locus-tag	class	description
DRB99_RS00015	ENOG4105EJ9	Membrane
DRB99_RS00020	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DRB99_RS00025	ENOG4105CHH	sulfate transporter
DRB99_RS00035	ENOG4105BZU	Histidine kinase
DRB99_RS00040	ENOG4108YZA	Nitrogen regulatory protein pii
DRB99_RS00055	ENOG4105E14	MotA TolQ exbB proton channel
DRB99_RS00060	ENOG4105ER2	Ompa motb domain protein
DRB99_RS00070	ENOG4105C1J	atp-dependent rna helicase
DRB99_RS00075	ENOG4105E9Q	Acyl-transferase
DRB99_RS00080	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DRB99_RS00085	ENOG4105C9K	Endothelin-converting enzyme 1
DRB99_RS00100	ENOG4105VTR	Integrase
DRB99_RS00230	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
DRB99_RS00240	ENOG4105EP8	Glycosyl Hydrolase Family 88
DRB99_RS00245	ENOG4108UZY	PTS System
DRB99_RS00250	ENOG4105ETZ	PTS System
DRB99_RS00255	ENOG4105F3R	pts system mannose fructose sorbose family iid
DRB99_RS00290	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
DRB99_RS00295	ENOG4108YZT	Adenosylcobinamide kinase
DRB99_RS00305	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DRB99_RS00310	ENOG41067QW	Transcriptional regulator
DRB99_RS00355	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
DRB99_RS00370	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DRB99_RS00380	ENOG4108JU6	CBS domain protein
DRB99_RS00385	ENOG4108Z6B	deaminase
DRB99_RS00395	ENOG4105X5K	response regulator receiver protein
DRB99_RS00405	ENOG4105FTQ	Dna gyrase
DRB99_RS00420	ENOG4105EMN	RNA polymerase sigma factor
DRB99_RS00430	ENOG4105D5G	Transposase
DRB99_RS00465	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DRB99_RS00470	ENOG4108JB8	alcohol dehydrogenase
DRB99_RS00480	ENOG4105HDK	L-asparaginase
DRB99_RS00485	ENOG4107R0W	ABC transporter
DRB99_RS00490	ENOG4105E5Q	amino acid AbC transporter
DRB99_RS00495	ENOG4105CDA	abc transporter atp-binding protein
DRB99_RS00500	ENOG4107R0W	ABC transporter
DRB99_RS00510	ENOG4105ERH	Fumarylacetoacetate hydrolase
DRB99_RS00515	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
DRB99_RS00520	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
DRB99_RS00530	ENOG4105C6E	dna polymerase iii
DRB99_RS00565	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DRB99_RS00570	ENOG4108JQ1	Dehydrogenase
DRB99_RS00590	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS00595	ENOG4105C3U	ABC transporter
DRB99_RS00600	ENOG4108JQ7	(ABC) transporter
DRB99_RS00610	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
DRB99_RS00615	ENOG4105CUZ	uba thif-type nad fad binding protein
DRB99_RS00620	ENOG4105D9U	N-acetyltransferase
DRB99_RS00625	ENOG4105CID	antiterminator
DRB99_RS00635	ENOG4105C5Y	PTS System
DRB99_RS00660	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DRB99_RS00675	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DRB99_RS00720	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
DRB99_RS00775	ENOG4105CFC	Transporter
DRB99_RS00795	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DRB99_RS00810	ENOG4105VZ8	Transcriptional regulator
DRB99_RS00830	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DRB99_RS00835	ENOG4105D29	Helix-turn-helix type 11 domain protein
DRB99_RS00865	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DRB99_RS00870	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
DRB99_RS00875	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
DRB99_RS00885	ENOG41068JE	domain protein
DRB99_RS00890	ENOG41060K3	Methyltransferase
DRB99_RS00895	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DRB99_RS00900	ENOG4105KRN	Transcriptional regulator, abrb family
DRB99_RS00910	ENOG4105DVT	helicase
DRB99_RS00920	ENOG4105J5G	Transferase hexapeptide repeat containing protein
DRB99_RS00925	ENOG4107QQG	Dehydrogenase
DRB99_RS00935	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
DRB99_RS00940	ENOG4107U9T	Pfam:Ribonuclease_BN
DRB99_RS00945	ENOG4108UUM	single-stranded DNA-binding protein
DRB99_RS00955	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DRB99_RS00960	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DRB99_RS00975	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
DRB99_RS00980	ENOG4108HHA	Transketolase
DRB99_RS00995	ENOG4105CAK	Cell division ATP-binding protein ftsE
DRB99_RS01000	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
DRB99_RS01015	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DRB99_RS01035	ENOG4105CJN	penicillin-binding protein
DRB99_RS01040	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DRB99_RS01045	ENOG4105D4A	Cell wall formation (By similarity)
DRB99_RS01050	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DRB99_RS01055	ENOG4105CHW	UPF0052 protein
DRB99_RS01060	ENOG4105CIE	May be required for sporulation (By similarity)
DRB99_RS01080	ENOG4105C0B	DNA polymerase III (alpha subunit)
DRB99_RS01110	ENOG4105CA9	Pyruvate kinase
DRB99_RS01135	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
DRB99_RS01165	ENOG4105CZN	Potassium uptake protein
DRB99_RS01170	ENOG4107ZYR	domain protein
DRB99_RS01175	ENOG4105C08	Histidine kinase
DRB99_RS01180	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
DRB99_RS01190	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
DRB99_RS01195	ENOG4108JJ9	ABC, transporter
DRB99_RS01200	ENOG4105BZ1	(ABC) transporter
DRB99_RS01210	ENOG4105WD1	Membrane
DRB99_RS01225	ENOG4108Z5V	transcriptional regulator, merr family
DRB99_RS01230	ENOG4108UQV	Membrane
DRB99_RS01260	ENOG4105DY9	regulatoR
DRB99_RS01265	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS01275	ENOG4105C59	p-type ATPase
DRB99_RS01295	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS01315	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DRB99_RS01330	ENOG4105C3F	Signal peptidase i
DRB99_RS01340	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DRB99_RS01345	ENOG4105EEM	helicase
DRB99_RS01350	ENOG4108HW3	(ABC) transporter
DRB99_RS01355	ENOG4105E5Q	amino acid AbC transporter
DRB99_RS01360	ENOG4105CDA	abc transporter atp-binding protein
DRB99_RS01365	ENOG4105C9K	Endothelin-converting enzyme 1
DRB99_RS01375	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DRB99_RS01380	ENOG4105KFW	domain protein
DRB99_RS01385	ENOG4105EEI	dihydropteroate synthase
DRB99_RS01390	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DRB99_RS01400	ENOG4105DFM	M18 family aminopeptidase
DRB99_RS01415	ENOG4105E2V	Glycosyltransferase 36
DRB99_RS01420	ENOG4105E71	FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
DRB99_RS01425	ENOG4105BZU	Histidine kinase
DRB99_RS01430	ENOG4105BZU	Histidine kinase
DRB99_RS01515	ENOG4108PQP	glycosyl transferase group 1
DRB99_RS01520	ENOG4105K64	Glycosyl transferase, family 2
DRB99_RS01545	ENOG4105K64	Glycosyl transferase, family 2
DRB99_RS01580	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DRB99_RS01635	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DRB99_RS01640	ENOG4105HTX	biosynthesis protein
DRB99_RS01645	ENOG4107YJ4	chain length determinant protein
DRB99_RS01655	ENOG4105D3Q	Sugar transferase
DRB99_RS01660	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DRB99_RS01685	ENOG4108KMV	Glycosyl transferase (Group 1
DRB99_RS01690	ENOG4108KMV	Glycosyl transferase (Group 1
DRB99_RS01695	ENOG4105K64	Glycosyl transferase, family 2
DRB99_RS01705	ENOG4105D5D	udp-galactopyranose mutase
DRB99_RS01710	ENOG4105ER6	polysaccharide biosynthesis protein
DRB99_RS01715	ENOG4105CMR	udp-glucose 4-epimerase
DRB99_RS01720	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS01730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DRB99_RS01800	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
DRB99_RS01805	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DRB99_RS01810	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DRB99_RS01830	ENOG4108KN0	Choline kinase
DRB99_RS01865	ENOG4107T9C	Alpha amylase catalytic region
DRB99_RS01885	ENOG4107RJ1	sodium solute
DRB99_RS01890	ENOG4107SCR	N-acetylneuraminate lyase
DRB99_RS01895	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
DRB99_RS01900	ENOG4106MCE	EamA-like transporter family
DRB99_RS01905	ENOG4105F8D	glycoside hydrolase family 4
DRB99_RS01910	ENOG4105CS2	ec 3.2.1.21
DRB99_RS01915	ENOG410667J	hydrolase
DRB99_RS01920	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS01930	ENOG4105CS2	ec 3.2.1.21
DRB99_RS01945	ENOG4108YZA	Nitrogen regulatory protein pii
DRB99_RS01955	ENOG4107414	GntR family transcriptional regulator
DRB99_RS01965	ENOG4105E90	ABC transporter
DRB99_RS01980	ENOG410641M	
DRB99_RS01985	ENOG4105CS2	ec 3.2.1.21
DRB99_RS02000	ENOG4105DRS	transport system, permease
DRB99_RS02015	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS02025	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS02040	ENOG4105C2X	Arabinose 5-phosphate isomerase
DRB99_RS02045	ENOG4105CK1	PTS System
DRB99_RS02050	ENOG4105VCP	PTS System
DRB99_RS02060	ENOG4105CS2	ec 3.2.1.21
DRB99_RS02070	ENOG4105F8D	glycoside hydrolase family 4
DRB99_RS02085	ENOG4106KNT	transcriptional regulator
DRB99_RS02090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DRB99_RS02095	ENOG4105VCP	PTS System
DRB99_RS02110	ENOG4105CK1	PTS System
DRB99_RS02120	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
DRB99_RS02125	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
DRB99_RS02130	ENOG4105E98	transcriptional regulator DeoR family
DRB99_RS02145	ENOG4107STF	Involved in phosphonate degradation (By similarity)
DRB99_RS02150	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
DRB99_RS02155	ENOG4108JPW	Aminotransferase
DRB99_RS02170	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DRB99_RS02175	ENOG4108P49	AntiSigma factor
DRB99_RS02180	ENOG4105JVQ	RNA Polymerase
DRB99_RS02185	ENOG410620I	Diguanylate cyclase
DRB99_RS02190	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
DRB99_RS02205	ENOG4105KPE	licD family
DRB99_RS02225	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
DRB99_RS02230	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS02240	ENOG4105D3Q	Sugar transferase
DRB99_RS02255	ENOG4105KY8	Rubrerythrin
DRB99_RS02260	ENOG4105CJ1	ABC, transporter
DRB99_RS02265	ENOG4108TU7	Inherit from COG: (ABC) transporter
DRB99_RS02270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DRB99_RS02280	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS02285	ENOG4105BZU	Histidine kinase
DRB99_RS02290	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DRB99_RS02295	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DRB99_RS02300	ENOG4105BZU	Histidine kinase
DRB99_RS02310	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DRB99_RS02330	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS02375	ENOG4107S9R	deoxycytidine triphosphate deaminase
DRB99_RS02380	ENOG4105CJ1	ABC, transporter
DRB99_RS02395	ENOG4105C8T	Leucyl-tRNA synthetase
DRB99_RS02415	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
DRB99_RS02420	ENOG4105D49	3-dehydroquinate synthase
DRB99_RS02425	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DRB99_RS02430	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DRB99_RS02435	ENOG4105CQC	Prephenate dehydratase
DRB99_RS02440	ENOG4105E2X	shikimate dehydrogenase
DRB99_RS02450	ENOG4105C5Q	Transcriptional regulator
DRB99_RS02460	ENOG4105FTV	AraC Family Transcriptional Regulator
DRB99_RS02465	ENOG4105EMV	Major Facilitator
DRB99_RS02470	ENOG4105E2X	shikimate dehydrogenase
DRB99_RS02480	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DRB99_RS02485	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
DRB99_RS02495	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
DRB99_RS02505	ENOG4105QEK	Transcriptional regulator
DRB99_RS02520	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS02530	ENOG4108JQ7	(ABC) transporter
DRB99_RS02535	ENOG4107SCR	N-acetylneuraminate lyase
DRB99_RS02540	ENOG4107EFR	Flavocytochrome c
DRB99_RS02545	ENOG4105I82	acetyl xylan esterase
DRB99_RS02555	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
DRB99_RS02565	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
DRB99_RS02585	ENOG4105C2F	Histidine kinase
DRB99_RS02590	ENOG4107VQW	regulatoR
DRB99_RS02620	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
DRB99_RS02625	ENOG4105CKB	glycosidase
DRB99_RS02630	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS02655	ENOG4105CS2	ec 3.2.1.21
DRB99_RS02660	ENOG4105DG6	mannose-6-phosphate isomerase
DRB99_RS02665	ENOG4108TZY	GntR Family Transcriptional Regulator
DRB99_RS02670	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
DRB99_RS02680	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
DRB99_RS02695	ENOG4108NV9	Glycosyl Transferase
DRB99_RS02710	ENOG4105VKD	bioY protein
DRB99_RS02715	ENOG4105DBV	ornithine carbamoyltransferase
DRB99_RS02720	ENOG4105C8Y	Acetylornithine aminotransferase
DRB99_RS02725	ENOG4105CAS	nag kinase
DRB99_RS02730	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DRB99_RS02735	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DRB99_RS02740	ENOG4105CH7	arginosuccinase
DRB99_RS02745	ENOG4105CDH	Citrulline--aspartate ligase
DRB99_RS02755	ENOG4108QG2	Membrane
DRB99_RS02760	ENOG4105C22	threonyL-tRNA synthetase
DRB99_RS02780	ENOG4105EJQ	L-serine dehydratase
DRB99_RS02790	ENOG4105CZN	Potassium uptake protein
DRB99_RS02795	ENOG4107ZYR	domain protein
DRB99_RS02810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DRB99_RS02815	ENOG4108Z40	Transcriptional regulator
DRB99_RS02825	ENOG4105C5H	ABC transporter
DRB99_RS02840	ENOG4108NGU	Transcriptional regulator
DRB99_RS02850	ENOG4105UEI	Transcriptional Regulator AraC Family
DRB99_RS02875	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
DRB99_RS02880	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DRB99_RS02890	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DRB99_RS02895	ENOG4105DB7	PHP domain protein
DRB99_RS02910	ENOG410667J	hydrolase
DRB99_RS02920	ENOG4108S8M	degv family
DRB99_RS02945	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS02950	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
DRB99_RS02955	ENOG4105CMR	udp-glucose 4-epimerase
DRB99_RS02960	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DRB99_RS02965	ENOG4107RK0	Sucrose phosphorylase
DRB99_RS02975	ENOG4108R6W	Transcriptional regulator, ARAC family
DRB99_RS02995	ENOG4105DRS	transport system, permease
DRB99_RS03000	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS03020	ENOG4105DKQ	ROK family
DRB99_RS03030	ENOG4105G6Z	alkaline phosphatase
DRB99_RS03045	ENOG4105CXN	decarboxylase
DRB99_RS03065	ENOG4105CYW	agmatinase
DRB99_RS03080	ENOG4105CQ4	Transcriptional regulator
DRB99_RS03100	ENOG4105C4C	beta-galactosidase
DRB99_RS03105	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS03110	ENOG4105C2F	Histidine kinase
DRB99_RS03115	ENOG4105EQD	regulatoR
DRB99_RS03120	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
DRB99_RS03130	ENOG4108R6W	Transcriptional regulator, ARAC family
DRB99_RS03170	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DRB99_RS03180	ENOG4105DTI	Phosphonopyruvate decarboxylase
DRB99_RS03185	ENOG4107STF	Involved in phosphonate degradation (By similarity)
DRB99_RS03200	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
DRB99_RS03210	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
DRB99_RS03215	ENOG4105BZ8	glutamate synthase
DRB99_RS03225	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS03245	ENOG4105CID	antiterminator
DRB99_RS03250	ENOG4105C5Y	PTS System
DRB99_RS03255	ENOG4105DB7	PHP domain protein
DRB99_RS03275	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
DRB99_RS03280	ENOG4105BZ8	glutamate synthase
DRB99_RS03285	ENOG4107RDB	Major Facilitator
DRB99_RS03295	ENOG4106N3A	copper homeostasis protein cutc
DRB99_RS03300	ENOG4108SWU	Histidine kinase
DRB99_RS03305	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DRB99_RS03310	ENOG4108RSN	SNARE associated Golgi
DRB99_RS03315	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
DRB99_RS03325	ENOG4108WCX	response regulator
DRB99_RS03335	ENOG4105DA5	(ABC) transporter
DRB99_RS03350	ENOG4105VMP	Transcriptional regulator
DRB99_RS03375	ENOG4108R66	Conserved Protein
DRB99_RS03400	ENOG4105C5Q	Transcriptional regulator
DRB99_RS03410	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DRB99_RS03420	ENOG4105BZG	amino acid carrier protein
DRB99_RS03425	ENOG41084AG	Acylphosphatase
DRB99_RS03430	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
DRB99_RS03440	ENOG4105D38	putrescine abc transporter
DRB99_RS03445	ENOG4105F38	ABC transporter, permease
DRB99_RS03470	ENOG4105BZ4	penicillin-binding protein
DRB99_RS03485	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DRB99_RS03500	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
DRB99_RS03515	ENOG4107QHF	type ii secretion system protein e
DRB99_RS03520	ENOG4105D7Q	type ii secretion system
DRB99_RS03570	ENOG4105CFH	Aspartokinase
DRB99_RS03580	ENOG4108YZA	Nitrogen regulatory protein pii
DRB99_RS03600	ENOG4105BZ8	glutamate synthase
DRB99_RS03615	ENOG4105DUM	transcriptional regulator, lysR family
DRB99_RS03630	ENOG4108IV0	ABC, transporter
DRB99_RS03635	ENOG4105C0Z	ABC transporter
DRB99_RS03640	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DRB99_RS03645	ENOG4105C32	Amino acid ABC transporter (Permease)
DRB99_RS03670	ENOG4105C2M	dna polymerase I
DRB99_RS03680	ENOG4105E4C	Lytic transglycosylase catalytic
DRB99_RS03710	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS03715	ENOG4105DDQ	anthranilate synthase
DRB99_RS03720	ENOG4105CRQ	synthase (Component I)
DRB99_RS03725	ENOG4107Z5F	Aminotransferase class IV
DRB99_RS03750	ENOG4105BZU	Histidine kinase
DRB99_RS03755	ENOG4105KAV	tspo and mbr like protein
DRB99_RS03760	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DRB99_RS03765	ENOG4105D2X	ABC transporter substrate-binding protein
DRB99_RS03775	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
DRB99_RS03795	ENOG4105DZ1	carboxypeptidase
DRB99_RS03805	ENOG4105F1K	Glutamine amidotransferase
DRB99_RS03810	ENOG4105DMS	mur ligase
DRB99_RS03820	ENOG4105CFP	Peptidase U32
DRB99_RS03825	ENOG4105C98	muts2 protein
DRB99_RS03830	ENOG4105EWC	Purine nucleoside phosphorylase
DRB99_RS03835	ENOG4105D5Q	Arginine ornithine antiporter
DRB99_RS03850	ENOG4105EYH	Exonuclease
DRB99_RS03855	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DRB99_RS03860	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DRB99_RS03880	ENOG4105CJR	Integral membrane protein (MviN
DRB99_RS03890	ENOG4105CPK	Glycosyl transferase (Group 1
DRB99_RS03915	ENOG4105C3G	gtp-binding protein
DRB99_RS03945	ENOG4105CXT	aspartate transcarbamylase
DRB99_RS03960	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
DRB99_RS03975	ENOG4107T14	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DRB99_RS03980	ENOG4105C6N	Formate acetyltransferase
DRB99_RS04000	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DRB99_RS04015	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DRB99_RS04020	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
DRB99_RS04030	ENOG4108Z4T	Peptidase M50
DRB99_RS04035	ENOG4105C75	arginyL-tRNA synthetase
DRB99_RS04040	ENOG4108REF	Sporulation integral membrane protein ytvi
DRB99_RS04060	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
DRB99_RS04075	ENOG4105WG9	Conserved Protein
DRB99_RS04080	ENOG4108VVK	transcriptional Regulator, AsnC
DRB99_RS04115	ENOG4105CAQ	asparagine synthetase
DRB99_RS04130	ENOG4105XVJ	Protein of unknown function (DUF327)
DRB99_RS04145	ENOG4105D7T	ABC transporter
DRB99_RS04155	ENOG4105BZ1	(ABC) transporter
DRB99_RS04160	ENOG4105K63	Thioredoxin
DRB99_RS04165	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DRB99_RS04170	ENOG4108DWA	Nad synthetase
DRB99_RS04185	ENOG4105CK2	sodium dicarboxylate symporter
DRB99_RS04195	ENOG4108HW3	(ABC) transporter
DRB99_RS04200	ENOG4105DRP	amino acid AbC transporter
DRB99_RS04205	ENOG4105CDA	abc transporter atp-binding protein
DRB99_RS04215	ENOG4107R4J	Chloride channel
DRB99_RS04220	ENOG4105JVQ	RNA Polymerase
DRB99_RS04230	ENOG4108IJ0	Aspartate ammonia-lyase
DRB99_RS04240	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DRB99_RS04255	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DRB99_RS04260	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
DRB99_RS04265	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DRB99_RS04270	ENOG4105C12	Phosphoribosylglycinamide synthetase
DRB99_RS04280	ENOG4105BZU	Histidine kinase
DRB99_RS04285	ENOG4108115	UPF0145 protein
DRB99_RS04310	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DRB99_RS04320	ENOG4105EA8	2-Nitropropane dioxygenase
DRB99_RS04325	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DRB99_RS04330	ENOG4105CHR	reductase
DRB99_RS04335	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DRB99_RS04350	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DRB99_RS04355	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
DRB99_RS04360	ENOG4108FRU	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
DRB99_RS04375	ENOG4105C7J	ABC transporter, permease
DRB99_RS04385	ENOG4105D1H	recombination factor protein RarA
DRB99_RS04400	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
DRB99_RS04405	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DRB99_RS04415	ENOG4105C02	permease
DRB99_RS04420	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DRB99_RS04425	ENOG4105VBH	UPF0297 protein
DRB99_RS04430	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DRB99_RS04435	ENOG4105VGP	UPF0473 protein
DRB99_RS04440	ENOG4105I3K	Ferric uptake regulator, Fur family
DRB99_RS04445	ENOG4105CN5	Metallo-Beta-Lactamase
DRB99_RS04450	ENOG4105CI3	gtp-binding protein typa
DRB99_RS04455	ENOG4105HHA	aminodeoxychorismate lyase
DRB99_RS04465	ENOG4105CFP	Peptidase U32
DRB99_RS04475	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS04480	ENOG4105CZX	twitching motility protein
DRB99_RS04490	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DRB99_RS04495	ENOG4105FFI	sigma-e processing peptidase spoiiga
DRB99_RS04500	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS04505	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS04510	ENOG4105WR5	sporulation protein, YlmC YmxH family
DRB99_RS04515	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DRB99_RS04520	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DRB99_RS04525	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS04530	ENOG4105BZU	Histidine kinase
DRB99_RS04535	ENOG4105CVA	phosphate
DRB99_RS04540	ENOG4105C8U	phosphate abc transporter
DRB99_RS04545	ENOG4105E2Z	phosphate ABC transporter (Permease
DRB99_RS04550	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DRB99_RS04570	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DRB99_RS04575	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DRB99_RS04590	ENOG4105HDK	L-asparaginase
DRB99_RS04595	ENOG4105C7N	Xanthine uracil vitamin C permease
DRB99_RS04600	ENOG4105DSJ	YicC domain protein
DRB99_RS04615	ENOG410880J	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DRB99_RS04620	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DRB99_RS04625	ENOG4105C25	Primosomal protein n'
DRB99_RS04635	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DRB99_RS04640	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DRB99_RS04645	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DRB99_RS04650	ENOG4108ZF3	Phosphatase
DRB99_RS04660	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DRB99_RS04665	ENOG4105DJV	ribulose-phosphate 3-epimerase
DRB99_RS04675	ENOG4105VB9	50S ribosomal protein l28
DRB99_RS04685	ENOG4105DP4	dak2 domain fusion protein ylov
DRB99_RS04690	ENOG4105CQ4	Transcriptional regulator
DRB99_RS04695	ENOG4105CB5	ATP-dependent DNA helicase recG
DRB99_RS04700	ENOG4106H78	methyltransferase
DRB99_RS04705	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DRB99_RS04720	ENOG4105CDE	UPF0348 protein
DRB99_RS04725	ENOG4108IJ2	phosphate acetyltransferase
DRB99_RS04730	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
DRB99_RS04745	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
DRB99_RS04755	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DRB99_RS04770	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DRB99_RS04775	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
DRB99_RS04785	ENOG4105K5M	30s ribosomal protein S16
DRB99_RS04795	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DRB99_RS04800	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DRB99_RS04805	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DRB99_RS04810	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
DRB99_RS04815	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DRB99_RS04825	ENOG4105C0P	Mg chelatase subunit ChlI
DRB99_RS04830	ENOG4105C79	DNA protecting protein DprA
DRB99_RS04835	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DRB99_RS04840	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
DRB99_RS04845	ENOG4105CE9	30S ribosomal protein S2
DRB99_RS04855	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DRB99_RS04865	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DRB99_RS04870	ENOG4105KNE	Phosphatidate cytidylyltransferase
DRB99_RS04905	ENOG4105CHV	Transcription elongation factor NusA
DRB99_RS04910	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
DRB99_RS04920	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DRB99_RS04925	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DRB99_RS04940	ENOG4105DTN	riboflavin biosynthesis protein ribF
DRB99_RS04945	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DRB99_RS04950	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DRB99_RS04955	ENOG4105C1V	Peptidase, M16
DRB99_RS04970	ENOG4108W8B	Beta-lactamase domain protein
DRB99_RS04985	ENOG4108UW5	maltose o-acetyltransferase
DRB99_RS04990	ENOG4105CID	antiterminator
DRB99_RS04995	ENOG4105C5Y	PTS System
DRB99_RS05005	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
DRB99_RS05015	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
DRB99_RS05020	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DRB99_RS05025	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DRB99_RS05030	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
DRB99_RS05035	ENOG4105MCT	stage V sporulation protein S
DRB99_RS05065	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DRB99_RS05070	ENOG4108R6K	riboflavin synthase, subunit alpha
DRB99_RS05075	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
DRB99_RS05080	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DRB99_RS05090	ENOG4105KY8	Rubrerythrin
DRB99_RS05120	ENOG4105HEE	Binding Domain protein
DRB99_RS05135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS05140	ENOG4105F3H	Histidine kinase
DRB99_RS05145	ENOG4108VW9	Membrane
DRB99_RS05155	ENOG4108YZA	Nitrogen regulatory protein pii
DRB99_RS05160	ENOG4107QKW	extracellular solute-binding protein family 1
DRB99_RS05165	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DRB99_RS05170	ENOG4105F38	ABC transporter, permease
DRB99_RS05175	ENOG4105D38	putrescine abc transporter
DRB99_RS05195	ENOG41061ZR	Transcriptional regulator
DRB99_RS05205	ENOG4107S8T	NAD-dependent 4-hydroxybutyrate dehydrogenase
DRB99_RS05230	ENOG4107XGZ	Hydrolase
DRB99_RS05250	ENOG4105UQX	Mate efflux family protein
DRB99_RS05260	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
DRB99_RS05270	ENOG4107RWR	Sodium hydrogen exchanger
DRB99_RS05315	ENOG4105CHR	reductase
DRB99_RS05320	ENOG4105BZU	Histidine kinase
DRB99_RS05325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS05330	ENOG4108J6I	peptidase, M16
DRB99_RS05355	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
DRB99_RS05365	ENOG4105UQX	Mate efflux family protein
DRB99_RS05385	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DRB99_RS05400	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
DRB99_RS05405	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
DRB99_RS05410	ENOG4105W7A	Protein of unknown function (DUF503)
DRB99_RS05420	ENOG4105DU1	integral membrane protein, terc
DRB99_RS05460	ENOG4108IUM	Glycogen debranching enzyme
DRB99_RS05465	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
DRB99_RS05470	ENOG4105CHM	Aminotransferase
DRB99_RS05480	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS05485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS05495	ENOG4108JQ7	(ABC) transporter
DRB99_RS05500	ENOG4108J59	Extracellular solute-binding protein, family 5
DRB99_RS05505	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS05510	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
DRB99_RS05520	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS05525	ENOG4107RRN	ABC transporter substrate-binding protein
DRB99_RS05530	ENOG4105C3U	ABC transporter
DRB99_RS05535	ENOG4108JQ7	(ABC) transporter
DRB99_RS05545	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DRB99_RS05555	ENOG4105DXX	methyltransferase
DRB99_RS05560	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
DRB99_RS05565	ENOG4105FKZ	Methyl-accepting chemotaxis
DRB99_RS05575	ENOG4107TUM	Amidinotransferase
DRB99_RS05580	ENOG4108JCI	Transcriptional regulator
DRB99_RS05600	ENOG4108JPW	Aminotransferase
DRB99_RS05610	ENOG4105C8Y	Acetylornithine aminotransferase
DRB99_RS05615	ENOG4107YTP	response regulator receiver protein
DRB99_RS05650	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DRB99_RS05660	ENOG4107ZYR	domain protein
DRB99_RS05665	ENOG4108RWN	rrna methyltransferase
DRB99_RS05670	ENOG4105CBX	hi0933 family
DRB99_RS05690	ENOG4107BJW	polysaccharide deacetylase
DRB99_RS05705	ENOG4105BZ1	(ABC) transporter
DRB99_RS05715	ENOG4105VUC	UPF0237 protein
DRB99_RS05720	ENOG4105CAG	UPF0210 protein
DRB99_RS05750	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DRB99_RS05755	ENOG4105CGK	Exodeoxyribonuclease III
DRB99_RS05775	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DRB99_RS05800	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
DRB99_RS05820	ENOG4105EQD	regulatoR
DRB99_RS05825	ENOG4105C2F	Histidine kinase
DRB99_RS05835	ENOG4105D56	permease protein
DRB99_RS05840	ENOG4105EG2	ABC transporter, permease
DRB99_RS05855	ENOG4108IUM	Glycogen debranching enzyme
DRB99_RS05875	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DRB99_RS05880	ENOG4105EUJ	GTP cyclohydrolase i
DRB99_RS05885	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DRB99_RS05890	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
DRB99_RS05900	ENOG4105K56	Transcriptional regulator
DRB99_RS05905	ENOG4105BZ1	(ABC) transporter
DRB99_RS05910	ENOG4105BZ1	(ABC) transporter
DRB99_RS05935	ENOG4105DZ1	carboxypeptidase
DRB99_RS05945	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
DRB99_RS05950	ENOG4105KBJ	sporulation protein ytfj
DRB99_RS05960	ENOG4105DZ1	carboxypeptidase
DRB99_RS05975	ENOG4107RU2	Histidinol phosphate phosphatase, HisJ family
DRB99_RS05980	ENOG4105DBV	ornithine carbamoyltransferase
DRB99_RS05985	ENOG4108W76	histidinol phosphate phosphatase hisj family
DRB99_RS05990	ENOG4105FDP	GntR family transcriptional regulator
DRB99_RS06010	ENOG4105FT8	Phosphonate metabolism
DRB99_RS06015	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
DRB99_RS06020	ENOG4105FD8	phosphonate metabolism protein PhnM
DRB99_RS06025	ENOG4105HRV	phosphonate c-p lyase system protein phnl
DRB99_RS06030	ENOG4105DB7	PHP domain protein
DRB99_RS06040	ENOG4105D5T	phosphonate abc transporter
DRB99_RS06050	ENOG4105S7S	phosphonate abc transporter
DRB99_RS06060	ENOG4107X8C	Efflux transporter RND family MFP subunit
DRB99_RS06065	ENOG4105CW7	secretion protein, HlyD family
DRB99_RS06070	ENOG4105BZ1	(ABC) transporter
DRB99_RS06100	ENOG4105C98	muts2 protein
DRB99_RS06155	ENOG4105EYH	Exonuclease
DRB99_RS06210	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DRB99_RS06350	ENOG4105K4H	Nlp p60 protein
DRB99_RS06405	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
DRB99_RS06435	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
DRB99_RS06445	ENOG4105QUH	Domain of unknown function (DUF2088)
DRB99_RS06450	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
DRB99_RS06455	ENOG4108I5D	sulfate abc transporter
DRB99_RS06460	ENOG4105ECW	sulfate abc transporter
DRB99_RS06465	ENOG4108IJ6	ABC transporter
DRB99_RS06475	ENOG4105WCA	Ferredoxin
DRB99_RS06480	ENOG4105C11	sulfate adenylyltransferase), subunit 2
DRB99_RS06485	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
DRB99_RS06510	ENOG4108Z86	Glutamine amidotransferase
DRB99_RS06520	ENOG4108RCM	Nitroreductase
DRB99_RS06530	ENOG4105BZJ	Electron transfer flavoprotein
DRB99_RS06535	ENOG4105C10	Electron transfer flavoprotein
DRB99_RS06545	ENOG4105CQB	FAD linked oxidase domain protein
DRB99_RS06550	ENOG4105C1G	acyl-Coa dehydrogenase
DRB99_RS06600	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
DRB99_RS06605	ENOG4105DZC	cytosine deaminase
DRB99_RS06640	ENOG4105C9B	Cysteine desulfurase
DRB99_RS06695	ENOG4105CDU	Replicative dna helicase
DRB99_RS06710	ENOG4107R3N	Filamentation induced by cAMP protein fic
DRB99_RS06715	ENOG4105C4Y	ABC transporter
DRB99_RS06720	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DRB99_RS06725	ENOG4107RCV	ABC transporter, permease
DRB99_RS06735	ENOG4107VQW	regulatoR
DRB99_RS06750	ENOG4105M6F	mutator MutT protein
DRB99_RS06775	ENOG4105CH2	amidohydrolase
DRB99_RS06780	ENOG4105CGH	5'-nucleotidase
DRB99_RS06830	ENOG4105CVJ	phosphoglycerate mutase
DRB99_RS06835	ENOG4105E0M	Sulfatase
DRB99_RS06855	ENOG4108X4Q	Hydrolase
DRB99_RS06865	ENOG4105BZU	Histidine kinase
DRB99_RS06870	ENOG4105CPC	Aldo Keto reductase
DRB99_RS06875	ENOG4107SC7	Inner membrane transporter yjeM
DRB99_RS06885	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
DRB99_RS06890	ENOG4105DVE	abc transporter atp-binding protein
DRB99_RS06935	ENOG4105D64	Mechanosensitive ion channel
DRB99_RS06955	ENOG4105E5D	amino acid
DRB99_RS06980	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
DRB99_RS06990	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DRB99_RS06995	ENOG4105DIW	FeS assembly protein SUFB
DRB99_RS07030	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DRB99_RS07045	ENOG4105DHS	permease protein
DRB99_RS07050	ENOG4105CM4	permease protein
DRB99_RS07055	ENOG4108IPW	abc transporter atp-binding protein
DRB99_RS07065	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DRB99_RS07100	ENOG4107SGM	protein serine threonine phosphatase
DRB99_RS07105	ENOG4105DHI	Methyltransferase
DRB99_RS07110	ENOG4105EAM	Na Pi-cotransporter
DRB99_RS07115	ENOG4108ZMI	UPF0477 protein
DRB99_RS07140	ENOG4105C1A	potassium transporter peripheral membrane
DRB99_RS07145	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
DRB99_RS07150	ENOG4105FE9	pseudouridine synthase
DRB99_RS07160	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DRB99_RS07170	ENOG4107RVG	penicillin-binding protein
DRB99_RS07200	ENOG4108VJ1	Transcriptional regulator (CarD family
DRB99_RS07205	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
DRB99_RS07220	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DRB99_RS07225	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DRB99_RS07235	ENOG4105DER	m42 family
DRB99_RS07265	ENOG4105WXW	Antirepressor
DRB99_RS07280	ENOG4105KRN	Transcriptional regulator, abrb family
DRB99_RS07320	ENOG4106HDD	
DRB99_RS07370	ENOG4105WEF	catalase
DRB99_RS07630	ENOG4105CKI	cobalamin synthesis protein
DRB99_RS07640	ENOG4108PJD	permease
DRB99_RS07655	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DRB99_RS07705	ENOG4105VEV	-acetyltransferase
DRB99_RS07730	ENOG4108Z6Z	Transcriptional regulator
DRB99_RS07745	ENOG4108HW3	(ABC) transporter
DRB99_RS07750	ENOG4105E5Q	amino acid AbC transporter
DRB99_RS07765	ENOG4105ETU	transcriptional activator (TenA
DRB99_RS07775	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS07810	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
DRB99_RS07815	ENOG4107QQ0	gntp family
DRB99_RS07820	ENOG4105BZW	Glycerate kinase
DRB99_RS07830	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
DRB99_RS07835	ENOG4105CBX	hi0933 family
DRB99_RS07845	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DRB99_RS07860	ENOG4105CKI	cobalamin synthesis protein
DRB99_RS07885	ENOG4105D5G	Transposase
DRB99_RS07890	ENOG4108Z66	YbaK ebsC protein
DRB99_RS07895	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRB99_RS07915	ENOG4105CXI	aluminum resistance protein
DRB99_RS07925	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
DRB99_RS07930	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DRB99_RS07935	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
DRB99_RS07955	ENOG4105C7N	Xanthine uracil vitamin C permease
DRB99_RS07970	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DRB99_RS07975	ENOG4105KWG	Pfam:DUF1696
DRB99_RS07985	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DRB99_RS08000	ENOG4107RBB	ABC transporter, permease
DRB99_RS08005	ENOG4105C19	ABC transporter
DRB99_RS08020	ENOG4105BZU	Histidine kinase
DRB99_RS08035	ENOG4108IFG	nitrite reductase, (NAD(P)H)
DRB99_RS08045	ENOG41069ER	domain protein
DRB99_RS08050	ENOG4108UH6	UPF0754 membrane protein
DRB99_RS08065	ENOG4105EAM	Na Pi-cotransporter
DRB99_RS08070	ENOG4105KT7	mgtC SapB transporter
DRB99_RS08085	ENOG4105C5H	ABC transporter
DRB99_RS08110	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DRB99_RS08115	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
DRB99_RS08120	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DRB99_RS08125	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DRB99_RS08130	ENOG4105DDQ	anthranilate synthase
DRB99_RS08145	ENOG4105C1J	atp-dependent rna helicase
DRB99_RS08215	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
DRB99_RS08250	ENOG4105E98	transcriptional regulator DeoR family
DRB99_RS08255	ENOG4108X4Q	Hydrolase
DRB99_RS08260	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DRB99_RS08275	ENOG4105D6J	arsenicaL-resistance protein
DRB99_RS08295	ENOG4105YVS	arsR family transcriptional regulator
DRB99_RS08305	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DRB99_RS08315	ENOG4107YTP	response regulator receiver protein
DRB99_RS08325	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DRB99_RS08335	ENOG4108HCJ	Hydrolase
DRB99_RS08360	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
DRB99_RS08365	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
DRB99_RS08375	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
DRB99_RS08390	ENOG4108YZ4	nudix hydrolase
DRB99_RS08395	ENOG410807C	QueT transporter
DRB99_RS08415	ENOG4105C3S	Mate efflux family protein
DRB99_RS08420	ENOG4105KNA	-acetyltransferase
DRB99_RS08435	ENOG4105JAB	phenazine biosynthesis protein, phzf family
DRB99_RS08440	ENOG4105KT7	mgtC SapB transporter
DRB99_RS08460	ENOG4105F6S	Spore photoproduct lyase
DRB99_RS08560	ENOG4105I1F	Resistance protein
DRB99_RS08580	ENOG4105DVT	helicase
DRB99_RS08625	ENOG4105CDU	Replicative dna helicase
DRB99_RS08655	ENOG4105DZR	Type I site-specific deoxyribonuclease
DRB99_RS08740	ENOG4105BZU	Histidine kinase
DRB99_RS08765	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
DRB99_RS08810	ENOG4108V4B	ThiJ pfpI
DRB99_RS08820	ENOG4105KVH	Transcriptional regulator
DRB99_RS08850	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DRB99_RS08895	ENOG41086D8	Transcriptional regulator
DRB99_RS08905	ENOG4108Z0Z	intracellular protease Pfpi family
DRB99_RS08915	ENOG4105C5H	ABC transporter
DRB99_RS08920	ENOG4105VUF	Transcriptional regulator
DRB99_RS08925	ENOG4105EMU	Dehydrogenase
DRB99_RS08930	ENOG4107TXC	Transcriptional regulator
DRB99_RS08980	ENOG4105DA5	(ABC) transporter
DRB99_RS09000	ENOG4107QJQ	Mate efflux family protein
DRB99_RS09005	ENOG4105C4B	ABC transporter, permease
DRB99_RS09010	ENOG41083J0	(ABC) transporter
DRB99_RS09040	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
DRB99_RS09050	ENOG4105C7W	Xanthine dehydrogenase
DRB99_RS09080	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
DRB99_RS09085	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
DRB99_RS09090	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
DRB99_RS09100	ENOG4108JCI	Transcriptional regulator
DRB99_RS09110	ENOG4107RN3	metallophosphoesterase
DRB99_RS09120	ENOG4107QHI	-hydrogenase
DRB99_RS09125	ENOG4107QIZ	NADH dehydrogenase
DRB99_RS09145	ENOG4107YY3	extracellular solute-binding protein family 1
DRB99_RS09150	ENOG4105CG3	alpha amylase, catalytic region
DRB99_RS09155	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS09180	ENOG4105CQB	FAD linked oxidase domain protein
DRB99_RS09185	ENOG4108UMI	ABC transporter, permease
DRB99_RS09190	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DRB99_RS09195	ENOG4105D01	(LipO)protein
DRB99_RS09200	ENOG4105CHM	Aminotransferase
DRB99_RS09205	ENOG4105C28	cystathionine
DRB99_RS09215	ENOG4105UPD	Calcium Proton
DRB99_RS09220	ENOG4106F1P	AAA ATPase, central domain protein
DRB99_RS09225	ENOG4105CVJ	phosphoglycerate mutase
DRB99_RS09265	ENOG4105CHM	Aminotransferase
DRB99_RS09270	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DRB99_RS09280	ENOG4107QSE	Dipeptidase
DRB99_RS09305	ENOG4107R88	Chemotaxis protein (CheV)
DRB99_RS09315	ENOG4105BZU	Histidine kinase
DRB99_RS09330	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DRB99_RS09335	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DRB99_RS09345	ENOG4105D9U	N-acetyltransferase
DRB99_RS09360	ENOG4105CUT	histidyl-tRNA synthetase
DRB99_RS09365	ENOG4107IFA	Lipase (EC 3.1.1.3)
DRB99_RS09395	ENOG4105DM4	PTS System
DRB99_RS09400	ENOG4105DE4	1-phosphofructokinase
DRB99_RS09405	ENOG4105E98	transcriptional regulator DeoR family
DRB99_RS09420	ENOG4105CT4	transporter
DRB99_RS09435	ENOG4105F5H	Glycosyl Hydrolase Family 88
DRB99_RS09445	ENOG4105CHR	reductase
DRB99_RS09450	ENOG4105CTX	dehydratase
DRB99_RS09455	ENOG4107QZW	Altronate oxidoreductase
DRB99_RS09460	ENOG4105D7K	pfkb domain protein
DRB99_RS09465	ENOG4108UHU	Aldolase
DRB99_RS09470	ENOG4105D2H	Uronic isomerase
DRB99_RS09475	ENOG4107KJX	Transcriptional regulator
DRB99_RS09500	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DRB99_RS09505	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DRB99_RS09510	ENOG4105DRP	amino acid AbC transporter
DRB99_RS09515	ENOG4105EAD	ABC transporter
DRB99_RS09520	ENOG4107RP9	extracellular solute-binding protein, family 3
DRB99_RS09535	ENOG4105C1J	atp-dependent rna helicase
DRB99_RS09545	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DRB99_RS09555	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DRB99_RS09565	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DRB99_RS09580	ENOG4105XXY	Thioredoxin
DRB99_RS09585	ENOG410667J	hydrolase
DRB99_RS09590	ENOG410631K	Membrane
DRB99_RS09620	ENOG4105C7K	acetolactate synthase
DRB99_RS09625	ENOG4105M71	acetolactate synthase 1 regulatory subunit
DRB99_RS09630	ENOG410901E	Membrane
DRB99_RS09640	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DRB99_RS09645	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DRB99_RS09650	ENOG41086VR	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DRB99_RS09660	ENOG4105C5S	asparaginyl-tRNA synthetase
DRB99_RS09670	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
DRB99_RS09675	ENOG4107V2S	Transcriptional regulator
DRB99_RS09695	ENOG4107Y70	Heat shock protein
DRB99_RS09715	ENOG4107R4J	Chloride channel
DRB99_RS09730	ENOG4105BZU	Histidine kinase
DRB99_RS09765	ENOG4105WEF	catalase
DRB99_RS09780	ENOG4107QIV	Cytochrome c biogenesis protein
DRB99_RS09785	ENOG4105KVH	Transcriptional regulator
DRB99_RS09795	ENOG4107QN2	dihydrolipoyl dehydrogenase
DRB99_RS09800	ENOG4105K63	Thioredoxin
DRB99_RS09805	ENOG4105C3M	thioredoxin reductase
DRB99_RS09815	ENOG4105EAB	amino acid AbC transporter
DRB99_RS09830	ENOG4105WEF	catalase
DRB99_RS09835	ENOG4108YZ4	nudix hydrolase
DRB99_RS09845	ENOG4108Z29	Flavodoxin
DRB99_RS09855	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DRB99_RS09865	ENOG4105CK7	Sodium proline symporter
DRB99_RS09875	ENOG4105EC8	Methyl-accepting chemotaxis
DRB99_RS09890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRB99_RS09905	ENOG4108IV0	ABC, transporter
DRB99_RS09910	ENOG4105C0Z	ABC transporter
DRB99_RS09915	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DRB99_RS09920	ENOG4105C32	Amino acid ABC transporter (Permease)
DRB99_RS09930	ENOG4105FKZ	Methyl-accepting chemotaxis
DRB99_RS09935	ENOG4105M18	-acetyltransferase
DRB99_RS09980	ENOG4107QQR	Sporulation
DRB99_RS09985	ENOG4105S1Z	Stage IV sporulation protein B
DRB99_RS09990	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DRB99_RS09995	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DRB99_RS10000	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DRB99_RS10005	ENOG4105DX0	Hemolysin A
DRB99_RS10010	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DRB99_RS10015	ENOG4105CTB	Polyprenyl synthetase
DRB99_RS10020	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DRB99_RS10025	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DRB99_RS10035	ENOG4105M7K	Involved in the transcription termination process (By similarity)
DRB99_RS10040	ENOG4108ZSR	alkaline shock protein
DRB99_RS10065	ENOG4105KQ4	Stage iii sporulation protein ad
DRB99_RS10080	ENOG4105CD2	stage iii sporulation protein aa
DRB99_RS10155	ENOG4105QEK	Transcriptional regulator
DRB99_RS10160	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
DRB99_RS10170	ENOG4105C34	Pseudouridine synthase
DRB99_RS10190	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
DRB99_RS10195	ENOG4105DFA	alanine racemase domain protein
DRB99_RS10205	ENOG4105K67	small basic protein
DRB99_RS10220	ENOG4105CNI	cell division protein FtsW
DRB99_RS10225	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DRB99_RS10230	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
DRB99_RS10240	ENOG4105CJN	penicillin-binding protein
DRB99_RS10245	ENOG4105CJN	penicillin-binding protein
DRB99_RS10255	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DRB99_RS10260	ENOG4108V6E	Cell division protein mraZ
DRB99_RS10285	ENOG410890F	Dynamin family
DRB99_RS10315	ENOG410841Q	phosphoesterase PA-phosphatase related protein
DRB99_RS10325	ENOG410828M	hemerythrin-like, metal-binding protein
DRB99_RS10330	ENOG4105D22	carbon starvation protein
DRB99_RS10345	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
DRB99_RS10355	ENOG4105C26	Dehydrogenase
DRB99_RS10360	ENOG4105CFP	Peptidase U32
DRB99_RS10380	ENOG4107QJQ	Mate efflux family protein
DRB99_RS10400	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
DRB99_RS10425	ENOG4105VFE	sira family
DRB99_RS10430	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DRB99_RS10435	ENOG4105DWK	Membrane
DRB99_RS10465	ENOG4105C02	permease
DRB99_RS10480	ENOG4105D5G	Transposase
DRB99_RS10490	ENOG4105FE9	pseudouridine synthase
DRB99_RS10515	ENOG4105C5H	ABC transporter
DRB99_RS10525	ENOG4105I08	Pseudouridine synthase
DRB99_RS10540	ENOG4105C7B	Threonine dehydratase
DRB99_RS10550	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DRB99_RS10555	ENOG4105C02	permease
DRB99_RS10560	ENOG4105DBI	uridine monophosphokinase
DRB99_RS10570	ENOG4105EPR	degv family
DRB99_RS10600	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DRB99_RS10605	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DRB99_RS10610	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
DRB99_RS10615	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
DRB99_RS10625	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
DRB99_RS10630	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS10635	ENOG4108X4Q	Hydrolase
DRB99_RS10650	ENOG4108KGH	TRANSCRIPTIONal
DRB99_RS10665	ENOG4105BZ1	(ABC) transporter
DRB99_RS10675	ENOG4105D5G	Transposase
DRB99_RS10680	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
DRB99_RS10685	ENOG4107YJ4	chain length determinant protein
DRB99_RS10720	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
DRB99_RS10725	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
DRB99_RS10730	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
DRB99_RS10770	ENOG4105CG5	Glycosyl transferase (Group 1
DRB99_RS10775	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DRB99_RS10780	ENOG4105HTX	biosynthesis protein
DRB99_RS10790	ENOG4105D3Q	Sugar transferase
DRB99_RS10800	ENOG4108UQV	Membrane
DRB99_RS10805	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DRB99_RS10810	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
DRB99_RS10825	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
DRB99_RS10835	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DRB99_RS10855	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
DRB99_RS10865	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DRB99_RS10870	ENOG410810Y	Sulfite reductase
DRB99_RS10875	ENOG4107SHJ	sulfite reductase subunit b
DRB99_RS10880	ENOG4105D5B	Sulfite reductase, subunit A
DRB99_RS10895	ENOG4105BZU	Histidine kinase
DRB99_RS10900	ENOG4105C9M	aspartyl-trna synthetase
DRB99_RS10905	ENOG4105CUT	histidyl-tRNA synthetase
DRB99_RS10910	ENOG4105D4P	Coproporphyrinogen iii oxidase
DRB99_RS10915	ENOG4105C5X	domain protein
DRB99_RS10920	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
DRB99_RS10925	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DRB99_RS10930	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DRB99_RS10935	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DRB99_RS10940	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DRB99_RS10945	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DRB99_RS10965	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
DRB99_RS10970	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DRB99_RS10975	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DRB99_RS11035	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
DRB99_RS11140	ENOG4105UQX	Mate efflux family protein
DRB99_RS11145	ENOG4105DND	Transcriptional regulator
DRB99_RS11165	ENOG4108UHU	Aldolase
DRB99_RS11185	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
DRB99_RS11195	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
DRB99_RS11200	ENOG4108IUK	alpha amylase, catalytic
DRB99_RS11205	ENOG4105EG2	ABC transporter, permease
DRB99_RS11210	ENOG4105D56	permease protein
DRB99_RS11215	ENOG4107FKK	extracellular solute-binding protein family 1
DRB99_RS11220	ENOG4106HBX	Transcriptional Regulator AraC Family
DRB99_RS11225	ENOG4107RBB	ABC transporter, permease
DRB99_RS11230	ENOG4105C19	ABC transporter
DRB99_RS11245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS11255	ENOG4108UVJ	appr-1-p processing domain protein
DRB99_RS11260	ENOG4105KY8	Rubrerythrin
DRB99_RS11270	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DRB99_RS11290	ENOG4105DB7	PHP domain protein
DRB99_RS11295	ENOG4105DFM	M18 family aminopeptidase
DRB99_RS11300	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
DRB99_RS11340	ENOG4105C3R	Methionine synthase
DRB99_RS11350	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DRB99_RS11425	ENOG4105CS2	ec 3.2.1.21
DRB99_RS11430	ENOG4105C5Y	PTS System
DRB99_RS11435	ENOG4105CID	antiterminator
DRB99_RS11445	ENOG4105EI2	Pseudouridine synthase
DRB99_RS11455	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
DRB99_RS11475	ENOG4105DAP	Nicotinate phosphoribosyltransferase
DRB99_RS11490	ENOG4105G5W	regulator Fur family
DRB99_RS11520	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DRB99_RS11525	ENOG4108IUQ	atp-dependent protease
DRB99_RS11530	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DRB99_RS11540	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DRB99_RS11555	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DRB99_RS11560	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
DRB99_RS11565	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DRB99_RS11570	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DRB99_RS11575	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DRB99_RS11580	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DRB99_RS11585	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DRB99_RS11590	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DRB99_RS11595	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DRB99_RS11600	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DRB99_RS11625	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DRB99_RS11630	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS11645	ENOG41090I5	UPF0735 ACT domain-containing protein
DRB99_RS11650	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DRB99_RS11655	ENOG4107QID	Threonine synthase
DRB99_RS11675	ENOG4108HM4	ABC transporter
DRB99_RS11680	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
DRB99_RS11685	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DRB99_RS11690	ENOG4105D52	delta-aminolevulinic acid dehydratase
DRB99_RS11695	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DRB99_RS11710	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DRB99_RS11715	ENOG410810Y	Sulfite reductase
DRB99_RS11720	ENOG4105F4P	)-transporter
DRB99_RS11730	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DRB99_RS11735	ENOG410696E	Membrane
DRB99_RS11740	ENOG4105CVG	Homoserine O-transsuccinylase
DRB99_RS11745	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
DRB99_RS11750	ENOG4105CPN	adenine deaminase
DRB99_RS11760	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DRB99_RS11775	ENOG410667J	hydrolase
DRB99_RS11795	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DRB99_RS11800	ENOG4107QZB	decarboxylase
DRB99_RS11815	ENOG4105E4R	Precorrin-3B C17-methyltransferase
DRB99_RS11820	ENOG4108P62	biosynthesis protein (CbiG)
DRB99_RS11825	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
DRB99_RS11835	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
DRB99_RS11840	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
DRB99_RS11845	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
DRB99_RS11850	ENOG41081F0	Precorrin-8x methylmutase
DRB99_RS11855	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DRB99_RS11860	ENOG4107PPM	cobalt chelatase
DRB99_RS11875	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS11890	ENOG4105D9N	nucleoside
DRB99_RS11895	ENOG4105DRR	Transcriptional regulator, GntR family
DRB99_RS11905	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DRB99_RS11910	ENOG4108IUS	Transketolase
DRB99_RS11915	ENOG4108HHA	Transketolase
DRB99_RS11925	ENOG4105KG3	cytidine deaminase
DRB99_RS11930	ENOG4105D9N	nucleoside
DRB99_RS11935	ENOG4108I5U	Uridine phosphorylase
DRB99_RS11960	ENOG4108IUS	Transketolase
DRB99_RS11965	ENOG4108HHA	Transketolase
DRB99_RS11975	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
DRB99_RS11990	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
DRB99_RS12005	ENOG4105E98	transcriptional regulator DeoR family
DRB99_RS12010	ENOG4105C8J	)-transporter
DRB99_RS12020	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
DRB99_RS12060	ENOG4108IY8	ABC, transporter
DRB99_RS12065	ENOG4106FTQ	Taurine ABC transporter, periplasmic
DRB99_RS12070	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS12075	ENOG4107YHD	transcriptional regulator
DRB99_RS12090	ENOG4105BZU	Histidine kinase
DRB99_RS12095	ENOG4108UW5	maltose o-acetyltransferase
DRB99_RS12100	ENOG4105CG3	alpha amylase, catalytic region
DRB99_RS12105	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
DRB99_RS12120	ENOG4105CAH	Chromate
DRB99_RS12130	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DRB99_RS12145	ENOG4105P4J	Allophanate hydrolase, subunit 1
DRB99_RS12155	ENOG4105BZG	amino acid carrier protein
DRB99_RS12160	ENOG4105E7W	lamb ycsf family protein
DRB99_RS12165	ENOG4105CFM	UPF0317 protein
DRB99_RS12190	ENOG4105K56	Transcriptional regulator
DRB99_RS12195	ENOG4105CHM	Aminotransferase
DRB99_RS12200	ENOG4105C8J	)-transporter
DRB99_RS12235	ENOG4105KST	dependent repressor
DRB99_RS12245	ENOG4105CE1	Ferrous iron transport protein b
DRB99_RS12250	ENOG4105CN5	Metallo-Beta-Lactamase
DRB99_RS12260	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DRB99_RS12270	ENOG4105DR4	Methyltransferase
DRB99_RS12280	ENOG4108IUM	Glycogen debranching enzyme
DRB99_RS12285	ENOG4108IUK	alpha amylase, catalytic
DRB99_RS12290	ENOG4105PTM	secreted protein
DRB99_RS12305	ENOG4105CAH	Chromate
DRB99_RS12310	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
DRB99_RS12315	ENOG41080E8	Transcriptional regulator, Spx MgsR family
DRB99_RS12320	ENOG4108EUD	Lysophospholipase
DRB99_RS12325	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS12330	ENOG4105DHT	Metal Dependent Phosphohydrolase
DRB99_RS12345	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DRB99_RS12350	ENOG4105KG3	cytidine deaminase
DRB99_RS12360	ENOG4105UIB	(ABC) transporter
DRB99_RS12365	ENOG4108JQ9	ABC transporter
DRB99_RS12370	ENOG4107TFB	basic membrane
DRB99_RS12375	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS12380	ENOG4105CHM	Aminotransferase
DRB99_RS12385	ENOG4108ZB6	transcriptional regulator AsnC family
DRB99_RS12395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DRB99_RS12400	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
DRB99_RS12410	ENOG4105C8J	)-transporter
DRB99_RS12415	ENOG4105CXN	decarboxylase
DRB99_RS12420	ENOG4108J6I	peptidase, M16
DRB99_RS12425	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
DRB99_RS12445	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS12455	ENOG4105C19	ABC transporter
DRB99_RS12490	ENOG4108ZJ4	polysaccharide deacetylase
DRB99_RS12515	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DRB99_RS12520	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DRB99_RS12535	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
DRB99_RS12540	ENOG4105CZV	ABC transporter
DRB99_RS12550	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
DRB99_RS12565	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS12570	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
DRB99_RS12580	ENOG4107FB0	transcriptional regulator DeoR family
DRB99_RS12600	ENOG4105K56	Transcriptional regulator
DRB99_RS12605	ENOG4105K63	Thioredoxin
DRB99_RS12635	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DRB99_RS12660	ENOG4105DCG	PHP domain protein
DRB99_RS12665	ENOG4105C5I	Dehydrogenase
DRB99_RS12675	ENOG4108IUJ	4-alpha-glucanotransferase
DRB99_RS12680	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS12685	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
DRB99_RS12720	ENOG4105W8Z	4'-phosphopantetheinyl transferase
DRB99_RS12740	ENOG4107SQU	synthase
DRB99_RS12750	ENOG4105DXI	Major Facilitator superfamily
DRB99_RS12860	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRB99_RS12905	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS12910	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DRB99_RS12915	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
DRB99_RS12925	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DRB99_RS12945	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DRB99_RS12950	ENOG4107YR5	Diacylglycerol kinase
DRB99_RS12960	ENOG4105CTJ	Metal Dependent Phosphohydrolase
DRB99_RS12975	ENOG4105KTH	gatB Yqey
DRB99_RS12980	ENOG4105VCC	30S ribosomal protein S21
DRB99_RS12985	ENOG4107YU2	histidine triad (hIT) protein
DRB99_RS12990	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DRB99_RS12995	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DRB99_RS13000	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DRB99_RS13010	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
DRB99_RS13020	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DRB99_RS13025	ENOG4105CFG	Acts as a chaperone (By similarity)
DRB99_RS13030	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DRB99_RS13035	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
DRB99_RS13040	ENOG4105CSA	Coproporphyrinogen iii oxidase
DRB99_RS13060	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
DRB99_RS13065	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DRB99_RS13080	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DRB99_RS13090	ENOG4105CZ3	stage V sporulation protein ad
DRB99_RS13095	ENOG41090VF	Stage v sporulation protein ac
DRB99_RS13100	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS13105	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
DRB99_RS13110	ENOG41082AN	stage II sporulation protein
DRB99_RS13115	ENOG4105DAN	ATP-dependent protease
DRB99_RS13120	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DRB99_RS13150	ENOG4105CGA	flagellar basal-body rod protein FlgG
DRB99_RS13155	ENOG4105CGA	flagellar basal-body rod protein FlgG
DRB99_RS13165	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS13180	ENOG4105FZW	flagellar biosynthesis regulator FlhF
DRB99_RS13185	ENOG4105D7B	Flagellar biosynthesis protein flha
DRB99_RS13190	ENOG4105D00	flagellar biosynthetic protein flhB
DRB99_RS13200	ENOG4105CN7	Flagellar biosynthetic protein FliP
DRB99_RS13215	ENOG4106VK6	Flagellar motor protein
DRB99_RS13220	ENOG4105E14	MotA TolQ exbB proton channel
DRB99_RS13225	ENOG41068WV	flagellar FlbD family protein
DRB99_RS13230	ENOG4108JQA	flagellar
DRB99_RS13235	ENOG4108JQA	flagellar
DRB99_RS13270	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
DRB99_RS13275	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
DRB99_RS13280	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
DRB99_RS13285	ENOG4108ZC9	flagellar basal-body rod protein flgc
DRB99_RS13290	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
DRB99_RS13295	ENOG4105I03	Flagellin
DRB99_RS13320	ENOG4107RT6	flagellar hook-associated
DRB99_RS13340	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
DRB99_RS13345	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
DRB99_RS13350	ENOG4105DTJ	flagellar hook-associated protein
DRB99_RS13355	ENOG4105E1Q	flagellar hook-associated protein
DRB99_RS13370	ENOG4105DD5	Flagellar motor switch protein
DRB99_RS13375	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
DRB99_RS13380	ENOG4108V3W	Chemotaxis protein, CheW
DRB99_RS13385	ENOG4107YTP	response regulator receiver protein
DRB99_RS13390	ENOG4107PHP	CheC --inhibitor of MCP methylation
DRB99_RS13395	ENOG4105CBS	Chea signal transduction histidine kinase
DRB99_RS13400	ENOG4105BZU	Histidine kinase
DRB99_RS13405	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
DRB99_RS13415	ENOG4108V3W	Chemotaxis protein, CheW
DRB99_RS13425	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DRB99_RS13435	ENOG4105CHM	Aminotransferase
DRB99_RS13450	ENOG4105CS1	NAD(P)H quinone oxidoreductase
DRB99_RS13455	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DRB99_RS13460	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DRB99_RS13470	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRB99_RS13475	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRB99_RS13485	ENOG4105D82	Glutamate dehydrogenase
DRB99_RS13495	ENOG4107ZXI	Rhomboid family
DRB99_RS13500	ENOG4105DPN	Oligoendopeptidase f
DRB99_RS13515	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
DRB99_RS13520	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
DRB99_RS13530	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
DRB99_RS13535	ENOG4105FDK	ABC transporter
DRB99_RS13540	ENOG4105FAV	ABC, transporter
DRB99_RS13545	ENOG4105I3K	Ferric uptake regulator, Fur family
DRB99_RS13550	ENOG41081WW	Probably functions as a manganese efflux pump (By similarity)
DRB99_RS13555	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
DRB99_RS13560	ENOG4105C9B	Cysteine desulfurase
DRB99_RS13580	ENOG4105C5H	ABC transporter
DRB99_RS13585	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DRB99_RS13595	ENOG4105BZU	Histidine kinase
DRB99_RS13605	ENOG4105C2W	permease
DRB99_RS13620	ENOG4105BZU	Histidine kinase
DRB99_RS13630	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
DRB99_RS13640	ENOG4105FH5	Membrane
DRB99_RS13650	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
DRB99_RS13655	ENOG4105C08	Histidine kinase
DRB99_RS13690	ENOG4105CMT	Dihydroxyacetone kinase
DRB99_RS13700	ENOG4105DZ6	Band 7 protein
DRB99_RS13730	ENOG4105D01	(LipO)protein
DRB99_RS13735	ENOG4108UMI	ABC transporter, permease
DRB99_RS13740	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DRB99_RS13745	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DRB99_RS13750	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DRB99_RS13760	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DRB99_RS13770	ENOG4105KAF	membrAne
DRB99_RS13775	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DRB99_RS13790	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DRB99_RS13795	ENOG4105CP7	Triose-phosphate isomerase
DRB99_RS13800	ENOG4105BZA	Phosphoglycerate kinase
DRB99_RS13805	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DRB99_RS13815	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRB99_RS13825	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
DRB99_RS13830	ENOG41073R8	VanW family
DRB99_RS13840	ENOG4105BZU	Histidine kinase
DRB99_RS13850	ENOG4105CPF	Cell wall formation (By similarity)
DRB99_RS13855	ENOG4105CSM	endonuclease III
DRB99_RS13865	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
DRB99_RS13870	ENOG4105D7W	serine acetyltransferase
DRB99_RS13875	ENOG4105C6T	cysteine synthase
DRB99_RS13880	ENOG4105CJW	magnesium transporter
DRB99_RS13900	ENOG4105CBD	Diacylglycerol kinase
DRB99_RS13905	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
DRB99_RS13920	ENOG4108RAC	Rubrerythrin
DRB99_RS13925	ENOG4105ED1	spovr family
DRB99_RS13930	ENOG4106AKX	UPF0229 protein
DRB99_RS13935	ENOG4105CYN	Serine protein kinase
DRB99_RS13940	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
DRB99_RS13950	ENOG41090R9	glycosyltransferase
DRB99_RS13955	ENOG4107R51	Glycosyl transferase, family 2
DRB99_RS13960	ENOG41090R9	glycosyltransferase
DRB99_RS13970	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
DRB99_RS13980	ENOG4105CNI	cell division protein FtsW
DRB99_RS14085	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
DRB99_RS14090	ENOG4105DZ1	carboxypeptidase
DRB99_RS14095	ENOG4105EMS	pseudouridine synthase
DRB99_RS14100	ENOG4108KGH	TRANSCRIPTIONal
DRB99_RS14105	ENOG4108WF2	Metal Dependent Phosphohydrolase
DRB99_RS14110	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DRB99_RS14115	ENOG410812S	Rna-binding protein
DRB99_RS14120	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DRB99_RS14125	ENOG4105K46	50S ribosomal protein l27
DRB99_RS14135	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DRB99_RS14140	ENOG4105C03	ribonuclease
DRB99_RS14170	ENOG4105CNI	cell division protein FtsW
DRB99_RS14175	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
DRB99_RS14180	ENOG4107QMS	site-determining protein
DRB99_RS14190	ENOG4105PW4	Sugar fermentation stimulation protein homolog
DRB99_RS14205	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
DRB99_RS14210	ENOG4105DFF	Rod shape-determining protein mreb
DRB99_RS14215	ENOG4105W5Q	DNA repair protein (RadC
DRB99_RS14220	ENOG4108Z03	MAF-like protein
DRB99_RS14235	ENOG4105CIN	aminoacyl-histidine dipeptidase
DRB99_RS14245	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DRB99_RS14260	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DRB99_RS14265	ENOG4106I4J	membrane
DRB99_RS14275	ENOG4105DSE	periplasmic solute binding protein
DRB99_RS14310	ENOG4105KME	endoribonuclease L-psp
DRB99_RS14335	ENOG4105K8N	protein family UPF0079, ATPase
DRB99_RS14340	ENOG41072GX	Peptidase M22 Glycoprotease
DRB99_RS14345	ENOG410801F	ribosomal-protein-alanine acetyltransferase
DRB99_RS14370	ENOG4105BZU	Histidine kinase
DRB99_RS14395	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DRB99_RS14400	ENOG4105MS2	ribosomal subunit Interface protein
DRB99_RS14405	ENOG4105MJ2	Competence protein
DRB99_RS14415	ENOG4105C7H	Helicase, RecD TraA family
DRB99_RS14465	ENOG4108ZDA	Sporulation protein YyaC
DRB99_RS14475	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
DRB99_RS14490	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DRB99_RS14505	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DRB99_RS14525	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
DRB99_RS14530	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DRB99_RS14535	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
DRB99_RS14545	ENOG4105CHU	acetyl-coa acetyltransferase
DRB99_RS14550	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
DRB99_RS14560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DRB99_RS14565	ENOG4108YZG	isomerase
DRB99_RS14570	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DRB99_RS14580	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DRB99_RS14590	ENOG4107104	thymidine kinase
DRB99_RS14595	ENOG41082DI	50s ribosomal protein l31
DRB99_RS14600	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
DRB99_RS14605	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DRB99_RS14610	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DRB99_RS14630	ENOG4108ZXQ	stage ii sporulation protein r
DRB99_RS14635	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DRB99_RS14655	ENOG4105W42	Veg protein
DRB99_RS14660	ENOG4105XFA	sporulation peptidase YabG
DRB99_RS14670	ENOG4108TJN	glycosyl transferase group 1
DRB99_RS14690	ENOG4108TJN	glycosyl transferase group 1
DRB99_RS14705	ENOG4105VCP	PTS System
DRB99_RS14710	ENOG4105C0H	protease
DRB99_RS14720	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DRB99_RS14735	ENOG4105C3M	thioredoxin reductase
DRB99_RS14745	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
DRB99_RS14750	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
DRB99_RS14755	ENOG4108P49	AntiSigma factor
DRB99_RS14760	ENOG4105JVQ	RNA Polymerase
DRB99_RS14790	ENOG4105C9K	Endothelin-converting enzyme 1
DRB99_RS14830	ENOG4105D2N	Aldolase
DRB99_RS14840	ENOG4105E70	isomerase
DRB99_RS14850	ENOG4105F3R	pts system mannose fructose sorbose family iid
DRB99_RS14855	ENOG4105ETZ	PTS System
DRB99_RS14860	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
DRB99_RS14865	ENOG4105CE4	GlcNAc 6-P deacetylase
DRB99_RS14870	ENOG4105RD7	BadF BadG BcrA BcrD
DRB99_RS14875	ENOG4108JP0	extracellular solute-binding protein family 1
DRB99_RS14880	ENOG4105CT8	Phosphorylase
DRB99_RS14895	ENOG4105W4W	Transcriptional regulator
DRB99_RS15015	ENOG4105DIB	Oligopeptide-binding protein
DRB99_RS15045	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DRB99_RS15060	ENOG4105E4C	Lytic transglycosylase catalytic
DRB99_RS15070	ENOG4107XJU	UPF0178 protein
DRB99_RS15075	ENOG4107QYV	phosphohexose isomerase
DRB99_RS15105	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DRB99_RS15115	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DRB99_RS15120	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DRB99_RS15140	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DRB99_RS15150	ENOG4105BZJ	Electron transfer flavoprotein
DRB99_RS15155	ENOG4105C1G	acyl-Coa dehydrogenase
DRB99_RS15160	ENOG4105E39	Enoyl-CoA hydratase
DRB99_RS15165	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
DRB99_RS15175	ENOG4105C59	p-type ATPase
DRB99_RS15190	ENOG4105CK1	PTS System
DRB99_RS15200	ENOG4105RD7	BadF BadG BcrA BcrD
DRB99_RS15205	ENOG4105VCP	PTS System
DRB99_RS15210	ENOG4105VZJ	PTS System
DRB99_RS15215	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DRB99_RS15220	ENOG4105CE4	GlcNAc 6-P deacetylase
DRB99_RS15230	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
DRB99_RS15235	ENOG4105CXY	transporter
DRB99_RS15250	ENOG4105BZU	Histidine kinase
DRB99_RS15255	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DRB99_RS15270	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DRB99_RS15275	ENOG4105CQB	FAD linked oxidase domain protein
DRB99_RS15280	ENOG4105C10	Electron transfer flavoprotein
DRB99_RS15285	ENOG4105BZJ	Electron transfer flavoprotein
DRB99_RS15290	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DRB99_RS15300	ENOG4107QW8	radical SAM domain protein
DRB99_RS15310	ENOG4107BJW	polysaccharide deacetylase
DRB99_RS15320	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DRB99_RS15355	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
DRB99_RS15365	ENOG4108QTI	)-transporter
DRB99_RS15370	ENOG4108IUK	alpha amylase, catalytic
DRB99_RS15375	ENOG410874W	AraC family transcriptional regulator
DRB99_RS15380	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
DRB99_RS15395	ENOG4105D07	Signal peptide peptidase, SppA
DRB99_RS15400	ENOG4108V2W	Carbonate dehydratase
DRB99_RS15410	ENOG4105DE4	1-phosphofructokinase
DRB99_RS15415	ENOG4105D2N	Aldolase
DRB99_RS15425	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
DRB99_RS15430	ENOG4105DT3	PTS system, galactitol-specific IIc component
DRB99_RS15445	ENOG4105E98	transcriptional regulator DeoR family
DRB99_RS15450	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DRB99_RS15485	ENOG4105CI1	PTS System
DRB99_RS15495	ENOG4105FKQ	transcriptional regulator
DRB99_RS15500	ENOG4108IUJ	4-alpha-glucanotransferase
DRB99_RS15525	ENOG4105C7K	acetolactate synthase
DRB99_RS15535	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DRB99_RS15540	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DRB99_RS15545	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DRB99_RS15550	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DRB99_RS15555	ENOG4108ZP8	Acetolactate synthase small subunit
DRB99_RS15565	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DRB99_RS15570	ENOG4105KGF	protein, YerC YecD
DRB99_RS15590	ENOG4105NA0	Transcriptional regulator
DRB99_RS15595	ENOG4105C3S	Mate efflux family protein
DRB99_RS15600	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS15615	ENOG4107RE7	phosphate butyryltransferase
DRB99_RS15620	ENOG4105DZ0	fad dependent oxidoreductase
DRB99_RS15630	ENOG4105C8B	TIGR00159 family
DRB99_RS15640	ENOG4105DYB	Isoaspartyl dipeptidase
DRB99_RS15650	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DRB99_RS15655	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DRB99_RS15660	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DRB99_RS15680	ENOG4107AYK	membrAne
DRB99_RS15690	ENOG4107GFK	fumarate
DRB99_RS15695	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DRB99_RS15700	ENOG4105EAM	Na Pi-cotransporter
DRB99_RS15710	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DRB99_RS15715	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DRB99_RS15720	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
DRB99_RS15725	ENOG4108JJB	ABC transporter
DRB99_RS15730	ENOG4108JJB	ABC transporter
DRB99_RS15735	ENOG4108ZT0	50S ribosomal protein l17
DRB99_RS15740	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DRB99_RS15745	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DRB99_RS15750	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DRB99_RS15755	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DRB99_RS15760	ENOG41067V7	50S ribosomal protein L36
DRB99_RS15765	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DRB99_RS15780	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DRB99_RS15785	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DRB99_RS15790	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DRB99_RS15795	ENOG41084RK	50S ribosomal protein L30
DRB99_RS15805	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DRB99_RS15810	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DRB99_RS15815	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DRB99_RS15825	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DRB99_RS15830	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DRB99_RS15835	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DRB99_RS15840	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DRB99_RS15845	ENOG41082SA	50s ribosomal protein l29
DRB99_RS15850	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DRB99_RS15855	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DRB99_RS15860	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DRB99_RS15865	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DRB99_RS15870	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DRB99_RS15875	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DRB99_RS15880	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DRB99_RS15885	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DRB99_RS15890	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DRB99_RS15895	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DRB99_RS15900	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DRB99_RS15915	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DRB99_RS15925	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DRB99_RS15935	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DRB99_RS15940	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DRB99_RS15945	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DRB99_RS15950	ENOG410683Z	Preprotein translocase SecE subunit
DRB99_RS15955	ENOG4105WDJ	50S ribosomal protein L33
DRB99_RS15960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DRB99_RS15970	ENOG4105QIV	RNA polymerase
DRB99_RS15980	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DRB99_RS15985	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DRB99_RS15990	ENOG4105C8N	cysteinyl-tRNA synthetase
DRB99_RS15995	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DRB99_RS16000	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DRB99_RS16005	ENOG4105CTP	PilT protein domain protein
DRB99_RS16015	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
DRB99_RS16020	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DRB99_RS16050	ENOG4108Z0C	Uvrb UvrC protein
DRB99_RS16060	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
DRB99_RS16065	ENOG41084EF	Ferredoxin
DRB99_RS16075	ENOG4105MA4	psp1 domain protein
DRB99_RS16085	ENOG4105X0R	protein from nitrogen regulatory protein P-II
DRB99_RS16090	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DRB99_RS16150	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DRB99_RS16155	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DRB99_RS16180	ENOG4105CRK	lysyL-tRNA synthetase
DRB99_RS16185	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DRB99_RS16190	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DRB99_RS16195	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
DRB99_RS16200	ENOG4105CKU	formyltetrahydrofolate synthetase
DRB99_RS16205	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DRB99_RS16210	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
DRB99_RS16215	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DRB99_RS16275	ENOG41060GV	RNA binding s1 domain protein
DRB99_RS16295	ENOG41082I2	s4 domain protein
DRB99_RS16305	ENOG4108IY2	MazG family
DRB99_RS16315	ENOG4108M14	stage v sporulation protein t
DRB99_RS16325	ENOG4108JA2	transcriptioN-repair coupling factor
DRB99_RS16330	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DRB99_RS16335	ENOG4105BZU	Histidine kinase
DRB99_RS16340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS16350	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DRB99_RS16355	ENOG4105K4W	Could be involved in septation (By similarity)
DRB99_RS16360	ENOG4105DFT	pur operon repressor
DRB99_RS16365	ENOG4105DFU	Cell wall formation (By similarity)
DRB99_RS16390	ENOG4108VX5	3-methyladenine DNA glycosylase
DRB99_RS16400	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
DRB99_RS16405	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DRB99_RS16410	ENOG4107SDT	Homocitrate synthase
DRB99_RS16415	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
DRB99_RS16420	ENOG4105EPR	degv family
DRB99_RS16435	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
DRB99_RS16470	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
DRB99_RS16475	ENOG41069ER	domain protein
DRB99_RS16480	ENOG4105F8V	Hydrolase, tatD family
DRB99_RS16485	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DRB99_RS16500	ENOG4107S6Z	Na H antiporter
DRB99_RS16505	ENOG4107RAQ	aminopeptidase
DRB99_RS16515	ENOG4108JIC	nucleoside recognition domain protein
DRB99_RS16525	ENOG4105UQX	Mate efflux family protein
DRB99_RS16565	ENOG4105US7	Histidine kinase
DRB99_RS16570	ENOG4108STX	response regulator
DRB99_RS16590	ENOG4108N5B	2-phosphosulfolactate phosphatase
DRB99_RS16595	ENOG4105N5T	Radical SAM Protein
DRB99_RS16600	ENOG4108K88	Membrane
DRB99_RS16620	ENOG41069ER	domain protein
DRB99_RS16635	ENOG4107ZE5	PPIases accelerate the folding of proteins
DRB99_RS16645	ENOG4105C5F	glutamine synthetase
DRB99_RS16650	ENOG4105CPI	Metal Dependent Phosphohydrolase
DRB99_RS16670	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS16680	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DRB99_RS16690	ENOG4105DWD	nucleoside recognition domain protein
DRB99_RS16695	ENOG4108UT2	hemolysin iii
DRB99_RS16710	ENOG4105C5H	ABC transporter
DRB99_RS16715	ENOG4105J7I	hydrolase
DRB99_RS16730	ENOG4105DJ4	phosphatidylserine decarboxylase
DRB99_RS16745	ENOG4105BZU	Histidine kinase
DRB99_RS16760	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
DRB99_RS16765	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
DRB99_RS16770	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DRB99_RS16800	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DRB99_RS16815	ENOG4108Z3G	3H domain protein
DRB99_RS16845	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRB99_RS16850	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRB99_RS16860	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DRB99_RS16870	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DRB99_RS16875	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DRB99_RS16880	ENOG4105VG0	50S ribosomal protein l34
DRB99_RS16885	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
DRB99_RS16890	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DRB99_RS16905	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
DRB99_RS16910	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
DRB99_RS16925	ENOG4107QJE	Chromosome Partitioning Protein
DRB99_RS16930	ENOG4105FA0	parb-like partition protein
DRB99_RS16940	ENOG4108ZDA	Sporulation protein YyaC
DRB99_RS16945	ENOG4105C9B	Cysteine desulfurase
DRB99_RS16960	ENOG4105D8X	mechanosensitive ion channel
DRB99_RS16970	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
DRB99_RS16975	ENOG4108UUM	single-stranded DNA-binding protein
DRB99_RS16980	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DRB99_RS16990	ENOG4105BZR	domain protein
DRB99_RS16995	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DRB99_RS17000	ENOG4108IUQ	atp-dependent protease
DRB99_RS17005	ENOG4105CDU	Replicative dna helicase
DRB99_RS17015	ENOG4105II7	pyrroline-5-carboxylate reductase
DRB99_RS17020	ENOG4105C6K	Malic enzyme
DRB99_RS17035	ENOG4105C09	Bile acid
DRB99_RS17045	ENOG4105CBX	hi0933 family
DRB99_RS17120	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DRB99_RS17150	ENOG4105Q2H	domain protein
DRB99_RS17155	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DRB99_RS17170	ENOG4107GRR	phosphate transport regulator
DRB99_RS17175	ENOG4105CJ3	phosphate transporter
DRB99_RS17180	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
DRB99_RS17200	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
DRB99_RS17205	ENOG4105VCP	PTS System
DRB99_RS17215	ENOG4105CK1	PTS System
DRB99_RS17220	ENOG4108S3Y	transcriptional regulator
DRB99_RS17225	ENOG4105CS2	ec 3.2.1.21
DRB99_RS17230	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
DRB99_RS17235	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
DRB99_RS17250	ENOG4105C8I	hydrolase, family 38
DRB99_RS17255	ENOG4108MCI	Transcriptional regulator, ARAC family
DRB99_RS17285	ENOG4108Q3X	Transcriptional regulator
DRB99_RS17290	ENOG410901P	UPF0249 protein
DRB99_RS17295	ENOG4105CI1	PTS System
DRB99_RS17300	ENOG4105F8D	glycoside hydrolase family 4
DRB99_RS17310	ENOG4108QTI	)-transporter
DRB99_RS17315	ENOG4105C6N	Formate acetyltransferase
DRB99_RS17320	ENOG4105F1A	Pyruvate formate-lyase
DRB99_RS17340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS17345	ENOG41062D9	Histidine kinase
DRB99_RS17350	ENOG4105VUF	Transcriptional regulator
DRB99_RS17360	ENOG4107RSM	transcriptional regulator
DRB99_RS17375	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
DRB99_RS17390	ENOG4105X5K	response regulator receiver protein
DRB99_RS17410	ENOG410667J	hydrolase
DRB99_RS17420	ENOG4105CJW	magnesium transporter
DRB99_RS17435	ENOG4105D5G	Transposase
DRB99_RS17485	ENOG4105BZ1	(ABC) transporter
DRB99_RS17495	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DRB99_RS17500	ENOG4107Y3V	-acetyltransferase
DRB99_RS17515	ENOG4105DND	Transcriptional regulator
DRB99_RS17520	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
DRB99_RS17525	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS17530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS17540	ENOG4108S9F	abc transporter, atp-binding protein
DRB99_RS17560	ENOG4105CI1	PTS System
DRB99_RS17570	ENOG4107YX5	Pfam:DUF548
DRB99_RS17590	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DRB99_RS17595	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS17600	ENOG4107QMU	Mate efflux family protein
DRB99_RS17605	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
DRB99_RS17615	ENOG41067MG	lrgb family
DRB99_RS17625	ENOG41073TP	transcriptional regulator
DRB99_RS17630	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
DRB99_RS17640	ENOG4108IY8	ABC, transporter
DRB99_RS17650	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS17655	ENOG4107XKF	NMT1 THI5 Like Domain Protein
DRB99_RS17665	ENOG4107SJI	Dehydrogenase
DRB99_RS17680	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DRB99_RS17695	ENOG4105BZU	Histidine kinase
DRB99_RS17710	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
DRB99_RS17720	ENOG4108Q3X	Transcriptional regulator
DRB99_RS17725	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
DRB99_RS17735	ENOG4105BZU	Histidine kinase
DRB99_RS17750	ENOG4105G0J	serine threonine protein kinase
DRB99_RS17760	ENOG4105C5Y	PTS System
DRB99_RS17765	ENOG4105CG3	alpha amylase, catalytic region
DRB99_RS17770	ENOG4107414	GntR family transcriptional regulator
DRB99_RS17775	ENOG4105CNW	domain protein
DRB99_RS17780	ENOG4105DQR	SNARE associated Golgi
DRB99_RS17805	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DRB99_RS17815	ENOG4105BZU	Histidine kinase
DRB99_RS17820	ENOG4107XVH	Transcriptional regulator
DRB99_RS17835	ENOG41081I9	integral membrane protein
DRB99_RS17845	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DRB99_RS17850	ENOG4107TXC	Transcriptional regulator
DRB99_RS17885	ENOG4107RRE	RNA-directed DNA polymerase
DRB99_RS17900	ENOG4105BZ1	(ABC) transporter
DRB99_RS17905	ENOG4105BZ1	(ABC) transporter
DRB99_RS17920	ENOG4108RCR	degv family
DRB99_RS17935	ENOG4105I03	Flagellin
DRB99_RS17940	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DRB99_RS17945	ENOG4105EAM	Na Pi-cotransporter
DRB99_RS17955	ENOG4105DQ6	Transposase
DRB99_RS17960	ENOG4105G9B	Transcriptional regulator
DRB99_RS17970	ENOG4105S0E	allantoin catabolism protein
DRB99_RS17975	ENOG4105C5I	Dehydrogenase
DRB99_RS17995	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRB99_RS18005	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
DRB99_RS18015	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS18020	ENOG4105CDW	Resistance protein
DRB99_RS18030	ENOG4105C3S	Mate efflux family protein
DRB99_RS18040	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
DRB99_RS18050	ENOG4108W2Y	isochorismatase
DRB99_RS18060	ENOG4105KVH	Transcriptional regulator
DRB99_RS18075	ENOG4105C5I	Dehydrogenase
DRB99_RS18085	ENOG4108U5J	'-nucleotidase
DRB99_RS18105	ENOG4105BZU	Histidine kinase
DRB99_RS18125	ENOG4107QM2	Aldo Keto reductase
DRB99_RS18130	ENOG4106KNT	transcriptional regulator
DRB99_RS18145	ENOG4105RD7	BadF BadG BcrA BcrD
DRB99_RS18155	ENOG4105VCP	PTS System
DRB99_RS18160	ENOG4105F8D	glycoside hydrolase family 4
DRB99_RS18165	ENOG4105CK1	PTS System
DRB99_RS18170	ENOG4105VZJ	PTS System
DRB99_RS18195	ENOG4107TXC	Transcriptional regulator
DRB99_RS18235	ENOG4107RN3	metallophosphoesterase
DRB99_RS18285	ENOG4105BZU	Histidine kinase
DRB99_RS18335	ENOG4105EZV	Transcriptional regulator
DRB99_RS18350	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DRB99_RS18375	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DRB99_RS18380	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
DRB99_RS18385	ENOG4108MDK	Dehydrogenase
DRB99_RS18395	ENOG4105CB5	ATP-dependent DNA helicase recG
DRB99_RS18405	ENOG4108TVT	permease
DRB99_RS18430	ENOG4107S1Q	Phosphatase
DRB99_RS18445	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
DRB99_RS18485	ENOG4105G7B	Protein of unknown function (DUF2992)
DRB99_RS18505	ENOG4107QJQ	Mate efflux family protein
DRB99_RS18515	ENOG4105DQR	SNARE associated Golgi
DRB99_RS18535	ENOG4105UIB	(ABC) transporter
DRB99_RS18540	ENOG4108JQ9	ABC transporter
DRB99_RS18550	ENOG4106IUH	DTW domain containing protein
DRB99_RS18560	ENOG41082BM	Transcriptional regulator, arsr family
DRB99_RS18565	ENOG4108589	degv family
DRB99_RS18570	ENOG4105EJ2	Transcriptional regulator
DRB99_RS18575	ENOG410667J	hydrolase
DRB99_RS18585	ENOG4105F3R	pts system mannose fructose sorbose family iid
DRB99_RS18610	ENOG4105WH1	Two component transcriptional regulator luxr family
DRB99_RS18615	ENOG4105BZU	Histidine kinase
DRB99_RS18640	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
DRB99_RS18645	ENOG4105CT1	(ABC) transporter
DRB99_RS18650	ENOG4105CDA	abc transporter atp-binding protein
DRB99_RS18655	ENOG4105DRP	amino acid AbC transporter
DRB99_RS18660	ENOG4105E5Q	amino acid AbC transporter
DRB99_RS18665	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
DRB99_RS18670	ENOG4105CK2	sodium dicarboxylate symporter
DRB99_RS18675	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
DRB99_RS18680	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
DRB99_RS18685	ENOG4105E0C	molybdate abc transporter
DRB99_RS18690	ENOG4108IJ6	ABC transporter
DRB99_RS18695	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS18700	ENOG4105VCP	PTS System
DRB99_RS18705	ENOG4105CK1	PTS System
DRB99_RS18715	ENOG4105CS2	ec 3.2.1.21
DRB99_RS18720	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
DRB99_RS18730	ENOG4107KJX	Transcriptional regulator
DRB99_RS18745	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
DRB99_RS18760	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
DRB99_RS18765	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DRB99_RS18770	ENOG4107UUR	Chlorohydrolase aminohydrolase
DRB99_RS18795	ENOG4107RCH	Diaminopropionate ammonia-lyase
DRB99_RS18800	ENOG4107QUY	Guanine deaminase
DRB99_RS18805	ENOG4105BZ1	(ABC) transporter
DRB99_RS18825	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
DRB99_RS18830	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
DRB99_RS18835	ENOG4108JE9	extracellular solute-binding protein family 1
DRB99_RS18840	ENOG4108HCJ	Hydrolase
DRB99_RS18845	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
DRB99_RS18860	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DRB99_RS18870	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS18875	ENOG4105DY9	regulatoR
DRB99_RS18890	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DRB99_RS18900	ENOG4105NAE	bifunctional deaminase-reductase domain protein
DRB99_RS18905	ENOG41086D8	Transcriptional regulator
DRB99_RS18930	ENOG4107XGZ	Hydrolase
DRB99_RS18940	ENOG4107QMZ	Dehydrogenase
DRB99_RS18965	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DRB99_RS18970	ENOG4105CW7	secretion protein, HlyD family
DRB99_RS18985	ENOG4105DQ6	Transposase
DRB99_RS18990	ENOG4107DB1	DUF218 domain
DRB99_RS19005	ENOG4108ZJ4	polysaccharide deacetylase
DRB99_RS19015	ENOG4108R5S	membrane
DRB99_RS19040	ENOG4105C5Q	Transcriptional regulator
DRB99_RS19080	ENOG4108W2Y	isochorismatase
DRB99_RS19100	ENOG4105DY9	regulatoR
DRB99_RS19110	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DRB99_RS19115	ENOG4105BZU	Histidine kinase
DRB99_RS19120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS19135	ENOG4105C4C	beta-galactosidase
DRB99_RS19150	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS19160	ENOG4107VQW	regulatoR
DRB99_RS19165	ENOG4105C2F	Histidine kinase
DRB99_RS19195	ENOG4105E0A	ABC, transporter
DRB99_RS19200	ENOG4105EHG	Permease protein
DRB99_RS19205	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
DRB99_RS19210	ENOG4107QJQ	Mate efflux family protein
DRB99_RS19220	ENOG4108MCI	Transcriptional regulator, ARAC family
DRB99_RS19230	ENOG4108Q3X	Transcriptional regulator
DRB99_RS19235	ENOG4108Q3X	Transcriptional regulator
DRB99_RS19240	ENOG4105CI1	PTS System
DRB99_RS19245	ENOG4105F8D	glycoside hydrolase family 4
DRB99_RS19265	ENOG4105KVH	Transcriptional regulator
DRB99_RS19295	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DRB99_RS19315	ENOG4107FQ9	ethanolamine ammonia-lyase
DRB99_RS19320	ENOG4105CPD	ethanolamine ammonia-lyase
DRB99_RS19335	ENOG4105EDW	glycosyl transferase, family 39
DRB99_RS19365	ENOG4105CEC	DNA methylase N-4 N-6
DRB99_RS19380	ENOG4105D9R	oxidoreductase
DRB99_RS19385	ENOG4105EE0	oxidoreductase
DRB99_RS19395	ENOG4108JJB	ABC transporter
DRB99_RS19400	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
DRB99_RS19405	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
DRB99_RS19415	ENOG4105C8M	UPF0272 protein
DRB99_RS19420	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
DRB99_RS19440	ENOG41090FM	Phosphatase
DRB99_RS19445	ENOG4105BZ1	(ABC) transporter
DRB99_RS19450	ENOG4105BZ1	(ABC) transporter
DRB99_RS19470	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DRB99_RS19485	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DRB99_RS19495	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DRB99_RS19505	ENOG4105E2R	ROK family
DRB99_RS19510	ENOG4105CMG	Carbohydrate kinase
DRB99_RS19515	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DRB99_RS19565	ENOG4105BZU	Histidine kinase
DRB99_RS19570	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS19575	ENOG4108J2R	molybdopterin oxidoreductase
DRB99_RS19580	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRB99_RS19585	ENOG4105BZU	Histidine kinase
DRB99_RS19610	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS19615	ENOG410810Y	Sulfite reductase
DRB99_RS19620	ENOG4107SHJ	sulfite reductase subunit b
DRB99_RS19625	ENOG4105D5B	Sulfite reductase, subunit A
DRB99_RS19645	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
DRB99_RS19655	ENOG4108PJD	permease
DRB99_RS19665	ENOG4105MAX	Superoxide reductase
DRB99_RS19690	ENOG4105DZ2	Transcriptional regulator
DRB99_RS19695	ENOG410841Q	phosphoesterase PA-phosphatase related protein
DRB99_RS19715	ENOG4108V06	Glutathione peroxidase
DRB99_RS19720	ENOG4108V06	Glutathione peroxidase
DRB99_RS19735	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
DRB99_RS19740	ENOG4108JJB	ABC transporter
DRB99_RS19745	ENOG4108V4M	Cobalt abc transporter
DRB99_RS19750	ENOG4105BZU	Histidine kinase
DRB99_RS19765	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRB99_RS19775	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
DRB99_RS19795	ENOG4105D6U	Sodium Glutamate Symporter
DRB99_RS19805	ENOG4105DDN	Pentapeptide repeat-containing protein
DRB99_RS19825	ENOG4108JJB	ABC transporter
DRB99_RS19850	ENOG4105DFH	Transport of potassium into the cell (By similarity)
DRB99_RS19855	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
DRB99_RS19860	ENOG4105CPC	Aldo Keto reductase
DRB99_RS19870	ENOG4108MES	Periplasmic binding protein
DRB99_RS19875	ENOG4105DQ5	transport system permease protein
DRB99_RS19880	ENOG4105EHG	Permease protein
DRB99_RS19885	ENOG4105E0A	ABC, transporter
DRB99_RS19895	ENOG4108Z5V	transcriptional regulator, merr family
DRB99_RS19905	ENOG4105BZ1	(ABC) transporter
DRB99_RS19920	ENOG4105C2W	permease
DRB99_RS19925	ENOG4105DNP	FAD linked oxidase domain protein
DRB99_RS19930	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
DRB99_RS19935	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
DRB99_RS19945	ENOG4105WH1	Two component transcriptional regulator luxr family
DRB99_RS19985	ENOG4105ETZ	PTS System
DRB99_RS19990	ENOG4105F3R	pts system mannose fructose sorbose family iid
DRB99_RS20010	ENOG4105BZU	Histidine kinase
DRB99_RS20015	ENOG4108UZ3	Transporter
DRB99_RS20020	ENOG4108MCI	Transcriptional regulator, ARAC family
DRB99_RS20025	ENOG4105C8Q	Methyl-accepting chemotaxis
DRB99_RS20060	ENOG4105C2J	ABC transporter
DRB99_RS20065	ENOG4105CNN	ABC, transporter
DRB99_RS20070	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
DRB99_RS20080	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DRB99_RS20085	ENOG4105ETE	Transcriptional regulator (LacI family
DRB99_RS20090	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
DRB99_RS20095	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
DRB99_RS20105	ENOG4105BZU	Histidine kinase
DRB99_RS20110	ENOG4105VYW	UPF0251 protein
DRB99_RS20130	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
DRB99_RS20140	ENOG4108MCI	Transcriptional regulator, ARAC family
DRB99_RS20145	ENOG4105CJQ	hydrolase, family 31
DRB99_RS20170	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
DRB99_RS20175	ENOG4105CHR	reductase
DRB99_RS20180	ENOG4107YDN	peptide deformylase
DRB99_RS20185	ENOG4108IUW	ABC transporter
DRB99_RS20220	ENOG4107S6X	Glycosyl transferase, family 2
DRB99_RS20225	ENOG4105CF7	AraC family transcriptional regulator
DRB99_RS20230	ENOG4105BZ1	(ABC) transporter
DRB99_RS20235	ENOG4105BZ1	(ABC) transporter
DRB99_RS20255	ENOG4107QRI	Phosphoketolase
DRB99_RS20260	ENOG4105C2F	Histidine kinase
DRB99_RS20265	ENOG4105EQD	regulatoR
DRB99_RS20280	ENOG4105CG3	alpha amylase, catalytic region
DRB99_RS20315	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DRB99_RS20320	ENOG4105F4R	Transcriptional regulator mode
DRB99_RS20325	ENOG4108IJ6	ABC transporter
DRB99_RS20330	ENOG4105E0C	molybdate abc transporter
DRB99_RS20335	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
DRB99_RS20350	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
DRB99_RS20365	ENOG4108YZA	Nitrogen regulatory protein pii
DRB99_RS20385	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
DRB99_RS20390	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
DRB99_RS20415	ENOG4105T16	Transcriptional regulator (AraC family)
DRB99_RS20425	ENOG4105CMT	Dihydroxyacetone kinase
DRB99_RS20435	ENOG4105VDH	Dihydroxyacetone kinase
DRB99_RS20440	ENOG4108HRK	Histidine kinase
DRB99_RS20445	ENOG41075H3	AraC family transcriptional regulator
DRB99_RS20465	ENOG4105D3R	alkyl hydroperoxide reductase
DRB99_RS20480	ENOG4105C5Y	PTS System
DRB99_RS20490	ENOG4105F04	LysR family Transcriptional regulator
DRB99_RS20495	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
DRB99_RS20500	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DRB99_RS20530	ENOG4105E98	transcriptional regulator DeoR family
DRB99_RS20535	ENOG4105F1A	Pyruvate formate-lyase
DRB99_RS20550	ENOG4108Q3X	Transcriptional regulator
DRB99_RS20585	ENOG4105EY8	ABC transporter
DRB99_RS20685	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving