locus-tag	class	description
CLSAP_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLSAP_RS00010	COG0592	DNA-directed DNA polymerase activity
CLSAP_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLSAP_RS00030	COG0187	DNA topoisomerase II activity
CLSAP_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLSAP_RS00075	COG1827	regulation of RNA biosynthetic process
CLSAP_RS00110	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CLSAP_RS00115	COG1074	ATP-dependent DNA helicase activity
CLSAP_RS00120	COG1376	ErfK ybiS ycfS ynhG family protein
CLSAP_RS00130	COG5002	protein histidine kinase activity
CLSAP_RS00160	COG0688	phosphatidylethanolamine metabolic process
CLSAP_RS00170	COG0488	(ABC) transporter
CLSAP_RS00190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLSAP_RS00195	COG1803	Methylglyoxal synthase
CLSAP_RS00205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLSAP_RS00225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLSAP_RS00250	COG3949	Membrane
CLSAP_RS00255	COG1242	4 iron, 4 sulfur cluster binding
CLSAP_RS00260	COG2045	Belongs to the ComB family
CLSAP_RS00290	COG0534	Mate efflux family protein
CLSAP_RS00305	COG2715	membrane protein required for spore maturation
CLSAP_RS00310	COG0700	Nucleoside recognition
CLSAP_RS00315	COG0006	proline dipeptidase activity
CLSAP_RS00320	COG0006	proline dipeptidase activity
CLSAP_RS00330	COG0084	hydrolase, TatD family'
CLSAP_RS00335	COG3583	domain protein
CLSAP_RS00335	COG3584	3D domain protein
CLSAP_RS00340	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLSAP_RS00375	COG1141	Ferredoxin
CLSAP_RS00390	COG1328	CTP reductase activity
CLSAP_RS00395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLSAP_RS00400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLSAP_RS00405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLSAP_RS00420	COG2094	Belongs to the DNA glycosylase MPG family
CLSAP_RS00430	COG0463	Glycosyl transferase, family 2
CLSAP_RS00440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLSAP_RS00455	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS00480	COG5002	protein histidine kinase activity
CLSAP_RS00485	COG0017	Asparaginyl-tRNA synthetase
CLSAP_RS00495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLSAP_RS00500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLSAP_RS00505	COG2088	sporulation resulting in formation of a cellular spore
CLSAP_RS00510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLSAP_RS00520	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS00525	COG5002	protein histidine kinase activity
CLSAP_RS00530	COG0193	aminoacyl-tRNA hydrolase activity
CLSAP_RS00535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLSAP_RS00540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLSAP_RS00545	COG2002	toxin-antitoxin pair type II binding
CLSAP_RS00550	COG2244	polysaccharide biosynthetic process
CLSAP_RS00555	COG3956	TIGRFAM MazG family protein
CLSAP_RS00565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLSAP_RS00585	COG1098	S1 RNA binding domain
CLSAP_RS00605	COG2208	phosphoserine phosphatase activity
CLSAP_RS00610	COG0037	tRNA processing
CLSAP_RS00615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CLSAP_RS00620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLSAP_RS00625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CLSAP_RS00630	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CLSAP_RS00635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLSAP_RS00640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLSAP_RS00645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLSAP_RS00670	COG0423	glycine-tRNA ligase activity
CLSAP_RS00675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLSAP_RS00730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLSAP_RS00735	COG3870	Protein conserved in bacteria
CLSAP_RS00745	COG1774	PSP1 C-terminal conserved region
CLSAP_RS00760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CLSAP_RS00770	COG3880	PFAM UvrB UvrC protein
CLSAP_RS00780	COG0542	response to heat
CLSAP_RS00785	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLSAP_RS00790	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CLSAP_RS00795	COG4956	integral membrane protein (PIN domain superfamily)
CLSAP_RS00800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLSAP_RS00810	COG0215	cysteine-tRNA ligase activity
CLSAP_RS00820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLSAP_RS00840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLSAP_RS00845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLSAP_RS00860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLSAP_RS00865	COG0081	regulation of translation
CLSAP_RS00875	COG0222	ribosome binding
CLSAP_RS00880	COG0085	RNA polymerase activity
CLSAP_RS00885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLSAP_RS00895	COG0049	tRNA binding
CLSAP_RS00900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLSAP_RS00905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLSAP_RS00910	COG0051	transcription antitermination factor activity, RNA binding
CLSAP_RS00915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLSAP_RS00920	COG0088	Forms part of the polypeptide exit tunnel
CLSAP_RS00925	COG0089	rRNA binding
CLSAP_RS00930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLSAP_RS00935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLSAP_RS00940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLSAP_RS00945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLSAP_RS00950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLSAP_RS00955	COG0255	Belongs to the universal ribosomal protein uL29 family
CLSAP_RS00960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLSAP_RS00965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLSAP_RS00970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLSAP_RS00975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLSAP_RS00985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLSAP_RS00990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLSAP_RS00995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLSAP_RS01005	COG1841	ribosomal large subunit assembly
CLSAP_RS01010	COG0200	Binds to the 23S rRNA
CLSAP_RS01015	COG0201	protein transport
CLSAP_RS01020	COG0563	adenylate kinase activity
CLSAP_RS01035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLSAP_RS01040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLSAP_RS01045	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLSAP_RS01050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLSAP_RS01060	COG0202	RNA polymerase activity
CLSAP_RS01065	COG0203	ribosomal protein L17
CLSAP_RS01070	COG1122	ATPase activity
CLSAP_RS01075	COG1122	ATPase activity
CLSAP_RS01080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLSAP_RS01085	COG0101	tRNA pseudouridine synthase activity
CLSAP_RS01090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLSAP_RS01095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLSAP_RS01130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLSAP_RS01135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLSAP_RS01140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLSAP_RS01155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLSAP_RS01165	COG4842	Belongs to the WXG100 family
CLSAP_RS01230	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CLSAP_RS01235	COG0280	phosphate acetyltransferase
CLSAP_RS01240	COG3426	butyrate kinase activity
CLSAP_RS01255	COG1418	mRNA catabolic process
CLSAP_RS01260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLSAP_RS01265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLSAP_RS01265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLSAP_RS01275	COG4496	protein, YerC YecD
CLSAP_RS01280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLSAP_RS01300	COG4209	transmembrane transport
CLSAP_RS01305	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS01320	COG1501	Belongs to the glycosyl hydrolase 31 family
CLSAP_RS01325	COG1472	Belongs to the glycosyl hydrolase 3 family
CLSAP_RS01330	COG2972	Histidine kinase
CLSAP_RS01335	COG4753	response regulator
CLSAP_RS01335	COG2207	Transcriptional regulator
CLSAP_RS01345	COG0440	acetolactate synthase activity
CLSAP_RS01350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLSAP_RS01355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLSAP_RS01360	COG0066	3-isopropylmalate dehydratase activity
CLSAP_RS01365	COG0473	3-isopropylmalate dehydrogenase activity
CLSAP_RS01375	COG0028	Belongs to the TPP enzyme family
CLSAP_RS01380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLSAP_RS01390	COG1653	transport
CLSAP_RS01410	COG1609	Transcriptional regulator
CLSAP_RS01415	COG5278	phosphoserine phosphatase activity
CLSAP_RS01415	COG0840	transmembrane signaling receptor activity
CLSAP_RS01430	COG1136	(ABC) transporter
CLSAP_RS01435	COG0577	efflux transmembrane transporter activity
CLSAP_RS01435	COG1136	(ABC) transporter
CLSAP_RS01445	COG0626	cystathionine gamma-synthase activity
CLSAP_RS01450	COG0626	cystathionine gamma-synthase activity
CLSAP_RS01455	COG1846	Transcriptional regulator
CLSAP_RS01465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLSAP_RS01470	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLSAP_RS01475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLSAP_RS01480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLSAP_RS01490	COG1960	acyl-CoA dehydrogenase activity
CLSAP_RS01495	COG2086	electron transfer activity
CLSAP_RS01500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CLSAP_RS01515	COG1131	(ABC) transporter
CLSAP_RS01525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLSAP_RS01535	COG0318	PFAM AMP-dependent synthetase and ligase
CLSAP_RS01560	COG0512	Glutamine amidotransferase of anthranilate synthase
CLSAP_RS01560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLSAP_RS01565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLSAP_RS01570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLSAP_RS01580	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLSAP_RS01590	COG0058	SHG alpha-glucan phosphorylase activity
CLSAP_RS01595	COG2207	Transcriptional regulator
CLSAP_RS01595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLSAP_RS01610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLSAP_RS01640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLSAP_RS01645	COG1191	sigma factor activity
CLSAP_RS01650	COG0726	polysaccharide deacetylase
CLSAP_RS01660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLSAP_RS01670	COG3655	Transcriptional regulator
CLSAP_RS01685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLSAP_RS01695	COG2186	Transcriptional regulator
CLSAP_RS01700	COG1620	l-lactate permease
CLSAP_RS01705	COG2086	electron transfer activity
CLSAP_RS01710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CLSAP_RS01715	COG0277	FAD linked oxidase domain protein
CLSAP_RS01720	COG1595	DNA-templated transcription, initiation
CLSAP_RS01730	COG0747	negative chemotaxis
CLSAP_RS01735	COG0601	transmembrane transport
CLSAP_RS01740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLSAP_RS01745	COG0444	Belongs to the ABC transporter superfamily
CLSAP_RS01750	COG4608	Belongs to the ABC transporter superfamily
CLSAP_RS01755	COG5002	protein histidine kinase activity
CLSAP_RS01765	COG0438	transferase activity, transferring glycosyl groups
CLSAP_RS01770	COG1215	transferase activity, transferring glycosyl groups
CLSAP_RS01775	COG2204	response regulator
CLSAP_RS01785	COG0784	Response regulator, receiver
CLSAP_RS01785	COG2205	protein histidine kinase activity
CLSAP_RS01795	COG0662	Cupin 2, conserved barrel domain protein
CLSAP_RS01795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CLSAP_RS01840	COG3328	transposase activity
CLSAP_RS01845	COG3328	transposase activity
CLSAP_RS01855	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS01870	COG0210	DNA helicase
CLSAP_RS01895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLSAP_RS02120	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS02130	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS02135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS02140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLSAP_RS02155	COG2188	Transcriptional regulator
CLSAP_RS02170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CLSAP_RS02170	COG0662	Cupin 2, conserved barrel domain protein
CLSAP_RS02180	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CLSAP_RS02185	COG1024	Enoyl-CoA hydratase
CLSAP_RS02190	COG1960	acyl-CoA dehydrogenase activity
CLSAP_RS02195	COG2086	electron transfer activity
CLSAP_RS02205	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLSAP_RS02230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLSAP_RS02235	COG0459	protein refolding
CLSAP_RS02245	COG0516	GMP reductase activity
CLSAP_RS02245	COG0517	IMP dehydrogenase activity
CLSAP_RS02265	COG1131	(ABC) transporter
CLSAP_RS02275	COG0166	Belongs to the GPI family
CLSAP_RS02280	COG1671	Belongs to the UPF0178 family
CLSAP_RS02290	COG0741	lytic transglycosylase activity
CLSAP_RS02290	COG1196	nuclear chromosome segregation
CLSAP_RS02290	COG0739	heme binding
CLSAP_RS02295	COG1187	pseudouridine synthase activity
CLSAP_RS02300	COG0778	Nitroreductase
CLSAP_RS02305	COG1733	regulation of RNA biosynthetic process
CLSAP_RS02315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLSAP_RS02320	COG0840	transmembrane signaling receptor activity
CLSAP_RS02330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLSAP_RS02355	COG0622	Phosphoesterase
CLSAP_RS02425	COG3177	Filamentation induced by cAMP protein fic
CLSAP_RS02465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLSAP_RS02495	COG3590	peptidase
CLSAP_RS02525	COG0312	modulator of DNA gyrase
CLSAP_RS02530	COG0312	modulator of DNA gyrase
CLSAP_RS02540	COG2197	response regulator
CLSAP_RS02545	COG2207	Transcriptional regulator
CLSAP_RS02545	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS02550	COG0697	spore germination
CLSAP_RS02555	COG1131	(ABC) transporter
CLSAP_RS02570	COG1368	sulfuric ester hydrolase activity
CLSAP_RS02580	COG0492	ferredoxin-NADP+ reductase activity
CLSAP_RS02595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLSAP_RS02605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLSAP_RS02610	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS02640	COG3328	transposase activity
CLSAP_RS02645	COG0488	(ABC) transporter
CLSAP_RS02660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLSAP_RS02680	COG2382	esterase
CLSAP_RS02680	COG3507	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS02680	COG3693	PFAM glycoside hydrolase, family 10
CLSAP_RS02685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CLSAP_RS02685	COG3976	FMN-binding domain protein
CLSAP_RS02690	COG1357	PFAM Pentapeptide repeats (8 copies)
CLSAP_RS02700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLSAP_RS02780	COG0124	histidyl-tRNA synthetase
CLSAP_RS02845	COG4221	oxidoreductase activity
CLSAP_RS02865	COG0789	Transcriptional regulator
CLSAP_RS02900	COG3328	transposase activity
CLSAP_RS02915	COG4466	Protein conserved in bacteria
CLSAP_RS02920	COG0393	Putative heavy-metal-binding
CLSAP_RS02930	COG1388	LysM domain
CLSAP_RS02930	COG3858	chitin binding
CLSAP_RS02945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLSAP_RS02955	COG0482	sulfurtransferase activity
CLSAP_RS02970	COG0504	CTP synthase activity
CLSAP_RS02975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLSAP_RS02980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLSAP_RS02985	COG0254	rRNA binding
CLSAP_RS02990	COG1435	thymidine kinase activity
CLSAP_RS02995	COG2890	protein-(glutamine-N5) methyltransferase activity
CLSAP_RS03000	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLSAP_RS03010	COG0009	L-threonylcarbamoyladenylate synthase
CLSAP_RS03015	COG0698	ribose 5-phosphate isomerase
CLSAP_RS03020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLSAP_RS03030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLSAP_RS03035	COG0183	Belongs to the thiolase family
CLSAP_RS03045	COG0356	it plays a direct role in the translocation of protons across the membrane
CLSAP_RS03050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLSAP_RS03055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLSAP_RS03060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLSAP_RS03065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLSAP_RS03070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLSAP_RS03075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLSAP_RS03080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLSAP_RS03095	COG2385	sporulation resulting in formation of a cellular spore
CLSAP_RS03105	COG1609	Transcriptional regulator
CLSAP_RS03110	COG1077	Cell shape determining protein MreB Mrl
CLSAP_RS03150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLSAP_RS03160	COG1040	competence protein
CLSAP_RS03275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLSAP_RS03280	COG0653	protein targeting
CLSAP_RS03285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLSAP_RS03305	COG5002	protein histidine kinase activity
CLSAP_RS03315	COG2183	response to ionizing radiation
CLSAP_RS03335	COG2364	Membrane
CLSAP_RS03345	COG1940	carbohydrate kinase activity
CLSAP_RS03355	COG0840	transmembrane signaling receptor activity
CLSAP_RS03360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLSAP_RS03365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CLSAP_RS03370	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS03410	COG0791	NLP P60 protein
CLSAP_RS03425	COG3646	Phage regulatory protein
CLSAP_RS03425	COG3645	SOS response
CLSAP_RS03500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CLSAP_RS03510	COG1349	DNA-binding transcription factor activity
CLSAP_RS03515	COG0561	phosphatase activity
CLSAP_RS03520	COG1414	Transcriptional regulator
CLSAP_RS03525	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS03570	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS03585	COG4656	Part of a membrane complex involved in electron transport
CLSAP_RS03590	COG4658	electron transport chain
CLSAP_RS03595	COG4659	FMN binding
CLSAP_RS03600	COG4660	Part of a membrane complex involved in electron transport
CLSAP_RS03605	COG4657	Part of a membrane complex involved in electron transport
CLSAP_RS03610	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLSAP_RS03610	COG2878	Part of a membrane complex involved in electron transport
CLSAP_RS03620	COG1058	Belongs to the CinA family
CLSAP_RS03620	COG1546	Belongs to the CinA family
CLSAP_RS03650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLSAP_RS03655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CLSAP_RS03655	COG3608	succinylglutamate desuccinylase aspartoacylase
CLSAP_RS03705	COG1136	(ABC) transporter
CLSAP_RS03715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLSAP_RS03720	COG1309	transcriptional regulator
CLSAP_RS03735	COG2703	oxygen carrier activity
CLSAP_RS03750	COG2190	(PTS) system
CLSAP_RS03750	COG1263	PTS System
CLSAP_RS03750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS03755	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLSAP_RS03760	COG1773	rubredoxin
CLSAP_RS03765	COG0456	acetyltransferase
CLSAP_RS03770	COG1214	PFAM Peptidase M22, glycoprotease
CLSAP_RS03775	COG0802	atpase or kinase
CLSAP_RS03800	COG4303	Ethanolamine ammonia lyase large subunit
CLSAP_RS03805	COG4302	ethanolamine ammonia-lyase activity
CLSAP_RS03810	COG0251	oxidation-reduction process
CLSAP_RS03815	COG2070	2-Nitropropane dioxygenase
CLSAP_RS03865	COG0840	transmembrane signaling receptor activity
CLSAP_RS03875	COG3620	sequence-specific DNA binding
CLSAP_RS04000	COG3299	homolog of phage Mu protein gp47
CLSAP_RS04050	COG3409	Peptidoglycan-binding domain 1 protein
CLSAP_RS04050	COG5632	N-Acetylmuramoyl-L-alanine amidase
CLSAP_RS04065	COG3628	GPW Gp25 family protein
CLSAP_RS04070	COG3299	homolog of phage Mu protein gp47
CLSAP_RS04110	COG3328	transposase activity
CLSAP_RS04115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLSAP_RS04120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLSAP_RS04125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLSAP_RS04130	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLSAP_RS04135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLSAP_RS04140	COG0165	Argininosuccinate lyase
CLSAP_RS04145	COG0137	argininosuccinate synthase activity
CLSAP_RS04155	COG2323	membrane
CLSAP_RS04165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLSAP_RS04170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CLSAP_RS04175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLSAP_RS04185	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLSAP_RS04210	COG3875	lactate racemase activity
CLSAP_RS04220	COG2207	Transcriptional regulator
CLSAP_RS04230	COG0577	efflux transmembrane transporter activity
CLSAP_RS04235	COG1136	(ABC) transporter
CLSAP_RS04235	COG0577	efflux transmembrane transporter activity
CLSAP_RS04240	COG5002	protein histidine kinase activity
CLSAP_RS04240	COG5000	phosphorelay sensor kinase activity
CLSAP_RS04245	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS04250	COG0110	maltose O-acetyltransferase activity
CLSAP_RS04260	COG2207	Transcriptional regulator
CLSAP_RS04260	COG4753	response regulator
CLSAP_RS04265	COG2972	Histidine kinase
CLSAP_RS04285	COG1874	Beta-galactosidase
CLSAP_RS04290	COG1609	Transcriptional regulator
CLSAP_RS04295	COG0840	transmembrane signaling receptor activity
CLSAP_RS04295	COG5278	phosphoserine phosphatase activity
CLSAP_RS04300	COG1760	l-serine dehydratase
CLSAP_RS04305	COG1760	l-serine dehydratase
CLSAP_RS04310	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS04315	COG5002	protein histidine kinase activity
CLSAP_RS04325	COG0348	domain, Protein
CLSAP_RS04335	COG0351	phosphomethylpyrimidine kinase
CLSAP_RS04345	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CLSAP_RS04350	COG0352	thiamine-phosphate diphosphorylase activity
CLSAP_RS04360	COG0426	domain, Protein
CLSAP_RS04365	COG2264	protein methyltransferase activity
CLSAP_RS04370	COG0426	domain, Protein
CLSAP_RS04380	COG2610	gluconate transmembrane transporter activity
CLSAP_RS04385	COG1929	Belongs to the glycerate kinase type-1 family
CLSAP_RS04390	COG3835	regulator
CLSAP_RS04395	COG0514	ATP-dependent DNA helicase (RecQ)
CLSAP_RS04400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLSAP_RS04410	COG0613	PHP domain protein
CLSAP_RS04445	COG0531	amino acid
CLSAP_RS04450	COG0833	amino acid
CLSAP_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS04460	COG0765	amino acid transport
CLSAP_RS04470	COG1408	metallophosphoesterase
CLSAP_RS04480	COG1131	(ABC) transporter
CLSAP_RS04485	COG1725	Transcriptional regulator
CLSAP_RS04495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLSAP_RS04505	COG0157	Belongs to the NadC ModD family
CLSAP_RS04535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLSAP_RS04535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLSAP_RS04580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLSAP_RS04580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLSAP_RS04595	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CLSAP_RS04600	COG1067	ATP-dependent peptidase activity
CLSAP_RS04610	COG2172	sigma factor antagonist activity
CLSAP_RS04625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLSAP_RS04635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLSAP_RS04640	COG0658	competence protein
CLSAP_RS04640	COG2333	competence protein COMEC
CLSAP_RS04650	COG0268	Binds directly to 16S ribosomal RNA
CLSAP_RS04655	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLSAP_RS04670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CLSAP_RS04675	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CLSAP_RS04680	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLSAP_RS04690	COG2205	protein histidine kinase activity
CLSAP_RS04695	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS04715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLSAP_RS04720	COG1420	regulation of RNA biosynthetic process
CLSAP_RS04725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLSAP_RS04730	COG0443	Heat shock 70 kDa protein
CLSAP_RS04735	COG0484	heat shock protein binding
CLSAP_RS04740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLSAP_RS04745	COG2264	protein methyltransferase activity
CLSAP_RS04750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLSAP_RS04755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLSAP_RS04760	COG0537	adenosine 5'-monophosphoramidase activity
CLSAP_RS04770	COG1610	YqeY-like protein
CLSAP_RS04790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLSAP_RS04795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLSAP_RS04800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLSAP_RS04815	COG0517	IMP dehydrogenase activity
CLSAP_RS04820	COG0574	Belongs to the PEP-utilizing enzyme family
CLSAP_RS04820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLSAP_RS04830	COG3591	Belongs to the peptidase S1B family
CLSAP_RS04830	COG1864	DNA RNA non-specific endonuclease
CLSAP_RS04835	COG5634	Uncharacterized conserved protein (DUF2278)
CLSAP_RS04855	COG1924	4 iron, 4 sulfur cluster binding
CLSAP_RS04865	COG2814	Major facilitator Superfamily
CLSAP_RS04880	COG2972	Histidine kinase
CLSAP_RS04885	COG4753	response regulator
CLSAP_RS04885	COG2207	Transcriptional regulator
CLSAP_RS04900	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS04920	COG3711	transcriptional antiterminator
CLSAP_RS04925	COG2190	(PTS) system
CLSAP_RS04925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS04925	COG1263	PTS System
CLSAP_RS04950	COG0358	DNA primase activity
CLSAP_RS04955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLSAP_RS04985	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS04990	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS04995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS05005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLSAP_RS05015	COG2080	2 iron, 2 sulfur cluster binding
CLSAP_RS05030	COG1151	hydroxylamine reductase activity
CLSAP_RS05045	COG1404	Belongs to the peptidase S8 family
CLSAP_RS05050	COG3842	ATPase activity
CLSAP_RS05055	COG2508	Transcriptional regulator
CLSAP_RS05065	COG0058	SHG alpha-glucan phosphorylase activity
CLSAP_RS05070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLSAP_RS05075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLSAP_RS05075	COG0551	DNA topoisomerase type I activity
CLSAP_RS05080	COG0723	plastoquinol--plastocyanin reductase activity
CLSAP_RS05080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLSAP_RS05090	COG0004	ammonium transporteR
CLSAP_RS05095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLSAP_RS05100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLSAP_RS05105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLSAP_RS05155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLSAP_RS05160	COG1116	anion transmembrane transporter activity
CLSAP_RS05165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLSAP_RS05190	COG3442	glutamine amidotransferase
CLSAP_RS05195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLSAP_RS05205	COG0826	peptidase U32
CLSAP_RS05210	COG1193	negative regulation of DNA recombination
CLSAP_RS05215	COG1683	Conserved Protein
CLSAP_RS05225	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS05230	COG0477	Major facilitator Superfamily
CLSAP_RS05235	COG3384	dioxygenase
CLSAP_RS05240	COG1846	Transcriptional regulator
CLSAP_RS05245	COG0386	Belongs to the glutathione peroxidase family
CLSAP_RS05250	COG0492	ferredoxin-NADP+ reductase activity
CLSAP_RS05255	COG3118	belongs to the thioredoxin family
CLSAP_RS05270	COG0420	3'-5' exonuclease activity
CLSAP_RS05275	COG0419	ATPase involved in DNA repair
CLSAP_RS05280	COG1151	hydroxylamine reductase activity
CLSAP_RS05285	COG3279	Response regulator of the LytR AlgR family
CLSAP_RS05295	COG4864	UPF0365 protein
CLSAP_RS05305	COG3290	protein histidine kinase activity
CLSAP_RS05310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLSAP_RS05325	COG0728	peptidoglycan biosynthetic process
CLSAP_RS05335	COG0438	transferase activity, transferring glycosyl groups
CLSAP_RS05360	COG0012	GTP binding
CLSAP_RS05370	COG1482	cell wall glycoprotein biosynthetic process
CLSAP_RS05390	COG0540	Belongs to the ATCase OTCase family
CLSAP_RS05415	COG0167	dihydroorotate dehydrogenase activity
CLSAP_RS05420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLSAP_RS05445	COG0039	L-malate dehydrogenase activity
CLSAP_RS05455	COG5434	Belongs to the glycosyl hydrolase 28 family
CLSAP_RS05455	COG4632	Exopolysaccharide biosynthesis protein
CLSAP_RS05465	COG1994	Peptidase M50
CLSAP_RS05480	COG3850	Histidine kinase
CLSAP_RS05480	COG5002	protein histidine kinase activity
CLSAP_RS05485	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS05490	COG0018	arginyl-trna synthetase
CLSAP_RS05495	COG0628	permease
CLSAP_RS05500	COG0778	Nitroreductase
CLSAP_RS05530	COG2155	Conserved Protein
CLSAP_RS05535	COG1522	sequence-specific DNA binding
CLSAP_RS05560	COG0697	spore germination
CLSAP_RS05565	COG0367	asparagine synthase
CLSAP_RS05600	COG1132	(ABC) transporter
CLSAP_RS05610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLSAP_RS05635	COG5002	protein histidine kinase activity
CLSAP_RS05665	COG0765	amino acid transport
CLSAP_RS05670	COG1126	abc transporter atp-binding protein
CLSAP_RS05690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLSAP_RS05695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLSAP_RS05705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLSAP_RS05710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLSAP_RS05715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLSAP_RS05720	COG0138	bifunctional purine biosynthesis protein purh
CLSAP_RS05725	COG0151	Belongs to the GarS family
CLSAP_RS05770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLSAP_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS05790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLSAP_RS05795	COG0511	ligase activity, forming carbon-carbon bonds
CLSAP_RS05800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLSAP_RS05810	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLSAP_RS05815	COG0825	malonyl-CoA metabolic process
CLSAP_RS05830	COG4120	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS05845	COG0489	protein tyrosine kinase activity
CLSAP_RS05850	COG4464	protein tyrosine phosphatase activity
CLSAP_RS05855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLSAP_RS05860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLSAP_RS05890	COG1442	glycosyl transferase family 8
CLSAP_RS05890	COG1216	Glycosyl transferase, family 2
CLSAP_RS05905	COG1216	Glycosyl transferase, family 2
CLSAP_RS05915	COG0577	efflux transmembrane transporter activity
CLSAP_RS05915	COG1136	(ABC) transporter
CLSAP_RS05925	COG1091	dTDP-4-dehydrorhamnose reductase activity
CLSAP_RS05940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLSAP_RS05945	COG1959	2 iron, 2 sulfur cluster binding
CLSAP_RS05955	COG0822	iron-sulfur transferase activity
CLSAP_RS05960	COG0482	sulfurtransferase activity
CLSAP_RS05965	COG1960	acyl-CoA dehydrogenase activity
CLSAP_RS05970	COG0426	domain, Protein
CLSAP_RS05980	COG0628	permease
CLSAP_RS05985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLSAP_RS05990	COG4472	Bacterial protein of unknown function (DUF965)
CLSAP_RS05995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLSAP_RS06005	COG0735	belongs to the Fur family
CLSAP_RS06010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLSAP_RS06015	COG1217	gtp-binding protein TYPA
CLSAP_RS06020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLSAP_RS06025	COG4122	O-methyltransferase activity
CLSAP_RS06030	COG0826	peptidase U32
CLSAP_RS06035	COG0768	penicillin binding
CLSAP_RS06050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLSAP_RS06060	COG1191	sigma factor activity
CLSAP_RS06065	COG1191	sigma factor activity
CLSAP_RS06070	COG1873	PFAM PRC-barrel domain
CLSAP_RS06075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLSAP_RS06080	COG1496	oxidoreductase activity
CLSAP_RS06085	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS06090	COG5002	protein histidine kinase activity
CLSAP_RS06100	COG0573	inorganic phosphate transmembrane transporter activity
CLSAP_RS06105	COG0581	inorganic phosphate transmembrane transporter activity
CLSAP_RS06110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLSAP_RS06115	COG0704	Plays a role in the regulation of phosphate uptake
CLSAP_RS06120	COG0750	zinc metalloprotease
CLSAP_RS06125	COG1160	GTP binding
CLSAP_RS06130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLSAP_RS06135	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLSAP_RS06145	COG1561	YicC-like family, N-terminal region
CLSAP_RS06150	COG2052	Domain of unknown function (DUF370)
CLSAP_RS06160	COG1758	RNA polymerase activity
CLSAP_RS06165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLSAP_RS06170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLSAP_RS06180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLSAP_RS06185	COG2738	Putative neutral zinc metallopeptidase
CLSAP_RS06190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLSAP_RS06190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLSAP_RS06195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLSAP_RS06200	COG0631	protein serine/threonine phosphatase activity
CLSAP_RS06210	COG1162	GTPase activity
CLSAP_RS06215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLSAP_RS06225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLSAP_RS06230	COG1302	Protein conserved in bacteria
CLSAP_RS06235	COG1461	Dihydroxyacetone kinase
CLSAP_RS06240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLSAP_RS06245	COG0742	ribosomal rna small subunit methyltransferase
CLSAP_RS06250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLSAP_RS06265	COG1323	Belongs to the UPF0348 family
CLSAP_RS06270	COG0280	phosphate acetyltransferase
CLSAP_RS06275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLSAP_RS06290	COG0416	fatty acid biosynthetic process
CLSAP_RS06300	COG0571	ribonuclease III activity
CLSAP_RS06315	COG0552	protein localization to endoplasmic reticulum
CLSAP_RS06320	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CLSAP_RS06325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLSAP_RS06330	COG0228	four-way junction DNA binding
CLSAP_RS06340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLSAP_RS06345	COG0336	Belongs to the RNA methyltransferase TrmD family
CLSAP_RS06350	COG0335	large ribosomal subunit rRNA binding
CLSAP_RS06360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLSAP_RS06370	COG0606	chelatase, subunit chli
CLSAP_RS06375	COG0758	DNA mediated transformation
CLSAP_RS06380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLSAP_RS06385	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CLSAP_RS06390	COG0052	Belongs to the universal ribosomal protein uS2 family
CLSAP_RS06415	COG4589	Belongs to the CDS family
CLSAP_RS06420	COG0628	permease
CLSAP_RS06435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLSAP_RS06440	COG0779	Required for maturation of 30S ribosomal subunits
CLSAP_RS06445	COG0195	Participates in both transcription termination and antitermination
CLSAP_RS06450	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CLSAP_RS06460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLSAP_RS06465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLSAP_RS06470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CLSAP_RS06480	COG0196	riboflavin kinase activity
CLSAP_RS06485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLSAP_RS06490	COG1185	polyribonucleotide nucleotidyltransferase activity
CLSAP_RS06495	COG0612	Peptidase, M16
CLSAP_RS06505	COG0527	aspartate kinase activity
CLSAP_RS06510	COG0740	serine-type endopeptidase activity
CLSAP_RS06520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLSAP_RS06525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLSAP_RS06530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLSAP_RS06535	COG1418	mRNA catabolic process
CLSAP_RS06540	COG2359	stage V sporulation protein S
CLSAP_RS06545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS06550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLSAP_RS06575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLSAP_RS06575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLSAP_RS06580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLSAP_RS06590	COG3158	transport of potassium into the cell
CLSAP_RS06595	COG3158	transport of potassium into the cell
CLSAP_RS06600	COG2078	PFAM AMMECR1 domain protein
CLSAP_RS06600	COG3885	ferrous iron binding
CLSAP_RS06605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLSAP_RS06620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLSAP_RS06630	COG1309	transcriptional regulator
CLSAP_RS06635	COG0477	Major facilitator Superfamily
CLSAP_RS06640	COG2945	thiolester hydrolase activity
CLSAP_RS06640	COG0596	Alpha beta hydrolase
CLSAP_RS06675	COG0435	Glutathione S-transferase
CLSAP_RS06680	COG4166	transmembrane transport
CLSAP_RS06685	COG0601	transmembrane transport
CLSAP_RS06690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLSAP_RS06695	COG0444	Belongs to the ABC transporter superfamily
CLSAP_RS06700	COG4608	Belongs to the ABC transporter superfamily
CLSAP_RS06705	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLSAP_RS06715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLSAP_RS06720	COG0435	Glutathione S-transferase
CLSAP_RS06725	COG0435	Glutathione S-transferase
CLSAP_RS06730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS06735	COG0765	amino acid transport
CLSAP_RS06740	COG1126	abc transporter atp-binding protein
CLSAP_RS06745	COG0435	Glutathione S-transferase
CLSAP_RS06750	COG0456	acetyltransferase
CLSAP_RS06755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS06765	COG1473	amidohydrolase
CLSAP_RS06770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS06775	COG0765	amino acid transport
CLSAP_RS06780	COG0765	amino acid transport
CLSAP_RS06785	COG1126	abc transporter atp-binding protein
CLSAP_RS06790	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CLSAP_RS06805	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CLSAP_RS06815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLSAP_RS06820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLSAP_RS06825	COG1116	anion transmembrane transporter activity
CLSAP_RS06830	COG0371	Dehydrogenase
CLSAP_RS06835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLSAP_RS06845	COG0482	sulfurtransferase activity
CLSAP_RS06865	COG2011	ABC-type metal ion transport system permease component
CLSAP_RS06885	COG0626	cystathionine gamma-synthase activity
CLSAP_RS06890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLSAP_RS06905	COG0601	transmembrane transport
CLSAP_RS06910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLSAP_RS06915	COG0444	Belongs to the ABC transporter superfamily
CLSAP_RS06925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLSAP_RS06930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLSAP_RS06935	COG2814	Major facilitator Superfamily
CLSAP_RS06945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLSAP_RS06975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLSAP_RS06980	COG2226	methyltransferase
CLSAP_RS06995	COG3711	transcriptional antiterminator
CLSAP_RS06995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS07000	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS07015	COG2826	transposase and inactivated derivatives, IS30 family
CLSAP_RS07020	COG0667	Aldo Keto reductase
CLSAP_RS07025	COG3963	phosphatidate phosphatase activity
CLSAP_RS07035	COG1705	Flagellar rod assembly protein muramidase FlgJ
CLSAP_RS07040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CLSAP_RS07045	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CLSAP_RS07055	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLSAP_RS07065	COG0406	alpha-ribazole phosphatase activity
CLSAP_RS07075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLSAP_RS07085	COG1492	cobalamin metabolic process
CLSAP_RS07100	COG3437	response regulator, receiver
CLSAP_RS07110	COG0561	phosphatase activity
CLSAP_RS07120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CLSAP_RS07125	COG2706	6-phosphogluconolactonase activity
CLSAP_RS07130	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CLSAP_RS07135	COG3647	Membrane
CLSAP_RS07150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLSAP_RS07155	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLSAP_RS07165	COG0181	hydroxymethylbilane synthase activity
CLSAP_RS07175	COG0113	porphobilinogen synthase activity
CLSAP_RS07180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLSAP_RS07195	COG3507	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS07200	COG5520	Belongs to the glycosyl hydrolase 30 family
CLSAP_RS07205	COG3693	PFAM glycoside hydrolase, family 10
CLSAP_RS07210	COG3693	PFAM glycoside hydrolase, family 10
CLSAP_RS07210	COG3509	depolymerase
CLSAP_RS07215	COG3693	PFAM glycoside hydrolase, family 10
CLSAP_RS07215	COG3507	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS07215	COG2382	esterase
CLSAP_RS07225	COG0726	polysaccharide deacetylase
CLSAP_RS07245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLSAP_RS07250	COG0083	homoserine kinase activity
CLSAP_RS07255	COG4492	Belongs to the UPF0735 family
CLSAP_RS07260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLSAP_RS07260	COG5297	Belongs to the glycosyl hydrolase family 6
CLSAP_RS07265	COG1253	flavin adenine dinucleotide binding
CLSAP_RS07280	COG1131	(ABC) transporter
CLSAP_RS07290	COG5002	protein histidine kinase activity
CLSAP_RS07295	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS07325	COG3708	Transcriptional regulator
CLSAP_RS07325	COG2207	Transcriptional regulator
CLSAP_RS07330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLSAP_RS07375	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CLSAP_RS07380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLSAP_RS07385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLSAP_RS07390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLSAP_RS07395	COG0131	Imidazoleglycerol-phosphate dehydratase
CLSAP_RS07400	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLSAP_RS07405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLSAP_RS07410	COG0107	imidazoleglycerol-phosphate synthase activity
CLSAP_RS07415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLSAP_RS07420	COG0140	phosphoribosyl-ATP diphosphatase activity
CLSAP_RS07435	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLSAP_RS07445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLSAP_RS07450	COG0470	DNA polymerase III
CLSAP_RS07450	COG1067	ATP-dependent peptidase activity
CLSAP_RS07455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLSAP_RS07460	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLSAP_RS07485	COG0735	belongs to the Fur family
CLSAP_RS07500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLSAP_RS07505	COG0210	DNA helicase
CLSAP_RS07520	COG0849	cell division
CLSAP_RS07525	COG1473	amidohydrolase
CLSAP_RS07530	COG0564	pseudouridine synthase activity
CLSAP_RS07540	COG2244	polysaccharide biosynthetic process
CLSAP_RS07545	COG0840	transmembrane signaling receptor activity
CLSAP_RS07575	COG0484	heat shock protein binding
CLSAP_RS07735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLSAP_RS07760	COG0789	Transcriptional regulator
CLSAP_RS07760	COG4978	Transcriptional regulator
CLSAP_RS07785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLSAP_RS07795	COG1410	methionine synthase
CLSAP_RS07795	COG0646	methionine synthase
CLSAP_RS07800	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLSAP_RS07805	COG3866	Pectate lyase
CLSAP_RS07820	COG5002	protein histidine kinase activity
CLSAP_RS07825	COG0784	Response regulator, receiver
CLSAP_RS07835	COG1126	abc transporter atp-binding protein
CLSAP_RS07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS07845	COG0765	amino acid transport
CLSAP_RS07850	COG0765	amino acid transport
CLSAP_RS07860	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS07865	COG2205	protein histidine kinase activity
CLSAP_RS07875	COG1136	(ABC) transporter
CLSAP_RS07880	COG0577	efflux transmembrane transporter activity
CLSAP_RS07890	COG3437	response regulator, receiver
CLSAP_RS07890	COG0784	Response regulator, receiver
CLSAP_RS07930	COG0612	Peptidase, M16
CLSAP_RS07940	COG3655	Transcriptional regulator
CLSAP_RS07950	COG1982	Orn Lys Arg decarboxylase major
CLSAP_RS07955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLSAP_RS07960	COG0542	response to heat
CLSAP_RS07970	COG1522	sequence-specific DNA binding
CLSAP_RS07975	COG0436	Aminotransferase
CLSAP_RS07985	COG1744	ABC transporter substrate-binding protein PnrA-like
CLSAP_RS07995	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS08000	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS08010	COG0295	cytidine deaminase activity
CLSAP_RS08015	COG0813	purine-nucleoside phosphorylase activity
CLSAP_RS08045	COG2755	lipolytic protein G-D-S-L family
CLSAP_RS08060	COG3437	response regulator, receiver
CLSAP_RS08075	COG1523	belongs to the glycosyl hydrolase 13 family
CLSAP_RS08085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLSAP_RS08090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLSAP_RS08095	COG0789	Transcriptional regulator
CLSAP_RS08105	COG0717	Belongs to the dCTP deaminase family
CLSAP_RS08110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLSAP_RS08115	COG0071	Belongs to the small heat shock protein (HSP20) family
CLSAP_RS08135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLSAP_RS08145	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CLSAP_RS08165	COG0531	amino acid
CLSAP_RS08170	COG0531	amino acid
CLSAP_RS08175	COG4086	secreted protein
CLSAP_RS08180	COG1959	2 iron, 2 sulfur cluster binding
CLSAP_RS08185	COG0840	transmembrane signaling receptor activity
CLSAP_RS08215	COG2239	Acts as a magnesium transporter
CLSAP_RS08220	COG3634	alkyl hydroperoxide reductase activity
CLSAP_RS08235	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS08240	COG5002	protein histidine kinase activity
CLSAP_RS08305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLSAP_RS08310	COG0730	response to heat
CLSAP_RS08315	COG0183	Belongs to the thiolase family
CLSAP_RS08320	COG0840	transmembrane signaling receptor activity
CLSAP_RS08330	COG0785	Cytochrome C biogenesis protein
CLSAP_RS08335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLSAP_RS08340	COG0583	DNA-binding transcription factor activity
CLSAP_RS08345	COG1053	succinate dehydrogenase
CLSAP_RS08360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS08360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS08360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS08360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS08365	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS08370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS08375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS08380	COG3250	beta-galactosidase activity
CLSAP_RS08385	COG0840	transmembrane signaling receptor activity
CLSAP_RS08390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLSAP_RS08395	COG0626	cystathionine gamma-synthase activity
CLSAP_RS08400	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS08405	COG1312	Catalyzes the dehydration of D-mannonate
CLSAP_RS08410	COG1904	glucuronate isomerase
CLSAP_RS08415	COG0642	Histidine kinase
CLSAP_RS08415	COG5002	protein histidine kinase activity
CLSAP_RS08420	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS08430	COG1183	phosphatidylcholine synthase activity
CLSAP_RS08435	COG0628	permease
CLSAP_RS08445	COG1132	(ABC) transporter
CLSAP_RS08455	COG0671	phosphoesterase, PA-phosphatase related
CLSAP_RS08475	COG1733	regulation of RNA biosynthetic process
CLSAP_RS08505	COG1484	DNA-dependent DNA replication
CLSAP_RS08510	COG2002	toxin-antitoxin pair type II binding
CLSAP_RS08525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLSAP_RS08530	COG1959	2 iron, 2 sulfur cluster binding
CLSAP_RS08590	COG3706	GGDEF domain
CLSAP_RS08610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLSAP_RS08635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLSAP_RS08640	COG1566	PFAM secretion protein HlyD family protein
CLSAP_RS08645	COG2814	Major facilitator Superfamily
CLSAP_RS08675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLSAP_RS08685	COG0789	Transcriptional regulator
CLSAP_RS08720	COG1733	regulation of RNA biosynthetic process
CLSAP_RS08745	COG1733	regulation of RNA biosynthetic process
CLSAP_RS08755	COG1309	transcriptional regulator
CLSAP_RS08765	COG0596	Alpha beta hydrolase
CLSAP_RS08770	COG1846	Transcriptional regulator
CLSAP_RS08775	COG0534	Mate efflux family protein
CLSAP_RS08780	COG0640	Transcriptional regulator
CLSAP_RS08790	COG1132	(ABC) transporter
CLSAP_RS08795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLSAP_RS08820	COG4447	cellulose binding
CLSAP_RS08820	COG4733	cellulase activity
CLSAP_RS08835	COG4221	oxidoreductase activity
CLSAP_RS08875	COG2267	carboxylic ester hydrolase activity
CLSAP_RS08940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS08960	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLSAP_RS08965	COG1418	mRNA catabolic process
CLSAP_RS08970	COG3708	Transcriptional regulator
CLSAP_RS08970	COG2207	Transcriptional regulator
CLSAP_RS08980	COG2814	Major facilitator Superfamily
CLSAP_RS08990	COG1309	transcriptional regulator
CLSAP_RS08995	COG0778	Nitroreductase
CLSAP_RS09005	COG4221	oxidoreductase activity
CLSAP_RS09005	COG3321	synthase
CLSAP_RS09005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLSAP_RS09005	COG0604	alcohol dehydrogenase
CLSAP_RS09010	COG1309	transcriptional regulator
CLSAP_RS09040	COG1819	glycosyl
CLSAP_RS09070	COG1846	Transcriptional regulator
CLSAP_RS09095	COG1309	transcriptional regulator
CLSAP_RS09105	COG0789	Transcriptional regulator
CLSAP_RS09130	COG1304	FMN binding
CLSAP_RS09135	COG1733	regulation of RNA biosynthetic process
CLSAP_RS09145	COG0183	Belongs to the thiolase family
CLSAP_RS09150	COG1733	regulation of RNA biosynthetic process
CLSAP_RS09165	COG0583	DNA-binding transcription factor activity
CLSAP_RS09170	COG0183	Belongs to the thiolase family
CLSAP_RS09180	COG1609	Transcriptional regulator
CLSAP_RS09185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS09185	COG1263	PTS System
CLSAP_RS09190	COG1653	transport
CLSAP_RS09195	COG1175	transmembrane transport
CLSAP_RS09205	COG0366	Alpha amylase catalytic
CLSAP_RS09215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLSAP_RS09220	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS09220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS09225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS09225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS09230	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS09230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS09235	COG3715	PTS system
CLSAP_RS09240	COG3716	PTS system mannose fructose sorbose family IID component
CLSAP_RS09245	COG5492	domain, Protein
CLSAP_RS09245	COG1621	beta-fructofuranosidase activity
CLSAP_RS09245	COG3583	domain protein
CLSAP_RS09250	COG1846	Transcriptional regulator
CLSAP_RS09265	COG1309	transcriptional regulator
CLSAP_RS09280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLSAP_RS09285	COG1309	transcriptional regulator
CLSAP_RS09290	COG0778	Nitroreductase
CLSAP_RS09295	COG0456	acetyltransferase
CLSAP_RS09300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLSAP_RS09305	COG1846	Transcriptional regulator
CLSAP_RS09310	COG2207	Transcriptional regulator
CLSAP_RS09320	COG0561	phosphatase activity
CLSAP_RS09380	COG3963	phosphatidate phosphatase activity
CLSAP_RS09400	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS09410	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS09430	COG3829	transcription factor binding
CLSAP_RS09430	COG3290	protein histidine kinase activity
CLSAP_RS09440	COG2610	gluconate transmembrane transporter activity
CLSAP_RS09445	COG2030	dehydratase
CLSAP_RS09450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLSAP_RS09460	COG1960	acyl-CoA dehydrogenase activity
CLSAP_RS09465	COG2086	electron transfer activity
CLSAP_RS09475	COG0840	transmembrane signaling receptor activity
CLSAP_RS09480	COG1309	transcriptional regulator
CLSAP_RS09485	COG0574	Belongs to the PEP-utilizing enzyme family
CLSAP_RS09485	COG3848	Pyruvate phosphate dikinase
CLSAP_RS09490	COG1378	Sugar-specific transcriptional regulator TrmB
CLSAP_RS09500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLSAP_RS09510	COG0488	(ABC) transporter
CLSAP_RS09530	COG3507	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS09550	COG3433	isochorismatase activity
CLSAP_RS09550	COG2226	methyltransferase
CLSAP_RS09550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLSAP_RS09575	COG2226	methyltransferase
CLSAP_RS09575	COG3433	isochorismatase activity
CLSAP_RS09575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLSAP_RS09595	COG1129	ABC transporter
CLSAP_RS09605	COG2375	cellular response to nickel ion
CLSAP_RS09605	COG1132	(ABC) transporter
CLSAP_RS09610	COG1132	(ABC) transporter
CLSAP_RS09625	COG0601	transmembrane transport
CLSAP_RS09635	COG0444	Belongs to the ABC transporter superfamily
CLSAP_RS09640	COG4608	Belongs to the ABC transporter superfamily
CLSAP_RS09650	COG0657	acetylesterase activity
CLSAP_RS09655	COG0583	DNA-binding transcription factor activity
CLSAP_RS09695	COG5520	Belongs to the glycosyl hydrolase 30 family
CLSAP_RS09695	COG3291	Pkd domain containing protein
CLSAP_RS09695	COG4447	cellulose binding
CLSAP_RS09705	COG1012	belongs to the aldehyde dehydrogenase family
CLSAP_RS09710	COG0280	phosphate acetyltransferase
CLSAP_RS09735	COG2213	PTS system mannitol-specific
CLSAP_RS09745	COG3711	transcriptional antiterminator
CLSAP_RS09750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS09785	COG1063	alcohol dehydrogenase
CLSAP_RS09800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLSAP_RS09805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLSAP_RS09810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLSAP_RS09960	COG2076	Multidrug Resistance protein
CLSAP_RS09970	COG2703	oxygen carrier activity
CLSAP_RS09975	COG2267	carboxylic ester hydrolase activity
CLSAP_RS09980	COG2703	oxygen carrier activity
CLSAP_RS09995	COG1063	alcohol dehydrogenase
CLSAP_RS10005	COG0697	spore germination
CLSAP_RS10010	COG0477	Major facilitator Superfamily
CLSAP_RS10015	COG1846	Transcriptional regulator
CLSAP_RS10020	COG1335	isochorismatase
CLSAP_RS10025	COG1522	sequence-specific DNA binding
CLSAP_RS10045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLSAP_RS10050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLSAP_RS10070	COG2207	Transcriptional regulator
CLSAP_RS10080	COG4975	Glucose uptake
CLSAP_RS10095	COG1175	transmembrane transport
CLSAP_RS10100	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS10105	COG3250	beta-galactosidase activity
CLSAP_RS10115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS10115	COG2190	(PTS) system
CLSAP_RS10115	COG1263	PTS System
CLSAP_RS10120	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS10125	COG3711	transcriptional antiterminator
CLSAP_RS10170	COG5002	protein histidine kinase activity
CLSAP_RS10180	COG4555	ABC transporter
CLSAP_RS10200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLSAP_RS10225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS10225	COG2199	diguanylate cyclase activity
CLSAP_RS10235	COG0840	transmembrane signaling receptor activity
CLSAP_RS10240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLSAP_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS10265	COG3246	L-lysine catabolic process to acetate
CLSAP_RS10270	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLSAP_RS10275	COG3290	protein histidine kinase activity
CLSAP_RS10275	COG3829	transcription factor binding
CLSAP_RS10295	COG1733	regulation of RNA biosynthetic process
CLSAP_RS10300	COG1902	pentaerythritol trinitrate reductase activity
CLSAP_RS10310	COG0583	DNA-binding transcription factor activity
CLSAP_RS10315	COG0702	epimerase
CLSAP_RS10320	COG0840	transmembrane signaling receptor activity
CLSAP_RS10325	COG0640	Transcriptional regulator
CLSAP_RS10355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLSAP_RS10365	COG0693	protein deglycase activity
CLSAP_RS10375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS10390	COG1595	DNA-templated transcription, initiation
CLSAP_RS10420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS10430	COG2207	Transcriptional regulator
CLSAP_RS10440	COG1175	transmembrane transport
CLSAP_RS10445	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS10475	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLSAP_RS10480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLSAP_RS10505	COG0561	phosphatase activity
CLSAP_RS10510	COG1846	Transcriptional regulator
CLSAP_RS10510	COG1940	carbohydrate kinase activity
CLSAP_RS10525	COG0110	maltose O-acetyltransferase activity
CLSAP_RS10535	COG4978	Transcriptional regulator
CLSAP_RS10535	COG0789	Transcriptional regulator
CLSAP_RS10540	COG2076	Multidrug Resistance protein
CLSAP_RS10545	COG2076	Multidrug Resistance protein
CLSAP_RS10555	COG1733	regulation of RNA biosynthetic process
CLSAP_RS10560	COG1408	metallophosphoesterase
CLSAP_RS10565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLSAP_RS10570	COG0697	spore germination
CLSAP_RS10575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS10575	COG1263	PTS System
CLSAP_RS10575	COG2190	(PTS) system
CLSAP_RS10580	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS10585	COG3711	transcriptional antiterminator
CLSAP_RS10590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLSAP_RS10600	COG5566	PFAM Mor transcription activator
CLSAP_RS10605	COG0243	molybdopterin cofactor binding
CLSAP_RS10610	COG0437	4 iron, 4 sulfur cluster binding
CLSAP_RS10615	COG3381	protein complex oligomerization
CLSAP_RS10620	COG0840	transmembrane signaling receptor activity
CLSAP_RS10645	COG2207	Transcriptional regulator
CLSAP_RS10645	COG4753	response regulator
CLSAP_RS10655	COG4213	ABC transporter substrate-binding protein
CLSAP_RS10660	COG1129	ABC transporter
CLSAP_RS10665	COG4214	carbohydrate transport
CLSAP_RS10670	COG0840	transmembrane signaling receptor activity
CLSAP_RS10680	COG1070	Carbohydrate kinase
CLSAP_RS10710	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLSAP_RS10715	COG1733	regulation of RNA biosynthetic process
CLSAP_RS10720	COG1846	Transcriptional regulator
CLSAP_RS10735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLSAP_RS10740	COG0789	Transcriptional regulator
CLSAP_RS10760	COG0778	Nitroreductase
CLSAP_RS10790	COG1396	sequence-specific DNA binding
CLSAP_RS10795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CLSAP_RS10800	COG1687	branched-chain amino acid
CLSAP_RS10815	COG5002	protein histidine kinase activity
CLSAP_RS10820	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS10825	COG0840	transmembrane signaling receptor activity
CLSAP_RS10835	COG0519	Catalyzes the synthesis of GMP from XMP
CLSAP_RS10840	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS10915	COG1410	methionine synthase
CLSAP_RS10915	COG0646	methionine synthase
CLSAP_RS10930	COG1113	amino acid transport
CLSAP_RS10945	COG2188	Transcriptional regulator
CLSAP_RS10950	COG1263	PTS System
CLSAP_RS10950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS10955	COG0366	Alpha amylase catalytic
CLSAP_RS10975	COG2201	protein-glutamate methylesterase activity
CLSAP_RS10990	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CLSAP_RS10995	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CLSAP_RS11010	COG0523	cobalamin synthesis protein
CLSAP_RS11045	COG1132	(ABC) transporter
CLSAP_RS11050	COG1132	(ABC) transporter
CLSAP_RS11055	COG3584	3D domain protein
CLSAP_RS11055	COG1388	LysM domain
CLSAP_RS11065	COG2199	diguanylate cyclase activity
CLSAP_RS11065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS11070	COG0517	IMP dehydrogenase activity
CLSAP_RS11080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLSAP_RS11100	COG1592	Rubrerythrin
CLSAP_RS11105	COG2033	superoxide reductase activity
CLSAP_RS11115	COG2204	response regulator
CLSAP_RS11130	COG3852	Histidine kinase
CLSAP_RS11140	COG0778	Nitroreductase
CLSAP_RS11145	COG1393	Belongs to the ArsC family
CLSAP_RS11150	COG0443	Heat shock 70 kDa protein
CLSAP_RS11170	COG1164	Oligoendopeptidase f
CLSAP_RS11185	COG0653	protein targeting
CLSAP_RS11190	COG5002	protein histidine kinase activity
CLSAP_RS11200	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS11205	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS11230	COG1268	BioY protein
CLSAP_RS11245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLSAP_RS11265	COG4191	Histidine kinase
CLSAP_RS11270	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLSAP_RS11280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLSAP_RS11285	COG0791	NLP P60 protein
CLSAP_RS11295	COG1550	Protein conserved in bacteria
CLSAP_RS11300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLSAP_RS11315	COG3706	GGDEF domain
CLSAP_RS11345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLSAP_RS11360	COG0586	Pfam SNARE associated Golgi protein
CLSAP_RS11385	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS11390	COG5002	protein histidine kinase activity
CLSAP_RS11390	COG3850	Histidine kinase
CLSAP_RS11405	COG0443	Heat shock 70 kDa protein
CLSAP_RS11420	COG1349	DNA-binding transcription factor activity
CLSAP_RS11425	COG0561	phosphatase activity
CLSAP_RS11440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLSAP_RS11445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLSAP_RS11460	COG0583	DNA-binding transcription factor activity
CLSAP_RS11465	COG1335	isochorismatase
CLSAP_RS11505	COG5002	protein histidine kinase activity
CLSAP_RS11510	COG2040	homocysteine
CLSAP_RS11515	COG4305	rare lipoprotein A
CLSAP_RS11525	COG0833	amino acid
CLSAP_RS11540	COG0215	cysteine-tRNA ligase activity
CLSAP_RS11545	COG4129	membrane
CLSAP_RS11550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLSAP_RS11555	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS11570	COG0789	Transcriptional regulator
CLSAP_RS11580	COG1592	Rubrerythrin
CLSAP_RS11580	COG1773	rubredoxin
CLSAP_RS11595	COG2357	RelA SpoT domain protein
CLSAP_RS11610	COG0432	Pfam Uncharacterised protein family UPF0047
CLSAP_RS11625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLSAP_RS11630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLSAP_RS11640	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS11650	COG1131	(ABC) transporter
CLSAP_RS11675	COG1376	ErfK ybiS ycfS ynhG family protein
CLSAP_RS11680	COG2315	Protein conserved in bacteria
CLSAP_RS11705	COG0632	four-way junction helicase activity
CLSAP_RS11710	COG2255	four-way junction helicase activity
CLSAP_RS11715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLSAP_RS11735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLSAP_RS11740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLSAP_RS11745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLSAP_RS11745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CLSAP_RS11750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLSAP_RS11755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLSAP_RS11760	COG1490	D-aminoacyl-tRNA deacylase activity
CLSAP_RS11765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLSAP_RS11770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLSAP_RS11780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLSAP_RS11785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLSAP_RS11790	COG1811	Na channel or pump
CLSAP_RS11795	COG0250	Participates in transcription elongation, termination and antitermination
CLSAP_RS11815	COG0438	transferase activity, transferring glycosyl groups
CLSAP_RS11815	COG0297	glycogen (starch) synthase activity
CLSAP_RS11855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLSAP_RS11860	COG3944	biosynthesis protein
CLSAP_RS11865	COG0489	protein tyrosine kinase activity
CLSAP_RS11875	COG0489	protein tyrosine kinase activity
CLSAP_RS11915	COG0460	homoserine dehydrogenase
CLSAP_RS11930	COG0572	uridine kinase
CLSAP_RS11940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLSAP_RS11950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLSAP_RS11975	COG1733	regulation of RNA biosynthetic process
CLSAP_RS11980	COG0488	(ABC) transporter
CLSAP_RS12005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLSAP_RS12010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLSAP_RS12015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLSAP_RS12025	COG2001	Belongs to the MraZ family
CLSAP_RS12030	COG0275	rRNA processing
CLSAP_RS12040	COG0768	penicillin binding
CLSAP_RS12045	COG0768	penicillin binding
CLSAP_RS12055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLSAP_RS12060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLSAP_RS12065	COG0772	Belongs to the SEDS family
CLSAP_RS12080	COG3856	small basic protein
CLSAP_RS12090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLSAP_RS12095	COG1799	cell septum assembly
CLSAP_RS12110	COG3599	regulation of cell shape
CLSAP_RS12120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLSAP_RS12125	COG0564	pseudouridine synthase activity
CLSAP_RS12130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLSAP_RS12135	COG0116	Belongs to the methyltransferase superfamily
CLSAP_RS12160	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CLSAP_RS12160	COG3976	FMN-binding domain protein
CLSAP_RS12175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLSAP_RS12230	COG3854	ATPases associated with a variety of cellular activities
CLSAP_RS12270	COG1302	Protein conserved in bacteria
CLSAP_RS12275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLSAP_RS12280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLSAP_RS12285	COG1570	exodeoxyribonuclease VII activity
CLSAP_RS12290	COG1722	exodeoxyribonuclease VII activity
CLSAP_RS12295	COG0142	geranyltranstransferase activity
CLSAP_RS12300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLSAP_RS12305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CLSAP_RS12310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLSAP_RS12315	COG1438	arginine binding
CLSAP_RS12320	COG0497	DNA recombination
CLSAP_RS12325	COG0750	zinc metalloprotease
CLSAP_RS12330	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS12420	COG5492	domain, Protein
CLSAP_RS12435	COG0840	transmembrane signaling receptor activity
CLSAP_RS12445	COG2233	PERMEase
CLSAP_RS12465	COG0406	alpha-ribazole phosphatase activity
CLSAP_RS12470	COG0464	growth
CLSAP_RS12490	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLSAP_RS12490	COG0493	'glutamate synthase
CLSAP_RS12510	COG0463	Glycosyl transferase, family 2
CLSAP_RS12515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLSAP_RS12550	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS12555	COG5002	protein histidine kinase activity
CLSAP_RS12580	COG0534	Mate efflux family protein
CLSAP_RS12605	COG2966	Psort location CytoplasmicMembrane, score
CLSAP_RS12610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLSAP_RS12630	COG0840	transmembrane signaling receptor activity
CLSAP_RS12665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLSAP_RS12675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLSAP_RS12715	COG1686	Belongs to the peptidase S11 family
CLSAP_RS12725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLSAP_RS12730	COG3874	Sporulation protein YtfJ
CLSAP_RS12740	COG1686	Belongs to the peptidase S11 family
CLSAP_RS12750	COG0445	tRNA wobble uridine modification
CLSAP_RS12760	COG1187	pseudouridine synthase activity
CLSAP_RS12770	COG0617	tRNA 3'-terminal CCA addition
CLSAP_RS12780	COG0840	transmembrane signaling receptor activity
CLSAP_RS12785	COG1116	anion transmembrane transporter activity
CLSAP_RS12790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLSAP_RS12795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLSAP_RS12800	COG1073	alpha beta
CLSAP_RS12805	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS12805	COG2207	Transcriptional regulator
CLSAP_RS12810	COG0697	spore germination
CLSAP_RS12835	COG0840	transmembrane signaling receptor activity
CLSAP_RS12845	COG4191	Histidine kinase
CLSAP_RS12850	COG3852	Histidine kinase
CLSAP_RS12865	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLSAP_RS12875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLSAP_RS12885	COG1575	Belongs to the MenA family. Type 1 subfamily
CLSAP_RS12890	COG1595	DNA-templated transcription, initiation
CLSAP_RS12905	COG2217	Heavy metal translocating P-type atpase
CLSAP_RS12960	COG2738	Putative neutral zinc metallopeptidase
CLSAP_RS12965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLSAP_RS12970	COG2733	membrane
CLSAP_RS12975	COG2733	membrane
CLSAP_RS13015	COG2197	response regulator
CLSAP_RS13020	COG0347	Belongs to the P(II) protein family
CLSAP_RS13030	COG3842	ATPase activity
CLSAP_RS13035	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLSAP_RS13040	COG1177	transmembrane transport
CLSAP_RS13045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLSAP_RS13050	COG1012	belongs to the aldehyde dehydrogenase family
CLSAP_RS13055	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS13055	COG2199	diguanylate cyclase activity
CLSAP_RS13060	COG0840	transmembrane signaling receptor activity
CLSAP_RS13090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLSAP_RS13095	COG0511	ligase activity, forming carbon-carbon bonds
CLSAP_RS13100	COG0439	Biotin carboxylase
CLSAP_RS13105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLSAP_RS13110	COG0825	malonyl-CoA metabolic process
CLSAP_RS13140	COG2909	trisaccharide binding
CLSAP_RS13150	COG1454	alcohol dehydrogenase
CLSAP_RS13155	COG2826	transposase and inactivated derivatives, IS30 family
CLSAP_RS13160	COG0789	Transcriptional regulator
CLSAP_RS13165	COG0477	Major facilitator Superfamily
CLSAP_RS13185	COG1111	helicase
CLSAP_RS13185	COG1205	dead DEAH box helicase
CLSAP_RS13190	COG0210	DNA helicase
CLSAP_RS13195	COG2703	oxygen carrier activity
CLSAP_RS13210	COG1012	belongs to the aldehyde dehydrogenase family
CLSAP_RS13220	COG2207	Transcriptional regulator
CLSAP_RS13220	COG3708	Transcriptional regulator
CLSAP_RS13235	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS13240	COG3850	Histidine kinase
CLSAP_RS13240	COG5002	protein histidine kinase activity
CLSAP_RS13245	COG4989	oxidoreductase activity
CLSAP_RS13255	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS13260	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS13270	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLSAP_RS13300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLSAP_RS13310	COG4208	sulfate ABC transporter
CLSAP_RS13315	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLSAP_RS13330	COG0175	sulfate reduction
CLSAP_RS13335	COG2895	sulfate adenylyltransferase (ATP) activity
CLSAP_RS13340	COG2002	toxin-antitoxin pair type II binding
CLSAP_RS13370	COG2226	methyltransferase
CLSAP_RS13375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLSAP_RS13380	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS13390	COG3290	protein histidine kinase activity
CLSAP_RS13390	COG3829	transcription factor binding
CLSAP_RS13405	COG3394	polysaccharide catabolic process
CLSAP_RS13410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS13425	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLSAP_RS13455	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS13460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLSAP_RS13465	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS13485	COG1846	Transcriptional regulator
CLSAP_RS13490	COG1289	transmembrane transporter activity
CLSAP_RS13520	COG0243	molybdopterin cofactor binding
CLSAP_RS13535	COG0746	molybdenum cofactor guanylyltransferase activity
CLSAP_RS13545	COG0303	'Molybdopterin
CLSAP_RS13570	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLSAP_RS13580	COG2826	transposase and inactivated derivatives, IS30 family
CLSAP_RS13585	COG0667	Aldo Keto reductase
CLSAP_RS13590	COG0310	cobalt ion transport
CLSAP_RS13600	COG1122	ATPase activity
CLSAP_RS13605	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CLSAP_RS13610	COG1606	tRNA processing
CLSAP_RS13615	COG1691	(AIR) carboxylase
CLSAP_RS13620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLSAP_RS13625	COG1234	tRNA 3'-trailer cleavage
CLSAP_RS13635	COG0488	(ABC) transporter
CLSAP_RS13660	COG5002	protein histidine kinase activity
CLSAP_RS13685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLSAP_RS13700	COG1959	2 iron, 2 sulfur cluster binding
CLSAP_RS13710	COG0512	Glutamine amidotransferase of anthranilate synthase
CLSAP_RS13710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLSAP_RS13715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLSAP_RS13720	COG0134	indole-3-glycerol-phosphate synthase activity
CLSAP_RS13725	COG0135	phosphoribosylanthranilate isomerase activity
CLSAP_RS13730	COG0133	tryptophan synthase activity
CLSAP_RS13735	COG0159	tryptophan synthase activity
CLSAP_RS13750	COG0583	DNA-binding transcription factor activity
CLSAP_RS13765	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS13785	COG3585	molybdate ion transport
CLSAP_RS13790	COG3842	ATPase activity
CLSAP_RS13795	COG4149	molybdate abc transporter
CLSAP_RS13800	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLSAP_RS13805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLSAP_RS13810	COG1120	ATPase activity
CLSAP_RS13830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLSAP_RS13840	COG1910	domain protein
CLSAP_RS13865	COG0347	Belongs to the P(II) protein family
CLSAP_RS13905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLSAP_RS13905	COG1199	ATP-dependent helicase activity
CLSAP_RS13925	COG3546	catalase activity
CLSAP_RS13975	COG3935	DnaD domain protein
CLSAP_RS13980	COG1191	sigma factor activity
CLSAP_RS14020	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS14065	COG3728	DNA packaging
CLSAP_RS14065	COG5484	DNA packaging
CLSAP_RS14235	COG5492	domain, Protein
CLSAP_RS14265	COG0084	hydrolase, TatD family'
CLSAP_RS14270	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CLSAP_RS14365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CLSAP_RS14455	COG2962	Rard protein
CLSAP_RS14460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CLSAP_RS14465	COG2267	carboxylic ester hydrolase activity
CLSAP_RS14485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLSAP_RS14505	COG0519	Catalyzes the synthesis of GMP from XMP
CLSAP_RS14530	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS14540	COG0726	polysaccharide deacetylase
CLSAP_RS14580	COG0519	Catalyzes the synthesis of GMP from XMP
CLSAP_RS14585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLSAP_RS14590	COG3546	catalase activity
CLSAP_RS14620	COG1056	cytidyltransferase-related domain
CLSAP_RS14620	COG1051	belongs to the nudix hydrolase family
CLSAP_RS14640	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLSAP_RS14650	COG0375	protein maturation
CLSAP_RS14655	COG0277	FAD linked oxidase domain protein
CLSAP_RS14675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLSAP_RS14695	COG5002	protein histidine kinase activity
CLSAP_RS14710	COG2267	carboxylic ester hydrolase activity
CLSAP_RS14715	COG0477	Major facilitator Superfamily
CLSAP_RS14735	COG0017	Asparaginyl-tRNA synthetase
CLSAP_RS14740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLSAP_RS14745	COG0154	amidase activity
CLSAP_RS14750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLSAP_RS14760	COG0440	acetolactate synthase activity
CLSAP_RS14765	COG0028	Belongs to the TPP enzyme family
CLSAP_RS14770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLSAP_RS14775	COG0488	(ABC) transporter
CLSAP_RS14790	COG1285	pathogenesis
CLSAP_RS14805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLSAP_RS14810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLSAP_RS14815	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CLSAP_RS14835	COG0561	phosphatase activity
CLSAP_RS14840	COG2207	Transcriptional regulator
CLSAP_RS14845	COG2211	Major facilitator Superfamily
CLSAP_RS14850	COG3408	Glycogen debranching enzyme
CLSAP_RS14860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLSAP_RS14865	COG0390	transport system, permease component
CLSAP_RS14870	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CLSAP_RS14880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLSAP_RS14890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLSAP_RS14900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLSAP_RS14905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLSAP_RS14910	COG1923	regulation of RNA biosynthetic process
CLSAP_RS14915	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CLSAP_RS14935	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS14940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLSAP_RS14945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLSAP_RS14950	COG0456	acetyltransferase
CLSAP_RS14975	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS14995	COG0494	nUDIX hydrolase
CLSAP_RS15000	COG0539	negative regulation of cytoplasmic translation
CLSAP_RS15000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLSAP_RS15005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLSAP_RS15010	COG2081	HI0933 family
CLSAP_RS15015	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLSAP_RS15020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLSAP_RS15025	COG0302	gtp cyclohydrolase
CLSAP_RS15030	COG0602	queuosine metabolic process
CLSAP_RS15035	COG0720	synthase
CLSAP_RS15040	COG5521	maltodextrose utilization protein MalA
CLSAP_RS15065	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLSAP_RS15070	COG4948	Mandelate Racemase Muconate Lactonizing
CLSAP_RS15075	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLSAP_RS15080	COG2731	YhcH YjgK YiaL family protein
CLSAP_RS15100	COG0768	penicillin binding
CLSAP_RS15115	COG0598	Magnesium transport protein CorA
CLSAP_RS15125	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS15130	COG1307	EDD domain protein, DegV family
CLSAP_RS15145	COG1404	Belongs to the peptidase S8 family
CLSAP_RS15155	COG0822	iron-sulfur transferase activity
CLSAP_RS15160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLSAP_RS15165	COG0719	Fe-S assembly protein
CLSAP_RS15170	COG0719	Fe-S assembly protein
CLSAP_RS15175	COG0396	ATPase activity
CLSAP_RS15180	COG1959	2 iron, 2 sulfur cluster binding
CLSAP_RS15185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS15185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS15185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS15190	COG1105	Belongs to the carbohydrate kinase PfkB family
CLSAP_RS15195	COG1349	DNA-binding transcription factor activity
CLSAP_RS15210	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CLSAP_RS15215	COG2721	sulfolactate sulfo-lyase activity
CLSAP_RS15220	COG0246	Mannitol dehydrogenase
CLSAP_RS15225	COG0800	Aldolase
CLSAP_RS15230	COG1904	glucuronate isomerase
CLSAP_RS15235	COG2211	Major facilitator Superfamily
CLSAP_RS15245	COG1609	Transcriptional regulator
CLSAP_RS15250	COG0493	'glutamate synthase
CLSAP_RS15255	COG0646	methionine synthase
CLSAP_RS15255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLSAP_RS15265	COG1191	sigma factor activity
CLSAP_RS15275	COG0514	ATP-dependent DNA helicase (RecQ)
CLSAP_RS15280	COG0024	Methionine aminopeptidase
CLSAP_RS15295	COG0697	spore germination
CLSAP_RS15305	COG1132	(ABC) transporter
CLSAP_RS15310	COG1132	(ABC) transporter
CLSAP_RS15320	COG0701	Predicted permease
CLSAP_RS15345	COG1363	Peptidase, m42
CLSAP_RS15350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLSAP_RS15355	COG3759	membrane
CLSAP_RS15365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLSAP_RS15375	COG0577	efflux transmembrane transporter activity
CLSAP_RS15380	COG1136	(ABC) transporter
CLSAP_RS15395	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS15405	COG1187	pseudouridine synthase activity
CLSAP_RS15415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLSAP_RS15420	COG2226	methyltransferase
CLSAP_RS15430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLSAP_RS15435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLSAP_RS15470	COG0346	lactoylglutathione lyase activity
CLSAP_RS15475	COG1595	DNA-templated transcription, initiation
CLSAP_RS15490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLSAP_RS15545	COG0300	oxidoreductase activity
CLSAP_RS15595	COG0667	Aldo Keto reductase
CLSAP_RS15605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLSAP_RS15650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLSAP_RS15695	COG0519	Catalyzes the synthesis of GMP from XMP
CLSAP_RS15700	COG0242	peptide deformylase activity
CLSAP_RS15740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLSAP_RS15790	COG0346	lactoylglutathione lyase activity
CLSAP_RS15825	COG1959	2 iron, 2 sulfur cluster binding
CLSAP_RS15855	COG0384	phenazine biosynthesis protein PhzF
CLSAP_RS15865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CLSAP_RS15890	COG2207	Transcriptional regulator
CLSAP_RS16035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CLSAP_RS16035	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLSAP_RS16040	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLSAP_RS16055	COG3123	guanosine phosphorylase activity
CLSAP_RS16060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS16065	COG0436	Aminotransferase
CLSAP_RS16070	COG2171	N-acyltransferase activity
CLSAP_RS16080	COG0726	polysaccharide deacetylase
CLSAP_RS16110	COG0436	Aminotransferase
CLSAP_RS16115	COG0861	Integral membrane protein TerC family
CLSAP_RS16125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CLSAP_RS16150	COG1846	Transcriptional regulator
CLSAP_RS16160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CLSAP_RS16165	COG0017	Asparaginyl-tRNA synthetase
CLSAP_RS16175	COG0346	lactoylglutathione lyase activity
CLSAP_RS16195	COG0306	phosphate transporter
CLSAP_RS16210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLSAP_RS16230	COG4177	L-phenylalanine transmembrane transporter activity
CLSAP_RS16235	COG0559	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS16260	COG0598	Magnesium transport protein CorA
CLSAP_RS16285	COG1131	(ABC) transporter
CLSAP_RS16290	COG1725	Transcriptional regulator
CLSAP_RS16315	COG2378	regulation of single-species biofilm formation
CLSAP_RS16330	COG2814	Major facilitator Superfamily
CLSAP_RS16340	COG2860	membrane
CLSAP_RS16365	COG0531	amino acid
CLSAP_RS16400	COG0561	phosphatase activity
CLSAP_RS16415	COG5002	protein histidine kinase activity
CLSAP_RS16420	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS16455	COG3590	peptidase
CLSAP_RS16465	COG3973	AAA domain
CLSAP_RS16470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLSAP_RS16475	COG3708	Transcriptional regulator
CLSAP_RS16475	COG2207	Transcriptional regulator
CLSAP_RS16495	COG1253	flavin adenine dinucleotide binding
CLSAP_RS16515	COG4565	transcriptional regulatory protein
CLSAP_RS16520	COG3290	protein histidine kinase activity
CLSAP_RS16530	COG0281	malic enzyme
CLSAP_RS16540	COG5002	protein histidine kinase activity
CLSAP_RS16540	COG3850	Histidine kinase
CLSAP_RS16545	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS16565	COG1136	(ABC) transporter
CLSAP_RS16570	COG0840	transmembrane signaling receptor activity
CLSAP_RS16575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS16580	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS16585	COG4999	Histidine kinase
CLSAP_RS16585	COG2205	protein histidine kinase activity
CLSAP_RS16585	COG3437	response regulator, receiver
CLSAP_RS16585	COG3850	Histidine kinase
CLSAP_RS16590	COG0840	transmembrane signaling receptor activity
CLSAP_RS16595	COG0840	transmembrane signaling receptor activity
CLSAP_RS16600	COG0840	transmembrane signaling receptor activity
CLSAP_RS16605	COG0835	chemotaxis
CLSAP_RS16610	COG0643	Histidine kinase
CLSAP_RS16610	COG2198	Histidine kinase
CLSAP_RS16615	COG2201	protein-glutamate methylesterase activity
CLSAP_RS16625	COG1162	GTPase activity
CLSAP_RS16660	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CLSAP_RS16720	COG0492	ferredoxin-NADP+ reductase activity
CLSAP_RS16735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS16745	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLSAP_RS16750	COG1518	maintenance of DNA repeat elements
CLSAP_RS16915	COG2002	toxin-antitoxin pair type II binding
CLSAP_RS16920	COG1484	DNA-dependent DNA replication
CLSAP_RS16950	COG0582	viral genome integration into host DNA
CLSAP_RS16980	COG0515	serine threonine protein kinase
CLSAP_RS16980	COG2815	serine threonine protein kinase
CLSAP_RS17090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLSAP_RS17130	COG4185	zeta toxin
CLSAP_RS17175	COG1741	Belongs to the pirin family
CLSAP_RS17195	COG0281	malic enzyme
CLSAP_RS17200	COG0493	'glutamate synthase
CLSAP_RS17210	COG0569	domain protein
CLSAP_RS17210	COG2985	domain, Protein
CLSAP_RS17215	COG2828	Protein conserved in bacteria
CLSAP_RS17220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLSAP_RS17230	COG3051	citrate lyase alpha subunit
CLSAP_RS17245	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CLSAP_RS17250	COG1802	Transcriptional regulator
CLSAP_RS17260	COG0840	transmembrane signaling receptor activity
CLSAP_RS17265	COG0583	DNA-binding transcription factor activity
CLSAP_RS17275	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS17280	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS17290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS17295	COG2207	Transcriptional regulator
CLSAP_RS17320	COG5002	protein histidine kinase activity
CLSAP_RS17325	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS17335	COG0348	domain, Protein
CLSAP_RS17360	COG1937	Protein conserved in bacteria
CLSAP_RS17370	COG0791	NLP P60 protein
CLSAP_RS17375	COG2884	Cell division ATP-binding protein ftsE
CLSAP_RS17380	COG2177	Part of the ABC transporter FtsEX involved in
CLSAP_RS17395	COG3158	transport of potassium into the cell
CLSAP_RS17400	COG5002	protein histidine kinase activity
CLSAP_RS17405	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS17435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLSAP_RS17470	COG0778	Nitroreductase
CLSAP_RS17485	COG0772	Belongs to the SEDS family
CLSAP_RS17495	COG0583	DNA-binding transcription factor activity
CLSAP_RS17500	COG0242	peptide deformylase activity
CLSAP_RS17540	COG1733	regulation of RNA biosynthetic process
CLSAP_RS17555	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CLSAP_RS17570	COG1263	PTS System
CLSAP_RS17570	COG2190	(PTS) system
CLSAP_RS17570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS17575	COG0583	DNA-binding transcription factor activity
CLSAP_RS17590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLSAP_RS17600	COG1027	Aspartate ammonia-lyase
CLSAP_RS17615	COG1454	alcohol dehydrogenase
CLSAP_RS17620	COG0235	Class ii aldolase
CLSAP_RS17625	COG4806	L-rhamnose isomerase
CLSAP_RS17630	COG1070	Carbohydrate kinase
CLSAP_RS17645	COG0697	spore germination
CLSAP_RS17660	COG0004	ammonium transporteR
CLSAP_RS17665	COG0347	Belongs to the P(II) protein family
CLSAP_RS17670	COG1403	HNH endonuclease
CLSAP_RS17680	COG4670	ketone body catabolic process
CLSAP_RS17695	COG0826	peptidase U32
CLSAP_RS17700	COG1114	Component of the transport system for branched-chain amino acids
CLSAP_RS17705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLSAP_RS17760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLSAP_RS17765	COG4988	ABC transporter
CLSAP_RS17770	COG1294	oxidase, subunit
CLSAP_RS17775	COG1271	oxidase subunit
CLSAP_RS17790	COG0840	transmembrane signaling receptor activity
CLSAP_RS17805	COG0493	'glutamate synthase
CLSAP_RS17805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLSAP_RS17810	COG1053	succinate dehydrogenase
CLSAP_RS17815	COG0583	DNA-binding transcription factor activity
CLSAP_RS17835	COG0561	phosphatase activity
CLSAP_RS17845	COG0840	transmembrane signaling receptor activity
CLSAP_RS17855	COG0658	competence protein
CLSAP_RS17855	COG2333	competence protein COMEC
CLSAP_RS17860	COG1854	S-ribosylhomocysteine lyase activity
CLSAP_RS17870	COG2826	transposase and inactivated derivatives, IS30 family
CLSAP_RS17875	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLSAP_RS17885	COG2703	oxygen carrier activity
CLSAP_RS17900	COG2201	protein-glutamate methylesterase activity
CLSAP_RS17910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS17915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS17925	COG0765	amino acid transport
CLSAP_RS17930	COG0765	amino acid transport
CLSAP_RS17935	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLSAP_RS17940	COG0833	amino acid
CLSAP_RS17945	COG0004	ammonium transporteR
CLSAP_RS17965	COG0534	Mate efflux family protein
CLSAP_RS17970	COG0328	RNA-DNA hybrid ribonuclease activity
CLSAP_RS17990	COG0861	Integral membrane protein TerC family
CLSAP_RS17995	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS17995	COG2199	diguanylate cyclase activity
CLSAP_RS18050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLSAP_RS18100	COG2814	Major facilitator Superfamily
CLSAP_RS18115	COG1132	(ABC) transporter
CLSAP_RS18125	COG0583	DNA-binding transcription factor activity
CLSAP_RS18130	COG0840	transmembrane signaling receptor activity
CLSAP_RS18150	COG1846	Transcriptional regulator
CLSAP_RS18175	COG3022	response to hydroperoxide
CLSAP_RS18180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLSAP_RS18190	COG4191	Histidine kinase
CLSAP_RS18195	COG2204	response regulator
CLSAP_RS18225	COG4521	taurine ABC transporter
CLSAP_RS18230	COG0450	alkyl hydroperoxide reductase
CLSAP_RS18235	COG3634	alkyl hydroperoxide reductase activity
CLSAP_RS18240	COG2207	Transcriptional regulator
CLSAP_RS18240	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS18350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLSAP_RS18350	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CLSAP_RS18355	COG0583	DNA-binding transcription factor activity
CLSAP_RS18360	COG0778	Nitroreductase
CLSAP_RS18375	COG1187	pseudouridine synthase activity
CLSAP_RS18380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLSAP_RS18390	COG0488	(ABC) transporter
CLSAP_RS18410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLSAP_RS18430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS18430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS18435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS18440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS18440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLSAP_RS18440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS18445	COG0840	transmembrane signaling receptor activity
CLSAP_RS18450	COG1902	pentaerythritol trinitrate reductase activity
CLSAP_RS18455	COG1396	sequence-specific DNA binding
CLSAP_RS18460	COG0697	spore germination
CLSAP_RS18470	COG1984	allophanate hydrolase subunit 2
CLSAP_RS18475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLSAP_RS18480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLSAP_RS18485	COG4336	lyase activity
CLSAP_RS18500	COG1522	sequence-specific DNA binding
CLSAP_RS18530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLSAP_RS18535	COG2226	methyltransferase
CLSAP_RS18545	COG3973	AAA domain
CLSAP_RS18555	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS18615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLSAP_RS18635	COG0322	excinuclease ABC activity
CLSAP_RS18690	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLSAP_RS18710	COG3586	endonuclease activity
CLSAP_RS18745	COG0693	protein deglycase activity
CLSAP_RS18770	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CLSAP_RS18775	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLSAP_RS18780	COG0309	Hydrogenase expression formation protein (HypE)
CLSAP_RS18785	COG0409	Hydrogenase expression formation protein
CLSAP_RS18790	COG0298	carbon dioxide binding
CLSAP_RS18795	COG0805	protein transport
CLSAP_RS18800	COG0805	protein transport
CLSAP_RS18805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLSAP_RS18810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLSAP_RS18815	COG0375	protein maturation
CLSAP_RS18820	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLSAP_RS18845	COG0457	Tetratricopeptide repeat
CLSAP_RS18845	COG0705	Rhomboid family
CLSAP_RS18850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLSAP_RS18855	COG5001	Diguanylate cyclase
CLSAP_RS18855	COG3300	MHYT domain
CLSAP_RS18880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLSAP_RS18885	COG3875	lactate racemase activity
CLSAP_RS18900	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS18900	COG2207	Transcriptional regulator
CLSAP_RS18955	COG1690	Belongs to the RtcB family
CLSAP_RS18990	COG1714	RDD family
CLSAP_RS18995	COG0616	signal peptide processing
CLSAP_RS19010	COG1174	glycine betaine transport
CLSAP_RS19030	COG0167	dihydroorotate dehydrogenase activity
CLSAP_RS19030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLSAP_RS19040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLSAP_RS19045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLSAP_RS19050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLSAP_RS19055	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLSAP_RS19065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLSAP_RS19075	COG1960	acyl-CoA dehydrogenase activity
CLSAP_RS19080	COG0277	FAD linked oxidase domain protein
CLSAP_RS19085	COG1620	l-lactate permease
CLSAP_RS19090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CLSAP_RS19095	COG2086	electron transfer activity
CLSAP_RS19105	COG0789	Transcriptional regulator
CLSAP_RS19105	COG4978	Transcriptional regulator
CLSAP_RS19110	COG5001	Diguanylate cyclase
CLSAP_RS19115	COG0025	NhaP-type Na H and K H
CLSAP_RS19150	COG1307	EDD domain protein, DegV family
CLSAP_RS19160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLSAP_RS19180	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLSAP_RS19195	COG2272	Belongs to the type-B carboxylesterase lipase family
CLSAP_RS19205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLSAP_RS19210	COG0248	Ppx GppA phosphatase
CLSAP_RS19215	COG0628	permease
CLSAP_RS19225	COG0534	Mate efflux family protein
CLSAP_RS19230	COG0840	transmembrane signaling receptor activity
CLSAP_RS19240	COG4632	Exopolysaccharide biosynthesis protein
CLSAP_RS19240	COG5434	Belongs to the glycosyl hydrolase 28 family
CLSAP_RS19260	COG2137	regulation of response to DNA damage stimulus
CLSAP_RS19265	COG0612	Peptidase, M16
CLSAP_RS19270	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS19275	COG5002	protein histidine kinase activity
CLSAP_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS19290	COG0252	asparaginase activity
CLSAP_RS19295	COG1126	abc transporter atp-binding protein
CLSAP_RS19300	COG0765	amino acid transport
CLSAP_RS19305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS19310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS19420	COG4106	trans-aconitate 2-methyltransferase activity
CLSAP_RS19435	COG0494	nUDIX hydrolase
CLSAP_RS19440	COG0561	phosphatase activity
CLSAP_RS19450	COG3940	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS19460	COG3507	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS19465	COG3534	alpha-L-arabinofuranosidase
CLSAP_RS19470	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS19475	COG1175	transmembrane transport
CLSAP_RS19480	COG1653	transport
CLSAP_RS19490	COG0708	Exodeoxyribonuclease III
CLSAP_RS19505	COG2848	UPF0210 protein
CLSAP_RS19515	COG0726	polysaccharide deacetylase
CLSAP_RS19530	COG1522	sequence-specific DNA binding
CLSAP_RS19535	COG1027	Aspartate ammonia-lyase
CLSAP_RS19565	COG0840	transmembrane signaling receptor activity
CLSAP_RS19575	COG2252	PERMEase
CLSAP_RS19580	COG0584	glycerophosphoryl diester phosphodiesterase
CLSAP_RS19585	COG1653	transport
CLSAP_RS19590	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS19595	COG1175	transmembrane transport
CLSAP_RS19600	COG3842	ATPase activity
CLSAP_RS19610	COG3118	belongs to the thioredoxin family
CLSAP_RS19615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLSAP_RS19625	COG0730	response to heat
CLSAP_RS19655	COG4632	Exopolysaccharide biosynthesis protein
CLSAP_RS19655	COG5434	Belongs to the glycosyl hydrolase 28 family
CLSAP_RS19670	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CLSAP_RS19685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CLSAP_RS19690	COG0588	phosphoglycerate mutase activity
CLSAP_RS19700	COG1309	transcriptional regulator
CLSAP_RS19710	COG0310	cobalt ion transport
CLSAP_RS19715	COG1122	ATPase activity
CLSAP_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS19740	COG0789	Transcriptional regulator
CLSAP_RS19745	COG1592	Rubrerythrin
CLSAP_RS19745	COG1773	rubredoxin
CLSAP_RS19750	COG4677	pectinesterase activity
CLSAP_RS19755	COG0778	Nitroreductase
CLSAP_RS19765	COG1741	Belongs to the pirin family
CLSAP_RS19770	COG1733	regulation of RNA biosynthetic process
CLSAP_RS19775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLSAP_RS19790	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS19795	COG2190	(PTS) system
CLSAP_RS19795	COG1263	PTS System
CLSAP_RS19795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS19815	COG1472	Belongs to the glycosyl hydrolase 3 family
CLSAP_RS19825	COG2207	Transcriptional regulator
CLSAP_RS19830	COG1803	Methylglyoxal synthase
CLSAP_RS19835	COG0840	transmembrane signaling receptor activity
CLSAP_RS19870	COG2273	Hydrolase Family 16
CLSAP_RS19875	COG4753	response regulator
CLSAP_RS19875	COG2207	Transcriptional regulator
CLSAP_RS19880	COG2972	Histidine kinase
CLSAP_RS19890	COG0840	transmembrane signaling receptor activity
CLSAP_RS19895	COG0693	protein deglycase activity
CLSAP_RS19905	COG0583	DNA-binding transcription factor activity
CLSAP_RS19930	COG1940	carbohydrate kinase activity
CLSAP_RS19935	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS19960	COG1472	Belongs to the glycosyl hydrolase 3 family
CLSAP_RS19965	COG2211	Major facilitator Superfamily
CLSAP_RS20005	COG2211	Major facilitator Superfamily
CLSAP_RS20010	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS20030	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS20045	COG2271	Major facilitator Superfamily
CLSAP_RS20060	COG2323	membrane
CLSAP_RS20070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLSAP_RS20085	COG1846	Transcriptional regulator
CLSAP_RS20090	COG2814	Major facilitator Superfamily
CLSAP_RS20095	COG1566	PFAM secretion protein HlyD family protein
CLSAP_RS20105	COG1846	Transcriptional regulator
CLSAP_RS20110	COG4106	trans-aconitate 2-methyltransferase activity
CLSAP_RS20120	COG5599	Phosphatase
CLSAP_RS20130	COG3958	Transketolase
CLSAP_RS20135	COG3959	Transketolase, thiamine diphosphate binding domain
CLSAP_RS20160	COG3037	sugar-specific permease SgaT UlaA
CLSAP_RS20175	COG1349	DNA-binding transcription factor activity
CLSAP_RS20180	COG0371	Dehydrogenase
CLSAP_RS20195	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS20205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS20215	COG0129	dihydroxy-acid dehydratase activity
CLSAP_RS20220	COG2186	Transcriptional regulator
CLSAP_RS20225	COG2814	Major facilitator Superfamily
CLSAP_RS20230	COG0531	amino acid
CLSAP_RS20240	COG5002	protein histidine kinase activity
CLSAP_RS20245	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS20260	COG1733	regulation of RNA biosynthetic process
CLSAP_RS20295	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS20295	COG2207	Transcriptional regulator
CLSAP_RS20310	COG3104	oligopeptide transport
CLSAP_RS20330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLSAP_RS20335	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS20340	COG1528	Iron-storage protein
CLSAP_RS20345	COG0583	DNA-binding transcription factor activity
CLSAP_RS20360	COG1914	H( )-stimulated, divalent metal cation uptake system
CLSAP_RS20370	COG0148	phosphopyruvate hydratase activity
CLSAP_RS20380	COG0484	heat shock protein binding
CLSAP_RS20405	COG0613	PHP domain protein
CLSAP_RS20410	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLSAP_RS20445	COG1234	tRNA 3'-trailer cleavage
CLSAP_RS20450	COG0538	isocitrate dehydrogenase activity
CLSAP_RS20455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CLSAP_RS20470	COG0163	prenyltransferase activity
CLSAP_RS20490	COG0583	DNA-binding transcription factor activity
CLSAP_RS20500	COG2851	Citrate transporter
CLSAP_RS20525	COG3051	citrate lyase alpha subunit
CLSAP_RS20535	COG3052	prosthetic group binding
CLSAP_RS20540	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CLSAP_RS20545	COG0281	malic enzyme
CLSAP_RS20550	COG3493	citrate carrier protein
CLSAP_RS20560	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLSAP_RS20565	COG3493	citrate carrier protein
CLSAP_RS20585	COG0493	'glutamate synthase
CLSAP_RS20590	COG0070	glutamate synthase
CLSAP_RS20590	COG0067	glutamate synthase
CLSAP_RS20590	COG0069	glutamate synthase activity
CLSAP_RS20605	COG0527	aspartate kinase activity
CLSAP_RS20620	COG1136	(ABC) transporter
CLSAP_RS20630	COG0586	Pfam SNARE associated Golgi protein
CLSAP_RS20655	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLSAP_RS20675	COG2165	general secretion pathway protein
CLSAP_RS20680	COG1459	type II secretion system
CLSAP_RS20685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLSAP_RS20690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLSAP_RS20730	COG3706	GGDEF domain
CLSAP_RS20735	COG1739	Uncharacterized protein family UPF0029
CLSAP_RS20740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS20755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLSAP_RS20770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLSAP_RS20785	COG1342	Belongs to the UPF0251 family
CLSAP_RS20795	COG0583	DNA-binding transcription factor activity
CLSAP_RS20805	COG0662	Cupin 2, conserved barrel domain protein
CLSAP_RS20810	COG1376	ErfK ybiS ycfS ynhG family protein
CLSAP_RS20815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLSAP_RS20820	COG2226	methyltransferase
CLSAP_RS20825	COG0105	UTP biosynthetic process
CLSAP_RS20830	COG1254	Belongs to the acylphosphatase family
CLSAP_RS20835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLSAP_RS20840	COG0561	phosphatase activity
CLSAP_RS20850	COG1216	Glycosyl transferase, family 2
CLSAP_RS20855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLSAP_RS20870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLSAP_RS20880	COG4786	Flagellar basal body rod
CLSAP_RS20885	COG4786	Flagellar basal body rod
CLSAP_RS20895	COG1191	sigma factor activity
CLSAP_RS20905	COG0455	bacterial-type flagellum organization
CLSAP_RS20910	COG1419	protein localization to endoplasmic reticulum
CLSAP_RS20915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLSAP_RS20920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLSAP_RS20930	COG1338	Plays a role in the flagellum-specific transport system
CLSAP_RS20945	COG1582	Flagellar protein (FlbD)
CLSAP_RS20950	COG4786	Flagellar basal body rod
CLSAP_RS20975	COG1157	protein secretion by the type III secretion system
CLSAP_RS20985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLSAP_RS20995	COG1677	Flagellar hook-basal body complex protein FliE
CLSAP_RS21005	COG1815	bacterial-type flagellum-dependent cell motility
CLSAP_RS21010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLSAP_RS21055	COG2089	acid synthase
CLSAP_RS21060	COG0562	UDP-galactopyranose mutase
CLSAP_RS21080	COG1216	Glycosyl transferase, family 2
CLSAP_RS21085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLSAP_RS21095	COG2089	acid synthase
CLSAP_RS21105	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CLSAP_RS21115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLSAP_RS21125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLSAP_RS21130	COG0110	maltose O-acetyltransferase activity
CLSAP_RS21150	COG1215	transferase activity, transferring glycosyl groups
CLSAP_RS21165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLSAP_RS21195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLSAP_RS21215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLSAP_RS21225	COG2226	methyltransferase
CLSAP_RS21230	COG1213	nucleotidyl transferase
CLSAP_RS21240	COG0574	Belongs to the PEP-utilizing enzyme family
CLSAP_RS21240	COG3848	Pyruvate phosphate dikinase
CLSAP_RS21245	COG0529	Catalyzes the synthesis of activated sulfate
CLSAP_RS21255	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CLSAP_RS21260	COG1011	Hydrolase
CLSAP_RS21270	COG1086	Polysaccharide biosynthesis protein
CLSAP_RS21285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLSAP_RS21295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLSAP_RS21300	COG1516	flagellar protein fliS
CLSAP_RS21315	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLSAP_RS21320	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CLSAP_RS21330	COG1256	bacterial-type flagellum assembly
CLSAP_RS21330	COG4786	Flagellar basal body rod
CLSAP_RS21345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLSAP_RS21345	COG1776	CheC inhibitor of MCP methylation
CLSAP_RS21350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLSAP_RS21355	COG0835	chemotaxis
CLSAP_RS21360	COG2201	protein-glutamate methylesterase activity
CLSAP_RS21365	COG1776	CheC inhibitor of MCP methylation
CLSAP_RS21370	COG2198	Histidine kinase
CLSAP_RS21370	COG0643	Histidine kinase
CLSAP_RS21375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLSAP_RS21380	COG2201	protein-glutamate methylesterase activity
CLSAP_RS21410	COG0436	Aminotransferase
CLSAP_RS21425	COG0655	NAD(P)H dehydrogenase (quinone) activity
CLSAP_RS21430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLSAP_RS21435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLSAP_RS21435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CLSAP_RS21440	COG0693	protein deglycase activity
CLSAP_RS21445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLSAP_RS21450	COG0187	DNA topoisomerase II activity
CLSAP_RS21455	COG1215	transferase activity, transferring glycosyl groups
CLSAP_RS21460	COG0705	Rhomboid family
CLSAP_RS21460	COG0457	Tetratricopeptide repeat
CLSAP_RS21465	COG1164	Oligoendopeptidase f
CLSAP_RS21475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLSAP_RS21480	COG1696	Membrane protein involved in D-alanine export
CLSAP_RS21490	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CLSAP_RS21495	COG1121	(ABC) transporter
CLSAP_RS21500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLSAP_RS21505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLSAP_RS21505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLSAP_RS21510	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CLSAP_RS21510	COG0028	Belongs to the TPP enzyme family
CLSAP_RS21520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLSAP_RS21545	COG1131	(ABC) transporter
CLSAP_RS21550	COG1725	Transcriptional regulator
CLSAP_RS21570	COG0840	transmembrane signaling receptor activity
CLSAP_RS21575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLSAP_RS21580	COG2508	Transcriptional regulator
CLSAP_RS21585	COG2508	Transcriptional regulator
CLSAP_RS21590	COG0765	amino acid transport
CLSAP_RS21595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS21600	COG1126	abc transporter atp-binding protein
CLSAP_RS21625	COG2703	oxygen carrier activity
CLSAP_RS21630	COG1533	DNA photolyase activity
CLSAP_RS21650	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CLSAP_RS21655	COG1982	Orn Lys Arg decarboxylase major
CLSAP_RS21660	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CLSAP_RS21680	COG0840	transmembrane signaling receptor activity
CLSAP_RS21690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLSAP_RS21695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLSAP_RS21700	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CLSAP_RS21710	COG0840	transmembrane signaling receptor activity
CLSAP_RS21710	COG5278	phosphoserine phosphatase activity
CLSAP_RS21725	COG0288	reversible hydration of carbon dioxide
CLSAP_RS21740	COG2972	Histidine kinase
CLSAP_RS21745	COG4753	response regulator
CLSAP_RS21745	COG2207	Transcriptional regulator
CLSAP_RS21745	COG4753	response regulator
CLSAP_RS21745	COG2207	Transcriptional regulator
CLSAP_RS21750	COG4211	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS21760	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS21780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLSAP_RS21795	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS21800	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS21805	COG3845	ABC transporter
CLSAP_RS21810	COG1744	ABC transporter substrate-binding protein PnrA-like
CLSAP_RS21815	COG0813	purine-nucleoside phosphorylase activity
CLSAP_RS21825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLSAP_RS21830	COG0295	cytidine deaminase activity
CLSAP_RS21835	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CLSAP_RS21840	COG2188	Transcriptional regulator
CLSAP_RS21850	COG4214	carbohydrate transport
CLSAP_RS21855	COG1129	ABC transporter
CLSAP_RS21860	COG4213	ABC transporter substrate-binding protein
CLSAP_RS21890	COG2160	L-arabinose isomerase activity
CLSAP_RS21895	COG2972	Histidine kinase
CLSAP_RS21900	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS21905	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLSAP_RS21910	COG1129	ABC transporter
CLSAP_RS21915	COG1879	ABC-type sugar transport system periplasmic component
CLSAP_RS21925	COG2197	response regulator
CLSAP_RS21935	COG0561	phosphatase activity
CLSAP_RS21940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS21955	COG0835	chemotaxis
CLSAP_RS21955	COG0784	Response regulator, receiver
CLSAP_RS21960	COG3853	Toxic anion resistance protein (TelA)
CLSAP_RS21970	COG3546	catalase activity
CLSAP_RS21975	COG0840	transmembrane signaling receptor activity
CLSAP_RS21975	COG5278	phosphoserine phosphatase activity
CLSAP_RS22020	COG1131	(ABC) transporter
CLSAP_RS22030	COG0018	arginyl-trna synthetase
CLSAP_RS22040	COG1395	domain, Protein
CLSAP_RS22045	COG3711	transcriptional antiterminator
CLSAP_RS22050	COG1263	PTS System
CLSAP_RS22050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS22050	COG2190	(PTS) system
CLSAP_RS22060	COG1522	sequence-specific DNA binding
CLSAP_RS22065	COG1522	sequence-specific DNA binding
CLSAP_RS22070	COG0535	radical SAM domain protein
CLSAP_RS22075	COG0535	radical SAM domain protein
CLSAP_RS22100	COG4585	Histidine kinase
CLSAP_RS22105	COG2197	response regulator
CLSAP_RS22125	COG1882	Formate acetyltransferase
CLSAP_RS22130	COG1349	DNA-binding transcription factor activity
CLSAP_RS22140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLSAP_RS22155	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS22165	COG1053	succinate dehydrogenase
CLSAP_RS22205	COG0493	'glutamate synthase
CLSAP_RS22210	COG1609	Transcriptional regulator
CLSAP_RS22215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLSAP_RS22220	COG1070	Carbohydrate kinase
CLSAP_RS22240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS22240	COG3711	transcriptional antiterminator
CLSAP_RS22255	COG2211	Major facilitator Superfamily
CLSAP_RS22265	COG2814	Major facilitator Superfamily
CLSAP_RS22280	COG1695	Transcriptional regulator
CLSAP_RS22285	COG0561	phosphatase activity
CLSAP_RS22290	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS22325	COG0840	transmembrane signaling receptor activity
CLSAP_RS22330	COG2508	Transcriptional regulator
CLSAP_RS22335	COG1113	amino acid transport
CLSAP_RS22350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLSAP_RS22355	COG4708	membrane
CLSAP_RS22360	COG0737	Belongs to the 5'-nucleotidase family
CLSAP_RS22380	COG1120	ATPase activity
CLSAP_RS22385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLSAP_RS22390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLSAP_RS22400	COG2116	formate transmembrane transporter activity
CLSAP_RS22410	COG2207	Transcriptional regulator
CLSAP_RS22410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLSAP_RS22415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLSAP_RS22420	COG1120	ATPase activity
CLSAP_RS22440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLSAP_RS22445	COG0583	DNA-binding transcription factor activity
CLSAP_RS22450	COG2205	protein histidine kinase activity
CLSAP_RS22470	COG1131	(ABC) transporter
CLSAP_RS22480	COG1136	(ABC) transporter
CLSAP_RS22490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLSAP_RS22495	COG0363	glucosamine-6-phosphate deaminase activity
CLSAP_RS22510	COG1309	transcriptional regulator
CLSAP_RS22515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLSAP_RS22525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS22540	COG1609	Transcriptional regulator
CLSAP_RS22555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLSAP_RS22560	COG3958	Transketolase
CLSAP_RS22565	COG3959	Transketolase, thiamine diphosphate binding domain
CLSAP_RS22580	COG1312	Catalyzes the dehydration of D-mannonate
CLSAP_RS22590	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS22595	COG1175	transmembrane transport
CLSAP_RS22605	COG0840	transmembrane signaling receptor activity
CLSAP_RS22615	COG2207	Transcriptional regulator
CLSAP_RS22615	COG4753	response regulator
CLSAP_RS22620	COG2972	Histidine kinase
CLSAP_RS22630	COG2190	(PTS) system
CLSAP_RS22630	COG1263	PTS System
CLSAP_RS22630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS22635	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS22635	COG4977	sequence-specific DNA binding
CLSAP_RS22650	COG3534	alpha-L-arabinofuranosidase
CLSAP_RS22655	COG4753	response regulator
CLSAP_RS22655	COG2207	Transcriptional regulator
CLSAP_RS22660	COG2972	Histidine kinase
CLSAP_RS22675	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLSAP_RS22680	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS22685	COG4209	transmembrane transport
CLSAP_RS22710	COG3940	Belongs to the glycosyl hydrolase 43 family
CLSAP_RS22720	COG1132	(ABC) transporter
CLSAP_RS22725	COG1132	(ABC) transporter
CLSAP_RS22735	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS22740	COG1175	transmembrane transport
CLSAP_RS22745	COG1653	transport
CLSAP_RS22750	COG2207	Transcriptional regulator
CLSAP_RS22755	COG2972	Histidine kinase
CLSAP_RS22765	COG1472	Belongs to the glycosyl hydrolase 3 family
CLSAP_RS22800	COG3716	PTS system mannose fructose sorbose family IID component
CLSAP_RS22805	COG3715	PTS system
CLSAP_RS22835	COG1904	glucuronate isomerase
CLSAP_RS22840	COG0246	Mannitol dehydrogenase
CLSAP_RS22845	COG1312	Catalyzes the dehydration of D-mannonate
CLSAP_RS22850	COG1802	Transcriptional regulator
CLSAP_RS22860	COG0318	PFAM AMP-dependent synthetase and ligase
CLSAP_RS22870	COG0840	transmembrane signaling receptor activity
CLSAP_RS22880	COG5002	protein histidine kinase activity
CLSAP_RS22900	COG0352	thiamine-phosphate diphosphorylase activity
CLSAP_RS22910	COG2022	thiamine diphosphate biosynthetic process
CLSAP_RS22915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLSAP_RS22925	COG0531	amino acid
CLSAP_RS22940	COG0251	oxidation-reduction process
CLSAP_RS22945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLSAP_RS22975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS22980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS22985	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS22990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS22990	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS23025	COG2508	Transcriptional regulator
CLSAP_RS23025	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CLSAP_RS23035	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CLSAP_RS23040	COG5002	protein histidine kinase activity
CLSAP_RS23040	COG0784	Response regulator, receiver
CLSAP_RS23040	COG2205	protein histidine kinase activity
CLSAP_RS23045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLSAP_RS23065	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS23070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS23070	COG2190	(PTS) system
CLSAP_RS23070	COG1263	PTS System
CLSAP_RS23075	COG3711	transcriptional antiterminator
CLSAP_RS23080	COG2706	6-phosphogluconolactonase activity
CLSAP_RS23095	COG2732	(Barnase) inhibitor
CLSAP_RS23100	COG4290	ribonuclease
CLSAP_RS23110	COG1733	regulation of RNA biosynthetic process
CLSAP_RS23115	COG0667	Aldo Keto reductase
CLSAP_RS23120	COG2814	Major facilitator Superfamily
CLSAP_RS23135	COG1904	glucuronate isomerase
CLSAP_RS23140	COG0246	Mannitol dehydrogenase
CLSAP_RS23145	COG1312	Catalyzes the dehydration of D-mannonate
CLSAP_RS23150	COG1802	Transcriptional regulator
CLSAP_RS23170	COG2814	Major facilitator Superfamily
CLSAP_RS23175	COG0778	Nitroreductase
CLSAP_RS23185	COG0583	DNA-binding transcription factor activity
CLSAP_RS23195	COG0702	epimerase
CLSAP_RS23200	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS23205	COG1263	PTS System
CLSAP_RS23205	COG2190	(PTS) system
CLSAP_RS23205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS23225	COG1486	melibiose metabolic process
CLSAP_RS23230	COG1263	PTS System
CLSAP_RS23230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS23235	COG1737	Transcriptional regulator
CLSAP_RS23245	COG0789	Transcriptional regulator
CLSAP_RS23265	COG3976	FMN-binding domain protein
CLSAP_RS23265	COG0431	NADPH-dependent FMN reductase
CLSAP_RS23265	COG1053	succinate dehydrogenase
CLSAP_RS23280	COG5002	protein histidine kinase activity
CLSAP_RS23290	COG1876	peptidase activity
CLSAP_RS23300	COG5002	protein histidine kinase activity
CLSAP_RS23315	COG1073	alpha beta
CLSAP_RS23335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLSAP_RS23340	COG0366	Alpha amylase catalytic
CLSAP_RS23345	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS23355	COG1653	transport
CLSAP_RS23370	COG1028	Short-chain dehydrogenase reductase Sdr
CLSAP_RS23385	COG0789	Transcriptional regulator
CLSAP_RS23395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLSAP_RS23405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLSAP_RS23415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLSAP_RS23420	COG3964	amidohydrolase
CLSAP_RS23425	COG0471	metal ion transport
CLSAP_RS23435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLSAP_RS23440	COG1131	(ABC) transporter
CLSAP_RS23445	COG1349	DNA-binding transcription factor activity
CLSAP_RS23450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLSAP_RS23455	COG2271	Major facilitator Superfamily
CLSAP_RS23460	COG0800	Aldolase
CLSAP_RS23465	COG1414	Transcriptional regulator
CLSAP_RS23475	COG0842	Transport permease protein
CLSAP_RS23475	COG1129	ABC transporter
CLSAP_RS23480	COG3620	sequence-specific DNA binding
CLSAP_RS23485	COG1733	regulation of RNA biosynthetic process
CLSAP_RS23505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLSAP_RS23510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLSAP_RS23525	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS23525	COG2207	Transcriptional regulator
CLSAP_RS23530	COG2207	Transcriptional regulator
CLSAP_RS23530	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS23535	COG4670	ketone body catabolic process
CLSAP_RS23540	COG2030	dehydratase
CLSAP_RS23570	COG4565	transcriptional regulatory protein
CLSAP_RS23575	COG3290	protein histidine kinase activity
CLSAP_RS23585	COG0281	malic enzyme
CLSAP_RS23590	COG1404	Belongs to the peptidase S8 family
CLSAP_RS23610	COG0641	radical SAM
CLSAP_RS23615	COG1132	(ABC) transporter
CLSAP_RS23630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLSAP_RS23655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLSAP_RS23660	COG4978	Transcriptional regulator
CLSAP_RS23660	COG0789	Transcriptional regulator
CLSAP_RS23685	COG4978	Transcriptional regulator
CLSAP_RS23685	COG0789	Transcriptional regulator
CLSAP_RS23705	COG2770	Histidine kinase
CLSAP_RS23705	COG2208	phosphoserine phosphatase activity
CLSAP_RS23715	COG0840	transmembrane signaling receptor activity
CLSAP_RS23725	COG2364	Membrane
CLSAP_RS23730	COG0493	'glutamate synthase
CLSAP_RS23730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLSAP_RS23750	COG0756	dUTP diphosphatase activity
CLSAP_RS23760	COG3706	GGDEF domain
CLSAP_RS23765	COG0726	polysaccharide deacetylase
CLSAP_RS23785	COG0037	tRNA processing
CLSAP_RS23795	COG3191	aminopeptidase activity
CLSAP_RS23800	COG1131	(ABC) transporter
CLSAP_RS23810	COG1309	transcriptional regulator
CLSAP_RS23820	COG0542	response to heat
CLSAP_RS23825	COG0516	GMP reductase activity
CLSAP_RS23825	COG0517	IMP dehydrogenase activity
CLSAP_RS23850	COG1464	Belongs to the NlpA lipoprotein family
CLSAP_RS23855	COG2011	ABC-type metal ion transport system permease component
CLSAP_RS23860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLSAP_RS23865	COG0737	Belongs to the 5'-nucleotidase family
CLSAP_RS23870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLSAP_RS23875	COG0557	exoribonuclease II activity
CLSAP_RS23900	COG0148	phosphopyruvate hydratase activity
CLSAP_RS23910	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLSAP_RS23915	COG0149	triose-phosphate isomerase activity
CLSAP_RS23920	COG0126	phosphoglycerate kinase activity
CLSAP_RS23925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLSAP_RS23930	COG2390	Transcriptional regulator
CLSAP_RS23935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLSAP_RS23945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLSAP_RS23950	COG2720	vancomycin resistance protein
CLSAP_RS23965	COG0488	(ABC) transporter
CLSAP_RS23970	COG1309	transcriptional regulator
CLSAP_RS23980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLSAP_RS23990	COG1971	Probably functions as a manganese efflux pump
CLSAP_RS24000	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLSAP_RS24005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLSAP_RS24015	COG1045	serine acetyltransferase
CLSAP_RS24020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLSAP_RS24035	COG1597	lipid kinase activity
CLSAP_RS24040	COG1183	phosphatidylcholine synthase activity
CLSAP_RS24050	COG2719	SpoVR family
CLSAP_RS24055	COG2718	Belongs to the UPF0229 family
CLSAP_RS24060	COG2766	serine protein kinase
CLSAP_RS24065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLSAP_RS24075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLSAP_RS24080	COG1309	transcriptional regulator
CLSAP_RS24090	COG1132	(ABC) transporter
CLSAP_RS24095	COG1566	PFAM secretion protein HlyD family protein
CLSAP_RS24100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLSAP_RS24105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLSAP_RS24110	COG0840	transmembrane signaling receptor activity
CLSAP_RS24125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLSAP_RS24130	COG2388	GCN5-related N-acetyl-transferase
CLSAP_RS24165	COG3833	ABC-type maltose transport systems, permease component
CLSAP_RS24180	COG1874	Beta-galactosidase
CLSAP_RS24180	COG0366	Alpha amylase catalytic
CLSAP_RS24185	COG2182	Extracellular solute-binding protein
CLSAP_RS24190	COG1609	Transcriptional regulator
CLSAP_RS24200	COG1064	alcohol dehydrogenase
CLSAP_RS24235	COG1555	photosystem II stabilization
CLSAP_RS24235	COG1596	polysaccharide export
CLSAP_RS24240	COG1686	Belongs to the peptidase S11 family
CLSAP_RS24250	COG0583	DNA-binding transcription factor activity
CLSAP_RS24255	COG5002	protein histidine kinase activity
CLSAP_RS24260	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS24265	COG0564	pseudouridine synthase activity
CLSAP_RS24270	COG1316	TRANSCRIPTIONal
CLSAP_RS24275	COG1713	HD superfamily hydrolase involved in NAD metabolism
CLSAP_RS24280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLSAP_RS24285	COG1534	Rna-binding protein
CLSAP_RS24290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLSAP_RS24295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLSAP_RS24315	COG1530	ribonuclease E activity
CLSAP_RS24335	COG4399	Belongs to the UPF0754 family
CLSAP_RS24340	COG3708	Transcriptional regulator
CLSAP_RS24340	COG2207	Transcriptional regulator
CLSAP_RS24370	COG3118	belongs to the thioredoxin family
CLSAP_RS24385	COG1164	Oligoendopeptidase f
CLSAP_RS24390	COG1501	Belongs to the glycosyl hydrolase 31 family
CLSAP_RS24395	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS24400	COG1175	transmembrane transport
CLSAP_RS24410	COG3275	phosphorelay sensor kinase activity
CLSAP_RS24415	COG4753	response regulator
CLSAP_RS24415	COG2207	Transcriptional regulator
CLSAP_RS24465	COG0772	Belongs to the SEDS family
CLSAP_RS24470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLSAP_RS24475	COG2894	cell division
CLSAP_RS24485	COG1489	DNA binding
CLSAP_RS24500	COG1792	Involved in formation and maintenance of cell shape
CLSAP_RS24505	COG1077	Cell shape determining protein MreB Mrl
CLSAP_RS24510	COG2003	Belongs to the UPF0758 family
CLSAP_RS24515	COG0424	maF-like protein
CLSAP_RS24525	COG3103	Sh3 type 3 domain protein
CLSAP_RS24525	COG1388	LysM domain
CLSAP_RS24525	COG0791	NLP P60 protein
CLSAP_RS24530	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLSAP_RS24540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLSAP_RS24540	COG0539	negative regulation of cytoplasmic translation
CLSAP_RS24550	COG1842	Phage shock protein A
CLSAP_RS24570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLSAP_RS24580	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLSAP_RS24590	COG0420	3'-5' exonuclease activity
CLSAP_RS24635	COG2188	Transcriptional regulator
CLSAP_RS24650	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS24665	COG1482	cell wall glycoprotein biosynthetic process
CLSAP_RS24685	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS24685	COG2207	Transcriptional regulator
CLSAP_RS24700	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CLSAP_RS24705	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS24710	COG1175	transmembrane transport
CLSAP_RS24725	COG3842	ATPase activity
CLSAP_RS24755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLSAP_RS24760	COG2271	Major facilitator Superfamily
CLSAP_RS24765	COG2271	Major facilitator Superfamily
CLSAP_RS24785	COG0583	DNA-binding transcription factor activity
CLSAP_RS24795	COG0583	DNA-binding transcription factor activity
CLSAP_RS24800	COG0163	prenyltransferase activity
CLSAP_RS24805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLSAP_RS24820	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CLSAP_RS24835	COG0077	Prephenate dehydratase
CLSAP_RS24835	COG1605	Chorismate mutase
CLSAP_RS24840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLSAP_RS24845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLSAP_RS24850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLSAP_RS24855	COG2273	Hydrolase Family 16
CLSAP_RS24855	COG5297	Belongs to the glycosyl hydrolase family 6
CLSAP_RS24880	COG0495	leucyl-tRNA aminoacylation
CLSAP_RS24895	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS24900	COG2205	protein histidine kinase activity
CLSAP_RS24900	COG2770	Histidine kinase
CLSAP_RS24935	COG2357	RelA SpoT domain protein
CLSAP_RS24945	COG0840	transmembrane signaling receptor activity
CLSAP_RS24945	COG3290	protein histidine kinase activity
CLSAP_RS24955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLSAP_RS24965	COG3426	butyrate kinase activity
CLSAP_RS25005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLSAP_RS25010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLSAP_RS25015	COG1609	Transcriptional regulator
CLSAP_RS25025	COG2199	diguanylate cyclase activity
CLSAP_RS25025	COG2203	Gaf domain
CLSAP_RS25030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLSAP_RS25035	COG0673	inositol 2-dehydrogenase activity
CLSAP_RS25040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLSAP_RS25055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLSAP_RS25065	COG3955	Domain of unknown function (DUF1919)
CLSAP_RS25080	COG1442	glycosyl transferase family 8
CLSAP_RS25080	COG1216	Glycosyl transferase, family 2
CLSAP_RS25085	COG3475	LICD family
CLSAP_RS25090	COG1442	glycosyl transferase family 8
CLSAP_RS25090	COG1216	Glycosyl transferase, family 2
CLSAP_RS25115	COG0395	ABC-type sugar transport system, permease component
CLSAP_RS25120	COG1175	transmembrane transport
CLSAP_RS25130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS25140	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS25145	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS25145	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS25150	COG1737	Transcriptional regulator
CLSAP_RS25160	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS25170	COG1486	melibiose metabolic process
CLSAP_RS25180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLSAP_RS25190	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLSAP_RS25195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS25195	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS25215	COG0697	spore germination
CLSAP_RS25230	COG4750	Nucleotidyl transferase
CLSAP_RS25250	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLSAP_RS25260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLSAP_RS25280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS25280	COG2199	diguanylate cyclase activity
CLSAP_RS25285	COG0840	transmembrane signaling receptor activity
CLSAP_RS25360	COG0463	Glycosyl transferase, family 2
CLSAP_RS25420	COG2264	protein methyltransferase activity
CLSAP_RS25440	COG1091	dTDP-4-dehydrorhamnose reductase activity
CLSAP_RS25450	COG1088	dTDP-glucose 4,6-dehydratase activity
CLSAP_RS25535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLSAP_RS25550	COG3459	Glycosyltransferase 36 associated
CLSAP_RS25565	COG1362	aminopeptidase activity
CLSAP_RS25570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLSAP_RS25575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLSAP_RS25585	COG1126	abc transporter atp-binding protein
CLSAP_RS25590	COG0765	amino acid transport
CLSAP_RS25595	COG1473	amidohydrolase
CLSAP_RS25600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLSAP_RS25605	COG3973	AAA domain
CLSAP_RS25610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLSAP_RS25620	COG0681	Belongs to the peptidase S26 family
CLSAP_RS25625	COG0681	Belongs to the peptidase S26 family
CLSAP_RS25630	COG0019	diaminopimelate decarboxylase activity
CLSAP_RS25660	COG1937	Protein conserved in bacteria
CLSAP_RS25665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLSAP_RS25665	COG2199	diguanylate cyclase activity
CLSAP_RS25670	COG1473	amidohydrolase
CLSAP_RS25675	COG1266	CAAX protease self-immunity
CLSAP_RS25690	COG0840	transmembrane signaling receptor activity
CLSAP_RS25690	COG3290	protein histidine kinase activity
CLSAP_RS25700	COG2204	response regulator
CLSAP_RS25705	COG5002	protein histidine kinase activity
CLSAP_RS25705	COG0784	Response regulator, receiver
CLSAP_RS25715	COG0840	transmembrane signaling receptor activity
CLSAP_RS25720	COG0835	chemotaxis
CLSAP_RS25730	COG2197	response regulator
CLSAP_RS25735	COG2201	protein-glutamate methylesterase activity
CLSAP_RS25745	COG0840	transmembrane signaling receptor activity
CLSAP_RS25750	COG1360	Flagellar Motor Protein
CLSAP_RS25755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLSAP_RS25760	COG2323	membrane
CLSAP_RS25770	COG2723	6-phospho-beta-galactosidase activity
CLSAP_RS25775	COG1592	Rubrerythrin
CLSAP_RS25815	COG3320	Male sterility
CLSAP_RS25815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLSAP_RS25830	COG0469	pyruvate kinase activity
CLSAP_RS25850	COG1481	regulation of sporulation
CLSAP_RS25855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CLSAP_RS25860	COG1660	Displays ATPase and GTPase activities
CLSAP_RS25865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLSAP_RS25870	COG0322	excinuclease ABC activity
CLSAP_RS25875	COG0768	penicillin binding
CLSAP_RS25880	COG0772	Belongs to the SEDS family
CLSAP_RS25895	COG0556	nucleotide-excision repair
CLSAP_RS25905	COG0793	Belongs to the peptidase S41A family
CLSAP_RS25905	COG3409	Peptidoglycan-binding domain 1 protein
CLSAP_RS25910	COG2177	Part of the ABC transporter FtsEX involved in
CLSAP_RS25915	COG2884	Cell division ATP-binding protein ftsE
CLSAP_RS25920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLSAP_RS25925	COG3958	Transketolase
CLSAP_RS25930	COG3959	Transketolase, thiamine diphosphate binding domain
CLSAP_RS25935	COG2337	Toxic component of a toxin-antitoxin (TA) module
CLSAP_RS25950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLSAP_RS25950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLSAP_RS25955	COG0736	holo-[acyl-carrier-protein] synthase activity
CLSAP_RS25965	COG0629	single-stranded DNA binding
CLSAP_RS25970	COG1295	ribonuclease BN
CLSAP_RS25975	COG1696	Membrane protein involved in D-alanine export
CLSAP_RS26010	COG2002	toxin-antitoxin pair type II binding
CLSAP_RS26015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLSAP_RS26020	COG2264	protein methyltransferase activity
CLSAP_RS26035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLSAP_RS26040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLSAP_RS26045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLSAP_RS26080	COG1058	Belongs to the CinA family
CLSAP_RS26080	COG1546	Belongs to the CinA family
CLSAP_RS26085	COG1940	carbohydrate kinase activity
CLSAP_RS26095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLSAP_RS26105	COG1368	sulfuric ester hydrolase activity
CLSAP_RS26145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CLSAP_RS26190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLSAP_RS26195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLSAP_RS26205	COG0058	SHG alpha-glucan phosphorylase activity
CLSAP_RS26210	COG0297	glycogen (starch) synthase activity
CLSAP_RS26240	COG3716	PTS system mannose fructose sorbose family IID component
CLSAP_RS26245	COG3715	PTS system
CLSAP_RS26250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS26250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS26255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLSAP_RS26255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS26260	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CLSAP_RS26260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLSAP_RS26265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLSAP_RS26270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLSAP_RS26275	COG0840	transmembrane signaling receptor activity
CLSAP_RS26280	COG1653	transport
CLSAP_RS26300	COG1418	mRNA catabolic process
CLSAP_RS26305	COG0745	RESPONSE REGULATOR receiver
CLSAP_RS26310	COG5002	protein histidine kinase activity
CLSAP_RS26325	COG0778	Nitroreductase
CLSAP_RS26345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLSAP_RS26350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLSAP_RS26355	COG4166	transmembrane transport
CLSAP_RS26360	COG4608	Belongs to the ABC transporter superfamily
CLSAP_RS26365	COG0444	Belongs to the ABC transporter superfamily
CLSAP_RS26370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLSAP_RS26375	COG0601	transmembrane transport
CLSAP_RS26410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLSAP_RS26415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLSAP_RS26425	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLSAP_RS26440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLSAP_RS26455	COG2201	protein-glutamate methylesterase activity
CLSAP_RS26460	COG0628	permease
CLSAP_RS26465	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CLSAP_RS26470	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLSAP_RS26485	COG4974	Belongs to the 'phage' integrase family
CLSAP_RS26505	COG1737	Transcriptional regulator
CLSAP_RS26510	COG1263	PTS System
CLSAP_RS26510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS26515	COG1486	melibiose metabolic process
CLSAP_RS26520	COG2190	(PTS) system
CLSAP_RS26530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLSAP_RS26535	COG2186	Transcriptional regulator
CLSAP_RS26545	COG1346	cytolysis
CLSAP_RS26555	COG0590	tRNA wobble adenosine to inosine editing
CLSAP_RS26560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLSAP_RS26565	COG1621	beta-fructofuranosidase activity
CLSAP_RS26570	COG1609	Transcriptional regulator
CLSAP_RS26575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLSAP_RS26575	COG1263	PTS System
CLSAP_RS26585	COG1132	(ABC) transporter
CLSAP_RS26590	COG1132	(ABC) transporter
CLSAP_RS26600	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLSAP_RS26620	COG1193	negative regulation of DNA recombination
CLSAP_RS26625	COG0384	phenazine biosynthesis protein PhzF
CLSAP_RS26630	COG1733	regulation of RNA biosynthetic process
CLSAP_RS26645	COG0840	transmembrane signaling receptor activity
CLSAP_RS26655	COG1979	alcohol dehydrogenase
CLSAP_RS26680	COG2207	Transcriptional regulator
CLSAP_RS26680	COG1917	Cupin 2, conserved barrel domain protein
CLSAP_RS26685	COG0596	Alpha beta hydrolase
CLSAP_RS26710	COG4689	acetoacetate decarboxylase
CLSAP_RS26720	COG2433	Pfam Transposase IS66
CLSAP_RS26760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLSAP_RS26825	COG3299	homolog of phage Mu protein gp47
CLSAP_RS26990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLSAP_RS27050	COG0488	(ABC) transporter
CLSAP_RS27060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLSAP_RS27070	COG0513	Belongs to the DEAD box helicase family
CLSAP_RS27080	COG0617	tRNA 3'-terminal CCA addition
CLSAP_RS27085	COG0347	Belongs to the P(II) protein family
CLSAP_RS27090	COG0004	ammonium transporteR
CLSAP_RS27100	COG0659	secondary active sulfate transmembrane transporter activity
CLSAP_RS27105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLSAP_RS27125	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CLSAP_RS27130	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CLSAP_RS27140	COG0683	leucine binding
CLSAP_RS27165	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CLSAP_RS27205	COG2201	protein-glutamate methylesterase activity
CLSAP_RS27210	COG2972	Histidine kinase
CLSAP_RS27215	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLSAP_RS27250	COG0657	acetylesterase activity
CLSAP_RS27260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLSAP_RS27265	COG0366	Alpha amylase catalytic
CLSAP_RS27270	COG1609	Transcriptional regulator
CLSAP_RS27280	COG0277	FAD linked oxidase domain protein
CLSAP_RS27315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLSAP_RS27380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLSAP_RS27385	COG2814	Major facilitator Superfamily
CLSAP_RS27390	COG0840	transmembrane signaling receptor activity
CLSAP_RS27395	COG0653	protein targeting
CLSAP_RS27400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLSAP_RS27425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CLSAP_RS27430	COG1404	Belongs to the peptidase S8 family
CLSAP_RS27480	COG2081	HI0933 family
CLSAP_RS27495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLSAP_RS27500	COG0281	malic enzyme
CLSAP_RS27510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLSAP_RS27520	COG0305	Participates in initiation and elongation during chromosome replication
CLSAP_RS27525	COG0470	DNA polymerase III
CLSAP_RS27525	COG1067	ATP-dependent peptidase activity
CLSAP_RS27530	COG0359	binds to the 23S rRNA
CLSAP_RS27535	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CLSAP_RS27545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLSAP_RS27550	COG0629	single-stranded DNA binding
CLSAP_RS27555	COG0360	Binds together with S18 to 16S ribosomal RNA
CLSAP_RS27565	COG0668	transmembrane transport
CLSAP_RS27595	COG1475	DNA binding
CLSAP_RS27600	COG1192	Involved in chromosome partitioning
CLSAP_RS27605	COG1475	DNA binding
CLSAP_RS27610	COG0357	Ribosomal RNA small subunit methyltransferase G
CLSAP_RS27615	COG0445	tRNA wobble uridine modification
CLSAP_RS27620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLSAP_RS27625	COG1847	R3H domain protein
CLSAP_RS27635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CLSAP_RS27640	COG0594	ribonuclease P activity
CLSAP_RS27645	COG0230	Belongs to the bacterial ribosomal protein bL34 family