RS13645 8e9910be1a4092070eceebe129d49d05 396 Gene3D G3DSA:3.90.1150.10 283 395 2.1E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS13645 8e9910be1a4092070eceebe129d49d05 396 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 6 392 3.8E-137 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR56_RS13645 8e9910be1a4092070eceebe129d49d05 396 Gene3D G3DSA:3.40.640.10 104 282 2.5E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS13645 8e9910be1a4092070eceebe129d49d05 396 Pfam PF00155 Aminotransferase class I and II 49 389 2.8E-39 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS13645 8e9910be1a4092070eceebe129d49d05 396 Gene3D G3DSA:3.90.1150.10 2 103 4.4E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS13645 8e9910be1a4092070eceebe129d49d05 396 SUPERFAMILY SSF53383 3 395 4.57E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS16060 6778dc9ec7ba6191b84bad5db6d3d68c 416 Gene3D G3DSA:1.20.1250.20 215 412 3.7E-15 T 29-03-2018 CWR56_RS16060 6778dc9ec7ba6191b84bad5db6d3d68c 416 Pfam PF05977 Transmembrane secretion effector 17 397 4.3E-25 T 29-03-2018 IPR010290 Transmembrane secretion effector CWR56_RS16060 6778dc9ec7ba6191b84bad5db6d3d68c 416 Gene3D G3DSA:1.20.1250.20 3 210 1.9E-19 T 29-03-2018 CWR56_RS16060 6778dc9ec7ba6191b84bad5db6d3d68c 416 SUPERFAMILY SSF103473 1 402 4.45E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS11085 0aa247d0c7272033357ba3201d32298d 126 SUPERFAMILY SSF55729 12 115 4.15E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS11085 0aa247d0c7272033357ba3201d32298d 126 Pfam PF13673 Acetyltransferase (GNAT) domain 30 117 2.1E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS11085 0aa247d0c7272033357ba3201d32298d 126 Gene3D G3DSA:3.40.630.30 1 121 1.0E-15 T 29-03-2018 CWR56_RS09245 54abb2b405eec204e13f5082532a6f92 214 Pfam PF02390 Putative methyltransferase 39 207 4.0E-44 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWR56_RS09245 54abb2b405eec204e13f5082532a6f92 214 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 213 3.0E-53 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWR56_RS09245 54abb2b405eec204e13f5082532a6f92 214 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 213 28.129 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWR56_RS09245 54abb2b405eec204e13f5082532a6f92 214 Gene3D G3DSA:3.40.50.150 1 212 1.1E-24 T 29-03-2018 CWR56_RS09245 54abb2b405eec204e13f5082532a6f92 214 SUPERFAMILY SSF53335 22 211 3.98E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS12250 0f0d1a4f793c585132a3cbb9cf613c1b 179 SUPERFAMILY SSF53323 3 178 4.84E-39 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CWR56_RS12250 0f0d1a4f793c585132a3cbb9cf613c1b 179 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 177 1.6E-39 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS12250 0f0d1a4f793c585132a3cbb9cf613c1b 179 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 3 177 1.3E-23 T 29-03-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CWR56_RS12250 0f0d1a4f793c585132a3cbb9cf613c1b 179 Gene3D G3DSA:3.40.920.10 3 178 1.4E-44 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS03845 44289901483c7f20ba80ac920585a9e5 86 Pfam PF04071 Cysteine-rich small domain 4 85 1.1E-30 T 29-03-2018 IPR007212 Cysteine-rich small domain CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 160 1.5E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 324 1.8E-131 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 Gene3D G3DSA:3.90.650.10 168 357 8.2E-57 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 SUPERFAMILY SSF55326 1 167 1.94E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 324 2.5E-28 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 357 44.668 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 Gene3D G3DSA:3.30.1330.10 30 158 4.7E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CWR56_RS01095 375f403b7a0c54ae54ee628c6badc3fe 358 SUPERFAMILY SSF56042 169 355 5.06E-51 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR56_RS12105 ada7fe952c2e9a8c1ee0e7b49e09161f 286 Gene3D G3DSA:3.40.50.620 22 266 4.6E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS12105 ada7fe952c2e9a8c1ee0e7b49e09161f 286 SUPERFAMILY SSF52402 31 229 2.87E-47 T 29-03-2018 CWR56_RS12105 ada7fe952c2e9a8c1ee0e7b49e09161f 286 Pfam PF01171 PP-loop family 55 218 9.2E-17 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CWR56_RS12105 ada7fe952c2e9a8c1ee0e7b49e09161f 286 PIRSF PIRSF004976 13 284 4.8E-70 T 29-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CWR56_RS18100 c6dc4e72642ec87f04bd22328384b476 720 Pfam PF07242 Protein of unknown function (DUF1430) 617 718 9.7E-22 T 29-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 Gene3D G3DSA:3.20.20.70 1 321 7.0E-155 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 264 279 4.6E-61 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 293 312 4.6E-61 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 239 255 4.6E-61 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 149 168 4.6E-61 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 118 132 4.6E-61 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 187 206 4.6E-61 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 SUPERFAMILY SSF51569 2 320 4.25E-144 T 29-03-2018 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 SMART SM01004 1 319 1.7E-240 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 Pfam PF00490 Delta-aminolevulinic acid dehydratase 3 317 2.5E-151 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 239 251 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS17035 c1eb533dd6310e6c23228715ef9b2cf9 321 PIRSF PIRSF001415 1 321 6.9E-151 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR56_RS14195 1b5129c5c0f6a9663d4dcef2e7d4e93a 467 SUPERFAMILY SSF55797 325 462 1.33E-10 T 29-03-2018 IPR014044 CAP domain CWR56_RS14195 1b5129c5c0f6a9663d4dcef2e7d4e93a 467 Pfam PF00188 Cysteine-rich secretory protein family 328 454 6.9E-9 T 29-03-2018 IPR014044 CAP domain CWR56_RS14195 1b5129c5c0f6a9663d4dcef2e7d4e93a 467 Pfam PF04122 Putative cell wall binding repeat 2 218 290 2.0E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14195 1b5129c5c0f6a9663d4dcef2e7d4e93a 467 Pfam PF04122 Putative cell wall binding repeat 2 128 210 4.2E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14195 1b5129c5c0f6a9663d4dcef2e7d4e93a 467 Pfam PF04122 Putative cell wall binding repeat 2 33 116 5.6E-18 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14195 1b5129c5c0f6a9663d4dcef2e7d4e93a 467 Gene3D G3DSA:3.40.33.10 313 466 4.3E-8 T 29-03-2018 IPR014044 CAP domain CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 Pfam PF00551 Formyl transferase 1 178 4.9E-46 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 36.046 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 SUPERFAMILY SSF50486 205 308 2.04E-29 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 SUPERFAMILY SSF53328 1 205 1.83E-71 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 300 4.2E-98 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 Gene3D G3DSA:3.10.25.10 206 306 2.6E-28 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 Pfam PF02911 Formyl transferase, C-terminal domain 206 299 6.1E-27 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 Gene3D G3DSA:3.40.50.170 1 205 1.8E-72 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS13065 2ad000fdaf7df122dc5931effeddb353 309 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR56_RS07620 0cb63051eae8b2bbe0d200475475ec37 320 SMART SM00382 29 213 2.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07620 0cb63051eae8b2bbe0d200475475ec37 320 Pfam PF00005 ABC transporter 20 163 2.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07620 0cb63051eae8b2bbe0d200475475ec37 320 Gene3D G3DSA:3.40.50.300 2 271 1.6E-62 T 29-03-2018 CWR56_RS07620 0cb63051eae8b2bbe0d200475475ec37 320 SUPERFAMILY SSF52540 3 225 6.59E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07620 0cb63051eae8b2bbe0d200475475ec37 320 Pfam PF13732 Domain of unknown function (DUF4162) 218 307 9.0E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CWR56_RS08995 3a2c0e0cdaa971b412800b1c2c14c702 262 SUPERFAMILY SSF53187 2 170 7.85E-32 T 29-03-2018 CWR56_RS08995 3a2c0e0cdaa971b412800b1c2c14c702 262 SMART SM00646 62 169 5.9E-7 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS08995 3a2c0e0cdaa971b412800b1c2c14c702 262 Gene3D G3DSA:3.40.630.40 1 173 1.9E-32 T 29-03-2018 CWR56_RS08995 3a2c0e0cdaa971b412800b1c2c14c702 262 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 3 169 4.9E-31 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS04460 616edd52f54ac6c14e942f9155f7faa7 145 Pfam PF06695 Putative small multi-drug export protein 16 136 1.3E-34 T 29-03-2018 IPR009577 Putative small multi-drug export CWR56_RS16300 b9bdf19d87a9cbfc7e08f7d21b44b61b 626 Gene3D G3DSA:3.40.50.40 460 575 8.3E-4 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CWR56_RS16300 b9bdf19d87a9cbfc7e08f7d21b44b61b 626 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 175 517 2.0E-22 T 29-03-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CWR56_RS16300 b9bdf19d87a9cbfc7e08f7d21b44b61b 626 TIGRFAM TIGR04480 D_pro_red_PrdA: D-proline reductase (dithiol), PrdA proprotein 4 594 4.0E-304 T 29-03-2018 IPR031002 D-proline reductase, PrdA proprotein GO:0050002|GO:0055114 KEGG: 00330+1.21.4.1 CWR56_RS04705 59cfb7ac1a862c0012810330bf129739 693 Pfam PF03170 Bacterial cellulose synthase subunit 30 602 5.3E-77 T 29-03-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 TIGRFAM TIGR00595 priA: primosomal protein N' 309 825 1.5E-188 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 Gene3D G3DSA:3.40.50.300 270 473 2.4E-26 T 29-03-2018 CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 SUPERFAMILY SSF52540 553 734 2.83E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 Pfam PF04851 Type III restriction enzyme, res subunit 283 448 2.6E-18 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 828 23.055 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 SMART SM00490 583 680 4.2E-12 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 Pfam PF00271 Helicase conserved C-terminal domain 590 679 1.8E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 Gene3D G3DSA:3.40.50.300 481 722 2.8E-23 T 29-03-2018 CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 SUPERFAMILY SSF52540 223 465 4.64E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13075 43759188885e1dd2b93366bdc8c7ec31 829 SMART SM00487 281 480 1.9E-21 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS11525 5021a002c78d6f78641c3cd6acbb308a 221 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 198 1.4E-55 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS11525 5021a002c78d6f78641c3cd6acbb308a 221 SUPERFAMILY SSF51366 2 218 8.63E-49 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS11525 5021a002c78d6f78641c3cd6acbb308a 221 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS11525 5021a002c78d6f78641c3cd6acbb308a 221 Gene3D G3DSA:3.20.20.70 1 221 1.9E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS12890 611ed88ab5cd102b14d25b06a85efd19 425 Pfam PF13416 Bacterial extracellular solute-binding protein 60 358 1.3E-39 T 29-03-2018 CWR56_RS12890 611ed88ab5cd102b14d25b06a85efd19 425 SUPERFAMILY SSF53850 22 423 5.43E-82 T 29-03-2018 CWR56_RS12890 611ed88ab5cd102b14d25b06a85efd19 425 Gene3D G3DSA:3.40.190.10 31 165 1.3E-21 T 29-03-2018 CWR56_RS12890 611ed88ab5cd102b14d25b06a85efd19 425 Gene3D G3DSA:3.40.190.10 166 425 1.4E-39 T 29-03-2018 CWR56_RS02970 acfddec5c3dcd32e0308a8f7a265d06f 457 PIRSF PIRSF006603 3 452 6.3E-88 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS02970 acfddec5c3dcd32e0308a8f7a265d06f 457 Pfam PF01554 MatE 250 408 3.0E-17 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS02970 acfddec5c3dcd32e0308a8f7a265d06f 457 Pfam PF01554 MatE 29 189 5.7E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS02970 acfddec5c3dcd32e0308a8f7a265d06f 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 29 420 1.4E-63 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 166 665 3.7E-69 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 617 642 2.4E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 558 574 2.4E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 586 602 2.4E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 Pfam PF00702 haloacid dehalogenase-like hydrolase 381 599 3.8E-36 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 SUPERFAMILY SSF56784 442 686 1.22E-44 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 SUPERFAMILY SSF56784 382 402 1.22E-44 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 Gene3D G3DSA:3.40.50.1000 512 647 1.1E-33 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 SUPERFAMILY SSF81653 197 292 7.19E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 Gene3D G3DSA:2.70.150.10 56 293 1.2E-25 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 242 256 2.5E-23 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 543 2.5E-23 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 621 2.5E-23 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 521 2.5E-23 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 605 2.5E-23 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 384 398 2.5E-23 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 143 687 2.0E-149 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 Gene3D G3DSA:3.40.1110.10 395 511 5.8E-19 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 Pfam PF00122 E1-E2 ATPase 193 362 3.8E-36 T 29-03-2018 CWR56_RS02750 ab565f062bc8ab659d449dc7c75a4255 699 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 386 392 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR56_RS01045 9a624832bc81e5dffc1a063e35e105b5 421 Gene3D G3DSA:3.20.20.70 10 293 1.4E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS01045 9a624832bc81e5dffc1a063e35e105b5 421 Gene3D G3DSA:1.10.400.20 294 408 2.6E-23 T 29-03-2018 CWR56_RS01045 9a624832bc81e5dffc1a063e35e105b5 421 Pfam PF08013 Tagatose 6 phosphate kinase 12 394 2.4E-15 T 29-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 CWR56_RS01045 9a624832bc81e5dffc1a063e35e105b5 421 SUPERFAMILY SSF51569 11 411 5.13E-107 T 29-03-2018 CWR56_RS01045 9a624832bc81e5dffc1a063e35e105b5 421 PIRSF PIRSF009264 5 415 1.8E-111 T 29-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 SUPERFAMILY SSF55031 191 379 2.41E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 SUPERFAMILY SSF53187 8 191 2.1E-58 T 29-03-2018 CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 SUPERFAMILY SSF53187 383 465 2.1E-58 T 29-03-2018 CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 17 461 3.9E-109 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 Gene3D G3DSA:3.40.630.10 3 205 1.3E-27 T 29-03-2018 CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 Pfam PF01546 Peptidase family M20/M25/M40 89 461 3.8E-27 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS15495 172fb0cde8e5036fc3a7a2400b1154aa 467 Gene3D G3DSA:3.30.70.360 276 370 4.3E-14 T 29-03-2018 CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 SUPERFAMILY SSF54862 285 361 1.21E-19 T 29-03-2018 CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 Pfam PF14697 4Fe-4S dicluster domain 289 339 2.6E-10 T 29-03-2018 CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 Gene3D G3DSA:3.30.70.20 257 304 6.8E-5 T 29-03-2018 CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 Gene3D G3DSA:3.30.70.20 305 329 9.9E-11 T 29-03-2018 CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 295 306 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 Gene3D G3DSA:1.10.10.10 27 100 1.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06910 053c41e0c6172f9181c64334be9e5767 424 Gene3D G3DSA:3.30.70.20 330 374 4.9E-6 T 29-03-2018 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 ProSitePatterns PS00760 Signal peptidases I lysine active site. 86 98 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 3.4E-18 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 129 148 3.4E-18 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 84 96 3.4E-18 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 171 9.9E-48 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 SUPERFAMILY SSF51306 29 177 2.24E-44 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 Gene3D G3DSA:2.10.109.10 24 178 6.3E-41 T 29-03-2018 CWR56_RS02550 216a93150790a7631bbbf69edd14a7a5 178 Pfam PF00717 Peptidase S24-like 35 108 1.2E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS12535 7d699aea31259069d4b8457d6defa438 279 Pfam PF06725 3D domain 218 279 2.0E-17 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CWR56_RS12535 7d699aea31259069d4b8457d6defa438 279 Gene3D G3DSA:2.40.40.10 84 276 1.4E-41 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CWR56_RS12535 7d699aea31259069d4b8457d6defa438 279 SUPERFAMILY SSF50685 216 260 8.72E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CWR56_RS12535 7d699aea31259069d4b8457d6defa438 279 SMART SM01208 86 164 3.8E-22 T 29-03-2018 IPR011098 G5 domain CWR56_RS12535 7d699aea31259069d4b8457d6defa438 279 Pfam PF07501 G5 domain 89 163 1.6E-19 T 29-03-2018 IPR011098 G5 domain CWR56_RS12535 7d699aea31259069d4b8457d6defa438 279 Pfam PF03990 Domain of unknown function (DUF348) 33 69 3.2E-10 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 SMART SM00448 2 112 6.5E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 Gene3D G3DSA:1.10.10.10 126 229 3.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 SUPERFAMILY SSF52172 1 125 2.28E-39 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 Pfam PF00072 Response regulator receiver domain 4 112 1.8E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 4.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 Gene3D G3DSA:3.40.50.2300 1 125 3.1E-35 T 29-03-2018 CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 SUPERFAMILY SSF46894 130 227 3.4E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS11355 3ca1fb1763e8bf5bba8e780fb7be0fb4 230 SMART SM00862 151 227 3.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 75 4.0E-22 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 SMART SM00382 144 330 1.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 SUPERFAMILY SSF52540 79 350 3.12E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 Gene3D G3DSA:3.40.50.300 78 350 3.4E-96 T 29-03-2018 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 SUPERFAMILY SSF47917 348 461 3.92E-52 T 29-03-2018 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 4 461 5.9E-257 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 Gene3D G3DSA:2.40.10.170 1 77 5.1E-31 T 29-03-2018 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 Hamap MF_01347 ATP synthase subunit beta [atpB]. 2 463 58.563 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 345 6.1E-68 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 Gene3D G3DSA:1.10.1140.10 351 461 5.6E-44 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 SUPERFAMILY SSF50615 3 77 6.8E-25 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17285 c55dfe099830a3d2f61c80ceb5785164 464 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 336 345 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS09880 0a5097be0e3d541140fcb5c196fbde54 212 PIRSF PIRSF020269 1 212 1.2E-88 T 29-03-2018 IPR009501 Uncharacterised conserved protein UCP020269 CWR56_RS09880 0a5097be0e3d541140fcb5c196fbde54 212 Pfam PF02589 LUD domain 13 206 7.5E-62 T 29-03-2018 IPR003741 LUD domain CWR56_RS09880 0a5097be0e3d541140fcb5c196fbde54 212 SUPERFAMILY SSF100950 11 158 1.19E-6 T 29-03-2018 CWR56_RS09880 0a5097be0e3d541140fcb5c196fbde54 212 Gene3D G3DSA:3.40.50.10420 7 174 6.0E-27 T 29-03-2018 CWR56_RS16240 afe5614f6f655a646ce681412290fc47 427 Gene3D G3DSA:1.10.4100.10 254 385 1.0E-12 T 29-03-2018 CWR56_RS16240 afe5614f6f655a646ce681412290fc47 427 PIRSF PIRSF006054 1 424 2.7E-150 T 29-03-2018 IPR021144 Uncharacterised protein family UPF0597 CWR56_RS16240 afe5614f6f655a646ce681412290fc47 427 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 1 422 36.16 T 29-03-2018 IPR021144 Uncharacterised protein family UPF0597 CWR56_RS16240 afe5614f6f655a646ce681412290fc47 427 Pfam PF03313 Serine dehydratase alpha chain 78 417 3.2E-53 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 SUPERFAMILY SSF51206 6 153 4.19E-29 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 SMART SM00100 17 141 3.8E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 Gene3D G3DSA:1.10.10.10 158 226 2.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 Gene3D G3DSA:2.60.120.10 6 157 3.5E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 Pfam PF00027 Cyclic nucleotide-binding domain 38 124 1.5E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 SUPERFAMILY SSF46785 161 223 3.04E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10465 383c19b46feb64ec86dac0f5abd2682c 227 Pfam PF13545 Crp-like helix-turn-helix domain 174 222 9.1E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS05865 73585c989b381a99549b62c573982304 365 SUPERFAMILY SSF103473 176 317 7.85E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS05865 73585c989b381a99549b62c573982304 365 Gene3D G3DSA:3.40.1710.10 48 193 2.7E-5 T 29-03-2018 CWR56_RS05865 73585c989b381a99549b62c573982304 365 Pfam PF12698 ABC-2 family transporter protein 22 355 2.6E-29 T 29-03-2018 CWR56_RS07475 dbd5c165f74cb4ef18b9e33273a41b7c 279 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 17 268 7.7E-37 T 29-03-2018 IPR017039 Virulence factor BrkB CWR56_RS07475 dbd5c165f74cb4ef18b9e33273a41b7c 279 Pfam PF03631 Virulence factor BrkB 19 268 1.2E-59 T 29-03-2018 IPR017039 Virulence factor BrkB CWR56_RS07475 dbd5c165f74cb4ef18b9e33273a41b7c 279 PIRSF PIRSF035875 4 277 1.2E-65 T 29-03-2018 IPR017039 Virulence factor BrkB CWR56_RS13625 18c06f4d45235813875cb68892654f71 358 Gene3D G3DSA:3.90.1150.10 263 358 4.4E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS13625 18c06f4d45235813875cb68892654f71 358 Gene3D G3DSA:3.40.640.10 59 262 2.5E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS13625 18c06f4d45235813875cb68892654f71 358 SUPERFAMILY SSF53383 4 356 2.45E-66 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS13625 18c06f4d45235813875cb68892654f71 358 Pfam PF00155 Aminotransferase class I and II 22 353 1.5E-40 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 Gene3D G3DSA:2.40.50.140 986 1085 1.7E-12 T 29-03-2018 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 298 719 2.3E-178 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1043 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 Pfam PF02811 PHP domain 7 179 1.3E-54 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 Gene3D G3DSA:1.10.150.280 787 894 4.4E-10 T 29-03-2018 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 SUPERFAMILY SSF89550 5 269 1.8E-40 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 SMART SM00481 6 73 1.3E-32 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 Pfam PF14579 Helix-hairpin-helix motif 810 897 2.5E-26 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS16905 d77d79444440b7350d0769f26d19c72a 1189 Gene3D G3DSA:3.20.20.140 4 261 3.0E-58 T 29-03-2018 CWR56_RS10110 712834cfc221774aa838527e72bb50d4 235 SMART SM00382 26 217 2.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS10110 712834cfc221774aa838527e72bb50d4 235 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS10110 712834cfc221774aa838527e72bb50d4 235 Gene3D G3DSA:3.40.50.300 1 229 8.4E-60 T 29-03-2018 CWR56_RS10110 712834cfc221774aa838527e72bb50d4 235 Pfam PF00005 ABC transporter 18 160 1.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10110 712834cfc221774aa838527e72bb50d4 235 SUPERFAMILY SSF52540 2 224 8.21E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08790 b8490dffa1f1307499c6c71a443a3997 247 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 247 29.964 T 29-03-2018 IPR005583 Peroxide stress protein YaaA CWR56_RS08790 b8490dffa1f1307499c6c71a443a3997 247 Pfam PF03883 Peroxide stress protein YaaA 1 235 9.5E-77 T 29-03-2018 IPR005583 Peroxide stress protein YaaA CWR56_RS15715 b095a0b20c64b01ff8aff60a436b265d 64 Pfam PF11337 Protein of unknown function (DUF3139) 3 63 3.3E-8 T 29-03-2018 IPR021486 Protein of unknown function DUF3139 CWR56_RS02915 0e16efa69cad66da5a6ee618561e429f 49 Pfam PF12841 YvrJ protein family 8 42 1.1E-18 T 29-03-2018 IPR024419 Protein of unknown function YvrJ CWR56_RS01970 f787e1b76990d65de913a7e88505c9ba 75 Pfam PF01381 Helix-turn-helix 11 62 6.2E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS01970 f787e1b76990d65de913a7e88505c9ba 75 Gene3D G3DSA:1.10.3100.10 1 74 2.4E-17 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS01970 f787e1b76990d65de913a7e88505c9ba 75 SUPERFAMILY SSF47413 2 71 4.56E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS01970 f787e1b76990d65de913a7e88505c9ba 75 SMART SM00530 10 65 2.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 471 593 6.9E-49 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 SUPERFAMILY SSF51261 465 612 1.92E-52 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 471 590 3.3E-44 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 SUPERFAMILY SSF55604 6 79 1.7E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 533 545 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 Gene3D G3DSA:2.70.70.10 457 618 3.4E-56 T 29-03-2018 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 Gene3D G3DSA:3.30.1360.60 2 75 2.5E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 616 6.3E-201 T 29-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 Pfam PF00367 phosphotransferase system, EIIB 9 41 3.9E-12 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 Pfam PF02378 Phosphotransferase system, EIIC 106 374 6.4E-21 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS01845 faa800403c09e971d66c0122cfe391a7 620 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 SUPERFAMILY SSF51905 2 197 2.35E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 SUPERFAMILY SSF51905 152 318 2.07E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 SUPERFAMILY SSF55424 323 447 9.97E-27 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Gene3D G3DSA:3.30.390.30 339 447 2.5E-23 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 9.2E-24 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 9.2E-24 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 9.2E-24 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 9.2E-24 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 9.2E-24 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 2.3E-18 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.3E-18 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 2.3E-18 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 2.3E-18 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 402 2.3E-18 T 29-03-2018 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 288 6.0E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Gene3D G3DSA:3.50.50.60 125 252 7.9E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Gene3D G3DSA:3.40.250.10 448 537 1.4E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Gene3D G3DSA:3.50.50.60 253 338 2.4E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 433 9.3E-15 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 SUPERFAMILY SSF52821 474 535 6.31E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS08655 9f1dea22a51cef11d9a0a9d54778c449 543 Gene3D G3DSA:3.50.50.60 1 124 9.0E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS07780 f639ae9acc1c61e210178cf9982ba731 192 Pfam PF02342 TerD domain 1 188 1.5E-82 T 29-03-2018 IPR003325 TerD domain GO:0006950 CWR56_RS07780 f639ae9acc1c61e210178cf9982ba731 192 Gene3D G3DSA:2.60.60.30 19 187 4.3E-61 T 29-03-2018 CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 SMART SM00382 358 543 2.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 Gene3D G3DSA:3.40.50.300 316 574 1.0E-68 T 29-03-2018 CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 Pfam PF00664 ABC transporter transmembrane region 17 280 1.9E-36 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 Gene3D G3DSA:1.20.1560.10 1 315 3.4E-66 T 29-03-2018 CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 SUPERFAMILY SSF90123 3 314 2.62E-69 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 SUPERFAMILY SSF52540 325 568 7.78E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14300 de88a67565110adf32b5743886dc7368 575 Pfam PF00005 ABC transporter 349 496 1.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS12785 800d2a9b7f4f6a093c3decad7e157bba 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 67 6.3E-6 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CWR56_RS12785 800d2a9b7f4f6a093c3decad7e157bba 103 SUPERFAMILY SSF54909 3 67 2.19E-7 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CWR56_RS12785 800d2a9b7f4f6a093c3decad7e157bba 103 Gene3D G3DSA:3.30.70.100 1 101 1.3E-7 T 29-03-2018 CWR56_RS00090 2ed30a294465ca3df0c2e394124c8e9d 207 SUPERFAMILY SSF52166 1 206 4.19E-82 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWR56_RS00090 2ed30a294465ca3df0c2e394124c8e9d 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 4.7E-73 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CWR56_RS00090 2ed30a294465ca3df0c2e394124c8e9d 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 6.6E-81 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00090 2ed30a294465ca3df0c2e394124c8e9d 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.383 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00090 2ed30a294465ca3df0c2e394124c8e9d 207 Gene3D G3DSA:3.40.1370.10 2 147 8.6E-61 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWR56_RS00090 2ed30a294465ca3df0c2e394124c8e9d 207 Gene3D G3DSA:3.40.1370.10 148 205 7.9E-16 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWR56_RS10755 2fed76bd67765415cfac3b2bca8a6708 76 Pfam PF12645 Helix-turn-helix domain 10 73 2.8E-23 T 29-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CWR56_RS01690 95d371ec8e7b05096c2df04f77a1b266 590 SUPERFAMILY SSF53300 400 582 7.87E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A CWR56_RS01690 95d371ec8e7b05096c2df04f77a1b266 590 Gene3D G3DSA:3.40.50.410 369 589 5.9E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A CWR56_RS01690 95d371ec8e7b05096c2df04f77a1b266 590 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 385 441 2.4E-4 T 29-03-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 PIRSF PIRSF019345 1 179 2.3E-53 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 169 3.7E-57 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 178 28.332 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 Gene3D G3DSA:1.10.10.10 1 86 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 SUPERFAMILY SSF46785 2 82 5.44E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 SUPERFAMILY SSF46785 86 160 7.62E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 174 2.5E-48 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR56_RS06010 cc50c47c5d6a696145af13694770209f 179 Gene3D G3DSA:1.10.10.10 87 177 1.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12940 12c5336778ec2a6d34d4a08151750dbe 547 Pfam PF13684 Dihydroxyacetone kinase family 235 547 3.4E-123 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CWR56_RS12940 12c5336778ec2a6d34d4a08151750dbe 547 Pfam PF02734 DAK2 domain 35 199 6.0E-42 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR56_RS12940 12c5336778ec2a6d34d4a08151750dbe 547 SMART SM01120 35 200 2.7E-66 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR56_RS12940 12c5336778ec2a6d34d4a08151750dbe 547 SUPERFAMILY SSF101473 5 201 1.83E-43 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR56_RS12940 12c5336778ec2a6d34d4a08151750dbe 547 SMART SM01121 235 547 8.3E-173 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CWR56_RS12940 12c5336778ec2a6d34d4a08151750dbe 547 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 10 547 4.3E-207 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 SUPERFAMILY SSF75217 69 244 3.14E-48 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 80 3.6E-20 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 SUPERFAMILY SSF55315 4 78 3.4E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 Pfam PF00588 SpoU rRNA Methylase family 98 237 7.1E-39 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 Gene3D G3DSA:3.40.1280.10 81 248 1.0E-45 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 SMART SM00967 6 81 3.7E-20 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 Gene3D G3DSA:3.30.1330.30 2 76 1.2E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CWR56_RS19005 4e02e8b0d5596bfdd07987b7a07c13ad 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 6 243 1.4E-80 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CWR56_RS07360 c6c47e9f8f71b996e145a9f88ddfbcf8 240 Pfam PF00977 Histidine biosynthesis protein 3 227 1.2E-78 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CWR56_RS07360 c6c47e9f8f71b996e145a9f88ddfbcf8 240 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 36.483 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CWR56_RS07360 c6c47e9f8f71b996e145a9f88ddfbcf8 240 SUPERFAMILY SSF51366 1 235 1.21E-74 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS07360 c6c47e9f8f71b996e145a9f88ddfbcf8 240 Gene3D G3DSA:3.20.20.70 2 237 4.6E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS07360 c6c47e9f8f71b996e145a9f88ddfbcf8 240 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 232 1.5E-88 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 Gene3D G3DSA:2.20.25.10 2 40 4.1E-17 T 29-03-2018 CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 Pfam PF08274 PhnA Zinc-Ribbon 4 32 1.3E-16 T 29-03-2018 IPR013987 PhnA protein, N-terminal CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 SUPERFAMILY SSF57783 3 34 1.43E-14 T 29-03-2018 CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 114 2.2E-43 T 29-03-2018 IPR004624 PhnA protein CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 SUPERFAMILY SSF82057 38 114 3.16E-26 T 29-03-2018 CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 Gene3D G3DSA:2.30.30.40 43 113 6.4E-34 T 29-03-2018 CWR56_RS18090 3836d520cdac3c714ea9bbf0c7e8e593 114 Pfam PF03831 PhnA domain 44 114 1.8E-32 T 29-03-2018 IPR013988 PhnA protein, C-terminal CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 Gene3D G3DSA:3.40.190.10 238 403 1.7E-35 T 29-03-2018 CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 249 511 2.5E-67 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 SUPERFAMILY SSF161098 16 201 1.7E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 197 4.9E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 SUPERFAMILY SSF53850 249 516 4.07E-74 T 29-03-2018 CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 Gene3D G3DSA:1.10.3720.10 14 210 2.3E-26 T 29-03-2018 CWR56_RS04430 d7c42a58a811f1c8c7d3b17c8b917588 517 Gene3D G3DSA:3.40.190.10 404 517 1.7E-21 T 29-03-2018 CWR56_RS02455 b45d312e592fc869524ffbe3a9e789fa 161 Pfam PF03975 CheD chemotactic sensory transduction 48 152 4.3E-33 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CWR56_RS02455 b45d312e592fc869524ffbe3a9e789fa 161 SUPERFAMILY SSF64438 4 157 1.19E-46 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CWR56_RS02455 b45d312e592fc869524ffbe3a9e789fa 161 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 157 27.294 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CWR56_RS04850 3adcbfc38dedefba75c19a493c87f28f 260 SMART SM00893 22 212 1.8E-59 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS04850 3adcbfc38dedefba75c19a493c87f28f 260 SUPERFAMILY SSF52402 1 256 3.77E-76 T 29-03-2018 CWR56_RS04850 3adcbfc38dedefba75c19a493c87f28f 260 Gene3D G3DSA:3.40.50.620 1 260 1.2E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS04850 3adcbfc38dedefba75c19a493c87f28f 260 Pfam PF01012 Electron transfer flavoprotein domain 22 207 1.5E-46 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS04850 3adcbfc38dedefba75c19a493c87f28f 260 PIRSF PIRSF000090 1 260 7.9E-91 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.4E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 Gene3D G3DSA:3.40.190.10 89 175 4.3E-12 T 29-03-2018 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 Gene3D G3DSA:3.40.190.10 176 265 1.1E-10 T 29-03-2018 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 Pfam PF03466 LysR substrate binding domain 90 289 1.5E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 Gene3D G3DSA:1.10.10.10 1 83 5.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 SUPERFAMILY SSF53850 89 295 1.39E-25 T 29-03-2018 CWR56_RS03450 cd220d048178988edcae723110c4b1ef 307 SUPERFAMILY SSF46785 1 84 3.38E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03380 6c36c74a2f8e06982570be73a9aae74e 866 Pfam PF12392 Collagenase 384 503 2.8E-25 T 29-03-2018 IPR020988 Peptidase U32, collagenase CWR56_RS03380 6c36c74a2f8e06982570be73a9aae74e 866 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR56_RS03380 6c36c74a2f8e06982570be73a9aae74e 866 Pfam PF01136 Peptidase family U32 76 299 2.4E-85 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR56_RS03380 6c36c74a2f8e06982570be73a9aae74e 866 Pfam PF01136 Peptidase family U32 660 854 2.4E-21 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR56_RS03380 6c36c74a2f8e06982570be73a9aae74e 866 Gene3D G3DSA:3.20.20.70 7 170 7.5E-13 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10355 e474e98c3e7714510d81df1843f2204b 209 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 202 9.8E-10 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWR56_RS10355 e474e98c3e7714510d81df1843f2204b 209 SUPERFAMILY SSF56219 1 207 4.97E-35 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWR56_RS10355 e474e98c3e7714510d81df1843f2204b 209 Gene3D G3DSA:3.60.10.10 1 206 1.2E-30 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWR56_RS05110 eb48f2af091941749038586e45e508db 882 ProSitePatterns PS00447 DNA polymerase family A signature. 708 727 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 733 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 745 756 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 609 631 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 829 842 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 654 677 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 778 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 799 815 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 632 647 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 684 697 2.9E-74 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SUPERFAMILY SSF47807 171 284 7.33E-34 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SUPERFAMILY SSF53098 302 472 1.08E-28 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Gene3D G3DSA:1.10.150.20 185 261 2.6E-29 T 29-03-2018 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SMART SM00279 173 208 2.4E-18 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Pfam PF00476 DNA polymerase family A 507 880 7.5E-158 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Gene3D G3DSA:1.20.1060.10 498 610 8.4E-34 T 29-03-2018 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SUPERFAMILY SSF56672 478 881 3.45E-157 T 29-03-2018 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Pfam PF01612 3'-5' exonuclease 356 443 2.2E-7 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SMART SM00475 3 261 2.0E-130 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SUPERFAMILY SSF88723 2 169 1.52E-53 T 29-03-2018 IPR029060 PIN domain-like CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Gene3D G3DSA:3.30.420.10 290 497 8.5E-20 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 169 1.1E-52 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Gene3D G3DSA:3.30.70.370 708 882 2.0E-48 T 29-03-2018 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Gene3D G3DSA:3.30.70.370 611 707 7.3E-21 T 29-03-2018 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Gene3D G3DSA:3.40.50.1010 3 184 9.7E-66 T 29-03-2018 IPR029060 PIN domain-like CWR56_RS05110 eb48f2af091941749038586e45e508db 882 SMART SM00482 640 846 1.3E-109 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 TIGRFAM TIGR00593 pola: DNA polymerase I 5 882 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR56_RS05110 eb48f2af091941749038586e45e508db 882 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 264 3.0E-31 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWR56_RS05030 31a491db71ad490fc7a11e64de443324 267 Hamap MF_00548 Zinc transporter ZupT [zupT]. 4 267 36.53 T 29-03-2018 IPR023498 Zinc transporter ZupT CWR56_RS05030 31a491db71ad490fc7a11e64de443324 267 Pfam PF02535 ZIP Zinc transporter 96 261 5.5E-31 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR56_RS00125 6f60b19752042e4a5dfd4929da883c0a 67 Gene3D G3DSA:1.10.287.310 1 65 2.0E-25 T 29-03-2018 CWR56_RS00125 6f60b19752042e4a5dfd4929da883c0a 67 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00125 6f60b19752042e4a5dfd4929da883c0a 67 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.245 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00125 6f60b19752042e4a5dfd4929da883c0a 67 SUPERFAMILY SSF46561 1 62 3.66E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00125 6f60b19752042e4a5dfd4929da883c0a 67 Pfam PF00831 Ribosomal L29 protein 4 60 1.2E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00125 6f60b19752042e4a5dfd4929da883c0a 67 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 3.2E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 Gene3D G3DSA:3.30.300.20 92 237 8.9E-8 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 Pfam PF00013 KH domain 205 263 1.1E-6 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 Hamap MF_00335 Ribonuclease Y [rny]. 5 513 25.329 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 SMART SM00322 201 268 9.3E-8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 SUPERFAMILY SSF109604 310 460 9.42E-31 T 29-03-2018 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 TIGRFAM TIGR00277 HDIG: HDIG domain 325 402 2.3E-22 T 29-03-2018 IPR006675 HDIG domain CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 513 5.4E-240 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 SUPERFAMILY SSF54791 201 297 5.32E-18 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 Pfam PF01966 HD domain 330 421 2.3E-18 T 29-03-2018 IPR006674 HD domain CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 Gene3D G3DSA:1.10.3210.10 238 452 1.2E-37 T 29-03-2018 CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 SMART SM00471 325 431 6.8E-14 T 29-03-2018 IPR003607 HD/PDEase domain CWR56_RS06180 807ae255ed0969be4d3e6cf179589b97 513 Pfam PF12072 Domain of unknown function (DUF3552) 7 198 2.9E-65 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 SUPERFAMILY SSF54211 252 266 1.02E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 SUPERFAMILY SSF54211 300 455 1.02E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 Gene3D G3DSA:3.40.50.300 54 256 4.4E-22 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 121 138 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 79 107 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 319 342 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 171 195 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 210 238 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 245 271 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 PRINTS PR01874 DNA repair protein radA signature 10 34 9.5E-90 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 Pfam PF13481 AAA domain 66 219 1.7E-14 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 43.925 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 342 427 6.6E-12 T 29-03-2018 CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 Gene3D G3DSA:3.30.230.10 257 457 2.4E-45 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 SMART SM00382 87 241 1.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 SUPERFAMILY SSF52540 56 266 3.05E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18860 e647c3ea92381e4bf8f4117b9c49ed8d 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 1.5E-191 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 Pfam PF13932 GidA associated domain 402 616 4.3E-78 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 624 40.962 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 1.7E-5 T 29-03-2018 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.7E-5 T 29-03-2018 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 SUPERFAMILY SSF51905 8 68 4.64E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 SUPERFAMILY SSF51905 99 262 4.64E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 621 6.2E-263 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 SMART SM01228 546 617 1.7E-39 T 29-03-2018 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 Gene3D G3DSA:3.50.50.60 7 266 4.8E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS18405 e17d35b0fe9c975874c284b284856e29 631 Pfam PF01134 Glucose inhibited division protein A 10 400 1.7E-159 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 29 353 9.5E-98 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 SUPERFAMILY SSF48029 25 146 1.83E-21 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 Pfam PF01706 FliG C-terminal domain 240 346 2.5E-35 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 Pfam PF14841 FliG middle domain 138 209 3.4E-24 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 Gene3D G3DSA:1.10.220.30 128 212 8.4E-18 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 Pfam PF14842 FliG N-terminal domain 29 129 5.6E-28 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 Gene3D G3DSA:1.10.220.30 7 108 4.6E-11 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 Gene3D G3DSA:1.10.220.30 217 355 5.2E-29 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PIRSF PIRSF003161 21 356 3.2E-99 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 SUPERFAMILY SSF48029 137 347 6.28E-59 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 248 268 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 56 82 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 217 242 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 294 320 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 136 159 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 270 290 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS01270 ec9c248743e2633232911e6ef39dc433 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 27 43 2.7E-54 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 SUPERFAMILY SSF53383 73 480 4.13E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 Gene3D G3DSA:1.10.10.10 3 79 2.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 SMART SM00345 18 77 4.9E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 Gene3D G3DSA:3.90.1150.10 381 482 9.7E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 SUPERFAMILY SSF46785 8 87 2.33E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 Gene3D G3DSA:3.40.640.10 136 380 4.6E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 6.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 Pfam PF00155 Aminotransferase class I and II 135 468 2.8E-23 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS06585 1f69488f30f9f555af249556827727c7 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS02940 0d25bd6213c1123e5f55e0f0c7c1e2d9 412 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 285 358 1.1E-23 T 29-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CWR56_RS02940 0d25bd6213c1123e5f55e0f0c7c1e2d9 412 Gene3D G3DSA:1.10.10.10 28 292 5.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02940 0d25bd6213c1123e5f55e0f0c7c1e2d9 412 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 286 357 1.3E-27 T 29-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CWR56_RS15115 2ef2f78a6ec69e08bc495e009eec8a74 424 Pfam PF00266 Aminotransferase class-V 28 414 1.8E-62 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS15115 2ef2f78a6ec69e08bc495e009eec8a74 424 SUPERFAMILY SSF53383 26 419 3.81E-70 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS15115 2ef2f78a6ec69e08bc495e009eec8a74 424 Gene3D G3DSA:3.90.1150.10 285 421 2.8E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS15115 2ef2f78a6ec69e08bc495e009eec8a74 424 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 219 239 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWR56_RS15115 2ef2f78a6ec69e08bc495e009eec8a74 424 Gene3D G3DSA:3.40.640.10 59 284 3.6E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS13285 7a9a3014258098d00e3a02bdedcf705c 491 Gene3D G3DSA:3.40.50.300 8 487 6.7E-14 T 29-03-2018 CWR56_RS13285 7a9a3014258098d00e3a02bdedcf705c 491 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 491 1.5E-219 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CWR56_RS13285 7a9a3014258098d00e3a02bdedcf705c 491 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 3 491 1.0E-216 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CWR56_RS13285 7a9a3014258098d00e3a02bdedcf705c 491 SUPERFAMILY SSF52540 17 261 3.53E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13285 7a9a3014258098d00e3a02bdedcf705c 491 PIRSF PIRSF007466 1 491 4.9E-222 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CWR56_RS05930 688578b61798464414fdabb638e99e92 146 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 3 122 1.3E-67 T 29-03-2018 IPR017787 NIF system FeS cluster assembly, NifU-like CWR56_RS05930 688578b61798464414fdabb638e99e92 146 Pfam PF01592 NifU-like N terminal domain 2 123 3.6E-50 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CWR56_RS05930 688578b61798464414fdabb638e99e92 146 SUPERFAMILY SSF82649 5 124 8.11E-47 T 29-03-2018 CWR56_RS05930 688578b61798464414fdabb638e99e92 146 Gene3D G3DSA:3.90.1010.10 1 144 1.5E-54 T 29-03-2018 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 Gene3D G3DSA:3.30.420.40 198 398 6.4E-82 T 29-03-2018 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 TIGRFAM TIGR00016 ackA: acetate kinase 1 397 1.6E-160 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PRINTS PR00471 Acetate kinase family signature 324 340 3.9E-45 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PRINTS PR00471 Acetate kinase family signature 3 14 3.9E-45 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PRINTS PR00471 Acetate kinase family signature 302 315 3.9E-45 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PRINTS PR00471 Acetate kinase family signature 175 188 3.9E-45 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PRINTS PR00471 Acetate kinase family signature 378 390 3.9E-45 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PRINTS PR00471 Acetate kinase family signature 205 226 3.9E-45 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 194.686 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 Gene3D G3DSA:3.30.420.40 2 197 8.4E-77 T 29-03-2018 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 PIRSF PIRSF000722 1 398 2.0E-154 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 SUPERFAMILY SSF53067 160 397 6.28E-94 T 29-03-2018 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 Pfam PF00871 Acetokinase family 2 391 9.2E-164 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR56_RS05345 f805ed1f106c2d437d9b1882d32ff97d 398 SUPERFAMILY SSF53067 1 198 1.08E-69 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 Gene3D G3DSA:3.40.50.720 164 329 2.0E-31 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 7.0E-50 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 SUPERFAMILY SSF51905 1 317 1.66E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 Gene3D G3DSA:3.50.50.60 1 163 6.1E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 451 5.7E-27 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 Gene3D G3DSA:3.30.390.30 330 459 2.9E-31 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PIRSF PIRSF000350 1 455 2.0E-90 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 SUPERFAMILY SSF55424 341 454 1.29E-31 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 316 4.6E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.9E-23 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 1.9E-23 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.9E-23 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 1.9E-23 T 29-03-2018 CWR56_RS15005 b7fbcbc2bb26b85a7dd1cf30efff2685 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 1.9E-23 T 29-03-2018 CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 Pfam PF01546 Peptidase family M20/M25/M40 88 449 7.3E-22 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 Pfam PF07687 Peptidase dimerisation domain 246 354 1.7E-5 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 Gene3D G3DSA:3.40.630.10 3 355 1.8E-35 T 29-03-2018 CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 SUPERFAMILY SSF55031 188 356 2.74E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 SUPERFAMILY SSF53187 369 454 3.43E-54 T 29-03-2018 CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 SUPERFAMILY SSF53187 8 188 3.43E-54 T 29-03-2018 CWR56_RS12585 cd3834bb8cd2db455cf4caed79d36f70 456 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 15 449 7.1E-99 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWR56_RS09095 f00fa398babd9bf664246f83a25933f5 233 Gene3D G3DSA:1.10.720.10 183 229 8.2E-5 T 29-03-2018 CWR56_RS09095 f00fa398babd9bf664246f83a25933f5 233 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 2 63 9.0E-11 T 29-03-2018 CWR56_RS09095 f00fa398babd9bf664246f83a25933f5 233 SMART SM00877 2 78 1.8E-30 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09095 f00fa398babd9bf664246f83a25933f5 233 SUPERFAMILY SSF143414 1 96 2.62E-27 T 29-03-2018 CWR56_RS09095 f00fa398babd9bf664246f83a25933f5 233 Pfam PF00936 BMC domain 3 77 9.9E-22 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS12670 9b912c5cb23b7b33607525dc3ed0dc4e 252 Gene3D G3DSA:1.10.10.60 197 247 0.0012 T 29-03-2018 CWR56_RS12670 9b912c5cb23b7b33607525dc3ed0dc4e 252 Gene3D G3DSA:1.10.10.60 117 196 1.2E-9 T 29-03-2018 CWR56_RS12670 9b912c5cb23b7b33607525dc3ed0dc4e 252 SMART SM00342 161 243 8.8E-12 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12670 9b912c5cb23b7b33607525dc3ed0dc4e 252 Pfam PF12833 Helix-turn-helix domain 168 240 5.8E-13 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS14590 ccfc1c2fb0b0a28be32355a1653262a9 91 Pfam PF08666 SAF domain 11 82 1.8E-11 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CWR56_RS14590 ccfc1c2fb0b0a28be32355a1653262a9 91 SMART SM00858 11 82 8.8E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CWR56_RS12170 d01d04cbf4c83767a130156c99af8780 280 Gene3D G3DSA:3.40.50.300 19 272 0.0018 T 29-03-2018 CWR56_RS12170 d01d04cbf4c83767a130156c99af8780 280 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 6 269 62.796 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CWR56_RS12170 d01d04cbf4c83767a130156c99af8780 280 Pfam PF03618 Kinase/pyrophosphorylase 8 264 7.2E-99 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CWR56_RS04720 e51092ed52ee1df97743f1bb04ff6ff9 324 Gene3D G3DSA:1.10.530.10 158 318 1.2E-36 T 29-03-2018 CWR56_RS04720 e51092ed52ee1df97743f1bb04ff6ff9 324 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 176 314 9.5E-23 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS04720 e51092ed52ee1df97743f1bb04ff6ff9 324 SMART SM00047 158 318 1.1E-27 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 SUPERFAMILY SSF53383 2 389 3.4E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 Gene3D G3DSA:3.40.640.10 68 278 1.1E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 160 184 2.3E-11 T 29-03-2018 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 91 111 2.3E-11 T 29-03-2018 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 226 250 2.3E-11 T 29-03-2018 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 113 134 2.3E-11 T 29-03-2018 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 Pfam PF00155 Aminotransferase class I and II 30 376 1.7E-66 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS00405 98232992057117e45c7d72fecf08f346 394 Gene3D G3DSA:3.90.1150.10 279 394 1.1E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS16405 7a36b1a6ebe376348e05eab0c8233189 274 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 7 270 1.3E-85 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CWR56_RS16405 7a36b1a6ebe376348e05eab0c8233189 274 SUPERFAMILY SSF161098 14 262 2.62E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS16405 7a36b1a6ebe376348e05eab0c8233189 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 270 1.1E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS16405 7a36b1a6ebe376348e05eab0c8233189 274 Gene3D G3DSA:1.10.3720.10 8 274 4.8E-44 T 29-03-2018 CWR56_RS14060 d492ca4f0dadda70ae37560742b1aaff 250 Gene3D G3DSA:3.90.550.10 4 217 7.9E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14060 d492ca4f0dadda70ae37560742b1aaff 250 SUPERFAMILY SSF53448 4 223 7.22E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14060 d492ca4f0dadda70ae37560742b1aaff 250 Pfam PF00535 Glycosyl transferase family 2 7 135 1.6E-35 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS02680 a73aa2e6102ab33457c887f8b162d33c 195 Gene3D G3DSA:1.10.10.60 9 51 5.9E-7 T 29-03-2018 CWR56_RS02680 a73aa2e6102ab33457c887f8b162d33c 195 SUPERFAMILY SSF46689 9 83 1.08E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02680 a73aa2e6102ab33457c887f8b162d33c 195 Gene3D G3DSA:1.10.10.60 52 195 1.2E-6 T 29-03-2018 CWR56_RS02680 a73aa2e6102ab33457c887f8b162d33c 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 66 3.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS12110 403a4e490619cc16c933e379ec3d0f05 69 Pfam PF11007 Spore coat associated protein JA (CotJA) 16 47 1.3E-12 T 29-03-2018 IPR020256 Spore coat protein CotJA CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 PIRSF PIRSF004846 1 270 6.1E-78 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 50 265 5.7E-65 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 Gene3D G3DSA:3.40.190.10 38 138 5.1E-16 T 29-03-2018 CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 SUPERFAMILY SSF53850 44 267 7.77E-64 T 29-03-2018 CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 Pfam PF13531 Bacterial extracellular solute-binding protein 45 266 7.6E-45 T 29-03-2018 CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 Gene3D G3DSA:3.40.190.10 139 215 7.4E-34 T 29-03-2018 CWR56_RS04270 0e5cd416806ae75d814e44c09178230e 270 Gene3D G3DSA:3.40.190.10 216 269 3.5E-6 T 29-03-2018 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PIRSF PIRSF016599 3 483 6.9E-182 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 Pfam PF07687 Peptidase dimerisation domain 213 286 2.7E-5 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 480 1.8E-184 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 Pfam PF01546 Peptidase family M20/M25/M40 74 478 3.3E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 250 269 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 426 442 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 136 153 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 207 224 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 81 100 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 160 178 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 102 120 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 PRINTS PR00934 X-His dipeptidase (M25) signature 448 470 7.1E-53 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 Gene3D G3DSA:3.40.630.10 11 483 3.8E-45 T 29-03-2018 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 SUPERFAMILY SSF53187 395 480 1.69E-57 T 29-03-2018 CWR56_RS03405 5eff4a898f14331c9440c8cc41c36add 483 SUPERFAMILY SSF53187 11 183 1.69E-57 T 29-03-2018 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 SUPERFAMILY SSF48452 86 200 7.05E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 SUPERFAMILY SSF48452 168 365 8.67E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Pfam PF00515 Tetratricopeptide repeat 334 366 5.9E-7 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Gene3D G3DSA:1.25.40.10 278 318 6.9E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Pfam PF13181 Tetratricopeptide repeat 268 298 0.034 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Pfam PF13181 Tetratricopeptide repeat 305 332 0.0067 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Gene3D G3DSA:1.25.40.10 319 376 2.4E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Gene3D G3DSA:1.25.40.10 52 138 0.0027 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Gene3D G3DSA:1.25.40.10 217 277 0.074 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 Gene3D G3DSA:1.25.40.10 139 216 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 SMART SM00028 300 333 0.018 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 SMART SM00028 266 299 0.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 SMART SM00028 334 366 0.019 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS03440 1c0e716c3bbeac040bdf21a14bcd7854 380 SMART SM00028 184 217 40.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS07785 1e4d62348476f9aad4c6f60ebd0ff89e 192 Gene3D G3DSA:2.60.60.30 19 187 4.5E-61 T 29-03-2018 CWR56_RS07785 1e4d62348476f9aad4c6f60ebd0ff89e 192 Pfam PF02342 TerD domain 1 188 4.7E-82 T 29-03-2018 IPR003325 TerD domain GO:0006950 CWR56_RS06170 9a0ca98882282913ddc3f7c5237b779e 180 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 174 1.1E-51 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CWR56_RS06170 9a0ca98882282913ddc3f7c5237b779e 180 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 69 1.7E-19 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWR56_RS06170 9a0ca98882282913ddc3f7c5237b779e 180 PIRSF PIRSF000847 1 180 6.2E-55 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CWR56_RS06170 9a0ca98882282913ddc3f7c5237b779e 180 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWR56_RS18895 dfa999df77913fc75083148877d5685d 457 Gene3D G3DSA:1.20.1250.20 232 446 7.2E-18 T 29-03-2018 CWR56_RS18895 dfa999df77913fc75083148877d5685d 457 SUPERFAMILY SSF103473 25 427 4.71E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS18895 dfa999df77913fc75083148877d5685d 457 Gene3D G3DSA:1.20.1250.20 23 231 2.2E-14 T 29-03-2018 CWR56_RS18895 dfa999df77913fc75083148877d5685d 457 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 22 457 6.6E-111 T 29-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CWR56_RS18895 dfa999df77913fc75083148877d5685d 457 Pfam PF13347 MFS/sugar transport protein 24 445 7.5E-97 T 29-03-2018 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 SMART SM00388 460 527 1.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 Gene3D G3DSA:1.10.287.130 450 521 3.3E-15 T 29-03-2018 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 SMART SM00387 573 680 3.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 SUPERFAMILY SSF47384 447 528 1.9E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 Gene3D G3DSA:3.30.565.10 522 670 3.7E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 574 665 1.2E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 661 1.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 613 1.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 638 1.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 Pfam PF00512 His Kinase A (phospho-acceptor) domain 460 526 6.4E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS11345 431c535679ca10612505d2ec35861d9e 689 SUPERFAMILY SSF55874 516 665 3.65E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 Pfam PF14804 Jag N-terminus 11 51 1.3E-14 T 29-03-2018 IPR032782 Jag, N-terminal CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 SUPERFAMILY SSF82708 154 205 5.49E-7 T 29-03-2018 IPR001374 R3H domain GO:0003676 CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 Pfam PF13083 KH domain 65 129 2.2E-12 T 29-03-2018 CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 Gene3D G3DSA:3.30.1370.50 144 209 1.3E-16 T 29-03-2018 IPR001374 R3H domain GO:0003676 CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 SMART SM00393 129 208 6.9E-18 T 29-03-2018 IPR001374 R3H domain GO:0003676 CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 Pfam PF01424 R3H domain 148 205 2.4E-14 T 29-03-2018 IPR001374 R3H domain GO:0003676 CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 SMART SM01245 7 59 1.3E-14 T 29-03-2018 IPR032782 Jag, N-terminal CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 Gene3D G3DSA:3.30.300.20 60 143 3.6E-19 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS18415 385b0650d65b71c082d7c4e98bd0b63c 209 Gene3D G3DSA:3.30.30.80 7 56 7.0E-17 T 29-03-2018 CWR56_RS02500 c5afbd71512330c2f1ef7c48fbc90ab7 329 SUPERFAMILY SSF51735 1 327 1.22E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS02500 c5afbd71512330c2f1ef7c48fbc90ab7 329 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 3 321 7.7E-80 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CWR56_RS02500 c5afbd71512330c2f1ef7c48fbc90ab7 329 Gene3D G3DSA:3.30.1780.10 1 135 5.3E-40 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CWR56_RS02500 c5afbd71512330c2f1ef7c48fbc90ab7 329 PIRSF PIRSF001439 1 329 1.5E-85 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CWR56_RS02500 c5afbd71512330c2f1ef7c48fbc90ab7 329 Gene3D G3DSA:3.40.50.720 136 302 3.0E-32 T 29-03-2018 CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 166 9.3E-29 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 268 413 6.7E-46 T 29-03-2018 IPR008136 CinA, C-terminal CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 PIRSF PIRSF006728 1 418 3.7E-157 T 29-03-2018 IPR008135 Competence-induced protein CinA CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 SMART SM00852 4 170 1.0E-43 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 418 166.509 T 29-03-2018 IPR008135 Competence-induced protein CinA CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 Gene3D G3DSA:3.40.980.10 1 171 1.4E-45 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 Pfam PF02464 Competence-damaged protein 262 412 2.4E-55 T 29-03-2018 IPR008136 CinA, C-terminal CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 SUPERFAMILY SSF142433 259 416 1.26E-53 T 29-03-2018 IPR008136 CinA, C-terminal CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 Gene3D G3DSA:3.90.950.20 254 418 5.2E-57 T 29-03-2018 CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 Pfam PF00994 Probable molybdopterin binding domain 4 169 4.6E-38 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 416 6.5E-124 T 29-03-2018 IPR008135 Competence-induced protein CinA CWR56_RS06595 e3e061d78bbea2404e5c797f3ddbf69d 418 SUPERFAMILY SSF53218 2 204 2.49E-41 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS12830 db4c9b31364d05f62a5b47d028927360 294 Pfam PF16138 Domain of unknown function (4846) 54 293 3.3E-105 T 29-03-2018 IPR032315 Protein of unknown function DUF4846 CWR56_RS04495 eed0509230d4554b29b52330d17c7410 163 TIGRFAM TIGR02084 leud: 3-isopropylmalate dehydratase, small subunit 5 159 3.4E-80 T 29-03-2018 IPR011824 Hydrolyase LeuD/DmdB, bacterial GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CWR56_RS04495 eed0509230d4554b29b52330d17c7410 163 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 163 37.663 T 29-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CWR56_RS04495 eed0509230d4554b29b52330d17c7410 163 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 4.8E-63 T 29-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CWR56_RS04495 eed0509230d4554b29b52330d17c7410 163 Gene3D G3DSA:3.20.19.10 2 162 9.9E-50 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR56_RS04495 eed0509230d4554b29b52330d17c7410 163 SUPERFAMILY SSF52016 4 160 6.87E-49 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR56_RS04495 eed0509230d4554b29b52330d17c7410 163 Pfam PF00694 Aconitase C-terminal domain 38 104 9.1E-18 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS12500 a5bb08d4a575a3df856b48b942f8063c 88 Pfam PF01649 Ribosomal protein S20 2 84 2.6E-23 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12500 a5bb08d4a575a3df856b48b942f8063c 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.955 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12500 a5bb08d4a575a3df856b48b942f8063c 88 SUPERFAMILY SSF46992 3 86 8.63E-25 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12500 a5bb08d4a575a3df856b48b942f8063c 88 Gene3D G3DSA:1.20.58.110 1 88 1.3E-23 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12500 a5bb08d4a575a3df856b48b942f8063c 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 16 80 3.0E-15 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS12500 a5bb08d4a575a3df856b48b942f8063c 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 3.8E-22 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS11135 46b5862b464058223605d5434e506a4e 152 Gene3D G3DSA:3.10.180.10 6 131 4.9E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS11135 46b5862b464058223605d5434e506a4e 152 SUPERFAMILY SSF54593 3 141 8.53E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS11135 46b5862b464058223605d5434e506a4e 152 Pfam PF12681 Glyoxalase-like domain 3 119 1.9E-37 T 29-03-2018 IPR025870 Glyoxalase-like domain CWR56_RS16080 772102145fc657381bec748044da9cbf 376 Gene3D G3DSA:3.30.565.10 215 376 1.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16080 772102145fc657381bec748044da9cbf 376 SUPERFAMILY SSF158472 83 132 1.83E-8 T 29-03-2018 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 SUPERFAMILY SSF55874 212 374 9.43E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16080 772102145fc657381bec748044da9cbf 376 SMART SM00387 267 376 1.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16080 772102145fc657381bec748044da9cbf 376 Gene3D G3DSA:1.10.287.130 142 214 1.6E-14 T 29-03-2018 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 374 3.8E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS16080 772102145fc657381bec748044da9cbf 376 Pfam PF00672 HAMP domain 84 131 2.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 7.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 7.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 355 7.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 SMART SM00304 82 134 1.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 SMART SM00388 156 221 8.6E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 SUPERFAMILY SSF47384 142 221 7.06E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS16080 772102145fc657381bec748044da9cbf 376 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 221 4.7E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS13250 6c5eb813c25f8c822cd88c1efab9cf41 152 Hamap MF_01197 Cell division protein SepF [sepF]. 3 141 16.638 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 CWR56_RS13250 6c5eb813c25f8c822cd88c1efab9cf41 152 Pfam PF04472 Cell division protein SepF 61 133 1.8E-25 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CWR56_RS09240 1ee4279b7e4c5de04948d345e01f47ec 248 Gene3D G3DSA:3.80.10.10 28 155 3.2E-4 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CWR56_RS09240 1ee4279b7e4c5de04948d345e01f47ec 248 Gene3D G3DSA:2.60.40.1080 156 248 2.0E-4 T 29-03-2018 CWR56_RS09085 624ae4afc71dbf0c9ec2592fcd222ba5 293 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 66 293 1.3E-81 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CWR56_RS09085 624ae4afc71dbf0c9ec2592fcd222ba5 293 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 57 293 40.515 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CWR56_RS09085 624ae4afc71dbf0c9ec2592fcd222ba5 293 PIRSF PIRSF018982 44 293 1.6E-104 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 SUPERFAMILY SSF51735 144 293 1.67E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 8.7E-36 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 SMART SM00829 14 350 3.3E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 Gene3D G3DSA:3.40.50.10730 153 302 2.3E-29 T 29-03-2018 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 Gene3D G3DSA:3.90.180.10 2 152 5.3E-50 T 29-03-2018 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 Gene3D G3DSA:3.90.180.10 303 352 0.041 T 29-03-2018 CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 SUPERFAMILY SSF50129 4 176 2.2E-53 T 29-03-2018 IPR011032 GroES-like CWR56_RS11290 65ed6d46c16fe0ebf411528752be583c 352 Pfam PF00107 Zinc-binding dehydrogenase 177 295 8.0E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR56_RS13455 cf06e084837d48efbfd6bd918a81809b 248 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 245 9.1E-64 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR56_RS13455 cf06e084837d48efbfd6bd918a81809b 248 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 236 1.2E-78 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR56_RS13455 cf06e084837d48efbfd6bd918a81809b 248 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 241 16.397 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR56_RS13455 cf06e084837d48efbfd6bd918a81809b 248 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 129 141 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR56_RS10390 4db576d552667ab2c6ebeb62bd8c2e66 458 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 2 456 2.1E-187 T 29-03-2018 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM CWR56_RS10390 4db576d552667ab2c6ebeb62bd8c2e66 458 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 262 367 4.9E-24 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS10390 4db576d552667ab2c6ebeb62bd8c2e66 458 SMART SM00876 262 369 1.0E-32 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS10390 4db576d552667ab2c6ebeb62bd8c2e66 458 Gene3D G3DSA:3.20.20.70 14 381 6.6E-65 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10390 4db576d552667ab2c6ebeb62bd8c2e66 458 SUPERFAMILY SSF102114 34 337 1.96E-46 T 29-03-2018 CWR56_RS17195 f95c143e42eaea2e75f23498d6192a29 387 SUPERFAMILY SSF53697 17 378 1.32E-52 T 29-03-2018 CWR56_RS17195 f95c143e42eaea2e75f23498d6192a29 387 Pfam PF01380 SIS domain 57 192 2.9E-10 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS17195 f95c143e42eaea2e75f23498d6192a29 387 Pfam PF01380 SIS domain 230 308 4.1E-6 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS17195 f95c143e42eaea2e75f23498d6192a29 387 Gene3D G3DSA:3.40.50.10490 5 214 2.1E-23 T 29-03-2018 CWR56_RS17195 f95c143e42eaea2e75f23498d6192a29 387 Gene3D G3DSA:3.40.50.10490 215 381 7.3E-17 T 29-03-2018 CWR56_RS09485 ef9193ff049661a217da97add7847307 183 Pfam PF17099 Tryptophan transporter TrpP 4 177 3.9E-55 T 29-03-2018 IPR031360 Tryptophan transporter TrpP CWR56_RS09485 ef9193ff049661a217da97add7847307 183 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 179 4.0E-42 T 29-03-2018 CWR56_RS04715 7a053073fe387d6d79a37db30adb9817 374 Gene3D G3DSA:3.40.50.2000 4 204 3.4E-76 T 29-03-2018 CWR56_RS04715 7a053073fe387d6d79a37db30adb9817 374 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 364 1.8E-119 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CWR56_RS04715 7a053073fe387d6d79a37db30adb9817 374 Gene3D G3DSA:3.40.50.2000 205 351 2.8E-33 T 29-03-2018 CWR56_RS04715 7a053073fe387d6d79a37db30adb9817 374 SUPERFAMILY SSF53756 4 369 8.9E-130 T 29-03-2018 CWR56_RS04715 7a053073fe387d6d79a37db30adb9817 374 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 366 8.9E-154 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 Pfam PF00561 alpha/beta hydrolase fold 45 321 2.0E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 SUPERFAMILY SSF53474 266 326 8.04E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 SUPERFAMILY SSF53474 22 159 8.04E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 47 55 2.3E-6 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 126 140 2.3E-6 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 75 86 2.3E-6 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CWR56_RS09570 116b90156036141da0d7c50809e5d19c 340 Gene3D G3DSA:3.40.50.1820 22 333 8.4E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Pfam PF00158 Sigma-54 interaction domain 126 291 1.1E-45 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 SUPERFAMILY SSF63520 487 582 1.27E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Pfam PF00874 PRD domain 513 582 3.8E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Pfam PF00874 PRD domain 759 846 4.8E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 SUPERFAMILY SSF53062 594 712 3.4E-17 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 SUPERFAMILY SSF63520 743 847 8.63E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Pfam PF03610 PTS system fructose IIA component 596 701 2.4E-11 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Gene3D G3DSA:3.40.50.510 582 733 9.5E-27 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 SUPERFAMILY SSF52540 125 363 1.17E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Gene3D G3DSA:1.10.1790.10 750 850 2.7E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 SMART SM00382 148 299 1.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Gene3D G3DSA:1.10.10.10 1 79 1.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Gene3D G3DSA:1.10.1790.10 458 581 2.3E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01450 9ed318ab011a970dcf53437e9edde3d8 855 Gene3D G3DSA:3.40.50.300 95 447 1.9E-23 T 29-03-2018 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 SUPERFAMILY SSF46689 177 228 1.15E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 Gene3D G3DSA:2.60.120.280 4 165 6.6E-17 T 29-03-2018 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 Gene3D G3DSA:1.10.10.60 176 231 2.4E-13 T 29-03-2018 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 231 272 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 SUPERFAMILY SSF46689 231 278 1.25E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 Pfam PF12833 Helix-turn-helix domain 202 277 2.3E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 276 9.5E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 260 9.5E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 Gene3D G3DSA:1.10.10.60 234 279 5.2E-10 T 29-03-2018 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 SUPERFAMILY SSF51215 21 160 1.7E-13 T 29-03-2018 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 Pfam PF02311 AraC-like ligand binding domain 21 154 2.1E-8 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWR56_RS13485 5447f300e19a56fd6e659710e3322f77 289 SMART SM00342 194 276 5.3E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS14605 aa2ab351a86d383d532f3fe74f324a35 446 Pfam PF01554 MatE 250 406 1.8E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS14605 aa2ab351a86d383d532f3fe74f324a35 446 Pfam PF01554 MatE 22 185 6.6E-31 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS14605 aa2ab351a86d383d532f3fe74f324a35 446 PIRSF PIRSF006603 1 446 3.5E-93 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS14605 aa2ab351a86d383d532f3fe74f324a35 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 419 8.1E-64 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS16595 7416807cc1063f181d71afb9ffd8155f 203 Pfam PF01926 50S ribosome-binding GTPase 25 143 4.9E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS16595 7416807cc1063f181d71afb9ffd8155f 203 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.623 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CWR56_RS16595 7416807cc1063f181d71afb9ffd8155f 203 Gene3D G3DSA:3.40.50.300 2 200 7.6E-35 T 29-03-2018 CWR56_RS16595 7416807cc1063f181d71afb9ffd8155f 203 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 5.9E-74 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CWR56_RS16595 7416807cc1063f181d71afb9ffd8155f 203 SUPERFAMILY SSF52540 1 193 8.24E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 SUPERFAMILY SSF116726 215 289 1.83E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 SUPERFAMILY SSF81340 6 205 6.67E-47 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 Pfam PF00654 Voltage gated chloride channel 6 188 9.5E-40 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 Gene3D G3DSA:3.30.70.1450 213 293 1.1E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 Gene3D G3DSA:1.10.3080.10 3 212 1.6E-39 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 PRINTS PR00762 Chloride channel signature 139 155 1.3E-9 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 PRINTS PR00762 Chloride channel signature 104 124 1.3E-9 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 PRINTS PR00762 Chloride channel signature 157 176 1.3E-9 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS02850 edd266432f2d4e5a3da51c3143b3982e 300 Pfam PF02080 TrkA-C domain 223 280 2.1E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS00165 640a024e75f0579c01f5eb054aeeeca5 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 122 1.6E-49 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00165 640a024e75f0579c01f5eb054aeeeca5 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 122 3.3E-46 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00165 640a024e75f0579c01f5eb054aeeeca5 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 122 29.583 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00165 640a024e75f0579c01f5eb054aeeeca5 122 Gene3D G3DSA:3.30.420.100 1 122 9.8E-45 T 29-03-2018 CWR56_RS00165 640a024e75f0579c01f5eb054aeeeca5 122 SUPERFAMILY SSF53137 7 120 2.43E-55 T 29-03-2018 CWR56_RS03170 8eabe2470cef3dde7435ee28d0078a5d 245 Pfam PF12730 ABC-2 family transporter protein 9 180 1.7E-22 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS07810 28c19dc65fc4d98cc35a6d45a2f56708 358 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 345 6.0E-95 T 29-03-2018 CWR56_RS07810 28c19dc65fc4d98cc35a6d45a2f56708 358 SUPERFAMILY SSF51621 34 289 6.43E-17 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR56_RS07810 28c19dc65fc4d98cc35a6d45a2f56708 358 PIRSF PIRSF015582 14 354 1.1E-44 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CWR56_RS07810 28c19dc65fc4d98cc35a6d45a2f56708 358 Gene3D G3DSA:3.20.20.360 21 316 6.4E-27 T 29-03-2018 CWR56_RS12355 a4da384dc19857785f67ea797b94c491 147 Pfam PF09424 Yqey-like protein 4 146 5.5E-54 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CWR56_RS12355 a4da384dc19857785f67ea797b94c491 147 Gene3D G3DSA:1.10.10.410 91 147 3.0E-20 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CWR56_RS12355 a4da384dc19857785f67ea797b94c491 147 SUPERFAMILY SSF89095 1 146 9.42E-43 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CWR56_RS12355 a4da384dc19857785f67ea797b94c491 147 Gene3D G3DSA:1.10.1510.10 1 90 4.0E-28 T 29-03-2018 CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 Gene3D G3DSA:3.30.70.20 19 74 1.1E-10 T 29-03-2018 CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 94 105 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 SUPERFAMILY SSF54862 4 144 3.65E-36 T 29-03-2018 CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 Pfam PF13247 4Fe-4S dicluster domain 57 146 1.7E-18 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 Gene3D G3DSA:3.30.70.20 1 18 0.0018 T 29-03-2018 CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 Gene3D G3DSA:3.30.70.20 75 114 1.3E-15 T 29-03-2018 CWR56_RS00865 7ac2d3d57e68949e34f99dd343544834 157 Gene3D G3DSA:3.30.70.20 115 152 1.6E-4 T 29-03-2018 CWR56_RS07875 6e4a3591356dc6fe9a010c86e1990afb 265 SUPERFAMILY SSF53850 30 265 9.31E-68 T 29-03-2018 CWR56_RS07875 6e4a3591356dc6fe9a010c86e1990afb 265 Pfam PF03180 NLPA lipoprotein 31 265 6.6E-73 T 29-03-2018 IPR004872 Lipoprotein NlpA family CWR56_RS07875 6e4a3591356dc6fe9a010c86e1990afb 265 PIRSF PIRSF002854 1 265 3.2E-79 T 29-03-2018 IPR004872 Lipoprotein NlpA family CWR56_RS07875 6e4a3591356dc6fe9a010c86e1990afb 265 Gene3D G3DSA:3.40.190.10 123 265 6.6E-40 T 29-03-2018 CWR56_RS07875 6e4a3591356dc6fe9a010c86e1990afb 265 Gene3D G3DSA:3.40.190.10 21 122 6.3E-20 T 29-03-2018 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 295 36.001 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 210 8.2E-76 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 Gene3D G3DSA:3.30.160.40 219 296 6.3E-15 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 PIRSF PIRSF001438 1 299 1.1E-109 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 SUPERFAMILY SSF53850 2 215 2.5E-76 T 29-03-2018 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 293 3.3E-13 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 295 8.0E-106 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 SUPERFAMILY SSF54782 219 296 1.7E-19 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 Gene3D G3DSA:3.40.190.10 104 197 6.4E-34 T 29-03-2018 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 Gene3D G3DSA:3.40.190.10 1 103 6.2E-43 T 29-03-2018 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 4.3E-37 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 4.3E-37 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 4.3E-37 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 PRINTS PR00151 Porphobilinogen deaminase signature 73 92 4.3E-37 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS17045 cabbad53855cc4caab5a5f3916541016 301 PRINTS PR00151 Porphobilinogen deaminase signature 42 62 4.3E-37 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 22 46 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 192 217 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 162 188 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 353 371 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 312 337 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 221 242 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 126 152 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PRINTS PR00083 Histidinol dehydrogenase signature 243 262 1.7E-75 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 221 253 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 Gene3D G3DSA:3.40.50.1980 218 363 4.9E-65 T 29-03-2018 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 PIRSF PIRSF000099 1 421 4.9E-145 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 SUPERFAMILY SSF53720 20 419 3.14E-71 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 22 418 9.4E-156 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 419 36.54 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 Gene3D G3DSA:3.40.50.1980 15 217 4.7E-79 T 29-03-2018 CWR56_RS07495 a30a91196464ac65d61636b130250a1b 421 Pfam PF00815 Histidinol dehydrogenase 11 419 1.8E-155 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CWR56_RS07835 0fae8aa57c9c3c6462d83a1c4760d5f5 400 Pfam PF05684 Protein of unknown function (DUF819) 16 399 7.2E-98 T 29-03-2018 IPR008537 Protein of unknown function DUF819 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 Gene3D G3DSA:2.40.50.100 75 105 0.19 T 29-03-2018 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 Pfam PF00364 Biotin-requiring enzyme 75 147 5.3E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 104 121 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 SUPERFAMILY SSF51230 71 147 1.7E-22 T 29-03-2018 IPR011053 Single hybrid motif CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 Gene3D G3DSA:2.40.50.100 106 149 6.3E-17 T 29-03-2018 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 148 1.4E-42 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 77 90 1.7E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 94 108 1.7E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR56_RS09225 0b7ad47111f6f33c1133cd75d70fd8e5 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 109 122 1.7E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 Gene3D G3DSA:3.30.160.70 2 77 1.1E-11 T 29-03-2018 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 SUPERFAMILY SSF53155 3 86 1.29E-13 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 132 138 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 82 161 5.2E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 83 162 5.4E-25 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 Gene3D G3DSA:1.10.10.10 78 164 1.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 SUPERFAMILY SSF46767 81 162 1.28E-24 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS08520 dbdf9b6ae290e6f9dc41d0bc3df348df 164 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 75 1.6E-4 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 Gene3D G3DSA:1.10.10.10 1 102 1.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 Pfam PF01022 Bacterial regulatory protein, arsR family 28 76 1.3E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 SUPERFAMILY SSF46785 17 92 3.75E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 5.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 5.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 5.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS15600 2de35973c4567778984a9e24d900c018 121 SMART SM00418 21 107 9.0E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 265 28.532 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 SUPERFAMILY SSF51735 2 158 3.74E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 98 7.4E-18 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 4.0E-40 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 Gene3D G3DSA:3.40.50.720 1 158 2.2E-30 T 29-03-2018 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 Gene3D G3DSA:1.10.3730.10 159 267 1.0E-44 T 29-03-2018 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 PIRSF PIRSF000193 1 267 5.3E-89 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 SUPERFAMILY SSF48179 161 267 2.72E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 264 6.7E-90 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS16500 d474cce288bd1425fed081c2e37cc763 267 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 221 243 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SMART SM00267 699 869 1.4E-46 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SUPERFAMILY SSF55785 338 442 1.22E-18 T 29-03-2018 IPR000014 PAS domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.450.20 453 575 3.0E-16 T 29-03-2018 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.450.20 313 452 2.4E-20 T 29-03-2018 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.450.20 576 712 6.5E-22 T 29-03-2018 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.450.20 155 275 3.3E-20 T 29-03-2018 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SUPERFAMILY SSF55781 898 1055 4.58E-12 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.70.270 713 872 4.2E-50 T 29-03-2018 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Pfam PF02743 Cache domain 57 271 9.4E-19 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 467 577 6.9E-12 T 29-03-2018 IPR000014 PAS domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 337 447 1.9E-17 T 29-03-2018 IPR000014 PAS domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Pfam PF08447 PAS fold 629 691 6.1E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Pfam PF08447 PAS fold 347 433 4.4E-17 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Pfam PF08447 PAS fold 477 559 6.6E-10 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Pfam PF00990 Diguanylate cyclase, GGDEF domain 711 864 4.9E-40 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.450.20 53 154 1.2E-10 T 29-03-2018 CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SUPERFAMILY SSF55785 567 696 2.09E-12 T 29-03-2018 IPR000014 PAS domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SUPERFAMILY SSF55785 437 568 8.03E-15 T 29-03-2018 IPR000014 PAS domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 Gene3D G3DSA:3.30.450.40 895 1053 4.5E-12 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SMART SM00086 399 440 1.6E-9 T 29-03-2018 IPR001610 PAC motif CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SMART SM00086 657 699 0.024 T 29-03-2018 IPR001610 PAC motif CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SMART SM00086 529 570 0.013 T 29-03-2018 IPR001610 PAC motif CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 707 867 8.5E-37 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04530 e9bef4ce41452899479de046ca1216d8 1182 SUPERFAMILY SSF55073 715 871 7.85E-42 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS12330 7ba99f17f19007e21da49dc5e01dbc27 338 Pfam PF02562 PhoH-like protein 109 312 2.9E-96 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CWR56_RS12330 7ba99f17f19007e21da49dc5e01dbc27 338 Gene3D G3DSA:3.40.50.300 106 312 9.4E-31 T 29-03-2018 CWR56_RS12330 7ba99f17f19007e21da49dc5e01dbc27 338 SUPERFAMILY SSF52540 36 70 6.75E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12330 7ba99f17f19007e21da49dc5e01dbc27 338 SUPERFAMILY SSF52540 108 287 6.75E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 206 6.2E-58 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 SUPERFAMILY SSF56037 373 457 3.92E-19 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 Gene3D G3DSA:3.50.40.10 350 457 5.2E-13 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 387 430 7.9E-17 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 SUPERFAMILY SSF52402 2 211 1.83E-57 T 29-03-2018 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 SMART SM00977 387 457 2.4E-23 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 Pfam PF11734 TilS substrate C-terminal domain 388 454 6.8E-13 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 3 317 24.204 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 SUPERFAMILY SSF82829 215 322 2.62E-16 T 29-03-2018 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 Pfam PF01171 PP-loop family 21 201 3.5E-51 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CWR56_RS17775 379ecd41f7469302dda36688fe66c228 462 Gene3D G3DSA:3.40.50.620 17 255 1.4E-41 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 424 48.404 T 29-03-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 Gene3D G3DSA:3.40.1060.10 150 276 7.5E-47 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 TIGRFAM TIGR02083 LEU2: 3-isopropylmalate dehydratase, large subunit 3 424 2.5E-217 T 29-03-2018 IPR011823 3-isopropylmalate dehydratase, large subunit, bacteria GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 Gene3D G3DSA:3.30.499.10 277 425 6.5E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 Gene3D G3DSA:3.30.499.10 1 149 1.1E-36 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 ProSitePatterns PS01244 Aconitase family signature 2. 357 370 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 114 127 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 128 143 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 190 203 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 103 111 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 301 312 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 204 217 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 PRINTS PR00415 Aconitase family signature 357 370 6.3E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 SUPERFAMILY SSF53732 1 423 1.83E-141 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 Pfam PF00330 Aconitase family (aconitate hydratase) 8 416 4.2E-100 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 ProSitePatterns PS00450 Aconitase family signature 1. 297 313 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 421 2.3E-167 T 29-03-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 CWR56_RS04490 9f0165f4c95801b617b08438fe6ceed9 425 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 422 4.4E-155 T 29-03-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWR56_RS08170 dec740e483430b1fd27851c152dd8b03 464 Pfam PF03606 C4-dicarboxylate anaerobic carrier 11 459 2.5E-124 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 10 98 2.7E-28 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 SUPERFAMILY SSF51690 100 265 7.85E-58 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 100 265 3.7E-60 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 2 265 8.1E-101 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 Gene3D G3DSA:3.90.1170.20 1 125 4.0E-39 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 Gene3D G3DSA:3.20.20.70 126 256 5.4E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 PIRSF PIRSF006250 1 269 5.1E-95 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CWR56_RS11780 24b99659b97cbe491bbf496d980a2cba 270 SUPERFAMILY SSF54675 2 99 5.89E-27 T 29-03-2018 CWR56_RS17415 c42604a689ef5586679a8168f1a5ac6d 94 Gene3D G3DSA:1.20.5.990 33 86 3.7E-4 T 29-03-2018 CWR56_RS17415 c42604a689ef5586679a8168f1a5ac6d 94 Pfam PF04977 Septum formation initiator 24 93 6.1E-11 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CWR56_RS02740 9453377c028463f7999a53ec6c2b7d84 831 SUPERFAMILY SSF52540 28 162 2.89E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02740 9453377c028463f7999a53ec6c2b7d84 831 Gene3D G3DSA:3.40.50.300 2 43 2.6E-4 T 29-03-2018 CWR56_RS02740 9453377c028463f7999a53ec6c2b7d84 831 Gene3D G3DSA:3.40.50.300 44 290 5.0E-9 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.3E-35 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.3E-35 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.3E-35 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 3.3E-35 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 3.3E-35 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 Gene3D G3DSA:3.40.50.720 144 313 1.9E-26 T 29-03-2018 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 298 4.7E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 SUPERFAMILY SSF51905 2 308 3.76E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 1.4E-69 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 5 309 4.1E-111 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CWR56_RS11700 3d75510d158a43369121d474f2872169 315 Gene3D G3DSA:3.50.50.60 1 143 5.8E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SMART SM00028 401 434 51.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SMART SM00028 326 359 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SMART SM00028 363 396 5.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SMART SM00028 71 104 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SMART SM00028 105 138 68.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Gene3D G3DSA:1.20.58.280 314 341 0.12 T 29-03-2018 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Pfam PF13174 Tetratricopeptide repeat 402 434 0.0019 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Gene3D G3DSA:1.25.40.10 342 447 6.1E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SUPERFAMILY SSF48452 324 436 3.34E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Gene3D G3DSA:1.20.5.1070 217 313 1.7E-4 T 29-03-2018 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SUPERFAMILY SSF48452 172 224 5.22E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 SUPERFAMILY SSF48452 75 141 5.22E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Pfam PF13181 Tetratricopeptide repeat 364 391 0.0036 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Gene3D G3DSA:1.25.40.10 154 216 0.0033 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS06760 0a807b72f1fcb4cf5c32003cf776b8b6 448 Gene3D G3DSA:1.25.40.10 64 150 1.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS13545 4dbdf6a6ccb0104f5647726be941fc17 221 Pfam PF01144 Coenzyme A transferase 8 202 2.1E-37 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CWR56_RS13545 4dbdf6a6ccb0104f5647726be941fc17 221 SUPERFAMILY SSF100950 5 214 6.28E-68 T 29-03-2018 CWR56_RS13545 4dbdf6a6ccb0104f5647726be941fc17 221 SMART SM00882 8 203 1.3E-64 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CWR56_RS13545 4dbdf6a6ccb0104f5647726be941fc17 221 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 209 6.2E-90 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CWR56_RS13545 4dbdf6a6ccb0104f5647726be941fc17 221 Gene3D G3DSA:3.40.1080.10 5 215 4.2E-65 T 29-03-2018 CWR56_RS13545 4dbdf6a6ccb0104f5647726be941fc17 221 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 46 54 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CWR56_RS03555 1d66d70876dd70356d90b2d7b8124208 63 Pfam PF10133 Predicted RNA-binding protein 1 61 1.8E-23 T 29-03-2018 IPR019300 RNA-binding protein, predicted CWR56_RS16855 5c855013a17b4b1489cabc3d361ebcc5 296 Gene3D G3DSA:2.10.270.10 17 286 9.1E-4 T 29-03-2018 CWR56_RS16855 5c855013a17b4b1489cabc3d361ebcc5 296 SUPERFAMILY SSF54001 153 258 4.63E-9 T 29-03-2018 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 SUPERFAMILY SSF51735 2 167 1.68E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 PIRSF PIRSF000149 1 335 2.6E-124 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 325 3.4E-136 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 SMART SM00846 2 151 2.8E-93 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 5.7E-64 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 Gene3D G3DSA:3.40.50.720 1 160 1.0E-77 T 29-03-2018 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 1.0E-33 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.0E-33 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 1.0E-33 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 1.0E-33 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 1.0E-33 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 SUPERFAMILY SSF55347 151 314 4.76E-66 T 29-03-2018 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 103 5.1E-41 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15935 90d5f2f2f11a63d06f688a7c5b152204 335 Gene3D G3DSA:3.30.360.10 161 315 1.4E-61 T 29-03-2018 CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 Pfam PF00072 Response regulator receiver domain 4 112 3.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 SUPERFAMILY SSF52172 3 173 3.84E-37 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 SMART SM00448 2 111 5.3E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 Gene3D G3DSA:1.10.10.10 125 230 8.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 SMART SM00862 151 227 1.5E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 Gene3D G3DSA:3.40.50.2300 2 124 2.1E-34 T 29-03-2018 CWR56_RS02215 48ecaeb8e6f98be494828bdc4bb9a83c 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 8.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS05895 afb32c94173ae21d225028e43a7de5a7 369 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 75 291 5.0E-76 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CWR56_RS05895 afb32c94173ae21d225028e43a7de5a7 369 Pfam PF02481 DNA recombination-mediator protein A 76 283 1.1E-76 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CWR56_RS05895 afb32c94173ae21d225028e43a7de5a7 369 SUPERFAMILY SSF102405 84 291 1.28E-33 T 29-03-2018 CWR56_RS05895 afb32c94173ae21d225028e43a7de5a7 369 Gene3D G3DSA:1.10.10.10 280 362 3.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05895 afb32c94173ae21d225028e43a7de5a7 369 Gene3D G3DSA:3.40.50.450 117 264 1.5E-29 T 29-03-2018 CWR56_RS03255 ccc6d92e5a2956a57053fb718a37e6ad 470 Gene3D G3DSA:3.10.450.50 336 467 2.3E-16 T 29-03-2018 CWR56_RS03255 ccc6d92e5a2956a57053fb718a37e6ad 470 SUPERFAMILY SSF54427 335 464 1.26E-21 T 29-03-2018 IPR032710 NTF2-like domain CWR56_RS03255 ccc6d92e5a2956a57053fb718a37e6ad 470 Pfam PF07366 SnoaL-like polyketide cyclase 334 463 3.3E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWR56_RS03255 ccc6d92e5a2956a57053fb718a37e6ad 470 Gene3D G3DSA:3.10.450.50 156 284 1.6E-7 T 29-03-2018 CWR56_RS03255 ccc6d92e5a2956a57053fb718a37e6ad 470 SUPERFAMILY SSF54427 149 291 1.75E-21 T 29-03-2018 IPR032710 NTF2-like domain CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 Gene3D G3DSA:1.10.10.10 134 237 2.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 235 5.2E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 Pfam PF00072 Response regulator receiver domain 6 115 1.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 SMART SM00448 4 114 1.3E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 Gene3D G3DSA:3.40.50.2300 1 133 4.7E-33 T 29-03-2018 CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 SUPERFAMILY SSF46894 136 235 2.69E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 SUPERFAMILY SSF52172 2 127 1.38E-38 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS13000 cab039ca5e2ebe6ec35751d2b9b2c9cf 238 SMART SM00862 160 235 1.5E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 SUPERFAMILY SSF46785 3 112 2.32E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 SUPERFAMILY SSF53850 93 292 3.56E-34 T 29-03-2018 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 Pfam PF03466 LysR substrate binding domain 93 292 6.9E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 Gene3D G3DSA:1.10.10.10 1 85 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 Gene3D G3DSA:3.40.190.10 92 182 2.4E-15 T 29-03-2018 CWR56_RS09295 37c49de885424f7bbfab592710c47d23 295 Gene3D G3DSA:3.40.190.10 183 267 3.3E-9 T 29-03-2018 CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 SMART SM00640 35 453 1.9E-111 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 SUPERFAMILY SSF49899 337 476 2.85E-25 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 Gene3D G3DSA:2.60.120.560 360 489 2.9E-19 T 29-03-2018 CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 35 337 3.0E-95 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 SUPERFAMILY SSF75005 25 338 1.57E-103 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 Gene3D G3DSA:2.115.10.20 40 359 3.4E-90 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 343 476 2.3E-18 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 35 48 - T 29-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWR56_RS08700 4610bd76d23f5e4b61ccbf17ff13ef1d 493 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 20 463 1.9E-151 T 29-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 SUPERFAMILY SSF52540 68 352 8.78E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 SMART SM00490 253 334 2.2E-32 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 Gene3D G3DSA:3.40.50.300 1 219 5.5E-57 T 29-03-2018 CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 Pfam PF00270 DEAD/DEAH box helicase 25 191 2.9E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 Gene3D G3DSA:3.40.50.300 220 368 4.6E-44 T 29-03-2018 CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 Pfam PF00271 Helicase conserved C-terminal domain 226 334 4.7E-30 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS04070 7a33e2311af4ecfd104ad97183f3a4f1 369 SMART SM00487 20 217 1.2E-58 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 Gene3D G3DSA:3.40.50.300 17 183 3.5E-34 T 29-03-2018 CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 Pfam PF01926 50S ribosome-binding GTPase 126 200 1.9E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 127 147 4.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 173 188 4.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 PIRSF PIRSF006230 3 287 5.6E-98 T 29-03-2018 IPR016478 GTPase, MTG1 CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 Gene3D G3DSA:1.10.1580.10 184 276 9.9E-23 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 SUPERFAMILY SSF52540 13 260 3.74E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05820 12ebef1acd97d78346cc704952fb1b0e 289 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 7 282 7.9E-110 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 Gene3D G3DSA:3.40.50.300 1 242 1.4E-74 T 29-03-2018 CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 323 3.4E-115 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 Pfam PF08402 TOBE domain 274 341 2.3E-5 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 SUPERFAMILY SSF50331 238 342 1.53E-12 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 SMART SM00382 30 213 3.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 Pfam PF00005 ABC transporter 21 163 1.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04670 31fc817a49985c9af355a3d5eff01f63 347 SUPERFAMILY SSF52540 5 243 1.39E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00760 35c480ce83463af51cadddedb18f45cd 155 Pfam PF12681 Glyoxalase-like domain 3 123 4.6E-38 T 29-03-2018 IPR025870 Glyoxalase-like domain CWR56_RS00760 35c480ce83463af51cadddedb18f45cd 155 Gene3D G3DSA:3.10.180.10 1 129 1.2E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS00760 35c480ce83463af51cadddedb18f45cd 155 SUPERFAMILY SSF54593 1 120 1.09E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 SMART SM00448 9 120 5.2E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 SUPERFAMILY SSF52172 5 132 2.56E-36 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 2.9E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 Pfam PF00072 Response regulator receiver domain 11 119 1.3E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 Gene3D G3DSA:3.40.50.2300 3 128 2.0E-31 T 29-03-2018 CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 SUPERFAMILY SSF46894 144 235 1.36E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 Gene3D G3DSA:1.10.10.10 130 237 1.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03185 5c891aa06fd2e37f5dea0244cebf7936 237 SMART SM00862 158 234 1.2E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14205 731caa4840323c39f6466cb291e6fe81 47 Pfam PF13165 Six-cysteine peptide SCIFF 4 46 1.5E-23 T 29-03-2018 IPR023975 Six-cysteine peptide SCIFF CWR56_RS14205 731caa4840323c39f6466cb291e6fe81 47 TIGRFAM TIGR03973 six_Cys_in_45: six-cysteine peptide SCIFF 4 46 9.1E-24 T 29-03-2018 IPR023975 Six-cysteine peptide SCIFF CWR56_RS11495 60469e7b93982f2ccd9eecc89551bb3d 231 Pfam PF00005 ABC transporter 17 158 2.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS11495 60469e7b93982f2ccd9eecc89551bb3d 231 Gene3D G3DSA:3.40.50.300 1 230 1.0E-53 T 29-03-2018 CWR56_RS11495 60469e7b93982f2ccd9eecc89551bb3d 231 SUPERFAMILY SSF52540 1 229 1.12E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11495 60469e7b93982f2ccd9eecc89551bb3d 231 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS11495 60469e7b93982f2ccd9eecc89551bb3d 231 SMART SM00382 25 210 1.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02715 0eb81c0397983eb98e8adf83c70da6ab 392 SUPERFAMILY SSF55073 250 389 2.59E-33 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS02715 0eb81c0397983eb98e8adf83c70da6ab 392 SMART SM00267 234 391 6.9E-25 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02715 0eb81c0397983eb98e8adf83c70da6ab 392 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 241 389 7.4E-29 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02715 0eb81c0397983eb98e8adf83c70da6ab 392 Gene3D G3DSA:3.30.70.270 238 391 1.2E-33 T 29-03-2018 CWR56_RS02715 0eb81c0397983eb98e8adf83c70da6ab 392 Pfam PF00990 Diguanylate cyclase, GGDEF domain 245 388 2.1E-29 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14855 2637f4ce991efea00b39bf83c98c60df 284 Pfam PF02673 Bacitracin resistance protein BacA 13 272 3.6E-77 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR56_RS14855 2637f4ce991efea00b39bf83c98c60df 284 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 7 277 16.923 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR56_RS14855 2637f4ce991efea00b39bf83c98c60df 284 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 13 270 6.4E-72 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR56_RS15965 1be4c6213536770e243f101a539517a5 450 Pfam PF00860 Permease family 21 401 8.3E-97 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS15965 1be4c6213536770e243f101a539517a5 450 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 15 431 4.7E-107 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR56_RS15965 1be4c6213536770e243f101a539517a5 450 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 349 369 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR56_RS15965 1be4c6213536770e243f101a539517a5 450 TIGRFAM TIGR03173 pbuX: xanthine permease 25 434 5.3E-145 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 Pfam PF00072 Response regulator receiver domain 4 111 1.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 SUPERFAMILY SSF52172 2 172 2.7E-38 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 SMART SM00448 2 111 6.2E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 Gene3D G3DSA:1.10.10.10 121 219 5.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 2.3E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 Gene3D G3DSA:3.40.50.2300 1 120 8.5E-34 T 29-03-2018 CWR56_RS16695 c8990de4fc61fcbd4f02495adc9bf7ec 219 SMART SM00862 144 218 1.1E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02565 029f74417f17d3c78dc743da1f270d67 555 SUPERFAMILY SSF52540 289 534 7.5E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02565 029f74417f17d3c78dc743da1f270d67 555 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 292 490 1.8E-15 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CWR56_RS02565 029f74417f17d3c78dc743da1f270d67 555 Gene3D G3DSA:3.40.50.300 286 532 5.1E-31 T 29-03-2018 CWR56_RS02565 029f74417f17d3c78dc743da1f270d67 555 Gene3D G3DSA:3.30.980.10 76 241 3.9E-23 T 29-03-2018 CWR56_RS02565 029f74417f17d3c78dc743da1f270d67 555 SUPERFAMILY SSF55186 70 209 4.01E-28 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SMART SM00316 112 180 2.9 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SMART SM00316 232 302 2.8E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SMART SM00316 25 96 8.3E-13 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SMART SM00316 317 388 4.1E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SUPERFAMILY SSF50249 113 193 6.86E-10 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Pfam PF00575 S1 RNA binding domain 231 302 5.7E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Pfam PF00575 S1 RNA binding domain 23 95 4.7E-11 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Pfam PF00575 S1 RNA binding domain 316 388 1.6E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SUPERFAMILY SSF50249 9 120 3.13E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Gene3D G3DSA:2.40.50.140 224 308 4.3E-25 T 29-03-2018 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Gene3D G3DSA:2.40.50.140 17 102 3.7E-16 T 29-03-2018 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Gene3D G3DSA:2.40.50.140 105 186 1.5E-7 T 29-03-2018 CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SUPERFAMILY SSF50249 304 391 3.29E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 SUPERFAMILY SSF50249 231 316 7.01E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS04470 0bb01f32de6c1bafc17bf8dd61461ba7 424 Gene3D G3DSA:2.40.50.140 309 402 2.6E-20 T 29-03-2018 CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Gene3D G3DSA:3.30.450.20 163 292 1.3E-14 T 29-03-2018 CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 SMART SM00052 496 742 3.3E-102 T 29-03-2018 IPR001633 EAL domain CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Pfam PF00563 EAL domain 502 737 2.8E-74 T 29-03-2018 IPR001633 EAL domain CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Gene3D G3DSA:3.20.20.450 493 746 6.2E-94 T 29-03-2018 IPR001633 EAL domain CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Pfam PF00990 Diguanylate cyclase, GGDEF domain 328 477 1.2E-24 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Gene3D G3DSA:3.30.70.270 321 492 1.8E-32 T 29-03-2018 CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 SMART SM00267 316 486 6.0E-18 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 SUPERFAMILY SSF141868 501 751 1.12E-87 T 29-03-2018 IPR001633 EAL domain CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Gene3D G3DSA:3.30.450.20 41 162 7.7E-7 T 29-03-2018 CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 SUPERFAMILY SSF55073 333 485 7.14E-26 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 Pfam PF02743 Cache domain 37 276 1.3E-19 T 29-03-2018 IPR033479 Double Cache domain 1 CWR56_RS13475 68b17ddc3d96fd570bf3e7712a87f92d 759 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 323 469 8.5E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14330 fd11fb242d3f7e815c552c2b78cc54dc 458 Gene3D G3DSA:1.10.10.10 362 449 2.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Pfam PF07498 Rho termination factor, N-terminal domain 11 50 1.5E-9 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 SUPERFAMILY SSF52540 231 481 1.4E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 SUPERFAMILY SSF50249 167 238 3.48E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 269 473 3.8E-20 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Gene3D G3DSA:1.10.720.10 11 46 1.3E-9 T 29-03-2018 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Pfam PF07497 Rho termination factor, RNA-binding domain 168 238 1.9E-29 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 TIGRFAM TIGR00767 rho: transcription termination factor Rho 9 527 1.4E-180 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Gene3D G3DSA:3.40.50.300 242 529 1.2E-48 T 29-03-2018 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 SMART SM00382 280 465 5.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 SMART SM00959 10 51 3.4E-8 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 SMART SM00357 167 231 4.6E-11 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Hamap MF_01884 Transcription termination factor Rho [rho]. 168 529 182.731 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CWR56_RS17390 dbc2ad0931bf8e51b04815a0435bfc4d 529 Gene3D G3DSA:2.40.50.140 165 229 3.6E-27 T 29-03-2018 CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 SUPERFAMILY SSF52518 4 205 1.61E-72 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 Pfam PF02779 Transketolase, pyrimidine binding domain 5 181 7.0E-54 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 SMART SM00861 6 181 2.8E-69 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 SUPERFAMILY SSF52922 191 326 2.09E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 Pfam PF02780 Transketolase, C-terminal domain 195 318 5.3E-42 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 Gene3D G3DSA:3.40.50.970 2 195 1.0E-73 T 29-03-2018 CWR56_RS18910 b1629ef10a527ade571c9cec6752bded 328 Gene3D G3DSA:3.40.50.920 196 327 3.4E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS07985 478fb5556b5ef060b61b820d4eb5ac78 274 Pfam PF05857 TraX protein 9 267 2.7E-43 T 29-03-2018 IPR008875 TraX CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 Gene3D G3DSA:3.40.50.10800 179 283 2.2E-32 T 29-03-2018 CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 Gene3D G3DSA:3.40.50.10800 5 92 1.2E-21 T 29-03-2018 CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 Gene3D G3DSA:3.40.50.10800 93 178 5.7E-28 T 29-03-2018 CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 Hamap MF_00568 Quinolinate synthase A [nadA]. 3 301 42.068 T 29-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 301 1.1E-101 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 SUPERFAMILY SSF142754 4 300 1.31E-113 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CWR56_RS11790 592fcfc573b2147cbffe210fe77029c4 304 Pfam PF02445 Quinolinate synthetase A protein 8 299 4.7E-117 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 Hamap MF_01694 Biotin synthase [bioB]. 16 325 40.873 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 PIRSF PIRSF001619 1 325 9.3E-109 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 Pfam PF04055 Radical SAM superfamily 68 222 3.3E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 SUPERFAMILY SSF102114 16 321 1.24E-69 T 29-03-2018 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 SMART SM00729 59 267 7.1E-34 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 Gene3D G3DSA:3.20.20.70 1 321 2.2E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 TIGRFAM TIGR00433 bioB: biotin synthase 34 323 9.6E-117 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 SMART SM00876 235 325 3.3E-28 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS01530 64f0b484f89fd2da80d2a6e1fc408ecb 325 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 235 324 2.5E-14 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 SMART SM00086 317 359 8.3E-7 T 29-03-2018 IPR001610 PAC motif CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 367 528 2.2E-40 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 240 365 2.4E-8 T 29-03-2018 IPR000014 PAS domain CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 Gene3D G3DSA:3.30.70.270 375 537 5.5E-45 T 29-03-2018 CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 Pfam PF08447 PAS fold 266 353 2.8E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 SMART SM00267 359 530 2.8E-39 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 Pfam PF00990 Diguanylate cyclase, GGDEF domain 371 525 1.8E-36 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 Gene3D G3DSA:3.30.450.20 218 374 1.3E-18 T 29-03-2018 CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 SUPERFAMILY SSF55073 375 532 1.96E-39 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS04620 c8a3aa5d9c974a72bc87227612fd2b5f 537 SUPERFAMILY SSF55785 247 356 1.69E-14 T 29-03-2018 IPR000014 PAS domain CWR56_RS18590 9704ab904fd598f670e346147fb79642 401 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 232 353 4.2E-11 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR56_RS18590 9704ab904fd598f670e346147fb79642 401 SUPERFAMILY SSF53756 52 399 2.15E-36 T 29-03-2018 CWR56_RS18590 9704ab904fd598f670e346147fb79642 401 Gene3D G3DSA:3.40.50.2000 208 395 6.7E-24 T 29-03-2018 CWR56_RS18590 9704ab904fd598f670e346147fb79642 401 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 152 207 1.1E-14 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CWR56_RS18590 9704ab904fd598f670e346147fb79642 401 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 130 3.8E-13 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CWR56_RS18590 9704ab904fd598f670e346147fb79642 401 Gene3D G3DSA:3.40.50.2000 1 207 1.6E-7 T 29-03-2018 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 SUPERFAMILY SSF55021 248 324 3.05E-9 T 29-03-2018 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 Gene3D G3DSA:3.30.70.260 323 396 1.8E-16 T 29-03-2018 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 Pfam PF00696 Amino acid kinase family 3 227 8.9E-50 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 Gene3D G3DSA:3.40.1160.10 1 236 5.4E-64 T 29-03-2018 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 395 1.4E-91 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 SUPERFAMILY SSF53633 3 241 3.27E-67 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 Gene3D G3DSA:3.30.70.260 237 322 1.8E-10 T 29-03-2018 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 PIRSF PIRSF000726 56 397 2.7E-98 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 PIRSF PIRSF000726 1 61 1.1E-16 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 SUPERFAMILY SSF55021 327 396 3.21E-16 T 29-03-2018 CWR56_RS09840 25b0d2501081520b2e453e6a27465398 397 Pfam PF13840 ACT domain 330 389 7.3E-7 T 29-03-2018 IPR027795 GATS-like ACT domain CWR56_RS14545 e390095345a2e04ac4921dc70aa0b9fb 399 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 132 396 7.1E-71 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CWR56_RS14545 e390095345a2e04ac4921dc70aa0b9fb 399 SUPERFAMILY SSF51556 350 398 2.24E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS14545 e390095345a2e04ac4921dc70aa0b9fb 399 SUPERFAMILY SSF51556 46 322 2.24E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS14545 e390095345a2e04ac4921dc70aa0b9fb 399 Gene3D G3DSA:3.20.20.140 37 399 8.7E-82 T 29-03-2018 CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 Gene3D G3DSA:3.30.360.10 142 410 2.2E-40 T 29-03-2018 CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 Gene3D G3DSA:3.40.50.720 1 141 8.5E-33 T 29-03-2018 CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 SUPERFAMILY SSF51735 3 157 1.5E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 SUPERFAMILY SSF55347 134 220 1.22E-26 T 29-03-2018 CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 SUPERFAMILY SSF55347 272 362 1.22E-26 T 29-03-2018 CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 125 3.2E-20 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CWR56_RS06515 e81a5ca1c48e98aae150c5a992a3a0ba 428 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 217 7.2E-9 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CWR56_RS14310 86e88c28ce1c627c18eeca8885c37e37 370 Pfam PF01168 Alanine racemase, N-terminal domain 13 237 5.2E-29 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS14310 86e88c28ce1c627c18eeca8885c37e37 370 Pfam PF14031 Putative serine dehydratase domain 253 345 1.6E-19 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CWR56_RS14310 86e88c28ce1c627c18eeca8885c37e37 370 Gene3D G3DSA:3.20.20.10 15 240 1.7E-39 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS14310 86e88c28ce1c627c18eeca8885c37e37 370 SMART SM01119 253 349 2.2E-37 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CWR56_RS14310 86e88c28ce1c627c18eeca8885c37e37 370 SUPERFAMILY SSF51419 13 241 2.83E-37 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS06960 205f147e384942b7461fe69529521928 73 SMART SM00899 2 73 1.3E-17 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS06960 205f147e384942b7461fe69529521928 73 Pfam PF04023 FeoA domain 3 73 2.6E-16 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS06960 205f147e384942b7461fe69529521928 73 SUPERFAMILY SSF50037 6 73 2.01E-20 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR56_RS06960 205f147e384942b7461fe69529521928 73 Gene3D G3DSA:2.30.30.90 5 73 1.4E-19 T 29-03-2018 CWR56_RS04465 32a9c403e78d0b435453450f770f370b 455 PIRSF PIRSF006603 1 455 3.7E-81 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS04465 32a9c403e78d0b435453450f770f370b 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 417 7.3E-57 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS04465 32a9c403e78d0b435453450f770f370b 455 Pfam PF01554 MatE 249 407 2.9E-17 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS04465 32a9c403e78d0b435453450f770f370b 455 Pfam PF01554 MatE 23 185 4.6E-23 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 PRINTS PR01806 Virulence factor MviN signature 36 57 1.5E-15 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 PRINTS PR01806 Virulence factor MviN signature 135 161 1.5E-15 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 PRINTS PR01806 Virulence factor MviN signature 12 36 1.5E-15 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 PRINTS PR01806 Virulence factor MviN signature 285 302 1.5E-15 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 PRINTS PR01806 Virulence factor MviN signature 233 252 1.5E-15 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 Pfam PF03023 MviN-like protein 17 348 6.7E-71 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS07080 05008506d3d18c4ffc6166e40ae63483 395 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 17 384 5.9E-83 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CWR56_RS14560 7f72e5abdfa8c0b2d57283390f3daf7e 177 SUPERFAMILY SSF47240 16 177 1.33E-42 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS14560 7f72e5abdfa8c0b2d57283390f3daf7e 177 Pfam PF00210 Ferritin-like domain 44 174 2.0E-8 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CWR56_RS14560 7f72e5abdfa8c0b2d57283390f3daf7e 177 Gene3D G3DSA:1.20.1260.10 102 177 2.6E-10 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS14560 7f72e5abdfa8c0b2d57283390f3daf7e 177 Gene3D G3DSA:1.20.1260.10 14 101 1.2E-17 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS18330 a8dc6d6daf7dd0bb9e2aad48f7373405 106 Pfam PF12643 MazG-like family 9 95 2.1E-29 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Pfam PF08239 Bacterial SH3 domain 348 398 2.0E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Pfam PF08239 Bacterial SH3 domain 418 470 5.4E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Pfam PF04122 Putative cell wall binding repeat 2 135 224 2.5E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Pfam PF04122 Putative cell wall binding repeat 2 233 313 5.1E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Pfam PF04122 Putative cell wall binding repeat 2 37 122 9.8E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Gene3D G3DSA:2.40.50.110 400 472 2.6E-18 T 29-03-2018 CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 Gene3D G3DSA:2.40.50.110 300 399 1.1E-16 T 29-03-2018 CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 SMART SM00287 409 473 1.8E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS13870 5be3a4edada32bc4ae57728d8ce8dccc 475 SMART SM00287 337 401 5.8E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS16580 c05bfa33111c695b1a5a2659498a0e88 226 Gene3D G3DSA:1.20.5.400 31 110 5.2E-4 T 29-03-2018 CWR56_RS16580 c05bfa33111c695b1a5a2659498a0e88 226 Pfam PF05949 Bacterial protein of unknown function (DUF881) 80 224 4.8E-31 T 29-03-2018 IPR010273 Protein of unknown function DUF881 CWR56_RS07950 b4e326ffea0bba4de7595b6aff915876 194 Gene3D G3DSA:2.160.10.10 1 194 2.3E-51 T 29-03-2018 CWR56_RS07950 b4e326ffea0bba4de7595b6aff915876 194 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 148 176 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR56_RS07950 b4e326ffea0bba4de7595b6aff915876 194 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 140 174 1.2E-11 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS07950 b4e326ffea0bba4de7595b6aff915876 194 SUPERFAMILY SSF51161 2 193 3.47E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS07950 b4e326ffea0bba4de7595b6aff915876 194 Pfam PF12464 Maltose acetyltransferase 6 55 4.5E-15 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWR56_RS07950 b4e326ffea0bba4de7595b6aff915876 194 SMART SM01266 4 58 3.5E-20 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWR56_RS08180 d7629d328fa99821e8b8c8eec84e3319 202 SUPERFAMILY SSF53448 24 196 1.58E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS08180 d7629d328fa99821e8b8c8eec84e3319 202 Gene3D G3DSA:3.90.550.10 22 202 8.1E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS08180 d7629d328fa99821e8b8c8eec84e3319 202 Pfam PF12804 MobA-like NTP transferase domain 25 172 2.6E-25 T 29-03-2018 IPR025877 MobA-like NTP transferase CWR56_RS08180 d7629d328fa99821e8b8c8eec84e3319 202 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 21 199 22.289 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CWR56_RS03580 b49ebef8359fe032fbad8e8fab10c9db 170 Gene3D G3DSA:3.30.300.20 25 105 0.21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS02990 0f296dd02f6daa86dbec6bb066c70509 270 Gene3D G3DSA:3.40.50.1820 2 269 6.3E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS02990 0f296dd02f6daa86dbec6bb066c70509 270 Pfam PF00561 alpha/beta hydrolase fold 31 154 1.6E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS02990 0f296dd02f6daa86dbec6bb066c70509 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS02990 0f296dd02f6daa86dbec6bb066c70509 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 5.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS02990 0f296dd02f6daa86dbec6bb066c70509 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 5.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS02990 0f296dd02f6daa86dbec6bb066c70509 270 SUPERFAMILY SSF53474 4 266 1.23E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 SMART SM00388 250 317 4.0E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 Gene3D G3DSA:1.10.287.130 232 312 7.4E-9 T 29-03-2018 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 SUPERFAMILY SSF47384 236 317 1.96E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 SUPERFAMILY SSF158472 192 239 8.37E-8 T 29-03-2018 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 Pfam PF00672 HAMP domain 191 238 8.1E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 1.9E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 1.9E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 SMART SM00304 190 242 1.1E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 Gene3D G3DSA:3.30.565.10 321 473 1.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 471 1.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 314 2.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 SMART SM00387 364 474 6.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02220 7baa873187b7ca3a006e4b9f2327a9d0 474 SUPERFAMILY SSF55874 321 471 7.73E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 59 77 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 SUPERFAMILY SSF46785 23 116 3.49E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 3.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 85 100 3.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 68 3.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 3.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 SMART SM00418 36 114 1.3E-28 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 Gene3D G3DSA:1.10.10.10 2 121 3.9E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01610 3e7e0a06e90412271cbefd143189ecbd 121 Pfam PF01022 Bacterial regulatory protein, arsR family 43 88 1.3E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS10030 8cd4361d731078b3b837baac9fe451a4 453 Pfam PF00860 Permease family 20 401 3.9E-70 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS11305 e95138349e0e3165067bbae5974118f8 148 Gene3D G3DSA:3.40.930.10 1 145 3.1E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11305 e95138349e0e3165067bbae5974118f8 148 SUPERFAMILY SSF55804 2 143 3.4E-37 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11305 e95138349e0e3165067bbae5974118f8 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 2 144 1.3E-34 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS17000 c7746eb19b5724380a3adc3065a637bf 286 SUPERFAMILY SSF161098 22 286 1.4E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17000 c7746eb19b5724380a3adc3065a637bf 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 273 6.8E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17000 c7746eb19b5724380a3adc3065a637bf 286 Gene3D G3DSA:1.10.3720.10 22 278 1.6E-43 T 29-03-2018 CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 Gene3D G3DSA:3.20.20.80 168 553 7.2E-102 T 29-03-2018 CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 SUPERFAMILY SSF51011 560 627 4.08E-5 T 29-03-2018 CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 Pfam PF00128 Alpha amylase, catalytic domain 213 512 4.7E-74 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 SUPERFAMILY SSF51445 102 554 4.17E-111 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 SUPERFAMILY SSF81296 20 135 5.04E-18 T 29-03-2018 IPR014756 Immunoglobulin E-set CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 25 162 3.3E-28 T 29-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 Gene3D G3DSA:2.60.40.10 23 166 3.1E-33 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS10570 82425c2a7fc53f950d150d9dd0976be6 627 SMART SM00642 180 547 8.0E-103 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS03150 369488435061016f1cd9b39c7fe5b926 232 Gene3D G3DSA:1.20.1000.10 13 132 0.0012 T 29-03-2018 CWR56_RS06945 8b3370de19447a4355f21b7fcec1666e 201 SUPERFAMILY SSF53474 13 200 2.87E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS06945 8b3370de19447a4355f21b7fcec1666e 201 Pfam PF01738 Dienelactone hydrolase family 13 198 5.6E-20 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CWR56_RS06945 8b3370de19447a4355f21b7fcec1666e 201 Gene3D G3DSA:3.40.50.1820 9 185 2.0E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS01505 16a73a62c5e4ca3cd8d46c29a9ab82e9 66 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 63 1.5E-11 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CWR56_RS02145 1ccf0b3ae2c629b02c1026dd68a2d132 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 265 3.1E-51 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS02145 1ccf0b3ae2c629b02c1026dd68a2d132 271 SUPERFAMILY SSF56784 2 267 4.31E-54 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS02145 1ccf0b3ae2c629b02c1026dd68a2d132 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 238 8.4E-22 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR56_RS02145 1ccf0b3ae2c629b02c1026dd68a2d132 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 2.2E-49 T 29-03-2018 IPR000150 Cof family GO:0016787 CWR56_RS02145 1ccf0b3ae2c629b02c1026dd68a2d132 271 Gene3D G3DSA:3.40.50.1000 2 271 4.3E-32 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 6.8E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 6.8E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 6.8E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 6.8E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 Gene3D G3DSA:1.20.5.1150 16 52 3.1E-18 T 29-03-2018 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 Pfam PF01165 Ribosomal protein S21 3 56 1.4E-22 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 59 1.4E-22 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.091 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS12360 fd0efb65f89a673dad6f9e2e0a80d66c 59 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 6.0E-8 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 189 199 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 Pfam PF00483 Nucleotidyl transferase 7 260 5.4E-68 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 Gene3D G3DSA:2.160.10.10 267 381 3.1E-16 T 29-03-2018 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 SUPERFAMILY SSF51161 268 361 2.22E-15 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 SUPERFAMILY SSF53448 1 263 1.59E-86 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 SUPERFAMILY SSF53448 324 340 1.59E-86 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 361 9.1E-140 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 375 46.807 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWR56_RS04335 742c0a68612ce576599cc2ef626b2d8c 386 Gene3D G3DSA:3.90.550.10 1 266 1.3E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS12760 14ac2dab7eecaa4f5c785c7c832ed05b 229 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 32 224 7.3E-56 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CWR56_RS12760 14ac2dab7eecaa4f5c785c7c832ed05b 229 Pfam PF01467 Cytidylyltransferase-like 32 198 2.1E-28 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR56_RS12760 14ac2dab7eecaa4f5c785c7c832ed05b 229 Gene3D G3DSA:3.40.50.620 23 226 4.4E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS12760 14ac2dab7eecaa4f5c785c7c832ed05b 229 SUPERFAMILY SSF52374 29 226 4.38E-51 T 29-03-2018 CWR56_RS12760 14ac2dab7eecaa4f5c785c7c832ed05b 229 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 30 93 4.3E-9 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR56_RS12760 14ac2dab7eecaa4f5c785c7c832ed05b 229 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 28 225 30.329 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CWR56_RS01410 3c5d2f7e6c680cc1f42c4454f7389769 340 SUPERFAMILY SSF102114 83 273 7.72E-5 T 29-03-2018 CWR56_RS01410 3c5d2f7e6c680cc1f42c4454f7389769 340 Pfam PF04055 Radical SAM superfamily 85 243 3.1E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS01410 3c5d2f7e6c680cc1f42c4454f7389769 340 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 2 340 9.6E-171 T 29-03-2018 IPR023897 Spore photoproduct lyase GO:0003913 CWR56_RS01410 3c5d2f7e6c680cc1f42c4454f7389769 340 Gene3D G3DSA:3.80.30.20 77 304 4.6E-8 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 SUPERFAMILY SSF51735 5 166 9.92E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 162 1.6E-45 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 Gene3D G3DSA:1.10.1040.10 170 297 1.4E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 PIRSF PIRSF000103 1 297 1.4E-74 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 10 23 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 287 3.3E-33 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 SUPERFAMILY SSF48179 166 296 4.85E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 7 296 2.8E-103 T 29-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 CWR56_RS14275 1df62a4028047ab1fcabb39d5f9af6c0 301 Gene3D G3DSA:3.40.50.720 4 169 8.6E-27 T 29-03-2018 CWR56_RS01820 1a9c73a8783a27719be77f8e36c039b8 186 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 6 182 1.5E-10 T 29-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CWR56_RS01820 1a9c73a8783a27719be77f8e36c039b8 186 Gene3D G3DSA:3.40.50.1000 50 185 4.2E-27 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01820 1a9c73a8783a27719be77f8e36c039b8 186 PIRSF PIRSF021362 3 186 3.3E-47 T 29-03-2018 IPR009206 Nucleotidase, putative CWR56_RS01820 1a9c73a8783a27719be77f8e36c039b8 186 SUPERFAMILY SSF56784 63 164 3.83E-21 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01820 1a9c73a8783a27719be77f8e36c039b8 186 SUPERFAMILY SSF56784 5 17 3.83E-21 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS05355 84774d15bed6668ccc39860c2e032004 58 Pfam PF01783 Ribosomal L32p protein family 2 58 1.6E-27 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05355 84774d15bed6668ccc39860c2e032004 58 SUPERFAMILY SSF57829 1 56 2.08E-22 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWR56_RS05355 84774d15bed6668ccc39860c2e032004 58 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 1.0E-27 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05355 84774d15bed6668ccc39860c2e032004 58 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 56 20.74 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS10525 2623da08a81e7b334cc1e0f6bdbb6647 254 SUPERFAMILY SSF53474 2 253 1.05E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS10525 2623da08a81e7b334cc1e0f6bdbb6647 254 Gene3D G3DSA:3.40.50.1820 2 253 2.0E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS10525 2623da08a81e7b334cc1e0f6bdbb6647 254 Pfam PF00561 alpha/beta hydrolase fold 21 158 5.6E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS10525 2623da08a81e7b334cc1e0f6bdbb6647 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 4.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS10525 2623da08a81e7b334cc1e0f6bdbb6647 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 4.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS10525 2623da08a81e7b334cc1e0f6bdbb6647 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 4.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS09810 d33d6c040f80e6e3909f2cd94cb7edf1 290 SUPERFAMILY SSF53697 106 262 2.02E-28 T 29-03-2018 CWR56_RS09810 d33d6c040f80e6e3909f2cd94cb7edf1 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 13 85 1.4E-15 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS09810 d33d6c040f80e6e3909f2cd94cb7edf1 290 Pfam PF01380 SIS domain 137 262 3.4E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS09810 d33d6c040f80e6e3909f2cd94cb7edf1 290 Gene3D G3DSA:1.10.10.10 7 87 7.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09810 d33d6c040f80e6e3909f2cd94cb7edf1 290 Gene3D G3DSA:3.40.50.10490 96 287 3.4E-26 T 29-03-2018 CWR56_RS09810 d33d6c040f80e6e3909f2cd94cb7edf1 290 SUPERFAMILY SSF46689 12 88 1.11E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 19 281 9.0E-82 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 Gene3D G3DSA:1.10.8.100 223 282 4.2E-22 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 19 283 54.195 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 Gene3D G3DSA:3.40.50.150 2 222 3.7E-59 T 29-03-2018 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 SMART SM00650 35 210 8.1E-75 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 Pfam PF00398 Ribosomal RNA adenine dimethylase 19 274 2.0E-66 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWR56_RS17570 6ccba11f9b13407ecb24b95ee165029e 289 SUPERFAMILY SSF53335 17 283 1.64E-73 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS01795 f730b1239f1325d2ad00c8818b8e4193 303 SMART SM00849 18 209 2.6E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS01795 f730b1239f1325d2ad00c8818b8e4193 303 Pfam PF00753 Metallo-beta-lactamase superfamily 17 209 1.0E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS01795 f730b1239f1325d2ad00c8818b8e4193 303 SUPERFAMILY SSF56281 4 286 2.94E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS01795 f730b1239f1325d2ad00c8818b8e4193 303 Gene3D G3DSA:3.60.15.10 4 268 3.9E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12575 e73be04e86445597d241805e507dfc3b 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 147 1.1E-36 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS12575 e73be04e86445597d241805e507dfc3b 151 Gene3D G3DSA:3.40.930.10 1 149 5.5E-33 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS12575 e73be04e86445597d241805e507dfc3b 151 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 132 1.1E-32 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS12575 e73be04e86445597d241805e507dfc3b 151 SUPERFAMILY SSF55804 3 147 6.67E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS07850 90d356a45aee3fdfc6590e3c36d39071 318 Pfam PF01032 FecCD transport family 29 314 5.4E-50 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR56_RS07850 90d356a45aee3fdfc6590e3c36d39071 318 Gene3D G3DSA:1.10.3470.10 6 318 2.0E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS07850 90d356a45aee3fdfc6590e3c36d39071 318 SUPERFAMILY SSF81345 9 314 4.32E-55 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CWR56_RS13910 487e07f84c901b73fbd77302dcba01d3 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 3.8E-59 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWR56_RS13910 487e07f84c901b73fbd77302dcba01d3 149 SUPERFAMILY SSF69500 1 145 1.31E-59 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CWR56_RS13910 487e07f84c901b73fbd77302dcba01d3 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.8E-63 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWR56_RS13910 487e07f84c901b73fbd77302dcba01d3 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.854 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWR56_RS13910 487e07f84c901b73fbd77302dcba01d3 149 Gene3D G3DSA:3.50.80.10 1 145 1.1E-60 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 SUPERFAMILY SSF52540 201 375 7.8E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 Gene3D G3DSA:1.20.120.430 273 406 1.3E-13 T 29-03-2018 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 Pfam PF16360 GTP-binding GTPase Middle Region 118 196 2.4E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 279 297 1.4E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 204 224 1.4E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 Pfam PF13167 GTP-binding GTPase N-terminal 29 116 2.3E-33 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 Pfam PF01926 50S ribosome-binding GTPase 204 330 8.7E-20 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 Gene3D G3DSA:3.40.50.300 1 271 2.2E-14 T 29-03-2018 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 Hamap MF_00900 GTPase HflX [hflX]. 31 397 45.659 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 PIRSF PIRSF006809 1 426 5.7E-143 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CWR56_RS03850 242c30f35339313c75ddac204c4915f8 427 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 19 365 1.5E-136 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CWR56_RS11850 72a84e28b0d05ba85c713bb8ce9b2ffe 142 SUPERFAMILY SSF88659 73 136 8.04E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS11850 72a84e28b0d05ba85c713bb8ce9b2ffe 142 Gene3D G3DSA:1.10.10.10 71 141 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11850 72a84e28b0d05ba85c713bb8ce9b2ffe 142 Pfam PF08281 Sigma-70, region 4 80 119 7.1E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 30 98 4.4E-18 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 SUPERFAMILY SSF101801 28 102 7.19E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 Gene3D G3DSA:2.30.330.10 17 104 3.9E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 PRINTS PR00956 Flagellar motor switch protein FliN signature 46 62 3.2E-13 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 PRINTS PR00956 Flagellar motor switch protein FliN signature 29 45 3.2E-13 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 PRINTS PR00956 Flagellar motor switch protein FliN signature 75 90 3.2E-13 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS01150 fb4766cc58b4cef52e59bce281a4d10f 104 PRINTS PR00956 Flagellar motor switch protein FliN signature 62 75 3.2E-13 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 Gene3D G3DSA:2.10.240.10 226 258 1.4E-9 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 Gene3D G3DSA:2.40.30.10 5 84 2.2E-9 T 29-03-2018 CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 Gene3D G3DSA:3.40.50.80 85 223 2.5E-20 T 29-03-2018 CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 SUPERFAMILY SSF63380 5 94 3.05E-18 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 PIRSF PIRSF006816 3 263 5.8E-76 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 226 256 1.6E-7 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 Pfam PF00175 Oxidoreductase NAD-binding domain 107 207 2.2E-12 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 TIGRFAM TIGR02911 sulfite_red_B: sulfite reductase, subunit B 3 263 2.0E-124 T 29-03-2018 IPR014260 Sulphite reductase, subunit B CWR56_RS10800 91152c9aa5e96f09662d4ec123db9f09 263 SUPERFAMILY SSF52343 89 257 2.75E-28 T 29-03-2018 CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 SUPERFAMILY SSF53335 153 606 2.3E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 437 443 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 434 446 6.7E-11 T 29-03-2018 CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 329 343 6.7E-11 T 29-03-2018 CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 316 6.7E-11 T 29-03-2018 CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 Pfam PF02384 N-6 DNA Methylase 282 548 4.9E-16 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWR56_RS01975 c904cae44c77456db6bf2294df942a0f 979 Gene3D G3DSA:3.40.50.150 298 924 1.0E-32 T 29-03-2018 CWR56_RS12870 f7e7ba15496a4c243883fac15872dc56 340 Gene3D G3DSA:3.20.20.80 27 340 1.5E-55 T 29-03-2018 CWR56_RS12870 f7e7ba15496a4c243883fac15872dc56 340 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 60 314 6.1E-54 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CWR56_RS12870 f7e7ba15496a4c243883fac15872dc56 340 SUPERFAMILY SSF51445 38 337 2.97E-70 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS09460 9155f2928be5a60a3aa2f1e260debb99 203 ProSitePatterns PS00893 Nudix box signature. 61 82 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR56_RS09460 9155f2928be5a60a3aa2f1e260debb99 203 Gene3D G3DSA:3.90.79.10 2 202 9.4E-35 T 29-03-2018 CWR56_RS09460 9155f2928be5a60a3aa2f1e260debb99 203 SUPERFAMILY SSF55811 5 194 1.76E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS09460 9155f2928be5a60a3aa2f1e260debb99 203 Pfam PF00293 NUDIX domain 24 136 6.3E-13 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS10540 8a48b4fac2177f2b49fdf841a85981ad 180 Gene3D G3DSA:3.40.630.40 1 178 2.5E-29 T 29-03-2018 CWR56_RS10540 8a48b4fac2177f2b49fdf841a85981ad 180 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 3 174 1.6E-24 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS10540 8a48b4fac2177f2b49fdf841a85981ad 180 SMART SM00646 69 174 2.7E-13 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS10540 8a48b4fac2177f2b49fdf841a85981ad 180 SUPERFAMILY SSF53187 1 175 1.41E-31 T 29-03-2018 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 3.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 3.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 3.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 Gene3D G3DSA:3.40.190.10 89 178 9.8E-16 T 29-03-2018 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 SUPERFAMILY SSF46785 4 111 3.24E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 1.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 SUPERFAMILY SSF53850 90 288 2.26E-31 T 29-03-2018 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 Gene3D G3DSA:1.10.10.10 2 84 9.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 Gene3D G3DSA:3.40.190.10 179 262 3.9E-10 T 29-03-2018 CWR56_RS00940 27a1b8d46e71558d401bb240b10a8d32 296 Pfam PF03466 LysR substrate binding domain 89 288 1.5E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS18275 01fb898cb66af96d75518e9ac8145ee0 330 Pfam PF01695 IstB-like ATP binding protein 183 311 3.8E-14 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CWR56_RS18275 01fb898cb66af96d75518e9ac8145ee0 330 SUPERFAMILY SSF52540 179 322 4.0E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18275 01fb898cb66af96d75518e9ac8145ee0 330 SMART SM00382 184 317 2.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS18275 01fb898cb66af96d75518e9ac8145ee0 330 Gene3D G3DSA:3.40.50.300 58 316 3.9E-16 T 29-03-2018 CWR56_RS05630 2c2f7d96fb2d80c36043cf333254ffd4 505 Pfam PF07508 Recombinase 181 291 6.0E-25 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWR56_RS05630 2c2f7d96fb2d80c36043cf333254ffd4 505 SUPERFAMILY SSF53041 1 155 2.75E-23 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS05630 2c2f7d96fb2d80c36043cf333254ffd4 505 Gene3D G3DSA:3.40.50.1390 1 164 1.1E-30 T 29-03-2018 CWR56_RS05630 2c2f7d96fb2d80c36043cf333254ffd4 505 SMART SM00857 3 156 2.3E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS05630 2c2f7d96fb2d80c36043cf333254ffd4 505 Gene3D G3DSA:1.20.1480.30 413 482 1.3E-4 T 29-03-2018 CWR56_RS05630 2c2f7d96fb2d80c36043cf333254ffd4 505 Pfam PF00239 Resolvase, N terminal domain 3 154 5.3E-20 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 Pfam PF00874 PRD domain 184 275 2.4E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 Pfam PF00874 PRD domain 77 165 1.8E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 SUPERFAMILY SSF63520 173 276 1.7E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 Gene3D G3DSA:2.30.24.10 1 57 2.8E-19 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 Gene3D G3DSA:1.10.1790.10 58 168 1.4E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 Gene3D G3DSA:1.10.1790.10 169 278 6.0E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 SUPERFAMILY SSF50151 3 55 4.97E-13 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 SMART SM01061 3 61 6.2E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 Pfam PF03123 CAT RNA binding domain 3 58 7.9E-16 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS01855 603dd312d491ad70b20bd8aefc68ef58 278 SUPERFAMILY SSF63520 60 167 2.22E-28 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS03070 c32b2082fbb41adde40032a13427e6db 651 SUPERFAMILY SSF69304 196 384 3.14E-18 T 29-03-2018 CWR56_RS03070 c32b2082fbb41adde40032a13427e6db 651 SUPERFAMILY SSF69304 18 124 3.14E-18 T 29-03-2018 CWR56_RS03070 c32b2082fbb41adde40032a13427e6db 651 SUPERFAMILY SSF53474 395 651 1.44E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS03070 c32b2082fbb41adde40032a13427e6db 651 Gene3D G3DSA:3.40.50.1820 343 651 7.5E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS03070 c32b2082fbb41adde40032a13427e6db 651 Pfam PF00326 Prolyl oligopeptidase family 442 651 6.9E-46 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CWR56_RS03070 c32b2082fbb41adde40032a13427e6db 651 Gene3D G3DSA:2.140.10.30 7 285 3.0E-16 T 29-03-2018 CWR56_RS09550 cc575fb4d5e02bde15937657e5161a16 250 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 5.6E-48 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 SUPERFAMILY SSF50193 1 122 1.57E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-56 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.5E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 SMART SM01374 1 122 5.7E-86 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.461 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR56_RS00135 c7fc673595c288a0606cb18bc71e74c7 122 Gene3D G3DSA:2.40.150.20 1 122 2.5E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 SUPERFAMILY SSF55785 246 354 7.42E-12 T 29-03-2018 IPR000014 PAS domain CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 SUPERFAMILY SSF47384 352 432 3.34E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 241 358 4.4E-10 T 29-03-2018 IPR000014 PAS domain CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 Gene3D G3DSA:3.30.565.10 446 617 2.0E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 Gene3D G3DSA:1.10.287.130 361 428 1.2E-16 T 29-03-2018 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 Pfam PF08448 PAS fold 246 354 2.3E-9 T 29-03-2018 IPR013656 PAS fold-4 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 432 2.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 Gene3D G3DSA:3.30.450.20 231 360 1.2E-14 T 29-03-2018 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 SUPERFAMILY SSF55874 421 593 1.15E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 529 2.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 543 2.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 568 2.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 PRINTS PR00344 Bacterial sensor protein C-terminal signature 574 587 2.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 479 588 1.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 SMART SM00388 362 432 8.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS07480 ba41ff21f805bec589a81cdadca4969c 618 SMART SM00387 478 590 3.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04655 e32dace5252c2513391e87592c56b65e 635 Pfam PF08757 CotH kinase protein 90 391 2.6E-67 T 29-03-2018 IPR014867 Spore coat protein CotH CWR56_RS09120 0c0a85b2819dfb6465987e96fe26a1e8 241 TIGRFAM TIGR02536 eut_hyp: ethanolamine utilization protein 11 239 7.9E-49 T 29-03-2018 IPR013372 Ethanolamine utilization, putative CWR56_RS09120 0c0a85b2819dfb6465987e96fe26a1e8 241 PIRSF PIRSF034981 160 241 0.0023 T 29-03-2018 IPR013372 Ethanolamine utilization, putative CWR56_RS09120 0c0a85b2819dfb6465987e96fe26a1e8 241 PIRSF PIRSF034981 1 177 7.5E-14 T 29-03-2018 IPR013372 Ethanolamine utilization, putative CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 SUPERFAMILY SSF53067 158 335 2.16E-49 T 29-03-2018 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 Gene3D G3DSA:3.90.640.10 203 261 8.5E-34 T 29-03-2018 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 140 159 5.9E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 77 100 5.9E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 57 75 5.9E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 308 334 5.9E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 195 215 5.9E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 19 343 1.2E-153 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 Gene3D G3DSA:3.30.420.40 17 166 5.9E-42 T 29-03-2018 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 Gene3D G3DSA:3.30.420.40 167 202 7.3E-4 T 29-03-2018 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 Pfam PF06723 MreB/Mbl protein 20 341 2.6E-154 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 SUPERFAMILY SSF53067 19 156 1.99E-43 T 29-03-2018 CWR56_RS05195 aa89bbe9fde992e926b8ef9496e3f4b6 353 Gene3D G3DSA:3.30.420.40 262 325 5.6E-11 T 29-03-2018 CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 SUPERFAMILY SSF53187 284 364 6.57E-63 T 29-03-2018 CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 SUPERFAMILY SSF53187 4 183 6.57E-63 T 29-03-2018 CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 Pfam PF07687 Peptidase dimerisation domain 172 249 1.0E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 PIRSF PIRSF005962 1 370 7.9E-111 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 Pfam PF01546 Peptidase family M20/M25/M40 70 366 7.2E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 SUPERFAMILY SSF55031 172 280 1.96E-25 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 Gene3D G3DSA:3.40.630.10 1 266 1.4E-51 T 29-03-2018 CWR56_RS16185 b2cd3cdb5231c6f0c1e0eda353ff9588 372 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 354 4.7E-83 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS15090 c2ed3170a59ce0fd47b24f948e003ced 156 Gene3D G3DSA:2.70.70.10 1 156 4.7E-52 T 29-03-2018 CWR56_RS15090 c2ed3170a59ce0fd47b24f948e003ced 156 SUPERFAMILY SSF51261 3 151 3.14E-51 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS15090 c2ed3170a59ce0fd47b24f948e003ced 156 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 9 133 2.3E-47 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15090 c2ed3170a59ce0fd47b24f948e003ced 156 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 10 130 2.8E-40 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15090 c2ed3170a59ce0fd47b24f948e003ced 156 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 72 84 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Pfam PF04073 Aminoacyl-tRNA editing domain 256 375 5.7E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Gene3D G3DSA:3.40.50.800 458 566 2.6E-30 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 SUPERFAMILY SSF52954 458 562 1.96E-31 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 SUPERFAMILY SSF55826 218 380 8.11E-30 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.8E-13 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.8E-13 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.8E-13 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.8E-13 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Gene3D G3DSA:3.90.960.10 253 371 4.0E-36 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 3.1E-214 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 SUPERFAMILY SSF55681 9 237 1.26E-99 T 29-03-2018 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 SUPERFAMILY SSF55681 402 473 1.26E-99 T 29-03-2018 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 39.81 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Gene3D G3DSA:3.30.930.10 372 457 2.1E-20 T 29-03-2018 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Gene3D G3DSA:3.30.930.10 1 252 7.1E-67 T 29-03-2018 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 454 2.2E-49 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS18970 e8261356a57a9a1d176d539331ee15a5 571 Pfam PF03129 Anticodon binding domain 470 561 1.7E-18 T 29-03-2018 IPR004154 Anticodon-binding CWR56_RS06625 c3fd4e9c0dfff1fb1ccc7ae8b8a31756 182 Pfam PF03729 Short repeat of unknown function (DUF308) 137 181 0.0081 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane CWR56_RS06625 c3fd4e9c0dfff1fb1ccc7ae8b8a31756 182 Pfam PF03729 Short repeat of unknown function (DUF308) 23 71 1.1E-7 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane CWR56_RS09355 6f99f1c66e0f8357d339dbd0e8063697 195 SUPERFAMILY SSF46689 6 73 2.36E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09355 6f99f1c66e0f8357d339dbd0e8063697 195 Gene3D G3DSA:1.10.357.10 2 81 3.0E-5 T 29-03-2018 CWR56_RS09355 6f99f1c66e0f8357d339dbd0e8063697 195 Pfam PF13305 WHG domain 87 165 4.0E-7 T 29-03-2018 IPR025996 WHG domain CWR56_RS04200 ad0fe12bf946b1417ba4374e1de2daef 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 293 8.1E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04200 ad0fe12bf946b1417ba4374e1de2daef 303 SUPERFAMILY SSF161098 92 281 1.42E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04200 ad0fe12bf946b1417ba4374e1de2daef 303 Gene3D G3DSA:1.10.3720.10 37 302 3.0E-36 T 29-03-2018 CWR56_RS10845 308772c3d5f1c7e77ceb96abf1b13a34 223 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 27 221 4.4E-72 T 29-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CWR56_RS10845 308772c3d5f1c7e77ceb96abf1b13a34 223 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 3 221 40.561 T 29-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CWR56_RS10845 308772c3d5f1c7e77ceb96abf1b13a34 223 SUPERFAMILY SSF51366 3 220 2.04E-61 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS10845 308772c3d5f1c7e77ceb96abf1b13a34 223 Gene3D G3DSA:3.20.20.70 1 222 1.6E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 Pfam PF02310 B12 binding domain 598 713 1.1E-14 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 Pfam PF09043 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 60 441 1.1E-45 T 29-03-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 SUPERFAMILY SSF51703 4 447 7.06E-171 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 SUPERFAMILY SSF52242 595 729 1.57E-31 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 Gene3D G3DSA:3.20.20.440 1 444 1.2E-181 T 29-03-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 Pfam PF16554 Dimerisation domain of d-ornithine 4,5-aminomutase 502 579 9.3E-30 T 29-03-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 CWR56_RS02055 815c4557b85bffc3383dc829425fbd43 734 Gene3D G3DSA:3.40.50.280 588 731 1.5E-28 T 29-03-2018 CWR56_RS03455 08392c5e825767022bfb07db2b814d71 192 SUPERFAMILY SSF51161 29 188 3.33E-45 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS03455 08392c5e825767022bfb07db2b814d71 192 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 142 170 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR56_RS03455 08392c5e825767022bfb07db2b814d71 192 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 79 114 3.2E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS03455 08392c5e825767022bfb07db2b814d71 192 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 133 168 6.9E-12 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS03455 08392c5e825767022bfb07db2b814d71 192 Gene3D G3DSA:2.160.10.10 8 191 2.6E-45 T 29-03-2018 CWR56_RS17580 9b37d871f72bd89a72a3235534eb007d 355 PIRSF PIRSF002825 1 348 5.7E-91 T 29-03-2018 IPR026045 Ferric binding protein CWR56_RS17580 9b37d871f72bd89a72a3235534eb007d 355 SUPERFAMILY SSF53850 39 343 3.26E-66 T 29-03-2018 CWR56_RS17580 9b37d871f72bd89a72a3235534eb007d 355 Gene3D G3DSA:3.40.190.10 23 156 9.1E-13 T 29-03-2018 CWR56_RS17580 9b37d871f72bd89a72a3235534eb007d 355 Pfam PF13343 Bacterial extracellular solute-binding protein 89 320 2.6E-29 T 29-03-2018 CWR56_RS17580 9b37d871f72bd89a72a3235534eb007d 355 Gene3D G3DSA:3.40.190.10 157 282 8.2E-29 T 29-03-2018 CWR56_RS17580 9b37d871f72bd89a72a3235534eb007d 355 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 33 352 3.7E-135 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 SUPERFAMILY SSF52172 1 173 3.66E-42 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 Gene3D G3DSA:3.40.50.2300 1 120 2.1E-37 T 29-03-2018 CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 2.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 Pfam PF00072 Response regulator receiver domain 4 113 8.4E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 SMART SM00448 2 112 8.6E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 Gene3D G3DSA:1.10.10.10 121 223 3.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16085 2fd88cda24d681e2f8de1df957118304 223 SMART SM00862 146 219 8.0E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS15705 7b7e12bee33c3f1f91ea091fa280f030 220 Pfam PF00005 ABC transporter 24 169 6.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS15705 7b7e12bee33c3f1f91ea091fa280f030 220 SMART SM00382 32 218 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15705 7b7e12bee33c3f1f91ea091fa280f030 220 Gene3D G3DSA:3.40.50.300 1 220 1.1E-56 T 29-03-2018 CWR56_RS15705 7b7e12bee33c3f1f91ea091fa280f030 220 SUPERFAMILY SSF52540 3 219 2.6E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS15705 7b7e12bee33c3f1f91ea091fa280f030 220 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 1.1E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 Gene3D G3DSA:3.40.50.2300 2 128 1.1E-32 T 29-03-2018 CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 SMART SM00448 3 113 7.8E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 SUPERFAMILY SSF52172 2 133 1.25E-39 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 Gene3D G3DSA:1.10.10.10 129 233 5.7E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 SMART SM00862 155 231 6.5E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 SUPERFAMILY SSF46894 137 231 7.09E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS07720 2fdda09dacd6ead030575e017c754f92 233 Pfam PF00072 Response regulator receiver domain 5 113 2.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS00655 08014ee27704078ed7900a31731a25d2 444 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 8 428 1.5E-139 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR56_RS00655 08014ee27704078ed7900a31731a25d2 444 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 8 428 1.5E-139 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS00655 08014ee27704078ed7900a31731a25d2 444 Pfam PF02378 Phosphotransferase system, EIIC 25 354 3.3E-61 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS00655 08014ee27704078ed7900a31731a25d2 444 PIRSF PIRSF006351 1 435 1.2E-145 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS10790 6bbe3c6cd95f2666f4cd02fa0f954054 258 Pfam PF01226 Formate/nitrite transporter 4 250 4.8E-63 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CWR56_RS10790 6bbe3c6cd95f2666f4cd02fa0f954054 258 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CWR56_RS10790 6bbe3c6cd95f2666f4cd02fa0f954054 258 Gene3D G3DSA:1.20.1080.10 1 258 2.2E-70 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWR56_RS06415 7d98d0e831b3874cad5e34fadd2e27cf 86 Gene3D G3DSA:1.25.40.200 5 85 4.6E-4 T 29-03-2018 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Gene3D G3DSA:1.10.10.350 390 492 4.0E-24 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 8.2E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 8.2E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 216 224 8.2E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 210 8.2E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 8.2E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 486 9.0E-181 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Gene3D G3DSA:3.40.50.620 3 133 8.0E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 327 1.3E-114 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 SUPERFAMILY SSF48163 321 487 4.84E-39 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Gene3D G3DSA:1.10.1160.10 253 337 3.6E-35 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 SUPERFAMILY SSF52374 3 317 3.22E-111 T 29-03-2018 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Gene3D G3DSA:1.10.8.70 340 388 1.8E-5 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Gene3D G3DSA:3.40.50.620 134 252 1.4E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS18980 eaa5cbf9f576e28796eca769fef4182b 493 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 489 32.911 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR56_RS14885 449fba1064c424e5ad8746605ff7ffcf 209 SUPERFAMILY SSF53920 144 208 6.54E-6 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS14620 a1059251c1fa361b68ffcaa0d98a6898 337 SUPERFAMILY SSF81345 7 334 2.88E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CWR56_RS14620 a1059251c1fa361b68ffcaa0d98a6898 337 Pfam PF01032 FecCD transport family 21 334 1.9E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR56_RS14620 a1059251c1fa361b68ffcaa0d98a6898 337 Gene3D G3DSA:1.10.3470.10 5 337 3.4E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 Hamap MF_01237 N-acetylneuraminate lyase [nanA]. 6 293 50.577 T 29-03-2018 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581|Reactome: R-HSA-4085001 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 43 60 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 SMART SM01130 5 293 1.2E-76 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 PIRSF PIRSF001365 1 292 5.8E-63 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 SUPERFAMILY SSF51569 5 291 8.16E-77 T 29-03-2018 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 3.4E-22 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 3.4E-22 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 3.4E-22 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 3.4E-22 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 Pfam PF00701 Dihydrodipicolinate synthetase family 6 288 2.6E-94 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 Gene3D G3DSA:3.20.20.70 3 293 1.6E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10840 9e5d865a6ab56280f3f541329b45641e 293 TIGRFAM TIGR00683 nanA: N-acetylneuraminate lyase 6 291 3.4E-133 T 29-03-2018 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581|Reactome: R-HSA-4085001 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Gene3D G3DSA:1.10.1790.10 163 269 1.3E-9 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Gene3D G3DSA:3.40.930.10 490 632 6.3E-27 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 496 631 4.2E-24 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Gene3D G3DSA:3.40.50.2300 396 480 3.3E-8 T 29-03-2018 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Gene3D G3DSA:1.10.10.10 1 62 1.4E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Gene3D G3DSA:1.10.10.10 74 133 6.8E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Pfam PF00874 PRD domain 182 262 7.1E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Pfam PF00874 PRD domain 294 382 2.2E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Gene3D G3DSA:1.10.1790.10 283 384 1.2E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 SUPERFAMILY SSF63520 283 387 5.89E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 SUPERFAMILY SSF55804 492 630 9.03E-28 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 SUPERFAMILY SSF63520 177 265 2.35E-9 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Pfam PF05043 Mga helix-turn-helix domain 79 149 1.2E-7 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS15400 97df48e9232cccd44e16f96c91436040 637 Pfam PF08279 HTH domain 10 58 6.9E-8 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS12810 ef07846c1b91c0662f4efcf3bf03be1c 227 Gene3D G3DSA:3.40.50.300 1 227 3.8E-67 T 29-03-2018 CWR56_RS12810 ef07846c1b91c0662f4efcf3bf03be1c 227 SMART SM00382 32 218 3.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS12810 ef07846c1b91c0662f4efcf3bf03be1c 227 SUPERFAMILY SSF52540 3 225 2.05E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12810 ef07846c1b91c0662f4efcf3bf03be1c 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS12810 ef07846c1b91c0662f4efcf3bf03be1c 227 Pfam PF00005 ABC transporter 23 169 1.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 111 358 6.2E-44 T 29-03-2018 IPR000477 Reverse transcriptase domain CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 Gene3D G3DSA:3.40.1800.10 531 608 2.2E-9 T 29-03-2018 CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 436 7.4E-106 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 SMART SM00507 540 594 4.2E-5 T 29-03-2018 IPR003615 HNH nuclease CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 Gene3D G3DSA:3.30.70.270 127 358 3.5E-33 T 29-03-2018 CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 SUPERFAMILY SSF56672 295 371 3.24E-51 T 29-03-2018 CWR56_RS11095 727f51622e66c7af1b51ea2b7e8fc66e 636 SUPERFAMILY SSF56672 48 263 3.24E-51 T 29-03-2018 CWR56_RS11255 0f10479710c648f6dd5642e416f554d1 246 Gene3D G3DSA:3.90.190.10 10 188 1.8E-26 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CWR56_RS11255 0f10479710c648f6dd5642e416f554d1 246 Pfam PF13350 Tyrosine phosphatase family 2 246 4.4E-64 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CWR56_RS11255 0f10479710c648f6dd5642e416f554d1 246 SUPERFAMILY SSF52799 3 245 1.9E-51 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CWR56_RS14185 328a446e14716698b9cc3ebb99e9c208 626 Pfam PF04122 Putative cell wall binding repeat 2 531 597 4.8E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14185 328a446e14716698b9cc3ebb99e9c208 626 Pfam PF04122 Putative cell wall binding repeat 2 325 412 8.0E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14185 328a446e14716698b9cc3ebb99e9c208 626 Pfam PF04122 Putative cell wall binding repeat 2 427 514 3.3E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS12230 2db8059e54a3195d6590c8b4bf3844a5 419 SUPERFAMILY SSF103473 12 413 4.45E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS12230 2db8059e54a3195d6590c8b4bf3844a5 419 Gene3D G3DSA:1.20.1250.20 213 418 2.1E-18 T 29-03-2018 CWR56_RS12230 2db8059e54a3195d6590c8b4bf3844a5 419 Pfam PF07690 Major Facilitator Superfamily 34 361 9.8E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS12230 2db8059e54a3195d6590c8b4bf3844a5 419 Gene3D G3DSA:1.20.1250.20 13 212 2.2E-26 T 29-03-2018 CWR56_RS11490 901c12bf2ffe0a6504f3f98770bc1fbe 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 249 3.2E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS11490 901c12bf2ffe0a6504f3f98770bc1fbe 263 Gene3D G3DSA:1.10.3720.10 42 261 8.0E-36 T 29-03-2018 CWR56_RS11490 901c12bf2ffe0a6504f3f98770bc1fbe 263 SUPERFAMILY SSF161098 2 255 7.57E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS18890 0ff24a1030a0f76b06c706cba450f027 548 Gene3D G3DSA:2.60.120.200 338 539 2.0E-33 T 29-03-2018 CWR56_RS18890 0ff24a1030a0f76b06c706cba450f027 548 SUPERFAMILY SSF75005 2 316 2.57E-87 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR56_RS18890 0ff24a1030a0f76b06c706cba450f027 548 SUPERFAMILY SSF49899 340 539 5.94E-50 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWR56_RS18890 0ff24a1030a0f76b06c706cba450f027 548 Pfam PF04616 Glycosyl hydrolases family 43 2 313 5.8E-86 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CWR56_RS18890 0ff24a1030a0f76b06c706cba450f027 548 Gene3D G3DSA:2.115.10.20 1 337 1.0E-72 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR56_RS03745 712e23e879f12eca99fe53aa5298d915 142 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 137 1.5E-64 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CWR56_RS03745 712e23e879f12eca99fe53aa5298d915 142 SUPERFAMILY SSF55874 24 135 1.14E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03745 712e23e879f12eca99fe53aa5298d915 142 Pfam PF13581 Histidine kinase-like ATPase domain 14 136 3.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03745 712e23e879f12eca99fe53aa5298d915 142 Gene3D G3DSA:3.30.565.10 1 141 5.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03745 712e23e879f12eca99fe53aa5298d915 142 SMART SM00387 35 140 5.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS03745 712e23e879f12eca99fe53aa5298d915 142 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 35.719 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CWR56_RS07185 cd581ede49fda6b068b96c9622479026 75 Gene3D G3DSA:2.30.30.90 1 75 6.3E-14 T 29-03-2018 CWR56_RS07185 cd581ede49fda6b068b96c9622479026 75 SUPERFAMILY SSF50037 4 73 3.66E-14 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR56_RS07185 cd581ede49fda6b068b96c9622479026 75 Pfam PF04023 FeoA domain 3 73 6.1E-14 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS07185 cd581ede49fda6b068b96c9622479026 75 SMART SM00899 2 74 4.7E-15 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 Gene3D G3DSA:1.25.40.10 352 462 8.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 Gene3D G3DSA:1.25.40.10 43 320 4.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 SUPERFAMILY SSF48452 173 257 8.35E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 SUPERFAMILY SSF48452 349 423 8.35E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 SUPERFAMILY SSF48452 81 132 8.35E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 Gene3D G3DSA:3.30.70.270 463 632 3.1E-35 T 29-03-2018 CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 SMART SM00267 453 632 4.4E-36 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 Pfam PF00990 Diguanylate cyclase, GGDEF domain 467 628 2.9E-34 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 460 630 7.4E-33 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS12025 19937a42dcc7cbbac2f97d50cbab4513 632 SUPERFAMILY SSF55073 469 631 1.33E-29 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Gene3D G3DSA:3.90.400.10 104 168 7.5E-28 T 29-03-2018 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Gene3D G3DSA:3.20.20.470 169 344 1.5E-36 T 29-03-2018 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Gene3D G3DSA:3.20.20.470 1 103 6.5E-36 T 29-03-2018 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Gene3D G3DSA:2.60.40.1180 478 555 4.2E-15 T 29-03-2018 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 SUPERFAMILY SSF51011 477 553 1.23E-13 T 29-03-2018 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Pfam PF00128 Alpha amylase, catalytic domain 27 375 8.4E-124 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 SUPERFAMILY SSF51445 3 474 1.34E-147 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 477 547 1.0E-7 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 Gene3D G3DSA:3.20.20.80 345 470 1.1E-20 T 29-03-2018 CWR56_RS15440 a407d151dc5129bcca1393cb4bde969d 555 SMART SM00642 12 418 6.7E-152 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS10325 e3cb46d12b35401889cc782963ed7a1a 214 SUPERFAMILY SSF47413 8 70 6.76E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS10325 e3cb46d12b35401889cc782963ed7a1a 214 Pfam PF01381 Helix-turn-helix 14 68 8.5E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10325 e3cb46d12b35401889cc782963ed7a1a 214 Gene3D G3DSA:1.10.260.40 9 159 5.2E-16 T 29-03-2018 CWR56_RS10325 e3cb46d12b35401889cc782963ed7a1a 214 SMART SM00530 13 68 1.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10325 e3cb46d12b35401889cc782963ed7a1a 214 Pfam PF06803 Protein of unknown function (DUF1232) 171 203 2.8E-9 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CWR56_RS16125 818c903ab55e37a241f8cb0fe0db16f5 167 Gene3D G3DSA:3.40.50.360 8 110 5.2E-8 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS16125 818c903ab55e37a241f8cb0fe0db16f5 167 SUPERFAMILY SSF52218 26 95 1.22E-7 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 Gene3D G3DSA:3.40.1390.30 1 127 4.3E-39 T 29-03-2018 CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 Gene3D G3DSA:3.40.1390.30 221 358 1.3E-11 T 29-03-2018 CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 SUPERFAMILY SSF102705 1 363 2.09E-125 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 346 4.5E-84 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 PIRSF PIRSF037489 1 365 3.0E-138 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 356 4.3E-70 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR56_RS06855 ad12fd5e9919968b1416cce60a50a0ef 365 Gene3D G3DSA:3.30.70.120 130 220 1.5E-37 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.1E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.1E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 Gene3D G3DSA:3.40.50.1360 65 252 7.0E-41 T 29-03-2018 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 SMART SM01134 73 233 8.7E-68 T 29-03-2018 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 SUPERFAMILY SSF100950 75 233 1.12E-32 T 29-03-2018 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 SMART SM00420 6 58 5.0E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 Pfam PF00455 DeoR C terminal sensor domain 75 231 6.2E-50 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 SUPERFAMILY SSF46785 5 59 3.46E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 Gene3D G3DSA:1.10.10.10 2 59 4.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03600 d71b53979b1756c9b885db3645eb6025 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 5.5E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS17950 c1da66eed631b0a8f3f54ac67ce6ec21 304 SUPERFAMILY SSF55469 195 218 1.96E-5 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS17950 c1da66eed631b0a8f3f54ac67ce6ec21 304 Gene3D G3DSA:3.40.109.30 184 263 2.2E-6 T 29-03-2018 CWR56_RS17950 c1da66eed631b0a8f3f54ac67ce6ec21 304 SUPERFAMILY SSF55469 3 173 6.67E-20 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS17950 c1da66eed631b0a8f3f54ac67ce6ec21 304 Pfam PF14512 Putative TM nitroreductase 147 252 9.6E-16 T 29-03-2018 IPR029478 Putative nitroreductase TM1586 CWR56_RS17950 c1da66eed631b0a8f3f54ac67ce6ec21 304 Pfam PF14512 Putative TM nitroreductase 2 114 2.5E-23 T 29-03-2018 IPR029478 Putative nitroreductase TM1586 CWR56_RS17950 c1da66eed631b0a8f3f54ac67ce6ec21 304 Gene3D G3DSA:3.40.109.10 1 183 4.8E-22 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS15335 dd181b4dfe3ce2a7abb68977fd51cf8b 142 Gene3D G3DSA:1.20.120.330 2 142 1.2E-4 T 29-03-2018 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 6.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 Gene3D G3DSA:1.10.357.10 70 212 5.2E-15 T 29-03-2018 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 SUPERFAMILY SSF46689 6 75 5.13E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 Gene3D G3DSA:1.10.260.40 40 69 1.6E-7 T 29-03-2018 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 Gene3D G3DSA:1.10.10.60 1 39 4.1E-11 T 29-03-2018 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 8.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS02120 314b73b4e7f7b3562b6b5929611a0628 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 8.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS12235 412178014786af352e1459384ecdb3f8 402 Pfam PF00155 Aminotransferase class I and II 46 387 6.0E-39 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS12235 412178014786af352e1459384ecdb3f8 402 Gene3D G3DSA:3.40.640.10 47 299 4.4E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS12235 412178014786af352e1459384ecdb3f8 402 SUPERFAMILY SSF53383 5 395 2.95E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12235 412178014786af352e1459384ecdb3f8 402 Gene3D G3DSA:3.90.1150.10 300 397 3.5E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 Gene3D G3DSA:3.90.400.10 120 167 6.0E-28 T 29-03-2018 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 SUPERFAMILY SSF51445 3 471 6.55E-138 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 SUPERFAMILY SSF51011 481 552 2.97E-8 T 29-03-2018 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 Pfam PF00128 Alpha amylase, catalytic domain 28 375 2.9E-98 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 PRINTS PR00110 Alpha-amylase signature 191 202 1.3E-5 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 PRINTS PR00110 Alpha-amylase signature 92 103 1.3E-5 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 PRINTS PR00110 Alpha-amylase signature 318 330 1.3E-5 T 29-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 Gene3D G3DSA:3.20.20.80 342 471 1.1E-20 T 29-03-2018 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 Gene3D G3DSA:3.20.20.80 2 119 1.5E-48 T 29-03-2018 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 Gene3D G3DSA:3.20.20.470 168 341 2.5E-27 T 29-03-2018 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 Gene3D G3DSA:2.60.40.1180 484 554 2.3E-8 T 29-03-2018 CWR56_RS02150 b83c47f1f2ce10a1746fb136df164cf2 554 SMART SM00642 13 417 2.4E-125 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 Gene3D G3DSA:3.50.50.60 317 387 1.9E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 Gene3D G3DSA:3.50.50.60 4 239 6.0E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 SUPERFAMILY SSF56425 219 330 2.09E-33 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 Pfam PF00890 FAD binding domain 6 369 2.8E-81 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 Gene3D G3DSA:3.90.700.10 240 316 1.2E-28 T 29-03-2018 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 354 1.1E-6 T 29-03-2018 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-6 T 29-03-2018 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 SUPERFAMILY SSF51905 333 401 7.67E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS11785 57b95bbf96557dd6c2b8169729713219 433 SUPERFAMILY SSF51905 3 236 7.67E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS16700 8cc7387fd08a619e8782699069a7edc5 209 Pfam PF12654 Domain of unknown function (DUF3786) 25 200 2.9E-54 T 29-03-2018 IPR024264 Domain of unknown function DUF3786 CWR56_RS14355 41392f640f5868ac1b13b2a8dbe57e7d 399 SUPERFAMILY SSF53383 17 392 4.3E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS14355 41392f640f5868ac1b13b2a8dbe57e7d 399 Pfam PF00155 Aminotransferase class I and II 37 382 5.0E-52 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS14355 41392f640f5868ac1b13b2a8dbe57e7d 399 Gene3D G3DSA:3.90.1150.10 305 396 1.0E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS14355 41392f640f5868ac1b13b2a8dbe57e7d 399 Gene3D G3DSA:3.40.640.10 52 304 3.5E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS14355 41392f640f5868ac1b13b2a8dbe57e7d 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWR56_RS18850 a5022403ae5c8408df0c5669d88789e3 341 Hamap MF_00602 Protein-arginine kinase [mcsB]. 1 330 32.338 T 29-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CWR56_RS18850 a5022403ae5c8408df0c5669d88789e3 341 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 34 234 1.4E-65 T 29-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CWR56_RS18850 a5022403ae5c8408df0c5669d88789e3 341 SUPERFAMILY SSF55931 3 249 1.09E-79 T 29-03-2018 CWR56_RS18850 a5022403ae5c8408df0c5669d88789e3 341 Gene3D G3DSA:3.30.590.10 1 236 1.2E-76 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CWR56_RS04235 f50b5bc5542d412e58e679299f2d9a88 434 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 421 2.8E-87 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR56_RS04235 f50b5bc5542d412e58e679299f2d9a88 434 PIRSF PIRSF006351 6 428 5.5E-117 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS04235 f50b5bc5542d412e58e679299f2d9a88 434 Pfam PF02378 Phosphotransferase system, EIIC 35 348 2.0E-39 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS18885 5a15633a8e37ae2ef10a37cda58c6918 388 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 52 299 6.3E-10 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CWR56_RS18885 5a15633a8e37ae2ef10a37cda58c6918 388 SUPERFAMILY SSF51445 2 386 4.98E-86 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS18885 5a15633a8e37ae2ef10a37cda58c6918 388 Gene3D G3DSA:3.20.20.80 1 388 6.6E-61 T 29-03-2018 CWR56_RS05250 f1ed99145acfcfff264ce06e061e4c78 360 SUPERFAMILY SSF54001 66 182 2.22E-13 T 29-03-2018 CWR56_RS05250 f1ed99145acfcfff264ce06e061e4c78 360 Pfam PF01841 Transglutaminase-like superfamily 76 161 1.3E-6 T 29-03-2018 IPR002931 Transglutaminase-like CWR56_RS05085 3a37c1ddb50422d16f61f91c09aebacd 289 Gene3D G3DSA:3.40.109.10 1 195 3.4E-19 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS05085 3a37c1ddb50422d16f61f91c09aebacd 289 Pfam PF14512 Putative TM nitroreductase 3 254 2.3E-36 T 29-03-2018 IPR029478 Putative nitroreductase TM1586 CWR56_RS05085 3a37c1ddb50422d16f61f91c09aebacd 289 SUPERFAMILY SSF55469 195 287 8.77E-8 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS05085 3a37c1ddb50422d16f61f91c09aebacd 289 Gene3D G3DSA:3.40.109.30 196 266 1.3E-6 T 29-03-2018 CWR56_RS05085 3a37c1ddb50422d16f61f91c09aebacd 289 SUPERFAMILY SSF55469 4 146 7.2E-22 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS06975 66ab8171a2701539ff0bd4cfdbe8f6a6 236 Gene3D G3DSA:3.60.160.10 9 217 2.1E-34 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWR56_RS06975 66ab8171a2701539ff0bd4cfdbe8f6a6 236 SUPERFAMILY SSF51219 5 214 1.07E-38 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CWR56_RS06975 66ab8171a2701539ff0bd4cfdbe8f6a6 236 Pfam PF01987 Mitochondrial biogenesis AIM24 17 206 1.4E-19 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 Pfam PF00072 Response regulator receiver domain 6 116 9.6E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 SMART SM00448 2 116 9.3E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 Gene3D G3DSA:3.40.50.2300 1 129 3.0E-19 T 29-03-2018 CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 SMART SM00850 137 228 9.6E-20 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 Gene3D G3DSA:2.40.50.40 130 196 4.7E-19 T 29-03-2018 CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 SUPERFAMILY SSF52172 4 167 2.28E-19 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS16745 dc613be380e0f6bd2fe57eae4258042e 236 Pfam PF04397 LytTr DNA-binding domain 142 226 4.4E-18 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 Gene3D G3DSA:3.40.50.300 165 441 1.1E-69 T 29-03-2018 CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 8 437 2.5E-180 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 SUPERFAMILY SSF48024 6 118 3.79E-39 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 SUPERFAMILY SSF52540 181 430 6.25E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 Gene3D G3DSA:1.10.860.10 1 149 5.4E-48 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 Pfam PF00772 DnaB-like helicase N terminal domain 8 109 1.2E-36 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR56_RS18310 b0296680c4251e88588776a8223c522e 442 Pfam PF03796 DnaB-like helicase C terminal domain 183 436 3.1E-114 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWR56_RS07460 3b63d93bf9cb2c45933b102e6e50a0d0 265 Pfam PF03990 Domain of unknown function (DUF348) 36 74 1.5E-12 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CWR56_RS07460 3b63d93bf9cb2c45933b102e6e50a0d0 265 Pfam PF07501 G5 domain 91 164 4.8E-21 T 29-03-2018 IPR011098 G5 domain CWR56_RS07460 3b63d93bf9cb2c45933b102e6e50a0d0 265 SMART SM01208 87 165 8.4E-26 T 29-03-2018 IPR011098 G5 domain CWR56_RS07460 3b63d93bf9cb2c45933b102e6e50a0d0 265 Gene3D G3DSA:2.40.40.10 82 262 8.9E-40 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CWR56_RS07460 3b63d93bf9cb2c45933b102e6e50a0d0 265 SUPERFAMILY SSF50685 205 255 1.19E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CWR56_RS07460 3b63d93bf9cb2c45933b102e6e50a0d0 265 Pfam PF06725 3D domain 205 264 2.3E-18 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 SUPERFAMILY SSF52096 10 192 4.97E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 Gene3D G3DSA:3.90.226.10 2 194 2.2E-45 T 29-03-2018 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 9.0E-108 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.829 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 29-03-2018 IPR018215 ClpP, Ser active site CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 Pfam PF00574 Clp protease 13 192 8.7E-90 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 7.9E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 7.9E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 7.9E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 7.9E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS16620 8851a01389eef0f08ad97739a980bec8 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 7.9E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR56_RS04580 ded60a6ff7e156a88368ca4d4c27f9e4 87 Pfam PF12674 Putative zinc ribbon domain 6 87 2.6E-34 T 29-03-2018 IPR025868 Putative zinc ribbon domain CWR56_RS00770 cffeb2676a29a6370d3b472cb137a3b2 835 Pfam PF02687 FtsX-like permease family 285 383 5.2E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS16130 ee3bd5fb4cb4e3642f8d2e8b3858f04d 216 SUPERFAMILY SSF52218 1 137 2.48E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS16130 ee3bd5fb4cb4e3642f8d2e8b3858f04d 216 Gene3D G3DSA:3.40.50.360 1 216 1.2E-13 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 Gene3D G3DSA:2.30.30.60 133 183 6.4E-17 T 29-03-2018 CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 SUPERFAMILY SSF50182 118 183 5.56E-18 T 29-03-2018 IPR010920 LSM domain CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 Gene3D G3DSA:3.30.70.100 184 276 8.5E-26 T 29-03-2018 CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 147 181 - T 29-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 SUPERFAMILY SSF82689 185 275 2.62E-25 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 SUPERFAMILY SSF82861 32 116 4.71E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 Pfam PF00924 Mechanosensitive ion channel 77 271 5.9E-55 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CWR56_RS18545 25e917df04eb961726d58f2a4ce0ce4d 293 Pfam PF05552 Conserved TM helix 21 65 2.9E-12 T 29-03-2018 IPR008910 Conserved TM helix CWR56_RS02770 f5a5e9bc44086a81baf5c0bd1c5bd52f 437 SUPERFAMILY SSF52402 10 125 4.97E-31 T 29-03-2018 CWR56_RS02770 f5a5e9bc44086a81baf5c0bd1c5bd52f 437 SUPERFAMILY SSF52402 153 235 4.97E-31 T 29-03-2018 CWR56_RS02770 f5a5e9bc44086a81baf5c0bd1c5bd52f 437 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 238 7.2E-8 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CWR56_RS02770 f5a5e9bc44086a81baf5c0bd1c5bd52f 437 Pfam PF11922 Domain of unknown function (DUF3440) 241 423 9.7E-85 T 29-03-2018 IPR021845 Protein of unknown function DUF3440 CWR56_RS02770 f5a5e9bc44086a81baf5c0bd1c5bd52f 437 Gene3D G3DSA:3.40.50.620 5 241 2.6E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 Gene3D G3DSA:1.10.560.10 61 183 1.4E-25 T 29-03-2018 IPR027413 GroEL-like equatorial domain CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.4E-101 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 7.5E-253 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 Gene3D G3DSA:3.50.7.10 184 370 5.0E-96 T 29-03-2018 IPR027409 GroEL-like apical domain CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 Gene3D G3DSA:1.10.560.10 371 515 2.4E-26 T 29-03-2018 IPR027413 GroEL-like equatorial domain CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 PRINTS PR00298 60kDa chaperonin signature 26 52 4.7E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 PRINTS PR00298 60kDa chaperonin signature 348 373 4.7E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 PRINTS PR00298 60kDa chaperonin signature 396 417 4.7E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 PRINTS PR00298 60kDa chaperonin signature 266 289 4.7E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 PRINTS PR00298 60kDa chaperonin signature 82 109 4.7E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 41.319 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 SUPERFAMILY SSF52029 182 374 1.0E-82 T 29-03-2018 IPR027409 GroEL-like apical domain CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 SUPERFAMILY SSF48592 404 520 5.42E-78 T 29-03-2018 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 SUPERFAMILY SSF48592 5 133 5.42E-78 T 29-03-2018 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR56_RS00965 7355bc13eb29bef5cce5094a0a163afe 542 SUPERFAMILY SSF54849 137 204 6.64E-26 T 29-03-2018 CWR56_RS15855 f2ac1910016433369cd88745bf5b5ce3 154 SUPERFAMILY SSF55729 1 139 4.4E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS15855 f2ac1910016433369cd88745bf5b5ce3 154 Pfam PF00583 Acetyltransferase (GNAT) family 27 131 2.4E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS15855 f2ac1910016433369cd88745bf5b5ce3 154 Gene3D G3DSA:3.40.630.30 2 154 2.2E-16 T 29-03-2018 CWR56_RS18065 d3e346bbe88a1f7e209fbe060c9b6edf 305 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 90 298 5.0E-67 T 29-03-2018 IPR018728 Domain of unknown function DUF2268 CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 SUPERFAMILY SSF51182 59 187 2.53E-32 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 Pfam PF01381 Helix-turn-helix 12 66 9.8E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 SUPERFAMILY SSF47413 3 73 1.83E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 Gene3D G3DSA:1.10.260.40 3 81 2.1E-14 T 29-03-2018 CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 Pfam PF07883 Cupin domain 123 180 3.1E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 Gene3D G3DSA:2.60.120.10 82 187 5.5E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS07830 37a836cdffe669848df80d365f8c4e49 187 SMART SM00530 11 66 8.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS18555 f410a7889e3849cd49ceec9c6c61bb00 151 Pfam PF14437 MafB19-like deaminase 5 148 4.3E-40 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CWR56_RS18555 f410a7889e3849cd49ceec9c6c61bb00 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR56_RS18555 f410a7889e3849cd49ceec9c6c61bb00 151 SUPERFAMILY SSF53927 5 149 3.01E-46 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS18555 f410a7889e3849cd49ceec9c6c61bb00 151 Gene3D G3DSA:3.40.140.10 1 151 1.5E-42 T 29-03-2018 CWR56_RS18555 f410a7889e3849cd49ceec9c6c61bb00 151 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 148 39.336 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CWR56_RS04840 0eb556ada76ba5c2f07866734bf0f4fb 155 SUPERFAMILY SSF55826 5 152 1.44E-36 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS04840 0eb556ada76ba5c2f07866734bf0f4fb 155 Pfam PF04073 Aminoacyl-tRNA editing domain 26 142 2.0E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS04840 0eb556ada76ba5c2f07866734bf0f4fb 155 Gene3D G3DSA:3.90.960.10 2 155 5.1E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS14610 1199bd056f6c7bb3012c1072008c0b8d 260 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS14610 1199bd056f6c7bb3012c1072008c0b8d 260 SMART SM00382 28 217 4.2E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14610 1199bd056f6c7bb3012c1072008c0b8d 260 Gene3D G3DSA:3.40.50.300 1 253 5.6E-66 T 29-03-2018 CWR56_RS14610 1199bd056f6c7bb3012c1072008c0b8d 260 Pfam PF00005 ABC transporter 20 167 2.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS14610 1199bd056f6c7bb3012c1072008c0b8d 260 SUPERFAMILY SSF52540 4 232 3.73E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 SUPERFAMILY SSF52540 26 265 8.44E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 241 250 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 Gene3D G3DSA:1.10.8.60 200 306 5.7E-22 T 29-03-2018 CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 Gene3D G3DSA:3.40.50.300 20 199 3.0E-27 T 29-03-2018 CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 Gene3D G3DSA:1.10.10.60 307 345 1.1E-13 T 29-03-2018 CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 SUPERFAMILY SSF46689 241 344 9.73E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 Pfam PF02954 Bacterial regulatory protein, Fis family 303 344 7.2E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 SMART SM00382 47 191 4.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS10040 4da260e8afc6dba42196ebc4112914a8 346 Pfam PF00158 Sigma-54 interaction domain 27 194 1.6E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS08420 2be9144347c4de9d402abfdee5a74afb 281 SMART SM00382 26 205 5.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS08420 2be9144347c4de9d402abfdee5a74afb 281 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS08420 2be9144347c4de9d402abfdee5a74afb 281 Gene3D G3DSA:3.40.50.300 1 257 1.7E-58 T 29-03-2018 CWR56_RS08420 2be9144347c4de9d402abfdee5a74afb 281 SUPERFAMILY SSF52540 2 226 6.41E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08420 2be9144347c4de9d402abfdee5a74afb 281 Pfam PF00005 ABC transporter 17 157 3.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS00825 0e59e3d04623c8613d4766be3295ac6f 217 Gene3D G3DSA:2.60.120.10 10 199 4.8E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS00825 0e59e3d04623c8613d4766be3295ac6f 217 SUPERFAMILY SSF51206 18 129 2.09E-14 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CWR56_RS00825 0e59e3d04623c8613d4766be3295ac6f 217 Pfam PF00027 Cyclic nucleotide-binding domain 23 107 8.5E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS13620 accdc3063d4ade2380be0d89d2b52ec4 175 SUPERFAMILY SSF53271 8 171 7.74E-57 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS13620 accdc3063d4ade2380be0d89d2b52ec4 175 Pfam PF00156 Phosphoribosyl transferase domain 8 158 4.1E-26 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS13620 accdc3063d4ade2380be0d89d2b52ec4 175 Gene3D G3DSA:3.40.50.2020 3 175 3.0E-45 T 29-03-2018 CWR56_RS13620 accdc3063d4ade2380be0d89d2b52ec4 175 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 4.3E-70 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 158 175 1.8E-32 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 13 20 1.8E-32 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 57 65 1.8E-32 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 26 47 1.8E-32 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 114 128 1.8E-32 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 83 100 1.8E-32 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 SUPERFAMILY SSF53613 12 252 5.14E-56 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 5 250 1.4E-79 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 Pfam PF02110 Hydroxyethylthiazole kinase family 5 248 3.8E-77 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 Gene3D G3DSA:3.40.1190.20 1 262 6.0E-54 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 PIRSF PIRSF000513 1 261 4.5E-83 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS07600 c3d4ec71c4bd93982618720f19c00b5c 262 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 7 253 29.858 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR56_RS02060 8d6c7a293dcb8fdda5bd97ceaf41e678 469 PIRSF PIRSF004729 9 460 7.6E-150 T 29-03-2018 IPR006230 Protein MutL CWR56_RS02060 8d6c7a293dcb8fdda5bd97ceaf41e678 469 TIGRFAM TIGR01319 glmL_fam: conserved hypothetical protein 17 456 9.5E-83 T 29-03-2018 IPR006230 Protein MutL CWR56_RS02060 8d6c7a293dcb8fdda5bd97ceaf41e678 469 Pfam PF13941 MutL protein 12 457 3.0E-165 T 29-03-2018 IPR006230 Protein MutL CWR56_RS02060 8d6c7a293dcb8fdda5bd97ceaf41e678 469 Gene3D G3DSA:3.30.420.40 12 294 0.0023 T 29-03-2018 CWR56_RS15360 0d2ec2fc82ca0aaa60902d5c46851844 289 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 283 1.6E-98 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS15360 0d2ec2fc82ca0aaa60902d5c46851844 289 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 282 6.1E-102 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS15360 0d2ec2fc82ca0aaa60902d5c46851844 289 PIRSF PIRSF001359 1 283 7.1E-106 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS15360 0d2ec2fc82ca0aaa60902d5c46851844 289 Gene3D G3DSA:3.20.20.70 1 285 4.2E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS15360 0d2ec2fc82ca0aaa60902d5c46851844 289 SUPERFAMILY SSF51569 3 283 7.03E-101 T 29-03-2018 CWR56_RS15360 0d2ec2fc82ca0aaa60902d5c46851844 289 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 13 166 9.5E-68 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 Gene3D G3DSA:3.30.160.20 13 75 1.9E-29 T 29-03-2018 CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 166 35.231 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 Gene3D G3DSA:3.30.230.10 79 169 5.8E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 Pfam PF00333 Ribosomal protein S5, N-terminal domain 14 78 2.6E-30 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 SUPERFAMILY SSF54211 83 162 7.33E-26 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 SUPERFAMILY SSF54768 12 79 8.27E-24 T 29-03-2018 CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 ProSitePatterns PS00585 Ribosomal protein S5 signature. 31 63 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CWR56_RS00170 3d1b87e41521539ed29af02bd4368438 169 Pfam PF03719 Ribosomal protein S5, C-terminal domain 90 160 1.5E-29 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR56_RS03375 1e8df094ca4be5354396f5740332be1e 227 Pfam PF06912 Protein of unknown function (DUF1275) 15 213 1.4E-49 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 CWR56_RS09790 5d84fafa754c96aa7365728e221db561 155 Pfam PF11188 Protein of unknown function (DUF2975) 46 155 1.9E-10 T 29-03-2018 IPR021354 Protein of unknown function DUF2975 CWR56_RS02510 051f0a58a724786c287155fdfc00f92d 259 Pfam PF06161 Protein of unknown function (DUF975) 1 240 3.9E-37 T 29-03-2018 IPR010380 Protein of unknown function DUF975 CWR56_RS17490 b72e79ffed0384f2478614afb60944fe 175 Gene3D G3DSA:3.30.700.10 10 174 5.3E-5 T 29-03-2018 CWR56_RS17490 b72e79ffed0384f2478614afb60944fe 175 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 28 2.2E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17490 b72e79ffed0384f2478614afb60944fe 175 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17490 b72e79ffed0384f2478614afb60944fe 175 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 26 8.8E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS13935 e34a2f7dd670e8398910ab05ab3ab7a4 165 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 44 2.4E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS13935 e34a2f7dd670e8398910ab05ab3ab7a4 165 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 85 119 6.5E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS13935 e34a2f7dd670e8398910ab05ab3ab7a4 165 SUPERFAMILY SSF51161 4 160 1.94E-47 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS13935 e34a2f7dd670e8398910ab05ab3ab7a4 165 Gene3D G3DSA:2.160.10.10 1 165 1.8E-45 T 29-03-2018 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 Gene3D G3DSA:3.40.50.300 1 208 3.2E-32 T 29-03-2018 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 Pfam PF02421 Ferrous iron transport protein B 2 154 2.3E-62 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 Pfam PF07664 Ferrous iron transport protein B C terminus 381 432 5.4E-20 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 Pfam PF07670 Nucleoside recognition 437 556 5.7E-28 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 Pfam PF07670 Nucleoside recognition 278 368 4.2E-12 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 182 553 2.3E-115 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 Pfam PF12669 Virus attachment protein p12 family 593 635 1.5E-6 T 29-03-2018 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 9.4E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 9.4E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS16465 4f77b82205a28e538a7c64c3c7033ae3 648 SUPERFAMILY SSF52540 2 162 5.97E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 Gene3D G3DSA:1.10.1740.10 301 384 1.1E-28 T 29-03-2018 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 7.6E-160 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 PIRSF PIRSF006205 1 384 5.7E-167 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 381 48.683 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 131 1.5E-45 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 SUPERFAMILY SSF69055 290 383 4.45E-32 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 Gene3D G3DSA:3.40.50.720 1 149 1.1E-52 T 29-03-2018 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 SUPERFAMILY SSF55347 125 263 4.9E-62 T 29-03-2018 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 145 228 3.7E-41 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 Pfam PF13288 DXP reductoisomerase C-terminal domain 260 376 5.9E-42 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CWR56_RS10255 335a1bd08fc50f1dde99f45ee4735111 384 SUPERFAMILY SSF51735 2 149 1.14E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS10500 0721bc72ef52a797068557db89f6a9b2 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 220 1.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS10500 0721bc72ef52a797068557db89f6a9b2 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 113 1.1E-26 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWR56_RS10500 0721bc72ef52a797068557db89f6a9b2 222 Gene3D G3DSA:1.10.3720.10 1 222 4.7E-45 T 29-03-2018 CWR56_RS10500 0721bc72ef52a797068557db89f6a9b2 222 SUPERFAMILY SSF161098 14 219 2.88E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS03370 2c1d0d5f8d6a4abe88ee4b7519315af6 196 Gene3D G3DSA:1.20.1170.10 25 196 4.0E-6 T 29-03-2018 CWR56_RS03370 2c1d0d5f8d6a4abe88ee4b7519315af6 196 SUPERFAMILY SSF102829 4 83 3.01E-13 T 29-03-2018 IPR007838 Cell division protein ZapA-like CWR56_RS03370 2c1d0d5f8d6a4abe88ee4b7519315af6 196 Pfam PF05164 Cell division protein ZapA 4 90 9.6E-11 T 29-03-2018 IPR007838 Cell division protein ZapA-like CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Pfam PF00158 Sigma-54 interaction domain 106 270 1.2E-45 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Gene3D G3DSA:3.40.50.510 550 696 3.0E-18 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Pfam PF00874 PRD domain 830 913 9.5E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Gene3D G3DSA:1.10.1790.10 815 918 5.1E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Gene3D G3DSA:1.10.10.10 2 72 5.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 SMART SM00382 129 282 1.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Gene3D G3DSA:3.40.50.300 90 361 5.7E-26 T 29-03-2018 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Gene3D G3DSA:1.10.1790.10 452 549 0.0022 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 SUPERFAMILY SSF52540 105 341 2.29E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 Pfam PF03610 PTS system fructose IIA component 566 632 5.7E-6 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 SUPERFAMILY SSF53062 566 677 2.09E-13 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 SUPERFAMILY SSF63520 814 915 1.2E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS16495 172559a615f242191d24b04319c4aabd 918 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 133 146 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 SUPERFAMILY SSF50249 2 137 2.4E-48 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PIRSF PIRSF002133 1 137 1.4E-48 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 2.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 2.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 2.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 2.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 2.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 2.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 1.1E-66 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 Gene3D G3DSA:2.40.50.140 1 140 1.6E-63 T 29-03-2018 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.662 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00060 544b45603f80339817ab72753f4c32db 140 Pfam PF00164 Ribosomal protein S12/S23 38 136 5.0E-39 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS18210 010f777941cd69f9ea16aced3e2b08f1 433 Pfam PF02378 Phosphotransferase system, EIIC 30 352 9.0E-55 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS18210 010f777941cd69f9ea16aced3e2b08f1 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 427 7.9E-116 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR56_RS18210 010f777941cd69f9ea16aced3e2b08f1 433 PIRSF PIRSF006351 1 432 1.8E-142 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 SUPERFAMILY SSF56235 2 225 1.2E-72 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 Gene3D G3DSA:3.60.20.10 2 231 3.7E-63 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 SUPERFAMILY SSF53271 238 450 8.88E-67 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 Gene3D G3DSA:3.40.50.2020 232 429 2.1E-33 T 29-03-2018 CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 443 1.7E-161 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 Pfam PF00156 Phosphoribosyl transferase domain 274 373 9.7E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 Pfam PF13537 Glutamine amidotransferase domain 83 198 3.0E-23 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 PIRSF PIRSF000485 1 454 1.6E-173 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWR56_RS01090 f56dc255914f90f4dccd4bc78c900a26 455 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 442 45.822 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWR56_RS02655 434703466c93b7b74c4f5d2994106c84 363 Pfam PF12784 PD-(D/E)XK nuclease family transposase 79 291 1.1E-30 T 29-03-2018 CWR56_RS02655 434703466c93b7b74c4f5d2994106c84 363 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 80 359 1.3E-20 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 SMART SM00902 518 577 4.6E-28 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 227 512 1.3E-98 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Gene3D G3DSA:4.10.260.20 520 584 4.4E-24 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 SUPERFAMILY SSF54292 3 89 4.68E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Gene3D G3DSA:3.10.20.30 2 121 5.9E-12 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 127 5.6E-20 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Gene3D G3DSA:3.30.70.20 129 161 0.012 T 29-03-2018 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 SMART SM00929 88 128 1.4E-22 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 SUPERFAMILY SSF53920 193 574 2.35E-131 T 29-03-2018 IPR009016 Iron hydrogenase CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Pfam PF02256 Iron hydrogenase small subunit 522 576 4.9E-24 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 SUPERFAMILY SSF54862 80 215 9.21E-38 T 29-03-2018 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Gene3D G3DSA:3.40.50.1780 310 435 9.5E-38 T 29-03-2018 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Gene3D G3DSA:3.40.50.1780 196 309 3.2E-34 T 29-03-2018 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Pfam PF00037 4Fe-4S binding domain 191 210 9.4E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 144 516 3.7E-157 T 29-03-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 81 2.2E-15 T 29-03-2018 CWR56_RS16960 56d4d902a276282380ff126c933f0dc8 593 Gene3D G3DSA:3.30.70.20 162 195 2.4E-10 T 29-03-2018 CWR56_RS02625 047e9f55e2f99bf60c5126ffa84be55e 334 Gene3D G3DSA:3.40.50.2300 47 165 1.5E-29 T 29-03-2018 CWR56_RS02625 047e9f55e2f99bf60c5126ffa84be55e 334 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 55 333 1.2E-52 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CWR56_RS02625 047e9f55e2f99bf60c5126ffa84be55e 334 Gene3D G3DSA:3.40.50.2300 166 334 3.5E-30 T 29-03-2018 CWR56_RS02625 047e9f55e2f99bf60c5126ffa84be55e 334 SUPERFAMILY SSF53822 62 293 1.13E-15 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS08310 5680c38fb9f9b59e36f8b1851e95c120 340 SUPERFAMILY SSF51726 35 326 2.49E-53 T 29-03-2018 CWR56_RS08310 5680c38fb9f9b59e36f8b1851e95c120 340 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 35 324 2.4E-47 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CWR56_RS08310 5680c38fb9f9b59e36f8b1851e95c120 340 Gene3D G3DSA:3.20.20.210 28 337 5.0E-51 T 29-03-2018 CWR56_RS14805 13472c43da9c418c3036ca7e8acbd708 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 320 3.3E-97 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CWR56_RS14805 13472c43da9c418c3036ca7e8acbd708 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 3 326 2.1E-142 T 29-03-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 CWR56_RS14805 13472c43da9c418c3036ca7e8acbd708 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 311 27.268 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CWR56_RS14805 13472c43da9c418c3036ca7e8acbd708 326 Pfam PF01867 CRISPR associated protein Cas1 5 280 3.1E-90 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CWR56_RS09900 c41c193bdd47f3aa5e5cba983578c1db 125 Gene3D G3DSA:1.10.4040.10 72 120 1.1E-7 T 29-03-2018 CWR56_RS09900 c41c193bdd47f3aa5e5cba983578c1db 125 PIRSF PIRSF019455 1 125 5.5E-33 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS09900 c41c193bdd47f3aa5e5cba983578c1db 125 Gene3D G3DSA:1.10.10.10 8 71 4.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09900 c41c193bdd47f3aa5e5cba983578c1db 125 SUPERFAMILY SSF46785 4 123 3.63E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09900 c41c193bdd47f3aa5e5cba983578c1db 125 Pfam PF03965 Penicillinase repressor 8 118 3.2E-23 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS03665 ddd47cb04c56c19f88fc00120b16e784 267 Gene3D G3DSA:3.30.700.10 6 261 4.4E-17 T 29-03-2018 CWR56_RS03665 ddd47cb04c56c19f88fc00120b16e784 267 SUPERFAMILY SSF54523 6 96 3.37E-14 T 29-03-2018 CWR56_RS03665 ddd47cb04c56c19f88fc00120b16e784 267 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS03665 ddd47cb04c56c19f88fc00120b16e784 267 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 2.4E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS03665 ddd47cb04c56c19f88fc00120b16e784 267 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 3.1E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 421 41.501 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 ProSitePatterns PS00482 Dihydroorotase signature 1. 58 66 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 Gene3D G3DSA:3.20.20.140 70 266 4.9E-53 T 29-03-2018 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 Gene3D G3DSA:3.20.20.140 267 405 2.1E-45 T 29-03-2018 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 Pfam PF01979 Amidohydrolase family 51 418 3.8E-34 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 420 1.0E-123 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 Gene3D G3DSA:2.30.40.10 1 69 2.8E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 SUPERFAMILY SSF51556 55 364 1.58E-103 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 SUPERFAMILY SSF51338 2 54 4.32E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07225 be71bfa2dc67ef107f516de2168827bf 421 SUPERFAMILY SSF51338 366 420 4.32E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17330 eb7b735813bfadcec8e89417bcf9227d 145 PIRSF PIRSF006019 1 145 2.1E-56 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR56_RS17330 eb7b735813bfadcec8e89417bcf9227d 145 Gene3D G3DSA:3.40.140.10 2 145 1.5E-43 T 29-03-2018 CWR56_RS17330 eb7b735813bfadcec8e89417bcf9227d 145 SUPERFAMILY SSF53927 6 144 6.98E-41 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS17330 eb7b735813bfadcec8e89417bcf9227d 145 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 122 3.6E-29 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR56_RS13005 22eae6b68318a0a988b60ef4bf7cc61f 218 Gene3D G3DSA:3.40.109.10 1 218 1.4E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS13005 22eae6b68318a0a988b60ef4bf7cc61f 218 Pfam PF00881 Nitroreductase family 7 196 8.2E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS13005 22eae6b68318a0a988b60ef4bf7cc61f 218 SUPERFAMILY SSF55469 1 63 3.01E-39 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS13005 22eae6b68318a0a988b60ef4bf7cc61f 218 SUPERFAMILY SSF55469 91 218 3.01E-39 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS14840 45fa58bdaba315102c124b76be58c96e 305 Pfam PF08279 HTH domain 3 51 8.6E-7 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS14840 45fa58bdaba315102c124b76be58c96e 305 Gene3D G3DSA:1.10.10.10 1 56 5.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14840 45fa58bdaba315102c124b76be58c96e 305 Pfam PF13280 WYL domain 132 301 8.9E-37 T 29-03-2018 IPR026881 WYL domain CWR56_RS15490 1afcaf2837c525cbe784c7ee1805346f 550 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 422 533 4.0E-13 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15490 1afcaf2837c525cbe784c7ee1805346f 550 Pfam PF00367 phosphotransferase system, EIIB 475 501 7.1E-12 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15490 1afcaf2837c525cbe784c7ee1805346f 550 Gene3D G3DSA:3.30.1360.60 470 547 4.9E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15490 1afcaf2837c525cbe784c7ee1805346f 550 Pfam PF02378 Phosphotransferase system, EIIC 10 361 9.2E-56 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15490 1afcaf2837c525cbe784c7ee1805346f 550 SUPERFAMILY SSF55604 472 548 6.02E-16 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS14570 99f4a1fa1b7efa0a765ec5e73fbd065c 460 Pfam PF01523 Putative modulator of DNA gyrase 21 314 1.0E-62 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CWR56_RS14570 99f4a1fa1b7efa0a765ec5e73fbd065c 460 PIRSF PIRSF004919 1 460 2.0E-125 T 29-03-2018 IPR025502 TldD CWR56_RS14570 99f4a1fa1b7efa0a765ec5e73fbd065c 460 Gene3D G3DSA:3.30.2290.10 2 222 1.0E-39 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CWR56_RS14570 99f4a1fa1b7efa0a765ec5e73fbd065c 460 SUPERFAMILY SSF111283 2 460 1.22E-119 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CWR56_RS03140 7aa51501bd6865769cf111d2f0fb90c0 43 Gene3D G3DSA:3.40.80.10 3 43 2.7E-4 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR56_RS03140 7aa51501bd6865769cf111d2f0fb90c0 43 SUPERFAMILY SSF55846 8 40 1.2E-5 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR56_RS01260 cf53f2041728d34a652312b3845748d9 105 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 105 15.406 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CWR56_RS01260 cf53f2041728d34a652312b3845748d9 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 69 85 2.4E-8 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CWR56_RS01260 cf53f2041728d34a652312b3845748d9 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 90 103 2.4E-8 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CWR56_RS01260 cf53f2041728d34a652312b3845748d9 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 35 51 2.4E-8 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CWR56_RS01260 cf53f2041728d34a652312b3845748d9 105 Pfam PF02049 Flagellar hook-basal body complex protein FliE 26 105 2.9E-22 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CWR56_RS01260 cf53f2041728d34a652312b3845748d9 105 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 29 105 6.5E-17 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CWR56_RS06230 ed114111ddcc3b5bbd8734b9f460bc34 250 SUPERFAMILY SSF56219 1 249 3.27E-85 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWR56_RS06230 ed114111ddcc3b5bbd8734b9f460bc34 250 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 1.1E-100 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CWR56_RS06230 ed114111ddcc3b5bbd8734b9f460bc34 250 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 4.3E-98 T 29-03-2018 CWR56_RS06230 ed114111ddcc3b5bbd8734b9f460bc34 250 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CWR56_RS06230 ed114111ddcc3b5bbd8734b9f460bc34 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 6.6E-23 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWR56_RS06230 ed114111ddcc3b5bbd8734b9f460bc34 250 Gene3D G3DSA:3.60.10.10 1 250 5.7E-59 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 SUPERFAMILY SSF52540 5 252 1.98E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 3.0E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 Pfam PF00005 ABC transporter 26 182 5.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 SMART SM00382 34 232 4.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 319 1.6E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS13510 3c060631793e26160c5acd05e5cd35b8 325 Gene3D G3DSA:3.40.50.300 2 325 8.1E-78 T 29-03-2018 CWR56_RS01070 36576a20a5d59da51fe5eaa918db1e01 387 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 242 325 1.7E-16 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS01070 36576a20a5d59da51fe5eaa918db1e01 387 Pfam PF01385 Probable transposase 164 274 6.4E-9 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CWR56_RS01070 36576a20a5d59da51fe5eaa918db1e01 387 Pfam PF07282 Putative transposase DNA-binding domain 298 363 2.7E-24 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 6.6E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 Gene3D G3DSA:1.10.10.10 122 230 5.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 SUPERFAMILY SSF46894 129 227 2.58E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 Gene3D G3DSA:3.40.50.2300 1 121 1.4E-28 T 29-03-2018 CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 Pfam PF00072 Response regulator receiver domain 5 113 4.4E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 SMART SM00862 151 226 3.1E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 SMART SM00448 3 113 2.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS14865 79f03b4c2bc4f1fa3f33e13631faf177 230 SUPERFAMILY SSF52172 2 126 3.27E-34 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS13205 8b6166e679a91bede877879433830390 358 Gene3D G3DSA:3.90.230.10 121 358 8.9E-77 T 29-03-2018 CWR56_RS13205 8b6166e679a91bede877879433830390 358 Gene3D G3DSA:3.40.350.10 3 120 4.4E-14 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR56_RS13205 8b6166e679a91bede877879433830390 358 SUPERFAMILY SSF55920 130 357 2.09E-73 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS13205 8b6166e679a91bede877879433830390 358 SUPERFAMILY SSF53092 4 130 2.27E-13 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR56_RS13205 8b6166e679a91bede877879433830390 358 Pfam PF00557 Metallopeptidase family M24 138 341 2.2E-63 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS13205 8b6166e679a91bede877879433830390 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 131 1.6E-16 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR56_RS13205 8b6166e679a91bede877879433830390 358 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 287 299 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 SUPERFAMILY SSF50249 6 115 5.52E-34 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 8 589 1.2E-245 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 SUPERFAMILY SSF55681 113 300 2.19E-105 T 29-03-2018 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 SUPERFAMILY SSF55681 429 589 2.19E-105 T 29-03-2018 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 126 564 1.7E-108 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 SUPERFAMILY SSF55261 297 423 1.13E-41 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 Pfam PF02938 GAD domain 316 410 6.2E-29 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 Pfam PF01336 OB-fold nucleic acid binding domain 25 108 9.7E-14 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 Gene3D G3DSA:3.30.930.10 139 592 1.1E-106 T 29-03-2018 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 480 496 4.4E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 215 228 4.4E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 210 4.4E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 524 538 4.4E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 Gene3D G3DSA:2.40.50.140 2 114 4.4E-30 T 29-03-2018 CWR56_RS13890 e22f7cf2e129f1bcb6fee5f372ddb587 595 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 8 590 34.157 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CWR56_RS12525 e3769e6debead60bf6295d580495225b 278 SMART SM00849 34 228 8.3E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12525 e3769e6debead60bf6295d580495225b 278 Pfam PF00753 Metallo-beta-lactamase superfamily 32 106 1.3E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12525 e3769e6debead60bf6295d580495225b 278 SUPERFAMILY SSF56281 25 269 1.7E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS12525 e3769e6debead60bf6295d580495225b 278 Gene3D G3DSA:3.60.15.10 20 252 4.6E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS08620 c16f0980c5a0d422f215f1c8b507130e 329 SUPERFAMILY SSF53098 5 190 2.34E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS08620 c16f0980c5a0d422f215f1c8b507130e 329 Pfam PF00929 Exonuclease 10 185 4.7E-12 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS08620 c16f0980c5a0d422f215f1c8b507130e 329 SMART SM00479 8 196 6.6E-5 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS08620 c16f0980c5a0d422f215f1c8b507130e 329 Gene3D G3DSA:3.30.420.10 7 191 1.1E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS09025 7551d39b2bb123ee2a61fa673c396847 178 Pfam PF01252 Signal peptidase (SPase) II 17 155 1.1E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS05450 5a88d6839f223712b95401051a6df8a7 128 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 127 2.2E-28 T 29-03-2018 IPR014211 Stage III sporulation protein AD CWR56_RS05450 5a88d6839f223712b95401051a6df8a7 128 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 125 5.1E-17 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CWR56_RS05450 5a88d6839f223712b95401051a6df8a7 128 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 4.1E-11 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CWR56_RS08375 9769f9ac0ff2623a3a05688b290c04ff 74 SUPERFAMILY SSF50037 5 72 5.49E-19 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR56_RS08375 9769f9ac0ff2623a3a05688b290c04ff 74 Pfam PF04023 FeoA domain 1 71 5.6E-15 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS08375 9769f9ac0ff2623a3a05688b290c04ff 74 Gene3D G3DSA:2.30.30.90 4 74 2.4E-17 T 29-03-2018 CWR56_RS08375 9769f9ac0ff2623a3a05688b290c04ff 74 SMART SM00899 1 73 7.1E-20 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS06440 3d682b876bd1e65ff0db18c86c20f290 132 SMART SM00530 7 60 1.2E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06440 3d682b876bd1e65ff0db18c86c20f290 132 Gene3D G3DSA:1.10.260.40 3 122 1.7E-17 T 29-03-2018 CWR56_RS06440 3d682b876bd1e65ff0db18c86c20f290 132 Pfam PF01381 Helix-turn-helix 8 60 1.6E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06440 3d682b876bd1e65ff0db18c86c20f290 132 SUPERFAMILY SSF47413 3 66 3.38E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS05860 0e1ff109d3b55fc08966c39b1d72e002 354 Gene3D G3DSA:3.40.1710.10 42 183 2.6E-4 T 29-03-2018 CWR56_RS05860 0e1ff109d3b55fc08966c39b1d72e002 354 Pfam PF12698 ABC-2 family transporter protein 19 344 1.2E-27 T 29-03-2018 CWR56_RS05990 ae3d9584f30d85eb6218d7666bd2c576 140 Pfam PF09391 Protein of unknown function (DUF2000) 7 140 2.1E-49 T 29-03-2018 IPR018988 Protein of unknown function DUF2000 CWR56_RS05990 ae3d9584f30d85eb6218d7666bd2c576 140 SUPERFAMILY SSF102462 5 140 3.09E-45 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CWR56_RS05990 ae3d9584f30d85eb6218d7666bd2c576 140 Gene3D G3DSA:3.40.1490.10 6 138 1.1E-47 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CWR56_RS05990 ae3d9584f30d85eb6218d7666bd2c576 140 PIRSF PIRSF033736 1 140 7.5E-51 T 29-03-2018 IPR017021 Uncharacterised conserved protein UCP033763 CWR56_RS06035 a37b8be12dfbd9a0e5a19efbe9f22e8d 222 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 6 196 2.4E-14 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CWR56_RS08770 baa0f88c260541b391b9b0d6c96df53c 279 Gene3D G3DSA:3.40.50.1970 135 249 2.7E-4 T 29-03-2018 CWR56_RS08770 baa0f88c260541b391b9b0d6c96df53c 279 Pfam PF02401 LytB protein 3 276 2.1E-95 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CWR56_RS08770 baa0f88c260541b391b9b0d6c96df53c 279 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 279 31.775 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CWR56_RS08770 baa0f88c260541b391b9b0d6c96df53c 279 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 278 7.1E-94 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CWR56_RS06940 faec280588d27e7beec8230332e14daa 181 SUPERFAMILY SSF57802 1 44 2.36E-11 T 29-03-2018 CWR56_RS06940 faec280588d27e7beec8230332e14daa 181 Gene3D G3DSA:1.20.1260.10 25 123 1.9E-23 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS06940 faec280588d27e7beec8230332e14daa 181 SUPERFAMILY SSF47240 54 179 2.26E-32 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS06940 faec280588d27e7beec8230332e14daa 181 Pfam PF02915 Rubrerythrin 61 174 1.5E-12 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CWR56_RS06940 faec280588d27e7beec8230332e14daa 181 Gene3D G3DSA:1.20.1260.10 124 181 1.3E-7 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS06940 faec280588d27e7beec8230332e14daa 181 Gene3D G3DSA:2.20.28.10 1 24 1.1E-7 T 29-03-2018 CWR56_RS08730 8ac3b7195ce2ef4484fdc98c43c2d334 125 Gene3D G3DSA:1.10.10.10 7 71 2.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08730 8ac3b7195ce2ef4484fdc98c43c2d334 125 PIRSF PIRSF019455 1 125 5.1E-33 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS08730 8ac3b7195ce2ef4484fdc98c43c2d334 125 SUPERFAMILY SSF46785 5 124 1.24E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08730 8ac3b7195ce2ef4484fdc98c43c2d334 125 Pfam PF03965 Penicillinase repressor 8 113 2.9E-24 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS08730 8ac3b7195ce2ef4484fdc98c43c2d334 125 Gene3D G3DSA:1.10.4040.10 72 120 3.2E-7 T 29-03-2018 CWR56_RS06955 e72f13be57ee3f24203b1f746c409422 70 Gene3D G3DSA:2.30.30.90 1 70 1.2E-16 T 29-03-2018 CWR56_RS06955 e72f13be57ee3f24203b1f746c409422 70 Pfam PF04023 FeoA domain 2 70 1.1E-13 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS06955 e72f13be57ee3f24203b1f746c409422 70 SUPERFAMILY SSF50037 8 70 1.17E-10 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR56_RS06955 e72f13be57ee3f24203b1f746c409422 70 SMART SM00899 2 70 1.1E-7 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS14045 905b37cc53c7c66a768e954b8baafb1d 637 SUPERFAMILY SSF53335 118 339 1.11E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS14045 905b37cc53c7c66a768e954b8baafb1d 637 Gene3D G3DSA:3.40.50.720 152 278 1.7E-29 T 29-03-2018 CWR56_RS14045 905b37cc53c7c66a768e954b8baafb1d 637 SUPERFAMILY SSF51735 294 559 2.09E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS14045 905b37cc53c7c66a768e954b8baafb1d 637 Pfam PF13727 CoA-binding domain 133 252 1.0E-12 T 29-03-2018 CWR56_RS14045 905b37cc53c7c66a768e954b8baafb1d 637 Gene3D G3DSA:3.40.50.720 291 618 2.1E-68 T 29-03-2018 CWR56_RS14045 905b37cc53c7c66a768e954b8baafb1d 637 Pfam PF02719 Polysaccharide biosynthesis protein 297 579 2.9E-125 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CWR56_RS10420 2499ae515ac05d35b06ef5e328ec2c74 167 SUPERFAMILY SSF55729 17 162 6.08E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS10420 2499ae515ac05d35b06ef5e328ec2c74 167 Pfam PF00583 Acetyltransferase (GNAT) family 67 150 8.0E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS10420 2499ae515ac05d35b06ef5e328ec2c74 167 Gene3D G3DSA:3.40.630.30 15 166 2.0E-16 T 29-03-2018 CWR56_RS09055 f979df0170ad14d56e54924d2ca21258 116 PIRSF PIRSF012296 1 116 1.7E-58 T 29-03-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 CWR56_RS09055 f979df0170ad14d56e54924d2ca21258 116 Pfam PF00936 BMC domain 45 107 2.5E-15 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09055 f979df0170ad14d56e54924d2ca21258 116 SUPERFAMILY SSF143414 44 107 1.31E-15 T 29-03-2018 CWR56_RS09055 f979df0170ad14d56e54924d2ca21258 116 SMART SM00877 44 116 2.6E-22 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS10135 737c5f31b62b28be861d32d3512c62cb 224 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 214 4.4E-76 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CWR56_RS10135 737c5f31b62b28be861d32d3512c62cb 224 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS10135 737c5f31b62b28be861d32d3512c62cb 224 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 213 2.5E-55 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS10135 737c5f31b62b28be861d32d3512c62cb 224 ProSitePatterns PS00958 Transaldolase active site. 82 99 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS10135 737c5f31b62b28be861d32d3512c62cb 224 SUPERFAMILY SSF51569 1 215 1.26E-70 T 29-03-2018 CWR56_RS10135 737c5f31b62b28be861d32d3512c62cb 224 Gene3D G3DSA:3.20.20.70 1 222 3.1E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 Gene3D G3DSA:3.40.190.10 89 181 7.9E-15 T 29-03-2018 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 SUPERFAMILY SSF53850 91 292 1.86E-29 T 29-03-2018 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.6E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 Pfam PF03466 LysR substrate binding domain 89 292 3.7E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 Gene3D G3DSA:3.40.190.10 182 270 1.3E-16 T 29-03-2018 CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 Gene3D G3DSA:1.10.10.10 1 83 9.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18180 aba2856327d339f93f7b77038ad34cbb 293 SUPERFAMILY SSF46785 2 87 2.73E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13315 4b1e3363df21dc29a5ba44bc97103c9a 204 Pfam PF02660 Glycerol-3-phosphate acyltransferase 12 191 6.9E-53 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR56_RS13315 4b1e3363df21dc29a5ba44bc97103c9a 204 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 7 202 5.3E-54 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR56_RS13315 4b1e3363df21dc29a5ba44bc97103c9a 204 SMART SM01207 11 192 2.3E-78 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR56_RS13315 4b1e3363df21dc29a5ba44bc97103c9a 204 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 200 20.558 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR56_RS02140 fa7780c246257e859ff173da1e0f475d 254 Pfam PF01380 SIS domain 111 239 8.3E-17 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS02140 fa7780c246257e859ff173da1e0f475d 254 Gene3D G3DSA:1.10.10.10 1 104 4.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02140 fa7780c246257e859ff173da1e0f475d 254 Gene3D G3DSA:3.40.50.10490 105 222 9.4E-14 T 29-03-2018 CWR56_RS02140 fa7780c246257e859ff173da1e0f475d 254 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 69 1.3E-14 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS02140 fa7780c246257e859ff173da1e0f475d 254 SUPERFAMILY SSF46689 1 72 3.23E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02140 fa7780c246257e859ff173da1e0f475d 254 SUPERFAMILY SSF53697 81 243 1.62E-20 T 29-03-2018 CWR56_RS01755 30ab04ef1854f733356e87e47c118175 223 Pfam PF00005 ABC transporter 23 169 2.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01755 30ab04ef1854f733356e87e47c118175 223 SUPERFAMILY SSF52540 3 219 4.66E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01755 30ab04ef1854f733356e87e47c118175 223 Gene3D G3DSA:3.40.50.300 1 221 5.1E-66 T 29-03-2018 CWR56_RS01755 30ab04ef1854f733356e87e47c118175 223 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS01755 30ab04ef1854f733356e87e47c118175 223 SMART SM00382 32 218 2.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14080 be8b242aac700fa8a64d944190dc5fd6 279 Pfam PF00535 Glycosyl transferase family 2 4 123 2.6E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS14080 be8b242aac700fa8a64d944190dc5fd6 279 SUPERFAMILY SSF53448 1 240 1.13E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14080 be8b242aac700fa8a64d944190dc5fd6 279 Gene3D G3DSA:3.90.550.10 1 218 2.2E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01145 323b3695c7241821430acdb2c13ed715 142 SUPERFAMILY SSF158397 27 141 2.48E-31 T 29-03-2018 CWR56_RS01145 323b3695c7241821430acdb2c13ed715 142 Gene3D G3DSA:1.20.120.490 27 141 1.1E-30 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain CWR56_RS01145 323b3695c7241821430acdb2c13ed715 142 Pfam PF03885 Protein of unknown function (DUF327) 19 141 1.7E-33 T 29-03-2018 IPR005585 Protein of unknown function DUF327 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 Gene3D G3DSA:3.40.640.10 123 367 8.4E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 Gene3D G3DSA:3.90.1150.10 368 469 8.9E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 Pfam PF00155 Aminotransferase class I and II 137 431 3.0E-15 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 SUPERFAMILY SSF46785 6 78 5.55E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 Gene3D G3DSA:1.10.10.10 1 78 8.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 SMART SM00345 17 76 1.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 SUPERFAMILY SSF53383 99 465 1.24E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 9.4E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.0E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS16790 eb6e00263dbdbcef5e97f0eb751a8ca4 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.0E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 Pfam PF03123 CAT RNA binding domain 1 55 7.9E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 SUPERFAMILY SSF50151 1 53 1.26E-15 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 Gene3D G3DSA:1.10.1790.10 54 165 1.5E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 Gene3D G3DSA:2.30.24.10 1 53 4.8E-19 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 Pfam PF00874 PRD domain 86 160 3.0E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 Pfam PF00874 PRD domain 179 268 3.0E-9 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 SUPERFAMILY SSF63520 167 268 3.27E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 SMART SM01061 1 59 1.2E-25 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 Gene3D G3DSA:1.10.1790.10 166 270 3.4E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS12685 915d06e42fc10f2771e04ca5d87f687f 271 SUPERFAMILY SSF63520 57 165 1.28E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS08800 1a0018c88ee9f92141d13eb33e1f5af8 421 PIRSF PIRSF001434 2 421 8.5E-118 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR56_RS08800 1a0018c88ee9f92141d13eb33e1f5af8 421 Gene3D G3DSA:3.90.1150.10 288 421 1.4E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS08800 1a0018c88ee9f92141d13eb33e1f5af8 421 Gene3D G3DSA:3.40.640.10 2 286 3.6E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS08800 1a0018c88ee9f92141d13eb33e1f5af8 421 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 419 1.2E-126 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR56_RS08800 1a0018c88ee9f92141d13eb33e1f5af8 421 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 4 419 2.4E-176 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CWR56_RS08800 1a0018c88ee9f92141d13eb33e1f5af8 421 SUPERFAMILY SSF53383 4 420 7.07E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS16690 46e7569ad6a656d85e6a4735b0c8d6f8 352 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 19 326 8.6E-33 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR56_RS16690 46e7569ad6a656d85e6a4735b0c8d6f8 352 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 24 340 5.2E-15 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 SUPERFAMILY SSF82649 239 324 8.37E-22 T 29-03-2018 CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 Pfam PF03099 Biotin/lipoate A/B protein ligase family 44 147 3.1E-9 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 3 312 1.0E-102 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 Gene3D G3DSA:3.30.390.50 243 326 1.4E-19 T 29-03-2018 CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 SUPERFAMILY SSF55681 1 238 1.14E-77 T 29-03-2018 CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 Gene3D G3DSA:3.30.930.10 1 242 2.7E-73 T 29-03-2018 CWR56_RS07880 18e3ff0792dabad296ce8bc347fbf685 328 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 240 322 3.1E-23 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CWR56_RS13240 adf182c7611ccf8e608e5e4b48f56b4b 261 SMART SM00363 185 242 0.006 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS13240 adf182c7611ccf8e608e5e4b48f56b4b 261 SUPERFAMILY SSF55174 182 259 4.71E-25 T 29-03-2018 CWR56_RS13240 adf182c7611ccf8e608e5e4b48f56b4b 261 SUPERFAMILY SSF55174 51 130 4.71E-25 T 29-03-2018 CWR56_RS13240 adf182c7611ccf8e608e5e4b48f56b4b 261 Gene3D G3DSA:3.10.290.10 185 260 5.5E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS06130 33b6ee3cb5c7c41bf8607ea131f4e869 247 SUPERFAMILY SSF88713 47 246 3.71E-49 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS06130 33b6ee3cb5c7c41bf8607ea131f4e869 247 Gene3D G3DSA:3.20.20.370 46 247 1.1E-47 T 29-03-2018 CWR56_RS06130 33b6ee3cb5c7c41bf8607ea131f4e869 247 Pfam PF01522 Polysaccharide deacetylase 62 178 1.8E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 Gene3D G3DSA:1.10.8.60 512 583 4.0E-14 T 29-03-2018 CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 SUPERFAMILY SSF52540 338 577 2.6E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 363 376 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 Gene3D G3DSA:1.10.10.10 584 674 0.0011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 Gene3D G3DSA:3.40.50.300 332 511 1.4E-23 T 29-03-2018 CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 426 441 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 Pfam PF00158 Sigma-54 interaction domain 339 506 9.1E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS13665 00dde8f4f32c6209a1f622ebd5a1e7b1 674 SMART SM00382 359 502 2.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS11730 ed8fe108d28230876c6ef08511fb906f 250 SUPERFAMILY SSF52540 3 233 1.2E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11730 ed8fe108d28230876c6ef08511fb906f 250 SMART SM00382 31 211 2.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS11730 ed8fe108d28230876c6ef08511fb906f 250 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS11730 ed8fe108d28230876c6ef08511fb906f 250 Gene3D G3DSA:3.40.50.300 1 241 2.4E-59 T 29-03-2018 CWR56_RS11730 ed8fe108d28230876c6ef08511fb906f 250 Pfam PF00005 ABC transporter 22 161 5.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 SUPERFAMILY SSF111369 47 139 1.96E-9 T 29-03-2018 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 Pfam PF13533 Biotin-lipoyl like 59 105 1.1E-8 T 29-03-2018 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 Gene3D G3DSA:2.40.50.100 57 117 2.0E-11 T 29-03-2018 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 175 321 3.8E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 195 400 5.2E-41 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 SUPERFAMILY SSF111369 166 325 5.1E-12 T 29-03-2018 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 Gene3D G3DSA:1.10.287.470 118 188 6.1E-8 T 29-03-2018 CWR56_RS12145 ba6d8734c36c57f50dd8e34c556a0673 407 Gene3D G3DSA:1.20.1600.10 193 330 1.4E-4 T 29-03-2018 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 Gene3D G3DSA:3.20.20.140 62 276 6.7E-60 T 29-03-2018 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 Gene3D G3DSA:3.20.20.140 277 423 8.6E-45 T 29-03-2018 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 SUPERFAMILY SSF51556 53 382 3.11E-114 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 Gene3D G3DSA:2.30.40.10 1 61 1.4E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 SUPERFAMILY SSF51338 1 64 5.18E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 3 454 7.2E-184 T 29-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 Pfam PF01979 Amidohydrolase family 49 436 7.3E-30 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS15955 9f1dbc6276a2c4978a013877cfb767ff 463 SUPERFAMILY SSF51338 352 455 2.59E-32 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS03585 a434c88d4af7083d93ec8348123d9bf4 365 SUPERFAMILY SSF53383 1 360 3.35E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS03585 a434c88d4af7083d93ec8348123d9bf4 365 Pfam PF00266 Aminotransferase class-V 5 310 1.5E-30 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS03585 a434c88d4af7083d93ec8348123d9bf4 365 Gene3D G3DSA:3.90.1150.10 272 364 5.6E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS03585 a434c88d4af7083d93ec8348123d9bf4 365 PIRSF PIRSF000524 1 364 2.5E-70 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CWR56_RS03585 a434c88d4af7083d93ec8348123d9bf4 365 Gene3D G3DSA:3.40.640.10 12 271 4.8E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 Gene3D G3DSA:1.10.286.10 7 55 2.7E-25 T 29-03-2018 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 66 82 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 115 125 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 Gene3D G3DSA:3.30.1130.10 57 190 1.7E-56 T 29-03-2018 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 Pfam PF01227 GTP cyclohydrolase I 9 187 2.8E-77 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 1.4E-73 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 188 42.164 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR56_RS06815 0a1e74d6efd4b6efec944ae32de2f4f5 190 SUPERFAMILY SSF55620 2 188 6.97E-78 T 29-03-2018 CWR56_RS08160 bd19794b393e36e39bfed7314a24be77 367 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 3 366 1.4E-142 T 29-03-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 CWR56_RS08160 bd19794b393e36e39bfed7314a24be77 367 Gene3D G3DSA:3.20.20.70 22 367 3.4E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS08160 bd19794b393e36e39bfed7314a24be77 367 SMART SM00876 256 359 2.5E-25 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS08160 bd19794b393e36e39bfed7314a24be77 367 Pfam PF04055 Radical SAM superfamily 80 225 7.9E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS08160 bd19794b393e36e39bfed7314a24be77 367 SUPERFAMILY SSF102114 42 356 4.32E-42 T 29-03-2018 CWR56_RS08160 bd19794b393e36e39bfed7314a24be77 367 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 256 358 9.3E-22 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Gene3D G3DSA:2.60.120.40 537 677 1.9E-14 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Pfam PF01391 Collagen triple helix repeat (20 copies) 476 534 5.4E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Gene3D G3DSA:2.160.20.50 426 482 5.4E-13 T 29-03-2018 CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Gene3D G3DSA:2.160.20.50 293 370 1.2E-12 T 29-03-2018 CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Gene3D G3DSA:2.160.20.50 483 536 3.5E-15 T 29-03-2018 CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Gene3D G3DSA:2.160.20.50 180 259 3.4E-17 T 29-03-2018 CWR56_RS01735 61fcda7d81947bb1e5b01627962f70cc 681 Gene3D G3DSA:2.160.20.50 371 425 1.5E-13 T 29-03-2018 CWR56_RS10370 a221d883f510b6b4e5efae71a297d44c 346 PIRSF PIRSF001123 6 345 3.6E-37 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS10370 a221d883f510b6b4e5efae71a297d44c 346 SUPERFAMILY SSF101821 74 187 3.51E-25 T 29-03-2018 CWR56_RS10370 a221d883f510b6b4e5efae71a297d44c 346 Gene3D G3DSA:3.40.630.10 1 345 4.3E-40 T 29-03-2018 CWR56_RS10370 a221d883f510b6b4e5efae71a297d44c 346 SUPERFAMILY SSF53187 182 344 2.27E-50 T 29-03-2018 CWR56_RS10370 a221d883f510b6b4e5efae71a297d44c 346 SUPERFAMILY SSF53187 7 86 2.27E-50 T 29-03-2018 CWR56_RS10370 a221d883f510b6b4e5efae71a297d44c 346 Pfam PF05343 M42 glutamyl aminopeptidase 49 338 1.2E-74 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS08670 81e9e156afb7f90d92d2585978abaac5 188 Pfam PF02342 TerD domain 1 187 3.3E-70 T 29-03-2018 IPR003325 TerD domain GO:0006950 CWR56_RS08670 81e9e156afb7f90d92d2585978abaac5 188 Gene3D G3DSA:2.60.60.30 20 186 3.2E-51 T 29-03-2018 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 Hamap MF_00422 Protein translocase subunit SecE [secE]. 10 70 11.462 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 Gene3D G3DSA:1.20.5.1030 17 68 3.5E-19 T 29-03-2018 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 PRINTS PR01650 Bacterial translocase SecE signature 14 34 5.6E-7 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 PRINTS PR01650 Bacterial translocase SecE signature 58 73 5.6E-7 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 PRINTS PR01650 Bacterial translocase SecE signature 38 58 5.6E-7 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 18 73 4.4E-18 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 19 70 1.1E-18 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00015 22b38e287bb7e881aefac632924afce2 73 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 20 48 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS16460 265fe53fc0c4ad697e97b0017dfe04d3 72 Pfam PF04023 FeoA domain 1 70 2.2E-13 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS16460 265fe53fc0c4ad697e97b0017dfe04d3 72 SUPERFAMILY SSF50037 5 71 3.97E-17 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR56_RS16460 265fe53fc0c4ad697e97b0017dfe04d3 72 Gene3D G3DSA:2.30.30.90 4 72 2.8E-16 T 29-03-2018 CWR56_RS16460 265fe53fc0c4ad697e97b0017dfe04d3 72 SMART SM00899 1 71 1.8E-15 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 Gene3D G3DSA:3.40.50.2300 1 121 8.8E-33 T 29-03-2018 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 Pfam PF00072 Response regulator receiver domain 3 111 1.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 9.1E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 SUPERFAMILY SSF46894 124 221 3.97E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 SMART SM00448 1 111 8.5E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 SUPERFAMILY SSF52172 1 120 5.83E-36 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 SMART SM00862 145 220 5.4E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS08070 39e520a1315a52998487bd9b5fd733e3 223 Gene3D G3DSA:1.10.10.10 122 223 1.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04040 11437886d9ed6a8811c3ed0239400cdc 178 SUPERFAMILY SSF57802 135 177 3.08E-12 T 29-03-2018 CWR56_RS04040 11437886d9ed6a8811c3ed0239400cdc 178 Gene3D G3DSA:1.20.1260.10 2 66 9.5E-21 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS04040 11437886d9ed6a8811c3ed0239400cdc 178 SUPERFAMILY SSF47240 3 134 1.72E-40 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS04040 11437886d9ed6a8811c3ed0239400cdc 178 Gene3D G3DSA:1.20.1260.10 67 139 5.7E-12 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS04040 11437886d9ed6a8811c3ed0239400cdc 178 Pfam PF02915 Rubrerythrin 10 126 1.4E-23 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CWR56_RS04040 11437886d9ed6a8811c3ed0239400cdc 178 Gene3D G3DSA:2.20.28.10 140 173 4.3E-10 T 29-03-2018 CWR56_RS17835 04999914fdc1128debc653f370b0f98d 165 Gene3D G3DSA:3.10.450.50 4 165 1.5E-18 T 29-03-2018 CWR56_RS17835 04999914fdc1128debc653f370b0f98d 165 Pfam PF02810 SEC-C motif 147 165 1.4E-9 T 29-03-2018 IPR004027 SEC-C motif CWR56_RS17835 04999914fdc1128debc653f370b0f98d 165 SUPERFAMILY SSF103642 144 164 1.64E-7 T 29-03-2018 CWR56_RS07395 55a9b79c024f004ea551144bd8b929b1 289 Pfam PF11738 Protein of unknown function (DUF3298) 200 284 8.8E-22 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS07395 55a9b79c024f004ea551144bd8b929b1 289 Gene3D G3DSA:3.90.640.20 196 289 6.6E-26 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS07395 55a9b79c024f004ea551144bd8b929b1 289 Pfam PF13739 Domain of unknown function (DUF4163) 93 171 1.5E-8 T 29-03-2018 IPR025303 Deacetylase PdaC CWR56_RS07395 55a9b79c024f004ea551144bd8b929b1 289 Gene3D G3DSA:3.30.565.40 80 195 1.1E-12 T 29-03-2018 CWR56_RS08490 0b99a3d11390d284276cd961811a2596 202 Pfam PF00293 NUDIX domain 59 176 1.0E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS08490 0b99a3d11390d284276cd961811a2596 202 Gene3D G3DSA:3.90.79.10 1 198 4.9E-31 T 29-03-2018 CWR56_RS08490 0b99a3d11390d284276cd961811a2596 202 SUPERFAMILY SSF55811 53 194 9.21E-30 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS08490 0b99a3d11390d284276cd961811a2596 202 PRINTS PR00502 NUDIX hydrolase family signature 102 117 6.0E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS08490 0b99a3d11390d284276cd961811a2596 202 PRINTS PR00502 NUDIX hydrolase family signature 88 102 6.0E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 Gene3D G3DSA:1.10.10.60 7 40 3.3E-10 T 29-03-2018 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 Pfam PF08359 YsiA-like protein, C-terminal region 68 168 9.9E-5 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 Gene3D G3DSA:1.10.260.40 41 72 5.9E-7 T 29-03-2018 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 Gene3D G3DSA:1.10.357.10 73 196 2.0E-20 T 29-03-2018 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 SUPERFAMILY SSF46689 6 90 1.98E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS11040 e6dacc62965ca84c1e8ea984740af8b4 203 SUPERFAMILY SSF48498 86 197 1.38E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 Pfam PF06445 GyrI-like small molecule binding domain 199 262 6.2E-6 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 SMART SM00422 6 75 3.7E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 SUPERFAMILY SSF55136 165 268 5.23E-17 T 29-03-2018 CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 Pfam PF13411 MerR HTH family regulatory protein 6 74 2.9E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 Gene3D G3DSA:1.10.1660.10 62 125 1.0E-7 T 29-03-2018 CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 SUPERFAMILY SSF46955 5 111 4.03E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 Gene3D G3DSA:1.10.1660.10 2 61 3.7E-20 T 29-03-2018 CWR56_RS09755 a3e99285d3f5b4e997ae9095c49b4909 269 Gene3D G3DSA:3.20.80.10 126 269 6.8E-15 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 Pfam PF03466 LysR substrate binding domain 90 289 1.5E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 Gene3D G3DSA:3.40.190.10 178 265 2.1E-16 T 29-03-2018 CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 SUPERFAMILY SSF53850 90 293 4.03E-36 T 29-03-2018 CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 SUPERFAMILY SSF46785 1 107 1.04E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 Gene3D G3DSA:1.10.10.10 1 83 2.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 Gene3D G3DSA:3.40.190.10 90 177 1.4E-15 T 29-03-2018 CWR56_RS08660 cdb2eae2c7afe8721b0523af2983b937 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR56_RS16360 6d66ae85bea9dc75f237cfc29004e855 337 SUPERFAMILY SSF52743 4 231 2.62E-32 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS16360 6d66ae85bea9dc75f237cfc29004e855 337 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 7 18 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CWR56_RS16360 6d66ae85bea9dc75f237cfc29004e855 337 PRINTS PR00723 Subtilisin serine protease family (S8) signature 46 59 6.0E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS16360 6d66ae85bea9dc75f237cfc29004e855 337 PRINTS PR00723 Subtilisin serine protease family (S8) signature 2 21 6.0E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS16360 6d66ae85bea9dc75f237cfc29004e855 337 Gene3D G3DSA:3.40.50.200 1 255 3.0E-25 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS16360 6d66ae85bea9dc75f237cfc29004e855 337 Pfam PF00082 Subtilase family 3 165 3.4E-9 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS04250 acf58c6f826a741a44e59e14fc091429 284 SUPERFAMILY SSF52949 107 284 1.4E-48 T 29-03-2018 CWR56_RS04250 acf58c6f826a741a44e59e14fc091429 284 Pfam PF01661 Macro domain 123 247 4.4E-32 T 29-03-2018 IPR002589 Macro domain CWR56_RS04250 acf58c6f826a741a44e59e14fc091429 284 SMART SM00506 106 248 2.8E-21 T 29-03-2018 IPR002589 Macro domain CWR56_RS04250 acf58c6f826a741a44e59e14fc091429 284 Gene3D G3DSA:3.40.220.10 18 284 5.2E-55 T 29-03-2018 CWR56_RS05785 01642a497c804fdbe93c2ea264477647 122 Gene3D G3DSA:1.10.10.10 1 114 7.8E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05785 01642a497c804fdbe93c2ea264477647 122 Hamap MF_00245 UPF0122 protein . 3 107 19.151 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CWR56_RS05785 01642a497c804fdbe93c2ea264477647 122 SUPERFAMILY SSF88659 2 94 1.53E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS05785 01642a497c804fdbe93c2ea264477647 122 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 94 3.8E-28 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CWR56_RS08235 94d80d05c425f2b2f9a658f39e3e2d5a 180 Gene3D G3DSA:3.30.70.1260 97 180 1.1E-16 T 29-03-2018 CWR56_RS08235 94d80d05c425f2b2f9a658f39e3e2d5a 180 SUPERFAMILY SSF160379 1 179 3.4E-51 T 29-03-2018 CWR56_RS08235 94d80d05c425f2b2f9a658f39e3e2d5a 180 Pfam PF08002 Protein of unknown function (DUF1697) 1 139 3.4E-39 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 CWR56_RS08235 94d80d05c425f2b2f9a658f39e3e2d5a 180 PIRSF PIRSF008502 1 180 1.8E-36 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 CWR56_RS08235 94d80d05c425f2b2f9a658f39e3e2d5a 180 Gene3D G3DSA:3.30.70.1280 2 87 1.8E-27 T 29-03-2018 CWR56_RS02855 203f9c24c330e0d5297f15d7dd09f642 190 Pfam PF09347 Domain of unknown function (DUF1989) 4 162 6.7E-41 T 29-03-2018 IPR018959 Domain of unknown function DUF1989 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PIRSF PIRSF004557 1 422 3.8E-123 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 421 29.487 T 29-03-2018 IPR026593 Protein translocase subunit SecY CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 417 1.5E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 390 408 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 168 191 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 358 376 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 303 325 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 142 167 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 PRINTS PR00303 Preprotein translocase SecY subunit signature 260 279 3.3E-92 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 Gene3D G3DSA:1.10.3370.10 1 422 1.9E-154 T 29-03-2018 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 ProSitePatterns PS00756 Protein secY signature 2. 161 178 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 SUPERFAMILY SSF103491 2 411 1.7E-121 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS00185 10fbfec448bf4aef6cc451baf642c204 422 Pfam PF00344 SecY translocase 69 404 3.3E-112 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 421 4.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 Gene3D G3DSA:3.30.565.10 263 423 1.0E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 SMART SM00388 202 268 1.6E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 266 1.0E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 422 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 SUPERFAMILY SSF55874 257 421 4.58E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 Gene3D G3DSA:1.10.287.130 193 262 2.5E-9 T 29-03-2018 CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 SMART SM00387 313 424 4.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS12815 b73dc636d1e149c2924b31d563af4498 424 SUPERFAMILY SSF47384 187 266 2.35E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS08935 47017cefaac7f47e57aa480e7c647c84 173 SUPERFAMILY SSF46785 3 172 2.33E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08935 47017cefaac7f47e57aa480e7c647c84 173 Pfam PF03551 Transcriptional regulator PadR-like family 6 82 8.9E-11 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR56_RS08935 47017cefaac7f47e57aa480e7c647c84 173 Gene3D G3DSA:1.10.10.10 1 94 8.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 Gene3D G3DSA:1.10.10.10 2 66 8.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 Pfam PF01614 Bacterial transcriptional regulator 130 252 7.7E-33 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 Pfam PF09339 IclR helix-turn-helix domain 7 57 2.0E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 SUPERFAMILY SSF46785 5 78 1.67E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 SUPERFAMILY SSF55781 70 254 3.27E-35 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 Gene3D G3DSA:3.30.450.40 76 255 4.2E-34 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS12270 8b96bfe1889ea8ed843f0327265b3202 255 SMART SM00346 5 95 9.7E-27 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CWR56_RS15770 9fdab5adfe0f0eaa49c19ac792375981 602 Gene3D G3DSA:3.40.50.300 7 351 0.001 T 29-03-2018 CWR56_RS15770 9fdab5adfe0f0eaa49c19ac792375981 602 TIGRFAM TIGR03238 dnd_assoc_3: DNA phosphorothioation-dependent restriction protein DptF 27 591 2.8E-81 T 29-03-2018 IPR017647 DNA phosphorothioation-dependent restriction protein DptF CWR56_RS18435 120aacc3adc680dccc0ebc1400811105 45 Pfam PF00468 Ribosomal protein L34 3 45 2.9E-22 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18435 120aacc3adc680dccc0ebc1400811105 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.201 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18435 120aacc3adc680dccc0ebc1400811105 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 44 9.8E-21 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18435 120aacc3adc680dccc0ebc1400811105 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 43 1.0E-9 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18435 120aacc3adc680dccc0ebc1400811105 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS09990 69b563afbca81d290982f002049ef536 468 Gene3D G3DSA:2.30.40.10 1 78 1.4E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09990 69b563afbca81d290982f002049ef536 468 Gene3D G3DSA:3.20.20.140 79 392 1.3E-62 T 29-03-2018 CWR56_RS09990 69b563afbca81d290982f002049ef536 468 SUPERFAMILY SSF51556 62 375 6.41E-94 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS09990 69b563afbca81d290982f002049ef536 468 SUPERFAMILY SSF51338 2 62 2.32E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09990 69b563afbca81d290982f002049ef536 468 SUPERFAMILY SSF51338 374 449 2.32E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS09990 69b563afbca81d290982f002049ef536 468 Pfam PF01979 Amidohydrolase family 59 423 4.2E-70 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS09275 52f176b2c6a855f32f07ef9be7ddbbcc 825 Pfam PF02687 FtsX-like permease family 283 374 3.6E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS09275 52f176b2c6a855f32f07ef9be7ddbbcc 825 Pfam PF02687 FtsX-like permease family 726 816 4.4E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS09275 52f176b2c6a855f32f07ef9be7ddbbcc 825 Pfam PF12704 MacB-like periplasmic core domain 478 658 2.1E-9 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CWR56_RS09275 52f176b2c6a855f32f07ef9be7ddbbcc 825 Gene3D G3DSA:1.20.1250.20 352 815 0.1 T 29-03-2018 CWR56_RS09275 52f176b2c6a855f32f07ef9be7ddbbcc 825 Gene3D G3DSA:1.20.1250.20 3 351 0.007 T 29-03-2018 CWR56_RS05095 c02ede72f1becce5f483cdef8d2a22a1 65 Pfam PF01381 Helix-turn-helix 5 59 5.8E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS05095 c02ede72f1becce5f483cdef8d2a22a1 65 SUPERFAMILY SSF47413 2 64 5.9E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS05095 c02ede72f1becce5f483cdef8d2a22a1 65 SMART SM00530 4 59 4.6E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS05095 c02ede72f1becce5f483cdef8d2a22a1 65 Gene3D G3DSA:1.10.260.40 1 65 6.1E-20 T 29-03-2018 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 SUPERFAMILY SSF48208 272 752 1.7E-139 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 Gene3D G3DSA:2.60.420.10 685 756 1.7E-18 T 29-03-2018 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 323 699 4.4E-151 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 267 1.1E-54 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 703 753 1.1E-13 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 Gene3D G3DSA:2.70.98.40 5 270 8.2E-63 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 PIRSF PIRSF036289 1 761 4.6E-266 T 29-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 SUPERFAMILY SSF74650 6 269 2.45E-75 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS10560 f9bdb0d62b4041177092121873d28f6b 761 Gene3D G3DSA:1.50.10.10 317 684 3.4E-116 T 29-03-2018 CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 SUPERFAMILY SSF52540 165 553 4.91E-101 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 SUPERFAMILY SSF160246 3 141 1.44E-36 T 29-03-2018 CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 Gene3D G3DSA:3.40.50.300 304 557 2.6E-65 T 29-03-2018 CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 40 145 6.6E-27 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 Gene3D G3DSA:3.30.450.90 143 281 5.4E-45 T 29-03-2018 CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 Pfam PF00437 Type II/IV secretion system protein 183 448 5.9E-85 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 SMART SM00382 309 430 1.3E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17515 3a8471364904be86be2e3d222182b598 558 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 376 390 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR56_RS01030 3e9bc63c39fd4651cad79054fd1298f7 150 SUPERFAMILY SSF55804 11 144 4.45E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS01030 3e9bc63c39fd4651cad79054fd1298f7 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 11 144 1.8E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS01030 3e9bc63c39fd4651cad79054fd1298f7 150 Gene3D G3DSA:3.40.930.10 4 146 1.2E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS01030 3e9bc63c39fd4651cad79054fd1298f7 150 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 11 130 6.4E-33 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS10120 c5029dd1631ef7d8bdd0cb5221bfdc10 458 PIRSF PIRSF005353 1 458 1.1E-166 T 29-03-2018 IPR026033 Purine permease PbuG-like CWR56_RS10120 c5029dd1631ef7d8bdd0cb5221bfdc10 458 Pfam PF00860 Permease family 25 408 3.5E-40 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS10995 74682aefa7c99c3607fc0630eeab67c5 183 Gene3D G3DSA:3.40.630.30 4 183 1.8E-23 T 29-03-2018 CWR56_RS10995 74682aefa7c99c3607fc0630eeab67c5 183 SUPERFAMILY SSF55729 10 177 2.02E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS10995 74682aefa7c99c3607fc0630eeab67c5 183 Pfam PF13302 Acetyltransferase (GNAT) domain 17 153 2.0E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS13040 1dcf28efb9357fa9fb21bdb224c835c3 250 SMART SM00331 7 250 4.2E-30 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13040 1dcf28efb9357fa9fb21bdb224c835c3 250 SUPERFAMILY SSF81606 3 250 3.01E-62 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13040 1dcf28efb9357fa9fb21bdb224c835c3 250 Gene3D G3DSA:3.60.40.10 1 250 8.0E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS13040 1dcf28efb9357fa9fb21bdb224c835c3 250 Pfam PF13672 Protein phosphatase 2C 13 218 1.9E-18 T 29-03-2018 CWR56_RS13040 1dcf28efb9357fa9fb21bdb224c835c3 250 SMART SM00332 1 248 6.9E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS06670 e95859c925ecf56cd744b8db479c1bd0 277 SUPERFAMILY SSF55073 137 270 4.55E-23 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS06670 e95859c925ecf56cd744b8db479c1bd0 277 Gene3D G3DSA:3.30.70.270 115 275 7.6E-25 T 29-03-2018 CWR56_RS06670 e95859c925ecf56cd744b8db479c1bd0 277 Pfam PF00990 Diguanylate cyclase, GGDEF domain 133 271 3.5E-22 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06670 e95859c925ecf56cd744b8db479c1bd0 277 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 130 271 7.4E-23 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06670 e95859c925ecf56cd744b8db479c1bd0 277 SMART SM00267 121 272 2.3E-15 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS05415 6da684833b0254cda924fe8929c92364 241 Gene3D G3DSA:3.40.50.880 1 240 7.8E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS05415 6da684833b0254cda924fe8929c92364 241 Pfam PF07722 Peptidase C26 3 218 1.1E-66 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CWR56_RS05415 6da684833b0254cda924fe8929c92364 241 SUPERFAMILY SSF52317 25 239 2.79E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS11960 29de262ea5669725b121f389947d965c 398 SUPERFAMILY SSF47413 7 58 9.38E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS11960 29de262ea5669725b121f389947d965c 398 Pfam PF01381 Helix-turn-helix 12 56 2.4E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11960 29de262ea5669725b121f389947d965c 398 SMART SM00530 11 66 2.6E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS11960 29de262ea5669725b121f389947d965c 398 Pfam PF02486 Replication initiation factor 166 371 9.9E-70 T 29-03-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 CWR56_RS11960 29de262ea5669725b121f389947d965c 398 Gene3D G3DSA:3.30.1190.10 33 103 7.4E-4 T 29-03-2018 CWR56_RS11960 29de262ea5669725b121f389947d965c 398 Gene3D G3DSA:1.10.10.60 1 32 3.1E-7 T 29-03-2018 CWR56_RS09665 4c7736f9dff03c69ab36ae1564ff007b 124 SMART SM00345 17 76 2.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS09665 4c7736f9dff03c69ab36ae1564ff007b 124 SUPERFAMILY SSF46785 6 80 6.07E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09665 4c7736f9dff03c69ab36ae1564ff007b 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS09665 4c7736f9dff03c69ab36ae1564ff007b 124 Gene3D G3DSA:1.10.10.10 1 78 1.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00975 abce816ca9a9276076d6d616e033d7ef 244 Pfam PF01969 Protein of unknown function DUF111 6 242 3.8E-90 T 29-03-2018 IPR035108 LarC/UPF0272 CWR56_RS00975 abce816ca9a9276076d6d616e033d7ef 244 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 5 240 6.0E-74 T 29-03-2018 IPR002822 Uncharacterised protein family UPF0272 CWR56_RS02435 ef676627d10cb776984df47045e17ea6 303 SUPERFAMILY SSF46785 3 58 1.19E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02435 ef676627d10cb776984df47045e17ea6 303 Pfam PF13280 WYL domain 132 297 1.1E-36 T 29-03-2018 IPR026881 WYL domain CWR56_RS02435 ef676627d10cb776984df47045e17ea6 303 Pfam PF08279 HTH domain 5 56 1.3E-16 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS02435 ef676627d10cb776984df47045e17ea6 303 SMART SM00420 5 60 0.001 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS02435 ef676627d10cb776984df47045e17ea6 303 Gene3D G3DSA:1.10.10.10 1 63 1.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02435 ef676627d10cb776984df47045e17ea6 303 PIRSF PIRSF016838 1 302 5.0E-26 T 29-03-2018 IPR028349 Protein PafC CWR56_RS06900 5fc295fe3196629daa0d2d7add69e8f8 225 Gene3D G3DSA:3.40.50.300 1 223 4.9E-63 T 29-03-2018 CWR56_RS06900 5fc295fe3196629daa0d2d7add69e8f8 225 SUPERFAMILY SSF52540 3 221 1.55E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06900 5fc295fe3196629daa0d2d7add69e8f8 225 SMART SM00382 32 218 2.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06900 5fc295fe3196629daa0d2d7add69e8f8 225 Pfam PF00005 ABC transporter 23 169 3.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 Gene3D G3DSA:1.10.10.10 12 73 1.9E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 Gene3D G3DSA:3.30.420.40 74 209 8.5E-17 T 29-03-2018 CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 ProSitePatterns PS01125 ROK family signature. 220 247 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 SUPERFAMILY SSF53067 89 393 7.56E-43 T 29-03-2018 CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 Pfam PF00480 ROK family 99 392 5.2E-49 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 SUPERFAMILY SSF46785 13 79 1.04E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10590 56f7773bbeb36ad315a669b440f3ca13 404 Gene3D G3DSA:3.30.420.40 210 402 1.2E-34 T 29-03-2018 CWR56_RS13695 7eec1cd490d40a90f776767f87708e2e 622 Pfam PF08797 HIRAN domain 508 578 9.3E-10 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 CWR56_RS13695 7eec1cd490d40a90f776767f87708e2e 622 SMART SM00910 502 601 4.2E-21 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 CWR56_RS10815 7fc693d5d31adab0a0f4aea3ba09207e 282 SUPERFAMILY SSF46689 1 75 1.43E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS10815 7fc693d5d31adab0a0f4aea3ba09207e 282 Gene3D G3DSA:3.40.50.10490 71 281 1.3E-38 T 29-03-2018 CWR56_RS10815 7fc693d5d31adab0a0f4aea3ba09207e 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 3.4E-21 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR56_RS10815 7fc693d5d31adab0a0f4aea3ba09207e 282 SUPERFAMILY SSF53697 94 268 3.67E-42 T 29-03-2018 CWR56_RS10815 7fc693d5d31adab0a0f4aea3ba09207e 282 Gene3D G3DSA:1.10.10.10 1 70 6.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10815 7fc693d5d31adab0a0f4aea3ba09207e 282 Pfam PF01380 SIS domain 126 254 1.8E-29 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 16 128 2.8E-30 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Gene3D G3DSA:3.30.365.10 171 277 3.2E-30 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Gene3D G3DSA:3.30.365.10 609 768 1.0E-46 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 SMART SM01008 16 129 3.4E-46 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Gene3D G3DSA:3.30.365.10 450 608 4.3E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 SUPERFAMILY SSF56003 121 763 1.57E-178 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 701 2.2E-152 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Gene3D G3DSA:3.30.365.10 278 436 2.5E-44 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 Gene3D G3DSA:3.90.1170.50 1 129 3.4E-31 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS09940 91d16c027dbc78ba7d086e8623c4eac8 768 SUPERFAMILY SSF54665 2 145 5.36E-40 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 TIGRFAM TIGR00400 mgtE: magnesium transporter 12 459 2.7E-105 T 29-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Gene3D G3DSA:3.10.580.10 136 285 3.5E-23 T 29-03-2018 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Gene3D G3DSA:1.25.60.10 4 135 2.2E-12 T 29-03-2018 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 SUPERFAMILY SSF54631 140 276 1.14E-33 T 29-03-2018 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Pfam PF03448 MgtE intracellular N domain 38 138 1.0E-18 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Gene3D G3DSA:1.10.357.20 289 461 8.6E-29 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 SUPERFAMILY SSF161093 290 458 9.02E-36 T 29-03-2018 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Pfam PF01769 Divalent cation transporter 334 451 5.9E-22 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Pfam PF00571 CBS domain 204 258 1.7E-10 T 29-03-2018 IPR000644 CBS domain CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 Pfam PF00571 CBS domain 144 198 2.8E-9 T 29-03-2018 IPR000644 CBS domain CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 SUPERFAMILY SSF158791 12 137 3.92E-23 T 29-03-2018 CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 SMART SM00924 37 140 2.3E-23 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 SMART SM00116 211 259 5.4E-8 T 29-03-2018 IPR000644 CBS domain CWR56_RS12305 ae8c7286de6f282fd512f54aece071a0 462 SMART SM00116 147 200 0.0019 T 29-03-2018 IPR000644 CBS domain CWR56_RS16140 4777d99ba563ac2db69efb41bca8764b 83 Pfam PF12636 Protein of unknown function (DUF3781) 9 79 2.0E-34 T 29-03-2018 IPR024229 Protein of unknown function DUF3781 CWR56_RS16075 f13c29159fb75eb0bfe2011cbad6ac5c 281 Pfam PF00005 ABC transporter 18 160 9.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16075 f13c29159fb75eb0bfe2011cbad6ac5c 281 SUPERFAMILY SSF52540 2 221 4.46E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16075 f13c29159fb75eb0bfe2011cbad6ac5c 281 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16075 f13c29159fb75eb0bfe2011cbad6ac5c 281 SMART SM00382 27 216 8.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16075 f13c29159fb75eb0bfe2011cbad6ac5c 281 Gene3D G3DSA:3.40.50.300 1 252 1.2E-62 T 29-03-2018 CWR56_RS07710 ffca1e00f058a7e371f7c5d43c318e20 205 Pfam PF03413 Peptidase propeptide and YPEB domain 63 120 9.5E-9 T 29-03-2018 IPR025711 PepSY domain CWR56_RS07710 ffca1e00f058a7e371f7c5d43c318e20 205 Pfam PF03413 Peptidase propeptide and YPEB domain 145 202 9.2E-11 T 29-03-2018 IPR025711 PepSY domain CWR56_RS07710 ffca1e00f058a7e371f7c5d43c318e20 205 Gene3D G3DSA:3.10.450.40 145 202 1.7E-12 T 29-03-2018 CWR56_RS07710 ffca1e00f058a7e371f7c5d43c318e20 205 Gene3D G3DSA:3.10.450.40 65 123 2.1E-10 T 29-03-2018 CWR56_RS14460 fa59d0a81bd1f6c5413ee6990fc94e3e 135 Gene3D G3DSA:3.30.70.1290 1 129 9.1E-27 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS14460 fa59d0a81bd1f6c5413ee6990fc94e3e 135 SMART SM01321 10 130 6.2E-43 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS14460 fa59d0a81bd1f6c5413ee6990fc94e3e 135 Pfam PF01797 Transposase IS200 like 10 130 2.5E-42 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS14460 fa59d0a81bd1f6c5413ee6990fc94e3e 135 SUPERFAMILY SSF143422 2 131 4.58E-45 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS10980 e76d44e54467171367ea16a288b8a0c7 144 Pfam PF12663 Protein of unknown function (DUF3788) 10 136 2.2E-32 T 29-03-2018 IPR024265 Protein of unknown function DUF3788 CWR56_RS18930 e4f9dfa2e007e294c2d2d64bcbcd6098 154 Gene3D G3DSA:3.40.930.10 1 152 2.1E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS18930 e4f9dfa2e007e294c2d2d64bcbcd6098 154 SUPERFAMILY SSF55804 2 150 7.59E-39 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS18930 e4f9dfa2e007e294c2d2d64bcbcd6098 154 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 149 5.8E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS13985 9d8115d35d0203f5a1491ce152e96b3e 403 Pfam PF01734 Patatin-like phospholipase 4 189 1.6E-21 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CWR56_RS13985 9d8115d35d0203f5a1491ce152e96b3e 403 Gene3D G3DSA:3.40.1090.10 1 319 8.1E-27 T 29-03-2018 CWR56_RS13985 9d8115d35d0203f5a1491ce152e96b3e 403 SUPERFAMILY SSF52151 3 318 8.37E-39 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR56_RS08675 f20fdbd91cbcecb9d50fb27b1438e122 287 PIRSF PIRSF006483 1 287 4.1E-99 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS08675 f20fdbd91cbcecb9d50fb27b1438e122 287 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 2.8E-24 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CWR56_RS08675 f20fdbd91cbcecb9d50fb27b1438e122 287 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 221 3.1E-59 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR56_RS03195 77e07aea323ff4e0705ccc82b4e58dfb 129 Pfam PF03965 Penicillinase repressor 8 120 5.4E-24 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS03195 77e07aea323ff4e0705ccc82b4e58dfb 129 Gene3D G3DSA:1.10.10.10 7 71 4.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03195 77e07aea323ff4e0705ccc82b4e58dfb 129 PIRSF PIRSF019455 1 129 1.1E-32 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS03195 77e07aea323ff4e0705ccc82b4e58dfb 129 Gene3D G3DSA:1.10.4040.10 72 121 5.4E-10 T 29-03-2018 CWR56_RS03195 77e07aea323ff4e0705ccc82b4e58dfb 129 SUPERFAMILY SSF46785 4 124 6.46E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00035 02e1417ad30fe9cd9d1bf38e6e73419c 168 Pfam PF00466 Ribosomal protein L10 6 100 3.7E-28 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CWR56_RS00035 02e1417ad30fe9cd9d1bf38e6e73419c 168 Gene3D G3DSA:1.20.970.10 3 49 0.0049 T 29-03-2018 CWR56_RS00035 02e1417ad30fe9cd9d1bf38e6e73419c 168 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 19 145 0.003 T 29-03-2018 CWR56_RS00035 02e1417ad30fe9cd9d1bf38e6e73419c 168 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00035 02e1417ad30fe9cd9d1bf38e6e73419c 168 SUPERFAMILY SSF160369 4 161 7.19E-52 T 29-03-2018 CWR56_RS00035 02e1417ad30fe9cd9d1bf38e6e73419c 168 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 26.996 T 29-03-2018 IPR022973 Ribosomal protein L10 CWR56_RS11615 8494b4a8231fda6061e66f372b5c2fe7 306 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 25 291 7.3E-21 T 29-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 Gene3D G3DSA:3.40.630.10 1 249 7.1E-41 T 29-03-2018 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 Pfam PF07687 Peptidase dimerisation domain 181 276 2.0E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 PIRSF PIRSF005962 1 390 1.2E-103 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 374 9.9E-85 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 Pfam PF01546 Peptidase family M20/M25/M40 71 382 4.1E-26 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 Gene3D G3DSA:3.40.630.10 250 391 1.6E-12 T 29-03-2018 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 SUPERFAMILY SSF53187 2 196 5.09E-69 T 29-03-2018 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 SUPERFAMILY SSF53187 298 389 5.09E-69 T 29-03-2018 CWR56_RS09150 2986f7b96f0a67c062fbccf8877ad261 391 SUPERFAMILY SSF55031 184 289 1.44E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 SUPERFAMILY SSF54862 145 224 6.58E-16 T 29-03-2018 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 20 80 2.2E-15 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 Gene3D G3DSA:3.30.413.10 92 166 3.3E-19 T 29-03-2018 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 Gene3D G3DSA:3.30.413.10 190 301 5.6E-18 T 29-03-2018 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 Gene3D G3DSA:3.30.70.20 167 189 5.1E-4 T 29-03-2018 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 93 290 8.5E-30 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 SUPERFAMILY SSF56014 225 293 2.62E-40 T 29-03-2018 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 SUPERFAMILY SSF56014 91 165 2.62E-40 T 29-03-2018 CWR56_RS08650 099dd20aea2c6b4a34aa3290d5116787 315 SUPERFAMILY SSF55124 8 99 7.69E-18 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SUPERFAMILY SSF82185 73 166 3.79E-19 T 29-03-2018 CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SUPERFAMILY SSF82185 146 252 3.01E-31 T 29-03-2018 CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 222 240 6.8E-5 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 129 148 0.7 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 245 254 11.0 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 175 195 0.0012 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 199 219 3.7E-8 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 79 96 0.016 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 152 173 2.6E-8 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Pfam PF02493 MORN repeat 106 127 2.2E-5 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 197 218 7.5E-5 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 220 241 0.035 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 173 194 0.13 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 127 148 0.82 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 104 125 0.026 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 150 171 2.1E-6 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 SMART SM00698 77 98 0.75 T 29-03-2018 IPR003409 MORN motif CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Gene3D G3DSA:2.20.110.10 188 259 4.6E-23 T 29-03-2018 CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Gene3D G3DSA:2.20.110.10 134 187 1.0E-17 T 29-03-2018 CWR56_RS06780 72e4e26ec1700beafb12e5df71ff56a7 269 Gene3D G3DSA:2.20.110.10 61 133 8.6E-12 T 29-03-2018 CWR56_RS09115 619990ceefee28622a70755b7952fd71 209 PIRSF PIRSF010130 1 209 5.2E-93 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CWR56_RS09115 619990ceefee28622a70755b7952fd71 209 Pfam PF06130 Phosphate propanoyltransferase 23 102 1.2E-30 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CWR56_RS09115 619990ceefee28622a70755b7952fd71 209 Pfam PF06130 Phosphate propanoyltransferase 132 196 2.5E-18 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 265 2.0E-84 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 1.1E-37 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 98 5.5E-18 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 265 26.873 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 Gene3D G3DSA:1.10.3730.10 159 267 2.1E-42 T 29-03-2018 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 SUPERFAMILY SSF51735 2 159 3.17E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 221 243 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 PIRSF PIRSF000193 1 267 6.9E-85 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 Gene3D G3DSA:3.40.50.720 1 158 4.7E-27 T 29-03-2018 CWR56_RS07045 44fb9012cae988296bb2ae2a90260a3c 267 SUPERFAMILY SSF48179 160 266 2.21E-36 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 SMART SM00487 22 221 1.4E-53 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 Pfam PF03880 DbpA RNA binding domain 423 493 5.1E-16 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 Gene3D G3DSA:3.40.50.300 224 376 7.9E-45 T 29-03-2018 CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 Gene3D G3DSA:3.40.50.300 1 223 1.5E-53 T 29-03-2018 CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 SUPERFAMILY SSF52540 70 361 1.8E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 Pfam PF00270 DEAD/DEAH box helicase 28 191 6.0E-46 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 SMART SM00490 259 340 1.7E-30 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS10535 54d4a2be147ffd4aa89d231e77dc3fc0 497 Pfam PF00271 Helicase conserved C-terminal domain 235 340 3.9E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS04295 88102056013801b577d8ad41f4fbfee4 251 Pfam PF00005 ABC transporter 23 176 7.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04295 88102056013801b577d8ad41f4fbfee4 251 SMART SM00382 31 225 1.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS04295 88102056013801b577d8ad41f4fbfee4 251 Gene3D G3DSA:3.40.50.300 1 249 4.1E-55 T 29-03-2018 CWR56_RS04295 88102056013801b577d8ad41f4fbfee4 251 SUPERFAMILY SSF52540 1 231 6.71E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16120 19755d784f524059736752197f07358c 171 Pfam PF03551 Transcriptional regulator PadR-like family 6 77 4.3E-15 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR56_RS16120 19755d784f524059736752197f07358c 171 Pfam PF10400 Virulence activator alpha C-term 91 171 3.3E-7 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal CWR56_RS16120 19755d784f524059736752197f07358c 171 SUPERFAMILY SSF46785 2 170 1.06E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16120 19755d784f524059736752197f07358c 171 Gene3D G3DSA:1.10.10.10 1 90 1.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07870 764060851fd281d023562e0c9f70bdab 199 Gene3D G3DSA:2.60.60.30 19 184 4.9E-26 T 29-03-2018 CWR56_RS07870 764060851fd281d023562e0c9f70bdab 199 Pfam PF02342 TerD domain 1 124 7.5E-11 T 29-03-2018 IPR003325 TerD domain GO:0006950 CWR56_RS00265 8b182f835c7f7c317c2e24d3568cd5ec 130 SUPERFAMILY SSF54211 5 130 1.82E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS00265 8b182f835c7f7c317c2e24d3568cd5ec 130 Gene3D G3DSA:3.30.230.10 3 130 3.9E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS00265 8b182f835c7f7c317c2e24d3568cd5ec 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.571 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CWR56_RS00265 8b182f835c7f7c317c2e24d3568cd5ec 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.5E-46 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00265 8b182f835c7f7c317c2e24d3568cd5ec 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CWR56_RS02710 aff7e7b4b841e7fb54a828938e99eef7 409 SUPERFAMILY SSF55073 260 406 3.53E-31 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS02710 aff7e7b4b841e7fb54a828938e99eef7 409 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 407 1.1E-26 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02710 aff7e7b4b841e7fb54a828938e99eef7 409 Pfam PF00990 Diguanylate cyclase, GGDEF domain 256 405 2.1E-29 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02710 aff7e7b4b841e7fb54a828938e99eef7 409 SMART SM00267 244 409 3.9E-31 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02710 aff7e7b4b841e7fb54a828938e99eef7 409 Gene3D G3DSA:3.30.70.270 246 409 1.5E-33 T 29-03-2018 CWR56_RS06385 da0354760abe86a01074f7cc8d2111ce 142 Pfam PF10934 Protein of unknown function (DUF2634) 29 131 4.8E-33 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 CWR56_RS06385 da0354760abe86a01074f7cc8d2111ce 142 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 47 142 3.0E-19 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 CWR56_RS06385 da0354760abe86a01074f7cc8d2111ce 142 Gene3D G3DSA:3.10.450.40 19 141 1.6E-15 T 29-03-2018 CWR56_RS11610 a774665d8989cc532371b9b9061e297f 385 Pfam PF05816 Toxic anion resistance protein (TelA) 54 380 2.4E-127 T 29-03-2018 IPR008863 Toxic anion resistance CWR56_RS11610 a774665d8989cc532371b9b9061e297f 385 PIRSF PIRSF026508 18 385 7.3E-94 T 29-03-2018 IPR008863 Toxic anion resistance CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 SUPERFAMILY SSF53613 1 288 1.56E-65 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 Gene3D G3DSA:3.40.1190.20 42 309 6.2E-39 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 Pfam PF00294 pfkB family carbohydrate kinase 19 282 7.6E-52 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 Gene3D G3DSA:2.20.150.10 9 41 2.7E-10 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 306 3.8E-90 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 PIRSF PIRSF000535 1 308 6.6E-92 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 306 4.2E-97 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR56_RS17205 ecb2fdbf20ef3ccb40ac171ec470d745 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR56_RS14850 d5a586d1b95336e0c175bb9f30784d5c 248 SMART SM00382 31 219 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14850 d5a586d1b95336e0c175bb9f30784d5c 248 Gene3D G3DSA:3.40.50.300 1 239 7.0E-63 T 29-03-2018 CWR56_RS14850 d5a586d1b95336e0c175bb9f30784d5c 248 Pfam PF00005 ABC transporter 22 170 1.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS14850 d5a586d1b95336e0c175bb9f30784d5c 248 SUPERFAMILY SSF52540 3 223 6.63E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 Pfam PF08239 Bacterial SH3 domain 53 104 1.6E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 SMART SM00287 42 107 1.7E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 Pfam PF00877 NlpC/P60 family 126 226 5.0E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 SUPERFAMILY SSF54001 110 234 4.81E-44 T 29-03-2018 CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 Gene3D G3DSA:2.30.30.410 25 110 5.2E-18 T 29-03-2018 CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 SUPERFAMILY SSF50044 69 109 1.59E-5 T 29-03-2018 IPR001452 SH3 domain GO:0005515 CWR56_RS14040 2dff51ec9d0830a677411772292f542a 235 Gene3D G3DSA:3.90.1720.10 111 235 2.5E-41 T 29-03-2018 CWR56_RS15295 f3348a7ea4ff13f6999b5b5b046021e1 160 SUPERFAMILY SSF52728 6 159 8.89E-51 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS15295 f3348a7ea4ff13f6999b5b5b046021e1 160 Gene3D G3DSA:3.40.35.10 5 160 5.7E-54 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS15295 f3348a7ea4ff13f6999b5b5b046021e1 160 Pfam PF03830 PTS system sorbose subfamily IIB component 6 153 2.9E-50 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 108 134 1.4E-9 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 29 53 1.4E-9 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 55 79 1.4E-9 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 135 158 1.4E-9 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 SUPERFAMILY SSF81333 90 157 1.44E-11 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 Pfam PF00137 ATP synthase subunit C 97 155 2.0E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 Pfam PF00137 ATP synthase subunit C 17 75 1.6E-14 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 Gene3D G3DSA:1.20.120.610 6 163 9.3E-31 T 29-03-2018 CWR56_RS14720 ab2fbee9e29f86b810e9af8b6f668e75 163 SUPERFAMILY SSF81333 14 78 9.02E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR56_RS01940 123d70f28a85633f69a09663c72a3d25 451 Gene3D G3DSA:2.40.50.140 1 72 1.2E-13 T 29-03-2018 CWR56_RS01940 123d70f28a85633f69a09663c72a3d25 451 SUPERFAMILY SSF53335 68 450 2.05E-71 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS01940 123d70f28a85633f69a09663c72a3d25 451 Gene3D G3DSA:3.40.50.150 73 449 2.6E-53 T 29-03-2018 CWR56_RS01940 123d70f28a85633f69a09663c72a3d25 451 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 260 451 6.4E-18 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CWR56_RS01940 123d70f28a85633f69a09663c72a3d25 451 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CWR56_RS01940 123d70f28a85633f69a09663c72a3d25 451 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 443 2.1E-82 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 16 223 7.3E-32 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 333 472 9.7E-43 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 SUPERFAMILY SSF100950 13 231 1.26E-67 T 29-03-2018 CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 Gene3D G3DSA:3.40.1080.10 23 204 4.2E-35 T 29-03-2018 CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 22 504 1.4E-240 T 29-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 SUPERFAMILY SSF100950 238 505 1.29E-81 T 29-03-2018 CWR56_RS11645 126396252219e81630b571a3ebb93cd5 514 Gene3D G3DSA:3.40.1080.10 240 508 5.6E-58 T 29-03-2018 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 77 93 1.3E-44 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 111 131 1.3E-44 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 308 324 1.3E-44 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 265 283 1.3E-44 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 148 165 1.3E-44 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 397 412 1.3E-44 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 SUPERFAMILY SSF101821 89 216 2.29E-35 T 29-03-2018 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 13 430 2.8E-134 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 Gene3D G3DSA:2.30.250.10 101 204 2.5E-39 T 29-03-2018 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 Gene3D G3DSA:3.40.630.10 205 432 1.2E-77 T 29-03-2018 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 Gene3D G3DSA:3.40.630.10 2 100 1.4E-29 T 29-03-2018 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 SUPERFAMILY SSF53187 4 88 1.88E-99 T 29-03-2018 CWR56_RS01720 647ca3f42d981a90a00745ae130e8517 432 SUPERFAMILY SSF53187 216 431 1.88E-99 T 29-03-2018 CWR56_RS11060 ebfcfa622418578423523b4d09877280 816 PIRSF PIRSF015040 1 816 4.2E-255 T 29-03-2018 IPR016628 ATPase, SAG2001, predicted CWR56_RS11060 ebfcfa622418578423523b4d09877280 816 SUPERFAMILY SSF52540 411 798 4.6E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11060 ebfcfa622418578423523b4d09877280 816 Pfam PF12846 AAA-like domain 443 804 8.5E-154 T 29-03-2018 CWR56_RS11060 ebfcfa622418578423523b4d09877280 816 Gene3D G3DSA:3.40.50.300 465 789 8.7E-15 T 29-03-2018 CWR56_RS11640 c8af7f8c3f9df58923f76104984a9c63 463 Pfam PF00171 Aldehyde dehydrogenase family 3 414 3.4E-31 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS11640 c8af7f8c3f9df58923f76104984a9c63 463 SUPERFAMILY SSF53720 13 448 1.96E-66 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS11640 c8af7f8c3f9df58923f76104984a9c63 463 Gene3D G3DSA:3.40.605.10 2 234 5.0E-29 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS11640 c8af7f8c3f9df58923f76104984a9c63 463 Gene3D G3DSA:3.40.309.10 235 411 2.2E-25 T 29-03-2018 CWR56_RS16175 14442e35808118926dbace247d52415a 248 Gene3D G3DSA:2.20.25.110 145 207 2.9E-25 T 29-03-2018 CWR56_RS16175 14442e35808118926dbace247d52415a 248 Pfam PF13649 Methyltransferase domain 41 137 1.2E-20 T 29-03-2018 CWR56_RS16175 14442e35808118926dbace247d52415a 248 SUPERFAMILY SSF53335 4 248 4.48E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS16175 14442e35808118926dbace247d52415a 248 Gene3D G3DSA:3.40.50.150 1 141 4.9E-22 T 29-03-2018 CWR56_RS09575 cb4e1b8d888bd1930195ca72c212b7d2 218 SUPERFAMILY SSF46689 3 77 9.23E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09575 cb4e1b8d888bd1930195ca72c212b7d2 218 Gene3D G3DSA:1.10.10.60 2 47 3.3E-14 T 29-03-2018 CWR56_RS09575 cb4e1b8d888bd1930195ca72c212b7d2 218 Gene3D G3DSA:1.10.10.60 48 143 2.1E-11 T 29-03-2018 CWR56_RS09575 cb4e1b8d888bd1930195ca72c212b7d2 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS09575 cb4e1b8d888bd1930195ca72c212b7d2 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS09575 cb4e1b8d888bd1930195ca72c212b7d2 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 6.1E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 Gene3D G3DSA:1.10.1660.10 1 62 6.9E-19 T 29-03-2018 CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 Gene3D G3DSA:3.20.80.10 128 276 2.8E-15 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 SMART SM00422 5 75 1.0E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 Pfam PF13411 MerR HTH family regulatory protein 5 74 9.5E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 Gene3D G3DSA:1.10.1660.10 63 127 7.1E-9 T 29-03-2018 CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 SUPERFAMILY SSF46955 5 108 7.69E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 Pfam PF06445 GyrI-like small molecule binding domain 171 275 3.4E-6 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS17895 eed2ee2f775b8070d1dfd4fa616068c5 285 SUPERFAMILY SSF55136 122 274 3.66E-21 T 29-03-2018 CWR56_RS14510 b09f359acfe02c851cc095080d780592 339 Gene3D G3DSA:3.30.360.10 146 338 9.5E-31 T 29-03-2018 CWR56_RS14510 b09f359acfe02c851cc095080d780592 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 2.0E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CWR56_RS14510 b09f359acfe02c851cc095080d780592 339 SUPERFAMILY SSF55347 130 301 3.11E-26 T 29-03-2018 CWR56_RS14510 b09f359acfe02c851cc095080d780592 339 Gene3D G3DSA:3.40.50.720 1 145 5.9E-37 T 29-03-2018 CWR56_RS14510 b09f359acfe02c851cc095080d780592 339 SUPERFAMILY SSF51735 4 155 1.58E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 4 58 2.4E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 3 43 6.0E-6 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 4 64 13.192 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 PIRSF PIRSF006488 1 71 9.6E-19 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 SUPERFAMILY SSF116842 2 59 2.48E-18 T 29-03-2018 CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 Pfam PF02609 Exonuclease VII small subunit 5 56 6.2E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05495 7f9599b0669b31ca5928200b49664444 71 Gene3D G3DSA:1.10.287.1040 2 67 1.9E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS14685 0fa585963b32da983eaf8fee9423155b 349 PIRSF PIRSF002825 1 343 1.8E-82 T 29-03-2018 IPR026045 Ferric binding protein CWR56_RS14685 0fa585963b32da983eaf8fee9423155b 349 SUPERFAMILY SSF53850 32 339 3.66E-67 T 29-03-2018 CWR56_RS14685 0fa585963b32da983eaf8fee9423155b 349 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 22 347 3.3E-123 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative CWR56_RS14685 0fa585963b32da983eaf8fee9423155b 349 Pfam PF13343 Bacterial extracellular solute-binding protein 83 308 4.5E-31 T 29-03-2018 CWR56_RS14685 0fa585963b32da983eaf8fee9423155b 349 Gene3D G3DSA:3.40.190.10 31 148 7.8E-13 T 29-03-2018 CWR56_RS14685 0fa585963b32da983eaf8fee9423155b 349 Gene3D G3DSA:3.40.190.10 149 304 1.6E-33 T 29-03-2018 CWR56_RS11920 2ad200b92b34e3cd27d537865f49876c 816 Pfam PF12846 AAA-like domain 443 804 3.7E-153 T 29-03-2018 CWR56_RS11920 2ad200b92b34e3cd27d537865f49876c 816 SUPERFAMILY SSF52540 412 798 9.96E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11920 2ad200b92b34e3cd27d537865f49876c 816 PIRSF PIRSF015040 1 816 6.9E-253 T 29-03-2018 IPR016628 ATPase, SAG2001, predicted CWR56_RS11920 2ad200b92b34e3cd27d537865f49876c 816 Gene3D G3DSA:3.40.50.300 465 788 6.0E-15 T 29-03-2018 CWR56_RS17345 f96d9164c3e5d651a886e5540beb2b18 209 SUPERFAMILY SSF53271 4 207 1.7E-73 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS17345 f96d9164c3e5d651a886e5540beb2b18 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.9E-92 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWR56_RS17345 f96d9164c3e5d651a886e5540beb2b18 209 Gene3D G3DSA:3.40.50.2020 2 207 1.2E-65 T 29-03-2018 CWR56_RS17345 f96d9164c3e5d651a886e5540beb2b18 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.733 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWR56_RS17345 f96d9164c3e5d651a886e5540beb2b18 209 Pfam PF14681 Uracil phosphoribosyltransferase 7 208 1.6E-76 T 29-03-2018 CWR56_RS14345 0bd2372d5bd889ad466486325f19af9f 364 SUPERFAMILY SSF51395 4 361 1.5E-62 T 29-03-2018 CWR56_RS14345 0bd2372d5bd889ad466486325f19af9f 364 Gene3D G3DSA:3.20.20.70 1 364 1.6E-65 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS14345 0bd2372d5bd889ad466486325f19af9f 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 337 1.5E-43 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CWR56_RS10260 65932af57c4a159ed73239fd6657a842 67 SUPERFAMILY SSF47413 7 65 1.5E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS10260 65932af57c4a159ed73239fd6657a842 67 Gene3D G3DSA:1.10.260.40 7 67 7.9E-7 T 29-03-2018 CWR56_RS10260 65932af57c4a159ed73239fd6657a842 67 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 64 2.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 Gene3D G3DSA:1.10.3860.10 1 353 2.7E-70 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 SUPERFAMILY SSF118215 13 353 1.7E-68 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 Pfam PF00375 Sodium:dicarboxylate symporter family 15 352 7.9E-73 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 1.8E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.8E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 1.8E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 1.8E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS10475 15b18108625c22e1a55d0c53b75d35ff 353 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.8E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 492 626 1.1E-18 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 SUPERFAMILY SSF55804 489 627 7.06E-25 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Gene3D G3DSA:3.40.50.2300 389 475 3.8E-11 T 29-03-2018 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Gene3D G3DSA:1.10.1790.10 278 383 5.5E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Gene3D G3DSA:1.10.10.10 81 149 7.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 SUPERFAMILY SSF63520 279 379 2.22E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 SUPERFAMILY SSF52794 390 468 1.26E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Gene3D G3DSA:1.10.10.10 1 63 2.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Gene3D G3DSA:3.40.930.10 490 628 1.8E-19 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Pfam PF00874 PRD domain 291 377 1.2E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Pfam PF05043 Mga helix-turn-helix domain 86 156 1.6E-6 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS17185 184637afe8a8f2392f874221c1a28789 633 Pfam PF08279 HTH domain 2 60 2.8E-9 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS05470 994778eabbc5a46177b4678b1a5ed075 229 Pfam PF12685 SpoIIIAH-like protein 10 221 2.9E-42 T 29-03-2018 IPR024232 Stage III sporulation protein AH-like CWR56_RS18400 ac9b3bf7a0f746393acb66ea3cec40da 239 Gene3D G3DSA:3.40.50.150 2 239 1.7E-37 T 29-03-2018 CWR56_RS18400 ac9b3bf7a0f746393acb66ea3cec40da 239 Pfam PF02527 rRNA small subunit methyltransferase G 23 195 5.9E-54 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR56_RS18400 ac9b3bf7a0f746393acb66ea3cec40da 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 216 8.0E-55 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR56_RS18400 ac9b3bf7a0f746393acb66ea3cec40da 239 PIRSF PIRSF003078 2 221 3.8E-54 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR56_RS18400 ac9b3bf7a0f746393acb66ea3cec40da 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 215 28.553 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR56_RS18400 ac9b3bf7a0f746393acb66ea3cec40da 239 SUPERFAMILY SSF53335 5 238 3.95E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS05460 4d022c10979b22206f7978675f12c390 205 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 16 203 9.4E-27 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 Gene3D G3DSA:3.40.50.2300 3 119 4.8E-32 T 29-03-2018 CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 4.6E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 SUPERFAMILY SSF52172 6 189 1.99E-37 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 SMART SM00448 5 116 1.7E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 Pfam PF00072 Response regulator receiver domain 7 117 9.6E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 SMART SM00862 155 231 3.8E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS02385 d2a6a44cb21522e16f89e9cc32b9536e 234 Gene3D G3DSA:1.10.10.10 120 234 1.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 Gene3D G3DSA:3.30.420.40 1 193 9.1E-53 T 29-03-2018 CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 Gene3D G3DSA:3.30.420.40 250 381 7.5E-17 T 29-03-2018 CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 SUPERFAMILY SSF53067 147 333 7.77E-14 T 29-03-2018 CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 SUPERFAMILY SSF53067 67 112 7.77E-14 T 29-03-2018 CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 SUPERFAMILY SSF53067 1 35 7.77E-14 T 29-03-2018 CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 378 5.2E-101 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CWR56_RS15210 8e2718794e817fe4bbcecb115d398f0d 383 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 378 36.073 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CWR56_RS01650 c52c76d61bd053f00fe4dc129b42289d 257 Pfam PF12730 ABC-2 family transporter protein 4 198 1.2E-58 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 SUPERFAMILY SSF53187 15 188 2.51E-59 T 29-03-2018 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 SUPERFAMILY SSF53187 288 379 2.51E-59 T 29-03-2018 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 PIRSF PIRSF037226 2 381 1.9E-130 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 Gene3D G3DSA:3.40.630.10 4 297 4.3E-42 T 29-03-2018 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 Gene3D G3DSA:3.40.630.10 311 381 1.9E-7 T 29-03-2018 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 Pfam PF07687 Peptidase dimerisation domain 176 267 2.6E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 Pfam PF01546 Peptidase family M20/M25/M40 88 360 1.4E-10 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 353 4.1E-64 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS03785 c7504ecae2608ee86ee4723603251527 381 SUPERFAMILY SSF55031 176 280 7.33E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS12520 37a00bd1bbc3f1a33b7e1fc3f6cf0356 301 PIRSF PIRSF018688 1 301 5.3E-84 T 29-03-2018 IPR016732 Uncharacterised conserved protein UCP018688 CWR56_RS12520 37a00bd1bbc3f1a33b7e1fc3f6cf0356 301 Gene3D G3DSA:3.40.630.30 127 293 6.1E-62 T 29-03-2018 CWR56_RS12520 37a00bd1bbc3f1a33b7e1fc3f6cf0356 301 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 20 298 6.1E-43 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CWR56_RS12520 37a00bd1bbc3f1a33b7e1fc3f6cf0356 301 SUPERFAMILY SSF55729 135 299 6.71E-56 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS12520 37a00bd1bbc3f1a33b7e1fc3f6cf0356 301 Gene3D G3DSA:3.40.630.30 1 126 9.3E-36 T 29-03-2018 CWR56_RS12520 37a00bd1bbc3f1a33b7e1fc3f6cf0356 301 SUPERFAMILY SSF55729 3 134 1.17E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS15030 602cf89a9325eefdc6ffe53f74e0c2a5 106 SUPERFAMILY SSF52794 4 101 2.35E-34 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15030 602cf89a9325eefdc6ffe53f74e0c2a5 106 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 6 90 1.0E-30 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS15030 602cf89a9325eefdc6ffe53f74e0c2a5 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 7 97 2.5E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15030 602cf89a9325eefdc6ffe53f74e0c2a5 106 Gene3D G3DSA:3.40.50.2300 4 102 1.8E-38 T 29-03-2018 CWR56_RS03800 d036923418dba282d06530d7917be529 188 Pfam PF13305 WHG domain 84 160 3.2E-8 T 29-03-2018 IPR025996 WHG domain CWR56_RS03800 d036923418dba282d06530d7917be529 188 SUPERFAMILY SSF46689 8 72 6.67E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS03800 d036923418dba282d06530d7917be529 188 Gene3D G3DSA:1.10.357.10 1 124 1.3E-6 T 29-03-2018 CWR56_RS11580 577e9d10829c6ef796a6a4ee2290a214 190 SUPERFAMILY SSF53271 1 187 8.52E-40 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS11580 577e9d10829c6ef796a6a4ee2290a214 190 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 188 8.5E-66 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CWR56_RS11580 577e9d10829c6ef796a6a4ee2290a214 190 Pfam PF00156 Phosphoribosyl transferase domain 35 158 1.3E-9 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS11580 577e9d10829c6ef796a6a4ee2290a214 190 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 190 39.755 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CWR56_RS11580 577e9d10829c6ef796a6a4ee2290a214 190 Gene3D G3DSA:3.40.50.2020 3 189 5.4E-22 T 29-03-2018 CWR56_RS01460 1b45b4e2428638e7ef0e8ee8ef2de1e3 165 SUPERFAMILY SSF52728 4 160 1.31E-40 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS01460 1b45b4e2428638e7ef0e8ee8ef2de1e3 165 Gene3D G3DSA:3.40.35.10 3 158 3.1E-46 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS01460 1b45b4e2428638e7ef0e8ee8ef2de1e3 165 Pfam PF03830 PTS system sorbose subfamily IIB component 4 149 4.4E-44 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS14670 34229586d0062782e77f4925b9607351 384 Pfam PF00990 Diguanylate cyclase, GGDEF domain 229 379 5.5E-30 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14670 34229586d0062782e77f4925b9607351 384 Gene3D G3DSA:3.30.450.20 37 192 1.1E-4 T 29-03-2018 CWR56_RS14670 34229586d0062782e77f4925b9607351 384 SMART SM00267 218 384 1.8E-20 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14670 34229586d0062782e77f4925b9607351 384 SUPERFAMILY SSF55073 234 379 5.73E-30 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS14670 34229586d0062782e77f4925b9607351 384 Gene3D G3DSA:3.30.70.270 224 384 6.2E-36 T 29-03-2018 CWR56_RS14670 34229586d0062782e77f4925b9607351 384 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 228 381 7.0E-29 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 SUPERFAMILY SSF53187 5 176 3.39E-62 T 29-03-2018 CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 SUPERFAMILY SSF53187 287 367 3.39E-62 T 29-03-2018 CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 Pfam PF01546 Peptidase family M20/M25/M40 105 367 6.5E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 SUPERFAMILY SSF55031 179 288 1.26E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 366 5.4E-93 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 Pfam PF07687 Peptidase dimerisation domain 180 273 6.1E-14 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS02405 6fb3b50343e8d53ae261a860a13e6144 368 Gene3D G3DSA:3.40.630.10 2 368 3.3E-62 T 29-03-2018 CWR56_RS09290 34e1f49e4ee2bb79598435e3fd23eee0 185 Pfam PF13302 Acetyltransferase (GNAT) domain 18 157 1.6E-27 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS09290 34e1f49e4ee2bb79598435e3fd23eee0 185 SUPERFAMILY SSF55729 7 178 4.03E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS09290 34e1f49e4ee2bb79598435e3fd23eee0 185 Gene3D G3DSA:3.40.630.30 1 181 4.9E-21 T 29-03-2018 CWR56_RS15575 eb7fe1fb6544642cf8f8089920500fa7 134 Pfam PF11337 Protein of unknown function (DUF3139) 1 84 4.6E-15 T 29-03-2018 IPR021486 Protein of unknown function DUF3139 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 SUPERFAMILY SSF69189 274 370 1.71E-17 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 262 8.7E-73 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 282 372 4.3E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 SMART SM00936 282 372 1.3E-21 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 3.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 3.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 117 134 3.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 SUPERFAMILY SSF56601 4 282 2.46E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS05985 985063e3514bd551e525423b84234a48 387 Gene3D G3DSA:3.40.710.10 23 281 2.9E-49 T 29-03-2018 CWR56_RS05985 985063e3514bd551e525423b84234a48 387 Gene3D G3DSA:2.60.410.10 282 372 4.4E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Pfam PF13475 Domain of unknown function (DUF4116) 251 291 1.3E-6 T 29-03-2018 IPR025197 Domain of unknown function DUF4116 CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 432 476 1.4E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 366 398 4.0E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 294 365 2.0E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 399 431 5.2E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 107 206 9.2E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 207 249 1.3E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 24 106 1.0E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS13955 43ba09d3e81ce1b6e0ecb6f1f5287ac1 476 Gene3D G3DSA:2.60.40.10 250 293 9.8E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 SUPERFAMILY SSF53383 5 379 3.72E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 PIRSF PIRSF005572 3 384 7.1E-133 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 Gene3D G3DSA:3.90.1150.10 266 384 6.8E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 395 51.743 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 Gene3D G3DSA:3.40.640.10 14 259 1.1E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 Pfam PF00266 Aminotransferase class-V 7 368 4.0E-88 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWR56_RS05925 45b9b7558cdb9a5a9e0359d489b27e88 397 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 7 386 2.5E-182 T 29-03-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR56_RS03910 67ccaa7374e08b8d10ae47f785836c95 260 Gene3D G3DSA:3.90.226.10 6 217 3.0E-76 T 29-03-2018 CWR56_RS03910 67ccaa7374e08b8d10ae47f785836c95 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CWR56_RS03910 67ccaa7374e08b8d10ae47f785836c95 260 SUPERFAMILY SSF52096 3 259 3.32E-89 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS03910 67ccaa7374e08b8d10ae47f785836c95 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 259 2.9E-75 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CWR56_RS03910 67ccaa7374e08b8d10ae47f785836c95 260 Gene3D G3DSA:1.10.12.10 218 260 3.1E-19 T 29-03-2018 IPR014748 Crontonase, C-terminal CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 75 21.75 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 Pfam PF01084 Ribosomal protein S18 19 70 2.2E-26 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 Gene3D G3DSA:4.10.640.10 1 75 2.5E-31 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 75 3.0E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 SUPERFAMILY SSF46911 4 74 2.35E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 PRINTS PR00974 Ribosomal protein S18 family signature 30 40 3.8E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 PRINTS PR00974 Ribosomal protein S18 family signature 62 72 3.8E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 PRINTS PR00974 Ribosomal protein S18 family signature 40 47 3.8E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 PRINTS PR00974 Ribosomal protein S18 family signature 48 62 3.8E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 23 46 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS18335 3d484033308f085d4eebdbe22539bdc7 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 7 73 2.1E-31 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS06080 fc2799ab76ac07259101af7382068f10 103 Gene3D G3DSA:3.30.1330.30 2 102 9.0E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CWR56_RS06080 fc2799ab76ac07259101af7382068f10 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 97 4.8E-14 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CWR56_RS06080 fc2799ab76ac07259101af7382068f10 103 SUPERFAMILY SSF55315 6 101 5.8E-26 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CWR56_RS17505 7d20369c7fe8aa66cca9f7540e1c509d 570 Pfam PF05137 Fimbrial assembly protein (PilN) 408 560 2.2E-5 T 29-03-2018 IPR007813 Fimbrial assembly PilN CWR56_RS17505 7d20369c7fe8aa66cca9f7540e1c509d 570 Gene3D G3DSA:3.30.420.40 13 163 1.9E-7 T 29-03-2018 CWR56_RS17505 7d20369c7fe8aa66cca9f7540e1c509d 570 SUPERFAMILY SSF53067 59 160 5.44E-6 T 29-03-2018 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 Pfam PF08281 Sigma-70, region 4 97 148 8.0E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 Pfam PF04542 Sigma-70 region 2 15 74 2.9E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 SUPERFAMILY SSF88659 89 153 8.04E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 152 5.2E-23 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 SUPERFAMILY SSF88946 7 78 5.49E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 Gene3D G3DSA:1.10.1740.10 2 77 1.3E-13 T 29-03-2018 CWR56_RS03225 3be4230d3e705d337dea97437b3d73ee 159 Gene3D G3DSA:1.10.10.10 81 158 1.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08435 c1a0eb1583b927c7d938fc0d18379102 87 SUPERFAMILY SSF47413 3 66 2.35E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS08435 c1a0eb1583b927c7d938fc0d18379102 87 SMART SM00530 4 59 4.8E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS08435 c1a0eb1583b927c7d938fc0d18379102 87 Gene3D G3DSA:1.10.3100.10 1 87 1.2E-17 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS08435 c1a0eb1583b927c7d938fc0d18379102 87 Pfam PF01381 Helix-turn-helix 5 57 6.4E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15700 886e50776f7aa0a6ee424ebabe527d9e 190 Gene3D G3DSA:2.40.260.10 46 190 2.2E-41 T 29-03-2018 IPR023365 Sortase domain CWR56_RS15700 886e50776f7aa0a6ee424ebabe527d9e 190 SUPERFAMILY SSF63817 7 187 2.35E-37 T 29-03-2018 IPR023365 Sortase domain CWR56_RS15700 886e50776f7aa0a6ee424ebabe527d9e 190 Pfam PF04203 Sortase family 65 165 1.2E-13 T 29-03-2018 IPR005754 Sortase family CWR56_RS08765 5e247ef0adf3215abe82043db67f36b7 198 Pfam PF01553 Acyltransferase 22 145 6.7E-25 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWR56_RS08765 5e247ef0adf3215abe82043db67f36b7 198 SUPERFAMILY SSF69593 5 193 9.81E-47 T 29-03-2018 CWR56_RS08765 5e247ef0adf3215abe82043db67f36b7 198 SMART SM00563 35 148 1.1E-30 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWR56_RS08765 5e247ef0adf3215abe82043db67f36b7 198 Gene3D G3DSA:3.40.1130.10 1 198 2.3E-39 T 29-03-2018 CWR56_RS08765 5e247ef0adf3215abe82043db67f36b7 198 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 20 145 2.1E-31 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 SUPERFAMILY SSF109604 96 173 5.89E-9 T 29-03-2018 CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 SUPERFAMILY SSF109604 34 65 5.89E-9 T 29-03-2018 CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 Pfam PF01966 HD domain 34 109 7.3E-5 T 29-03-2018 IPR006674 HD domain CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 Pfam PF00271 Helicase conserved C-terminal domain 521 623 1.6E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 Gene3D G3DSA:1.10.3210.10 3 266 7.1E-10 T 29-03-2018 CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 Gene3D G3DSA:3.40.50.300 280 462 2.9E-5 T 29-03-2018 CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 Gene3D G3DSA:3.40.50.300 500 696 1.5E-16 T 29-03-2018 CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 SMART SM00490 540 624 9.8E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 299 654 8.9E-53 T 29-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 SUPERFAMILY SSF52540 292 337 3.23E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 SUPERFAMILY SSF52540 389 462 3.23E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 SUPERFAMILY SSF52540 492 639 3.23E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS12385 5e79955d8df134c80485d2d9e2686ca8 802 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 25 244 2.0E-25 T 29-03-2018 IPR006483 CRISPR-associated Cas3-HD domain CWR56_RS18075 50724fc12d5d4bc26b309db34835c256 149 SUPERFAMILY SSF55729 10 144 1.57E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS18075 50724fc12d5d4bc26b309db34835c256 149 Pfam PF13673 Acetyltransferase (GNAT) domain 32 135 2.8E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS18075 50724fc12d5d4bc26b309db34835c256 149 Gene3D G3DSA:3.40.630.30 5 148 3.5E-16 T 29-03-2018 CWR56_RS09000 385608e332a4c71b004e55e50636ec33 145 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 76 111 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR56_RS09000 385608e332a4c71b004e55e50636ec33 145 PIRSF PIRSF006019 1 145 1.6E-51 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR56_RS09000 385608e332a4c71b004e55e50636ec33 145 SUPERFAMILY SSF53927 13 143 6.38E-39 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS09000 385608e332a4c71b004e55e50636ec33 145 Gene3D G3DSA:3.40.140.10 1 143 1.9E-37 T 29-03-2018 CWR56_RS09000 385608e332a4c71b004e55e50636ec33 145 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 121 2.4E-28 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR56_RS10860 ee9eb3f10526aa9235cb3dee577f4948 391 SUPERFAMILY SSF55073 233 391 1.57E-36 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS10860 ee9eb3f10526aa9235cb3dee577f4948 391 Pfam PF00990 Diguanylate cyclase, GGDEF domain 229 386 2.8E-38 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS10860 ee9eb3f10526aa9235cb3dee577f4948 391 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 226 388 3.6E-39 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS10860 ee9eb3f10526aa9235cb3dee577f4948 391 SMART SM00267 217 391 1.4E-34 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS10860 ee9eb3f10526aa9235cb3dee577f4948 391 Gene3D G3DSA:3.30.70.270 211 391 6.9E-40 T 29-03-2018 CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 SUPERFAMILY SSF52743 24 305 2.62E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 Pfam PF00082 Subtilase family 43 298 2.0E-56 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 48 59 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 89 99 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 PRINTS PR00723 Subtilisin serine protease family (S8) signature 43 62 7.6E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 PRINTS PR00723 Subtilisin serine protease family (S8) signature 85 98 7.6E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 PRINTS PR00723 Subtilisin serine protease family (S8) signature 244 260 7.6E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 245 255 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CWR56_RS09590 5b30f50805e29b3a3b0efe0000dbe29a 313 Gene3D G3DSA:3.40.50.200 7 307 6.1E-90 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 Pfam PF01409 tRNA synthetases class II core domain (F) 93 339 6.2E-103 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 339 47.573 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 SUPERFAMILY SSF46589 13 99 2.72E-20 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 Gene3D G3DSA:3.30.930.10 8 339 3.7E-97 T 29-03-2018 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 1.5E-24 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 SUPERFAMILY SSF55681 93 339 2.49E-84 T 29-03-2018 CWR56_RS03360 f1eedd147f53f95940724485505d615b 339 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 339 1.3E-105 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 Pfam PF07690 Major Facilitator Superfamily 12 348 8.5E-58 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 Gene3D G3DSA:1.20.1250.20 194 387 5.3E-26 T 29-03-2018 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 SUPERFAMILY SSF103473 4 386 1.57E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 73 97 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 272 293 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 131 153 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 159 179 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 16 32 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 244 264 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 PRINTS PR01035 Tetracycline resistance protein signature 332 355 1.0E-27 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR56_RS11030 bb46f54bf9a52903e7b8d8fe24acb1f1 387 Gene3D G3DSA:1.20.1250.20 1 193 9.9E-42 T 29-03-2018 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 342 353 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 SUPERFAMILY SSF51395 1 292 2.75E-69 T 29-03-2018 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 Gene3D G3DSA:3.30.70.20 344 368 3.3E-5 T 29-03-2018 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 Gene3D G3DSA:3.30.70.20 322 343 8.2E-12 T 29-03-2018 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 Pfam PF12838 4Fe-4S dicluster domain 313 356 6.8E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 Gene3D G3DSA:3.20.20.70 1 289 1.1E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 Gene3D G3DSA:1.10.1060.10 290 321 8.9E-4 T 29-03-2018 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 Pfam PF01180 Dihydroorotate dehydrogenase 4 276 2.5E-39 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 SUPERFAMILY SSF54862 297 359 2.72E-15 T 29-03-2018 CWR56_RS15960 d81305f1ad9e0011b2c58f1a9959cd69 369 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 292 3.0E-61 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR56_RS00560 82e6e0c173c69cd45dd1abbf310e1174 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 6 177 1.8E-23 T 29-03-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CWR56_RS00560 82e6e0c173c69cd45dd1abbf310e1174 185 SUPERFAMILY SSF53323 5 180 2.35E-44 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CWR56_RS00560 82e6e0c173c69cd45dd1abbf310e1174 185 Gene3D G3DSA:3.40.920.10 1 184 4.2E-49 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS00560 82e6e0c173c69cd45dd1abbf310e1174 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 177 1.2E-36 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS09380 e100aff1e4b10f25a1fcb4a1c7b92d8d 183 SUPERFAMILY SSF55826 23 182 1.44E-41 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS09380 e100aff1e4b10f25a1fcb4a1c7b92d8d 183 Pfam PF04073 Aminoacyl-tRNA editing domain 44 167 1.9E-24 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS09380 e100aff1e4b10f25a1fcb4a1c7b92d8d 183 Gene3D G3DSA:3.90.960.10 10 183 9.3E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS04565 62d32f2c7655defc3deeef25d7cf3785 182 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 174 2.8E-51 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CWR56_RS04565 62d32f2c7655defc3deeef25d7cf3785 182 Pfam PF05683 Fumarase C-terminus 4 174 3.4E-57 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CWR56_RS04565 62d32f2c7655defc3deeef25d7cf3785 182 Gene3D G3DSA:3.20.130.10 1 173 3.8E-70 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CWR56_RS04565 62d32f2c7655defc3deeef25d7cf3785 182 SUPERFAMILY SSF117457 4 173 3.14E-60 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CWR56_RS04205 d077f4a92dd39338bc6335ac078a599d 522 SUPERFAMILY SSF53850 34 513 2.17E-123 T 29-03-2018 CWR56_RS04205 d077f4a92dd39338bc6335ac078a599d 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 437 8.1E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CWR56_RS04205 d077f4a92dd39338bc6335ac078a599d 522 Gene3D G3DSA:3.10.105.10 278 485 6.5E-49 T 29-03-2018 CWR56_RS04205 d077f4a92dd39338bc6335ac078a599d 522 Gene3D G3DSA:3.90.76.10 46 186 1.9E-40 T 29-03-2018 CWR56_RS04205 d077f4a92dd39338bc6335ac078a599d 522 Gene3D G3DSA:3.40.190.10 187 277 5.6E-26 T 29-03-2018 CWR56_RS04205 d077f4a92dd39338bc6335ac078a599d 522 PIRSF PIRSF002741 1 517 1.8E-125 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWR56_RS13010 85c9eddd75a1dc4bd3cabf957c52f94b 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 181 1.2E-23 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS13010 85c9eddd75a1dc4bd3cabf957c52f94b 209 Gene3D G3DSA:3.40.50.1000 2 205 1.4E-20 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS13010 85c9eddd75a1dc4bd3cabf957c52f94b 209 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 173 1.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS13010 85c9eddd75a1dc4bd3cabf957c52f94b 209 SUPERFAMILY SSF56784 4 204 4.6E-36 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS12320 d1b3a0fad9ff39415a8da1d4df91edcd 239 Gene3D G3DSA:1.10.3830.10 7 118 3.0E-36 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWR56_RS12320 d1b3a0fad9ff39415a8da1d4df91edcd 239 SUPERFAMILY SSF48317 56 234 7.3E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS12320 d1b3a0fad9ff39415a8da1d4df91edcd 239 Gene3D G3DSA:1.20.144.10 134 234 3.5E-12 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS12320 d1b3a0fad9ff39415a8da1d4df91edcd 239 Pfam PF01569 PAP2 superfamily 161 234 8.4E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS12320 d1b3a0fad9ff39415a8da1d4df91edcd 239 Pfam PF01219 Prokaryotic diacylglycerol kinase 16 116 5.1E-33 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 Gene3D G3DSA:3.40.50.2000 12 260 8.1E-9 T 29-03-2018 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 Pfam PF08323 Starch synthase catalytic domain 2 241 5.2E-87 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 Gene3D G3DSA:3.40.50.2000 261 474 1.3E-32 T 29-03-2018 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 SUPERFAMILY SSF53756 2 480 2.01E-124 T 29-03-2018 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 477 4.2E-169 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 Hamap MF_00484 Glycogen synthase [glgA]. 1 478 44.912 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CWR56_RS04345 c1109cf56fe97e95c2862bf6632c850c 480 Pfam PF00534 Glycosyl transferases group 1 295 454 8.8E-13 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CWR56_RS18085 7c5898d730be32c2800bff5f5ab9f6ab 288 SUPERFAMILY SSF141571 64 97 6.02E-19 T 29-03-2018 CWR56_RS18085 7c5898d730be32c2800bff5f5ab9f6ab 288 SUPERFAMILY SSF141571 190 279 6.02E-19 T 29-03-2018 CWR56_RS18085 7c5898d730be32c2800bff5f5ab9f6ab 288 Gene3D G3DSA:2.160.20.80 50 276 1.5E-23 T 29-03-2018 CWR56_RS18085 7c5898d730be32c2800bff5f5ab9f6ab 288 Pfam PF00805 Pentapeptide repeats (8 copies) 203 221 0.011 T 29-03-2018 IPR001646 Pentapeptide repeat CWR56_RS18085 7c5898d730be32c2800bff5f5ab9f6ab 288 Pfam PF00805 Pentapeptide repeats (8 copies) 226 259 1.8E-10 T 29-03-2018 IPR001646 Pentapeptide repeat CWR56_RS02615 49d8cbea80a0d06e4bce211abb2b2af3 156 SUPERFAMILY SSF75217 3 155 2.42E-43 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR56_RS02615 49d8cbea80a0d06e4bce211abb2b2af3 156 PIRSF PIRSF029256 2 156 9.6E-65 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWR56_RS02615 49d8cbea80a0d06e4bce211abb2b2af3 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 155 1.6E-61 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWR56_RS02615 49d8cbea80a0d06e4bce211abb2b2af3 156 Gene3D G3DSA:3.40.1280.10 1 156 6.0E-39 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR56_RS02615 49d8cbea80a0d06e4bce211abb2b2af3 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 153 34.621 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWR56_RS02615 49d8cbea80a0d06e4bce211abb2b2af3 156 Pfam PF00588 SpoU rRNA Methylase family 3 144 1.6E-34 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWR56_RS01355 0feb49587add3f9cc0d4b73d9689ed5e 292 Pfam PF13614 AAA domain 30 189 7.3E-20 T 29-03-2018 IPR025669 AAA domain CWR56_RS01355 0feb49587add3f9cc0d4b73d9689ed5e 292 PIRSF PIRSF003092 1 292 9.0E-88 T 29-03-2018 IPR025501 ATP binding protein MinD CWR56_RS01355 0feb49587add3f9cc0d4b73d9689ed5e 292 Gene3D G3DSA:3.40.50.300 28 272 2.9E-47 T 29-03-2018 CWR56_RS01355 0feb49587add3f9cc0d4b73d9689ed5e 292 SUPERFAMILY SSF52540 29 274 4.11E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 29-03-2018 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 Gene3D G3DSA:3.40.50.2300 169 336 9.8E-48 T 29-03-2018 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 SUPERFAMILY SSF47413 4 62 3.27E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 4.4E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 4.4E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 Gene3D G3DSA:3.40.50.2300 61 168 1.7E-28 T 29-03-2018 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 Pfam PF13377 Periplasmic binding protein-like domain 171 333 6.7E-38 T 29-03-2018 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 Gene3D G3DSA:1.10.10.10 2 19 0.016 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 SUPERFAMILY SSF53822 64 334 6.71E-79 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 SMART SM00354 4 74 3.3E-33 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 2.7E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR56_RS04910 80dcbdc61949a89ff51f13e85197d6c1 338 Gene3D G3DSA:1.10.260.40 20 60 6.3E-24 T 29-03-2018 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 SUPERFAMILY SSF54768 120 231 3.3E-24 T 29-03-2018 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 Gene3D G3DSA:3.30.160.20 165 233 4.2E-22 T 29-03-2018 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 SUPERFAMILY SSF69065 7 168 3.14E-50 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 Pfam PF14622 Ribonuclease-III-like 24 150 2.1E-43 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 15 231 1.7E-80 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 SMART SM00358 166 233 6.2E-20 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 Pfam PF00035 Double-stranded RNA binding motif 166 231 1.5E-17 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 SMART SM00535 26 159 1.2E-51 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 Gene3D G3DSA:1.10.1520.10 10 157 3.5E-47 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 Hamap MF_00104 Ribonuclease 3 [rnc]. 14 229 31.551 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CWR56_RS05765 f17bdbd7d336e820ed0922fd11a9834d 236 ProSitePatterns PS00517 Ribonuclease III family signature. 48 56 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS03120 38b966c075615df3e6277ada032e0970 126 SUPERFAMILY SSF46785 4 122 1.97E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03120 38b966c075615df3e6277ada032e0970 126 Gene3D G3DSA:1.10.10.10 7 71 1.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03120 38b966c075615df3e6277ada032e0970 126 Pfam PF03965 Penicillinase repressor 6 116 7.3E-13 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Pfam PF00773 RNB domain 247 576 3.8E-115 T 29-03-2018 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Pfam PF00575 S1 RNA binding domain 622 705 1.8E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SUPERFAMILY SSF50249 626 705 2.61E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Gene3D G3DSA:2.40.50.140 623 707 2.1E-19 T 29-03-2018 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SUPERFAMILY SSF50249 125 224 2.65E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SMART SM00316 624 706 1.7E-15 T 29-03-2018 IPR022967 RNA-binding domain, S1 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Gene3D G3DSA:2.40.50.140 123 214 0.0023 T 29-03-2018 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SMART SM00955 247 577 7.9E-177 T 29-03-2018 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 TIGRFAM TIGR02063 RNase_R: ribonuclease R 5 707 2.1E-262 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Gene3D G3DSA:2.40.50.140 71 122 0.19 T 29-03-2018 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SUPERFAMILY SSF50249 208 623 1.88E-145 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Pfam PF08206 Ribonuclease B OB domain 144 200 3.6E-11 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Pfam PF08206 Ribonuclease B OB domain 72 131 4.8E-16 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SMART SM00357 137 201 1.3E-6 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SMART SM00357 71 132 4.2E-6 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 Hamap MF_01895 Ribonuclease R [rnr]. 24 706 57.323 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 SUPERFAMILY SSF50249 53 134 2.57E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS15880 2a3edcc1c04867d37eb4f6a747eccc5a 711 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 61 706 3.8E-214 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CWR56_RS10285 1bee580d674a50fdc85ff64027e867e6 244 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 187 204 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CWR56_RS10285 1bee580d674a50fdc85ff64027e867e6 244 SUPERFAMILY SSF64005 10 237 1.7E-90 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS10285 1bee580d674a50fdc85ff64027e867e6 244 Pfam PF01255 Putative undecaprenyl diphosphate synthase 21 241 2.3E-84 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS10285 1bee580d674a50fdc85ff64027e867e6 244 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 14 241 1.0E-89 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS10285 1bee580d674a50fdc85ff64027e867e6 244 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 14 242 41.062 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS10285 1bee580d674a50fdc85ff64027e867e6 244 Gene3D G3DSA:3.40.1180.10 1 244 6.6E-93 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 Gene3D G3DSA:3.40.50.1970 7 173 3.0E-53 T 29-03-2018 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 PIRSF PIRSF001455 5 353 2.4E-106 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 345 7.7E-115 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 Pfam PF01761 3-dehydroquinate synthase 69 324 8.4E-95 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 Gene3D G3DSA:1.20.1090.10 175 353 9.4E-52 T 29-03-2018 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 SUPERFAMILY SSF56796 6 344 3.01E-100 T 29-03-2018 CWR56_RS08845 0008dca2f48787c82cb33eb9aa71d032 354 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 3 352 38.787 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR56_RS05955 189b354d2a1a1cd06947507c5876db24 141 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 139 26.054 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWR56_RS05955 189b354d2a1a1cd06947507c5876db24 141 SMART SM00732 4 104 2.3E-38 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWR56_RS05955 189b354d2a1a1cd06947507c5876db24 141 Gene3D G3DSA:3.30.420.140 2 141 3.9E-47 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWR56_RS05955 189b354d2a1a1cd06947507c5876db24 141 Pfam PF03652 Holliday junction resolvase 5 136 3.4E-45 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWR56_RS05955 189b354d2a1a1cd06947507c5876db24 141 SUPERFAMILY SSF53098 4 136 1.82E-42 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS05955 189b354d2a1a1cd06947507c5876db24 141 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 136 6.1E-48 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWR56_RS12100 802a98577c2f6618a04a6a131a4a8ae8 342 SMART SM00479 2 190 1.4E-5 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS12100 802a98577c2f6618a04a6a131a4a8ae8 342 Pfam PF00929 Exonuclease 4 177 9.2E-15 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS12100 802a98577c2f6618a04a6a131a4a8ae8 342 Gene3D G3DSA:3.30.420.10 2 184 1.9E-20 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS12100 802a98577c2f6618a04a6a131a4a8ae8 342 SUPERFAMILY SSF53098 4 180 4.76E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 Gene3D G3DSA:3.40.50.2300 47 246 0.0011 T 29-03-2018 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 13 551 1.7E-240 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 459 470 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 Pfam PF00920 Dehydratase family 30 548 1.1E-221 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 SUPERFAMILY SSF52016 371 550 7.69E-62 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 SUPERFAMILY SSF143975 4 370 4.58E-138 T 29-03-2018 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 118 128 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR56_RS09610 be03236f6c2b64763af3f9a1cdbc7811 551 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 551 46.192 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 3.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 3.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 190 203 3.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 3.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 Gene3D G3DSA:3.40.50.1000 92 228 7.1E-29 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 195 2.5E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 SUPERFAMILY SSF56784 4 228 3.31E-47 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 Gene3D G3DSA:1.10.150.240 17 91 2.8E-19 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 200 3.8E-27 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS08320 3c2eaa46bd5347de8123a08ce8e385c4 228 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 227 6.7E-67 T 29-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CWR56_RS14160 b861e8997ee5f22174dca8bcd9c82d01 623 Pfam PF04122 Putative cell wall binding repeat 2 326 413 3.6E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14160 b861e8997ee5f22174dca8bcd9c82d01 623 Pfam PF04122 Putative cell wall binding repeat 2 427 510 5.9E-12 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14160 b861e8997ee5f22174dca8bcd9c82d01 623 Pfam PF04122 Putative cell wall binding repeat 2 524 602 3.7E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS10440 f2086e733fa46e388d3dcc4dc6312cf4 376 SUPERFAMILY SSF47413 3 70 7.6E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS10440 f2086e733fa46e388d3dcc4dc6312cf4 376 SMART SM00530 10 65 0.0025 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10440 f2086e733fa46e388d3dcc4dc6312cf4 376 Gene3D G3DSA:1.10.260.40 4 136 3.1E-8 T 29-03-2018 CWR56_RS10440 f2086e733fa46e388d3dcc4dc6312cf4 376 Pfam PF12844 Helix-turn-helix domain 8 69 3.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07700 0ec3a7fde533db7144b0ad4f8a485ec8 416 SUPERFAMILY SSF103473 4 405 1.96E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS07700 0ec3a7fde533db7144b0ad4f8a485ec8 416 Pfam PF07690 Major Facilitator Superfamily 17 366 3.4E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS07700 0ec3a7fde533db7144b0ad4f8a485ec8 416 Gene3D G3DSA:1.20.1250.20 1 200 3.9E-29 T 29-03-2018 CWR56_RS07700 0ec3a7fde533db7144b0ad4f8a485ec8 416 Gene3D G3DSA:1.20.1250.20 206 412 1.7E-9 T 29-03-2018 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 7.8E-44 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.925 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 Pfam PF00203 Ribosomal protein S19 3 83 1.6E-35 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 PIRSF PIRSF002144 1 93 5.2E-33 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 Gene3D G3DSA:3.30.860.10 1 92 4.2E-39 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 SUPERFAMILY SSF54570 2 84 8.76E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.1E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.1E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00105 0b718bfd94c5746c07343afb642f8002 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.1E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 349 358 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 92 4.8E-6 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 SMART SM00382 161 342 7.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 Gene3D G3DSA:3.40.50.300 48 358 3.1E-84 T 29-03-2018 CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 10 438 7.4E-191 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 27 437 2.3E-201 T 29-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 SUPERFAMILY SSF52540 97 363 7.51E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01280 2c9db0884320f0d058c0b3b2eb7c4ea4 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 358 9.1E-77 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 PRINTS PR00944 Copper ion binding protein signature 28 41 2.8E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 PRINTS PR00944 Copper ion binding protein signature 2 14 2.8E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 PRINTS PR00944 Copper ion binding protein signature 53 66 2.8E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 Gene3D G3DSA:3.30.70.100 2 69 4.0E-15 T 29-03-2018 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 Pfam PF00403 Heavy-metal-associated domain 6 65 1.1E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS05130 adbb76e393fe08081d5b064a8c51a4c8 70 SUPERFAMILY SSF55008 1 66 6.41E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR56_RS17860 bbc8ddcd81dd3d7454e1db4d190f801a 417 Gene3D G3DSA:1.20.1250.20 207 413 2.9E-15 T 29-03-2018 CWR56_RS17860 bbc8ddcd81dd3d7454e1db4d190f801a 417 Gene3D G3DSA:1.20.1250.20 4 203 9.8E-24 T 29-03-2018 CWR56_RS17860 bbc8ddcd81dd3d7454e1db4d190f801a 417 SUPERFAMILY SSF103473 6 407 1.96E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS17860 bbc8ddcd81dd3d7454e1db4d190f801a 417 Pfam PF07690 Major Facilitator Superfamily 12 358 7.7E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS05190 b344964baca0e587b2c6c0d98ba1e9bf 235 Pfam PF04002 RadC-like JAB domain 114 232 1.9E-44 T 29-03-2018 IPR025657 RadC-like JAB domain CWR56_RS05190 b344964baca0e587b2c6c0d98ba1e9bf 235 Gene3D G3DSA:3.40.140.10 110 235 1.7E-46 T 29-03-2018 CWR56_RS05190 b344964baca0e587b2c6c0d98ba1e9bf 235 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 184 189 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CWR56_RS05190 b344964baca0e587b2c6c0d98ba1e9bf 235 Gene3D G3DSA:1.10.150.20 5 100 0.0014 T 29-03-2018 CWR56_RS05190 b344964baca0e587b2c6c0d98ba1e9bf 235 TIGRFAM TIGR00608 radc: DNA repair protein RadC 22 234 1.7E-69 T 29-03-2018 IPR001405 RadC protein CWR56_RS16100 e4767d3d5c93a1c0135bb11bc304c499 197 Gene3D G3DSA:3.40.109.10 1 197 8.6E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS16100 e4767d3d5c93a1c0135bb11bc304c499 197 SUPERFAMILY SSF55469 4 196 6.81E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS16100 e4767d3d5c93a1c0135bb11bc304c499 197 Pfam PF00881 Nitroreductase family 6 177 1.3E-37 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS05530 a8bf13631c91619875b4909e4a124913 159 Gene3D G3DSA:3.40.630.30 1 159 4.5E-21 T 29-03-2018 CWR56_RS05530 a8bf13631c91619875b4909e4a124913 159 Pfam PF00583 Acetyltransferase (GNAT) family 53 138 1.7E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS05530 a8bf13631c91619875b4909e4a124913 159 SUPERFAMILY SSF55729 5 156 8.14E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS08140 a189e5e8fc9fcb254fa3b0302b3ba337 433 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 5 424 3.3E-178 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CWR56_RS08140 a189e5e8fc9fcb254fa3b0302b3ba337 433 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 4 428 53.465 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CWR56_RS08140 a189e5e8fc9fcb254fa3b0302b3ba337 433 Pfam PF01964 Radical SAM ThiC family 5 422 4.5E-197 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CWR56_RS07820 671564204a56e1e1c5df54e662f09815 362 Pfam PF11202 Phosphoribosyl transferase (PRTase) 5 254 3.6E-106 T 29-03-2018 IPR011215 Phosphoribosyl transferase CWR56_RS07820 671564204a56e1e1c5df54e662f09815 362 PIRSF PIRSF020979 3 360 2.8E-83 T 29-03-2018 IPR011215 Phosphoribosyl transferase CWR56_RS07820 671564204a56e1e1c5df54e662f09815 362 Pfam PF15608 PELOTA RNA binding domain 281 358 1.0E-32 T 29-03-2018 IPR028157 PELOTA RNA-binding domain CWR56_RS05390 4c81563df9350d741eb096a9af641794 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 31 73 3.0E-12 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR56_RS05390 4c81563df9350d741eb096a9af641794 74 Hamap MF_01217 Acyl carrier protein [acpP]. 1 74 18.676 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR56_RS05390 4c81563df9350d741eb096a9af641794 74 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 74 2.0E-28 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR56_RS05390 4c81563df9350d741eb096a9af641794 74 Pfam PF00550 Phosphopantetheine attachment site 4 70 9.6E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR56_RS05390 4c81563df9350d741eb096a9af641794 74 SUPERFAMILY SSF47336 2 73 2.09E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR56_RS05390 4c81563df9350d741eb096a9af641794 74 Gene3D G3DSA:1.10.1200.10 1 74 9.2E-27 T 29-03-2018 CWR56_RS09535 8ca0971a8dc476ec0c440a251f79f772 213 Pfam PF07853 Protein of unknown function (DUF1648) 14 62 1.5E-17 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CWR56_RS09535 8ca0971a8dc476ec0c440a251f79f772 213 PIRSF PIRSF038959 1 213 3.2E-37 T 29-03-2018 IPR026272 Immunity protein SdpI CWR56_RS09535 8ca0971a8dc476ec0c440a251f79f772 213 Pfam PF13630 SdpI/YhfL protein family 136 202 3.7E-20 T 29-03-2018 IPR025962 SdpI/YhfL protein family CWR56_RS09400 f856becfbff61e615c6af64c837a33eb 426 Gene3D G3DSA:3.40.640.10 66 278 5.6E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS09400 f856becfbff61e615c6af64c837a33eb 426 Pfam PF06838 Methionine gamma-lyase 21 419 4.8E-186 T 29-03-2018 IPR009651 Putative methionine gamma-lyase CWR56_RS09400 f856becfbff61e615c6af64c837a33eb 426 SUPERFAMILY SSF53383 50 375 6.05E-45 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS15050 785131a8d209f423c02d0cd5156c485f 155 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 25 144 1.2E-22 T 29-03-2018 IPR010181 CGCAxxGCC motif CWR56_RS15050 785131a8d209f423c02d0cd5156c485f 155 SUPERFAMILY SSF48695 15 146 3.72E-5 T 29-03-2018 IPR011031 Multihaem cytochrome CWR56_RS15050 785131a8d209f423c02d0cd5156c485f 155 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 25 144 2.4E-25 T 29-03-2018 IPR010181 CGCAxxGCC motif CWR56_RS04225 85620f152dc77490230f0eceb5eabee3 209 Pfam PF12002 MgsA AAA+ ATPase C terminal 63 151 2.1E-6 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CWR56_RS04225 85620f152dc77490230f0eceb5eabee3 209 SUPERFAMILY SSF48019 23 202 1.93E-32 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR56_RS04225 85620f152dc77490230f0eceb5eabee3 209 Gene3D G3DSA:1.20.272.10 23 120 9.6E-26 T 29-03-2018 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 Gene3D G3DSA:3.30.565.10 269 424 2.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 5.0E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 5.0E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 5.0E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 SUPERFAMILY SSF47384 183 260 1.61E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 Gene3D G3DSA:1.10.287.130 185 258 4.7E-13 T 29-03-2018 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 Pfam PF00512 His Kinase A (phospho-acceptor) domain 197 260 1.2E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 SUPERFAMILY SSF55874 266 423 4.58E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 420 9.9E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 SMART SM00387 307 425 6.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS10150 78a28e3176e13b58662ddda8fedc0e11 425 SMART SM00388 196 262 1.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS00715 314cb4d8b725fc1e4306aa23a13f84ab 150 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 6 135 4.5E-41 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CWR56_RS00715 314cb4d8b725fc1e4306aa23a13f84ab 150 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 131 4.4E-40 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CWR56_RS00715 314cb4d8b725fc1e4306aa23a13f84ab 150 Gene3D G3DSA:3.40.50.300 1 150 9.6E-50 T 29-03-2018 CWR56_RS00715 314cb4d8b725fc1e4306aa23a13f84ab 150 SUPERFAMILY SSF52540 23 148 1.38E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06550 6095a342d7ec3f1a2ba7ed2181734608 211 Pfam PF00857 Isochorismatase family 31 157 2.4E-15 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWR56_RS06550 6095a342d7ec3f1a2ba7ed2181734608 211 Gene3D G3DSA:3.40.50.850 30 209 2.6E-25 T 29-03-2018 CWR56_RS06550 6095a342d7ec3f1a2ba7ed2181734608 211 SUPERFAMILY SSF52499 23 183 4.45E-21 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWR56_RS09015 c4a03d13b44f94e5d9a3de955fbb786d 169 Pfam PF04645 Protein of unknown function, DUF603 14 94 5.0E-5 T 29-03-2018 IPR006739 Protein of unknown function DUF603 CWR56_RS09015 c4a03d13b44f94e5d9a3de955fbb786d 169 Gene3D G3DSA:1.10.3100.10 1 100 1.1E-22 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS09015 c4a03d13b44f94e5d9a3de955fbb786d 169 Pfam PF01381 Helix-turn-helix 6 58 1.0E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09015 c4a03d13b44f94e5d9a3de955fbb786d 169 SUPERFAMILY SSF47413 2 65 9.12E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS09015 c4a03d13b44f94e5d9a3de955fbb786d 169 SMART SM00530 5 60 7.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS04155 7a8b6ad3be2c931a4ddcf818b9da7163 117 Gene3D G3DSA:3.40.1440.10 16 116 4.6E-15 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS04155 7a8b6ad3be2c931a4ddcf818b9da7163 117 SUPERFAMILY SSF82771 19 107 9.81E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR56_RS14170 e690c83e97d2a14789c6671182c8c7ee 732 Pfam PF12211 Low molecular weight S layer protein N terminal 31 290 1.4E-20 T 29-03-2018 IPR021071 Low molecular weight S layer protein, N-terminal CWR56_RS14170 e690c83e97d2a14789c6671182c8c7ee 732 Pfam PF04122 Putative cell wall binding repeat 2 511 599 3.7E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14170 e690c83e97d2a14789c6671182c8c7ee 732 Pfam PF04122 Putative cell wall binding repeat 2 393 499 6.9E-12 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14170 e690c83e97d2a14789c6671182c8c7ee 732 Pfam PF04122 Putative cell wall binding repeat 2 613 693 2.9E-7 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 SMART SM00387 223 334 9.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 260 274 1.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 288 1.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 331 1.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 312 1.6E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 SUPERFAMILY SSF55874 169 331 2.23E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 331 4.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS07245 fbdb9429ab24b2b9333c84e311945e1d 334 Gene3D G3DSA:3.30.565.10 141 330 5.1E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS04185 a41d2a839d2d21d826515537e90f1843 132 Pfam PF03188 Eukaryotic cytochrome b561 9 100 3.0E-6 T 29-03-2018 IPR006593 Cytochrome b561/ferric reductase transmembrane CWR56_RS04185 a41d2a839d2d21d826515537e90f1843 132 TIGRFAM TIGR03987 TIGR03987: TIGR03987 family protein 5 130 1.8E-56 T 29-03-2018 IPR023813 Conserved hypothetical protein CHP03987 CWR56_RS16630 9494f5015195b44408b0219f509c890d 156 Gene3D G3DSA:3.60.21.10 1 156 3.5E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS16630 9494f5015195b44408b0219f509c890d 156 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 149 1.3E-34 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CWR56_RS16630 9494f5015195b44408b0219f509c890d 156 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 147 4.3E-31 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CWR56_RS16630 9494f5015195b44408b0219f509c890d 156 SUPERFAMILY SSF56300 1 155 5.29E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS04100 642c65f385ff90751fcdc4886c6e4997 173 Pfam PF00881 Nitroreductase family 63 150 3.9E-13 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS04100 642c65f385ff90751fcdc4886c6e4997 173 Pfam PF00881 Nitroreductase family 5 56 3.5E-15 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS04100 642c65f385ff90751fcdc4886c6e4997 173 Gene3D G3DSA:3.40.109.10 2 164 4.2E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS04100 642c65f385ff90751fcdc4886c6e4997 173 SUPERFAMILY SSF55469 2 164 5.5E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS06570 a414b9952e794b8f39fe921f16ad1df8 115 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 55 102 8.2E-9 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D CWR56_RS18045 5c0ed8e21d8f5b4181380076e0e109fb 150 Pfam PF12638 Staygreen protein 4 148 2.7E-36 T 29-03-2018 IPR024438 Staygreen protein CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 22 110 6.8E-27 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 Pfam PF02650 WhiA C-terminal HTH domain 228 311 2.8E-38 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 7 311 4.1E-102 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 SUPERFAMILY SSF55608 131 229 4.08E-19 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 Gene3D G3DSA:3.10.28.10 15 107 4.6E-13 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 6 314 34.852 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 Gene3D G3DSA:3.10.28.10 132 211 1.6E-20 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CWR56_RS16910 4371b7e5dff91234c745f358e8adb356 318 Pfam PF14527 WhiA LAGLIDADG-like domain 134 225 2.1E-33 T 29-03-2018 CWR56_RS06200 cd137df58bb3aae16eafc45fe43d90c6 274 Pfam PF02673 Bacitracin resistance protein BacA 12 266 1.2E-90 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR56_RS06200 cd137df58bb3aae16eafc45fe43d90c6 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 7 271 18.692 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR56_RS06200 cd137df58bb3aae16eafc45fe43d90c6 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 12 264 1.5E-78 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 SUPERFAMILY SSF82114 172 302 4.36E-41 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 Gene3D G3DSA:2.40.30.30 178 304 6.1E-36 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 PIRSF PIRSF004491 1 308 3.7E-106 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 Pfam PF01687 Riboflavin kinase 182 299 1.5E-33 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 17 298 2.9E-84 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 Gene3D G3DSA:3.40.50.620 1 177 1.6E-48 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 SUPERFAMILY SSF52374 16 181 1.72E-33 T 29-03-2018 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 Pfam PF06574 FAD synthetase 12 164 2.4E-49 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWR56_RS06105 0de588f57fa72706d4286eb99bf553e9 309 SMART SM00904 181 305 7.5E-51 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR56_RS03010 6a24604868086acf0ebbff4d58eb0d20 365 Gene3D G3DSA:1.10.10.60 308 364 1.0E-10 T 29-03-2018 CWR56_RS03010 6a24604868086acf0ebbff4d58eb0d20 365 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 80 361 2.6E-26 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CWR56_RS03010 6a24604868086acf0ebbff4d58eb0d20 365 Pfam PF12784 PD-(D/E)XK nuclease family transposase 79 290 6.6E-30 T 29-03-2018 CWR56_RS05270 6ed369b1fab4032f40479669c4a953ee 473 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 402 4.3E-120 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CWR56_RS05270 6ed369b1fab4032f40479669c4a953ee 473 Pfam PF10150 Ribonuclease E/G family 102 369 1.0E-96 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CWR56_RS05270 6ed369b1fab4032f40479669c4a953ee 473 Gene3D G3DSA:2.40.50.140 31 105 4.2E-14 T 29-03-2018 CWR56_RS05270 6ed369b1fab4032f40479669c4a953ee 473 SUPERFAMILY SSF50249 39 105 2.14E-9 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 56 67 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 7 291 1.5E-97 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 Gene3D G3DSA:3.30.70.20 65 85 1.1E-7 T 29-03-2018 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 SUPERFAMILY SSF54862 24 104 8.38E-12 T 29-03-2018 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 Pfam PF04055 Radical SAM superfamily 25 234 1.8E-23 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 Pfam PF13353 4Fe-4S single cluster domain 17 189 4.8E-11 T 29-03-2018 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 PIRSF PIRSF000371 1 299 2.8E-90 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 Gene3D G3DSA:3.80.30.10 123 297 2.3E-37 T 29-03-2018 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 Gene3D G3DSA:3.30.70.20 86 122 0.012 T 29-03-2018 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 Gene3D G3DSA:1.10.1060.10 28 64 0.0066 T 29-03-2018 CWR56_RS05060 f73f99b169982dc116dda05e0a2c5546 300 SUPERFAMILY SSF102114 82 285 2.39E-21 T 29-03-2018 CWR56_RS12570 561558698a150a6d31f860d13405a345 105 Gene3D G3DSA:3.40.50.2300 4 102 5.0E-37 T 29-03-2018 CWR56_RS12570 561558698a150a6d31f860d13405a345 105 SUPERFAMILY SSF52794 4 102 5.58E-33 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12570 561558698a150a6d31f860d13405a345 105 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 6 90 6.5E-29 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS12570 561558698a150a6d31f860d13405a345 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 7 98 6.7E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 Gene3D G3DSA:3.10.290.10 1 59 5.5E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 231 4.1E-47 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 SUPERFAMILY SSF55174 6 63 2.16E-12 T 29-03-2018 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 Pfam PF00849 RNA pseudouridylate synthase 66 198 1.6E-19 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 SUPERFAMILY SSF55120 49 236 2.34E-45 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 Gene3D G3DSA:3.30.70.1560 147 216 4.5E-24 T 29-03-2018 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 Gene3D G3DSA:3.30.70.580 60 146 8.2E-19 T 29-03-2018 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 SMART SM00363 5 65 4.1E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS01935 2f04c10acdeb22dc76be7d5b7906326a 240 Pfam PF01479 S4 domain 5 52 3.1E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR56_RS12450 696733712963ee447b018ddb507c1457 339 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 338 1.4E-91 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWR56_RS12450 696733712963ee447b018ddb507c1457 339 PIRSF PIRSF005485 1 339 7.0E-97 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWR56_RS12450 696733712963ee447b018ddb507c1457 339 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 333 27.879 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWR56_RS12450 696733712963ee447b018ddb507c1457 339 SUPERFAMILY SSF55781 72 338 9.81E-48 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS12450 696733712963ee447b018ddb507c1457 339 Pfam PF01628 HrcA protein C terminal domain 106 325 2.6E-54 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CWR56_RS12450 696733712963ee447b018ddb507c1457 339 Gene3D G3DSA:3.30.450.40 187 339 5.4E-34 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS12450 696733712963ee447b018ddb507c1457 339 SUPERFAMILY SSF46785 2 85 3.63E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12450 696733712963ee447b018ddb507c1457 339 Gene3D G3DSA:1.10.10.10 1 86 7.8E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14115 49dbf11d5e7e7689cf97cada2a911819 228 Pfam PF02397 Bacterial sugar transferase 44 222 9.4E-67 T 29-03-2018 IPR003362 Bacterial sugar transferase CWR56_RS00270 844afaa174e3a31d97258874258fb0f2 234 SMART SM00646 118 230 4.1E-32 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS00270 844afaa174e3a31d97258874258fb0f2 234 SUPERFAMILY SSF53187 41 233 2.72E-52 T 29-03-2018 CWR56_RS00270 844afaa174e3a31d97258874258fb0f2 234 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 41 232 1.7E-71 T 29-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD CWR56_RS00270 844afaa174e3a31d97258874258fb0f2 234 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 43 230 1.8E-51 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS00270 844afaa174e3a31d97258874258fb0f2 234 Gene3D G3DSA:3.40.630.40 38 234 4.8E-55 T 29-03-2018 CWR56_RS14740 4527829ddfed9f9c93946113107ff936 469 SUPERFAMILY SSF143985 220 343 6.93E-39 T 29-03-2018 CWR56_RS14740 4527829ddfed9f9c93946113107ff936 469 SUPERFAMILY SSF141523 347 468 7.98E-32 T 29-03-2018 CWR56_RS14740 4527829ddfed9f9c93946113107ff936 469 Pfam PF12229 Putative peptidoglycan binding domain 216 329 4.5E-16 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CWR56_RS14740 4527829ddfed9f9c93946113107ff936 469 Pfam PF12229 Putative peptidoglycan binding domain 85 199 8.2E-9 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CWR56_RS14740 4527829ddfed9f9c93946113107ff936 469 Gene3D G3DSA:2.40.440.10 342 469 1.8E-26 T 29-03-2018 CWR56_RS14740 4527829ddfed9f9c93946113107ff936 469 Pfam PF03734 L,D-transpeptidase catalytic domain 350 467 2.5E-18 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CWR56_RS05140 d4a9a1e7eee74da1259d1749fdda9c4e 123 Gene3D G3DSA:3.10.180.10 2 123 5.9E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS05140 d4a9a1e7eee74da1259d1749fdda9c4e 123 SUPERFAMILY SSF54593 3 119 2.95E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS05140 d4a9a1e7eee74da1259d1749fdda9c4e 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 118 4.4E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SMART SM00052 710 956 1.0E-96 T 29-03-2018 IPR001633 EAL domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SUPERFAMILY SSF141868 715 961 5.89E-84 T 29-03-2018 IPR001633 EAL domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 539 696 7.0E-16 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SUPERFAMILY SSF55073 562 702 1.57E-22 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SUPERFAMILY SSF53850 269 491 3.36E-26 T 29-03-2018 CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Gene3D G3DSA:3.30.70.270 536 706 7.0E-29 T 29-03-2018 CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 277 484 4.1E-22 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 254 9.9E-25 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SMART SM00062 276 496 1.2E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SMART SM00062 37 256 4.1E-12 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Gene3D G3DSA:3.40.190.10 265 416 4.7E-17 T 29-03-2018 CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Gene3D G3DSA:3.20.20.450 707 960 2.0E-93 T 29-03-2018 IPR001633 EAL domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Pfam PF00990 Diguanylate cyclase, GGDEF domain 542 695 1.9E-20 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Gene3D G3DSA:3.40.190.10 29 133 2.4E-15 T 29-03-2018 CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SMART SM00267 531 700 1.7E-11 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Pfam PF00563 EAL domain 717 951 1.1E-69 T 29-03-2018 IPR001633 EAL domain CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 SUPERFAMILY SSF53850 38 256 6.04E-33 T 29-03-2018 CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Gene3D G3DSA:3.40.190.10 417 499 0.094 T 29-03-2018 CWR56_RS06950 696c1ae7444b0eadcbe0d9cffff5a3a0 965 Gene3D G3DSA:3.40.190.10 134 260 9.1E-14 T 29-03-2018 CWR56_RS15810 1f53f91b950d46e185595208e2340f28 163 SUPERFAMILY SSF47413 1 71 2.95E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS15810 1f53f91b950d46e185595208e2340f28 163 Gene3D G3DSA:1.10.3100.10 1 163 1.9E-20 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS15810 1f53f91b950d46e185595208e2340f28 163 SMART SM00530 9 64 1.2E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15810 1f53f91b950d46e185595208e2340f28 163 Pfam PF01381 Helix-turn-helix 10 60 3.1E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 Gene3D G3DSA:3.30.830.10 220 411 1.1E-35 T 29-03-2018 CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 SUPERFAMILY SSF63411 3 209 2.67E-57 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 SUPERFAMILY SSF63411 230 410 2.23E-35 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 Gene3D G3DSA:3.30.830.10 1 216 6.9E-58 T 29-03-2018 CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 Pfam PF00675 Insulinase (Peptidase family M16) 16 159 1.5E-38 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CWR56_RS06135 d7c0e2b4220769eebd0060d98afac394 415 Pfam PF05193 Peptidase M16 inactive domain 165 340 3.1E-38 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CWR56_RS17175 ce81ba2969af36ff382ba790c49ddfc3 101 PIRSF PIRSF000699 1 101 1.3E-26 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS17175 ce81ba2969af36ff382ba790c49ddfc3 101 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 98 4.5E-30 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS17175 ce81ba2969af36ff382ba790c49ddfc3 101 Gene3D G3DSA:1.20.58.80 1 101 2.4E-31 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS17175 ce81ba2969af36ff382ba790c49ddfc3 101 SUPERFAMILY SSF46973 2 99 3.53E-28 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS17985 c9c497ace6e969ed5118c7b9580eb93f 238 SUPERFAMILY SSF55166 83 225 1.81E-31 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS17985 c9c497ace6e969ed5118c7b9580eb93f 238 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 95 218 1.4E-36 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CWR56_RS17985 c9c497ace6e969ed5118c7b9580eb93f 238 Gene3D G3DSA:3.30.1380.10 55 229 1.7E-32 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS12550 f9c31e744f2fd65228f8304a9bfcfb5b 352 Gene3D G3DSA:3.10.520.10 21 337 6.8E-56 T 29-03-2018 CWR56_RS12550 f9c31e744f2fd65228f8304a9bfcfb5b 352 SUPERFAMILY SSF143631 32 337 4.45E-97 T 29-03-2018 IPR003374 ApbE-like domain CWR56_RS12550 f9c31e744f2fd65228f8304a9bfcfb5b 352 Pfam PF02424 ApbE family 40 320 4.6E-84 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CWR56_RS12550 f9c31e744f2fd65228f8304a9bfcfb5b 352 PIRSF PIRSF006268 1 342 5.0E-113 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CWR56_RS17705 9820f60fee7444db8e4551c739d1a48d 469 SUPERFAMILY SSF53383 3 367 3.06E-71 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS17705 9820f60fee7444db8e4551c739d1a48d 469 SUPERFAMILY SSF55904 325 465 1.44E-31 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR56_RS17705 9820f60fee7444db8e4551c739d1a48d 469 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 5 297 7.4E-60 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CWR56_RS17705 9820f60fee7444db8e4551c739d1a48d 469 Gene3D G3DSA:3.40.640.10 2 279 2.8E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS17705 9820f60fee7444db8e4551c739d1a48d 469 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 370 446 8.3E-11 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR56_RS17705 9820f60fee7444db8e4551c739d1a48d 469 Gene3D G3DSA:3.90.100.10 355 469 4.3E-26 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR56_RS04105 a5a86974e66accc5ec8ae3264c4ab7f0 103 SUPERFAMILY SSF48295 69 101 7.32E-5 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CWR56_RS04105 a5a86974e66accc5ec8ae3264c4ab7f0 103 Gene3D G3DSA:1.10.10.60 58 101 2.1E-9 T 29-03-2018 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 Pfam PF01430 Hsp33 protein 3 279 1.1E-88 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 PIRSF PIRSF005261 1 291 2.2E-80 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 SUPERFAMILY SSF118352 233 290 3.14E-17 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 37.096 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 Gene3D G3DSA:3.55.30.10 2 234 1.9E-73 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 Gene3D G3DSA:3.90.1280.10 235 288 1.4E-19 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CWR56_RS16170 f5b836ed96665d3eba67f6acf9122fe6 291 SUPERFAMILY SSF64397 2 241 6.02E-72 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 Pfam PF01039 Carboxyl transferase domain 65 243 6.4E-25 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 284 38.785 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 203 220 1.2E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 166 184 1.2E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 132 146 1.2E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 254 263 1.2E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 232 243 1.2E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 22 283 1.4E-115 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 SUPERFAMILY SSF52096 31 282 1.39E-82 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS09215 66790f98696fa9bb28cd100f83947425 284 Gene3D G3DSA:3.90.226.10 18 284 1.2E-73 T 29-03-2018 CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 SUPERFAMILY SSF53187 310 391 3.67E-54 T 29-03-2018 CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 SUPERFAMILY SSF53187 4 175 3.67E-54 T 29-03-2018 CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 Gene3D G3DSA:3.40.630.10 2 266 1.5E-61 T 29-03-2018 CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 Pfam PF07687 Peptidase dimerisation domain 172 279 8.3E-16 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 SUPERFAMILY SSF55031 180 277 1.31E-16 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 Pfam PF01546 Peptidase family M20/M25/M40 68 390 7.3E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 Gene3D G3DSA:3.40.630.10 267 394 1.7E-4 T 29-03-2018 CWR56_RS10000 3a349ba6c3d1d3af04d78c00d15fad01 395 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR56_RS14090 99dfb77181f4adcb2c89db73b9656c14 240 SUPERFAMILY SSF53448 2 222 1.8E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14090 99dfb77181f4adcb2c89db73b9656c14 240 Gene3D G3DSA:3.90.550.10 12 236 5.5E-7 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14090 99dfb77181f4adcb2c89db73b9656c14 240 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 20 102 2.2E-15 T 29-03-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif CWR56_RS14090 99dfb77181f4adcb2c89db73b9656c14 240 Pfam PF04572 Alpha 1,4-glycosyltransferase conserved region 122 233 8.0E-5 T 29-03-2018 IPR007652 Alpha 1,4-glycosyltransferase domain CWR56_RS14825 b394aa15a570ba209c9312b980dceb54 304 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 10 300 4.7E-62 T 29-03-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap CWR56_RS14825 b394aa15a570ba209c9312b980dceb54 304 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 8 223 5.4E-43 T 29-03-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CWR56_RS14825 b394aa15a570ba209c9312b980dceb54 304 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 221 4.6E-32 T 29-03-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Gene3D G3DSA:2.60.40.740 605 735 1.3E-4 T 29-03-2018 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Gene3D G3DSA:2.60.40.740 317 445 4.9E-18 T 29-03-2018 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Gene3D G3DSA:2.60.40.740 450 602 1.4E-11 T 29-03-2018 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Pfam PF05737 Collagen binding domain 467 592 7.4E-5 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Pfam PF05737 Collagen binding domain 334 431 7.4E-8 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 SUPERFAMILY SSF49401 185 298 1.99E-6 T 29-03-2018 IPR008966 Adhesion domain CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 SUPERFAMILY SSF49401 333 444 9.94E-15 T 29-03-2018 IPR008966 Adhesion domain CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Gene3D G3DSA:2.60.40.10 736 832 1.8E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 SUPERFAMILY SSF49401 465 596 5.47E-5 T 29-03-2018 IPR008966 Adhesion domain CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 Gene3D G3DSA:2.60.40.1280 171 301 2.2E-5 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 462 498 1.6E-4 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS14370 7c7355a22681f29ad86e89c2aaf8a232 972 SUPERFAMILY SSF49478 742 809 1.77E-5 T 29-03-2018 CWR56_RS15865 ef84f071d2514af7afd568abca557603 429 Pfam PF12698 ABC-2 family transporter protein 18 396 3.9E-30 T 29-03-2018 CWR56_RS05915 8a1d87df92c4da9f9b39825ccdd374e6 256 Gene3D G3DSA:3.40.630.30 117 255 2.2E-13 T 29-03-2018 CWR56_RS05915 8a1d87df92c4da9f9b39825ccdd374e6 256 Pfam PF12746 GNAT acetyltransferase 124 254 1.8E-24 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like CWR56_RS05915 8a1d87df92c4da9f9b39825ccdd374e6 256 SUPERFAMILY SSF55729 154 254 1.6E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS07515 90ec6c58520219f9faa3aa17dd37eb12 316 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 7 287 7.8E-38 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR56_RS07515 90ec6c58520219f9faa3aa17dd37eb12 316 SUPERFAMILY SSF53067 2 111 3.24E-21 T 29-03-2018 CWR56_RS07515 90ec6c58520219f9faa3aa17dd37eb12 316 SUPERFAMILY SSF53067 116 312 5.18E-41 T 29-03-2018 CWR56_RS07515 90ec6c58520219f9faa3aa17dd37eb12 316 Gene3D G3DSA:3.30.420.40 129 281 7.2E-33 T 29-03-2018 CWR56_RS07515 90ec6c58520219f9faa3aa17dd37eb12 316 Gene3D G3DSA:3.30.420.40 1 128 1.2E-17 T 29-03-2018 CWR56_RS10660 2c2a59a6b28477d7f6a009f788244764 174 SUPERFAMILY SSF52218 1 141 7.78E-21 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS10660 2c2a59a6b28477d7f6a009f788244764 174 Pfam PF12724 Flavodoxin domain 6 134 3.1E-18 T 29-03-2018 IPR026816 Flavodoxin domain CWR56_RS10660 2c2a59a6b28477d7f6a009f788244764 174 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CWR56_RS10660 2c2a59a6b28477d7f6a009f788244764 174 Gene3D G3DSA:3.40.50.360 1 155 4.1E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 PRINTS PR00107 Phosphocarrier protein signature 12 28 1.3E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 PRINTS PR00107 Phosphocarrier protein signature 52 69 1.3E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 PRINTS PR00107 Phosphocarrier protein signature 37 52 1.3E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 Pfam PF00381 PTS HPr component phosphorylation site 2 81 3.3E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 SUPERFAMILY SSF55594 2 86 5.1E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 81 4.8E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS13980 3e7bfd2a9d377b3aaebc67808511366c 86 Gene3D G3DSA:3.30.1340.10 1 86 2.2E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 SUPERFAMILY SSF51338 306 366 5.4E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 Gene3D G3DSA:2.30.40.10 1 69 2.8E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 Pfam PF01979 Amidohydrolase family 52 365 1.0E-17 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 SUPERFAMILY SSF51338 3 64 9.03E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 Gene3D G3DSA:3.20.20.140 70 318 6.0E-40 T 29-03-2018 CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 3 367 3.3E-177 T 29-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 PIRSF PIRSF039004 1 377 5.8E-141 T 29-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CWR56_RS18200 5fef4c2b061de985148664a88bd027c4 377 SUPERFAMILY SSF51556 56 319 7.38E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS01430 6c92da8e6fa9b5edd364b849d62049bf 131 SUPERFAMILY SSF50475 2 124 1.25E-22 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS01430 6c92da8e6fa9b5edd364b849d62049bf 131 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 2 84 3.4E-13 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CWR56_RS01430 6c92da8e6fa9b5edd364b849d62049bf 131 Gene3D G3DSA:2.30.110.10 2 131 1.4E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS08195 1fa0db337d89b7586feda0242fba9bbc 167 SMART SM00852 5 150 3.4E-28 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS08195 1fa0db337d89b7586feda0242fba9bbc 167 Gene3D G3DSA:3.40.980.10 1 161 2.1E-39 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS08195 1fa0db337d89b7586feda0242fba9bbc 167 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 66 79 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CWR56_RS08195 1fa0db337d89b7586feda0242fba9bbc 167 Pfam PF00994 Probable molybdopterin binding domain 5 149 4.0E-34 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS08195 1fa0db337d89b7586feda0242fba9bbc 167 SUPERFAMILY SSF53218 2 155 6.02E-42 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS08195 1fa0db337d89b7586feda0242fba9bbc 167 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 144 3.6E-36 T 29-03-2018 IPR001453 MoaB/Mog domain CWR56_RS02000 14bb7296ef821a1b605dc0c2a9b908b7 71 Gene3D G3DSA:1.10.443.10 22 67 4.7E-9 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS02000 14bb7296ef821a1b605dc0c2a9b908b7 71 Pfam PF00589 Phage integrase family 23 56 3.6E-6 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS02000 14bb7296ef821a1b605dc0c2a9b908b7 71 SUPERFAMILY SSF56349 23 66 6.18E-11 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS12750 3fa179fce248732bf2e3cbf4f41a70c7 116 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.272 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CWR56_RS12750 3fa179fce248732bf2e3cbf4f41a70c7 116 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 3.7E-27 T 29-03-2018 CWR56_RS12750 3fa179fce248732bf2e3cbf4f41a70c7 116 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 3.6E-36 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CWR56_RS12750 3fa179fce248732bf2e3cbf4f41a70c7 116 Gene3D G3DSA:3.30.460.10 1 108 2.6E-33 T 29-03-2018 CWR56_RS12750 3fa179fce248732bf2e3cbf4f41a70c7 116 SUPERFAMILY SSF81301 1 114 7.36E-40 T 29-03-2018 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 Gene3D G3DSA:3.40.50.1400 125 236 4.1E-26 T 29-03-2018 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 SUPERFAMILY SSF53800 2 256 2.09E-84 T 29-03-2018 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 Gene3D G3DSA:3.40.50.1400 1 124 5.0E-10 T 29-03-2018 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 SUPERFAMILY SSF53790 260 487 1.45E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 264 278 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 Gene3D G3DSA:3.40.1010.10 259 403 5.2E-24 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 260 470 2.6E-44 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 260 487 2.5E-72 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CWR56_RS17050 4dc6b52c31d6dd3db7826bc88094b332 492 Pfam PF06180 Cobalt chelatase (CbiK) 3 254 5.5E-98 T 29-03-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 Pfam PF13534 4Fe-4S dicluster domain 290 358 3.9E-10 T 29-03-2018 CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 290 301 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 Gene3D G3DSA:3.20.20.100 1 284 9.4E-47 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 SUPERFAMILY SSF46548 286 366 3.4E-13 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 Gene3D G3DSA:3.30.70.20 287 344 1.3E-7 T 29-03-2018 CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 344 355 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 Pfam PF00248 Aldo/keto reductase family 5 279 1.2E-58 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 SUPERFAMILY SSF51430 4 281 8.38E-49 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR56_RS16025 7f73903e41d96617f777c797e6b60e9c 373 Gene3D G3DSA:3.30.70.20 345 370 0.012 T 29-03-2018 CWR56_RS05455 f532f0fd9030a0c4b2ab97fd3bbcb256 403 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 78 397 5.4E-84 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CWR56_RS05455 f532f0fd9030a0c4b2ab97fd3bbcb256 403 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 17 396 1.7E-77 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CWR56_RS13900 7bee112e8a0e184f782fe31111bef3f5 519 SUPERFAMILY SSF102114 184 505 1.05E-75 T 29-03-2018 CWR56_RS13900 7bee112e8a0e184f782fe31111bef3f5 519 Gene3D G3DSA:3.20.20.70 141 518 3.4E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13900 7bee112e8a0e184f782fe31111bef3f5 519 SMART SM00729 193 411 1.7E-40 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS13900 7bee112e8a0e184f782fe31111bef3f5 519 Pfam PF04055 Radical SAM superfamily 198 373 3.3E-20 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS13900 7bee112e8a0e184f782fe31111bef3f5 519 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 111 512 1.8E-174 T 29-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ CWR56_RS06235 95c6e483d2279e366523ec74b71d9ee5 258 Pfam PF00929 Exonuclease 5 179 9.3E-14 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS06235 95c6e483d2279e366523ec74b71d9ee5 258 Gene3D G3DSA:3.30.420.10 1 193 9.5E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS06235 95c6e483d2279e366523ec74b71d9ee5 258 SMART SM00479 2 188 1.5E-6 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR56_RS06235 95c6e483d2279e366523ec74b71d9ee5 258 SUPERFAMILY SSF53098 1 241 1.01E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS12880 2a842d5484e937698495bb141e730bea 269 Gene3D G3DSA:1.10.3720.10 1 256 1.6E-44 T 29-03-2018 CWR56_RS12880 2a842d5484e937698495bb141e730bea 269 SUPERFAMILY SSF161098 4 269 5.1E-69 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS12880 2a842d5484e937698495bb141e730bea 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 256 9.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 349 6.4E-145 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 Gene3D G3DSA:3.40.50.880 141 349 8.8E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00097 Anthranilate synthase component II signature 323 336 3.8E-7 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00097 Anthranilate synthase component II signature 213 222 3.8E-7 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00097 Anthranilate synthase component II signature 240 251 3.8E-7 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 SMART SM01097 1 131 1.7E-86 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 2.0E-52 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 SUPERFAMILY SSF52021 1 146 4.32E-56 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 Pfam PF00117 Glutamine amidotransferase class-I 173 346 1.3E-47 T 29-03-2018 IPR017926 Glutamine amidotransferase CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 349 47.252 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 SUPERFAMILY SSF52317 149 348 8.35E-61 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 Gene3D G3DSA:3.50.30.20 1 140 2.0E-59 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 1.7E-36 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 1.7E-36 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 1.7E-36 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 1.7E-36 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 1.7E-36 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00096 Glutamine amidotransferase superfamily signature 323 336 2.9E-12 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 2.9E-12 T 29-03-2018 CWR56_RS17925 5ab850cccd27f3a3240c1b70aee9cc3d 349 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 2.9E-12 T 29-03-2018 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 Gene3D G3DSA:1.10.1790.10 164 279 4.9E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 Pfam PF00874 PRD domain 75 161 2.6E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 Pfam PF00874 PRD domain 181 274 3.9E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 SUPERFAMILY SSF63520 56 165 1.31E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 Gene3D G3DSA:2.30.24.10 1 63 5.0E-18 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 SUPERFAMILY SSF63520 175 275 1.57E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 SUPERFAMILY SSF50151 1 53 1.96E-14 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 Gene3D G3DSA:1.10.1790.10 64 163 4.0E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 Pfam PF03123 CAT RNA binding domain 1 53 4.9E-17 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS15570 894abbf8e034decf060670a05d522211 286 SMART SM01061 1 58 1.5E-22 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR56_RS08965 aec97573a2f48bfabe90b59841e942d9 244 Gene3D G3DSA:3.40.50.150 27 243 4.4E-38 T 29-03-2018 CWR56_RS08965 aec97573a2f48bfabe90b59841e942d9 244 SUPERFAMILY SSF53335 8 243 3.65E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS08965 aec97573a2f48bfabe90b59841e942d9 244 Pfam PF08241 Methyltransferase domain 47 141 8.4E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CWR56_RS05475 b3601e6a9626aebaaa26e6effe44850a 120 Pfam PF03780 Asp23 family, cell envelope-related function 7 102 2.3E-27 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 SUPERFAMILY SSF51569 2 290 8.06E-98 T 29-03-2018 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 PIRSF PIRSF001365 1 292 1.9E-90 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 Gene3D G3DSA:3.20.20.70 2 292 3.4E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 286 6.6E-104 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 8.9E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 8.9E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 8.9E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 8.9E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 Pfam PF00701 Dihydrodipicolinate synthetase family 3 287 8.7E-98 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 61.192 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16195 c10ee2fe56326f639659eae7e5476181 293 SMART SM01130 2 290 6.2E-129 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS05410 620031f70dfc0228a11904d8aca8e7b9 82 Pfam PF12637 TSCPD domain 4 76 6.5E-33 T 29-03-2018 IPR024434 TSCPD domain CWR56_RS05410 620031f70dfc0228a11904d8aca8e7b9 82 TIGRFAM TIGR03905 TIGR03905_4_Cys: uncharacterized protein TIGR03905 3 77 1.3E-34 T 29-03-2018 IPR023806 Conserved hypothetical protein CHP03905 CWR56_RS13700 042f393e9974322025060db5c3e915b3 405 Gene3D G3DSA:1.20.1250.20 6 205 2.2E-20 T 29-03-2018 CWR56_RS13700 042f393e9974322025060db5c3e915b3 405 SUPERFAMILY SSF103473 1 399 1.44E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS13700 042f393e9974322025060db5c3e915b3 405 Gene3D G3DSA:1.20.1250.20 208 396 2.2E-12 T 29-03-2018 CWR56_RS13700 042f393e9974322025060db5c3e915b3 405 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 87 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CWR56_RS13700 042f393e9974322025060db5c3e915b3 405 Pfam PF07690 Major Facilitator Superfamily 14 350 6.1E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS10665 81e2a50b7e961c580223abb6b3a8fd53 165 SMART SM00347 36 137 1.8E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10665 81e2a50b7e961c580223abb6b3a8fd53 165 Gene3D G3DSA:1.10.10.10 14 141 1.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10665 81e2a50b7e961c580223abb6b3a8fd53 165 SUPERFAMILY SSF46785 10 152 8.37E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10665 81e2a50b7e961c580223abb6b3a8fd53 165 Pfam PF01047 MarR family 43 101 5.1E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS15910 4f8fd95af936673931fe029a462446c6 74 Pfam PF03840 Preprotein translocase SecG subunit 4 71 9.2E-17 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR56_RS15910 4f8fd95af936673931fe029a462446c6 74 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 71 2.3E-18 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR56_RS15910 4f8fd95af936673931fe029a462446c6 74 PRINTS PR01651 Protein-export SecG membrane protein signature 53 74 1.8E-8 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR56_RS15910 4f8fd95af936673931fe029a462446c6 74 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.8E-8 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR56_RS15910 4f8fd95af936673931fe029a462446c6 74 PRINTS PR01651 Protein-export SecG membrane protein signature 37 53 1.8E-8 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 Gene3D G3DSA:2.40.50.140 5 68 0.0064 T 29-03-2018 CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 Gene3D G3DSA:2.40.50.140 75 168 1.9E-8 T 29-03-2018 CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 Gene3D G3DSA:1.10.10.10 221 279 3.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 Pfam PF13509 S1 domain 74 133 1.3E-5 T 29-03-2018 CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 Pfam PF13509 S1 domain 4 67 8.3E-19 T 29-03-2018 CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 PIRSF PIRSF012524 1 280 6.8E-75 T 29-03-2018 IPR014464 Conserved virulence factor B CWR56_RS04585 54a1fdb303bb7f57efb2952637d02f88 280 SUPERFAMILY SSF50249 143 216 3.09E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Pfam PF00817 impB/mucB/samB family 10 157 4.5E-49 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Gene3D G3DSA:3.30.1490.100 246 353 8.7E-27 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Hamap MF_01113 DNA polymerase IV [dinB]. 4 356 40.638 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Gene3D G3DSA:1.10.150.20 174 245 2.0E-19 T 29-03-2018 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Pfam PF11798 IMS family HHH motif 170 200 4.8E-6 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 SUPERFAMILY SSF100879 241 343 1.3E-26 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 SUPERFAMILY SSF56672 3 237 1.78E-88 T 29-03-2018 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Gene3D G3DSA:3.30.70.270 120 173 7.7E-19 T 29-03-2018 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Gene3D G3DSA:3.30.70.270 44 119 2.7E-23 T 29-03-2018 CWR56_RS04420 8319ec14b81445bd6033a150d17dd4d6 365 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 350 1.2E-23 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR56_RS11445 32ed7424c467c7dcdf5e3d8346e3b9ff 124 SUPERFAMILY SSF46785 9 123 4.81E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11445 32ed7424c467c7dcdf5e3d8346e3b9ff 124 Gene3D G3DSA:1.10.10.10 12 75 2.7E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11445 32ed7424c467c7dcdf5e3d8346e3b9ff 124 Pfam PF03965 Penicillinase repressor 13 116 6.9E-11 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR56_RS02995 627e3d8bb03aa5b208fb2c913c799b12 296 SUPERFAMILY SSF102114 26 213 1.83E-11 T 29-03-2018 CWR56_RS02995 627e3d8bb03aa5b208fb2c913c799b12 296 Pfam PF04055 Radical SAM superfamily 29 197 3.8E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS02995 627e3d8bb03aa5b208fb2c913c799b12 296 Gene3D G3DSA:3.20.20.70 6 294 2.3E-22 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS02995 627e3d8bb03aa5b208fb2c913c799b12 296 SMART SM00729 24 242 0.0052 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS00645 7ad7b6ee9ca80f203f324b4c2a1a6a51 102 Gene3D G3DSA:1.20.58.80 1 97 4.7E-38 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS00645 7ad7b6ee9ca80f203f324b4c2a1a6a51 102 SUPERFAMILY SSF46973 1 96 1.22E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS00645 7ad7b6ee9ca80f203f324b4c2a1a6a51 102 PIRSF PIRSF000699 1 102 6.0E-40 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS00645 7ad7b6ee9ca80f203f324b4c2a1a6a51 102 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 3 95 1.1E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS09730 e4fe21926b92f48b6cc31f2612fb7ede 363 Pfam PF01594 AI-2E family transporter 23 351 4.9E-38 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS09730 e4fe21926b92f48b6cc31f2612fb7ede 363 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 22 359 1.4E-63 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 4 121 1.6E-31 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 121 1.8E-29 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 Gene3D G3DSA:3.90.470.20 1 125 9.3E-35 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 6 119 1.7E-21 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 SUPERFAMILY SSF56214 3 121 1.14E-29 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 124 23.945 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR56_RS17275 4a7443ab80dfd955da28699d1139a7f3 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 87 2.0E-25 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR56_RS05360 f7e3b931ae4a565b424527ff72835675 185 PIRSF PIRSF037733 1 185 1.5E-61 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CWR56_RS05360 f7e3b931ae4a565b424527ff72835675 185 Pfam PF08220 DeoR-like helix-turn-helix domain 9 42 6.2E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR56_RS05360 f7e3b931ae4a565b424527ff72835675 185 Gene3D G3DSA:1.10.10.10 1 40 3.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05360 f7e3b931ae4a565b424527ff72835675 185 SUPERFAMILY SSF54637 74 181 1.1E-11 T 29-03-2018 IPR029069 HotDog domain CWR56_RS05360 f7e3b931ae4a565b424527ff72835675 185 Gene3D G3DSA:3.10.129.10 41 182 1.8E-9 T 29-03-2018 CWR56_RS08415 5f4338a269dfdd3b477b3690989399bf 196 SUPERFAMILY SSF46689 5 75 1.39E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS08415 5f4338a269dfdd3b477b3690989399bf 196 Gene3D G3DSA:1.10.10.60 9 51 3.9E-8 T 29-03-2018 CWR56_RS08415 5f4338a269dfdd3b477b3690989399bf 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 63 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS08415 5f4338a269dfdd3b477b3690989399bf 196 Gene3D G3DSA:1.10.10.60 52 184 2.1E-6 T 29-03-2018 CWR56_RS00585 38d33e73ae8999ea18f061198d75ff15 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 7 421 45.093 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS00585 38d33e73ae8999ea18f061198d75ff15 423 Gene3D G3DSA:3.65.10.10 27 225 2.6E-53 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR56_RS00585 38d33e73ae8999ea18f061198d75ff15 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7 419 2.4E-179 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS00585 38d33e73ae8999ea18f061198d75ff15 423 Gene3D G3DSA:3.65.10.10 226 423 1.4E-49 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR56_RS00585 38d33e73ae8999ea18f061198d75ff15 423 SUPERFAMILY SSF55205 7 422 3.92E-142 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWR56_RS00585 38d33e73ae8999ea18f061198d75ff15 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 409 8.2E-111 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 290 377 6.1E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 SUPERFAMILY SSF69189 281 376 1.75E-10 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 Gene3D G3DSA:3.40.710.10 20 285 3.1E-48 T 29-03-2018 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 SMART SM00936 289 379 6.9E-12 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 Gene3D G3DSA:2.60.410.10 289 379 2.5E-13 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 3.5E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 137 150 3.5E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 109 126 3.5E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 270 3.8E-58 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWR56_RS12620 eef37e2b06212991a56b837c047b2802 429 SUPERFAMILY SSF56601 6 289 1.97E-69 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS00750 27ffb01b610e5be8f697606ca023fa17 320 Pfam PF02517 CAAX protease self-immunity 154 244 2.3E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR56_RS03215 09fef1b9a26d5e339a0b0e2d2f67e1e9 166 Gene3D G3DSA:3.40.630.30 3 164 4.2E-25 T 29-03-2018 CWR56_RS03215 09fef1b9a26d5e339a0b0e2d2f67e1e9 166 SUPERFAMILY SSF55729 11 158 1.1E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS03215 09fef1b9a26d5e339a0b0e2d2f67e1e9 166 Pfam PF00583 Acetyltransferase (GNAT) family 38 137 5.4E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS00720 841548a0f84e47b0117d00b52b2a6da3 238 Gene3D G3DSA:3.30.420.40 1 138 7.4E-34 T 29-03-2018 CWR56_RS00720 841548a0f84e47b0117d00b52b2a6da3 238 Pfam PF00814 Glycoprotease family 32 193 9.7E-28 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR56_RS00720 841548a0f84e47b0117d00b52b2a6da3 238 SUPERFAMILY SSF53067 109 206 1.04E-9 T 29-03-2018 CWR56_RS00720 841548a0f84e47b0117d00b52b2a6da3 238 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 219 8.4E-51 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CWR56_RS00720 841548a0f84e47b0117d00b52b2a6da3 238 SUPERFAMILY SSF53067 1 101 6.47E-28 T 29-03-2018 CWR56_RS02975 347385941d99d37e1cdb639d569eb5c0 173 SUPERFAMILY SSF46785 4 171 8.25E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02975 347385941d99d37e1cdb639d569eb5c0 173 Gene3D G3DSA:1.10.10.10 1 93 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02975 347385941d99d37e1cdb639d569eb5c0 173 Pfam PF03551 Transcriptional regulator PadR-like family 8 79 3.8E-9 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR56_RS06275 caa95d801c63ed0ec098aea99d089e76 238 TIGRFAM TIGR03732 lanti_perm_MutE: lantibiotic protection ABC transporter permease subunit, MutE/EpiE family 4 238 2.1E-84 T 29-03-2018 IPR021205 Lantibiotic ABC transporter permease subunit, SpaE/MutE CWR56_RS05375 d29ec031de021a2d7ba7fb736f111a14 309 SUPERFAMILY SSF51412 3 305 3.97E-78 T 29-03-2018 CWR56_RS05375 d29ec031de021a2d7ba7fb736f111a14 309 Pfam PF03060 Nitronate monooxygenase 5 78 2.0E-22 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CWR56_RS05375 d29ec031de021a2d7ba7fb736f111a14 309 Pfam PF03060 Nitronate monooxygenase 80 298 7.7E-54 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CWR56_RS05375 d29ec031de021a2d7ba7fb736f111a14 309 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 2 304 2.9E-153 T 29-03-2018 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative CWR56_RS05375 d29ec031de021a2d7ba7fb736f111a14 309 Gene3D G3DSA:3.20.20.70 2 308 1.7E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS01555 a64b811e43c8e0d2c10345bcd42d1d30 332 Gene3D G3DSA:1.10.3470.10 43 324 9.9E-33 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS01555 a64b811e43c8e0d2c10345bcd42d1d30 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 317 4.8E-46 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWR56_RS14365 0303cd21fbd7880b5911aea97e039665 220 SUPERFAMILY SSF55486 35 218 2.2E-33 T 29-03-2018 CWR56_RS14365 0303cd21fbd7880b5911aea97e039665 220 Gene3D G3DSA:3.40.390.10 22 220 4.4E-37 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CWR56_RS14365 0303cd21fbd7880b5911aea97e039665 220 Pfam PF07737 Anthrax toxin lethal factor, N- and C-terminal domain 141 220 4.8E-5 T 29-03-2018 IPR014781 Anthrax toxin, lethal/endema factor, N-/C-terminal CWR56_RS07845 f40a33da8f6a35a405b8a86a95d6e8c5 317 SUPERFAMILY SSF81345 5 312 4.18E-64 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CWR56_RS07845 f40a33da8f6a35a405b8a86a95d6e8c5 317 Gene3D G3DSA:1.10.3470.10 4 317 2.3E-38 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS07845 f40a33da8f6a35a405b8a86a95d6e8c5 317 Pfam PF01032 FecCD transport family 10 311 1.7E-64 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR56_RS17535 7fd91f463094cba6423fa4377b5eea34 92 Gene3D G3DSA:3.30.1120.40 1 83 1.9E-35 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR56_RS17535 7fd91f463094cba6423fa4377b5eea34 92 SUPERFAMILY SSF160537 1 85 3.01E-34 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR56_RS17535 7fd91f463094cba6423fa4377b5eea34 92 Pfam PF04026 SpoVG 1 82 6.1E-37 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR56_RS17535 7fd91f463094cba6423fa4377b5eea34 92 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 89 26.379 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR56_RS04085 f4837ca51a416cdcd5dff2609dc9a2cd 331 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 222 241 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CWR56_RS04085 f4837ca51a416cdcd5dff2609dc9a2cd 331 SUPERFAMILY SSF53659 2 330 2.3E-131 T 29-03-2018 CWR56_RS04085 f4837ca51a416cdcd5dff2609dc9a2cd 331 SMART SM01329 3 326 1.9E-190 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR56_RS04085 f4837ca51a416cdcd5dff2609dc9a2cd 331 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 326 1.8E-110 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR56_RS04085 f4837ca51a416cdcd5dff2609dc9a2cd 331 Gene3D G3DSA:3.40.718.10 1 331 3.6E-141 T 29-03-2018 CWR56_RS15895 08dfd9ffd29b3968d087cbdc40a7ac05 165 Gene3D G3DSA:3.90.280.10 1 165 2.6E-35 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CWR56_RS15895 08dfd9ffd29b3968d087cbdc40a7ac05 165 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 27 158 3.5E-30 T 29-03-2018 IPR005247 YbhB/YbcL CWR56_RS15895 08dfd9ffd29b3968d087cbdc40a7ac05 165 Pfam PF01161 Phosphatidylethanolamine-binding protein 28 163 2.7E-25 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CWR56_RS15895 08dfd9ffd29b3968d087cbdc40a7ac05 165 SUPERFAMILY SSF49777 2 163 1.02E-28 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CWR56_RS14875 32261fc3892a67e9ca4597228f1b84cb 292 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS14875 32261fc3892a67e9ca4597228f1b84cb 292 SUPERFAMILY SSF52540 12 111 2.03E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14875 32261fc3892a67e9ca4597228f1b84cb 292 SUPERFAMILY SSF52540 152 269 2.03E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14875 32261fc3892a67e9ca4597228f1b84cb 292 SMART SM00382 38 263 1.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14875 32261fc3892a67e9ca4597228f1b84cb 292 Gene3D G3DSA:3.40.50.300 10 290 1.0E-53 T 29-03-2018 CWR56_RS14875 32261fc3892a67e9ca4597228f1b84cb 292 Pfam PF00005 ABC transporter 29 205 6.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06825 66796225a2cbbafad617fbee28da88e9 121 SUPERFAMILY SSF55620 2 119 8.45E-37 T 29-03-2018 CWR56_RS06825 66796225a2cbbafad617fbee28da88e9 121 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 8.0E-35 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR56_RS06825 66796225a2cbbafad617fbee28da88e9 121 TIGRFAM TIGR00526 folB_dom: FolB domain 1 120 2.8E-31 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR56_RS06825 66796225a2cbbafad617fbee28da88e9 121 Gene3D G3DSA:3.30.1130.10 1 121 7.1E-32 T 29-03-2018 CWR56_RS06825 66796225a2cbbafad617fbee28da88e9 121 Pfam PF02152 Dihydroneopterin aldolase 4 116 1.7E-32 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR56_RS06825 66796225a2cbbafad617fbee28da88e9 121 SMART SM00905 4 117 4.7E-47 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR56_RS10700 adb35e046f99bfa73d7000412abeb0b0 112 Gene3D G3DSA:1.10.3100.10 5 111 1.8E-18 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS10700 adb35e046f99bfa73d7000412abeb0b0 112 Pfam PF01381 Helix-turn-helix 12 66 2.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS10700 adb35e046f99bfa73d7000412abeb0b0 112 SUPERFAMILY SSF47413 6 68 2.01E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS10700 adb35e046f99bfa73d7000412abeb0b0 112 SMART SM00530 11 66 2.8E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS12180 2912c0010368ab1fe10616e75f5407b6 430 SUPERFAMILY SSF51735 15 155 4.36E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS12180 2912c0010368ab1fe10616e75f5407b6 430 Gene3D G3DSA:3.90.1210.10 389 424 0.014 T 29-03-2018 CWR56_RS12180 2912c0010368ab1fe10616e75f5407b6 430 Gene3D G3DSA:3.40.50.720 15 162 1.8E-19 T 29-03-2018 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 ProSitePatterns PS00760 Signal peptidases I lysine active site. 86 98 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 Gene3D G3DSA:2.10.109.10 24 177 5.3E-40 T 29-03-2018 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 Pfam PF00717 Peptidase S24-like 35 108 6.8E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 171 1.5E-45 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 2.9E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 84 96 2.9E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 129 148 2.9E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS02555 43a95661c7d99b89b490b87340ddc54d 178 SUPERFAMILY SSF51306 29 177 6.88E-44 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS05260 03f026305773a8555a56c238b98c6125 614 Pfam PF04055 Radical SAM superfamily 265 427 3.4E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS05260 03f026305773a8555a56c238b98c6125 614 SUPERFAMILY SSF102114 233 593 3.79E-53 T 29-03-2018 CWR56_RS05260 03f026305773a8555a56c238b98c6125 614 Gene3D G3DSA:3.20.20.70 161 575 2.5E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS05260 03f026305773a8555a56c238b98c6125 614 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 7 610 0.0 T 29-03-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM CWR56_RS05260 03f026305773a8555a56c238b98c6125 614 SMART SM00729 259 485 2.4E-27 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS14615 741511dd35f84baffbb01a92631272c2 340 Gene3D G3DSA:1.10.3470.10 6 340 1.8E-70 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS14615 741511dd35f84baffbb01a92631272c2 340 Pfam PF01032 FecCD transport family 21 337 4.8E-98 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR56_RS14615 741511dd35f84baffbb01a92631272c2 340 SUPERFAMILY SSF81345 6 337 2.35E-82 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CWR56_RS07815 1c55504e73d1047478e04da4c8909289 412 Pfam PF15609 Phosphoribosyl transferase 26 211 3.0E-60 T 29-03-2018 CWR56_RS07815 1c55504e73d1047478e04da4c8909289 412 PIRSF PIRSF020967 273 398 6.2E-12 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CWR56_RS07815 1c55504e73d1047478e04da4c8909289 412 PIRSF PIRSF020967 6 245 5.1E-26 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CWR56_RS07815 1c55504e73d1047478e04da4c8909289 412 Gene3D G3DSA:3.40.50.2020 26 210 5.4E-14 T 29-03-2018 CWR56_RS07815 1c55504e73d1047478e04da4c8909289 412 Pfam PF12500 TRSP domain C terminus to PRTase_2 265 396 2.5E-37 T 29-03-2018 IPR022537 TRSP domain CWR56_RS07815 1c55504e73d1047478e04da4c8909289 412 SUPERFAMILY SSF53271 32 180 1.99E-13 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS07130 e4440159914bb43aba7ca4cf0986f73c 215 Gene3D G3DSA:3.40.50.10420 10 176 1.2E-25 T 29-03-2018 CWR56_RS07130 e4440159914bb43aba7ca4cf0986f73c 215 Pfam PF02589 LUD domain 18 209 1.7E-55 T 29-03-2018 IPR003741 LUD domain CWR56_RS07130 e4440159914bb43aba7ca4cf0986f73c 215 PIRSF PIRSF020269 3 215 6.1E-71 T 29-03-2018 IPR009501 Uncharacterised conserved protein UCP020269 CWR56_RS07130 e4440159914bb43aba7ca4cf0986f73c 215 SUPERFAMILY SSF100950 11 157 1.05E-7 T 29-03-2018 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 206 2.0E-57 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 SUPERFAMILY SSF51569 1 211 3.98E-80 T 29-03-2018 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 1.2E-100 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.488 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CWR56_RS11575 2ab816f82c3504fe396b2da120a67e0e 216 Gene3D G3DSA:3.20.20.70 1 216 5.6E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 SUPERFAMILY SSF52540 9 168 2.44E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 Pfam PF01202 Shikimate kinase 15 163 1.0E-38 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 Gene3D G3DSA:3.40.50.300 3 176 2.1E-28 T 29-03-2018 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 PRINTS PR01100 Shikimate kinase family signature 33 46 1.3E-19 T 29-03-2018 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 PRINTS PR01100 Shikimate kinase family signature 60 68 1.3E-19 T 29-03-2018 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 PRINTS PR01100 Shikimate kinase family signature 99 116 1.3E-19 T 29-03-2018 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 PRINTS PR01100 Shikimate kinase family signature 9 24 1.3E-19 T 29-03-2018 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 PRINTS PR01100 Shikimate kinase family signature 78 87 1.3E-19 T 29-03-2018 CWR56_RS08870 cd6fbe7df464e11e4905119b85188aec 177 Hamap MF_00109 Shikimate kinase [aroK]. 6 167 22.903 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 Gene3D G3DSA:1.10.10.60 174 232 7.4E-15 T 29-03-2018 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 SUPERFAMILY SSF51215 26 163 3.27E-14 T 29-03-2018 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 SMART SM00342 199 282 8.0E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 236 278 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 282 1.8E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 266 1.8E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 Pfam PF12833 Helix-turn-helix domain 205 283 5.6E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 Gene3D G3DSA:2.60.120.280 2 167 2.9E-21 T 29-03-2018 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 SUPERFAMILY SSF46689 235 287 9.41E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 SUPERFAMILY SSF46689 184 232 4.93E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 Gene3D G3DSA:1.10.10.60 233 291 1.9E-16 T 29-03-2018 CWR56_RS09640 35259ba14d4f65bc94a507422d92b05c 298 Pfam PF02311 AraC-like ligand binding domain 17 158 3.4E-16 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWR56_RS05280 1ba55be70e2f874388b132d358b311e3 105 Pfam PF04327 Cysteine protease Prp 1 101 6.4E-24 T 29-03-2018 IPR007422 Cysteine protease Prp CWR56_RS05280 1ba55be70e2f874388b132d358b311e3 105 SUPERFAMILY SSF118010 1 104 1.44E-28 T 29-03-2018 IPR007422 Cysteine protease Prp CWR56_RS05280 1ba55be70e2f874388b132d358b311e3 105 Gene3D G3DSA:3.30.70.1490 1 105 5.0E-28 T 29-03-2018 IPR007422 Cysteine protease Prp CWR56_RS01800 5aaa68a4971dc08d4cba9cab89a4bda3 270 SMART SM00954 45 164 2.4E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR56_RS01800 5aaa68a4971dc08d4cba9cab89a4bda3 270 Pfam PF04607 Region found in RelA / SpoT proteins 45 161 2.4E-35 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR56_RS01800 5aaa68a4971dc08d4cba9cab89a4bda3 270 SUPERFAMILY SSF81301 6 197 1.96E-53 T 29-03-2018 CWR56_RS01800 5aaa68a4971dc08d4cba9cab89a4bda3 270 Gene3D G3DSA:1.10.287.860 147 195 1.8E-18 T 29-03-2018 CWR56_RS01800 5aaa68a4971dc08d4cba9cab89a4bda3 270 Gene3D G3DSA:3.30.460.10 1 145 8.3E-36 T 29-03-2018 CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 SUPERFAMILY SSF55031 208 319 2.39E-24 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 Gene3D G3DSA:3.40.630.10 2 405 6.8E-48 T 29-03-2018 CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 Pfam PF01546 Peptidase family M20/M25/M40 85 400 5.9E-27 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 SUPERFAMILY SSF53187 6 218 1.6E-71 T 29-03-2018 CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 SUPERFAMILY SSF53187 330 402 1.6E-71 T 29-03-2018 CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 PIRSF PIRSF001235 4 405 2.7E-119 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 Pfam PF07687 Peptidase dimerisation domain 208 309 5.5E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS09685 6b6dba83fbadd16fced801a59d1237de 405 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 10 398 2.4E-114 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CWR56_RS13260 98b8d64d8149dee9582cbb996f52b46c 211 Pfam PF12700 HlyD family secretion protein 1 211 4.7E-139 T 29-03-2018 IPR032681 HlyD family secretion protein CWR56_RS14155 b58a44cf688563348f26fabe6464928b 235 Gene3D G3DSA:3.40.50.10320 3 226 1.4E-21 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR56_RS14155 b58a44cf688563348f26fabe6464928b 235 SUPERFAMILY SSF102588 5 201 3.79E-17 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR56_RS14155 b58a44cf688563348f26fabe6464928b 235 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 151 1.8E-17 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CWR56_RS19000 d44b1a49694174a8ab54ff285e0b6dc2 252 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 231 31.736 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR56_RS19000 d44b1a49694174a8ab54ff285e0b6dc2 252 SUPERFAMILY SSF69796 1 232 4.71E-67 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR56_RS19000 d44b1a49694174a8ab54ff285e0b6dc2 252 Gene3D G3DSA:1.10.533.10 85 167 5.5E-4 T 29-03-2018 CWR56_RS19000 d44b1a49694174a8ab54ff285e0b6dc2 252 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 2 222 8.0E-60 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR56_RS19000 d44b1a49694174a8ab54ff285e0b6dc2 252 Pfam PF02511 Thymidylate synthase complementing protein 4 217 1.1E-72 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR56_RS16235 3e44b5865429dd9064a882368dd06818 179 Pfam PF00156 Phosphoribosyl transferase domain 8 161 5.0E-25 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS16235 3e44b5865429dd9064a882368dd06818 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 10 174 2.8E-60 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CWR56_RS16235 3e44b5865429dd9064a882368dd06818 179 SUPERFAMILY SSF53271 8 176 1.97E-53 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS16235 3e44b5865429dd9064a882368dd06818 179 Gene3D G3DSA:3.40.50.2020 1 179 4.6E-41 T 29-03-2018 CWR56_RS03470 c6b97516fed1f27c96d28540c18105a5 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 232 2.1E-17 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CWR56_RS03470 c6b97516fed1f27c96d28540c18105a5 259 SUPERFAMILY SSF52540 1 255 1.18E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03470 c6b97516fed1f27c96d28540c18105a5 259 Gene3D G3DSA:3.40.50.300 1 256 7.9E-43 T 29-03-2018 CWR56_RS03470 c6b97516fed1f27c96d28540c18105a5 259 PIRSF PIRSF005647 1 258 5.4E-81 T 29-03-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.8E-16 T 29-03-2018 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.8E-16 T 29-03-2018 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 265 1.8E-16 T 29-03-2018 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.8E-16 T 29-03-2018 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 165 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 253 271 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 3.0E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 278 3.1E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 Gene3D G3DSA:3.50.50.60 185 295 1.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 Gene3D G3DSA:3.50.50.60 116 152 8.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 SUPERFAMILY SSF51905 4 291 5.1E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08085 b1c7392c952440d1c011763290255dd2 295 Gene3D G3DSA:3.50.50.60 2 111 3.6E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 SMART SM00448 2 112 6.8E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 9.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 SMART SM00862 147 222 2.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 SUPERFAMILY SSF52172 2 125 1.85E-33 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 SUPERFAMILY SSF46894 126 222 1.08E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 Gene3D G3DSA:1.10.10.10 122 223 6.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 Gene3D G3DSA:3.40.50.2300 2 121 2.6E-28 T 29-03-2018 CWR56_RS14935 8cbe8bcb15912bd4e4da6777ac1edbe8 223 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS06805 500387a1ce1bed88162e9b54097c7faa 247 Gene3D G3DSA:3.20.10.10 96 247 1.9E-34 T 29-03-2018 CWR56_RS06805 500387a1ce1bed88162e9b54097c7faa 247 ProSitePatterns PS00770 Aminotransferases class-IV signature. 153 182 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR56_RS06805 500387a1ce1bed88162e9b54097c7faa 247 SUPERFAMILY SSF56752 11 246 2.88E-54 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR56_RS06805 500387a1ce1bed88162e9b54097c7faa 247 Pfam PF01063 Amino-transferase class IV 17 227 4.4E-45 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR56_RS06805 500387a1ce1bed88162e9b54097c7faa 247 Gene3D G3DSA:3.30.470.10 2 95 1.1E-10 T 29-03-2018 CWR56_RS03635 45b4d98cc9b6e8f08e55a3a7984018b3 688 Gene3D G3DSA:3.40.50.300 6 284 5.8E-50 T 29-03-2018 CWR56_RS03635 45b4d98cc9b6e8f08e55a3a7984018b3 688 Gene3D G3DSA:3.40.50.300 285 388 6.8E-20 T 29-03-2018 CWR56_RS03635 45b4d98cc9b6e8f08e55a3a7984018b3 688 Gene3D G3DSA:3.40.50.300 396 622 1.6E-33 T 29-03-2018 CWR56_RS03635 45b4d98cc9b6e8f08e55a3a7984018b3 688 Pfam PF13361 UvrD-like helicase C-terminal domain 280 611 6.4E-46 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR56_RS03635 45b4d98cc9b6e8f08e55a3a7984018b3 688 SUPERFAMILY SSF52540 13 614 5.32E-133 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03635 45b4d98cc9b6e8f08e55a3a7984018b3 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 274 1.1E-57 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR56_RS09160 d64259319bfc0b609cb03df9c2d53a92 400 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 10 397 9.1E-134 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR56_RS09160 d64259319bfc0b609cb03df9c2d53a92 400 SUPERFAMILY SSF53383 8 398 4.74E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS09160 d64259319bfc0b609cb03df9c2d53a92 400 Gene3D G3DSA:3.40.640.10 106 258 1.2E-21 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS09160 d64259319bfc0b609cb03df9c2d53a92 400 Gene3D G3DSA:3.90.1150.10 6 105 6.7E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS09160 d64259319bfc0b609cb03df9c2d53a92 400 Pfam PF00155 Aminotransferase class I and II 45 383 4.8E-41 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS09160 d64259319bfc0b609cb03df9c2d53a92 400 Gene3D G3DSA:3.90.1150.10 259 399 1.6E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS17665 3554a2b1ac8affaa81c1038692cdb3cc 476 PIRSF PIRSF000484 1 475 4.2E-158 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CWR56_RS17665 3554a2b1ac8affaa81c1038692cdb3cc 476 SUPERFAMILY SSF54675 3 134 1.69E-49 T 29-03-2018 CWR56_RS17665 3554a2b1ac8affaa81c1038692cdb3cc 476 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 153 336 6.6E-8 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CWR56_RS17665 3554a2b1ac8affaa81c1038692cdb3cc 476 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 462 2.0E-176 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CWR56_RS17665 3554a2b1ac8affaa81c1038692cdb3cc 476 Gene3D G3DSA:3.20.140.10 1 383 1.1E-130 T 29-03-2018 CWR56_RS17665 3554a2b1ac8affaa81c1038692cdb3cc 476 SUPERFAMILY SSF51690 135 473 3.83E-124 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 69 1.7E-6 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 SUPERFAMILY SSF46767 76 164 2.88E-27 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 132 138 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 77 161 6.0E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 78 163 5.4E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 Gene3D G3DSA:1.10.10.10 72 164 3.4E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 162 36.944 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 SUPERFAMILY SSF53155 3 81 3.34E-19 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR56_RS02805 b7fe513c6ed98c258328978bab555e39 177 Gene3D G3DSA:3.30.160.70 1 71 1.1E-20 T 29-03-2018 CWR56_RS01320 03917916d6b2031366f7318afdfc4e21 147 Pfam PF03748 Flagellar basal body-associated protein FliL 57 147 4.1E-17 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CWR56_RS11600 6ed2ab8aa4efc411a6383afd46861200 474 Pfam PF02378 Phosphotransferase system, EIIC 22 280 1.0E-18 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS11600 6ed2ab8aa4efc411a6383afd46861200 474 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 13 346 3.8E-159 T 29-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS11600 6ed2ab8aa4efc411a6383afd46861200 474 Gene3D G3DSA:3.40.50.2300 382 474 2.1E-17 T 29-03-2018 CWR56_RS11600 6ed2ab8aa4efc411a6383afd46861200 474 SUPERFAMILY SSF52794 383 471 6.28E-22 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11600 6ed2ab8aa4efc411a6383afd46861200 474 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 386 469 1.8E-10 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 178 20.415 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 Gene3D G3DSA:1.10.520.20 2 107 5.1E-24 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 PRINTS PR00125 ATP synthase delta subunit signature 136 151 4.4E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 PRINTS PR00125 ATP synthase delta subunit signature 75 86 4.4E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 PRINTS PR00125 ATP synthase delta subunit signature 5 24 4.4E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 PRINTS PR00125 ATP synthase delta subunit signature 86 100 4.4E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 PRINTS PR00125 ATP synthase delta subunit signature 151 169 4.4E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 5 176 1.5E-47 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 SUPERFAMILY SSF47928 2 106 8.63E-24 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS17300 a86281eaa4b915da28d34232b0be1688 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 5 176 8.0E-41 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR56_RS16400 b49217083834144cc4d7e78afe3dffc0 254 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16400 b49217083834144cc4d7e78afe3dffc0 254 SUPERFAMILY SSF52540 9 240 3.51E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16400 b49217083834144cc4d7e78afe3dffc0 254 Pfam PF00005 ABC transporter 24 179 1.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16400 b49217083834144cc4d7e78afe3dffc0 254 SMART SM00382 33 241 7.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16400 b49217083834144cc4d7e78afe3dffc0 254 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 9 254 8.3E-129 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CWR56_RS16400 b49217083834144cc4d7e78afe3dffc0 254 Gene3D G3DSA:3.40.50.300 4 252 1.4E-58 T 29-03-2018 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 Gene3D G3DSA:3.30.950.10 113 225 1.1E-41 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 SUPERFAMILY SSF53790 3 220 2.75E-81 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 82 93 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 222 36.632 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 5 275 1.9E-89 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 201 5.4E-26 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 Gene3D G3DSA:3.40.1010.10 2 112 3.9E-43 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17680 e33f5fac00f0e74e9eda6f33406ec7ae 277 PIRSF PIRSF005917 1 277 1.2E-103 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR56_RS02790 1679e19dd9f1b5702cefd1b8ee5522f3 190 Gene3D G3DSA:1.20.1260.10 1 182 8.2E-48 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS02790 1679e19dd9f1b5702cefd1b8ee5522f3 190 SUPERFAMILY SSF47240 1 187 6.64E-63 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS02790 1679e19dd9f1b5702cefd1b8ee5522f3 190 Pfam PF05067 Manganese containing catalase 1 181 2.6E-52 T 29-03-2018 IPR007760 Manganese catalase CWR56_RS04355 5604cbe9e0c9b863f94ec9885853d7f8 621 SUPERFAMILY SSF51445 130 536 4.82E-95 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS04355 5604cbe9e0c9b863f94ec9885853d7f8 621 Gene3D G3DSA:3.20.20.80 128 536 1.5E-95 T 29-03-2018 CWR56_RS04355 5604cbe9e0c9b863f94ec9885853d7f8 621 SUPERFAMILY SSF51011 536 620 2.58E-7 T 29-03-2018 CWR56_RS04355 5604cbe9e0c9b863f94ec9885853d7f8 621 Gene3D G3DSA:2.60.40.1180 537 621 5.1E-9 T 29-03-2018 CWR56_RS04355 5604cbe9e0c9b863f94ec9885853d7f8 621 Pfam PF00128 Alpha amylase, catalytic domain 193 501 1.4E-67 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS04355 5604cbe9e0c9b863f94ec9885853d7f8 621 SMART SM00642 143 527 4.7E-78 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR56_RS17675 8ecccb5727a8675f6fad129769db8f25 234 TIGRFAM TIGR00277 HDIG: HDIG domain 83 147 1.3E-8 T 29-03-2018 IPR006675 HDIG domain CWR56_RS17675 8ecccb5727a8675f6fad129769db8f25 234 Pfam PF01966 HD domain 81 173 3.7E-8 T 29-03-2018 IPR006674 HD domain CWR56_RS17675 8ecccb5727a8675f6fad129769db8f25 234 Gene3D G3DSA:1.10.3090.10 1 224 2.1E-12 T 29-03-2018 CWR56_RS17675 8ecccb5727a8675f6fad129769db8f25 234 SUPERFAMILY SSF109604 88 173 6.28E-10 T 29-03-2018 CWR56_RS13810 1ba5770e2d2182e6fb6b797ca1400e11 232 Gene3D G3DSA:3.20.20.370 20 232 2.3E-47 T 29-03-2018 CWR56_RS13810 1ba5770e2d2182e6fb6b797ca1400e11 232 SUPERFAMILY SSF88713 12 230 5.93E-49 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS13810 1ba5770e2d2182e6fb6b797ca1400e11 232 Pfam PF01522 Polysaccharide deacetylase 37 143 9.9E-23 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS07310 31e4af904f2b3d8883a84931a015efa7 217 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 3 212 20.662 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CWR56_RS07310 31e4af904f2b3d8883a84931a015efa7 217 Pfam PF02525 Flavodoxin-like fold 3 208 7.9E-33 T 29-03-2018 IPR003680 Flavodoxin-like fold CWR56_RS07310 31e4af904f2b3d8883a84931a015efa7 217 Gene3D G3DSA:3.40.50.360 2 217 2.9E-27 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS07310 31e4af904f2b3d8883a84931a015efa7 217 SUPERFAMILY SSF52218 2 213 1.28E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS13605 59a899388f33f17ae1ee0a8205155150 73 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 67 3.2E-26 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CWR56_RS13605 59a899388f33f17ae1ee0a8205155150 73 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CWR56_RS11855 19d212b602e202e6ed99ca1abfcfeac2 74 Gene3D G3DSA:1.10.10.10 4 74 6.6E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11690 835e502cc470d612c2381f6474e7346a 428 PIRSF PIRSF011588 1 428 1.8E-217 T 29-03-2018 IPR016585 Glycine/sarcosine/betaine reductase, component B, fused alpha/beta GO:0050485|GO:0055114 CWR56_RS11690 835e502cc470d612c2381f6474e7346a 428 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 1 426 7.1E-211 T 29-03-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 Gene3D G3DSA:3.40.50.2300 1 129 9.3E-21 T 29-03-2018 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 Gene3D G3DSA:2.40.50.40 130 197 3.1E-20 T 29-03-2018 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 Pfam PF04397 LytTr DNA-binding domain 138 227 1.3E-22 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 Gene3D G3DSA:2.20.25.10 205 228 6.2E-4 T 29-03-2018 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 SUPERFAMILY SSF52172 1 133 1.08E-21 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 SMART SM00448 2 116 2.4E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 SMART SM00850 137 229 4.9E-29 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS05040 67c6ce54fcb7c88eed3e025c1e3e22fe 237 Pfam PF00072 Response regulator receiver domain 4 116 2.5E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02010 5d18148eb174ccd53a9608c4172e6804 67 Pfam PF14020 Protein of unknown function (DUF4236) 3 57 2.3E-21 T 29-03-2018 IPR025330 Domain of unknown function DUF4236 CWR56_RS18995 836a97037718808fcb43fd0815f2c60b 131 Gene3D G3DSA:1.10.1520.10 3 131 1.7E-21 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS18995 836a97037718808fcb43fd0815f2c60b 131 PIRSF PIRSF005520 1 131 2.5E-50 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CWR56_RS18995 836a97037718808fcb43fd0815f2c60b 131 Pfam PF00636 Ribonuclease III domain 13 111 4.3E-18 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS18995 836a97037718808fcb43fd0815f2c60b 131 SUPERFAMILY SSF69065 8 126 1.29E-37 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS18995 836a97037718808fcb43fd0815f2c60b 131 SMART SM00535 3 131 0.0015 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR56_RS18995 836a97037718808fcb43fd0815f2c60b 131 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 3 128 30.442 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CWR56_RS18955 7ffb179c32069b3cfd02f7eb1e466176 310 Gene3D G3DSA:3.30.930.10 1 245 5.7E-58 T 29-03-2018 CWR56_RS18955 7ffb179c32069b3cfd02f7eb1e466176 310 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 152 3.7E-7 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR56_RS18955 7ffb179c32069b3cfd02f7eb1e466176 310 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 5 269 4.2E-67 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CWR56_RS18955 7ffb179c32069b3cfd02f7eb1e466176 310 SUPERFAMILY SSF55681 1 238 2.49E-62 T 29-03-2018 CWR56_RS14070 309fbfbc7a2bdad304572e093a9602ca 249 Gene3D G3DSA:3.90.550.10 4 217 3.4E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14070 309fbfbc7a2bdad304572e093a9602ca 249 SUPERFAMILY SSF53448 5 224 9.57E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14070 309fbfbc7a2bdad304572e093a9602ca 249 Pfam PF00535 Glycosyl transferase family 2 7 148 7.2E-40 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS07505 53ff7d1f3735bf89ded6747b2609b8cf 89 Pfam PF08765 Mor transcription activator family 12 87 5.1E-6 T 29-03-2018 IPR014875 Mor transcription activator CWR56_RS07505 53ff7d1f3735bf89ded6747b2609b8cf 89 Gene3D G3DSA:1.10.10.60 45 88 2.8E-11 T 29-03-2018 CWR56_RS07505 53ff7d1f3735bf89ded6747b2609b8cf 89 SUPERFAMILY SSF46689 1 87 1.97E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS01425 5ab67cd2941c0b7cd7952bf5fbce7d9c 130 Pfam PF01638 HxlR-like helix-turn-helix 26 116 1.2E-28 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS01425 5ab67cd2941c0b7cd7952bf5fbce7d9c 130 Gene3D G3DSA:1.10.10.10 24 118 3.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01425 5ab67cd2941c0b7cd7952bf5fbce7d9c 130 SUPERFAMILY SSF46785 12 115 5.46E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05620 8b7e1d438e08e13841fdb543a7df0f54 554 Gene3D G3DSA:3.40.710.10 221 553 2.9E-79 T 29-03-2018 CWR56_RS05620 8b7e1d438e08e13841fdb543a7df0f54 554 Gene3D G3DSA:3.90.1310.10 28 220 2.5E-28 T 29-03-2018 CWR56_RS05620 8b7e1d438e08e13841fdb543a7df0f54 554 SUPERFAMILY SSF56519 52 197 3.79E-20 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS05620 8b7e1d438e08e13841fdb543a7df0f54 554 SUPERFAMILY SSF56601 173 552 3.82E-74 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS05620 8b7e1d438e08e13841fdb543a7df0f54 554 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 192 8.9E-10 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR56_RS05620 8b7e1d438e08e13841fdb543a7df0f54 554 Pfam PF00905 Penicillin binding protein transpeptidase domain 250 550 6.3E-60 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR56_RS00180 c96ceb10e0271ce4ec9a180849e67144 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 145 2.7E-36 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CWR56_RS00180 c96ceb10e0271ce4ec9a180849e67144 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00180 c96ceb10e0271ce4ec9a180849e67144 147 Gene3D G3DSA:3.100.10.10 41 147 4.0E-31 T 29-03-2018 CWR56_RS00180 c96ceb10e0271ce4ec9a180849e67144 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 147 21.855 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CWR56_RS00180 c96ceb10e0271ce4ec9a180849e67144 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 2.7E-51 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00180 c96ceb10e0271ce4ec9a180849e67144 147 SUPERFAMILY SSF52080 4 144 9.42E-46 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CWR56_RS09935 a283660cf930f43819213c700f5e1cc3 425 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 266 346 5.6E-9 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS09935 a283660cf930f43819213c700f5e1cc3 425 Pfam PF01385 Probable transposase 183 299 7.7E-31 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 Gene3D G3DSA:3.30.70.1350 206 295 3.8E-19 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 SUPERFAMILY SSF160240 209 288 5.23E-20 T 29-03-2018 CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 Pfam PF01545 Cation efflux family 13 206 4.2E-48 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 289 2.2E-74 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 Gene3D G3DSA:1.20.1510.10 7 205 6.7E-51 T 29-03-2018 CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 Pfam PF16916 Dimerisation domain of Zinc Transporter 211 288 6.7E-22 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS17555 abb23c3ff79100f75f29574575dc89ca 298 SUPERFAMILY SSF161111 5 207 7.98E-57 T 29-03-2018 CWR56_RS07895 fba98dbacaf4a94a8f8a2e5afb80a14a 171 Pfam PF13787 Protein of unknown function with HXXEE motif 6 123 5.3E-23 T 29-03-2018 IPR025671 Protein of unknown function with HXXEE motif CWR56_RS16150 190c7f2e6f16ccea2df964ab8bec2b9b 253 SMART SM00382 29 218 2.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16150 190c7f2e6f16ccea2df964ab8bec2b9b 253 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16150 190c7f2e6f16ccea2df964ab8bec2b9b 253 Pfam PF00005 ABC transporter 21 166 2.7E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16150 190c7f2e6f16ccea2df964ab8bec2b9b 253 SUPERFAMILY SSF52540 4 239 2.26E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16150 190c7f2e6f16ccea2df964ab8bec2b9b 253 Gene3D G3DSA:3.40.50.300 1 253 1.7E-72 T 29-03-2018 CWR56_RS06280 e6c143217259dfed0b69228e6909a2e3 252 TIGRFAM TIGR03733 lanti_perm_MutG: lantibiotic protection ABC transporter permease subunit, MutG family 6 249 1.1E-87 T 29-03-2018 IPR022294 Lantibiotic protection ABC transporter permease subunit, MutG family CWR56_RS06280 e6c143217259dfed0b69228e6909a2e3 252 Pfam PF12730 ABC-2 family transporter protein 12 169 8.4E-7 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS13765 e2d6511ac8cf8aa52cdd6f5ae2dc57ca 225 Pfam PF04203 Sortase family 62 224 2.7E-23 T 29-03-2018 IPR005754 Sortase family CWR56_RS13765 e2d6511ac8cf8aa52cdd6f5ae2dc57ca 225 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 4 220 1.3E-65 T 29-03-2018 IPR009835 Sortase B family CWR56_RS13765 e2d6511ac8cf8aa52cdd6f5ae2dc57ca 225 SUPERFAMILY SSF63817 4 225 1.57E-59 T 29-03-2018 IPR023365 Sortase domain CWR56_RS13765 e2d6511ac8cf8aa52cdd6f5ae2dc57ca 225 Gene3D G3DSA:2.40.260.10 43 225 3.8E-63 T 29-03-2018 IPR023365 Sortase domain CWR56_RS18950 78385ae68e47cd15742118439dddfef1 216 SUPERFAMILY SSF53639 3 209 2.75E-61 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS18950 78385ae68e47cd15742118439dddfef1 216 Gene3D G3DSA:3.40.225.10 3 216 9.3E-58 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS18950 78385ae68e47cd15742118439dddfef1 216 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 184 1.7E-45 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS18950 78385ae68e47cd15742118439dddfef1 216 SMART SM01007 8 185 2.0E-57 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Gene3D G3DSA:2.30.30.410 18 91 1.1E-13 T 29-03-2018 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Pfam PF08239 Bacterial SH3 domain 250 300 7.9E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Pfam PF08239 Bacterial SH3 domain 33 83 1.4E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Pfam PF08239 Bacterial SH3 domain 173 223 7.5E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Pfam PF08239 Bacterial SH3 domain 105 154 3.6E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 SUPERFAMILY SSF50044 122 177 4.24E-6 T 29-03-2018 IPR001452 SH3 domain GO:0005515 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Gene3D G3DSA:2.40.50.110 92 156 3.1E-19 T 29-03-2018 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Gene3D G3DSA:2.40.50.110 157 223 3.6E-21 T 29-03-2018 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Gene3D G3DSA:2.40.50.110 224 302 3.2E-19 T 29-03-2018 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 SMART SM00047 439 598 1.9E-15 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 452 588 6.2E-14 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 SMART SM00287 24 87 4.3E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 SMART SM00287 240 303 3.7E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 SMART SM00287 164 226 4.4E-17 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 SMART SM00287 97 158 3.6E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS06055 f03bbbdb24fcab38d59b1aac3b765ce6 607 Gene3D G3DSA:1.10.530.10 440 590 7.7E-27 T 29-03-2018 CWR56_RS02980 1a1a23bfe81b4098fd60540d368d388d 359 SUPERFAMILY SSF48371 28 235 6.33E-46 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWR56_RS02980 1a1a23bfe81b4098fd60540d368d388d 359 Gene3D G3DSA:1.25.40.290 128 238 1.4E-24 T 29-03-2018 CWR56_RS02980 1a1a23bfe81b4098fd60540d368d388d 359 Pfam PF08713 DNA alkylation repair enzyme 123 210 1.0E-7 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CWR56_RS16830 142a01d081c5a044cccb4307d92e16a6 459 Pfam PF01554 MatE 37 198 9.7E-21 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS16830 142a01d081c5a044cccb4307d92e16a6 459 Pfam PF01554 MatE 260 410 2.4E-15 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS16830 142a01d081c5a044cccb4307d92e16a6 459 PIRSF PIRSF006603 17 459 1.6E-55 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS15125 14e4437ec27e5f62a28b3b8cfa24df53 250 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 6.3E-17 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CWR56_RS15125 14e4437ec27e5f62a28b3b8cfa24df53 250 Gene3D G3DSA:3.30.870.10 119 226 0.0011 T 29-03-2018 CWR56_RS15125 14e4437ec27e5f62a28b3b8cfa24df53 250 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 229 3.4E-9 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal CWR56_RS15125 14e4437ec27e5f62a28b3b8cfa24df53 250 Gene3D G3DSA:1.10.10.10 4 118 4.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15125 14e4437ec27e5f62a28b3b8cfa24df53 250 SUPERFAMILY SSF46785 2 66 1.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02540 9699548e48adc8303f351a25e2ce9c35 238 Pfam PF13367 Protease prsW family 29 209 4.0E-42 T 29-03-2018 IPR026898 Protease PrsW GO:0008233 CWR56_RS02540 9699548e48adc8303f351a25e2ce9c35 238 PIRSF PIRSF016933 2 232 4.2E-86 T 29-03-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 CWR56_RS08635 513f4fd8f5f4b2dcf0d3d466aa71ae1d 122 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 12 118 1.8E-24 T 29-03-2018 IPR010181 CGCAxxGCC motif CWR56_RS08635 513f4fd8f5f4b2dcf0d3d466aa71ae1d 122 SUPERFAMILY SSF48695 7 67 5.02E-9 T 29-03-2018 IPR011031 Multihaem cytochrome CWR56_RS08635 513f4fd8f5f4b2dcf0d3d466aa71ae1d 122 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 12 116 3.6E-17 T 29-03-2018 IPR010181 CGCAxxGCC motif CWR56_RS03505 a71cdeb9a97e305bb239d90c0dfcff40 256 PIRSF PIRSF005647 3 256 1.7E-65 T 29-03-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type CWR56_RS03505 a71cdeb9a97e305bb239d90c0dfcff40 256 SUPERFAMILY SSF52540 1 253 1.91E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03505 a71cdeb9a97e305bb239d90c0dfcff40 256 Gene3D G3DSA:3.40.50.300 4 256 7.6E-34 T 29-03-2018 CWR56_RS03505 a71cdeb9a97e305bb239d90c0dfcff40 256 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 232 7.2E-14 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CWR56_RS16205 449446b980cc58d4375d91a122240483 295 Pfam PF00701 Dihydrodipicolinate synthetase family 3 284 4.6E-92 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 285 6.2E-105 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 PIRSF PIRSF001365 1 295 6.3E-90 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 62.293 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 SUPERFAMILY SSF51569 1 290 1.36E-99 T 29-03-2018 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 SMART SM01130 2 290 8.9E-132 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 Gene3D G3DSA:3.20.20.70 2 295 4.1E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 2.7E-30 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 2.7E-30 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 2.7E-30 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS16205 449446b980cc58d4375d91a122240483 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 2.7E-30 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 Pfam PF02195 ParB-like nuclease domain 8 95 1.1E-24 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 Gene3D G3DSA:3.90.1530.10 1 96 1.7E-36 T 29-03-2018 CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 SUPERFAMILY SSF110849 6 145 1.67E-31 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 6 260 6.3E-106 T 29-03-2018 IPR023705 Nucleoid occlusion protein CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 4 173 1.5E-55 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 Gene3D G3DSA:1.10.10.730 97 144 1.0E-16 T 29-03-2018 CWR56_RS18395 ede2d51c8c55029c8a6d7af381f44069 261 SMART SM00470 7 96 3.3E-32 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS07685 d21b282be6eb8ba9b6650caeb1e76daa 122 SMART SM00345 15 74 3.6E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS07685 d21b282be6eb8ba9b6650caeb1e76daa 122 SUPERFAMILY SSF46785 5 84 5.93E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07685 d21b282be6eb8ba9b6650caeb1e76daa 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 5.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS07685 d21b282be6eb8ba9b6650caeb1e76daa 122 Gene3D G3DSA:1.10.10.10 1 88 2.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04980 a2b37fd89b41426c4f49d898da4a6918 254 Pfam PF03609 PTS system sorbose-specific iic component 6 237 1.7E-69 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWR56_RS11315 79d90eefaac34a4001f1f391f64181ae 140 Gene3D G3DSA:3.30.530.20 1 139 5.7E-4 T 29-03-2018 IPR023393 START-like domain CWR56_RS11315 79d90eefaac34a4001f1f391f64181ae 140 Pfam PF11687 Domain of unknown function (DUF3284) 1 115 1.8E-25 T 29-03-2018 IPR021701 Protein of unknown function DUF3284 CWR56_RS17325 73af6ee027734a5f8a3401cbb038b3b0 75 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 14 66 3.2E-17 T 29-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 SMART SM00155 406 433 1.5E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 SMART SM00155 223 250 6.3E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 SUPERFAMILY SSF56024 275 478 2.69E-44 T 29-03-2018 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 PIRSF PIRSF000850 96 193 0.0034 T 29-03-2018 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 PIRSF PIRSF000850 295 492 0.081 T 29-03-2018 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 Pfam PF13091 PLD-like domain 333 460 2.7E-23 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 Pfam PF13091 PLD-like domain 140 256 1.7E-17 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 Pfam PF13396 Phospholipase_D-nuclease N-terminal 21 64 8.3E-9 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 Gene3D G3DSA:3.30.870.10 90 289 1.3E-34 T 29-03-2018 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 Gene3D G3DSA:3.30.870.10 322 489 2.2E-25 T 29-03-2018 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 14 493 8.2E-158 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 SUPERFAMILY SSF56024 101 321 1.76E-49 T 29-03-2018 CWR56_RS16945 d8f9fa4162fa8645a331ac4f0580fc3b 493 Hamap MF_01916 Cardiolipin synthase. 17 493 41.792 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 SUPERFAMILY SSF51556 59 339 2.85E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 TIGRFAM TIGR03314 Se_ssnA: putative selenium metabolism protein SsnA 2 442 4.0E-191 T 29-03-2018 IPR017700 Putative aminohydrolase SsnA CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 Pfam PF01979 Amidohydrolase family 56 412 8.4E-47 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 Gene3D G3DSA:3.20.20.140 71 371 5.2E-44 T 29-03-2018 CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 Gene3D G3DSA:2.30.40.10 372 442 1.0E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 Gene3D G3DSA:2.30.40.10 1 70 9.6E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 SUPERFAMILY SSF51338 1 59 2.88E-28 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS15970 5e5d8ef032b4f32d936c2717e7ee84a0 442 SUPERFAMILY SSF51338 364 439 2.88E-28 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 SUPERFAMILY SSF46785 6 143 1.29E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 SMART SM00347 23 127 2.8E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 Gene3D G3DSA:1.10.10.10 1 143 7.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 4.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 4.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS14440 75c5d644c913575292d6bcb35433b6a6 145 Pfam PF01047 MarR family 36 91 3.8E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS11465 e52cb78313c667521ca383cf2f93235f 116 Pfam PF12676 Protein of unknown function (DUF3796) 3 115 5.7E-39 T 29-03-2018 IPR024257 Protein of unknown function DUF3796 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 Gene3D G3DSA:1.20.1560.10 1 313 6.7E-69 T 29-03-2018 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 Pfam PF00664 ABC transporter transmembrane region 17 284 1.7E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 SUPERFAMILY SSF90123 3 314 4.19E-75 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 Gene3D G3DSA:3.40.50.300 335 580 1.8E-61 T 29-03-2018 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 SMART SM00382 365 558 3.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 Pfam PF00005 ABC transporter 356 504 1.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06930 87e1523d77311cf572516808b3f3ff5a 591 SUPERFAMILY SSF52540 332 583 3.13E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17005 f9a04fddbb8d50bf150f9c52850cc441 289 SUPERFAMILY SSF160964 8 35 4.58E-6 T 29-03-2018 CWR56_RS17005 f9a04fddbb8d50bf150f9c52850cc441 289 SUPERFAMILY SSF161098 50 275 1.28E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS17005 f9a04fddbb8d50bf150f9c52850cc441 289 Gene3D G3DSA:1.20.58.370 2 37 5.7E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CWR56_RS17005 f9a04fddbb8d50bf150f9c52850cc441 289 Gene3D G3DSA:1.10.3720.10 58 287 5.1E-44 T 29-03-2018 CWR56_RS17005 f9a04fddbb8d50bf150f9c52850cc441 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 283 2.0E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS10545 64b0e3d9758a7ab187ec0dc4a2535bc5 318 Gene3D G3DSA:2.60.40.740 22 172 1.2E-8 T 29-03-2018 CWR56_RS10545 64b0e3d9758a7ab187ec0dc4a2535bc5 318 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 28 80 6.7E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CWR56_RS17395 04839114e337c6da04ed40dd8c848645 321 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 265 1.3E-124 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CWR56_RS17395 04839114e337c6da04ed40dd8c848645 321 SUPERFAMILY SSF53448 3 269 5.01E-71 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS17395 04839114e337c6da04ed40dd8c848645 321 Gene3D G3DSA:3.90.550.10 2 292 5.2E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS17395 04839114e337c6da04ed40dd8c848645 321 Pfam PF00483 Nucleotidyl transferase 7 267 4.9E-35 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 SUPERFAMILY SSF53383 388 532 5.39E-46 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 SUPERFAMILY SSF53383 109 349 5.39E-46 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 16 537 3.5E-256 T 29-03-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 Pfam PF00155 Aminotransferase class I and II 193 522 6.3E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 Gene3D G3DSA:3.40.640.10 149 396 3.8E-22 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 323 336 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWR56_RS12705 a968bf3b4f3289df89521d4ec97e60c2 542 Gene3D G3DSA:3.90.1150.10 397 534 4.6E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS08725 b36299661f21c897ac87b8d3415084d3 323 Pfam PF07690 Major Facilitator Superfamily 140 308 2.9E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS08725 b36299661f21c897ac87b8d3415084d3 323 SUPERFAMILY SSF103473 2 313 1.31E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS08725 b36299661f21c897ac87b8d3415084d3 323 Gene3D G3DSA:1.20.1250.20 1 121 1.8E-17 T 29-03-2018 CWR56_RS08725 b36299661f21c897ac87b8d3415084d3 323 Gene3D G3DSA:1.20.1250.20 125 314 6.2E-25 T 29-03-2018 CWR56_RS09595 5bacf686657bb08e575a53e0c36c9252 270 Pfam PF00561 alpha/beta hydrolase fold 28 138 1.5E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS09595 5bacf686657bb08e575a53e0c36c9252 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 3.1E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS09595 5bacf686657bb08e575a53e0c36c9252 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.1E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS09595 5bacf686657bb08e575a53e0c36c9252 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 3.1E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS09595 5bacf686657bb08e575a53e0c36c9252 270 SUPERFAMILY SSF53474 12 270 2.8E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS09595 5bacf686657bb08e575a53e0c36c9252 270 Gene3D G3DSA:3.40.50.1820 11 270 2.3E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS16450 95b46600e3839499e9273c73fda13d83 71 Pfam PF09388 Spo0E like sporulation regulatory protein 27 67 7.0E-10 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CWR56_RS16450 95b46600e3839499e9273c73fda13d83 71 SUPERFAMILY SSF140500 23 69 8.11E-10 T 29-03-2018 CWR56_RS06270 cbc164b30c18a64d36029041b2907871 235 SMART SM00382 30 212 2.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS06270 cbc164b30c18a64d36029041b2907871 235 SUPERFAMILY SSF52540 4 215 3.07E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06270 cbc164b30c18a64d36029041b2907871 235 Pfam PF00005 ABC transporter 21 158 2.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06270 cbc164b30c18a64d36029041b2907871 235 Gene3D G3DSA:3.40.50.300 2 231 2.5E-60 T 29-03-2018 CWR56_RS06270 cbc164b30c18a64d36029041b2907871 235 TIGRFAM TIGR03740 galliderm_ABC: lantibiotic protection ABC transporter, ATP-binding subunit 6 227 2.9E-120 T 29-03-2018 IPR022501 Gallidermin ABC transporter, ATP-binding subunit CWR56_RS06270 cbc164b30c18a64d36029041b2907871 235 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 282 4.3E-96 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 PIRSF PIRSF001359 1 283 5.3E-104 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 SUPERFAMILY SSF51569 3 282 1.47E-97 T 29-03-2018 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 282 9.2E-100 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 Gene3D G3DSA:3.20.20.70 2 283 6.2E-102 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS17190 5f3719b57681a98f6ea3215ea111cd9e 283 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS11405 5761f8a950772754b6d680b61a00af9a 121 Pfam PF02498 BRO family, N-terminal domain 13 104 1.2E-18 T 29-03-2018 IPR003497 BRO N-terminal domain CWR56_RS11405 5761f8a950772754b6d680b61a00af9a 121 SMART SM01040 12 104 9.6E-25 T 29-03-2018 IPR003497 BRO N-terminal domain CWR56_RS01075 252d72803c4da2df9fd5f45c108fd2de 170 SUPERFAMILY SSF55469 2 165 1.07E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS01075 252d72803c4da2df9fd5f45c108fd2de 170 Pfam PF00881 Nitroreductase family 5 146 1.2E-22 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS01075 252d72803c4da2df9fd5f45c108fd2de 170 Gene3D G3DSA:3.40.109.10 1 169 1.3E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS03565 b4f0490765aa8cd3dfa0ddb3d861a1d6 116 ProDom PD053081 COIL MM0410 AF2262 COILED 61 113 5.0E-13 T 29-03-2018 CWR56_RS15340 57b93d02a00911723e23bc0a92656349 126 Gene3D G3DSA:3.30.460.10 1 107 1.2E-12 T 29-03-2018 CWR56_RS15340 57b93d02a00911723e23bc0a92656349 126 SUPERFAMILY SSF81301 3 107 1.05E-15 T 29-03-2018 CWR56_RS15340 57b93d02a00911723e23bc0a92656349 126 Pfam PF01909 Nucleotidyltransferase domain 21 57 7.8E-5 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CWR56_RS01545 53b13c4b085a0357f0b5a016b6004953 320 Gene3D G3DSA:3.40.50.2300 42 144 7.2E-22 T 29-03-2018 CWR56_RS01545 53b13c4b085a0357f0b5a016b6004953 320 SUPERFAMILY SSF53822 40 318 8.54E-73 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS01545 53b13c4b085a0357f0b5a016b6004953 320 Gene3D G3DSA:3.40.50.2300 145 320 4.4E-37 T 29-03-2018 CWR56_RS01545 53b13c4b085a0357f0b5a016b6004953 320 Pfam PF13407 Periplasmic binding protein domain 44 298 2.2E-51 T 29-03-2018 IPR025997 Periplasmic binding protein CWR56_RS01950 d8cab1bb0d706bece5b9a98f5ff5d97e 621 Pfam PF13245 AAA domain 22 263 6.2E-19 T 29-03-2018 CWR56_RS01950 d8cab1bb0d706bece5b9a98f5ff5d97e 621 Gene3D G3DSA:3.40.50.300 282 616 2.2E-28 T 29-03-2018 CWR56_RS01950 d8cab1bb0d706bece5b9a98f5ff5d97e 621 SUPERFAMILY SSF52540 168 590 8.42E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01950 d8cab1bb0d706bece5b9a98f5ff5d97e 621 SUPERFAMILY SSF52540 23 138 8.42E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01950 d8cab1bb0d706bece5b9a98f5ff5d97e 621 Gene3D G3DSA:3.40.50.300 20 281 1.3E-35 T 29-03-2018 CWR56_RS01950 d8cab1bb0d706bece5b9a98f5ff5d97e 621 Pfam PF13361 UvrD-like helicase C-terminal domain 287 585 2.0E-24 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 PRINTS PR00175 Sodium/alanine symporter signature 204 223 5.4E-42 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 PRINTS PR00175 Sodium/alanine symporter signature 176 194 5.4E-42 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 PRINTS PR00175 Sodium/alanine symporter signature 86 108 5.4E-42 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 PRINTS PR00175 Sodium/alanine symporter signature 295 313 5.4E-42 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 PRINTS PR00175 Sodium/alanine symporter signature 348 370 5.4E-42 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 PRINTS PR00175 Sodium/alanine symporter signature 415 435 5.4E-42 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 Pfam PF01235 Sodium:alanine symporter family 52 454 1.7E-136 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS12225 0fafb416e3246b9886b8a6b8477e4269 487 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 446 2.7E-121 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR56_RS17200 dcc9b2c19bcd38ac777cb049d1dd8ab6 305 Gene3D G3DSA:3.40.50.720 1 128 6.2E-30 T 29-03-2018 CWR56_RS17200 dcc9b2c19bcd38ac777cb049d1dd8ab6 305 SUPERFAMILY SSF55347 126 265 9.81E-29 T 29-03-2018 CWR56_RS17200 dcc9b2c19bcd38ac777cb049d1dd8ab6 305 Gene3D G3DSA:3.30.360.10 129 305 3.1E-12 T 29-03-2018 CWR56_RS17200 dcc9b2c19bcd38ac777cb049d1dd8ab6 305 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 2.1E-22 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CWR56_RS17200 dcc9b2c19bcd38ac777cb049d1dd8ab6 305 SUPERFAMILY SSF51735 4 137 1.7E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS16050 c30b2e6a908b36b0babc2d8bc0ac43ce 320 Pfam PF00144 Beta-lactamase 23 299 7.3E-28 T 29-03-2018 IPR001466 Beta-lactamase-related CWR56_RS16050 c30b2e6a908b36b0babc2d8bc0ac43ce 320 SUPERFAMILY SSF56601 16 316 2.18E-73 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR56_RS16050 c30b2e6a908b36b0babc2d8bc0ac43ce 320 Gene3D G3DSA:3.40.710.10 1 319 2.4E-54 T 29-03-2018 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Gene3D G3DSA:3.40.930.10 518 691 7.7E-11 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Pfam PF05043 Mga helix-turn-helix domain 90 172 6.8E-5 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Pfam PF08279 HTH domain 9 68 2.9E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Gene3D G3DSA:1.10.1790.10 159 312 9.7E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 SUPERFAMILY SSF63520 205 312 1.57E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 434 491 5.1E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Gene3D G3DSA:1.10.10.10 92 158 8.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Gene3D G3DSA:1.10.10.10 2 73 1.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 SUPERFAMILY SSF63520 320 426 6.67E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 SUPERFAMILY SSF55804 590 677 5.41E-6 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Pfam PF00874 PRD domain 228 307 6.0E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Pfam PF00874 PRD domain 332 422 5.5E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 SUPERFAMILY SSF52794 433 520 6.8E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Gene3D G3DSA:1.10.1790.10 321 426 1.3E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 CWR56_RS11595 3f28c2b325f91a5a307ac50f2474bd16 709 Gene3D G3DSA:3.40.50.2300 430 517 1.0E-18 T 29-03-2018 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 SUPERFAMILY SSF52540 295 743 3.19E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Gene3D G3DSA:3.40.50.300 261 688 2.3E-27 T 29-03-2018 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1152 0.0 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1155 63.156 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Gene3D G3DSA:3.40.50.300 131 260 2.2E-27 T 29-03-2018 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Gene3D G3DSA:3.40.50.300 1 130 1.1E-23 T 29-03-2018 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 310 430 1.3E-8 T 29-03-2018 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Pfam PF12705 PD-(D/E)XK nuclease superfamily 781 1125 1.2E-55 T 29-03-2018 CWR56_RS04770 8ab5cf4974e41a37ce25bf6cd5be5d98 1155 Gene3D G3DSA:3.90.320.10 748 988 5.5E-13 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 77 1.8E-36 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 15 77 6.0E-23 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 2.1E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 2.1E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 2.1E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 SUPERFAMILY SSF50249 5 83 7.28E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 Gene3D G3DSA:2.40.50.140 6 83 9.1E-31 T 29-03-2018 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 81 25.305 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00130 50847316318b3a5ef3a679550164484e 84 Pfam PF00366 Ribosomal protein S17 11 78 1.4E-34 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 Gene3D G3DSA:1.10.10.60 9 66 2.2E-15 T 29-03-2018 CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 SUPERFAMILY SSF48498 86 197 2.0E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 Gene3D G3DSA:1.10.357.10 67 197 3.2E-19 T 29-03-2018 CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 2.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS02690 5f6675cd704f4d969e352e342298bd1e 201 SUPERFAMILY SSF46689 9 90 1.57E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS11410 31e4e3e594a332d20c173fd3ad93979f 307 Pfam PF09851 Short C-terminal domain 279 306 6.5E-11 T 29-03-2018 IPR018649 SHOCT domain CWR56_RS06530 50381856c23beea9ad1990194c1b833b 158 Gene3D G3DSA:2.40.30.70 7 142 3.4E-32 T 29-03-2018 IPR023370 TsaA-like domain CWR56_RS06530 50381856c23beea9ad1990194c1b833b 158 Pfam PF01980 Uncharacterised protein family UPF0066 15 126 1.5E-27 T 29-03-2018 IPR023370 TsaA-like domain CWR56_RS06530 50381856c23beea9ad1990194c1b833b 158 SUPERFAMILY SSF118196 1 154 2.09E-42 T 29-03-2018 IPR023370 TsaA-like domain CWR56_RS08030 33f81d3772797c49de8aa1c26c2cb8f8 134 Pfam PF04205 FMN-binding domain 67 130 2.1E-11 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CWR56_RS08030 33f81d3772797c49de8aa1c26c2cb8f8 134 SMART SM00900 60 133 6.8E-11 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CWR56_RS13675 1b923da32155b1e8b9593ba9d25b1820 427 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 12 409 1.3E-91 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR56_RS13675 1b923da32155b1e8b9593ba9d25b1820 427 Pfam PF05525 Branched-chain amino acid transport protein 5 423 4.8E-107 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR56_RS16920 383814c9d72145ab76c77a214b4f221a 372 SUPERFAMILY SSF142338 47 361 5.75E-98 T 29-03-2018 CWR56_RS16920 383814c9d72145ab76c77a214b4f221a 372 Gene3D G3DSA:3.40.50.10680 125 371 1.5E-57 T 29-03-2018 CWR56_RS16920 383814c9d72145ab76c77a214b4f221a 372 Hamap MF_00973 Gluconeogenesis factor. 46 366 33.68 T 29-03-2018 IPR010119 Gluconeogenesis factor CWR56_RS16920 383814c9d72145ab76c77a214b4f221a 372 Pfam PF01933 Uncharacterised protein family UPF0052 50 341 1.9E-105 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CWR56_RS16920 383814c9d72145ab76c77a214b4f221a 372 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 50 363 4.1E-113 T 29-03-2018 IPR010119 Gluconeogenesis factor CWR56_RS06365 9985f709fe16186e93665acfd8821d8e 817 Gene3D G3DSA:1.20.5.1230 19 282 7.1E-6 T 29-03-2018 CWR56_RS06365 9985f709fe16186e93665acfd8821d8e 817 Gene3D G3DSA:1.20.5.1230 491 711 2.0E-5 T 29-03-2018 CWR56_RS06365 9985f709fe16186e93665acfd8821d8e 817 Gene3D G3DSA:1.20.5.1230 303 490 0.0031 T 29-03-2018 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 377 4.2E-8 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Pfam PF00623 RNA polymerase Rpb1, domain 2 381 474 2.9E-28 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Gene3D G3DSA:2.40.50.100 882 999 2.5E-43 T 29-03-2018 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1160 18.474 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 SUPERFAMILY SSF64484 5 1152 0.0 T 29-03-2018 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 9 1152 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Pfam PF05000 RNA polymerase Rpb1, domain 4 664 726 2.9E-13 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Pfam PF04998 RNA polymerase Rpb1, domain 5 742 1100 3.2E-67 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 635 3.3E-25 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Gene3D G3DSA:2.40.40.20 335 477 3.2E-39 T 29-03-2018 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 331 1.6E-91 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS00055 7494effba9b2e3526a1d1dccae7f2034 1161 SMART SM00663 224 503 1.3E-182 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR56_RS03870 2918be56dd41c83e5959cf602e9c1aab 125 Pfam PF01925 Sulfite exporter TauE/SafE 4 109 7.9E-22 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 Gene3D G3DSA:1.20.1560.10 4 330 2.0E-48 T 29-03-2018 CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 SUPERFAMILY SSF52540 339 575 2.61E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 SUPERFAMILY SSF90123 18 324 6.28E-55 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 Gene3D G3DSA:3.40.50.300 339 574 9.4E-72 T 29-03-2018 CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 SMART SM00382 368 559 6.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 Pfam PF00005 ABC transporter 359 507 5.3E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS02350 e1c40233cbe4d45740379816f03e4c98 580 Pfam PF00664 ABC transporter transmembrane region 24 294 2.0E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR56_RS02125 8d9281a4dfce3b252eead6edb00c0a81 201 SUPERFAMILY SSF56281 2 198 2.23E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02125 8d9281a4dfce3b252eead6edb00c0a81 201 SMART SM00849 15 195 3.0E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02125 8d9281a4dfce3b252eead6edb00c0a81 201 Pfam PF00753 Metallo-beta-lactamase superfamily 14 195 1.2E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02125 8d9281a4dfce3b252eead6edb00c0a81 201 Gene3D G3DSA:3.60.15.10 1 200 1.0E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS16135 d12266ef6aa5e9c3e95b27114606d03f 259 Pfam PF13847 Methyltransferase domain 53 165 5.9E-12 T 29-03-2018 IPR025714 Methyltransferase domain CWR56_RS16135 d12266ef6aa5e9c3e95b27114606d03f 259 Gene3D G3DSA:3.40.50.150 27 241 3.4E-18 T 29-03-2018 CWR56_RS16135 d12266ef6aa5e9c3e95b27114606d03f 259 SUPERFAMILY SSF53335 35 199 5.23E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 SUPERFAMILY SSF161098 23 279 7.96E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 387 566 4.0E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 278 3.8E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 SUPERFAMILY SSF161098 309 560 7.98E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 Gene3D G3DSA:1.10.3720.10 23 283 1.4E-40 T 29-03-2018 CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 Gene3D G3DSA:1.10.3720.10 302 571 5.6E-24 T 29-03-2018 CWR56_RS14675 80194b87bd2465dc84a5606e02b9f60b 572 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 22 570 2.2E-202 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 SUPERFAMILY SSF51338 5 60 1.42E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 SUPERFAMILY SSF51338 490 532 1.42E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 Gene3D G3DSA:2.30.40.10 3 113 3.7E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 Gene3D G3DSA:3.20.20.140 183 488 1.6E-37 T 29-03-2018 CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 Pfam PF07969 Amidohydrolase family 48 531 2.5E-94 T 29-03-2018 IPR013108 Amidohydrolase 3 CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 SUPERFAMILY SSF51556 190 491 7.49E-20 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS14425 870e52329456a143fc161a17ecb15891 534 SUPERFAMILY SSF51556 59 80 7.49E-20 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS04285 974551c1442f127647166128657b672a 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 129 164 1.2E-10 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS04285 974551c1442f127647166128657b672a 185 SMART SM01266 4 58 6.4E-22 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWR56_RS04285 974551c1442f127647166128657b672a 185 Gene3D G3DSA:2.160.10.10 1 185 5.6E-54 T 29-03-2018 CWR56_RS04285 974551c1442f127647166128657b672a 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 138 166 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR56_RS04285 974551c1442f127647166128657b672a 185 Pfam PF12464 Maltose acetyltransferase 6 57 7.0E-17 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWR56_RS04285 974551c1442f127647166128657b672a 185 SUPERFAMILY SSF51161 2 183 1.05E-55 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS04675 ecf99851919de7457429993ea6712d39 278 SUPERFAMILY SSF161098 3 265 5.1E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04675 ecf99851919de7457429993ea6712d39 278 Gene3D G3DSA:1.10.3720.10 5 273 3.4E-45 T 29-03-2018 CWR56_RS04675 ecf99851919de7457429993ea6712d39 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 264 3.1E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS03640 2b6edddc72186cd540676b4ebefbc267 271 SUPERFAMILY SSF53850 5 262 5.29E-57 T 29-03-2018 CWR56_RS03640 2b6edddc72186cd540676b4ebefbc267 271 Gene3D G3DSA:3.40.190.10 144 224 2.4E-14 T 29-03-2018 CWR56_RS03640 2b6edddc72186cd540676b4ebefbc267 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 261 3.4E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS03640 2b6edddc72186cd540676b4ebefbc267 271 Gene3D G3DSA:3.40.190.10 30 143 9.0E-33 T 29-03-2018 CWR56_RS03640 2b6edddc72186cd540676b4ebefbc267 271 SMART SM00062 40 264 9.1E-45 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS02935 7cd07db61e473d3218d65f91b9207f53 85 SUPERFAMILY SSF46689 4 83 6.27E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02935 7cd07db61e473d3218d65f91b9207f53 85 Pfam PF08765 Mor transcription activator family 13 82 1.1E-13 T 29-03-2018 IPR014875 Mor transcription activator CWR56_RS02935 7cd07db61e473d3218d65f91b9207f53 85 Gene3D G3DSA:1.10.10.60 43 85 1.6E-10 T 29-03-2018 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 Gene3D G3DSA:3.90.79.10 2 155 4.0E-24 T 29-03-2018 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 SUPERFAMILY SSF55811 3 134 2.03E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 PRINTS PR01402 Mutator MutX protein signature 3 21 5.1E-26 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 PRINTS PR01402 Mutator MutX protein signature 67 93 5.1E-26 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 PRINTS PR01402 Mutator MutX protein signature 138 158 5.1E-26 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 PRINTS PR01402 Mutator MutX protein signature 21 36 5.1E-26 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 Pfam PF00293 NUDIX domain 7 131 3.3E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 PRINTS PR00502 NUDIX hydrolase family signature 46 61 5.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 PRINTS PR00502 NUDIX hydrolase family signature 32 46 5.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR56_RS03390 af182b55d9f7374beeee524b8b0fcb30 158 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR56_RS10890 6670db84dc6501eab3fc4d45a962124d 273 SUPERFAMILY SSF52540 14 242 1.05E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10890 6670db84dc6501eab3fc4d45a962124d 273 Gene3D G3DSA:3.40.50.300 2 217 9.4E-31 T 29-03-2018 CWR56_RS10890 6670db84dc6501eab3fc4d45a962124d 273 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 35 178 1.1E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR56_RS10890 6670db84dc6501eab3fc4d45a962124d 273 SMART SM00382 31 189 2.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 Gene3D G3DSA:2.70.70.10 522 683 7.2E-54 T 29-03-2018 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 Gene3D G3DSA:3.30.1360.60 425 500 2.4E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 535 659 1.8E-48 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 SUPERFAMILY SSF55604 427 500 6.41E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 538 657 3.6E-42 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 SUPERFAMILY SSF51261 534 676 2.44E-49 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 Pfam PF02378 Phosphotransferase system, EIIC 12 341 2.2E-88 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 1 502 2.0E-238 T 29-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 440 457 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 Pfam PF00367 phosphotransferase system, EIIB 430 462 2.7E-12 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 400 486 3.8E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS13490 e5edfdb60c010833d9962f948647cd87 690 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 599 611 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS14775 265b956d4f8d85d80f3aec04472804e9 463 Gene3D G3DSA:3.40.50.980 1 156 1.7E-6 T 29-03-2018 CWR56_RS14775 265b956d4f8d85d80f3aec04472804e9 463 Gene3D G3DSA:3.30.300.30 365 463 3.4E-18 T 29-03-2018 CWR56_RS14775 265b956d4f8d85d80f3aec04472804e9 463 Pfam PF00501 AMP-binding enzyme 11 327 5.5E-21 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR56_RS14775 265b956d4f8d85d80f3aec04472804e9 463 SUPERFAMILY SSF56801 2 462 3.4E-63 T 29-03-2018 CWR56_RS14775 265b956d4f8d85d80f3aec04472804e9 463 Gene3D G3DSA:3.40.50.980 157 319 2.3E-18 T 29-03-2018 CWR56_RS14775 265b956d4f8d85d80f3aec04472804e9 463 Pfam PF13193 AMP-binding enzyme C-terminal domain 380 453 4.2E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR56_RS12565 774f8a956b0e306c28549d22e64105ed 420 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 36 399 3.0E-49 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS12565 774f8a956b0e306c28549d22e64105ed 420 Pfam PF02378 Phosphotransferase system, EIIC 47 352 6.0E-11 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS01385 366e8875d95ca72f45fdafa6b46a92c5 293 Pfam PF02154 Flagellar motor switch protein FliM 7 193 2.5E-16 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CWR56_RS01385 366e8875d95ca72f45fdafa6b46a92c5 293 SUPERFAMILY SSF101801 216 290 2.22E-13 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01385 366e8875d95ca72f45fdafa6b46a92c5 293 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 219 288 5.5E-16 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS01385 366e8875d95ca72f45fdafa6b46a92c5 293 Gene3D G3DSA:3.40.1550.10 16 202 8.6E-12 T 29-03-2018 IPR028976 CheC-like domain CWR56_RS01385 366e8875d95ca72f45fdafa6b46a92c5 293 Gene3D G3DSA:2.30.330.10 206 293 1.3E-14 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CWR56_RS18375 67d5a9eba5ac6ae930836b5be5a522b2 191 Pfam PF10646 Sporulation and spore germination 75 177 1.4E-7 T 29-03-2018 IPR019606 GerMN domain CWR56_RS18375 67d5a9eba5ac6ae930836b5be5a522b2 191 SMART SM00909 97 181 1.8E-10 T 29-03-2018 IPR019606 GerMN domain CWR56_RS18375 67d5a9eba5ac6ae930836b5be5a522b2 191 Gene3D G3DSA:3.40.190.10 1 187 1.5E-4 T 29-03-2018 CWR56_RS09100 213f2813e4d97e56bdafa77ef5d2cdd8 489 SUPERFAMILY SSF53720 10 452 1.44E-80 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR56_RS09100 213f2813e4d97e56bdafa77ef5d2cdd8 489 Pfam PF00171 Aldehyde dehydrogenase family 12 274 7.2E-26 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS09100 213f2813e4d97e56bdafa77ef5d2cdd8 489 Gene3D G3DSA:3.40.309.10 235 408 7.6E-23 T 29-03-2018 CWR56_RS09100 213f2813e4d97e56bdafa77ef5d2cdd8 489 TIGRFAM TIGR02518 EutH_ACDH: acetaldehyde dehydrogenase (acetylating) 5 488 3.6E-241 T 29-03-2018 IPR013357 Acetaldehyde dehydrogenase, acetylating CWR56_RS09100 213f2813e4d97e56bdafa77ef5d2cdd8 489 Gene3D G3DSA:3.40.605.10 7 234 5.2E-31 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 Gene3D G3DSA:3.30.565.10 239 379 5.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 376 5.3E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 224 4.5E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 SUPERFAMILY SSF47384 143 225 8.04E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 SMART SM00388 157 227 1.3E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 SMART SM00387 271 380 4.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 Gene3D G3DSA:1.10.287.130 140 228 6.3E-8 T 29-03-2018 CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 SUPERFAMILY SSF158472 101 145 3.92E-7 T 29-03-2018 CWR56_RS02240 bcf42986f93c6679f5c545b83d9e0ad0 380 SUPERFAMILY SSF55874 234 373 1.57E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS14905 17dcd059ca9b9bc481ebd9f40085d8ad 241 Pfam PF13599 Pentapeptide repeats (9 copies) 55 123 3.8E-10 T 29-03-2018 IPR001646 Pentapeptide repeat CWR56_RS14905 17dcd059ca9b9bc481ebd9f40085d8ad 241 Gene3D G3DSA:2.160.20.80 2 146 1.1E-24 T 29-03-2018 CWR56_RS14905 17dcd059ca9b9bc481ebd9f40085d8ad 241 SUPERFAMILY SSF141571 28 124 7.98E-22 T 29-03-2018 CWR56_RS16220 4f8137eda0bf7cc4ce7633569b755ebd 329 SMART SM00244 70 262 3.2E-12 T 29-03-2018 IPR001107 Band 7 domain CWR56_RS16220 4f8137eda0bf7cc4ce7633569b755ebd 329 SUPERFAMILY SSF117892 135 265 8.63E-13 T 29-03-2018 IPR001107 Band 7 domain CWR56_RS16220 4f8137eda0bf7cc4ce7633569b755ebd 329 Pfam PF01145 SPFH domain / Band 7 family 74 275 1.2E-28 T 29-03-2018 IPR001107 Band 7 domain CWR56_RS15665 797a49bf5e17e012881eabd72a3253dd 292 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 283 6.2E-83 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS15665 797a49bf5e17e012881eabd72a3253dd 292 Gene3D G3DSA:3.20.20.70 3 291 1.2E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS15665 797a49bf5e17e012881eabd72a3253dd 292 PIRSF PIRSF001359 1 284 3.6E-94 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS15665 797a49bf5e17e012881eabd72a3253dd 292 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 282 2.4E-90 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR56_RS15665 797a49bf5e17e012881eabd72a3253dd 292 SUPERFAMILY SSF51569 4 283 4.4E-89 T 29-03-2018 CWR56_RS06700 711410c97141565b669fb7f1006776d1 184 Gene3D G3DSA:3.40.50.850 1 181 5.4E-42 T 29-03-2018 CWR56_RS06700 711410c97141565b669fb7f1006776d1 184 Pfam PF00857 Isochorismatase family 4 175 2.0E-35 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWR56_RS06700 711410c97141565b669fb7f1006776d1 184 SUPERFAMILY SSF52499 3 181 1.44E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWR56_RS02660 74d6fb14d2521e68246f3359997f5205 446 SUPERFAMILY SSF55874 332 435 5.24E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02660 74d6fb14d2521e68246f3359997f5205 446 Gene3D G3DSA:3.30.565.10 297 440 5.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02660 74d6fb14d2521e68246f3359997f5205 446 Pfam PF14501 GHKL domain 334 434 3.7E-25 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS02660 74d6fb14d2521e68246f3359997f5205 446 Gene3D G3DSA:1.10.287.130 231 293 1.8E-6 T 29-03-2018 CWR56_RS07110 6669089a4d734ab994c7c8c3135adf49 194 SUPERFAMILY SSF52833 1 186 1.15E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS07110 6669089a4d734ab994c7c8c3135adf49 194 Gene3D G3DSA:3.40.30.10 19 194 5.3E-23 T 29-03-2018 CWR56_RS07110 6669089a4d734ab994c7c8c3135adf49 194 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWR56_RS07110 6669089a4d734ab994c7c8c3135adf49 194 Pfam PF08534 Redoxin 45 173 1.4E-9 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CWR56_RS06990 7d3f80a861f48811c0e5be18057148a1 330 SMART SM00062 45 260 3.6E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR56_RS06990 7d3f80a861f48811c0e5be18057148a1 330 Gene3D G3DSA:3.40.190.10 159 330 2.1E-33 T 29-03-2018 CWR56_RS06990 7d3f80a861f48811c0e5be18057148a1 330 Gene3D G3DSA:3.40.190.10 65 158 1.7E-8 T 29-03-2018 CWR56_RS06990 7d3f80a861f48811c0e5be18057148a1 330 SUPERFAMILY SSF53850 46 325 2.66E-42 T 29-03-2018 CWR56_RS06990 7d3f80a861f48811c0e5be18057148a1 330 Pfam PF09084 NMT1/THI5 like 72 266 2.2E-20 T 29-03-2018 IPR015168 SsuA/THI5-like CWR56_RS06990 7d3f80a861f48811c0e5be18057148a1 330 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 49 328 8.5E-55 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 Pfam PF00391 PEP-utilising enzyme, mobile domain 778 849 3.7E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 SUPERFAMILY SSF56059 9 342 1.77E-97 T 29-03-2018 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 Gene3D G3DSA:3.50.30.10 742 853 2.8E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 314 2.1E-109 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 SUPERFAMILY SSF52009 745 854 5.76E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 Gene3D G3DSA:3.30.470.20 183 329 2.4E-42 T 29-03-2018 CWR56_RS02695 8b779719903deda80e0f6e7f87686710 855 Gene3D G3DSA:3.30.1490.20 2 181 1.3E-53 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR56_RS08545 fb5c47d828cff985dc9a0e27a5421ba6 203 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 2 95 1.7E-25 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWR56_RS08545 fb5c47d828cff985dc9a0e27a5421ba6 203 Gene3D G3DSA:1.10.3720.10 1 203 8.9E-37 T 29-03-2018 CWR56_RS08545 fb5c47d828cff985dc9a0e27a5421ba6 203 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 20 198 4.2E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS08545 fb5c47d828cff985dc9a0e27a5421ba6 203 SUPERFAMILY SSF161098 3 192 2.22E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS02785 da30e7abb835f55c86e0ccadfc0d220a 87 PIRSF PIRSF010606 1 83 1.1E-26 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB CWR56_RS02785 da30e7abb835f55c86e0ccadfc0d220a 87 Pfam PF12652 CotJB protein 7 82 2.1E-28 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain CWR56_RS01900 0c917e7c1a45f514dc74eca5d412df0a 375 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 36 372 3.6E-61 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit CWR56_RS07445 a6beef470e8b4683643ce67b2d5d6106 311 Pfam PF12146 Serine aminopeptidase, S33 28 291 3.5E-59 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CWR56_RS07445 a6beef470e8b4683643ce67b2d5d6106 311 SUPERFAMILY SSF53474 3 307 7.01E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS07445 a6beef470e8b4683643ce67b2d5d6106 311 Gene3D G3DSA:3.40.50.1820 2 309 1.5E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS16280 97dbdd89748ecaa7e71b58e406112535 155 Gene3D G3DSA:3.40.50.40 19 154 0.0027 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CWR56_RS16280 97dbdd89748ecaa7e71b58e406112535 155 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 5 125 1.3E-10 T 29-03-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CWR56_RS01245 990dd9f11adb43e207ed931aac2ceff8 363 PIRSF PIRSF000390 3 363 1.2E-102 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CWR56_RS01245 990dd9f11adb43e207ed931aac2ceff8 363 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 360 6.3E-115 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CWR56_RS01245 990dd9f11adb43e207ed931aac2ceff8 363 Gene3D G3DSA:3.90.1150.10 238 363 1.3E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS01245 990dd9f11adb43e207ed931aac2ceff8 363 SUPERFAMILY SSF53383 13 363 1.09E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS01245 990dd9f11adb43e207ed931aac2ceff8 363 Gene3D G3DSA:3.40.640.10 2 237 3.6E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS04965 23aa38c574aa2900f588ff67a173dcb3 137 SUPERFAMILY SSF53062 1 130 1.26E-29 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS04965 23aa38c574aa2900f588ff67a173dcb3 137 Gene3D G3DSA:3.40.50.510 1 136 8.1E-27 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS04965 23aa38c574aa2900f588ff67a173dcb3 137 Pfam PF03610 PTS system fructose IIA component 3 111 2.3E-17 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01875 833981522c5a55300563e66f1bb446c5 175 Pfam PF07155 ECF-type riboflavin transporter, S component 11 164 1.5E-15 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CWR56_RS01875 833981522c5a55300563e66f1bb446c5 175 TIGRFAM TIGR04002 TIGR04002: TIGR04002 family protein 21 171 8.6E-73 T 29-03-2018 IPR023812 Conserved hypothetical protein CHP04002 CWR56_RS15765 b1d43edaa0976ad9431784be4b84154a 473 TIGRFAM TIGR03236 dnd_assoc_1: DNA phosphorothioation-dependent restriction protein DptG 103 473 3.1E-59 T 29-03-2018 IPR017645 DNA phosphorothioation-dependent restriction protein DptG CWR56_RS00590 da9727f7097cced24062d07709f17d3e 354 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 18 352 1.5E-104 T 29-03-2018 IPR014225 Sporulation stage II, protein D firmicutes CWR56_RS00590 da9727f7097cced24062d07709f17d3e 354 Pfam PF08486 Stage II sporulation protein 82 185 3.9E-25 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CWR56_RS00590 da9727f7097cced24062d07709f17d3e 354 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 86 351 3.7E-71 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CWR56_RS04145 f8ffa5ba10f09ccaf7e1409d3a6c0dde 154 SUPERFAMILY SSF47413 1 68 2.82E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS04145 f8ffa5ba10f09ccaf7e1409d3a6c0dde 154 Gene3D G3DSA:3.30.1190.10 26 92 1.4E-21 T 29-03-2018 CWR56_RS04145 f8ffa5ba10f09ccaf7e1409d3a6c0dde 154 SMART SM00530 6 61 5.8E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS04145 f8ffa5ba10f09ccaf7e1409d3a6c0dde 154 Gene3D G3DSA:1.10.10.10 3 25 2.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04145 f8ffa5ba10f09ccaf7e1409d3a6c0dde 154 Pfam PF01381 Helix-turn-helix 9 61 4.4E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS13175 3f72d08d970186873d486958b1b6224b 73 SUPERFAMILY SSF56988 1 73 2.75E-26 T 29-03-2018 CWR56_RS13175 3f72d08d970186873d486958b1b6224b 73 Gene3D G3DSA:2.60.120.240 1 73 4.9E-29 T 29-03-2018 IPR027439 Protective antigen, heptamerisation domain GO:0051260 CWR56_RS13175 3f72d08d970186873d486958b1b6224b 73 PRINTS PR01391 Binary toxin B family signature 29 48 1.3E-16 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CWR56_RS13175 3f72d08d970186873d486958b1b6224b 73 PRINTS PR01391 Binary toxin B family signature 54 72 1.3E-16 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CWR56_RS13175 3f72d08d970186873d486958b1b6224b 73 Pfam PF17475 Clostridial binary toxin B/anthrax toxin PA domain 2 1 73 1.9E-19 T 29-03-2018 IPR027439 Protective antigen, heptamerisation domain GO:0051260 CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 Pfam PF13545 Crp-like helix-turn-helix domain 157 222 8.5E-18 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 SMART SM00419 170 216 4.4E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 SUPERFAMILY SSF51206 13 152 3.27E-28 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 Pfam PF00027 Cyclic nucleotide-binding domain 36 121 3.2E-7 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 Gene3D G3DSA:1.10.10.10 153 225 8.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 Gene3D G3DSA:2.60.120.10 5 152 3.3E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 SUPERFAMILY SSF46785 154 223 8.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 190 205 4.7E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS02965 f00c2538dea5a61cc5250b0ad7525858 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 174 190 4.7E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWR56_RS04575 ae19b0783158b08a04f329493725fcd0 129 SUPERFAMILY SSF55729 15 115 2.66E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS04575 ae19b0783158b08a04f329493725fcd0 129 Pfam PF13673 Acetyltransferase (GNAT) domain 39 117 3.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS04575 ae19b0783158b08a04f329493725fcd0 129 Gene3D G3DSA:3.40.630.30 4 122 2.6E-12 T 29-03-2018 CWR56_RS11590 0f82d0274239364fb38987d29abc7864 140 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 48 64 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS11590 0f82d0274239364fb38987d29abc7864 140 SUPERFAMILY SSF55804 3 139 8.76E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11590 0f82d0274239364fb38987d29abc7864 140 Gene3D G3DSA:3.40.930.10 1 140 1.2E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS11590 0f82d0274239364fb38987d29abc7864 140 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 139 1.1E-32 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15235 39d8cd44a2a6b129ee9a617f3df5615a 250 Gene3D G3DSA:3.40.50.300 1 237 2.6E-65 T 29-03-2018 CWR56_RS15235 39d8cd44a2a6b129ee9a617f3df5615a 250 SMART SM00382 33 221 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15235 39d8cd44a2a6b129ee9a617f3df5615a 250 Pfam PF00005 ABC transporter 24 172 5.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS15235 39d8cd44a2a6b129ee9a617f3df5615a 250 SUPERFAMILY SSF52540 4 223 4.09E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09475 dad28e71802aa76e1890e14f81a73174 490 Pfam PF04122 Putative cell wall binding repeat 2 230 298 4.5E-7 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS09475 dad28e71802aa76e1890e14f81a73174 490 Pfam PF04122 Putative cell wall binding repeat 2 140 221 8.0E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS09475 dad28e71802aa76e1890e14f81a73174 490 Pfam PF04122 Putative cell wall binding repeat 2 33 128 5.3E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS00610 2291be5ec959e286e7289da6538f9f21 142 Pfam PF07977 FabA-like domain 11 133 2.0E-34 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR56_RS00610 2291be5ec959e286e7289da6538f9f21 142 SUPERFAMILY SSF54637 1 138 3.14E-50 T 29-03-2018 IPR029069 HotDog domain CWR56_RS00610 2291be5ec959e286e7289da6538f9f21 142 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 6.9E-58 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR56_RS00610 2291be5ec959e286e7289da6538f9f21 142 Gene3D G3DSA:3.10.129.10 2 142 2.3E-55 T 29-03-2018 CWR56_RS00610 2291be5ec959e286e7289da6538f9f21 142 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 33.488 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 Gene3D G3DSA:3.40.640.10 120 368 4.3E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 SUPERFAMILY SSF53383 76 466 7.0E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 Gene3D G3DSA:3.90.1150.10 369 468 1.3E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 81 4.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 Pfam PF00155 Aminotransferase class I and II 105 458 1.4E-30 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 Gene3D G3DSA:1.10.10.10 5 83 9.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 SUPERFAMILY SSF46785 15 91 1.98E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04945 e9699f3abe37ea9458688eb3f09a9fa8 484 SMART SM00345 22 81 7.2E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS04305 e297994fc1bbafcd0defabf38f37176a 345 Gene3D G3DSA:3.40.50.2300 166 311 1.2E-21 T 29-03-2018 CWR56_RS04305 e297994fc1bbafcd0defabf38f37176a 345 Gene3D G3DSA:3.40.50.2300 43 165 1.7E-22 T 29-03-2018 CWR56_RS04305 e297994fc1bbafcd0defabf38f37176a 345 SUPERFAMILY SSF53822 62 234 3.4E-12 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS04305 e297994fc1bbafcd0defabf38f37176a 345 Pfam PF04392 ABC transporter substrate binding protein 47 325 1.4E-94 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 Pfam PF01022 Bacterial regulatory protein, arsR family 13 57 6.9E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 4.1E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 4.1E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 4.1E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 Gene3D G3DSA:1.10.10.10 5 70 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 SMART SM00418 6 84 2.8E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS09540 19d0584de188933b41e5173127f5bd79 98 SUPERFAMILY SSF46785 5 85 2.05E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17905 2238f62045b2297196bbfea126ffda92 228 Gene3D G3DSA:3.40.50.300 1 226 9.8E-64 T 29-03-2018 CWR56_RS17905 2238f62045b2297196bbfea126ffda92 228 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS17905 2238f62045b2297196bbfea126ffda92 228 SMART SM00382 32 218 1.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17905 2238f62045b2297196bbfea126ffda92 228 Pfam PF00005 ABC transporter 23 169 1.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS17905 2238f62045b2297196bbfea126ffda92 228 SUPERFAMILY SSF52540 4 223 2.35E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 Pfam PF01545 Cation efflux family 21 213 1.2E-50 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 SUPERFAMILY SSF161111 13 216 8.24E-57 T 29-03-2018 CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 Gene3D G3DSA:3.30.70.1350 214 299 1.0E-16 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 Gene3D G3DSA:1.20.1510.10 16 213 1.2E-49 T 29-03-2018 CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 297 1.9E-71 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 SUPERFAMILY SSF160240 218 295 6.15E-17 T 29-03-2018 CWR56_RS10940 4723aa6b4eb8266151a5118da5043c9d 303 Pfam PF16916 Dimerisation domain of Zinc Transporter 220 295 3.8E-23 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 SUPERFAMILY SSF46557 6 79 1.57E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 Gene3D G3DSA:3.10.50.30 79 159 1.5E-25 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 30.93 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 PIRSF PIRSF006092 1 159 1.3E-49 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 158 1.7E-25 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 SUPERFAMILY SSF54534 85 158 9.16E-21 T 29-03-2018 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 9 157 1.2E-54 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 Gene3D G3DSA:1.10.287.180 6 78 1.4E-29 T 29-03-2018 CWR56_RS17740 22b51e5b53f26c1b6d5fda5d20d20b44 159 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.3E-29 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CWR56_RS06770 50267f4391496722bb1893ff4dc3289c 229 Pfam PF04172 LrgB-like family 15 227 1.9E-73 T 29-03-2018 IPR007300 CidB/LrgB family CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 Pfam PF02867 Ribonucleotide reductase, barrel domain 163 641 8.1E-127 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 83 649 1.7E-152 T 29-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 PRINTS PR01183 Ribonucleotide reductase large chain signature 509 536 4.5E-31 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 PRINTS PR01183 Ribonucleotide reductase large chain signature 453 476 4.5E-31 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 PRINTS PR01183 Ribonucleotide reductase large chain signature 385 408 4.5E-31 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 PRINTS PR01183 Ribonucleotide reductase large chain signature 238 257 4.5E-31 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 PRINTS PR01183 Ribonucleotide reductase large chain signature 425 447 4.5E-31 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 Gene3D G3DSA:3.20.70.20 66 648 3.9E-145 T 29-03-2018 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 Pfam PF03477 ATP cone domain 3 91 7.4E-19 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWR56_RS05835 25be188163a3fdc14afff618a5c5a103 729 SUPERFAMILY SSF51998 162 645 2.93E-124 T 29-03-2018 CWR56_RS07325 c1e38b39ad9c419bad62c9dae66dde3e 217 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 11 216 3.4E-56 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CWR56_RS07325 c1e38b39ad9c419bad62c9dae66dde3e 217 Pfam PF03006 Haemolysin-III related 10 209 3.2E-41 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CWR56_RS06600 a17d98015372d5e318a6cef39c30d128 259 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 249 8.4E-47 T 29-03-2018 IPR000150 Cof family GO:0016787 CWR56_RS06600 a17d98015372d5e318a6cef39c30d128 259 SUPERFAMILY SSF56784 1 247 7.6E-54 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS06600 a17d98015372d5e318a6cef39c30d128 259 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 248 2.9E-52 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS06600 a17d98015372d5e318a6cef39c30d128 259 Gene3D G3DSA:3.40.50.1000 1 247 1.2E-29 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS06600 a17d98015372d5e318a6cef39c30d128 259 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 229 7.5E-22 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 Gene3D G3DSA:1.10.10.60 42 142 4.3E-9 T 29-03-2018 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 Gene3D G3DSA:1.10.10.60 4 41 2.8E-14 T 29-03-2018 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 3.9E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 SUPERFAMILY SSF46689 3 72 6.62E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS13215 53430b70481e4b07c1d35fdc18815962 190 SUPERFAMILY SSF48498 84 189 3.76E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR56_RS16870 eefaefe82d7a72a3c36796a7a329217c 133 Pfam PF12647 RNHCP domain 18 106 4.6E-38 T 29-03-2018 IPR024439 RNHCP domain CWR56_RS16015 da1e3d9734b720483ba84ac28cf19012 179 SUPERFAMILY SSF52218 1 177 1.93E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS16015 da1e3d9734b720483ba84ac28cf19012 179 Gene3D G3DSA:3.40.50.360 1 178 2.7E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS16015 da1e3d9734b720483ba84ac28cf19012 179 Pfam PF03358 NADPH-dependent FMN reductase 4 124 6.7E-23 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS05240 ce729ae2b54af3ca4891595c99409584 109 SUPERFAMILY SSF46785 5 107 1.09E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05240 ce729ae2b54af3ca4891595c99409584 109 Gene3D G3DSA:1.10.10.10 1 100 5.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05240 ce729ae2b54af3ca4891595c99409584 109 Pfam PF03551 Transcriptional regulator PadR-like family 16 88 1.0E-19 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR56_RS14920 5f967a3839e09296d43392402d9f2429 379 Gene3D G3DSA:3.40.50.1980 80 207 1.7E-10 T 29-03-2018 CWR56_RS14920 5f967a3839e09296d43392402d9f2429 379 Pfam PF01497 Periplasmic binding protein 117 341 3.5E-23 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR56_RS14920 5f967a3839e09296d43392402d9f2429 379 Gene3D G3DSA:3.40.50.1980 208 368 1.8E-26 T 29-03-2018 CWR56_RS14920 5f967a3839e09296d43392402d9f2429 379 SUPERFAMILY SSF53807 93 365 2.79E-36 T 29-03-2018 CWR56_RS15900 2c1929f1d66eba218f95233277557b59 132 Gene3D G3DSA:3.10.180.10 6 130 5.7E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS15900 2c1929f1d66eba218f95233277557b59 132 SUPERFAMILY SSF54593 1 123 1.24E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS07825 4722db640588bcd6415468cceab2266c 263 Pfam PF08282 haloacid dehalogenase-like hydrolase 121 226 2.8E-7 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07825 4722db640588bcd6415468cceab2266c 263 SUPERFAMILY SSF56784 2 223 1.03E-17 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS07825 4722db640588bcd6415468cceab2266c 263 Gene3D G3DSA:3.40.50.1000 1 242 1.1E-9 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 SUPERFAMILY SSF56784 1 205 1.57E-41 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 Gene3D G3DSA:3.40.50.1000 82 220 3.2E-22 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 1 189 9.2E-77 T 29-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 1 188 3.0E-56 T 29-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 66 188 1.3E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 Gene3D G3DSA:1.10.150.240 14 81 1.5E-19 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR56_RS15630 c1e54406897334b9d45f780c7b60ada9 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 188 2.1E-26 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS00635 62235d17f40eae99297ba335ec9e7acf 260 Gene3D G3DSA:3.40.50.2020 72 257 4.9E-22 T 29-03-2018 CWR56_RS00635 62235d17f40eae99297ba335ec9e7acf 260 SUPERFAMILY SSF53271 79 255 5.64E-29 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 556 578 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 SUPERFAMILY SSF48168 1 160 4.05E-47 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 2 698 7.5E-301 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 89 686 2.1E-157 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 SUPERFAMILY SSF51998 162 686 1.25E-166 T 29-03-2018 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 Pfam PF02867 Ribonucleotide reductase, barrel domain 163 682 3.2E-137 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 PRINTS PR01183 Ribonucleotide reductase large chain signature 482 505 1.1E-29 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 PRINTS PR01183 Ribonucleotide reductase large chain signature 454 476 1.1E-29 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 PRINTS PR01183 Ribonucleotide reductase large chain signature 567 594 1.1E-29 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 PRINTS PR01183 Ribonucleotide reductase large chain signature 238 257 1.1E-29 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 PRINTS PR01183 Ribonucleotide reductase large chain signature 371 382 1.1E-29 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 PRINTS PR01183 Ribonucleotide reductase large chain signature 415 438 1.1E-29 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 Pfam PF08343 Ribonucleotide reductase N-terminal 3 84 2.4E-27 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 Gene3D G3DSA:3.20.70.20 65 690 9.2E-149 T 29-03-2018 CWR56_RS14900 a5819481758dca829cd4e0ac1858e435 699 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 87 158 4.9E-14 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR56_RS18130 fc178cfa0497a8dc0134fdd02e9fff3b 95 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 88 6.0E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS18130 fc178cfa0497a8dc0134fdd02e9fff3b 95 SUPERFAMILY SSF52794 1 90 4.45E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS18130 fc178cfa0497a8dc0134fdd02e9fff3b 95 Gene3D G3DSA:3.40.50.2300 1 95 4.1E-16 T 29-03-2018 CWR56_RS02345 4a79884d4a585d889d8cbd5bedece01b 224 SMART SM00382 32 218 4.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02345 4a79884d4a585d889d8cbd5bedece01b 224 Gene3D G3DSA:3.40.50.300 1 223 5.6E-63 T 29-03-2018 CWR56_RS02345 4a79884d4a585d889d8cbd5bedece01b 224 Pfam PF00005 ABC transporter 23 169 2.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS02345 4a79884d4a585d889d8cbd5bedece01b 224 SUPERFAMILY SSF52540 3 222 7.31E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02345 4a79884d4a585d889d8cbd5bedece01b 224 ProSitePatterns PS01095 Chitinases family 18 active site. 23 31 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CWR56_RS02345 4a79884d4a585d889d8cbd5bedece01b 224 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS08840 fdd41daadb7b51b3f03b67e81bdfd8aa 337 SUPERFAMILY SSF51569 1 336 3.76E-115 T 29-03-2018 CWR56_RS08840 fdd41daadb7b51b3f03b67e81bdfd8aa 337 Gene3D G3DSA:3.30.70.1140 1 70 4.9E-20 T 29-03-2018 CWR56_RS08840 fdd41daadb7b51b3f03b67e81bdfd8aa 337 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 71 328 3.7E-122 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWR56_RS08840 fdd41daadb7b51b3f03b67e81bdfd8aa 337 Pfam PF00793 DAHP synthetase I family 91 327 1.1E-73 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CWR56_RS08840 fdd41daadb7b51b3f03b67e81bdfd8aa 337 Gene3D G3DSA:3.20.20.70 71 333 1.2E-77 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS14515 03a490d7e7f69fcaea928871d9256cd1 179 Pfam PF06541 Putative ABC-transporter type IV 13 166 2.2E-33 T 29-03-2018 IPR010540 Putative ABC-transporter type IV CmpB/TMEM229 CWR56_RS03250 7690a7876b332ee45db084a63defdc4f 335 Pfam PF12680 SnoaL-like domain 11 131 6.0E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWR56_RS03250 7690a7876b332ee45db084a63defdc4f 335 Gene3D G3DSA:3.10.450.50 170 324 3.2E-8 T 29-03-2018 CWR56_RS03250 7690a7876b332ee45db084a63defdc4f 335 Gene3D G3DSA:3.10.450.50 5 148 3.6E-13 T 29-03-2018 CWR56_RS03250 7690a7876b332ee45db084a63defdc4f 335 SUPERFAMILY SSF54427 8 152 4.03E-25 T 29-03-2018 IPR032710 NTF2-like domain CWR56_RS03250 7690a7876b332ee45db084a63defdc4f 335 SUPERFAMILY SSF54427 184 327 2.51E-17 T 29-03-2018 IPR032710 NTF2-like domain CWR56_RS07405 29738a09c40cf85a4657b8fa684dfbc2 273 Pfam PF02625 XdhC and CoxI family 11 73 7.7E-17 T 29-03-2018 IPR003777 XdhC- CoxI CWR56_RS07405 29738a09c40cf85a4657b8fa684dfbc2 273 Pfam PF13478 XdhC Rossmann domain 124 264 9.7E-41 T 29-03-2018 IPR027051 XdhC Rossmann domain CWR56_RS07405 29738a09c40cf85a4657b8fa684dfbc2 273 Gene3D G3DSA:3.40.50.20 117 209 4.6E-4 T 29-03-2018 CWR56_RS15985 767d1437deca8908d945207b83d7308b 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 40 383 1.2E-49 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS15985 767d1437deca8908d945207b83d7308b 404 SUPERFAMILY SSF53686 22 397 2.36E-57 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR56_RS15985 767d1437deca8908d945207b83d7308b 404 Gene3D G3DSA:3.40.50.1100 184 396 4.9E-29 T 29-03-2018 CWR56_RS15985 767d1437deca8908d945207b83d7308b 404 Gene3D G3DSA:3.40.50.1100 1 183 1.2E-32 T 29-03-2018 CWR56_RS15985 767d1437deca8908d945207b83d7308b 404 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 24 398 8.3E-180 T 29-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 CWR56_RS15985 767d1437deca8908d945207b83d7308b 404 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 3 399 4.7E-200 T 29-03-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 CWR56_RS13395 49790d21df7b90f95718b4e09511b2bc 117 PIRSF PIRSF018579 1 113 1.1E-33 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 CWR56_RS13395 49790d21df7b90f95718b4e09511b2bc 117 Pfam PF06947 Protein of unknown function (DUF1290) 24 107 1.7E-35 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 CWR56_RS03265 33fe2c3bea5f21c8ca4a82937a1c4822 532 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 433 5.5E-81 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS03265 33fe2c3bea5f21c8ca4a82937a1c4822 532 Pfam PF00474 Sodium:solute symporter family 34 433 7.4E-51 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS03545 a643e0ca035d875b2f1978c9ff225979 312 Gene3D G3DSA:3.20.20.70 14 243 4.1E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS03545 a643e0ca035d875b2f1978c9ff225979 312 Pfam PF04055 Radical SAM superfamily 30 192 2.2E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS03545 a643e0ca035d875b2f1978c9ff225979 312 SMART SM00729 24 233 1.5E-23 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS03545 a643e0ca035d875b2f1978c9ff225979 312 SUPERFAMILY SSF102114 25 284 2.22E-32 T 29-03-2018 CWR56_RS01035 e61e0c7a89ac9d26ea8be736fbeda17d 351 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 7 327 7.3E-88 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS01035 e61e0c7a89ac9d26ea8be736fbeda17d 351 Pfam PF02378 Phosphotransferase system, EIIC 16 274 8.4E-11 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS06850 b65dd6f3eec8823a182237c040794b9f 229 Gene3D G3DSA:3.40.50.150 2 163 2.9E-12 T 29-03-2018 CWR56_RS06850 b65dd6f3eec8823a182237c040794b9f 229 SUPERFAMILY SSF53335 4 141 6.06E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS06850 b65dd6f3eec8823a182237c040794b9f 229 Pfam PF12847 Methyltransferase domain 3 153 2.9E-53 T 29-03-2018 CWR56_RS06850 b65dd6f3eec8823a182237c040794b9f 229 PIRSF PIRSF018637 1 229 1.4E-70 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 Pfam PF00005 ABC transporter 338 466 3.1E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 Pfam PF00005 ABC transporter 20 188 1.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 SUPERFAMILY SSF52540 129 266 1.42E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 SUPERFAMILY SSF52540 3 94 1.42E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 Gene3D G3DSA:3.40.50.300 282 512 5.9E-39 T 29-03-2018 CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 Gene3D G3DSA:3.40.50.300 1 269 5.8E-51 T 29-03-2018 CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 SUPERFAMILY SSF52540 322 509 2.71E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 SMART SM00382 28 238 1.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 SMART SM00382 345 511 1.2E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 Pfam PF12848 ABC transporter 227 311 2.7E-22 T 29-03-2018 IPR032781 ABC-transporter extension domain CWR56_RS16820 5d8d86960d16a294b4391079455f5e30 512 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS05795 dd5f9df83d3a90330151a02e13122bea 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS05795 dd5f9df83d3a90330151a02e13122bea 90 Pfam PF00886 Ribosomal protein S16 9 67 6.9E-26 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05795 dd5f9df83d3a90330151a02e13122bea 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 2.3E-34 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05795 dd5f9df83d3a90330151a02e13122bea 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.371 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05795 dd5f9df83d3a90330151a02e13122bea 90 SUPERFAMILY SSF54565 2 84 3.27E-33 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS05795 dd5f9df83d3a90330151a02e13122bea 90 Gene3D G3DSA:3.30.1320.10 2 85 2.3E-34 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS11795 dba200f1d9dbac1ea9e6d6b14116d0d5 485 Pfam PF02554 Carbon starvation protein CstA 4 177 1.2E-25 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CWR56_RS11795 dba200f1d9dbac1ea9e6d6b14116d0d5 485 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 321 436 1.9E-20 T 29-03-2018 IPR025299 CstA, C-terminal domain CWR56_RS03510 a6b4e496832b3d7091a23641ab63aeb5 314 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 16 247 6.3E-38 T 29-03-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel CWR56_RS03510 a6b4e496832b3d7091a23641ab63aeb5 314 SUPERFAMILY SSF51717 54 231 7.14E-5 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS03510 a6b4e496832b3d7091a23641ab63aeb5 314 Gene3D G3DSA:3.20.20.20 15 314 1.8E-25 T 29-03-2018 CWR56_RS16435 731acbe88160c755b12d41214e9823b1 280 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 4 277 1.6E-75 T 29-03-2018 IPR011862 Phosphate binding protein GO:0006810 CWR56_RS16435 731acbe88160c755b12d41214e9823b1 280 Gene3D G3DSA:3.40.190.10 160 280 6.8E-21 T 29-03-2018 CWR56_RS16435 731acbe88160c755b12d41214e9823b1 280 SUPERFAMILY SSF53850 39 278 7.04E-73 T 29-03-2018 CWR56_RS16435 731acbe88160c755b12d41214e9823b1 280 Pfam PF12849 PBP superfamily domain 31 265 4.7E-41 T 29-03-2018 IPR024370 PBP domain CWR56_RS16435 731acbe88160c755b12d41214e9823b1 280 Gene3D G3DSA:3.40.190.10 37 159 1.1E-35 T 29-03-2018 CWR56_RS16655 aa3904814400ddedba34997d8d1ef4af 427 Gene3D G3DSA:1.20.1250.20 228 422 9.6E-25 T 29-03-2018 CWR56_RS16655 aa3904814400ddedba34997d8d1ef4af 427 SUPERFAMILY SSF103473 14 420 6.67E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS16655 aa3904814400ddedba34997d8d1ef4af 427 Pfam PF07690 Major Facilitator Superfamily 24 266 1.7E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS16655 aa3904814400ddedba34997d8d1ef4af 427 Gene3D G3DSA:1.20.1250.20 10 217 6.3E-27 T 29-03-2018 CWR56_RS08555 71becd85e1e0862cc20f0b73cf0b89e8 120 SUPERFAMILY SSF52833 1 115 2.18E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS08555 71becd85e1e0862cc20f0b73cf0b89e8 120 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 9.9E-34 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CWR56_RS08555 71becd85e1e0862cc20f0b73cf0b89e8 120 Gene3D G3DSA:3.40.30.10 1 116 4.8E-36 T 29-03-2018 CWR56_RS08555 71becd85e1e0862cc20f0b73cf0b89e8 120 Pfam PF03960 ArsC family 35 113 3.8E-14 T 29-03-2018 IPR006660 Arsenate reductase-like CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 SUPERFAMILY SSF50249 129 185 2.91E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 PIRSF PIRSF005901 1 185 3.8E-66 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Pfam PF09285 Elongation factor P, C-terminal 130 184 6.6E-29 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.1E-26 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 SUPERFAMILY SSF50249 65 126 2.06E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Gene3D G3DSA:2.30.30.30 2 60 1.9E-25 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 1.2E-22 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.831 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 5.8E-79 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 SMART SM00841 129 184 7.3E-35 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Gene3D G3DSA:2.40.50.140 64 127 1.5E-25 T 29-03-2018 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 SUPERFAMILY SSF50104 1 62 2.56E-21 T 29-03-2018 IPR008991 Translation protein SH3-like domain CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 SMART SM01185 67 121 8.8E-27 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CWR56_RS05755 cda2b359e941f74eba265a8d48f0eb05 185 Gene3D G3DSA:2.40.50.140 129 184 1.6E-29 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 162 168 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 Gene3D G3DSA:3.40.50.150 30 299 1.1E-45 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 Pfam PF02384 N-6 DNA Methylase 22 284 1.3E-21 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 Pfam PF12950 TaqI-like C-terminal specificity domain 377 528 6.0E-12 T 29-03-2018 IPR025931 TaqI-like C-terminal specificity domain CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 Gene3D G3DSA:3.90.220.10 321 537 5.5E-31 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 28 44 5.9E-18 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 195 219 5.9E-18 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 58 72 5.9E-18 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 159 171 5.9E-18 T 29-03-2018 CWR56_RS13990 af1fe328427afddc40773388cc3d2240 577 SUPERFAMILY SSF53335 5 452 3.41E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS12290 f4f5425d9922b9d707faf89ef486a2c8 200 Pfam PF14242 Domain of unknown function (DUF4342) 60 134 8.3E-22 T 29-03-2018 IPR025642 Domain of unknown function DUF4342 CWR56_RS12290 f4f5425d9922b9d707faf89ef486a2c8 200 SUPERFAMILY SSF46934 5 54 8.25E-8 T 29-03-2018 IPR009060 UBA-like GO:0005515 CWR56_RS12290 f4f5425d9922b9d707faf89ef486a2c8 200 Gene3D G3DSA:1.10.8.10 2 64 2.4E-13 T 29-03-2018 CWR56_RS12545 ac124749c295d4509598ebf1e06bb010 123 Pfam PF07009 NusG domain II 9 111 9.8E-30 T 29-03-2018 IPR024045 NusG, domain 2 CWR56_RS12545 ac124749c295d4509598ebf1e06bb010 123 Gene3D G3DSA:2.60.320.10 18 122 3.3E-29 T 29-03-2018 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 SUPERFAMILY SSF55031 183 290 3.14E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 Gene3D G3DSA:3.40.630.10 1 292 7.5E-44 T 29-03-2018 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 Gene3D G3DSA:3.40.630.10 360 450 3.3E-10 T 29-03-2018 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 PIRSF PIRSF037227 1 455 6.8E-165 T 29-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 SUPERFAMILY SSF53187 294 323 1.73E-56 T 29-03-2018 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 SUPERFAMILY SSF53187 368 432 1.73E-56 T 29-03-2018 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 SUPERFAMILY SSF53187 3 195 1.73E-56 T 29-03-2018 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 390 4.7E-71 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS04175 5085319b49f2ad790b83fc5a82405ff9 455 Pfam PF07687 Peptidase dimerisation domain 182 273 9.0E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 Pfam PF01979 Amidohydrolase family 50 376 2.0E-16 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 SUPERFAMILY SSF51338 350 381 3.09E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 SUPERFAMILY SSF51338 12 53 3.09E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 Gene3D G3DSA:2.30.40.10 7 68 6.1E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 PIRSF PIRSF038994 2 383 2.8E-127 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 SUPERFAMILY SSF51556 54 350 2.87E-97 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 21 376 1.2E-97 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWR56_RS17215 bc2ee0ea8569f2d4adc68b0c0b323a60 384 Gene3D G3DSA:3.20.20.140 69 350 1.0E-96 T 29-03-2018 CWR56_RS10900 29cef5a5ed45888a17d296cfcf721b5d 67 Pfam PF09035 Excisionase from transposon Tn916 3 63 2.9E-18 T 29-03-2018 IPR015122 Excisionase from transposon Tn916 CWR56_RS10900 29cef5a5ed45888a17d296cfcf721b5d 67 ProDom PD054970 EXCISIONASE DNA TRANSPOSON TN916 XIS TRANSPOSABLE XIS-TN FROM INTEGRATION ELEMENT 3 53 2.0E-21 T 29-03-2018 IPR015122 Excisionase from transposon Tn916 CWR56_RS10900 29cef5a5ed45888a17d296cfcf721b5d 67 PIRSF PIRSF004323 1 67 9.2E-45 T 29-03-2018 IPR015122 Excisionase from transposon Tn916 CWR56_RS08915 3838b72e728d96f72c86549dfff39b02 501 SUPERFAMILY SSF53041 1 156 7.85E-23 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS08915 3838b72e728d96f72c86549dfff39b02 501 Pfam PF00239 Resolvase, N terminal domain 3 155 4.4E-19 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS08915 3838b72e728d96f72c86549dfff39b02 501 Pfam PF07508 Recombinase 181 284 5.2E-27 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWR56_RS08915 3838b72e728d96f72c86549dfff39b02 501 SMART SM00857 3 156 2.6E-26 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR56_RS08915 3838b72e728d96f72c86549dfff39b02 501 Pfam PF13408 Recombinase zinc beta ribbon domain 297 346 2.7E-6 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CWR56_RS08915 3838b72e728d96f72c86549dfff39b02 501 Gene3D G3DSA:3.40.50.1390 1 165 2.9E-30 T 29-03-2018 CWR56_RS03900 dfccc18305dc3bb976f31198a05c575e 420 Pfam PF03600 Citrate transporter 23 352 2.1E-18 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CWR56_RS12495 2554f23ec6b2167f54c9068d3e79bdc6 173 SUPERFAMILY SSF46785 2 147 1.81E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12495 2554f23ec6b2167f54c9068d3e79bdc6 173 Gene3D G3DSA:1.10.10.10 1 79 2.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12495 2554f23ec6b2167f54c9068d3e79bdc6 173 SMART SM00418 2 90 0.0023 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR56_RS12495 2554f23ec6b2167f54c9068d3e79bdc6 173 Pfam PF12840 Helix-turn-helix domain 2 61 5.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04880 7a77a5e88b0eac24b8afbde9d44ec48e 337 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 332 9.2E-62 T 29-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 CWR56_RS14945 ddde4959338271d4d9d6b7055204912c 255 Pfam PF00005 ABC transporter 25 172 1.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS14945 ddde4959338271d4d9d6b7055204912c 255 SUPERFAMILY SSF52540 4 224 1.86E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS14945 ddde4959338271d4d9d6b7055204912c 255 SMART SM00382 33 221 4.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS14945 ddde4959338271d4d9d6b7055204912c 255 Gene3D G3DSA:3.40.50.300 1 239 6.1E-63 T 29-03-2018 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 SUPERFAMILY SSF63848 99 136 1.24E-7 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 Gene3D G3DSA:3.30.750.50 12 90 4.8E-12 T 29-03-2018 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 11 222 17.709 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 129 219 2.3E-22 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 100 136 1.7E-7 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 Gene3D G3DSA:2.160.20.70 91 132 2.9E-9 T 29-03-2018 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 Gene3D G3DSA:2.160.20.70 133 225 6.2E-25 T 29-03-2018 CWR56_RS05215 00c34d7589ec94ab9a1228ca41ddb627 227 SUPERFAMILY SSF63848 127 221 3.66E-21 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CWR56_RS16470 f0f77ba1ff8c7db5a0d3352e77345e12 351 Gene3D G3DSA:3.40.50.10490 201 339 5.2E-13 T 29-03-2018 CWR56_RS16470 f0f77ba1ff8c7db5a0d3352e77345e12 351 Gene3D G3DSA:3.40.50.10490 1 200 7.3E-30 T 29-03-2018 CWR56_RS16470 f0f77ba1ff8c7db5a0d3352e77345e12 351 SUPERFAMILY SSF53697 7 337 1.48E-49 T 29-03-2018 CWR56_RS16470 f0f77ba1ff8c7db5a0d3352e77345e12 351 Pfam PF01380 SIS domain 34 156 4.3E-10 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS11110 44f901c05911d266e3404c4ca1dd0885 464 Gene3D G3DSA:3.40.50.300 87 391 6.6E-20 T 29-03-2018 CWR56_RS11110 44f901c05911d266e3404c4ca1dd0885 464 SUPERFAMILY SSF52540 216 389 1.53E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11110 44f901c05911d266e3404c4ca1dd0885 464 Pfam PF01580 FtsK/SpoIIIE family 217 301 1.7E-5 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWR56_RS13905 8ce3dced80b48d25f42a1c0f032eb2e5 204 SUPERFAMILY SSF56281 6 204 1.21E-55 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS13905 8ce3dced80b48d25f42a1c0f032eb2e5 204 Gene3D G3DSA:3.60.15.10 1 202 6.5E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS13905 8ce3dced80b48d25f42a1c0f032eb2e5 204 SMART SM00849 12 188 2.0E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS13905 8ce3dced80b48d25f42a1c0f032eb2e5 204 Pfam PF00753 Metallo-beta-lactamase superfamily 12 188 8.1E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS17250 7553b7abb47256eda4ea4016fe3dd65b 120 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 8 115 1.4E-32 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CWR56_RS17250 7553b7abb47256eda4ea4016fe3dd65b 120 Gene3D G3DSA:2.30.30.110 4 120 4.7E-39 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWR56_RS17250 7553b7abb47256eda4ea4016fe3dd65b 120 PIRSF PIRSF033490 5 117 7.4E-37 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CWR56_RS17250 7553b7abb47256eda4ea4016fe3dd65b 120 SUPERFAMILY SSF50118 7 117 8.99E-42 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWR56_RS02745 3d2c63a0ce40bac2d45bb309f905f41d 1736 Gene3D G3DSA:1.20.58.60 383 1199 0.03 T 29-03-2018 CWR56_RS02745 3d2c63a0ce40bac2d45bb309f905f41d 1736 SUPERFAMILY SSF52540 11 198 4.95E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02745 3d2c63a0ce40bac2d45bb309f905f41d 1736 Pfam PF01926 50S ribosome-binding GTPase 32 177 1.3E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CWR56_RS02745 3d2c63a0ce40bac2d45bb309f905f41d 1736 Gene3D G3DSA:3.40.50.300 1 219 2.1E-10 T 29-03-2018 CWR56_RS05595 a2d6a95a8c5f93623998c931f64b7ec8 270 SUPERFAMILY SSF53167 2 270 1.96E-98 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR56_RS05595 a2d6a95a8c5f93623998c931f64b7ec8 270 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 21 267 1.6E-112 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CWR56_RS05595 a2d6a95a8c5f93623998c931f64b7ec8 270 PIRSF PIRSF000477 1 270 6.0E-117 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CWR56_RS05595 a2d6a95a8c5f93623998c931f64b7ec8 270 Pfam PF01048 Phosphorylase superfamily 21 267 6.7E-53 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR56_RS05595 a2d6a95a8c5f93623998c931f64b7ec8 270 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 21 267 1.5E-113 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CWR56_RS05595 a2d6a95a8c5f93623998c931f64b7ec8 270 Gene3D G3DSA:3.40.50.1580 1 270 8.7E-73 T 29-03-2018 CWR56_RS07355 209ea87a17975c220ac6c55b11bf5f31 201 SUPERFAMILY SSF52317 3 199 5.14E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS07355 209ea87a17975c220ac6c55b11bf5f31 201 Gene3D G3DSA:3.40.50.880 1 201 2.1E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS07355 209ea87a17975c220ac6c55b11bf5f31 201 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 199 34.172 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CWR56_RS07355 209ea87a17975c220ac6c55b11bf5f31 201 PIRSF PIRSF000495 1 201 1.6E-71 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CWR56_RS07355 209ea87a17975c220ac6c55b11bf5f31 201 Pfam PF00117 Glutamine amidotransferase class-I 4 187 7.6E-20 T 29-03-2018 IPR017926 Glutamine amidotransferase CWR56_RS07355 209ea87a17975c220ac6c55b11bf5f31 201 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 197 1.1E-69 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CWR56_RS06395 b4c1e557494b0dcf3f9ffdac0321582d 232 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 12 140 1.9E-22 T 29-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 CWR56_RS02445 5a7c9b71d8379440b48573d30adb4b06 120 Gene3D G3DSA:3.40.50.2300 2 120 1.6E-36 T 29-03-2018 CWR56_RS02445 5a7c9b71d8379440b48573d30adb4b06 120 SMART SM00448 3 115 3.6E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS02445 5a7c9b71d8379440b48573d30adb4b06 120 SUPERFAMILY SSF52172 4 120 1.1E-37 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS02445 5a7c9b71d8379440b48573d30adb4b06 120 Pfam PF00072 Response regulator receiver domain 5 115 5.0E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS13525 89ba3aa8212f21ce3d245d8b657c0dbc 270 SUPERFAMILY SSF161098 70 256 2.62E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS13525 89ba3aa8212f21ce3d245d8b657c0dbc 270 Gene3D G3DSA:1.10.3720.10 6 265 1.2E-39 T 29-03-2018 CWR56_RS13525 89ba3aa8212f21ce3d245d8b657c0dbc 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 262 1.9E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS07210 7113a48eb3fbf4e36f4b345e95481978 304 Pfam PF00892 EamA-like transporter family 146 277 4.0E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS07210 7113a48eb3fbf4e36f4b345e95481978 304 Pfam PF00892 EamA-like transporter family 5 137 1.3E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS07210 7113a48eb3fbf4e36f4b345e95481978 304 SUPERFAMILY SSF103481 41 138 1.7E-9 T 29-03-2018 CWR56_RS07210 7113a48eb3fbf4e36f4b345e95481978 304 SUPERFAMILY SSF103481 181 278 3.27E-12 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 42 61 2.9E-13 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 609 628 2.9E-13 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 528 544 2.9E-13 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 639 658 2.9E-13 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 669 687 2.9E-13 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 Pfam PF13654 AAA domain 6 502 4.0E-163 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 SUPERFAMILY SSF52540 11 85 2.4E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 SUPERFAMILY SSF52540 323 501 2.4E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 SUPERFAMILY SSF54211 526 720 6.83E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 Gene3D G3DSA:3.30.230.10 505 742 2.5E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 SUPERFAMILY SSF52540 12 248 2.2E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 Gene3D G3DSA:3.40.50.300 2 363 1.6E-8 T 29-03-2018 CWR56_RS02605 6a84f599a7ffd682aec20e655e8397b4 745 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 612 716 3.3E-9 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CWR56_RS06565 3a9afb3bce9b446a36b49038e3ec471e 642 Pfam PF03169 OPT oligopeptide transporter protein 34 595 1.8E-81 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CWR56_RS06565 3a9afb3bce9b446a36b49038e3ec471e 642 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 32 591 1.5E-58 T 29-03-2018 IPR004814 Oligopeptide transporter OPT CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 SUPERFAMILY SSF64518 1 289 1.2E-86 T 29-03-2018 CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 Gene3D G3DSA:1.20.1330.10 38 262 7.7E-69 T 29-03-2018 CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 Pfam PF00700 Bacterial flagellin C-terminal helical region 206 289 1.5E-26 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 141 4.8E-41 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 PRINTS PR00207 Flagellin signature 35 52 8.6E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 PRINTS PR00207 Flagellin signature 74 93 8.6E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CWR56_RS01205 673f0af6d3756767dc40c2c4c09fd8fc 290 PRINTS PR00207 Flagellin signature 109 132 8.6E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 Gene3D G3DSA:3.40.30.10 1 105 3.8E-33 T 29-03-2018 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 PRINTS PR00421 Thioredoxin family signature 21 29 2.8E-8 T 29-03-2018 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 PRINTS PR00421 Thioredoxin family signature 29 38 2.8E-8 T 29-03-2018 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 PRINTS PR00421 Thioredoxin family signature 69 80 2.8E-8 T 29-03-2018 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 PIRSF PIRSF000077 1 105 7.4E-36 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 SUPERFAMILY SSF52833 2 104 3.72E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 103 9.9E-36 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR56_RS15120 9a762d38096002f97d378e91ca7e64b5 105 Pfam PF00085 Thioredoxin 2 102 8.0E-31 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 SMART SM00645 90 325 1.7E-6 T 29-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 Gene3D G3DSA:3.90.70.10 94 262 5.0E-25 T 29-03-2018 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 Gene3D G3DSA:2.40.50.170 263 330 3.1E-15 T 29-03-2018 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 Pfam PF00112 Papain family cysteine protease 104 313 1.0E-18 T 29-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 260 270 - T 29-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 Pfam PF04122 Putative cell wall binding repeat 2 507 593 3.5E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 Pfam PF04122 Putative cell wall binding repeat 2 605 694 6.0E-17 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 Pfam PF04122 Putative cell wall binding repeat 2 703 789 5.7E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14140 078e3f7cd030c57eb1cf1bdddb7c2071 803 SUPERFAMILY SSF54001 96 312 2.14E-40 T 29-03-2018 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 341 529 3.1E-50 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Gene3D G3DSA:2.40.240.10 461 548 9.8E-28 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 SUPERFAMILY SSF52374 10 333 3.22E-97 T 29-03-2018 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Gene3D G3DSA:3.40.50.620 42 152 1.5E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Gene3D G3DSA:3.40.50.620 154 258 1.0E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 550 49.818 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 SUPERFAMILY SSF50715 341 548 9.94E-66 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 27 335 3.8E-112 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 33 44 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 550 4.9E-217 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Gene3D G3DSA:1.10.1160.10 259 336 3.0E-33 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 44 55 1.8E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 59 72 1.8E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 30 42 1.8E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 218 1.8E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Gene3D G3DSA:3.40.50.620 19 41 0.056 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS09870 4603bb5e0d241193ec6218781850ee86 554 Gene3D G3DSA:2.40.240.10 346 460 1.1E-46 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR56_RS01500 632cae410dfc0e48d67c109286ff0730 364 Gene3D G3DSA:1.10.260.40 1 109 2.3E-21 T 29-03-2018 CWR56_RS01500 632cae410dfc0e48d67c109286ff0730 364 SUPERFAMILY SSF47413 4 69 1.46E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS01500 632cae410dfc0e48d67c109286ff0730 364 SMART SM00530 9 64 3.4E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS01500 632cae410dfc0e48d67c109286ff0730 364 Gene3D G3DSA:1.25.40.10 132 301 0.0016 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS01500 632cae410dfc0e48d67c109286ff0730 364 Pfam PF01381 Helix-turn-helix 13 64 1.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS12255 977dd5f11190bfc02af52f4d4c072dab 239 Gene3D G3DSA:3.40.50.970 2 70 2.3E-5 T 29-03-2018 CWR56_RS12255 977dd5f11190bfc02af52f4d4c072dab 239 Gene3D G3DSA:3.40.50.970 71 239 1.9E-33 T 29-03-2018 CWR56_RS12255 977dd5f11190bfc02af52f4d4c072dab 239 SUPERFAMILY SSF52518 12 227 8.66E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS12255 977dd5f11190bfc02af52f4d4c072dab 239 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 46 205 2.0E-20 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 Pfam PF00117 Glutamine amidotransferase class-I 4 187 2.9E-53 T 29-03-2018 IPR017926 Glutamine amidotransferase CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.5E-5 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.5E-5 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 SUPERFAMILY SSF52317 1 190 1.39E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 Gene3D G3DSA:3.40.50.880 1 191 4.8E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.4E-33 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.4E-33 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.4E-33 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.4E-33 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.4E-33 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.4E-33 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.5E-13 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.5E-13 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.5E-13 T 29-03-2018 CWR56_RS06795 b85573e2913bf3d857f294feaab4b7ef 194 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 1.1E-80 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR56_RS08955 c99e3bce869f88b5a3af9d0b75d18bee 413 Pfam PF12679 ABC-2 family transporter protein 3 348 9.6E-11 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS00675 361c14215aa1cfd2a429055ea6030c2b 224 SUPERFAMILY SSF110395 1 212 1.24E-55 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CWR56_RS00675 361c14215aa1cfd2a429055ea6030c2b 224 Pfam PF03932 CutC family 2 197 3.9E-51 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CWR56_RS00675 361c14215aa1cfd2a429055ea6030c2b 224 Gene3D G3DSA:3.20.20.380 1 221 3.3E-65 T 29-03-2018 CWR56_RS00010 32de437885c48f5e6d98f2220473dfb5 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS00010 32de437885c48f5e6d98f2220473dfb5 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.785 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00010 32de437885c48f5e6d98f2220473dfb5 49 Pfam PF00471 Ribosomal protein L33 3 49 2.6E-23 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00010 32de437885c48f5e6d98f2220473dfb5 49 SUPERFAMILY SSF57829 1 49 7.94E-20 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWR56_RS00010 32de437885c48f5e6d98f2220473dfb5 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 3.6E-20 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS11835 3c43ea80184a7cce4ddce98cf7715bba 67 ProDom PD054970 EXCISIONASE DNA TRANSPOSON TN916 XIS TRANSPOSABLE XIS-TN FROM INTEGRATION ELEMENT 3 53 1.0E-21 T 29-03-2018 IPR015122 Excisionase from transposon Tn916 CWR56_RS11835 3c43ea80184a7cce4ddce98cf7715bba 67 Pfam PF09035 Excisionase from transposon Tn916 3 63 1.5E-19 T 29-03-2018 IPR015122 Excisionase from transposon Tn916 CWR56_RS11835 3c43ea80184a7cce4ddce98cf7715bba 67 PIRSF PIRSF004323 1 67 4.8E-46 T 29-03-2018 IPR015122 Excisionase from transposon Tn916 CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.2E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 Gene3D G3DSA:1.10.10.60 48 156 2.1E-8 T 29-03-2018 CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 Gene3D G3DSA:1.10.10.60 2 47 3.2E-16 T 29-03-2018 CWR56_RS09600 41ba2862951fbb9e4bf51ecb3e9c7949 210 SUPERFAMILY SSF46689 3 76 1.49E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS14505 3de33629722b20ed3a67e3328685be21 396 Gene3D G3DSA:3.40.50.1110 271 396 5.4E-6 T 29-03-2018 CWR56_RS14505 3de33629722b20ed3a67e3328685be21 396 SUPERFAMILY SSF52266 300 395 1.97E-6 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR56_RS14505 3de33629722b20ed3a67e3328685be21 396 PIRSF PIRSF021438 1 396 2.6E-146 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CWR56_RS14505 3de33629722b20ed3a67e3328685be21 396 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 8 391 2.6E-112 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CWR56_RS14505 3de33629722b20ed3a67e3328685be21 396 Pfam PF04914 DltD protein 48 394 2.2E-100 T 29-03-2018 IPR006998 DltD CWR56_RS09670 1d5e2d0e6c1ce7dd96afb298e24ef2bf 287 SUPERFAMILY SSF52540 6 225 2.37E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09670 1d5e2d0e6c1ce7dd96afb298e24ef2bf 287 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS09670 1d5e2d0e6c1ce7dd96afb298e24ef2bf 287 SMART SM00382 30 209 2.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09670 1d5e2d0e6c1ce7dd96afb298e24ef2bf 287 Pfam PF00005 ABC transporter 21 160 1.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09670 1d5e2d0e6c1ce7dd96afb298e24ef2bf 287 Gene3D G3DSA:3.40.50.300 3 260 2.5E-49 T 29-03-2018 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 SUPERFAMILY SSF53623 1 297 2.4E-92 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 297 374 5.1E-8 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 42 65 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 PIRSF PIRSF001563 1 432 4.3E-147 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 Gene3D G3DSA:3.90.190.20 299 432 9.2E-29 T 29-03-2018 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 SUPERFAMILY SSF53244 299 430 5.68E-30 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 Pfam PF08245 Mur ligase middle domain 44 270 3.5E-17 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 428 5.3E-120 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWR56_RS16355 9baa53c49a2b4a840271f1d2842f7c9b 432 Gene3D G3DSA:3.40.1190.10 1 298 9.3E-86 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR56_RS14065 ccd9c2230989a9cc89386f7f42a88f05 302 Gene3D G3DSA:3.90.550.10 1 291 2.6E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS14065 ccd9c2230989a9cc89386f7f42a88f05 302 Pfam PF00535 Glycosyl transferase family 2 7 106 3.3E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS14065 ccd9c2230989a9cc89386f7f42a88f05 302 SUPERFAMILY SSF53448 5 227 9.64E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS17640 d0171efdea7d7f5395b9e3de6ed0a8c1 143 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 4 142 3.1E-38 T 29-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS17640 d0171efdea7d7f5395b9e3de6ed0a8c1 143 Pfam PF06754 Phosphonate metabolism protein PhnG 7 142 1.8E-24 T 29-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS18195 d1b15becdcaca96f7a8778cf374573ed 369 SUPERFAMILY SSF53383 6 368 6.64E-38 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS18195 d1b15becdcaca96f7a8778cf374573ed 369 Pfam PF03841 L-seryl-tRNA selenium transferase 14 268 1.1E-12 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CWR56_RS18195 d1b15becdcaca96f7a8778cf374573ed 369 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 4 367 1.6E-180 T 29-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 CWR56_RS18195 d1b15becdcaca96f7a8778cf374573ed 369 Gene3D G3DSA:3.40.640.10 1 251 2.8E-19 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS07995 2c3afdcfbb832be6e58420085c941abd 206 SUPERFAMILY SSF52218 1 192 1.55E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS07995 2c3afdcfbb832be6e58420085c941abd 206 Pfam PF03358 NADPH-dependent FMN reductase 1 148 2.5E-26 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS07995 2c3afdcfbb832be6e58420085c941abd 206 Gene3D G3DSA:3.40.50.360 1 194 2.6E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS13880 37abc226f8b817c445a3d16b934bd12c 268 Pfam PF00795 Carbon-nitrogen hydrolase 6 253 7.7E-47 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS13880 37abc226f8b817c445a3d16b934bd12c 268 Gene3D G3DSA:3.60.110.10 1 266 1.6E-67 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS13880 37abc226f8b817c445a3d16b934bd12c 268 SUPERFAMILY SSF56317 3 261 7.59E-68 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS10825 fa1eb0670bbbb5aa1a45c99e5f0b89be 267 Gene3D G3DSA:3.40.50.1110 3 254 1.2E-23 T 29-03-2018 CWR56_RS10825 fa1eb0670bbbb5aa1a45c99e5f0b89be 267 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 4 231 7.3E-20 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain CWR56_RS10825 fa1eb0670bbbb5aa1a45c99e5f0b89be 267 SUPERFAMILY SSF52266 4 262 3.1E-39 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR56_RS13825 fc61c0f4742ac72400f6ebd8525ec2f1 262 Pfam PF06738 Putative threonine/serine exporter 16 254 3.2E-69 T 29-03-2018 IPR010619 Putative threonine/serine exporter CWR56_RS02495 dea504bbd11629cf27f07e25c19a43b2 287 Gene3D G3DSA:3.90.640.20 191 283 3.3E-24 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS02495 dea504bbd11629cf27f07e25c19a43b2 287 Pfam PF11738 Protein of unknown function (DUF3298) 194 269 2.5E-20 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CWR56_RS02495 dea504bbd11629cf27f07e25c19a43b2 287 Pfam PF13739 Domain of unknown function (DUF4163) 83 174 1.9E-20 T 29-03-2018 IPR025303 Deacetylase PdaC CWR56_RS02495 dea504bbd11629cf27f07e25c19a43b2 287 Gene3D G3DSA:3.30.565.40 70 190 7.7E-21 T 29-03-2018 CWR56_RS01255 c4f6f3852f6dcec244c7764a87e968fa 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 88 131 5.2E-11 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CWR56_RS01255 c4f6f3852f6dcec244c7764a87e968fa 134 Pfam PF00460 Flagella basal body rod protein 7 36 2.8E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CWR56_RS01255 c4f6f3852f6dcec244c7764a87e968fa 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 134 3.2E-46 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 Gene3D G3DSA:3.20.70.20 1 742 1.0E-299 T 29-03-2018 CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 3 742 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 ProSitePatterns PS00850 Glycine radical domain signature. 712 720 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 Pfam PF02901 Pyruvate formate lyase-like 14 601 8.7E-215 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 Pfam PF01228 Glycine radical 617 723 3.4E-45 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 SUPERFAMILY SSF51998 2 741 1.65E-290 T 29-03-2018 CWR56_RS03685 fe22591d46aeab62c86269907b421200 743 PIRSF PIRSF000379 1 742 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWR56_RS09105 4689caa9e0ca62ba8983f60d1300069a 95 SUPERFAMILY SSF143414 5 91 1.57E-31 T 29-03-2018 CWR56_RS09105 4689caa9e0ca62ba8983f60d1300069a 95 SMART SM00877 5 81 6.3E-38 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09105 4689caa9e0ca62ba8983f60d1300069a 95 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 23 42 - T 29-03-2018 IPR020808 Bacterial microcompartments protein, conserved site CWR56_RS09105 4689caa9e0ca62ba8983f60d1300069a 95 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 6 49 3.0E-16 T 29-03-2018 CWR56_RS09105 4689caa9e0ca62ba8983f60d1300069a 95 Pfam PF00936 BMC domain 6 81 3.3E-29 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 Pfam PF13580 SIS domain 40 168 9.3E-13 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 5 298 41.328 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 Gene3D G3DSA:1.10.8.10 247 273 1.4E-8 T 29-03-2018 CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 SUPERFAMILY SSF53697 8 251 1.09E-71 T 29-03-2018 CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 Gene3D G3DSA:3.40.50.10490 2 246 7.6E-53 T 29-03-2018 CWR56_RS15185 df7761e61f6ce2f198eed6000cecec71 304 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 9 298 3.0E-124 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CWR56_RS16035 dd94ee67380262bda69ba20697edd7cb 308 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 218 290 2.2E-20 T 29-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CWR56_RS16035 dd94ee67380262bda69ba20697edd7cb 308 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 218 289 8.1E-25 T 29-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CWR56_RS16035 dd94ee67380262bda69ba20697edd7cb 308 Gene3D G3DSA:1.10.10.10 20 108 0.0011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS14975 6dd95a1120ca7e328ce38d36e843ba5a 101 SMART SM00858 11 87 3.4E-13 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CWR56_RS14975 6dd95a1120ca7e328ce38d36e843ba5a 101 Pfam PF08666 SAF domain 11 87 3.5E-13 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CWR56_RS12190 5fb386baae71e8879fa62eb4aea7f97a 119 Pfam PF06923 Glucitol operon activator protein (GutM) 3 105 9.6E-25 T 29-03-2018 IPR009693 Glucitol operon activator CWR56_RS15760 1edd54610d77dc92d49909b9ec379ee0 1326 TIGRFAM TIGR03237 dnd_assoc_2: DNA phosphorothioation-dependent restriction protein DptH 6 1293 1.8E-227 T 29-03-2018 IPR017646 DNA phosphorothioation-dependent restriction protein DptH CWR56_RS02080 306ed2403ab5a9226fa1a340e3cbf1fb 120 Gene3D G3DSA:3.10.180.10 4 120 3.2E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS02080 306ed2403ab5a9226fa1a340e3cbf1fb 120 SUPERFAMILY SSF54593 1 116 4.54E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS14625 941d0279ce19096bdc2459ad7b81aa0c 312 Gene3D G3DSA:3.40.50.1980 34 152 4.6E-23 T 29-03-2018 CWR56_RS14625 941d0279ce19096bdc2459ad7b81aa0c 312 SUPERFAMILY SSF53807 37 306 1.73E-51 T 29-03-2018 CWR56_RS14625 941d0279ce19096bdc2459ad7b81aa0c 312 Gene3D G3DSA:3.40.50.1980 153 312 4.7E-27 T 29-03-2018 CWR56_RS14625 941d0279ce19096bdc2459ad7b81aa0c 312 Pfam PF01497 Periplasmic binding protein 59 286 1.5E-23 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR56_RS05800 bcaaf8357c817876f4ef4cdd222370ed 75 Hamap MF_00088 UPF0109 protein . 1 75 21.938 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 CWR56_RS05800 bcaaf8357c817876f4ef4cdd222370ed 75 Gene3D G3DSA:3.30.300.20 1 74 8.1E-16 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CWR56_RS05800 bcaaf8357c817876f4ef4cdd222370ed 75 Pfam PF13083 KH domain 2 74 3.8E-24 T 29-03-2018 CWR56_RS05800 bcaaf8357c817876f4ef4cdd222370ed 75 SUPERFAMILY SSF54814 15 59 1.37E-7 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 107 6.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 8.7E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 PIRSF PIRSF000441 1 193 2.9E-80 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 SUPERFAMILY SSF51161 7 175 3.6E-56 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 Gene3D G3DSA:1.10.3130.10 1 60 3.0E-23 T 29-03-2018 CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 Gene3D G3DSA:2.160.10.10 61 195 1.9E-36 T 29-03-2018 CWR56_RS07570 416f93da3cad36fe57afc73de1c4f627 196 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 2.1E-73 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CWR56_RS06330 7ea6a0fd1f9092e8b5b3956e526c130b 65 SMART SM00530 5 60 3.6E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06330 7ea6a0fd1f9092e8b5b3956e526c130b 65 Pfam PF01381 Helix-turn-helix 6 59 2.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06330 7ea6a0fd1f9092e8b5b3956e526c130b 65 Gene3D G3DSA:1.10.3100.10 1 64 4.9E-17 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS06330 7ea6a0fd1f9092e8b5b3956e526c130b 65 SUPERFAMILY SSF47413 2 62 7.51E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS12045 83b3fdb44c2850da602a5e5d0ffd4f35 340 Pfam PF01070 FMN-dependent dehydrogenase 37 182 2.8E-14 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CWR56_RS12045 83b3fdb44c2850da602a5e5d0ffd4f35 340 Pfam PF01070 FMN-dependent dehydrogenase 193 337 1.6E-55 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CWR56_RS12045 83b3fdb44c2850da602a5e5d0ffd4f35 340 PIRSF PIRSF000138 183 339 2.5E-58 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CWR56_RS12045 83b3fdb44c2850da602a5e5d0ffd4f35 340 PIRSF PIRSF000138 3 195 5.6E-21 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CWR56_RS12045 83b3fdb44c2850da602a5e5d0ffd4f35 340 Gene3D G3DSA:3.20.20.70 35 338 1.1E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS12045 83b3fdb44c2850da602a5e5d0ffd4f35 340 SUPERFAMILY SSF51395 38 336 2.56E-59 T 29-03-2018 CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 153 23.9 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 SUPERFAMILY SSF74942 85 153 4.71E-14 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 Gene3D G3DSA:3.30.300.70 1 81 6.4E-27 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 SUPERFAMILY SSF75420 3 84 6.8E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 Pfam PF02576 RimP N-terminal domain 12 84 2.9E-29 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 Gene3D G3DSA:2.30.30.180 88 151 6.3E-17 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWR56_RS06065 faa4feac62467e70b3021481d4ac17f6 153 Pfam PF17384 RimP C-terminal SH3 domain 87 153 4.5E-14 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWR56_RS18840 76ac535da888aa7681575f018220be6b 154 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 147 1.5E-50 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CWR56_RS18840 76ac535da888aa7681575f018220be6b 154 PIRSF PIRSF010607 1 152 6.1E-52 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CWR56_RS12910 8891d7e16ad3857c319487b81a01fc33 95 Gene3D G3DSA:3.40.50.2300 1 91 3.4E-17 T 29-03-2018 CWR56_RS12910 8891d7e16ad3857c319487b81a01fc33 95 SUPERFAMILY SSF52794 1 88 9.94E-21 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12910 8891d7e16ad3857c319487b81a01fc33 95 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 85 9.7E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS05320 88f4bb7771ae1fac68c26fc776d0264c 424 Pfam PF09861 Domain of unknown function (DUF2088) 8 213 2.3E-77 T 29-03-2018 IPR018657 LarA-like, N-terminal CWR56_RS03985 bad5bc5a077d05415b7e965228737e24 395 Pfam PF07690 Major Facilitator Superfamily 14 206 1.3E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS03985 bad5bc5a077d05415b7e965228737e24 395 Pfam PF07690 Major Facilitator Superfamily 211 382 2.5E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS03985 bad5bc5a077d05415b7e965228737e24 395 SUPERFAMILY SSF103473 9 383 1.31E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS03985 bad5bc5a077d05415b7e965228737e24 395 Gene3D G3DSA:1.20.1250.20 190 386 4.9E-26 T 29-03-2018 CWR56_RS03985 bad5bc5a077d05415b7e965228737e24 395 Gene3D G3DSA:1.20.1250.20 2 186 5.2E-22 T 29-03-2018 CWR56_RS00595 62bf2ff46fed673c15fda7d74a5f0cb6 222 Pfam PF01551 Peptidase family M23 119 217 9.7E-22 T 29-03-2018 IPR016047 Peptidase M23 CWR56_RS00595 62bf2ff46fed673c15fda7d74a5f0cb6 222 SUPERFAMILY SSF51261 109 221 3.56E-23 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS00595 62bf2ff46fed673c15fda7d74a5f0cb6 222 Gene3D G3DSA:2.70.70.10 58 222 1.0E-28 T 29-03-2018 CWR56_RS13945 e8c127aaca4735209cf17b5772ea0a09 48 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 7 41 7.1E-14 T 29-03-2018 IPR009229 Staphylococcal AgrD CWR56_RS04650 f83739dfa1a4836bf1aa2a126b788f36 228 Pfam PF16316 Domain of unknown function (DUF4956) 40 140 4.1E-8 T 29-03-2018 IPR032531 Protein of unknown function DUF4956 CWR56_RS14980 49a41390fe0649a6c12d1d7309b18da2 324 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 13 306 1.0E-41 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 CWR56_RS14980 49a41390fe0649a6c12d1d7309b18da2 324 Pfam PF03812 2-keto-3-deoxygluconate permease 2 307 1.6E-121 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 CWR56_RS06985 954fbfef8df4f2c061fbfec741bb7408 243 SUPERFAMILY SSF52540 10 224 6.41E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS06985 954fbfef8df4f2c061fbfec741bb7408 243 Gene3D G3DSA:3.40.50.300 5 239 5.6E-55 T 29-03-2018 CWR56_RS06985 954fbfef8df4f2c061fbfec741bb7408 243 Pfam PF00005 ABC transporter 25 160 8.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS06985 954fbfef8df4f2c061fbfec741bb7408 243 SMART SM00382 34 209 2.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01805 cafce12455a7da113b543d1297454bec 230 SUPERFAMILY SSF56300 1 202 1.22E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS01805 cafce12455a7da113b543d1297454bec 230 PIRSF PIRSF033094 1 230 4.5E-93 T 29-03-2018 IPR014578 Predicted phosphoesterase, CT488 type CWR56_RS01805 cafce12455a7da113b543d1297454bec 230 Gene3D G3DSA:3.60.21.10 2 230 7.7E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS01805 cafce12455a7da113b543d1297454bec 230 Pfam PF00149 Calcineurin-like phosphoesterase 2 195 6.4E-17 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS17120 70445c97590343ab0ad07bf41b60088e 204 SUPERFAMILY SSF53254 1 203 3.85E-50 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CWR56_RS17120 70445c97590343ab0ad07bf41b60088e 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 199 8.2E-48 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR56_RS17120 70445c97590343ab0ad07bf41b60088e 204 SMART SM00855 3 161 1.4E-11 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR56_RS17120 70445c97590343ab0ad07bf41b60088e 204 PIRSF PIRSF000709 3 189 4.1E-22 T 29-03-2018 CWR56_RS17120 70445c97590343ab0ad07bf41b60088e 204 Gene3D G3DSA:3.40.50.1240 1 204 2.2E-45 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CWR56_RS05920 03c5d4f87e44d4231d6c6e56c663c034 148 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CWR56_RS05920 03c5d4f87e44d4231d6c6e56c663c034 148 Pfam PF02082 Transcriptional regulator 1 81 1.6E-29 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CWR56_RS05920 03c5d4f87e44d4231d6c6e56c663c034 148 SUPERFAMILY SSF46785 2 135 2.42E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05920 03c5d4f87e44d4231d6c6e56c663c034 148 Gene3D G3DSA:1.10.10.10 1 146 9.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS05920 03c5d4f87e44d4231d6c6e56c663c034 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 2.2E-43 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CWR56_RS16570 a150885bfe3d9e297417bf3ab7ff3d8a 361 Pfam PF00482 Type II secretion system (T2SS), protein F 30 150 2.8E-23 T 29-03-2018 IPR018076 Type II secretion system F domain CWR56_RS16570 a150885bfe3d9e297417bf3ab7ff3d8a 361 Pfam PF00482 Type II secretion system (T2SS), protein F 231 353 5.1E-24 T 29-03-2018 IPR018076 Type II secretion system F domain CWR56_RS16570 a150885bfe3d9e297417bf3ab7ff3d8a 361 PRINTS PR00812 Bacterial general secretion pathway protein F signature 326 340 5.4E-10 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS16570 a150885bfe3d9e297417bf3ab7ff3d8a 361 PRINTS PR00812 Bacterial general secretion pathway protein F signature 25 37 5.4E-10 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS16570 a150885bfe3d9e297417bf3ab7ff3d8a 361 PRINTS PR00812 Bacterial general secretion pathway protein F signature 122 150 5.4E-10 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS16570 a150885bfe3d9e297417bf3ab7ff3d8a 361 PRINTS PR00812 Bacterial general secretion pathway protein F signature 342 361 5.4E-10 T 29-03-2018 IPR003004 GspF/PilC family CWR56_RS07220 4ddecb71dd19cd5502bdfe845cca4f64 382 Gene3D G3DSA:3.30.70.20 356 382 0.0011 T 29-03-2018 CWR56_RS07220 4ddecb71dd19cd5502bdfe845cca4f64 382 Gene3D G3DSA:3.30.70.20 335 355 3.5E-7 T 29-03-2018 CWR56_RS07220 4ddecb71dd19cd5502bdfe845cca4f64 382 Pfam PF04015 Domain of unknown function (DUF362) 41 244 2.7E-52 T 29-03-2018 IPR007160 Domain of unknown function DUF362 CWR56_RS07220 4ddecb71dd19cd5502bdfe845cca4f64 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 355 366 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS07220 4ddecb71dd19cd5502bdfe845cca4f64 382 Gene3D G3DSA:3.30.70.20 306 334 4.6E-5 T 29-03-2018 CWR56_RS07220 4ddecb71dd19cd5502bdfe845cca4f64 382 SUPERFAMILY SSF54862 306 376 6.91E-15 T 29-03-2018 CWR56_RS07235 4a49bfbe191cac54385e75f374261db4 224 SMART SM00382 31 219 3.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07235 4a49bfbe191cac54385e75f374261db4 224 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS07235 4a49bfbe191cac54385e75f374261db4 224 SUPERFAMILY SSF52540 2 221 2.03E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07235 4a49bfbe191cac54385e75f374261db4 224 Pfam PF00005 ABC transporter 22 171 5.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07235 4a49bfbe191cac54385e75f374261db4 224 Gene3D G3DSA:3.40.50.300 1 223 7.3E-63 T 29-03-2018 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 23 220 4.8E-79 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 197 209 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 Pfam PF00813 FliP family 24 216 9.8E-77 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 149 169 1.0E-58 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 170 191 1.0E-58 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 21 40 1.0E-58 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 40 60 1.0E-58 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 60 79 1.0E-58 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 194 219 1.0E-58 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 149 164 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 79 91 4.9E-19 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 19 28 4.9E-19 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 91 105 4.9E-19 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 119 131 4.9E-19 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 142 154 4.9E-19 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS01330 e3263331a02fa345ed98fed0b1b9172f 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 210 220 4.9E-19 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CWR56_RS10460 62b00857257900ab024e94007bb2cd95 241 Gene3D G3DSA:3.30.70.20 21 48 5.4E-14 T 29-03-2018 CWR56_RS10460 62b00857257900ab024e94007bb2cd95 241 Gene3D G3DSA:3.30.70.20 49 103 5.4E-4 T 29-03-2018 CWR56_RS10460 62b00857257900ab024e94007bb2cd95 241 Gene3D G3DSA:3.30.70.20 2 20 2.0E-6 T 29-03-2018 CWR56_RS10460 62b00857257900ab024e94007bb2cd95 241 SUPERFAMILY SSF54862 3 63 1.04E-16 T 29-03-2018 CWR56_RS10460 62b00857257900ab024e94007bb2cd95 241 Pfam PF12837 4Fe-4S binding domain 5 28 7.6E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 116 170 9.0E-17 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 171 224 2.0E-13 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 308 376 6.9E-13 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 225 287 5.0E-11 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 64 115 3.9E-13 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 5 63 1.1E-13 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Gene3D G3DSA:2.160.20.50 377 441 3.5E-15 T 29-03-2018 CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Pfam PF01391 Collagen triple helix repeat (20 copies) 14 71 6.3E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CWR56_RS16230 ccc77df7ec2fe3fbed2401b848db7209 558 Pfam PF01391 Collagen triple helix repeat (20 copies) 368 425 1.9E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CWR56_RS14320 4a82d3d550520d8218d1627712d2ba50 215 Pfam PF07670 Nucleoside recognition 73 148 7.2E-7 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS09465 7bea2eed2063d5d2c0e06ba8984ac83c 112 Pfam PF12650 Domain of unknown function (DUF3784) 9 110 2.6E-27 T 29-03-2018 IPR017259 Uncharacterised conserved protein UCP037672 CWR56_RS02230 4ef5e6dd5b1af97ea057fa9824f994b6 222 Pfam PF00005 ABC transporter 22 168 3.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS02230 4ef5e6dd5b1af97ea057fa9824f994b6 222 Gene3D G3DSA:3.40.50.300 1 222 6.5E-61 T 29-03-2018 CWR56_RS02230 4ef5e6dd5b1af97ea057fa9824f994b6 222 SMART SM00382 31 218 2.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02230 4ef5e6dd5b1af97ea057fa9824f994b6 222 SUPERFAMILY SSF52540 2 221 9.47E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02230 4ef5e6dd5b1af97ea057fa9824f994b6 222 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04950 ddd04d9b9c29b02952ed225bf579f208 69 SUPERFAMILY SSF158221 1 42 1.12E-12 T 29-03-2018 CWR56_RS04950 ddd04d9b9c29b02952ed225bf579f208 69 Hamap MF_01103 UPF0291 protein . 1 60 13.942 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CWR56_RS04950 ddd04d9b9c29b02952ed225bf579f208 69 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 60 1.6E-19 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CWR56_RS04950 ddd04d9b9c29b02952ed225bf579f208 69 Gene3D G3DSA:1.10.287.540 4 56 1.8E-21 T 29-03-2018 CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 SMART SM00287 111 173 6.9E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 SMART SM00287 52 110 22.0 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 Gene3D G3DSA:2.40.50.110 24 109 4.2E-7 T 29-03-2018 CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 Gene3D G3DSA:2.40.50.110 110 172 3.5E-15 T 29-03-2018 CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 Gene3D G3DSA:3.90.1720.10 216 340 4.6E-45 T 29-03-2018 CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 SUPERFAMILY SSF54001 214 339 2.13E-45 T 29-03-2018 CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 Pfam PF08239 Bacterial SH3 domain 121 170 1.9E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS00910 03eae441f7263e97cbd2eefd5b3eedbe 340 Pfam PF00877 NlpC/P60 family 231 337 1.0E-30 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS17100 4c1d7ffa0050b93a63f1a46906a7b2c9 356 Pfam PF00155 Aminotransferase class I and II 24 348 8.4E-42 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS17100 4c1d7ffa0050b93a63f1a46906a7b2c9 356 SUPERFAMILY SSF53383 7 355 8.16E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS17100 4c1d7ffa0050b93a63f1a46906a7b2c9 356 Gene3D G3DSA:3.40.640.10 48 238 2.1E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS17100 4c1d7ffa0050b93a63f1a46906a7b2c9 356 Gene3D G3DSA:3.90.1150.10 239 353 2.3E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 Gene3D G3DSA:3.40.50.1860 120 220 5.0E-12 T 29-03-2018 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 Gene3D G3DSA:3.40.50.1860 2 119 1.3E-24 T 29-03-2018 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 83 91 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 SUPERFAMILY SSF53681 120 228 9.81E-16 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 SUPERFAMILY SSF53681 4 115 2.62E-24 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 223 2.8E-34 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR56_RS09690 0e74b1daa725467b9870aaf0ef466de5 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 229 6.7E-36 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 Pfam PF13530 Sterol carrier protein domain 171 390 4.1E-42 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 SUPERFAMILY SSF55718 280 394 1.33E-21 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 Gene3D G3DSA:3.30.1050.10 270 388 4.1E-22 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 Gene3D G3DSA:3.40.630.30 132 269 4.8E-22 T 29-03-2018 CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 Pfam PF13527 Acetyltransferase (GNAT) domain 2 125 1.5E-34 T 29-03-2018 CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 Gene3D G3DSA:3.40.630.30 1 131 7.4E-12 T 29-03-2018 CWR56_RS12515 c333dd12c92b19ebecf903b421933799 394 SUPERFAMILY SSF55729 1 279 1.64E-69 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS15140 cc437e02a59828b331c34ebf6595879e 165 SMART SM01058 1 112 4.7E-6 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS15140 cc437e02a59828b331c34ebf6595879e 165 SUPERFAMILY SSF141259 2 55 3.4E-6 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS15140 cc437e02a59828b331c34ebf6595879e 165 Pfam PF02559 CarD-like/TRCF domain 2 110 1.1E-15 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 17 117 2.0E-25 T 29-03-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 SMART SM00478 122 285 2.1E-16 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 SUPERFAMILY SSF48150 112 285 2.97E-40 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 Gene3D G3DSA:1.10.1670.10 236 288 2.5E-13 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 118 262 1.2E-13 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 SUPERFAMILY SSF55945 6 111 7.53E-24 T 29-03-2018 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 Gene3D G3DSA:1.10.340.30 112 233 1.0E-33 T 29-03-2018 CWR56_RS00950 3035ae641a7792a0302fd9f869eccf3e 291 Gene3D G3DSA:3.30.310.40 15 98 1.6E-11 T 29-03-2018 CWR56_RS12945 a6f2cd68d9872ae25319f47a4894835d 116 Pfam PF03780 Asp23 family, cell envelope-related function 9 114 5.5E-31 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CWR56_RS18485 6d85cec431cbc07d9e90ad19eee91b99 135 Gene3D G3DSA:3.30.565.10 1 132 1.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18485 6d85cec431cbc07d9e90ad19eee91b99 135 SMART SM00387 36 133 0.002 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18485 6d85cec431cbc07d9e90ad19eee91b99 135 Pfam PF13581 Histidine kinase-like ATPase domain 11 129 2.3E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS18485 6d85cec431cbc07d9e90ad19eee91b99 135 SUPERFAMILY SSF55874 30 128 1.07E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS13180 bc8c4b9efe9810f21a9a5d27e735dcb3 116 Gene3D G3DSA:3.10.20.110 1 58 5.3E-14 T 29-03-2018 CWR56_RS13180 bc8c4b9efe9810f21a9a5d27e735dcb3 116 SUPERFAMILY SSF56988 1 70 4.45E-14 T 29-03-2018 CWR56_RS15905 b262ff03bad091ab20dd304fd4831a88 312 Pfam PF03547 Membrane transport protein 159 302 5.4E-14 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CWR56_RS15905 b262ff03bad091ab20dd304fd4831a88 312 Pfam PF03547 Membrane transport protein 9 157 6.2E-15 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CWR56_RS10830 135970b25f410fb9511c023039c9be08 150 Pfam PF04074 Domain of unknown function (DUF386) 1 147 3.3E-44 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family CWR56_RS10830 135970b25f410fb9511c023039c9be08 150 Gene3D G3DSA:2.60.120.370 1 150 1.2E-45 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family CWR56_RS10830 135970b25f410fb9511c023039c9be08 150 SUPERFAMILY SSF51197 1 149 7.69E-42 T 29-03-2018 CWR56_RS10830 135970b25f410fb9511c023039c9be08 150 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 149 6.5E-34 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 Gene3D G3DSA:3.40.630.10 2 270 9.1E-45 T 29-03-2018 CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 Pfam PF01546 Peptidase family M20/M25/M40 80 369 4.8E-10 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 Pfam PF07687 Peptidase dimerisation domain 176 265 1.7E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 PIRSF PIRSF037226 2 395 1.4E-119 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 SUPERFAMILY SSF55031 175 281 3.66E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 SUPERFAMILY SSF53187 288 383 1.23E-55 T 29-03-2018 CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 SUPERFAMILY SSF53187 10 188 1.23E-55 T 29-03-2018 CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 Gene3D G3DSA:3.40.630.10 308 395 2.3E-6 T 29-03-2018 CWR56_RS15480 7de286b737a25e1ea2edcb5bcb5db92d 395 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 25 338 1.7E-72 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS10615 42ec9f4a5c0338b0711339c14e64f319 349 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 235 325 2.7E-21 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CWR56_RS10615 42ec9f4a5c0338b0711339c14e64f319 349 SUPERFAMILY SSF52922 227 315 9.85E-22 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR56_RS10615 42ec9f4a5c0338b0711339c14e64f319 349 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 232 5.4E-45 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CWR56_RS10615 42ec9f4a5c0338b0711339c14e64f319 349 SUPERFAMILY SSF52518 3 193 2.94E-54 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS10615 42ec9f4a5c0338b0711339c14e64f319 349 Gene3D G3DSA:3.40.50.970 1 263 7.9E-50 T 29-03-2018 CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 425 440 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 SMART SM00382 358 503 2.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 Pfam PF00158 Sigma-54 interaction domain 340 505 1.1E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 SUPERFAMILY SSF55785 211 275 2.79E-7 T 29-03-2018 IPR000014 PAS domain CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 SMART SM00091 212 278 0.0015 T 29-03-2018 IPR000014 PAS domain CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 Gene3D G3DSA:3.30.450.20 210 334 5.9E-5 T 29-03-2018 CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 SUPERFAMILY SSF52540 348 564 2.06E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 Gene3D G3DSA:3.40.50.300 335 682 8.5E-40 T 29-03-2018 CWR56_RS13850 9cce4a722c56b2f244fbc1b555b4b86c 706 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 362 375 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS05725 15495160147f429405ca774e9f6c262f 130 Pfam PF04542 Sigma-70 region 2 35 104 4.8E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS05725 15495160147f429405ca774e9f6c262f 130 SUPERFAMILY SSF88946 10 103 1.73E-32 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS05725 15495160147f429405ca774e9f6c262f 130 Gene3D G3DSA:1.10.601.10 4 103 6.1E-31 T 29-03-2018 CWR56_RS05725 15495160147f429405ca774e9f6c262f 130 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 107 2.5E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS05725 15495160147f429405ca774e9f6c262f 130 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR56_RS12695 91b18c5bc8e304f99f008d18b6712462 126 SUPERFAMILY SSF55298 1 126 1.3E-51 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR56_RS12695 91b18c5bc8e304f99f008d18b6712462 126 Gene3D G3DSA:3.30.1330.40 1 126 1.9E-52 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR56_RS12695 91b18c5bc8e304f99f008d18b6712462 126 Pfam PF01042 Endoribonuclease L-PSP 9 125 6.8E-49 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CWR56_RS12695 91b18c5bc8e304f99f008d18b6712462 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 29-03-2018 IPR019897 RidA, conserved site CWR56_RS12695 91b18c5bc8e304f99f008d18b6712462 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 125 1.0E-57 T 29-03-2018 IPR006056 RidA family CWR56_RS14135 bd9753b7e70d94153209f23d0bee92f3 525 Gene3D G3DSA:1.20.1270.70 436 518 6.6E-4 T 29-03-2018 CWR56_RS14135 bd9753b7e70d94153209f23d0bee92f3 525 Pfam PF04122 Putative cell wall binding repeat 2 229 315 6.4E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14135 bd9753b7e70d94153209f23d0bee92f3 525 Pfam PF04122 Putative cell wall binding repeat 2 35 119 7.9E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14135 bd9753b7e70d94153209f23d0bee92f3 525 Pfam PF04122 Putative cell wall binding repeat 2 131 221 2.8E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS17615 be2d7c23e516df16040a3776ce01020d 237 Gene3D G3DSA:3.40.50.300 1 237 7.3E-50 T 29-03-2018 CWR56_RS17615 be2d7c23e516df16040a3776ce01020d 237 SMART SM00382 36 230 1.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS17615 be2d7c23e516df16040a3776ce01020d 237 SUPERFAMILY SSF52540 4 235 6.29E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17615 be2d7c23e516df16040a3776ce01020d 237 Pfam PF00005 ABC transporter 28 182 7.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS18000 31ba88b80bee4c816335b8562e308a49 312 Gene3D G3DSA:3.40.50.720 1 157 4.6E-10 T 29-03-2018 CWR56_RS18000 31ba88b80bee4c816335b8562e308a49 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 212 4.2E-14 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR56_RS18000 31ba88b80bee4c816335b8562e308a49 312 Gene3D G3DSA:3.90.25.10 158 311 4.4E-20 T 29-03-2018 CWR56_RS18000 31ba88b80bee4c816335b8562e308a49 312 SUPERFAMILY SSF51735 2 291 5.45E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 SUPERFAMILY SSF53187 3 78 3.02E-59 T 29-03-2018 CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 SUPERFAMILY SSF53187 160 343 3.02E-59 T 29-03-2018 CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 SUPERFAMILY SSF101821 68 168 1.08E-19 T 29-03-2018 CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 PIRSF PIRSF001123 1 346 2.5E-107 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 Pfam PF05343 M42 glutamyl aminopeptidase 43 327 1.2E-78 T 29-03-2018 IPR008007 Peptidase M42 CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 Gene3D G3DSA:2.40.30.40 68 149 3.7E-18 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CWR56_RS17180 5544a4426aa1f7f510e73afa95f25a7f 347 Gene3D G3DSA:3.40.630.10 155 345 4.3E-38 T 29-03-2018 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 SUPERFAMILY SSF56300 344 639 1.58E-46 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 Pfam PF00149 Calcineurin-like phosphoesterase 36 289 3.1E-6 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 Pfam PF00149 Calcineurin-like phosphoesterase 347 587 2.9E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 Gene3D G3DSA:3.60.21.10 344 641 9.4E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 Gene3D G3DSA:3.60.21.10 32 343 3.2E-50 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 PRINTS PR01607 Apyrase family signature 344 362 1.3E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 PRINTS PR01607 Apyrase family signature 570 593 1.3E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 PRINTS PR01607 Apyrase family signature 542 559 1.3E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 PRINTS PR01607 Apyrase family signature 602 622 1.3E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS03305 3d8822d62ccdf7530fc7e31cbf7f4c02 641 SUPERFAMILY SSF56300 31 342 7.97E-50 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS01815 9674dc354374dcd2d50e91dfeffe1b9a 385 Gene3D G3DSA:3.40.50.150 38 308 1.3E-16 T 29-03-2018 CWR56_RS01815 9674dc354374dcd2d50e91dfeffe1b9a 385 SUPERFAMILY SSF53335 154 266 8.67E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS01815 9674dc354374dcd2d50e91dfeffe1b9a 385 Pfam PF13679 Methyltransferase domain 158 293 4.9E-35 T 29-03-2018 IPR025714 Methyltransferase domain CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 437 449 5.5E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 319 5.5E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 5.5E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 5.5E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 5.5E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 SUPERFAMILY SSF51445 3 472 1.15E-144 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 Gene3D G3DSA:3.20.20.80 1 482 1.1E-137 T 29-03-2018 CWR56_RS15560 4b05f4cf16daaebc9b9a6615db23dac6 484 Pfam PF00232 Glycosyl hydrolase family 1 4 472 7.1E-120 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS02325 8210878719fd9eba6cba27cdcde9a743 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 7 18 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CWR56_RS02325 8210878719fd9eba6cba27cdcde9a743 338 SUPERFAMILY SSF102114 4 299 4.19E-44 T 29-03-2018 CWR56_RS02325 8210878719fd9eba6cba27cdcde9a743 338 Pfam PF04055 Radical SAM superfamily 7 156 3.6E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR56_RS02325 8210878719fd9eba6cba27cdcde9a743 338 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 234 317 4.3E-10 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CWR56_RS02325 8210878719fd9eba6cba27cdcde9a743 338 Gene3D G3DSA:3.20.20.70 2 305 1.1E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS02325 8210878719fd9eba6cba27cdcde9a743 338 Pfam PF13353 4Fe-4S single cluster domain 4 122 1.9E-10 T 29-03-2018 CWR56_RS09530 098955105dda58db9d01a23d61c58599 110 Pfam PF02627 Carboxymuconolactone decarboxylase family 22 105 8.5E-15 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CWR56_RS09530 098955105dda58db9d01a23d61c58599 110 SUPERFAMILY SSF69118 14 110 2.88E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWR56_RS09530 098955105dda58db9d01a23d61c58599 110 Gene3D G3DSA:1.20.1290.10 2 109 1.4E-15 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWR56_RS13520 790e7368ea4a58e2a74ad8ef2e7d23b5 319 Gene3D G3DSA:1.10.3720.10 3 302 1.2E-40 T 29-03-2018 CWR56_RS13520 790e7368ea4a58e2a74ad8ef2e7d23b5 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.2E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS13520 790e7368ea4a58e2a74ad8ef2e7d23b5 319 SUPERFAMILY SSF161098 90 296 7.19E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 360 373 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 Gene3D G3DSA:3.30.450.20 198 311 9.0E-5 T 29-03-2018 CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 Pfam PF00158 Sigma-54 interaction domain 338 503 9.9E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 423 438 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 SMART SM00382 356 500 2.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 SUPERFAMILY SSF52540 336 562 1.54E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS00815 5886485f75c9f2de7e60efb5afbe89ae 670 Gene3D G3DSA:3.40.50.300 312 556 2.6E-35 T 29-03-2018 CWR56_RS14915 c72d22be20928e98200aaaaaf2388a4a 341 SUPERFAMILY SSF81345 4 336 2.09E-73 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CWR56_RS14915 c72d22be20928e98200aaaaaf2388a4a 341 Gene3D G3DSA:1.10.3470.10 6 341 4.5E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS14915 c72d22be20928e98200aaaaaf2388a4a 341 Pfam PF01032 FecCD transport family 22 336 3.4E-84 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR56_RS05425 59b33bb9d18b220ea2ad5736845d5125 179 Pfam PF00583 Acetyltransferase (GNAT) family 56 151 3.4E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS05425 59b33bb9d18b220ea2ad5736845d5125 179 Gene3D G3DSA:3.40.630.30 10 178 2.1E-30 T 29-03-2018 CWR56_RS05425 59b33bb9d18b220ea2ad5736845d5125 179 SUPERFAMILY SSF55729 11 177 6.32E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 166 183 1.8E-27 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 97 113 1.8E-27 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 289 307 1.8E-27 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 427 442 1.8E-27 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 130 150 1.8E-27 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 333 349 1.8E-27 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 SUPERFAMILY SSF53187 240 460 1.63E-102 T 29-03-2018 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 SUPERFAMILY SSF53187 13 108 1.63E-102 T 29-03-2018 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 Gene3D G3DSA:3.40.630.10 176 463 2.0E-63 T 29-03-2018 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 Gene3D G3DSA:3.40.630.10 4 117 1.5E-23 T 29-03-2018 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 SUPERFAMILY SSF101821 109 239 2.56E-35 T 29-03-2018 CWR56_RS04955 78425a38d66959c192efb98127ab6613 464 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 33 460 2.7E-90 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Gene3D G3DSA:2.20.25.90 5 63 1.4E-14 T 29-03-2018 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 SMART SM00926 4 59 1.3E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 59 2.3E-10 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 SUPERFAMILY SSF53706 451 635 4.71E-128 T 29-03-2018 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 SUPERFAMILY SSF53706 10 404 4.71E-128 T 29-03-2018 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Gene3D G3DSA:3.40.50.740 325 598 4.7E-17 T 29-03-2018 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 SUPERFAMILY SSF50692 607 754 1.41E-19 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Gene3D G3DSA:3.40.228.10 149 324 3.4E-53 T 29-03-2018 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Gene3D G3DSA:2.40.40.20 631 755 5.5E-14 T 29-03-2018 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Pfam PF01568 Molydopterin dinucleotide binding domain 666 747 7.2E-13 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Pfam PF00384 Molybdopterin oxidoreductase 62 556 2.6E-42 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS03735 9f4f32d2507bc2cd04e76d416fd87cba 756 Gene3D G3DSA:3.40.50.740 64 148 1.2E-9 T 29-03-2018 CWR56_RS08360 f9dfc3c4b938e8f4ca9d0fdc803fb175 452 Pfam PF14501 GHKL domain 351 443 2.4E-21 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS08360 f9dfc3c4b938e8f4ca9d0fdc803fb175 452 SUPERFAMILY SSF55874 321 433 6.94E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08360 f9dfc3c4b938e8f4ca9d0fdc803fb175 452 Gene3D G3DSA:3.30.565.10 313 444 9.7E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08360 f9dfc3c4b938e8f4ca9d0fdc803fb175 452 Gene3D G3DSA:1.10.287.130 249 311 2.7E-11 T 29-03-2018 CWR56_RS02905 27ecc8c1e0e912b2d095bddce69d8a70 297 Pfam PF02517 CAAX protease self-immunity 130 235 1.6E-4 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 Gene3D G3DSA:3.20.20.80 1 481 1.8E-136 T 29-03-2018 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 Pfam PF00232 Glycosyl hydrolase family 1 3 471 3.8E-122 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 SUPERFAMILY SSF51445 2 468 2.39E-142 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 3.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 3.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 3.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 3.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15640 a77c205b794ea7f5be7109e17f564ce6 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 3.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 PIRSF PIRSF000089 9 338 1.2E-121 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 Gene3D G3DSA:3.40.50.1220 209 338 4.1E-57 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 277 303 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 SUPERFAMILY SSF52467 213 333 6.25E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 213 296 3.6E-36 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 Gene3D G3DSA:3.40.50.620 1 206 4.5E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 SUPERFAMILY SSF52402 11 208 6.21E-60 T 29-03-2018 CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 Pfam PF01012 Electron transfer flavoprotein domain 13 190 1.0E-50 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS01915 75dc8d47c71a45d8361ed106df57ad64 345 SMART SM00893 13 202 2.9E-59 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS08225 3e43aa4a71942b2212777b9ee014559e 359 SUPERFAMILY SSF160991 1 354 2.22E-119 T 29-03-2018 CWR56_RS08225 3e43aa4a71942b2212777b9ee014559e 359 Gene3D G3DSA:3.40.1610.10 2 218 1.3E-70 T 29-03-2018 IPR027479 Protein of unknown function DUF917, N-terminal CWR56_RS08225 3e43aa4a71942b2212777b9ee014559e 359 Pfam PF06032 Protein of unknown function (DUF917) 8 352 2.8E-123 T 29-03-2018 IPR010318 Protein of unknown function DUF917 CWR56_RS08225 3e43aa4a71942b2212777b9ee014559e 359 Gene3D G3DSA:2.40.390.10 219 343 1.1E-36 T 29-03-2018 IPR024071 Protein of unknown function DUF917, C-terminal CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 SMART SM00448 1 111 2.0E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 SUPERFAMILY SSF46894 118 220 1.08E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 SMART SM00862 142 219 2.4E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 SUPERFAMILY SSF52172 2 117 5.41E-34 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 Gene3D G3DSA:3.40.50.2300 1 117 1.3E-29 T 29-03-2018 CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 Gene3D G3DSA:1.10.10.10 118 223 6.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 Pfam PF00072 Response regulator receiver domain 4 111 1.5E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS09320 6c14a97ea0d84b08fd708a256cf0a97e 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 218 8.1E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS10715 30526592e75fdeda49a9792ece362bba 255 Gene3D G3DSA:3.20.20.70 1 253 7.2E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS10715 30526592e75fdeda49a9792ece362bba 255 ProSitePatterns PS01028 Dehydroquinase class I active site. 115 145 - T 29-03-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR56_RS10715 30526592e75fdeda49a9792ece362bba 255 SUPERFAMILY SSF51569 4 251 5.86E-84 T 29-03-2018 CWR56_RS10715 30526592e75fdeda49a9792ece362bba 255 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 18 246 2.6E-73 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR56_RS10715 30526592e75fdeda49a9792ece362bba 255 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 18 250 38.53 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR56_RS10715 30526592e75fdeda49a9792ece362bba 255 Pfam PF01487 Type I 3-dehydroquinase 20 247 5.1E-71 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR56_RS06470 78d7b97aca7aed2c624468b9b73bb569 406 Pfam PF01566 Natural resistance-associated macrophage protein 45 374 2.2E-24 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Gene3D G3DSA:2.40.50.110 23 98 5.0E-19 T 29-03-2018 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Gene3D G3DSA:2.40.50.110 99 173 1.3E-19 T 29-03-2018 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Gene3D G3DSA:2.40.50.110 174 253 1.6E-20 T 29-03-2018 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 SUPERFAMILY SSF50044 64 100 1.5E-6 T 29-03-2018 IPR001452 SH3 domain GO:0005515 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Gene3D G3DSA:3.90.1720.10 269 396 5.2E-43 T 29-03-2018 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 SUPERFAMILY SSF54001 265 395 2.94E-44 T 29-03-2018 CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 SMART SM00287 192 254 7.0E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 SMART SM00287 113 175 2.0E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 SMART SM00287 38 100 2.0E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Pfam PF08239 Bacterial SH3 domain 201 250 1.2E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Pfam PF08239 Bacterial SH3 domain 47 96 1.4E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Pfam PF08239 Bacterial SH3 domain 121 171 1.5E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CWR56_RS12125 223c781a8c19544cbd1ac55187cd44e4 396 Pfam PF00877 NlpC/P60 family 284 394 4.7E-30 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CWR56_RS01235 76c27391cd4d6ae2392a2c765e6acacb 314 SUPERFAMILY SSF51735 1 296 2.63E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS01235 76c27391cd4d6ae2392a2c765e6acacb 314 Gene3D G3DSA:3.40.50.720 130 226 7.9E-5 T 29-03-2018 CWR56_RS01235 76c27391cd4d6ae2392a2c765e6acacb 314 Gene3D G3DSA:3.30.1780.10 1 129 2.5E-20 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CWR56_RS01235 76c27391cd4d6ae2392a2c765e6acacb 314 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 294 4.3E-27 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 SUPERFAMILY SSF55031 167 269 1.12E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 Pfam PF07687 Peptidase dimerisation domain 167 257 7.4E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 SUPERFAMILY SSF53187 278 371 1.26E-61 T 29-03-2018 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 SUPERFAMILY SSF53187 3 178 1.26E-61 T 29-03-2018 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 Gene3D G3DSA:3.40.630.10 1 269 5.3E-46 T 29-03-2018 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 Gene3D G3DSA:3.40.630.10 291 378 1.5E-9 T 29-03-2018 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 335 1.0E-67 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 Pfam PF01546 Peptidase family M20/M25/M40 79 335 7.9E-11 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS12220 6fd8a9c801a82174a39b64a42d776f69 378 PIRSF PIRSF037226 1 378 6.8E-138 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CWR56_RS15835 bc42e59b8927f98e4f5bff3f73b4a677 71 Pfam PF12668 Protein of unknown function (DUF3791) 7 68 8.0E-23 T 29-03-2018 IPR024269 Protein of unknown function DUF3791 CWR56_RS16260 a8a079f222a6984123deecd1e9a8786a 211 Gene3D G3DSA:2.40.50.140 2 99 6.6E-7 T 29-03-2018 CWR56_RS16260 a8a079f222a6984123deecd1e9a8786a 211 Gene3D G3DSA:2.40.50.140 100 207 2.2E-26 T 29-03-2018 CWR56_RS16260 a8a079f222a6984123deecd1e9a8786a 211 Pfam PF00436 Single-strand binding protein family 108 203 5.2E-16 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWR56_RS16260 a8a079f222a6984123deecd1e9a8786a 211 SUPERFAMILY SSF50249 9 206 1.41E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS16440 03096b8bf6b3f0e132f0434a372684ea 594 SUPERFAMILY SSF55486 11 574 1.44E-120 T 29-03-2018 CWR56_RS16440 03096b8bf6b3f0e132f0434a372684ea 594 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 5 592 3.6E-205 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CWR56_RS16440 03096b8bf6b3f0e132f0434a372684ea 594 Pfam PF01432 Peptidase family M3 201 581 4.6E-68 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWR56_RS16440 03096b8bf6b3f0e132f0434a372684ea 594 Gene3D G3DSA:1.10.1370.10 113 586 2.0E-37 T 29-03-2018 CWR56_RS16440 03096b8bf6b3f0e132f0434a372684ea 594 Pfam PF08439 Oligopeptidase F 112 180 3.9E-21 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CWR56_RS01480 a9738696eceb87d13676e7870fc2464c 287 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 24 287 1.4E-91 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWR56_RS12080 c784eaa019f688f195fd75b9bab3a494 338 Gene3D G3DSA:1.10.3810.10 140 331 3.4E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CWR56_RS12080 c784eaa019f688f195fd75b9bab3a494 338 Pfam PF00912 Transglycosylase 149 313 3.5E-59 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CWR56_RS12080 c784eaa019f688f195fd75b9bab3a494 338 SUPERFAMILY SSF53955 151 332 2.81E-58 T 29-03-2018 IPR023346 Lysozyme-like domain CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 Pfam PF00005 ABC transporter 18 184 1.8E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 Pfam PF00005 ABC transporter 336 467 8.7E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 Gene3D G3DSA:3.40.50.300 1 286 1.0E-55 T 29-03-2018 CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 SMART SM00382 26 237 5.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 SUPERFAMILY SSF52540 8 238 8.75E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 Pfam PF12848 ABC transporter 224 303 2.0E-21 T 29-03-2018 IPR032781 ABC-transporter extension domain CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 SUPERFAMILY SSF52540 295 513 1.3E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09915 751450b2536d3abf1f7816c28f9f52b9 541 Gene3D G3DSA:3.40.50.300 287 541 3.6E-32 T 29-03-2018 CWR56_RS13105 41587f17df0c318e361fbc9a751b19ed 344 Pfam PF01212 Beta-eliminating lyase 5 286 8.8E-94 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CWR56_RS13105 41587f17df0c318e361fbc9a751b19ed 344 PIRSF PIRSF017617 1 343 8.2E-149 T 29-03-2018 IPR023603 Threonine aldolase CWR56_RS13105 41587f17df0c318e361fbc9a751b19ed 344 SUPERFAMILY SSF53383 4 340 1.22E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS13105 41587f17df0c318e361fbc9a751b19ed 344 Gene3D G3DSA:3.90.1150.10 248 342 2.2E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS13105 41587f17df0c318e361fbc9a751b19ed 344 Gene3D G3DSA:3.40.640.10 1 247 1.4E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS04690 8bd38c170b97991cd8fb8b54613f7fde 282 Pfam PF00990 Diguanylate cyclase, GGDEF domain 130 260 4.0E-17 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04690 8bd38c170b97991cd8fb8b54613f7fde 282 SUPERFAMILY SSF55073 135 262 4.55E-13 T 29-03-2018 IPR029787 Nucleotide cyclase CWR56_RS04690 8bd38c170b97991cd8fb8b54613f7fde 282 Gene3D G3DSA:3.30.70.270 122 270 6.2E-15 T 29-03-2018 CWR56_RS04690 8bd38c170b97991cd8fb8b54613f7fde 282 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 128 258 1.0E-10 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS04690 8bd38c170b97991cd8fb8b54613f7fde 282 SMART SM00267 118 271 2.4E-5 T 29-03-2018 IPR000160 GGDEF domain CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 Pfam PF00188 Cysteine-rich secretory protein family 401 525 6.1E-12 T 29-03-2018 IPR014044 CAP domain CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 Gene3D G3DSA:2.60.40.10 304 383 1.7E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 Pfam PF04122 Putative cell wall binding repeat 2 33 116 1.7E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 Pfam PF04122 Putative cell wall binding repeat 2 128 208 1.3E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 Pfam PF04122 Putative cell wall binding repeat 2 218 284 2.9E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 SUPERFAMILY SSF55797 397 526 7.32E-14 T 29-03-2018 IPR014044 CAP domain CWR56_RS14180 62089badd354ddf2ef8d177d9b812419 533 Gene3D G3DSA:3.40.33.10 387 523 3.5E-9 T 29-03-2018 IPR014044 CAP domain CWR56_RS10730 bf3597e6e91ee0a63e1621f697205c57 206 Gene3D G3DSA:1.10.10.10 135 205 1.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10730 bf3597e6e91ee0a63e1621f697205c57 206 Gene3D G3DSA:2.60.120.10 7 134 3.5E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS10730 bf3597e6e91ee0a63e1621f697205c57 206 Pfam PF00027 Cyclic nucleotide-binding domain 18 103 1.0E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR56_RS10730 bf3597e6e91ee0a63e1621f697205c57 206 SUPERFAMILY SSF46785 135 199 1.52E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS10730 bf3597e6e91ee0a63e1621f697205c57 206 SUPERFAMILY SSF51206 6 130 1.22E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CWR56_RS14925 76d50fd0b0240a35fe303eb033cfa5fd 131 Gene3D G3DSA:3.30.70.1290 1 131 2.6E-23 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS14925 76d50fd0b0240a35fe303eb033cfa5fd 131 SMART SM01321 10 129 3.1E-41 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS14925 76d50fd0b0240a35fe303eb033cfa5fd 131 SUPERFAMILY SSF143422 1 131 1.57E-46 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS14925 76d50fd0b0240a35fe303eb033cfa5fd 131 Pfam PF01797 Transposase IS200 like 11 129 4.5E-41 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWR56_RS05540 341e440a94a0e01dde3714925936db0d 352 SUPERFAMILY SSF50494 242 331 4.15E-7 T 29-03-2018 IPR009003 Peptidase S1, PA clan CWR56_RS05540 341e440a94a0e01dde3714925936db0d 352 Gene3D G3DSA:2.30.42.10 60 153 4.4E-11 T 29-03-2018 CWR56_RS05540 341e440a94a0e01dde3714925936db0d 352 Pfam PF05580 SpoIVB peptidase S55 139 350 2.4E-74 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB CWR56_RS05540 341e440a94a0e01dde3714925936db0d 352 SUPERFAMILY SSF50156 40 130 4.93E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS05540 341e440a94a0e01dde3714925936db0d 352 Gene3D G3DSA:2.40.10.10 242 352 2.4E-4 T 29-03-2018 CWR56_RS01445 1eeea25c4b50f29707d1b912ff59e685 247 Gene3D G3DSA:3.20.20.140 7 236 7.5E-32 T 29-03-2018 CWR56_RS01445 1eeea25c4b50f29707d1b912ff59e685 247 SUPERFAMILY SSF89550 5 227 5.62E-51 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS01445 1eeea25c4b50f29707d1b912ff59e685 247 SMART SM00481 5 79 1.8E-7 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 SUPERFAMILY SSF55031 201 316 4.06E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 Gene3D G3DSA:3.40.630.10 284 415 1.1E-11 T 29-03-2018 CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 Gene3D G3DSA:3.40.630.10 1 283 3.5E-33 T 29-03-2018 CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 PIRSF PIRSF037226 1 425 5.5E-78 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 SUPERFAMILY SSF53187 317 405 7.68E-45 T 29-03-2018 CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 SUPERFAMILY SSF53187 9 216 7.68E-45 T 29-03-2018 CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 380 3.2E-50 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS02420 6ade8d7e8d5b741f13ae243dafaeeb35 436 Pfam PF07687 Peptidase dimerisation domain 200 278 3.2E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS03860 b57227f81811d12992f0bd05e739f576 147 Pfam PF00293 NUDIX domain 8 119 2.9E-8 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS03860 b57227f81811d12992f0bd05e739f576 147 Gene3D G3DSA:3.90.79.10 2 142 1.2E-13 T 29-03-2018 CWR56_RS03860 b57227f81811d12992f0bd05e739f576 147 SUPERFAMILY SSF55811 2 125 3.25E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS15095 93407324c8e00d94d6cfe121d0390984 199 SUPERFAMILY SSF53697 2 195 3.8E-49 T 29-03-2018 CWR56_RS15095 93407324c8e00d94d6cfe121d0390984 199 Gene3D G3DSA:3.40.50.10490 2 196 6.7E-51 T 29-03-2018 CWR56_RS15095 93407324c8e00d94d6cfe121d0390984 199 Pfam PF01380 SIS domain 37 165 1.1E-26 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS15430 f608c3de7e0df7410fab285dd171ceba 475 Gene3D G3DSA:3.30.1360.60 390 466 4.8E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15430 f608c3de7e0df7410fab285dd171ceba 475 Pfam PF02378 Phosphotransferase system, EIIC 9 299 1.6E-48 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15430 f608c3de7e0df7410fab285dd171ceba 475 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 360 452 7.1E-15 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS15430 f608c3de7e0df7410fab285dd171ceba 475 Pfam PF00367 phosphotransferase system, EIIB 394 426 3.9E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15430 f608c3de7e0df7410fab285dd171ceba 475 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 405 422 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR56_RS15430 f608c3de7e0df7410fab285dd171ceba 475 SUPERFAMILY SSF55604 392 464 2.88E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR56_RS01140 5861173f1512d8dd6ce6584de95f0c9f 222 Pfam PF01464 Transglycosylase SLT domain 99 193 9.9E-26 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CWR56_RS01140 5861173f1512d8dd6ce6584de95f0c9f 222 Gene3D G3DSA:1.10.530.10 44 222 6.6E-41 T 29-03-2018 CWR56_RS01140 5861173f1512d8dd6ce6584de95f0c9f 222 SUPERFAMILY SSF53955 92 221 2.82E-39 T 29-03-2018 IPR023346 Lysozyme-like domain CWR56_RS17130 f1054f1369f0ed29025aef2f06e028a2 186 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 184 9.4E-60 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17130 f1054f1369f0ed29025aef2f06e028a2 186 Gene3D G3DSA:3.40.50.300 19 185 9.8E-59 T 29-03-2018 CWR56_RS17130 f1054f1369f0ed29025aef2f06e028a2 186 SUPERFAMILY SSF52540 4 185 1.13E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17130 f1054f1369f0ed29025aef2f06e028a2 186 PIRSF PIRSF006135 3 186 1.7E-59 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CWR56_RS17130 f1054f1369f0ed29025aef2f06e028a2 186 Gene3D G3DSA:3.40.50.300 1 18 0.23 T 29-03-2018 CWR56_RS07630 befd51a31287793527ba7e952fb40752 118 SMART SM00345 15 76 2.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS07630 befd51a31287793527ba7e952fb40752 118 Gene3D G3DSA:1.10.10.10 7 70 2.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07630 befd51a31287793527ba7e952fb40752 118 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 58 4.3E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS07630 befd51a31287793527ba7e952fb40752 118 SUPERFAMILY SSF46785 5 76 3.33E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04695 48954ddfd86637d114efaee02423ef24 554 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 233 467 4.5E-61 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CWR56_RS04695 48954ddfd86637d114efaee02423ef24 554 Gene3D G3DSA:3.20.20.370 186 498 1.4E-18 T 29-03-2018 CWR56_RS04695 48954ddfd86637d114efaee02423ef24 554 SUPERFAMILY SSF88713 247 384 9.21E-8 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS04695 48954ddfd86637d114efaee02423ef24 554 SUPERFAMILY SSF88713 414 484 9.21E-8 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS14495 5c5257f685ab8a33f22018dad10af129 382 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 129 352 1.5E-20 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CWR56_RS14495 5c5257f685ab8a33f22018dad10af129 382 PIRSF PIRSF500216 2 382 9.4E-124 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB CWR56_RS14495 5c5257f685ab8a33f22018dad10af129 382 PIRSF PIRSF016636 1 380 3.0E-76 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CWR56_RS14495 5c5257f685ab8a33f22018dad10af129 382 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 5 381 7.7E-157 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB CWR56_RS09050 731586392eb04873cd57b7ef4552cee6 376 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 368 1.4E-115 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWR56_RS09050 731586392eb04873cd57b7ef4552cee6 376 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 154 182 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWR56_RS09050 731586392eb04873cd57b7ef4552cee6 376 Gene3D G3DSA:3.40.50.1970 1 165 3.9E-44 T 29-03-2018 CWR56_RS09050 731586392eb04873cd57b7ef4552cee6 376 SUPERFAMILY SSF56796 3 374 8.5E-120 T 29-03-2018 CWR56_RS09050 731586392eb04873cd57b7ef4552cee6 376 Gene3D G3DSA:1.20.1090.10 166 376 2.9E-65 T 29-03-2018 CWR56_RS08300 9d56f0795a5c8b76ddd92bbd8242e0de 383 Pfam PF13527 Acetyltransferase (GNAT) domain 5 130 1.3E-23 T 29-03-2018 CWR56_RS08300 9d56f0795a5c8b76ddd92bbd8242e0de 383 SUPERFAMILY SSF55729 1 252 1.15E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS08300 9d56f0795a5c8b76ddd92bbd8242e0de 383 Gene3D G3DSA:3.40.630.30 1 136 3.4E-9 T 29-03-2018 CWR56_RS08300 9d56f0795a5c8b76ddd92bbd8242e0de 383 Gene3D G3DSA:3.40.630.30 137 242 0.12 T 29-03-2018 CWR56_RS02520 692d449ea25ce088fc2bb6d23c18fbf8 460 Pfam PF05569 BlaR1 peptidase M56 4 296 1.2E-44 T 29-03-2018 IPR008756 Peptidase M56 CWR56_RS16705 ed2b340a0d90073317cbfc4ba18bbcd1 277 Gene3D G3DSA:1.50.10.20 119 235 4.8E-5 T 29-03-2018 CWR56_RS16705 ed2b340a0d90073317cbfc4ba18bbcd1 277 SUPERFAMILY SSF48239 12 206 1.37E-19 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CWR56_RS16705 ed2b340a0d90073317cbfc4ba18bbcd1 277 Gene3D G3DSA:1.50.10.20 10 118 2.3E-9 T 29-03-2018 CWR56_RS08385 9665e55753f716307531bc8884266ee6 329 Pfam PF00962 Adenosine/AMP deaminase 4 325 1.3E-74 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CWR56_RS08385 9665e55753f716307531bc8884266ee6 329 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 5 327 4.5E-94 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CWR56_RS08385 9665e55753f716307531bc8884266ee6 329 Gene3D G3DSA:3.20.20.140 1 329 1.1E-76 T 29-03-2018 CWR56_RS08385 9665e55753f716307531bc8884266ee6 329 Hamap MF_00540 Adenosine deaminase [add]. 2 329 52.396 T 29-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 CWR56_RS08385 9665e55753f716307531bc8884266ee6 329 SUPERFAMILY SSF51556 3 325 9.08E-81 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS04290 ac5a84caacb923fb87c42d9df9f4e283 340 Pfam PF04392 ABC transporter substrate binding protein 46 328 1.4E-88 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CWR56_RS04290 ac5a84caacb923fb87c42d9df9f4e283 340 SUPERFAMILY SSF53822 46 227 6.48E-12 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS04290 ac5a84caacb923fb87c42d9df9f4e283 340 Gene3D G3DSA:3.40.50.2300 43 164 3.5E-20 T 29-03-2018 CWR56_RS04290 ac5a84caacb923fb87c42d9df9f4e283 340 Gene3D G3DSA:3.40.50.2300 165 305 5.6E-18 T 29-03-2018 CWR56_RS07905 bc5a2fd42ba1c3112d21c2314b45f092 485 Gene3D G3DSA:3.40.640.10 82 343 9.9E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS07905 bc5a2fd42ba1c3112d21c2314b45f092 485 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 6 484 59.036 T 29-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CWR56_RS07905 bc5a2fd42ba1c3112d21c2314b45f092 485 Gene3D G3DSA:3.90.1150.10 344 469 5.3E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS07905 bc5a2fd42ba1c3112d21c2314b45f092 485 Pfam PF02347 Glycine cleavage system P-protein 27 368 1.7E-11 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CWR56_RS07905 bc5a2fd42ba1c3112d21c2314b45f092 485 SUPERFAMILY SSF53383 27 482 2.54E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS16760 d94c7512bca632d9497a3b83a6d6c95e 92 SUPERFAMILY SSF46689 1 89 1.18E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS16760 d94c7512bca632d9497a3b83a6d6c95e 92 Gene3D G3DSA:1.10.10.60 45 92 2.5E-8 T 29-03-2018 CWR56_RS16760 d94c7512bca632d9497a3b83a6d6c95e 92 Pfam PF08765 Mor transcription activator family 12 90 3.2E-6 T 29-03-2018 IPR014875 Mor transcription activator CWR56_RS18870 a574f427413dfa71c730af6adf9ccde2 364 SUPERFAMILY SSF88723 171 297 1.86E-25 T 29-03-2018 IPR029060 PIN domain-like CWR56_RS18870 a574f427413dfa71c730af6adf9ccde2 364 Pfam PF13638 PIN domain 172 286 3.1E-5 T 29-03-2018 IPR002716 PIN domain CWR56_RS18870 a574f427413dfa71c730af6adf9ccde2 364 Gene3D G3DSA:3.40.50.1010 168 300 1.3E-28 T 29-03-2018 IPR029060 PIN domain-like CWR56_RS18870 a574f427413dfa71c730af6adf9ccde2 364 SMART SM00670 169 276 6.3E-13 T 29-03-2018 IPR002716 PIN domain CWR56_RS15070 c434845cc2f8fdbf44e784ba5666d269 466 Gene3D G3DSA:2.160.20.10 8 434 6.5E-22 T 29-03-2018 IPR012334 Pectin lyase fold CWR56_RS15070 c434845cc2f8fdbf44e784ba5666d269 466 Pfam PF12708 Pectate lyase superfamily protein 13 219 3.4E-36 T 29-03-2018 IPR024535 Pectate lyase superfamily protein CWR56_RS15070 c434845cc2f8fdbf44e784ba5666d269 466 SUPERFAMILY SSF51126 10 325 1.3E-27 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CWR56_RS12185 39fbcae703085a0e3c117402c7769473 118 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 7 115 5.0E-16 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS12185 39fbcae703085a0e3c117402c7769473 118 Gene3D G3DSA:2.40.33.40 1 117 1.6E-32 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS12185 39fbcae703085a0e3c117402c7769473 118 SUPERFAMILY SSF141530 1 117 3.92E-31 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS12185 39fbcae703085a0e3c117402c7769473 118 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 2 115 4.6E-33 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS01835 7101503f7437db35075c88a362edaf3f 310 Gene3D G3DSA:3.40.630.50 8 203 6.5E-32 T 29-03-2018 CWR56_RS01835 7101503f7437db35075c88a362edaf3f 310 Gene3D G3DSA:3.40.50.10700 206 303 5.3E-19 T 29-03-2018 CWR56_RS01835 7101503f7437db35075c88a362edaf3f 310 SUPERFAMILY SSF142535 15 308 4.19E-56 T 29-03-2018 CWR56_RS01835 7101503f7437db35075c88a362edaf3f 310 Pfam PF04414 D-aminoacyl-tRNA deacylase 81 295 5.6E-42 T 29-03-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 CWR56_RS14030 3a96dc23c893b168522506cb2233ca4e 321 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 72 231 1.8E-29 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR56_RS14030 3a96dc23c893b168522506cb2233ca4e 321 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 72 231 1.7E-39 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR56_RS01635 6b297d8d36d06bfb990fae7c8fdf435d 202 Pfam PF09335 SNARE associated Golgi protein 29 155 4.7E-17 T 29-03-2018 IPR032816 SNARE associated Golgi protein CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Pfam PF01757 Acyltransferase family 8 328 1.4E-24 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 SMART SM01005 583 712 7.3E-55 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Hamap MF_01201 Alanine racemase. 343 712 30.502 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Gene3D G3DSA:2.40.37.10 566 711 2.6E-47 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Pfam PF01168 Alanine racemase, N-terminal domain 350 566 4.1E-58 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Pfam PF00842 Alanine racemase, C-terminal domain 583 708 8.4E-36 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Gene3D G3DSA:1.20.1250.20 71 344 3.6E-4 T 29-03-2018 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 599 614 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 541 568 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 369 385 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 405 423 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 462 474 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 694 707 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 495 506 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 PRINTS PR00992 Alanine racemase signature 616 631 4.0E-38 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 Gene3D G3DSA:3.20.20.10 345 565 2.3E-41 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 TIGRFAM TIGR00492 alr: alanine racemase 345 709 6.5E-101 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 SUPERFAMILY SSF51419 350 584 9.45E-59 T 29-03-2018 IPR029066 PLP-binding barrel CWR56_RS07740 ba579505b88987076da9dd49d7bcc18a 712 SUPERFAMILY SSF50621 576 708 1.74E-39 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 448 1.0E-58 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 504 172.012 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 Pfam PF13500 AAA domain 3 230 1.3E-21 T 29-03-2018 CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 SUPERFAMILY SSF52317 191 403 2.75E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 Gene3D G3DSA:3.40.50.300 2 240 2.3E-48 T 29-03-2018 CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 499 3.5E-170 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 Gene3D G3DSA:3.40.50.880 250 501 1.9E-25 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS17115 bac587c1a754be8c84330fea4f302294 504 SUPERFAMILY SSF52540 4 229 1.78E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10045 c1c3a2359f7313e05dc85bb89fc8a149 422 Pfam PF10117 McrBC 5-methylcytosine restriction system component 54 374 8.2E-86 T 29-03-2018 IPR019292 5-methylcytosine restriction system component CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 Gene3D G3DSA:3.40.50.2000 480 796 1.7E-124 T 29-03-2018 CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 SUPERFAMILY SSF53756 5 810 1.73E-292 T 29-03-2018 CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 PIRSF PIRSF000460 3 812 2.5E-210 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 Gene3D G3DSA:3.40.50.2000 3 479 1.4E-179 T 29-03-2018 CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 Pfam PF00343 Carbohydrate phosphorylase 97 809 0.0 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 13 809 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWR56_RS04350 185e0196c5947abfc57ae88a9ba85f69 813 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 655 667 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWR56_RS10220 914b5a3b0f46d3eebe1dd680b059201d 174 SUPERFAMILY SSF55729 6 168 3.54E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS10220 914b5a3b0f46d3eebe1dd680b059201d 174 Pfam PF00583 Acetyltransferase (GNAT) family 53 144 1.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS10220 914b5a3b0f46d3eebe1dd680b059201d 174 Gene3D G3DSA:3.40.630.30 5 171 1.5E-33 T 29-03-2018 CWR56_RS05200 115f48add9bd8597c56a9e1c6f0df7ef 299 Pfam PF04085 rod shape-determining protein MreC 138 293 1.1E-36 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWR56_RS05200 115f48add9bd8597c56a9e1c6f0df7ef 299 Gene3D G3DSA:1.20.5.340 6 136 0.0014 T 29-03-2018 CWR56_RS05200 115f48add9bd8597c56a9e1c6f0df7ef 299 PIRSF PIRSF038471 8 299 3.3E-84 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWR56_RS05200 115f48add9bd8597c56a9e1c6f0df7ef 299 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 67 296 2.2E-28 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWR56_RS09255 ee1c39f551a0ebe4def98aa688563fc4 82 SUPERFAMILY SSF54593 16 71 6.05E-9 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS09255 ee1c39f551a0ebe4def98aa688563fc4 82 Gene3D G3DSA:3.10.180.10 3 80 1.5E-9 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS00410 ea33a1acc2c118a34513354b8fd8e735 783 Pfam PF03477 ATP cone domain 4 97 3.4E-17 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWR56_RS00410 ea33a1acc2c118a34513354b8fd8e735 783 SUPERFAMILY SSF51998 131 272 1.16E-153 T 29-03-2018 CWR56_RS00410 ea33a1acc2c118a34513354b8fd8e735 783 SUPERFAMILY SSF51998 326 763 1.16E-153 T 29-03-2018 CWR56_RS00410 ea33a1acc2c118a34513354b8fd8e735 783 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 126 782 5.1E-213 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CWR56_RS00410 ea33a1acc2c118a34513354b8fd8e735 783 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 310 782 2.3E-149 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CWR56_RS00410 ea33a1acc2c118a34513354b8fd8e735 783 Gene3D G3DSA:3.20.70.20 131 764 2.8E-204 T 29-03-2018 CWR56_RS03655 0700dee787916f543552b77af5c962ae 383 SUPERFAMILY SSF53383 3 372 6.93E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS03655 0700dee787916f543552b77af5c962ae 383 PIRSF PIRSF005572 1 380 1.9E-122 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR56_RS03655 0700dee787916f543552b77af5c962ae 383 Pfam PF00266 Aminotransferase class-V 3 361 2.6E-83 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS03655 0700dee787916f543552b77af5c962ae 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWR56_RS03655 0700dee787916f543552b77af5c962ae 383 Gene3D G3DSA:3.40.640.10 12 257 7.1E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS03655 0700dee787916f543552b77af5c962ae 383 Gene3D G3DSA:3.90.1150.10 264 380 1.2E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 PIRSF PIRSF000808 1 315 3.4E-72 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 84 162 6.9E-12 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 SUPERFAMILY SSF54197 162 313 2.01E-22 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 Gene3D G3DSA:3.30.428.10 37 150 2.7E-28 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 5 285 5.1E-35 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 Gene3D G3DSA:3.30.428.10 151 314 1.9E-19 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 SUPERFAMILY SSF54197 1 163 1.1E-39 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CWR56_RS06225 04a6ef665d0741967d7584434d7d548d 316 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 175 299 2.7E-7 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CWR56_RS08000 9e627e04698cb845f9b7f8247f9b8d28 110 SUPERFAMILY SSF46785 12 108 2.58E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS08000 9e627e04698cb845f9b7f8247f9b8d28 110 Pfam PF01638 HxlR-like helix-turn-helix 22 108 9.2E-28 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS08000 9e627e04698cb845f9b7f8247f9b8d28 110 Gene3D G3DSA:1.10.10.10 20 109 3.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 Gene3D G3DSA:3.40.1830.10 4 174 7.4E-64 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 Pfam PF02073 Thermophilic metalloprotease (M29) 5 407 3.8E-179 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 SUPERFAMILY SSF144052 4 408 2.88E-151 T 29-03-2018 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS17955 19d31158db3f784b4991c938f497fa10 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 1.3E-68 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR56_RS11285 a20f37e332e6d36ca08f94f0cc64d718 228 SUPERFAMILY SSF53639 3 217 1.14E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11285 a20f37e332e6d36ca08f94f0cc64d718 228 Gene3D G3DSA:3.40.225.10 1 227 7.5E-56 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11285 a20f37e332e6d36ca08f94f0cc64d718 228 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 194 1.9E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11285 a20f37e332e6d36ca08f94f0cc64d718 228 SMART SM01007 7 195 2.4E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWR56_RS11285 a20f37e332e6d36ca08f94f0cc64d718 228 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 2 227 7.9E-120 T 29-03-2018 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 CWR56_RS02875 2b0657f57da0521a3f4a7d07887efcdc 703 Pfam PF02687 FtsX-like permease family 86 180 1.7E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS02875 2b0657f57da0521a3f4a7d07887efcdc 703 Gene3D G3DSA:1.20.1250.20 96 257 0.07 T 29-03-2018 CWR56_RS02875 2b0657f57da0521a3f4a7d07887efcdc 703 Gene3D G3DSA:1.20.1250.20 268 693 0.14 T 29-03-2018 CWR56_RS02875 2b0657f57da0521a3f4a7d07887efcdc 703 Gene3D G3DSA:1.20.1250.20 12 95 0.035 T 29-03-2018 CWR56_RS02875 2b0657f57da0521a3f4a7d07887efcdc 703 PIRSF PIRSF018968 1 535 1.1E-35 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR56_RS02875 2b0657f57da0521a3f4a7d07887efcdc 703 PIRSF PIRSF018968 541 702 5.1E-4 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR56_RS14150 f3c7b9c1d4c8ce2f5fceab4a6503f4a0 710 Pfam PF04122 Putative cell wall binding repeat 2 131 221 6.5E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14150 f3c7b9c1d4c8ce2f5fceab4a6503f4a0 710 Pfam PF04122 Putative cell wall binding repeat 2 229 316 1.1E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14150 f3c7b9c1d4c8ce2f5fceab4a6503f4a0 710 Pfam PF04122 Putative cell wall binding repeat 2 34 119 1.1E-12 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04230 95c56fdbc8371181fcedef348a2f18e7 108 Gene3D G3DSA:3.40.50.2300 1 108 2.0E-28 T 29-03-2018 CWR56_RS04230 95c56fdbc8371181fcedef348a2f18e7 108 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 99 1.2E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS04230 95c56fdbc8371181fcedef348a2f18e7 108 SUPERFAMILY SSF52794 1 107 1.75E-22 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS09750 afc0eb55a13151362bfa6f2f72ddb1f0 207 Gene3D G3DSA:3.40.50.300 1 200 9.6E-11 T 29-03-2018 CWR56_RS09750 afc0eb55a13151362bfa6f2f72ddb1f0 207 Pfam PF13189 Cytidylate kinase-like family 3 183 1.6E-42 T 29-03-2018 IPR026865 Cytidylate kinase-like family KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR56_RS05855 910e48bcbfb8be52628ab1dc10d641f3 165 SMART SM01058 1 112 9.6E-14 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS05855 910e48bcbfb8be52628ab1dc10d641f3 165 SUPERFAMILY SSF141259 1 67 1.44E-9 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS05855 910e48bcbfb8be52628ab1dc10d641f3 165 Pfam PF02559 CarD-like/TRCF domain 2 111 2.7E-13 T 29-03-2018 IPR003711 CarD-like/TRCF domain CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 ProSitePatterns PS00855 Signal peptidases II signature. 91 103 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 Pfam PF01252 Signal peptidase (SPase) II 6 142 1.3E-36 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 147 16.034 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 TIGRFAM TIGR00077 lspA: signal peptidase II 2 146 1.3E-32 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.6E-15 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 88 103 1.6E-15 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS13135 1be689ffb98bd7c6940e3d70013a3637 148 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 122 138 1.6E-15 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR56_RS01005 6a73e7ba0058fdfdc636a206feef73a6 173 Pfam PF02417 Chromate transporter 1 169 2.6E-38 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CWR56_RS09325 422168a7791f7b683945ee5b07297b97 345 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 244 255 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS09325 422168a7791f7b683945ee5b07297b97 345 Gene3D G3DSA:3.30.70.20 234 302 8.5E-8 T 29-03-2018 CWR56_RS09325 422168a7791f7b683945ee5b07297b97 345 SUPERFAMILY SSF54862 235 301 7.53E-9 T 29-03-2018 CWR56_RS09325 422168a7791f7b683945ee5b07297b97 345 Pfam PF13486 Reductive dehalogenase subunit 127 230 1.9E-9 T 29-03-2018 IPR028894 Reductive dehalogenase domain CWR56_RS01180 d739a50d814d3382d56ddb21f700db96 70 SUPERFAMILY SSF117130 1 55 4.97E-17 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CWR56_RS01180 d739a50d814d3382d56ddb21f700db96 70 Pfam PF02599 Global regulator protein family 1 52 2.0E-22 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CWR56_RS01180 d739a50d814d3382d56ddb21f700db96 70 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 66 9.3E-23 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CWR56_RS01180 d739a50d814d3382d56ddb21f700db96 70 Hamap MF_00167 Carbon storage regulator [csrA]. 1 67 18.577 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CWR56_RS01180 d739a50d814d3382d56ddb21f700db96 70 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-10 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CWR56_RS13095 58490d80437620735fe6d5a7873701a4 293 Pfam PF03755 YicC-like family, N-terminal region 4 156 1.3E-42 T 29-03-2018 IPR013527 YicC-like, N-terminal CWR56_RS13095 58490d80437620735fe6d5a7873701a4 293 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 293 6.6E-81 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CWR56_RS13095 58490d80437620735fe6d5a7873701a4 293 Gene3D G3DSA:3.40.1350.10 13 129 0.0013 T 29-03-2018 CWR56_RS13095 58490d80437620735fe6d5a7873701a4 293 Pfam PF08340 Domain of unknown function (DUF1732) 209 293 6.0E-36 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 CWR56_RS09140 9bceb068c5ac15fab931b2ed9e38a5e8 157 Gene3D G3DSA:2.60.120.10 15 157 9.2E-33 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS09140 9bceb068c5ac15fab931b2ed9e38a5e8 157 Pfam PF06249 Ethanolamine utilisation protein EutQ 6 155 8.7E-75 T 29-03-2018 IPR010424 Ethanolamine utilisation EutQ CWR56_RS09140 9bceb068c5ac15fab931b2ed9e38a5e8 157 SUPERFAMILY SSF51182 39 153 8.43E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS05970 e38856abf23e8d11a00bb9948e271591 245 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 235 1.9E-23 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 SMART SM00871 114 267 1.3E-21 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 Gene3D G3DSA:1.10.1660.10 1 58 1.5E-17 T 29-03-2018 CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 Gene3D G3DSA:3.20.80.10 124 268 3.5E-26 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 SUPERFAMILY SSF55136 115 268 1.31E-14 T 29-03-2018 CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 Gene3D G3DSA:1.10.1660.10 59 123 0.0036 T 29-03-2018 CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 Pfam PF06445 GyrI-like small molecule binding domain 116 267 1.1E-11 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 SUPERFAMILY SSF46955 2 93 8.06E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 Pfam PF13411 MerR HTH family regulatory protein 2 70 3.2E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18055 b83b0ea69615b956fb82dcf3c6776302 270 SMART SM00422 2 72 6.7E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS18050 8d98b887214393874ef32b1514ce6d96 205 PIRSF PIRSF024492 1 173 1.3E-49 T 29-03-2018 IPR014519 Uncharacterised conserved protein UCP024492 CWR56_RS18050 8d98b887214393874ef32b1514ce6d96 205 Pfam PF04343 Protein of unknown function, DUF488 14 128 6.8E-20 T 29-03-2018 IPR007438 Protein of unknown function DUF488 CWR56_RS07300 2ccd44d78989db8e5971567feb6783f5 463 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 419 1.1E-62 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07300 2ccd44d78989db8e5971567feb6783f5 463 PIRSF PIRSF006603 1 456 5.7E-95 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07300 2ccd44d78989db8e5971567feb6783f5 463 Pfam PF01554 MatE 250 404 8.4E-25 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07300 2ccd44d78989db8e5971567feb6783f5 463 Pfam PF01554 MatE 22 185 8.1E-30 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS12805 f6a42fdc84ecb185223bff95c0619b48 795 Gene3D G3DSA:1.20.1250.20 256 775 3.6E-7 T 29-03-2018 CWR56_RS12805 f6a42fdc84ecb185223bff95c0619b48 795 Pfam PF02687 FtsX-like permease family 287 364 6.0E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS02880 aabe194a5710fe674999b553078720bd 250 SUPERFAMILY SSF52540 1 222 2.03E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02880 aabe194a5710fe674999b553078720bd 250 SMART SM00382 30 217 5.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS02880 aabe194a5710fe674999b553078720bd 250 Pfam PF00005 ABC transporter 21 169 4.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS02880 aabe194a5710fe674999b553078720bd 250 Gene3D G3DSA:3.40.50.300 1 243 7.1E-60 T 29-03-2018 CWR56_RS01125 b4bb7ef2ab351bd7b2ad9c8cfeba4013 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 3.7E-143 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CWR56_RS01125 b4bb7ef2ab351bd7b2ad9c8cfeba4013 289 SUPERFAMILY SSF53448 1 285 2.05E-85 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01125 b4bb7ef2ab351bd7b2ad9c8cfeba4013 289 Gene3D G3DSA:3.90.550.10 1 289 2.0E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS01125 b4bb7ef2ab351bd7b2ad9c8cfeba4013 289 Pfam PF00483 Nucleotidyl transferase 2 236 5.1E-65 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 Pfam PF00771 FHIPEP family 21 673 4.2E-267 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 28 41 3.8E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 227 241 3.8E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 65 84 3.8E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 146 164 3.8E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 127 143 3.8E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 176 193 3.8E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 11 681 1.8E-260 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CWR56_RS01345 5ca40d13a905ad551af0a8ba631083eb 691 PIRSF PIRSF005419 2 687 3.7E-256 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CWR56_RS05840 d88b667f2a43d027589fa7df16f05ca6 255 SUPERFAMILY SSF53098 64 250 5.31E-67 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS05840 d88b667f2a43d027589fa7df16f05ca6 255 Pfam PF01351 Ribonuclease HII 77 251 9.3E-39 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CWR56_RS05840 d88b667f2a43d027589fa7df16f05ca6 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 74 253 36.643 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 CWR56_RS05840 d88b667f2a43d027589fa7df16f05ca6 255 Gene3D G3DSA:3.30.420.10 50 253 8.4E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS08950 cc6d349d4765c1abbcd1313aea450315 288 Pfam PF00005 ABC transporter 19 161 9.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS08950 cc6d349d4765c1abbcd1313aea450315 288 SMART SM00382 26 208 6.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS08950 cc6d349d4765c1abbcd1313aea450315 288 SUPERFAMILY SSF52540 3 228 8.49E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS08950 cc6d349d4765c1abbcd1313aea450315 288 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS08950 cc6d349d4765c1abbcd1313aea450315 288 Gene3D G3DSA:3.40.50.300 2 242 1.2E-63 T 29-03-2018 CWR56_RS12985 ffc8800aedb6a90bf9f57300a31da441 368 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 11 342 1.1E-64 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS12985 ffc8800aedb6a90bf9f57300a31da441 368 Pfam PF02378 Phosphotransferase system, EIIC 18 293 1.9E-11 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15035 3d42996db12b68270d92fcf198e4a28e 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 149 1.0E-41 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15035 3d42996db12b68270d92fcf198e4a28e 153 SUPERFAMILY SSF55804 2 149 2.09E-41 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15035 3d42996db12b68270d92fcf198e4a28e 153 Gene3D G3DSA:3.40.930.10 1 151 1.7E-43 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR56_RS15035 3d42996db12b68270d92fcf198e4a28e 153 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CWR56_RS15035 3d42996db12b68270d92fcf198e4a28e 153 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 133 1.0E-38 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR56_RS05325 cbf66e5ac3465533e1ab9a28f06a0d9b 265 SUPERFAMILY SSF52402 4 260 1.26E-71 T 29-03-2018 CWR56_RS05325 cbf66e5ac3465533e1ab9a28f06a0d9b 265 SMART SM00893 25 216 9.5E-54 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS05325 cbf66e5ac3465533e1ab9a28f06a0d9b 265 PIRSF PIRSF000090 4 265 7.1E-81 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CWR56_RS05325 cbf66e5ac3465533e1ab9a28f06a0d9b 265 Gene3D G3DSA:3.40.50.620 1 265 2.5E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS05325 cbf66e5ac3465533e1ab9a28f06a0d9b 265 Pfam PF01012 Electron transfer flavoprotein domain 25 210 4.3E-43 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 178 7.4E-39 T 29-03-2018 CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 SUPERFAMILY SSF89447 1 51 6.67E-14 T 29-03-2018 CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 SMART SM00966 8 52 1.4E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 178 3.6E-71 T 29-03-2018 IPR014213 Sporulation stage V, protein T CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.2E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 SUPERFAMILY SSF55781 107 177 1.92E-6 T 29-03-2018 IPR029016 GAF domain-like CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 PIRSF PIRSF026579 1 179 3.3E-72 T 29-03-2018 IPR014213 Sporulation stage V, protein T CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 2.4E-15 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CWR56_RS17450 8d7b75699f0c3fb96aa928e6f0560b96 179 Gene3D G3DSA:2.10.260.10 1 49 1.2E-19 T 29-03-2018 CWR56_RS07925 8a3297bb64c7078ef9f377d1cbc1eb81 41 SUPERFAMILY SSF56349 1 33 2.94E-6 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR56_RS07925 8a3297bb64c7078ef9f377d1cbc1eb81 41 Gene3D G3DSA:1.10.443.10 1 38 6.7E-5 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR56_RS16285 b69976aa65c9982f07ac076ce21a301d 252 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 8 248 7.3E-12 T 29-03-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CWR56_RS16285 b69976aa65c9982f07ac076ce21a301d 252 TIGRFAM TIGR04482 D_pro_red_PrdD: proline reductase cluster protein PrdD 7 252 7.2E-120 T 29-03-2018 IPR031000 Proline reductase cluster protein PrdD CWR56_RS10480 0c15d95fe8831eb8d599184d54939afe 249 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS10480 0c15d95fe8831eb8d599184d54939afe 249 SUPERFAMILY SSF52540 1 238 6.86E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS10480 0c15d95fe8831eb8d599184d54939afe 249 SMART SM00382 26 216 4.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS10480 0c15d95fe8831eb8d599184d54939afe 249 Gene3D G3DSA:3.40.50.300 1 247 9.4E-74 T 29-03-2018 CWR56_RS10480 0c15d95fe8831eb8d599184d54939afe 249 PIRSF PIRSF039085 1 244 2.6E-107 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWR56_RS10480 0c15d95fe8831eb8d599184d54939afe 249 Pfam PF00005 ABC transporter 17 168 1.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS10780 c08bf6474df3f7eb1af374c666eaaa57 266 SUPERFAMILY SSF53474 79 235 7.27E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS10780 c08bf6474df3f7eb1af374c666eaaa57 266 Pfam PF12695 Alpha/beta hydrolase family 89 251 3.1E-74 T 29-03-2018 IPR029059 Alpha/beta hydrolase fold-5 CWR56_RS10780 c08bf6474df3f7eb1af374c666eaaa57 266 Gene3D G3DSA:3.40.50.1820 85 264 2.5E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS04795 ed62d63d64b097a8bb182f5d41edf188 350 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 17 350 2.3E-71 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI CWR56_RS04795 ed62d63d64b097a8bb182f5d41edf188 350 Pfam PF01594 AI-2E family transporter 19 334 3.0E-45 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 Pfam PF00162 Phosphoglycerate kinase 9 389 1.2E-165 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 SUPERFAMILY SSF53748 4 399 1.88E-156 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 Gene3D G3DSA:3.40.50.1260 6 184 1.2E-74 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 Gene3D G3DSA:3.40.50.1260 185 387 9.5E-88 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PIRSF PIRSF000724 1 400 5.0E-155 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 114 129 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 375 392 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 173 195 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 196 215 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 318 343 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 PRINTS PR00477 Phosphoglycerate kinase family signature 352 363 7.0E-92 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS15930 5494e7480fce267c228d7335758dfec7 400 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 399 42.425 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR56_RS06875 2b615f2d8e2452e6b2f02d2eab58f8f1 363 SUPERFAMILY SSF81665 224 268 1.7E-5 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS06875 2b615f2d8e2452e6b2f02d2eab58f8f1 363 SUPERFAMILY SSF81665 32 119 1.7E-5 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS06875 2b615f2d8e2452e6b2f02d2eab58f8f1 363 Pfam PF07853 Protein of unknown function (DUF1648) 153 190 9.0E-11 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CWR56_RS10250 058a56a94b9c29ba5de25ea2f1eef4b4 334 Pfam PF02163 Peptidase family M50 6 319 1.6E-68 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CWR56_RS10250 058a56a94b9c29ba5de25ea2f1eef4b4 334 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 117 333 2.7E-47 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CWR56_RS10250 058a56a94b9c29ba5de25ea2f1eef4b4 334 Gene3D G3DSA:2.30.42.10 117 198 5.6E-19 T 29-03-2018 CWR56_RS10250 058a56a94b9c29ba5de25ea2f1eef4b4 334 Pfam PF13180 PDZ domain 121 181 3.7E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS10250 058a56a94b9c29ba5de25ea2f1eef4b4 334 SMART SM00228 106 173 1.6E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS10250 058a56a94b9c29ba5de25ea2f1eef4b4 334 SUPERFAMILY SSF50156 77 183 3.29E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CWR56_RS07020 1402ab4c45274ce77251fb24552c29ab 218 Gene3D G3DSA:1.10.3720.10 6 218 2.4E-36 T 29-03-2018 CWR56_RS07020 1402ab4c45274ce77251fb24552c29ab 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 205 7.3E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS07020 1402ab4c45274ce77251fb24552c29ab 218 SUPERFAMILY SSF161098 12 205 6.8E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS02070 7d180f6eed9d9f66923803cffb86de49 473 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 451 1.4E-133 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CWR56_RS02070 7d180f6eed9d9f66923803cffb86de49 473 Pfam PF03553 Na+/H+ antiporter family 162 454 4.4E-55 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 Gene3D G3DSA:1.10.4030.10 20 149 1.1E-12 T 29-03-2018 CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 SUPERFAMILY SSF109998 21 200 6.67E-23 T 29-03-2018 IPR027304 Trigger factor/SurA domain CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 Pfam PF13624 SurA N-terminal domain 18 144 3.8E-10 T 29-03-2018 CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 SUPERFAMILY SSF54534 174 282 2.09E-27 T 29-03-2018 CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 218 239 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 Pfam PF13616 PPIC-type PPIASE domain 165 281 1.9E-35 T 29-03-2018 CWR56_RS07385 967c791b152eec95d4e385c59ed7b308 318 Gene3D G3DSA:3.10.50.40 165 304 8.9E-36 T 29-03-2018 CWR56_RS12905 689ad22e7e5bbbc89d5228e734c16842 419 Pfam PF03611 PTS system sugar-specific permease component 8 383 1.4E-87 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWR56_RS16065 03fbb48f152da97fe795e2562a2fb8f1 337 Pfam PF12698 ABC-2 family transporter protein 17 325 5.9E-33 T 29-03-2018 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 Gene3D G3DSA:3.40.630.10 231 387 9.0E-21 T 29-03-2018 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 Gene3D G3DSA:3.40.630.10 1 223 1.1E-46 T 29-03-2018 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 373 3.2E-116 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 SUPERFAMILY SSF53187 2 195 8.38E-84 T 29-03-2018 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 SUPERFAMILY SSF53187 296 386 8.38E-84 T 29-03-2018 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 SUPERFAMILY SSF55031 182 289 2.49E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 Pfam PF07687 Peptidase dimerisation domain 184 281 6.6E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 Pfam PF01546 Peptidase family M20/M25/M40 71 381 4.5E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS05025 cbb3d35ccbd13901f28d39e6772bb912 387 PIRSF PIRSF005962 1 387 5.8E-131 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS04560 adb0769a2aea2d77c72084e8dd5d8c04 279 Pfam PF05681 Fumarate hydratase (Fumerase) 11 277 9.4E-116 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CWR56_RS04560 adb0769a2aea2d77c72084e8dd5d8c04 279 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 9 278 6.3E-102 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CWR56_RS15750 21bd8557144f42c2d91ab109d2df3f6d 127 Pfam PF08870 DNA sulphur modification protein DndE 4 110 5.6E-28 T 29-03-2018 IPR014969 DNA sulphur modification protein DndE CWR56_RS10375 aed03ed6aa2c0d066633a0ff1b4f09e4 83 SUPERFAMILY SSF55021 1 79 2.29E-23 T 29-03-2018 CWR56_RS10375 aed03ed6aa2c0d066633a0ff1b4f09e4 83 Gene3D G3DSA:3.30.70.1150 3 77 3.1E-17 T 29-03-2018 CWR56_RS10375 aed03ed6aa2c0d066633a0ff1b4f09e4 83 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 3 78 6.1E-28 T 29-03-2018 IPR023860 [FeFe]-hydrogenase system regulator TM1266 CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 SUPERFAMILY SSF52540 4 253 1.54E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 Gene3D G3DSA:3.40.50.300 1 330 2.7E-80 T 29-03-2018 CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 Pfam PF00005 ABC transporter 25 182 3.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 1.2E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 290 2.2E-12 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR56_RS04210 026451d7a1bd5fa2031d0c2d0a11a9ca 341 SMART SM00382 33 240 2.1E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 SUPERFAMILY SSF74650 383 869 3.45E-73 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 Pfam PF09261 Alpha mannosidase middle domain 277 353 2.6E-9 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 Gene3D G3DSA:3.20.110.10 1 263 5.8E-60 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 Gene3D G3DSA:1.20.1270.50 276 368 3.6E-17 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 SUPERFAMILY SSF88688 277 373 1.83E-8 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 384 868 2.0E-34 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 Gene3D G3DSA:2.60.40.1180 369 500 1.6E-14 T 29-03-2018 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 4 263 3.8E-42 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 SMART SM00872 276 354 3.8E-18 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWR56_RS15410 febb5e2c565b1e49a8549a9f2d572559 871 SUPERFAMILY SSF88713 2 256 4.61E-52 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS06730 e3de879f793297c3f22d6ed36bb00150 199 Pfam PF00075 RNase H 65 197 1.2E-11 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CWR56_RS06730 e3de879f793297c3f22d6ed36bb00150 199 Pfam PF01693 Caulimovirus viroplasmin 5 48 1.0E-20 T 29-03-2018 IPR011320 Ribonuclease H1, N-terminal CWR56_RS06730 e3de879f793297c3f22d6ed36bb00150 199 SUPERFAMILY SSF53098 63 198 2.66E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS06730 e3de879f793297c3f22d6ed36bb00150 199 Gene3D G3DSA:3.40.970.10 2 53 2.0E-23 T 29-03-2018 IPR011320 Ribonuclease H1, N-terminal CWR56_RS06730 e3de879f793297c3f22d6ed36bb00150 199 SUPERFAMILY SSF55658 5 49 5.75E-16 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CWR56_RS06730 e3de879f793297c3f22d6ed36bb00150 199 Gene3D G3DSA:3.30.420.10 54 196 9.1E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 SMART SM00862 153 229 1.4E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 SUPERFAMILY SSF52172 2 182 3.02E-39 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 SMART SM00448 2 114 8.1E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 9.5E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 Pfam PF00072 Response regulator receiver domain 4 115 6.8E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 Gene3D G3DSA:1.10.10.10 150 233 2.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01675 48717ab9e232fa9ce54d91c682e13fb6 233 Gene3D G3DSA:3.40.50.2300 2 149 3.1E-39 T 29-03-2018 CWR56_RS13500 86b7661d2f12f1508ec8864d99b582ff 680 Pfam PF00999 Sodium/hydrogen exchanger family 10 431 7.0E-50 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR56_RS00805 c679836759949b835c6d06e06088d2e1 449 Pfam PF13520 Amino acid permease 7 390 2.1E-55 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS00805 c679836759949b835c6d06e06088d2e1 449 PIRSF PIRSF006060 1 448 5.6E-78 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS13420 dc5c32df4a35757241edde8e2712d13d 376 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 21 371 4.3E-136 T 29-03-2018 IPR013438 Sporulation stage V, protein E CWR56_RS13420 dc5c32df4a35757241edde8e2712d13d 376 Pfam PF01098 Cell cycle protein 22 374 6.3E-112 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWR56_RS13420 dc5c32df4a35757241edde8e2712d13d 376 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 21 372 3.0E-120 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CWR56_RS00795 bc05609afdf8db907f017097c0dd35f2 777 Pfam PF02687 FtsX-like permease family 680 768 1.9E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS00795 bc05609afdf8db907f017097c0dd35f2 777 Pfam PF02687 FtsX-like permease family 277 374 2.5E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS00795 bc05609afdf8db907f017097c0dd35f2 777 Pfam PF12704 MacB-like periplasmic core domain 22 214 1.1E-8 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CWR56_RS00795 bc05609afdf8db907f017097c0dd35f2 777 Gene3D G3DSA:1.20.1250.20 9 769 2.1E-7 T 29-03-2018 CWR56_RS04510 1518bf1876b84b78d219b6bde149789b 358 PIRSF PIRSF000524 1 355 2.1E-90 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CWR56_RS04510 1518bf1876b84b78d219b6bde149789b 358 SUPERFAMILY SSF53383 5 355 2.8E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS04510 1518bf1876b84b78d219b6bde149789b 358 Gene3D G3DSA:3.40.640.10 11 260 4.7E-27 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS04510 1518bf1876b84b78d219b6bde149789b 358 Pfam PF00266 Aminotransferase class-V 25 346 2.0E-29 T 29-03-2018 IPR000192 Aminotransferase class V domain CWR56_RS04510 1518bf1876b84b78d219b6bde149789b 358 Gene3D G3DSA:3.90.1150.10 261 355 6.4E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS12775 f55dee864f6f94aa6da4edccb7a0f4df 213 SUPERFAMILY SSF48498 83 177 2.08E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR56_RS12775 f55dee864f6f94aa6da4edccb7a0f4df 213 SUPERFAMILY SSF46689 4 67 1.23E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS12775 f55dee864f6f94aa6da4edccb7a0f4df 213 Gene3D G3DSA:1.10.10.60 48 182 2.1E-7 T 29-03-2018 CWR56_RS12775 f55dee864f6f94aa6da4edccb7a0f4df 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 61 5.7E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS12775 f55dee864f6f94aa6da4edccb7a0f4df 213 Gene3D G3DSA:1.10.10.60 2 47 4.1E-15 T 29-03-2018 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 PIRSF PIRSF000728 8 283 1.8E-111 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 TIGRFAM TIGR00761 argB: acetylglutamate kinase 24 258 5.7E-81 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 SUPERFAMILY SSF53633 4 284 8.9E-92 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 Pfam PF00696 Amino acid kinase family 23 259 3.8E-48 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 Gene3D G3DSA:3.40.1160.10 1 286 7.6E-74 T 29-03-2018 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 PRINTS PR00474 Glutamate 5-kinase family signature 180 207 5.9E-13 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 PRINTS PR00474 Glutamate 5-kinase family signature 54 68 5.9E-13 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 PRINTS PR00474 Glutamate 5-kinase family signature 233 253 5.9E-13 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWR56_RS09710 ceb23c350bf1438d458ed69b510b6dbd 286 Hamap MF_00082_B Acetylglutamate kinase [argB]. 21 283 35.875 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR56_RS12240 52d60d760f80024bc3e5b50d37c3a712 297 PIRSF PIRSF000428 1 297 2.2E-81 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS12240 52d60d760f80024bc3e5b50d37c3a712 297 SUPERFAMILY SSF53659 5 295 1.77E-65 T 29-03-2018 CWR56_RS12240 52d60d760f80024bc3e5b50d37c3a712 297 Pfam PF01515 Phosphate acetyl/butaryl transferase 77 293 2.5E-43 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS12240 52d60d760f80024bc3e5b50d37c3a712 297 Pfam PF01515 Phosphate acetyl/butaryl transferase 7 73 5.8E-6 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR56_RS12240 52d60d760f80024bc3e5b50d37c3a712 297 Gene3D G3DSA:3.40.50.10750 114 269 3.8E-38 T 29-03-2018 CWR56_RS06630 534a310c109e20bfca73d8a2e5a5dcbb 142 Pfam PF04657 Putative inner membrane exporter, YdcZ 6 138 1.9E-24 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CWR56_RS05945 51574ffb401e295f5ebb946ed6dd5b69 85 Pfam PF06135 Bacterial protein of unknown function (DUF965) 6 83 4.9E-33 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWR56_RS05945 51574ffb401e295f5ebb946ed6dd5b69 85 Hamap MF_01507 UPF0297 protein . 2 85 24.82 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWR56_RS11155 ced913bb9a4151c6db0c84006c4d7b38 1015 Pfam PF00746 LPXTG cell wall anchor motif 979 1014 9.6E-4 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWR56_RS11155 ced913bb9a4151c6db0c84006c4d7b38 1015 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 979 1011 1.1E-4 T 29-03-2018 CWR56_RS11155 ced913bb9a4151c6db0c84006c4d7b38 1015 Gene3D G3DSA:2.60.40.10 203 304 7.9E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS11155 ced913bb9a4151c6db0c84006c4d7b38 1015 Gene3D G3DSA:2.60.40.810 440 565 7.3E-15 T 29-03-2018 CWR56_RS11155 ced913bb9a4151c6db0c84006c4d7b38 1015 Gene3D G3DSA:2.60.40.810 305 433 6.9E-7 T 29-03-2018 CWR56_RS11155 ced913bb9a4151c6db0c84006c4d7b38 1015 Gene3D G3DSA:2.60.40.810 566 726 1.9E-12 T 29-03-2018 CWR56_RS05830 4c652fa151f1da5bb3be4512cfb9a34b 430 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 411 2.3E-104 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR56_RS05830 4c652fa151f1da5bb3be4512cfb9a34b 430 Pfam PF05525 Branched-chain amino acid transport protein 9 424 1.5E-119 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR56_RS17605 4719b1d88c61f2eb02aa1186b2399458 278 SUPERFAMILY SSF89550 167 252 2.22E-45 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS17605 4719b1d88c61f2eb02aa1186b2399458 278 SUPERFAMILY SSF89550 2 83 2.22E-45 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS17605 4719b1d88c61f2eb02aa1186b2399458 278 Gene3D G3DSA:3.20.20.140 2 257 1.6E-42 T 29-03-2018 CWR56_RS17605 4719b1d88c61f2eb02aa1186b2399458 278 SMART SM00481 3 68 1.3E-11 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS17605 4719b1d88c61f2eb02aa1186b2399458 278 Pfam PF02811 PHP domain 4 160 9.8E-10 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS14315 6ad39d70375338f29187b4e4aa6d8337 169 Pfam PF07670 Nucleoside recognition 37 125 2.8E-10 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS08970 4ed51f0c2801a3527ed5f5a98d89cbc3 163 Pfam PF04073 Aminoacyl-tRNA editing domain 24 150 1.1E-29 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS08970 4ed51f0c2801a3527ed5f5a98d89cbc3 163 Gene3D G3DSA:3.90.960.10 1 163 1.0E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS08970 4ed51f0c2801a3527ed5f5a98d89cbc3 163 SUPERFAMILY SSF55826 5 161 6.41E-42 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR56_RS02830 a04297eb9d46f46ede4feda69e0e4791 178 SUPERFAMILY SSF81301 11 174 1.73E-41 T 29-03-2018 CWR56_RS02830 a04297eb9d46f46ede4feda69e0e4791 178 Gene3D G3DSA:3.30.460.10 5 177 2.2E-42 T 29-03-2018 CWR56_RS02830 a04297eb9d46f46ede4feda69e0e4791 178 Pfam PF04229 GrpB protein 9 168 3.4E-39 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CWR56_RS08230 86d6a1c729364f08468e5d0597d11c42 514 SUPERFAMILY SSF53067 267 442 2.69E-22 T 29-03-2018 CWR56_RS08230 86d6a1c729364f08468e5d0597d11c42 514 SUPERFAMILY SSF53067 1 80 4.15E-9 T 29-03-2018 CWR56_RS08230 86d6a1c729364f08468e5d0597d11c42 514 Pfam PF01968 Hydantoinase/oxoprolinase 192 361 1.8E-23 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CWR56_RS08230 86d6a1c729364f08468e5d0597d11c42 514 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 172 1.8E-35 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CWR56_RS08230 86d6a1c729364f08468e5d0597d11c42 514 Gene3D G3DSA:3.30.420.40 264 427 2.3E-9 T 29-03-2018 CWR56_RS08230 86d6a1c729364f08468e5d0597d11c42 514 Gene3D G3DSA:3.30.420.40 1 237 2.4E-11 T 29-03-2018 CWR56_RS04985 2f4cbcdab21e1586b5e90acbf3f14d98 280 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 16 279 6.1E-97 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWR56_RS12510 2ec4f8e8eafe0f98549edc3f467c3cf5 431 Pfam PF03772 Competence protein 154 408 7.6E-51 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CWR56_RS12510 2ec4f8e8eafe0f98549edc3f467c3cf5 431 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 174 337 2.9E-25 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CWR56_RS12510 2ec4f8e8eafe0f98549edc3f467c3cf5 431 SUPERFAMILY SSF81665 3 40 3.53E-5 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS12510 2ec4f8e8eafe0f98549edc3f467c3cf5 431 SUPERFAMILY SSF81665 165 408 3.53E-5 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 Gene3D G3DSA:3.40.50.2300 1 149 1.2E-46 T 29-03-2018 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 3.5E-13 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 80 95 3.5E-13 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 3.5E-13 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 102 115 3.5E-13 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 120 135 3.5E-13 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 SMART SM00226 1 148 3.3E-39 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 144 1.3E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR56_RS17355 1f2ac9479a7ab3d3a7d56f77edaa2489 149 SUPERFAMILY SSF52788 1 149 2.09E-40 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR56_RS13640 020d45edad8c953b47d8e461e69a8ce6 333 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 16 326 7.9E-102 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWR56_RS13640 020d45edad8c953b47d8e461e69a8ce6 333 SUPERFAMILY SSF55681 16 326 1.89E-91 T 29-03-2018 CWR56_RS13640 020d45edad8c953b47d8e461e69a8ce6 333 Gene3D G3DSA:3.30.930.10 7 328 1.3E-40 T 29-03-2018 CWR56_RS13640 020d45edad8c953b47d8e461e69a8ce6 333 Pfam PF03590 Aspartate-ammonia ligase 19 243 1.7E-105 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWR56_RS13640 020d45edad8c953b47d8e461e69a8ce6 333 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 11 329 47.931 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWR56_RS13640 020d45edad8c953b47d8e461e69a8ce6 333 PIRSF PIRSF001555 7 333 1.9E-153 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWR56_RS12850 63d10b7c0d01e14859b1e412edc7bb9f 402 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 116 218 7.4E-12 T 29-03-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain CWR56_RS12850 63d10b7c0d01e14859b1e412edc7bb9f 402 Gene3D G3DSA:3.40.50.1110 17 231 2.6E-5 T 29-03-2018 CWR56_RS13195 e19a905587d3c9eb5006cb833a3f5079 232 Pfam PF01048 Phosphorylase superfamily 4 229 9.6E-51 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR56_RS13195 e19a905587d3c9eb5006cb833a3f5079 232 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 4 232 8.1E-62 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR56_RS13195 e19a905587d3c9eb5006cb833a3f5079 232 Gene3D G3DSA:3.40.50.1580 2 232 2.2E-51 T 29-03-2018 CWR56_RS13195 e19a905587d3c9eb5006cb833a3f5079 232 SUPERFAMILY SSF53167 4 230 2.75E-61 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR56_RS02630 289113c64ea5019a1c29e0a02a528628 370 Gene3D G3DSA:3.40.50.2300 196 370 3.5E-35 T 29-03-2018 CWR56_RS02630 289113c64ea5019a1c29e0a02a528628 370 SUPERFAMILY SSF53822 80 321 1.6E-14 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS02630 289113c64ea5019a1c29e0a02a528628 370 Gene3D G3DSA:3.40.50.2300 78 195 9.4E-28 T 29-03-2018 CWR56_RS02630 289113c64ea5019a1c29e0a02a528628 370 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 83 365 4.4E-59 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CWR56_RS16350 a1732cfcddb8c46e30b80d25f97c9fa8 81 TIGRFAM TIGR03905 TIGR03905_4_Cys: uncharacterized protein TIGR03905 4 79 2.2E-26 T 29-03-2018 IPR023806 Conserved hypothetical protein CHP03905 CWR56_RS16350 a1732cfcddb8c46e30b80d25f97c9fa8 81 Pfam PF12637 TSCPD domain 5 79 3.8E-28 T 29-03-2018 IPR024434 TSCPD domain CWR56_RS13615 b4276538c58715482fdd0dc61a655218 310 SUPERFAMILY SSF48317 5 167 2.49E-31 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS13615 b4276538c58715482fdd0dc61a655218 310 Gene3D G3DSA:1.20.144.10 24 172 6.7E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS13615 b4276538c58715482fdd0dc61a655218 310 Pfam PF01569 PAP2 superfamily 54 165 4.2E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS13615 b4276538c58715482fdd0dc61a655218 310 SMART SM00014 49 161 9.1E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR56_RS14260 041abdaa2e9bba939d990b0a0bfcb391 284 Gene3D G3DSA:3.40.50.300 88 283 7.8E-5 T 29-03-2018 CWR56_RS14260 041abdaa2e9bba939d990b0a0bfcb391 284 Pfam PF06541 Putative ABC-transporter type IV 9 163 1.7E-51 T 29-03-2018 IPR010540 Putative ABC-transporter type IV CmpB/TMEM229 CWR56_RS00735 c9b3a8dd3d14c41e8db6130ab85f76f4 902 Pfam PF02901 Pyruvate formate lyase-like 39 763 1.3E-154 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CWR56_RS00735 c9b3a8dd3d14c41e8db6130ab85f76f4 902 Gene3D G3DSA:3.20.70.20 36 901 3.2E-217 T 29-03-2018 CWR56_RS00735 c9b3a8dd3d14c41e8db6130ab85f76f4 902 Pfam PF01228 Glycine radical 784 882 1.9E-20 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CWR56_RS00735 c9b3a8dd3d14c41e8db6130ab85f76f4 902 SUPERFAMILY SSF51998 31 900 2.62E-173 T 29-03-2018 CWR56_RS07380 cfe6648939231db97dc15d8d1aa951f7 277 Gene3D G3DSA:3.20.20.370 40 263 5.1E-44 T 29-03-2018 CWR56_RS07380 cfe6648939231db97dc15d8d1aa951f7 277 SUPERFAMILY SSF88713 72 264 1.46E-45 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS07380 cfe6648939231db97dc15d8d1aa951f7 277 Pfam PF01522 Polysaccharide deacetylase 72 194 2.5E-28 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS07375 01323f47fa3fefc289560309bfdad06f 442 PIRSF PIRSF006060 1 440 5.4E-79 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS07375 01323f47fa3fefc289560309bfdad06f 442 Pfam PF13520 Amino acid permease 11 411 1.7E-61 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 3.8E-100 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 Gene3D G3DSA:3.90.230.10 1 248 7.5E-77 T 29-03-2018 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 41.517 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 SUPERFAMILY SSF55920 1 247 1.16E-85 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS00195 736de23c67ce493f4b6b2fb5e2e5fad8 248 Pfam PF00557 Metallopeptidase family M24 11 239 3.1E-51 T 29-03-2018 IPR000994 Peptidase M24 CWR56_RS10010 f4a0546998b476ba48a8311fbcab7810 223 Pfam PF03358 NADPH-dependent FMN reductase 3 149 3.7E-28 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR56_RS10010 f4a0546998b476ba48a8311fbcab7810 223 Gene3D G3DSA:3.40.50.360 1 192 1.6E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS10010 f4a0546998b476ba48a8311fbcab7810 223 SUPERFAMILY SSF52218 1 194 2.02E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS10300 2e4ff7386692c5c3ae8dfc835d671840 234 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 234 1.4E-94 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CWR56_RS10300 2e4ff7386692c5c3ae8dfc835d671840 234 Pfam PF00696 Amino acid kinase family 7 213 4.8E-26 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS10300 2e4ff7386692c5c3ae8dfc835d671840 234 SUPERFAMILY SSF53633 4 233 8.51E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR56_RS10300 2e4ff7386692c5c3ae8dfc835d671840 234 Gene3D G3DSA:3.40.1160.10 1 234 2.0E-40 T 29-03-2018 CWR56_RS10300 2e4ff7386692c5c3ae8dfc835d671840 234 PIRSF PIRSF005650 1 234 4.5E-94 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CWR56_RS10300 2e4ff7386692c5c3ae8dfc835d671840 234 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 234 43.383 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CWR56_RS03095 db0c21cc87fbd080d484f9441a00d6ad 285 Pfam PF00005 ABC transporter 19 158 1.3E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS03095 db0c21cc87fbd080d484f9441a00d6ad 285 Gene3D G3DSA:3.40.50.300 1 241 6.3E-49 T 29-03-2018 CWR56_RS03095 db0c21cc87fbd080d484f9441a00d6ad 285 SMART SM00382 28 214 9.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS03095 db0c21cc87fbd080d484f9441a00d6ad 285 SUPERFAMILY SSF52540 3 221 5.13E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03095 db0c21cc87fbd080d484f9441a00d6ad 285 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS05490 b0186d187c470c187e9d8ec9f7dfd395 401 Pfam PF13742 OB-fold nucleic acid binding domain 7 100 5.1E-24 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CWR56_RS05490 b0186d187c470c187e9d8ec9f7dfd395 401 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 394 26.207 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05490 b0186d187c470c187e9d8ec9f7dfd395 401 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 393 1.1E-140 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CWR56_RS05490 b0186d187c470c187e9d8ec9f7dfd395 401 Pfam PF02601 Exonuclease VII, large subunit 330 391 1.5E-9 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CWR56_RS05490 b0186d187c470c187e9d8ec9f7dfd395 401 Pfam PF02601 Exonuclease VII, large subunit 123 339 2.6E-76 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CWR56_RS05490 b0186d187c470c187e9d8ec9f7dfd395 401 Gene3D G3DSA:2.40.50.140 1 113 1.2E-7 T 29-03-2018 CWR56_RS05760 05f810cf89994fc83ddac4f0a848a4d6 151 Gene3D G3DSA:1.20.58.90 2 97 2.1E-4 T 29-03-2018 CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 ProSitePatterns PS00211 ABC transporters family signature. 700 714 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 SUPERFAMILY SSF52540 269 419 6.83E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 SUPERFAMILY SSF52540 1 52 6.83E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 Gene3D G3DSA:3.40.50.300 1 459 7.0E-45 T 29-03-2018 CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 Gene3D G3DSA:3.40.50.300 461 806 2.6E-49 T 29-03-2018 CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 Pfam PF00005 ABC transporter 476 504 6.5E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 SUPERFAMILY SSF52540 467 514 2.26E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16045 8dbabadfcd90ae76c7c795f46db5f800 806 SUPERFAMILY SSF52540 555 779 2.26E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07635 3df88b46c08057260f25eddd527b974e 238 SMART SM00382 34 209 3.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07635 3df88b46c08057260f25eddd527b974e 238 SUPERFAMILY SSF52540 2 224 8.45E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07635 3df88b46c08057260f25eddd527b974e 238 Pfam PF00005 ABC transporter 25 160 2.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07635 3df88b46c08057260f25eddd527b974e 238 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS07635 3df88b46c08057260f25eddd527b974e 238 Gene3D G3DSA:3.40.50.300 1 238 8.0E-51 T 29-03-2018 CWR56_RS07430 322e20070f9e7059ced7b25f41e10b0c 225 Gene3D G3DSA:1.20.1260.10 1 185 7.1E-65 T 29-03-2018 IPR012347 Ferritin-related CWR56_RS07430 322e20070f9e7059ced7b25f41e10b0c 225 SUPERFAMILY SSF47240 1 211 1.03E-75 T 29-03-2018 IPR009078 Ferritin-like superfamily CWR56_RS07430 322e20070f9e7059ced7b25f41e10b0c 225 Pfam PF05067 Manganese containing catalase 1 184 1.3E-57 T 29-03-2018 IPR007760 Manganese catalase CWR56_RS15080 fd1dec1ffd12cfa39ddebcfcb373f2d7 224 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS15080 fd1dec1ffd12cfa39ddebcfcb373f2d7 224 Pfam PF12838 4Fe-4S dicluster domain 168 217 4.7E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS15080 fd1dec1ffd12cfa39ddebcfcb373f2d7 224 Gene3D G3DSA:3.30.70.20 79 175 3.2E-6 T 29-03-2018 CWR56_RS15080 fd1dec1ffd12cfa39ddebcfcb373f2d7 224 Gene3D G3DSA:3.30.70.20 176 224 4.0E-8 T 29-03-2018 CWR56_RS15080 fd1dec1ffd12cfa39ddebcfcb373f2d7 224 SUPERFAMILY SSF54862 161 222 1.61E-8 T 29-03-2018 CWR56_RS10645 21499a025fa39f2bf6ba153645f61182 260 Pfam PF00756 Putative esterase 39 256 2.8E-22 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CWR56_RS10645 21499a025fa39f2bf6ba153645f61182 260 SUPERFAMILY SSF53474 5 257 6.51E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS10645 21499a025fa39f2bf6ba153645f61182 260 Gene3D G3DSA:3.40.50.1820 1 259 1.6E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS15530 8dcfd2a3e6115790c42b06b3383b9f95 238 Gene3D G3DSA:3.20.20.70 1 229 2.1E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS15530 8dcfd2a3e6115790c42b06b3383b9f95 238 SUPERFAMILY SSF51366 1 223 4.84E-37 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR56_RS15530 8dcfd2a3e6115790c42b06b3383b9f95 238 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 211 7.8E-25 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR56_RS04450 26649bc1c0ecb0cbbd63a72f8f77e2b9 295 Pfam PF01040 UbiA prenyltransferase family 49 271 4.2E-27 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CWR56_RS12205 23e33bac9ae8739aaa3e7e94077798ea 181 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 8 174 4.2E-77 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CWR56_RS12205 23e33bac9ae8739aaa3e7e94077798ea 181 PIRSF PIRSF038321 5 181 2.8E-83 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CWR56_RS12205 23e33bac9ae8739aaa3e7e94077798ea 181 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 6 174 1.4E-56 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CWR56_RS04940 6d8bee16c1e5d5a375d140d01b66a678 264 SUPERFAMILY SSF89550 1 264 1.44E-50 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS04940 6d8bee16c1e5d5a375d140d01b66a678 264 Pfam PF02811 PHP domain 4 193 3.6E-16 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS04940 6d8bee16c1e5d5a375d140d01b66a678 264 Gene3D G3DSA:3.20.20.140 1 261 1.5E-45 T 29-03-2018 CWR56_RS04940 6d8bee16c1e5d5a375d140d01b66a678 264 SMART SM00481 3 84 1.6E-9 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS04940 6d8bee16c1e5d5a375d140d01b66a678 264 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 238 5.6E-54 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CWR56_RS05960 566fe7ed59a12dfa719d2eab41063778 95 Hamap MF_01448 UPF0473 protein . 2 81 15.506 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CWR56_RS05960 566fe7ed59a12dfa719d2eab41063778 95 Pfam PF06949 Protein of unknown function (DUF1292) 11 80 1.3E-13 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CWR56_RS17405 cebf0bbf869314a2ae285bd906c36cca 790 Gene3D G3DSA:3.60.40.10 565 789 4.0E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS17405 cebf0bbf869314a2ae285bd906c36cca 790 SMART SM00332 568 785 0.0056 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS17405 cebf0bbf869314a2ae285bd906c36cca 790 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 31 787 1.2E-188 T 29-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS17405 cebf0bbf869314a2ae285bd906c36cca 790 SUPERFAMILY SSF81606 587 786 6.54E-18 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS17405 cebf0bbf869314a2ae285bd906c36cca 790 SMART SM00331 574 787 1.2E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS17405 cebf0bbf869314a2ae285bd906c36cca 790 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 600 786 1.6E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR56_RS17060 27202699e4a7596a30ff0c24dad92bea 241 Gene3D G3DSA:3.40.1010.10 1 119 2.5E-35 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17060 27202699e4a7596a30ff0c24dad92bea 241 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 2 240 1.6E-105 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CWR56_RS17060 27202699e4a7596a30ff0c24dad92bea 241 SUPERFAMILY SSF53790 1 239 3.66E-57 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17060 27202699e4a7596a30ff0c24dad92bea 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 207 3.4E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17060 27202699e4a7596a30ff0c24dad92bea 241 Gene3D G3DSA:3.30.950.10 120 238 2.6E-52 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS06465 c8eb446f1afdbcbca337c4ffb107d555 263 SUPERFAMILY SSF88713 2 253 2.67E-102 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS06465 c8eb446f1afdbcbca337c4ffb107d555 263 Pfam PF03746 LamB/YcsF family 4 241 8.9E-104 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CWR56_RS06465 c8eb446f1afdbcbca337c4ffb107d555 263 Gene3D G3DSA:3.20.20.370 3 250 2.8E-106 T 29-03-2018 CWR56_RS06465 c8eb446f1afdbcbca337c4ffb107d555 263 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 46.345 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 5.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 5.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 5.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 5.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 Pfam PF01047 MarR family 34 91 1.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 SMART SM00347 27 127 2.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 SUPERFAMILY SSF46785 9 141 1.05E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04190 1494377e7c6689e49588e8659eee94a1 144 Gene3D G3DSA:1.10.10.10 17 126 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 SMART SM00422 126 194 2.3E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 SMART SM00422 4 69 2.0E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 Pfam PF00376 MerR family regulatory protein 5 42 1.7E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 Gene3D G3DSA:1.10.10.10 106 137 0.32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 SUPERFAMILY SSF46955 4 115 8.7E-16 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 Pfam PF13411 MerR HTH family regulatory protein 129 193 4.0E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 Gene3D G3DSA:1.10.1660.10 1 105 1.8E-17 T 29-03-2018 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 Gene3D G3DSA:1.10.1660.10 138 248 3.5E-22 T 29-03-2018 CWR56_RS16055 27ddc453bec4fce520b0e18bba9d8ff0 248 SUPERFAMILY SSF46955 127 201 5.95E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 Gene3D G3DSA:1.10.3860.10 31 454 1.0E-97 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 Pfam PF00375 Sodium:dicarboxylate symporter family 42 446 4.7E-108 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 6.4E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 PRINTS PR00173 Glutamate-aspartate symporter signature 236 255 6.4E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 PRINTS PR00173 Glutamate-aspartate symporter signature 121 146 6.4E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 PRINTS PR00173 Glutamate-aspartate symporter signature 372 391 6.4E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 PRINTS PR00173 Glutamate-aspartate symporter signature 92 112 6.4E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS12845 26b15bcbd5f4cbbfefbf0bd01c9f7eef 462 SUPERFAMILY SSF118215 41 446 6.41E-93 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR56_RS06345 cebebcc87ae1d9f9bd67ce7b59659a31 354 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 223 294 1.0E-8 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain CWR56_RS06345 cebebcc87ae1d9f9bd67ce7b59659a31 354 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 83 225 2.8E-17 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CWR56_RS06345 cebebcc87ae1d9f9bd67ce7b59659a31 354 Pfam PF17482 Phage tail sheath C-terminal domain 232 354 3.8E-15 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 Gene3D G3DSA:3.30.70.100 190 284 3.0E-29 T 29-03-2018 CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 SUPERFAMILY SSF82861 40 123 1.31E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 Pfam PF00924 Mechanosensitive ion channel 85 279 9.0E-53 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 154 188 - T 29-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 SUPERFAMILY SSF82689 193 289 1.83E-30 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 Gene3D G3DSA:2.30.30.60 140 189 1.3E-16 T 29-03-2018 CWR56_RS07705 7c69877550677724cb2a6072905db0cb 294 SUPERFAMILY SSF50182 125 190 2.78E-18 T 29-03-2018 IPR010920 LSM domain CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 SUPERFAMILY SSF144010 7 76 1.03E-48 T 29-03-2018 CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 SUPERFAMILY SSF144010 153 198 1.03E-48 T 29-03-2018 CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 SUPERFAMILY SSF144010 237 329 1.03E-48 T 29-03-2018 CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 SUPERFAMILY SSF144010 360 398 1.03E-48 T 29-03-2018 CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 392 4.1E-87 T 29-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 Gene3D G3DSA:3.30.1330.100 8 127 3.8E-24 T 29-03-2018 CWR56_RS09300 086ab0d73d280ec4734332a786f1172e 399 Gene3D G3DSA:3.30.1330.100 242 399 6.3E-18 T 29-03-2018 CWR56_RS14200 2803b72c335e9038f400d400b099ae20 631 Gene3D G3DSA:3.40.50.2300 307 577 0.01 T 29-03-2018 CWR56_RS14200 2803b72c335e9038f400d400b099ae20 631 Pfam PF04122 Putative cell wall binding repeat 2 429 512 6.4E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14200 2803b72c335e9038f400d400b099ae20 631 Pfam PF04122 Putative cell wall binding repeat 2 323 415 4.2E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14200 2803b72c335e9038f400d400b099ae20 631 Pfam PF04122 Putative cell wall binding repeat 2 526 590 6.8E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14200 2803b72c335e9038f400d400b099ae20 631 Gene3D G3DSA:2.30.42.10 64 181 0.0024 T 29-03-2018 CWR56_RS15240 a9ad34d0e88aec52b6761be8e302b67f 386 Gene3D G3DSA:1.20.1250.20 10 192 3.3E-17 T 29-03-2018 CWR56_RS15240 a9ad34d0e88aec52b6761be8e302b67f 386 Gene3D G3DSA:1.20.1250.20 193 383 2.4E-15 T 29-03-2018 CWR56_RS15240 a9ad34d0e88aec52b6761be8e302b67f 386 Pfam PF12832 MFS_1 like family 14 343 6.6E-23 T 29-03-2018 IPR024989 Major facilitator superfamily associated domain CWR56_RS15240 a9ad34d0e88aec52b6761be8e302b67f 386 SUPERFAMILY SSF103473 12 382 4.58E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS15085 19cfe6e5b900cda1528358d7585a2a16 248 SUPERFAMILY SSF46894 69 118 6.97E-6 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR56_RS15085 19cfe6e5b900cda1528358d7585a2a16 248 Gene3D G3DSA:1.10.10.10 53 154 9.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15085 19cfe6e5b900cda1528358d7585a2a16 248 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 179 246 2.4E-26 T 29-03-2018 IPR018656 Domain of unknown function DUF2087 CWR56_RS01695 ff01d2bd581710143f556c2b770ecf29 250 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 26 241 28.464 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CWR56_RS01695 ff01d2bd581710143f556c2b770ecf29 250 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 27 231 7.6E-52 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 CWR56_RS01695 ff01d2bd581710143f556c2b770ecf29 250 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 26 232 1.6E-90 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CWR56_RS06075 a2f7b1a238d79759ba8cce0e3d0c1779 93 Gene3D G3DSA:3.30.1230.10 2 93 8.3E-33 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CWR56_RS06075 a2f7b1a238d79759ba8cce0e3d0c1779 93 Pfam PF04296 Protein of unknown function (DUF448) 12 84 7.8E-32 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CWR56_RS06075 a2f7b1a238d79759ba8cce0e3d0c1779 93 SUPERFAMILY SSF64376 7 90 1.96E-29 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CWR56_RS10835 537ac655b2bf0ccd7078c0e98e92c23e 500 Pfam PF00474 Sodium:solute symporter family 36 441 6.8E-39 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS10835 537ac655b2bf0ccd7078c0e98e92c23e 500 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 36 442 4.5E-66 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS17620 652a95f5bc6178806e5bec41b698bef6 288 SUPERFAMILY SSF52540 41 286 4.26E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS17620 652a95f5bc6178806e5bec41b698bef6 288 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS17620 652a95f5bc6178806e5bec41b698bef6 288 PIRSF PIRSF037116 31 288 7.8E-84 T 29-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK CWR56_RS17620 652a95f5bc6178806e5bec41b698bef6 288 Gene3D G3DSA:3.40.50.300 40 287 5.4E-59 T 29-03-2018 CWR56_RS17620 652a95f5bc6178806e5bec41b698bef6 288 Pfam PF00005 ABC transporter 56 211 2.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS17620 652a95f5bc6178806e5bec41b698bef6 288 SMART SM00382 64 261 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS11955 dfe4478f2a2cb126415cc744eeaac899 44 Pfam PF12664 Protein of unknown function (DUF3789) 4 35 1.3E-17 T 29-03-2018 IPR024522 Protein of unknown function DUF3789 CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 Pfam PF12838 4Fe-4S dicluster domain 8 52 8.1E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 Gene3D G3DSA:3.30.70.20 27 56 2.5E-7 T 29-03-2018 CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 PRINTS PR00354 7Fe ferredoxin signature 17 27 5.9E-5 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 PRINTS PR00354 7Fe ferredoxin signature 33 50 5.9E-5 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 SUPERFAMILY SSF54862 1 55 4.51E-17 T 29-03-2018 CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS00850 a7f790ff8745486a153ca0dcbba1f3fa 56 Gene3D G3DSA:3.30.70.20 1 26 3.8E-5 T 29-03-2018 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 Pfam PF07687 Peptidase dimerisation domain 187 283 3.6E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 Pfam PF01546 Peptidase family M20/M25/M40 73 385 6.8E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 SUPERFAMILY SSF55031 183 300 8.9E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 377 8.2E-109 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 PIRSF PIRSF005962 1 393 3.3E-118 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 SUPERFAMILY SSF53187 7 199 2.94E-79 T 29-03-2018 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 SUPERFAMILY SSF53187 300 389 2.94E-79 T 29-03-2018 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 Gene3D G3DSA:3.40.630.10 248 395 6.5E-18 T 29-03-2018 CWR56_RS14400 bb07cccfa9f030cb04b52827f8db9f90 396 Gene3D G3DSA:3.40.630.10 3 247 2.1E-38 T 29-03-2018 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 PRINTS PR00721 Stomatin signature 155 173 1.1E-35 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 PRINTS PR00721 Stomatin signature 76 97 1.1E-35 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 PRINTS PR00721 Stomatin signature 111 128 1.1E-35 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 PRINTS PR00721 Stomatin signature 28 50 1.1E-35 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 PRINTS PR00721 Stomatin signature 131 154 1.1E-35 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 PRINTS PR00721 Stomatin signature 174 195 1.1E-35 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 SMART SM00244 21 179 9.3E-60 T 29-03-2018 IPR001107 Band 7 domain CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 Pfam PF01145 SPFH domain / Band 7 family 25 194 6.5E-39 T 29-03-2018 IPR001107 Band 7 domain CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 SUPERFAMILY SSF117892 52 186 6.02E-42 T 29-03-2018 IPR001107 Band 7 domain CWR56_RS04330 c733bdf25aeb2d62e3e6a272bceafe12 347 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 29-03-2018 IPR018080 Band 7/stomatin-like, conserved site CWR56_RS08040 3a2c6f9ff6f6d5ff2445e96f54308ead 322 SUPERFAMILY SSF53590 3 307 1.44E-91 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR56_RS08040 3a2c6f9ff6f6d5ff2445e96f54308ead 322 Gene3D G3DSA:3.90.245.10 1 312 2.3E-92 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR56_RS08040 3a2c6f9ff6f6d5ff2445e96f54308ead 322 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 300 5.8E-83 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR56_RS02365 e0199961b5985cdfcbe5aa3ebee6aba0 253 Pfam PF06738 Putative threonine/serine exporter 10 246 1.3E-70 T 29-03-2018 IPR010619 Putative threonine/serine exporter CWR56_RS11775 cc43de721135f074ff0d6684f40686ed 110 SUPERFAMILY SSF75169 1 110 8.58E-21 T 29-03-2018 IPR027396 DsrEFH-like CWR56_RS11775 cc43de721135f074ff0d6684f40686ed 110 Gene3D G3DSA:3.40.1260.10 2 109 8.5E-11 T 29-03-2018 CWR56_RS11775 cc43de721135f074ff0d6684f40686ed 110 Pfam PF02635 DsrE/DsrF-like family 28 86 1.7E-5 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein CWR56_RS05010 60d655cf3b46fe61c6306738bb420727 91 SUPERFAMILY SSF52794 1 89 4.32E-20 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS05010 60d655cf3b46fe61c6306738bb420727 91 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 61 7.8E-14 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS05010 60d655cf3b46fe61c6306738bb420727 91 Gene3D G3DSA:3.40.50.2300 1 91 2.1E-21 T 29-03-2018 CWR56_RS09795 c17b9c427b525429e95ea7b57be4520f 71 SMART SM00530 6 62 4.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09795 c17b9c427b525429e95ea7b57be4520f 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 5.0E-24 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09795 c17b9c427b525429e95ea7b57be4520f 71 Gene3D G3DSA:1.10.260.40 3 71 1.0E-10 T 29-03-2018 CWR56_RS09795 c17b9c427b525429e95ea7b57be4520f 71 SUPERFAMILY SSF47413 1 69 5.91E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS01195 7b2ca7e90ec6e609f9ce4b66ebe0fa12 507 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 16 114 3.5E-16 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CWR56_RS01195 7b2ca7e90ec6e609f9ce4b66ebe0fa12 507 Gene3D G3DSA:1.10.287.370 24 498 0.0022 T 29-03-2018 CWR56_RS01195 7b2ca7e90ec6e609f9ce4b66ebe0fa12 507 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 248 495 9.6E-32 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 Gene3D G3DSA:1.10.10.10 2 146 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 SUPERFAMILY SSF46785 9 145 1.16E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 6.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 6.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 6.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 6.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 SMART SM00347 26 126 7.1E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04090 0b9703474ef4fff91a1bf8c447dee999 149 Pfam PF01047 MarR family 36 89 2.5E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS04300 33acfbae11c048c2cc74cdc0bb5df4a7 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 265 2.7E-27 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWR56_RS04300 33acfbae11c048c2cc74cdc0bb5df4a7 300 Gene3D G3DSA:1.10.3470.10 1 271 1.3E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS02775 1859518f2694ff24cbe934ab9ffeb3fc 178 SUPERFAMILY SSF110849 8 139 1.2E-24 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS02775 1859518f2694ff24cbe934ab9ffeb3fc 178 SMART SM00470 11 107 3.2E-4 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS02775 1859518f2694ff24cbe934ab9ffeb3fc 178 Pfam PF02195 ParB-like nuclease domain 13 106 1.6E-11 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CWR56_RS02775 1859518f2694ff24cbe934ab9ffeb3fc 178 Gene3D G3DSA:3.90.1530.10 2 111 2.9E-17 T 29-03-2018 CWR56_RS11300 705cc47b4b7aa3eb05425bc007cc4d6f 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 63 5.0E-6 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11300 705cc47b4b7aa3eb05425bc007cc4d6f 100 SUPERFAMILY SSF52794 1 93 1.15E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS11300 705cc47b4b7aa3eb05425bc007cc4d6f 100 Gene3D G3DSA:3.40.50.2300 1 94 1.7E-14 T 29-03-2018 CWR56_RS11130 9aad4f5a344355432f18905eda30ee0a 137 Pfam PF12663 Protein of unknown function (DUF3788) 4 132 1.9E-42 T 29-03-2018 IPR024265 Protein of unknown function DUF3788 CWR56_RS18250 f6e0749a35d3c3099881351024993a4a 159 SUPERFAMILY SSF75217 1 157 3.49E-59 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR56_RS18250 f6e0749a35d3c3099881351024993a4a 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.417 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS18250 f6e0749a35d3c3099881351024993a4a 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 6.7E-59 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS18250 f6e0749a35d3c3099881351024993a4a 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 8.2E-60 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS18250 f6e0749a35d3c3099881351024993a4a 159 PIRSF PIRSF004505 1 159 2.5E-54 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR56_RS18250 f6e0749a35d3c3099881351024993a4a 159 Gene3D G3DSA:3.40.1280.10 1 159 1.8E-62 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR56_RS12420 db8c4f4e766bb1b82ddd0c55552d3831 457 Pfam PF07690 Major Facilitator Superfamily 17 411 6.8E-59 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR56_RS12420 db8c4f4e766bb1b82ddd0c55552d3831 457 SUPERFAMILY SSF103473 250 456 1.66E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS12420 db8c4f4e766bb1b82ddd0c55552d3831 457 SUPERFAMILY SSF103473 5 191 1.66E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS12420 db8c4f4e766bb1b82ddd0c55552d3831 457 Gene3D G3DSA:1.20.1250.20 3 202 4.1E-31 T 29-03-2018 CWR56_RS12420 db8c4f4e766bb1b82ddd0c55552d3831 457 Gene3D G3DSA:1.20.1250.20 257 457 1.4E-26 T 29-03-2018 CWR56_RS01010 afb591f5fe978fa8dc3130f67ec967f8 277 Pfam PF12146 Serine aminopeptidase, S33 29 249 6.0E-11 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CWR56_RS01010 afb591f5fe978fa8dc3130f67ec967f8 277 SUPERFAMILY SSF53474 37 273 2.13E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS01010 afb591f5fe978fa8dc3130f67ec967f8 277 Gene3D G3DSA:3.40.50.1820 13 277 3.1E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS11340 74bb2d3a5785c5a0e5485927309fd549 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 102 3.7E-27 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CWR56_RS11845 305056cc661ec201226cbf6a0663c698 80 Pfam PF12645 Helix-turn-helix domain 9 73 9.9E-25 T 29-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 Pfam PF01311 Bacterial export proteins, family 1 2 232 5.0E-63 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 473 490 1.5E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 453 471 1.5E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 517 532 1.5E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 547 568 1.5E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 255 277 1.5E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 SUPERFAMILY SSF160544 489 596 1.83E-38 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 Pfam PF01312 FlhB HrpN YscU SpaS Family 253 592 9.4E-123 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 Gene3D G3DSA:3.40.1690.10 463 598 1.1E-53 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 253 597 1.7E-121 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CWR56_RS01340 e6161b106be666229050675a6ec52c74 604 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 2 237 1.2E-54 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CWR56_RS06325 1e0d9583d07367110230abe007adb8bb 106 SMART SM00530 5 60 3.6E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS06325 1e0d9583d07367110230abe007adb8bb 106 SUPERFAMILY SSF47413 2 64 6.17E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS06325 1e0d9583d07367110230abe007adb8bb 106 Gene3D G3DSA:1.10.260.40 1 106 1.0E-25 T 29-03-2018 CWR56_RS06325 1e0d9583d07367110230abe007adb8bb 106 Pfam PF01381 Helix-turn-helix 6 60 3.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 Pfam PF01799 [2Fe-2S] binding domain 72 142 2.7E-19 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 SUPERFAMILY SSF47741 73 147 1.31E-22 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 Gene3D G3DSA:3.10.20.30 2 73 1.0E-19 T 29-03-2018 IPR012675 Beta-grasp domain CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 SUPERFAMILY SSF54292 3 76 1.97E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 66 6.2E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CWR56_RS09985 302e8dd59265c021392936eb47b90356 148 Gene3D G3DSA:1.10.150.120 74 148 9.5E-21 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CWR56_RS12665 5d37b7537658284bc4d1b8ab092c0d66 239 Gene3D G3DSA:3.90.260.10 53 143 8.2E-4 T 29-03-2018 IPR002931 Transglutaminase-like CWR56_RS12665 5d37b7537658284bc4d1b8ab092c0d66 239 SUPERFAMILY SSF54001 17 146 2.38E-19 T 29-03-2018 CWR56_RS12665 5d37b7537658284bc4d1b8ab092c0d66 239 Pfam PF01841 Transglutaminase-like superfamily 32 133 1.9E-13 T 29-03-2018 IPR002931 Transglutaminase-like CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 24.801 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 2.8E-28 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 SUPERFAMILY SSF143800 1 65 1.33E-24 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 7.9E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.9E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 7.9E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS17385 b9efb73e7b5c52657b4c12ce79e23c3b 66 Pfam PF01197 Ribosomal protein L31 1 64 3.0E-30 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR56_RS13515 e6dcc0c5796ea2d94bfb3df4a094d168 519 SUPERFAMILY SSF53850 34 515 1.99E-114 T 29-03-2018 CWR56_RS13515 e6dcc0c5796ea2d94bfb3df4a094d168 519 Gene3D G3DSA:3.10.105.10 293 486 1.6E-42 T 29-03-2018 CWR56_RS13515 e6dcc0c5796ea2d94bfb3df4a094d168 519 Gene3D G3DSA:3.90.76.10 52 156 2.0E-24 T 29-03-2018 CWR56_RS13515 e6dcc0c5796ea2d94bfb3df4a094d168 519 PIRSF PIRSF002741 1 518 2.1E-103 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWR56_RS13515 e6dcc0c5796ea2d94bfb3df4a094d168 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 431 9.6E-83 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CWR56_RS13515 e6dcc0c5796ea2d94bfb3df4a094d168 519 Gene3D G3DSA:3.40.190.10 157 292 6.8E-40 T 29-03-2018 CWR56_RS02290 e17bb29a9fc3184ea12df4b6a642ddd2 379 Pfam PF02661 Fic/DOC family 122 220 6.2E-18 T 29-03-2018 IPR003812 Fido domain CWR56_RS02290 e17bb29a9fc3184ea12df4b6a642ddd2 379 SUPERFAMILY SSF140931 99 281 2.09E-32 T 29-03-2018 IPR003812 Fido domain CWR56_RS02290 e17bb29a9fc3184ea12df4b6a642ddd2 379 Gene3D G3DSA:1.10.3290.10 35 293 1.3E-48 T 29-03-2018 IPR003812 Fido domain CWR56_RS03105 b418770f08e3ceddbb5988563d1c186a 244 SMART SM00849 22 226 1.1E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS03105 b418770f08e3ceddbb5988563d1c186a 244 Gene3D G3DSA:3.60.15.10 25 230 3.1E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS03105 b418770f08e3ceddbb5988563d1c186a 244 Pfam PF00753 Metallo-beta-lactamase superfamily 27 226 4.2E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS03105 b418770f08e3ceddbb5988563d1c186a 244 SUPERFAMILY SSF56281 23 231 1.13E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS05115 7d1856a811cd54731d177119f801341b 200 SUPERFAMILY SSF52540 1 193 6.96E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05115 7d1856a811cd54731d177119f801341b 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 197 26.74 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWR56_RS05115 7d1856a811cd54731d177119f801341b 200 Pfam PF01121 Dephospho-CoA kinase 2 181 2.6E-55 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWR56_RS05115 7d1856a811cd54731d177119f801341b 200 Gene3D G3DSA:3.40.50.300 1 200 6.0E-44 T 29-03-2018 CWR56_RS05115 7d1856a811cd54731d177119f801341b 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 187 3.8E-55 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWR56_RS10125 b512db8a2be0de2c832168b7b506e276 448 Pfam PF01554 MatE 241 402 6.5E-33 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS10125 b512db8a2be0de2c832168b7b506e276 448 Pfam PF01554 MatE 19 178 2.0E-35 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS10125 b512db8a2be0de2c832168b7b506e276 448 PIRSF PIRSF006603 1 447 7.5E-132 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS10125 b512db8a2be0de2c832168b7b506e276 448 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 413 2.2E-83 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS10920 e4c201444a7b5816c06f5506da146391 76 Gene3D G3DSA:1.10.10.10 3 75 1.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS00895 9778d8908488f55da5cce432f2a675c1 377 Pfam PF05569 BlaR1 peptidase M56 9 276 2.2E-50 T 29-03-2018 IPR008756 Peptidase M56 CWR56_RS16650 839205186a9c2da03969ad601a4bd271 140 Pfam PF12646 Domain of unknown function (DUF3783) 78 131 2.3E-15 T 29-03-2018 IPR016621 Uncharacterised conserved protein UCP014543 CWR56_RS08220 75f83b536004f4ee40e69e2ba5138cb6 429 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 15 387 2.8E-22 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CWR56_RS01890 e8c3453c2d807ee7051bf99dce5017d4 266 SUPERFAMILY SSF53067 1 254 4.18E-41 T 29-03-2018 CWR56_RS01890 e8c3453c2d807ee7051bf99dce5017d4 266 Gene3D G3DSA:3.30.420.40 95 237 3.7E-41 T 29-03-2018 CWR56_RS01890 e8c3453c2d807ee7051bf99dce5017d4 266 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 2 250 4.4E-84 T 29-03-2018 IPR008275 CoA enzyme activase CWR56_RS01890 e8c3453c2d807ee7051bf99dce5017d4 266 Gene3D G3DSA:3.30.420.40 1 89 7.7E-4 T 29-03-2018 CWR56_RS01890 e8c3453c2d807ee7051bf99dce5017d4 266 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 252 4.7E-65 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR56_RS02950 95ef4d813ea33736ca8463af049217e1 91 SUPERFAMILY SSF46689 4 90 2.87E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS02950 95ef4d813ea33736ca8463af049217e1 91 Pfam PF08765 Mor transcription activator family 27 90 1.6E-8 T 29-03-2018 IPR014875 Mor transcription activator CWR56_RS02950 95ef4d813ea33736ca8463af049217e1 91 Gene3D G3DSA:1.10.10.60 50 91 1.0E-8 T 29-03-2018 CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 5.0E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 5.0E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 5.0E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 190 203 5.0E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 195 1.7E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 SUPERFAMILY SSF56784 4 229 3.8E-44 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 201 1.4E-28 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS01050 b139058697acaf252ab13b9110942c62 238 Gene3D G3DSA:3.40.50.1000 3 216 4.0E-33 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS05185 203d29d1b0853acd9b104a384193d6e7 194 SUPERFAMILY SSF52972 1 184 7.19E-61 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWR56_RS05185 203d29d1b0853acd9b104a384193d6e7 194 Pfam PF02545 Maf-like protein 3 184 2.2E-58 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CWR56_RS05185 203d29d1b0853acd9b104a384193d6e7 194 Gene3D G3DSA:3.90.950.10 1 191 5.1E-67 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWR56_RS05185 203d29d1b0853acd9b104a384193d6e7 194 Hamap MF_00528 Septum formation protein Maf [maf]. 2 189 31.879 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CWR56_RS05185 203d29d1b0853acd9b104a384193d6e7 194 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 183 7.9E-57 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CWR56_RS05185 203d29d1b0853acd9b104a384193d6e7 194 PIRSF PIRSF006305 1 190 1.6E-57 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 SUPERFAMILY SSF52172 1 123 5.98E-26 T 29-03-2018 IPR011006 CheY-like superfamily CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 SMART SM00850 142 240 1.7E-16 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 Pfam PF00072 Response regulator receiver domain 4 113 3.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 Gene3D G3DSA:2.40.50.40 133 202 3.7E-16 T 29-03-2018 CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 SMART SM00448 2 113 4.4E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 Pfam PF04397 LytTr DNA-binding domain 143 230 7.5E-16 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR56_RS01770 008952f5b3bd68c67f17b8b0532afe73 245 Gene3D G3DSA:3.40.50.2300 1 132 6.7E-26 T 29-03-2018 CWR56_RS03175 1e29f91288c13be7aaa1ac1fc49b63ee 253 Pfam PF12730 ABC-2 family transporter protein 6 183 6.5E-19 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS16490 2898ffb5f3e47b13908cee390447c222 159 SUPERFAMILY SSF52728 1 158 5.23E-41 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS16490 2898ffb5f3e47b13908cee390447c222 159 Gene3D G3DSA:3.40.35.10 1 159 9.1E-47 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS16490 2898ffb5f3e47b13908cee390447c222 159 Pfam PF03830 PTS system sorbose subfamily IIB component 2 151 1.2E-43 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS03385 7791be29e85f0ab80617090972955c5c 192 SUPERFAMILY SSF109604 3 133 4.28E-18 T 29-03-2018 CWR56_RS03385 7791be29e85f0ab80617090972955c5c 192 SMART SM00471 14 128 0.0069 T 29-03-2018 IPR003607 HD/PDEase domain CWR56_RS03385 7791be29e85f0ab80617090972955c5c 192 Gene3D G3DSA:1.10.3210.10 2 186 2.8E-15 T 29-03-2018 CWR56_RS03385 7791be29e85f0ab80617090972955c5c 192 Pfam PF01966 HD domain 20 108 4.5E-10 T 29-03-2018 IPR006674 HD domain CWR56_RS03385 7791be29e85f0ab80617090972955c5c 192 TIGRFAM TIGR00277 HDIG: HDIG domain 18 95 3.9E-8 T 29-03-2018 IPR006675 HDIG domain CWR56_RS03345 695dd324338d91dabcdea9c243604e16 458 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 35 427 3.8E-104 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CWR56_RS03345 695dd324338d91dabcdea9c243604e16 458 Pfam PF02386 Cation transport protein 17 435 3.7E-59 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 SUPERFAMILY SSF52402 71 264 2.86E-52 T 29-03-2018 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 Gene3D G3DSA:3.40.50.1220 266 396 1.5E-46 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 Gene3D G3DSA:3.40.50.620 65 264 1.3E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 SUPERFAMILY SSF54862 3 56 1.47E-6 T 29-03-2018 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 Pfam PF01012 Electron transfer flavoprotein domain 74 246 9.0E-39 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 Gene3D G3DSA:3.30.70.20 4 64 5.8E-5 T 29-03-2018 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 271 352 3.6E-30 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 PIRSF PIRSF000089 68 395 5.1E-97 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 SUPERFAMILY SSF52467 270 390 1.55E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS05330 519b9215f0e01c6c4ed3f099905f2827 406 SMART SM00893 72 266 4.5E-39 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CWR56_RS07410 36e93ccc311fd37bfe53288197288f17 253 Pfam PF01863 Protein of unknown function DUF45 30 246 4.0E-52 T 29-03-2018 IPR002725 Protein of unknown function DUF45 CWR56_RS04860 229e9e9fd290dcbd3a7e0b7e15c7ef52 265 Gene3D G3DSA:3.90.226.10 8 225 1.3E-76 T 29-03-2018 CWR56_RS04860 229e9e9fd290dcbd3a7e0b7e15c7ef52 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CWR56_RS04860 229e9e9fd290dcbd3a7e0b7e15c7ef52 265 SUPERFAMILY SSF52096 9 262 1.64E-88 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CWR56_RS04860 229e9e9fd290dcbd3a7e0b7e15c7ef52 265 Gene3D G3DSA:1.10.12.10 226 262 8.6E-20 T 29-03-2018 IPR014748 Crontonase, C-terminal CWR56_RS04860 229e9e9fd290dcbd3a7e0b7e15c7ef52 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 262 1.7E-71 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CWR56_RS13245 1b6cddcb481a0cb308dda1cd4976e0ff 85 Pfam PF02325 YGGT family 9 81 4.0E-18 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 CWR56_RS07750 f07126df81ee8d6f60a425c4c9e9a19d 178 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 168 1.2E-31 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CWR56_RS18070 5539982e98fd1bf73dde78a7b92c3c74 127 SUPERFAMILY SSF54593 4 126 8.28E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS18070 5539982e98fd1bf73dde78a7b92c3c74 127 Gene3D G3DSA:3.10.180.10 1 127 4.8E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR56_RS18070 5539982e98fd1bf73dde78a7b92c3c74 127 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 124 5.9E-6 T 29-03-2018 IPR028973 PhnB-like CWR56_RS06520 9058baac8ed9754b8092d0e516e1a715 147 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 39 133 2.0E-4 T 29-03-2018 CWR56_RS06520 9058baac8ed9754b8092d0e516e1a715 147 Pfam PF14184 Regulatory protein YrvL 14 138 2.8E-34 T 29-03-2018 IPR025912 Regulatory protein YrvL CWR56_RS16320 1b441eeb5f8226b99ac97a9b2d222647 437 SUPERFAMILY SSF142984 256 307 1.83E-6 T 29-03-2018 CWR56_RS16320 1b441eeb5f8226b99ac97a9b2d222647 437 Gene3D G3DSA:2.40.50.100 10 38 0.3 T 29-03-2018 CWR56_RS16320 1b441eeb5f8226b99ac97a9b2d222647 437 SUPERFAMILY SSF142019 67 244 2.48E-45 T 29-03-2018 CWR56_RS16320 1b441eeb5f8226b99ac97a9b2d222647 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 83 226 1.6E-36 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR56_RS16320 1b441eeb5f8226b99ac97a9b2d222647 437 Pfam PF13375 RnfC Barrel sandwich hybrid domain 4 61 1.6E-14 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain CWR56_RS16320 1b441eeb5f8226b99ac97a9b2d222647 437 TIGRFAM TIGR04481 PR_assoc_PrdC: proline reductase-associated electron transfer protein PrdC 5 429 6.4E-212 T 29-03-2018 IPR031001 Proline reductase-associated electron transfer protein PrdC CWR56_RS01455 4b046c59a542299acfdc3e4c948fc53f 134 Pfam PF03610 PTS system fructose IIA component 3 115 1.0E-27 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01455 4b046c59a542299acfdc3e4c948fc53f 134 Gene3D G3DSA:3.40.50.510 1 134 2.5E-38 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS01455 4b046c59a542299acfdc3e4c948fc53f 134 SUPERFAMILY SSF53062 2 131 1.96E-37 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR56_RS07790 38fd206f5c77f1ff44434401f84d1382 209 Gene3D G3DSA:2.60.60.30 18 199 2.2E-52 T 29-03-2018 CWR56_RS07790 38fd206f5c77f1ff44434401f84d1382 209 Pfam PF02342 TerD domain 1 198 4.4E-73 T 29-03-2018 IPR003325 TerD domain GO:0006950 CWR56_RS01775 efd75149c48fc3f8dbe442bdb37b6135 1685 Pfam PF13569 Domain of unknown function (DUF4132) 1318 1494 7.9E-51 T 29-03-2018 IPR025406 Domain of unknown function DUF4132 CWR56_RS06865 9bf5902299c20402832e48d6f30a442d 155 SUPERFAMILY SSF50475 1 153 5.12E-49 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS06865 9bf5902299c20402832e48d6f30a442d 155 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 152 2.4E-19 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CWR56_RS06865 9bf5902299c20402832e48d6f30a442d 155 Gene3D G3DSA:2.30.110.10 4 153 1.3E-32 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS13270 9f8d53b9b9525c9b1e98da8c27bd63f3 451 Hamap MF_01221 UPF0210 protein . 1 451 53.129 T 29-03-2018 IPR007841 Uncharacterised protein family UPF0210 CWR56_RS13270 9f8d53b9b9525c9b1e98da8c27bd63f3 451 SUPERFAMILY SSF51998 2 446 4.76E-183 T 29-03-2018 CWR56_RS13270 9f8d53b9b9525c9b1e98da8c27bd63f3 451 Pfam PF05167 Uncharacterised ACR (DUF711) 12 415 2.1E-182 T 29-03-2018 IPR007841 Uncharacterised protein family UPF0210 CWR56_RS13270 9f8d53b9b9525c9b1e98da8c27bd63f3 451 Gene3D G3DSA:3.20.70.20 13 428 1.9E-186 T 29-03-2018 CWR56_RS09745 a1e573f79cda85d663292c084f745c80 441 Pfam PF01554 MatE 243 399 4.0E-17 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS09745 a1e573f79cda85d663292c084f745c80 441 Pfam PF01554 MatE 19 179 3.5E-22 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS09745 a1e573f79cda85d663292c084f745c80 441 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 414 1.2E-50 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS09745 a1e573f79cda85d663292c084f745c80 441 PIRSF PIRSF006603 3 441 5.9E-63 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS03520 1b848249fe71300d6de1c13550d62ca3 268 SUPERFAMILY SSF51717 4 260 1.31E-65 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS03520 1b848249fe71300d6de1c13550d62ca3 268 Pfam PF00809 Pterin binding enzyme 17 231 2.0E-26 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS03520 1b848249fe71300d6de1c13550d62ca3 268 Gene3D G3DSA:3.20.20.20 1 264 1.2E-41 T 29-03-2018 CWR56_RS14730 a4f682deee21612c9bad98e9e86d6e12 103 Gene3D G3DSA:1.20.5.620 6 74 3.8E-4 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CWR56_RS14210 786787674e315985878a81567189e208 126 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 12 125 4.1E-29 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CWR56_RS14210 786787674e315985878a81567189e208 126 Pfam PF12670 Protein of unknown function (DUF3792) 12 122 2.7E-25 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CWR56_RS11070 1fcefecf02b3bbbec6275d8f6e9db8ce 167 Pfam PF07275 Antirestriction protein (ArdA) 7 163 8.6E-40 T 29-03-2018 IPR009899 Antirestriction CWR56_RS15245 809a27d51d3fd89ac315fa7cb9768e22 158 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 14 135 5.4E-36 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS15245 809a27d51d3fd89ac315fa7cb9768e22 158 SUPERFAMILY SSF51261 3 144 2.62E-40 T 29-03-2018 IPR011055 Duplicated hybrid motif CWR56_RS15245 809a27d51d3fd89ac315fa7cb9768e22 158 Gene3D G3DSA:2.70.70.10 2 155 3.1E-39 T 29-03-2018 CWR56_RS15245 809a27d51d3fd89ac315fa7cb9768e22 158 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 15 125 6.6E-32 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR56_RS02490 4534c798c369f2d8abcc0ec9c9671b52 198 Pfam PF01339 CheB methylesterase 9 187 1.8E-55 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CWR56_RS02490 4534c798c369f2d8abcc0ec9c9671b52 198 SUPERFAMILY SSF52738 7 191 7.72E-64 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CWR56_RS02490 4534c798c369f2d8abcc0ec9c9671b52 198 Gene3D G3DSA:3.40.50.180 2 197 3.9E-67 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CWR56_RS12790 5dc956577cd82151222eff7a8a775233 272 Gene3D G3DSA:1.10.10.60 51 209 0.038 T 29-03-2018 CWR56_RS12790 5dc956577cd82151222eff7a8a775233 272 Pfam PF12833 Helix-turn-helix domain 179 256 1.4E-10 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12790 5dc956577cd82151222eff7a8a775233 272 SMART SM00342 172 257 0.0019 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR56_RS12790 5dc956577cd82151222eff7a8a775233 272 Gene3D G3DSA:1.10.10.60 212 261 0.0045 T 29-03-2018 CWR56_RS06720 e6fb4ce9576986cb24ee4b3245571bea 274 Pfam PF01522 Polysaccharide deacetylase 79 201 2.4E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS06720 e6fb4ce9576986cb24ee4b3245571bea 274 Gene3D G3DSA:3.20.20.370 46 273 1.0E-51 T 29-03-2018 CWR56_RS06720 e6fb4ce9576986cb24ee4b3245571bea 274 SUPERFAMILY SSF88713 70 268 7.34E-60 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS06720 e6fb4ce9576986cb24ee4b3245571bea 274 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 48 270 2.5E-93 T 29-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA CWR56_RS16330 46e7ec329d5acc617fd31dad894d4b89 254 Gene3D G3DSA:3.20.20.370 32 247 2.9E-57 T 29-03-2018 CWR56_RS16330 46e7ec329d5acc617fd31dad894d4b89 254 SUPERFAMILY SSF88713 20 237 3.78E-62 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS16330 46e7ec329d5acc617fd31dad894d4b89 254 Pfam PF01522 Polysaccharide deacetylase 50 171 3.2E-37 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS15010 c60109fb4a12ce1f7f41d6cd05970ea0 425 Gene3D G3DSA:1.20.1250.20 1 239 0.0015 T 29-03-2018 CWR56_RS15010 c60109fb4a12ce1f7f41d6cd05970ea0 425 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 221 7.8E-55 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CWR56_RS15010 c60109fb4a12ce1f7f41d6cd05970ea0 425 Pfam PF08534 Redoxin 287 411 2.3E-31 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CWR56_RS15010 c60109fb4a12ce1f7f41d6cd05970ea0 425 SUPERFAMILY SSF52833 286 421 1.22E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CWR56_RS15010 c60109fb4a12ce1f7f41d6cd05970ea0 425 Gene3D G3DSA:3.40.30.10 240 425 1.3E-41 T 29-03-2018 CWR56_RS15010 c60109fb4a12ce1f7f41d6cd05970ea0 425 ProSitePatterns PS00194 Thioredoxin family active site. 309 327 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWR56_RS11875 b75b4288d1e5cdadc00f4fec4059c039 27 ProDom PD018707 LEADER PEPTIDE METHYLASE PLASMID RESISTANCE RRNA METHYLTRANSFERASE ERMB 23S ANTIBIOTIC 1 27 3.0E-8 T 29-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWR56_RS11875 b75b4288d1e5cdadc00f4fec4059c039 27 Pfam PF06308 23S rRNA methylase leader peptide (ErmC) 1 27 1.2E-15 T 29-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWR56_RS17080 6441bf4211251f43975ff142c7d6fec5 202 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 184 1.6E-23 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17080 6441bf4211251f43975ff142c7d6fec5 202 SUPERFAMILY SSF53790 1 200 2.18E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17080 6441bf4211251f43975ff142c7d6fec5 202 Gene3D G3DSA:3.30.950.10 111 202 2.3E-19 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS17080 6441bf4211251f43975ff142c7d6fec5 202 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 197 5.9E-53 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CWR56_RS17080 6441bf4211251f43975ff142c7d6fec5 202 Gene3D G3DSA:3.40.1010.10 1 110 1.4E-15 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 264 5.6E-71 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 Gene3D G3DSA:3.40.50.1000 110 273 3.5E-31 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 Gene3D G3DSA:3.40.50.1000 1 109 1.1E-17 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 237 8.5E-29 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 264 3.5E-63 T 29-03-2018 IPR000150 Cof family GO:0016787 CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 SUPERFAMILY SSF56784 1 269 2.59E-74 T 29-03-2018 IPR023214 HAD-like domain CWR56_RS11715 089af7162eaf72a80cfabf2fa11edaf2 273 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 29-03-2018 CWR56_RS14125 253f5ddb1d38a22a0898c49d80d88f6c 370 Pfam PF16401 Domain of unknown function (DUF5009) 5 101 2.0E-10 T 29-03-2018 IPR032176 Domain of unknown function DUF5009 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 SUPERFAMILY SSF51445 5 476 2.29E-150 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 2.4E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 313 327 2.4E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 382 2.4E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 2.4E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 2.4E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 Gene3D G3DSA:3.20.20.80 4 481 4.6E-141 T 29-03-2018 CWR56_RS15380 42c34b83ac6722dadc3eacb415cb94fb 481 Pfam PF00232 Glycosyl hydrolase family 1 6 475 4.7E-121 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR56_RS18060 fc6684ae8ba7f9431da14c4477dffec2 472 Pfam PF00999 Sodium/hydrogen exchanger family 7 382 5.9E-46 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR56_RS18060 fc6684ae8ba7f9431da14c4477dffec2 472 Pfam PF02080 TrkA-C domain 408 465 2.2E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS18060 fc6684ae8ba7f9431da14c4477dffec2 472 Gene3D G3DSA:3.30.70.1450 401 472 2.2E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS18060 fc6684ae8ba7f9431da14c4477dffec2 472 SUPERFAMILY SSF116726 407 465 1.06E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR56_RS08930 d9795dc30bb98e726b8852c7955b4099 282 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 5 225 3.2E-51 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain CWR56_RS08930 d9795dc30bb98e726b8852c7955b4099 282 SUPERFAMILY SSF52266 2 275 5.8E-76 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR56_RS08930 d9795dc30bb98e726b8852c7955b4099 282 Gene3D G3DSA:3.40.50.1110 1 247 6.4E-48 T 29-03-2018 CWR56_RS10280 e5cf1d47f143208cb70fb56b46b78c17 259 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 215 241 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CWR56_RS10280 e5cf1d47f143208cb70fb56b46b78c17 259 Pfam PF01148 Cytidylyltransferase family 3 257 5.3E-57 T 29-03-2018 CWR56_RS05870 d0fd091c993d8fdd9fb1cd54350cbf71 311 Pfam PF13732 Domain of unknown function (DUF4162) 237 304 1.6E-6 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CWR56_RS05870 d0fd091c993d8fdd9fb1cd54350cbf71 311 Gene3D G3DSA:3.40.50.300 1 262 5.3E-67 T 29-03-2018 CWR56_RS05870 d0fd091c993d8fdd9fb1cd54350cbf71 311 SMART SM00382 28 220 9.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS05870 d0fd091c993d8fdd9fb1cd54350cbf71 311 Pfam PF00005 ABC transporter 19 162 6.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS05870 d0fd091c993d8fdd9fb1cd54350cbf71 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS05870 d0fd091c993d8fdd9fb1cd54350cbf71 311 SUPERFAMILY SSF52540 4 222 1.6E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS18350 fa1b871c0d89a365869d164220bccc9d 398 SUPERFAMILY SSF53383 4 392 4.84E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS18350 fa1b871c0d89a365869d164220bccc9d 398 Gene3D G3DSA:3.40.640.10 44 296 1.3E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS18350 fa1b871c0d89a365869d164220bccc9d 398 Pfam PF00155 Aminotransferase class I and II 47 384 3.7E-38 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS18350 fa1b871c0d89a365869d164220bccc9d 398 Gene3D G3DSA:3.90.1150.10 297 394 1.1E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 420 434 1.2E-13 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 219 1.2E-13 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 380 396 1.2E-13 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 223 236 1.2E-13 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 SUPERFAMILY SSF50249 15 105 7.95E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 465 4.6E-189 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 8 465 45.826 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 Pfam PF01336 OB-fold nucleic acid binding domain 23 99 6.6E-9 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 SUPERFAMILY SSF55681 106 463 1.84E-98 T 29-03-2018 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 Gene3D G3DSA:3.30.930.10 127 461 8.9E-95 T 29-03-2018 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 459 7.1E-85 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR56_RS10865 1625e146ff69363002a7b7f098274821 465 Gene3D G3DSA:2.40.50.140 2 110 6.6E-20 T 29-03-2018 CWR56_RS15670 7bab4d27c37c0c4cb5162e483d49d35d 66 SMART SM00530 4 59 4.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15670 7bab4d27c37c0c4cb5162e483d49d35d 66 Pfam PF01381 Helix-turn-helix 5 57 1.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS15670 7bab4d27c37c0c4cb5162e483d49d35d 66 Gene3D G3DSA:1.10.3100.10 1 66 2.6E-18 T 29-03-2018 IPR027910 YdiL-like domain CWR56_RS15670 7bab4d27c37c0c4cb5162e483d49d35d 66 SUPERFAMILY SSF47413 2 61 1.05E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS02620 e5f56489616fa63b87ece8700fcccbb1 282 Gene3D G3DSA:3.40.50.10170 1 153 3.6E-46 T 29-03-2018 CWR56_RS02620 e5f56489616fa63b87ece8700fcccbb1 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 279 1.0E-78 T 29-03-2018 IPR003797 DegV CWR56_RS02620 e5f56489616fa63b87ece8700fcccbb1 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 1.9E-92 T 29-03-2018 IPR003797 DegV CWR56_RS02620 e5f56489616fa63b87ece8700fcccbb1 282 SUPERFAMILY SSF82549 1 278 1.73E-77 T 29-03-2018 CWR56_RS02620 e5f56489616fa63b87ece8700fcccbb1 282 Gene3D G3DSA:3.30.1180.10 154 280 6.4E-33 T 29-03-2018 CWR56_RS14215 e4559208715f8dc399e5e156014750ba 97 SMART SM01323 5 88 5.0E-37 T 29-03-2018 IPR003849 Preprotein translocase YajC CWR56_RS14215 e4559208715f8dc399e5e156014750ba 97 PRINTS PR01853 Bacterial YajC preprotein translocase signature 7 27 2.1E-13 T 29-03-2018 IPR003849 Preprotein translocase YajC CWR56_RS14215 e4559208715f8dc399e5e156014750ba 97 PRINTS PR01853 Bacterial YajC preprotein translocase signature 45 63 2.1E-13 T 29-03-2018 IPR003849 Preprotein translocase YajC CWR56_RS14215 e4559208715f8dc399e5e156014750ba 97 Pfam PF02699 Preprotein translocase subunit 10 85 1.2E-28 T 29-03-2018 IPR003849 Preprotein translocase YajC CWR56_RS14215 e4559208715f8dc399e5e156014750ba 97 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 12 87 3.6E-24 T 29-03-2018 IPR003849 Preprotein translocase YajC CWR56_RS06765 274aa72a48366e9ba22b96bc49900929 123 Pfam PF03788 LrgA family 14 108 1.9E-26 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CWR56_RS05550 3f0b628b87ba49e4b2fd4f44c918ba8d 373 Pfam PF12555 Thiamine pyrophosphokinase C terminal 320 370 3.8E-14 T 29-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CWR56_RS05550 3f0b628b87ba49e4b2fd4f44c918ba8d 373 SUPERFAMILY SSF63999 139 323 5.36E-31 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS05550 3f0b628b87ba49e4b2fd4f44c918ba8d 373 Gene3D G3DSA:3.40.50.10240 167 302 1.8E-12 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR56_RS01190 a10d1d2a78e116d9cf3b2bbfd564a48a 119 PIRSF PIRSF039090 3 119 5.2E-24 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS01190 a10d1d2a78e116d9cf3b2bbfd564a48a 119 SUPERFAMILY SSF101116 12 117 2.75E-25 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS01190 a10d1d2a78e116d9cf3b2bbfd564a48a 119 TIGRFAM TIGR00208 fliS: flagellar protein FliS 13 114 1.2E-15 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS01190 a10d1d2a78e116d9cf3b2bbfd564a48a 119 Gene3D G3DSA:1.20.120.340 5 117 3.5E-25 T 29-03-2018 CWR56_RS01190 a10d1d2a78e116d9cf3b2bbfd564a48a 119 Pfam PF02561 Flagellar protein FliS 10 113 3.9E-25 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CWR56_RS08190 b80a9045a87a1d561939e71907b5aa7d 112 Gene3D G3DSA:3.30.110.70 1 103 3.8E-34 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CWR56_RS08190 b80a9045a87a1d561939e71907b5aa7d 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.584 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CWR56_RS08190 b80a9045a87a1d561939e71907b5aa7d 112 Pfam PF01906 Putative heavy-metal-binding 1 102 9.2E-37 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CWR56_RS08190 b80a9045a87a1d561939e71907b5aa7d 112 SUPERFAMILY SSF117782 1 105 2.62E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CWR56_RS01565 5fe516ff85906876258c7ae5afeb2cd3 247 Gene3D G3DSA:3.40.50.880 1 246 1.8E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS01565 5fe516ff85906876258c7ae5afeb2cd3 247 SUPERFAMILY SSF52317 3 246 2.75E-68 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS01565 5fe516ff85906876258c7ae5afeb2cd3 247 Pfam PF07090 Putative glutamine amidotransferase 3 247 9.4E-124 T 29-03-2018 IPR010768 Putative glutamine amidotransferase CWR56_RS01565 5fe516ff85906876258c7ae5afeb2cd3 247 PIRSF PIRSF034405 1 247 1.1E-103 T 29-03-2018 IPR017027 Uncharacterised conserved protein UCP034405 CWR56_RS14770 1627b8a5aa6002f02b249bfa68942694 291 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 146 251 2.0E-7 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CWR56_RS14770 1627b8a5aa6002f02b249bfa68942694 291 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 7 121 1.9E-31 T 29-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal CWR56_RS14770 1627b8a5aa6002f02b249bfa68942694 291 Gene3D G3DSA:3.40.50.720 152 290 4.1E-11 T 29-03-2018 CWR56_RS14770 1627b8a5aa6002f02b249bfa68942694 291 Gene3D G3DSA:3.40.50.720 4 151 3.5E-8 T 29-03-2018 CWR56_RS14770 1627b8a5aa6002f02b249bfa68942694 291 SUPERFAMILY SSF51735 136 245 1.03E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 SUPERFAMILY SSF56235 5 537 1.29E-162 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 24 522 2.9E-109 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 Pfam PF01019 Gamma-glutamyltranspeptidase 37 530 2.1E-145 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 381 399 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 283 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 357 375 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 427 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS07265 89be74616432b3a48daa10d057234fb3 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 9.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR56_RS11100 f2a811c7d23326cc6896b0a0b02ab759 44 Pfam PF12664 Protein of unknown function (DUF3789) 4 35 4.5E-16 T 29-03-2018 IPR024522 Protein of unknown function DUF3789 CWR56_RS01960 a699fd54eda09d787e8e496a6d35dff0 162 Pfam PF02486 Replication initiation factor 1 135 9.2E-38 T 29-03-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 CWR56_RS11120 0241a35340cbf1fcaca43470593c830f 180 Pfam PF12675 Protein of unknown function (DUF3795) 28 66 2.4E-5 T 29-03-2018 IPR024227 Protein of unknown function DUF3795 CWR56_RS13060 61e41a5146df436061704f597b86a28a 250 PIRSF PIRSF006594 4 243 2.9E-53 T 29-03-2018 IPR002829 Protein of unknown function DUF116 CWR56_RS13060 61e41a5146df436061704f597b86a28a 250 Pfam PF01976 Protein of unknown function DUF116 85 238 4.8E-55 T 29-03-2018 IPR002829 Protein of unknown function DUF116 CWR56_RS02985 f6ed9e67c95413f5e0fc96941c60892e 122 SUPERFAMILY SSF54427 4 118 3.62E-23 T 29-03-2018 IPR032710 NTF2-like domain CWR56_RS02985 f6ed9e67c95413f5e0fc96941c60892e 122 Gene3D G3DSA:3.10.450.50 2 115 2.2E-5 T 29-03-2018 CWR56_RS07560 0c47c672868ef924c7102ab66ce58a02 208 PIRSF PIRSF001296 1 206 6.5E-72 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR56_RS07560 0c47c672868ef924c7102ab66ce58a02 208 Pfam PF02669 K+-transporting ATPase, c chain 5 201 2.8E-70 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR56_RS07560 0c47c672868ef924c7102ab66ce58a02 208 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 204 32.547 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR56_RS07560 0c47c672868ef924c7102ab66ce58a02 208 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 3 201 1.2E-49 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR56_RS13555 c4836a766be909218999c68ed59f4e3a 444 Pfam PF02447 GntP family permease 7 439 2.5E-14 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR56_RS12875 e2bbf4c43ab0d8a8371cb668e798838c 582 Pfam PF13320 Domain of unknown function (DUF4091) 460 526 4.3E-25 T 29-03-2018 IPR025150 Domain of unknown function DUF4091 CWR56_RS03480 4f2167f09e7df0821f160bcc556d5744 210 Pfam PF04961 Formiminotransferase-cyclodeaminase 7 187 2.9E-70 T 29-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CWR56_RS03480 4f2167f09e7df0821f160bcc556d5744 210 SUPERFAMILY SSF101262 3 208 1.57E-60 T 29-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CWR56_RS12900 13167b58ba5255ae2d9db2f3cfb0a3c6 246 Gene3D G3DSA:3.40.50.10490 3 241 6.9E-42 T 29-03-2018 CWR56_RS12900 13167b58ba5255ae2d9db2f3cfb0a3c6 246 Pfam PF13580 SIS domain 4 139 4.7E-37 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR56_RS12900 13167b58ba5255ae2d9db2f3cfb0a3c6 246 SUPERFAMILY SSF53697 5 202 2.22E-20 T 29-03-2018 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 Pfam PF01632 Ribosomal protein L35 2 62 4.4E-25 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 2.2E-26 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.3E-20 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.3E-20 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.3E-20 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 SUPERFAMILY SSF143034 2 64 6.28E-23 T 29-03-2018 CWR56_RS03285 3caf58e093aa0288f08c91e8329e5906 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.256 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR56_RS13575 69ddc8525ac43cdf360a574306a6fc9e 189 PIRSF PIRSF010130 1 189 4.6E-86 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CWR56_RS13575 69ddc8525ac43cdf360a574306a6fc9e 189 Pfam PF06130 Phosphate propanoyltransferase 4 83 8.2E-27 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CWR56_RS13575 69ddc8525ac43cdf360a574306a6fc9e 189 Pfam PF06130 Phosphate propanoyltransferase 112 178 6.9E-19 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CWR56_RS13575 69ddc8525ac43cdf360a574306a6fc9e 189 Gene3D G3DSA:2.40.40.20 54 161 0.0015 T 29-03-2018 CWR56_RS16335 5227c1ad7c5816789a696372c80631ee 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CWR56_RS16335 5227c1ad7c5816789a696372c80631ee 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 64 2.9E-26 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CWR56_RS09890 6db6759b61e76b1eefe8e933001c34df 191 Gene3D G3DSA:2.40.40.10 24 188 2.5E-10 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CWR56_RS13685 9f92e46def046c016dd922260fa65d9a 447 Pfam PF00860 Permease family 36 407 1.0E-42 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS13685 9f92e46def046c016dd922260fa65d9a 447 PIRSF PIRSF005353 11 447 3.0E-152 T 29-03-2018 IPR026033 Purine permease PbuG-like CWR56_RS13540 356a48989db7746db825b2f99a004967 218 Gene3D G3DSA:3.40.1080.10 1 217 2.4E-80 T 29-03-2018 CWR56_RS13540 356a48989db7746db825b2f99a004967 218 Pfam PF01144 Coenzyme A transferase 6 214 1.0E-64 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CWR56_RS13540 356a48989db7746db825b2f99a004967 218 SMART SM00882 4 215 3.5E-72 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CWR56_RS13540 356a48989db7746db825b2f99a004967 218 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 3 214 9.3E-67 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CWR56_RS13540 356a48989db7746db825b2f99a004967 218 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 16 31 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CWR56_RS13540 356a48989db7746db825b2f99a004967 218 SUPERFAMILY SSF100950 2 216 4.03E-78 T 29-03-2018 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00412 Epoxide hydrolase signature 244 266 6.1E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00412 Epoxide hydrolase signature 48 63 6.1E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00412 Epoxide hydrolase signature 28 46 6.1E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00412 Epoxide hydrolase signature 211 227 6.1E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 SUPERFAMILY SSF53474 1 268 3.4E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 4.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 4.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 4.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 Gene3D G3DSA:3.40.50.1820 2 269 3.6E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS14555 66e52a6e72f3964cd2d7ec391573803a 269 Pfam PF00561 alpha/beta hydrolase fold 23 255 7.2E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS01175 716bb88c1a48a31d6df3ec8a92ac282f 130 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 2 126 24.589 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CWR56_RS01175 716bb88c1a48a31d6df3ec8a92ac282f 130 SUPERFAMILY SSF141457 4 124 2.48E-40 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain CWR56_RS01175 716bb88c1a48a31d6df3ec8a92ac282f 130 Pfam PF02623 FliW protein 5 123 2.3E-38 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CWR56_RS01175 716bb88c1a48a31d6df3ec8a92ac282f 130 Gene3D G3DSA:2.30.290.10 2 129 4.3E-42 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain CWR56_RS00725 ecec6e98495a07b3cae2bbbfcb128970 158 Gene3D G3DSA:3.40.630.30 3 158 6.9E-36 T 29-03-2018 CWR56_RS00725 ecec6e98495a07b3cae2bbbfcb128970 158 Pfam PF13673 Acetyltransferase (GNAT) domain 22 133 5.3E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS00725 ecec6e98495a07b3cae2bbbfcb128970 158 SUPERFAMILY SSF55729 11 155 1.66E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS00725 ecec6e98495a07b3cae2bbbfcb128970 158 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 21 151 2.9E-45 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CWR56_RS08330 b172a9b353a475671e3f5821d0676bd3 415 Pfam PF02447 GntP family permease 8 410 5.3E-16 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR56_RS12590 70ffbe31f9a8ae43ed06e278907d3d67 314 SUPERFAMILY SSF51182 1 313 8.9E-105 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS12590 70ffbe31f9a8ae43ed06e278907d3d67 314 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 313 3.1E-75 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CWR56_RS12590 70ffbe31f9a8ae43ed06e278907d3d67 314 PIRSF PIRSF036894 1 314 2.3E-132 T 29-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CWR56_RS12590 70ffbe31f9a8ae43ed06e278907d3d67 314 Gene3D G3DSA:2.60.120.10 235 314 6.8E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS12590 70ffbe31f9a8ae43ed06e278907d3d67 314 Pfam PF01238 Phosphomannose isomerase type I 4 313 1.9E-46 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CWR56_RS12590 70ffbe31f9a8ae43ed06e278907d3d67 314 Gene3D G3DSA:2.60.120.10 1 222 4.3E-63 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS03135 ce9bd7f98cd021335fc10239a57b7d84 166 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 21 164 3.3E-45 T 29-03-2018 IPR006480 Bacteriophage holin family CWR56_RS03135 ce9bd7f98cd021335fc10239a57b7d84 166 Pfam PF05105 Bacteriophage holin family 32 152 1.0E-24 T 29-03-2018 IPR006480 Bacteriophage holin family CWR56_RS07800 4a29c93b9421a17700511710f2e96443 520 Pfam PF14266 Putative component of 'biosynthetic module' 26 504 1.0E-142 T 29-03-2018 IPR025647 Putative component of 'biosynthetic module' CWR56_RS11740 91b5f1afd682ceeeffc6b08a049e8ba3 209 SUPERFAMILY SSF161098 72 206 8.11E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS11740 91b5f1afd682ceeeffc6b08a049e8ba3 209 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 205 4.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS11740 91b5f1afd682ceeeffc6b08a049e8ba3 209 Gene3D G3DSA:1.10.3720.10 24 209 2.1E-20 T 29-03-2018 CWR56_RS15075 a50a4048a8a1d299d20d42a4fc2a3654 448 Pfam PF12708 Pectate lyase superfamily protein 10 203 1.3E-23 T 29-03-2018 IPR024535 Pectate lyase superfamily protein CWR56_RS15075 a50a4048a8a1d299d20d42a4fc2a3654 448 Gene3D G3DSA:2.160.20.10 2 420 4.2E-9 T 29-03-2018 IPR012334 Pectin lyase fold CWR56_RS15075 a50a4048a8a1d299d20d42a4fc2a3654 448 SUPERFAMILY SSF51126 7 253 1.07E-7 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 Gene3D G3DSA:3.40.50.300 223 361 2.1E-44 T 29-03-2018 CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 Pfam PF00270 DEAD/DEAH box helicase 29 192 3.1E-52 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 Pfam PF00271 Helicase conserved C-terminal domain 230 338 7.0E-30 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 SMART SM00490 257 338 2.4E-33 T 29-03-2018 IPR001650 Helicase, C-terminal CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 Gene3D G3DSA:3.40.50.300 1 222 1.2E-61 T 29-03-2018 CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 Gene3D G3DSA:3.30.70.330 362 537 0.0022 T 29-03-2018 CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 SMART SM00487 23 221 4.1E-65 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 SUPERFAMILY SSF52540 72 359 2.13E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CWR56_RS03695 f34c44dcf050bb66616e456f92fb84d5 537 Pfam PF03880 DbpA RNA binding domain 460 530 2.7E-25 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CWR56_RS11205 05415b752cd3351b4c62449a020b2827 460 Pfam PF00854 POT family 114 215 7.7E-15 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CWR56_RS11205 05415b752cd3351b4c62449a020b2827 460 Pfam PF00854 POT family 246 427 9.9E-29 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CWR56_RS11205 05415b752cd3351b4c62449a020b2827 460 SUPERFAMILY SSF103473 11 454 1.44E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS11205 05415b752cd3351b4c62449a020b2827 460 Gene3D G3DSA:1.20.1250.20 235 457 2.6E-15 T 29-03-2018 CWR56_RS11205 05415b752cd3351b4c62449a020b2827 460 Gene3D G3DSA:1.20.1250.20 7 218 6.3E-25 T 29-03-2018 CWR56_RS13275 98e95ac5644e2542bfed92ef03297faf 89 Pfam PF13740 ACT domain 4 77 1.7E-11 T 29-03-2018 CWR56_RS13275 98e95ac5644e2542bfed92ef03297faf 89 Hamap MF_01054 UPF0237 protein . 1 89 24.765 T 29-03-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type CWR56_RS13275 98e95ac5644e2542bfed92ef03297faf 89 Gene3D G3DSA:3.30.70.260 1 84 5.5E-19 T 29-03-2018 CWR56_RS13275 98e95ac5644e2542bfed92ef03297faf 89 SUPERFAMILY SSF55021 1 83 1.13E-19 T 29-03-2018 CWR56_RS01160 32c11c94d6cd9449c3281df6722e6862 138 Gene3D G3DSA:1.20.58.300 1 121 3.8E-13 T 29-03-2018 CWR56_RS01160 32c11c94d6cd9449c3281df6722e6862 138 SUPERFAMILY SSF140566 1 120 2.62E-11 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CWR56_RS01160 32c11c94d6cd9449c3281df6722e6862 138 Pfam PF05130 FlgN protein 1 136 4.1E-22 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CWR56_RS10770 013f7b00935f8829fe3a46d44b51acef 210 Gene3D G3DSA:2.160.10.10 6 210 4.8E-41 T 29-03-2018 CWR56_RS10770 013f7b00935f8829fe3a46d44b51acef 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 153 2.4E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CWR56_RS10770 013f7b00935f8829fe3a46d44b51acef 210 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 127 155 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR56_RS10770 013f7b00935f8829fe3a46d44b51acef 210 SUPERFAMILY SSF51161 29 209 4.02E-42 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS03670 02933625aaf1112b353578c60de70473 213 Pfam PF00881 Nitroreductase family 14 194 1.5E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS03670 02933625aaf1112b353578c60de70473 213 SUPERFAMILY SSF55469 8 136 3.27E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS03670 02933625aaf1112b353578c60de70473 213 Gene3D G3DSA:3.40.109.10 2 197 7.8E-40 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS15055 8f0737459b872b79bb891883ab154761 310 Pfam PF03595 Voltage-dependent anion channel 34 295 4.1E-24 T 29-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CWR56_RS12650 3a1e1cbcb7e8bacad94b2b69d9d275de 215 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 70 194 9.1E-44 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CWR56_RS12650 3a1e1cbcb7e8bacad94b2b69d9d275de 215 Gene3D G3DSA:3.30.1380.10 48 192 8.2E-39 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS12650 3a1e1cbcb7e8bacad94b2b69d9d275de 215 SUPERFAMILY SSF55166 71 199 9.42E-38 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 SMART SM01008 19 131 2.9E-44 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Gene3D G3DSA:3.30.365.10 266 423 1.6E-39 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 685 2.4E-150 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 19 131 1.8E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Gene3D G3DSA:3.30.365.10 160 265 2.1E-32 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Gene3D G3DSA:3.30.365.10 435 587 6.7E-30 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 SUPERFAMILY SSF56003 123 735 8.64E-174 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Gene3D G3DSA:3.90.1170.50 1 131 3.5E-35 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 SUPERFAMILY SSF54665 4 150 3.27E-42 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CWR56_RS10015 c13cdd69fe0305c9b22724563080ddca 738 Gene3D G3DSA:3.30.365.10 588 738 3.2E-42 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CWR56_RS13355 84132176847dc897d31a76b8e2618c05 253 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 38 250 2.3E-51 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CWR56_RS13355 84132176847dc897d31a76b8e2618c05 253 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 30 247 1.0E-54 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CWR56_RS13355 84132176847dc897d31a76b8e2618c05 253 Gene3D G3DSA:3.60.140.10 17 253 3.1E-59 T 29-03-2018 CWR56_RS13355 84132176847dc897d31a76b8e2618c05 253 SUPERFAMILY SSF64438 31 250 1.41E-57 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CWR56_RS11880 51d46183ec2af38c74f5704fbcc15480 245 SMART SM00650 17 179 7.4E-59 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWR56_RS11880 51d46183ec2af38c74f5704fbcc15480 245 Gene3D G3DSA:3.40.50.150 1 183 9.3E-36 T 29-03-2018 CWR56_RS11880 51d46183ec2af38c74f5704fbcc15480 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWR56_RS11880 51d46183ec2af38c74f5704fbcc15480 245 SUPERFAMILY SSF53335 1 238 7.92E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS11880 51d46183ec2af38c74f5704fbcc15480 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWR56_RS11880 51d46183ec2af38c74f5704fbcc15480 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 2.5E-75 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWR56_RS07615 287809d4cebbbb71d7637afa7a677a76 251 Pfam PF01061 ABC-2 type transporter 6 214 5.2E-29 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CWR56_RS07615 287809d4cebbbb71d7637afa7a677a76 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 5.6E-14 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWR56_RS07615 287809d4cebbbb71d7637afa7a677a76 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 171 190 5.6E-14 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWR56_RS07615 287809d4cebbbb71d7637afa7a677a76 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 134 158 5.6E-14 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWR56_RS07615 287809d4cebbbb71d7637afa7a677a76 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 51 73 5.6E-14 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWR56_RS07615 287809d4cebbbb71d7637afa7a677a76 251 PIRSF PIRSF006648 2 250 2.4E-42 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWR56_RS14225 b3d997255526f06ec48f01e8034cd97d 161 Gene3D G3DSA:1.20.1300.10 3 130 0.0011 T 29-03-2018 CWR56_RS15685 d2aefed01741b09fe781532723ce5d2a 209 Gene3D G3DSA:3.40.50.880 1 208 4.5E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS15685 d2aefed01741b09fe781532723ce5d2a 209 Pfam PF01965 DJ-1/PfpI family 4 176 5.9E-33 T 29-03-2018 IPR002818 DJ-1/PfpI CWR56_RS15685 d2aefed01741b09fe781532723ce5d2a 209 SUPERFAMILY SSF52317 4 178 9.85E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS02440 169a9509e4676d0f3e6335c59b7e1d14 165 SMART SM00871 1 165 3.8E-29 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS02440 169a9509e4676d0f3e6335c59b7e1d14 165 Gene3D G3DSA:3.20.80.10 1 165 4.7E-32 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS02440 169a9509e4676d0f3e6335c59b7e1d14 165 Pfam PF14526 Integron-associated effector binding protein 4 164 1.6E-22 T 29-03-2018 IPR029441 Integron-associated effector binding protein CWR56_RS02440 169a9509e4676d0f3e6335c59b7e1d14 165 SUPERFAMILY SSF55136 1 165 4.19E-19 T 29-03-2018 CWR56_RS15875 b145211d33a30d919fbda7414fac95d7 163 Gene3D G3DSA:3.40.1760.10 1 163 1.9E-42 T 29-03-2018 IPR015068 Protein of unknown function DUF1877 CWR56_RS15875 b145211d33a30d919fbda7414fac95d7 163 SUPERFAMILY SSF111069 3 162 1.7E-30 T 29-03-2018 IPR015068 Protein of unknown function DUF1877 CWR56_RS15875 b145211d33a30d919fbda7414fac95d7 163 Pfam PF08974 Domain of unknown function (DUF1877) 1 161 1.6E-48 T 29-03-2018 IPR015068 Protein of unknown function DUF1877 CWR56_RS15130 ab45ce2a2ac0ece52728d494195e76c0 293 Pfam PF02567 Phenazine biosynthesis-like protein 9 289 3.1E-68 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CWR56_RS15130 ab45ce2a2ac0ece52728d494195e76c0 293 Gene3D G3DSA:3.10.310.10 133 282 1.4E-33 T 29-03-2018 CWR56_RS15130 ab45ce2a2ac0ece52728d494195e76c0 293 Gene3D G3DSA:3.10.310.10 1 132 3.7E-30 T 29-03-2018 CWR56_RS15130 ab45ce2a2ac0ece52728d494195e76c0 293 SUPERFAMILY SSF54506 3 291 1.82E-71 T 29-03-2018 CWR56_RS15130 ab45ce2a2ac0ece52728d494195e76c0 293 PIRSF PIRSF016184 1 293 7.3E-79 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CWR56_RS15130 ab45ce2a2ac0ece52728d494195e76c0 293 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 291 2.3E-78 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 Pfam PF00483 Nucleotidyl transferase 32 167 3.0E-10 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 SUPERFAMILY SSF53448 25 264 8.04E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 SUPERFAMILY SSF53448 325 341 8.04E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 Gene3D G3DSA:3.90.550.10 18 263 2.8E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 3 375 1.6E-122 T 29-03-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 Gene3D G3DSA:2.160.10.10 264 376 1.2E-11 T 29-03-2018 CWR56_RS04340 c71bc12e216a5a36ca34f9a51c09b054 376 SUPERFAMILY SSF51161 286 360 1.12E-13 T 29-03-2018 IPR011004 Trimeric LpxA-like CWR56_RS10635 ab273c0fd9e753172c1e721f24820e57 454 Pfam PF00474 Sodium:solute symporter family 28 414 1.9E-35 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 SUPERFAMILY SSF160467 4 96 1.28E-19 T 29-03-2018 CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 SMART SM00796 3 205 1.6E-94 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 Gene3D G3DSA:3.30.1360.40 1 84 2.2E-20 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 214 2.7E-64 T 29-03-2018 IPR010016 KipI family CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 Gene3D G3DSA:2.40.100.10 89 223 1.6E-50 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 SUPERFAMILY SSF50891 91 221 3.07E-47 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS06475 739ba6c449072d2ca560368f62b7da8b 231 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 204 1.2E-75 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 SUPERFAMILY SSF55890 114 164 5.75E-7 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 110 161 1.4E-11 T 29-03-2018 CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 Gene3D G3DSA:3.30.565.10 161 309 1.5E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 Pfam PF14501 GHKL domain 203 307 1.1E-17 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 Gene3D G3DSA:1.10.287.130 101 160 7.5E-11 T 29-03-2018 CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 SUPERFAMILY SSF55874 171 308 5.24E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS01765 5ac853db98111ea3483f08fdc204f79a 311 SMART SM00387 203 311 4.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS11650 a68ed5453b7937c70f3c84f2d334d89c 452 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 285 435 1.8E-25 T 29-03-2018 IPR006512 YidE/YbjL duplication CWR56_RS11650 a68ed5453b7937c70f3c84f2d334d89c 452 Pfam PF06826 Predicted Permease Membrane Region 7 239 5.7E-18 T 29-03-2018 IPR006512 YidE/YbjL duplication CWR56_RS11650 a68ed5453b7937c70f3c84f2d334d89c 452 Pfam PF06826 Predicted Permease Membrane Region 279 448 1.2E-37 T 29-03-2018 IPR006512 YidE/YbjL duplication CWR56_RS16805 8d617583fdc898389c0a59506e732e14 107 SUPERFAMILY SSF46785 6 103 3.77E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16805 8d617583fdc898389c0a59506e732e14 107 Gene3D G3DSA:1.10.10.10 16 107 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS16805 8d617583fdc898389c0a59506e732e14 107 Pfam PF01638 HxlR-like helix-turn-helix 18 106 5.1E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS12315 81df7413f21e5bf59c38214f175d34fe 133 Gene3D G3DSA:3.40.140.10 2 133 2.1E-45 T 29-03-2018 CWR56_RS12315 81df7413f21e5bf59c38214f175d34fe 133 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 131 2.4E-40 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CWR56_RS12315 81df7413f21e5bf59c38214f175d34fe 133 SUPERFAMILY SSF53927 5 132 5.71E-43 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS12315 81df7413f21e5bf59c38214f175d34fe 133 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 96 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR56_RS12315 81df7413f21e5bf59c38214f175d34fe 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 101 1.0E-15 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR56_RS15180 91ae59f8b3ff31030eae0ae87822e42f 306 SUPERFAMILY SSF53067 115 303 8.64E-47 T 29-03-2018 CWR56_RS15180 91ae59f8b3ff31030eae0ae87822e42f 306 Gene3D G3DSA:3.30.420.40 1 128 1.8E-15 T 29-03-2018 CWR56_RS15180 91ae59f8b3ff31030eae0ae87822e42f 306 SUPERFAMILY SSF53067 1 110 2.81E-19 T 29-03-2018 CWR56_RS15180 91ae59f8b3ff31030eae0ae87822e42f 306 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 299 7.5E-35 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR56_RS15180 91ae59f8b3ff31030eae0ae87822e42f 306 Gene3D G3DSA:3.30.420.40 129 279 4.1E-35 T 29-03-2018 CWR56_RS17425 0467f991e3ed618b27cccf2698fad070 84 Pfam PF07873 YabP family 4 68 3.8E-18 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CWR56_RS17425 0467f991e3ed618b27cccf2698fad070 84 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 5 84 3.0E-10 T 29-03-2018 IPR012504 Sporulation protein YabP CWR56_RS17425 0467f991e3ed618b27cccf2698fad070 84 PIRSF PIRSF011576 1 84 8.7E-16 T 29-03-2018 IPR012504 Sporulation protein YabP CWR56_RS03975 240896e215fc89559550cf4a4d560d63 100 SUPERFAMILY SSF52794 15 96 3.92E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS03975 240896e215fc89559550cf4a4d560d63 100 Gene3D G3DSA:3.40.50.2300 4 98 9.1E-12 T 29-03-2018 CWR56_RS10765 4a495877912615dd0a03393bd0d935b8 117 SUPERFAMILY SSF54171 4 74 8.5E-36 T 29-03-2018 IPR016177 DNA-binding domain GO:0003677 CWR56_RS10765 4a495877912615dd0a03393bd0d935b8 117 Gene3D G3DSA:3.30.160.60 6 71 1.5E-25 T 29-03-2018 CWR56_RS10765 4a495877912615dd0a03393bd0d935b8 117 Pfam PF02920 DNA binding domain of tn916 integrase 3 72 1.7E-26 T 29-03-2018 IPR004191 Integrase, Tn916-type, N-terminal DNA binding GO:0003677|GO:0008907|GO:0015074 CWR56_RS05005 7f6990253616b598b5d662e9a22c37db 177 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 157 2.4E-45 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CWR56_RS05005 7f6990253616b598b5d662e9a22c37db 177 SUPERFAMILY SSF52540 4 156 2.17E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS05005 7f6990253616b598b5d662e9a22c37db 177 Gene3D G3DSA:3.40.50.300 2 164 8.3E-28 T 29-03-2018 CWR56_RS05005 7f6990253616b598b5d662e9a22c37db 177 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 133 2.6E-43 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CWR56_RS02260 10befe1db877607c42138a4c2e6cf600 226 Gene3D G3DSA:3.30.470.20 101 218 2.0E-27 T 29-03-2018 CWR56_RS02260 10befe1db877607c42138a4c2e6cf600 226 Gene3D G3DSA:3.30.200.20 1 100 1.9E-17 T 29-03-2018 CWR56_RS02260 10befe1db877607c42138a4c2e6cf600 226 SUPERFAMILY SSF56104 1 209 7.85E-48 T 29-03-2018 CWR56_RS02260 10befe1db877607c42138a4c2e6cf600 226 Pfam PF01259 SAICAR synthetase 3 209 1.2E-28 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR56_RS03015 faa507ee93d9f5d9b61565d68e83eaec 162 Pfam PF12952 Domain of unknown function (DUF3841) 3 102 6.9E-13 T 29-03-2018 IPR024211 Protein of unknown function DUF3841 CWR56_RS14575 686232ecbac8ce388ce608f99e98971b 404 Gene3D G3DSA:3.50.50.60 15 242 2.4E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS14575 686232ecbac8ce388ce608f99e98971b 404 Gene3D G3DSA:3.30.9.10 243 345 1.1E-7 T 29-03-2018 CWR56_RS14575 686232ecbac8ce388ce608f99e98971b 404 Pfam PF01266 FAD dependent oxidoreductase 32 385 8.2E-50 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CWR56_RS14575 686232ecbac8ce388ce608f99e98971b 404 SUPERFAMILY SSF51905 30 304 1.43E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS17265 9d0b1d5fe4ea791920f144ef6ac0bd32 196 Gene3D G3DSA:2.50.20.10 30 196 1.2E-13 T 29-03-2018 CWR56_RS17265 9d0b1d5fe4ea791920f144ef6ac0bd32 196 SUPERFAMILY SSF89392 68 192 7.06E-5 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CWR56_RS18160 fa8161c8e52463a14da30c9a76340a7e 170 Pfam PF06496 Protein of unknown function (DUF1097) 13 157 5.0E-26 T 29-03-2018 IPR009476 Protein of unknown function DUF1097 CWR56_RS12980 34787dc0191213c4bb52fa840a55a0e3 102 Gene3D G3DSA:3.40.50.2300 2 101 2.5E-35 T 29-03-2018 CWR56_RS12980 34787dc0191213c4bb52fa840a55a0e3 102 SUPERFAMILY SSF52794 2 99 2.27E-33 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS12980 34787dc0191213c4bb52fa840a55a0e3 102 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 88 3.6E-27 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS12980 34787dc0191213c4bb52fa840a55a0e3 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 2.5E-15 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS08905 bfeef04fac169a4994c6822028b884f1 115 Gene3D G3DSA:2.60.120.10 2 110 5.4E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS08905 bfeef04fac169a4994c6822028b884f1 115 SUPERFAMILY SSF51182 27 104 2.88E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS08905 bfeef04fac169a4994c6822028b884f1 115 Pfam PF07883 Cupin domain 38 102 4.8E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS03530 9bce9f66277695116201d9e046147a06 125 Pfam PF01597 Glycine cleavage H-protein 7 123 7.0E-42 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CWR56_RS03530 9bce9f66277695116201d9e046147a06 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 34.841 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CWR56_RS03530 9bce9f66277695116201d9e046147a06 125 SUPERFAMILY SSF51230 4 123 1.92E-38 T 29-03-2018 IPR011053 Single hybrid motif CWR56_RS03530 9bce9f66277695116201d9e046147a06 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 124 2.5E-41 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CWR56_RS03530 9bce9f66277695116201d9e046147a06 125 Gene3D G3DSA:2.40.50.100 5 125 5.4E-42 T 29-03-2018 CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 Pfam PF00149 Calcineurin-like phosphoesterase 29 275 4.3E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 SUPERFAMILY SSF56300 23 340 1.37E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 Gene3D G3DSA:3.60.21.10 19 354 6.4E-56 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 PRINTS PR01607 Apyrase family signature 290 310 2.1E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 PRINTS PR01607 Apyrase family signature 230 247 2.1E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 PRINTS PR01607 Apyrase family signature 258 281 2.1E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS00995 a6b0ae713cf74f4cbd08ba2811afdca7 463 PRINTS PR01607 Apyrase family signature 26 44 2.1E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR56_RS04140 530edff26e3a0b5eb13886bab3138a6c 119 Gene3D G3DSA:3.40.50.1580 1 110 8.5E-11 T 29-03-2018 CWR56_RS04140 530edff26e3a0b5eb13886bab3138a6c 119 SUPERFAMILY SSF53167 1 98 2.36E-13 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR56_RS04140 530edff26e3a0b5eb13886bab3138a6c 119 Pfam PF01048 Phosphorylase superfamily 1 93 3.8E-9 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR56_RS12740 e238036e6d8f1c8eadfab3c1109097ea 222 Pfam PF04892 VanZ like family 85 184 3.1E-23 T 29-03-2018 IPR006976 VanZ-like CWR56_RS10215 0b1846ff44ced1472ead15a509082526 308 Pfam PF03547 Membrane transport protein 160 302 4.3E-17 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CWR56_RS10215 0b1846ff44ced1472ead15a509082526 308 Pfam PF03547 Membrane transport protein 6 150 2.3E-15 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CWR56_RS04240 4f2bd6acc582a25a40f65b3f25ec079e 109 SUPERFAMILY SSF46973 2 100 5.49E-25 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS04240 4f2bd6acc582a25a40f65b3f25ec079e 109 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 100 5.2E-24 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS04240 4f2bd6acc582a25a40f65b3f25ec079e 109 Gene3D G3DSA:1.20.58.80 3 101 2.1E-25 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR56_RS17495 6e33610724e24ae62e8123447d68f2d6 189 Gene3D G3DSA:3.30.700.10 13 186 8.1E-4 T 29-03-2018 CWR56_RS17495 6e33610724e24ae62e8123447d68f2d6 189 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17495 6e33610724e24ae62e8123447d68f2d6 189 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 32 1.6E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS17495 6e33610724e24ae62e8123447d68f2d6 189 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 30 4.6E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR56_RS16165 202c6962b80f59967a37e8bf9fecd7b5 266 SUPERFAMILY SSF102588 51 208 7.19E-10 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR56_RS16165 202c6962b80f59967a37e8bf9fecd7b5 266 Gene3D G3DSA:3.40.50.10320 33 246 5.9E-13 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR56_RS16165 202c6962b80f59967a37e8bf9fecd7b5 266 Pfam PF02585 GlcNAc-PI de-N-acetylase 51 173 6.0E-8 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CWR56_RS08240 0e5982da838359c36331820c639bb7af 94 Gene3D G3DSA:1.10.1220.10 1 55 4.0E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWR56_RS12415 e13984a53b3beda02498a886ca0bf0b5 255 Pfam PF13556 PucR C-terminal helix-turn-helix domain 197 247 1.9E-16 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CWR56_RS12415 e13984a53b3beda02498a886ca0bf0b5 255 Gene3D G3DSA:1.10.10.60 147 226 4.1E-5 T 29-03-2018 CWR56_RS01040 6c2a1dde0c04e9cc5fe8516d89774175 102 SUPERFAMILY SSF52794 2 99 2.09E-35 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS01040 6c2a1dde0c04e9cc5fe8516d89774175 102 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 88 1.0E-33 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR56_RS01040 6c2a1dde0c04e9cc5fe8516d89774175 102 Gene3D G3DSA:3.40.50.2300 2 100 1.2E-39 T 29-03-2018 CWR56_RS01040 6c2a1dde0c04e9cc5fe8516d89774175 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 1.9E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS01660 39dd82b3cca25942d742ecb0e2df413f 307 SMART SM00382 30 213 1.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS01660 39dd82b3cca25942d742ecb0e2df413f 307 Pfam PF00005 ABC transporter 22 162 2.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS01660 39dd82b3cca25942d742ecb0e2df413f 307 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS01660 39dd82b3cca25942d742ecb0e2df413f 307 SUPERFAMILY SSF52540 3 235 1.16E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS01660 39dd82b3cca25942d742ecb0e2df413f 307 Gene3D G3DSA:3.40.50.300 2 258 2.8E-57 T 29-03-2018 CWR56_RS07625 c89e74573bf48d7e2265ad775e01bc72 152 SUPERFAMILY SSF55136 4 150 4.81E-17 T 29-03-2018 CWR56_RS07625 c89e74573bf48d7e2265ad775e01bc72 152 Gene3D G3DSA:3.20.80.10 3 150 1.8E-27 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS07625 c89e74573bf48d7e2265ad775e01bc72 152 Pfam PF06445 GyrI-like small molecule binding domain 4 149 2.1E-12 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS07625 c89e74573bf48d7e2265ad775e01bc72 152 SMART SM00871 3 149 1.0E-20 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR56_RS15815 611dd8b29413bdff72da77743e90faf9 250 SUPERFAMILY SSF140931 69 237 3.66E-21 T 29-03-2018 IPR003812 Fido domain CWR56_RS15815 611dd8b29413bdff72da77743e90faf9 250 Gene3D G3DSA:1.10.3290.10 13 241 2.2E-35 T 29-03-2018 IPR003812 Fido domain CWR56_RS15815 611dd8b29413bdff72da77743e90faf9 250 Pfam PF02661 Fic/DOC family 94 188 2.9E-9 T 29-03-2018 IPR003812 Fido domain CWR56_RS04030 5ac90158e78bf4f85565b745aae14701 253 Pfam PF12730 ABC-2 family transporter protein 4 175 3.0E-40 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS05175 2914cf040456c336475a7ac740777039 191 PIRSF PIRSF006102 1 191 5.5E-60 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CWR56_RS05175 2914cf040456c336475a7ac740777039 191 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 189 5.9E-63 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CWR56_RS05175 2914cf040456c336475a7ac740777039 191 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 1 189 7.6E-82 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 CWR56_RS05175 2914cf040456c336475a7ac740777039 191 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 1 189 25.918 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 CWR56_RS17885 361e04a9209e4adc3d7e90acd0f3699f 290 SUPERFAMILY SSF53335 3 251 1.1E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS17885 361e04a9209e4adc3d7e90acd0f3699f 290 Gene3D G3DSA:2.60.40.1180 10 59 5.5E-27 T 29-03-2018 CWR56_RS17885 361e04a9209e4adc3d7e90acd0f3699f 290 Gene3D G3DSA:3.40.50.150 60 272 1.9E-38 T 29-03-2018 CWR56_RS17885 361e04a9209e4adc3d7e90acd0f3699f 290 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 70 202 2.0E-18 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CWR56_RS16800 a1b6739d6ed69f0e1c90b0981adb8c8a 172 Gene3D G3DSA:3.40.109.10 2 172 2.5E-39 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS16800 a1b6739d6ed69f0e1c90b0981adb8c8a 172 Pfam PF00881 Nitroreductase family 8 64 1.1E-15 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR56_RS16800 a1b6739d6ed69f0e1c90b0981adb8c8a 172 SUPERFAMILY SSF55469 1 170 1.19E-45 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR56_RS10625 1f34a1ca7db373b19158757971c9ff85 367 Gene3D G3DSA:3.40.640.10 47 253 1.7E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS10625 1f34a1ca7db373b19158757971c9ff85 367 Gene3D G3DSA:3.90.1150.10 254 358 7.9E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS10625 1f34a1ca7db373b19158757971c9ff85 367 SUPERFAMILY SSF53383 10 358 2.75E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS10625 1f34a1ca7db373b19158757971c9ff85 367 Pfam PF00155 Aminotransferase class I and II 33 352 1.1E-53 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS10625 1f34a1ca7db373b19158757971c9ff85 367 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 357 4.1E-102 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CWR56_RS10625 1f34a1ca7db373b19158757971c9ff85 367 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 358 55.103 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CWR56_RS09345 b676ee096f923bb519c454437650b250 805 Pfam PF02687 FtsX-like permease family 703 796 2.2E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 Gene3D G3DSA:3.30.565.10 181 329 2.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 257 271 6.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 275 285 6.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 310 6.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 221 327 3.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 SMART SM00387 220 332 4.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 Gene3D G3DSA:1.10.287.130 109 172 0.0028 T 29-03-2018 CWR56_RS15220 a29790f9eb8f4276073e71ab103d7667 339 SUPERFAMILY SSF55874 185 328 2.88E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS08495 a1c01e90fe78b30a883ca62b7d0da9f1 154 Pfam PF15417 Domain of unknown function (DUF4624) 22 153 2.3E-80 T 29-03-2018 IPR028113 Protein of unknown function DUF4624 CWR56_RS03765 a577e855d34d587d8d542ddcf78c788d 120 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 5 117 1.1E-39 T 29-03-2018 IPR014204 Sporulation stage V, protein AE CWR56_RS03765 a577e855d34d587d8d542ddcf78c788d 120 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 5 113 4.2E-33 T 29-03-2018 IPR005562 SpoVA CWR56_RS02415 7c7aaa98a96785538624056a3a8549bc 248 SMART SM00849 8 214 8.4E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02415 7c7aaa98a96785538624056a3a8549bc 248 Pfam PF00753 Metallo-beta-lactamase superfamily 6 214 4.5E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02415 7c7aaa98a96785538624056a3a8549bc 248 Gene3D G3DSA:3.60.15.10 3 219 3.5E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02415 7c7aaa98a96785538624056a3a8549bc 248 SUPERFAMILY SSF56281 4 220 5.63E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS11725 b1fdd3afa0edfd96f8bd24c894fc4102 161 Pfam PF03243 Alkylmercury lyase 79 154 1.9E-16 T 29-03-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 CWR56_RS11725 b1fdd3afa0edfd96f8bd24c894fc4102 161 SUPERFAMILY SSF160387 83 161 2.28E-20 T 29-03-2018 CWR56_RS05880 221bc624f4eaca95b62ef887e9ef15ae 387 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 293 339 3.7E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS05880 221bc624f4eaca95b62ef887e9ef15ae 387 SUPERFAMILY SSF55874 271 378 8.25E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS05880 221bc624f4eaca95b62ef887e9ef15ae 387 Gene3D G3DSA:3.30.565.10 160 379 3.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS05880 221bc624f4eaca95b62ef887e9ef15ae 387 Pfam PF07730 Histidine kinase 188 252 9.3E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWR56_RS17945 026f26a69dccd85b654fc82497731bbb 195 Pfam PF08901 Protein of unknown function (DUF1847) 8 163 3.4E-65 T 29-03-2018 IPR014997 Protein of unknown function DUF1847 CWR56_RS13385 250627b4fc38a285efad022c8a8cff38 424 Gene3D G3DSA:3.40.190.10 29 161 3.9E-23 T 29-03-2018 CWR56_RS13385 250627b4fc38a285efad022c8a8cff38 424 Pfam PF13416 Bacterial extracellular solute-binding protein 58 357 1.5E-43 T 29-03-2018 CWR56_RS13385 250627b4fc38a285efad022c8a8cff38 424 SUPERFAMILY SSF53850 22 422 3.21E-83 T 29-03-2018 CWR56_RS13385 250627b4fc38a285efad022c8a8cff38 424 Gene3D G3DSA:3.40.190.10 162 423 2.0E-44 T 29-03-2018 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 SUPERFAMILY SSF54862 2 61 2.42E-14 T 29-03-2018 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 Gene3D G3DSA:3.30.70.20 1 16 7.1E-4 T 29-03-2018 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 Gene3D G3DSA:3.30.70.20 17 62 1.5E-7 T 29-03-2018 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 1.8E-17 T 29-03-2018 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR56_RS18010 4a007cf7cc3bcf42a3222c8941ace096 62 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR56_RS03855 b16903c24ca1b5ce9db71d444e89b539 225 Gene3D G3DSA:1.25.40.70 150 220 2.0E-5 T 29-03-2018 CWR56_RS03855 b16903c24ca1b5ce9db71d444e89b539 225 Gene3D G3DSA:1.25.40.70 24 149 0.019 T 29-03-2018 CWR56_RS03855 b16903c24ca1b5ce9db71d444e89b539 225 SUPERFAMILY SSF48371 100 208 4.94E-14 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWR56_RS03855 b16903c24ca1b5ce9db71d444e89b539 225 Pfam PF13646 HEAT repeats 127 201 2.9E-9 T 29-03-2018 CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 PIRSF PIRSF004862 5 516 2.0E-98 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 Pfam PF08345 Flagellar M-ring protein C-terminal 265 407 1.3E-29 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 15 516 1.6E-61 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 Pfam PF01514 Secretory protein of YscJ/FliF family 35 221 2.2E-54 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 PRINTS PR01009 Flagellar M-ring protein signature 122 140 1.0E-16 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 PRINTS PR01009 Flagellar M-ring protein signature 154 168 1.0E-16 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 PRINTS PR01009 Flagellar M-ring protein signature 197 215 1.0E-16 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CWR56_RS01265 a4506ddb51a4061daa34dd9b4733ca5a 516 PRINTS PR01009 Flagellar M-ring protein signature 344 368 1.0E-16 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CWR56_RS15940 a2b1b5f718d993f2524cfbb0b4a5acc5 340 Pfam PF04198 Putative sugar-binding domain 91 337 3.4E-55 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CWR56_RS15940 a2b1b5f718d993f2524cfbb0b4a5acc5 340 Gene3D G3DSA:3.40.50.1360 95 340 4.8E-31 T 29-03-2018 CWR56_RS15940 a2b1b5f718d993f2524cfbb0b4a5acc5 340 Gene3D G3DSA:1.10.10.10 17 87 1.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15940 a2b1b5f718d993f2524cfbb0b4a5acc5 340 SUPERFAMILY SSF46785 18 85 7.37E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS15940 a2b1b5f718d993f2524cfbb0b4a5acc5 340 SUPERFAMILY SSF100950 90 337 2.65E-59 T 29-03-2018 CWR56_RS07675 439e2dc438bda5243821041d6745ebeb 686 Pfam PF12698 ABC-2 family transporter protein 21 393 6.2E-28 T 29-03-2018 CWR56_RS07675 439e2dc438bda5243821041d6745ebeb 686 Pfam PF02517 CAAX protease self-immunity 540 629 1.2E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR56_RS07450 71ccb650066b92a20b84b5da085377cb 404 Gene3D G3DSA:1.25.40.10 114 372 2.4E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS07450 71ccb650066b92a20b84b5da085377cb 404 SUPERFAMILY SSF48452 117 226 7.91E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS07450 71ccb650066b92a20b84b5da085377cb 404 SMART SM00530 8 63 9.2E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07450 71ccb650066b92a20b84b5da085377cb 404 Pfam PF01381 Helix-turn-helix 12 63 1.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR56_RS07450 71ccb650066b92a20b84b5da085377cb 404 SUPERFAMILY SSF47413 3 67 7.84E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR56_RS07450 71ccb650066b92a20b84b5da085377cb 404 Gene3D G3DSA:1.10.260.40 1 113 6.2E-23 T 29-03-2018 CWR56_RS07260 105c8d24ac292d410dc528847d0dd159 645 Pfam PF02687 FtsX-like permease family 82 176 3.8E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS07260 105c8d24ac292d410dc528847d0dd159 645 PIRSF PIRSF018968 1 645 7.2E-109 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR56_RS03610 4b89529a8f30766ca8236e134f003707 262 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 218 2.9E-26 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CWR56_RS05845 09ef0feea7bd4848f2713faf2f97c75d 338 Gene3D G3DSA:3.20.20.70 35 337 4.8E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS05845 09ef0feea7bd4848f2713faf2f97c75d 338 SUPERFAMILY SSF51395 38 336 6.68E-63 T 29-03-2018 CWR56_RS05845 09ef0feea7bd4848f2713faf2f97c75d 338 PIRSF PIRSF000138 2 197 7.1E-22 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CWR56_RS05845 09ef0feea7bd4848f2713faf2f97c75d 338 PIRSF PIRSF000138 192 338 6.0E-60 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CWR56_RS05845 09ef0feea7bd4848f2713faf2f97c75d 338 Pfam PF01070 FMN-dependent dehydrogenase 194 336 1.4E-56 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CWR56_RS05845 09ef0feea7bd4848f2713faf2f97c75d 338 Pfam PF01070 FMN-dependent dehydrogenase 37 178 7.3E-14 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CWR56_RS13365 36a7fefa1e2543bdccdea04526dd2d22 87 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 75 2.1E-18 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CWR56_RS13365 36a7fefa1e2543bdccdea04526dd2d22 87 Gene3D G3DSA:2.30.30.240 1 79 2.2E-13 T 29-03-2018 CWR56_RS13365 36a7fefa1e2543bdccdea04526dd2d22 87 Pfam PF05239 PRC-barrel domain 1 79 1.1E-7 T 29-03-2018 IPR027275 PRC-barrel domain CWR56_RS13365 36a7fefa1e2543bdccdea04526dd2d22 87 SUPERFAMILY SSF50346 1 75 5.89E-11 T 29-03-2018 IPR011033 PRC-barrel-like CWR56_RS08365 7d4e6a8e9c552f5b42e2793f6a1c3806 144 Gene3D G3DSA:1.20.120.330 7 128 1.5E-5 T 29-03-2018 CWR56_RS02400 e11b2b0b08e84303e4461f672ad4a736 428 Gene3D G3DSA:1.10.10.10 349 419 2.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS01250 e7df64955f59f3cec4e168d43882b02f 105 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 10 30 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CWR56_RS01250 e7df64955f59f3cec4e168d43882b02f 105 PIRSF PIRSF002889 1 53 4.6E-15 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CWR56_RS01250 e7df64955f59f3cec4e168d43882b02f 105 PIRSF PIRSF002889 46 105 2.0E-13 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CWR56_RS01250 e7df64955f59f3cec4e168d43882b02f 105 Pfam PF00460 Flagella basal body rod protein 10 34 3.1E-7 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CWR56_RS05440 e069a05121832f1b3aa0edaf4f2baf05 173 PIRSF PIRSF021435 2 173 2.8E-25 T 29-03-2018 IPR014198 Stage III sporulation protein AB CWR56_RS05440 e069a05121832f1b3aa0edaf4f2baf05 173 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 4 173 9.0E-37 T 29-03-2018 IPR014198 Stage III sporulation protein AB CWR56_RS15515 9ae59eed57ddbc0c64a80ea10a66ce09 213 SUPERFAMILY SSF51569 1 211 1.47E-52 T 29-03-2018 CWR56_RS15515 9ae59eed57ddbc0c64a80ea10a66ce09 213 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 197 2.4E-30 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR56_RS15515 9ae59eed57ddbc0c64a80ea10a66ce09 213 Gene3D G3DSA:3.20.20.70 1 213 1.4E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS04710 a6dda3dc644d99a082198a767c97714b 361 Gene3D G3DSA:3.20.20.80 40 356 1.6E-19 T 29-03-2018 CWR56_RS04710 a6dda3dc644d99a082198a767c97714b 361 SUPERFAMILY SSF51445 20 356 2.62E-22 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS10065 7434cc3296be3817ebebf6e6c5d7d8e1 166 Pfam PF06177 QueT transporter 8 156 3.0E-41 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CWR56_RS10065 7434cc3296be3817ebebf6e6c5d7d8e1 166 PIRSF PIRSF031501 1 164 3.0E-41 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CWR56_RS01895 1b44a16ab50f5bb38d4193725255eb10 408 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 37 396 2.0E-72 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit CWR56_RS16530 888445443416e54803512fe66ca0df0b 534 SUPERFAMILY SSF51905 98 291 6.85E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS16530 888445443416e54803512fe66ca0df0b 534 SUPERFAMILY SSF51905 465 526 6.85E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS16530 888445443416e54803512fe66ca0df0b 534 PIRSF PIRSF038984 1 532 5.8E-248 T 29-03-2018 IPR028348 FAD dependent protein CWR56_RS16530 888445443416e54803512fe66ca0df0b 534 Gene3D G3DSA:3.50.50.60 93 528 2.7E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR56_RS08050 675b2fad6dbdb63771bb2144a46e03de 229 Gene3D G3DSA:3.80.30.20 22 191 1.6E-6 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR56_RS08050 675b2fad6dbdb63771bb2144a46e03de 229 SMART SM00729 13 221 0.0025 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR56_RS13340 4af03fd1a292aca76f3722c2bceef2d1 310 Pfam PF14045 YIEGIA protein 15 304 1.9E-105 T 29-03-2018 IPR025918 YIEGIA protein CWR56_RS13340 4af03fd1a292aca76f3722c2bceef2d1 310 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 16 304 1.0E-56 T 29-03-2018 CWR56_RS17105 4ef46d71bcdbc38607854f2ed6f67771 323 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 317 90.554 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CWR56_RS17105 4ef46d71bcdbc38607854f2ed6f67771 323 Pfam PF03186 CobD/Cbib protein 7 296 3.1E-100 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CWR56_RS17105 4ef46d71bcdbc38607854f2ed6f67771 323 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 10 318 3.4E-75 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 Pfam PF04122 Putative cell wall binding repeat 2 374 454 6.6E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 Pfam PF04122 Putative cell wall binding repeat 2 269 358 7.3E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 Pfam PF04122 Putative cell wall binding repeat 2 169 254 4.9E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 SMART SM00646 547 668 6.8E-22 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 Gene3D G3DSA:3.40.630.40 481 672 1.1E-51 T 29-03-2018 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 SUPERFAMILY SSF53187 484 671 1.7E-49 T 29-03-2018 CWR56_RS04745 6b660ffb49127f7a2d5c1050efd9d995 672 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 486 668 2.5E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS09180 90abae7b646cce7c7e665b0f94cec091 385 SUPERFAMILY SSF56281 55 296 1.49E-49 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS09180 90abae7b646cce7c7e665b0f94cec091 385 Pfam PF00753 Metallo-beta-lactamase superfamily 66 255 8.0E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS09180 90abae7b646cce7c7e665b0f94cec091 385 Gene3D G3DSA:3.60.15.10 32 279 1.6E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS09180 90abae7b646cce7c7e665b0f94cec091 385 SMART SM00849 67 256 6.3E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS02280 27334d77f53286062f84ac81bd7cf304 252 Pfam PF03609 PTS system sorbose-specific iic component 5 238 4.3E-72 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWR56_RS06705 753339c89ff7a1dda4feb48555c6abf7 121 Gene3D G3DSA:1.10.10.10 15 113 5.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06705 753339c89ff7a1dda4feb48555c6abf7 121 Pfam PF01638 HxlR-like helix-turn-helix 17 104 4.3E-21 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR56_RS06705 753339c89ff7a1dda4feb48555c6abf7 121 SUPERFAMILY SSF46785 6 111 5.81E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03000 a3df3b4ff34eb43d00ad766e203c5fe9 147 Gene3D G3DSA:3.40.630.30 2 147 3.9E-18 T 29-03-2018 CWR56_RS03000 a3df3b4ff34eb43d00ad766e203c5fe9 147 SUPERFAMILY SSF55729 16 145 3.24E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR56_RS03000 a3df3b4ff34eb43d00ad766e203c5fe9 147 Pfam PF13508 Acetyltransferase (GNAT) domain 34 113 1.2E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 PIRSF PIRSF034834 1 183 1.1E-58 T 29-03-2018 IPR011238 Polyhedral organelle shell protein PduT CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 97 152 1.0E-5 T 29-03-2018 CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 60 1.0E-15 T 29-03-2018 CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 SUPERFAMILY SSF143414 3 89 1.7E-17 T 29-03-2018 CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 Pfam PF00936 BMC domain 97 172 2.0E-11 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 Pfam PF00936 BMC domain 4 75 1.6E-16 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 SMART SM00877 3 77 5.6E-16 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 SMART SM00877 96 173 6.8E-9 T 29-03-2018 IPR000249 Microcompartment protein, bacteria CWR56_RS09130 96ee8940dfe506b148bd598d1e384e98 183 SUPERFAMILY SSF143414 97 181 2.75E-12 T 29-03-2018 CWR56_RS02665 521e0a3405d51cd4e3e9cccb57d9ab21 189 Gene3D G3DSA:1.10.3210.10 8 183 4.7E-7 T 29-03-2018 CWR56_RS02665 521e0a3405d51cd4e3e9cccb57d9ab21 189 SUPERFAMILY SSF109604 1 127 2.48E-12 T 29-03-2018 CWR56_RS18155 669cfcd4a9aebb8011cd504db57e962e 284 Gene3D G3DSA:3.30.70.100 163 251 1.9E-4 T 29-03-2018 CWR56_RS14845 14ed57372e426138425323980e6e2898 638 PIRSF PIRSF018968 1 635 4.0E-124 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR56_RS14845 14ed57372e426138425323980e6e2898 638 Pfam PF02687 FtsX-like permease family 85 174 1.9E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS07055 9836665ca7195034f27fef634fc1ea3b 158 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 4 108 8.5E-8 T 29-03-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain CWR56_RS16455 e75ff41fc9c337c5d95ed63cfadd84d8 169 PIRSF PIRSF027391 1 168 2.1E-45 T 29-03-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I CWR56_RS16455 e75ff41fc9c337c5d95ed63cfadd84d8 169 Pfam PF07456 Heptaprenyl diphosphate synthase component I 12 156 2.3E-44 T 29-03-2018 IPR010898 Heptaprenyl diphosphate synthase component I CWR56_RS16480 1381917af51efdff405335f9272e3159 263 Pfam PF03609 PTS system sorbose-specific iic component 2 234 1.6E-74 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWR56_RS02645 6eaf52ff2d47ff6029179812e6b25a70 200 Pfam PF04286 Protein of unknown function (DUF445) 12 137 1.6E-18 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CWR56_RS02645 6eaf52ff2d47ff6029179812e6b25a70 200 Pfam PF04286 Protein of unknown function (DUF445) 78 200 2.0E-17 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CWR56_RS10610 8f5ab40c6a5dcde4f695b2e36a197112 246 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 208 6.5E-21 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR56_RS10610 8f5ab40c6a5dcde4f695b2e36a197112 246 Gene3D G3DSA:3.40.50.970 74 246 1.0E-32 T 29-03-2018 CWR56_RS10610 8f5ab40c6a5dcde4f695b2e36a197112 246 Gene3D G3DSA:3.40.50.970 2 73 3.8E-9 T 29-03-2018 CWR56_RS10610 8f5ab40c6a5dcde4f695b2e36a197112 246 SUPERFAMILY SSF52518 13 236 3.42E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR56_RS04365 c353c3e93eb30eef3cdbf30b6b925d3d 491 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 405 473 2.4E-9 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR56_RS04365 c353c3e93eb30eef3cdbf30b6b925d3d 491 Gene3D G3DSA:3.40.640.10 16 293 4.2E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS04365 c353c3e93eb30eef3cdbf30b6b925d3d 491 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 17 379 1.7E-71 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CWR56_RS04365 c353c3e93eb30eef3cdbf30b6b925d3d 491 SUPERFAMILY SSF53383 17 396 3.02E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS04365 c353c3e93eb30eef3cdbf30b6b925d3d 491 Gene3D G3DSA:3.90.100.10 381 491 4.9E-28 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR56_RS00250 b03a857e4752d840f361fd094ea781bf 267 Pfam PF02361 Cobalt transport protein 14 235 1.3E-54 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWR56_RS00250 b03a857e4752d840f361fd094ea781bf 267 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 264 34.321 T 29-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CWR56_RS11200 f7ebecbc75446269c175cf98e27fc234 115 SUPERFAMILY SSF51182 29 111 8.91E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain CWR56_RS11200 f7ebecbc75446269c175cf98e27fc234 115 Gene3D G3DSA:2.60.120.10 1 115 1.6E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CWR56_RS11200 f7ebecbc75446269c175cf98e27fc234 115 Pfam PF07883 Cupin domain 44 110 2.1E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CWR56_RS08470 a4cf195504227bbb3072bca08ed25cd5 139 PIRSF PIRSF021328 3 139 3.4E-45 T 29-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CWR56_RS08470 a4cf195504227bbb3072bca08ed25cd5 139 Pfam PF11208 Protein of unknown function (DUF2992) 8 139 1.1E-49 T 29-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CWR56_RS17090 281a75acb616a2f08709624f0e62f55b 210 Gene3D G3DSA:3.40.50.10230 3 210 3.8E-77 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CWR56_RS17090 281a75acb616a2f08709624f0e62f55b 210 SUPERFAMILY SSF63965 9 209 4.19E-67 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CWR56_RS17090 281a75acb616a2f08709624f0e62f55b 210 Pfam PF02570 Precorrin-8X methylmutase 9 208 9.8E-72 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CWR56_RS09695 f46248911dc4a4607bf221266dab244b 205 Pfam PF12870 Domain of unknown function (DUF4878) 19 108 2.0E-8 T 29-03-2018 IPR024267 Domain of unknown function (DUF4878) CWR56_RS09695 f46248911dc4a4607bf221266dab244b 205 Gene3D G3DSA:3.40.190.10 1 202 5.0E-5 T 29-03-2018 CWR56_RS16795 2d1588dcc7c7c6d49d4e887184313db4 222 SMART SM00873 60 212 2.7E-4 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS16795 2d1588dcc7c7c6d49d4e887184313db4 222 SUPERFAMILY SSF56037 66 207 6.02E-11 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS16795 2d1588dcc7c7c6d49d4e887184313db4 222 Pfam PF03483 B3/4 domain 114 192 1.5E-7 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR56_RS16795 2d1588dcc7c7c6d49d4e887184313db4 222 Gene3D G3DSA:3.50.40.10 47 204 5.9E-13 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR56_RS12380 af272093e185e2bae0343962d57e4bc4 315 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 306 9.7E-81 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWR56_RS12380 af272093e185e2bae0343962d57e4bc4 315 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 4 313 35.447 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWR56_RS12380 af272093e185e2bae0343962d57e4bc4 315 PIRSF PIRSF000401 2 315 4.0E-106 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWR56_RS12380 af272093e185e2bae0343962d57e4bc4 315 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 312 6.3E-101 T 29-03-2018 CWR56_RS12380 af272093e185e2bae0343962d57e4bc4 315 SUPERFAMILY SSF53335 98 309 7.17E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS12380 af272093e185e2bae0343962d57e4bc4 315 Gene3D G3DSA:3.40.50.150 119 315 2.1E-42 T 29-03-2018 CWR56_RS12340 0f28e788ba0d23e695232f82e000da20 80 Pfam PF07873 YabP family 15 78 1.2E-14 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CWR56_RS17170 0a00ab81ff0e2ea536aad6990dd65bb8 111 SUPERFAMILY SSF52794 1 104 2.38E-24 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS17170 0a00ab81ff0e2ea536aad6990dd65bb8 111 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 97 1.1E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS17170 0a00ab81ff0e2ea536aad6990dd65bb8 111 Gene3D G3DSA:3.40.50.2300 1 111 1.3E-34 T 29-03-2018 CWR56_RS07660 f638f0ce0a4079f37bb56d98fd6e425d 393 Gene3D G3DSA:2.30.40.10 3 71 1.0E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07660 f638f0ce0a4079f37bb56d98fd6e425d 393 SUPERFAMILY SSF51556 58 351 1.02E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase CWR56_RS07660 f638f0ce0a4079f37bb56d98fd6e425d 393 SUPERFAMILY SSF51338 1 70 9.87E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR56_RS07660 f638f0ce0a4079f37bb56d98fd6e425d 393 Pfam PF01979 Amidohydrolase family 54 392 9.6E-41 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR56_RS07660 f638f0ce0a4079f37bb56d98fd6e425d 393 Gene3D G3DSA:3.20.20.140 72 351 4.6E-44 T 29-03-2018 CWR56_RS11935 e277f615659df44b05386fe97c2390c8 167 Pfam PF07275 Antirestriction protein (ArdA) 20 163 2.8E-9 T 29-03-2018 IPR009899 Antirestriction CWR56_RS06220 5b51083a1f0e21e07522ebebecaa80af 398 Pfam PF00155 Aminotransferase class I and II 55 383 4.8E-49 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR56_RS06220 5b51083a1f0e21e07522ebebecaa80af 398 SUPERFAMILY SSF53383 1 392 9.55E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS06220 5b51083a1f0e21e07522ebebecaa80af 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWR56_RS06220 5b51083a1f0e21e07522ebebecaa80af 398 Gene3D G3DSA:3.40.640.10 50 250 4.4E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS06220 5b51083a1f0e21e07522ebebecaa80af 398 Gene3D G3DSA:3.90.1150.10 251 398 9.0E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR56_RS17685 59b0e294b18783d5a7f123e434652197 248 Gene3D G3DSA:3.40.50.150 31 241 3.1E-38 T 29-03-2018 CWR56_RS17685 59b0e294b18783d5a7f123e434652197 248 Pfam PF05175 Methyltransferase small domain 33 126 3.2E-9 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWR56_RS17685 59b0e294b18783d5a7f123e434652197 248 SUPERFAMILY SSF53335 8 212 7.3E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS00200 a0f753238f78738fffd7c58805321f74 89 Gene3D G3DSA:2.30.30.30 4 88 1.6E-10 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR56_RS00200 a0f753238f78738fffd7c58805321f74 89 SUPERFAMILY SSF50104 5 87 5.19E-14 T 29-03-2018 IPR008991 Translation protein SH3-like domain CWR56_RS13295 2075910ea78a0cdfb1a92f09ddc10208 481 Pfam PF13520 Amino acid permease 17 451 1.3E-63 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS13295 2075910ea78a0cdfb1a92f09ddc10208 481 PIRSF PIRSF006060 12 479 4.0E-67 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS10575 6c7cd5a06b0f062b10713c8d38e41892 273 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 238 9.8E-49 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CWR56_RS10575 6c7cd5a06b0f062b10713c8d38e41892 273 Pfam PF02811 PHP domain 6 193 8.7E-14 T 29-03-2018 IPR004013 PHP domain GO:0003824 CWR56_RS10575 6c7cd5a06b0f062b10713c8d38e41892 273 SUPERFAMILY SSF89550 3 264 2.35E-47 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR56_RS10575 6c7cd5a06b0f062b10713c8d38e41892 273 Gene3D G3DSA:3.20.20.140 1 261 1.4E-45 T 29-03-2018 CWR56_RS10575 6c7cd5a06b0f062b10713c8d38e41892 273 SMART SM00481 4 83 2.3E-4 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR56_RS15485 851d6fc8d81c4d8b72d8d1b9e7ea1d0f 468 Pfam PF03606 C4-dicarboxylate anaerobic carrier 16 462 2.8E-121 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CWR56_RS03210 61d8c2549f639e54df0960d6806514c6 235 SUPERFAMILY SSF53335 7 196 1.41E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS03210 61d8c2549f639e54df0960d6806514c6 235 Gene3D G3DSA:3.40.50.150 4 235 3.7E-24 T 29-03-2018 CWR56_RS03210 61d8c2549f639e54df0960d6806514c6 235 Pfam PF13649 Methyltransferase domain 42 137 2.1E-11 T 29-03-2018 CWR56_RS02430 39e65b60eac916529c40a07797277bab 283 Gene3D G3DSA:1.20.1250.20 8 263 1.9E-5 T 29-03-2018 CWR56_RS02430 39e65b60eac916529c40a07797277bab 283 Pfam PF11299 Protein of unknown function (DUF3100) 20 261 3.1E-92 T 29-03-2018 IPR021450 Protein of unknown function DUF3100 CWR56_RS05350 fdd7ba73b3de35a605d7d8cc98f813d4 174 Pfam PF02620 Uncharacterized ACR, COG1399 55 172 5.6E-31 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CWR56_RS08390 1ecb9faafa98597dde702d990a2ef60d 246 Pfam PF12787 EcsC protein family 14 241 2.4E-71 T 29-03-2018 IPR024787 EcsC protein CWR56_RS08390 1ecb9faafa98597dde702d990a2ef60d 246 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 27 241 2.0E-45 T 29-03-2018 CWR56_RS04600 861a8fb4ba5f4105499e202736e337fb 249 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 245 8.4E-92 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CWR56_RS04600 861a8fb4ba5f4105499e202736e337fb 249 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 42.969 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CWR56_RS04600 861a8fb4ba5f4105499e202736e337fb 249 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 15 229 3.5E-18 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CWR56_RS04600 861a8fb4ba5f4105499e202736e337fb 249 SUPERFAMILY SSF100950 1 247 5.33E-94 T 29-03-2018 CWR56_RS04600 861a8fb4ba5f4105499e202736e337fb 249 Gene3D G3DSA:3.40.50.1360 1 249 2.5E-77 T 29-03-2018 CWR56_RS07745 7e3a8e10aefa60e2fc64d75e5e102bb2 206 Pfam PF09335 SNARE associated Golgi protein 35 151 5.9E-15 T 29-03-2018 IPR032816 SNARE associated Golgi protein CWR56_RS07195 ed68c38583e071e3d35460d6770f4728 322 Pfam PF09991 Predicted membrane protein (DUF2232) 31 135 1.8E-7 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 CWR56_RS06050 7f7a7e06737d23771fddb5e9acaa6e46 245 Gene3D G3DSA:3.40.50.1220 1 245 2.0E-60 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS06050 7f7a7e06737d23771fddb5e9acaa6e46 245 Pfam PF02146 Sir2 family 21 198 6.3E-50 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 CWR56_RS06050 7f7a7e06737d23771fddb5e9acaa6e46 245 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 5 241 58.857 T 29-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 CWR56_RS06050 7f7a7e06737d23771fddb5e9acaa6e46 245 SUPERFAMILY SSF52467 3 240 7.94E-79 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS03915 f0266e573c785a04e4b3ff7f58c15643 446 Pfam PF02447 GntP family permease 8 399 3.1E-10 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR56_RS03795 36fd315c45524430d9f115001772ba05 241 Pfam PF13649 Methyltransferase domain 72 165 4.5E-21 T 29-03-2018 CWR56_RS03795 36fd315c45524430d9f115001772ba05 241 Gene3D G3DSA:3.40.50.150 21 240 4.4E-27 T 29-03-2018 CWR56_RS03795 36fd315c45524430d9f115001772ba05 241 SUPERFAMILY SSF53335 36 230 8.98E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 ProSitePatterns PS00501 Signal peptidases I serine active site. 35 42 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 SUPERFAMILY SSF51306 28 175 7.15E-44 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 169 7.4E-46 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 Gene3D G3DSA:2.10.109.10 23 176 2.7E-40 T 29-03-2018 CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 83 95 8.5E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 127 146 8.5E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 26 42 8.5E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR56_RS06195 1cf8578f22e61dc198635b6dc133c866 176 Pfam PF00717 Peptidase S24-like 33 107 8.8E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR56_RS11765 e298e83e5f09f1bee5b3d4ca408c813b 361 Pfam PF03773 Predicted permease 28 301 8.5E-52 T 29-03-2018 IPR005524 Predicted permease DUF318 CWR56_RS01705 f16bee06f64b93a759552dbe7754bac5 232 Pfam PF02361 Cobalt transport protein 13 223 6.1E-37 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWR56_RS01705 f16bee06f64b93a759552dbe7754bac5 232 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 216 5.7E-46 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 CWR56_RS02255 3e2d867912721a6abbfa76e4909fe668 106 SUPERFAMILY SSF103481 4 102 6.93E-22 T 29-03-2018 CWR56_RS02255 3e2d867912721a6abbfa76e4909fe668 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.7E-31 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CWR56_RS08250 0c189ca9c9245d6b3cb854fddcf0db4f 88 Pfam PF12675 Protein of unknown function (DUF3795) 16 62 1.9E-10 T 29-03-2018 IPR024227 Protein of unknown function DUF3795 CWR56_RS00945 29e848e7eb26783d756960159ae31455 343 Gene3D G3DSA:1.20.1250.20 16 262 3.1E-4 T 29-03-2018 CWR56_RS00945 29e848e7eb26783d756960159ae31455 343 Pfam PF03601 Conserved hypothetical protein 698 18 320 3.8E-67 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CWR56_RS16380 cbf6a96597963c8701bd5aa4d4ca88e4 275 Pfam PF01522 Polysaccharide deacetylase 75 181 9.4E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR56_RS16380 cbf6a96597963c8701bd5aa4d4ca88e4 275 Gene3D G3DSA:3.20.20.370 38 268 2.0E-39 T 29-03-2018 CWR56_RS16380 cbf6a96597963c8701bd5aa4d4ca88e4 275 SUPERFAMILY SSF88713 75 264 4.2E-45 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR56_RS06015 f0da19f8555c18b1efec6e664e10aa62 209 Pfam PF11167 Protein of unknown function (DUF2953) 111 157 1.0E-8 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 CWR56_RS16275 0dd7823c7c8907f8dc23c83c8c6bba5c 160 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 6 107 1.3E-6 T 29-03-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CWR56_RS04645 fad05c20d86768c610617fe3546ee625 229 Pfam PF09359 VTC domain 12 224 1.4E-26 T 29-03-2018 IPR018966 VTC domain CWR56_RS04645 fad05c20d86768c610617fe3546ee625 229 Gene3D G3DSA:2.40.320.10 1 204 3.8E-18 T 29-03-2018 CWR56_RS05230 12b0d857618a9548a01ccd9726326373 376 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 19 372 1.1E-104 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CWR56_RS05230 12b0d857618a9548a01ccd9726326373 376 Pfam PF01098 Cell cycle protein 21 372 5.8E-96 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWR56_RS03110 27a90e420974e7580ba6cc0fbdc022ae 406 PRINTS PR00762 Chloride channel signature 152 171 5.5E-9 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS03110 27a90e420974e7580ba6cc0fbdc022ae 406 PRINTS PR00762 Chloride channel signature 315 335 5.5E-9 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS03110 27a90e420974e7580ba6cc0fbdc022ae 406 PRINTS PR00762 Chloride channel signature 343 359 5.5E-9 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS03110 27a90e420974e7580ba6cc0fbdc022ae 406 Gene3D G3DSA:1.10.3080.10 2 404 9.4E-54 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS03110 27a90e420974e7580ba6cc0fbdc022ae 406 Pfam PF00654 Voltage gated chloride channel 61 390 8.9E-62 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS03110 27a90e420974e7580ba6cc0fbdc022ae 406 SUPERFAMILY SSF81340 7 402 7.46E-76 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWR56_RS05205 74188a50be8a1aee785b7451a2c49cea 162 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 73 160 0.007 T 29-03-2018 CWR56_RS05205 74188a50be8a1aee785b7451a2c49cea 162 Pfam PF04093 rod shape-determining protein MreD 4 141 2.3E-10 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CWR56_RS05205 74188a50be8a1aee785b7451a2c49cea 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 4 149 8.7E-15 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CWR56_RS03320 8eb61199bbc00c0ae048796107fe8e3b 273 Gene3D G3DSA:3.60.15.10 1 273 5.5E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS03320 8eb61199bbc00c0ae048796107fe8e3b 273 SUPERFAMILY SSF56281 41 271 3.93E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CWR56_RS13835 c7716f9ba39e5190759a5cb64e5a9432 146 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 11 141 1.5E-31 T 29-03-2018 IPR007359 Positive regulator of sigma(E), RseC/MucC CWR56_RS13835 c7716f9ba39e5190759a5cb64e5a9432 146 PIRSF PIRSF004923 1 146 6.4E-36 T 29-03-2018 IPR026268 Protein RseC CWR56_RS12765 492745e2113420a03217df0e640a94e8 212 Gene3D G3DSA:1.10.10.10 157 206 1.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12765 492745e2113420a03217df0e640a94e8 212 Hamap MF_01114 Regulatory protein RecX [recX]. 42 208 16.528 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWR56_RS12765 492745e2113420a03217df0e640a94e8 212 Gene3D G3DSA:1.10.10.10 43 106 2.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS12765 492745e2113420a03217df0e640a94e8 212 Pfam PF02631 RecX family 87 203 8.6E-31 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWR56_RS12765 492745e2113420a03217df0e640a94e8 212 Gene3D G3DSA:1.10.10.10 108 152 7.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS02285 fb54f057de848e676cee5f154779a3ef 279 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 13 279 1.2E-90 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWR56_RS06835 a5fe100d7e8760c7674d73f973f9cd90 261 Pfam PF00793 DAHP synthetase I family 14 256 2.6E-73 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CWR56_RS06835 a5fe100d7e8760c7674d73f973f9cd90 261 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 15 259 1.4E-111 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWR56_RS06835 a5fe100d7e8760c7674d73f973f9cd90 261 Gene3D G3DSA:3.20.20.70 4 261 9.1E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS06835 a5fe100d7e8760c7674d73f973f9cd90 261 SUPERFAMILY SSF51569 18 259 6.87E-91 T 29-03-2018 CWR56_RS01470 06793439436ef50437b364cbccdc957f 162 SUPERFAMILY SSF52728 3 161 1.31E-45 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS01470 06793439436ef50437b364cbccdc957f 162 Gene3D G3DSA:3.40.35.10 3 159 3.7E-49 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS01470 06793439436ef50437b364cbccdc957f 162 Pfam PF03830 PTS system sorbose subfamily IIB component 4 150 2.3E-47 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS11295 dc0281a0e5dbf114759559f451e19ed2 468 Pfam PF03611 PTS system sugar-specific permease component 9 397 5.9E-77 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWR56_RS11295 dc0281a0e5dbf114759559f451e19ed2 468 PIRSF PIRSF006304 1 464 3.7E-155 T 29-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 CWR56_RS09145 5d00eb4f48f00758f552a8f85b08810e 173 Gene3D G3DSA:1.10.10.10 46 137 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09145 5d00eb4f48f00758f552a8f85b08810e 173 Pfam PF01047 MarR family 49 106 2.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS09145 5d00eb4f48f00758f552a8f85b08810e 173 SUPERFAMILY SSF46785 35 162 1.05E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS09145 5d00eb4f48f00758f552a8f85b08810e 173 SMART SM00347 42 146 5.3E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR56_RS10410 1734432f8c0f9989bb5357d1e677b388 319 Pfam PF04892 VanZ like family 19 143 3.7E-22 T 29-03-2018 IPR006976 VanZ-like CWR56_RS15060 bd491bd2d500d8de2d12167b06ea448d 314 Pfam PF08902 Domain of unknown function (DUF1848) 2 263 3.6E-103 T 29-03-2018 IPR014998 Protein of unknown function DUF1848 CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 Gene3D G3DSA:3.40.50.300 310 738 3.9E-33 T 29-03-2018 CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 Gene3D G3DSA:3.40.50.300 1 309 3.0E-38 T 29-03-2018 CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 SUPERFAMILY SSF52540 4 472 2.49E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 SUPERFAMILY SSF52540 682 735 2.49E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 SUPERFAMILY SSF52540 527 642 2.49E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 Pfam PF13361 UvrD-like helicase C-terminal domain 312 704 1.1E-23 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR56_RS04760 1076f4abfacadf8abfdda37817a0a4ba 739 Pfam PF00580 UvrD/REP helicase N-terminal domain 9 301 4.4E-46 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR56_RS03875 20e4581f5308187b8c28e08557db0540 128 Pfam PF01925 Sulfite exporter TauE/SafE 20 128 3.9E-21 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR56_RS03875 20e4581f5308187b8c28e08557db0540 128 Gene3D G3DSA:1.20.1250.20 12 128 0.0016 T 29-03-2018 CWR56_RS16940 9d58b4868e20775b9bdf0a7a60b60ff8 256 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 79 88 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CWR56_RS16940 9d58b4868e20775b9bdf0a7a60b60ff8 256 Gene3D G3DSA:1.20.1080.10 6 256 3.8E-80 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWR56_RS16940 9d58b4868e20775b9bdf0a7a60b60ff8 256 Pfam PF01226 Formate/nitrite transporter 10 249 2.1E-75 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CWR56_RS13715 458e1b9f3d53190de81a2ecc28bd2146 282 Pfam PF01261 Xylose isomerase-like TIM barrel 28 222 3.3E-14 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS13715 458e1b9f3d53190de81a2ecc28bd2146 282 Gene3D G3DSA:3.20.20.150 1 282 1.5E-39 T 29-03-2018 CWR56_RS13715 458e1b9f3d53190de81a2ecc28bd2146 282 SUPERFAMILY SSF51658 8 280 9.67E-69 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR56_RS04045 3806e3978351851ca8fde26b0a39daa2 129 Gene3D G3DSA:1.10.10.10 1 71 1.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04045 3806e3978351851ca8fde26b0a39daa2 129 SUPERFAMILY SSF46785 1 121 1.45E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS04045 3806e3978351851ca8fde26b0a39daa2 129 Pfam PF01475 Ferric uptake regulator family 1 115 1.9E-28 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 35 111 1.1E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 237 258 4.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 298 342 2.0E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 112 151 1.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 259 297 4.1E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 205 236 3.7E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS00710 8d580798a1ec47deb20b035946f19b65 346 Gene3D G3DSA:2.60.40.10 152 204 6.2E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS08575 10989af61d817a1798f790dcbc622408 462 Gene3D G3DSA:2.130.10.130 28 212 5.3E-9 T 29-03-2018 CWR56_RS08575 10989af61d817a1798f790dcbc622408 462 SUPERFAMILY SSF69318 72 203 2.09E-8 T 29-03-2018 CWR56_RS16610 d645278eeb5c151bccda7637230f6e5d 175 Pfam PF02417 Chromate transporter 6 169 2.9E-41 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CWR56_RS04035 50d4524dcb1dcc6a18fcb620e2828f18 260 Pfam PF12730 ABC-2 family transporter protein 4 183 1.0E-43 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS13360 ff13ede82875ef758204a56bcb5244fd 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 145 5.9E-61 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CWR56_RS13360 ff13ede82875ef758204a56bcb5244fd 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 79.073 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CWR56_RS13360 ff13ede82875ef758204a56bcb5244fd 153 Pfam PF03477 ATP cone domain 49 135 1.5E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWR56_RS09825 91bf3d1fa4557320d6967091beec6477 361 Pfam PF01594 AI-2E family transporter 18 355 4.2E-59 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS11970 fa337df68fc070e94f6668ec9fd533ab 464 SUPERFAMILY SSF52540 216 389 1.67E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11970 fa337df68fc070e94f6668ec9fd533ab 464 Gene3D G3DSA:3.40.50.300 87 391 3.4E-20 T 29-03-2018 CWR56_RS18145 59dd10720062bd87bc115e5aefec754c 274 Pfam PF02517 CAAX protease self-immunity 124 227 7.3E-11 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR56_RS12160 9ca2f9b4e550fe4f65e51d2897552d52 89 Gene3D G3DSA:2.20.28.20 5 40 0.0011 T 29-03-2018 CWR56_RS12160 9ca2f9b4e550fe4f65e51d2897552d52 89 Gene3D G3DSA:2.20.28.20 41 71 0.24 T 29-03-2018 CWR56_RS12160 9ca2f9b4e550fe4f65e51d2897552d52 89 Pfam PF12773 Double zinc ribbon 12 63 1.1E-6 T 29-03-2018 IPR025874 Double zinc ribbon CWR56_RS04370 b78f9824db250a7463988ac5f7a7aea1 137 Gene3D G3DSA:3.60.90.10 1 127 9.1E-45 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CWR56_RS04370 b78f9824db250a7463988ac5f7a7aea1 137 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 114 2.1E-44 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CWR56_RS04370 b78f9824db250a7463988ac5f7a7aea1 137 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 118 30.271 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CWR56_RS04370 b78f9824db250a7463988ac5f7a7aea1 137 Pfam PF02675 S-adenosylmethionine decarboxylase 9 114 4.3E-39 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CWR56_RS04370 b78f9824db250a7463988ac5f7a7aea1 137 SUPERFAMILY SSF56276 4 117 2.35E-39 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CWR56_RS18205 2287bcf6f8c944e00e6f89a67ceb84aa 364 SUPERFAMILY SSF51445 2 243 1.16E-92 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CWR56_RS18205 2287bcf6f8c944e00e6f89a67ceb84aa 364 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 359 7.7E-140 T 29-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CWR56_RS18205 2287bcf6f8c944e00e6f89a67ceb84aa 364 Gene3D G3DSA:2.40.100.10 245 360 1.0E-34 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS18205 2287bcf6f8c944e00e6f89a67ceb84aa 364 SUPERFAMILY SSF50891 247 360 3.34E-33 T 29-03-2018 IPR029000 Cyclophilin-like domain CWR56_RS18205 2287bcf6f8c944e00e6f89a67ceb84aa 364 Gene3D G3DSA:3.20.20.70 4 239 4.2E-95 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS01840 c6c5976f108b6ba79d1321c9dc429bcf 287 SUPERFAMILY SSF103481 188 286 2.88E-8 T 29-03-2018 CWR56_RS01840 c6c5976f108b6ba79d1321c9dc429bcf 287 SUPERFAMILY SSF103481 41 137 6.41E-13 T 29-03-2018 CWR56_RS01840 c6c5976f108b6ba79d1321c9dc429bcf 287 Pfam PF00892 EamA-like transporter family 155 286 8.1E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS01840 c6c5976f108b6ba79d1321c9dc429bcf 287 Pfam PF00892 EamA-like transporter family 7 135 4.0E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR56_RS00110 4713e815af7a9377c48aa2888b4e491f 111 Pfam PF00237 Ribosomal protein L22p/L17e 5 108 2.0E-40 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00110 4713e815af7a9377c48aa2888b4e491f 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.4E-44 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00110 4713e815af7a9377c48aa2888b4e491f 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR56_RS00110 4713e815af7a9377c48aa2888b4e491f 111 SUPERFAMILY SSF54843 1 111 1.57E-45 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CWR56_RS00110 4713e815af7a9377c48aa2888b4e491f 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.197 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR56_RS00110 4713e815af7a9377c48aa2888b4e491f 111 Gene3D G3DSA:3.90.470.10 1 111 7.7E-47 T 29-03-2018 CWR56_RS08630 8d4e3fd12ac501b59f6ae623824c5dfd 318 SUPERFAMILY SSF51735 2 315 4.35E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS08630 8d4e3fd12ac501b59f6ae623824c5dfd 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 1.9E-25 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR56_RS08630 8d4e3fd12ac501b59f6ae623824c5dfd 318 Gene3D G3DSA:3.40.50.720 2 315 8.2E-34 T 29-03-2018 CWR56_RS05715 2d3bc4944597dc3f963e658967ef1073 169 Pfam PF04892 VanZ like family 13 134 3.6E-22 T 29-03-2018 IPR006976 VanZ-like CWR56_RS17755 5928fddf44a9c154f895c39d3fb5b3a8 196 Pfam PF12822 ECF transporter, substrate-specific component 14 187 3.4E-31 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CWR56_RS02210 9cdc95a2be2803eea4b5950b1d3d5ae7 258 TIGRFAM TIGR03733 lanti_perm_MutG: lantibiotic protection ABC transporter permease subunit, MutG family 3 256 1.0E-84 T 29-03-2018 IPR022294 Lantibiotic protection ABC transporter permease subunit, MutG family CWR56_RS02210 9cdc95a2be2803eea4b5950b1d3d5ae7 258 Pfam PF12730 ABC-2 family transporter protein 4 154 7.8E-13 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS13805 884513a15dd9c4a4334bac83af988f4c 354 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 19 328 6.9E-37 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR56_RS13805 884513a15dd9c4a4334bac83af988f4c 354 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 14 344 1.4E-22 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR56_RS13995 07013ec50ed082a77d2b91deeffd89d8 132 Pfam PF02082 Transcriptional regulator 1 82 1.1E-6 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CWR56_RS13995 07013ec50ed082a77d2b91deeffd89d8 132 SUPERFAMILY SSF46785 1 131 5.19E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS13995 07013ec50ed082a77d2b91deeffd89d8 132 Gene3D G3DSA:1.10.10.10 1 132 4.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS06810 baa7f49eb1b606f5d4eae1cb5d4b81e8 233 Gene3D G3DSA:3.30.460.10 5 117 7.7E-10 T 29-03-2018 CWR56_RS09360 3779c6ff5755c8e7aab8969818fefec4 463 Pfam PF03594 Benzoate membrane transport protein 63 161 6.0E-5 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CWR56_RS09170 acd56732b74333f897cdab8c1ff99d9d 452 Gene3D G3DSA:3.90.20.10 133 317 4.8E-5 T 29-03-2018 CWR56_RS14890 3bd287f92b84c35a09ca9b5638f72cde 208 SUPERFAMILY SSF55136 18 194 9.94E-8 T 29-03-2018 CWR56_RS14890 3bd287f92b84c35a09ca9b5638f72cde 208 PIRSF PIRSF031644 1 207 5.4E-79 T 29-03-2018 IPR008319 Uncharacterised conserved protein UCP031644 CWR56_RS14890 3bd287f92b84c35a09ca9b5638f72cde 208 Pfam PF06445 GyrI-like small molecule binding domain 18 201 2.4E-22 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CWR56_RS14890 3bd287f92b84c35a09ca9b5638f72cde 208 Gene3D G3DSA:3.20.80.10 1 205 3.3E-74 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CWR56_RS02895 d9747c4d5824ffa55a40f73520f2b5f8 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 1.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR56_RS02895 d9747c4d5824ffa55a40f73520f2b5f8 193 Gene3D G3DSA:1.10.10.60 44 142 3.8E-5 T 29-03-2018 CWR56_RS02895 d9747c4d5824ffa55a40f73520f2b5f8 193 Gene3D G3DSA:1.10.10.60 4 43 4.9E-10 T 29-03-2018 CWR56_RS02895 d9747c4d5824ffa55a40f73520f2b5f8 193 SUPERFAMILY SSF46689 5 67 4.26E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR56_RS11190 4942db83348aae9b761fcf88e39f7d00 349 Pfam PF13303 Phosphotransferase system, EIIC 28 347 9.4E-109 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS10230 49e2b358e2e10fb53b251a07c0f1934d 374 Pfam PF12725 Protein of unknown function (DUF3810) 34 365 7.1E-102 T 29-03-2018 IPR024294 Protein of unknown function DUF3810 CWR56_RS11755 d1a8dcce9a454a7a42bd92d6d261d7e5 363 SUPERFAMILY SSF53850 40 264 4.06E-31 T 29-03-2018 CWR56_RS11755 d1a8dcce9a454a7a42bd92d6d261d7e5 363 Gene3D G3DSA:3.40.190.10 147 332 5.7E-26 T 29-03-2018 CWR56_RS11755 d1a8dcce9a454a7a42bd92d6d261d7e5 363 Gene3D G3DSA:3.40.190.10 38 142 3.8E-12 T 29-03-2018 CWR56_RS11755 d1a8dcce9a454a7a42bd92d6d261d7e5 363 Pfam PF09084 NMT1/THI5 like 58 262 1.7E-18 T 29-03-2018 IPR015168 SsuA/THI5-like CWR56_RS16730 550b89c869e1fd785770cc9c9589791b 193 Pfam PF04647 Accessory gene regulator B 7 183 3.4E-41 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR56_RS16730 550b89c869e1fd785770cc9c9589791b 193 SMART SM00793 4 191 6.4E-10 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR56_RS03340 315804654589fe9612650c6c7bfa01b2 580 Gene3D G3DSA:1.10.1370.10 301 558 1.2E-8 T 29-03-2018 CWR56_RS03340 315804654589fe9612650c6c7bfa01b2 580 Gene3D G3DSA:1.10.1370.10 67 289 4.0E-12 T 29-03-2018 CWR56_RS03340 315804654589fe9612650c6c7bfa01b2 580 SUPERFAMILY SSF55486 46 533 5.37E-49 T 29-03-2018 CWR56_RS17690 0f9eae6b7e000bbbc935adcfbaec9541 297 Pfam PF04468 PSP1 C-terminal conserved region 61 146 4.5E-32 T 29-03-2018 IPR007557 PSP1, C-terminal CWR56_RS12605 0f22357a41583a890e9b2cbdfd202c57 467 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 467 210.059 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CWR56_RS12605 0f22357a41583a890e9b2cbdfd202c57 467 Pfam PF03841 L-seryl-tRNA selenium transferase 86 450 3.7E-169 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CWR56_RS12605 0f22357a41583a890e9b2cbdfd202c57 467 SUPERFAMILY SSF53383 81 466 3.78E-53 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR56_RS12605 0f22357a41583a890e9b2cbdfd202c57 467 Pfam PF12390 Selenocysteine synthase N terminal 7 46 1.9E-9 T 29-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CWR56_RS12605 0f22357a41583a890e9b2cbdfd202c57 467 Gene3D G3DSA:3.40.640.10 98 356 5.5E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR56_RS12605 0f22357a41583a890e9b2cbdfd202c57 467 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 8 463 7.4E-192 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CWR56_RS11915 ac6bd86d11ca5fa723f8542cb9ca54f2 734 Gene3D G3DSA:1.10.287.700 120 615 1.1E-4 T 29-03-2018 CWR56_RS06290 3fba7f6cec6f3843d86544a54b446cdb 273 Pfam PF08543 Phosphomethylpyrimidine kinase 28 254 3.4E-26 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CWR56_RS06290 3fba7f6cec6f3843d86544a54b446cdb 273 SUPERFAMILY SSF53613 1 270 5.92E-57 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS06290 3fba7f6cec6f3843d86544a54b446cdb 273 Gene3D G3DSA:3.40.1190.20 1 257 5.5E-36 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS03495 cb42bcbf82231d177cc8313a5dd812b7 293 Pfam PF02219 Methylenetetrahydrofolate reductase 4 292 1.1E-35 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR56_RS03495 cb42bcbf82231d177cc8313a5dd812b7 293 Gene3D G3DSA:3.20.20.220 1 293 1.9E-57 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CWR56_RS03495 cb42bcbf82231d177cc8313a5dd812b7 293 SUPERFAMILY SSF51730 1 292 1.33E-68 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CWR56_RS03090 29a45551416f754184f85859a661ef16 124 SMART SM00345 17 76 6.3E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03090 29a45551416f754184f85859a661ef16 124 Gene3D G3DSA:1.10.10.10 1 78 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS03090 29a45551416f754184f85859a661ef16 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 6.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR56_RS03090 29a45551416f754184f85859a661ef16 124 SUPERFAMILY SSF46785 5 84 1.99E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11125 4bb5065d716ccf06707d33f3a5df5699 200 Gene3D G3DSA:3.40.50.1820 1 200 5.8E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS11125 4bb5065d716ccf06707d33f3a5df5699 200 SUPERFAMILY SSF53474 4 194 7.79E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS17340 eeac1c39e36a4483485ae2c868c08cc9 271 Gene3D G3DSA:2.40.50.100 173 241 4.7E-7 T 29-03-2018 CWR56_RS17340 eeac1c39e36a4483485ae2c868c08cc9 271 Gene3D G3DSA:3.40.50.720 2 172 4.2E-4 T 29-03-2018 CWR56_RS17340 eeac1c39e36a4483485ae2c868c08cc9 271 TIGRFAM TIGR03309 matur_yqeB: selenium-dependent molybdenum hydroxylase system protein, YqeB family 5 264 2.0E-104 T 29-03-2018 IPR017695 Selenium-dependent molybdenum hydroxylase system protein, YqeB family CWR56_RS17340 eeac1c39e36a4483485ae2c868c08cc9 271 SUPERFAMILY SSF51230 178 237 5.76E-7 T 29-03-2018 IPR011053 Single hybrid motif CWR56_RS11815 d24d63a56e748c908505aed281a7929f 168 SUPERFAMILY SSF55811 2 148 3.93E-32 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR56_RS11815 d24d63a56e748c908505aed281a7929f 168 Pfam PF00293 NUDIX domain 29 143 2.7E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR56_RS11815 d24d63a56e748c908505aed281a7929f 168 Gene3D G3DSA:3.90.79.10 1 165 8.8E-26 T 29-03-2018 CWR56_RS11815 d24d63a56e748c908505aed281a7929f 168 ProSitePatterns PS00893 Nudix box signature. 65 86 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR56_RS08465 54ed4f4ed4be8d62d559be9371b672a6 260 Pfam PF02567 Phenazine biosynthesis-like protein 6 254 3.8E-55 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CWR56_RS08465 54ed4f4ed4be8d62d559be9371b672a6 260 Gene3D G3DSA:3.10.310.10 121 246 1.3E-32 T 29-03-2018 CWR56_RS08465 54ed4f4ed4be8d62d559be9371b672a6 260 Gene3D G3DSA:3.10.310.10 1 120 9.4E-27 T 29-03-2018 CWR56_RS08465 54ed4f4ed4be8d62d559be9371b672a6 260 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 258 1.9E-35 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CWR56_RS08465 54ed4f4ed4be8d62d559be9371b672a6 260 SUPERFAMILY SSF54506 2 257 1.59E-73 T 29-03-2018 CWR56_RS08465 54ed4f4ed4be8d62d559be9371b672a6 260 PIRSF PIRSF016184 1 258 7.9E-54 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CWR56_RS17255 c1bedcaa4aed79cf89b938a6ed18c7b5 95 Gene3D G3DSA:1.10.1220.10 7 57 5.5E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWR56_RS17255 c1bedcaa4aed79cf89b938a6ed18c7b5 95 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 46 9.2E-5 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CWR56_RS10870 4997813167c4b4c0393276b7e77d185f 64 Pfam PF12655 Domain of unknown function (DUF3787) 12 63 4.3E-23 T 29-03-2018 IPR024209 Protein of unknown function DUF3787 CWR56_RS06925 a01bfef233ad41b730b1dfcf396a7908 739 Gene3D G3DSA:1.10.287.950 237 310 0.064 T 29-03-2018 CWR56_RS06925 a01bfef233ad41b730b1dfcf396a7908 739 Gene3D G3DSA:1.20.1170.10 334 575 9.0E-24 T 29-03-2018 CWR56_RS06925 a01bfef233ad41b730b1dfcf396a7908 739 Pfam PF12698 ABC-2 family transporter protein 46 714 6.9E-10 T 29-03-2018 CWR56_RS06925 a01bfef233ad41b730b1dfcf396a7908 739 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 35 196 4.4E-45 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CWR56_RS06925 a01bfef233ad41b730b1dfcf396a7908 739 Gene3D G3DSA:3.40.1710.10 73 236 2.6E-25 T 29-03-2018 CWR56_RS06925 a01bfef233ad41b730b1dfcf396a7908 739 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 520 716 4.2E-45 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CWR56_RS16445 ac641b1bf84dffbd0f63fab60b8d7741 221 PRINTS PR01837 MgtC/SapB protein signature 94 118 2.3E-42 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS16445 ac641b1bf84dffbd0f63fab60b8d7741 221 PRINTS PR01837 MgtC/SapB protein signature 35 53 2.3E-42 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS16445 ac641b1bf84dffbd0f63fab60b8d7741 221 PRINTS PR01837 MgtC/SapB protein signature 67 89 2.3E-42 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS16445 ac641b1bf84dffbd0f63fab60b8d7741 221 PRINTS PR01837 MgtC/SapB protein signature 16 35 2.3E-42 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS16445 ac641b1bf84dffbd0f63fab60b8d7741 221 Pfam PF02308 MgtC family 13 139 1.9E-38 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CWR56_RS08185 d8fb66fb1b01deec5fa587c3ffaeeb54 123 Pfam PF13380 CoA binding domain 8 114 8.9E-17 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CWR56_RS08185 d8fb66fb1b01deec5fa587c3ffaeeb54 123 SUPERFAMILY SSF51735 3 121 1.38E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CWR56_RS08185 d8fb66fb1b01deec5fa587c3ffaeeb54 123 Gene3D G3DSA:3.40.50.720 1 111 6.5E-10 T 29-03-2018 CWR56_RS17630 51adbaae0dc02346416613bd04642f50 361 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 2 361 2.8E-131 T 29-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CWR56_RS17630 51adbaae0dc02346416613bd04642f50 361 PIRSF PIRSF007313 1 361 6.7E-170 T 29-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CWR56_RS15395 b90869882f16fdcc21dc3152486ac87b 105 SUPERFAMILY SSF52794 5 104 1.14E-30 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15395 b90869882f16fdcc21dc3152486ac87b 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 97 9.4E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15395 b90869882f16fdcc21dc3152486ac87b 105 Gene3D G3DSA:3.40.50.2300 4 105 2.5E-34 T 29-03-2018 CWR56_RS00830 aa631555263d99ae38129b8f8fae735b 458 PIRSF PIRSF006603 2 458 9.5E-70 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS00830 aa631555263d99ae38129b8f8fae735b 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 416 5.3E-64 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS00830 aa631555263d99ae38129b8f8fae735b 458 Pfam PF01554 MatE 24 183 1.7E-33 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS00830 aa631555263d99ae38129b8f8fae735b 458 Pfam PF01554 MatE 262 414 2.1E-17 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS03415 81be8f86988cb557ec936edf6830791d 137 Pfam PF04463 Protein of unknown function (DUF523) 2 135 1.8E-45 T 29-03-2018 IPR007553 Domain of unknown function DUF523 CWR56_RS03920 1ea45568976f954b1c8a47f49a0d780a 412 SUPERFAMILY SSF89796 5 403 3.27E-100 T 29-03-2018 IPR023606 CoA-transferase family III domain CWR56_RS03920 1ea45568976f954b1c8a47f49a0d780a 412 Gene3D G3DSA:3.40.50.10540 3 411 2.5E-105 T 29-03-2018 IPR023606 CoA-transferase family III domain CWR56_RS03920 1ea45568976f954b1c8a47f49a0d780a 412 Pfam PF02515 CoA-transferase family III 8 378 4.9E-93 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CWR56_RS12625 3260c5e9feb7110947d3564eb093e1cf 112 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 89 8.9E-26 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 CWR56_RS12625 3260c5e9feb7110947d3564eb093e1cf 112 Gene3D G3DSA:3.40.50.2300 9 90 6.9E-4 T 29-03-2018 CWR56_RS04825 03cc4382425ccc69ec95e861704333f7 228 Pfam PF13346 ABC-2 family transporter protein 3 220 7.9E-19 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CWR56_RS07500 50d1e7782beff48738cad4b99d203de5 250 Pfam PF00561 alpha/beta hydrolase fold 20 126 3.2E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR56_RS07500 50d1e7782beff48738cad4b99d203de5 250 SUPERFAMILY SSF53474 6 249 3.33E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS07500 50d1e7782beff48738cad4b99d203de5 250 Gene3D G3DSA:3.40.50.1820 2 249 3.4E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS08345 7306682be498687d3fc2400f587f765f 428 PIRSF PIRSF011588 1 428 4.5E-218 T 29-03-2018 IPR016585 Glycine/sarcosine/betaine reductase, component B, fused alpha/beta GO:0050485|GO:0055114 CWR56_RS08345 7306682be498687d3fc2400f587f765f 428 Gene3D G3DSA:2.160.10.10 2 346 2.0E-5 T 29-03-2018 CWR56_RS08345 7306682be498687d3fc2400f587f765f 428 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 1 426 1.3E-199 T 29-03-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CWR56_RS14830 e2936db168078c000de2fbf69e7ffa75 625 Pfam PF09706 CRISPR-associated protein (Cas_CXXC_CXXC) 267 331 2.6E-24 T 29-03-2018 IPR019121 CRISPR-associated protein, CXXC-CXXC domain CWR56_RS14830 e2936db168078c000de2fbf69e7ffa75 625 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 273 573 2.5E-27 T 29-03-2018 IPR010180 CRISPR-associated protein, CXXC-CXXC CWR56_RS07000 44ddaaedfaeede358b52965a08835924 199 Gene3D G3DSA:3.40.190.10 1 194 5.0E-5 T 29-03-2018 CWR56_RS05560 a4e734a220ea93fb274d315f112006bb 230 Pfam PF00535 Glycosyl transferase family 2 6 126 9.9E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR56_RS05560 a4e734a220ea93fb274d315f112006bb 230 SUPERFAMILY SSF53448 4 222 2.22E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS05560 a4e734a220ea93fb274d315f112006bb 230 Gene3D G3DSA:3.90.550.10 3 229 2.4E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR56_RS03840 33efbb46b43913938bfbb94288df56d6 215 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 8 204 3.7E-44 T 29-03-2018 IPR010178 Integral membrane protein 1906 CWR56_RS03840 33efbb46b43913938bfbb94288df56d6 215 Pfam PF07314 Protein of unknown function (DUF1461) 7 180 1.8E-48 T 29-03-2018 IPR010178 Integral membrane protein 1906 CWR56_RS02370 4439bf843821d6b2356c581e3a697614 164 Pfam PF12821 Threonine/Serine exporter, ThrE 7 133 8.4E-36 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE CWR56_RS03810 ac43a6249229cc8918a8ef4768383ce7 132 Gene3D G3DSA:3.40.140.10 1 130 7.2E-30 T 29-03-2018 CWR56_RS03810 ac43a6249229cc8918a8ef4768383ce7 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 27 98 3.2E-7 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR56_RS03810 ac43a6249229cc8918a8ef4768383ce7 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 94 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR56_RS03810 ac43a6249229cc8918a8ef4768383ce7 132 SUPERFAMILY SSF53927 1 126 1.59E-28 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 Gene3D G3DSA:3.40.250.10 159 283 5.2E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 Pfam PF00581 Rhodanese-like domain 161 271 4.7E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 Pfam PF00581 Rhodanese-like domain 6 128 1.0E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 Gene3D G3DSA:3.40.250.10 2 150 1.1E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 SMART SM00450 157 276 1.1E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 SMART SM00450 6 132 6.0E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 SUPERFAMILY SSF52821 152 281 1.57E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS07270 5bed9900ff6821a6634128546eb634dd 283 SUPERFAMILY SSF52821 4 142 6.29E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CWR56_RS04315 9441b48ab0a3031b3e8458235e0906b5 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 267 2.8E-27 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWR56_RS04315 9441b48ab0a3031b3e8458235e0906b5 300 Gene3D G3DSA:1.10.3470.10 1 271 9.6E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR56_RS18225 a424f274fe7151c1f1cb99c1c4af73d3 103 SUPERFAMILY SSF52794 1 101 1.46E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS18225 a424f274fe7151c1f1cb99c1c4af73d3 103 Gene3D G3DSA:3.40.50.2300 2 103 3.1E-38 T 29-03-2018 CWR56_RS18225 a424f274fe7151c1f1cb99c1c4af73d3 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 1.6E-24 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR56_RS15165 bb6beafbed40ac6b3f9944bfdf3d2dc1 324 Pfam PF06081 Aromatic acid exporter family member 1 7 143 1.2E-32 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CWR56_RS15165 bb6beafbed40ac6b3f9944bfdf3d2dc1 324 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 148 309 6.1E-39 T 29-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CWR56_RS15155 bd7eee48c44d7a89ac9cbc81bbd6a662 267 Gene3D G3DSA:2.60.40.10 136 202 0.09 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS15155 bd7eee48c44d7a89ac9cbc81bbd6a662 267 Gene3D G3DSA:2.60.40.10 92 135 2.3E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS15155 bd7eee48c44d7a89ac9cbc81bbd6a662 267 Gene3D G3DSA:2.60.40.10 47 91 1.2E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS15155 bd7eee48c44d7a89ac9cbc81bbd6a662 267 Gene3D G3DSA:2.60.40.10 3 46 5.3E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CWR56_RS15390 49bd44d4289b04e230ec07ff59a7f8ce 410 Pfam PF02378 Phosphotransferase system, EIIC 31 331 2.3E-17 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15390 49bd44d4289b04e230ec07ff59a7f8ce 410 PIRSF PIRSF006351 1 410 1.2E-83 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS02670 74798a237fc1bf3073f9b8742ea4ade5 416 Gene3D G3DSA:1.20.1250.20 6 199 1.5E-17 T 29-03-2018 CWR56_RS02670 74798a237fc1bf3073f9b8742ea4ade5 416 Gene3D G3DSA:1.20.1250.20 216 413 7.9E-11 T 29-03-2018 CWR56_RS02670 74798a237fc1bf3073f9b8742ea4ade5 416 Pfam PF05977 Transmembrane secretion effector 9 405 4.1E-21 T 29-03-2018 IPR010290 Transmembrane secretion effector CWR56_RS02670 74798a237fc1bf3073f9b8742ea4ade5 416 SUPERFAMILY SSF103473 9 410 1.31E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain CWR56_RS04755 41e8ee08f30335b0e8c6a9525f99451a 637 Gene3D G3DSA:3.40.50.300 242 532 4.4E-4 T 29-03-2018 CWR56_RS07230 7515df9dba5be9e0d31ea611f031530d 410 Pfam PF02687 FtsX-like permease family 316 404 3.7E-15 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS07230 7515df9dba5be9e0d31ea611f031530d 410 Pfam PF12704 MacB-like periplasmic core domain 19 248 2.3E-14 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CWR56_RS05555 01793b8549d578fd50c8061fa3231655 291 Pfam PF11382 Copper transport outer membrane protein, MctB 3 288 8.7E-33 T 29-03-2018 IPR021522 Copper transporter MctB GO:0006810 CWR56_RS05555 01793b8549d578fd50c8061fa3231655 291 Gene3D G3DSA:1.20.120.560 29 228 0.0013 T 29-03-2018 CWR56_RS16750 36e39888579036a0f78af01d4c03f54b 191 Pfam PF06353 Protein of unknown function (DUF1062) 37 164 1.5E-44 T 29-03-2018 IPR009412 Protein of unknown function DUF1062 CWR56_RS06260 437f8158ad4e38a130c252c17d4096c3 356 Pfam PF13349 Putative adhesin 55 233 6.4E-11 T 29-03-2018 IPR025164 Putative adhesin CWR56_RS06640 1737399ee64e377b851c1041bcda1349 451 PIRSF PIRSF006603 1 445 3.9E-66 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS06640 1737399ee64e377b851c1041bcda1349 451 Pfam PF01554 MatE 257 403 3.3E-18 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS06640 1737399ee64e377b851c1041bcda1349 451 Pfam PF01554 MatE 23 184 1.0E-24 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS16715 4d6d8c6852c24d84c6a26a5022851765 290 SUPERFAMILY SSF52540 8 215 1.52E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS16715 4d6d8c6852c24d84c6a26a5022851765 290 SMART SM00382 28 209 2.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS16715 4d6d8c6852c24d84c6a26a5022851765 290 Gene3D G3DSA:3.40.50.300 2 234 7.6E-61 T 29-03-2018 CWR56_RS16715 4d6d8c6852c24d84c6a26a5022851765 290 Pfam PF00005 ABC transporter 20 162 6.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS03160 ba667f5486723a77e0cb42cf3e720437 89 Pfam PF12675 Protein of unknown function (DUF3795) 5 61 1.4E-7 T 29-03-2018 IPR024227 Protein of unknown function DUF3795 CWR56_RS16390 5ab083a667da4627910afcbcc91de318 289 Pfam PF06081 Aromatic acid exporter family member 1 5 143 2.0E-21 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CWR56_RS05445 053b865108d8f617c6a38805a5c42a79 65 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 1 64 2.1E-22 T 29-03-2018 IPR009570 Stage III sporulation protein AC CWR56_RS05445 053b865108d8f617c6a38805a5c42a79 65 Pfam PF06686 Stage III sporulation protein AC/AD protein family 6 61 8.2E-17 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CWR56_RS12395 f405f59a48d741423e25625dc4f3c1f5 337 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 21 255 1.5E-5 T 29-03-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CWR56_RS12395 f405f59a48d741423e25625dc4f3c1f5 337 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 21 258 8.8E-20 T 29-03-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CWR56_RS03155 04002687e3ab2989ea04945f06ee8583 81 Gene3D G3DSA:1.10.150.20 2 81 8.9E-22 T 29-03-2018 CWR56_RS03155 04002687e3ab2989ea04945f06ee8583 81 Pfam PF11731 Pathogenicity locus 3 81 2.5E-25 T 29-03-2018 IPR021725 Pathogenicity locus CWR56_RS13200 d8504ee109ac787ee1666481fef4663b 467 PIRSF PIRSF006060 1 467 2.4E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS13200 d8504ee109ac787ee1666481fef4663b 467 Pfam PF13520 Amino acid permease 6 440 3.9E-61 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR56_RS14255 da2e5df89e2523d07bc2c4da137d5664 107 Pfam PF07561 Domain of Unknown Function (DUF1540) 4 42 1.7E-8 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CWR56_RS14255 da2e5df89e2523d07bc2c4da137d5664 107 Pfam PF07561 Domain of Unknown Function (DUF1540) 65 104 2.5E-11 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CWR56_RS09340 a047f0f4bc552fdb84b794c0f09c1ea6 221 SMART SM00382 32 218 3.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS09340 a047f0f4bc552fdb84b794c0f09c1ea6 221 Pfam PF00005 ABC transporter 23 169 4.8E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS09340 a047f0f4bc552fdb84b794c0f09c1ea6 221 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR56_RS09340 a047f0f4bc552fdb84b794c0f09c1ea6 221 SUPERFAMILY SSF52540 3 220 1.33E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS09340 a047f0f4bc552fdb84b794c0f09c1ea6 221 Gene3D G3DSA:3.40.50.300 1 221 1.3E-61 T 29-03-2018 CWR56_RS11260 ca06086a551fe24444b7c2dac9629d98 353 Pfam PF01594 AI-2E family transporter 18 344 3.5E-44 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS11260 ca06086a551fe24444b7c2dac9629d98 353 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 15 349 1.9E-76 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI CWR56_RS07415 77a23c44aa429884203a28843e4d8928 79 Pfam PF13710 ACT domain 16 72 1.7E-12 T 29-03-2018 CWR56_RS07415 77a23c44aa429884203a28843e4d8928 79 Gene3D G3DSA:3.30.70.260 15 79 6.5E-4 T 29-03-2018 CWR56_RS01485 3c9f67e75ecbfc91fae1858692138724 159 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 27 155 4.9E-10 T 29-03-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase CWR56_RS06380 e54027b10771f9ce40391eb8e6d631ab 108 Pfam PF10844 Protein of unknown function (DUF2577) 11 104 9.0E-14 T 29-03-2018 IPR022555 Protein of unknown function, DUF2577 CWR56_RS14010 f9f4ad31b0b4437b29a23ee99900597c 214 Pfam PF01255 Putative undecaprenyl diphosphate synthase 10 210 4.6E-38 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS14010 f9f4ad31b0b4437b29a23ee99900597c 214 Gene3D G3DSA:3.40.1180.10 1 214 8.2E-42 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS14010 f9f4ad31b0b4437b29a23ee99900597c 214 SUPERFAMILY SSF64005 2 207 8.24E-46 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS14010 f9f4ad31b0b4437b29a23ee99900597c 214 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 3 207 2.3E-32 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 Gene3D G3DSA:3.40.50.300 554 704 7.1E-27 T 29-03-2018 CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 SUPERFAMILY SSF52540 451 697 1.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 SUPERFAMILY SSF52540 218 369 1.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 Pfam PF13245 AAA domain 230 521 2.9E-7 T 29-03-2018 CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 Pfam PF13361 UvrD-like helicase C-terminal domain 542 634 1.1E-6 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 Pfam PF13538 UvrD-like helicase C-terminal domain 646 690 3.0E-8 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CWR56_RS02090 0566cfd5406f255f8310b5b3717b156a 704 Gene3D G3DSA:3.40.50.300 219 553 7.6E-27 T 29-03-2018 CWR56_RS01495 b57faa577ebc6891351bb272de69ae55 46 Pfam PF09951 Protein of unknown function (DUF2185) 6 44 8.4E-10 T 29-03-2018 IPR018689 Domain of unknown function DUF2185 CWR56_RS16735 49d825326c64b883bf189f54b6cad946 46 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 7 43 9.8E-10 T 29-03-2018 IPR009229 Staphylococcal AgrD CWR56_RS01475 cb08534f96b8f9f7f6dfcc423f0999e3 251 Pfam PF03609 PTS system sorbose-specific iic component 7 238 2.2E-75 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWR56_RS03115 52363bbd7398b3e23f6e06fdbdefffa3 397 Pfam PF00999 Sodium/hydrogen exchanger family 7 379 1.4E-41 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR56_RS02765 77f824b016951d58abd02b8ec5e3ec07 146 Pfam PF12663 Protein of unknown function (DUF3788) 10 140 1.1E-30 T 29-03-2018 IPR024265 Protein of unknown function DUF3788 CWR56_RS18940 4fe5d2f77d034d9340a5fd8284ddab23 449 Pfam PF03611 PTS system sugar-specific permease component 7 390 3.2E-83 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWR56_RS18940 4fe5d2f77d034d9340a5fd8284ddab23 449 PIRSF PIRSF006304 1 449 1.5E-181 T 29-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 CWR56_RS14145 7175f9e8428f60ec55003351e0b3430f 131 Pfam PF04138 GtrA-like protein 12 129 1.8E-19 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CWR56_RS11010 3e1bd833dd4f43140dfeeba9852b68af 190 Pfam PF12642 Conjugative transposon protein TcpC 2 188 2.3E-43 T 29-03-2018 IPR024735 Conjugative transposon protein TcpC CWR56_RS07290 9fec3e5b57860088ae854817e9aef846 248 SMART SM00382 31 219 3.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07290 9fec3e5b57860088ae854817e9aef846 248 Pfam PF00005 ABC transporter 22 170 6.0E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07290 9fec3e5b57860088ae854817e9aef846 248 SUPERFAMILY SSF52540 3 229 5.6E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07290 9fec3e5b57860088ae854817e9aef846 248 Gene3D G3DSA:3.40.50.300 1 238 6.2E-60 T 29-03-2018 CWR56_RS11185 b24042cef7227014fa3e528d3f1cf466 511 Gene3D G3DSA:2.60.40.1080 213 301 7.7E-4 T 29-03-2018 CWR56_RS11185 b24042cef7227014fa3e528d3f1cf466 511 Gene3D G3DSA:2.60.40.1080 129 212 1.2E-6 T 29-03-2018 CWR56_RS01725 5df0a3496d2113056f2a6c444b7068e5 250 Pfam PF01734 Patatin-like phospholipase 5 106 2.8E-15 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CWR56_RS01725 5df0a3496d2113056f2a6c444b7068e5 250 SUPERFAMILY SSF52151 1 234 9.16E-23 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR56_RS01725 5df0a3496d2113056f2a6c444b7068e5 250 Gene3D G3DSA:3.40.1090.10 1 199 9.2E-17 T 29-03-2018 CWR56_RS03790 b5b00a4279b6d5d644baf7ea805100d9 311 Pfam PF06675 Protein of unknown function (DUF1177) 40 309 5.7E-139 T 29-03-2018 IPR009561 Protein of unknown function DUF1177 CWR56_RS13830 63870089262407e9608b4fca2ca2a9f5 157 Pfam PF12821 Threonine/Serine exporter, ThrE 10 136 6.7E-37 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE CWR56_RS10130 2acc0ba2efb7f372d7a6d5d0a9b7a328 464 Pfam PF00939 Sodium:sulfate symporter transmembrane region 9 461 1.8E-17 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CWR56_RS03245 d038c6b8a7cad124e71ced7781896f60 440 Gene3D G3DSA:1.10.260.40 355 392 0.028 T 29-03-2018 CWR56_RS03245 d038c6b8a7cad124e71ced7781896f60 440 Gene3D G3DSA:1.10.10.10 393 436 0.0026 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS18245 e0e9d5b1a504c968b49f800844268b09 563 Gene3D G3DSA:3.30.40.10 107 321 0.0048 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type CWR56_RS18325 399d5d428ae0fb95d1ed7f5eae9cb664 318 Pfam PF09991 Predicted membrane protein (DUF2232) 15 305 5.8E-71 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 CWR56_RS07775 6b31ba2712a55d6ed17f248126d3a87f 387 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 242 325 1.7E-16 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS07775 6b31ba2712a55d6ed17f248126d3a87f 387 Pfam PF01385 Probable transposase 164 274 6.8E-9 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CWR56_RS07775 6b31ba2712a55d6ed17f248126d3a87f 387 Pfam PF07282 Putative transposase DNA-binding domain 298 363 2.7E-24 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CWR56_RS13150 55e24a495976329da03e9b2b5a756e89 473 Pfam PF02554 Carbon starvation protein CstA 155 282 3.3E-20 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CWR56_RS13150 55e24a495976329da03e9b2b5a756e89 473 Pfam PF02554 Carbon starvation protein CstA 6 143 1.9E-33 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CWR56_RS13150 55e24a495976329da03e9b2b5a756e89 473 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 316 425 3.3E-24 T 29-03-2018 IPR025299 CstA, C-terminal domain CWR56_RS15850 b3ed7e0c2f9a2eed12849072105278e1 275 SUPERFAMILY SSF51219 43 251 8.11E-53 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CWR56_RS15850 b3ed7e0c2f9a2eed12849072105278e1 275 Pfam PF01987 Mitochondrial biogenesis AIM24 51 248 7.4E-40 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWR56_RS15850 b3ed7e0c2f9a2eed12849072105278e1 275 Gene3D G3DSA:3.60.160.10 46 272 2.6E-43 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWR56_RS06355 3b2a23768b05976331652dc97ba5093c 148 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 15 147 4.8E-30 T 29-03-2018 IPR014986 Clostridium phage phiCD119, XkdN CWR56_RS05170 3f0932cb4780e042e541ed9d467f3fd6 197 PIRSF PIRSF006102 1 197 1.1E-71 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CWR56_RS05170 3f0932cb4780e042e541ed9d467f3fd6 197 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 5 194 3.6E-79 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 CWR56_RS05170 3f0932cb4780e042e541ed9d467f3fd6 197 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 196 27.017 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 CWR56_RS05170 3f0932cb4780e042e541ed9d467f3fd6 197 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 185 6.7E-67 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CWR56_RS04975 e8971e89c41e8befc172636100721e49 156 SUPERFAMILY SSF52728 1 156 1.96E-47 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS04975 e8971e89c41e8befc172636100721e49 156 Gene3D G3DSA:3.40.35.10 1 156 2.1E-51 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS04975 e8971e89c41e8befc172636100721e49 156 Pfam PF03830 PTS system sorbose subfamily IIB component 2 148 1.8E-48 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWR56_RS07125 5c0b8d6f2c07b405b6e7c3d07ae87ddf 189 Gene3D G3DSA:3.40.190.10 1 188 2.8E-6 T 29-03-2018 CWR56_RS11065 d7bde02a89a3ed474f500dfe8413b4db 132 Pfam PF12648 TcpE family 6 105 6.1E-32 T 29-03-2018 IPR025608 TcpE family CWR56_RS02205 f2cbdee9a12ed4ed7099dc42de426470 256 TIGRFAM TIGR03732 lanti_perm_MutE: lantibiotic protection ABC transporter permease subunit, MutE/EpiE family 2 256 1.4E-90 T 29-03-2018 IPR021205 Lantibiotic ABC transporter permease subunit, SpaE/MutE CWR56_RS02205 f2cbdee9a12ed4ed7099dc42de426470 256 Pfam PF12730 ABC-2 family transporter protein 4 181 5.1E-14 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS03705 96ecb0ab7eb97045827556af696bc5a6 144 PIRSF PIRSF011474 2 143 1.6E-42 T 29-03-2018 IPR009693 Glucitol operon activator CWR56_RS03705 96ecb0ab7eb97045827556af696bc5a6 144 Pfam PF06923 Glucitol operon activator protein (GutM) 7 112 5.0E-35 T 29-03-2018 IPR009693 Glucitol operon activator CWR56_RS03690 d3780342b30f876aa05c25838ae28250 331 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 321 3.3E-65 T 29-03-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 CWR56_RS03690 d3780342b30f876aa05c25838ae28250 331 Pfam PF01699 Sodium/calcium exchanger protein 186 326 6.6E-26 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CWR56_RS03690 d3780342b30f876aa05c25838ae28250 331 Pfam PF01699 Sodium/calcium exchanger protein 5 143 3.5E-24 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CWR56_RS13400 d4d521db8fe92b814d42ee62bfcf67ce 224 Gene3D G3DSA:1.20.1170.10 18 150 3.1E-4 T 29-03-2018 CWR56_RS13400 d4d521db8fe92b814d42ee62bfcf67ce 224 Pfam PF05949 Bacterial protein of unknown function (DUF881) 85 215 1.3E-36 T 29-03-2018 IPR010273 Protein of unknown function DUF881 CWR56_RS08025 5d1d1f8e6061ea30251bba9b7fd88689 158 Pfam PF12724 Flavodoxin domain 4 140 4.1E-28 T 29-03-2018 IPR026816 Flavodoxin domain CWR56_RS08025 5d1d1f8e6061ea30251bba9b7fd88689 158 SUPERFAMILY SSF52218 1 131 1.29E-18 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS08025 5d1d1f8e6061ea30251bba9b7fd88689 158 Gene3D G3DSA:3.40.50.360 1 136 2.5E-13 T 29-03-2018 IPR029039 Flavoprotein-like domain CWR56_RS12095 5f9e723420677a7f390bb9d7db857db9 168 SUPERFAMILY SSF50475 22 166 1.26E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS12095 5f9e723420677a7f390bb9d7db857db9 168 Gene3D G3DSA:2.30.110.10 3 168 1.8E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR56_RS12095 5f9e723420677a7f390bb9d7db857db9 168 Pfam PF01613 Flavin reductase like domain 25 166 1.2E-5 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CWR56_RS18185 3c939f9d2885387bd73baf5b868d1653 330 Pfam PF00294 pfkB family carbohydrate kinase 2 310 1.6E-30 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CWR56_RS18185 3c939f9d2885387bd73baf5b868d1653 330 SUPERFAMILY SSF53613 1 320 1.56E-53 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS18185 3c939f9d2885387bd73baf5b868d1653 330 Gene3D G3DSA:3.40.1190.20 1 328 2.0E-32 T 29-03-2018 IPR029056 Ribokinase-like CWR56_RS14810 a61cdef03f2d263d229133b954b5be32 172 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 12 167 3.2E-20 T 29-03-2018 IPR013343 CRISPR-associated protein Cas4 CWR56_RS14810 a61cdef03f2d263d229133b954b5be32 172 Pfam PF01930 Domain of unknown function DUF83 11 168 1.1E-51 T 29-03-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 CWR56_RS04195 7ccab7eb1d368b7b45082ed9fcb93df7 328 Gene3D G3DSA:1.10.3720.10 2 306 9.3E-40 T 29-03-2018 CWR56_RS04195 7ccab7eb1d368b7b45082ed9fcb93df7 328 SUPERFAMILY SSF161098 96 305 4.45E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS04195 7ccab7eb1d368b7b45082ed9fcb93df7 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 317 2.0E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS01655 1d1bf6fee7f46b3cbb3acc25261a3fe7 245 Pfam PF12730 ABC-2 family transporter protein 4 182 1.4E-65 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS07095 bed642c6bf0f64e1d6b4efee2f6bceaa 291 Pfam PF00005 ABC transporter 21 157 8.2E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07095 bed642c6bf0f64e1d6b4efee2f6bceaa 291 Gene3D G3DSA:3.40.50.300 1 273 1.3E-39 T 29-03-2018 CWR56_RS07095 bed642c6bf0f64e1d6b4efee2f6bceaa 291 SMART SM00382 29 220 3.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07095 bed642c6bf0f64e1d6b4efee2f6bceaa 291 SUPERFAMILY SSF52540 4 220 5.14E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS11015 1fbfb46947dc0ba6643bf31e4a403aa4 91 Pfam PF16157 Domain of unknown function (DUF4865) 5 77 1.7E-7 T 29-03-2018 IPR032349 Protein of unknown function DUF4865 CWR56_RS11905 4b034ad90fd4948d851db17bb9952d11 303 Pfam PF12642 Conjugative transposon protein TcpC 78 301 2.9E-63 T 29-03-2018 IPR024735 Conjugative transposon protein TcpC CWR56_RS02190 72ef3775be26b61995ce4fe41dc685ba 85 Gene3D G3DSA:3.30.70.790 6 83 6.7E-5 T 29-03-2018 CWR56_RS03830 30c951537c100b57f541cd38bf059b11 294 SUPERFAMILY SSF53187 90 293 1.48E-39 T 29-03-2018 CWR56_RS03830 30c951537c100b57f541cd38bf059b11 294 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 92 290 3.1E-43 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS03830 30c951537c100b57f541cd38bf059b11 294 Gene3D G3DSA:3.40.630.40 71 294 8.4E-47 T 29-03-2018 CWR56_RS03830 30c951537c100b57f541cd38bf059b11 294 SMART SM00646 172 290 1.7E-14 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR56_RS08745 290955dedadad2130b45223de990553f 137 Pfam PF07866 Protein of unknown function (DUF1653) 86 133 2.4E-11 T 29-03-2018 IPR023387 DUF1653-like domain CWR56_RS08745 290955dedadad2130b45223de990553f 137 Gene3D G3DSA:2.30.30.320 86 137 2.1E-15 T 29-03-2018 IPR023387 DUF1653-like domain CWR56_RS08745 290955dedadad2130b45223de990553f 137 Gene3D G3DSA:2.30.30.320 9 85 4.7E-14 T 29-03-2018 IPR023387 DUF1653-like domain CWR56_RS13125 83c75a7625e7294f1bb32f19c9ff56b0 177 SUPERFAMILY SSF53271 6 170 2.36E-44 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS13125 83c75a7625e7294f1bb32f19c9ff56b0 177 Gene3D G3DSA:3.40.50.2020 1 177 8.8E-37 T 29-03-2018 CWR56_RS13125 83c75a7625e7294f1bb32f19c9ff56b0 177 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 38.73 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWR56_RS13125 83c75a7625e7294f1bb32f19c9ff56b0 177 Pfam PF00156 Phosphoribosyl transferase domain 6 150 1.1E-23 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS01790 3b61b97a64a54b2e550eb98219c3cb09 243 Pfam PF03692 Putative zinc- or iron-chelating domain 36 122 1.7E-8 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CWR56_RS11075 bd92d78855e6dda8d489f042b8c82126 167 Pfam PF07275 Antirestriction protein (ArdA) 19 163 1.9E-8 T 29-03-2018 IPR009899 Antirestriction CWR56_RS13655 375e96d0411622e35157d09b60ec05c3 161 Pfam PF07670 Nucleoside recognition 35 130 5.2E-6 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS06400 73d6d8d69af2b6e66306bde76a4136d4 327 Pfam PF12571 Phage tail-collar fibre protein 2 150 6.4E-56 T 29-03-2018 IPR022225 Phage tail fibre protein CWR56_RS06870 78d0631a06539aac78fd0abea613c9fa 158 Gene3D G3DSA:1.10.3210.10 11 157 3.3E-15 T 29-03-2018 CWR56_RS06870 78d0631a06539aac78fd0abea613c9fa 158 Pfam PF01966 HD domain 38 140 2.8E-5 T 29-03-2018 IPR006674 HD domain CWR56_RS06870 78d0631a06539aac78fd0abea613c9fa 158 SUPERFAMILY SSF109604 31 149 4.49E-19 T 29-03-2018 CWR56_RS16835 bcba5421402020d96adb014933cc141c 259 Pfam PF06182 ABC-2 family transporter protein 34 258 7.3E-39 T 29-03-2018 IPR010390 Protein of unknown function DUF990 CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Pfam PF04122 Putative cell wall binding repeat 2 32 119 1.3E-12 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Pfam PF04122 Putative cell wall binding repeat 2 229 313 3.1E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Pfam PF04122 Putative cell wall binding repeat 2 132 220 2.6E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Pfam PF03413 Peptidase propeptide and YPEB domain 409 463 9.9E-4 T 29-03-2018 IPR025711 PepSY domain CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Pfam PF03413 Peptidase propeptide and YPEB domain 337 393 6.0E-7 T 29-03-2018 IPR025711 PepSY domain CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Pfam PF03413 Peptidase propeptide and YPEB domain 490 545 1.8E-7 T 29-03-2018 IPR025711 PepSY domain CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Gene3D G3DSA:3.10.450.40 491 547 3.4E-13 T 29-03-2018 CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Gene3D G3DSA:3.10.450.40 338 394 4.2E-6 T 29-03-2018 CWR56_RS16030 438f910d922155b782152cd0aa97409f 550 Gene3D G3DSA:3.10.450.40 408 464 1.1E-8 T 29-03-2018 CWR56_RS14015 68c5ae2411e80d46e65693d1f8e8f08c 156 Pfam PF14270 Domain of unknown function (DUF4358) 42 139 1.1E-11 T 29-03-2018 IPR025648 Protein of unknown function DUF4358 CWR56_RS02960 def34e08849032a4b129a4e7c8ef0df6 193 Pfam PF12801 4Fe-4S binding domain 28 67 0.0015 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS02960 def34e08849032a4b129a4e7c8ef0df6 193 Pfam PF12801 4Fe-4S binding domain 156 185 0.025 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR56_RS08560 31fb544d5b3b4becda443b1e08f4a967 233 Pfam PF14062 Domain of unknown function (DUF4253) 127 233 3.0E-29 T 29-03-2018 IPR025349 Domain of unknown function DUF4253 CWR56_RS00705 3b7e03ffe254a706593119e263009231 192 Pfam PF12822 ECF transporter, substrate-specific component 5 183 1.3E-29 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CWR56_RS00705 3b7e03ffe254a706593119e263009231 192 PIRSF PIRSF037778 1 192 6.2E-69 T 29-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CWR56_RS06245 893a6c0ae06608e8234da504abf4cdf9 373 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 181 2.6E-31 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CWR56_RS06245 893a6c0ae06608e8234da504abf4cdf9 373 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 219 322 8.7E-10 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR56_RS06245 893a6c0ae06608e8234da504abf4cdf9 373 Gene3D G3DSA:3.40.50.2000 43 195 2.8E-5 T 29-03-2018 CWR56_RS06245 893a6c0ae06608e8234da504abf4cdf9 373 SUPERFAMILY SSF53756 72 370 1.97E-25 T 29-03-2018 CWR56_RS06245 893a6c0ae06608e8234da504abf4cdf9 373 Gene3D G3DSA:3.40.50.2000 196 372 6.6E-16 T 29-03-2018 CWR56_RS17995 fcf5eb19af0774ad55e13d96a1a8ee6d 283 SUPERFAMILY SSF56300 58 280 1.29E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS17995 fcf5eb19af0774ad55e13d96a1a8ee6d 283 Gene3D G3DSA:3.60.21.10 54 276 3.8E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR56_RS17995 fcf5eb19af0774ad55e13d96a1a8ee6d 283 Pfam PF00149 Calcineurin-like phosphoesterase 58 222 2.4E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR56_RS18125 e7b6b26934b74a07b3ac35a827cead3b 423 Pfam PF03611 PTS system sugar-specific permease component 7 402 1.6E-110 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWR56_RS14430 614a0f6bf6ccb9a8a00004b119a7027d 308 SUPERFAMILY SSF56317 6 306 1.7E-78 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS14430 614a0f6bf6ccb9a8a00004b119a7027d 308 Gene3D G3DSA:3.60.110.10 1 307 8.0E-85 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS14430 614a0f6bf6ccb9a8a00004b119a7027d 308 Pfam PF00795 Carbon-nitrogen hydrolase 9 283 7.1E-63 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR56_RS08685 63ec9275b42728a307e7894d4c4cb457 584 Pfam PF04122 Putative cell wall binding repeat 2 231 302 1.5E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS08685 63ec9275b42728a307e7894d4c4cb457 584 Pfam PF04122 Putative cell wall binding repeat 2 141 222 1.2E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS08685 63ec9275b42728a307e7894d4c4cb457 584 Pfam PF04122 Putative cell wall binding repeat 2 43 129 5.6E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS11810 966754d9a8815cd5e9407c845281d4c4 340 Pfam PF01594 AI-2E family transporter 17 333 2.5E-37 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS08775 c85e4fea67d65567cf1d725b4d8fd8bd 384 Pfam PF11449 Putative, 10TM heavy-metal exporter 2 382 2.1E-85 T 29-03-2018 IPR021552 Putative, 10TM heavy-metal exporter CWR56_RS09815 463c369ab4904129588568300a87383e 192 Pfam PF06962 Putative rRNA methylase 52 188 1.6E-53 T 29-03-2018 IPR010719 Putative rRNA methylase CWR56_RS09815 463c369ab4904129588568300a87383e 192 SUPERFAMILY SSF53335 22 146 3.0E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR56_RS09815 463c369ab4904129588568300a87383e 192 Gene3D G3DSA:3.40.50.150 4 192 4.6E-26 T 29-03-2018 CWR56_RS04180 1c25f6e6171026b1ec68b597a2db47a2 74 Pfam PF01106 NifU-like domain 5 71 2.4E-26 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CWR56_RS04180 1c25f6e6171026b1ec68b597a2db47a2 74 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 17 71 4.0E-14 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CWR56_RS04180 1c25f6e6171026b1ec68b597a2db47a2 74 Gene3D G3DSA:3.30.300.130 1 74 1.3E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CWR56_RS04180 1c25f6e6171026b1ec68b597a2db47a2 74 SUPERFAMILY SSF117916 2 73 6.28E-25 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CWR56_RS04935 f8f6c45920f40155d131452178f81d18 443 PIRSF PIRSF038958 7 443 1.4E-82 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CWR56_RS04935 f8f6c45920f40155d131452178f81d18 443 Pfam PF01943 Polysaccharide biosynthesis protein 12 305 7.0E-25 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CWR56_RS12795 c426538fbf570c40647171aaaff4db49 174 Pfam PF07155 ECF-type riboflavin transporter, S component 8 171 1.3E-49 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CWR56_RS17320 21b1eb659c805c21f506cb292a4c371b 128 Pfam PF03899 ATP synthase I chain 18 108 1.3E-11 T 29-03-2018 IPR005598 ATP synthase protein I CWR56_RS02410 0f5975dd452b5a95708dffeb11329f23 513 Pfam PF03806 AbgT putative transporter family 14 510 6.7E-182 T 29-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 CWR56_RS03100 8855ca312a4ebc3b5fa6212d86450f70 212 Pfam PF13346 ABC-2 family transporter protein 4 206 6.8E-31 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CWR56_RS08960 8ac0ad1d2d2cc7eea9d51a754fa90a3b 190 Pfam PF09084 NMT1/THI5 like 54 170 6.4E-12 T 29-03-2018 IPR015168 SsuA/THI5-like CWR56_RS08960 8ac0ad1d2d2cc7eea9d51a754fa90a3b 190 Gene3D G3DSA:3.40.190.10 1 189 1.2E-11 T 29-03-2018 CWR56_RS08960 8ac0ad1d2d2cc7eea9d51a754fa90a3b 190 SUPERFAMILY SSF53850 40 172 1.12E-19 T 29-03-2018 CWR56_RS17760 7d81e95ba58c40e43cbadce12e596ff3 322 SUPERFAMILY SSF56266 2 318 1.8E-66 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS17760 7d81e95ba58c40e43cbadce12e596ff3 322 Pfam PF03576 Peptidase family S58 3 308 9.6E-51 T 29-03-2018 IPR005321 Peptidase S58, DmpA CWR56_RS17760 7d81e95ba58c40e43cbadce12e596ff3 322 Gene3D G3DSA:3.60.70.12 1 320 3.8E-100 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CWR56_RS11140 cc80ab123ecdd7768e01113370926809 139 Pfam PF06125 Bacterial protein of unknown function (DUF961) 7 107 2.5E-37 T 29-03-2018 IPR010365 Protein of unknown function DUF961 CWR56_RS14595 aeb91e262dd57e8734f33c4aa0271229 387 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 2 383 1.5E-146 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CWR56_RS08245 49b82865ba9a8b08818a1e59de1f2fb3 254 Pfam PF01553 Acyltransferase 56 186 2.5E-20 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWR56_RS08245 49b82865ba9a8b08818a1e59de1f2fb3 254 SUPERFAMILY SSF69593 45 243 9.15E-26 T 29-03-2018 CWR56_RS08245 49b82865ba9a8b08818a1e59de1f2fb3 254 Gene3D G3DSA:3.40.1130.10 22 252 5.5E-34 T 29-03-2018 CWR56_RS08245 49b82865ba9a8b08818a1e59de1f2fb3 254 SMART SM00563 69 189 8.2E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWR56_RS11045 a0d7faaa21b3f14d71c83d98ead54896 300 Pfam PF12642 Conjugative transposon protein TcpC 75 298 5.0E-60 T 29-03-2018 IPR024735 Conjugative transposon protein TcpC CWR56_RS14725 c2ff7e3fa64b581e879048d003f616d2 641 Pfam PF01496 V-type ATPase 116kDa subunit family 175 392 1.9E-12 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS14725 c2ff7e3fa64b581e879048d003f616d2 641 Pfam PF01496 V-type ATPase 116kDa subunit family 570 629 2.0E-9 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CWR56_RS02315 360a2ec89d62f69c8d5bc6336c68658a 439 Gene3D G3DSA:1.10.287.130 229 290 3.4E-7 T 29-03-2018 CWR56_RS02315 360a2ec89d62f69c8d5bc6336c68658a 439 Gene3D G3DSA:3.30.565.10 291 439 3.8E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02315 360a2ec89d62f69c8d5bc6336c68658a 439 SUPERFAMILY SSF55874 331 436 7.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR56_RS02315 360a2ec89d62f69c8d5bc6336c68658a 439 Pfam PF14501 GHKL domain 330 435 1.9E-22 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR56_RS09375 3088221e95be11c560a1fbf0946d0047 228 Pfam PF04474 Protein of unknown function (DUF554) 3 222 6.9E-76 T 29-03-2018 IPR007563 Protein of unknown function DUF554 CWR56_RS04805 06ed754b221ad1f6a686bcde2ef54873 350 Pfam PF04122 Putative cell wall binding repeat 2 152 242 9.9E-11 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04805 06ed754b221ad1f6a686bcde2ef54873 350 Pfam PF04122 Putative cell wall binding repeat 2 54 139 1.0E-16 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS04805 06ed754b221ad1f6a686bcde2ef54873 350 Pfam PF04122 Putative cell wall binding repeat 2 251 340 6.0E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS17855 382c8998d8f908761d7233ba93abbb54 464 Pfam PF00474 Sodium:solute symporter family 34 417 3.2E-25 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS05580 e12ca564f5fb9b6ac72dd108aad22b87 201 Pfam PF01944 Stage II sporulation protein M 22 180 4.3E-7 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CWR56_RS09830 b5171b63a2740e2b652c1a42a63f48dc 219 Gene3D G3DSA:1.25.40.10 21 134 4.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS09830 b5171b63a2740e2b652c1a42a63f48dc 219 SUPERFAMILY SSF48452 22 107 8.35E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 Pfam PF03600 Citrate transporter 17 364 1.9E-52 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 PRINTS PR00758 Arsenical pump membrane protein signature 274 298 2.4E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 PRINTS PR00758 Arsenical pump membrane protein signature 360 385 2.4E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 PRINTS PR00758 Arsenical pump membrane protein signature 393 417 2.4E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 2.4E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 PRINTS PR00758 Arsenical pump membrane protein signature 319 341 2.4E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR56_RS08105 8f824ed0cb6db4a24f4c01bbd6337879 421 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 2.4E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR56_RS11325 593333850e569bedb658ea5f9c65abeb 412 Pfam PF05569 BlaR1 peptidase M56 69 277 1.5E-38 T 29-03-2018 IPR008756 Peptidase M56 CWR56_RS01885 91974b9e2b0dfe3faf13ec96044f4e0a 399 Gene3D G3DSA:3.40.50.10540 1 399 2.4E-104 T 29-03-2018 IPR023606 CoA-transferase family III domain CWR56_RS01885 91974b9e2b0dfe3faf13ec96044f4e0a 399 Pfam PF02515 CoA-transferase family III 3 374 2.1E-91 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CWR56_RS01885 91974b9e2b0dfe3faf13ec96044f4e0a 399 SUPERFAMILY SSF89796 2 397 7.33E-101 T 29-03-2018 IPR023606 CoA-transferase family III domain CWR56_RS06555 68ff51d65cb3dcedad0ada84619da2ef 243 Gene3D G3DSA:3.20.20.190 1 243 3.5E-70 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR56_RS06555 68ff51d65cb3dcedad0ada84619da2ef 243 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 231 8.5E-42 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWR56_RS06555 68ff51d65cb3dcedad0ada84619da2ef 243 SUPERFAMILY SSF51695 3 237 1.15E-72 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR56_RS13725 9cbfccf530e9aa569bedc38e01d84fcd 279 Pfam PF12686 Protein of unknown function (DUF3800) 11 249 1.5E-31 T 29-03-2018 IPR024524 Protein of unknown function DUF3800 CWR56_RS15025 4225c819dbc07e1e43b02ecbc5f17c53 371 Pfam PF02378 Phosphotransferase system, EIIC 21 296 5.8E-13 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15025 4225c819dbc07e1e43b02ecbc5f17c53 371 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 8 346 2.0E-81 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR56_RS05465 a12ce74185226ad50c12d5f9440dcc47 184 Gene3D G3DSA:3.30.429.10 48 178 2.5E-4 T 29-03-2018 CWR56_RS07105 9361249337d2c2fe409ffb81c8b4a364 441 Pfam PF01554 MatE 20 181 1.9E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07105 9361249337d2c2fe409ffb81c8b4a364 441 Pfam PF01554 MatE 248 399 8.0E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07105 9361249337d2c2fe409ffb81c8b4a364 441 PIRSF PIRSF006603 2 441 5.0E-71 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07105 9361249337d2c2fe409ffb81c8b4a364 441 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 414 1.0E-60 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWR56_RS07885 9f844ba7dfd4e6ebe0788f9112f9cd1d 576 Pfam PF03553 Na+/H+ antiporter family 200 533 1.1E-63 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR56_RS12005 8966470f0eed59d0ccdb21d29bc0c97e 191 SUPERFAMILY SSF53323 1 190 2.75E-41 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CWR56_RS12005 8966470f0eed59d0ccdb21d29bc0c97e 191 Gene3D G3DSA:3.40.920.10 1 191 3.1E-48 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS12005 8966470f0eed59d0ccdb21d29bc0c97e 191 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 187 1.5E-37 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR56_RS08980 7f5cd4f1b2f47b1b81b05cfefd1c49b2 127 Pfam PF12732 YtxH-like protein 28 98 1.7E-16 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH CWR56_RS17965 28e0e1c3d313da776bca8fc019a0fae1 241 PIRSF PIRSF037984 1 232 5.6E-83 T 29-03-2018 IPR017342 S-adenosyl-L-methionine dependent methionine synthase, predicted CWR56_RS17965 28e0e1c3d313da776bca8fc019a0fae1 241 SUPERFAMILY SSF56507 18 201 1.83E-26 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17965 28e0e1c3d313da776bca8fc019a0fae1 241 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 138 199 6.0E-7 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS17965 28e0e1c3d313da776bca8fc019a0fae1 241 Gene3D G3DSA:3.10.196.10 86 237 9.6E-21 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR56_RS10695 70650ef2d0ebae3d23d20fe8bf46c680 188 Pfam PF00484 Carbonic anhydrase 34 177 2.5E-16 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR56_RS10695 70650ef2d0ebae3d23d20fe8bf46c680 188 SUPERFAMILY SSF53056 2 181 1.44E-40 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR56_RS10695 70650ef2d0ebae3d23d20fe8bf46c680 188 Gene3D G3DSA:3.40.1050.10 1 188 4.3E-34 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR56_RS10695 70650ef2d0ebae3d23d20fe8bf46c680 188 SMART SM00947 26 182 4.3E-36 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR56_RS03050 089007f34b7948f981fb33f664880841 226 Pfam PF12730 ABC-2 family transporter protein 4 183 1.2E-8 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CWR56_RS03575 467cb721ad0255cbeb3e27744ab9e323 293 Pfam PF14133 Domain of unknown function (DUF4300) 37 292 1.0E-88 T 29-03-2018 IPR025389 Protein of unknown function DUF4300 CWR56_RS03575 467cb721ad0255cbeb3e27744ab9e323 293 Gene3D G3DSA:1.10.260.40 33 127 0.0065 T 29-03-2018 CWR56_RS02330 347b008e2ecf2a4cd04e1520b165c64a 848 Pfam PF02687 FtsX-like permease family 742 838 4.1E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS02330 347b008e2ecf2a4cd04e1520b165c64a 848 Pfam PF02687 FtsX-like permease family 293 379 8.0E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS09155 037ee87f2f2c0fd9981f753f4e62f8f6 512 Pfam PF03806 AbgT putative transporter family 16 510 6.8E-147 T 29-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 CWR56_RS11020 aafbb357b5c5007065a2cda1d6469f5e 168 Pfam PF04892 VanZ like family 13 131 7.3E-19 T 29-03-2018 IPR006976 VanZ-like CWR56_RS09030 f51c6621e1f380f0058b38ce5b4149cf 266 Gene3D G3DSA:1.10.3720.10 23 266 9.4E-21 T 29-03-2018 CWR56_RS09030 f51c6621e1f380f0058b38ce5b4149cf 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 266 6.3E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS09030 f51c6621e1f380f0058b38ce5b4149cf 266 SUPERFAMILY SSF161098 70 251 9.94E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR56_RS07855 bb25f3645e5e4c7571b5763ed0bc67f5 251 SUPERFAMILY SSF52540 1 226 7.92E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR56_RS07855 bb25f3645e5e4c7571b5763ed0bc67f5 251 SMART SM00382 26 213 2.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CWR56_RS07855 bb25f3645e5e4c7571b5763ed0bc67f5 251 Pfam PF00005 ABC transporter 18 164 7.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR56_RS07855 bb25f3645e5e4c7571b5763ed0bc67f5 251 Gene3D G3DSA:3.40.50.300 1 238 9.2E-61 T 29-03-2018 CWR56_RS14950 14bf320f71182080f994ed6fb734b9f5 281 Pfam PF02687 FtsX-like permease family 89 184 4.1E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS13405 ff2c0129dc1ab1057b54705ce3b87a72 232 Gene3D G3DSA:1.20.5.400 37 124 3.2E-5 T 29-03-2018 CWR56_RS13405 ff2c0129dc1ab1057b54705ce3b87a72 232 Pfam PF05949 Bacterial protein of unknown function (DUF881) 87 222 6.1E-33 T 29-03-2018 IPR010273 Protein of unknown function DUF881 CWR56_RS01760 a1b2fb1bb028e5ba65be2b5219f76b1c 858 Pfam PF12704 MacB-like periplasmic core domain 19 187 7.8E-7 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CWR56_RS01760 a1b2fb1bb028e5ba65be2b5219f76b1c 858 Pfam PF02687 FtsX-like permease family 270 367 1.5E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS01760 a1b2fb1bb028e5ba65be2b5219f76b1c 858 Pfam PF02687 FtsX-like permease family 758 849 9.1E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS00755 c45cf5127363fca168b74fce73525b21 267 Pfam PF02517 CAAX protease self-immunity 130 225 2.9E-12 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR56_RS11335 bbabecfc31e0838e47c888f7aee51efb 233 Pfam PF03591 AzlC protein 16 155 2.9E-36 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CWR56_RS12490 013e986b97443b76ad4feffe81033926 258 Gene3D G3DSA:3.40.50.1820 1 258 2.6E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS12490 013e986b97443b76ad4feffe81033926 258 SUPERFAMILY SSF53474 3 256 8.11E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR56_RS12490 013e986b97443b76ad4feffe81033926 258 Pfam PF12146 Serine aminopeptidase, S33 9 238 2.6E-10 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CWR56_RS07135 6655cd39068dadafb5238c48480e97eb 304 SUPERFAMILY SSF158430 190 303 7.06E-36 T 29-03-2018 CWR56_RS07135 6655cd39068dadafb5238c48480e97eb 304 SUPERFAMILY SSF158430 2 68 1.96E-33 T 29-03-2018 CWR56_RS07135 6655cd39068dadafb5238c48480e97eb 304 SUPERFAMILY SSF158430 122 176 1.96E-33 T 29-03-2018 CWR56_RS07135 6655cd39068dadafb5238c48480e97eb 304 Pfam PF11155 Domain of unknown function (DUF2935) 11 175 1.8E-41 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CWR56_RS07135 6655cd39068dadafb5238c48480e97eb 304 Pfam PF11155 Domain of unknown function (DUF2935) 191 299 8.0E-31 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CWR56_RS17625 c40751ce834a3a4ed2d13a7993c5f81b 289 PIRSF PIRSF011468 1 282 5.9E-136 T 29-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS17625 c40751ce834a3a4ed2d13a7993c5f81b 289 Pfam PF06007 Phosphonate metabolism protein PhnJ 3 273 1.2E-143 T 29-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR56_RS14075 a2200699a616bebdb0e73972f8b9bc9c 396 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 30 392 1.6E-46 T 29-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CWR56_RS14075 a2200699a616bebdb0e73972f8b9bc9c 396 SUPERFAMILY SSF53756 126 394 3.45E-11 T 29-03-2018 CWR56_RS02920 0a8ba32498943366e2f26b0a35ddf292 76 Pfam PF11148 Protein of unknown function (DUF2922) 5 70 1.3E-24 T 29-03-2018 IPR021321 Protein of unknown function DUF2922 CWR56_RS10925 d30ec14fdaf7c7701f3f432886088655 63 Pfam PF13783 Domain of unknown function (DUF4177) 4 62 1.5E-6 T 29-03-2018 IPR025234 Protein of unknown function DUF4177 CWR56_RS07545 50abbd3e1c20e0a8f34b42d361c59ae7 25 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 2 25 2.1E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CWR56_RS07545 50abbd3e1c20e0a8f34b42d361c59ae7 25 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 2 25 2.0E-11 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CWR56_RS01305 eb83c559e9e7c44f55f2955aa3db6bd2 67 Pfam PF06289 Flagellar protein (FlbD) 1 58 3.3E-23 T 29-03-2018 IPR009384 Flagellar CWR56_RS09390 f03d131b360bb7101e5757e60791f314 359 Gene3D G3DSA:3.40.50.1220 1 325 1.8E-4 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS09390 f03d131b360bb7101e5757e60791f314 359 Pfam PF13289 SIR2-like domain 144 324 8.1E-8 T 29-03-2018 CWR56_RS09390 f03d131b360bb7101e5757e60791f314 359 SUPERFAMILY SSF52467 2 34 5.61E-11 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS09390 f03d131b360bb7101e5757e60791f314 359 SUPERFAMILY SSF52467 190 307 5.61E-11 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS09390 f03d131b360bb7101e5757e60791f314 359 SUPERFAMILY SSF52467 93 157 5.61E-11 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR56_RS13840 995790863307314f295ddb222ff4c748 97 Pfam PF02583 Metal-sensitive transcriptional repressor 11 94 8.5E-32 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CWR56_RS03560 378b4f4e7fb145d17848e50aebc13344 138 Pfam PF12953 Domain of unknown function (DUF3842) 3 130 3.8E-50 T 29-03-2018 IPR024208 Protein of unknown function DUF3842 CWR56_RS17900 96d5402b79f82a7173ecd031f6c5c58e 848 Pfam PF12704 MacB-like periplasmic core domain 19 204 2.5E-9 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CWR56_RS17900 96d5402b79f82a7173ecd031f6c5c58e 848 Pfam PF02687 FtsX-like permease family 748 838 3.5E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS17900 96d5402b79f82a7173ecd031f6c5c58e 848 Pfam PF02687 FtsX-like permease family 301 397 6.8E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS15195 253bbb39e1db2cade1cffec0f4ad8a66 448 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 18 441 1.7E-112 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR56_RS15195 253bbb39e1db2cade1cffec0f4ad8a66 448 Pfam PF02378 Phosphotransferase system, EIIC 30 367 1.5E-51 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS15195 253bbb39e1db2cade1cffec0f4ad8a66 448 PIRSF PIRSF006351 2 447 6.8E-149 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR56_RS13920 4aeff6845efc2add837a9a65a9c81cc6 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 39.673 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CWR56_RS13920 4aeff6845efc2add837a9a65a9c81cc6 170 Gene3D G3DSA:3.40.50.2020 1 169 6.1E-43 T 29-03-2018 CWR56_RS13920 4aeff6845efc2add837a9a65a9c81cc6 170 SUPERFAMILY SSF53271 2 167 5.25E-54 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CWR56_RS13920 4aeff6845efc2add837a9a65a9c81cc6 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 1.4E-71 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CWR56_RS13920 4aeff6845efc2add837a9a65a9c81cc6 170 Pfam PF00156 Phosphoribosyl transferase domain 27 147 1.3E-17 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR56_RS09950 e19dd8deb90a10edb3944c640cbeea39 452 Pfam PF00860 Permease family 19 401 2.5E-65 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR56_RS08600 93e18b62d1d689891dec014f660140f8 348 Pfam PF16169 Domain of unknown function (DUF4872) 163 249 5.1E-8 T 29-03-2018 IPR032369 Domain of unknown function DUF4872 CWR56_RS08600 93e18b62d1d689891dec014f660140f8 348 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 15 150 2.2E-31 T 29-03-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 CWR56_RS08600 93e18b62d1d689891dec014f660140f8 348 Gene3D G3DSA:3.90.70.10 21 199 8.4E-6 T 29-03-2018 CWR56_RS05570 dad7f1dcdc5fc657f76ddfd5b0fd9353 355 Pfam PF12982 Protein of unknown function (DUF3866) 32 349 9.9E-135 T 29-03-2018 IPR024479 Protein of unknown function DUF3866 CWR56_RS12035 4e571239d4da3d4ab497649e006b128b 139 Pfam PF12653 Protein of unknown function (DUF3785) 4 139 6.0E-63 T 29-03-2018 IPR024210 Protein of unknown function DUF3785 CWR56_RS17500 ef02bffaf44a4ec0ed8bfcac0bf557a3 302 Pfam PF04350 Pilus assembly protein, PilO 53 170 8.8E-5 T 29-03-2018 IPR007445 Pilus assembly protein, PilO CWR56_RS17500 ef02bffaf44a4ec0ed8bfcac0bf557a3 302 Gene3D G3DSA:3.30.70.60 98 212 8.6E-10 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CWR56_RS11000 f5b83ab80dd00e58af4d28fd84690985 158 Gene3D G3DSA:2.40.30.70 6 141 6.0E-37 T 29-03-2018 IPR023370 TsaA-like domain CWR56_RS11000 f5b83ab80dd00e58af4d28fd84690985 158 SUPERFAMILY SSF118196 2 157 2.09E-46 T 29-03-2018 IPR023370 TsaA-like domain CWR56_RS11000 f5b83ab80dd00e58af4d28fd84690985 158 Pfam PF01980 Uncharacterised protein family UPF0066 16 126 1.9E-32 T 29-03-2018 IPR023370 TsaA-like domain CWR56_RS11225 f3569ab0c417c743b58849bcb8c14a5f 345 Gene3D G3DSA:1.10.10.10 142 224 0.0066 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS11225 f3569ab0c417c743b58849bcb8c14a5f 345 Gene3D G3DSA:1.10.10.10 276 341 2.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR56_RS07295 296e0b0b2d1e3eb4b970030c0f5a1df0 626 Pfam PF02687 FtsX-like permease family 87 180 9.6E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS07295 296e0b0b2d1e3eb4b970030c0f5a1df0 626 PIRSF PIRSF018968 1 626 1.4E-249 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR56_RS05825 4d444599b0568ec7f23e9696a76b263e 430 Pfam PF05525 Branched-chain amino acid transport protein 4 420 2.9E-115 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR56_RS05825 4d444599b0568ec7f23e9696a76b263e 430 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 11 407 4.5E-98 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR56_RS13885 df6e640f4d441f1b974266fd289e0e99 410 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 400 1.6E-25 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CWR56_RS02925 e0d92a23dad3d4f23109d97c626eff42 73 Pfam PF07872 Protein of unknown function (DUF1659) 10 51 1.7E-16 T 29-03-2018 IPR012454 Protein of unknown function DUF1659 CWR56_RS06995 b8603de2b736d2eeb7ff7381d2a821c8 198 Pfam PF12672 Protein of unknown function (DUF3793) 25 188 5.0E-38 T 29-03-2018 IPR024523 Protein of unknown function DUF3793 CWR56_RS02235 f58afa1ce89896a2742220d8e6ae5be3 157 Pfam PF01066 CDP-alcohol phosphatidyltransferase 8 47 2.7E-8 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWR56_RS02235 f58afa1ce89896a2742220d8e6ae5be3 157 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 25 47 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWR56_RS10650 a7b1e71bd27901606d2dd60f17094c13 388 Gene3D G3DSA:1.10.287.70 1 379 0.0025 T 29-03-2018 CWR56_RS10650 a7b1e71bd27901606d2dd60f17094c13 388 Pfam PF01594 AI-2E family transporter 37 370 5.7E-49 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS12920 3147bc3734321eac83310a43c3647b7a 174 Gene3D G3DSA:1.20.120.20 9 165 6.5E-5 T 29-03-2018 CWR56_RS02815 133effa2a81eca97b298de80080d6a0f 82 Gene3D G3DSA:1.20.5.320 1 82 0.001 T 29-03-2018 CWR56_RS13380 3c39994d58558c5746b3bf83180d66ae 281 PIRSF PIRSF018571 1 280 1.7E-46 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CWR56_RS13380 3c39994d58558c5746b3bf83180d66ae 281 Pfam PF03419 Sporulation factor SpoIIGA 2 277 8.7E-61 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CWR56_RS01275 20d7ae8b134b4127c5026682f4efe571 243 Pfam PF02108 Flagellar assembly protein FliH 111 226 1.6E-6 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CWR56_RS09675 827bb2d859c8b8fdb074005543fb1715 212 Pfam PF13346 ABC-2 family transporter protein 3 207 1.1E-42 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CWR56_RS15450 db7723b95df9b887449cf0b85f09bbc7 245 Gene3D G3DSA:3.40.50.880 3 245 2.4E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS15450 db7723b95df9b887449cf0b85f09bbc7 245 Pfam PF07722 Peptidase C26 7 223 4.4E-67 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CWR56_RS15450 db7723b95df9b887449cf0b85f09bbc7 245 SUPERFAMILY SSF52317 32 242 3.36E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR56_RS10990 2a2bb6b9e9ce523062f80205ce5a0736 389 Pfam PF02371 Transposase IS116/IS110/IS902 family 267 349 1.4E-22 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWR56_RS10990 2a2bb6b9e9ce523062f80205ce5a0736 389 Pfam PF01548 Transposase 4 159 1.6E-37 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWR56_RS07520 ba2431fb38106185a44066314513e8cc 394 Gene3D G3DSA:3.20.20.80 17 378 4.1E-9 T 29-03-2018 CWR56_RS09885 396dfb07f2b211df392507f05de6041f 332 Pfam PF13170 Protein of unknown function (DUF4003) 16 315 6.5E-101 T 29-03-2018 IPR025062 Protein of unknown function DUF4003 CWR56_RS08270 6b99bc76512e26fa61caf29e3574ec00 107 Gene3D G3DSA:3.30.450.30 1 107 7.6E-4 T 29-03-2018 CWR56_RS06295 e6815a646141b8f74e1bd3536b0b032f 384 Gene3D G3DSA:3.90.1720.10 213 381 8.3E-11 T 29-03-2018 CWR56_RS06295 e6815a646141b8f74e1bd3536b0b032f 384 Pfam PF12671 Putative amidase domain 220 380 2.7E-46 T 29-03-2018 IPR024301 Putative amidase domain CWR56_RS01200 e407ca859e5bb37f2392efd7df5c757c 111 Pfam PF05400 Flagellar protein FliT 19 96 9.8E-7 T 29-03-2018 IPR008622 Flagellar protein FliT CWR56_RS13235 7eae34ec2b3a49abef777ecb8cba83e1 175 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 2 35 8.2E-15 T 29-03-2018 IPR019933 DivIVA domain CWR56_RS13235 7eae34ec2b3a49abef777ecb8cba83e1 175 Pfam PF05103 DivIVA protein 2 132 2.0E-44 T 29-03-2018 IPR007793 DivIVA family CWR56_RS02225 71a13a99b391bd63f8ba9b37f11af641 822 Pfam PF02687 FtsX-like permease family 302 397 1.0E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS02225 71a13a99b391bd63f8ba9b37f11af641 822 Pfam PF02687 FtsX-like permease family 724 813 7.8E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS17710 57be75377d79ddd853b67a8b18812afb 63 Pfam PF04070 Domain of unknown function (DUF378) 2 57 1.0E-22 T 29-03-2018 IPR007211 Protein of unknown function DUF378 CWR56_RS11985 412cfd1efad86a8581738967471a1ec3 108 Pfam PF06125 Bacterial protein of unknown function (DUF961) 4 103 5.8E-34 T 29-03-2018 IPR010365 Protein of unknown function DUF961 CWR56_RS12405 611d80a1e7d616a30689ddad7fefd59b 245 Pfam PF01881 CRISPR associated protein Cas6 98 243 1.9E-26 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CWR56_RS12405 611d80a1e7d616a30689ddad7fefd59b 245 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 235 2.8E-23 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CWR56_RS18470 f56cf8051a63307830dd6e3b30619e32 98 Pfam PF12732 YtxH-like protein 13 70 2.4E-15 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH CWR56_RS12065 164d88bf5208177d473f8226a54d11a3 160 Pfam PF11188 Protein of unknown function (DUF2975) 47 160 5.8E-10 T 29-03-2018 IPR021354 Protein of unknown function DUF2975 CWR56_RS01680 f4180994bc943a889c4748facf2a27a4 62 Gene3D G3DSA:1.10.1660.20 1 47 2.1E-5 T 29-03-2018 CWR56_RS06390 d2615ce140436f4ded730bfe653ac022 350 Pfam PF04865 Baseplate J-like protein 62 300 1.6E-69 T 29-03-2018 IPR006949 Baseplate protein J-like CWR56_RS19010 8c9831b359c4d8f1dce89ff6cff92b87 175 Pfam PF05991 YacP-like NYN domain 9 173 4.6E-55 T 29-03-2018 IPR010298 Protein of unknown function DUF901 CWR56_RS17875 fe5aae8fa3735c46d43e290cf935f456 75 Pfam PF07205 Domain of unknown function (DUF1413) 6 74 3.7E-27 T 29-03-2018 IPR010813 Protein of unknown function DUF1413 CWR56_RS17365 047fe6388b58d85652eb2b63315e056c 226 Pfam PF02535 ZIP Zinc transporter 86 223 3.1E-16 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR56_RS10090 4a2215b76ec790d12253bd91ea9073bd 422 Pfam PF00999 Sodium/hydrogen exchanger family 16 403 3.0E-50 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR56_RS11925 53beb21c9c7aa6d3eddc8a4e7ce4ae3f 132 Pfam PF12648 TcpE family 6 105 1.5E-32 T 29-03-2018 IPR025608 TcpE family CWR56_RS11055 ba74f9825ab4052a3c502d9a5649cb0f 731 Gene3D G3DSA:1.10.287.700 120 615 2.3E-7 T 29-03-2018 CWR56_RS17790 34cc904ba03adea037e326d249a816d5 168 Pfam PF07486 Cell Wall Hydrolase 69 166 2.1E-29 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CWR56_RS16840 155bc6ad2c176e53a50f2db49425088e 272 Pfam PF06182 ABC-2 family transporter protein 41 262 2.6E-21 T 29-03-2018 IPR010390 Protein of unknown function DUF990 CWR56_RS06905 b0b079da12fd64c0c1ed2017424b0bd7 853 Pfam PF02687 FtsX-like permease family 307 405 9.9E-14 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS06905 b0b079da12fd64c0c1ed2017424b0bd7 853 Pfam PF02687 FtsX-like permease family 752 843 4.9E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS06905 b0b079da12fd64c0c1ed2017424b0bd7 853 Pfam PF12704 MacB-like periplasmic core domain 19 237 1.9E-8 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CWR56_RS10105 1223e548dd5a6fdadde6f20dc17cf4de 531 Pfam PF16949 Putative ATP-binding cassette 43 485 2.3E-8 T 29-03-2018 IPR031599 Putative ATP-binding cassette CWR56_RS10885 b09cb7c486c475f5e2f106089ea1aad1 398 Pfam PF05762 VWA domain containing CoxE-like protein 183 274 5.0E-8 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like CWR56_RS02015 88c7a7dc8772df8bb1f7647a37d7a51d 386 Pfam PF04122 Putative cell wall binding repeat 2 33 115 2.4E-13 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS02015 88c7a7dc8772df8bb1f7647a37d7a51d 386 Pfam PF04122 Putative cell wall binding repeat 2 218 288 2.1E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS02015 88c7a7dc8772df8bb1f7647a37d7a51d 386 Pfam PF04122 Putative cell wall binding repeat 2 128 209 1.6E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS13335 31fb323a8d5e9a43b1c0946697354fac 310 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 4 288 6.0E-48 T 29-03-2018 CWR56_RS13335 31fb323a8d5e9a43b1c0946697354fac 310 Pfam PF14045 YIEGIA protein 5 297 9.0E-107 T 29-03-2018 IPR025918 YIEGIA protein CWR56_RS11805 14d85559abc81a9a36fefef0c906d5bd 102 Pfam PF07561 Domain of Unknown Function (DUF1540) 7 44 1.5E-8 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CWR56_RS11805 14d85559abc81a9a36fefef0c906d5bd 102 Pfam PF07561 Domain of Unknown Function (DUF1540) 67 99 5.7E-6 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CWR56_RS01290 c48eff1d5699544810e96dcba821f591 401 Pfam PF02120 Flagellar hook-length control protein FliK 267 348 8.5E-16 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CWR56_RS13185 bdc2d18a462b981027a22787e3f64a12 94 Gene3D G3DSA:2.60.120.260 1 47 6.7E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like CWR56_RS18110 9ab881cb178d167c500fe817b311b697 210 Pfam PF01081 KDPG and KHG aldolase 7 189 9.4E-33 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CWR56_RS18110 9ab881cb178d167c500fe817b311b697 210 SUPERFAMILY SSF51569 2 203 1.06E-53 T 29-03-2018 CWR56_RS18110 9ab881cb178d167c500fe817b311b697 210 Gene3D G3DSA:3.20.20.70 4 210 1.9E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS17795 14f9eec5b0830d2dd2f6da17d427c56a 219 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 42 167 5.5E-52 T 29-03-2018 IPR014202 Sporulation stage II, protein R CWR56_RS17795 14f9eec5b0830d2dd2f6da17d427c56a 219 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 11 171 3.9E-61 T 29-03-2018 IPR014202 Sporulation stage II, protein R CWR56_RS03490 a6a86f34c15eaae69e4643ac60826d1f 224 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 110 204 2.3E-37 T 29-03-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal CWR56_RS08395 967bbbff0a5e01f72d36107280416b10 383 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 37 383 4.2E-80 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit CWR56_RS01285 5ea237691f004627beb01ecf4292916e 146 Pfam PF02050 Flagellar FliJ protein 21 139 9.3E-23 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CWR56_RS01285 5ea237691f004627beb01ecf4292916e 146 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 140 2.4E-24 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CWR56_RS09305 1173db4221be81243b7ce906186df33d 851 Pfam PF02687 FtsX-like permease family 750 843 2.5E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS09305 1173db4221be81243b7ce906186df33d 851 Pfam PF02687 FtsX-like permease family 281 373 1.9E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS17660 4b0c464f4983c6fb69a259988cbffbdd 194 Pfam PF07670 Nucleoside recognition 45 150 2.0E-10 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR56_RS17380 b4d33a3102d6a83d83020617595d14d5 297 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 53 293 3.0E-62 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CWR56_RS17380 b4d33a3102d6a83d83020617595d14d5 297 Pfam PF07136 Protein of unknown function (DUF1385) 53 296 2.8E-91 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CWR56_RS14540 415e9b8125ed6124bf640716dea7fb34 231 Pfam PF16481 Domain of unknown function (DUF5058) 8 225 6.6E-76 T 29-03-2018 IPR032479 Protein of unknown function DUF5058 CWR56_RS05035 0816f21cd67654ddf592bdbfdfa5a02b 186 Pfam PF11193 Protein of unknown function (DUF2812) 18 132 4.1E-24 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 CWR56_RS13670 d551b71f61f6df0b3974a5b7eb80f26a 395 Gene3D G3DSA:3.20.20.70 28 346 4.4E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR56_RS13670 d551b71f61f6df0b3974a5b7eb80f26a 395 SUPERFAMILY SSF53822 103 256 3.24E-7 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CWR56_RS13670 d551b71f61f6df0b3974a5b7eb80f26a 395 Pfam PF12683 Protein of unknown function (DUF3798) 37 324 4.5E-104 T 29-03-2018 IPR024258 Protein of unknown function DUF3798 CWR56_RS16605 23126b729b5e9f71f4c7c00a599fa297 170 Pfam PF02417 Chromate transporter 2 165 7.5E-43 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CWR56_RS03715 539bdd71925a1a922cbb1e058b308d5a 122 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 5 121 1.5E-59 T 29-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWR56_RS14110 b22831ad29a5670356c3053874de8a68 351 Pfam PF04122 Putative cell wall binding repeat 2 59 117 9.8E-7 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS14110 b22831ad29a5670356c3053874de8a68 351 Pfam PF04122 Putative cell wall binding repeat 2 131 212 2.0E-9 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS11145 ba8bc102e8d277f565f1e2ed3dabc3f6 107 Pfam PF06125 Bacterial protein of unknown function (DUF961) 4 101 3.7E-35 T 29-03-2018 IPR010365 Protein of unknown function DUF961 CWR56_RS02825 38927690a51e2de08af559948241db8b 137 Pfam PF12675 Protein of unknown function (DUF3795) 12 76 1.4E-5 T 29-03-2018 IPR024227 Protein of unknown function DUF3795 CWR56_RS04765 3b564d4ddc19218737726a192b9bd9e0 276 Pfam PF12705 PD-(D/E)XK nuclease superfamily 116 260 2.4E-12 T 29-03-2018 CWR56_RS04765 3b564d4ddc19218737726a192b9bd9e0 276 Pfam PF12705 PD-(D/E)XK nuclease superfamily 10 97 1.1E-6 T 29-03-2018 CWR56_RS14025 f72ac4334b1f780f786477bd62d421be 318 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 72 232 2.9E-38 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR56_RS14025 f72ac4334b1f780f786477bd62d421be 318 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 72 231 2.2E-28 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR56_RS11930 31e6c79941a4f0190984ef9ca4698f50 167 Pfam PF07275 Antirestriction protein (ArdA) 7 163 2.6E-40 T 29-03-2018 IPR009899 Antirestriction CWR56_RS14970 4c60ced4dee056b3d5bb9403db0e4fa6 386 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 2 381 1.3E-153 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CWR56_RS12055 58f3df1dbe0b29f3dbc4009588c21438 382 Pfam PF05569 BlaR1 peptidase M56 12 282 1.0E-49 T 29-03-2018 IPR008756 Peptidase M56 CWR56_RS12780 9b86ad59d42b01ee234d84ee1163524a 227 SUPERFAMILY SSF81301 6 82 1.39E-6 T 29-03-2018 CWR56_RS11980 c87d98161abc81113f4509a1f8189b17 127 Pfam PF06125 Bacterial protein of unknown function (DUF961) 6 104 1.1E-33 T 29-03-2018 IPR010365 Protein of unknown function DUF961 CWR56_RS15830 b14ce4aac44cbca1859c0b7f4ff7aa1f 159 Pfam PF13151 Protein of unknown function (DUF3990) 1 153 2.6E-49 T 29-03-2018 IPR025051 Protein of unknown function DUF3990 CWR56_RS03775 530c2d849f382dd6b6af02a701536c8c 280 Pfam PF11299 Protein of unknown function (DUF3100) 19 259 1.5E-83 T 29-03-2018 IPR021450 Protein of unknown function DUF3100 CWR56_RS05050 25ee43c934f46b49108693ef05eb731c 229 Gene3D G3DSA:2.60.40.150 111 227 7.2E-4 T 29-03-2018 IPR000008 C2 domain CWR56_RS08475 952bd9541be7e05494f15f1a7557d8d6 88 Pfam PF06961 Protein of unknown function (DUF1294) 13 67 4.9E-24 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 CWR56_RS16720 ff017a00708c90467a6e408977d64a4e 569 Gene3D G3DSA:2.60.40.1730 282 451 2.6E-5 T 29-03-2018 CWR56_RS02780 5ac7bbcdb64037ef4678cc51412eeae2 73 Pfam PF11007 Spore coat associated protein JA (CotJA) 15 46 3.5E-12 T 29-03-2018 IPR020256 Spore coat protein CotJA CWR56_RS07050 45402f26ea5a931397b5c0de3d262f07 391 Pfam PF06207 Protein of unknown function (DUF1002) 34 253 4.0E-79 T 29-03-2018 IPR009343 Protein of unknown function DUF1002 CWR56_RS11160 51d03c6b08ff3183fc221bd681b9a3c1 364 Pfam PF01594 AI-2E family transporter 25 349 5.1E-63 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CWR56_RS01420 c20581f73fca2253308e7712c5516f83 138 Pfam PF12663 Protein of unknown function (DUF3788) 11 137 2.7E-41 T 29-03-2018 IPR024265 Protein of unknown function DUF3788 CWR56_RS12725 6483ed81097d773532c1acd4f222ed22 456 Pfam PF04122 Putative cell wall binding repeat 2 127 209 4.1E-14 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS12725 6483ed81097d773532c1acd4f222ed22 456 Pfam PF04122 Putative cell wall binding repeat 2 217 286 2.3E-10 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS12725 6483ed81097d773532c1acd4f222ed22 456 Pfam PF04122 Putative cell wall binding repeat 2 32 114 6.8E-15 T 29-03-2018 IPR007253 Putative cell wall binding repeat 2 CWR56_RS06660 73974036d5b5e9fff4d4638e9eca757b 34 Pfam PF13333 Integrase core domain 1 27 3.1E-6 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CWR56_RS15300 a377b7fcc9b17575130e1ee9d9886c41 269 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 13 268 1.9E-83 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWR56_RS18080 44fdd93914a815731b5efc06ea41df1e 122 Pfam PF12788 YmaF family 20 117 3.5E-38 T 29-03-2018 IPR024307 YmaF CWR56_RS08610 3b5b79ad2c2d853bce5e9724d40ff62b 126 Pfam PF14276 Domain of unknown function (DUF4363) 7 125 1.8E-24 T 29-03-2018 IPR025373 Protein of unknown function DUF4363 CWR56_RS08010 1ad89e31da1008b52cb2d1e8e38d35a5 310 Pfam PF06166 Protein of unknown function (DUF979) 10 310 5.5E-117 T 29-03-2018 IPR009323 Protein of unknown function DUF979 CWR56_RS13265 05fc7c4bd0032138c7e99ab3bfff246c 346 Pfam PF13303 Phosphotransferase system, EIIC 29 335 1.7E-55 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR56_RS04110 78a0e535e1c09ff0cef62b42026f441b 228 Pfam PF02517 CAAX protease self-immunity 117 223 1.7E-7 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR56_RS11195 d342552724b2041ba7abe47051346bf1 344 Gene3D G3DSA:1.25.40.10 127 322 1.3E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR56_RS15710 73b25697f6a67362ededcbe86bb3080f 851 Pfam PF02687 FtsX-like permease family 293 390 6.1E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS15710 73b25697f6a67362ededcbe86bb3080f 851 Pfam PF02687 FtsX-like permease family 744 836 2.3E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR56_RS13635 3e70c0fcb0365771dd27f6de477e58ed 129 Pfam PF06803 Protein of unknown function (DUF1232) 58 92 2.9E-8 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CWR56_RS18360 4261de30ceafabe3e02042bd1e72bfb7 87 Pfam PF11823 Protein of unknown function (DUF3343) 5 71 1.0E-23 T 29-03-2018 IPR021778 Domain of unknown function DUF3343 CWR56_RS00520 12bea95d86d3aa985064b54cc23e702e 393 Pfam PF07949 YbbR-like protein 222 296 2.2E-9 T 29-03-2018 IPR012505 YbbR-like CWR56_RS00520 12bea95d86d3aa985064b54cc23e702e 393 Pfam PF07949 YbbR-like protein 143 212 1.5E-5 T 29-03-2018 IPR012505 YbbR-like