locus-tag	class	description
CCEL_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCEL_RS00010	COG0592	DNA-directed DNA polymerase activity
CCEL_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCEL_RS00030	COG0187	DNA topoisomerase II activity
CCEL_RS00035	COG1192	Involved in chromosome partitioning
CCEL_RS00040	COG1475	DNA binding
CCEL_RS00065	COG1183	phosphatidylcholine synthase activity
CCEL_RS00070	COG0546	phosphoglycolate phosphatase activity
CCEL_RS00090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CCEL_RS00090	COG0674	pyruvate-flavodoxin oxidoreductase activity
CCEL_RS00090	COG1013	pyruvate-flavodoxin oxidoreductase activity
CCEL_RS00090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCEL_RS00100	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CCEL_RS00120	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CCEL_RS00125	COG1802	Transcriptional regulator
CCEL_RS00130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCEL_RS00140	COG1247	-acetyltransferase
CCEL_RS00160	COG0736	holo-[acyl-carrier-protein] synthase activity
CCEL_RS00170	COG4717	serine-type aminopeptidase activity
CCEL_RS00175	COG0791	NLP P60 protein
CCEL_RS00180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCEL_RS00190	COG2959	enzyme of heme biosynthesis
CCEL_RS00195	COG1846	Transcriptional regulator
CCEL_RS00200	COG0242	peptide deformylase activity
CCEL_RS00230	COG4166	transmembrane transport
CCEL_RS00235	COG4608	Belongs to the ABC transporter superfamily
CCEL_RS00240	COG0444	Belongs to the ABC transporter superfamily
CCEL_RS00245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCEL_RS00250	COG0601	transmembrane transport
CCEL_RS00255	COG0840	transmembrane signaling receptor activity
CCEL_RS00265	COG1597	lipid kinase activity
CCEL_RS00270	COG0420	3'-5' exonuclease activity
CCEL_RS00275	COG0419	ATPase involved in DNA repair
CCEL_RS00280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCEL_RS00285	COG4213	ABC transporter substrate-binding protein
CCEL_RS00290	COG0360	Binds together with S18 to 16S ribosomal RNA
CCEL_RS00295	COG0629	single-stranded DNA binding
CCEL_RS00300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCEL_RS00390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCEL_RS00405	COG1605	Chorismate mutase
CCEL_RS00405	COG0077	Prephenate dehydratase
CCEL_RS00415	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CCEL_RS00420	COG0359	binds to the 23S rRNA
CCEL_RS00425	COG0305	Participates in initiation and elongation during chromosome replication
CCEL_RS00430	COG0037	tRNA processing
CCEL_RS00435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CCEL_RS00440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCEL_RS00450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCEL_RS00460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCEL_RS00465	COG1040	competence protein
CCEL_RS00485	COG1256	bacterial-type flagellum assembly
CCEL_RS00485	COG4786	Flagellar basal body rod
CCEL_RS00495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CCEL_RS00505	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CCEL_RS00510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CCEL_RS00515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CCEL_RS00525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CCEL_RS00530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CCEL_RS00550	COG1516	flagellar protein fliS
CCEL_RS00615	COG0535	radical SAM domain protein
CCEL_RS00620	COG0488	(ABC) transporter
CCEL_RS00630	COG2207	Transcriptional regulator
CCEL_RS00635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCEL_RS00640	COG0066	3-isopropylmalate dehydratase activity
CCEL_RS00645	COG0473	3-isopropylmalate dehydrogenase activity
CCEL_RS00650	COG0697	spore germination
CCEL_RS00660	COG4242	Belongs to the peptidase S51 family
CCEL_RS00665	COG0189	ligase activity
CCEL_RS00665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCEL_RS00675	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCEL_RS00675	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCEL_RS00685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CCEL_RS00695	COG0281	malic enzyme
CCEL_RS00700	COG0246	Mannitol dehydrogenase
CCEL_RS00705	COG1312	Catalyzes the dehydration of D-mannonate
CCEL_RS00715	COG0662	Cupin 2, conserved barrel domain protein
CCEL_RS00715	COG2207	Transcriptional regulator
CCEL_RS00720	COG4209	transmembrane transport
CCEL_RS00725	COG0395	ABC-type sugar transport system, permease component
CCEL_RS00730	COG1653	transport
CCEL_RS00740	COG4753	response regulator
CCEL_RS00740	COG2207	Transcriptional regulator
CCEL_RS00745	COG2972	Histidine kinase
CCEL_RS00750	COG4753	response regulator
CCEL_RS00750	COG2207	Transcriptional regulator
CCEL_RS00760	COG4209	transmembrane transport
CCEL_RS00765	COG0395	ABC-type sugar transport system, permease component
CCEL_RS00780	COG1982	Orn Lys Arg decarboxylase major
CCEL_RS00785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCEL_RS00790	COG3870	Protein conserved in bacteria
CCEL_RS00800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCEL_RS00805	COG1774	PSP1 C-terminal conserved region
CCEL_RS00815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CCEL_RS00820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CCEL_RS00825	COG2002	toxin-antitoxin pair type II binding
CCEL_RS00830	COG2715	membrane protein required for spore maturation
CCEL_RS00835	COG0700	Nucleoside recognition
CCEL_RS00845	COG0084	hydrolase, TatD family'
CCEL_RS00855	COG3584	3D domain protein
CCEL_RS00855	COG3583	domain protein
CCEL_RS00860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCEL_RS00875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CCEL_RS00880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CCEL_RS00885	COG0826	peptidase U32
CCEL_RS00895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCEL_RS00905	COG1739	Uncharacterized protein family UPF0029
CCEL_RS00910	COG0217	transcriptional regulatory protein
CCEL_RS00935	COG3708	Transcriptional regulator
CCEL_RS00935	COG2207	Transcriptional regulator
CCEL_RS00960	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CCEL_RS00980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CCEL_RS00985	COG1131	(ABC) transporter
CCEL_RS01000	COG2207	Transcriptional regulator
CCEL_RS01005	COG2972	Histidine kinase
CCEL_RS01015	COG1175	transmembrane transport
CCEL_RS01020	COG0395	ABC-type sugar transport system, permease component
CCEL_RS01025	COG1472	Belongs to the glycosyl hydrolase 3 family
CCEL_RS01035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCEL_RS01035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCEL_RS01045	COG2801	Transposase and inactivated derivatives
CCEL_RS01050	COG2252	PERMEase
CCEL_RS01055	COG3458	cephalosporin-C deacetylase activity
CCEL_RS01065	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CCEL_RS01075	COG1904	glucuronate isomerase
CCEL_RS01080	COG1331	Highly conserved protein containing a thioredoxin domain
CCEL_RS01085	COG1695	Transcriptional regulator
CCEL_RS01095	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCEL_RS01110	COG0840	transmembrane signaling receptor activity
CCEL_RS01110	COG5278	phosphoserine phosphatase activity
CCEL_RS01115	COG1725	Transcriptional regulator
CCEL_RS01120	COG1131	(ABC) transporter
CCEL_RS01165	COG4733	cellulase activity
CCEL_RS01180	COG2217	Heavy metal translocating P-type atpase
CCEL_RS01185	COG2217	Heavy metal translocating P-type atpase
CCEL_RS01215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCEL_RS01220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCEL_RS01225	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCEL_RS01230	COG0745	RESPONSE REGULATOR receiver
CCEL_RS01235	COG5002	protein histidine kinase activity
CCEL_RS01260	COG1253	flavin adenine dinucleotide binding
CCEL_RS01275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCEL_RS01280	COG0428	transporter
CCEL_RS01285	COG0009	L-threonylcarbamoyladenylate synthase
CCEL_RS01290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCEL_RS01295	COG0698	ribose 5-phosphate isomerase
CCEL_RS01300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCEL_RS01305	COG2131	deaminase
CCEL_RS01310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCEL_RS01330	COG0356	it plays a direct role in the translocation of protons across the membrane
CCEL_RS01335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCEL_RS01340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCEL_RS01345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCEL_RS01350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCEL_RS01355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCEL_RS01360	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCEL_RS01365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCEL_RS01400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCEL_RS01405	COG2385	sporulation resulting in formation of a cellular spore
CCEL_RS01415	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCEL_RS01425	COG0018	arginyl-trna synthetase
CCEL_RS01435	COG3290	protein histidine kinase activity
CCEL_RS01435	COG0840	transmembrane signaling receptor activity
CCEL_RS01450	COG0793	Belongs to the peptidase S41A family
CCEL_RS01455	COG0504	CTP synthase activity
CCEL_RS01470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCEL_RS01475	COG1131	(ABC) transporter
CCEL_RS01495	COG3949	Membrane
CCEL_RS01510	COG0129	dihydroxy-acid dehydratase activity
CCEL_RS01515	COG0028	Belongs to the TPP enzyme family
CCEL_RS01520	COG0513	Belongs to the DEAD box helicase family
CCEL_RS01525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCEL_RS01530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCEL_RS01535	COG0250	Participates in transcription elongation, termination and antitermination
CCEL_RS01540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCEL_RS01545	COG0081	regulation of translation
CCEL_RS01550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCEL_RS01560	COG0085	RNA polymerase activity
CCEL_RS01565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCEL_RS01570	COG1358	cellular component organization or biogenesis
CCEL_RS01575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCEL_RS01580	COG0049	tRNA binding
CCEL_RS01585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCEL_RS01590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCEL_RS01605	COG0426	domain, Protein
CCEL_RS01605	COG1773	rubredoxin
CCEL_RS01630	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CCEL_RS01635	COG0542	response to heat
CCEL_RS01660	COG1215	transferase activity, transferring glycosyl groups
CCEL_RS01680	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CCEL_RS01695	COG1329	Transcriptional regulator
CCEL_RS01700	COG4956	integral membrane protein (PIN domain superfamily)
CCEL_RS01705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCEL_RS01710	COG1132	(ABC) transporter
CCEL_RS01715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCEL_RS01720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCEL_RS01725	COG2340	Cysteine-rich secretory protein family
CCEL_RS01730	COG0564	pseudouridine synthase activity
CCEL_RS01735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCEL_RS01760	COG2183	response to ionizing radiation
CCEL_RS01790	COG0492	ferredoxin-NADP+ reductase activity
CCEL_RS01795	COG4191	Histidine kinase
CCEL_RS01795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCEL_RS01810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CCEL_RS01820	COG1793	dna ligase
CCEL_RS01820	COG3285	dna ligase
CCEL_RS01825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCEL_RS01845	COG1368	sulfuric ester hydrolase activity
CCEL_RS01850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCEL_RS01855	COG0210	DNA helicase
CCEL_RS01860	COG2723	6-phospho-beta-galactosidase activity
CCEL_RS01890	COG0124	histidyl-tRNA synthetase
CCEL_RS01895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCEL_RS01900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCEL_RS01905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCEL_RS01910	COG0131	Imidazoleglycerol-phosphate dehydratase
CCEL_RS01920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CCEL_RS01925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCEL_RS01930	COG0107	imidazoleglycerol-phosphate synthase activity
CCEL_RS01945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCEL_RS01950	COG0459	protein refolding
CCEL_RS01960	COG0516	GMP reductase activity
CCEL_RS01965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCEL_RS01970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCEL_RS01980	COG1366	Belongs to the anti-sigma-factor antagonist family
CCEL_RS01990	COG1191	sigma factor activity
CCEL_RS02070	COG0477	Major facilitator Superfamily
CCEL_RS02080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCEL_RS02085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCEL_RS02090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCEL_RS02100	COG3401	FG-GAP repeat protein
CCEL_RS02115	COG3546	catalase activity
CCEL_RS02140	COG1982	Orn Lys Arg decarboxylase major
CCEL_RS02150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS02165	COG3546	catalase activity
CCEL_RS02195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCEL_RS02225	COG0534	Mate efflux family protein
CCEL_RS02230	COG0052	Belongs to the universal ribosomal protein uS2 family
CCEL_RS02235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCEL_RS02240	COG0528	UMP kinase activity
CCEL_RS02245	COG0233	cytoplasmic translational termination
CCEL_RS02260	COG4589	Belongs to the CDS family
CCEL_RS02265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCEL_RS02270	COG0750	zinc metalloprotease
CCEL_RS02275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CCEL_RS02285	COG0779	Required for maturation of 30S ribosomal subunits
CCEL_RS02290	COG0195	Participates in both transcription termination and antitermination
CCEL_RS02295	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CCEL_RS02305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCEL_RS02310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCEL_RS02315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CCEL_RS02320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCEL_RS02325	COG0196	riboflavin kinase activity
CCEL_RS02330	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CCEL_RS02335	COG0298	carbon dioxide binding
CCEL_RS02340	COG0409	Hydrogenase expression formation protein
CCEL_RS02350	COG1136	(ABC) transporter
CCEL_RS02365	COG0577	efflux transmembrane transporter activity
CCEL_RS02370	COG0612	Peptidase, M16
CCEL_RS02375	COG0612	Peptidase, M16
CCEL_RS02380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCEL_RS02385	COG0772	Belongs to the SEDS family
CCEL_RS02390	COG2001	Belongs to the MraZ family
CCEL_RS02395	COG0275	rRNA processing
CCEL_RS02405	COG0768	penicillin binding
CCEL_RS02410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCEL_RS02415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCEL_RS02420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCEL_RS02425	COG0772	Belongs to the SEDS family
CCEL_RS02430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCEL_RS02440	COG2233	PERMEase
CCEL_RS02450	COG1686	Belongs to the peptidase S11 family
CCEL_RS02460	COG2766	serine protein kinase
CCEL_RS02465	COG2718	Belongs to the UPF0229 family
CCEL_RS02470	COG2719	SpoVR family
CCEL_RS02475	COG0326	Molecular chaperone. Has ATPase activity
CCEL_RS02485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCEL_RS02495	COG0840	transmembrane signaling receptor activity
CCEL_RS02505	COG0583	DNA-binding transcription factor activity
CCEL_RS02510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCEL_RS02575	COG4667	esterase of the alpha-beta hydrolase superfamily
CCEL_RS02585	COG0432	Pfam Uncharacterised protein family UPF0047
CCEL_RS02605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCEL_RS02610	COG1686	Belongs to the peptidase S11 family
CCEL_RS02615	COG0697	spore germination
CCEL_RS02660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCEL_RS02665	COG2385	sporulation resulting in formation of a cellular spore
CCEL_RS02670	COG0527	aspartate kinase activity
CCEL_RS02675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCEL_RS02680	COG0343	queuine tRNA-ribosyltransferase activity
CCEL_RS02685	COG1862	Preprotein translocase
CCEL_RS02705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCEL_RS02710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCEL_RS02725	COG0358	DNA primase activity
CCEL_RS02730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCEL_RS02745	COG2384	SAM-dependent methyltransferase
CCEL_RS02775	COG0431	NADPH-dependent FMN reductase
CCEL_RS02780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCEL_RS02790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCEL_RS02815	COG1136	(ABC) transporter
CCEL_RS02825	COG0745	RESPONSE REGULATOR receiver
CCEL_RS02830	COG2205	protein histidine kinase activity
CCEL_RS02830	COG2202	Pas domain
CCEL_RS02855	COG0006	proline dipeptidase activity
CCEL_RS02925	COG1702	phosphate starvation-inducible protein PhoH
CCEL_RS02930	COG1480	7TM receptor with intracellular HD hydrolase
CCEL_RS02935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCEL_RS02940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCEL_RS02945	COG0295	cytidine deaminase activity
CCEL_RS02950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCEL_RS02955	COG1381	Involved in DNA repair and RecF pathway recombination
CCEL_RS02960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCEL_RS02965	COG1132	(ABC) transporter
CCEL_RS02970	COG1132	(ABC) transporter
CCEL_RS02985	COG4224	UPF0291 protein
CCEL_RS02990	COG0835	chemotaxis
CCEL_RS03000	COG0012	GTP binding
CCEL_RS03015	COG0564	pseudouridine synthase activity
CCEL_RS03020	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CCEL_RS03030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCEL_RS03035	COG1799	cell septum assembly
CCEL_RS03045	COG2302	S4 RNA-binding domain
CCEL_RS03050	COG3599	regulation of cell shape
CCEL_RS03070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CCEL_RS03075	COG1418	mRNA catabolic process
CCEL_RS03080	COG1692	metallophosphoesterase
CCEL_RS03085	COG1496	oxidoreductase activity
CCEL_RS03095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CCEL_RS03100	COG0564	pseudouridine synthase activity
CCEL_RS03105	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CCEL_RS03110	COG0540	Belongs to the ATCase OTCase family
CCEL_RS03115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCEL_RS03120	COG0284	orotidine-5'-phosphate decarboxylase activity
CCEL_RS03130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCEL_RS03135	COG0543	2 iron, 2 sulfur cluster binding
CCEL_RS03140	COG0167	dihydroorotate dehydrogenase activity
CCEL_RS03145	COG0588	phosphoglycerate mutase activity
CCEL_RS03160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCEL_RS03170	COG1533	DNA photolyase activity
CCEL_RS03180	COG5001	Diguanylate cyclase
CCEL_RS03180	COG3300	MHYT domain
CCEL_RS03185	COG1342	Belongs to the UPF0251 family
CCEL_RS03200	COG0583	DNA-binding transcription factor activity
CCEL_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS03265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCEL_RS03270	COG3858	chitin binding
CCEL_RS03275	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CCEL_RS03280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CCEL_RS03285	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CCEL_RS03300	COG4733	cellulase activity
CCEL_RS03330	COG0697	spore germination
CCEL_RS03355	COG1247	-acetyltransferase
CCEL_RS03365	COG0210	DNA helicase
CCEL_RS03370	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CCEL_RS03375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCEL_RS03385	COG0586	Pfam SNARE associated Golgi protein
CCEL_RS03405	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CCEL_RS03430	COG1546	Belongs to the CinA family
CCEL_RS03430	COG1058	Belongs to the CinA family
CCEL_RS03435	COG0728	peptidoglycan biosynthetic process
CCEL_RS03440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCEL_RS03450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCEL_RS03455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCEL_RS03460	COG2030	dehydratase
CCEL_RS03465	COG0416	fatty acid biosynthetic process
CCEL_RS03470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCEL_RS03475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CCEL_RS03480	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS03485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS03490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCEL_RS03495	COG0571	ribonuclease III activity
CCEL_RS03505	COG2359	stage V sporulation protein S
CCEL_RS03510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCEL_RS03535	COG0667	Aldo Keto reductase
CCEL_RS03545	COG0552	protein localization to endoplasmic reticulum
CCEL_RS03550	COG1615	UPF0182 protein
CCEL_RS03555	COG0531	amino acid
CCEL_RS03565	COG4443	Transcriptional Coactivator p15 (PC4)
CCEL_RS03580	COG1368	sulfuric ester hydrolase activity
CCEL_RS03600	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CCEL_RS03605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCEL_RS03610	COG0228	four-way junction DNA binding
CCEL_RS03615	COG1837	Belongs to the UPF0109 family
CCEL_RS03620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCEL_RS03625	COG0336	Belongs to the RNA methyltransferase TrmD family
CCEL_RS03630	COG0335	large ribosomal subunit rRNA binding
CCEL_RS03645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCEL_RS03655	COG2257	FlhB HrpN YscU SpaS Family
CCEL_RS03660	COG0792	nuclease activity
CCEL_RS03670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCEL_RS03675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCEL_RS03680	COG2188	Transcriptional regulator
CCEL_RS03690	COG0586	Pfam SNARE associated Golgi protein
CCEL_RS03700	COG5297	Belongs to the glycosyl hydrolase family 6
CCEL_RS03705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CCEL_RS03710	COG4733	cellulase activity
CCEL_RS03715	COG2273	Hydrolase Family 16
CCEL_RS03715	COG5297	Belongs to the glycosyl hydrolase family 6
CCEL_RS03740	COG4733	cellulase activity
CCEL_RS03745	COG3401	FG-GAP repeat protein
CCEL_RS03750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS03755	COG0583	DNA-binding transcription factor activity
CCEL_RS03765	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCEL_RS03770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCEL_RS03780	COG2217	Heavy metal translocating P-type atpase
CCEL_RS03795	COG1151	hydroxylamine reductase activity
CCEL_RS03805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCEL_RS03810	COG4124	Belongs to the glycosyl hydrolase 26 family
CCEL_RS03825	COG3291	Pkd domain containing protein
CCEL_RS03855	COG0051	transcription antitermination factor activity, RNA binding
CCEL_RS03860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCEL_RS03865	COG0088	Forms part of the polypeptide exit tunnel
CCEL_RS03870	COG0089	rRNA binding
CCEL_RS03875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCEL_RS03880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCEL_RS03885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCEL_RS03890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCEL_RS03895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCEL_RS03900	COG0255	Belongs to the universal ribosomal protein uL29 family
CCEL_RS03905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCEL_RS03910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCEL_RS03915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCEL_RS03920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCEL_RS03925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCEL_RS03930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCEL_RS03935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCEL_RS03940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCEL_RS03945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCEL_RS03950	COG1841	ribosomal large subunit assembly
CCEL_RS03955	COG0200	Binds to the 23S rRNA
CCEL_RS03960	COG0201	protein transport
CCEL_RS03965	COG0563	adenylate kinase activity
CCEL_RS03980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCEL_RS03985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCEL_RS03990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCEL_RS04000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCEL_RS04005	COG0202	RNA polymerase activity
CCEL_RS04010	COG0203	ribosomal protein L17
CCEL_RS04015	COG1122	ATPase activity
CCEL_RS04020	COG2813	Specifically methylates the guanine in position
CCEL_RS04025	COG1122	ATPase activity
CCEL_RS04030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CCEL_RS04035	COG0101	tRNA pseudouridine synthase activity
CCEL_RS04040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCEL_RS04045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCEL_RS04050	COG1914	H( )-stimulated, divalent metal cation uptake system
CCEL_RS04060	COG1228	amidohydrolase
CCEL_RS04065	COG0802	atpase or kinase
CCEL_RS04070	COG1214	PFAM Peptidase M22, glycoprotease
CCEL_RS04075	COG0456	acetyltransferase
CCEL_RS04080	COG1067	ATP-dependent peptidase activity
CCEL_RS04085	COG1595	DNA-templated transcription, initiation
CCEL_RS04105	COG0322	excinuclease ABC activity
CCEL_RS04115	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCEL_RS04120	COG0740	serine-type endopeptidase activity
CCEL_RS04125	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCEL_RS04130	COG1067	ATP-dependent peptidase activity
CCEL_RS04130	COG0470	DNA polymerase III
CCEL_RS04140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCEL_RS04145	COG0741	lytic transglycosylase activity
CCEL_RS04160	COG0613	PHP domain protein
CCEL_RS04165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCEL_RS04265	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS04270	COG1917	Cupin 2, conserved barrel domain protein
CCEL_RS04270	COG2207	Transcriptional regulator
CCEL_RS04325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCEL_RS04330	COG3321	synthase
CCEL_RS04335	COG2070	2-Nitropropane dioxygenase
CCEL_RS04335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CCEL_RS04340	COG1136	(ABC) transporter
CCEL_RS04340	COG0577	efflux transmembrane transporter activity
CCEL_RS04360	COG3321	synthase
CCEL_RS04360	COG4221	oxidoreductase activity
CCEL_RS04360	COG0300	oxidoreductase activity
CCEL_RS04360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS04380	COG4221	oxidoreductase activity
CCEL_RS04380	COG3321	synthase
CCEL_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS04380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS04385	COG4221	oxidoreductase activity
CCEL_RS04385	COG3321	synthase
CCEL_RS04385	COG0300	oxidoreductase activity
CCEL_RS04385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS04400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCEL_RS04410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCEL_RS04420	COG2267	carboxylic ester hydrolase activity
CCEL_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS04435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCEL_RS04440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCEL_RS04460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCEL_RS04465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCEL_RS04470	COG1116	anion transmembrane transporter activity
CCEL_RS04485	COG0726	polysaccharide deacetylase
CCEL_RS04495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCEL_RS04500	COG0765	amino acid transport
CCEL_RS04505	COG1126	abc transporter atp-binding protein
CCEL_RS04510	COG1396	sequence-specific DNA binding
CCEL_RS04515	COG3842	ATPase activity
CCEL_RS04520	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCEL_RS04525	COG1177	transmembrane transport
CCEL_RS04530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCEL_RS04550	COG1022	Amp-dependent synthetase and ligase
CCEL_RS04555	COG0534	Mate efflux family protein
CCEL_RS04560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCEL_RS04565	COG2733	membrane
CCEL_RS04580	COG1773	rubredoxin
CCEL_RS04580	COG1592	Rubrerythrin
CCEL_RS04595	COG2801	Transposase and inactivated derivatives
CCEL_RS04610	COG2814	Major facilitator Superfamily
CCEL_RS04615	COG0402	S-adenosylhomocysteine deaminase activity
CCEL_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS04625	COG0745	RESPONSE REGULATOR receiver
CCEL_RS04640	COG0745	RESPONSE REGULATOR receiver
CCEL_RS04660	COG0551	DNA topoisomerase type I activity
CCEL_RS04660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCEL_RS04665	COG1606	tRNA processing
CCEL_RS04670	COG1959	2 iron, 2 sulfur cluster binding
CCEL_RS04705	COG0439	Biotin carboxylase
CCEL_RS04710	COG0511	ligase activity, forming carbon-carbon bonds
CCEL_RS04715	COG0439	Biotin carboxylase
CCEL_RS04720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCEL_RS04725	COG0825	malonyl-CoA metabolic process
CCEL_RS04735	COG1233	COG1233 Phytoene dehydrogenase and related
CCEL_RS04740	COG1082	Xylose isomerase domain protein TIM barrel
CCEL_RS04745	COG2081	HI0933 family
CCEL_RS04750	COG0445	tRNA wobble uridine modification
CCEL_RS04760	COG2972	Histidine kinase
CCEL_RS04765	COG4209	transmembrane transport
CCEL_RS04770	COG0395	ABC-type sugar transport system, permease component
CCEL_RS04775	COG2182	Extracellular solute-binding protein
CCEL_RS04780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCEL_RS04785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCEL_RS04790	COG0445	tRNA wobble uridine modification
CCEL_RS04795	COG1063	alcohol dehydrogenase
CCEL_RS04800	COG1063	alcohol dehydrogenase
CCEL_RS04820	COG1396	sequence-specific DNA binding
CCEL_RS04845	COG1201	RNA secondary structure unwinding
CCEL_RS04855	COG1131	(ABC) transporter
CCEL_RS04870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCEL_RS04875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCEL_RS04880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCEL_RS04885	COG1819	glycosyl
CCEL_RS04890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCEL_RS04920	COG3433	isochorismatase activity
CCEL_RS04920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS04920	COG2226	methyltransferase
CCEL_RS04920	COG2226	methyltransferase
CCEL_RS04920	COG3433	isochorismatase activity
CCEL_RS04920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS04930	COG0076	glutamate decarboxylase activity
CCEL_RS04950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS04955	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCEL_RS04975	COG1917	Cupin 2, conserved barrel domain protein
CCEL_RS04975	COG4977	sequence-specific DNA binding
CCEL_RS04990	COG3420	alginic acid biosynthetic process
CCEL_RS04995	COG2972	Histidine kinase
CCEL_RS04995	COG0745	RESPONSE REGULATOR receiver
CCEL_RS05000	COG2207	Transcriptional regulator
CCEL_RS05000	COG4753	response regulator
CCEL_RS05020	COG1175	transmembrane transport
CCEL_RS05025	COG0395	ABC-type sugar transport system, permease component
CCEL_RS05035	COG1486	melibiose metabolic process
CCEL_RS05040	COG2207	Transcriptional regulator
CCEL_RS05040	COG1917	Cupin 2, conserved barrel domain protein
CCEL_RS05045	COG1501	Belongs to the glycosyl hydrolase 31 family
CCEL_RS05055	COG1070	Carbohydrate kinase
CCEL_RS05060	COG1063	alcohol dehydrogenase
CCEL_RS05070	COG0656	L-ascorbic acid biosynthetic process
CCEL_RS05075	COG4154	Belongs to the RbsD FucU family
CCEL_RS05090	COG3250	beta-galactosidase activity
CCEL_RS05095	COG4209	transmembrane transport
CCEL_RS05100	COG0395	ABC-type sugar transport system, permease component
CCEL_RS05140	COG1473	amidohydrolase
CCEL_RS05145	COG2860	membrane
CCEL_RS05170	COG1063	alcohol dehydrogenase
CCEL_RS05175	COG1063	alcohol dehydrogenase
CCEL_RS05180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCEL_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS05195	COG2390	Transcriptional regulator
CCEL_RS05200	COG0346	lactoylglutathione lyase activity
CCEL_RS05215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCEL_RS05235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCEL_RS05240	COG0561	phosphatase activity
CCEL_RS05245	COG2226	methyltransferase
CCEL_RS05250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCEL_RS05255	COG1032	radical SAM domain protein
CCEL_RS05275	COG3973	AAA domain
CCEL_RS05285	COG0500	methyltransferase
CCEL_RS05310	COG0492	ferredoxin-NADP+ reductase activity
CCEL_RS05315	COG0492	ferredoxin-NADP+ reductase activity
CCEL_RS05320	COG1309	transcriptional regulator
CCEL_RS05325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS05345	COG0640	Transcriptional regulator
CCEL_RS05350	COG0701	Predicted permease
CCEL_RS05380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CCEL_RS05385	COG0662	Cupin 2, conserved barrel domain protein
CCEL_RS05390	COG2188	Transcriptional regulator
CCEL_RS05400	COG3845	ABC transporter
CCEL_RS05405	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS05410	COG1079	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS05425	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CCEL_RS05475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CCEL_RS05480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CCEL_RS05485	COG0519	Catalyzes the synthesis of GMP from XMP
CCEL_RS05510	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS05525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCEL_RS05565	COG1063	alcohol dehydrogenase
CCEL_RS05570	COG3858	chitin binding
CCEL_RS05570	COG1388	LysM domain
CCEL_RS05575	COG1252	NADH dehydrogenase
CCEL_RS05610	COG1166	arginine decarboxylase activity
CCEL_RS05625	COG2323	membrane
CCEL_RS05635	COG2323	membrane
CCEL_RS05680	COG1696	Membrane protein involved in D-alanine export
CCEL_RS05705	COG2972	Histidine kinase
CCEL_RS05710	COG2207	Transcriptional regulator
CCEL_RS05710	COG4753	response regulator
CCEL_RS05715	COG1472	Belongs to the glycosyl hydrolase 3 family
CCEL_RS05720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCEL_RS05740	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCEL_RS05750	COG1968	undecaprenyl-diphosphatase activity
CCEL_RS05755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCEL_RS05770	COG1136	(ABC) transporter
CCEL_RS05775	COG0577	efflux transmembrane transporter activity
CCEL_RS05775	COG1136	(ABC) transporter
CCEL_RS05780	COG0745	RESPONSE REGULATOR receiver
CCEL_RS05785	COG5002	protein histidine kinase activity
CCEL_RS05795	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CCEL_RS05800	COG0745	RESPONSE REGULATOR receiver
CCEL_RS05805	COG2205	protein histidine kinase activity
CCEL_RS05830	COG2801	Transposase and inactivated derivatives
CCEL_RS05835	COG1013	pyruvate-flavodoxin oxidoreductase activity
CCEL_RS05835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CCEL_RS05835	COG0674	pyruvate-flavodoxin oxidoreductase activity
CCEL_RS05835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCEL_RS05850	COG3279	Response regulator of the LytR AlgR family
CCEL_RS05860	COG0586	Pfam SNARE associated Golgi protein
CCEL_RS05870	COG0697	spore germination
CCEL_RS05875	COG1917	Cupin 2, conserved barrel domain protein
CCEL_RS05875	COG4977	sequence-specific DNA binding
CCEL_RS05880	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS05885	COG0737	Belongs to the 5'-nucleotidase family
CCEL_RS05900	COG4152	abc transporter atp-binding protein
CCEL_RS05905	COG1668	transmembrane transport
CCEL_RS05910	COG1482	cell wall glycoprotein biosynthetic process
CCEL_RS05925	COG0310	cobalt ion transport
CCEL_RS05935	COG1122	ATPase activity
CCEL_RS05955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CCEL_RS05960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCEL_RS05965	COG1846	Transcriptional regulator
CCEL_RS05975	COG1132	(ABC) transporter
CCEL_RS05995	COG0628	permease
CCEL_RS06025	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CCEL_RS06035	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CCEL_RS06040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCEL_RS06045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCEL_RS06055	COG4447	cellulose binding
CCEL_RS06065	COG2801	Transposase and inactivated derivatives
CCEL_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS06095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCEL_RS06110	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CCEL_RS06130	COG1879	ABC-type sugar transport system periplasmic component
CCEL_RS06135	COG1129	ABC transporter
CCEL_RS06140	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS06145	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS06150	COG2972	Histidine kinase
CCEL_RS06155	COG4753	response regulator
CCEL_RS06155	COG2207	Transcriptional regulator
CCEL_RS06160	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06165	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS06170	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06175	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06175	COG2382	esterase
CCEL_RS06175	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS06180	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06185	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06185	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS06185	COG2382	esterase
CCEL_RS06190	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS06200	COG3345	alpha-galactosidase
CCEL_RS06205	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06210	COG3250	beta-galactosidase activity
CCEL_RS06215	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS06215	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06215	COG2382	esterase
CCEL_RS06220	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06225	COG5520	Belongs to the glycosyl hydrolase 30 family
CCEL_RS06240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CCEL_RS06245	COG4677	pectinesterase activity
CCEL_RS06260	COG4733	cellulase activity
CCEL_RS06265	COG2972	Histidine kinase
CCEL_RS06270	COG4753	response regulator
CCEL_RS06270	COG2207	Transcriptional regulator
CCEL_RS06275	COG1653	transport
CCEL_RS06280	COG4209	transmembrane transport
CCEL_RS06285	COG0395	ABC-type sugar transport system, permease component
CCEL_RS06290	COG3534	alpha-L-arabinofuranosidase
CCEL_RS06300	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS06330	COG2186	Transcriptional regulator
CCEL_RS06335	COG0129	dihydroxy-acid dehydratase activity
CCEL_RS06340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCEL_RS06350	COG0310	cobalt ion transport
CCEL_RS06365	COG1122	ATPase activity
CCEL_RS06370	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CCEL_RS06405	COG0181	hydroxymethylbilane synthase activity
CCEL_RS06420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCEL_RS06435	COG1797	cobyrinic acid a,c-diamide synthase activity
CCEL_RS06440	COG1492	cobalamin metabolic process
CCEL_RS06455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCEL_RS06465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CCEL_RS06480	COG3279	Response regulator of the LytR AlgR family
CCEL_RS06560	COG0463	Glycosyl transferase, family 2
CCEL_RS06570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCEL_RS06575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CCEL_RS06580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCEL_RS06585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCEL_RS06590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCEL_RS06595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCEL_RS06630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCEL_RS06640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCEL_RS06645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCEL_RS06650	COG1534	Rna-binding protein
CCEL_RS06665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCEL_RS06670	COG0302	gtp cyclohydrolase
CCEL_RS06675	COG1418	mRNA catabolic process
CCEL_RS06680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCEL_RS06685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCEL_RS06685	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CCEL_RS06690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCEL_RS06695	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CCEL_RS06700	COG0297	glycogen (starch) synthase activity
CCEL_RS06750	COG0165	Argininosuccinate lyase
CCEL_RS06755	COG0137	argininosuccinate synthase activity
CCEL_RS06760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CCEL_RS06765	COG0632	four-way junction helicase activity
CCEL_RS06770	COG2255	four-way junction helicase activity
CCEL_RS06775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCEL_RS06780	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCEL_RS06780	COG2247	cell wall binding repeat
CCEL_RS06785	COG5401	PFAM Sporulation and spore germination
CCEL_RS06790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CCEL_RS06795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCEL_RS06825	COG3773	Cell wall hydrolase
CCEL_RS06855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CCEL_RS06860	COG1713	HD superfamily hydrolase involved in NAD metabolism
CCEL_RS06870	COG0799	negative regulation of ribosome biogenesis
CCEL_RS06875	COG0488	(ABC) transporter
CCEL_RS06890	COG1686	Belongs to the peptidase S11 family
CCEL_RS06895	COG1596	polysaccharide export
CCEL_RS06895	COG1555	photosystem II stabilization
CCEL_RS06900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCEL_RS06930	COG2801	Transposase and inactivated derivatives
CCEL_RS06950	COG2268	Band 7 protein
CCEL_RS06955	COG0840	transmembrane signaling receptor activity
CCEL_RS06960	COG0488	(ABC) transporter
CCEL_RS06965	COG1132	(ABC) transporter
CCEL_RS06970	COG1132	(ABC) transporter
CCEL_RS06995	COG1803	Methylglyoxal synthase
CCEL_RS07015	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CCEL_RS07030	COG0187	DNA topoisomerase II activity
CCEL_RS07055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCEL_RS07070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCEL_RS07080	COG3845	ABC transporter
CCEL_RS07085	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS07090	COG1079	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS07100	COG1971	Probably functions as a manganese efflux pump
CCEL_RS07105	COG0556	nucleotide-excision repair
CCEL_RS07115	COG1346	cytolysis
CCEL_RS07125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCEL_RS07130	COG2217	Heavy metal translocating P-type atpase
CCEL_RS07145	COG0477	Major facilitator Superfamily
CCEL_RS07150	COG2314	TM2 domain
CCEL_RS07165	COG1151	hydroxylamine reductase activity
CCEL_RS07175	COG2340	Cysteine-rich secretory protein family
CCEL_RS07185	COG2207	Transcriptional regulator
CCEL_RS07185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCEL_RS07190	COG1132	(ABC) transporter
CCEL_RS07195	COG1132	(ABC) transporter
CCEL_RS07215	COG1193	negative regulation of DNA recombination
CCEL_RS07230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCEL_RS07245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCEL_RS07250	COG1609	Transcriptional regulator
CCEL_RS07255	COG3459	Glycosyltransferase 36 associated
CCEL_RS07275	COG0072	phenylalanine-tRNA ligase activity
CCEL_RS07285	COG0166	Belongs to the GPI family
CCEL_RS07295	COG0285	dihydrofolate synthase activity
CCEL_RS07305	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCEL_RS07315	COG4492	Belongs to the UPF0735 family
CCEL_RS07320	COG0460	homoserine dehydrogenase
CCEL_RS07335	COG4496	protein, YerC YecD
CCEL_RS07345	COG0653	protein targeting
CCEL_RS07385	COG0484	heat shock protein binding
CCEL_RS07405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCEL_RS07410	COG1193	negative regulation of DNA recombination
CCEL_RS07415	COG1217	gtp-binding protein TYPA
CCEL_RS07420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCEL_RS07425	COG4122	O-methyltransferase activity
CCEL_RS07430	COG0826	peptidase U32
CCEL_RS07475	COG1518	maintenance of DNA repeat elements
CCEL_RS07480	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CCEL_RS07495	COG0768	penicillin binding
CCEL_RS07520	COG4447	cellulose binding
CCEL_RS07520	COG5297	Belongs to the glycosyl hydrolase family 6
CCEL_RS07555	COG0464	growth
CCEL_RS07685	COG1477	protein flavinylation
CCEL_RS07705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCEL_RS07710	COG0242	peptide deformylase activity
CCEL_RS07715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCEL_RS07725	COG2738	Putative neutral zinc metallopeptidase
CCEL_RS07730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCEL_RS07730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCEL_RS07735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCEL_RS07740	COG0631	protein serine/threonine phosphatase activity
CCEL_RS07745	COG2815	serine threonine protein kinase
CCEL_RS07745	COG0515	serine threonine protein kinase
CCEL_RS07750	COG1162	GTPase activity
CCEL_RS07755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCEL_RS07805	COG5002	protein histidine kinase activity
CCEL_RS07810	COG0745	RESPONSE REGULATOR receiver
CCEL_RS07815	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS07820	COG1917	Cupin 2, conserved barrel domain protein
CCEL_RS07820	COG2207	Transcriptional regulator
CCEL_RS07835	COG4124	Belongs to the glycosyl hydrolase 26 family
CCEL_RS07855	COG0671	phosphoesterase, PA-phosphatase related
CCEL_RS07865	COG2918	glutathione biosynthetic process
CCEL_RS07940	COG2801	Transposase and inactivated derivatives
CCEL_RS07995	COG2801	Transposase and inactivated derivatives
CCEL_RS08050	COG2801	Transposase and inactivated derivatives
CCEL_RS08065	COG3345	alpha-galactosidase
CCEL_RS08085	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCEL_RS08100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCEL_RS08105	COG1763	Mo-molybdopterin cofactor biosynthetic process
CCEL_RS08110	COG0303	'Molybdopterin
CCEL_RS08115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CCEL_RS08120	COG2086	electron transfer activity
CCEL_RS08130	COG1433	Dinitrogenase iron-molybdenum cofactor
CCEL_RS08130	COG0535	radical SAM domain protein
CCEL_RS08135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCEL_RS08140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCEL_RS08170	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CCEL_RS08170	COG1605	Chorismate mutase
CCEL_RS08185	COG0066	3-isopropylmalate dehydratase activity
CCEL_RS08190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCEL_RS08200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCEL_RS08205	COG1960	acyl-CoA dehydrogenase activity
CCEL_RS08230	COG0765	amino acid transport
CCEL_RS08250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCEL_RS08265	COG1461	Dihydroxyacetone kinase
CCEL_RS08270	COG2376	Dihydroxyacetone kinase
CCEL_RS08275	COG0698	ribose 5-phosphate isomerase
CCEL_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS08285	COG1879	ABC-type sugar transport system periplasmic component
CCEL_RS08290	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCEL_RS08295	COG1129	ABC transporter
CCEL_RS08300	COG2207	Transcriptional regulator
CCEL_RS08300	COG4753	response regulator
CCEL_RS08305	COG2972	Histidine kinase
CCEL_RS08310	COG0861	Integral membrane protein TerC family
CCEL_RS08315	COG4447	cellulose binding
CCEL_RS08315	COG4733	cellulase activity
CCEL_RS08320	COG0730	response to heat
CCEL_RS08345	COG4974	Belongs to the 'phage' integrase family
CCEL_RS08355	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS08365	COG0745	RESPONSE REGULATOR receiver
CCEL_RS08370	COG5002	protein histidine kinase activity
CCEL_RS08375	COG0785	Cytochrome C biogenesis protein
CCEL_RS08380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCEL_RS08390	COG1846	Transcriptional regulator
CCEL_RS08390	COG1940	carbohydrate kinase activity
CCEL_RS08395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCEL_RS08425	COG3250	beta-galactosidase activity
CCEL_RS08435	COG0800	Aldolase
CCEL_RS08440	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS08445	COG1312	Catalyzes the dehydration of D-mannonate
CCEL_RS08450	COG2211	Major facilitator Superfamily
CCEL_RS08455	COG1904	glucuronate isomerase
CCEL_RS08465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCEL_RS08475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCEL_RS08490	COG0301	tRNA thio-modification
CCEL_RS08495	COG1104	cysteine desulfurase activity
CCEL_RS08505	COG3260	NADH ubiquinone oxidoreductase 20
CCEL_RS08510	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CCEL_RS08510	COG3261	NADH dehydrogenase
CCEL_RS08515	COG0651	ATP synthesis coupled electron transport
CCEL_RS08530	COG0651	ATP synthesis coupled electron transport
CCEL_RS08540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCEL_RS08545	COG1923	regulation of RNA biosynthetic process
CCEL_RS08550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCEL_RS08555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCEL_RS08560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCEL_RS08570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCEL_RS08590	COG0740	serine-type endopeptidase activity
CCEL_RS08595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCEL_RS08605	COG0612	Peptidase, M16
CCEL_RS08610	COG1185	polyribonucleotide nucleotidyltransferase activity
CCEL_RS08615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCEL_RS08620	COG0714	Associated with various cellular activities
CCEL_RS08630	COG1305	Transglutaminase-like
CCEL_RS08640	COG2205	protein histidine kinase activity
CCEL_RS08660	COG1316	TRANSCRIPTIONal
CCEL_RS08670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCEL_RS08685	COG2848	UPF0210 protein
CCEL_RS08690	COG3830	Belongs to the UPF0237 family
CCEL_RS08705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCEL_RS08715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CCEL_RS08720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CCEL_RS08720	COG0539	negative regulation of cytoplasmic translation
CCEL_RS08725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCEL_RS08745	COG2081	HI0933 family
CCEL_RS08765	COG0511	ligase activity, forming carbon-carbon bonds
CCEL_RS08770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCEL_RS08775	COG1191	sigma factor activity
CCEL_RS08780	COG5183	chlorophyll binding
CCEL_RS08780	COG2133	pyrroloquinoline quinone binding
CCEL_RS08785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CCEL_RS08795	COG1187	pseudouridine synthase activity
CCEL_RS08800	COG3874	Sporulation protein YtfJ
CCEL_RS08810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCEL_RS08815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCEL_RS08820	COG1994	Peptidase M50
CCEL_RS08825	COG1686	Belongs to the peptidase S11 family
CCEL_RS08830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CCEL_RS08835	COG4974	Belongs to the 'phage' integrase family
CCEL_RS08840	COG1300	Membrane
CCEL_RS08850	COG0328	RNA-DNA hybrid ribonuclease activity
CCEL_RS08855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCEL_RS08865	COG1620	l-lactate permease
CCEL_RS08875	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CCEL_RS08890	COG1363	Peptidase, m42
CCEL_RS08905	COG4608	Belongs to the ABC transporter superfamily
CCEL_RS08910	COG0444	Belongs to the ABC transporter superfamily
CCEL_RS08915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCEL_RS08920	COG0601	transmembrane transport
CCEL_RS08935	COG1132	(ABC) transporter
CCEL_RS08940	COG1132	(ABC) transporter
CCEL_RS08945	COG1323	Belongs to the UPF0348 family
CCEL_RS08950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CCEL_RS08955	COG0438	transferase activity, transferring glycosyl groups
CCEL_RS08970	COG1074	ATP-dependent DNA helicase activity
CCEL_RS08975	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CCEL_RS09000	COG0517	IMP dehydrogenase activity
CCEL_RS09005	COG0789	Transcriptional regulator
CCEL_RS09015	COG1376	ErfK ybiS ycfS ynhG family protein
CCEL_RS09020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCEL_RS09025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CCEL_RS09030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CCEL_RS09040	COG0423	glycine-tRNA ligase activity
CCEL_RS09045	COG1758	RNA polymerase activity
CCEL_RS09050	COG0194	GDP metabolic process
CCEL_RS09055	COG2052	Domain of unknown function (DUF370)
CCEL_RS09060	COG1561	YicC-like family, N-terminal region
CCEL_RS09065	COG2201	protein-glutamate methylesterase activity
CCEL_RS09070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCEL_RS09075	COG2264	protein methyltransferase activity
CCEL_RS09080	COG0484	heat shock protein binding
CCEL_RS09085	COG0443	Heat shock 70 kDa protein
CCEL_RS09095	COG1420	regulation of RNA biosynthetic process
CCEL_RS09110	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CCEL_RS09115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CCEL_RS09170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCEL_RS09175	COG0463	Glycosyl transferase, family 2
CCEL_RS09185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCEL_RS09235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCEL_RS09265	COG3328	transposase activity
CCEL_RS09280	COG4372	Transposase
CCEL_RS09365	COG0561	phosphatase activity
CCEL_RS09380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCEL_RS09385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCEL_RS09395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCEL_RS09400	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CCEL_RS09405	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CCEL_RS09410	COG0705	Rhomboid family
CCEL_RS09410	COG0457	Tetratricopeptide repeat
CCEL_RS09415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCEL_RS09415	COG0646	methionine synthase
CCEL_RS09420	COG0318	PFAM AMP-dependent synthetase and ligase
CCEL_RS09465	COG1592	Rubrerythrin
CCEL_RS09480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCEL_RS09485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCEL_RS09505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCEL_RS09510	COG3314	Sporulation integral membrane protein YlbJ
CCEL_RS09520	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCEL_RS09525	COG0742	ribosomal rna small subunit methyltransferase
CCEL_RS09530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCEL_RS09535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCEL_RS09545	COG3706	GGDEF domain
CCEL_RS09545	COG4251	negative regulation of phosphorylation
CCEL_RS09545	COG5001	Diguanylate cyclase
CCEL_RS09545	COG2203	Gaf domain
CCEL_RS09555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCEL_RS09560	COG0297	glycogen (starch) synthase activity
CCEL_RS09565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CCEL_RS09565	COG2199	diguanylate cyclase activity
CCEL_RS09570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCEL_RS09575	COG5002	protein histidine kinase activity
CCEL_RS09580	COG0745	RESPONSE REGULATOR receiver
CCEL_RS09590	COG0745	RESPONSE REGULATOR receiver
CCEL_RS09595	COG0750	zinc metalloprotease
CCEL_RS09600	COG0497	DNA recombination
CCEL_RS09605	COG1438	arginine binding
CCEL_RS09610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCEL_RS09615	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CCEL_RS09620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCEL_RS09635	COG1722	exodeoxyribonuclease VII activity
CCEL_RS09640	COG1570	exodeoxyribonuclease VII activity
CCEL_RS09645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCEL_RS09660	COG1302	Protein conserved in bacteria
CCEL_RS09700	COG3854	ATPases associated with a variety of cellular activities
CCEL_RS09710	COG1131	(ABC) transporter
CCEL_RS09715	COG1725	Transcriptional regulator
CCEL_RS09730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCEL_RS09735	COG0006	proline dipeptidase activity
CCEL_RS09740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCEL_RS09750	COG1362	aminopeptidase activity
CCEL_RS09755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CCEL_RS09770	COG0482	sulfurtransferase activity
CCEL_RS09775	COG0822	iron-sulfur transferase activity
CCEL_RS09785	COG1959	2 iron, 2 sulfur cluster binding
CCEL_RS09800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCEL_RS09810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCEL_RS09820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCEL_RS09825	COG0481	GTPase activity
CCEL_RS09855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCEL_RS09865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCEL_RS09870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCEL_RS09875	COG1490	D-aminoacyl-tRNA deacylase activity
CCEL_RS09880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCEL_RS09885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCEL_RS09890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CCEL_RS09890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCEL_RS09900	COG2333	competence protein COMEC
CCEL_RS09900	COG0658	competence protein
CCEL_RS09905	COG0791	NLP P60 protein
CCEL_RS09905	COG1388	LysM domain
CCEL_RS09925	COG1846	Transcriptional regulator
CCEL_RS09930	COG1511	domain protein
CCEL_RS09935	COG2873	o-acetylhomoserine
CCEL_RS09940	COG1522	sequence-specific DNA binding
CCEL_RS09950	COG0436	Aminotransferase
CCEL_RS09975	COG0697	spore germination
CCEL_RS10005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCEL_RS10020	COG0268	Binds directly to 16S ribosomal RNA
CCEL_RS10025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCEL_RS10030	COG0534	Mate efflux family protein
CCEL_RS10035	COG2207	Transcriptional regulator
CCEL_RS10035	COG4753	response regulator
CCEL_RS10040	COG3275	phosphorelay sensor kinase activity
CCEL_RS10050	COG4214	carbohydrate transport
CCEL_RS10060	COG4213	ABC transporter substrate-binding protein
CCEL_RS10070	COG0352	thiamine-phosphate diphosphorylase activity
CCEL_RS10075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCEL_RS10080	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CCEL_RS10085	COG0351	phosphomethylpyrimidine kinase
CCEL_RS10085	COG0352	thiamine-phosphate diphosphorylase activity
CCEL_RS10095	COG0735	belongs to the Fur family
CCEL_RS10125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCEL_RS10130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCEL_RS10130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCEL_RS10135	COG0307	riboflavin synthase, alpha
CCEL_RS10145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCEL_RS10175	COG2135	peptidase activity
CCEL_RS10195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS10225	COG1191	sigma factor activity
CCEL_RS10235	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CCEL_RS10240	COG1776	CheC inhibitor of MCP methylation
CCEL_RS10245	COG0835	chemotaxis
CCEL_RS10250	COG2198	Histidine kinase
CCEL_RS10250	COG0643	Histidine kinase
CCEL_RS10255	COG2201	protein-glutamate methylesterase activity
CCEL_RS10265	COG1419	protein localization to endoplasmic reticulum
CCEL_RS10270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCEL_RS10275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCEL_RS10280	COG1684	flagellar biosynthetic protein fliR
CCEL_RS10285	COG1987	bacterial-type flagellum assembly
CCEL_RS10290	COG1338	Plays a role in the flagellum-specific transport system
CCEL_RS10300	COG2201	protein-glutamate methylesterase activity
CCEL_RS10305	COG1776	CheC inhibitor of MCP methylation
CCEL_RS10305	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CCEL_RS10310	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CCEL_RS10320	COG1582	Flagellar protein (FlbD)
CCEL_RS10325	COG1749	Flagellar hook protein flgE
CCEL_RS10335	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CCEL_RS10355	COG1157	protein secretion by the type III secretion system
CCEL_RS10375	COG1677	Flagellar hook-basal body complex protein FliE
CCEL_RS10380	COG1558	bacterial-type flagellum-dependent cell motility
CCEL_RS10385	COG1815	bacterial-type flagellum-dependent cell motility
CCEL_RS10390	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CCEL_RS10395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCEL_RS10400	COG0758	DNA mediated transformation
CCEL_RS10405	COG0606	chelatase, subunit chli
CCEL_RS10410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CCEL_RS10415	COG1873	PFAM PRC-barrel domain
CCEL_RS10420	COG1191	sigma factor activity
CCEL_RS10425	COG1191	sigma factor activity
CCEL_RS10435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CCEL_RS10445	COG3856	small basic protein
CCEL_RS10450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCEL_RS10455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCEL_RS10460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCEL_RS10465	COG3442	glutamine amidotransferase
CCEL_RS10470	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CCEL_RS10480	COG0741	lytic transglycosylase activity
CCEL_RS10485	COG0237	dephospho-CoA kinase activity
CCEL_RS10490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCEL_RS10490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCEL_RS10500	COG1595	DNA-templated transcription, initiation
CCEL_RS10505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCEL_RS10520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CCEL_RS10525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCEL_RS10535	COG0569	domain protein
CCEL_RS10540	COG2323	membrane
CCEL_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS10575	COG0693	protein deglycase activity
CCEL_RS10585	COG2954	triphosphatase activity
CCEL_RS10595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CCEL_RS10600	COG0537	adenosine 5'-monophosphoramidase activity
CCEL_RS10605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCEL_RS10615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCEL_RS10620	COG0835	chemotaxis
CCEL_RS10625	COG0840	transmembrane signaling receptor activity
CCEL_RS10630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCEL_RS10635	COG0581	inorganic phosphate transmembrane transporter activity
CCEL_RS10640	COG0573	inorganic phosphate transmembrane transporter activity
CCEL_RS10645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCEL_RS10650	COG0704	Plays a role in the regulation of phosphate uptake
CCEL_RS10655	COG0745	RESPONSE REGULATOR receiver
CCEL_RS10660	COG5002	protein histidine kinase activity
CCEL_RS10670	COG3459	Glycosyltransferase 36 associated
CCEL_RS10675	COG0395	ABC-type sugar transport system, permease component
CCEL_RS10690	COG4753	response regulator
CCEL_RS10690	COG2207	Transcriptional regulator
CCEL_RS10690	COG4753	response regulator
CCEL_RS10690	COG2207	Transcriptional regulator
CCEL_RS10695	COG2972	Histidine kinase
CCEL_RS10700	COG1653	transport
CCEL_RS10705	COG0542	response to heat
CCEL_RS10710	COG0306	phosphate transporter
CCEL_RS10730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CCEL_RS10750	COG4512	PFAM Accessory gene regulator B
CCEL_RS10755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CCEL_RS10760	COG0791	NLP P60 protein
CCEL_RS10760	COG1388	LysM domain
CCEL_RS10765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCEL_RS10770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CCEL_RS10775	COG1160	GTP binding
CCEL_RS10790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCEL_RS10800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCEL_RS10805	COG0280	phosphate acetyltransferase
CCEL_RS10820	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
CCEL_RS10845	COG4191	Histidine kinase
CCEL_RS10850	COG0745	RESPONSE REGULATOR receiver
CCEL_RS10885	COG2801	Transposase and inactivated derivatives
CCEL_RS10910	COG1131	(ABC) transporter
CCEL_RS10925	COG2755	lipolytic protein G-D-S-L family
CCEL_RS10925	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS10930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCEL_RS10945	COG0402	S-adenosylhomocysteine deaminase activity
CCEL_RS10950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CCEL_RS10965	COG1187	pseudouridine synthase activity
CCEL_RS10970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCEL_RS10970	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CCEL_RS10990	COG1802	Transcriptional regulator
CCEL_RS10995	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCEL_RS11000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCEL_RS11015	COG0840	transmembrane signaling receptor activity
CCEL_RS11020	COG0151	Belongs to the GarS family
CCEL_RS11025	COG0138	bifunctional purine biosynthesis protein purh
CCEL_RS11030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCEL_RS11035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCEL_RS11040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CCEL_RS11045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CCEL_RS11065	COG1063	alcohol dehydrogenase
CCEL_RS11135	COG0519	Catalyzes the synthesis of GMP from XMP
CCEL_RS11140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCEL_RS11145	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CCEL_RS11150	COG1691	(AIR) carboxylase
CCEL_RS11155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCEL_RS11160	COG0561	phosphatase activity
CCEL_RS11165	COG0436	Aminotransferase
CCEL_RS11170	COG1522	sequence-specific DNA binding
CCEL_RS11180	COG3118	belongs to the thioredoxin family
CCEL_RS11190	COG5434	Belongs to the glycosyl hydrolase 28 family
CCEL_RS11190	COG4632	Exopolysaccharide biosynthesis protein
CCEL_RS11215	COG1924	4 iron, 4 sulfur cluster binding
CCEL_RS11230	COG1649	PFAM Uncharacterised BCR, COG1649
CCEL_RS11235	COG0191	fructose-bisphosphate aldolase activity
CCEL_RS11240	COG0205	6-phosphofructokinase activity
CCEL_RS11245	COG1882	Formate acetyltransferase
CCEL_RS11300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCEL_RS11310	COG0840	transmembrane signaling receptor activity
CCEL_RS11315	COG3906	Belongs to the UPF0473 family
CCEL_RS11320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCEL_RS11325	COG4472	Bacterial protein of unknown function (DUF965)
CCEL_RS11330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCEL_RS11350	COG1683	Conserved Protein
CCEL_RS11355	COG0557	exoribonuclease II activity
CCEL_RS11365	COG5002	protein histidine kinase activity
CCEL_RS11375	COG0726	polysaccharide deacetylase
CCEL_RS11385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCEL_RS11390	COG0148	phosphopyruvate hydratase activity
CCEL_RS11400	COG1396	sequence-specific DNA binding
CCEL_RS11415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CCEL_RS11420	COG0126	phosphoglycerate kinase activity
CCEL_RS11420	COG0149	triose-phosphate isomerase activity
CCEL_RS11470	COG0653	protein targeting
CCEL_RS11475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CCEL_RS11480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCEL_RS11505	COG2195	Cleaves the N-terminal amino acid of tripeptides
CCEL_RS11525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCEL_RS11545	COG2172	sigma factor antagonist activity
CCEL_RS11550	COG1366	Belongs to the anti-sigma-factor antagonist family
CCEL_RS11555	COG1481	regulation of sporulation
CCEL_RS11565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CCEL_RS11570	COG1660	Displays ATPase and GTPase activities
CCEL_RS11575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCEL_RS11580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CCEL_RS11585	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CCEL_RS11590	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CCEL_RS11605	COG0617	tRNA 3'-terminal CCA addition
CCEL_RS11635	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CCEL_RS11680	COG2201	protein-glutamate methylesterase activity
CCEL_RS11690	COG0840	transmembrane signaling receptor activity
CCEL_RS11695	COG0835	chemotaxis
CCEL_RS11700	COG0643	Histidine kinase
CCEL_RS11700	COG2198	Histidine kinase
CCEL_RS11705	COG2201	protein-glutamate methylesterase activity
CCEL_RS11720	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS11725	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS11730	COG4999	Histidine kinase
CCEL_RS11730	COG3850	Histidine kinase
CCEL_RS11730	COG3437	response regulator, receiver
CCEL_RS11730	COG2205	protein histidine kinase activity
CCEL_RS11745	COG0745	RESPONSE REGULATOR receiver
CCEL_RS11750	COG1819	glycosyl
CCEL_RS11755	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CCEL_RS11755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS11760	COG1819	glycosyl
CCEL_RS11770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS11780	COG3321	synthase
CCEL_RS11780	COG0300	oxidoreductase activity
CCEL_RS11780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS11780	COG0300	oxidoreductase activity
CCEL_RS11780	COG0318	PFAM AMP-dependent synthetase and ligase
CCEL_RS11780	COG3321	synthase
CCEL_RS11780	COG0318	PFAM AMP-dependent synthetase and ligase
CCEL_RS11780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS11810	COG4447	cellulose binding
CCEL_RS11810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CCEL_RS11835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCEL_RS11865	COG1131	(ABC) transporter
CCEL_RS11895	COG1136	(ABC) transporter
CCEL_RS11965	COG2801	Transposase and inactivated derivatives
CCEL_RS11975	COG1830	Aldolase
CCEL_RS11995	COG4221	oxidoreductase activity
CCEL_RS11995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS11995	COG3321	synthase
CCEL_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS12050	COG1032	radical SAM domain protein
CCEL_RS12055	COG3848	Pyruvate phosphate dikinase
CCEL_RS12055	COG0574	Belongs to the PEP-utilizing enzyme family
CCEL_RS12075	COG5297	Belongs to the glycosyl hydrolase family 6
CCEL_RS12075	COG2273	Hydrolase Family 16
CCEL_RS12085	COG2223	nitrite transmembrane transporter activity
CCEL_RS12100	COG5444	nuclease activity
CCEL_RS12125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCEL_RS12135	COG2133	pyrroloquinoline quinone binding
CCEL_RS12135	COG5183	chlorophyll binding
CCEL_RS12180	COG1459	type II secretion system
CCEL_RS12190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCEL_RS12215	COG1573	uracil-dna glycosylase
CCEL_RS12220	COG1573	uracil-dna glycosylase
CCEL_RS12260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCEL_RS12270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CCEL_RS12290	COG0745	RESPONSE REGULATOR receiver
CCEL_RS12295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCEL_RS12300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCEL_RS12305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCEL_RS12310	COG0116	Belongs to the methyltransferase superfamily
CCEL_RS12315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCEL_RS12320	COG0564	pseudouridine synthase activity
CCEL_RS12325	COG0116	Belongs to the methyltransferase superfamily
CCEL_RS12325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCEL_RS12335	COG0010	Belongs to the arginase family
CCEL_RS12340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCEL_RS12345	COG0154	amidase activity
CCEL_RS12350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCEL_RS12355	COG0367	asparagine synthase
CCEL_RS12370	COG0367	asparagine synthase
CCEL_RS12380	COG0475	glutathione-regulated potassium exporter activity
CCEL_RS12400	COG0723	plastoquinol--plastocyanin reductase activity
CCEL_RS12400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCEL_RS12410	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CCEL_RS12415	COG1874	Beta-galactosidase
CCEL_RS12420	COG2207	Transcriptional regulator
CCEL_RS12420	COG4753	response regulator
CCEL_RS12425	COG2972	Histidine kinase
CCEL_RS12430	COG1472	Belongs to the glycosyl hydrolase 3 family
CCEL_RS12435	COG1501	Belongs to the glycosyl hydrolase 31 family
CCEL_RS12440	COG4209	transmembrane transport
CCEL_RS12445	COG0395	ABC-type sugar transport system, permease component
CCEL_RS12470	COG0681	Belongs to the peptidase S26 family
CCEL_RS12485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCEL_RS12505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCEL_RS12520	COG1022	Amp-dependent synthetase and ligase
CCEL_RS12530	COG0646	methionine synthase
CCEL_RS12530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCEL_RS12535	COG0768	penicillin binding
CCEL_RS12545	COG1716	ATPase activity
CCEL_RS12560	COG0546	phosphoglycolate phosphatase activity
CCEL_RS12565	COG2814	Major facilitator Superfamily
CCEL_RS12570	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCEL_RS12575	COG2703	oxygen carrier activity
CCEL_RS12580	COG0039	L-malate dehydrogenase activity
CCEL_RS12585	COG0371	Dehydrogenase
CCEL_RS12645	COG2267	carboxylic ester hydrolase activity
CCEL_RS12650	COG0733	neurotransmitter:sodium symporter activity
CCEL_RS12670	COG0656	L-ascorbic acid biosynthetic process
CCEL_RS12680	COG2199	diguanylate cyclase activity
CCEL_RS12680	COG2203	Gaf domain
CCEL_RS12700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS12715	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CCEL_RS12735	COG0318	PFAM AMP-dependent synthetase and ligase
CCEL_RS12745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS12750	COG0737	Belongs to the 5'-nucleotidase family
CCEL_RS12765	COG4555	ABC transporter
CCEL_RS12785	COG0840	transmembrane signaling receptor activity
CCEL_RS12795	COG2814	Major facilitator Superfamily
CCEL_RS12825	COG0019	diaminopimelate decarboxylase activity
CCEL_RS12845	COG0714	Associated with various cellular activities
CCEL_RS12855	COG0730	response to heat
CCEL_RS12860	COG0628	permease
CCEL_RS12865	COG1408	metallophosphoesterase
CCEL_RS12880	COG0493	'glutamate synthase
CCEL_RS12890	COG1994	Peptidase M50
CCEL_RS12935	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CCEL_RS12940	COG2894	cell division
CCEL_RS12945	COG0850	regulation of cytokinetic process
CCEL_RS12950	COG0768	penicillin binding
CCEL_RS12965	COG1077	Cell shape determining protein MreB Mrl
CCEL_RS12970	COG2003	Belongs to the UPF0758 family
CCEL_RS12975	COG0424	maF-like protein
CCEL_RS12980	COG4862	establishment of competence for transformation
CCEL_RS12985	COG0473	3-isopropylmalate dehydrogenase activity
CCEL_RS12990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCEL_RS13000	COG0733	neurotransmitter:sodium symporter activity
CCEL_RS13005	COG0372	Belongs to the citrate synthase family
CCEL_RS13010	COG0653	protein targeting
CCEL_RS13020	COG0017	Asparaginyl-tRNA synthetase
CCEL_RS13025	COG2502	aspartate--ammonia ligase
CCEL_RS13030	COG0538	isocitrate dehydrogenase activity
CCEL_RS13035	COG3459	Glycosyltransferase 36 associated
CCEL_RS13055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCEL_RS13075	COG0501	Belongs to the peptidase M48B family
CCEL_RS13080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CCEL_RS13090	COG0765	amino acid transport
CCEL_RS13095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCEL_RS13100	COG1376	ErfK ybiS ycfS ynhG family protein
CCEL_RS13115	COG0251	oxidation-reduction process
CCEL_RS13120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCEL_RS13125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCEL_RS13150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCEL_RS13165	COG1725	Transcriptional regulator
CCEL_RS13170	COG1131	(ABC) transporter
CCEL_RS13185	COG1131	(ABC) transporter
CCEL_RS13210	COG0688	phosphatidylethanolamine metabolic process
CCEL_RS13220	COG2226	methyltransferase
CCEL_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS13240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCEL_RS13280	COG4372	Transposase
CCEL_RS13285	COG1131	(ABC) transporter
CCEL_RS13315	COG1361	Conserved repeat domain
CCEL_RS13330	COG0840	transmembrane signaling receptor activity
CCEL_RS13330	COG3290	protein histidine kinase activity
CCEL_RS13355	COG1404	Belongs to the peptidase S8 family
CCEL_RS13405	COG0154	amidase activity
CCEL_RS13415	COG1289	transmembrane transporter activity
CCEL_RS13420	COG5002	protein histidine kinase activity
CCEL_RS13430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCEL_RS13465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCEL_RS13475	COG2382	esterase
CCEL_RS13475	COG3507	Belongs to the glycosyl hydrolase 43 family
CCEL_RS13475	COG3693	PFAM glycoside hydrolase, family 10
CCEL_RS13525	COG3708	Transcriptional regulator
CCEL_RS13525	COG2207	Transcriptional regulator
CCEL_RS13545	COG4214	carbohydrate transport
CCEL_RS13560	COG4213	ABC transporter substrate-binding protein
CCEL_RS13565	COG1349	DNA-binding transcription factor activity
CCEL_RS13660	COG1136	(ABC) transporter
CCEL_RS13680	COG4372	Transposase
CCEL_RS13795	COG1191	sigma factor activity
CCEL_RS13830	COG0798	PFAM Bile acid sodium symporter
CCEL_RS13870	COG1388	LysM domain
CCEL_RS13870	COG3103	Sh3 type 3 domain protein
CCEL_RS13870	COG0791	NLP P60 protein
CCEL_RS13880	COG3344	reverse transcriptase
CCEL_RS13910	COG1741	Belongs to the pirin family
CCEL_RS14005	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CCEL_RS14015	COG2088	sporulation resulting in formation of a cellular spore
CCEL_RS14025	COG2911	Protein conserved in bacteria
CCEL_RS14025	COG3266	domain, Protein
CCEL_RS14025	COG1361	Conserved repeat domain
CCEL_RS14060	COG1396	sequence-specific DNA binding
CCEL_RS14070	COG3620	sequence-specific DNA binding
CCEL_RS14100	COG2226	methyltransferase
CCEL_RS14125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCEL_RS14125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCEL_RS14140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CCEL_RS14145	COG0500	methyltransferase
CCEL_RS14165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCEL_RS14195	COG3858	chitin binding
CCEL_RS14265	COG0740	serine-type endopeptidase activity
CCEL_RS14270	COG4695	Portal protein
CCEL_RS14275	COG1802	Transcriptional regulator
CCEL_RS14275	COG4626	Terminase
CCEL_RS14305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCEL_RS14350	COG3561	AntA/AntB antirepressor
CCEL_RS14365	COG3226	Transcriptional regulator
CCEL_RS14370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCEL_RS14370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCEL_RS14455	COG0840	transmembrane signaling receptor activity
CCEL_RS14460	COG0739	heme binding
CCEL_RS14485	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CCEL_RS14490	COG0287	Prephenate dehydrogenase
CCEL_RS14495	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CCEL_RS14500	COG0438	transferase activity, transferring glycosyl groups
CCEL_RS14505	COG0488	(ABC) transporter
CCEL_RS14515	COG0840	transmembrane signaling receptor activity
CCEL_RS14525	COG0840	transmembrane signaling receptor activity
CCEL_RS14535	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCEL_RS14610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCEL_RS14615	COG1278	Cold shock
CCEL_RS14620	COG2226	methyltransferase
CCEL_RS14630	COG3409	Peptidoglycan-binding domain 1 protein
CCEL_RS14630	COG0793	Belongs to the peptidase S41A family
CCEL_RS14635	COG0739	heme binding
CCEL_RS14640	COG2177	Part of the ABC transporter FtsEX involved in
CCEL_RS14645	COG2884	Cell division ATP-binding protein ftsE
CCEL_RS14650	COG3835	regulator
CCEL_RS14655	COG3842	ATPase activity
CCEL_RS14660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCEL_RS14665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCEL_RS14670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCEL_RS14675	COG0505	Belongs to the CarA family
CCEL_RS14680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCEL_RS14685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCEL_RS14690	COG2153	protein acetylation
CCEL_RS14700	COG1151	hydroxylamine reductase activity
CCEL_RS14710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CCEL_RS14730	COG2337	Toxic component of a toxin-antitoxin (TA) module
CCEL_RS14735	COG0864	Transcriptional regulator
CCEL_RS14740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCEL_RS14745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCEL_RS14745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCEL_RS14780	COG0772	Belongs to the SEDS family
CCEL_RS14785	COG1695	Transcriptional regulator
CCEL_RS14795	COG2816	NAD+ diphosphatase activity
CCEL_RS14805	COG2244	polysaccharide biosynthetic process
CCEL_RS14810	COG0791	NLP P60 protein
CCEL_RS14810	COG1388	LysM domain
CCEL_RS14815	COG2247	cell wall binding repeat
CCEL_RS14815	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCEL_RS14820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCEL_RS14835	COG2337	Toxic component of a toxin-antitoxin (TA) module
CCEL_RS14950	COG4372	Transposase
CCEL_RS15020	COG2208	phosphoserine phosphatase activity
CCEL_RS15025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CCEL_RS15055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCEL_RS15065	COG1550	Protein conserved in bacteria
CCEL_RS15075	COG1671	Belongs to the UPF0178 family
CCEL_RS15080	COG0395	ABC-type sugar transport system, permease component
CCEL_RS15085	COG1175	transmembrane transport
CCEL_RS15090	COG2182	Extracellular solute-binding protein
CCEL_RS15105	COG1609	Transcriptional regulator
CCEL_RS15110	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CCEL_RS15115	COG2942	2-epimerase
CCEL_RS15120	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CCEL_RS15130	COG0701	Predicted permease
CCEL_RS15135	COG0523	cobalamin synthesis protein
CCEL_RS15145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCEL_RS15165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CCEL_RS15180	COG0697	spore germination
CCEL_RS15345	COG5484	DNA packaging
CCEL_RS15345	COG3728	DNA packaging
CCEL_RS15435	COG2002	toxin-antitoxin pair type II binding
CCEL_RS15460	COG1396	sequence-specific DNA binding
CCEL_RS15475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCEL_RS15485	COG1098	S1 RNA binding domain
CCEL_RS15505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCEL_RS15515	COG3956	TIGRFAM MazG family protein
CCEL_RS15525	COG2002	toxin-antitoxin pair type II binding
CCEL_RS15530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCEL_RS15535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCEL_RS15550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCEL_RS15555	COG2088	sporulation resulting in formation of a cellular spore
CCEL_RS15560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCEL_RS15565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCEL_RS15570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCEL_RS15580	COG3951	Flagellar rod assembly protein muramidase FlgJ
CCEL_RS15590	COG4786	Flagellar basal body rod
CCEL_RS15600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CCEL_RS15620	COG0475	glutathione-regulated potassium exporter activity
CCEL_RS15625	COG0490	domain, Protein
CCEL_RS15630	COG1609	Transcriptional regulator
CCEL_RS15660	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CCEL_RS15720	COG2002	toxin-antitoxin pair type II binding
CCEL_RS15880	COG1475	DNA binding
CCEL_RS15885	COG1192	Involved in chromosome partitioning
CCEL_RS15955	COG1819	glycosyl
CCEL_RS15965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCEL_RS15975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CCEL_RS15990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCEL_RS15995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCEL_RS16015	COG1802	Transcriptional regulator
CCEL_RS16025	COG3485	protocatechuate 3,4-dioxygenase
CCEL_RS16035	COG3485	protocatechuate 3,4-dioxygenase
CCEL_RS16040	COG1454	alcohol dehydrogenase
CCEL_RS16040	COG1012	belongs to the aldehyde dehydrogenase family
CCEL_RS16045	COG5012	cobalamin binding
CCEL_RS16065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCEL_RS16070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCEL_RS16075	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CCEL_RS16080	COG2843	Capsule synthesis protein
CCEL_RS16085	COG1368	sulfuric ester hydrolase activity
CCEL_RS16120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCEL_RS16120	COG0512	Glutamine amidotransferase of anthranilate synthase
CCEL_RS16125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCEL_RS16130	COG0134	indole-3-glycerol-phosphate synthase activity
CCEL_RS16140	COG0133	tryptophan synthase activity
CCEL_RS16145	COG0159	tryptophan synthase activity
CCEL_RS16150	COG4989	oxidoreductase activity
CCEL_RS16165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCEL_RS16170	COG1063	alcohol dehydrogenase
CCEL_RS16175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCEL_RS16185	COG2357	RelA SpoT domain protein
CCEL_RS16195	COG0488	(ABC) transporter
CCEL_RS16205	COG1268	BioY protein
CCEL_RS16220	COG0840	transmembrane signaling receptor activity
CCEL_RS16235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCEL_RS16240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCEL_RS16255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCEL_RS16265	COG0395	ABC-type sugar transport system, permease component
CCEL_RS16270	COG1175	transmembrane transport
CCEL_RS16285	COG2972	Histidine kinase
CCEL_RS16290	COG2207	Transcriptional regulator
CCEL_RS16290	COG4753	response regulator
CCEL_RS16295	COG0667	Aldo Keto reductase
CCEL_RS16305	COG0318	PFAM AMP-dependent synthetase and ligase
CCEL_RS16310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS16335	COG0037	tRNA processing
CCEL_RS16340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCEL_RS16365	COG3708	Transcriptional regulator
CCEL_RS16365	COG2207	Transcriptional regulator
CCEL_RS16370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCEL_RS16520	COG3728	DNA packaging
CCEL_RS16520	COG5484	DNA packaging
CCEL_RS16565	COG1475	DNA binding
CCEL_RS16585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCEL_RS16595	COG2002	toxin-antitoxin pair type II binding
CCEL_RS16630	COG4974	Belongs to the 'phage' integrase family
CCEL_RS16650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCEL_RS16660	COG0708	Exodeoxyribonuclease III
CCEL_RS16670	COG0215	cysteine-tRNA ligase activity
CCEL_RS16675	COG1045	serine acetyltransferase
CCEL_RS16705	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CCEL_RS16715	COG1174	glycine betaine transport
CCEL_RS16735	COG1979	alcohol dehydrogenase
CCEL_RS16740	COG0789	Transcriptional regulator
CCEL_RS16760	COG2155	Conserved Protein
CCEL_RS16770	COG0628	permease
CCEL_RS16805	COG1132	(ABC) transporter
CCEL_RS16825	COG0668	transmembrane transport
CCEL_RS16830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CCEL_RS16835	COG1773	rubredoxin
CCEL_RS16860	COG0024	Methionine aminopeptidase
CCEL_RS16870	COG2860	membrane
CCEL_RS16875	COG0375	protein maturation
CCEL_RS16885	COG3261	NADH dehydrogenase
CCEL_RS16885	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CCEL_RS16890	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCEL_RS16895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCEL_RS16900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCEL_RS16905	COG2111	Na H antiporter
CCEL_RS16905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCEL_RS16910	COG0628	permease
CCEL_RS16915	COG2890	protein-(glutamine-N5) methyltransferase activity
CCEL_RS16920	COG3872	metal-dependent enzyme
CCEL_RS16925	COG0254	rRNA binding
CCEL_RS16930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CCEL_RS16955	COG0813	purine-nucleoside phosphorylase activity
CCEL_RS16960	COG1368	sulfuric ester hydrolase activity
CCEL_RS16965	COG0784	Response regulator, receiver
CCEL_RS16965	COG5002	protein histidine kinase activity
CCEL_RS16965	COG2205	protein histidine kinase activity
CCEL_RS16970	COG2235	arginine
CCEL_RS16975	COG0534	Mate efflux family protein
CCEL_RS16985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CCEL_RS16990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CCEL_RS16995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCEL_RS17015	COG5002	protein histidine kinase activity
CCEL_RS17020	COG0745	RESPONSE REGULATOR receiver
CCEL_RS17040	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCEL_RS17050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CCEL_RS17055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CCEL_RS17060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCEL_RS17080	COG0037	tRNA processing
CCEL_RS17090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCEL_RS17120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCEL_RS17125	COG1121	(ABC) transporter
CCEL_RS17140	COG3655	Transcriptional regulator
CCEL_RS17165	COG3973	AAA domain
CCEL_RS17190	COG4106	trans-aconitate 2-methyltransferase activity
CCEL_RS17195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCEL_RS17200	COG1486	melibiose metabolic process
CCEL_RS17205	COG0778	Nitroreductase
CCEL_RS17205	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CCEL_RS17210	COG2207	Transcriptional regulator
CCEL_RS17215	COG2115	Belongs to the xylose isomerase family
CCEL_RS17220	COG1940	carbohydrate kinase activity
CCEL_RS17225	COG1070	Carbohydrate kinase
CCEL_RS17235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCEL_RS17240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCEL_RS17245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCEL_RS17250	COG0440	acetolactate synthase activity
CCEL_RS17255	COG0028	Belongs to the TPP enzyme family
CCEL_RS17270	COG0590	tRNA wobble adenosine to inosine editing
CCEL_RS17280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCEL_RS17315	COG0022	dehydrogenase e1 component
CCEL_RS17320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CCEL_RS17330	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CCEL_RS17330	COG0662	Cupin 2, conserved barrel domain protein
CCEL_RS17340	COG0495	leucyl-tRNA aminoacylation
CCEL_RS17355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCEL_RS17360	COG2309	aminopeptidase activity
CCEL_RS17365	COG1164	Oligoendopeptidase f
CCEL_RS17390	COG1609	Transcriptional regulator
CCEL_RS17420	COG1609	Transcriptional regulator
CCEL_RS17425	COG0432	Pfam Uncharacterised protein family UPF0047
CCEL_RS17430	COG1489	DNA binding
CCEL_RS17460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCEL_RS17465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CCEL_RS17500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CCEL_RS17505	COG1475	DNA binding
CCEL_RS17510	COG0357	Ribosomal RNA small subunit methyltransferase G
CCEL_RS17515	COG0445	tRNA wobble uridine modification
CCEL_RS17520	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CCEL_RS17525	COG1847	R3H domain protein
CCEL_RS17530	COG0706	membrane insertase activity
CCEL_RS17535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CCEL_RS17540	COG0594	ribonuclease P activity
CCEL_RS17545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CCEL_RS17570	COG0653	protein targeting
CCEL_RS17585	COG3321	synthase
CCEL_RS17585	COG4221	oxidoreductase activity
CCEL_RS17585	COG0300	oxidoreductase activity
CCEL_RS17585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS17590	COG0300	oxidoreductase activity
CCEL_RS17590	COG4221	oxidoreductase activity
CCEL_RS17590	COG3321	synthase
CCEL_RS17590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS17595	COG3321	synthase
CCEL_RS17595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS17595	COG4221	oxidoreductase activity
CCEL_RS17595	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS17600	COG0318	PFAM AMP-dependent synthetase and ligase
CCEL_RS17600	COG0300	oxidoreductase activity
CCEL_RS17600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCEL_RS17600	COG3321	synthase
CCEL_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
CCEL_RS17605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS17610	COG3321	synthase
CCEL_RS17610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCEL_RS17610	COG0300	oxidoreductase activity
CCEL_RS17610	COG4221	oxidoreductase activity
CCEL_RS17615	COG4193	domain, Protein
CCEL_RS17615	COG5632	N-Acetylmuramoyl-L-alanine amidase
CCEL_RS17615	COG3266	domain, Protein
CCEL_RS17625	COG0765	amino acid transport
CCEL_RS17690	COG2801	Transposase and inactivated derivatives
CCEL_RS17750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair