locus-tag	class	description
A7L45_RS00010	COG0592	DNA-directed DNA polymerase activity
A7L45_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A7L45_RS00030	COG0187	DNA topoisomerase II activity
A7L45_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7L45_RS00070	COG1827	regulation of RNA biosynthetic process
A7L45_RS00075	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
A7L45_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A7L45_RS00130	COG0791	NLP P60 protein
A7L45_RS00145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A7L45_RS00160	COG2703	oxygen carrier activity
A7L45_RS00165	COG0789	Transcriptional regulator
A7L45_RS00170	COG0477	Major facilitator Superfamily
A7L45_RS00175	COG0840	transmembrane signaling receptor activity
A7L45_RS00200	COG0590	tRNA wobble adenosine to inosine editing
A7L45_RS00210	COG1349	DNA-binding transcription factor activity
A7L45_RS00215	COG1105	Belongs to the carbohydrate kinase PfkB family
A7L45_RS00220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS00220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7L45_RS00220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7L45_RS00245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7L45_RS00290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7L45_RS00325	COG2816	NAD+ diphosphatase activity
A7L45_RS00345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7L45_RS00350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7L45_RS00360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7L45_RS00390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A7L45_RS00395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7L45_RS00425	COG0668	transmembrane transport
A7L45_RS00445	COG0840	transmembrane signaling receptor activity
A7L45_RS00455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7L45_RS00510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7L45_RS00560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7L45_RS00605	COG1982	Orn Lys Arg decarboxylase major
A7L45_RS00610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A7L45_RS00615	COG3870	Protein conserved in bacteria
A7L45_RS00620	COG0470	DNA polymerase III
A7L45_RS00625	COG1774	PSP1 C-terminal conserved region
A7L45_RS00650	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7L45_RS00655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7L45_RS00660	COG1388	LysM domain
A7L45_RS00660	COG0791	NLP P60 protein
A7L45_RS00670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A7L45_RS00675	COG1187	pseudouridine synthase activity
A7L45_RS00685	COG5002	protein histidine kinase activity
A7L45_RS00715	COG2715	membrane protein required for spore maturation
A7L45_RS00720	COG0700	Nucleoside recognition
A7L45_RS00725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7L45_RS00725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7L45_RS00730	COG4399	Belongs to the UPF0754 family
A7L45_RS00735	COG0084	hydrolase, TatD family'
A7L45_RS00740	COG3584	3D domain protein
A7L45_RS00740	COG3583	domain protein
A7L45_RS00780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7L45_RS00785	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7L45_RS00795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A7L45_RS00805	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A7L45_RS00840	COG0577	efflux transmembrane transporter activity
A7L45_RS00840	COG1136	(ABC) transporter
A7L45_RS00845	COG0577	efflux transmembrane transporter activity
A7L45_RS00865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7L45_RS00875	COG0473	3-isopropylmalate dehydrogenase activity
A7L45_RS00880	COG1187	pseudouridine synthase activity
A7L45_RS00915	COG2340	Cysteine-rich secretory protein family
A7L45_RS00935	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS00940	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS00945	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
A7L45_RS00950	COG1691	(AIR) carboxylase
A7L45_RS00955	COG0281	malic enzyme
A7L45_RS00960	COG0583	DNA-binding transcription factor activity
A7L45_RS00965	COG1131	(ABC) transporter
A7L45_RS01025	COG4466	Protein conserved in bacteria
A7L45_RS01035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A7L45_RS01045	COG0697	spore germination
A7L45_RS01050	COG0814	amino acid
A7L45_RS01065	COG2959	enzyme of heme biosynthesis
A7L45_RS01070	COG1181	Belongs to the D-alanine--D-alanine ligase family
A7L45_RS01075	COG0482	sulfurtransferase activity
A7L45_RS01090	COG0504	CTP synthase activity
A7L45_RS01095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7L45_RS01105	COG1435	thymidine kinase activity
A7L45_RS01110	COG3872	metal-dependent enzyme
A7L45_RS01130	COG0009	L-threonylcarbamoyladenylate synthase
A7L45_RS01140	COG0698	ribose 5-phosphate isomerase
A7L45_RS01145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A7L45_RS01150	COG1592	Rubrerythrin
A7L45_RS01150	COG1773	rubredoxin
A7L45_RS01170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7L45_RS01175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7L45_RS01185	COG0356	it plays a direct role in the translocation of protons across the membrane
A7L45_RS01190	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7L45_RS01195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A7L45_RS01210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A7L45_RS01215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A7L45_RS01220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A7L45_RS01235	COG2385	sporulation resulting in formation of a cellular spore
A7L45_RS01245	COG1609	Transcriptional regulator
A7L45_RS01250	COG1077	Cell shape determining protein MreB Mrl
A7L45_RS01295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7L45_RS01305	COG1040	competence protein
A7L45_RS01320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A7L45_RS01335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7L45_RS01345	COG2183	response to ionizing radiation
A7L45_RS01355	COG2801	Transposase and inactivated derivatives
A7L45_RS01365	COG0456	acetyltransferase
A7L45_RS01370	COG1214	PFAM Peptidase M22, glycoprotease
A7L45_RS01375	COG0802	atpase or kinase
A7L45_RS01390	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7L45_RS01395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7L45_RS01400	COG1045	serine acetyltransferase
A7L45_RS01410	COG2937	Belongs to the GPAT DAPAT family
A7L45_RS01415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7L45_RS01425	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7L45_RS01430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7L45_RS01440	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
A7L45_RS01450	COG1704	LemA family
A7L45_RS01460	COG0651	ATP synthesis coupled electron transport
A7L45_RS01465	COG0650	Formate hydrogenlyase subunit 4
A7L45_RS01475	COG0651	ATP synthesis coupled electron transport
A7L45_RS01480	COG0649	NAD binding
A7L45_RS01485	COG3260	NADH ubiquinone oxidoreductase 20
A7L45_RS01495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7L45_RS01520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A7L45_RS01525	COG3730	PTS system glucitol sorbitol-specific
A7L45_RS01530	COG3732	PTS system glucitol sorbitol-specific
A7L45_RS01590	COG0488	(ABC) transporter
A7L45_RS01595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A7L45_RS01600	COG1024	Enoyl-CoA hydratase
A7L45_RS01605	COG1960	acyl-CoA dehydrogenase activity
A7L45_RS01610	COG2086	electron transfer activity
A7L45_RS01615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7L45_RS01620	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7L45_RS01635	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A7L45_RS01635	COG0493	'glutamate synthase
A7L45_RS01660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A7L45_RS01665	COG0459	protein refolding
A7L45_RS01670	COG0517	IMP dehydrogenase activity
A7L45_RS01670	COG0516	GMP reductase activity
A7L45_RS01675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7L45_RS01675	COG0519	Catalyzes the synthesis of GMP from XMP
A7L45_RS01680	COG0861	Integral membrane protein TerC family
A7L45_RS01700	COG2801	Transposase and inactivated derivatives
A7L45_RS01710	COG1388	LysM domain
A7L45_RS01710	COG3858	chitin binding
A7L45_RS01715	COG1671	Belongs to the UPF0178 family
A7L45_RS01725	COG1187	pseudouridine synthase activity
A7L45_RS01730	COG0557	exoribonuclease II activity
A7L45_RS01735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A7L45_RS01760	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
A7L45_RS01765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A7L45_RS01790	COG2003	Belongs to the UPF0758 family
A7L45_RS01850	COG2801	Transposase and inactivated derivatives
A7L45_RS01870	COG0745	RESPONSE REGULATOR receiver
A7L45_RS01885	COG2205	protein histidine kinase activity
A7L45_RS01890	COG1695	Transcriptional regulator
A7L45_RS01915	COG0246	Mannitol dehydrogenase
A7L45_RS01930	COG1802	Transcriptional regulator
A7L45_RS01935	COG1063	alcohol dehydrogenase
A7L45_RS01940	COG1312	Catalyzes the dehydration of D-mannonate
A7L45_RS01950	COG1309	transcriptional regulator
A7L45_RS01955	COG5278	phosphoserine phosphatase activity
A7L45_RS01955	COG0840	transmembrane signaling receptor activity
A7L45_RS01965	COG2076	Multidrug Resistance protein
A7L45_RS01975	COG1268	BioY protein
A7L45_RS01980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A7L45_RS01995	COG2022	thiamine diphosphate biosynthetic process
A7L45_RS02005	COG0352	thiamine-phosphate diphosphorylase activity
A7L45_RS02010	COG4086	secreted protein
A7L45_RS02015	COG0745	RESPONSE REGULATOR receiver
A7L45_RS02030	COG2205	protein histidine kinase activity
A7L45_RS02035	COG0531	amino acid
A7L45_RS02050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A7L45_RS02060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7L45_RS02065	COG0745	RESPONSE REGULATOR receiver
A7L45_RS02070	COG2205	protein histidine kinase activity
A7L45_RS02075	COG1136	(ABC) transporter
A7L45_RS02085	COG0596	Alpha beta hydrolase
A7L45_RS02090	COG0745	RESPONSE REGULATOR receiver
A7L45_RS02100	COG0745	RESPONSE REGULATOR receiver
A7L45_RS02105	COG5002	protein histidine kinase activity
A7L45_RS02105	COG3850	Histidine kinase
A7L45_RS02115	COG2801	Transposase and inactivated derivatives
A7L45_RS02135	COG0745	RESPONSE REGULATOR receiver
A7L45_RS02140	COG0642	Histidine kinase
A7L45_RS02145	COG1136	(ABC) transporter
A7L45_RS02150	COG0577	efflux transmembrane transporter activity
A7L45_RS02160	COG1132	(ABC) transporter
A7L45_RS02165	COG1132	(ABC) transporter
A7L45_RS02225	COG3711	transcriptional antiterminator
A7L45_RS02240	COG1960	acyl-CoA dehydrogenase activity
A7L45_RS02255	COG0426	domain, Protein
A7L45_RS02265	COG1609	Transcriptional regulator
A7L45_RS02270	COG1028	Short-chain dehydrogenase reductase Sdr
A7L45_RS02290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A7L45_RS02295	COG1136	(ABC) transporter
A7L45_RS02300	COG0577	efflux transmembrane transporter activity
A7L45_RS02305	COG2030	dehydratase
A7L45_RS02310	COG2610	gluconate transmembrane transporter activity
A7L45_RS02320	COG2610	gluconate transmembrane transporter activity
A7L45_RS02330	COG2030	dehydratase
A7L45_RS02335	COG4670	ketone body catabolic process
A7L45_RS02340	COG3829	transcription factor binding
A7L45_RS02340	COG3290	protein histidine kinase activity
A7L45_RS02345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7L45_RS02350	COG2086	electron transfer activity
A7L45_RS02355	COG1960	acyl-CoA dehydrogenase activity
A7L45_RS02370	COG0697	spore germination
A7L45_RS02375	COG0366	Alpha amylase catalytic
A7L45_RS02380	COG1609	Transcriptional regulator
A7L45_RS02385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS02395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A7L45_RS02405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A7L45_RS02405	COG1328	CTP reductase activity
A7L45_RS02415	COG1141	Ferredoxin
A7L45_RS02420	COG3829	transcription factor binding
A7L45_RS02420	COG3290	protein histidine kinase activity
A7L45_RS02425	COG0183	Belongs to the thiolase family
A7L45_RS02430	COG0398	Pfam SNARE associated Golgi protein
A7L45_RS02435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7L45_RS02440	COG1183	phosphatidylcholine synthase activity
A7L45_RS02445	COG0726	polysaccharide deacetylase
A7L45_RS02450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A7L45_RS02475	COG0583	DNA-binding transcription factor activity
A7L45_RS02480	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7L45_RS02485	COG0531	amino acid
A7L45_RS02495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7L45_RS02505	COG2720	vancomycin resistance protein
A7L45_RS02520	COG1937	Protein conserved in bacteria
A7L45_RS02525	COG2217	Heavy metal translocating P-type atpase
A7L45_RS02545	COG1575	Belongs to the MenA family. Type 1 subfamily
A7L45_RS02565	COG0142	geranyltranstransferase activity
A7L45_RS02570	COG0784	Response regulator, receiver
A7L45_RS02570	COG2205	protein histidine kinase activity
A7L45_RS02585	COG0745	RESPONSE REGULATOR receiver
A7L45_RS02590	COG5002	protein histidine kinase activity
A7L45_RS02595	COG0671	phosphoesterase, PA-phosphatase related
A7L45_RS02600	COG0586	Pfam SNARE associated Golgi protein
A7L45_RS02620	COG1592	Rubrerythrin
A7L45_RS02625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7L45_RS02635	COG1346	cytolysis
A7L45_RS02655	COG4716	Myosin-crossreactive antigen
A7L45_RS02660	COG2203	Gaf domain
A7L45_RS02660	COG3706	GGDEF domain
A7L45_RS02660	COG5001	Diguanylate cyclase
A7L45_RS02660	COG4251	negative regulation of phosphorylation
A7L45_RS02670	COG1924	4 iron, 4 sulfur cluster binding
A7L45_RS02720	COG3655	Transcriptional regulator
A7L45_RS02730	COG3546	catalase activity
A7L45_RS02750	COG0667	Aldo Keto reductase
A7L45_RS02755	COG1278	Cold shock
A7L45_RS02760	COG0667	Aldo Keto reductase
A7L45_RS02765	COG3773	Cell wall hydrolase
A7L45_RS02770	COG0706	membrane insertase activity
A7L45_RS02800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7L45_RS02805	COG1012	belongs to the aldehyde dehydrogenase family
A7L45_RS02810	COG1615	UPF0182 protein
A7L45_RS02815	COG0534	Mate efflux family protein
A7L45_RS02845	COG1686	Belongs to the peptidase S11 family
A7L45_RS02855	COG2801	Transposase and inactivated derivatives
A7L45_RS02865	COG0840	transmembrane signaling receptor activity
A7L45_RS02895	COG4689	acetoacetate decarboxylase
A7L45_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
A7L45_RS02910	COG0531	amino acid
A7L45_RS02915	COG2205	protein histidine kinase activity
A7L45_RS02935	COG1278	Cold shock
A7L45_RS02945	COG1131	(ABC) transporter
A7L45_RS02970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A7L45_RS02975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A7L45_RS02985	COG1695	Transcriptional regulator
A7L45_RS03000	COG5002	protein histidine kinase activity
A7L45_RS03005	COG2843	Capsule synthesis protein
A7L45_RS03010	COG2040	homocysteine
A7L45_RS03015	COG0833	amino acid
A7L45_RS03025	COG1131	(ABC) transporter
A7L45_RS03050	COG2814	Major facilitator Superfamily
A7L45_RS03060	COG1794	racemase activity, acting on amino acids and derivatives
A7L45_RS03075	COG1733	regulation of RNA biosynthetic process
A7L45_RS03085	COG1131	(ABC) transporter
A7L45_RS03095	COG1114	Component of the transport system for branched-chain amino acids
A7L45_RS03105	COG1733	regulation of RNA biosynthetic process
A7L45_RS03130	COG1404	Belongs to the peptidase S8 family
A7L45_RS03135	COG3681	Belongs to the UPF0597 family
A7L45_RS03140	COG0745	RESPONSE REGULATOR receiver
A7L45_RS03145	COG2205	protein histidine kinase activity
A7L45_RS03160	COG1131	(ABC) transporter
A7L45_RS03170	COG3835	regulator
A7L45_RS03175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7L45_RS03185	COG1114	Component of the transport system for branched-chain amino acids
A7L45_RS03220	COG0840	transmembrane signaling receptor activity
A7L45_RS03225	COG0745	RESPONSE REGULATOR receiver
A7L45_RS03230	COG5002	protein histidine kinase activity
A7L45_RS03245	COG0726	polysaccharide deacetylase
A7L45_RS03260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A7L45_RS03270	COG0039	L-malate dehydrogenase activity
A7L45_RS03285	COG1132	(ABC) transporter
A7L45_RS03290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7L45_RS03300	COG1360	Flagellar Motor Protein
A7L45_RS03305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A7L45_RS03310	COG0671	phosphoesterase, PA-phosphatase related
A7L45_RS03335	COG0698	ribose 5-phosphate isomerase
A7L45_RS03340	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A7L45_RS03360	COG5002	protein histidine kinase activity
A7L45_RS03450	COG0006	proline dipeptidase activity
A7L45_RS03465	COG0693	protein deglycase activity
A7L45_RS03470	COG0488	(ABC) transporter
A7L45_RS03475	COG0626	cystathionine gamma-synthase activity
A7L45_RS03480	COG1053	succinate dehydrogenase
A7L45_RS03490	COG0840	transmembrane signaling receptor activity
A7L45_RS03505	COG0477	Major facilitator Superfamily
A7L45_RS03510	COG1309	transcriptional regulator
A7L45_RS03535	COG1131	(ABC) transporter
A7L45_RS03540	COG1846	Transcriptional regulator
A7L45_RS03570	COG1737	Transcriptional regulator
A7L45_RS03575	COG1027	Aspartate ammonia-lyase
A7L45_RS03585	COG1595	DNA-templated transcription, initiation
A7L45_RS03610	COG3949	Membrane
A7L45_RS03620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7L45_RS03635	COG1802	Transcriptional regulator
A7L45_RS03640	COG0281	malic enzyme
A7L45_RS03645	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A7L45_RS03660	COG3051	citrate lyase alpha subunit
A7L45_RS03665	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
A7L45_RS03665	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A7L45_RS03670	COG2828	Protein conserved in bacteria
A7L45_RS03675	COG3493	citrate carrier protein
A7L45_RS03680	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A7L45_RS03705	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A7L45_RS03725	COG1760	l-serine dehydratase
A7L45_RS03730	COG1760	l-serine dehydratase
A7L45_RS03735	COG0784	Response regulator, receiver
A7L45_RS03780	COG0156	8-amino-7-oxononanoate synthase activity
A7L45_RS03785	COG2226	methyltransferase
A7L45_RS03785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7L45_RS03785	COG0596	Alpha beta hydrolase
A7L45_RS03800	COG0745	RESPONSE REGULATOR receiver
A7L45_RS03805	COG5002	protein histidine kinase activity
A7L45_RS03815	COG0577	efflux transmembrane transporter activity
A7L45_RS03815	COG1136	(ABC) transporter
A7L45_RS03820	COG1846	Transcriptional regulator
A7L45_RS03835	COG0662	Cupin 2, conserved barrel domain protein
A7L45_RS03895	COG2207	Transcriptional regulator
A7L45_RS03900	COG0110	maltose O-acetyltransferase activity
A7L45_RS03930	COG3620	sequence-specific DNA binding
A7L45_RS03940	COG0443	Heat shock 70 kDa protein
A7L45_RS03950	COG0477	Major facilitator Superfamily
A7L45_RS03965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7L45_RS03990	COG0546	phosphoglycolate phosphatase activity
A7L45_RS04005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A7L45_RS04050	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A7L45_RS04060	COG3586	endonuclease activity
A7L45_RS04065	COG1061	Type III restriction enzyme res subunit
A7L45_RS04070	COG0494	nUDIX hydrolase
A7L45_RS04075	COG0863	Belongs to the N(4) N(6)-methyltransferase family
A7L45_RS04110	COG0135	phosphoribosylanthranilate isomerase activity
A7L45_RS04115	COG1522	sequence-specific DNA binding
A7L45_RS04115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS04135	COG1695	Transcriptional regulator
A7L45_RS04190	COG1461	Dihydroxyacetone kinase
A7L45_RS04220	COG1131	(ABC) transporter
A7L45_RS04230	COG1595	DNA-templated transcription, initiation
A7L45_RS04240	COG1704	LemA family
A7L45_RS04245	COG0583	DNA-binding transcription factor activity
A7L45_RS04250	COG2855	membrane
A7L45_RS04255	COG3220	belongs to the UPF0276 family
A7L45_RS04315	COG1063	alcohol dehydrogenase
A7L45_RS04325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7L45_RS04335	COG2031	fatty acid transporter
A7L45_RS04340	COG1607	acyl-coa hydrolase
A7L45_RS04345	COG3246	L-lysine catabolic process to acetate
A7L45_RS04360	COG0604	alcohol dehydrogenase
A7L45_RS04375	COG1193	negative regulation of DNA recombination
A7L45_RS04380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A7L45_RS04385	COG5012	cobalamin binding
A7L45_RS04390	COG0833	amino acid
A7L45_RS04395	COG1874	Beta-galactosidase
A7L45_RS04400	COG2972	Histidine kinase
A7L45_RS04410	COG4209	transmembrane transport
A7L45_RS04415	COG0395	ABC-type sugar transport system, permease component
A7L45_RS04435	COG2824	Alkylphosphonate utilization operon protein PhnA
A7L45_RS04440	COG1234	tRNA 3'-trailer cleavage
A7L45_RS04465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7L45_RS04505	COG0628	permease
A7L45_RS04510	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
A7L45_RS04510	COG3976	FMN-binding domain protein
A7L45_RS04515	COG1733	regulation of RNA biosynthetic process
A7L45_RS04520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A7L45_RS04530	COG1554	hydrolase, family 65, central catalytic
A7L45_RS04535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7L45_RS04540	COG1609	Transcriptional regulator
A7L45_RS04555	COG2182	Extracellular solute-binding protein
A7L45_RS04565	COG3833	ABC-type maltose transport systems, permease component
A7L45_RS04590	COG3012	SEC-C Motif Domain Protein
A7L45_RS04610	COG3706	GGDEF domain
A7L45_RS04615	COG0840	transmembrane signaling receptor activity
A7L45_RS04635	COG3842	ATPase activity
A7L45_RS04640	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7L45_RS04645	COG1177	transmembrane transport
A7L45_RS04655	COG2364	Membrane
A7L45_RS04660	COG0840	transmembrane signaling receptor activity
A7L45_RS04665	COG1595	DNA-templated transcription, initiation
A7L45_RS04690	COG0772	Belongs to the SEDS family
A7L45_RS04695	COG1695	Transcriptional regulator
A7L45_RS04700	COG1725	Transcriptional regulator
A7L45_RS04705	COG1131	(ABC) transporter
A7L45_RS04720	COG1131	(ABC) transporter
A7L45_RS04735	COG1349	DNA-binding transcription factor activity
A7L45_RS04740	COG0561	phosphatase activity
A7L45_RS04750	COG3583	domain protein
A7L45_RS04750	COG1621	beta-fructofuranosidase activity
A7L45_RS04750	COG5492	domain, Protein
A7L45_RS04755	COG1621	beta-fructofuranosidase activity
A7L45_RS04760	COG4585	Histidine kinase
A7L45_RS04770	COG1653	transport
A7L45_RS04775	COG1879	ABC-type sugar transport system periplasmic component
A7L45_RS04780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS04780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS04785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS04785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS04790	COG3715	PTS system
A7L45_RS04795	COG3716	PTS system mannose fructose sorbose family IID component
A7L45_RS04805	COG0840	transmembrane signaling receptor activity
A7L45_RS04820	COG3254	rhamnose metabolic process
A7L45_RS04825	COG2814	Major facilitator Superfamily
A7L45_RS04830	COG2207	Transcriptional regulator
A7L45_RS04835	COG1070	Carbohydrate kinase
A7L45_RS04840	COG4806	L-rhamnose isomerase
A7L45_RS04865	COG0436	Aminotransferase
A7L45_RS04870	COG0745	RESPONSE REGULATOR receiver
A7L45_RS04875	COG3290	protein histidine kinase activity
A7L45_RS04885	COG1136	(ABC) transporter
A7L45_RS04890	COG0577	efflux transmembrane transporter activity
A7L45_RS04895	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A7L45_RS04900	COG1191	sigma factor activity
A7L45_RS04915	COG3973	AAA domain
A7L45_RS04920	COG1349	DNA-binding transcription factor activity
A7L45_RS04925	COG0235	Class ii aldolase
A7L45_RS04930	COG1454	alcohol dehydrogenase
A7L45_RS04945	COG2814	Major facilitator Superfamily
A7L45_RS04950	COG1609	Transcriptional regulator
A7L45_RS04955	COG1069	ribulokinase activity
A7L45_RS04960	COG0235	Class ii aldolase
A7L45_RS04965	COG2160	L-arabinose isomerase activity
A7L45_RS04970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7L45_RS04980	COG0386	Belongs to the glutathione peroxidase family
A7L45_RS05000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7L45_RS05010	COG0791	NLP P60 protein
A7L45_RS05025	COG0531	amino acid
A7L45_RS05040	COG1470	cell adhesion involved in biofilm formation
A7L45_RS05045	COG0579	oxidoreductase
A7L45_RS05065	COG0778	Nitroreductase
A7L45_RS05070	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A7L45_RS05085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7L45_RS05090	COG0531	amino acid
A7L45_RS05100	COG0110	maltose O-acetyltransferase activity
A7L45_RS05115	COG2814	Major facilitator Superfamily
A7L45_RS05130	COG0697	spore germination
A7L45_RS05170	COG0824	Thioesterase
A7L45_RS05220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A7L45_RS05230	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A7L45_RS05240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A7L45_RS05255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A7L45_RS05270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7L45_RS05285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7L45_RS05295	COG2169	Transcriptional regulator
A7L45_RS05300	COG1486	melibiose metabolic process
A7L45_RS05305	COG2972	Histidine kinase
A7L45_RS05310	COG2207	Transcriptional regulator
A7L45_RS05310	COG4753	response regulator
A7L45_RS05315	COG1653	transport
A7L45_RS05320	COG1175	transmembrane transport
A7L45_RS05325	COG0395	ABC-type sugar transport system, permease component
A7L45_RS05335	COG3711	transcriptional antiterminator
A7L45_RS05340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS05340	COG2213	PTS system mannitol-specific
A7L45_RS05350	COG1063	alcohol dehydrogenase
A7L45_RS05355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A7L45_RS05370	COG1073	alpha beta
A7L45_RS05375	COG4677	pectinesterase activity
A7L45_RS05380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A7L45_RS05390	COG0395	ABC-type sugar transport system, permease component
A7L45_RS05395	COG4209	transmembrane transport
A7L45_RS05405	COG2755	lipolytic protein G-D-S-L family
A7L45_RS05410	COG2207	Transcriptional regulator
A7L45_RS05410	COG3708	Transcriptional regulator
A7L45_RS05415	COG1131	(ABC) transporter
A7L45_RS05445	COG1028	Short-chain dehydrogenase reductase Sdr
A7L45_RS05455	COG0671	phosphoesterase, PA-phosphatase related
A7L45_RS05460	COG0215	cysteine-tRNA ligase activity
A7L45_RS05470	COG1482	cell wall glycoprotein biosynthetic process
A7L45_RS05475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7L45_RS05485	COG3773	Cell wall hydrolase
A7L45_RS05490	COG0515	serine threonine protein kinase
A7L45_RS05490	COG2815	serine threonine protein kinase
A7L45_RS05495	COG0791	NLP P60 protein
A7L45_RS05505	COG1970	mechanosensitive ion channel activity
A7L45_RS05510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7L45_RS05515	COG0531	amino acid
A7L45_RS05530	COG0697	spore germination
A7L45_RS05550	COG0835	chemotaxis
A7L45_RS05550	COG0784	Response regulator, receiver
A7L45_RS05555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7L45_RS05560	COG4279	zinc finger
A7L45_RS05565	COG1132	(ABC) transporter
A7L45_RS05570	COG1132	(ABC) transporter
A7L45_RS05580	COG0840	transmembrane signaling receptor activity
A7L45_RS05585	COG0840	transmembrane signaling receptor activity
A7L45_RS05600	COG0534	Mate efflux family protein
A7L45_RS05615	COG0456	acetyltransferase
A7L45_RS05625	COG0302	gtp cyclohydrolase
A7L45_RS05630	COG0602	queuosine metabolic process
A7L45_RS05635	COG0720	synthase
A7L45_RS05640	COG1924	4 iron, 4 sulfur cluster binding
A7L45_RS05650	COG3583	domain protein
A7L45_RS05650	COG3584	3D domain protein
A7L45_RS05670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A7L45_RS05675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7L45_RS05680	COG2197	response regulator
A7L45_RS05685	COG2972	Histidine kinase
A7L45_RS05730	COG4869	propanediol catabolic process
A7L45_RS05745	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A7L45_RS05750	COG2096	Adenosyltransferase
A7L45_RS05755	COG1012	belongs to the aldehyde dehydrogenase family
A7L45_RS05760	COG4656	Part of a membrane complex involved in electron transport
A7L45_RS05780	COG0535	radical SAM domain protein
A7L45_RS05785	COG0535	radical SAM domain protein
A7L45_RS05790	COG1522	sequence-specific DNA binding
A7L45_RS05795	COG1522	sequence-specific DNA binding
A7L45_RS05800	COG0840	transmembrane signaling receptor activity
A7L45_RS05805	COG0840	transmembrane signaling receptor activity
A7L45_RS05805	COG5278	phosphoserine phosphatase activity
A7L45_RS05810	COG2186	Transcriptional regulator
A7L45_RS05815	COG2086	electron transfer activity
A7L45_RS05820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7L45_RS05825	COG0277	FAD linked oxidase domain protein
A7L45_RS05835	COG3835	regulator
A7L45_RS05850	COG1346	cytolysis
A7L45_RS05860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7L45_RS05870	COG2086	electron transfer activity
A7L45_RS05875	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7L45_RS05880	COG0277	FAD linked oxidase domain protein
A7L45_RS05885	COG1960	acyl-CoA dehydrogenase activity
A7L45_RS05890	COG1620	l-lactate permease
A7L45_RS05895	COG3875	lactate racemase activity
A7L45_RS05930	COG0535	radical SAM domain protein
A7L45_RS05935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A7L45_RS05945	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A7L45_RS05950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A7L45_RS05950	COG3608	succinylglutamate desuccinylase aspartoacylase
A7L45_RS05955	COG0521	Mo-molybdopterin cofactor biosynthetic process
A7L45_RS05965	COG0315	cyclic pyranopterin monophosphate synthase activity
A7L45_RS05980	COG1131	(ABC) transporter
A7L45_RS05990	COG3829	transcription factor binding
A7L45_RS06005	COG1120	ATPase activity
A7L45_RS06010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7L45_RS06015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7L45_RS06020	COG4607	ABC-type enterochelin transport system periplasmic component
A7L45_RS06090	COG2003	Belongs to the UPF0758 family
A7L45_RS06110	COG0326	Molecular chaperone. Has ATPase activity
A7L45_RS06150	COG1695	Transcriptional regulator
A7L45_RS06160	COG0577	efflux transmembrane transporter activity
A7L45_RS06165	COG1136	(ABC) transporter
A7L45_RS06170	COG1968	undecaprenyl-diphosphatase activity
A7L45_RS06175	COG2205	protein histidine kinase activity
A7L45_RS06180	COG0745	RESPONSE REGULATOR receiver
A7L45_RS06185	COG1959	2 iron, 2 sulfur cluster binding
A7L45_RS06195	COG0840	transmembrane signaling receptor activity
A7L45_RS06215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7L45_RS06225	COG0826	peptidase U32
A7L45_RS06230	COG0534	Mate efflux family protein
A7L45_RS06245	COG0861	Integral membrane protein TerC family
A7L45_RS06250	COG5002	protein histidine kinase activity
A7L45_RS06265	COG0129	dihydroxy-acid dehydratase activity
A7L45_RS06280	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7L45_RS06285	COG0791	NLP P60 protein
A7L45_RS06290	COG1910	domain protein
A7L45_RS06295	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7L45_RS06300	COG4149	molybdate abc transporter
A7L45_RS06305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A7L45_RS06320	COG0347	Belongs to the P(II) protein family
A7L45_RS06325	COG0347	Belongs to the P(II) protein family
A7L45_RS06380	COG0768	penicillin binding
A7L45_RS06390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7L45_RS06405	COG4656	Part of a membrane complex involved in electron transport
A7L45_RS06410	COG4658	electron transport chain
A7L45_RS06415	COG4659	FMN binding
A7L45_RS06420	COG4660	Part of a membrane complex involved in electron transport
A7L45_RS06425	COG4657	Part of a membrane complex involved in electron transport
A7L45_RS06430	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
A7L45_RS06430	COG2878	Part of a membrane complex involved in electron transport
A7L45_RS06435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7L45_RS06440	COG2078	PFAM AMMECR1 domain protein
A7L45_RS06440	COG3885	ferrous iron binding
A7L45_RS06450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7L45_RS06460	COG0778	Nitroreductase
A7L45_RS06470	COG0598	Magnesium transport protein CorA
A7L45_RS06485	COG2733	membrane
A7L45_RS06490	COG2733	membrane
A7L45_RS06505	COG0038	chloride channel
A7L45_RS06515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A7L45_RS06535	COG0494	nUDIX hydrolase
A7L45_RS06545	COG3620	sequence-specific DNA binding
A7L45_RS06575	COG4536	flavin adenine dinucleotide binding
A7L45_RS06585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7L45_RS06590	COG1609	Transcriptional regulator
A7L45_RS06600	COG1175	transmembrane transport
A7L45_RS06605	COG0395	ABC-type sugar transport system, permease component
A7L45_RS06610	COG2942	2-epimerase
A7L45_RS06615	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
A7L45_RS06620	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
A7L45_RS06635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A7L45_RS06635	COG2755	lipolytic protein G-D-S-L family
A7L45_RS06640	COG2723	6-phospho-beta-galactosidase activity
A7L45_RS06645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS06645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS06650	COG0477	Major facilitator Superfamily
A7L45_RS06660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A7L45_RS06685	COG0351	phosphomethylpyrimidine kinase
A7L45_RS06685	COG0352	thiamine-phosphate diphosphorylase activity
A7L45_RS06695	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A7L45_RS06705	COG0205	6-phosphofructokinase activity
A7L45_RS06730	COG1904	glucuronate isomerase
A7L45_RS06735	COG1609	Transcriptional regulator
A7L45_RS06740	COG0246	Mannitol dehydrogenase
A7L45_RS06745	COG0800	Aldolase
A7L45_RS06755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS06760	COG0246	Mannitol dehydrogenase
A7L45_RS06765	COG2721	sulfolactate sulfo-lyase activity
A7L45_RS06775	COG2211	Major facilitator Superfamily
A7L45_RS06790	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A7L45_RS06805	COG0542	response to heat
A7L45_RS06810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A7L45_RS06825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A7L45_RS06835	COG1131	(ABC) transporter
A7L45_RS06845	COG0390	transport system, permease component
A7L45_RS06850	COG4619	ABC transporter
A7L45_RS06855	COG3457	Alanine racemase
A7L45_RS06860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7L45_RS06870	COG0515	serine threonine protein kinase
A7L45_RS06880	COG0628	permease
A7L45_RS06890	COG3384	dioxygenase
A7L45_RS06900	COG2169	Transcriptional regulator
A7L45_RS06905	COG2199	diguanylate cyclase activity
A7L45_RS06905	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A7L45_RS06920	COG0527	aspartate kinase activity
A7L45_RS06925	COG0460	homoserine dehydrogenase
A7L45_RS06935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A7L45_RS06935	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A7L45_RS06940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS06940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS06950	COG3715	PTS system
A7L45_RS06955	COG3716	PTS system mannose fructose sorbose family IID component
A7L45_RS06970	COG0646	methionine synthase
A7L45_RS06970	COG1410	methionine synthase
A7L45_RS06980	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A7L45_RS06990	COG0460	homoserine dehydrogenase
A7L45_RS06995	COG0463	Glycosyl transferase, family 2
A7L45_RS07010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A7L45_RS07015	COG2205	protein histidine kinase activity
A7L45_RS07015	COG2770	Histidine kinase
A7L45_RS07020	COG0745	RESPONSE REGULATOR receiver
A7L45_RS07035	COG1664	Polymer-forming cytoskeletal
A7L45_RS07040	COG0789	Transcriptional regulator
A7L45_RS07045	COG1301	dicarboxylic acid transport
A7L45_RS07070	COG3402	PFAM membrane-flanked domain
A7L45_RS07075	COG3428	Bacterial PH domain
A7L45_RS07115	COG1131	(ABC) transporter
A7L45_RS07125	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A7L45_RS07130	COG5002	protein histidine kinase activity
A7L45_RS07145	COG0745	RESPONSE REGULATOR receiver
A7L45_RS07150	COG3850	Histidine kinase
A7L45_RS07150	COG5002	protein histidine kinase activity
A7L45_RS07165	COG2271	Major facilitator Superfamily
A7L45_RS07175	COG0791	NLP P60 protein
A7L45_RS07180	COG5002	protein histidine kinase activity
A7L45_RS07185	COG0768	penicillin binding
A7L45_RS07195	COG0861	Integral membrane protein TerC family
A7L45_RS07200	COG0537	adenosine 5'-monophosphoramidase activity
A7L45_RS07205	COG1312	Catalyzes the dehydration of D-mannonate
A7L45_RS07210	COG0745	RESPONSE REGULATOR receiver
A7L45_RS07215	COG2205	protein histidine kinase activity
A7L45_RS07220	COG1136	(ABC) transporter
A7L45_RS07225	COG0577	efflux transmembrane transporter activity
A7L45_RS07245	COG0745	RESPONSE REGULATOR receiver
A7L45_RS07250	COG2205	protein histidine kinase activity
A7L45_RS07260	COG2814	Major facilitator Superfamily
A7L45_RS07285	COG2226	methyltransferase
A7L45_RS07290	COG1476	TRANSCRIPTIONal
A7L45_RS07320	COG0840	transmembrane signaling receptor activity
A7L45_RS07325	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A7L45_RS07335	COG1396	sequence-specific DNA binding
A7L45_RS07340	COG0840	transmembrane signaling receptor activity
A7L45_RS07345	COG0129	dihydroxy-acid dehydratase activity
A7L45_RS07350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS07355	COG2610	gluconate transmembrane transporter activity
A7L45_RS07365	COG3279	Response regulator of the LytR AlgR family
A7L45_RS07375	COG0596	Alpha beta hydrolase
A7L45_RS07400	COG0346	lactoylglutathione lyase activity
A7L45_RS07415	COG2267	carboxylic ester hydrolase activity
A7L45_RS07420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7L45_RS07430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7L45_RS07430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7L45_RS07430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS07435	COG1105	Belongs to the carbohydrate kinase PfkB family
A7L45_RS07445	COG0534	Mate efflux family protein
A7L45_RS07460	COG5278	phosphoserine phosphatase activity
A7L45_RS07460	COG0840	transmembrane signaling receptor activity
A7L45_RS07485	COG4585	Histidine kinase
A7L45_RS07490	COG1131	(ABC) transporter
A7L45_RS07510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7L45_RS07535	COG0768	penicillin binding
A7L45_RS07545	COG0840	transmembrane signaling receptor activity
A7L45_RS07560	COG1174	glycine betaine transport
A7L45_RS07640	COG0745	RESPONSE REGULATOR receiver
A7L45_RS07645	COG2205	protein histidine kinase activity
A7L45_RS07645	COG2770	Histidine kinase
A7L45_RS07655	COG0840	transmembrane signaling receptor activity
A7L45_RS07680	COG1136	(ABC) transporter
A7L45_RS07685	COG0577	efflux transmembrane transporter activity
A7L45_RS07690	COG0745	RESPONSE REGULATOR receiver
A7L45_RS07695	COG2205	protein histidine kinase activity
A7L45_RS07705	COG1476	TRANSCRIPTIONal
A7L45_RS07720	COG1309	transcriptional regulator
A7L45_RS07750	COG5002	protein histidine kinase activity
A7L45_RS07755	COG0778	Nitroreductase
A7L45_RS07780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7L45_RS07785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A7L45_RS07790	COG1882	Formate acetyltransferase
A7L45_RS07795	COG1349	DNA-binding transcription factor activity
A7L45_RS07805	COG4804	nuclease activity
A7L45_RS07810	COG1061	Type III restriction enzyme res subunit
A7L45_RS07840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A7L45_RS07870	COG2801	Transposase and inactivated derivatives
A7L45_RS07885	COG4974	Belongs to the 'phage' integrase family
A7L45_RS07920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A7L45_RS07925	COG0732	type I restriction modification DNA specificity domain
A7L45_RS07930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A7L45_RS07945	COG0791	NLP P60 protein
A7L45_RS07950	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A7L45_RS07955	COG1263	PTS System
A7L45_RS07955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS07975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7L45_RS07980	COG0653	protein targeting
A7L45_RS07990	COG1396	sequence-specific DNA binding
A7L45_RS08055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7L45_RS08090	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A7L45_RS08120	COG3052	prosthetic group binding
A7L45_RS08125	COG2301	Belongs to the HpcH HpaI aldolase family
A7L45_RS08130	COG3051	citrate lyase alpha subunit
A7L45_RS08150	COG0833	amino acid
A7L45_RS08160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A7L45_RS08190	COG1979	alcohol dehydrogenase
A7L45_RS08215	COG4948	Mandelate Racemase Muconate Lactonizing
A7L45_RS08235	COG0386	Belongs to the glutathione peroxidase family
A7L45_RS08290	COG0024	Methionine aminopeptidase
A7L45_RS08295	COG0789	Transcriptional regulator
A7L45_RS08390	COG1131	(ABC) transporter
A7L45_RS08410	COG0745	RESPONSE REGULATOR receiver
A7L45_RS08415	COG5002	protein histidine kinase activity
A7L45_RS08430	COG3647	Membrane
A7L45_RS08455	COG0110	maltose O-acetyltransferase activity
A7L45_RS08460	COG0426	domain, Protein
A7L45_RS08460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7L45_RS08470	COG1733	regulation of RNA biosynthetic process
A7L45_RS08490	COG1131	(ABC) transporter
A7L45_RS08495	COG2205	protein histidine kinase activity
A7L45_RS08500	COG0745	RESPONSE REGULATOR receiver
A7L45_RS08510	COG1695	Transcriptional regulator
A7L45_RS08525	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7L45_RS08535	COG0210	DNA helicase
A7L45_RS08545	COG3012	SEC-C Motif Domain Protein
A7L45_RS08550	COG1131	(ABC) transporter
A7L45_RS08570	COG1129	ABC transporter
A7L45_RS08580	COG0367	asparagine synthase
A7L45_RS08585	COG0395	ABC-type sugar transport system, permease component
A7L45_RS08600	COG0789	Transcriptional regulator
A7L45_RS08610	COG0745	RESPONSE REGULATOR receiver
A7L45_RS08615	COG2205	protein histidine kinase activity
A7L45_RS08620	COG1136	(ABC) transporter
A7L45_RS08630	COG4129	membrane
A7L45_RS08640	COG2755	lipolytic protein G-D-S-L family
A7L45_RS08645	COG3401	FG-GAP repeat protein
A7L45_RS08645	COG2755	lipolytic protein G-D-S-L family
A7L45_RS08650	COG3401	FG-GAP repeat protein
A7L45_RS08655	COG1917	Cupin 2, conserved barrel domain protein
A7L45_RS08655	COG2207	Transcriptional regulator
A7L45_RS08660	COG4209	transmembrane transport
A7L45_RS08665	COG0395	ABC-type sugar transport system, permease component
A7L45_RS08670	COG1653	transport
A7L45_RS08675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A7L45_RS08680	COG5426	von Willebrand factor, type A
A7L45_RS08685	COG2755	lipolytic protein G-D-S-L family
A7L45_RS08690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7L45_RS08695	COG0765	amino acid transport
A7L45_RS08710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A7L45_RS08715	COG3775	system Galactitol-specific IIC component
A7L45_RS08720	COG3414	Phosphotransferase system galactitol-specific IIB component
A7L45_RS08730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A7L45_RS08730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A7L45_RS08740	COG0726	polysaccharide deacetylase
A7L45_RS08745	COG3507	Belongs to the glycosyl hydrolase 43 family
A7L45_RS08800	COG3345	alpha-galactosidase
A7L45_RS08810	COG4753	response regulator
A7L45_RS08810	COG2207	Transcriptional regulator
A7L45_RS08815	COG2972	Histidine kinase
A7L45_RS08820	COG2207	Transcriptional regulator
A7L45_RS08820	COG4753	response regulator
A7L45_RS08830	COG4209	transmembrane transport
A7L45_RS08835	COG0395	ABC-type sugar transport system, permease component
A7L45_RS08855	COG1472	Belongs to the glycosyl hydrolase 3 family
A7L45_RS08870	COG1136	(ABC) transporter
A7L45_RS08870	COG0577	efflux transmembrane transporter activity
A7L45_RS08875	COG0443	Heat shock 70 kDa protein
A7L45_RS08885	COG0484	heat shock protein binding
A7L45_RS08895	COG1113	amino acid transport
A7L45_RS08925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A7L45_RS08930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7L45_RS08940	COG2205	protein histidine kinase activity
A7L45_RS08940	COG0784	Response regulator, receiver
A7L45_RS08950	COG1854	S-ribosylhomocysteine lyase activity
A7L45_RS08965	COG1959	2 iron, 2 sulfur cluster binding
A7L45_RS08980	COG3866	Pectate lyase
A7L45_RS08985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A7L45_RS08990	COG3344	reverse transcriptase
A7L45_RS09005	COG1164	Oligoendopeptidase f
A7L45_RS09015	COG1131	(ABC) transporter
A7L45_RS09025	COG0288	reversible hydration of carbon dioxide
A7L45_RS09030	COG2390	Transcriptional regulator
A7L45_RS09035	COG0295	cytidine deaminase activity
A7L45_RS09040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A7L45_RS09045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7L45_RS09050	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A7L45_RS09055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A7L45_RS09065	COG0840	transmembrane signaling receptor activity
A7L45_RS09080	COG1114	Component of the transport system for branched-chain amino acids
A7L45_RS09090	COG2201	protein-glutamate methylesterase activity
A7L45_RS09115	COG1744	ABC transporter substrate-binding protein PnrA-like
A7L45_RS09120	COG3845	ABC transporter
A7L45_RS09125	COG4603	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS09130	COG1079	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS09135	COG1609	Transcriptional regulator
A7L45_RS09155	COG0604	alcohol dehydrogenase
A7L45_RS09180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7L45_RS09205	COG0737	Belongs to the 5'-nucleotidase family
A7L45_RS09215	COG2333	competence protein COMEC
A7L45_RS09215	COG0658	competence protein
A7L45_RS09230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS09235	COG3718	enzyme involved in inositol metabolism
A7L45_RS09245	COG0673	inositol 2-dehydrogenase activity
A7L45_RS09255	COG1349	DNA-binding transcription factor activity
A7L45_RS09260	COG2814	Major facilitator Superfamily
A7L45_RS09265	COG2190	(PTS) system
A7L45_RS09275	COG1960	acyl-CoA dehydrogenase activity
A7L45_RS09280	COG1024	Enoyl-CoA hydratase
A7L45_RS09295	COG1968	undecaprenyl-diphosphatase activity
A7L45_RS09300	COG4632	Exopolysaccharide biosynthesis protein
A7L45_RS09300	COG5434	Belongs to the glycosyl hydrolase 28 family
A7L45_RS09310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7L45_RS09320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7L45_RS09335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7L45_RS09340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7L45_RS09345	COG1696	Membrane protein involved in D-alanine export
A7L45_RS09370	COG0840	transmembrane signaling receptor activity
A7L45_RS09375	COG4555	ABC transporter
A7L45_RS09380	COG1668	transmembrane transport
A7L45_RS09385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7L45_RS09390	COG0666	response to abiotic stimulus
A7L45_RS09400	COG1132	(ABC) transporter
A7L45_RS09405	COG1132	(ABC) transporter
A7L45_RS09410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7L45_RS09420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7L45_RS09445	COG3250	beta-galactosidase activity
A7L45_RS09450	COG4555	ABC transporter
A7L45_RS09465	COG0346	lactoylglutathione lyase activity
A7L45_RS09480	COG2201	protein-glutamate methylesterase activity
A7L45_RS09490	COG0840	transmembrane signaling receptor activity
A7L45_RS09495	COG0840	transmembrane signaling receptor activity
A7L45_RS09500	COG0643	Histidine kinase
A7L45_RS09500	COG2198	Histidine kinase
A7L45_RS09505	COG0835	chemotaxis
A7L45_RS09510	COG0840	transmembrane signaling receptor activity
A7L45_RS09520	COG2201	protein-glutamate methylesterase activity
A7L45_RS09525	COG0028	Belongs to the TPP enzyme family
A7L45_RS09535	COG0372	Belongs to the citrate synthase family
A7L45_RS09540	COG1408	metallophosphoesterase
A7L45_RS09555	COG0531	amino acid
A7L45_RS09565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7L45_RS09580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7L45_RS09595	COG5002	protein histidine kinase activity
A7L45_RS09600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A7L45_RS09605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7L45_RS09610	COG3459	Glycosyltransferase 36 associated
A7L45_RS09615	COG1609	Transcriptional regulator
A7L45_RS09630	COG0395	ABC-type sugar transport system, permease component
A7L45_RS09640	COG3901	Regulator of nitric oxide reductase transcription
A7L45_RS09640	COG0348	domain, Protein
A7L45_RS09660	COG0484	heat shock protein binding
A7L45_RS09840	COG2801	Transposase and inactivated derivatives
A7L45_RS10070	COG1522	sequence-specific DNA binding
A7L45_RS10080	COG4335	DNA alkylation repair
A7L45_RS10090	COG2323	membrane
A7L45_RS10100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7L45_RS10120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7L45_RS10130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A7L45_RS10135	COG0386	Belongs to the glutathione peroxidase family
A7L45_RS10140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7L45_RS10145	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7L45_RS10150	COG1216	Glycosyl transferase, family 2
A7L45_RS10155	COG1902	pentaerythritol trinitrate reductase activity
A7L45_RS10160	COG0534	Mate efflux family protein
A7L45_RS10170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7L45_RS10175	COG3344	reverse transcriptase
A7L45_RS10190	COG3830	Belongs to the UPF0237 family
A7L45_RS10195	COG2848	UPF0210 protein
A7L45_RS10200	COG0697	spore germination
A7L45_RS10205	COG0531	amino acid
A7L45_RS10250	COG2201	protein-glutamate methylesterase activity
A7L45_RS10270	COG0559	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS10295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7L45_RS10300	COG1473	amidohydrolase
A7L45_RS10305	COG0626	cystathionine gamma-synthase activity
A7L45_RS10310	COG1126	abc transporter atp-binding protein
A7L45_RS10315	COG0765	amino acid transport
A7L45_RS10320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7L45_RS10325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7L45_RS10330	COG0004	ammonium transporteR
A7L45_RS10340	COG0004	ammonium transporteR
A7L45_RS10345	COG0004	ammonium transporteR
A7L45_RS10350	COG0347	Belongs to the P(II) protein family
A7L45_RS10355	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7L45_RS10365	COG0765	amino acid transport
A7L45_RS10370	COG0765	amino acid transport
A7L45_RS10375	COG1126	abc transporter atp-binding protein
A7L45_RS10380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7L45_RS10385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7L45_RS10385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7L45_RS10400	COG0067	glutamate synthase
A7L45_RS10400	COG0070	glutamate synthase
A7L45_RS10400	COG0069	glutamate synthase activity
A7L45_RS10420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7L45_RS10425	COG0529	Catalyzes the synthesis of activated sulfate
A7L45_RS10430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7L45_RS10440	COG0175	sulfate reduction
A7L45_RS10445	COG2895	sulfate adenylyltransferase (ATP) activity
A7L45_RS10460	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A7L45_RS10470	COG1609	Transcriptional regulator
A7L45_RS10475	COG0248	Ppx GppA phosphatase
A7L45_RS10485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A7L45_RS10510	COG1606	tRNA processing
A7L45_RS10515	COG3875	lactate racemase activity
A7L45_RS10520	COG0436	Aminotransferase
A7L45_RS10525	COG0673	inositol 2-dehydrogenase activity
A7L45_RS10540	COG0673	inositol 2-dehydrogenase activity
A7L45_RS10555	COG0726	polysaccharide deacetylase
A7L45_RS10565	COG1696	Membrane protein involved in D-alanine export
A7L45_RS10570	COG2210	Belongs to the sulfur carrier protein TusA family
A7L45_RS10580	COG2207	Transcriptional regulator
A7L45_RS10590	COG1175	transmembrane transport
A7L45_RS10595	COG0395	ABC-type sugar transport system, permease component
A7L45_RS10605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7L45_RS10610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS10635	COG0697	spore germination
A7L45_RS10640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7L45_RS10650	COG3842	ATPase activity
A7L45_RS10655	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A7L45_RS10660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A7L45_RS10665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A7L45_RS10670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7L45_RS10675	COG0131	Imidazoleglycerol-phosphate dehydratase
A7L45_RS10680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A7L45_RS10695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A7L45_RS10705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7L45_RS10720	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7L45_RS10725	COG0579	oxidoreductase
A7L45_RS10735	COG0406	alpha-ribazole phosphatase activity
A7L45_RS10740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A7L45_RS10745	COG0287	Prephenate dehydrogenase
A7L45_RS10750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A7L45_RS10755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A7L45_RS10760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A7L45_RS10765	COG1605	Chorismate mutase
A7L45_RS10765	COG0077	Prephenate dehydratase
A7L45_RS10770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A7L45_RS10780	COG0159	tryptophan synthase activity
A7L45_RS10790	COG0135	phosphoribosylanthranilate isomerase activity
A7L45_RS10795	COG0134	indole-3-glycerol-phosphate synthase activity
A7L45_RS10805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7L45_RS10805	COG0512	Glutamine amidotransferase of anthranilate synthase
A7L45_RS10815	COG1461	Dihydroxyacetone kinase
A7L45_RS10835	COG2703	oxygen carrier activity
A7L45_RS10855	COG0710	3-dehydroquinate dehydratase activity
A7L45_RS10860	COG0840	transmembrane signaling receptor activity
A7L45_RS10865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A7L45_RS10885	COG4294	response to UV
A7L45_RS10890	COG5002	protein histidine kinase activity
A7L45_RS10895	COG0745	RESPONSE REGULATOR receiver
A7L45_RS10920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7L45_RS10960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7L45_RS10980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7L45_RS10985	COG0765	amino acid transport
A7L45_RS10990	COG1126	abc transporter atp-binding protein
A7L45_RS10995	COG0137	argininosuccinate synthase activity
A7L45_RS11000	COG0165	Argininosuccinate lyase
A7L45_RS11005	COG1752	Esterase of the alpha-beta hydrolase superfamily
A7L45_RS11010	COG0456	acetyltransferase
A7L45_RS11030	COG0494	nUDIX hydrolase
A7L45_RS11035	COG1136	(ABC) transporter
A7L45_RS11045	COG0745	RESPONSE REGULATOR receiver
A7L45_RS11050	COG2205	protein histidine kinase activity
A7L45_RS11050	COG3292	Two component regulator propeller
A7L45_RS11050	COG0745	RESPONSE REGULATOR receiver
A7L45_RS11065	COG3681	Belongs to the UPF0597 family
A7L45_RS11070	COG3949	Membrane
A7L45_RS11100	COG0702	epimerase
A7L45_RS11105	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A7L45_RS11110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7L45_RS11120	COG4974	Belongs to the 'phage' integrase family
A7L45_RS11130	COG2801	Transposase and inactivated derivatives
A7L45_RS11135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7L45_RS11140	COG2155	Conserved Protein
A7L45_RS11145	COG4978	Transcriptional regulator
A7L45_RS11145	COG0789	Transcriptional regulator
A7L45_RS11155	COG1132	(ABC) transporter
A7L45_RS11160	COG0825	malonyl-CoA metabolic process
A7L45_RS11165	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A7L45_RS11170	COG0439	Biotin carboxylase
A7L45_RS11175	COG0511	ligase activity, forming carbon-carbon bonds
A7L45_RS11180	COG2070	2-Nitropropane dioxygenase
A7L45_RS11185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7L45_RS11220	COG3279	Response regulator of the LytR AlgR family
A7L45_RS11235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A7L45_RS11240	COG0371	Dehydrogenase
A7L45_RS11350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7L45_RS11375	COG2226	methyltransferase
A7L45_RS11380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A7L45_RS11405	COG1773	rubredoxin
A7L45_RS11430	COG5002	protein histidine kinase activity
A7L45_RS11435	COG0745	RESPONSE REGULATOR receiver
A7L45_RS11450	COG3069	C4-dicarboxylate transmembrane transporter activity
A7L45_RS11500	COG4895	conserved protein (DUF2196)
A7L45_RS11510	COG1523	belongs to the glycosyl hydrolase 13 family
A7L45_RS11545	COG1940	carbohydrate kinase activity
A7L45_RS11570	COG1523	belongs to the glycosyl hydrolase 13 family
A7L45_RS11580	COG1392	Phosphate transport regulator
A7L45_RS11585	COG0306	phosphate transporter
A7L45_RS11590	COG0813	purine-nucleoside phosphorylase activity
A7L45_RS11625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7L45_RS11635	COG1160	GTP binding
A7L45_RS11645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7L45_RS11650	COG0704	Plays a role in the regulation of phosphate uptake
A7L45_RS11655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7L45_RS11660	COG0581	inorganic phosphate transmembrane transporter activity
A7L45_RS11665	COG0573	inorganic phosphate transmembrane transporter activity
A7L45_RS11670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7L45_RS11675	COG5002	protein histidine kinase activity
A7L45_RS11680	COG0745	RESPONSE REGULATOR receiver
A7L45_RS11685	COG1496	oxidoreductase activity
A7L45_RS11690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A7L45_RS11695	COG1873	PFAM PRC-barrel domain
A7L45_RS11700	COG1191	sigma factor activity
A7L45_RS11710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7L45_RS11715	COG0849	cell division
A7L45_RS11735	COG0572	uridine kinase
A7L45_RS11740	COG0826	peptidase U32
A7L45_RS11745	COG4122	O-methyltransferase activity
A7L45_RS11750	COG1217	gtp-binding protein TYPA
A7L45_RS11755	COG0735	belongs to the Fur family
A7L45_RS11780	COG0628	permease
A7L45_RS11790	COG1472	Belongs to the glycosyl hydrolase 3 family
A7L45_RS11795	COG0822	iron-sulfur transferase activity
A7L45_RS11800	COG0482	sulfurtransferase activity
A7L45_RS11805	COG0822	iron-sulfur transferase activity
A7L45_RS11815	COG1959	2 iron, 2 sulfur cluster binding
A7L45_RS11825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7L45_RS11830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7L45_RS11835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7L45_RS11840	COG2966	Psort location CytoplasmicMembrane, score
A7L45_RS11850	COG1937	Protein conserved in bacteria
A7L45_RS11855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A7L45_RS11860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7L45_RS11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7L45_RS11875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7L45_RS11880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7L45_RS11890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7L45_RS11895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7L45_RS11915	COG1862	Preprotein translocase
A7L45_RS11935	COG0632	four-way junction helicase activity
A7L45_RS11950	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A7L45_RS11955	COG1533	DNA photolyase activity
A7L45_RS11965	COG2226	methyltransferase
A7L45_RS11970	COG0628	permease
A7L45_RS11985	COG0513	Belongs to the DEAD box helicase family
A7L45_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
A7L45_RS12015	COG1959	2 iron, 2 sulfur cluster binding
A7L45_RS12050	COG1739	Uncharacterized protein family UPF0029
A7L45_RS12060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7L45_RS12075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7L45_RS12080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A7L45_RS12100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7L45_RS12110	COG1191	sigma factor activity
A7L45_RS12115	COG2172	sigma factor antagonist activity
A7L45_RS12125	COG0427	acetyl-CoA hydrolase
A7L45_RS12140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7L45_RS12145	COG0531	amino acid
A7L45_RS12150	COG1454	alcohol dehydrogenase
A7L45_RS12155	COG1012	belongs to the aldehyde dehydrogenase family
A7L45_RS12160	COG0427	acetyl-CoA hydrolase
A7L45_RS12165	COG0697	spore germination
A7L45_RS12170	COG0427	acetyl-CoA hydrolase
A7L45_RS12215	COG3404	Formiminotransferase-cyclodeaminase
A7L45_RS12230	COG0728	peptidoglycan biosynthetic process
A7L45_RS12235	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS12240	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A7L45_RS12280	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS12300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7L45_RS12305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7L45_RS12310	COG1083	cytidylyl-transferase
A7L45_RS12325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7L45_RS12335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7L45_RS12340	COG2089	acid synthase
A7L45_RS12380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7L45_RS12385	COG1982	Orn Lys Arg decarboxylase major
A7L45_RS12390	COG1683	Conserved Protein
A7L45_RS12400	COG0826	peptidase U32
A7L45_RS12420	COG0471	metal ion transport
A7L45_RS12425	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A7L45_RS12425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A7L45_RS12435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7L45_RS12465	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
A7L45_RS12480	COG0583	DNA-binding transcription factor activity
A7L45_RS12490	COG0708	Exodeoxyribonuclease III
A7L45_RS12500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7L45_RS12505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7L45_RS12510	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS12515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7L45_RS12520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7L45_RS12530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7L45_RS12545	COG3835	regulator
A7L45_RS12550	COG1929	Belongs to the glycerate kinase type-1 family
A7L45_RS12555	COG2610	gluconate transmembrane transporter activity
A7L45_RS12565	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7L45_RS12600	COG0840	transmembrane signaling receptor activity
A7L45_RS12620	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7L45_RS12635	COG3620	sequence-specific DNA binding
A7L45_RS12645	COG0531	amino acid
A7L45_RS12655	COG1199	ATP-dependent helicase activity
A7L45_RS12660	COG4974	Belongs to the 'phage' integrase family
A7L45_RS12710	COG1113	amino acid transport
A7L45_RS12730	COG2205	protein histidine kinase activity
A7L45_RS12735	COG0745	RESPONSE REGULATOR receiver
A7L45_RS12740	COG1725	Transcriptional regulator
A7L45_RS12745	COG1131	(ABC) transporter
A7L45_RS12755	COG2207	Transcriptional regulator
A7L45_RS12755	COG3708	Transcriptional regulator
A7L45_RS12765	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7L45_RS12785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7L45_RS12800	COG4106	trans-aconitate 2-methyltransferase activity
A7L45_RS12805	COG0412	Dienelactone hydrolase
A7L45_RS12820	COG0789	Transcriptional regulator
A7L45_RS12840	COG0009	L-threonylcarbamoyladenylate synthase
A7L45_RS12860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7L45_RS12865	COG2364	Membrane
A7L45_RS12880	COG0628	permease
A7L45_RS12895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7L45_RS12900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7L45_RS12930	COG1376	ErfK ybiS ycfS ynhG family protein
A7L45_RS12935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A7L45_RS12935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A7L45_RS12940	COG0726	polysaccharide deacetylase
A7L45_RS12950	COG4585	Histidine kinase
A7L45_RS12955	COG0577	efflux transmembrane transporter activity
A7L45_RS12960	COG1136	(ABC) transporter
A7L45_RS12990	COG0726	polysaccharide deacetylase
A7L45_RS12995	COG4286	Uncharacterised protein family (UPF0160)
A7L45_RS13000	COG1923	regulation of RNA biosynthetic process
A7L45_RS13005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A7L45_RS13010	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A7L45_RS13040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A7L45_RS13045	COG2081	HI0933 family
A7L45_RS13050	COG1737	Transcriptional regulator
A7L45_RS13055	COG1187	pseudouridine synthase activity
A7L45_RS13080	COG4974	Belongs to the 'phage' integrase family
A7L45_RS13100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A7L45_RS13105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A7L45_RS13110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7L45_RS13115	COG1674	ftsk spoiiie
A7L45_RS13120	COG0740	serine-type endopeptidase activity
A7L45_RS13125	COG0527	aspartate kinase activity
A7L45_RS13135	COG0612	Peptidase, M16
A7L45_RS13140	COG1185	polyribonucleotide nucleotidyltransferase activity
A7L45_RS13150	COG0196	riboflavin kinase activity
A7L45_RS13155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7L45_RS13165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A7L45_RS13175	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A7L45_RS13180	COG0195	Participates in both transcription termination and antitermination
A7L45_RS13195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A7L45_RS13200	COG0750	zinc metalloprotease
A7L45_RS13205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A7L45_RS13210	COG4589	Belongs to the CDS family
A7L45_RS13220	COG0233	cytoplasmic translational termination
A7L45_RS13235	COG0052	Belongs to the universal ribosomal protein uS2 family
A7L45_RS13245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7L45_RS13250	COG0758	DNA mediated transformation
A7L45_RS13255	COG0606	chelatase, subunit chli
A7L45_RS13265	COG1984	allophanate hydrolase subunit 2
A7L45_RS13270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7L45_RS13275	COG1914	H( )-stimulated, divalent metal cation uptake system
A7L45_RS13280	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7L45_RS13285	COG0786	glutamate:sodium symporter activity
A7L45_RS13300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7L45_RS13305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7L45_RS13315	COG0336	Belongs to the RNA methyltransferase TrmD family
A7L45_RS13335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7L45_RS13345	COG0552	protein localization to endoplasmic reticulum
A7L45_RS13365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7L45_RS13370	COG0416	fatty acid biosynthetic process
A7L45_RS13375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A7L45_RS13390	COG0280	phosphate acetyltransferase
A7L45_RS13395	COG1323	Belongs to the UPF0348 family
A7L45_RS13400	COG3314	Sporulation integral membrane protein YlbJ
A7L45_RS13410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A7L45_RS13415	COG0742	ribosomal rna small subunit methyltransferase
A7L45_RS13420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A7L45_RS13425	COG1461	Dihydroxyacetone kinase
A7L45_RS13445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7L45_RS13455	COG0515	serine threonine protein kinase
A7L45_RS13455	COG2815	serine threonine protein kinase
A7L45_RS13460	COG0631	protein serine/threonine phosphatase activity
A7L45_RS13470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7L45_RS13470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7L45_RS13475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A7L45_RS13485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7L45_RS13490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7L45_RS13505	COG2052	Domain of unknown function (DUF370)
A7L45_RS13510	COG1561	YicC-like family, N-terminal region
A7L45_RS13515	COG0436	Aminotransferase
A7L45_RS13520	COG2252	PERMEase
A7L45_RS13540	COG1846	Transcriptional regulator
A7L45_RS13550	COG0445	tRNA wobble uridine modification
A7L45_RS13560	COG0542	response to heat
A7L45_RS13570	COG1686	Belongs to the peptidase S11 family
A7L45_RS13580	COG3874	Sporulation protein YtfJ
A7L45_RS13585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A7L45_RS13590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A7L45_RS13595	COG1686	Belongs to the peptidase S11 family
A7L45_RS13600	COG4974	Belongs to the 'phage' integrase family
A7L45_RS13635	COG0745	RESPONSE REGULATOR receiver
A7L45_RS13640	COG0750	zinc metalloprotease
A7L45_RS13645	COG0497	DNA recombination
A7L45_RS13650	COG1438	arginine binding
A7L45_RS13655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7L45_RS13660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A7L45_RS13665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A7L45_RS13680	COG1570	exodeoxyribonuclease VII activity
A7L45_RS13690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7L45_RS13735	COG3854	ATPases associated with a variety of cellular activities
A7L45_RS13780	COG1459	type II secretion system
A7L45_RS13825	COG0658	competence protein
A7L45_RS13825	COG2333	competence protein COMEC
A7L45_RS14055	COG0358	DNA primase activity
A7L45_RS14060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A7L45_RS14085	COG0629	single-stranded DNA binding
A7L45_RS14115	COG2002	toxin-antitoxin pair type II binding
A7L45_RS14145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7L45_RS14155	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A7L45_RS14160	COG2226	methyltransferase
A7L45_RS14165	COG1335	isochorismatase
A7L45_RS14175	COG1522	sequence-specific DNA binding
A7L45_RS14180	COG0116	Belongs to the methyltransferase superfamily
A7L45_RS14190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A7L45_RS14195	COG0564	pseudouridine synthase activity
A7L45_RS14200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A7L45_RS14205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7L45_RS14210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A7L45_RS14215	COG3599	regulation of cell shape
A7L45_RS14220	COG2302	S4 RNA-binding domain
A7L45_RS14230	COG1799	cell septum assembly
A7L45_RS14235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7L45_RS14255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7L45_RS14260	COG0772	Belongs to the SEDS family
A7L45_RS14270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7L45_RS14280	COG0768	penicillin binding
A7L45_RS14300	COG0012	GTP binding
A7L45_RS14305	COG1067	ATP-dependent peptidase activity
A7L45_RS14315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7L45_RS14335	COG4786	Flagellar basal body rod
A7L45_RS14345	COG1191	sigma factor activity
A7L45_RS14355	COG0455	bacterial-type flagellum organization
A7L45_RS14360	COG1419	protein localization to endoplasmic reticulum
A7L45_RS14365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7L45_RS14370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7L45_RS14380	COG1338	Plays a role in the flagellum-specific transport system
A7L45_RS14405	COG1582	Flagellar protein (FlbD)
A7L45_RS14435	COG1157	protein secretion by the type III secretion system
A7L45_RS14445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7L45_RS14450	COG1766	The M ring may be actively involved in energy transduction
A7L45_RS14455	COG1677	Flagellar hook-basal body complex protein FliE
A7L45_RS14465	COG1815	bacterial-type flagellum-dependent cell motility
A7L45_RS14490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7L45_RS14510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7L45_RS14515	COG1088	dTDP-glucose 4,6-dehydratase activity
A7L45_RS14530	COG1086	Polysaccharide biosynthesis protein
A7L45_RS14535	COG2089	acid synthase
A7L45_RS14545	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
A7L45_RS14575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7L45_RS14585	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A7L45_RS14590	COG1516	flagellar protein fliS
A7L45_RS14600	COG1334	flagellar protein FlaG
A7L45_RS14605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A7L45_RS14620	COG4786	Flagellar basal body rod
A7L45_RS14620	COG1256	bacterial-type flagellum assembly
A7L45_RS14635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7L45_RS14635	COG1776	CheC inhibitor of MCP methylation
A7L45_RS14640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7L45_RS14645	COG0835	chemotaxis
A7L45_RS14650	COG2201	protein-glutamate methylesterase activity
A7L45_RS14655	COG1776	CheC inhibitor of MCP methylation
A7L45_RS14660	COG0643	Histidine kinase
A7L45_RS14660	COG2198	Histidine kinase
A7L45_RS14665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A7L45_RS14670	COG2201	protein-glutamate methylesterase activity
A7L45_RS14680	COG0835	chemotaxis
A7L45_RS14715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7L45_RS14740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A7L45_RS14740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7L45_RS14745	COG0612	Peptidase, M16
A7L45_RS14755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7L45_RS14760	COG0187	DNA topoisomerase II activity
A7L45_RS14770	COG1132	(ABC) transporter
A7L45_RS14785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A7L45_RS14790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7L45_RS14795	COG5658	integral membrane protein
A7L45_RS14800	COG0640	Transcriptional regulator
A7L45_RS14815	COG0519	Catalyzes the synthesis of GMP from XMP
A7L45_RS14825	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7L45_RS14850	COG1418	mRNA catabolic process
A7L45_RS14860	COG0110	maltose O-acetyltransferase activity
A7L45_RS14875	COG0546	phosphoglycolate phosphatase activity
A7L45_RS14890	COG2813	Specifically methylates the guanine in position
A7L45_RS14920	COG1131	(ABC) transporter
A7L45_RS14945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7L45_RS14945	COG0723	plastoquinol--plastocyanin reductase activity
A7L45_RS14965	COG0456	acetyltransferase
A7L45_RS14980	COG0242	peptide deformylase activity
A7L45_RS14985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7L45_RS14995	COG0840	transmembrane signaling receptor activity
A7L45_RS15000	COG1773	rubredoxin
A7L45_RS15000	COG0426	domain, Protein
A7L45_RS15040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7L45_RS15045	COG1181	Belongs to the D-alanine--D-alanine ligase family
A7L45_RS15060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A7L45_RS15075	COG2226	methyltransferase
A7L45_RS15090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7L45_RS15110	COG0756	dUTP diphosphatase activity
A7L45_RS15125	COG0730	response to heat
A7L45_RS15130	COG0151	Belongs to the GarS family
A7L45_RS15140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A7L45_RS15145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A7L45_RS15150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7L45_RS15160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7L45_RS15175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7L45_RS15190	COG0183	Belongs to the thiolase family
A7L45_RS15200	COG1151	hydroxylamine reductase activity
A7L45_RS15215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7L45_RS15230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A7L45_RS15235	COG0358	DNA primase activity
A7L45_RS15255	COG0574	Belongs to the PEP-utilizing enzyme family
A7L45_RS15255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7L45_RS15265	COG1381	Involved in DNA repair and RecF pathway recombination
A7L45_RS15270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A7L45_RS15275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A7L45_RS15285	COG1480	7TM receptor with intracellular HD hydrolase
A7L45_RS15305	COG0537	adenosine 5'-monophosphoramidase activity
A7L45_RS15310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7L45_RS15320	COG0484	heat shock protein binding
A7L45_RS15325	COG0443	Heat shock 70 kDa protein
A7L45_RS15330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A7L45_RS15340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7L45_RS15345	COG0481	GTPase activity
A7L45_RS15365	COG0268	Binds directly to 16S ribosomal RNA
A7L45_RS15375	COG2333	competence protein COMEC
A7L45_RS15375	COG0658	competence protein
A7L45_RS15380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7L45_RS15405	COG1596	polysaccharide export
A7L45_RS15405	COG1555	photosystem II stabilization
A7L45_RS15410	COG1686	Belongs to the peptidase S11 family
A7L45_RS15415	COG0564	pseudouridine synthase activity
A7L45_RS15420	COG0251	oxidation-reduction process
A7L45_RS15430	COG1713	HD superfamily hydrolase involved in NAD metabolism
A7L45_RS15435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A7L45_RS15440	COG1534	Rna-binding protein
A7L45_RS15445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7L45_RS15460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A7L45_RS15465	COG1530	ribonuclease E activity
A7L45_RS15480	COG1994	Peptidase M50
A7L45_RS15490	COG1803	Methylglyoxal synthase
A7L45_RS15495	COG0772	Belongs to the SEDS family
A7L45_RS15500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A7L45_RS15505	COG2894	cell division
A7L45_RS15510	COG0850	regulation of cytokinetic process
A7L45_RS15520	COG1792	Involved in formation and maintenance of cell shape
A7L45_RS15525	COG1077	Cell shape determining protein MreB Mrl
A7L45_RS15565	COG0237	dephospho-CoA kinase activity
A7L45_RS15570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7L45_RS15570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7L45_RS15580	COG0840	transmembrane signaling receptor activity
A7L45_RS15585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7L45_RS15590	COG1522	sequence-specific DNA binding
A7L45_RS15595	COG0640	Transcriptional regulator
A7L45_RS15620	COG1959	2 iron, 2 sulfur cluster binding
A7L45_RS15625	COG1335	isochorismatase
A7L45_RS15635	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7L45_RS15660	COG2723	6-phospho-beta-galactosidase activity
A7L45_RS15665	COG2190	(PTS) system
A7L45_RS15665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS15665	COG1263	PTS System
A7L45_RS15670	COG1263	PTS System
A7L45_RS15670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS15670	COG2190	(PTS) system
A7L45_RS15675	COG3711	transcriptional antiterminator
A7L45_RS15685	COG1486	melibiose metabolic process
A7L45_RS15690	COG1737	Transcriptional regulator
A7L45_RS15705	COG0840	transmembrane signaling receptor activity
A7L45_RS15710	COG0640	Transcriptional regulator
A7L45_RS15715	COG2217	Heavy metal translocating P-type atpase
A7L45_RS15725	COG1737	Transcriptional regulator
A7L45_RS15735	COG0123	including yeast histone deacetylase and acetoin utilization protein
A7L45_RS15750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7L45_RS15760	COG0688	phosphatidylethanolamine metabolic process
A7L45_RS15775	COG2814	Major facilitator Superfamily
A7L45_RS15795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7L45_RS15820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A7L45_RS15825	COG2217	Heavy metal translocating P-type atpase
A7L45_RS15830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7L45_RS15830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7L45_RS15835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7L45_RS15855	COG1959	2 iron, 2 sulfur cluster binding
A7L45_RS15900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7L45_RS15900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A7L45_RS15905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7L45_RS15910	COG1418	mRNA catabolic process
A7L45_RS15915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7L45_RS15925	COG0613	PHP domain protein
A7L45_RS15930	COG1362	aminopeptidase activity
A7L45_RS15935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A7L45_RS15955	COG0426	domain, Protein
A7L45_RS15965	COG0157	Belongs to the NadC ModD family
A7L45_RS15970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7L45_RS15980	COG0242	peptide deformylase activity
A7L45_RS16010	COG2244	polysaccharide biosynthetic process
A7L45_RS16020	COG1473	amidohydrolase
A7L45_RS16025	COG0849	cell division
A7L45_RS16040	COG0210	DNA helicase
A7L45_RS16045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7L45_RS16070	COG1733	regulation of RNA biosynthetic process
A7L45_RS16085	COG1725	Transcriptional regulator
A7L45_RS16100	COG1686	Belongs to the peptidase S11 family
A7L45_RS16105	COG0697	spore germination
A7L45_RS16115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7L45_RS16125	COG4717	serine-type aminopeptidase activity
A7L45_RS16125	COG4717	serine-type aminopeptidase activity
A7L45_RS16150	COG0205	6-phosphofructokinase activity
A7L45_RS16160	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A7L45_RS16170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A7L45_RS16205	COG1331	Highly conserved protein containing a thioredoxin domain
A7L45_RS16225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A7L45_RS16240	COG3546	catalase activity
A7L45_RS16270	COG1408	metallophosphoesterase
A7L45_RS16280	COG0469	pyruvate kinase activity
A7L45_RS16290	COG2199	diguanylate cyclase activity
A7L45_RS16300	COG2357	RelA SpoT domain protein
A7L45_RS16305	COG0583	DNA-binding transcription factor activity
A7L45_RS16310	COG1132	(ABC) transporter
A7L45_RS16330	COG1131	(ABC) transporter
A7L45_RS16350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7L45_RS16355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7L45_RS16380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A7L45_RS16425	COG1459	type II secretion system
A7L45_RS16430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7L45_RS16440	COG0281	malic enzyme
A7L45_RS16445	COG3290	protein histidine kinase activity
A7L45_RS16450	COG4565	transcriptional regulatory protein
A7L45_RS16460	COG1131	(ABC) transporter
A7L45_RS16470	COG1131	(ABC) transporter
A7L45_RS16475	COG1725	Transcriptional regulator
A7L45_RS16480	COG5002	protein histidine kinase activity
A7L45_RS16485	COG0745	RESPONSE REGULATOR receiver
A7L45_RS16500	COG0577	efflux transmembrane transporter activity
A7L45_RS16500	COG1136	(ABC) transporter
A7L45_RS16545	COG3594	Acyltransferase
A7L45_RS16685	COG0629	single-stranded DNA binding
A7L45_RS16705	COG1484	DNA-dependent DNA replication
A7L45_RS16750	COG3645	SOS response
A7L45_RS16750	COG3646	Phage regulatory protein
A7L45_RS16765	COG1396	sequence-specific DNA binding
A7L45_RS16770	COG0582	viral genome integration into host DNA
A7L45_RS16785	COG3414	Phosphotransferase system galactitol-specific IIB component
A7L45_RS16790	COG1609	Transcriptional regulator
A7L45_RS16795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A7L45_RS16800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A7L45_RS16810	COG0436	Aminotransferase
A7L45_RS16825	COG2235	arginine
A7L45_RS16830	COG0833	amino acid
A7L45_RS16835	COG4187	Peptidase family M20/M25/M40
A7L45_RS16845	COG3804	dihydrodipicolinate reductase
A7L45_RS16850	COG3457	Alanine racemase
A7L45_RS16860	COG5012	cobalamin binding
A7L45_RS16870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7L45_RS16880	COG3829	transcription factor binding
A7L45_RS16890	COG1940	carbohydrate kinase activity
A7L45_RS16900	COG2972	Histidine kinase
A7L45_RS16905	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS16910	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS16915	COG1129	ABC transporter
A7L45_RS16920	COG1879	ABC-type sugar transport system periplasmic component
A7L45_RS16925	COG1879	ABC-type sugar transport system periplasmic component
A7L45_RS16930	COG3279	Response regulator of the LytR AlgR family
A7L45_RS16935	COG0778	Nitroreductase
A7L45_RS16940	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A7L45_RS16945	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A7L45_RS16950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A7L45_RS16955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7L45_RS16960	COG2116	formate transmembrane transporter activity
A7L45_RS16965	COG1151	hydroxylamine reductase activity
A7L45_RS16970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7L45_RS16975	COG0028	Belongs to the TPP enzyme family
A7L45_RS16980	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A7L45_RS16985	COG0440	acetolactate synthase activity
A7L45_RS16990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A7L45_RS16995	COG0066	3-isopropylmalate dehydratase activity
A7L45_RS17000	COG0473	3-isopropylmalate dehydrogenase activity
A7L45_RS17005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7L45_RS17010	COG0673	inositol 2-dehydrogenase activity
A7L45_RS17035	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS17035	COG1216	Glycosyl transferase, family 2
A7L45_RS17040	COG0457	Tetratricopeptide repeat
A7L45_RS17040	COG0463	Glycosyl transferase, family 2
A7L45_RS17045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7L45_RS17050	COG0110	maltose O-acetyltransferase activity
A7L45_RS17055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7L45_RS17065	COG0457	Tetratricopeptide repeat
A7L45_RS17065	COG0463	Glycosyl transferase, family 2
A7L45_RS17110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7L45_RS17115	COG1216	Glycosyl transferase, family 2
A7L45_RS17115	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS17120	COG0463	Glycosyl transferase, family 2
A7L45_RS17140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7L45_RS17150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A7L45_RS17195	COG0833	amino acid
A7L45_RS17205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7L45_RS17210	COG1191	sigma factor activity
A7L45_RS17215	COG0039	L-malate dehydrogenase activity
A7L45_RS17235	COG1966	Carbon starvation protein
A7L45_RS17240	COG3275	phosphorelay sensor kinase activity
A7L45_RS17250	COG0561	phosphatase activity
A7L45_RS17275	COG1131	(ABC) transporter
A7L45_RS17280	COG2197	response regulator
A7L45_RS17285	COG4585	Histidine kinase
A7L45_RS17290	COG1376	ErfK ybiS ycfS ynhG family protein
A7L45_RS17295	COG0840	transmembrane signaling receptor activity
A7L45_RS17300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A7L45_RS17330	COG2252	PERMEase
A7L45_RS17335	COG0402	S-adenosylhomocysteine deaminase activity
A7L45_RS17345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7L45_RS17350	COG0402	S-adenosylhomocysteine deaminase activity
A7L45_RS17355	COG0493	'glutamate synthase
A7L45_RS17355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A7L45_RS17360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7L45_RS17370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7L45_RS17405	COG1376	ErfK ybiS ycfS ynhG family protein
A7L45_RS17435	COG0531	amino acid
A7L45_RS17445	COG0024	Methionine aminopeptidase
A7L45_RS17450	COG1132	(ABC) transporter
A7L45_RS17455	COG1132	(ABC) transporter
A7L45_RS17465	COG0395	ABC-type sugar transport system, permease component
A7L45_RS17470	COG1175	transmembrane transport
A7L45_RS17475	COG0584	glycerophosphoryl diester phosphodiesterase
A7L45_RS17480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7L45_RS17485	COG0028	Belongs to the TPP enzyme family
A7L45_RS17495	COG0726	polysaccharide deacetylase
A7L45_RS17510	COG0598	Magnesium transport protein CorA
A7L45_RS17535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7L45_RS17540	COG1472	Belongs to the glycosyl hydrolase 3 family
A7L45_RS17545	COG0395	ABC-type sugar transport system, permease component
A7L45_RS17550	COG1175	transmembrane transport
A7L45_RS17560	COG2207	Transcriptional regulator
A7L45_RS17560	COG4753	response regulator
A7L45_RS17565	COG2972	Histidine kinase
A7L45_RS17570	COG2720	vancomycin resistance protein
A7L45_RS17600	COG5002	protein histidine kinase activity
A7L45_RS17605	COG2205	protein histidine kinase activity
A7L45_RS17610	COG0745	RESPONSE REGULATOR receiver
A7L45_RS17615	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A7L45_RS17620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A7L45_RS17625	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A7L45_RS17640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A7L45_RS17645	COG0006	proline dipeptidase activity
A7L45_RS17660	COG0488	(ABC) transporter
A7L45_RS17670	COG0514	ATP-dependent DNA helicase (RecQ)
A7L45_RS17675	COG0745	RESPONSE REGULATOR receiver
A7L45_RS17680	COG3279	Response regulator of the LytR AlgR family
A7L45_RS17685	COG3275	phosphorelay sensor kinase activity
A7L45_RS17690	COG1666	GTP binding
A7L45_RS17695	COG2002	toxin-antitoxin pair type II binding
A7L45_RS17705	COG1199	ATP-dependent helicase activity
A7L45_RS17710	COG0488	(ABC) transporter
A7L45_RS17715	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A7L45_RS17725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A7L45_RS17730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7L45_RS17735	COG0569	domain protein
A7L45_RS17740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7L45_RS17745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A7L45_RS17755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A7L45_RS17815	COG2226	methyltransferase
A7L45_RS17825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7L45_RS17830	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A7L45_RS17835	COG0436	Aminotransferase
A7L45_RS17840	COG2171	N-acyltransferase activity
A7L45_RS17850	COG0726	polysaccharide deacetylase
A7L45_RS17870	COG0285	dihydrofolate synthase activity
A7L45_RS17875	COG4608	Belongs to the ABC transporter superfamily
A7L45_RS17880	COG0444	Belongs to the ABC transporter superfamily
A7L45_RS17885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7L45_RS17890	COG0601	transmembrane transport
A7L45_RS17905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7L45_RS17910	COG2746	aminoglycoside 3-N-acetyltransferase activity
A7L45_RS17920	COG1136	(ABC) transporter
A7L45_RS17925	COG5002	protein histidine kinase activity
A7L45_RS17930	COG0745	RESPONSE REGULATOR receiver
A7L45_RS17945	COG3588	fructose-bisphosphate aldolase
A7L45_RS17955	COG1695	Transcriptional regulator
A7L45_RS17970	COG1116	anion transmembrane transporter activity
A7L45_RS17975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7L45_RS17985	COG2801	Transposase and inactivated derivatives
A7L45_RS18000	COG2137	regulation of response to DNA damage stimulus
A7L45_RS18005	COG0612	Peptidase, M16
A7L45_RS18015	COG0513	Belongs to the DEAD box helicase family
A7L45_RS18020	COG1285	pathogenesis
A7L45_RS18040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7L45_RS18045	COG0617	tRNA 3'-terminal CCA addition
A7L45_RS18050	COG3906	Belongs to the UPF0473 family
A7L45_RS18055	COG0617	tRNA 3'-terminal CCA addition
A7L45_RS18065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7L45_RS18070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7L45_RS18105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7L45_RS18110	COG3853	Toxic anion resistance protein (TelA)
A7L45_RS18135	COG1477	protein flavinylation
A7L45_RS18145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7L45_RS18165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A7L45_RS18170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7L45_RS18170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7L45_RS18185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7L45_RS18190	COG0765	amino acid transport
A7L45_RS18195	COG1126	abc transporter atp-binding protein
A7L45_RS18200	COG3507	Belongs to the glycosyl hydrolase 43 family
A7L45_RS18215	COG0671	phosphoesterase, PA-phosphatase related
A7L45_RS18220	COG0301	tRNA thio-modification
A7L45_RS18225	COG1104	cysteine desulfurase activity
A7L45_RS18250	COG0534	Mate efflux family protein
A7L45_RS18270	COG2188	Transcriptional regulator
A7L45_RS18275	COG1131	(ABC) transporter
A7L45_RS18305	COG2217	Heavy metal translocating P-type atpase
A7L45_RS18315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A7L45_RS18315	COG0646	methionine synthase
A7L45_RS18320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7L45_RS18330	COG0531	amino acid
A7L45_RS18335	COG3507	Belongs to the glycosyl hydrolase 43 family
A7L45_RS18355	COG3534	alpha-L-arabinofuranosidase
A7L45_RS18360	COG1653	transport
A7L45_RS18365	COG1175	transmembrane transport
A7L45_RS18370	COG0395	ABC-type sugar transport system, permease component
A7L45_RS18375	COG3940	Belongs to the glycosyl hydrolase 43 family
A7L45_RS18390	COG2207	Transcriptional regulator
A7L45_RS18395	COG1164	Oligoendopeptidase f
A7L45_RS18415	COG0330	HflC and HflK could
A7L45_RS18425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7L45_RS18425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7L45_RS18490	COG1131	(ABC) transporter
A7L45_RS18510	COG0477	Major facilitator Superfamily
A7L45_RS18515	COG1309	transcriptional regulator
A7L45_RS18520	COG0772	Belongs to the SEDS family
A7L45_RS18525	COG0840	transmembrane signaling receptor activity
A7L45_RS18535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A7L45_RS18540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A7L45_RS18545	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A7L45_RS18550	COG2155	Conserved Protein
A7L45_RS18570	COG0658	competence protein
A7L45_RS18570	COG2333	competence protein COMEC
A7L45_RS18580	COG0697	spore germination
A7L45_RS18585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7L45_RS18590	COG3442	glutamine amidotransferase
A7L45_RS18610	COG5002	protein histidine kinase activity
A7L45_RS18620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7L45_RS18625	COG0457	Tetratricopeptide repeat
A7L45_RS18625	COG0705	Rhomboid family
A7L45_RS18645	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7L45_RS18680	COG0840	transmembrane signaling receptor activity
A7L45_RS18710	COG2197	response regulator
A7L45_RS18715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7L45_RS18740	COG0745	RESPONSE REGULATOR receiver
A7L45_RS18760	COG0840	transmembrane signaling receptor activity
A7L45_RS18795	COG1609	Transcriptional regulator
A7L45_RS18800	COG1879	ABC-type sugar transport system periplasmic component
A7L45_RS18805	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS18825	COG1316	TRANSCRIPTIONal
A7L45_RS18845	COG0463	Glycosyl transferase, family 2
A7L45_RS18935	COG5001	Diguanylate cyclase
A7L45_RS19005	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS19010	COG1216	Glycosyl transferase, family 2
A7L45_RS19010	COG1442	glycosyl transferase family 8
A7L45_RS19015	COG0438	transferase activity, transferring glycosyl groups
A7L45_RS19030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7L45_RS19040	COG0489	protein tyrosine kinase activity
A7L45_RS19050	COG3944	biosynthesis protein
A7L45_RS19090	COG0737	Belongs to the 5'-nucleotidase family
A7L45_RS19110	COG1307	EDD domain protein, DegV family
A7L45_RS19115	COG4193	domain, Protein
A7L45_RS19120	COG2099	Precorrin-6x reductase
A7L45_RS19145	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
A7L45_RS19165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7L45_RS19190	COG0588	phosphoglycerate mutase activity
A7L45_RS19205	COG1121	(ABC) transporter
A7L45_RS19210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7L45_RS19230	COG1079	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS19235	COG4603	Belongs to the binding-protein-dependent transport system permease family
A7L45_RS19240	COG3845	ABC transporter
A7L45_RS19250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7L45_RS19255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7L45_RS19260	COG0058	SHG alpha-glucan phosphorylase activity
A7L45_RS19265	COG0297	glycogen (starch) synthase activity
A7L45_RS19270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7L45_RS19275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7L45_RS19300	COG0242	peptide deformylase activity
A7L45_RS19325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A7L45_RS19330	COG0113	porphobilinogen synthase activity
A7L45_RS19370	COG1994	Peptidase M50
A7L45_RS19385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A7L45_RS19390	COG0735	belongs to the Fur family
A7L45_RS19425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A7L45_RS19430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7L45_RS19435	COG0470	DNA polymerase III
A7L45_RS19435	COG1067	ATP-dependent peptidase activity
A7L45_RS19445	COG0740	serine-type endopeptidase activity
A7L45_RS19475	COG1357	PFAM Pentapeptide repeats (8 copies)
A7L45_RS19490	COG0167	dihydroorotate dehydrogenase activity
A7L45_RS19495	COG0543	2 iron, 2 sulfur cluster binding
A7L45_RS19500	COG0284	orotidine-5'-phosphate decarboxylase activity
A7L45_RS19530	COG0582	viral genome integration into host DNA
A7L45_RS19550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7L45_RS19590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7L45_RS19625	COG0622	Phosphoesterase
A7L45_RS19630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A7L45_RS19640	COG4166	transmembrane transport
A7L45_RS19645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7L45_RS19650	COG0798	PFAM Bile acid sodium symporter
A7L45_RS19690	COG2205	protein histidine kinase activity
A7L45_RS19695	COG3689	TIGRFAM TIGR03943 family protein
A7L45_RS19700	COG0701	Predicted permease
A7L45_RS19705	COG0523	cobalamin synthesis protein
A7L45_RS19710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7L45_RS19715	COG1121	(ABC) transporter
A7L45_RS19720	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7L45_RS19730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7L45_RS19735	COG3829	transcription factor binding
A7L45_RS19745	COG0310	cobalt ion transport
A7L45_RS19750	COG1122	ATPase activity
A7L45_RS19770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A7L45_RS19775	COG0210	DNA helicase
A7L45_RS19780	COG4496	protein, YerC YecD
A7L45_RS19790	COG0148	phosphopyruvate hydratase activity
A7L45_RS19805	COG0126	phosphoglycerate kinase activity
A7L45_RS19810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7L45_RS19820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A7L45_RS19830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A7L45_RS19835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7L45_RS19840	COG2720	vancomycin resistance protein
A7L45_RS19845	COG1363	Peptidase, m42
A7L45_RS19865	COG2239	Acts as a magnesium transporter
A7L45_RS19870	COG1032	radical SAM domain protein
A7L45_RS19880	COG1597	lipid kinase activity
A7L45_RS19885	COG0517	IMP dehydrogenase activity
A7L45_RS19890	COG1183	phosphatidylcholine synthase activity
A7L45_RS19900	COG1760	l-serine dehydratase
A7L45_RS19915	COG2323	membrane
A7L45_RS19925	COG0191	fructose-bisphosphate aldolase activity
A7L45_RS19945	COG0484	heat shock protein binding
A7L45_RS19960	COG2357	RelA SpoT domain protein
A7L45_RS20000	COG0697	spore germination
A7L45_RS20015	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A7L45_RS20040	COG2033	superoxide reductase activity
A7L45_RS20050	COG3459	Glycosyltransferase 36 associated
A7L45_RS20055	COG1362	aminopeptidase activity
A7L45_RS20075	COG0367	asparagine synthase
A7L45_RS20090	COG5002	protein histidine kinase activity
A7L45_RS20100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7L45_RS20100	COG1263	PTS System
A7L45_RS20100	COG2190	(PTS) system
A7L45_RS20105	COG3711	transcriptional antiterminator
A7L45_RS20150	COG2323	membrane
A7L45_RS20160	COG3973	AAA domain
A7L45_RS20165	COG4948	Mandelate Racemase Muconate Lactonizing
A7L45_RS20170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7L45_RS20205	COG0469	pyruvate kinase activity
A7L45_RS20210	COG0205	6-phosphofructokinase activity
A7L45_RS20220	COG4109	DRTGG domain
A7L45_RS20225	COG1481	regulation of sporulation
A7L45_RS20230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7L45_RS20240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A7L45_RS20245	COG0322	excinuclease ABC activity
A7L45_RS20250	COG0768	penicillin binding
A7L45_RS20275	COG0717	Belongs to the dCTP deaminase family
A7L45_RS20290	COG0488	(ABC) transporter
A7L45_RS20300	COG0793	Belongs to the peptidase S41A family
A7L45_RS20300	COG3409	Peptidoglycan-binding domain 1 protein
A7L45_RS20305	COG2177	Part of the ABC transporter FtsEX involved in
A7L45_RS20310	COG2884	Cell division ATP-binding protein ftsE
A7L45_RS20325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7L45_RS20335	COG0736	holo-[acyl-carrier-protein] synthase activity
A7L45_RS20350	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7L45_RS20355	COG0561	phosphatase activity
A7L45_RS20365	COG1733	regulation of RNA biosynthetic process
A7L45_RS20375	COG1125	glycine betaine transport
A7L45_RS20375	COG0517	IMP dehydrogenase activity
A7L45_RS20390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7L45_RS20400	COG0778	Nitroreductase
A7L45_RS20410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7L45_RS20415	COG2239	Acts as a magnesium transporter
A7L45_RS20420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7L45_RS20450	COG5002	protein histidine kinase activity
A7L45_RS20465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7L45_RS20465	COG1918	ferrous iron import across plasma membrane
A7L45_RS20485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A7L45_RS20490	COG1253	flavin adenine dinucleotide binding
A7L45_RS20495	COG1253	flavin adenine dinucleotide binding
A7L45_RS20510	COG1136	(ABC) transporter
A7L45_RS20525	COG1091	dTDP-4-dehydrorhamnose reductase activity
A7L45_RS20560	COG0489	protein tyrosine kinase activity
A7L45_RS20570	COG1442	glycosyl transferase family 8
A7L45_RS20570	COG1216	Glycosyl transferase, family 2
A7L45_RS20575	COG1216	Glycosyl transferase, family 2
A7L45_RS20580	COG1216	Glycosyl transferase, family 2
A7L45_RS20580	COG0463	Glycosyl transferase, family 2
A7L45_RS20590	COG5039	Polysaccharide pyruvyl transferase
A7L45_RS20595	COG1442	glycosyl transferase family 8
A7L45_RS20595	COG1216	Glycosyl transferase, family 2
A7L45_RS20615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7L45_RS20620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7L45_RS20625	COG1295	ribonuclease BN
A7L45_RS20635	COG0138	bifunctional purine biosynthesis protein purh
A7L45_RS20640	COG3326	Membrane
A7L45_RS20650	COG0419	ATPase involved in DNA repair
A7L45_RS20655	COG0420	3'-5' exonuclease activity
A7L45_RS20660	COG1074	ATP-dependent DNA helicase activity
A7L45_RS20665	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A7L45_RS20675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7L45_RS20705	COG1349	DNA-binding transcription factor activity
A7L45_RS20710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7L45_RS20720	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A7L45_RS20725	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7L45_RS20730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7L45_RS20755	COG1725	Transcriptional regulator
A7L45_RS20780	COG1592	Rubrerythrin
A7L45_RS20785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A7L45_RS20790	COG1464	Belongs to the NlpA lipoprotein family
A7L45_RS20795	COG2011	ABC-type metal ion transport system permease component
A7L45_RS20805	COG1742	UPF0060 membrane protein
A7L45_RS20810	COG1773	rubredoxin
A7L45_RS20815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7L45_RS20820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7L45_RS20830	COG0310	cobalt ion transport
A7L45_RS20835	COG1122	ATPase activity
A7L45_RS20845	COG0746	molybdenum cofactor guanylyltransferase activity
A7L45_RS20850	COG1763	Mo-molybdopterin cofactor biosynthetic process
A7L45_RS20865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7L45_RS20875	COG0243	molybdopterin cofactor binding
A7L45_RS20880	COG0315	cyclic pyranopterin monophosphate synthase activity
A7L45_RS20885	COG1151	hydroxylamine reductase activity
A7L45_RS20935	COG1595	DNA-templated transcription, initiation
A7L45_RS20945	COG1131	(ABC) transporter
A7L45_RS20960	COG3546	catalase activity
A7L45_RS20990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7L45_RS20995	COG3426	butyrate kinase activity
A7L45_RS21000	COG0280	phosphate acetyltransferase
A7L45_RS21005	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A7L45_RS21015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7L45_RS21030	COG0492	ferredoxin-NADP+ reductase activity
A7L45_RS21035	COG3118	belongs to the thioredoxin family
A7L45_RS21065	COG0101	tRNA pseudouridine synthase activity
A7L45_RS21070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7L45_RS21080	COG1122	ATPase activity
A7L45_RS21110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A7L45_RS21130	COG0201	protein transport
A7L45_RS21140	COG1841	ribosomal large subunit assembly
A7L45_RS21145	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A7L45_RS21150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A7L45_RS21155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A7L45_RS21170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7L45_RS21185	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A7L45_RS21190	COG0255	Belongs to the universal ribosomal protein uL29 family
A7L45_RS21205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A7L45_RS21215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7L45_RS21235	COG0051	transcription antitermination factor activity, RNA binding
A7L45_RS21240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7L45_RS21245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A7L45_RS21250	COG0049	tRNA binding
A7L45_RS21260	COG1358	cellular component organization or biogenesis
A7L45_RS21270	COG0085	RNA polymerase activity
A7L45_RS21300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7L45_RS21305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7L45_RS21310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7L45_RS21330	COG3688	RNA-binding protein containing a PIN domain
A7L45_RS21335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7L45_RS21350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A7L45_RS21355	COG4956	integral membrane protein (PIN domain superfamily)
A7L45_RS21370	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A7L45_RS21375	COG0542	response to heat
A7L45_RS21385	COG0006	proline dipeptidase activity
A7L45_RS21460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A7L45_RS21465	COG0423	glycine-tRNA ligase activity
A7L45_RS21475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A7L45_RS21480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A7L45_RS21485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7L45_RS21495	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A7L45_RS21500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7L45_RS21510	COG0037	tRNA processing
A7L45_RS21515	COG2208	phosphoserine phosphatase activity
A7L45_RS21570	COG1098	S1 RNA binding domain
A7L45_RS21590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A7L45_RS21600	COG3956	TIGRFAM MazG family protein
A7L45_RS21605	COG2244	polysaccharide biosynthetic process
A7L45_RS21610	COG2002	toxin-antitoxin pair type II binding
A7L45_RS21615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7L45_RS21620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A7L45_RS21625	COG0193	aminoacyl-tRNA hydrolase activity
A7L45_RS21630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7L45_RS21635	COG5002	protein histidine kinase activity
A7L45_RS21635	COG3850	Histidine kinase
A7L45_RS21640	COG0745	RESPONSE REGULATOR receiver
A7L45_RS21650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A7L45_RS21655	COG2088	sporulation resulting in formation of a cellular spore
A7L45_RS21660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7L45_RS21665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A7L45_RS21685	COG0671	phosphoesterase, PA-phosphatase related
A7L45_RS21690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7L45_RS21705	COG0488	(ABC) transporter
A7L45_RS21710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A7L45_RS21715	COG2045	Belongs to the ComB family
A7L45_RS21720	COG2508	Transcriptional regulator
A7L45_RS21725	COG3842	ATPase activity
A7L45_RS21730	COG1242	4 iron, 4 sulfur cluster binding
A7L45_RS21740	COG3949	Membrane
A7L45_RS21750	COG0840	transmembrane signaling receptor activity
A7L45_RS21750	COG3290	protein histidine kinase activity
A7L45_RS21765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7L45_RS21775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A7L45_RS21795	COG1132	(ABC) transporter
A7L45_RS21800	COG1132	(ABC) transporter
A7L45_RS21810	COG0653	protein targeting
A7L45_RS21815	COG5401	PFAM Sporulation and spore germination
A7L45_RS21820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7L45_RS21855	COG1404	Belongs to the peptidase S8 family
A7L45_RS21865	COG1058	Belongs to the CinA family
A7L45_RS21865	COG1546	Belongs to the CinA family
A7L45_RS21870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7L45_RS21880	COG3706	GGDEF domain
A7L45_RS21890	COG0024	Methionine aminopeptidase
A7L45_RS21905	COG0745	RESPONSE REGULATOR receiver
A7L45_RS21910	COG5002	protein histidine kinase activity
A7L45_RS21920	COG1131	(ABC) transporter
A7L45_RS21930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7L45_RS21945	COG0825	malonyl-CoA metabolic process
A7L45_RS21950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A7L45_RS21955	COG0439	Biotin carboxylase
A7L45_RS21960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7L45_RS21965	COG0511	ligase activity, forming carbon-carbon bonds
A7L45_RS21970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7L45_RS21975	COG1028	Short-chain dehydrogenase reductase Sdr
A7L45_RS21980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7L45_RS21985	COG2070	2-Nitropropane dioxygenase
A7L45_RS21990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7L45_RS21995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7L45_RS22015	COG3148	PFAM DTW domain containing protein
A7L45_RS22040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7L45_RS22100	COG2081	HI0933 family
A7L45_RS22130	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A7L45_RS22130	COG0644	oxidoreductase
A7L45_RS22145	COG0791	NLP P60 protein
A7L45_RS22155	COG2314	TM2 domain
A7L45_RS22170	COG0305	Participates in initiation and elongation during chromosome replication
A7L45_RS22175	COG1067	ATP-dependent peptidase activity
A7L45_RS22175	COG0470	DNA polymerase III
A7L45_RS22185	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7L45_RS22200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A7L45_RS22205	COG0629	single-stranded DNA binding
A7L45_RS22210	COG0360	Binds together with S18 to 16S ribosomal RNA
A7L45_RS22225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7L45_RS22230	COG0628	permease
A7L45_RS22250	COG1475	DNA binding
A7L45_RS22255	COG1192	Involved in chromosome partitioning
A7L45_RS22260	COG1475	DNA binding
A7L45_RS22265	COG0357	Ribosomal RNA small subunit methyltransferase G
A7L45_RS22275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A7L45_RS22280	COG1847	R3H domain protein
A7L45_RS22355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7L45_RS22360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner