locus-tag	class	description
AZ909_RS00020	COG1827	regulation of RNA biosynthetic process
AZ909_RS00035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZ909_RS00055	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZ909_RS00060	COG1074	ATP-dependent DNA helicase activity
AZ909_RS00065	COG1376	ErfK ybiS ycfS ynhG family protein
AZ909_RS00080	COG2205	protein histidine kinase activity
AZ909_RS00080	COG0784	Response regulator, receiver
AZ909_RS00095	COG0688	phosphatidylethanolamine metabolic process
AZ909_RS00110	COG0561	phosphatase activity
AZ909_RS00115	COG0488	(ABC) transporter
AZ909_RS00135	COG3314	Sporulation integral membrane protein YlbJ
AZ909_RS00145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZ909_RS00155	COG3290	protein histidine kinase activity
AZ909_RS00155	COG0840	transmembrane signaling receptor activity
AZ909_RS00190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZ909_RS00205	COG3584	3D domain protein
AZ909_RS00205	COG3583	domain protein
AZ909_RS00225	COG3949	Membrane
AZ909_RS00230	COG1242	4 iron, 4 sulfur cluster binding
AZ909_RS00235	COG2045	Belongs to the ComB family
AZ909_RS00255	COG0745	RESPONSE REGULATOR receiver
AZ909_RS00260	COG5002	protein histidine kinase activity
AZ909_RS00300	COG0534	Mate efflux family protein
AZ909_RS00310	COG2715	membrane protein required for spore maturation
AZ909_RS00315	COG0700	Nucleoside recognition
AZ909_RS00320	COG0006	proline dipeptidase activity
AZ909_RS00325	COG1757	Na H antiporter
AZ909_RS00340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZ909_RS00345	COG0084	hydrolase, TatD family'
AZ909_RS00350	COG3583	domain protein
AZ909_RS00350	COG3584	3D domain protein
AZ909_RS00355	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AZ909_RS00390	COG1141	Ferredoxin
AZ909_RS00405	COG1307	EDD domain protein, DegV family
AZ909_RS00410	COG1328	CTP reductase activity
AZ909_RS00415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZ909_RS00420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZ909_RS00425	COG0602	queuosine metabolic process
AZ909_RS00435	COG2094	Belongs to the DNA glycosylase MPG family
AZ909_RS00455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZ909_RS00460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZ909_RS00465	COG2088	sporulation resulting in formation of a cellular spore
AZ909_RS00470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZ909_RS00480	COG0745	RESPONSE REGULATOR receiver
AZ909_RS00485	COG3850	Histidine kinase
AZ909_RS00485	COG5002	protein histidine kinase activity
AZ909_RS00490	COG0193	aminoacyl-tRNA hydrolase activity
AZ909_RS00495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZ909_RS00505	COG2002	toxin-antitoxin pair type II binding
AZ909_RS00510	COG2244	polysaccharide biosynthetic process
AZ909_RS00515	COG3956	TIGRFAM MazG family protein
AZ909_RS00525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZ909_RS00545	COG1098	S1 RNA binding domain
AZ909_RS00585	COG2208	phosphoserine phosphatase activity
AZ909_RS00590	COG0037	tRNA processing
AZ909_RS00595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AZ909_RS00600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZ909_RS00605	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AZ909_RS00610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZ909_RS00615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZ909_RS00620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZ909_RS00625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZ909_RS00640	COG0423	glycine-tRNA ligase activity
AZ909_RS00645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZ909_RS00695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZ909_RS00700	COG3870	Protein conserved in bacteria
AZ909_RS00710	COG1774	PSP1 C-terminal conserved region
AZ909_RS00725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZ909_RS00735	COG3880	PFAM UvrB UvrC protein
AZ909_RS00745	COG0542	response to heat
AZ909_RS00765	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AZ909_RS00770	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AZ909_RS00780	COG4956	integral membrane protein (PIN domain superfamily)
AZ909_RS00785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZ909_RS00790	COG0442	prolyl-tRNA aminoacylation
AZ909_RS00795	COG0215	cysteine-tRNA ligase activity
AZ909_RS00805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZ909_RS00825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZ909_RS00830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZ909_RS00835	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZ909_RS00845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZ909_RS00850	COG0081	regulation of translation
AZ909_RS00860	COG0222	ribosome binding
AZ909_RS00870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZ909_RS00885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZ909_RS00890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZ909_RS00895	COG0051	transcription antitermination factor activity, RNA binding
AZ909_RS00900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZ909_RS00905	COG0088	Forms part of the polypeptide exit tunnel
AZ909_RS00910	COG0089	rRNA binding
AZ909_RS00915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZ909_RS00920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZ909_RS00925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZ909_RS00930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZ909_RS00935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZ909_RS00940	COG0255	Belongs to the universal ribosomal protein uL29 family
AZ909_RS00945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZ909_RS00950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZ909_RS00955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZ909_RS00960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZ909_RS00970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZ909_RS00975	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZ909_RS00980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZ909_RS00990	COG1841	ribosomal large subunit assembly
AZ909_RS00995	COG0200	Binds to the 23S rRNA
AZ909_RS01000	COG0201	protein transport
AZ909_RS01005	COG0563	adenylate kinase activity
AZ909_RS01020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZ909_RS01025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZ909_RS01030	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZ909_RS01035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZ909_RS01040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZ909_RS01045	COG0202	RNA polymerase activity
AZ909_RS01050	COG0203	ribosomal protein L17
AZ909_RS01055	COG1122	ATPase activity
AZ909_RS01060	COG1122	ATPase activity
AZ909_RS01065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZ909_RS01070	COG0101	tRNA pseudouridine synthase activity
AZ909_RS01075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZ909_RS01085	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZ909_RS01090	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZ909_RS01095	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AZ909_RS01095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AZ909_RS01105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZ909_RS01125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZ909_RS01130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZ909_RS01135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZ909_RS01145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZ909_RS01155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZ909_RS01165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AZ909_RS01170	COG0280	phosphate acetyltransferase
AZ909_RS01190	COG0840	transmembrane signaling receptor activity
AZ909_RS01195	COG0534	Mate efflux family protein
AZ909_RS01220	COG4496	protein, YerC YecD
AZ909_RS01225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZ909_RS01235	COG0440	acetolactate synthase activity
AZ909_RS01240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZ909_RS01245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZ909_RS01250	COG0066	3-isopropylmalate dehydratase activity
AZ909_RS01255	COG0473	3-isopropylmalate dehydrogenase activity
AZ909_RS01265	COG0028	Belongs to the TPP enzyme family
AZ909_RS01295	COG1609	Transcriptional regulator
AZ909_RS01300	COG0366	Alpha amylase catalytic
AZ909_RS01305	COG1263	PTS System
AZ909_RS01305	COG2190	(PTS) system
AZ909_RS01305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS01350	COG1349	DNA-binding transcription factor activity
AZ909_RS01365	COG3775	system Galactitol-specific IIC component
AZ909_RS01370	COG0698	ribose 5-phosphate isomerase
AZ909_RS01385	COG1105	Belongs to the carbohydrate kinase PfkB family
AZ909_RS01395	COG0288	reversible hydration of carbon dioxide
AZ909_RS01400	COG0616	signal peptide processing
AZ909_RS01415	COG0058	SHG alpha-glucan phosphorylase activity
AZ909_RS01420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZ909_RS01420	COG2207	Transcriptional regulator
AZ909_RS01425	COG0366	Alpha amylase catalytic
AZ909_RS01430	COG2116	formate transmembrane transporter activity
AZ909_RS01440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZ909_RS01450	COG2873	o-acetylhomoserine
AZ909_RS01475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZ909_RS01485	COG0726	polysaccharide deacetylase
AZ909_RS01495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZ909_RS01505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ909_RS01510	COG2086	electron transfer activity
AZ909_RS01515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZ909_RS01520	COG0277	FAD linked oxidase domain protein
AZ909_RS01525	COG0653	protein targeting
AZ909_RS01540	COG0745	RESPONSE REGULATOR receiver
AZ909_RS01545	COG5002	protein histidine kinase activity
AZ909_RS01545	COG3850	Histidine kinase
AZ909_RS01565	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AZ909_RS01565	COG0662	Cupin 2, conserved barrel domain protein
AZ909_RS01570	COG2188	Transcriptional regulator
AZ909_RS01580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZ909_RS01580	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AZ909_RS01585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZ909_RS01590	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZ909_RS01595	COG2971	BadF BadG BcrA BcrD
AZ909_RS01605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZ909_RS01615	COG0640	Transcriptional regulator
AZ909_RS01620	COG2217	Heavy metal translocating P-type atpase
AZ909_RS01625	COG1971	Probably functions as a manganese efflux pump
AZ909_RS01630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AZ909_RS01635	COG1024	Enoyl-CoA hydratase
AZ909_RS01640	COG1960	acyl-CoA dehydrogenase activity
AZ909_RS01645	COG2086	electron transfer activity
AZ909_RS01655	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZ909_RS01675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZ909_RS01680	COG0459	protein refolding
AZ909_RS01690	COG0517	IMP dehydrogenase activity
AZ909_RS01690	COG0516	GMP reductase activity
AZ909_RS01705	COG1595	DNA-templated transcription, initiation
AZ909_RS01730	COG0166	Belongs to the GPI family
AZ909_RS01735	COG1671	Belongs to the UPF0178 family
AZ909_RS01745	COG0741	lytic transglycosylase activity
AZ909_RS01750	COG1187	pseudouridine synthase activity
AZ909_RS01760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZ909_RS01790	COG4166	transmembrane transport
AZ909_RS01880	COG2207	Transcriptional regulator
AZ909_RS01880	COG1917	Cupin 2, conserved barrel domain protein
AZ909_RS01885	COG1175	transmembrane transport
AZ909_RS01890	COG0395	ABC-type sugar transport system, permease component
AZ909_RS01895	COG5426	von Willebrand factor, type A
AZ909_RS01900	COG1653	transport
AZ909_RS01905	COG2971	BadF BadG BcrA BcrD
AZ909_RS01915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS01920	COG3715	PTS system
AZ909_RS01925	COG3716	PTS system mannose fructose sorbose family IID component
AZ909_RS01930	COG2188	Transcriptional regulator
AZ909_RS01935	COG2222	sugar isomerase
AZ909_RS01985	COG3590	peptidase
AZ909_RS02010	COG1595	DNA-templated transcription, initiation
AZ909_RS02020	COG0312	modulator of DNA gyrase
AZ909_RS02025	COG0312	modulator of DNA gyrase
AZ909_RS02050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZ909_RS02060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZ909_RS02065	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZ909_RS02115	COG4466	Protein conserved in bacteria
AZ909_RS02120	COG1388	LysM domain
AZ909_RS02120	COG0791	NLP P60 protein
AZ909_RS02125	COG4242	Belongs to the peptidase S51 family
AZ909_RS02135	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZ909_RS02160	COG0504	CTP synthase activity
AZ909_RS02165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZ909_RS02170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZ909_RS02175	COG0254	rRNA binding
AZ909_RS02180	COG1435	thymidine kinase activity
AZ909_RS02190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZ909_RS02200	COG0009	L-threonylcarbamoyladenylate synthase
AZ909_RS02205	COG0698	ribose 5-phosphate isomerase
AZ909_RS02210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZ909_RS02220	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZ909_RS02225	COG0183	Belongs to the thiolase family
AZ909_RS02240	COG0356	it plays a direct role in the translocation of protons across the membrane
AZ909_RS02245	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZ909_RS02250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZ909_RS02270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZ909_RS02290	COG2385	sporulation resulting in formation of a cellular spore
AZ909_RS02300	COG1609	Transcriptional regulator
AZ909_RS02345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZ909_RS02355	COG1040	competence protein
AZ909_RS02360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZ909_RS02365	COG0653	protein targeting
AZ909_RS02370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZ909_RS02390	COG5002	protein histidine kinase activity
AZ909_RS02400	COG2183	response to ionizing radiation
AZ909_RS02410	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AZ909_RS02415	COG0456	acetyltransferase
AZ909_RS02420	COG1214	PFAM Peptidase M22, glycoprotease
AZ909_RS02425	COG0802	atpase or kinase
AZ909_RS02450	COG0251	oxidation-reduction process
AZ909_RS02485	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZ909_RS02495	COG0670	Belongs to the BI1 family
AZ909_RS02500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZ909_RS02515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZ909_RS02515	COG0539	negative regulation of cytoplasmic translation
AZ909_RS02525	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZ909_RS02540	COG0424	maF-like protein
AZ909_RS02545	COG2003	Belongs to the UPF0758 family
AZ909_RS02550	COG1077	Cell shape determining protein MreB Mrl
AZ909_RS02555	COG1792	Involved in formation and maintenance of cell shape
AZ909_RS02570	COG1489	DNA binding
AZ909_RS02580	COG2894	cell division
AZ909_RS02585	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AZ909_RS02590	COG0772	Belongs to the SEDS family
AZ909_RS02620	COG1530	ribonuclease E activity
AZ909_RS02625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZ909_RS02635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZ909_RS02640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZ909_RS02645	COG1534	Rna-binding protein
AZ909_RS02650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZ909_RS02655	COG1713	HD superfamily hydrolase involved in NAD metabolism
AZ909_RS02660	COG1316	TRANSCRIPTIONal
AZ909_RS02665	COG0564	pseudouridine synthase activity
AZ909_RS02670	COG1686	Belongs to the peptidase S11 family
AZ909_RS02675	COG1555	photosystem II stabilization
AZ909_RS02705	COG0772	Belongs to the SEDS family
AZ909_RS02715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZ909_RS02720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZ909_RS02725	COG1442	glycosyl transferase family 8
AZ909_RS02730	COG1216	Glycosyl transferase, family 2
AZ909_RS02735	COG1442	glycosyl transferase family 8
AZ909_RS02745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZ909_RS02750	COG2766	serine protein kinase
AZ909_RS02755	COG2718	Belongs to the UPF0229 family
AZ909_RS02760	COG2719	SpoVR family
AZ909_RS02765	COG1592	Rubrerythrin
AZ909_RS02780	COG1183	phosphatidylcholine synthase activity
AZ909_RS02785	COG1597	lipid kinase activity
AZ909_RS02805	COG2239	Acts as a magnesium transporter
AZ909_RS02810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZ909_RS02815	COG1045	serine acetyltransferase
AZ909_RS02820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AZ909_RS02830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZ909_RS02835	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZ909_RS02845	COG5002	protein histidine kinase activity
AZ909_RS02855	COG2720	vancomycin resistance protein
AZ909_RS02860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZ909_RS02870	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZ909_RS02875	COG2390	Transcriptional regulator
AZ909_RS02880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZ909_RS02885	COG0126	phosphoglycerate kinase activity
AZ909_RS02890	COG0149	triose-phosphate isomerase activity
AZ909_RS02895	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AZ909_RS02910	COG0148	phosphopyruvate hydratase activity
AZ909_RS02920	COG3152	Membrane
AZ909_RS02940	COG0557	exoribonuclease II activity
AZ909_RS02945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZ909_RS02950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZ909_RS02955	COG2011	ABC-type metal ion transport system permease component
AZ909_RS02960	COG1464	Belongs to the NlpA lipoprotein family
AZ909_RS02995	COG2376	Dihydroxyacetone kinase
AZ909_RS03030	COG2205	protein histidine kinase activity
AZ909_RS03035	COG0745	RESPONSE REGULATOR receiver
AZ909_RS03045	COG4684	Psort location CytoplasmicMembrane, score
AZ909_RS03055	COG0037	tRNA processing
AZ909_RS03080	COG2233	PERMEase
AZ909_RS03085	COG2199	diguanylate cyclase activity
AZ909_RS03085	COG2203	Gaf domain
AZ909_RS03095	COG0756	dUTP diphosphatase activity
AZ909_RS03100	COG0488	(ABC) transporter
AZ909_RS03105	COG1309	transcriptional regulator
AZ909_RS03120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZ909_RS03125	COG0205	6-phosphofructokinase activity
AZ909_RS03130	COG1971	Probably functions as a manganese efflux pump
AZ909_RS03135	COG0735	belongs to the Fur family
AZ909_RS03140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZ909_RS03145	COG1121	(ABC) transporter
AZ909_RS03150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AZ909_RS03160	COG1696	Membrane protein involved in D-alanine export
AZ909_RS03165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZ909_RS03180	COG1164	Oligoendopeptidase f
AZ909_RS03185	COG0457	Tetratricopeptide repeat
AZ909_RS03185	COG0705	Rhomboid family
AZ909_RS03195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZ909_RS03200	COG1215	transferase activity, transferring glycosyl groups
AZ909_RS03205	COG0187	DNA topoisomerase II activity
AZ909_RS03210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZ909_RS03220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZ909_RS03220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZ909_RS03225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZ909_RS03230	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZ909_RS03245	COG0436	Aminotransferase
AZ909_RS03265	COG0835	chemotaxis
AZ909_RS03275	COG2201	protein-glutamate methylesterase activity
AZ909_RS03280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZ909_RS03285	COG0643	Histidine kinase
AZ909_RS03285	COG2198	Histidine kinase
AZ909_RS03290	COG1776	CheC inhibitor of MCP methylation
AZ909_RS03295	COG2201	protein-glutamate methylesterase activity
AZ909_RS03305	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZ909_RS03310	COG1776	CheC inhibitor of MCP methylation
AZ909_RS03310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZ909_RS03330	COG1256	bacterial-type flagellum assembly
AZ909_RS03330	COG4786	Flagellar basal body rod
AZ909_RS03335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZ909_RS03340	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AZ909_RS03345	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AZ909_RS03365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AZ909_RS03385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZ909_RS03390	COG1815	bacterial-type flagellum-dependent cell motility
AZ909_RS03400	COG1677	Flagellar hook-basal body complex protein FliE
AZ909_RS03405	COG1766	The M ring may be actively involved in energy transduction
AZ909_RS03410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZ909_RS03420	COG1157	protein secretion by the type III secretion system
AZ909_RS03445	COG4786	Flagellar basal body rod
AZ909_RS03450	COG4786	Flagellar basal body rod
AZ909_RS03455	COG1582	Flagellar protein (FlbD)
AZ909_RS03480	COG1338	Plays a role in the flagellum-specific transport system
AZ909_RS03490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZ909_RS03495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZ909_RS03500	COG1419	protein localization to endoplasmic reticulum
AZ909_RS03505	COG0455	bacterial-type flagellum organization
AZ909_RS03515	COG1191	sigma factor activity
AZ909_RS03525	COG4786	Flagellar basal body rod
AZ909_RS03530	COG4786	Flagellar basal body rod
AZ909_RS03545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZ909_RS03560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZ909_RS03565	COG1067	ATP-dependent peptidase activity
AZ909_RS03575	COG2172	sigma factor antagonist activity
AZ909_RS03590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZ909_RS03600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZ909_RS03615	COG0268	Binds directly to 16S ribosomal RNA
AZ909_RS03620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZ909_RS03645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZ909_RS03650	COG1420	regulation of RNA biosynthetic process
AZ909_RS03655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZ909_RS03660	COG0443	Heat shock 70 kDa protein
AZ909_RS03665	COG0484	heat shock protein binding
AZ909_RS03680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZ909_RS03690	COG2264	protein methyltransferase activity
AZ909_RS03695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZ909_RS03700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZ909_RS03705	COG0537	adenosine 5'-monophosphoramidase activity
AZ909_RS03710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZ909_RS03715	COG1610	YqeY-like protein
AZ909_RS03730	COG1480	7TM receptor with intracellular HD hydrolase
AZ909_RS03740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AZ909_RS03745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZ909_RS03760	COG0517	IMP dehydrogenase activity
AZ909_RS03765	COG0574	Belongs to the PEP-utilizing enzyme family
AZ909_RS03765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZ909_RS03780	COG0358	DNA primase activity
AZ909_RS03785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZ909_RS03815	COG3842	ATPase activity
AZ909_RS03820	COG3835	regulator
AZ909_RS03835	COG0058	SHG alpha-glucan phosphorylase activity
AZ909_RS03840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZ909_RS03845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZ909_RS03870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZ909_RS03890	COG0493	'glutamate synthase
AZ909_RS03900	COG3118	belongs to the thioredoxin family
AZ909_RS03905	COG1846	Transcriptional regulator
AZ909_RS03910	COG1114	Component of the transport system for branched-chain amino acids
AZ909_RS03925	COG1349	DNA-binding transcription factor activity
AZ909_RS03935	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AZ909_RS03955	COG1151	hydroxylamine reductase activity
AZ909_RS03965	COG1131	(ABC) transporter
AZ909_RS03970	COG1725	Transcriptional regulator
AZ909_RS03975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZ909_RS03985	COG0157	Belongs to the NadC ModD family
AZ909_RS03990	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZ909_RS04015	COG0726	polysaccharide deacetylase
AZ909_RS04040	COG0745	RESPONSE REGULATOR receiver
AZ909_RS04045	COG2205	protein histidine kinase activity
AZ909_RS04050	COG1136	(ABC) transporter
AZ909_RS04060	COG2199	diguanylate cyclase activity
AZ909_RS04060	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZ909_RS04075	COG0840	transmembrane signaling receptor activity
AZ909_RS04080	COG0612	Peptidase, M16
AZ909_RS04085	COG1982	Orn Lys Arg decarboxylase major
AZ909_RS04090	COG0733	neurotransmitter:sodium symporter activity
AZ909_RS04095	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZ909_RS04100	COG0542	response to heat
AZ909_RS04110	COG1522	sequence-specific DNA binding
AZ909_RS04115	COG0436	Aminotransferase
AZ909_RS04125	COG1744	ABC transporter substrate-binding protein PnrA-like
AZ909_RS04130	COG3845	ABC transporter
AZ909_RS04135	COG4603	Belongs to the binding-protein-dependent transport system permease family
AZ909_RS04140	COG1079	Belongs to the binding-protein-dependent transport system permease family
AZ909_RS04145	COG0295	cytidine deaminase activity
AZ909_RS04150	COG0813	purine-nucleoside phosphorylase activity
AZ909_RS04165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZ909_RS04170	COG3437	response regulator, receiver
AZ909_RS04175	COG2801	Transposase and inactivated derivatives
AZ909_RS04180	COG2267	carboxylic ester hydrolase activity
AZ909_RS04185	COG1393	Belongs to the ArsC family
AZ909_RS04190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZ909_RS04195	COG2059	Chromate
AZ909_RS04210	COG4086	secreted protein
AZ909_RS04215	COG0366	Alpha amylase catalytic
AZ909_RS04220	COG1523	belongs to the glycosyl hydrolase 13 family
AZ909_RS04230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZ909_RS04240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ909_RS04250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZ909_RS04255	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZ909_RS04265	COG1321	iron dependent repressor
AZ909_RS04300	COG0733	neurotransmitter:sodium symporter activity
AZ909_RS04305	COG0436	Aminotransferase
AZ909_RS04310	COG1846	Transcriptional regulator
AZ909_RS04320	COG1522	sequence-specific DNA binding
AZ909_RS04335	COG4336	lyase activity
AZ909_RS04340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZ909_RS04345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZ909_RS04350	COG1984	allophanate hydrolase subunit 2
AZ909_RS04355	COG0511	ligase activity, forming carbon-carbon bonds
AZ909_RS04360	COG0439	Biotin carboxylase
AZ909_RS04375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZ909_RS04385	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AZ909_RS04385	COG0028	Belongs to the TPP enzyme family
AZ909_RS04390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AZ909_RS04405	COG3290	protein histidine kinase activity
AZ909_RS04420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZ909_RS04420	COG0493	'glutamate synthase
AZ909_RS04425	COG2172	sigma factor antagonist activity
AZ909_RS04430	COG0840	transmembrane signaling receptor activity
AZ909_RS04460	COG1063	alcohol dehydrogenase
AZ909_RS04470	COG0493	'glutamate synthase
AZ909_RS04470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZ909_RS04475	COG2814	Major facilitator Superfamily
AZ909_RS04485	COG3142	Participates in the control of copper homeostasis
AZ909_RS04490	COG5002	protein histidine kinase activity
AZ909_RS04490	COG0642	Histidine kinase
AZ909_RS04495	COG0745	RESPONSE REGULATOR receiver
AZ909_RS04500	COG0398	Pfam SNARE associated Golgi protein
AZ909_RS04505	COG1183	phosphatidylcholine synthase activity
AZ909_RS04510	COG3290	protein histidine kinase activity
AZ909_RS04515	COG3279	Response regulator of the LytR AlgR family
AZ909_RS04520	COG1131	(ABC) transporter
AZ909_RS04535	COG3655	Transcriptional regulator
AZ909_RS04560	COG2731	YhcH YjgK YiaL family protein
AZ909_RS04585	COG0583	DNA-binding transcription factor activity
AZ909_RS04595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZ909_RS04600	COG3706	GGDEF domain
AZ909_RS04610	COG1115	amino acid carrier protein
AZ909_RS04615	COG1254	Belongs to the acylphosphatase family
AZ909_RS04620	COG0105	UTP biosynthetic process
AZ909_RS04630	COG1177	transmembrane transport
AZ909_RS04635	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZ909_RS04655	COG1115	amino acid carrier protein
AZ909_RS04660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZ909_RS04675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZ909_RS04685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ909_RS04690	COG1739	Uncharacterized protein family UPF0029
AZ909_RS04700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AZ909_RS04705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZ909_RS04710	COG1459	type II secretion system
AZ909_RS04760	COG0527	aspartate kinase activity
AZ909_RS04765	COG0004	ammonium transporteR
AZ909_RS04775	COG0347	Belongs to the P(II) protein family
AZ909_RS04790	COG0067	glutamate synthase
AZ909_RS04790	COG0069	glutamate synthase activity
AZ909_RS04790	COG0070	glutamate synthase
AZ909_RS04795	COG0493	'glutamate synthase
AZ909_RS04810	COG0583	DNA-binding transcription factor activity
AZ909_RS04820	COG0538	isocitrate dehydrogenase activity
AZ909_RS04835	COG2309	aminopeptidase activity
AZ909_RS04840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZ909_RS04840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZ909_RS04850	COG0741	lytic transglycosylase activity
AZ909_RS04880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZ909_RS04880	COG2199	diguanylate cyclase activity
AZ909_RS04885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZ909_RS04885	COG0512	Glutamine amidotransferase of anthranilate synthase
AZ909_RS04890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZ909_RS04895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZ909_RS04915	COG0745	RESPONSE REGULATOR receiver
AZ909_RS04915	COG2205	protein histidine kinase activity
AZ909_RS04915	COG3292	Two component regulator propeller
AZ909_RS04920	COG5002	protein histidine kinase activity
AZ909_RS04925	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AZ909_RS04935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZ909_RS04940	COG1116	anion transmembrane transporter activity
AZ909_RS04945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZ909_RS04965	COG1686	Belongs to the peptidase S11 family
AZ909_RS04975	COG3442	glutamine amidotransferase
AZ909_RS04980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZ909_RS04990	COG0826	peptidase U32
AZ909_RS04995	COG1193	negative regulation of DNA recombination
AZ909_RS05000	COG1683	Conserved Protein
AZ909_RS05005	COG0531	amino acid
AZ909_RS05015	COG0420	3'-5' exonuclease activity
AZ909_RS05020	COG0419	ATPase involved in DNA repair
AZ909_RS05025	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZ909_RS05030	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZ909_RS05035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZ909_RS05045	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AZ909_RS05050	COG0728	peptidoglycan biosynthetic process
AZ909_RS05060	COG0438	transferase activity, transferring glycosyl groups
AZ909_RS05085	COG0012	GTP binding
AZ909_RS05100	COG1968	undecaprenyl-diphosphatase activity
AZ909_RS05115	COG0540	Belongs to the ATCase OTCase family
AZ909_RS05130	COG0284	orotidine-5'-phosphate decarboxylase activity
AZ909_RS05140	COG0167	dihydroorotate dehydrogenase activity
AZ909_RS05145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZ909_RS05150	COG1882	Formate acetyltransferase
AZ909_RS05185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AZ909_RS05185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AZ909_RS05190	COG4632	Exopolysaccharide biosynthesis protein
AZ909_RS05190	COG5434	Belongs to the glycosyl hydrolase 28 family
AZ909_RS05200	COG1994	Peptidase M50
AZ909_RS05205	COG0018	arginyl-trna synthetase
AZ909_RS05210	COG0628	permease
AZ909_RS05230	COG0658	competence protein
AZ909_RS05230	COG2333	competence protein COMEC
AZ909_RS05245	COG2155	Conserved Protein
AZ909_RS05250	COG1522	sequence-specific DNA binding
AZ909_RS05280	COG0697	spore germination
AZ909_RS05285	COG0367	asparagine synthase
AZ909_RS05300	COG1728	Protein conserved in bacteria
AZ909_RS05325	COG1132	(ABC) transporter
AZ909_RS05335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZ909_RS05340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZ909_RS05340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZ909_RS05355	COG1301	dicarboxylic acid transport
AZ909_RS05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ909_RS05370	COG0765	amino acid transport
AZ909_RS05375	COG1126	abc transporter atp-binding protein
AZ909_RS05385	COG0038	chloride channel
AZ909_RS05390	COG1595	DNA-templated transcription, initiation
AZ909_RS05400	COG1027	Aspartate ammonia-lyase
AZ909_RS05410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZ909_RS05420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZ909_RS05425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZ909_RS05430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZ909_RS05435	COG0138	bifunctional purine biosynthesis protein purh
AZ909_RS05440	COG0151	Belongs to the GarS family
AZ909_RS05450	COG5002	protein histidine kinase activity
AZ909_RS05455	COG0393	Putative heavy-metal-binding
AZ909_RS05480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZ909_RS05490	COG2070	2-Nitropropane dioxygenase
AZ909_RS05495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZ909_RS05500	COG1028	Short-chain dehydrogenase reductase Sdr
AZ909_RS05505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZ909_RS05510	COG0511	ligase activity, forming carbon-carbon bonds
AZ909_RS05520	COG0439	Biotin carboxylase
AZ909_RS05525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZ909_RS05530	COG0825	malonyl-CoA metabolic process
AZ909_RS05545	COG4120	Belongs to the binding-protein-dependent transport system permease family
AZ909_RS05555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZ909_RS05560	COG1959	2 iron, 2 sulfur cluster binding
AZ909_RS05575	COG0482	sulfurtransferase activity
AZ909_RS05585	COG0628	permease
AZ909_RS05590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZ909_RS05595	COG4472	Bacterial protein of unknown function (DUF965)
AZ909_RS05600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZ909_RS05610	COG0735	belongs to the Fur family
AZ909_RS05615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZ909_RS05620	COG1217	gtp-binding protein TYPA
AZ909_RS05625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZ909_RS05630	COG4122	O-methyltransferase activity
AZ909_RS05635	COG0826	peptidase U32
AZ909_RS05660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZ909_RS05670	COG1191	sigma factor activity
AZ909_RS05675	COG1191	sigma factor activity
AZ909_RS05680	COG1873	PFAM PRC-barrel domain
AZ909_RS05685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZ909_RS05690	COG1496	oxidoreductase activity
AZ909_RS05695	COG0745	RESPONSE REGULATOR receiver
AZ909_RS05700	COG5002	protein histidine kinase activity
AZ909_RS05705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZ909_RS05710	COG0573	inorganic phosphate transmembrane transporter activity
AZ909_RS05715	COG0581	inorganic phosphate transmembrane transporter activity
AZ909_RS05720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZ909_RS05725	COG0704	Plays a role in the regulation of phosphate uptake
AZ909_RS05740	COG1160	GTP binding
AZ909_RS05745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZ909_RS05750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZ909_RS05770	COG2252	PERMEase
AZ909_RS05775	COG1561	YicC-like family, N-terminal region
AZ909_RS05790	COG1758	RNA polymerase activity
AZ909_RS05795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZ909_RS05800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZ909_RS05810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZ909_RS05815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZ909_RS05815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZ909_RS05820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZ909_RS05825	COG0631	protein serine/threonine phosphatase activity
AZ909_RS05835	COG1162	GTPase activity
AZ909_RS05840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZ909_RS05850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZ909_RS05860	COG1461	Dihydroxyacetone kinase
AZ909_RS05865	COG1609	Transcriptional regulator
AZ909_RS05870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZ909_RS05875	COG0742	ribosomal rna small subunit methyltransferase
AZ909_RS05880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZ909_RS05895	COG1323	Belongs to the UPF0348 family
AZ909_RS05900	COG0280	phosphate acetyltransferase
AZ909_RS05905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZ909_RS05920	COG0416	fatty acid biosynthetic process
AZ909_RS05930	COG0571	ribonuclease III activity
AZ909_RS05945	COG0552	protein localization to endoplasmic reticulum
AZ909_RS05950	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AZ909_RS05955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZ909_RS05960	COG0228	four-way junction DNA binding
AZ909_RS05970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZ909_RS05975	COG0336	Belongs to the RNA methyltransferase TrmD family
AZ909_RS05980	COG0335	large ribosomal subunit rRNA binding
AZ909_RS05985	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZ909_RS05990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZ909_RS06000	COG0606	chelatase, subunit chli
AZ909_RS06005	COG0758	DNA mediated transformation
AZ909_RS06010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZ909_RS06015	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AZ909_RS06020	COG0052	Belongs to the universal ribosomal protein uS2 family
AZ909_RS06030	COG0528	UMP kinase activity
AZ909_RS06045	COG4589	Belongs to the CDS family
AZ909_RS06050	COG0628	permease
AZ909_RS06080	COG0195	Participates in both transcription termination and antitermination
AZ909_RS06085	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AZ909_RS06095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZ909_RS06100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZ909_RS06115	COG0196	riboflavin kinase activity
AZ909_RS06120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZ909_RS06125	COG1185	polyribonucleotide nucleotidyltransferase activity
AZ909_RS06130	COG0612	Peptidase, M16
AZ909_RS06140	COG0527	aspartate kinase activity
AZ909_RS06150	COG0110	maltose O-acetyltransferase activity
AZ909_RS06155	COG3711	transcriptional antiterminator
AZ909_RS06160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS06160	COG1263	PTS System
AZ909_RS06160	COG2190	(PTS) system
AZ909_RS06170	COG0740	serine-type endopeptidase activity
AZ909_RS06180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZ909_RS06185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZ909_RS06190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZ909_RS06195	COG1418	mRNA catabolic process
AZ909_RS06200	COG2359	stage V sporulation protein S
AZ909_RS06205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZ909_RS06210	COG2155	Conserved Protein
AZ909_RS06215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZ909_RS06240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZ909_RS06240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZ909_RS06245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZ909_RS06255	COG1592	Rubrerythrin
AZ909_RS06255	COG1773	rubredoxin
AZ909_RS06260	COG3271	cysteine-type peptidase activity
AZ909_RS06260	COG2274	protein secretion by the type I secretion system
AZ909_RS06285	COG0348	domain, Protein
AZ909_RS06300	COG0745	RESPONSE REGULATOR receiver
AZ909_RS06305	COG2770	Histidine kinase
AZ909_RS06305	COG2205	protein histidine kinase activity
AZ909_RS06310	COG2364	Membrane
AZ909_RS06320	COG0347	Belongs to the P(II) protein family
AZ909_RS06325	COG1840	ABC-type Fe3 transport system, periplasmic component
AZ909_RS06330	COG3842	ATPase activity
AZ909_RS06335	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZ909_RS06340	COG1177	transmembrane transport
AZ909_RS06345	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AZ909_RS06350	COG1012	belongs to the aldehyde dehydrogenase family
AZ909_RS06370	COG1454	alcohol dehydrogenase
AZ909_RS06385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ909_RS06390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ909_RS06425	COG0534	Mate efflux family protein
AZ909_RS06435	COG0037	tRNA processing
AZ909_RS06445	COG0475	glutathione-regulated potassium exporter activity
AZ909_RS06465	COG3292	Two component regulator propeller
AZ909_RS06465	COG0745	RESPONSE REGULATOR receiver
AZ909_RS06465	COG2205	protein histidine kinase activity
AZ909_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
AZ909_RS06490	COG5002	protein histidine kinase activity
AZ909_RS06495	COG0745	RESPONSE REGULATOR receiver
AZ909_RS06500	COG0612	Peptidase, M16
AZ909_RS06525	COG5434	Belongs to the glycosyl hydrolase 28 family
AZ909_RS06525	COG4632	Exopolysaccharide biosynthesis protein
AZ909_RS06535	COG0534	Mate efflux family protein
AZ909_RS06555	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZ909_RS06560	COG1940	carbohydrate kinase activity
AZ909_RS06575	COG1619	proteins homologs of microcin C7 resistance protein MccF
AZ909_RS06580	COG1550	Protein conserved in bacteria
AZ909_RS06590	COG0861	Integral membrane protein TerC family
AZ909_RS06630	COG1523	belongs to the glycosyl hydrolase 13 family
AZ909_RS06635	COG2171	N-acyltransferase activity
AZ909_RS06640	COG0436	Aminotransferase
AZ909_RS06645	COG0601	transmembrane transport
AZ909_RS06650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZ909_RS06655	COG0444	Belongs to the ABC transporter superfamily
AZ909_RS06660	COG4608	Belongs to the ABC transporter superfamily
AZ909_RS06665	COG4166	transmembrane transport
AZ909_RS06675	COG3608	succinylglutamate desuccinylase aspartoacylase
AZ909_RS06685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZ909_RS06690	COG0747	negative chemotaxis
AZ909_RS06695	COG0444	Belongs to the ABC transporter superfamily
AZ909_RS06700	COG4608	Belongs to the ABC transporter superfamily
AZ909_RS06710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZ909_RS06720	COG2226	methyltransferase
AZ909_RS06725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZ909_RS06730	COG0840	transmembrane signaling receptor activity
AZ909_RS06740	COG1834	amidinotransferase
AZ909_RS06745	COG1396	sequence-specific DNA binding
AZ909_RS06765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZ909_RS06775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZ909_RS06780	COG2201	protein-glutamate methylesterase activity
AZ909_RS06815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZ909_RS06820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZ909_RS06825	COG0569	domain protein
AZ909_RS06830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZ909_RS06835	COG2081	HI0933 family
AZ909_RS06855	COG0726	polysaccharide deacetylase
AZ909_RS06870	COG1132	(ABC) transporter
AZ909_RS06880	COG3830	Belongs to the UPF0237 family
AZ909_RS06885	COG2848	UPF0210 protein
AZ909_RS06915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZ909_RS06920	COG0708	Exodeoxyribonuclease III
AZ909_RS06940	COG1234	tRNA 3'-trailer cleavage
AZ909_RS06965	COG0840	transmembrane signaling receptor activity
AZ909_RS06985	COG2207	Transcriptional regulator
AZ909_RS06985	COG4753	response regulator
AZ909_RS06990	COG2972	Histidine kinase
AZ909_RS07000	COG1175	transmembrane transport
AZ909_RS07005	COG3833	ABC-type maltose transport systems, permease component
AZ909_RS07020	COG1523	belongs to the glycosyl hydrolase 13 family
AZ909_RS07040	COG0602	queuosine metabolic process
AZ909_RS07045	COG0302	gtp cyclohydrolase
AZ909_RS07050	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZ909_RS07055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZ909_RS07070	COG1132	(ABC) transporter
AZ909_RS07075	COG1132	(ABC) transporter
AZ909_RS07100	COG1686	Belongs to the peptidase S11 family
AZ909_RS07110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZ909_RS07115	COG3874	Sporulation protein YtfJ
AZ909_RS07125	COG1686	Belongs to the peptidase S11 family
AZ909_RS07145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZ909_RS07150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZ909_RS07155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZ909_RS07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZ909_RS07170	COG1566	PFAM secretion protein HlyD family protein
AZ909_RS07175	COG1132	(ABC) transporter
AZ909_RS07205	COG1193	negative regulation of DNA recombination
AZ909_RS07220	COG0445	tRNA wobble uridine modification
AZ909_RS07230	COG0658	competence protein
AZ909_RS07230	COG2333	competence protein COMEC
AZ909_RS07240	COG3875	lactate racemase activity
AZ909_RS07245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZ909_RS07250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AZ909_RS07255	COG4208	sulfate ABC transporter
AZ909_RS07270	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
AZ909_RS07275	COG0175	sulfate reduction
AZ909_RS07280	COG2895	sulfate adenylyltransferase (ATP) activity
AZ909_RS07305	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZ909_RS07315	COG0778	Nitroreductase
AZ909_RS07325	COG2086	electron transfer activity
AZ909_RS07330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZ909_RS07335	COG1620	l-lactate permease
AZ909_RS07340	COG0277	FAD linked oxidase domain protein
AZ909_RS07345	COG1960	acyl-CoA dehydrogenase activity
AZ909_RS07400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AZ909_RS07405	COG0402	S-adenosylhomocysteine deaminase activity
AZ909_RS07445	COG0210	DNA helicase
AZ909_RS07475	COG0305	Participates in initiation and elongation during chromosome replication
AZ909_RS07495	COG3177	Filamentation induced by cAMP protein fic
AZ909_RS07500	COG1840	ABC-type Fe3 transport system, periplasmic component
AZ909_RS07505	COG3842	ATPase activity
AZ909_RS07520	COG4753	response regulator
AZ909_RS07520	COG2207	Transcriptional regulator
AZ909_RS07535	COG3328	transposase activity
AZ909_RS07540	COG0494	nUDIX hydrolase
AZ909_RS07560	COG1473	amidohydrolase
AZ909_RS07565	COG0737	Belongs to the 5'-nucleotidase family
AZ909_RS07580	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AZ909_RS07585	COG1924	4 iron, 4 sulfur cluster binding
AZ909_RS07625	COG0406	alpha-ribazole phosphatase activity
AZ909_RS07630	COG1368	sulfuric ester hydrolase activity
AZ909_RS07635	COG0488	(ABC) transporter
AZ909_RS07650	COG0561	phosphatase activity
AZ909_RS07660	COG3706	GGDEF domain
AZ909_RS07665	COG0667	Aldo Keto reductase
AZ909_RS07680	COG1725	Transcriptional regulator
AZ909_RS07685	COG1131	(ABC) transporter
AZ909_RS07720	COG0668	transmembrane transport
AZ909_RS07735	COG0531	amino acid
AZ909_RS07745	COG0561	phosphatase activity
AZ909_RS07760	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZ909_RS07770	COG3842	ATPase activity
AZ909_RS07775	COG0719	Fe-S assembly protein
AZ909_RS07810	COG0039	L-malate dehydrogenase activity
AZ909_RS07825	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZ909_RS07830	COG4605	iron ion homeostasis
AZ909_RS07835	COG4604	ABC transporter, ATP-binding protein
AZ909_RS07840	COG4607	ABC-type enterochelin transport system periplasmic component
AZ909_RS07845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZ909_RS07885	COG2208	phosphoserine phosphatase activity
AZ909_RS07890	COG2226	methyltransferase
AZ909_RS07895	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZ909_RS07900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZ909_RS07925	COG0569	domain protein
AZ909_RS07930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZ909_RS07935	COG1187	pseudouridine synthase activity
AZ909_RS07955	COG0768	penicillin binding
AZ909_RS07960	COG3292	Two component regulator propeller
AZ909_RS07960	COG2205	protein histidine kinase activity
AZ909_RS07960	COG0745	RESPONSE REGULATOR receiver
AZ909_RS07985	COG1329	Transcriptional regulator
AZ909_RS07990	COG1619	proteins homologs of microcin C7 resistance protein MccF
AZ909_RS08005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZ909_RS08010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZ909_RS08030	COG1363	Peptidase, m42
AZ909_RS08055	COG0523	cobalamin synthesis protein
AZ909_RS08065	COG0701	Predicted permease
AZ909_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
AZ909_RS08160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ909_RS08165	COG0765	amino acid transport
AZ909_RS08180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZ909_RS08190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZ909_RS08195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZ909_RS08210	COG4716	Myosin-crossreactive antigen
AZ909_RS08225	COG3835	regulator
AZ909_RS08230	COG2610	gluconate transmembrane transporter activity
AZ909_RS08235	COG1929	Belongs to the glycerate kinase type-1 family
AZ909_RS08245	COG1376	ErfK ybiS ycfS ynhG family protein
AZ909_RS08250	COG2081	HI0933 family
AZ909_RS08260	COG0539	negative regulation of cytoplasmic translation
AZ909_RS08260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZ909_RS08275	COG0523	cobalamin synthesis protein
AZ909_RS08295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZ909_RS08300	COG4974	Belongs to the 'phage' integrase family
AZ909_RS08320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AZ909_RS08330	COG1923	regulation of RNA biosynthetic process
AZ909_RS08335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZ909_RS08340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZ909_RS08360	COG2252	PERMEase
AZ909_RS08375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZ909_RS08390	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZ909_RS08405	COG0577	efflux transmembrane transporter activity
AZ909_RS08410	COG1136	(ABC) transporter
AZ909_RS08425	COG5002	protein histidine kinase activity
AZ909_RS08430	COG0534	Mate efflux family protein
AZ909_RS08435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZ909_RS08450	COG1388	LysM domain
AZ909_RS08450	COG3584	3D domain protein
AZ909_RS08455	COG4399	Belongs to the UPF0754 family
AZ909_RS08465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZ909_RS08470	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZ909_RS08475	COG1285	pathogenesis
AZ909_RS08480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZ909_RS08490	COG0488	(ABC) transporter
AZ909_RS08520	COG0133	tryptophan synthase activity
AZ909_RS08525	COG0135	phosphoribosylanthranilate isomerase activity
AZ909_RS08530	COG0134	indole-3-glycerol-phosphate synthase activity
AZ909_RS08535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZ909_RS08540	COG0512	Glutamine amidotransferase of anthranilate synthase
AZ909_RS08540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZ909_RS08615	COG1141	Ferredoxin
AZ909_RS08625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZ909_RS08645	COG1349	DNA-binding transcription factor activity
AZ909_RS08650	COG0561	phosphatase activity
AZ909_RS08670	COG0798	PFAM Bile acid sodium symporter
AZ909_RS08690	COG0640	Transcriptional regulator
AZ909_RS08700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZ909_RS08710	COG2201	protein-glutamate methylesterase activity
AZ909_RS08720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZ909_RS08730	COG0561	phosphatase activity
AZ909_RS08750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZ909_RS08755	COG1879	ABC-type sugar transport system periplasmic component
AZ909_RS08760	COG1879	ABC-type sugar transport system periplasmic component
AZ909_RS08770	COG1404	Belongs to the peptidase S8 family
AZ909_RS08785	COG0494	nUDIX hydrolase
AZ909_RS08790	COG4708	membrane
AZ909_RS08810	COG0534	Mate efflux family protein
AZ909_RS08830	COG1285	pathogenesis
AZ909_RS08850	COG1533	DNA photolyase activity
AZ909_RS08855	COG0454	-acetyltransferase
AZ909_RS08905	COG1216	Glycosyl transferase, family 2
AZ909_RS08930	COG0657	acetylesterase activity
AZ909_RS08930	COG2755	lipolytic protein G-D-S-L family
AZ909_RS08945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZ909_RS08955	COG3546	catalase activity
AZ909_RS08985	COG1199	ATP-dependent helicase activity
AZ909_RS08985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZ909_RS09025	COG0305	Participates in initiation and elongation during chromosome replication
AZ909_RS09085	COG5278	phosphoserine phosphatase activity
AZ909_RS09085	COG0840	transmembrane signaling receptor activity
AZ909_RS09095	COG1231	oxidoreductase activity
AZ909_RS09105	COG0662	Cupin 2, conserved barrel domain protein
AZ909_RS09120	COG1733	regulation of RNA biosynthetic process
AZ909_RS09135	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AZ909_RS09140	COG1253	flavin adenine dinucleotide binding
AZ909_RS09160	COG0693	protein deglycase activity
AZ909_RS09170	COG1733	regulation of RNA biosynthetic process
AZ909_RS09200	COG0494	nUDIX hydrolase
AZ909_RS09250	COG0693	protein deglycase activity
AZ909_RS09255	COG0488	(ABC) transporter
AZ909_RS09260	COG0789	Transcriptional regulator
AZ909_RS09270	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
AZ909_RS09275	COG0693	protein deglycase activity
AZ909_RS09345	COG1131	(ABC) transporter
AZ909_RS09365	COG0534	Mate efflux family protein
AZ909_RS09370	COG0390	transport system, permease component
AZ909_RS09375	COG4619	ABC transporter
AZ909_RS09405	COG1725	Transcriptional regulator
AZ909_RS09415	COG2080	2 iron, 2 sulfur cluster binding
AZ909_RS09415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZ909_RS09445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZ909_RS09445	COG3608	succinylglutamate desuccinylase aspartoacylase
AZ909_RS09450	COG3608	succinylglutamate desuccinylase aspartoacylase
AZ909_RS09450	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZ909_RS09455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZ909_RS09465	COG1396	sequence-specific DNA binding
AZ909_RS09470	COG0697	spore germination
AZ909_RS09475	COG1408	metallophosphoesterase
AZ909_RS09500	COG0395	ABC-type sugar transport system, permease component
AZ909_RS09510	COG1653	transport
AZ909_RS09515	COG0366	Alpha amylase catalytic
AZ909_RS09545	COG0277	FAD linked oxidase domain protein
AZ909_RS09550	COG2011	ABC-type metal ion transport system permease component
AZ909_RS09555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZ909_RS09565	COG0436	Aminotransferase
AZ909_RS09570	COG0626	cystathionine gamma-synthase activity
AZ909_RS09575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZ909_RS09580	COG0387	Pfam Sodium calcium exchanger
AZ909_RS09585	COG0464	growth
AZ909_RS09590	COG0406	alpha-ribazole phosphatase activity
AZ909_RS09630	COG0436	Aminotransferase
AZ909_RS09635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZ909_RS09645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZ909_RS09670	COG2801	Transposase and inactivated derivatives
AZ909_RS09675	COG0784	Response regulator, receiver
AZ909_RS09675	COG0835	chemotaxis
AZ909_RS09700	COG0745	RESPONSE REGULATOR receiver
AZ909_RS09705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZ909_RS09715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZ909_RS09735	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AZ909_RS09740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZ909_RS09825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZ909_RS09850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZ909_RS09850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZ909_RS09850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZ909_RS09855	COG1105	Belongs to the carbohydrate kinase PfkB family
AZ909_RS09860	COG1349	DNA-binding transcription factor activity
AZ909_RS09875	COG2211	Major facilitator Superfamily
AZ909_RS09890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AZ909_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
AZ909_RS09905	COG2721	sulfolactate sulfo-lyase activity
AZ909_RS09910	COG0246	Mannitol dehydrogenase
AZ909_RS09915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZ909_RS09920	COG0800	Aldolase
AZ909_RS09925	COG1904	glucuronate isomerase
AZ909_RS09930	COG1609	Transcriptional regulator
AZ909_RS09935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZ909_RS09935	COG0646	methionine synthase
AZ909_RS09945	COG1191	sigma factor activity
AZ909_RS09955	COG0484	heat shock protein binding
AZ909_RS09960	COG0514	ATP-dependent DNA helicase (RecQ)
AZ909_RS09965	COG0765	amino acid transport
AZ909_RS09970	COG0765	amino acid transport
AZ909_RS09975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ909_RS09985	COG0024	Methionine aminopeptidase
AZ909_RS10010	COG2022	thiamine diphosphate biosynthetic process
AZ909_RS10020	COG0352	thiamine-phosphate diphosphorylase activity
AZ909_RS10035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZ909_RS10040	COG0561	phosphatase activity
AZ909_RS10045	COG0697	spore germination
AZ909_RS10060	COG0534	Mate efflux family protein
AZ909_RS10075	COG0028	Belongs to the TPP enzyme family
AZ909_RS10080	COG0440	acetolactate synthase activity
AZ909_RS10085	COG3304	Inner membrane component domain
AZ909_RS10090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZ909_RS10095	COG0154	amidase activity
AZ909_RS10100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZ909_RS10105	COG0017	Asparaginyl-tRNA synthetase
AZ909_RS10120	COG0583	DNA-binding transcription factor activity
AZ909_RS10140	COG0071	Belongs to the small heat shock protein (HSP20) family
AZ909_RS10160	COG0038	chloride channel
AZ909_RS10175	COG5002	protein histidine kinase activity
AZ909_RS10205	COG3546	catalase activity
AZ909_RS10220	COG0785	Cytochrome C biogenesis protein
AZ909_RS10235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZ909_RS10240	COG3118	belongs to the thioredoxin family
AZ909_RS10245	COG0492	ferredoxin-NADP+ reductase activity
AZ909_RS10255	COG3546	catalase activity
AZ909_RS10260	COG0494	nUDIX hydrolase
AZ909_RS10280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZ909_RS10290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZ909_RS10300	COG5278	phosphoserine phosphatase activity
AZ909_RS10300	COG0840	transmembrane signaling receptor activity
AZ909_RS10315	COG4974	Belongs to the 'phage' integrase family
AZ909_RS10335	COG0411	ABC transporter
AZ909_RS10345	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZ909_RS10355	COG1011	Hydrolase
AZ909_RS10360	COG0745	RESPONSE REGULATOR receiver
AZ909_RS10390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZ909_RS10415	COG0745	RESPONSE REGULATOR receiver
AZ909_RS10420	COG0750	zinc metalloprotease
AZ909_RS10425	COG0497	DNA recombination
AZ909_RS10430	COG1438	arginine binding
AZ909_RS10435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZ909_RS10440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZ909_RS10445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZ909_RS10450	COG0142	geranyltranstransferase activity
AZ909_RS10455	COG1722	exodeoxyribonuclease VII activity
AZ909_RS10460	COG1570	exodeoxyribonuclease VII activity
AZ909_RS10470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZ909_RS10475	COG1302	Protein conserved in bacteria
AZ909_RS10515	COG3854	ATPases associated with a variety of cellular activities
AZ909_RS10590	COG1737	Transcriptional regulator
AZ909_RS10595	COG0116	Belongs to the methyltransferase superfamily
AZ909_RS10605	COG0564	pseudouridine synthase activity
AZ909_RS10625	COG1799	cell septum assembly
AZ909_RS10630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AZ909_RS10640	COG3856	small basic protein
AZ909_RS10660	COG0772	Belongs to the SEDS family
AZ909_RS10665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZ909_RS10670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZ909_RS10680	COG0768	penicillin binding
AZ909_RS10685	COG0768	penicillin binding
AZ909_RS10695	COG0275	rRNA processing
AZ909_RS10700	COG2001	Belongs to the MraZ family
AZ909_RS10725	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZ909_RS10740	COG1522	sequence-specific DNA binding
AZ909_RS10755	COG0671	phosphoesterase, PA-phosphatase related
AZ909_RS10765	COG2703	oxygen carrier activity
AZ909_RS10770	COG1966	Carbon starvation protein
AZ909_RS10785	COG0432	Pfam Uncharacterised protein family UPF0047
AZ909_RS10795	COG1012	belongs to the aldehyde dehydrogenase family
AZ909_RS10800	COG0826	peptidase U32
AZ909_RS10805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZ909_RS10820	COG0534	Mate efflux family protein
AZ909_RS10840	COG0840	transmembrane signaling receptor activity
AZ909_RS10865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZ909_RS10865	COG0425	Belongs to the sulfur carrier protein TusA family
AZ909_RS10870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZ909_RS10875	COG2966	Psort location CytoplasmicMembrane, score
AZ909_RS10905	COG0628	permease
AZ909_RS10920	COG1187	pseudouridine synthase activity
AZ909_RS10950	COG0488	(ABC) transporter
AZ909_RS10960	COG1187	pseudouridine synthase activity
AZ909_RS10965	COG0840	transmembrane signaling receptor activity
AZ909_RS10980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZ909_RS10990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZ909_RS10995	COG0628	permease
AZ909_RS11000	COG0572	uridine kinase
AZ909_RS11010	COG1307	EDD domain protein, DegV family
AZ909_RS11030	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZ909_RS11040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZ909_RS11045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZ909_RS11050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AZ909_RS11055	COG4670	ketone body catabolic process
AZ909_RS11065	COG0584	glycerophosphoryl diester phosphodiesterase
AZ909_RS11070	COG0840	transmembrane signaling receptor activity
AZ909_RS11080	COG0460	homoserine dehydrogenase
AZ909_RS11090	COG1316	TRANSCRIPTIONal
AZ909_RS11100	COG0367	asparagine synthase
AZ909_RS11105	COG4464	protein tyrosine phosphatase activity
AZ909_RS11110	COG0489	protein tyrosine kinase activity
AZ909_RS11120	COG1132	(ABC) transporter
AZ909_RS11145	COG2244	polysaccharide biosynthetic process
AZ909_RS11150	COG1442	glycosyl transferase family 8
AZ909_RS11150	COG1216	Glycosyl transferase, family 2
AZ909_RS11160	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZ909_RS11175	COG1216	Glycosyl transferase, family 2
AZ909_RS11175	COG1442	glycosyl transferase family 8
AZ909_RS11195	COG0297	glycogen (starch) synthase activity
AZ909_RS11195	COG0438	transferase activity, transferring glycosyl groups
AZ909_RS11200	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AZ909_RS11210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZ909_RS11215	COG3944	biosynthesis protein
AZ909_RS11225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZ909_RS11235	COG1811	Na channel or pump
AZ909_RS11240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZ909_RS11245	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZ909_RS11260	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZ909_RS11270	COG0303	'Molybdopterin
AZ909_RS11290	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZ909_RS11300	COG0243	molybdopterin cofactor binding
AZ909_RS11330	COG2199	diguanylate cyclase activity
AZ909_RS11330	COG2203	Gaf domain
AZ909_RS11335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZ909_RS11340	COG0124	histidyl-tRNA synthetase
AZ909_RS11345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZ909_RS11350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZ909_RS11355	COG1490	D-aminoacyl-tRNA deacylase activity
AZ909_RS11360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZ909_RS11365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZ909_RS11370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZ909_RS11370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZ909_RS11375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZ909_RS11380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZ909_RS11390	COG1862	Preprotein translocase
AZ909_RS11400	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZ909_RS11405	COG2255	four-way junction helicase activity
AZ909_RS11410	COG0632	four-way junction helicase activity
AZ909_RS11490	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AZ909_RS11510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZ909_RS11690	COG2002	toxin-antitoxin pair type II binding
AZ909_RS11695	COG1484	DNA-dependent DNA replication
AZ909_RS11720	COG0582	viral genome integration into host DNA
AZ909_RS11765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZ909_RS11775	COG0647	UMP catabolic process
AZ909_RS11780	COG0366	Alpha amylase catalytic
AZ909_RS11785	COG3833	ABC-type maltose transport systems, permease component
AZ909_RS11795	COG2182	Extracellular solute-binding protein
AZ909_RS11800	COG2207	Transcriptional regulator
AZ909_RS11800	COG1917	Cupin 2, conserved barrel domain protein
AZ909_RS11805	COG0577	efflux transmembrane transporter activity
AZ909_RS11810	COG1136	(ABC) transporter
AZ909_RS11825	COG0745	RESPONSE REGULATOR receiver
AZ909_RS11835	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AZ909_RS11840	COG1592	Rubrerythrin
AZ909_RS11840	COG1773	rubredoxin
AZ909_RS11850	COG0484	heat shock protein binding
AZ909_RS11870	COG0613	PHP domain protein
AZ909_RS11875	COG1362	aminopeptidase activity
AZ909_RS11880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZ909_RS11920	COG0646	methionine synthase
AZ909_RS11920	COG1410	methionine synthase
AZ909_RS11930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZ909_RS11970	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZ909_RS11975	COG1269	ATP hydrolysis coupled proton transport
AZ909_RS12000	COG2244	polysaccharide biosynthetic process
AZ909_RS12005	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS12010	COG1263	PTS System
AZ909_RS12010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS12010	COG2190	(PTS) system
AZ909_RS12015	COG3711	transcriptional antiterminator
AZ909_RS12025	COG0564	pseudouridine synthase activity
AZ909_RS12030	COG1473	amidohydrolase
AZ909_RS12035	COG0849	cell division
AZ909_RS12055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZ909_RS12070	COG0735	belongs to the Fur family
AZ909_RS12100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZ909_RS12105	COG1067	ATP-dependent peptidase activity
AZ909_RS12105	COG0470	DNA polymerase III
AZ909_RS12110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZ909_RS12120	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZ909_RS12135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZ909_RS12140	COG0140	phosphoribosyl-ATP diphosphatase activity
AZ909_RS12145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZ909_RS12150	COG0107	imidazoleglycerol-phosphate synthase activity
AZ909_RS12155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZ909_RS12160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZ909_RS12165	COG0131	Imidazoleglycerol-phosphate dehydratase
AZ909_RS12170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZ909_RS12175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZ909_RS12180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZ909_RS12205	COG2084	Dehydrogenase
AZ909_RS12245	COG4974	Belongs to the 'phage' integrase family
AZ909_RS12360	COG0740	serine-type endopeptidase activity
AZ909_RS12390	COG0582	viral genome integration into host DNA
AZ909_RS12470	COG1475	DNA binding
AZ909_RS12475	COG1192	Involved in chromosome partitioning
AZ909_RS12500	COG1396	sequence-specific DNA binding
AZ909_RS12525	COG0582	viral genome integration into host DNA
AZ909_RS12530	COG4492	Belongs to the UPF0735 family
AZ909_RS12535	COG0083	homoserine kinase activity
AZ909_RS12540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZ909_RS12575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZ909_RS12580	COG0113	porphobilinogen synthase activity
AZ909_RS12585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZ909_RS12585	COG1587	Uroporphyrinogen-III synthase
AZ909_RS12600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZ909_RS12610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZ909_RS12620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZ909_RS12625	COG3326	Membrane
AZ909_RS12630	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AZ909_RS12635	COG2706	6-phosphogluconolactonase activity
AZ909_RS12640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZ909_RS12650	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZ909_RS12655	COG0561	phosphatase activity
AZ909_RS12675	COG1492	cobalamin metabolic process
AZ909_RS12680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZ909_RS12725	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZ909_RS12735	COG1797	cobyrinic acid a,c-diamide synthase activity
AZ909_RS12745	COG3263	regulation of cellular component size
AZ909_RS12755	COG0840	transmembrane signaling receptor activity
AZ909_RS12770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZ909_RS12775	COG1802	Transcriptional regulator
AZ909_RS12790	COG0813	purine-nucleoside phosphorylase activity
AZ909_RS12795	COG3958	Transketolase
AZ909_RS12800	COG3959	Transketolase, thiamine diphosphate binding domain
AZ909_RS12815	COG0295	cytidine deaminase activity
AZ909_RS12820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZ909_RS12825	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AZ909_RS12840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZ909_RS12850	COG3958	Transketolase
AZ909_RS12855	COG3959	Transketolase, thiamine diphosphate binding domain
AZ909_RS12865	COG0235	Class ii aldolase
AZ909_RS12880	COG3037	sugar-specific permease SgaT UlaA
AZ909_RS12895	COG1349	DNA-binding transcription factor activity
AZ909_RS12900	COG0733	neurotransmitter:sodium symporter activity
AZ909_RS12930	COG1476	TRANSCRIPTIONal
AZ909_RS12950	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZ909_RS12955	COG4521	taurine ABC transporter
AZ909_RS12960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZ909_RS12970	COG2508	Transcriptional regulator
AZ909_RS12985	COG2200	EAL domain
AZ909_RS12990	COG0110	maltose O-acetyltransferase activity
AZ909_RS12995	COG0366	Alpha amylase catalytic
AZ909_RS13000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AZ909_RS13015	COG2059	Chromate
AZ909_RS13050	COG2207	Transcriptional regulator
AZ909_RS13065	COG2207	Transcriptional regulator
AZ909_RS13065	COG4753	response regulator
AZ909_RS13070	COG2972	Histidine kinase
AZ909_RS13075	COG3290	protein histidine kinase activity
AZ909_RS13075	COG0840	transmembrane signaling receptor activity
AZ909_RS13080	COG1874	Beta-galactosidase
AZ909_RS13100	COG1609	Transcriptional regulator
AZ909_RS13135	COG1982	Orn Lys Arg decarboxylase major
AZ909_RS13150	COG1785	Belongs to the alkaline phosphatase family
AZ909_RS13180	COG0840	transmembrane signaling receptor activity
AZ909_RS13195	COG0395	ABC-type sugar transport system, permease component
AZ909_RS13200	COG1175	transmembrane transport
AZ909_RS13215	COG2207	Transcriptional regulator
AZ909_RS13220	COG0366	Alpha amylase catalytic
AZ909_RS13225	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AZ909_RS13230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZ909_RS13235	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AZ909_RS13255	COG0366	Alpha amylase catalytic
AZ909_RS13260	COG1307	EDD domain protein, DegV family
AZ909_RS13275	COG2972	Histidine kinase
AZ909_RS13280	COG2207	Transcriptional regulator
AZ909_RS13280	COG4753	response regulator
AZ909_RS13285	COG0840	transmembrane signaling receptor activity
AZ909_RS13290	COG4214	carbohydrate transport
AZ909_RS13300	COG4213	ABC transporter substrate-binding protein
AZ909_RS13315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZ909_RS13335	COG2160	L-arabinose isomerase activity
AZ909_RS13340	COG2017	converts alpha-aldose to the beta-anomer
AZ909_RS13345	COG0561	phosphatase activity
AZ909_RS13360	COG0613	PHP domain protein
AZ909_RS13365	COG0514	ATP-dependent DNA helicase (RecQ)
AZ909_RS13375	COG0352	thiamine-phosphate diphosphorylase activity
AZ909_RS13380	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AZ909_RS13390	COG0351	phosphomethylpyrimidine kinase
AZ909_RS13405	COG2814	Major facilitator Superfamily
AZ909_RS13410	COG1378	Sugar-specific transcriptional regulator TrmB
AZ909_RS13425	COG0488	(ABC) transporter
AZ909_RS13445	COG0569	domain protein
AZ909_RS13450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZ909_RS13460	COG1122	ATPase activity
AZ909_RS13475	COG0829	nickel cation binding
AZ909_RS13485	COG0830	nickel cation binding
AZ909_RS13490	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AZ909_RS13495	COG0804	urea catabolic process
AZ909_RS13505	COG0831	urea catabolic process
AZ909_RS13520	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZ909_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
AZ909_RS13530	COG1454	alcohol dehydrogenase
AZ909_RS13535	COG1116	anion transmembrane transporter activity
AZ909_RS13540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZ909_RS13545	COG0347	Belongs to the P(II) protein family
AZ909_RS13550	COG0347	Belongs to the P(II) protein family
AZ909_RS13555	COG2508	Transcriptional regulator
AZ909_RS13565	COG0010	Belongs to the arginase family
AZ909_RS13575	COG0347	Belongs to the P(II) protein family
AZ909_RS13595	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZ909_RS13605	COG2207	Transcriptional regulator
AZ909_RS13605	COG4753	response regulator
AZ909_RS13610	COG5002	protein histidine kinase activity
AZ909_RS13610	COG2198	Histidine kinase
AZ909_RS13610	COG0784	Response regulator, receiver
AZ909_RS13615	COG4251	negative regulation of phosphorylation
AZ909_RS13620	COG1760	l-serine dehydratase
AZ909_RS13630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS13630	COG1263	PTS System
AZ909_RS13635	COG3711	transcriptional antiterminator
AZ909_RS13640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZ909_RS13645	COG2323	membrane
AZ909_RS13655	COG0137	argininosuccinate synthase activity
AZ909_RS13660	COG0165	Argininosuccinate lyase
AZ909_RS13665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZ909_RS13675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZ909_RS13680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZ909_RS13685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZ909_RS13690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZ909_RS13695	COG1268	BioY protein
AZ909_RS13710	COG1215	transferase activity, transferring glycosyl groups
AZ909_RS13725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZ909_RS13735	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AZ909_RS13740	COG2188	Transcriptional regulator
AZ909_RS13745	COG1482	cell wall glycoprotein biosynthetic process
AZ909_RS13750	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS13755	COG2755	lipolytic protein G-D-S-L family
AZ909_RS13755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZ909_RS13775	COG0840	transmembrane signaling receptor activity
AZ909_RS13780	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AZ909_RS13785	COG0395	ABC-type sugar transport system, permease component
AZ909_RS13805	COG3842	ATPase activity
AZ909_RS13815	COG4753	response regulator
AZ909_RS13815	COG2207	Transcriptional regulator
AZ909_RS13820	COG2972	Histidine kinase
AZ909_RS13855	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AZ909_RS13865	COG3458	cephalosporin-C deacetylase activity
AZ909_RS13870	COG1053	succinate dehydrogenase
AZ909_RS13875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZ909_RS13880	COG4608	Belongs to the ABC transporter superfamily
AZ909_RS13885	COG0444	Belongs to the ABC transporter superfamily
AZ909_RS13890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZ909_RS13895	COG0601	transmembrane transport
AZ909_RS13905	COG2801	Transposase and inactivated derivatives
AZ909_RS13910	COG1737	Transcriptional regulator
AZ909_RS13920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZ909_RS13930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZ909_RS13935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZ909_RS13935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZ909_RS13945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZ909_RS13950	COG2271	Major facilitator Superfamily
AZ909_RS13955	COG0662	Cupin 2, conserved barrel domain protein
AZ909_RS13955	COG2207	Transcriptional regulator
AZ909_RS13970	COG0583	DNA-binding transcription factor activity
AZ909_RS13980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZ909_RS13985	COG0077	Prephenate dehydratase
AZ909_RS13985	COG1605	Chorismate mutase
AZ909_RS13990	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZ909_RS13995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZ909_RS14000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZ909_RS14005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZ909_RS14025	COG0495	leucyl-tRNA aminoacylation
AZ909_RS14040	COG1131	(ABC) transporter
AZ909_RS14045	COG0717	Belongs to the dCTP deaminase family
AZ909_RS14080	COG2357	RelA SpoT domain protein
AZ909_RS14090	COG3290	protein histidine kinase activity
AZ909_RS14090	COG0840	transmembrane signaling receptor activity
AZ909_RS14110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZ909_RS14120	COG2199	diguanylate cyclase activity
AZ909_RS14120	COG2203	Gaf domain
AZ909_RS14125	COG0438	transferase activity, transferring glycosyl groups
AZ909_RS14130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ909_RS14135	COG3344	reverse transcriptase
AZ909_RS14140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ909_RS14145	COG5002	protein histidine kinase activity
AZ909_RS14150	COG0745	RESPONSE REGULATOR receiver
AZ909_RS14160	COG0577	efflux transmembrane transporter activity
AZ909_RS14160	COG1136	(ABC) transporter
AZ909_RS14165	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZ909_RS14170	COG1131	(ABC) transporter
AZ909_RS14175	COG1773	rubredoxin
AZ909_RS14175	COG1592	Rubrerythrin
AZ909_RS14180	COG1114	Component of the transport system for branched-chain amino acids
AZ909_RS14195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZ909_RS14205	COG0840	transmembrane signaling receptor activity
AZ909_RS14225	COG1442	glycosyl transferase family 8
AZ909_RS14225	COG1216	Glycosyl transferase, family 2
AZ909_RS14230	COG3475	LICD family
AZ909_RS14235	COG1216	Glycosyl transferase, family 2
AZ909_RS14235	COG1442	glycosyl transferase family 8
AZ909_RS14245	COG2199	diguanylate cyclase activity
AZ909_RS14245	COG2203	Gaf domain
AZ909_RS14250	COG1595	DNA-templated transcription, initiation
AZ909_RS14260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZ909_RS14260	COG1017	nitric oxide dioxygenase activity
AZ909_RS14280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZ909_RS14305	COG1349	DNA-binding transcription factor activity
AZ909_RS14310	COG0395	ABC-type sugar transport system, permease component
AZ909_RS14325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZ909_RS14335	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZ909_RS14340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZ909_RS14340	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AZ909_RS14345	COG1737	Transcriptional regulator
AZ909_RS14360	COG1486	melibiose metabolic process
AZ909_RS14370	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS14380	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZ909_RS14385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZ909_RS14405	COG0840	transmembrane signaling receptor activity
AZ909_RS14415	COG1609	Transcriptional regulator
AZ909_RS14430	COG0395	ABC-type sugar transport system, permease component
AZ909_RS14445	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS14460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZ909_RS14475	COG2188	Transcriptional regulator
AZ909_RS14485	COG0347	Belongs to the P(II) protein family
AZ909_RS14490	COG0004	ammonium transporteR
AZ909_RS14500	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS14510	COG3328	transposase activity
AZ909_RS14515	COG0840	transmembrane signaling receptor activity
AZ909_RS14520	COG0561	phosphatase activity
AZ909_RS14525	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS14530	COG1486	melibiose metabolic process
AZ909_RS14535	COG0697	spore germination
AZ909_RS14540	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AZ909_RS14545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZ909_RS14550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZ909_RS14570	COG0366	Alpha amylase catalytic
AZ909_RS14600	COG4750	Nucleotidyl transferase
AZ909_RS14625	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZ909_RS14630	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZ909_RS14630	COG2247	cell wall binding repeat
AZ909_RS14635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZ909_RS14705	COG0577	efflux transmembrane transporter activity
AZ909_RS14705	COG1136	(ABC) transporter
AZ909_RS14715	COG0840	transmembrane signaling receptor activity
AZ909_RS14725	COG0747	negative chemotaxis
AZ909_RS14730	COG0601	transmembrane transport
AZ909_RS14735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZ909_RS14740	COG0444	Belongs to the ABC transporter superfamily
AZ909_RS14745	COG4608	Belongs to the ABC transporter superfamily
AZ909_RS14760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZ909_RS14775	COG2244	polysaccharide biosynthetic process
AZ909_RS14790	COG1216	Glycosyl transferase, family 2
AZ909_RS14795	COG1216	Glycosyl transferase, family 2
AZ909_RS14795	COG1442	glycosyl transferase family 8
AZ909_RS14805	COG1215	transferase activity, transferring glycosyl groups
AZ909_RS14815	COG0438	transferase activity, transferring glycosyl groups
AZ909_RS14825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZ909_RS14835	COG0489	protein tyrosine kinase activity
AZ909_RS14840	COG3944	biosynthesis protein
AZ909_RS14845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ909_RS14850	COG3344	reverse transcriptase
AZ909_RS14855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ909_RS14945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZ909_RS14955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZ909_RS14975	COG1682	transport, permease protein
AZ909_RS14985	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZ909_RS15090	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZ909_RS15095	COG4191	Histidine kinase
AZ909_RS15095	COG2205	protein histidine kinase activity
AZ909_RS15095	COG0745	RESPONSE REGULATOR receiver
AZ909_RS15100	COG2199	diguanylate cyclase activity
AZ909_RS15100	COG2200	EAL domain
AZ909_RS15100	COG2202	Pas domain
AZ909_RS15105	COG4974	Belongs to the 'phage' integrase family
AZ909_RS15110	COG3459	Glycosyltransferase 36 associated
AZ909_RS15115	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZ909_RS15125	COG1362	aminopeptidase activity
AZ909_RS15135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZ909_RS15135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZ909_RS15140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZ909_RS15145	COG1418	mRNA catabolic process
AZ909_RS15150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZ909_RS15155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZ909_RS15160	COG3590	peptidase
AZ909_RS15165	COG1126	abc transporter atp-binding protein
AZ909_RS15170	COG0765	amino acid transport
AZ909_RS15175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ909_RS15180	COG3973	AAA domain
AZ909_RS15185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZ909_RS15210	COG0019	diaminopimelate decarboxylase activity
AZ909_RS15230	COG0840	transmembrane signaling receptor activity
AZ909_RS15240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZ909_RS15245	COG2608	mercury ion transmembrane transporter activity
AZ909_RS15255	COG1937	Protein conserved in bacteria
AZ909_RS15265	COG3279	Response regulator of the LytR AlgR family
AZ909_RS15280	COG1473	amidohydrolase
AZ909_RS15290	COG1811	Na channel or pump
AZ909_RS15295	COG4978	Transcriptional regulator
AZ909_RS15295	COG0789	Transcriptional regulator
AZ909_RS15310	COG2832	Protein of unknown function (DUF454)
AZ909_RS15320	COG1132	(ABC) transporter
AZ909_RS15325	COG4988	ABC transporter
AZ909_RS15330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZ909_RS15340	COG0745	RESPONSE REGULATOR receiver
AZ909_RS15345	COG2205	protein histidine kinase activity
AZ909_RS15350	COG0569	domain protein
AZ909_RS15355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZ909_RS15375	COG3385	transposase activity
AZ909_RS15380	COG1404	Belongs to the peptidase S8 family
AZ909_RS15390	COG2801	Transposase and inactivated derivatives
AZ909_RS15405	COG0469	pyruvate kinase activity
AZ909_RS15450	COG1481	regulation of sporulation
AZ909_RS15455	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AZ909_RS15460	COG1660	Displays ATPase and GTPase activities
AZ909_RS15465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZ909_RS15470	COG0322	excinuclease ABC activity
AZ909_RS15475	COG0768	penicillin binding
AZ909_RS15495	COG0556	nucleotide-excision repair
AZ909_RS15505	COG0793	Belongs to the peptidase S41A family
AZ909_RS15505	COG3409	Peptidoglycan-binding domain 1 protein
AZ909_RS15510	COG2177	Part of the ABC transporter FtsEX involved in
AZ909_RS15515	COG2884	Cell division ATP-binding protein ftsE
AZ909_RS15520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZ909_RS15525	COG3958	Transketolase
AZ909_RS15530	COG3959	Transketolase, thiamine diphosphate binding domain
AZ909_RS15535	COG2337	Toxic component of a toxin-antitoxin (TA) module
AZ909_RS15550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZ909_RS15550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZ909_RS15555	COG0736	holo-[acyl-carrier-protein] synthase activity
AZ909_RS15570	COG1295	ribonuclease BN
AZ909_RS15575	COG1696	Membrane protein involved in D-alanine export
AZ909_RS15600	COG1199	ATP-dependent helicase activity
AZ909_RS15610	COG2002	toxin-antitoxin pair type II binding
AZ909_RS15620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AZ909_RS15635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZ909_RS15640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZ909_RS15645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AZ909_RS15675	COG2378	regulation of single-species biofilm formation
AZ909_RS15680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZ909_RS15695	COG2357	RelA SpoT domain protein
AZ909_RS15710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZ909_RS15725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZ909_RS15735	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AZ909_RS15775	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZ909_RS15815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZ909_RS15820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZ909_RS15830	COG0297	glycogen (starch) synthase activity
AZ909_RS15855	COG2190	(PTS) system
AZ909_RS15860	COG1263	PTS System
AZ909_RS15860	COG2190	(PTS) system
AZ909_RS15860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS15865	COG3711	transcriptional antiterminator
AZ909_RS15870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZ909_RS15875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZ909_RS15880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZ909_RS15890	COG4608	Belongs to the ABC transporter superfamily
AZ909_RS15895	COG0444	Belongs to the ABC transporter superfamily
AZ909_RS15900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZ909_RS15905	COG0601	transmembrane transport
AZ909_RS15920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZ909_RS15925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZ909_RS15960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZ909_RS15970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZ909_RS15975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZ909_RS15980	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZ909_RS15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ909_RS15995	COG1126	abc transporter atp-binding protein
AZ909_RS16000	COG0765	amino acid transport
AZ909_RS16005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ909_RS16010	COG0252	asparaginase activity
AZ909_RS16020	COG1454	alcohol dehydrogenase
AZ909_RS16025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZ909_RS16050	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AZ909_RS16115	COG0590	tRNA wobble adenosine to inosine editing
AZ909_RS16120	COG4536	flavin adenine dinucleotide binding
AZ909_RS16130	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZ909_RS16165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZ909_RS16170	COG1621	beta-fructofuranosidase activity
AZ909_RS16175	COG1609	Transcriptional regulator
AZ909_RS16190	COG3620	sequence-specific DNA binding
AZ909_RS16195	COG1492	cobalamin metabolic process
AZ909_RS16205	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AZ909_RS16210	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZ909_RS16220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZ909_RS16245	COG3716	PTS system mannose fructose sorbose family IID component
AZ909_RS16250	COG3715	PTS system
AZ909_RS16255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ909_RS16260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AZ909_RS16270	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZ909_RS16285	COG3590	peptidase
AZ909_RS16290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZ909_RS16300	COG0513	Belongs to the DEAD box helicase family
AZ909_RS16310	COG1360	Flagellar Motor Protein
AZ909_RS16315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZ909_RS16320	COG2801	Transposase and inactivated derivatives
AZ909_RS16325	COG0617	tRNA 3'-terminal CCA addition
AZ909_RS16330	COG1115	amino acid carrier protein
AZ909_RS16340	COG0347	Belongs to the P(II) protein family
AZ909_RS16345	COG0004	ammonium transporteR
AZ909_RS16360	COG0659	secondary active sulfate transmembrane transporter activity
AZ909_RS16365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZ909_RS16370	COG0730	response to heat
AZ909_RS16390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AZ909_RS16395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AZ909_RS16400	COG2723	6-phospho-beta-galactosidase activity
AZ909_RS16405	COG2188	Transcriptional regulator
AZ909_RS16410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZ909_RS16420	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZ909_RS16425	COG0116	Belongs to the methyltransferase superfamily
AZ909_RS16425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZ909_RS16445	COG2824	Alkylphosphonate utilization operon protein PhnA
AZ909_RS16450	COG0306	phosphate transporter
AZ909_RS16455	COG1392	Phosphate transport regulator
AZ909_RS16470	COG0653	protein targeting
AZ909_RS16475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZ909_RS16505	COG1404	Belongs to the peptidase S8 family
AZ909_RS16515	COG1484	DNA-dependent DNA replication
AZ909_RS16560	COG2081	HI0933 family
AZ909_RS16570	COG0385	Bile acid
AZ909_RS16585	COG0281	malic enzyme
AZ909_RS16600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZ909_RS16610	COG0305	Participates in initiation and elongation during chromosome replication
AZ909_RS16615	COG1067	ATP-dependent peptidase activity
AZ909_RS16615	COG0470	DNA polymerase III
AZ909_RS16620	COG0359	binds to the 23S rRNA
AZ909_RS16625	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AZ909_RS16635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZ909_RS16645	COG0360	Binds together with S18 to 16S ribosomal RNA
AZ909_RS16655	COG0668	transmembrane transport
AZ909_RS16670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZ909_RS16680	COG2801	Transposase and inactivated derivatives
AZ909_RS16690	COG1475	DNA binding
AZ909_RS16695	COG1192	Involved in chromosome partitioning
AZ909_RS16700	COG1475	DNA binding
AZ909_RS16710	COG0445	tRNA wobble uridine modification
AZ909_RS16715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZ909_RS16720	COG1847	R3H domain protein
AZ909_RS16730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZ909_RS16735	COG0594	ribonuclease P activity
AZ909_RS16740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZ909_RS16745	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZ909_RS16750	COG0592	DNA-directed DNA polymerase activity
AZ909_RS16760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZ909_RS16770	COG0187	DNA topoisomerase II activity
AZ909_RS16775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZ909_RS16895	COG3314	Sporulation integral membrane protein YlbJ
AZ909_RS17110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZ909_RS17150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZ909_RS17295	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AZ909_RS17320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZ909_RS17405	COG0542	response to heat
AZ909_RS17670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZ909_RS17675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZ909_RS17700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZ909_RS17970	COG0058	SHG alpha-glucan phosphorylase activity
AZ909_RS18015	COG2873	o-acetylhomoserine
AZ909_RS18080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ909_RS18170	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZ909_RS18170	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AZ909_RS18370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZ909_RS18435	COG1653	transport
AZ909_RS18465	COG2222	sugar isomerase
AZ909_RS19140	COG1686	Belongs to the peptidase S11 family
AZ909_RS19260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AZ909_RS19485	COG2376	Dihydroxyacetone kinase
AZ909_RS19570	COG2199	diguanylate cyclase activity
AZ909_RS19570	COG2203	Gaf domain
AZ909_RS19585	COG0488	(ABC) transporter
AZ909_RS19650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZ909_RS20270	COG0443	Heat shock 70 kDa protein
AZ909_RS20295	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZ909_RS20335	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination