locus-tag	class	description
CBEI_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBEI_RS00010	COG0592	DNA-directed DNA polymerase activity
CBEI_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CBEI_RS00030	COG0187	DNA topoisomerase II activity
CBEI_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CBEI_RS00070	COG1827	regulation of RNA biosynthetic process
CBEI_RS00110	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CBEI_RS00115	COG1074	ATP-dependent DNA helicase activity
CBEI_RS00120	COG1376	ErfK ybiS ycfS ynhG family protein
CBEI_RS00130	COG5002	protein histidine kinase activity
CBEI_RS00140	COG0688	phosphatidylethanolamine metabolic process
CBEI_RS00155	COG0488	(ABC) transporter
CBEI_RS00175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBEI_RS00180	COG1803	Methylglyoxal synthase
CBEI_RS00195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBEI_RS00215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBEI_RS00240	COG3949	Membrane
CBEI_RS00245	COG1242	4 iron, 4 sulfur cluster binding
CBEI_RS00250	COG2045	Belongs to the ComB family
CBEI_RS00260	COG0745	RESPONSE REGULATOR receiver
CBEI_RS00265	COG5002	protein histidine kinase activity
CBEI_RS00290	COG1846	Transcriptional regulator
CBEI_RS00305	COG2715	membrane protein required for spore maturation
CBEI_RS00310	COG0700	Nucleoside recognition
CBEI_RS00315	COG0006	proline dipeptidase activity
CBEI_RS00320	COG0006	proline dipeptidase activity
CBEI_RS00330	COG0084	hydrolase, TatD family'
CBEI_RS00335	COG3583	domain protein
CBEI_RS00335	COG3584	3D domain protein
CBEI_RS00340	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CBEI_RS00375	COG1141	Ferredoxin
CBEI_RS00380	COG3859	Proton-coupled thiamine transporter YuaJ
CBEI_RS00385	COG1307	EDD domain protein, DegV family
CBEI_RS00390	COG1328	CTP reductase activity
CBEI_RS00395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBEI_RS00400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBEI_RS00405	COG0602	queuosine metabolic process
CBEI_RS00410	COG2094	Belongs to the DNA glycosylase MPG family
CBEI_RS00420	COG0463	Glycosyl transferase, family 2
CBEI_RS00430	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBEI_RS00435	COG0017	Asparaginyl-tRNA synthetase
CBEI_RS00445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBEI_RS00450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBEI_RS00455	COG2088	sporulation resulting in formation of a cellular spore
CBEI_RS00460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBEI_RS00470	COG0745	RESPONSE REGULATOR receiver
CBEI_RS00475	COG3850	Histidine kinase
CBEI_RS00475	COG5002	protein histidine kinase activity
CBEI_RS00480	COG0193	aminoacyl-tRNA hydrolase activity
CBEI_RS00485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBEI_RS00495	COG2002	toxin-antitoxin pair type II binding
CBEI_RS00500	COG2244	polysaccharide biosynthetic process
CBEI_RS00505	COG3956	TIGRFAM MazG family protein
CBEI_RS00515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CBEI_RS00535	COG1098	S1 RNA binding domain
CBEI_RS00595	COG0037	tRNA processing
CBEI_RS00600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CBEI_RS00605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBEI_RS00610	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CBEI_RS00615	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CBEI_RS00620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBEI_RS00625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBEI_RS00630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBEI_RS00655	COG0423	glycine-tRNA ligase activity
CBEI_RS00660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBEI_RS00725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBEI_RS00730	COG3870	Protein conserved in bacteria
CBEI_RS00740	COG1774	PSP1 C-terminal conserved region
CBEI_RS00755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CBEI_RS00765	COG3880	PFAM UvrB UvrC protein
CBEI_RS00775	COG0542	response to heat
CBEI_RS00790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CBEI_RS00795	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CBEI_RS00800	COG4956	integral membrane protein (PIN domain superfamily)
CBEI_RS00805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBEI_RS00810	COG0442	prolyl-tRNA aminoacylation
CBEI_RS00815	COG0215	cysteine-tRNA ligase activity
CBEI_RS00825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBEI_RS00845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBEI_RS00850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBEI_RS00865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBEI_RS00870	COG0081	regulation of translation
CBEI_RS00880	COG0222	ribosome binding
CBEI_RS00885	COG0085	RNA polymerase activity
CBEI_RS00890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBEI_RS00895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBEI_RS00900	COG0049	tRNA binding
CBEI_RS00905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBEI_RS00910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBEI_RS00915	COG0051	transcription antitermination factor activity, RNA binding
CBEI_RS00920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBEI_RS00925	COG0088	Forms part of the polypeptide exit tunnel
CBEI_RS00930	COG0089	rRNA binding
CBEI_RS00935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBEI_RS00940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBEI_RS00945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBEI_RS00950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBEI_RS00955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBEI_RS00960	COG0255	Belongs to the universal ribosomal protein uL29 family
CBEI_RS00965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBEI_RS00970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBEI_RS00975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBEI_RS00980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBEI_RS00985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBEI_RS00990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBEI_RS00995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBEI_RS01000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBEI_RS01010	COG1841	ribosomal large subunit assembly
CBEI_RS01015	COG0200	Binds to the 23S rRNA
CBEI_RS01020	COG0201	protein transport
CBEI_RS01025	COG0563	adenylate kinase activity
CBEI_RS01040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBEI_RS01045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBEI_RS01050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBEI_RS01055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBEI_RS01060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBEI_RS01065	COG0202	RNA polymerase activity
CBEI_RS01070	COG0203	ribosomal protein L17
CBEI_RS01075	COG1122	ATPase activity
CBEI_RS01080	COG1122	ATPase activity
CBEI_RS01085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CBEI_RS01090	COG0101	tRNA pseudouridine synthase activity
CBEI_RS01095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBEI_RS01100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBEI_RS01105	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBEI_RS01135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBEI_RS01140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBEI_RS01145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBEI_RS01155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CBEI_RS01160	COG3773	Cell wall hydrolase
CBEI_RS01165	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CBEI_RS01175	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CBEI_RS01180	COG0280	phosphate acetyltransferase
CBEI_RS01185	COG3426	butyrate kinase activity
CBEI_RS01190	COG1418	mRNA catabolic process
CBEI_RS01195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CBEI_RS01200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CBEI_RS01200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CBEI_RS01210	COG4496	protein, YerC YecD
CBEI_RS01215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBEI_RS01225	COG0440	acetolactate synthase activity
CBEI_RS01230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBEI_RS01235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBEI_RS01240	COG0066	3-isopropylmalate dehydratase activity
CBEI_RS01245	COG0473	3-isopropylmalate dehydrogenase activity
CBEI_RS01250	COG0028	Belongs to the TPP enzyme family
CBEI_RS01255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBEI_RS01260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS01260	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS01270	COG3414	Phosphotransferase system galactitol-specific IIB component
CBEI_RS01275	COG3775	system Galactitol-specific IIC component
CBEI_RS01285	COG3959	Transketolase, thiamine diphosphate binding domain
CBEI_RS01290	COG3958	Transketolase
CBEI_RS01295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBEI_RS01300	COG0698	ribose 5-phosphate isomerase
CBEI_RS01315	COG2182	Extracellular solute-binding protein
CBEI_RS01335	COG1609	Transcriptional regulator
CBEI_RS01350	COG1136	(ABC) transporter
CBEI_RS01355	COG0577	efflux transmembrane transporter activity
CBEI_RS01360	COG0626	cystathionine gamma-synthase activity
CBEI_RS01365	COG0626	cystathionine gamma-synthase activity
CBEI_RS01375	COG2213	PTS system mannitol-specific
CBEI_RS01380	COG3711	transcriptional antiterminator
CBEI_RS01385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS01400	COG1045	serine acetyltransferase
CBEI_RS01435	COG0318	PFAM AMP-dependent synthetase and ligase
CBEI_RS01460	COG2814	Major facilitator Superfamily
CBEI_RS01465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBEI_RS01470	COG0577	efflux transmembrane transporter activity
CBEI_RS01470	COG1136	(ABC) transporter
CBEI_RS01515	COG2807	transmembrane transport
CBEI_RS01545	COG0840	transmembrane signaling receptor activity
CBEI_RS01565	COG1131	(ABC) transporter
CBEI_RS01575	COG0058	SHG alpha-glucan phosphorylase activity
CBEI_RS01585	COG0840	transmembrane signaling receptor activity
CBEI_RS01605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBEI_RS01625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBEI_RS01645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBEI_RS01650	COG1191	sigma factor activity
CBEI_RS01655	COG0726	polysaccharide deacetylase
CBEI_RS01665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBEI_RS01680	COG2076	Multidrug Resistance protein
CBEI_RS01690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBEI_RS01695	COG0840	transmembrane signaling receptor activity
CBEI_RS01705	COG2186	Transcriptional regulator
CBEI_RS01710	COG2086	electron transfer activity
CBEI_RS01715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CBEI_RS01720	COG0277	FAD linked oxidase domain protein
CBEI_RS01735	COG1882	Formate acetyltransferase
CBEI_RS01740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CBEI_RS01760	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CBEI_RS01765	COG1024	Enoyl-CoA hydratase
CBEI_RS01770	COG1960	acyl-CoA dehydrogenase activity
CBEI_RS01775	COG2086	electron transfer activity
CBEI_RS01785	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBEI_RS01800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBEI_RS01805	COG0459	protein refolding
CBEI_RS01815	COG0516	GMP reductase activity
CBEI_RS01815	COG0517	IMP dehydrogenase activity
CBEI_RS01820	COG0519	Catalyzes the synthesis of GMP from XMP
CBEI_RS01830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS01830	COG3711	transcriptional antiterminator
CBEI_RS01840	COG3730	PTS system glucitol sorbitol-specific
CBEI_RS01845	COG3732	PTS system glucitol sorbitol-specific
CBEI_RS01865	COG0166	Belongs to the GPI family
CBEI_RS01870	COG1671	Belongs to the UPF0178 family
CBEI_RS01880	COG0741	lytic transglycosylase activity
CBEI_RS01885	COG1187	pseudouridine synthase activity
CBEI_RS01890	COG0778	Nitroreductase
CBEI_RS01895	COG1733	regulation of RNA biosynthetic process
CBEI_RS01905	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CBEI_RS01920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBEI_RS01950	COG0622	Phosphoesterase
CBEI_RS02055	COG2890	protein-(glutamine-N5) methyltransferase activity
CBEI_RS02065	COG5002	protein histidine kinase activity
CBEI_RS02095	COG3590	peptidase
CBEI_RS02125	COG0312	modulator of DNA gyrase
CBEI_RS02130	COG0312	modulator of DNA gyrase
CBEI_RS02140	COG1368	sulfuric ester hydrolase activity
CBEI_RS02150	COG0492	ferredoxin-NADP+ reductase activity
CBEI_RS02165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBEI_RS02175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBEI_RS02180	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS02230	COG4466	Protein conserved in bacteria
CBEI_RS02250	COG0189	ligase activity
CBEI_RS02250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBEI_RS02255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBEI_RS02275	COG0504	CTP synthase activity
CBEI_RS02280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBEI_RS02285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBEI_RS02290	COG0254	rRNA binding
CBEI_RS02295	COG1435	thymidine kinase activity
CBEI_RS02300	COG2890	protein-(glutamine-N5) methyltransferase activity
CBEI_RS02305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBEI_RS02315	COG0009	L-threonylcarbamoyladenylate synthase
CBEI_RS02320	COG0698	ribose 5-phosphate isomerase
CBEI_RS02325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBEI_RS02335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CBEI_RS02340	COG0183	Belongs to the thiolase family
CBEI_RS02350	COG0356	it plays a direct role in the translocation of protons across the membrane
CBEI_RS02355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBEI_RS02360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBEI_RS02365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBEI_RS02370	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBEI_RS02375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBEI_RS02380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBEI_RS02385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBEI_RS02400	COG2385	sporulation resulting in formation of a cellular spore
CBEI_RS02410	COG1609	Transcriptional regulator
CBEI_RS02415	COG1077	Cell shape determining protein MreB Mrl
CBEI_RS02470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CBEI_RS02480	COG1040	competence protein
CBEI_RS02485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CBEI_RS02490	COG0653	protein targeting
CBEI_RS02495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CBEI_RS02510	COG2205	protein histidine kinase activity
CBEI_RS02520	COG2183	response to ionizing radiation
CBEI_RS02540	COG1940	carbohydrate kinase activity
CBEI_RS02550	COG1070	Carbohydrate kinase
CBEI_RS02555	COG4806	L-rhamnose isomerase
CBEI_RS02560	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CBEI_RS02565	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS02570	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CBEI_RS02580	COG2211	Major facilitator Superfamily
CBEI_RS02585	COG3254	rhamnose metabolic process
CBEI_RS02590	COG1349	DNA-binding transcription factor activity
CBEI_RS02595	COG0235	Class ii aldolase
CBEI_RS02600	COG1454	alcohol dehydrogenase
CBEI_RS02605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBEI_RS02615	COG0561	phosphatase activity
CBEI_RS02620	COG1414	Transcriptional regulator
CBEI_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS02640	COG2703	oxygen carrier activity
CBEI_RS02645	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CBEI_RS02650	COG1773	rubredoxin
CBEI_RS02660	COG0456	acetyltransferase
CBEI_RS02665	COG1214	PFAM Peptidase M22, glycoprotease
CBEI_RS02670	COG0802	atpase or kinase
CBEI_RS02685	COG0251	oxidation-reduction process
CBEI_RS02690	COG2070	2-Nitropropane dioxygenase
CBEI_RS02710	COG0420	3'-5' exonuclease activity
CBEI_RS02720	COG0803	Belongs to the bacterial solute-binding protein 9 family
CBEI_RS02745	COG1842	Phage shock protein A
CBEI_RS02755	COG0539	negative regulation of cytoplasmic translation
CBEI_RS02755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBEI_RS02765	COG2195	Cleaves the N-terminal amino acid of tripeptides
CBEI_RS02770	COG0791	NLP P60 protein
CBEI_RS02780	COG0424	maF-like protein
CBEI_RS02785	COG2003	Belongs to the UPF0758 family
CBEI_RS02790	COG1077	Cell shape determining protein MreB Mrl
CBEI_RS02795	COG1792	Involved in formation and maintenance of cell shape
CBEI_RS02805	COG0768	penicillin binding
CBEI_RS02810	COG1489	DNA binding
CBEI_RS02820	COG2894	cell division
CBEI_RS02825	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBEI_RS02830	COG0772	Belongs to the SEDS family
CBEI_RS02855	COG4399	Belongs to the UPF0754 family
CBEI_RS02870	COG1530	ribonuclease E activity
CBEI_RS02875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBEI_RS02885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBEI_RS02890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBEI_RS02895	COG1534	Rna-binding protein
CBEI_RS02900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBEI_RS02905	COG1713	HD superfamily hydrolase involved in NAD metabolism
CBEI_RS02910	COG1316	TRANSCRIPTIONal
CBEI_RS02915	COG0564	pseudouridine synthase activity
CBEI_RS02920	COG0583	DNA-binding transcription factor activity
CBEI_RS02930	COG1686	Belongs to the peptidase S11 family
CBEI_RS02955	COG3711	transcriptional antiterminator
CBEI_RS02960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS02965	COG1072	(Pantothenic acid kinase))
CBEI_RS02970	COG2213	PTS system mannitol-specific
CBEI_RS02975	COG1063	alcohol dehydrogenase
CBEI_RS02980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBEI_RS02985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CBEI_RS02990	COG0246	Mannitol dehydrogenase
CBEI_RS02995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBEI_RS03000	COG0745	RESPONSE REGULATOR receiver
CBEI_RS03005	COG5002	protein histidine kinase activity
CBEI_RS03015	COG2201	protein-glutamate methylesterase activity
CBEI_RS03030	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS03030	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS03035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS03035	COG3711	transcriptional antiterminator
CBEI_RS03045	COG3775	system Galactitol-specific IIC component
CBEI_RS03050	COG1063	alcohol dehydrogenase
CBEI_RS03055	COG3959	Transketolase, thiamine diphosphate binding domain
CBEI_RS03060	COG3958	Transketolase
CBEI_RS03065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBEI_RS03070	COG0698	ribose 5-phosphate isomerase
CBEI_RS03090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CBEI_RS03095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBEI_RS03100	COG1966	Carbon starvation protein
CBEI_RS03105	COG3275	phosphorelay sensor kinase activity
CBEI_RS03110	COG3279	Response regulator of the LytR AlgR family
CBEI_RS03115	COG0789	Transcriptional regulator
CBEI_RS03120	COG0667	Aldo Keto reductase
CBEI_RS03125	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CBEI_RS03130	COG1606	tRNA processing
CBEI_RS03135	COG1691	(AIR) carboxylase
CBEI_RS03140	COG1902	pentaerythritol trinitrate reductase activity
CBEI_RS03150	COG2766	serine protein kinase
CBEI_RS03155	COG2718	Belongs to the UPF0229 family
CBEI_RS03160	COG2719	SpoVR family
CBEI_RS03165	COG1592	Rubrerythrin
CBEI_RS03180	COG1183	phosphatidylcholine synthase activity
CBEI_RS03185	COG1597	lipid kinase activity
CBEI_RS03200	COG0517	IMP dehydrogenase activity
CBEI_RS03200	COG0516	GMP reductase activity
CBEI_RS03205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CBEI_RS03210	COG1045	serine acetyltransferase
CBEI_RS03220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBEI_RS03225	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBEI_RS03235	COG1971	Probably functions as a manganese efflux pump
CBEI_RS03240	COG0205	6-phosphofructokinase activity
CBEI_RS03245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBEI_RS03255	COG1309	transcriptional regulator
CBEI_RS03260	COG0488	(ABC) transporter
CBEI_RS03280	COG2720	vancomycin resistance protein
CBEI_RS03285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CBEI_RS03295	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBEI_RS03300	COG2390	Transcriptional regulator
CBEI_RS03305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CBEI_RS03310	COG0126	phosphoglycerate kinase activity
CBEI_RS03315	COG0149	triose-phosphate isomerase activity
CBEI_RS03320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CBEI_RS03330	COG0148	phosphopyruvate hydratase activity
CBEI_RS03340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBEI_RS03355	COG2217	Heavy metal translocating P-type atpase
CBEI_RS03395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS03405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS03410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS03425	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CBEI_RS03430	COG2873	o-acetylhomoserine
CBEI_RS03440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBEI_RS03445	COG2011	ABC-type metal ion transport system permease component
CBEI_RS03450	COG1464	Belongs to the NlpA lipoprotein family
CBEI_RS03460	COG0535	radical SAM domain protein
CBEI_RS03460	COG1433	Dinitrogenase iron-molybdenum cofactor
CBEI_RS03470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CBEI_RS03480	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CBEI_RS03485	COG0557	exoribonuclease II activity
CBEI_RS03490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBEI_RS03495	COG0737	Belongs to the 5'-nucleotidase family
CBEI_RS03500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBEI_RS03505	COG2011	ABC-type metal ion transport system permease component
CBEI_RS03510	COG1464	Belongs to the NlpA lipoprotein family
CBEI_RS03535	COG0516	GMP reductase activity
CBEI_RS03535	COG0517	IMP dehydrogenase activity
CBEI_RS03540	COG0542	response to heat
CBEI_RS03545	COG4684	Psort location CytoplasmicMembrane, score
CBEI_RS03555	COG0352	thiamine-phosphate diphosphorylase activity
CBEI_RS03560	COG0037	tRNA processing
CBEI_RS03580	COG0726	polysaccharide deacetylase
CBEI_RS03585	COG3706	GGDEF domain
CBEI_RS03595	COG0756	dUTP diphosphatase activity
CBEI_RS03610	COG3850	Histidine kinase
CBEI_RS03610	COG5002	protein histidine kinase activity
CBEI_RS03625	COG0493	'glutamate synthase
CBEI_RS03630	COG2364	Membrane
CBEI_RS03640	COG0840	transmembrane signaling receptor activity
CBEI_RS03650	COG0840	transmembrane signaling receptor activity
CBEI_RS03675	COG3328	transposase activity
CBEI_RS03695	COG2814	Major facilitator Superfamily
CBEI_RS03700	COG2207	Transcriptional regulator
CBEI_RS03700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBEI_RS03705	COG0488	(ABC) transporter
CBEI_RS03710	COG4122	O-methyltransferase activity
CBEI_RS03730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBEI_RS03740	COG1063	alcohol dehydrogenase
CBEI_RS03755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBEI_RS03775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBEI_RS03785	COG2801	Transposase and inactivated derivatives
CBEI_RS03800	COG4290	ribonuclease
CBEI_RS03805	COG2732	(Barnase) inhibitor
CBEI_RS03815	COG1263	PTS System
CBEI_RS03815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS03820	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS03830	COG1349	DNA-binding transcription factor activity
CBEI_RS03845	COG1882	Formate acetyltransferase
CBEI_RS03865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBEI_RS03880	COG3715	PTS system
CBEI_RS03885	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS03895	COG0778	Nitroreductase
CBEI_RS03900	COG2814	Major facilitator Superfamily
CBEI_RS03915	COG2801	Transposase and inactivated derivatives
CBEI_RS03940	COG3547	Transposase (IS116 IS110 IS902 family)
CBEI_RS03945	COG0778	Nitroreductase
CBEI_RS03950	COG0789	Transcriptional regulator
CBEI_RS03960	COG2226	methyltransferase
CBEI_RS03965	COG1012	belongs to the aldehyde dehydrogenase family
CBEI_RS03980	COG1653	transport
CBEI_RS03990	COG0395	ABC-type sugar transport system, permease component
CBEI_RS03995	COG0366	Alpha amylase catalytic
CBEI_RS04010	COG2814	Major facilitator Superfamily
CBEI_RS04020	COG1309	transcriptional regulator
CBEI_RS04025	COG4708	membrane
CBEI_RS04055	COG3547	Transposase (IS116 IS110 IS902 family)
CBEI_RS04065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CBEI_RS04070	COG1737	Transcriptional regulator
CBEI_RS04075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBEI_RS04080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS04080	COG2190	(PTS) system
CBEI_RS04080	COG1263	PTS System
CBEI_RS04085	COG3711	transcriptional antiterminator
CBEI_RS04095	COG3853	Toxic anion resistance protein (TelA)
CBEI_RS04100	COG0784	Response regulator, receiver
CBEI_RS04100	COG0835	chemotaxis
CBEI_RS04120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBEI_RS04130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBEI_RS04135	COG0673	inositol 2-dehydrogenase activity
CBEI_RS04140	COG1737	Transcriptional regulator
CBEI_RS04145	COG4989	oxidoreductase activity
CBEI_RS04170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBEI_RS04180	COG2207	Transcriptional regulator
CBEI_RS04180	COG4753	response regulator
CBEI_RS04195	COG1175	transmembrane transport
CBEI_RS04200	COG0395	ABC-type sugar transport system, permease component
CBEI_RS04205	COG1501	Belongs to the glycosyl hydrolase 31 family
CBEI_RS04215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBEI_RS04225	COG3118	belongs to the thioredoxin family
CBEI_RS04230	COG0386	Belongs to the glutathione peroxidase family
CBEI_RS04240	COG1846	Transcriptional regulator
CBEI_RS04255	COG2116	formate transmembrane transporter activity
CBEI_RS04280	COG0531	amino acid
CBEI_RS04285	COG0833	amino acid
CBEI_RS04295	COG1131	(ABC) transporter
CBEI_RS04300	COG1725	Transcriptional regulator
CBEI_RS04305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CBEI_RS04315	COG0157	Belongs to the NadC ModD family
CBEI_RS04345	COG2309	aminopeptidase activity
CBEI_RS04350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBEI_RS04350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBEI_RS04360	COG0741	lytic transglycosylase activity
CBEI_RS04370	COG0840	transmembrane signaling receptor activity
CBEI_RS04385	COG5002	protein histidine kinase activity
CBEI_RS04390	COG2205	protein histidine kinase activity
CBEI_RS04390	COG0745	RESPONSE REGULATOR receiver
CBEI_RS04390	COG3292	Two component regulator propeller
CBEI_RS04395	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CBEI_RS04400	COG1067	ATP-dependent peptidase activity
CBEI_RS04415	COG2172	sigma factor antagonist activity
CBEI_RS04430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBEI_RS04455	COG0268	Binds directly to 16S ribosomal RNA
CBEI_RS04485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBEI_RS04490	COG1420	regulation of RNA biosynthetic process
CBEI_RS04495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBEI_RS04500	COG0443	Heat shock 70 kDa protein
CBEI_RS04505	COG0484	heat shock protein binding
CBEI_RS04510	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBEI_RS04515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBEI_RS04520	COG2264	protein methyltransferase activity
CBEI_RS04525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CBEI_RS04530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBEI_RS04535	COG0537	adenosine 5'-monophosphoramidase activity
CBEI_RS04545	COG1610	YqeY-like protein
CBEI_RS04560	COG1480	7TM receptor with intracellular HD hydrolase
CBEI_RS04565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBEI_RS04570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBEI_RS04575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBEI_RS04590	COG0517	IMP dehydrogenase activity
CBEI_RS04595	COG0574	Belongs to the PEP-utilizing enzyme family
CBEI_RS04595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBEI_RS04610	COG0358	DNA primase activity
CBEI_RS04615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBEI_RS04640	COG1404	Belongs to the peptidase S8 family
CBEI_RS04645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CBEI_RS04655	COG3842	ATPase activity
CBEI_RS04660	COG2508	Transcriptional regulator
CBEI_RS04675	COG0058	SHG alpha-glucan phosphorylase activity
CBEI_RS04680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBEI_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS04705	COG0004	ammonium transporteR
CBEI_RS04710	COG0840	transmembrane signaling receptor activity
CBEI_RS04725	COG0840	transmembrane signaling receptor activity
CBEI_RS04730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBEI_RS04735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBEI_RS04740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CBEI_RS04785	COG1396	sequence-specific DNA binding
CBEI_RS04960	COG3299	homolog of phage Mu protein gp47
CBEI_RS04970	COG3778	Protein conserved in bacteria
CBEI_RS05010	COG1116	anion transmembrane transporter activity
CBEI_RS05015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS05020	COG1380	Effector of murein hydrolase LrgA
CBEI_RS05025	COG1346	cytolysis
CBEI_RS05035	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS05050	COG3442	glutamine amidotransferase
CBEI_RS05055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CBEI_RS05065	COG0826	peptidase U32
CBEI_RS05070	COG1193	negative regulation of DNA recombination
CBEI_RS05075	COG1683	Conserved Protein
CBEI_RS05090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS05100	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS05105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS05105	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS05110	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS05110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS05125	COG3715	PTS system
CBEI_RS05130	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS05140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS05150	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS05150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS05155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS05155	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS05160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS05160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS05165	COG3715	PTS system
CBEI_RS05170	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS05200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBEI_RS05210	COG0561	phosphatase activity
CBEI_RS05215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CBEI_RS05230	COG0477	Major facilitator Superfamily
CBEI_RS05240	COG0420	3'-5' exonuclease activity
CBEI_RS05245	COG0419	ATPase involved in DNA repair
CBEI_RS05250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBEI_RS05255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBEI_RS05265	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CBEI_RS05270	COG0728	peptidoglycan biosynthetic process
CBEI_RS05280	COG0438	transferase activity, transferring glycosyl groups
CBEI_RS05300	COG0726	polysaccharide deacetylase
CBEI_RS05305	COG0012	GTP binding
CBEI_RS05315	COG1482	cell wall glycoprotein biosynthetic process
CBEI_RS05320	COG1968	undecaprenyl-diphosphatase activity
CBEI_RS05335	COG0540	Belongs to the ATCase OTCase family
CBEI_RS05360	COG0167	dihydroorotate dehydrogenase activity
CBEI_RS05365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBEI_RS05370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CBEI_RS05410	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CBEI_RS05410	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CBEI_RS05425	COG1994	Peptidase M50
CBEI_RS05430	COG0018	arginyl-trna synthetase
CBEI_RS05435	COG0628	permease
CBEI_RS05440	COG0778	Nitroreductase
CBEI_RS05470	COG2155	Conserved Protein
CBEI_RS05475	COG1522	sequence-specific DNA binding
CBEI_RS05495	COG2996	Protein conserved in bacteria
CBEI_RS05500	COG0697	spore germination
CBEI_RS05505	COG0367	asparagine synthase
CBEI_RS05545	COG1132	(ABC) transporter
CBEI_RS05555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBEI_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS05590	COG0765	amino acid transport
CBEI_RS05595	COG1126	abc transporter atp-binding protein
CBEI_RS05605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBEI_RS05610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CBEI_RS05615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBEI_RS05620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CBEI_RS05625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBEI_RS05630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBEI_RS05635	COG0138	bifunctional purine biosynthesis protein purh
CBEI_RS05640	COG0151	Belongs to the GarS family
CBEI_RS05685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBEI_RS05700	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS05705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBEI_RS05710	COG0511	ligase activity, forming carbon-carbon bonds
CBEI_RS05715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBEI_RS05720	COG0439	Biotin carboxylase
CBEI_RS05725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBEI_RS05730	COG0825	malonyl-CoA metabolic process
CBEI_RS05745	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS05765	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS05775	COG3706	GGDEF domain
CBEI_RS05780	COG1696	Membrane protein involved in D-alanine export
CBEI_RS05815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBEI_RS05820	COG1959	2 iron, 2 sulfur cluster binding
CBEI_RS05830	COG0822	iron-sulfur transferase activity
CBEI_RS05835	COG0482	sulfurtransferase activity
CBEI_RS05850	COG0628	permease
CBEI_RS05855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBEI_RS05860	COG4472	Bacterial protein of unknown function (DUF965)
CBEI_RS05865	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBEI_RS05875	COG0735	belongs to the Fur family
CBEI_RS05880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CBEI_RS05885	COG1217	gtp-binding protein TYPA
CBEI_RS05890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBEI_RS05895	COG4122	O-methyltransferase activity
CBEI_RS05900	COG0826	peptidase U32
CBEI_RS05905	COG0768	penicillin binding
CBEI_RS05925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CBEI_RS05935	COG1191	sigma factor activity
CBEI_RS05940	COG1191	sigma factor activity
CBEI_RS05945	COG1873	PFAM PRC-barrel domain
CBEI_RS05950	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBEI_RS05955	COG1496	oxidoreductase activity
CBEI_RS05960	COG0745	RESPONSE REGULATOR receiver
CBEI_RS05965	COG5002	protein histidine kinase activity
CBEI_RS05970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBEI_RS05975	COG0573	inorganic phosphate transmembrane transporter activity
CBEI_RS05980	COG0581	inorganic phosphate transmembrane transporter activity
CBEI_RS05985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBEI_RS05990	COG0704	Plays a role in the regulation of phosphate uptake
CBEI_RS05995	COG0704	Plays a role in the regulation of phosphate uptake
CBEI_RS06005	COG1160	GTP binding
CBEI_RS06010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBEI_RS06015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CBEI_RS06030	COG1561	YicC-like family, N-terminal region
CBEI_RS06035	COG2052	Domain of unknown function (DUF370)
CBEI_RS06045	COG1758	RNA polymerase activity
CBEI_RS06050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBEI_RS06055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBEI_RS06065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBEI_RS06070	COG2738	Putative neutral zinc metallopeptidase
CBEI_RS06075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBEI_RS06075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBEI_RS06080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBEI_RS06085	COG0631	protein serine/threonine phosphatase activity
CBEI_RS06095	COG1162	GTPase activity
CBEI_RS06100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBEI_RS06105	COG1564	THIamine pyrophosphokinase
CBEI_RS06110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBEI_RS06115	COG1302	Protein conserved in bacteria
CBEI_RS06120	COG1461	Dihydroxyacetone kinase
CBEI_RS06125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBEI_RS06130	COG0742	ribosomal rna small subunit methyltransferase
CBEI_RS06135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBEI_RS06150	COG1323	Belongs to the UPF0348 family
CBEI_RS06155	COG0280	phosphate acetyltransferase
CBEI_RS06160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBEI_RS06175	COG0416	fatty acid biosynthetic process
CBEI_RS06185	COG0571	ribonuclease III activity
CBEI_RS06200	COG0552	protein localization to endoplasmic reticulum
CBEI_RS06205	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CBEI_RS06210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBEI_RS06215	COG0228	four-way junction DNA binding
CBEI_RS06220	COG1837	Belongs to the UPF0109 family
CBEI_RS06225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBEI_RS06230	COG0336	Belongs to the RNA methyltransferase TrmD family
CBEI_RS06235	COG0335	large ribosomal subunit rRNA binding
CBEI_RS06245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBEI_RS06250	COG0792	nuclease activity
CBEI_RS06260	COG0758	DNA mediated transformation
CBEI_RS06265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBEI_RS06270	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CBEI_RS06275	COG0052	Belongs to the universal ribosomal protein uS2 family
CBEI_RS06290	COG0233	cytoplasmic translational termination
CBEI_RS06300	COG4589	Belongs to the CDS family
CBEI_RS06310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBEI_RS06320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CBEI_RS06325	COG0779	Required for maturation of 30S ribosomal subunits
CBEI_RS06330	COG0195	Participates in both transcription termination and antitermination
CBEI_RS06335	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CBEI_RS06345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBEI_RS06350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBEI_RS06365	COG0196	riboflavin kinase activity
CBEI_RS06370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBEI_RS06375	COG1185	polyribonucleotide nucleotidyltransferase activity
CBEI_RS06380	COG0612	Peptidase, M16
CBEI_RS06390	COG0527	aspartate kinase activity
CBEI_RS06395	COG0740	serine-type endopeptidase activity
CBEI_RS06405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBEI_RS06410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CBEI_RS06415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBEI_RS06420	COG1418	mRNA catabolic process
CBEI_RS06425	COG2359	stage V sporulation protein S
CBEI_RS06440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CBEI_RS06465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBEI_RS06465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CBEI_RS06470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBEI_RS06475	COG1609	Transcriptional regulator
CBEI_RS06495	COG1874	Beta-galactosidase
CBEI_RS06500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBEI_RS06505	COG2972	Histidine kinase
CBEI_RS06510	COG2207	Transcriptional regulator
CBEI_RS06510	COG4753	response regulator
CBEI_RS06520	COG1854	S-ribosylhomocysteine lyase activity
CBEI_RS06540	COG3875	lactate racemase activity
CBEI_RS06555	COG3158	transport of potassium into the cell
CBEI_RS06560	COG2078	PFAM AMMECR1 domain protein
CBEI_RS06560	COG3885	ferrous iron binding
CBEI_RS06595	COG1309	transcriptional regulator
CBEI_RS06600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBEI_RS06605	COG0697	spore germination
CBEI_RS06610	COG1396	sequence-specific DNA binding
CBEI_RS06620	COG2099	Precorrin-6x reductase
CBEI_RS06635	COG1705	Flagellar rod assembly protein muramidase FlgJ
CBEI_RS06640	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CBEI_RS06645	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CBEI_RS06655	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CBEI_RS06665	COG0406	alpha-ribazole phosphatase activity
CBEI_RS06675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBEI_RS06690	COG1492	cobalamin metabolic process
CBEI_RS06705	COG0561	phosphatase activity
CBEI_RS06720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CBEI_RS06725	COG2706	6-phosphogluconolactonase activity
CBEI_RS06730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CBEI_RS06735	COG3647	Membrane
CBEI_RS06745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBEI_RS06750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CBEI_RS06760	COG0181	hydroxymethylbilane synthase activity
CBEI_RS06770	COG0113	porphobilinogen synthase activity
CBEI_RS06775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBEI_RS06800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CBEI_RS06805	COG0083	homoserine kinase activity
CBEI_RS06810	COG4492	Belongs to the UPF0735 family
CBEI_RS06865	COG3708	Transcriptional regulator
CBEI_RS06865	COG2207	Transcriptional regulator
CBEI_RS06870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBEI_RS06885	COG2084	Dehydrogenase
CBEI_RS06905	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBEI_RS06910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBEI_RS06915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBEI_RS06920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBEI_RS06925	COG0131	Imidazoleglycerol-phosphate dehydratase
CBEI_RS06930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CBEI_RS06935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBEI_RS06940	COG0107	imidazoleglycerol-phosphate synthase activity
CBEI_RS06945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBEI_RS06950	COG0140	phosphoribosyl-ATP diphosphatase activity
CBEI_RS06965	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBEI_RS06975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBEI_RS06980	COG1067	ATP-dependent peptidase activity
CBEI_RS06980	COG0470	DNA polymerase III
CBEI_RS06985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBEI_RS06990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBEI_RS07015	COG0735	belongs to the Fur family
CBEI_RS07030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CBEI_RS07060	COG3422	double-strand break repair
CBEI_RS07260	COG2207	Transcriptional regulator
CBEI_RS07260	COG4753	response regulator
CBEI_RS07265	COG2972	Histidine kinase
CBEI_RS07270	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBEI_RS07280	COG0849	cell division
CBEI_RS07285	COG1473	amidohydrolase
CBEI_RS07290	COG0564	pseudouridine synthase activity
CBEI_RS07295	COG2244	polysaccharide biosynthetic process
CBEI_RS07300	COG2244	polysaccharide biosynthetic process
CBEI_RS07305	COG0840	transmembrane signaling receptor activity
CBEI_RS07310	COG0840	transmembrane signaling receptor activity
CBEI_RS07345	COG2801	Transposase and inactivated derivatives
CBEI_RS07355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBEI_RS07365	COG1410	methionine synthase
CBEI_RS07365	COG0646	methionine synthase
CBEI_RS07400	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CBEI_RS07405	COG1362	aminopeptidase activity
CBEI_RS07410	COG0613	PHP domain protein
CBEI_RS07430	COG0484	heat shock protein binding
CBEI_RS07440	COG1773	rubredoxin
CBEI_RS07440	COG1592	Rubrerythrin
CBEI_RS07445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CBEI_RS07460	COG4632	Exopolysaccharide biosynthesis protein
CBEI_RS07460	COG5434	Belongs to the glycosyl hydrolase 28 family
CBEI_RS07475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBEI_RS07495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBEI_RS07500	COG0840	transmembrane signaling receptor activity
CBEI_RS07505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBEI_RS07510	COG2364	Membrane
CBEI_RS07515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBEI_RS07530	COG1151	hydroxylamine reductase activity
CBEI_RS07535	COG2608	mercury ion transmembrane transporter activity
CBEI_RS07580	COG0366	Alpha amylase catalytic
CBEI_RS07585	COG4086	secreted protein
CBEI_RS07590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CBEI_RS07605	COG2217	Heavy metal translocating P-type atpase
CBEI_RS07615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CBEI_RS07630	COG1404	Belongs to the peptidase S8 family
CBEI_RS07640	COG1404	Belongs to the peptidase S8 family
CBEI_RS07655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CBEI_RS07675	COG1063	alcohol dehydrogenase
CBEI_RS07685	COG0493	'glutamate synthase
CBEI_RS07695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CBEI_RS07705	COG3384	dioxygenase
CBEI_RS07710	COG1733	regulation of RNA biosynthetic process
CBEI_RS07740	COG1114	Component of the transport system for branched-chain amino acids
CBEI_RS07745	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS07755	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS07760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS07770	COG3279	Response regulator of the LytR AlgR family
CBEI_RS07780	COG4864	UPF0365 protein
CBEI_RS07790	COG4191	Histidine kinase
CBEI_RS07820	COG0582	viral genome integration into host DNA
CBEI_RS07870	COG1695	Transcriptional regulator
CBEI_RS07920	COG0129	dihydroxy-acid dehydratase activity
CBEI_RS07935	COG1802	Transcriptional regulator
CBEI_RS07945	COG1331	Highly conserved protein containing a thioredoxin domain
CBEI_RS07950	COG1131	(ABC) transporter
CBEI_RS07965	COG2022	thiamine diphosphate biosynthetic process
CBEI_RS07980	COG2814	Major facilitator Superfamily
CBEI_RS07985	COG0516	GMP reductase activity
CBEI_RS07985	COG0517	IMP dehydrogenase activity
CBEI_RS08005	COG1376	ErfK ybiS ycfS ynhG family protein
CBEI_RS08025	COG0632	four-way junction helicase activity
CBEI_RS08030	COG2255	four-way junction helicase activity
CBEI_RS08035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBEI_RS08055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBEI_RS08060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBEI_RS08065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CBEI_RS08065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBEI_RS08070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBEI_RS08075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBEI_RS08080	COG1490	D-aminoacyl-tRNA deacylase activity
CBEI_RS08085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBEI_RS08090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBEI_RS08100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBEI_RS08110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBEI_RS08115	COG1811	Na channel or pump
CBEI_RS08125	COG0460	homoserine dehydrogenase
CBEI_RS08135	COG5002	protein histidine kinase activity
CBEI_RS08160	COG0572	uridine kinase
CBEI_RS08165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBEI_RS08175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBEI_RS08185	COG0488	(ABC) transporter
CBEI_RS08215	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBEI_RS08220	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBEI_RS08225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBEI_RS08230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBEI_RS08240	COG2001	Belongs to the MraZ family
CBEI_RS08245	COG0275	rRNA processing
CBEI_RS08255	COG0768	penicillin binding
CBEI_RS08260	COG0768	penicillin binding
CBEI_RS08270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CBEI_RS08275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBEI_RS08280	COG0772	Belongs to the SEDS family
CBEI_RS08305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CBEI_RS08310	COG1799	cell septum assembly
CBEI_RS08325	COG3599	regulation of cell shape
CBEI_RS08330	COG1360	Flagellar Motor Protein
CBEI_RS08335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CBEI_RS08340	COG0564	pseudouridine synthase activity
CBEI_RS08345	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CBEI_RS08350	COG0116	Belongs to the methyltransferase superfamily
CBEI_RS08385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBEI_RS08390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CBEI_RS08435	COG0326	Molecular chaperone. Has ATPase activity
CBEI_RS08480	COG3935	DnaD domain protein
CBEI_RS08540	COG5484	DNA packaging
CBEI_RS08700	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS08755	COG1285	pathogenesis
CBEI_RS08765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBEI_RS08770	COG1459	type II secretion system
CBEI_RS08820	COG3854	ATPases associated with a variety of cellular activities
CBEI_RS08860	COG1302	Protein conserved in bacteria
CBEI_RS08865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBEI_RS08870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBEI_RS08875	COG1570	exodeoxyribonuclease VII activity
CBEI_RS08880	COG1722	exodeoxyribonuclease VII activity
CBEI_RS08885	COG0142	geranyltranstransferase activity
CBEI_RS08890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBEI_RS08895	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CBEI_RS08900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CBEI_RS08905	COG1438	arginine binding
CBEI_RS08910	COG0497	DNA recombination
CBEI_RS08915	COG0750	zinc metalloprotease
CBEI_RS08920	COG0745	RESPONSE REGULATOR receiver
CBEI_RS08925	COG2703	oxygen carrier activity
CBEI_RS08935	COG2233	PERMEase
CBEI_RS08955	COG0406	alpha-ribazole phosphatase activity
CBEI_RS08970	COG0840	transmembrane signaling receptor activity
CBEI_RS08975	COG0463	Glycosyl transferase, family 2
CBEI_RS08980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBEI_RS08990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBEI_RS09000	COG1819	glycosyl
CBEI_RS09005	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CBEI_RS09010	COG0745	RESPONSE REGULATOR receiver
CBEI_RS09015	COG5002	protein histidine kinase activity
CBEI_RS09035	COG1595	DNA-templated transcription, initiation
CBEI_RS09040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBEI_RS09045	COG3022	response to hydroperoxide
CBEI_RS09050	COG1234	tRNA 3'-trailer cleavage
CBEI_RS09090	COG1959	2 iron, 2 sulfur cluster binding
CBEI_RS09105	COG0512	Glutamine amidotransferase of anthranilate synthase
CBEI_RS09105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBEI_RS09110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBEI_RS09115	COG0134	indole-3-glycerol-phosphate synthase activity
CBEI_RS09120	COG0135	phosphoribosylanthranilate isomerase activity
CBEI_RS09125	COG0133	tryptophan synthase activity
CBEI_RS09130	COG0159	tryptophan synthase activity
CBEI_RS09165	COG0588	phosphoglycerate mutase activity
CBEI_RS09170	COG0534	Mate efflux family protein
CBEI_RS09185	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS09195	COG0411	ABC transporter
CBEI_RS09215	COG3706	GGDEF domain
CBEI_RS09230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBEI_RS09245	COG0306	phosphate transporter
CBEI_RS09255	COG1408	metallophosphoesterase
CBEI_RS09265	COG0346	lactoylglutathione lyase activity
CBEI_RS09270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CBEI_RS09280	COG0861	Integral membrane protein TerC family
CBEI_RS09320	COG2171	N-acyltransferase activity
CBEI_RS09325	COG0436	Aminotransferase
CBEI_RS09330	COG3123	guanosine phosphorylase activity
CBEI_RS09345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBEI_RS09350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBEI_RS09360	COG2226	methyltransferase
CBEI_RS09365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CBEI_RS09375	COG1187	pseudouridine synthase activity
CBEI_RS09385	COG5002	protein histidine kinase activity
CBEI_RS09390	COG0745	RESPONSE REGULATOR receiver
CBEI_RS09405	COG1136	(ABC) transporter
CBEI_RS09410	COG0577	efflux transmembrane transporter activity
CBEI_RS09410	COG1136	(ABC) transporter
CBEI_RS09425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBEI_RS09430	COG1363	Peptidase, m42
CBEI_RS09435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBEI_RS09455	COG0701	Predicted permease
CBEI_RS09460	COG3689	TIGRFAM TIGR03943 family protein
CBEI_RS09480	COG0024	Methionine aminopeptidase
CBEI_RS09485	COG0514	ATP-dependent DNA helicase (RecQ)
CBEI_RS09490	COG0484	heat shock protein binding
CBEI_RS09495	COG1191	sigma factor activity
CBEI_RS09505	COG0646	methionine synthase
CBEI_RS09505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CBEI_RS09515	COG0493	'glutamate synthase
CBEI_RS09520	COG1609	Transcriptional regulator
CBEI_RS09525	COG1904	glucuronate isomerase
CBEI_RS09530	COG0246	Mannitol dehydrogenase
CBEI_RS09540	COG2211	Major facilitator Superfamily
CBEI_RS09545	COG0800	Aldolase
CBEI_RS09550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS09555	COG0246	Mannitol dehydrogenase
CBEI_RS09560	COG2721	sulfolactate sulfo-lyase activity
CBEI_RS09565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS09565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS09575	COG1349	DNA-binding transcription factor activity
CBEI_RS09580	COG1105	Belongs to the carbohydrate kinase PfkB family
CBEI_RS09585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS09585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBEI_RS09585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CBEI_RS09600	COG1959	2 iron, 2 sulfur cluster binding
CBEI_RS09605	COG0396	ATPase activity
CBEI_RS09610	COG0719	Fe-S assembly protein
CBEI_RS09615	COG0719	Fe-S assembly protein
CBEI_RS09620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBEI_RS09625	COG0822	iron-sulfur transferase activity
CBEI_RS09635	COG1404	Belongs to the peptidase S8 family
CBEI_RS09655	COG1307	EDD domain protein, DegV family
CBEI_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS09670	COG0534	Mate efflux family protein
CBEI_RS09700	COG2966	Psort location CytoplasmicMembrane, score
CBEI_RS09705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBEI_RS09730	COG1686	Belongs to the peptidase S11 family
CBEI_RS09740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBEI_RS09745	COG3874	Sporulation protein YtfJ
CBEI_RS09755	COG1686	Belongs to the peptidase S11 family
CBEI_RS09765	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CBEI_RS09785	COG1725	Transcriptional regulator
CBEI_RS09790	COG1131	(ABC) transporter
CBEI_RS09805	COG1187	pseudouridine synthase activity
CBEI_RS09815	COG0617	tRNA 3'-terminal CCA addition
CBEI_RS09825	COG0840	transmembrane signaling receptor activity
CBEI_RS09840	COG1704	LemA family
CBEI_RS09845	COG0598	Magnesium transport protein CorA
CBEI_RS09855	COG0346	lactoylglutathione lyase activity
CBEI_RS09860	COG0768	penicillin binding
CBEI_RS09880	COG1329	Transcriptional regulator
CBEI_RS09895	COG3069	C4-dicarboxylate transmembrane transporter activity
CBEI_RS09915	COG1268	BioY protein
CBEI_RS09920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBEI_RS09935	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CBEI_RS09940	COG1263	PTS System
CBEI_RS09940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS09950	COG1737	Transcriptional regulator
CBEI_RS09955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBEI_RS09965	COG2814	Major facilitator Superfamily
CBEI_RS09980	COG1695	Transcriptional regulator
CBEI_RS10010	COG1979	alcohol dehydrogenase
CBEI_RS10015	COG0445	tRNA wobble uridine modification
CBEI_RS10030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBEI_RS10035	COG1454	alcohol dehydrogenase
CBEI_RS10040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CBEI_RS10045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS10050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS10055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBEI_RS10075	COG0517	IMP dehydrogenase activity
CBEI_RS10080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBEI_RS10085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CBEI_RS10135	COG1012	belongs to the aldehyde dehydrogenase family
CBEI_RS10140	COG2814	Major facilitator Superfamily
CBEI_RS10175	COG0824	Thioesterase
CBEI_RS10185	COG0583	DNA-binding transcription factor activity
CBEI_RS10190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBEI_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS10205	COG4974	Belongs to the 'phage' integrase family
CBEI_RS10220	COG0726	polysaccharide deacetylase
CBEI_RS10225	COG3842	ATPase activity
CBEI_RS10230	COG4149	molybdate abc transporter
CBEI_RS10235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBEI_RS10240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBEI_RS10245	COG0549	Belongs to the carbamate kinase family
CBEI_RS10260	COG0402	S-adenosylhomocysteine deaminase activity
CBEI_RS10265	COG0493	'glutamate synthase
CBEI_RS10265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBEI_RS10270	COG2252	PERMEase
CBEI_RS10275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CBEI_RS10280	COG1309	transcriptional regulator
CBEI_RS10290	COG0402	S-adenosylhomocysteine deaminase activity
CBEI_RS10295	COG0251	oxidation-reduction process
CBEI_RS10300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CBEI_RS10300	COG3608	succinylglutamate desuccinylase aspartoacylase
CBEI_RS10310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CBEI_RS10315	COG1213	nucleotidyl transferase
CBEI_RS10335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBEI_RS10350	COG0315	cyclic pyranopterin monophosphate synthase activity
CBEI_RS10360	COG0725	ABC transporter, periplasmic molybdate-binding protein
CBEI_RS10365	COG3585	molybdate ion transport
CBEI_RS10380	COG1910	domain protein
CBEI_RS10405	COG0347	Belongs to the P(II) protein family
CBEI_RS10435	COG0535	radical SAM domain protein
CBEI_RS10440	COG0535	radical SAM domain protein
CBEI_RS10445	COG1522	sequence-specific DNA binding
CBEI_RS10450	COG1522	sequence-specific DNA binding
CBEI_RS10475	COG1199	ATP-dependent helicase activity
CBEI_RS10475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBEI_RS10485	COG0789	Transcriptional regulator
CBEI_RS10505	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CBEI_RS10530	COG2205	protein histidine kinase activity
CBEI_RS10535	COG0745	RESPONSE REGULATOR receiver
CBEI_RS10540	COG3158	transport of potassium into the cell
CBEI_RS10550	COG2801	Transposase and inactivated derivatives
CBEI_RS10560	COG1024	Enoyl-CoA hydratase
CBEI_RS10565	COG1960	acyl-CoA dehydrogenase activity
CBEI_RS10570	COG2086	electron transfer activity
CBEI_RS10580	COG2030	dehydratase
CBEI_RS10585	COG3829	transcription factor binding
CBEI_RS10585	COG3290	protein histidine kinase activity
CBEI_RS10590	COG4670	ketone body catabolic process
CBEI_RS10595	COG2610	gluconate transmembrane transporter activity
CBEI_RS10605	COG2207	Transcriptional regulator
CBEI_RS10605	COG3708	Transcriptional regulator
CBEI_RS10610	COG2521	methyltransferase
CBEI_RS10610	COG2136	Putative SAM-dependent methyltransferase
CBEI_RS10635	COG3850	Histidine kinase
CBEI_RS10635	COG5002	protein histidine kinase activity
CBEI_RS10640	COG1136	(ABC) transporter
CBEI_RS10670	COG0431	NADPH-dependent FMN reductase
CBEI_RS10670	COG3976	FMN-binding domain protein
CBEI_RS10670	COG1053	succinate dehydrogenase
CBEI_RS10685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CBEI_RS10690	COG0653	protein targeting
CBEI_RS10700	COG0004	ammonium transporteR
CBEI_RS10710	COG3848	Pyruvate phosphate dikinase
CBEI_RS10710	COG0574	Belongs to the PEP-utilizing enzyme family
CBEI_RS10715	COG1309	transcriptional regulator
CBEI_RS10720	COG1309	transcriptional regulator
CBEI_RS10725	COG0574	Belongs to the PEP-utilizing enzyme family
CBEI_RS10725	COG3848	Pyruvate phosphate dikinase
CBEI_RS10740	COG3546	catalase activity
CBEI_RS10755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS10760	COG3852	Histidine kinase
CBEI_RS10770	COG1051	belongs to the nudix hydrolase family
CBEI_RS10770	COG1056	cytidyltransferase-related domain
CBEI_RS10800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBEI_RS10805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBEI_RS10825	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CBEI_RS10830	COG5002	protein histidine kinase activity
CBEI_RS10830	COG3850	Histidine kinase
CBEI_RS10835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CBEI_RS10840	COG1116	anion transmembrane transporter activity
CBEI_RS10845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS10850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBEI_RS10870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBEI_RS10875	COG0318	PFAM AMP-dependent synthetase and ligase
CBEI_RS10890	COG3290	protein histidine kinase activity
CBEI_RS10890	COG3829	transcription factor binding
CBEI_RS10900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CBEI_RS10910	COG0427	acetyl-CoA hydrolase
CBEI_RS10925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CBEI_RS10955	COG0798	PFAM Bile acid sodium symporter
CBEI_RS10965	COG0516	GMP reductase activity
CBEI_RS10965	COG0517	IMP dehydrogenase activity
CBEI_RS10970	COG1193	negative regulation of DNA recombination
CBEI_RS10985	COG5002	protein histidine kinase activity
CBEI_RS11000	COG2267	carboxylic ester hydrolase activity
CBEI_RS11005	COG3104	oligopeptide transport
CBEI_RS11025	COG0017	Asparaginyl-tRNA synthetase
CBEI_RS11030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBEI_RS11035	COG0154	amidase activity
CBEI_RS11040	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBEI_RS11065	COG0450	alkyl hydroperoxide reductase
CBEI_RS11080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBEI_RS11085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBEI_RS11090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBEI_RS11095	COG1120	ATPase activity
CBEI_RS11105	COG0583	DNA-binding transcription factor activity
CBEI_RS11115	COG1132	(ABC) transporter
CBEI_RS11120	COG0726	polysaccharide deacetylase
CBEI_RS11125	COG3829	transcription factor binding
CBEI_RS11125	COG3290	protein histidine kinase activity
CBEI_RS11130	COG2376	Dihydroxyacetone kinase
CBEI_RS11140	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CBEI_RS11160	COG2814	Major facilitator Superfamily
CBEI_RS11170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBEI_RS11170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBEI_RS11215	COG2703	oxygen carrier activity
CBEI_RS11245	COG2972	Histidine kinase
CBEI_RS11245	COG0745	RESPONSE REGULATOR receiver
CBEI_RS11250	COG3279	Response regulator of the LytR AlgR family
CBEI_RS11255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBEI_RS11260	COG1393	Belongs to the ArsC family
CBEI_RS11265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBEI_RS11270	COG1742	UPF0060 membrane protein
CBEI_RS11305	COG0493	'glutamate synthase
CBEI_RS11310	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CBEI_RS11325	COG0840	transmembrane signaling receptor activity
CBEI_RS11355	COG1253	flavin adenine dinucleotide binding
CBEI_RS11360	COG1737	Transcriptional regulator
CBEI_RS11365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CBEI_RS11370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBEI_RS11375	COG0371	Dehydrogenase
CBEI_RS11385	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS11390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS11405	COG1312	Catalyzes the dehydration of D-mannonate
CBEI_RS11410	COG0800	Aldolase
CBEI_RS11430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBEI_RS11435	COG3576	pyridoxamine 5-phosphate
CBEI_RS11445	COG0456	acetyltransferase
CBEI_RS11495	COG1484	DNA-dependent DNA replication
CBEI_RS11500	COG2002	toxin-antitoxin pair type II binding
CBEI_RS11540	COG1378	Sugar-specific transcriptional regulator TrmB
CBEI_RS11550	COG1473	amidohydrolase
CBEI_RS11560	COG1024	Enoyl-CoA hydratase
CBEI_RS11565	COG1760	l-serine dehydratase
CBEI_RS11570	COG0840	transmembrane signaling receptor activity
CBEI_RS11575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CBEI_RS11595	COG0477	Major facilitator Superfamily
CBEI_RS11615	COG1733	regulation of RNA biosynthetic process
CBEI_RS11620	COG2130	NADP-dependent
CBEI_RS11625	COG1733	regulation of RNA biosynthetic process
CBEI_RS11630	COG2801	Transposase and inactivated derivatives
CBEI_RS11665	COG0745	RESPONSE REGULATOR receiver
CBEI_RS11695	COG1819	glycosyl
CBEI_RS11700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CBEI_RS11740	COG1484	DNA-dependent DNA replication
CBEI_RS11745	COG2002	toxin-antitoxin pair type II binding
CBEI_RS11755	COG3617	BRO family, N-terminal domain
CBEI_RS11785	COG1151	hydroxylamine reductase activity
CBEI_RS11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBEI_RS11800	COG1773	rubredoxin
CBEI_RS11805	COG1151	hydroxylamine reductase activity
CBEI_RS11815	COG1012	belongs to the aldehyde dehydrogenase family
CBEI_RS11825	COG1151	hydroxylamine reductase activity
CBEI_RS11840	COG1376	ErfK ybiS ycfS ynhG family protein
CBEI_RS11935	COG0582	viral genome integration into host DNA
CBEI_RS11970	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CBEI_RS11980	COG2242	protein methyltransferase activity
CBEI_RS12005	COG2188	Transcriptional regulator
CBEI_RS12010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS12010	COG1263	PTS System
CBEI_RS12015	COG0366	Alpha amylase catalytic
CBEI_RS12035	COG1592	Rubrerythrin
CBEI_RS12035	COG1773	rubredoxin
CBEI_RS12050	COG0583	DNA-binding transcription factor activity
CBEI_RS12055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBEI_RS12060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBEI_RS12075	COG2357	RelA SpoT domain protein
CBEI_RS12090	COG0432	Pfam Uncharacterised protein family UPF0047
CBEI_RS12100	COG2703	oxygen carrier activity
CBEI_RS12120	COG1027	Aspartate ammonia-lyase
CBEI_RS12125	COG1522	sequence-specific DNA binding
CBEI_RS12165	COG0726	polysaccharide deacetylase
CBEI_RS12170	COG3830	Belongs to the UPF0237 family
CBEI_RS12175	COG2848	UPF0210 protein
CBEI_RS12190	COG0708	Exodeoxyribonuclease III
CBEI_RS12200	COG1653	transport
CBEI_RS12205	COG1175	transmembrane transport
CBEI_RS12210	COG0395	ABC-type sugar transport system, permease component
CBEI_RS12215	COG3534	alpha-L-arabinofuranosidase
CBEI_RS12225	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS12225	COG4977	sequence-specific DNA binding
CBEI_RS12245	COG0494	nUDIX hydrolase
CBEI_RS12250	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBEI_RS12290	COG1522	sequence-specific DNA binding
CBEI_RS12295	COG1335	isochorismatase
CBEI_RS12305	COG2972	Histidine kinase
CBEI_RS12310	COG2207	Transcriptional regulator
CBEI_RS12310	COG4753	response regulator
CBEI_RS12315	COG4213	ABC transporter substrate-binding protein
CBEI_RS12320	COG1129	ABC transporter
CBEI_RS12325	COG4214	carbohydrate transport
CBEI_RS12335	COG1070	Carbohydrate kinase
CBEI_RS12350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBEI_RS12370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS12375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS12380	COG0765	amino acid transport
CBEI_RS12385	COG1126	abc transporter atp-binding protein
CBEI_RS12390	COG0252	asparaginase activity
CBEI_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS12415	COG0745	RESPONSE REGULATOR receiver
CBEI_RS12420	COG0612	Peptidase, M16
CBEI_RS12425	COG2137	regulation of response to DNA damage stimulus
CBEI_RS12445	COG4632	Exopolysaccharide biosynthesis protein
CBEI_RS12445	COG5434	Belongs to the glycosyl hydrolase 28 family
CBEI_RS12475	COG0494	nUDIX hydrolase
CBEI_RS12480	COG0534	Mate efflux family protein
CBEI_RS12495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBEI_RS12505	COG0248	Ppx GppA phosphatase
CBEI_RS12510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CBEI_RS12520	COG1979	alcohol dehydrogenase
CBEI_RS12550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBEI_RS12555	COG2195	Cleaves the N-terminal amino acid of tripeptides
CBEI_RS12570	COG1136	(ABC) transporter
CBEI_RS12575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBEI_RS12585	COG0791	NLP P60 protein
CBEI_RS12605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBEI_RS12645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBEI_RS12660	COG4656	Part of a membrane complex involved in electron transport
CBEI_RS12665	COG4658	electron transport chain
CBEI_RS12670	COG4659	FMN binding
CBEI_RS12675	COG4660	Part of a membrane complex involved in electron transport
CBEI_RS12680	COG4657	Part of a membrane complex involved in electron transport
CBEI_RS12685	COG2878	Part of a membrane complex involved in electron transport
CBEI_RS12685	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBEI_RS12700	COG1609	Transcriptional regulator
CBEI_RS12705	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CBEI_RS12715	COG3300	MHYT domain
CBEI_RS12715	COG5001	Diguanylate cyclase
CBEI_RS12720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBEI_RS12730	COG0523	cobalamin synthesis protein
CBEI_RS12740	COG0561	phosphatase activity
CBEI_RS12745	COG1349	DNA-binding transcription factor activity
CBEI_RS12750	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CBEI_RS12785	COG5002	protein histidine kinase activity
CBEI_RS12795	COG1309	transcriptional regulator
CBEI_RS12800	COG1566	PFAM secretion protein HlyD family protein
CBEI_RS12815	COG1309	transcriptional regulator
CBEI_RS12845	COG5002	protein histidine kinase activity
CBEI_RS12850	COG0328	RNA-DNA hybrid ribonuclease activity
CBEI_RS12855	COG0653	protein targeting
CBEI_RS12860	COG2388	GCN5-related N-acetyl-transferase
CBEI_RS12865	COG1683	Conserved Protein
CBEI_RS12870	COG1592	Rubrerythrin
CBEI_RS12870	COG1773	rubredoxin
CBEI_RS12875	COG5001	Diguanylate cyclase
CBEI_RS12875	COG3300	MHYT domain
CBEI_RS12885	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS12890	COG3875	lactate racemase activity
CBEI_RS12895	COG3142	Participates in the control of copper homeostasis
CBEI_RS12900	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS12900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS12910	COG3414	Phosphotransferase system galactitol-specific IIB component
CBEI_RS12915	COG3775	system Galactitol-specific IIC component
CBEI_RS12920	COG0371	Dehydrogenase
CBEI_RS12930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBEI_RS12940	COG5002	protein histidine kinase activity
CBEI_RS12960	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CBEI_RS12965	COG3584	3D domain protein
CBEI_RS12965	COG3583	domain protein
CBEI_RS12970	COG0765	amino acid transport
CBEI_RS12975	COG0765	amino acid transport
CBEI_RS12980	COG1126	abc transporter atp-binding protein
CBEI_RS12985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS12990	COG3437	response regulator, receiver
CBEI_RS12995	COG2205	protein histidine kinase activity
CBEI_RS12995	COG0784	Response regulator, receiver
CBEI_RS12995	COG5002	protein histidine kinase activity
CBEI_RS13000	COG2201	protein-glutamate methylesterase activity
CBEI_RS13005	COG0730	response to heat
CBEI_RS13020	COG0534	Mate efflux family protein
CBEI_RS13030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBEI_RS13040	COG0561	phosphatase activity
CBEI_RS13055	COG2200	EAL domain
CBEI_RS13055	COG3287	FIST C domain
CBEI_RS13055	COG2199	diguanylate cyclase activity
CBEI_RS13065	COG2860	membrane
CBEI_RS13070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBEI_RS13080	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBEI_RS13120	COG0602	queuosine metabolic process
CBEI_RS13125	COG0302	gtp cyclohydrolase
CBEI_RS13130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBEI_RS13135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBEI_RS13140	COG2081	HI0933 family
CBEI_RS13150	COG0539	negative regulation of cytoplasmic translation
CBEI_RS13150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBEI_RS13155	COG0494	nUDIX hydrolase
CBEI_RS13170	COG1528	Iron-storage protein
CBEI_RS13195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBEI_RS13200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBEI_RS13205	COG4974	Belongs to the 'phage' integrase family
CBEI_RS13220	COG1956	GAF domain-containing protein
CBEI_RS13225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBEI_RS13230	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CBEI_RS13235	COG1923	regulation of RNA biosynthetic process
CBEI_RS13240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBEI_RS13245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CBEI_RS13255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CBEI_RS13265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CBEI_RS13285	COG0390	transport system, permease component
CBEI_RS13290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBEI_RS13295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBEI_RS13300	COG0561	phosphatase activity
CBEI_RS13315	COG1091	dTDP-4-dehydrorhamnose reductase activity
CBEI_RS13380	COG0463	Glycosyl transferase, family 2
CBEI_RS13380	COG0457	Tetratricopeptide repeat
CBEI_RS13390	COG1216	Glycosyl transferase, family 2
CBEI_RS13390	COG0463	Glycosyl transferase, family 2
CBEI_RS13425	COG1231	oxidoreductase activity
CBEI_RS13430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBEI_RS13455	COG1215	transferase activity, transferring glycosyl groups
CBEI_RS13475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CBEI_RS13480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBEI_RS13485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CBEI_RS13495	COG1285	pathogenesis
CBEI_RS13575	COG5444	nuclease activity
CBEI_RS13650	COG1285	pathogenesis
CBEI_RS13665	COG0488	(ABC) transporter
CBEI_RS13670	COG0028	Belongs to the TPP enzyme family
CBEI_RS13675	COG0440	acetolactate synthase activity
CBEI_RS13680	COG3976	FMN-binding domain protein
CBEI_RS13680	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CBEI_RS13700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CBEI_RS13710	COG0534	Mate efflux family protein
CBEI_RS13725	COG1187	pseudouridine synthase activity
CBEI_RS13740	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBEI_RS13740	COG2247	cell wall binding repeat
CBEI_RS13745	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS13750	COG1486	melibiose metabolic process
CBEI_RS13755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS13760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS13785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBEI_RS13810	COG0667	Aldo Keto reductase
CBEI_RS13830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CBEI_RS13835	COG0492	ferredoxin-NADP+ reductase activity
CBEI_RS13875	COG0454	-acetyltransferase
CBEI_RS13970	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CBEI_RS13975	COG0006	proline dipeptidase activity
CBEI_RS13980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS13980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS13995	COG1363	Peptidase, m42
CBEI_RS14035	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CBEI_RS14070	COG3973	AAA domain
CBEI_RS14080	COG2204	response regulator
CBEI_RS14085	COG1639	'signal transduction protein
CBEI_RS14090	COG4191	Histidine kinase
CBEI_RS14110	COG5002	protein histidine kinase activity
CBEI_RS14120	COG1733	regulation of RNA biosynthetic process
CBEI_RS14140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS14140	COG3711	transcriptional antiterminator
CBEI_RS14155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS14160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBEI_RS14180	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CBEI_RS14190	COG0714	Associated with various cellular activities
CBEI_RS14210	COG3831	ATPase activity
CBEI_RS14220	COG0439	Biotin carboxylase
CBEI_RS14225	COG0511	ligase activity, forming carbon-carbon bonds
CBEI_RS14230	COG1984	allophanate hydrolase subunit 2
CBEI_RS14235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CBEI_RS14240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBEI_RS14245	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CBEI_RS14250	COG4336	lyase activity
CBEI_RS14265	COG1522	sequence-specific DNA binding
CBEI_RS14305	COG0840	transmembrane signaling receptor activity
CBEI_RS14310	COG0488	(ABC) transporter
CBEI_RS14325	COG0494	nUDIX hydrolase
CBEI_RS14330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBEI_RS14340	COG0778	Nitroreductase
CBEI_RS14355	COG0561	phosphatase activity
CBEI_RS14360	COG0534	Mate efflux family protein
CBEI_RS14380	COG5002	protein histidine kinase activity
CBEI_RS14385	COG0840	transmembrane signaling receptor activity
CBEI_RS14390	COG1278	Cold shock
CBEI_RS14395	COG0039	L-malate dehydrogenase activity
CBEI_RS14420	COG1132	(ABC) transporter
CBEI_RS14425	COG1132	(ABC) transporter
CBEI_RS14475	COG3547	Transposase (IS116 IS110 IS902 family)
CBEI_RS14515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBEI_RS14540	COG2207	Transcriptional regulator
CBEI_RS14540	COG3708	Transcriptional regulator
CBEI_RS14560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBEI_RS14575	COG0519	Catalyzes the synthesis of GMP from XMP
CBEI_RS14605	COG1191	sigma factor activity
CBEI_RS14610	COG3469	chitinase activity
CBEI_RS14610	COG3325	Belongs to the glycosyl hydrolase 18 family
CBEI_RS14625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS14625	COG1263	PTS System
CBEI_RS14625	COG2190	(PTS) system
CBEI_RS14630	COG3711	transcriptional antiterminator
CBEI_RS14635	COG1309	transcriptional regulator
CBEI_RS14660	COG3384	dioxygenase
CBEI_RS14685	COG0745	RESPONSE REGULATOR receiver
CBEI_RS14690	COG2205	protein histidine kinase activity
CBEI_RS14720	COG2814	Major facilitator Superfamily
CBEI_RS14735	COG0572	uridine kinase
CBEI_RS14755	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS14755	COG2207	Transcriptional regulator
CBEI_RS14765	COG0596	Alpha beta hydrolase
CBEI_RS14775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBEI_RS14790	COG0583	DNA-binding transcription factor activity
CBEI_RS14800	COG1174	glycine betaine transport
CBEI_RS14870	COG1960	acyl-CoA dehydrogenase activity
CBEI_RS14875	COG0277	FAD linked oxidase domain protein
CBEI_RS14885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CBEI_RS14890	COG2086	electron transfer activity
CBEI_RS14895	COG0778	Nitroreductase
CBEI_RS14900	COG1113	amino acid transport
CBEI_RS14905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS14915	COG0395	ABC-type sugar transport system, permease component
CBEI_RS14935	COG2207	Transcriptional regulator
CBEI_RS14935	COG4753	response regulator
CBEI_RS14940	COG2972	Histidine kinase
CBEI_RS14950	COG5001	Diguanylate cyclase
CBEI_RS14960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS14960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS14965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS14980	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS14985	COG3715	PTS system
CBEI_RS14990	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS15040	COG0840	transmembrane signaling receptor activity
CBEI_RS15045	COG0025	NhaP-type Na H and K H
CBEI_RS15050	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS15075	COG0745	RESPONSE REGULATOR receiver
CBEI_RS15080	COG5002	protein histidine kinase activity
CBEI_RS15085	COG2814	Major facilitator Superfamily
CBEI_RS15090	COG1566	PFAM secretion protein HlyD family protein
CBEI_RS15110	COG1278	Cold shock
CBEI_RS15120	COG2186	Transcriptional regulator
CBEI_RS15125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBEI_RS15145	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CBEI_RS15150	COG3706	GGDEF domain
CBEI_RS15155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CBEI_RS15165	COG0038	chloride channel
CBEI_RS15175	COG0300	oxidoreductase activity
CBEI_RS15180	COG2323	membrane
CBEI_RS15195	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBEI_RS15205	COG3973	AAA domain
CBEI_RS15220	COG5002	protein histidine kinase activity
CBEI_RS15235	COG0840	transmembrane signaling receptor activity
CBEI_RS15240	COG0662	Cupin 2, conserved barrel domain protein
CBEI_RS15265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBEI_RS15270	COG0785	Cytochrome C biogenesis protein
CBEI_RS15280	COG1342	Belongs to the UPF0251 family
CBEI_RS15295	COG1575	Belongs to the MenA family. Type 1 subfamily
CBEI_RS15320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBEI_RS15325	COG0791	NLP P60 protein
CBEI_RS15330	COG2884	Cell division ATP-binding protein ftsE
CBEI_RS15335	COG2177	Part of the ABC transporter FtsEX involved in
CBEI_RS15345	COG0840	transmembrane signaling receptor activity
CBEI_RS15350	COG0785	Cytochrome C biogenesis protein
CBEI_RS15355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBEI_RS15390	COG5002	protein histidine kinase activity
CBEI_RS15395	COG0745	RESPONSE REGULATOR receiver
CBEI_RS15400	COG1007	ATP synthesis coupled electron transport
CBEI_RS15405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBEI_RS15410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CBEI_RS15420	COG0839	Belongs to the complex I subunit 6 family
CBEI_RS15425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBEI_RS15430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBEI_RS15435	COG0649	NAD binding
CBEI_RS15440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBEI_RS15445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBEI_RS15450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBEI_RS15465	COG1575	Belongs to the MenA family. Type 1 subfamily
CBEI_RS15470	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBEI_RS15480	COG0730	response to heat
CBEI_RS15490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBEI_RS15500	COG0309	Hydrogenase expression formation protein (HypE)
CBEI_RS15505	COG0409	Hydrogenase expression formation protein
CBEI_RS15515	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CBEI_RS15540	COG1151	hydroxylamine reductase activity
CBEI_RS15550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBEI_RS15555	COG1773	rubredoxin
CBEI_RS15555	COG0426	domain, Protein
CBEI_RS15560	COG0426	domain, Protein
CBEI_RS15565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBEI_RS15570	COG1151	hydroxylamine reductase activity
CBEI_RS15590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBEI_RS15610	COG0477	Major facilitator Superfamily
CBEI_RS15625	COG3655	Transcriptional regulator
CBEI_RS15645	COG0450	alkyl hydroperoxide reductase
CBEI_RS15655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBEI_RS15660	COG2738	Putative neutral zinc metallopeptidase
CBEI_RS15665	COG3588	fructose-bisphosphate aldolase
CBEI_RS15675	COG0726	polysaccharide deacetylase
CBEI_RS15700	COG0840	transmembrane signaling receptor activity
CBEI_RS15705	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBEI_RS15715	COG0488	(ABC) transporter
CBEI_RS15725	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CBEI_RS15730	COG5002	protein histidine kinase activity
CBEI_RS15735	COG0745	RESPONSE REGULATOR receiver
CBEI_RS15740	COG0348	domain, Protein
CBEI_RS15755	COG0778	Nitroreductase
CBEI_RS15770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBEI_RS15770	COG0723	plastoquinol--plastocyanin reductase activity
CBEI_RS15780	COG2119	membrane
CBEI_RS15785	COG1937	Protein conserved in bacteria
CBEI_RS15815	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS15840	COG3300	MHYT domain
CBEI_RS15840	COG5001	Diguanylate cyclase
CBEI_RS15855	COG0784	Response regulator, receiver
CBEI_RS15855	COG2205	protein histidine kinase activity
CBEI_RS15870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CBEI_RS15875	COG1733	regulation of RNA biosynthetic process
CBEI_RS15880	COG0778	Nitroreductase
CBEI_RS15890	COG1335	isochorismatase
CBEI_RS15910	COG0488	(ABC) transporter
CBEI_RS15920	COG0124	histidyl-tRNA synthetase
CBEI_RS15930	COG1132	(ABC) transporter
CBEI_RS15935	COG1132	(ABC) transporter
CBEI_RS15945	COG1129	ABC transporter
CBEI_RS15995	COG0484	heat shock protein binding
CBEI_RS16005	COG2409	Drug exporters of the RND superfamily
CBEI_RS16005	COG1033	growth of symbiont in host cell
CBEI_RS16065	COG0840	transmembrane signaling receptor activity
CBEI_RS16075	COG1079	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS16080	COG4603	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS16085	COG3845	ABC transporter
CBEI_RS16090	COG1744	ABC transporter substrate-binding protein PnrA-like
CBEI_RS16095	COG0813	purine-nucleoside phosphorylase activity
CBEI_RS16105	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CBEI_RS16110	COG0295	cytidine deaminase activity
CBEI_RS16115	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CBEI_RS16120	COG2188	Transcriptional regulator
CBEI_RS16135	COG0583	DNA-binding transcription factor activity
CBEI_RS16140	COG0667	Aldo Keto reductase
CBEI_RS16155	COG1733	regulation of RNA biosynthetic process
CBEI_RS16170	COG0693	protein deglycase activity
CBEI_RS16185	COG1309	transcriptional regulator
CBEI_RS16190	COG0534	Mate efflux family protein
CBEI_RS16205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBEI_RS16225	COG0210	DNA helicase
CBEI_RS16230	COG1111	helicase
CBEI_RS16230	COG1205	dead DEAH box helicase
CBEI_RS16285	COG0534	Mate efflux family protein
CBEI_RS16290	COG2207	Transcriptional regulator
CBEI_RS16300	COG0588	phosphoglycerate mutase activity
CBEI_RS16325	COG1309	transcriptional regulator
CBEI_RS16335	COG1794	racemase activity, acting on amino acids and derivatives
CBEI_RS16340	COG0583	DNA-binding transcription factor activity
CBEI_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS16355	COG0583	DNA-binding transcription factor activity
CBEI_RS16360	COG1073	alpha beta
CBEI_RS16365	COG0789	Transcriptional regulator
CBEI_RS16375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBEI_RS16375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBEI_RS16435	COG1819	glycosyl
CBEI_RS16440	COG3617	BRO family, N-terminal domain
CBEI_RS16445	COG2002	toxin-antitoxin pair type II binding
CBEI_RS16450	COG1484	DNA-dependent DNA replication
CBEI_RS16475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBEI_RS16515	COG1418	mRNA catabolic process
CBEI_RS16545	COG1027	Aspartate ammonia-lyase
CBEI_RS16550	COG0583	DNA-binding transcription factor activity
CBEI_RS16615	COG2177	Part of the ABC transporter FtsEX involved in
CBEI_RS16660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBEI_RS16665	COG1027	Aspartate ammonia-lyase
CBEI_RS16690	COG0586	Pfam SNARE associated Golgi protein
CBEI_RS16705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CBEI_RS16740	COG0673	inositol 2-dehydrogenase activity
CBEI_RS16745	COG1011	Hydrolase
CBEI_RS16750	COG0701	Predicted permease
CBEI_RS16795	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS16805	COG2190	(PTS) system
CBEI_RS16805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS16805	COG1263	PTS System
CBEI_RS16810	COG3711	transcriptional antiterminator
CBEI_RS16820	COG0531	amino acid
CBEI_RS16835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CBEI_RS16900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBEI_RS16905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBEI_RS16935	COG1132	(ABC) transporter
CBEI_RS16940	COG1132	(ABC) transporter
CBEI_RS16965	COG3963	phosphatidate phosphatase activity
CBEI_RS16980	COG1132	(ABC) transporter
CBEI_RS16985	COG1132	(ABC) transporter
CBEI_RS16990	COG0789	Transcriptional regulator
CBEI_RS17010	COG3706	GGDEF domain
CBEI_RS17015	COG1733	regulation of RNA biosynthetic process
CBEI_RS17020	COG1902	pentaerythritol trinitrate reductase activity
CBEI_RS17040	COG0840	transmembrane signaling receptor activity
CBEI_RS17065	COG1131	(ABC) transporter
CBEI_RS17075	COG1253	flavin adenine dinucleotide binding
CBEI_RS17095	COG1116	anion transmembrane transporter activity
CBEI_RS17100	COG4521	taurine ABC transporter
CBEI_RS17105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBEI_RS17150	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS17155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS17155	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS17160	COG2378	regulation of single-species biofilm formation
CBEI_RS17165	COG4335	DNA alkylation repair
CBEI_RS17170	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS17175	COG2033	superoxide reductase activity
CBEI_RS17180	COG2030	dehydratase
CBEI_RS17185	COG2610	gluconate transmembrane transporter activity
CBEI_RS17195	COG3290	protein histidine kinase activity
CBEI_RS17195	COG3829	transcription factor binding
CBEI_RS17210	COG1733	regulation of RNA biosynthetic process
CBEI_RS17215	COG0840	transmembrane signaling receptor activity
CBEI_RS17225	COG3850	Histidine kinase
CBEI_RS17225	COG5002	protein histidine kinase activity
CBEI_RS17230	COG0745	RESPONSE REGULATOR receiver
CBEI_RS17240	COG1011	Hydrolase
CBEI_RS17250	COG2239	Acts as a magnesium transporter
CBEI_RS17255	COG1914	H( )-stimulated, divalent metal cation uptake system
CBEI_RS17260	COG0772	Belongs to the SEDS family
CBEI_RS17265	COG1609	Transcriptional regulator
CBEI_RS17275	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS17310	COG2002	toxin-antitoxin pair type II binding
CBEI_RS17320	COG5002	protein histidine kinase activity
CBEI_RS17330	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CBEI_RS17445	COG2205	protein histidine kinase activity
CBEI_RS17445	COG0784	Response regulator, receiver
CBEI_RS17450	COG0745	RESPONSE REGULATOR receiver
CBEI_RS17450	COG2205	protein histidine kinase activity
CBEI_RS17450	COG4191	Histidine kinase
CBEI_RS17505	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS17505	COG2207	Transcriptional regulator
CBEI_RS17530	COG3878	Protein conserved in bacteria
CBEI_RS17560	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS17565	COG0583	DNA-binding transcription factor activity
CBEI_RS17580	COG2703	oxygen carrier activity
CBEI_RS17585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBEI_RS17615	COG1121	(ABC) transporter
CBEI_RS17625	COG0697	spore germination
CBEI_RS17630	COG2207	Transcriptional regulator
CBEI_RS17630	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS17635	COG0346	lactoylglutathione lyase activity
CBEI_RS17640	COG0110	maltose O-acetyltransferase activity
CBEI_RS17650	COG2207	Transcriptional regulator
CBEI_RS17650	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS17660	COG0662	Cupin 2, conserved barrel domain protein
CBEI_RS17660	COG2207	Transcriptional regulator
CBEI_RS17725	COG2207	Transcriptional regulator
CBEI_RS17735	COG0789	Transcriptional regulator
CBEI_RS17775	COG0500	methyltransferase
CBEI_RS17790	COG0583	DNA-binding transcription factor activity
CBEI_RS17795	COG0789	Transcriptional regulator
CBEI_RS17805	COG4191	Histidine kinase
CBEI_RS17815	COG2204	response regulator
CBEI_RS17820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBEI_RS17830	COG0726	polysaccharide deacetylase
CBEI_RS17865	COG2226	methyltransferase
CBEI_RS17870	COG0242	peptide deformylase activity
CBEI_RS17890	COG0840	transmembrane signaling receptor activity
CBEI_RS17925	COG0384	phenazine biosynthesis protein PhzF
CBEI_RS17930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBEI_RS17935	COG0277	FAD linked oxidase domain protein
CBEI_RS17940	COG1940	carbohydrate kinase activity
CBEI_RS17955	COG1175	transmembrane transport
CBEI_RS17965	COG2972	Histidine kinase
CBEI_RS17970	COG2197	response regulator
CBEI_RS17975	COG3279	Response regulator of the LytR AlgR family
CBEI_RS17990	COG0583	DNA-binding transcription factor activity
CBEI_RS18000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBEI_RS18015	COG0242	peptide deformylase activity
CBEI_RS18020	COG0656	L-ascorbic acid biosynthetic process
CBEI_RS18025	COG0640	Transcriptional regulator
CBEI_RS18040	COG0574	Belongs to the PEP-utilizing enzyme family
CBEI_RS18040	COG3848	Pyruvate phosphate dikinase
CBEI_RS18045	COG1940	carbohydrate kinase activity
CBEI_RS18075	COG2081	HI0933 family
CBEI_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS18115	COG3576	pyridoxamine 5-phosphate
CBEI_RS18125	COG1902	pentaerythritol trinitrate reductase activity
CBEI_RS18130	COG1733	regulation of RNA biosynthetic process
CBEI_RS18135	COG1349	DNA-binding transcription factor activity
CBEI_RS18145	COG0640	Transcriptional regulator
CBEI_RS18165	COG1125	glycine betaine transport
CBEI_RS18165	COG0517	IMP dehydrogenase activity
CBEI_RS18180	COG2873	o-acetylhomoserine
CBEI_RS18205	COG1032	radical SAM domain protein
CBEI_RS18235	COG3541	Predicted nucleotidyltransferase
CBEI_RS18245	COG1690	Belongs to the RtcB family
CBEI_RS18270	COG0138	bifunctional purine biosynthesis protein purh
CBEI_RS18285	COG5002	protein histidine kinase activity
CBEI_RS18285	COG3850	Histidine kinase
CBEI_RS18290	COG0745	RESPONSE REGULATOR receiver
CBEI_RS18315	COG3901	Regulator of nitric oxide reductase transcription
CBEI_RS18315	COG0348	domain, Protein
CBEI_RS18320	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CBEI_RS18320	COG3976	FMN-binding domain protein
CBEI_RS18330	COG1695	Transcriptional regulator
CBEI_RS18360	COG4977	sequence-specific DNA binding
CBEI_RS18380	COG0596	Alpha beta hydrolase
CBEI_RS18410	COG0583	DNA-binding transcription factor activity
CBEI_RS18420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBEI_RS18450	COG0789	Transcriptional regulator
CBEI_RS18455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CBEI_RS18475	COG2323	membrane
CBEI_RS18530	COG4257	antibiotic catabolic process
CBEI_RS18535	COG0024	Methionine aminopeptidase
CBEI_RS18540	COG1395	domain, Protein
CBEI_RS18570	COG1595	DNA-templated transcription, initiation
CBEI_RS18585	COG0840	transmembrane signaling receptor activity
CBEI_RS18590	COG2267	carboxylic ester hydrolase activity
CBEI_RS18610	COG0183	Belongs to the thiolase family
CBEI_RS18615	COG0583	DNA-binding transcription factor activity
CBEI_RS18625	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS18630	COG0789	Transcriptional regulator
CBEI_RS18635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CBEI_RS18640	COG0534	Mate efflux family protein
CBEI_RS18645	COG1846	Transcriptional regulator
CBEI_RS18665	COG3547	Transposase (IS116 IS110 IS902 family)
CBEI_RS18670	COG1013	pyruvate-flavodoxin oxidoreductase activity
CBEI_RS18675	COG0778	Nitroreductase
CBEI_RS18680	COG1309	transcriptional regulator
CBEI_RS18710	COG1309	transcriptional regulator
CBEI_RS18715	COG2271	Major facilitator Superfamily
CBEI_RS18720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS18755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBEI_RS18765	COG0706	membrane insertase activity
CBEI_RS18775	COG5002	protein histidine kinase activity
CBEI_RS18785	COG1876	peptidase activity
CBEI_RS18790	COG2205	protein histidine kinase activity
CBEI_RS18810	COG0745	RESPONSE REGULATOR receiver
CBEI_RS18820	COG0840	transmembrane signaling receptor activity
CBEI_RS18820	COG3290	protein histidine kinase activity
CBEI_RS18825	COG5599	Phosphatase
CBEI_RS18830	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CBEI_RS18840	COG1595	DNA-templated transcription, initiation
CBEI_RS18860	COG2801	Transposase and inactivated derivatives
CBEI_RS18885	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CBEI_RS18890	COG1136	(ABC) transporter
CBEI_RS18920	COG0577	efflux transmembrane transporter activity
CBEI_RS18920	COG1136	(ABC) transporter
CBEI_RS18935	COG1122	ATPase activity
CBEI_RS18945	COG0310	cobalt ion transport
CBEI_RS18980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBEI_RS18985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBEI_RS18990	COG4604	ABC transporter, ATP-binding protein
CBEI_RS19005	COG3706	GGDEF domain
CBEI_RS19010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CBEI_RS19020	COG0310	cobalt ion transport
CBEI_RS19025	COG1122	ATPase activity
CBEI_RS19060	COG0110	maltose O-acetyltransferase activity
CBEI_RS19090	COG3409	Peptidoglycan-binding domain 1 protein
CBEI_RS19125	COG1484	DNA-dependent DNA replication
CBEI_RS19165	COG1846	Transcriptional regulator
CBEI_RS19170	COG0546	phosphoglycolate phosphatase activity
CBEI_RS19210	COG3620	sequence-specific DNA binding
CBEI_RS19255	COG0277	FAD linked oxidase domain protein
CBEI_RS19260	COG1120	ATPase activity
CBEI_RS19265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBEI_RS19270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBEI_RS19285	COG1472	Belongs to the glycosyl hydrolase 3 family
CBEI_RS19290	COG2207	Transcriptional regulator
CBEI_RS19300	COG2190	(PTS) system
CBEI_RS19305	COG0561	phosphatase activity
CBEI_RS19325	COG1621	beta-fructofuranosidase activity
CBEI_RS19350	COG1216	Glycosyl transferase, family 2
CBEI_RS19365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBEI_RS19365	COG0493	'glutamate synthase
CBEI_RS19375	COG0840	transmembrane signaling receptor activity
CBEI_RS19415	COG0840	transmembrane signaling receptor activity
CBEI_RS19435	COG0746	molybdenum cofactor guanylyltransferase activity
CBEI_RS19440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBEI_RS19450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBEI_RS19455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CBEI_RS19460	COG1763	Mo-molybdopterin cofactor biosynthetic process
CBEI_RS19470	COG3383	formate dehydrogenase (NAD+) activity
CBEI_RS19480	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBEI_RS19485	COG5278	phosphoserine phosphatase activity
CBEI_RS19485	COG0840	transmembrane signaling receptor activity
CBEI_RS19495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBEI_RS19500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CBEI_RS19520	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS19530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS19535	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS19540	COG2188	Transcriptional regulator
CBEI_RS19545	COG2204	response regulator
CBEI_RS19550	COG3852	Histidine kinase
CBEI_RS19555	COG4670	ketone body catabolic process
CBEI_RS19560	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBEI_RS19565	COG2031	fatty acid transporter
CBEI_RS19575	COG0840	transmembrane signaling receptor activity
CBEI_RS19590	COG1129	ABC transporter
CBEI_RS19590	COG0842	Transport permease protein
CBEI_RS19595	COG3620	sequence-specific DNA binding
CBEI_RS19600	COG1461	Dihydroxyacetone kinase
CBEI_RS19610	COG0693	protein deglycase activity
CBEI_RS19640	COG4689	acetoacetate decarboxylase
CBEI_RS19660	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBEI_RS19680	COG0110	maltose O-acetyltransferase activity
CBEI_RS19700	COG3708	Transcriptional regulator
CBEI_RS19700	COG2207	Transcriptional regulator
CBEI_RS19705	COG2205	protein histidine kinase activity
CBEI_RS19725	COG1131	(ABC) transporter
CBEI_RS19745	COG1136	(ABC) transporter
CBEI_RS19750	COG2267	carboxylic ester hydrolase activity
CBEI_RS19755	COG1309	transcriptional regulator
CBEI_RS19760	COG0574	Belongs to the PEP-utilizing enzyme family
CBEI_RS19760	COG3848	Pyruvate phosphate dikinase
CBEI_RS19770	COG1309	transcriptional regulator
CBEI_RS19795	COG4585	Histidine kinase
CBEI_RS19800	COG2197	response regulator
CBEI_RS19815	COG5492	domain, Protein
CBEI_RS19815	COG3583	domain protein
CBEI_RS19815	COG1621	beta-fructofuranosidase activity
CBEI_RS19820	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS19825	COG3715	PTS system
CBEI_RS19830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS19830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS19835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS19835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS19840	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS19840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS19845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS19855	COG1653	transport
CBEI_RS19860	COG0395	ABC-type sugar transport system, permease component
CBEI_RS19865	COG4209	transmembrane transport
CBEI_RS19910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBEI_RS19915	COG1063	alcohol dehydrogenase
CBEI_RS19920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBEI_RS19935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBEI_RS19940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBEI_RS19955	COG2207	Transcriptional regulator
CBEI_RS19955	COG3708	Transcriptional regulator
CBEI_RS19980	COG2207	Transcriptional regulator
CBEI_RS19985	COG1028	Short-chain dehydrogenase reductase Sdr
CBEI_RS19990	COG0778	Nitroreductase
CBEI_RS19995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBEI_RS20005	COG0110	maltose O-acetyltransferase activity
CBEI_RS20035	COG1846	Transcriptional regulator
CBEI_RS20040	COG2814	Major facilitator Superfamily
CBEI_RS20050	COG2755	lipolytic protein G-D-S-L family
CBEI_RS20075	COG4191	Histidine kinase
CBEI_RS20115	COG2267	carboxylic ester hydrolase activity
CBEI_RS20195	COG1733	regulation of RNA biosynthetic process
CBEI_RS20200	COG0778	Nitroreductase
CBEI_RS20210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBEI_RS20215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CBEI_RS20225	COG0840	transmembrane signaling receptor activity
CBEI_RS20255	COG3620	sequence-specific DNA binding
CBEI_RS20265	COG0840	transmembrane signaling receptor activity
CBEI_RS20270	COG1404	Belongs to the peptidase S8 family
CBEI_RS20320	COG0277	FAD linked oxidase domain protein
CBEI_RS20335	COG1113	amino acid transport
CBEI_RS20340	COG0789	Transcriptional regulator
CBEI_RS20345	COG0667	Aldo Keto reductase
CBEI_RS20360	COG4608	Belongs to the ABC transporter superfamily
CBEI_RS20365	COG0444	Belongs to the ABC transporter superfamily
CBEI_RS20370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBEI_RS20375	COG0601	transmembrane transport
CBEI_RS20395	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS20420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBEI_RS20425	COG3708	Transcriptional regulator
CBEI_RS20425	COG2207	Transcriptional regulator
CBEI_RS20435	COG1253	flavin adenine dinucleotide binding
CBEI_RS20440	COG1396	sequence-specific DNA binding
CBEI_RS20465	COG2267	carboxylic ester hydrolase activity
CBEI_RS20470	COG2226	methyltransferase
CBEI_RS20475	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CBEI_RS20500	COG4565	transcriptional regulatory protein
CBEI_RS20505	COG3290	protein histidine kinase activity
CBEI_RS20510	COG3426	butyrate kinase activity
CBEI_RS20520	COG0281	malic enzyme
CBEI_RS20530	COG1522	sequence-specific DNA binding
CBEI_RS20540	COG0840	transmembrane signaling receptor activity
CBEI_RS20545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBEI_RS20550	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBEI_RS20555	COG2204	response regulator
CBEI_RS20560	COG0784	Response regulator, receiver
CBEI_RS20560	COG2205	protein histidine kinase activity
CBEI_RS20560	COG5002	protein histidine kinase activity
CBEI_RS20565	COG0840	transmembrane signaling receptor activity
CBEI_RS20575	COG0643	Histidine kinase
CBEI_RS20575	COG2198	Histidine kinase
CBEI_RS20580	COG2201	protein-glutamate methylesterase activity
CBEI_RS20585	COG0561	phosphatase activity
CBEI_RS20590	COG1472	Belongs to the glycosyl hydrolase 3 family
CBEI_RS20595	COG1388	LysM domain
CBEI_RS20595	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBEI_RS20600	COG0697	spore germination
CBEI_RS20615	COG1924	4 iron, 4 sulfur cluster binding
CBEI_RS20620	COG0531	amino acid
CBEI_RS20625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBEI_RS20640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBEI_RS20650	COG4129	membrane
CBEI_RS20655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBEI_RS20660	COG1486	melibiose metabolic process
CBEI_RS20665	COG3394	polysaccharide catabolic process
CBEI_RS20685	COG1013	pyruvate-flavodoxin oxidoreductase activity
CBEI_RS20690	COG0674	pyruvate-flavodoxin oxidoreductase activity
CBEI_RS20690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CBEI_RS20695	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CBEI_RS20710	COG4820	ethanolamine utilization protein (EutJ)
CBEI_RS20715	COG4869	propanediol catabolic process
CBEI_RS20730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBEI_RS20735	COG4565	transcriptional regulatory protein
CBEI_RS20755	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CBEI_RS20780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CBEI_RS20785	COG1882	Formate acetyltransferase
CBEI_RS20815	COG2252	PERMEase
CBEI_RS20835	COG1971	Probably functions as a manganese efflux pump
CBEI_RS20855	COG5566	PFAM Mor transcription activator
CBEI_RS20860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS20865	COG0840	transmembrane signaling receptor activity
CBEI_RS20875	COG3963	phosphatidate phosphatase activity
CBEI_RS20890	COG1904	glucuronate isomerase
CBEI_RS20895	COG0246	Mannitol dehydrogenase
CBEI_RS20900	COG1312	Catalyzes the dehydration of D-mannonate
CBEI_RS20905	COG1802	Transcriptional regulator
CBEI_RS20910	COG0840	transmembrane signaling receptor activity
CBEI_RS20920	COG0531	amino acid
CBEI_RS20925	COG1403	HNH endonuclease
CBEI_RS20935	COG0371	Dehydrogenase
CBEI_RS20945	COG1983	PspC domain protein
CBEI_RS20950	COG0129	dihydroxy-acid dehydratase activity
CBEI_RS20955	COG2186	Transcriptional regulator
CBEI_RS20960	COG0531	amino acid
CBEI_RS20970	COG2814	Major facilitator Superfamily
CBEI_RS20975	COG1566	PFAM secretion protein HlyD family protein
CBEI_RS20980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBEI_RS20985	COG5002	protein histidine kinase activity
CBEI_RS20990	COG0745	RESPONSE REGULATOR receiver
CBEI_RS21010	COG1321	iron dependent repressor
CBEI_RS21015	COG1733	regulation of RNA biosynthetic process
CBEI_RS21060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CBEI_RS21075	COG0512	Glutamine amidotransferase of anthranilate synthase
CBEI_RS21075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBEI_RS21080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBEI_RS21085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CBEI_RS21090	COG0071	Belongs to the small heat shock protein (HSP20) family
CBEI_RS21100	COG2211	Major facilitator Superfamily
CBEI_RS21105	COG3507	Belongs to the glycosyl hydrolase 43 family
CBEI_RS21110	COG0129	dihydroxy-acid dehydratase activity
CBEI_RS21115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBEI_RS21120	COG1414	Transcriptional regulator
CBEI_RS21125	COG0789	Transcriptional regulator
CBEI_RS21135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CBEI_RS21140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CBEI_RS21150	COG1523	belongs to the glycosyl hydrolase 13 family
CBEI_RS21165	COG2267	carboxylic ester hydrolase activity
CBEI_RS21180	COG0813	purine-nucleoside phosphorylase activity
CBEI_RS21190	COG1079	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS21195	COG4603	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS21200	COG3845	ABC transporter
CBEI_RS21205	COG1744	ABC transporter substrate-binding protein PnrA-like
CBEI_RS21210	COG1609	Transcriptional regulator
CBEI_RS21220	COG0436	Aminotransferase
CBEI_RS21225	COG1522	sequence-specific DNA binding
CBEI_RS21235	COG0542	response to heat
CBEI_RS21240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBEI_RS21245	COG1982	Orn Lys Arg decarboxylase major
CBEI_RS21270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS21270	COG1263	PTS System
CBEI_RS21285	COG5278	phosphoserine phosphatase activity
CBEI_RS21285	COG0840	transmembrane signaling receptor activity
CBEI_RS21290	COG0789	Transcriptional regulator
CBEI_RS21305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CBEI_RS21305	COG2199	diguanylate cyclase activity
CBEI_RS21315	COG1136	(ABC) transporter
CBEI_RS21320	COG2205	protein histidine kinase activity
CBEI_RS21325	COG0745	RESPONSE REGULATOR receiver
CBEI_RS21330	COG0765	amino acid transport
CBEI_RS21335	COG0765	amino acid transport
CBEI_RS21340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS21350	COG0784	Response regulator, receiver
CBEI_RS21355	COG5002	protein histidine kinase activity
CBEI_RS21370	COG1396	sequence-specific DNA binding
CBEI_RS21380	COG2201	protein-glutamate methylesterase activity
CBEI_RS21385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CBEI_RS21395	COG2198	Histidine kinase
CBEI_RS21395	COG0643	Histidine kinase
CBEI_RS21400	COG0835	chemotaxis
CBEI_RS21410	COG2895	sulfate adenylyltransferase (ATP) activity
CBEI_RS21415	COG0175	sulfate reduction
CBEI_RS21430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBEI_RS21435	COG4208	sulfate ABC transporter
CBEI_RS21445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBEI_RS21450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBEI_RS21475	COG0538	isocitrate dehydrogenase activity
CBEI_RS21495	COG0493	'glutamate synthase
CBEI_RS21500	COG0067	glutamate synthase
CBEI_RS21500	COG0070	glutamate synthase
CBEI_RS21500	COG0069	glutamate synthase activity
CBEI_RS21515	COG0527	aspartate kinase activity
CBEI_RS21520	COG0586	Pfam SNARE associated Golgi protein
CBEI_RS21565	COG1459	type II secretion system
CBEI_RS21570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBEI_RS21575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBEI_RS21595	COG0217	transcriptional regulatory protein
CBEI_RS21600	COG1739	Uncharacterized protein family UPF0029
CBEI_RS21605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBEI_RS21620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBEI_RS21635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CBEI_RS21645	COG0105	UTP biosynthetic process
CBEI_RS21650	COG1254	Belongs to the acylphosphatase family
CBEI_RS21655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CBEI_RS21665	COG1215	transferase activity, transferring glycosyl groups
CBEI_RS21685	COG0561	phosphatase activity
CBEI_RS21690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBEI_RS21700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBEI_RS21720	COG4786	Flagellar basal body rod
CBEI_RS21725	COG4786	Flagellar basal body rod
CBEI_RS21735	COG1191	sigma factor activity
CBEI_RS21745	COG0455	bacterial-type flagellum organization
CBEI_RS21750	COG1419	protein localization to endoplasmic reticulum
CBEI_RS21755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBEI_RS21760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBEI_RS21770	COG1338	Plays a role in the flagellum-specific transport system
CBEI_RS21785	COG1582	Flagellar protein (FlbD)
CBEI_RS21790	COG4786	Flagellar basal body rod
CBEI_RS21800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CBEI_RS21815	COG1157	protein secretion by the type III secretion system
CBEI_RS21825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBEI_RS21835	COG1677	Flagellar hook-basal body complex protein FliE
CBEI_RS21845	COG1815	bacterial-type flagellum-dependent cell motility
CBEI_RS21850	COG1360	Flagellar Motor Protein
CBEI_RS21855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CBEI_RS21860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CBEI_RS21880	COG2089	acid synthase
CBEI_RS21885	COG2030	dehydratase
CBEI_RS21895	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CBEI_RS21900	COG1086	Polysaccharide biosynthesis protein
CBEI_RS21910	COG2604	Protein of unknown function DUF115
CBEI_RS21935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CBEI_RS21945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CBEI_RS21965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CBEI_RS21970	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CBEI_RS21980	COG1256	bacterial-type flagellum assembly
CBEI_RS21980	COG4786	Flagellar basal body rod
CBEI_RS22000	COG1776	CheC inhibitor of MCP methylation
CBEI_RS22000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBEI_RS22005	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBEI_RS22015	COG2201	protein-glutamate methylesterase activity
CBEI_RS22020	COG1776	CheC inhibitor of MCP methylation
CBEI_RS22025	COG0643	Histidine kinase
CBEI_RS22025	COG2198	Histidine kinase
CBEI_RS22035	COG2201	protein-glutamate methylesterase activity
CBEI_RS22045	COG0835	chemotaxis
CBEI_RS22070	COG0436	Aminotransferase
CBEI_RS22085	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBEI_RS22090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBEI_RS22095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBEI_RS22095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CBEI_RS22105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CBEI_RS22110	COG0187	DNA topoisomerase II activity
CBEI_RS22115	COG1215	transferase activity, transferring glycosyl groups
CBEI_RS22120	COG0705	Rhomboid family
CBEI_RS22120	COG0457	Tetratricopeptide repeat
CBEI_RS22125	COG1164	Oligoendopeptidase f
CBEI_RS22140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBEI_RS22145	COG1696	Membrane protein involved in D-alanine export
CBEI_RS22155	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CBEI_RS22160	COG1121	(ABC) transporter
CBEI_RS22165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBEI_RS22170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBEI_RS22170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBEI_RS22175	COG0028	Belongs to the TPP enzyme family
CBEI_RS22175	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CBEI_RS22185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBEI_RS22200	COG1131	(ABC) transporter
CBEI_RS22205	COG1725	Transcriptional regulator
CBEI_RS22225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBEI_RS22230	COG2508	Transcriptional regulator
CBEI_RS22235	COG0765	amino acid transport
CBEI_RS22240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS22250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBEI_RS22280	COG2207	Transcriptional regulator
CBEI_RS22285	COG1486	melibiose metabolic process
CBEI_RS22295	COG1533	DNA photolyase activity
CBEI_RS22340	COG1515	deoxyribonuclease V activity
CBEI_RS22350	COG5444	nuclease activity
CBEI_RS22505	COG0484	heat shock protein binding
CBEI_RS22535	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CBEI_RS22540	COG1982	Orn Lys Arg decarboxylase major
CBEI_RS22545	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CBEI_RS22580	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CBEI_RS22585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBEI_RS22590	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CBEI_RS22610	COG0288	reversible hydration of carbon dioxide
CBEI_RS22615	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS22625	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS22635	COG2972	Histidine kinase
CBEI_RS22640	COG4753	response regulator
CBEI_RS22640	COG4753	response regulator
CBEI_RS22640	COG2207	Transcriptional regulator
CBEI_RS22640	COG2207	Transcriptional regulator
CBEI_RS22645	COG4211	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS22660	COG0840	transmembrane signaling receptor activity
CBEI_RS22670	COG4974	Belongs to the 'phage' integrase family
CBEI_RS22675	COG0840	transmembrane signaling receptor activity
CBEI_RS22700	COG0395	ABC-type sugar transport system, permease component
CBEI_RS22705	COG1175	transmembrane transport
CBEI_RS22715	COG2207	Transcriptional regulator
CBEI_RS22720	COG1307	EDD domain protein, DegV family
CBEI_RS22725	COG4214	carbohydrate transport
CBEI_RS22735	COG4213	ABC transporter substrate-binding protein
CBEI_RS22750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBEI_RS22770	COG2160	L-arabinose isomerase activity
CBEI_RS22775	COG2972	Histidine kinase
CBEI_RS22780	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS22785	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS22790	COG1129	ABC transporter
CBEI_RS22795	COG1879	ABC-type sugar transport system periplasmic component
CBEI_RS22805	COG2207	Transcriptional regulator
CBEI_RS22805	COG4753	response regulator
CBEI_RS22815	COG0840	transmembrane signaling receptor activity
CBEI_RS22820	COG0561	phosphatase activity
CBEI_RS22825	COG2188	Transcriptional regulator
CBEI_RS22835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CBEI_RS22835	COG1796	DNA polymerase
CBEI_RS22860	COG0514	ATP-dependent DNA helicase (RecQ)
CBEI_RS22865	COG3835	regulator
CBEI_RS22875	COG1929	Belongs to the glycerate kinase type-1 family
CBEI_RS22880	COG2610	gluconate transmembrane transporter activity
CBEI_RS22885	COG0426	domain, Protein
CBEI_RS22895	COG0426	domain, Protein
CBEI_RS22900	COG5002	protein histidine kinase activity
CBEI_RS22915	COG0352	thiamine-phosphate diphosphorylase activity
CBEI_RS22920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CBEI_RS22930	COG0351	phosphomethylpyrimidine kinase
CBEI_RS22930	COG0352	thiamine-phosphate diphosphorylase activity
CBEI_RS22940	COG0348	domain, Protein
CBEI_RS22940	COG3901	Regulator of nitric oxide reductase transcription
CBEI_RS22950	COG5002	protein histidine kinase activity
CBEI_RS22955	COG0745	RESPONSE REGULATOR receiver
CBEI_RS22965	COG1760	l-serine dehydratase
CBEI_RS22985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBEI_RS22990	COG1120	ATPase activity
CBEI_RS23010	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBEI_RS23020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CBEI_RS23025	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CBEI_RS23030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CBEI_RS23040	COG2323	membrane
CBEI_RS23050	COG0137	argininosuccinate synthase activity
CBEI_RS23055	COG0165	Argininosuccinate lyase
CBEI_RS23060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBEI_RS23065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBEI_RS23070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBEI_RS23075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBEI_RS23080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBEI_RS23085	COG0322	excinuclease ABC activity
CBEI_RS23100	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS23110	COG1113	amino acid transport
CBEI_RS23115	COG2271	Major facilitator Superfamily
CBEI_RS23135	COG1263	PTS System
CBEI_RS23135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS23145	COG3711	transcriptional antiterminator
CBEI_RS23150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS23155	COG2971	BadF BadG BcrA BcrD
CBEI_RS23160	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS23165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS23170	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS23170	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS23180	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CBEI_RS23185	COG1960	acyl-CoA dehydrogenase activity
CBEI_RS23190	COG4670	ketone body catabolic process
CBEI_RS23195	COG1024	Enoyl-CoA hydratase
CBEI_RS23200	COG2814	Major facilitator Superfamily
CBEI_RS23205	COG1082	Xylose isomerase domain protein TIM barrel
CBEI_RS23210	COG0673	inositol 2-dehydrogenase activity
CBEI_RS23220	COG3718	enzyme involved in inositol metabolism
CBEI_RS23225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS23230	COG0191	fructose-bisphosphate aldolase activity
CBEI_RS23240	COG1349	DNA-binding transcription factor activity
CBEI_RS23245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBEI_RS23250	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS23250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS23255	COG2222	sugar isomerase
CBEI_RS23260	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS23265	COG3715	PTS system
CBEI_RS23280	COG2188	Transcriptional regulator
CBEI_RS23285	COG0363	glucosamine-6-phosphate deaminase activity
CBEI_RS23290	COG2188	Transcriptional regulator
CBEI_RS23305	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS23320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CBEI_RS23325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBEI_RS23330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBEI_RS23335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBEI_RS23340	COG1605	Chorismate mutase
CBEI_RS23340	COG0077	Prephenate dehydratase
CBEI_RS23345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBEI_RS23350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBEI_RS23355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBEI_RS23360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CBEI_RS23365	COG4512	PFAM Accessory gene regulator B
CBEI_RS23375	COG3279	Response regulator of the LytR AlgR family
CBEI_RS23385	COG1132	(ABC) transporter
CBEI_RS23395	COG4152	abc transporter atp-binding protein
CBEI_RS23420	COG0495	leucyl-tRNA aminoacylation
CBEI_RS23425	COG0745	RESPONSE REGULATOR receiver
CBEI_RS23430	COG5002	protein histidine kinase activity
CBEI_RS23445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBEI_RS23450	COG0717	Belongs to the dCTP deaminase family
CBEI_RS23485	COG2357	RelA SpoT domain protein
CBEI_RS23495	COG0840	transmembrane signaling receptor activity
CBEI_RS23510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBEI_RS23520	COG3426	butyrate kinase activity
CBEI_RS23550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBEI_RS23555	COG2865	translation initiation factor activity
CBEI_RS23560	COG2199	diguanylate cyclase activity
CBEI_RS23560	COG2203	Gaf domain
CBEI_RS23565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBEI_RS23570	COG0673	inositol 2-dehydrogenase activity
CBEI_RS23575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBEI_RS23595	COG5002	protein histidine kinase activity
CBEI_RS23595	COG3850	Histidine kinase
CBEI_RS23600	COG0745	RESPONSE REGULATOR receiver
CBEI_RS23625	COG1216	Glycosyl transferase, family 2
CBEI_RS23625	COG1442	glycosyl transferase family 8
CBEI_RS23630	COG3475	LICD family
CBEI_RS23635	COG1442	glycosyl transferase family 8
CBEI_RS23635	COG1216	Glycosyl transferase, family 2
CBEI_RS23645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS23655	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS23665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS23675	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS23680	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS23680	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS23690	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS23695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBEI_RS23705	COG1737	Transcriptional regulator
CBEI_RS23710	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CBEI_RS23715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS23725	COG1609	Transcriptional regulator
CBEI_RS23730	COG2814	Major facilitator Superfamily
CBEI_RS23735	COG0561	phosphatase activity
CBEI_RS23760	COG1904	glucuronate isomerase
CBEI_RS23765	COG0246	Mannitol dehydrogenase
CBEI_RS23770	COG1312	Catalyzes the dehydration of D-mannonate
CBEI_RS23775	COG1802	Transcriptional regulator
CBEI_RS23785	COG0701	Predicted permease
CBEI_RS23805	COG0741	lytic transglycosylase activity
CBEI_RS23810	COG1368	sulfuric ester hydrolase activity
CBEI_RS23815	COG0803	Belongs to the bacterial solute-binding protein 9 family
CBEI_RS23820	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS23825	COG1486	melibiose metabolic process
CBEI_RS23830	COG1131	(ABC) transporter
CBEI_RS23845	COG1472	Belongs to the glycosyl hydrolase 3 family
CBEI_RS23860	COG2972	Histidine kinase
CBEI_RS23885	COG0840	transmembrane signaling receptor activity
CBEI_RS23890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CBEI_RS23900	COG1447	Phosphotransferase system cellobiose-specific component IIA
CBEI_RS23905	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS23905	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS23935	COG1309	transcriptional regulator
CBEI_RS23945	COG4750	Nucleotidyl transferase
CBEI_RS23965	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBEI_RS23970	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBEI_RS23980	COG3706	GGDEF domain
CBEI_RS23985	COG1737	Transcriptional regulator
CBEI_RS23990	COG1737	Transcriptional regulator
CBEI_RS23995	COG1486	melibiose metabolic process
CBEI_RS24000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS24000	COG1263	PTS System
CBEI_RS24010	COG0463	Glycosyl transferase, family 2
CBEI_RS24010	COG0457	Tetratricopeptide repeat
CBEI_RS24020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBEI_RS24035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBEI_RS24055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CBEI_RS24075	COG0584	glycerophosphoryl diester phosphodiesterase
CBEI_RS24095	COG0840	transmembrane signaling receptor activity
CBEI_RS24115	COG1136	(ABC) transporter
CBEI_RS24115	COG0577	efflux transmembrane transporter activity
CBEI_RS24130	COG1442	glycosyl transferase family 8
CBEI_RS24130	COG1216	Glycosyl transferase, family 2
CBEI_RS24145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBEI_RS24160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBEI_RS24165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CBEI_RS24170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBEI_RS24175	COG4464	protein tyrosine phosphatase activity
CBEI_RS24180	COG0489	protein tyrosine kinase activity
CBEI_RS24185	COG3944	biosynthesis protein
CBEI_RS24190	COG0628	permease
CBEI_RS24195	COG0791	NLP P60 protein
CBEI_RS24220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBEI_RS24225	COG1134	teichoic acid transport
CBEI_RS24230	COG1682	transport, permease protein
CBEI_RS24235	COG1091	dTDP-4-dehydrorhamnose reductase activity
CBEI_RS24245	COG1088	dTDP-glucose 4,6-dehydratase activity
CBEI_RS24330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CBEI_RS24335	COG0840	transmembrane signaling receptor activity
CBEI_RS24340	COG3459	Glycosyltransferase 36 associated
CBEI_RS24345	COG1362	aminopeptidase activity
CBEI_RS24355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBEI_RS24360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CBEI_RS24370	COG1126	abc transporter atp-binding protein
CBEI_RS24375	COG0765	amino acid transport
CBEI_RS24380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS24385	COG3973	AAA domain
CBEI_RS24390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBEI_RS24405	COG0681	Belongs to the peptidase S26 family
CBEI_RS24410	COG0019	diaminopimelate decarboxylase activity
CBEI_RS24430	COG0840	transmembrane signaling receptor activity
CBEI_RS24445	COG0436	Aminotransferase
CBEI_RS24460	COG2188	Transcriptional regulator
CBEI_RS24465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS24470	COG2222	sugar isomerase
CBEI_RS24475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS24480	COG2608	mercury ion transmembrane transporter activity
CBEI_RS24490	COG1937	Protein conserved in bacteria
CBEI_RS24495	COG2190	(PTS) system
CBEI_RS24495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS24495	COG1263	PTS System
CBEI_RS24505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS24505	COG1263	PTS System
CBEI_RS24515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CBEI_RS24515	COG2199	diguanylate cyclase activity
CBEI_RS24520	COG1473	amidohydrolase
CBEI_RS24525	COG1266	CAAX protease self-immunity
CBEI_RS24540	COG0745	RESPONSE REGULATOR receiver
CBEI_RS24545	COG2205	protein histidine kinase activity
CBEI_RS24545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBEI_RS24565	COG2703	oxygen carrier activity
CBEI_RS24570	COG0745	RESPONSE REGULATOR receiver
CBEI_RS24575	COG4999	Histidine kinase
CBEI_RS24575	COG3850	Histidine kinase
CBEI_RS24575	COG3437	response regulator, receiver
CBEI_RS24575	COG2205	protein histidine kinase activity
CBEI_RS24580	COG0840	transmembrane signaling receptor activity
CBEI_RS24585	COG0835	chemotaxis
CBEI_RS24590	COG0840	transmembrane signaling receptor activity
CBEI_RS24595	COG2201	protein-glutamate methylesterase activity
CBEI_RS24605	COG2197	response regulator
CBEI_RS24610	COG2201	protein-glutamate methylesterase activity
CBEI_RS24620	COG0840	transmembrane signaling receptor activity
CBEI_RS24625	COG0643	Histidine kinase
CBEI_RS24625	COG2198	Histidine kinase
CBEI_RS24630	COG1360	Flagellar Motor Protein
CBEI_RS24635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CBEI_RS24640	COG0840	transmembrane signaling receptor activity
CBEI_RS24645	COG2723	6-phospho-beta-galactosidase activity
CBEI_RS24650	COG3546	catalase activity
CBEI_RS24660	COG2188	Transcriptional regulator
CBEI_RS24665	COG4948	Mandelate Racemase Muconate Lactonizing
CBEI_RS24670	COG2190	(PTS) system
CBEI_RS24670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS24670	COG1263	PTS System
CBEI_RS24675	COG2746	aminoglycoside 3-N-acetyltransferase activity
CBEI_RS24680	COG2207	Transcriptional regulator
CBEI_RS24685	COG0673	inositol 2-dehydrogenase activity
CBEI_RS24690	COG1082	Xylose isomerase domain protein TIM barrel
CBEI_RS24700	COG4948	Mandelate Racemase Muconate Lactonizing
CBEI_RS24705	COG2190	(PTS) system
CBEI_RS24705	COG1263	PTS System
CBEI_RS24705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS24710	COG1486	melibiose metabolic process
CBEI_RS24715	COG1737	Transcriptional regulator
CBEI_RS24730	COG0469	pyruvate kinase activity
CBEI_RS24750	COG1481	regulation of sporulation
CBEI_RS24755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CBEI_RS24760	COG1660	Displays ATPase and GTPase activities
CBEI_RS24765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CBEI_RS24770	COG0322	excinuclease ABC activity
CBEI_RS24775	COG0768	penicillin binding
CBEI_RS24785	COG1716	ATPase activity
CBEI_RS24795	COG0556	nucleotide-excision repair
CBEI_RS24805	COG3409	Peptidoglycan-binding domain 1 protein
CBEI_RS24805	COG0793	Belongs to the peptidase S41A family
CBEI_RS24810	COG2177	Part of the ABC transporter FtsEX involved in
CBEI_RS24815	COG2884	Cell division ATP-binding protein ftsE
CBEI_RS24820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CBEI_RS24825	COG3958	Transketolase
CBEI_RS24830	COG3959	Transketolase, thiamine diphosphate binding domain
CBEI_RS24835	COG2337	Toxic component of a toxin-antitoxin (TA) module
CBEI_RS24850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CBEI_RS24850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBEI_RS24855	COG0736	holo-[acyl-carrier-protein] synthase activity
CBEI_RS24865	COG0629	single-stranded DNA binding
CBEI_RS24870	COG1295	ribonuclease BN
CBEI_RS24890	COG1199	ATP-dependent helicase activity
CBEI_RS24900	COG2002	toxin-antitoxin pair type II binding
CBEI_RS24905	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CBEI_RS24910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CBEI_RS24930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBEI_RS24935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CBEI_RS24960	COG1546	Belongs to the CinA family
CBEI_RS24960	COG1058	Belongs to the CinA family
CBEI_RS24965	COG1940	carbohydrate kinase activity
CBEI_RS24975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBEI_RS25020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBEI_RS25065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CBEI_RS25070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CBEI_RS25080	COG0058	SHG alpha-glucan phosphorylase activity
CBEI_RS25085	COG0297	glycogen (starch) synthase activity
CBEI_RS25125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBEI_RS25130	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS25135	COG3715	PTS system
CBEI_RS25140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS25140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS25145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS25145	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBEI_RS25150	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS25150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS25155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CBEI_RS25160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBEI_RS25165	COG0840	transmembrane signaling receptor activity
CBEI_RS25170	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
CBEI_RS25190	COG1846	Transcriptional regulator
CBEI_RS25195	COG2814	Major facilitator Superfamily
CBEI_RS25210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBEI_RS25215	COG4166	transmembrane transport
CBEI_RS25220	COG4608	Belongs to the ABC transporter superfamily
CBEI_RS25225	COG0444	Belongs to the ABC transporter superfamily
CBEI_RS25230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBEI_RS25235	COG0601	transmembrane transport
CBEI_RS25240	COG1454	alcohol dehydrogenase
CBEI_RS25250	COG2909	trisaccharide binding
CBEI_RS25255	COG1012	belongs to the aldehyde dehydrogenase family
CBEI_RS25260	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CBEI_RS25265	COG1177	transmembrane transport
CBEI_RS25270	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBEI_RS25275	COG3842	ATPase activity
CBEI_RS25285	COG0347	Belongs to the P(II) protein family
CBEI_RS25330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CBEI_RS25335	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CBEI_RS25345	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBEI_RS25355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBEI_RS25370	COG2201	protein-glutamate methylesterase activity
CBEI_RS25375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CBEI_RS25380	COG1970	mechanosensitive ion channel activity
CBEI_RS25385	COG2207	Transcriptional regulator
CBEI_RS25385	COG4753	response regulator
CBEI_RS25400	COG0840	transmembrane signaling receptor activity
CBEI_RS25410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBEI_RS25415	COG1129	ABC transporter
CBEI_RS25425	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBEI_RS25435	COG3507	Belongs to the glycosyl hydrolase 43 family
CBEI_RS25445	COG1472	Belongs to the glycosyl hydrolase 3 family
CBEI_RS25450	COG1917	Cupin 2, conserved barrel domain protein
CBEI_RS25450	COG4977	sequence-specific DNA binding
CBEI_RS25460	COG1263	PTS System
CBEI_RS25460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS25465	COG1486	melibiose metabolic process
CBEI_RS25475	COG2814	Major facilitator Superfamily
CBEI_RS25485	COG2190	(PTS) system
CBEI_RS25485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS25485	COG1263	PTS System
CBEI_RS25495	COG1486	melibiose metabolic process
CBEI_RS25585	COG4974	Belongs to the 'phage' integrase family
CBEI_RS25595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBEI_RS25600	COG2186	Transcriptional regulator
CBEI_RS25610	COG1346	cytolysis
CBEI_RS25620	COG0590	tRNA wobble adenosine to inosine editing
CBEI_RS25625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBEI_RS25630	COG1621	beta-fructofuranosidase activity
CBEI_RS25635	COG1609	Transcriptional regulator
CBEI_RS25640	COG1263	PTS System
CBEI_RS25640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS25675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CBEI_RS25675	COG1263	PTS System
CBEI_RS25710	COG5002	protein histidine kinase activity
CBEI_RS25710	COG3850	Histidine kinase
CBEI_RS25725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBEI_RS25735	COG0513	Belongs to the DEAD box helicase family
CBEI_RS25745	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CBEI_RS25745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CBEI_RS25750	COG0617	tRNA 3'-terminal CCA addition
CBEI_RS25755	COG0347	Belongs to the P(II) protein family
CBEI_RS25760	COG0004	ammonium transporteR
CBEI_RS25770	COG0659	secondary active sulfate transmembrane transporter activity
CBEI_RS25775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBEI_RS25800	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CBEI_RS25805	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CBEI_RS25815	COG0683	leucine binding
CBEI_RS25850	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CBEI_RS25865	COG1959	2 iron, 2 sulfur cluster binding
CBEI_RS25880	COG1960	acyl-CoA dehydrogenase activity
CBEI_RS25885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBEI_RS25890	COG2814	Major facilitator Superfamily
CBEI_RS25895	COG0840	transmembrane signaling receptor activity
CBEI_RS25900	COG0653	protein targeting
CBEI_RS25905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CBEI_RS25930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CBEI_RS25935	COG1404	Belongs to the peptidase S8 family
CBEI_RS26010	COG2081	HI0933 family
CBEI_RS26025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBEI_RS26030	COG0281	malic enzyme
CBEI_RS26040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CBEI_RS26050	COG0305	Participates in initiation and elongation during chromosome replication
CBEI_RS26055	COG1067	ATP-dependent peptidase activity
CBEI_RS26055	COG0470	DNA polymerase III
CBEI_RS26060	COG0359	binds to the 23S rRNA
CBEI_RS26065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CBEI_RS26075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBEI_RS26080	COG0629	single-stranded DNA binding
CBEI_RS26085	COG0360	Binds together with S18 to 16S ribosomal RNA
CBEI_RS26095	COG0668	transmembrane transport
CBEI_RS26110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CBEI_RS26125	COG1475	DNA binding
CBEI_RS26130	COG1192	Involved in chromosome partitioning
CBEI_RS26135	COG1475	DNA binding
CBEI_RS26140	COG0357	Ribosomal RNA small subunit methyltransferase G
CBEI_RS26145	COG0445	tRNA wobble uridine modification
CBEI_RS26150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBEI_RS26155	COG1847	R3H domain protein
CBEI_RS26165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CBEI_RS26170	COG0594	ribonuclease P activity
CBEI_RS26175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBEI_RS26245	COG1396	sequence-specific DNA binding
CBEI_RS26255	COG2801	Transposase and inactivated derivatives
CBEI_RS26280	COG3716	PTS system mannose fructose sorbose family IID component
CBEI_RS26370	COG1216	Glycosyl transferase, family 2
CBEI_RS26370	COG0438	transferase activity, transferring glycosyl groups
CBEI_RS26375	COG5002	protein histidine kinase activity