locus-tag	class	description
CP523_RS00035	COG3328	transposase activity
CP523_RS00040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP523_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
CP523_RS00055	COG1187	pseudouridine synthase activity
CP523_RS00060	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CP523_RS00065	COG1737	Transcriptional regulator
CP523_RS00070	COG2081	HI0933 family
CP523_RS00080	COG0539	negative regulation of cytoplasmic translation
CP523_RS00080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP523_RS00095	COG0658	competence protein
CP523_RS00095	COG2333	competence protein COMEC
CP523_RS00135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP523_RS00140	COG2226	methyltransferase
CP523_RS00145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CP523_RS00155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP523_RS00165	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CP523_RS00175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP523_RS00185	COG4974	Belongs to the 'phage' integrase family
CP523_RS00215	COG0488	(ABC) transporter
CP523_RS00220	COG4708	membrane
CP523_RS00230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CP523_RS00245	COG1349	DNA-binding transcription factor activity
CP523_RS00250	COG1882	Formate acetyltransferase
CP523_RS00255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP523_RS00275	COG2755	lipolytic protein G-D-S-L family
CP523_RS00275	COG0657	acetylesterase activity
CP523_RS00285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP523_RS00310	COG2814	Major facilitator Superfamily
CP523_RS00315	COG0436	Aminotransferase
CP523_RS00320	COG1522	sequence-specific DNA binding
CP523_RS00325	COG0861	Integral membrane protein TerC family
CP523_RS00365	COG1136	(ABC) transporter
CP523_RS00385	COG2966	Psort location CytoplasmicMembrane, score
CP523_RS00390	COG1982	Orn Lys Arg decarboxylase major
CP523_RS00410	COG0628	permease
CP523_RS00425	COG4208	sulfate ABC transporter
CP523_RS00430	COG1840	ABC-type Fe3 transport system, periplasmic component
CP523_RS00440	COG1368	sulfuric ester hydrolase activity
CP523_RS00450	COG0494	nUDIX hydrolase
CP523_RS00465	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP523_RS00470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP523_RS00475	COG1882	Formate acetyltransferase
CP523_RS00480	COG2207	Transcriptional regulator
CP523_RS00495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP523_RS00500	COG1404	Belongs to the peptidase S8 family
CP523_RS00520	COG0840	transmembrane signaling receptor activity
CP523_RS00555	COG1349	DNA-binding transcription factor activity
CP523_RS00560	COG1105	Belongs to the carbohydrate kinase PfkB family
CP523_RS00565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP523_RS00565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP523_RS00565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP523_RS00570	COG2205	protein histidine kinase activity
CP523_RS00570	COG0784	Response regulator, receiver
CP523_RS00585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP523_RS00590	COG2359	stage V sporulation protein S
CP523_RS00595	COG1418	mRNA catabolic process
CP523_RS00605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP523_RS00620	COG0740	serine-type endopeptidase activity
CP523_RS00625	COG0527	aspartate kinase activity
CP523_RS00635	COG0612	Peptidase, M16
CP523_RS00650	COG0196	riboflavin kinase activity
CP523_RS00660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CP523_RS00680	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CP523_RS00685	COG0195	Participates in both transcription termination and antitermination
CP523_RS00690	COG0779	Required for maturation of 30S ribosomal subunits
CP523_RS00700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP523_RS00715	COG0628	permease
CP523_RS00720	COG4589	Belongs to the CDS family
CP523_RS00745	COG0052	Belongs to the universal ribosomal protein uS2 family
CP523_RS00760	COG0758	DNA mediated transformation
CP523_RS00765	COG0606	chelatase, subunit chli
CP523_RS00775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP523_RS00780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CP523_RS00785	COG0335	large ribosomal subunit rRNA binding
CP523_RS00790	COG0336	Belongs to the RNA methyltransferase TrmD family
CP523_RS00810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CP523_RS00820	COG0552	protein localization to endoplasmic reticulum
CP523_RS00835	COG0571	ribonuclease III activity
CP523_RS00865	COG0280	phosphate acetyltransferase
CP523_RS00870	COG1323	Belongs to the UPF0348 family
CP523_RS00890	COG0742	ribosomal rna small subunit methyltransferase
CP523_RS00895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CP523_RS00900	COG1461	Dihydroxyacetone kinase
CP523_RS00905	COG1302	Protein conserved in bacteria
CP523_RS00910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP523_RS00915	COG1564	THIamine pyrophosphokinase
CP523_RS00920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP523_RS00935	COG0631	protein serine/threonine phosphatase activity
CP523_RS00945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP523_RS00945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CP523_RS00950	COG2738	Putative neutral zinc metallopeptidase
CP523_RS00965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CP523_RS00970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CP523_RS00990	COG1561	YicC-like family, N-terminal region
CP523_RS00995	COG2252	PERMEase
CP523_RS01010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CP523_RS01015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP523_RS01030	COG0704	Plays a role in the regulation of phosphate uptake
CP523_RS01035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP523_RS01040	COG0581	inorganic phosphate transmembrane transporter activity
CP523_RS01045	COG0573	inorganic phosphate transmembrane transporter activity
CP523_RS01050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP523_RS01055	COG5002	protein histidine kinase activity
CP523_RS01060	COG0745	RESPONSE REGULATOR receiver
CP523_RS01065	COG1496	oxidoreductase activity
CP523_RS01075	COG1873	PFAM PRC-barrel domain
CP523_RS01080	COG1191	sigma factor activity
CP523_RS01090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP523_RS01105	COG0768	penicillin binding
CP523_RS01115	COG0826	peptidase U32
CP523_RS01120	COG4122	O-methyltransferase activity
CP523_RS01125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP523_RS01130	COG1217	gtp-binding protein TYPA
CP523_RS01135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP523_RS01140	COG0735	belongs to the Fur family
CP523_RS01160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP523_RS01165	COG0628	permease
CP523_RS01180	COG0822	iron-sulfur transferase activity
CP523_RS01190	COG1959	2 iron, 2 sulfur cluster binding
CP523_RS01195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CP523_RS01215	COG0825	malonyl-CoA metabolic process
CP523_RS01225	COG0439	Biotin carboxylase
CP523_RS01235	COG0511	ligase activity, forming carbon-carbon bonds
CP523_RS01240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP523_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
CP523_RS01250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CP523_RS01265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP523_RS01285	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP523_RS01285	COG2878	Part of a membrane complex involved in electron transport
CP523_RS01290	COG4657	Part of a membrane complex involved in electron transport
CP523_RS01295	COG4660	Part of a membrane complex involved in electron transport
CP523_RS01305	COG4658	electron transport chain
CP523_RS01310	COG4656	Part of a membrane complex involved in electron transport
CP523_RS01325	COG0653	protein targeting
CP523_RS01330	COG0542	response to heat
CP523_RS01335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP523_RS01345	COG0768	penicillin binding
CP523_RS01360	COG0737	Belongs to the 5'-nucleotidase family
CP523_RS01370	COG0534	Mate efflux family protein
CP523_RS01375	COG0531	amino acid
CP523_RS01380	COG0534	Mate efflux family protein
CP523_RS01400	COG0840	transmembrane signaling receptor activity
CP523_RS01480	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CP523_RS01505	COG1447	Phosphotransferase system cellobiose-specific component IIA
CP523_RS01590	COG0095	Lipoate-protein ligase
CP523_RS01630	COG2801	Transposase and inactivated derivatives
CP523_RS01640	COG3328	transposase activity
CP523_RS01645	COG3328	transposase activity
CP523_RS01650	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CP523_RS01700	COG0726	polysaccharide deacetylase
CP523_RS01710	COG0745	RESPONSE REGULATOR receiver
CP523_RS01715	COG5002	protein histidine kinase activity
CP523_RS01765	COG0151	Belongs to the GarS family
CP523_RS01775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CP523_RS01780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP523_RS01785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CP523_RS01790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP523_RS01795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CP523_RS01800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP523_RS01805	COG0586	Pfam SNARE associated Golgi protein
CP523_RS01840	COG1428	Deoxynucleoside kinase
CP523_RS01860	COG1073	alpha beta
CP523_RS01865	COG1404	Belongs to the peptidase S8 family
CP523_RS01885	COG0492	ferredoxin-NADP+ reductase activity
CP523_RS01895	COG1132	(ABC) transporter
CP523_RS01915	COG0765	amino acid transport
CP523_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP523_RS01925	COG2996	Protein conserved in bacteria
CP523_RS01945	COG1522	sequence-specific DNA binding
CP523_RS01950	COG2155	Conserved Protein
CP523_RS02000	COG0248	Ppx GppA phosphatase
CP523_RS02020	COG0010	Belongs to the arginase family
CP523_RS02050	COG3842	ATPase activity
CP523_RS02055	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP523_RS02060	COG1177	transmembrane transport
CP523_RS02075	COG1254	Belongs to the acylphosphatase family
CP523_RS02080	COG1115	amino acid carrier protein
CP523_RS02090	COG0561	phosphatase activity
CP523_RS02095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP523_RS02110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP523_RS02120	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CP523_RS02125	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP523_RS02130	COG1609	Transcriptional regulator
CP523_RS02150	COG2384	SAM-dependent methyltransferase
CP523_RS02155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP523_RS02160	COG0358	DNA primase activity
CP523_RS02175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP523_RS02175	COG0574	Belongs to the PEP-utilizing enzyme family
CP523_RS02180	COG0517	IMP dehydrogenase activity
CP523_RS02195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP523_RS02200	COG0295	cytidine deaminase activity
CP523_RS02205	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CP523_RS02215	COG1480	7TM receptor with intracellular HD hydrolase
CP523_RS02235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CP523_RS02240	COG0537	adenosine 5'-monophosphoramidase activity
CP523_RS02245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP523_RS02250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CP523_RS02260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CP523_RS02270	COG0484	heat shock protein binding
CP523_RS02280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP523_RS02290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP523_RS02305	COG0481	GTPase activity
CP523_RS02320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CP523_RS02325	COG0268	Binds directly to 16S ribosomal RNA
CP523_RS02330	COG1466	dna polymerase III delta subunit
CP523_RS02335	COG2333	competence protein COMEC
CP523_RS02335	COG0658	competence protein
CP523_RS02350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP523_RS02365	COG2172	sigma factor antagonist activity
CP523_RS02375	COG1067	ATP-dependent peptidase activity
CP523_RS02385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP523_RS02395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP523_RS02430	COG1509	lysine 2,3-aminomutase activity
CP523_RS02450	COG4106	trans-aconitate 2-methyltransferase activity
CP523_RS02480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP523_RS02485	COG0393	Putative heavy-metal-binding
CP523_RS02500	COG4786	Flagellar basal body rod
CP523_RS02515	COG1191	sigma factor activity
CP523_RS02525	COG0455	bacterial-type flagellum organization
CP523_RS02530	COG1419	protein localization to endoplasmic reticulum
CP523_RS02535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CP523_RS02540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CP523_RS02550	COG1338	Plays a role in the flagellum-specific transport system
CP523_RS02575	COG1582	Flagellar protein (FlbD)
CP523_RS02580	COG4786	Flagellar basal body rod
CP523_RS02580	COG4786	Flagellar basal body rod
CP523_RS02590	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CP523_RS02605	COG1157	protein secretion by the type III secretion system
CP523_RS02615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CP523_RS02625	COG1677	Flagellar hook-basal body complex protein FliE
CP523_RS02635	COG1815	bacterial-type flagellum-dependent cell motility
CP523_RS02640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CP523_RS02650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CP523_RS02655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CP523_RS02660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CP523_RS02675	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CP523_RS02695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CP523_RS02710	COG1256	bacterial-type flagellum assembly
CP523_RS02710	COG4786	Flagellar basal body rod
CP523_RS02725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CP523_RS02725	COG1776	CheC inhibitor of MCP methylation
CP523_RS02730	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CP523_RS02740	COG2201	protein-glutamate methylesterase activity
CP523_RS02745	COG1776	CheC inhibitor of MCP methylation
CP523_RS02750	COG2198	Histidine kinase
CP523_RS02750	COG0643	Histidine kinase
CP523_RS02755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CP523_RS02760	COG2201	protein-glutamate methylesterase activity
CP523_RS02770	COG0835	chemotaxis
CP523_RS02790	COG0436	Aminotransferase
CP523_RS02795	COG0613	PHP domain protein
CP523_RS02815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP523_RS02825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CP523_RS02825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CP523_RS02835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP523_RS02840	COG0187	DNA topoisomerase II activity
CP523_RS02845	COG1215	transferase activity, transferring glycosyl groups
CP523_RS02850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP523_RS02865	COG0705	Rhomboid family
CP523_RS02865	COG0457	Tetratricopeptide repeat
CP523_RS02870	COG1164	Oligoendopeptidase f
CP523_RS02885	COG1121	(ABC) transporter
CP523_RS02890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP523_RS02900	COG1971	Probably functions as a manganese efflux pump
CP523_RS02905	COG0205	6-phosphofructokinase activity
CP523_RS02910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP523_RS02925	COG0577	efflux transmembrane transporter activity
CP523_RS02930	COG1136	(ABC) transporter
CP523_RS02935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP523_RS02940	COG0488	(ABC) transporter
CP523_RS02945	COG3328	transposase activity
CP523_RS02950	COG3328	transposase activity
CP523_RS02955	COG0756	dUTP diphosphatase activity
CP523_RS02970	COG2233	PERMEase
CP523_RS02985	COG0534	Mate efflux family protein
CP523_RS03015	COG0561	phosphatase activity
CP523_RS03020	COG0037	tRNA processing
CP523_RS03040	COG0277	FAD linked oxidase domain protein
CP523_RS03045	COG1966	Carbon starvation protein
CP523_RS03050	COG3279	Response regulator of the LytR AlgR family
CP523_RS03055	COG3275	phosphorelay sensor kinase activity
CP523_RS03065	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CP523_RS03080	COG0697	spore germination
CP523_RS03085	COG1396	sequence-specific DNA binding
CP523_RS03115	COG2267	carboxylic ester hydrolase activity
CP523_RS03130	COG0488	(ABC) transporter
CP523_RS03160	COG0251	oxidation-reduction process
CP523_RS03165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP523_RS03180	COG2116	formate transmembrane transporter activity
CP523_RS03195	COG0113	porphobilinogen synthase activity
CP523_RS03205	COG0181	hydroxymethylbilane synthase activity
CP523_RS03245	COG0432	Pfam Uncharacterised protein family UPF0047
CP523_RS03250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP523_RS03270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CP523_RS03280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP523_RS03290	COG0366	Alpha amylase catalytic
CP523_RS03295	COG2508	Transcriptional regulator
CP523_RS03310	COG4753	response regulator
CP523_RS03310	COG2207	Transcriptional regulator
CP523_RS03315	COG2972	Histidine kinase
CP523_RS03320	COG1285	pathogenesis
CP523_RS03325	COG3842	ATPase activity
CP523_RS03335	COG1840	ABC-type Fe3 transport system, periplasmic component
CP523_RS03340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP523_RS03345	COG0561	phosphatase activity
CP523_RS03365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP523_RS03380	COG4978	Transcriptional regulator
CP523_RS03380	COG0789	Transcriptional regulator
CP523_RS03390	COG0584	glycerophosphoryl diester phosphodiesterase
CP523_RS03405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP523_RS03405	COG4451	ribulose bisphosphate carboxylase, small
CP523_RS03425	COG1054	Belongs to the UPF0176 family
CP523_RS03430	COG2268	Band 7 protein
CP523_RS03445	COG1131	(ABC) transporter
CP523_RS03450	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP523_RS03455	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP523_RS03460	COG3845	ABC transporter
CP523_RS03465	COG1744	ABC transporter substrate-binding protein PnrA-like
CP523_RS03475	COG0395	ABC-type sugar transport system, permease component
CP523_RS03480	COG1175	transmembrane transport
CP523_RS03510	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP523_RS03515	COG1129	ABC transporter
CP523_RS03545	COG2207	Transcriptional regulator
CP523_RS03545	COG4753	response regulator
CP523_RS03550	COG4251	negative regulation of phosphorylation
CP523_RS03565	COG0577	efflux transmembrane transporter activity
CP523_RS03570	COG1136	(ABC) transporter
CP523_RS03575	COG2205	protein histidine kinase activity
CP523_RS03580	COG0745	RESPONSE REGULATOR receiver
CP523_RS03585	COG0419	ATPase involved in DNA repair
CP523_RS03590	COG0420	3'-5' exonuclease activity
CP523_RS03595	COG1053	succinate dehydrogenase
CP523_RS03600	COG4869	propanediol catabolic process
CP523_RS03605	COG0840	transmembrane signaling receptor activity
CP523_RS03610	COG0494	nUDIX hydrolase
CP523_RS03630	COG1404	Belongs to the peptidase S8 family
CP523_RS03640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP523_RS03655	COG0148	phosphopyruvate hydratase activity
CP523_RS03665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS03665	COG1263	PTS System
CP523_RS03665	COG2190	(PTS) system
CP523_RS03670	COG0366	Alpha amylase catalytic
CP523_RS03675	COG1609	Transcriptional regulator
CP523_RS03680	COG0840	transmembrane signaling receptor activity
CP523_RS03690	COG0577	efflux transmembrane transporter activity
CP523_RS03690	COG1136	(ABC) transporter
CP523_RS03720	COG0531	amino acid
CP523_RS03725	COG1982	Orn Lys Arg decarboxylase major
CP523_RS03730	COG3835	regulator
CP523_RS03745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP523_RS03755	COG1473	amidohydrolase
CP523_RS03760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP523_RS03810	COG0584	glycerophosphoryl diester phosphodiesterase
CP523_RS03815	COG1959	2 iron, 2 sulfur cluster binding
CP523_RS03820	COG1472	Belongs to the glycosyl hydrolase 3 family
CP523_RS03825	COG0493	'glutamate synthase
CP523_RS03825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CP523_RS03845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP523_RS03850	COG0557	exoribonuclease II activity
CP523_RS03865	COG0148	phosphopyruvate hydratase activity
CP523_RS03870	COG0577	efflux transmembrane transporter activity
CP523_RS03870	COG1136	(ABC) transporter
CP523_RS03900	COG1609	Transcriptional regulator
CP523_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
CP523_RS03925	COG1862	Preprotein translocase
CP523_RS03935	COG3716	PTS system mannose fructose sorbose family IID component
CP523_RS03945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS03950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CP523_RS03955	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CP523_RS03965	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CP523_RS03985	COG0126	phosphoglycerate kinase activity
CP523_RS03995	COG2390	Transcriptional regulator
CP523_RS04000	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CP523_RS04010	COG1307	EDD domain protein, DegV family
CP523_RS04020	COG1533	DNA photolyase activity
CP523_RS04025	COG0561	phosphatase activity
CP523_RS04030	COG2720	vancomycin resistance protein
CP523_RS04040	COG5002	protein histidine kinase activity
CP523_RS04050	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP523_RS04060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CP523_RS04070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CP523_RS04075	COG1045	serine acetyltransferase
CP523_RS04080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP523_RS04085	COG2239	Acts as a magnesium transporter
CP523_RS04095	COG1597	lipid kinase activity
CP523_RS04100	COG1183	phosphatidylcholine synthase activity
CP523_RS04120	COG2719	SpoVR family
CP523_RS04125	COG2718	Belongs to the UPF0229 family
CP523_RS04130	COG2766	serine protein kinase
CP523_RS04135	COG3250	beta-galactosidase activity
CP523_RS04140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP523_RS04140	COG3064	Membrane
CP523_RS04140	COG3583	domain protein
CP523_RS04145	COG0514	ATP-dependent DNA helicase (RecQ)
CP523_RS04150	COG2199	diguanylate cyclase activity
CP523_RS04150	COG2203	Gaf domain
CP523_RS04155	COG0546	phosphoglycolate phosphatase activity
CP523_RS04160	COG0785	Cytochrome C biogenesis protein
CP523_RS04185	COG3118	belongs to the thioredoxin family
CP523_RS04190	COG1126	abc transporter atp-binding protein
CP523_RS04210	COG0840	transmembrane signaling receptor activity
CP523_RS04225	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP523_RS04225	COG3291	Pkd domain containing protein
CP523_RS04230	COG2188	Transcriptional regulator
CP523_RS04235	COG1131	(ABC) transporter
CP523_RS04280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP523_RS04285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP523_RS04300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP523_RS04300	COG0723	plastoquinol--plastocyanin reductase activity
CP523_RS04335	COG1695	Transcriptional regulator
CP523_RS04340	COG0772	Belongs to the SEDS family
CP523_RS04345	COG0596	Alpha beta hydrolase
CP523_RS04355	COG3279	Response regulator of the LytR AlgR family
CP523_RS04360	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP523_RS04360	COG0392	lysyltransferase activity
CP523_RS04380	COG4509	Sortase family
CP523_RS04385	COG1595	DNA-templated transcription, initiation
CP523_RS04415	COG0681	Belongs to the peptidase S26 family
CP523_RS04420	COG2378	regulation of single-species biofilm formation
CP523_RS04425	COG2199	diguanylate cyclase activity
CP523_RS04425	COG2203	Gaf domain
CP523_RS04475	COG1131	(ABC) transporter
CP523_RS04485	COG1595	DNA-templated transcription, initiation
CP523_RS04495	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CP523_RS04535	COG1136	(ABC) transporter
CP523_RS04585	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CP523_RS04595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP523_RS04600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP523_RS04605	COG1595	DNA-templated transcription, initiation
CP523_RS04620	COG0840	transmembrane signaling receptor activity
CP523_RS04650	COG0515	serine threonine protein kinase
CP523_RS04650	COG2815	serine threonine protein kinase
CP523_RS04655	COG3421	Type III restriction
CP523_RS04660	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CP523_RS04745	COG0642	Histidine kinase
CP523_RS04750	COG0745	RESPONSE REGULATOR receiver
CP523_RS04760	COG1136	(ABC) transporter
CP523_RS04805	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CP523_RS04835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP523_RS04870	COG1263	PTS System
CP523_RS04870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS04940	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP523_RS04940	COG3291	Pkd domain containing protein
CP523_RS04975	COG0489	protein tyrosine kinase activity
CP523_RS04985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP523_RS04990	COG4193	domain, Protein
CP523_RS04990	COG5263	repeat protein
CP523_RS05030	COG2801	Transposase and inactivated derivatives
CP523_RS05065	COG5434	Belongs to the glycosyl hydrolase 28 family
CP523_RS05070	COG1045	serine acetyltransferase
CP523_RS05080	COG0728	peptidoglycan biosynthetic process
CP523_RS05085	COG0438	transferase activity, transferring glycosyl groups
CP523_RS05090	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CP523_RS05100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CP523_RS05105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP523_RS05110	COG4464	protein tyrosine phosphatase activity
CP523_RS05115	COG0489	protein tyrosine kinase activity
CP523_RS05120	COG3944	biosynthesis protein
CP523_RS05145	COG0561	phosphatase activity
CP523_RS05155	COG2223	nitrite transmembrane transporter activity
CP523_RS05175	COG5002	protein histidine kinase activity
CP523_RS05180	COG1136	(ABC) transporter
CP523_RS05180	COG0577	efflux transmembrane transporter activity
CP523_RS05195	COG2030	dehydratase
CP523_RS05210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CP523_RS05235	COG3958	Transketolase
CP523_RS05240	COG3959	Transketolase, thiamine diphosphate binding domain
CP523_RS05265	COG3037	sugar-specific permease SgaT UlaA
CP523_RS05270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP523_RS05285	COG1349	DNA-binding transcription factor activity
CP523_RS05290	COG0406	alpha-ribazole phosphatase activity
CP523_RS05305	COG0561	phosphatase activity
CP523_RS05320	COG4509	Sortase family
CP523_RS05345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP523_RS05365	COG3853	Toxic anion resistance protein (TelA)
CP523_RS05380	COG1358	cellular component organization or biogenesis
CP523_RS05410	COG1132	(ABC) transporter
CP523_RS05420	COG1482	cell wall glycoprotein biosynthetic process
CP523_RS05425	COG1940	carbohydrate kinase activity
CP523_RS05435	COG2723	6-phospho-beta-galactosidase activity
CP523_RS05440	COG1653	transport
CP523_RS05460	COG1653	transport
CP523_RS05465	COG0383	alpha-mannosidase activity
CP523_RS05470	COG0395	ABC-type sugar transport system, permease component
CP523_RS05475	COG4209	transmembrane transport
CP523_RS05490	COG2732	(Barnase) inhibitor
CP523_RS05665	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP523_RS05710	COG4974	Belongs to the 'phage' integrase family
CP523_RS05740	COG4974	Belongs to the 'phage' integrase family
CP523_RS05790	COG3409	Peptidoglycan-binding domain 1 protein
CP523_RS05790	COG3501	Rhs element vgr protein
CP523_RS05800	COG4753	response regulator
CP523_RS05800	COG2207	Transcriptional regulator
CP523_RS05805	COG2972	Histidine kinase
CP523_RS05835	COG0561	phosphatase activity
CP523_RS05845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP523_RS05845	COG3711	transcriptional antiterminator
CP523_RS05855	COG5002	protein histidine kinase activity
CP523_RS05860	COG0277	FAD linked oxidase domain protein
CP523_RS05865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP523_RS05870	COG2086	electron transfer activity
CP523_RS05875	COG1620	l-lactate permease
CP523_RS05880	COG2186	Transcriptional regulator
CP523_RS05905	COG3459	Glycosyltransferase 36 associated
CP523_RS05910	COG1136	(ABC) transporter
CP523_RS05930	COG1362	aminopeptidase activity
CP523_RS05935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CP523_RS05955	COG1131	(ABC) transporter
CP523_RS05960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP523_RS05975	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP523_RS05985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP523_RS05995	COG2971	BadF BadG BcrA BcrD
CP523_RS06005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CP523_RS06020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CP523_RS06025	COG1447	Phosphotransferase system cellobiose-specific component IIA
CP523_RS06030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP523_RS06045	COG1737	Transcriptional regulator
CP523_RS06055	COG1126	abc transporter atp-binding protein
CP523_RS06060	COG0765	amino acid transport
CP523_RS06065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP523_RS06075	COG0840	transmembrane signaling receptor activity
CP523_RS06080	COG3973	AAA domain
CP523_RS06085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP523_RS06095	COG0681	Belongs to the peptidase S26 family
CP523_RS06105	COG0019	diaminopimelate decarboxylase activity
CP523_RS06125	COG3328	transposase activity
CP523_RS06165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CP523_RS06175	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP523_RS06180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CP523_RS06185	COG0659	secondary active sulfate transmembrane transporter activity
CP523_RS06195	COG3279	Response regulator of the LytR AlgR family
CP523_RS06210	COG3328	transposase activity
CP523_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
CP523_RS06225	COG1125	glycine betaine transport
CP523_RS06225	COG0517	IMP dehydrogenase activity
CP523_RS06230	COG1732	Glycine betaine
CP523_RS06235	COG2814	Major facilitator Superfamily
CP523_RS06260	COG1136	(ABC) transporter
CP523_RS06280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP523_RS06290	COG1696	Membrane protein involved in D-alanine export
CP523_RS06310	COG2205	protein histidine kinase activity
CP523_RS06355	COG0469	pyruvate kinase activity
CP523_RS06370	COG1481	regulation of sporulation
CP523_RS06375	COG0577	efflux transmembrane transporter activity
CP523_RS06380	COG1136	(ABC) transporter
CP523_RS06415	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP523_RS06425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP523_RS06435	COG0322	excinuclease ABC activity
CP523_RS06440	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CP523_RS06445	COG0768	penicillin binding
CP523_RS06470	COG4565	transcriptional regulatory protein
CP523_RS06475	COG3290	protein histidine kinase activity
CP523_RS06480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP523_RS06495	COG0556	nucleotide-excision repair
CP523_RS06505	COG3409	Peptidoglycan-binding domain 1 protein
CP523_RS06505	COG0793	Belongs to the peptidase S41A family
CP523_RS06510	COG2177	Part of the ABC transporter FtsEX involved in
CP523_RS06515	COG2884	Cell division ATP-binding protein ftsE
CP523_RS06520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CP523_RS06525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CP523_RS06530	COG3958	Transketolase
CP523_RS06535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP523_RS06540	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP523_RS06555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CP523_RS06555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CP523_RS06560	COG0736	holo-[acyl-carrier-protein] synthase activity
CP523_RS06570	COG0426	domain, Protein
CP523_RS06575	COG0629	single-stranded DNA binding
CP523_RS06580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP523_RS06585	COG1295	ribonuclease BN
CP523_RS06595	COG1199	ATP-dependent helicase activity
CP523_RS06605	COG2002	toxin-antitoxin pair type II binding
CP523_RS06610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CP523_RS06615	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CP523_RS06640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP523_RS06645	COG3328	transposase activity
CP523_RS06655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CP523_RS06700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP523_RS06730	COG1058	Belongs to the CinA family
CP523_RS06730	COG1546	Belongs to the CinA family
CP523_RS06740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP523_RS06745	COG0463	Glycosyl transferase, family 2
CP523_RS06760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CP523_RS06765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP523_RS06805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP523_RS06820	COG0058	SHG alpha-glucan phosphorylase activity
CP523_RS06895	COG0789	Transcriptional regulator
CP523_RS06900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP523_RS06910	COG0058	SHG alpha-glucan phosphorylase activity
CP523_RS06935	COG2190	(PTS) system
CP523_RS06935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS06935	COG1263	PTS System
CP523_RS06950	COG0833	amino acid
CP523_RS06980	COG1653	transport
CP523_RS06985	COG5426	von Willebrand factor, type A
CP523_RS06990	COG0395	ABC-type sugar transport system, permease component
CP523_RS07005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CP523_RS07015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP523_RS07035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP523_RS07070	COG1131	(ABC) transporter
CP523_RS07075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP523_RS07090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP523_RS07095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CP523_RS07125	COG1053	succinate dehydrogenase
CP523_RS07135	COG3290	protein histidine kinase activity
CP523_RS07140	COG0590	tRNA wobble adenosine to inosine editing
CP523_RS07145	COG4536	flavin adenine dinucleotide binding
CP523_RS07155	COG0204	Acyl-transferase
CP523_RS07160	COG0534	Mate efflux family protein
CP523_RS07170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP523_RS07175	COG0513	Belongs to the DEAD box helicase family
CP523_RS07185	COG1959	2 iron, 2 sulfur cluster binding
CP523_RS07195	COG0588	phosphoglycerate mutase activity
CP523_RS07205	COG0697	spore germination
CP523_RS07245	COG4978	Transcriptional regulator
CP523_RS07245	COG0789	Transcriptional regulator
CP523_RS07280	COG2188	Transcriptional regulator
CP523_RS07285	COG0366	Alpha amylase catalytic
CP523_RS07290	COG1263	PTS System
CP523_RS07290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS07300	COG5002	protein histidine kinase activity
CP523_RS07305	COG0745	RESPONSE REGULATOR receiver
CP523_RS07345	COG0556	nucleotide-excision repair
CP523_RS07350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP523_RS07410	COG0653	protein targeting
CP523_RS07415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CP523_RS07440	COG1404	Belongs to the peptidase S8 family
CP523_RS07445	COG0739	heme binding
CP523_RS07520	COG2081	HI0933 family
CP523_RS07545	COG0281	malic enzyme
CP523_RS07550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP523_RS07560	COG0305	Participates in initiation and elongation during chromosome replication
CP523_RS07565	COG1067	ATP-dependent peptidase activity
CP523_RS07565	COG0470	DNA polymerase III
CP523_RS07570	COG0359	binds to the 23S rRNA
CP523_RS07575	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CP523_RS07595	COG0360	Binds together with S18 to 16S ribosomal RNA
CP523_RS07605	COG0668	transmembrane transport
CP523_RS07635	COG1475	DNA binding
CP523_RS07640	COG1192	Involved in chromosome partitioning
CP523_RS07645	COG1475	DNA binding
CP523_RS07655	COG0445	tRNA wobble uridine modification
CP523_RS07660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CP523_RS07665	COG1847	R3H domain protein
CP523_RS07680	COG0594	ribonuclease P activity
CP523_RS07685	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP523_RS07695	COG0592	DNA-directed DNA polymerase activity
CP523_RS07715	COG0187	DNA topoisomerase II activity
CP523_RS07775	COG1116	anion transmembrane transporter activity
CP523_RS07780	COG1116	anion transmembrane transporter activity
CP523_RS07825	COG1827	regulation of RNA biosynthetic process
CP523_RS07840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP523_RS07850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP523_RS07855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP523_RS07860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP523_RS07880	COG1940	carbohydrate kinase activity
CP523_RS07890	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CP523_RS07920	COG1376	ErfK ybiS ycfS ynhG family protein
CP523_RS07930	COG5002	protein histidine kinase activity
CP523_RS07940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP523_RS07950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP523_RS07955	COG1120	ATPase activity
CP523_RS07970	COG1486	melibiose metabolic process
CP523_RS08000	COG0488	(ABC) transporter
CP523_RS08005	COG0733	neurotransmitter:sodium symporter activity
CP523_RS08010	COG1272	protein, Hemolysin III
CP523_RS08030	COG3314	Sporulation integral membrane protein YlbJ
CP523_RS08050	COG2949	membrane
CP523_RS08060	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CP523_RS08065	COG4221	oxidoreductase activity
CP523_RS08070	COG0561	phosphatase activity
CP523_RS08080	COG1668	transmembrane transport
CP523_RS08085	COG4555	ABC transporter
CP523_RS08100	COG3328	transposase activity
CP523_RS08125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP523_RS08135	COG3800	Transcriptional regulator
CP523_RS08135	COG1396	sequence-specific DNA binding
CP523_RS08155	COG3949	Membrane
CP523_RS08165	COG1242	4 iron, 4 sulfur cluster binding
CP523_RS08185	COG2340	Cysteine-rich secretory protein family
CP523_RS08220	COG1846	Transcriptional regulator
CP523_RS08235	COG2715	membrane protein required for spore maturation
CP523_RS08240	COG0700	Nucleoside recognition
CP523_RS08270	COG0006	proline dipeptidase activity
CP523_RS08275	COG1757	Na H antiporter
CP523_RS08280	COG0006	proline dipeptidase activity
CP523_RS08310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP523_RS08315	COG0084	hydrolase, TatD family'
CP523_RS08320	COG3583	domain protein
CP523_RS08320	COG3584	3D domain protein
CP523_RS08325	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CP523_RS08355	COG1141	Ferredoxin
CP523_RS08385	COG1470	cell adhesion involved in biofilm formation
CP523_RS08390	COG1328	CTP reductase activity
CP523_RS08395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP523_RS08400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP523_RS08425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP523_RS08430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP523_RS08435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP523_RS08440	COG1120	ATPase activity
CP523_RS08465	COG1131	(ABC) transporter
CP523_RS08470	COG0017	Asparaginyl-tRNA synthetase
CP523_RS08485	COG0006	proline dipeptidase activity
CP523_RS08490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP523_RS08495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP523_RS08515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP523_RS08525	COG0745	RESPONSE REGULATOR receiver
CP523_RS08530	COG5002	protein histidine kinase activity
CP523_RS08530	COG3850	Histidine kinase
CP523_RS08535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP523_RS08545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CP523_RS08550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CP523_RS08555	COG2002	toxin-antitoxin pair type II binding
CP523_RS08560	COG2244	polysaccharide biosynthetic process
CP523_RS08565	COG3956	TIGRFAM MazG family protein
CP523_RS08575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CP523_RS08595	COG1098	S1 RNA binding domain
CP523_RS08640	COG0037	tRNA processing
CP523_RS08650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP523_RS08665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CP523_RS08670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP523_RS08695	COG0423	glycine-tRNA ligase activity
CP523_RS08745	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP523_RS08770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP523_RS08775	COG3870	Protein conserved in bacteria
CP523_RS08785	COG1774	PSP1 C-terminal conserved region
CP523_RS08810	COG0542	response to heat
CP523_RS08840	COG2188	Transcriptional regulator
CP523_RS08850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CP523_RS08855	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP523_RS08865	COG4956	integral membrane protein (PIN domain superfamily)
CP523_RS08875	COG0442	prolyl-tRNA aminoacylation
CP523_RS08890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP523_RS08915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP523_RS08920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP523_RS08925	COG0250	Participates in transcription elongation, termination and antitermination
CP523_RS08955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP523_RS08960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP523_RS08970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP523_RS09015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP523_RS09020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP523_RS09040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP523_RS09050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP523_RS09055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP523_RS09060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP523_RS09090	COG0200	Binds to the 23S rRNA
CP523_RS09095	COG0201	protein transport
CP523_RS09115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP523_RS09120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP523_RS09130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP523_RS09150	COG1122	ATPase activity
CP523_RS09155	COG1122	ATPase activity
CP523_RS09160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CP523_RS09180	COG1283	sodium-dependent phosphate transmembrane transporter activity
CP523_RS09195	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP523_RS09210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CP523_RS09220	COG5002	protein histidine kinase activity
CP523_RS09225	COG1393	Belongs to the ArsC family
CP523_RS09230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP523_RS09235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP523_RS09245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP523_RS09250	COG2059	Chromate
CP523_RS09255	COG2059	Chromate
CP523_RS09265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP523_RS09270	COG3773	Cell wall hydrolase
CP523_RS09270	COG3409	Peptidoglycan-binding domain 1 protein
CP523_RS09280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CP523_RS09290	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CP523_RS09295	COG0280	phosphate acetyltransferase
CP523_RS09310	COG4496	protein, YerC YecD
CP523_RS09315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP523_RS09335	COG0531	amino acid
CP523_RS09340	COG3250	beta-galactosidase activity
CP523_RS09355	COG1136	(ABC) transporter
CP523_RS09365	COG0577	efflux transmembrane transporter activity
CP523_RS09395	COG5002	protein histidine kinase activity
CP523_RS09425	COG0561	phosphatase activity
CP523_RS09430	COG1376	ErfK ybiS ycfS ynhG family protein
CP523_RS09455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP523_RS09460	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP523_RS09460	COG3408	Glycogen debranching enzyme
CP523_RS09465	COG0640	Transcriptional regulator
CP523_RS09515	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP523_RS09520	COG3764	Sortase (surface protein transpeptidase)
CP523_RS09530	COG1187	pseudouridine synthase activity
CP523_RS09540	COG1012	belongs to the aldehyde dehydrogenase family
CP523_RS09545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP523_RS09550	COG0662	Cupin 2, conserved barrel domain protein
CP523_RS09550	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CP523_RS09565	COG2217	Heavy metal translocating P-type atpase
CP523_RS09575	COG1024	Enoyl-CoA hydratase
CP523_RS09580	COG1960	acyl-CoA dehydrogenase activity
CP523_RS09585	COG2086	electron transfer activity
CP523_RS09595	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP523_RS09615	COG2188	Transcriptional regulator
CP523_RS09620	COG2222	sugar isomerase
CP523_RS09635	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CP523_RS09645	COG0398	Pfam SNARE associated Golgi protein
CP523_RS09655	COG0459	protein refolding
CP523_RS09665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CP523_RS09670	COG0516	GMP reductase activity
CP523_RS09670	COG0517	IMP dehydrogenase activity
CP523_RS09675	COG0519	Catalyzes the synthesis of GMP from XMP
CP523_RS09685	COG1671	Belongs to the UPF0178 family
CP523_RS09695	COG0741	lytic transglycosylase activity
CP523_RS09700	COG1187	pseudouridine synthase activity
CP523_RS09730	COG1136	(ABC) transporter
CP523_RS09730	COG0577	efflux transmembrane transporter activity
CP523_RS09740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP523_RS09880	COG3142	Participates in the control of copper homeostasis
CP523_RS09920	COG0745	RESPONSE REGULATOR receiver
CP523_RS09925	COG5002	protein histidine kinase activity
CP523_RS09935	COG0312	modulator of DNA gyrase
CP523_RS09940	COG0312	modulator of DNA gyrase
CP523_RS09945	COG1368	sulfuric ester hydrolase activity
CP523_RS09950	COG0492	ferredoxin-NADP+ reductase activity
CP523_RS09965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP523_RS09975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP523_RS09980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CP523_RS09990	COG3192	ethanolamine utilization protein
CP523_RS10015	COG0583	DNA-binding transcription factor activity
CP523_RS10060	COG4466	Protein conserved in bacteria
CP523_RS10070	COG4242	Belongs to the peptidase S51 family
CP523_RS10075	COG0189	ligase activity
CP523_RS10075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP523_RS10110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP523_RS10115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP523_RS10135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP523_RS10145	COG0009	L-threonylcarbamoyladenylate synthase
CP523_RS10150	COG0698	ribose 5-phosphate isomerase
CP523_RS10155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP523_RS10165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CP523_RS10170	COG0183	Belongs to the thiolase family
CP523_RS10180	COG0356	it plays a direct role in the translocation of protons across the membrane
CP523_RS10215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP523_RS10240	COG2385	sporulation resulting in formation of a cellular spore
CP523_RS10250	COG1609	Transcriptional regulator
CP523_RS10255	COG1077	Cell shape determining protein MreB Mrl
CP523_RS10305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP523_RS10315	COG1040	competence protein
CP523_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP523_RS10355	COG1120	ATPase activity
CP523_RS10370	COG1131	(ABC) transporter
CP523_RS10395	COG2801	Transposase and inactivated derivatives
CP523_RS10410	COG2183	response to ionizing radiation
CP523_RS10415	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CP523_RS10420	COG0456	acetyltransferase
CP523_RS10425	COG1214	PFAM Peptidase M22, glycoprotease
CP523_RS10430	COG0802	atpase or kinase
CP523_RS10445	COG2070	2-Nitropropane dioxygenase
CP523_RS10455	COG3292	Two component regulator propeller
CP523_RS10455	COG0745	RESPONSE REGULATOR receiver
CP523_RS10455	COG2205	protein histidine kinase activity
CP523_RS10465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP523_RS10470	COG3711	transcriptional antiterminator
CP523_RS10480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS10480	COG2190	(PTS) system
CP523_RS10480	COG1263	PTS System
CP523_RS10485	COG1272	protein, Hemolysin III
CP523_RS10495	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CP523_RS10495	COG3408	Glycogen debranching enzyme
CP523_RS10520	COG4717	serine-type aminopeptidase activity
CP523_RS10525	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP523_RS10530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CP523_RS10560	COG1842	Phage shock protein A
CP523_RS10575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP523_RS10575	COG0539	negative regulation of cytoplasmic translation
CP523_RS10585	COG2195	Cleaves the N-terminal amino acid of tripeptides
CP523_RS10605	COG1077	Cell shape determining protein MreB Mrl
CP523_RS10625	COG2894	cell division
CP523_RS10635	COG0772	Belongs to the SEDS family
CP523_RS10665	COG1530	ribonuclease E activity
CP523_RS10690	COG1534	Rna-binding protein
CP523_RS10700	COG1713	HD superfamily hydrolase involved in NAD metabolism
CP523_RS10710	COG0564	pseudouridine synthase activity
CP523_RS10715	COG1686	Belongs to the peptidase S11 family
CP523_RS10720	COG1555	photosystem II stabilization
CP523_RS10720	COG1596	polysaccharide export
CP523_RS10745	COG0747	negative chemotaxis
CP523_RS10750	COG0601	transmembrane transport
CP523_RS10755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP523_RS10765	COG4608	Belongs to the ABC transporter superfamily
CP523_RS10770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP523_RS10775	COG3458	cephalosporin-C deacetylase activity
CP523_RS10785	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CP523_RS10795	COG2508	Transcriptional regulator
CP523_RS10805	COG1402	creatininase
CP523_RS10810	COG0402	S-adenosylhomocysteine deaminase activity
CP523_RS10820	COG0840	transmembrane signaling receptor activity
CP523_RS10845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP523_RS10850	COG1760	l-serine dehydratase
CP523_RS10855	COG1760	l-serine dehydratase
CP523_RS10865	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CP523_RS10885	COG1114	Component of the transport system for branched-chain amino acids
CP523_RS10895	COG1316	TRANSCRIPTIONal
CP523_RS10900	COG0463	Glycosyl transferase, family 2
CP523_RS10910	COG1086	Polysaccharide biosynthesis protein
CP523_RS10915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP523_RS10925	COG2089	acid synthase
CP523_RS10935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CP523_RS10980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CP523_RS10980	COG0662	Cupin 2, conserved barrel domain protein
CP523_RS10985	COG0438	transferase activity, transferring glycosyl groups
CP523_RS11000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP523_RS11005	COG1091	dTDP-4-dehydrorhamnose reductase activity
CP523_RS11030	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP523_RS11030	COG2247	cell wall binding repeat
CP523_RS11040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP523_RS11045	COG3842	ATPase activity
CP523_RS11080	COG0697	spore germination
CP523_RS11090	COG2865	translation initiation factor activity
CP523_RS11105	COG3711	transcriptional antiterminator
CP523_RS11115	COG3850	Histidine kinase
CP523_RS11115	COG5002	protein histidine kinase activity
CP523_RS11120	COG0745	RESPONSE REGULATOR receiver
CP523_RS11130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CP523_RS11140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP523_RS11170	COG2205	protein histidine kinase activity
CP523_RS11205	COG2357	RelA SpoT domain protein
CP523_RS11235	COG1263	PTS System
CP523_RS11235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP523_RS11235	COG2190	(PTS) system
CP523_RS11240	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CP523_RS11245	COG1737	Transcriptional regulator
CP523_RS11250	COG2731	YhcH YjgK YiaL family protein
CP523_RS11260	COG0024	Methionine aminopeptidase
CP523_RS11265	COG3328	transposase activity
CP523_RS11285	COG0495	leucyl-tRNA aminoacylation
CP523_RS11335	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CP523_RS11345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP523_RS11350	COG1120	ATPase activity
CP523_RS11375	COG1592	Rubrerythrin
CP523_RS11375	COG1773	rubredoxin
CP523_RS11380	COG1592	Rubrerythrin
CP523_RS11380	COG1773	rubredoxin
CP523_RS11385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP523_RS11390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CP523_RS11400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP523_RS11405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP523_RS11410	COG0077	Prephenate dehydratase
CP523_RS11410	COG1605	Chorismate mutase
CP523_RS11415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP523_RS11420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP523_RS11425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP523_RS11430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CP523_RS11440	COG0697	spore germination
CP523_RS11445	COG3069	C4-dicarboxylate transmembrane transporter activity
CP523_RS11450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP523_RS11450	COG3711	transcriptional antiterminator
CP523_RS11485	COG4716	Myosin-crossreactive antigen
CP523_RS11500	COG0733	neurotransmitter:sodium symporter activity
CP523_RS11515	COG0789	Transcriptional regulator
CP523_RS11520	COG1937	Protein conserved in bacteria
CP523_RS11555	COG3584	3D domain protein
CP523_RS11555	COG3583	domain protein
CP523_RS11560	COG0165	Argininosuccinate lyase
CP523_RS11570	COG0840	transmembrane signaling receptor activity
CP523_RS11580	COG0671	phosphoesterase, PA-phosphatase related
CP523_RS11600	COG0789	Transcriptional regulator
CP523_RS11630	COG2011	ABC-type metal ion transport system permease component
CP523_RS11635	COG1464	Belongs to the NlpA lipoprotein family
CP523_RS11640	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP523_RS11645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP523_RS11655	COG3339	Conserved Protein
CP523_RS11660	COG0328	RNA-DNA hybrid ribonuclease activity
CP523_RS11680	COG0534	Mate efflux family protein
CP523_RS11685	COG1349	DNA-binding transcription factor activity
CP523_RS11700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP523_RS11710	COG3962	Belongs to the TPP enzyme family
CP523_RS11715	COG0673	inositol 2-dehydrogenase activity
CP523_RS11720	COG1082	Xylose isomerase domain protein TIM barrel
CP523_RS11725	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP523_RS11730	COG0673	inositol 2-dehydrogenase activity
CP523_RS11735	COG2207	Transcriptional regulator
CP523_RS11790	COG4684	Psort location CytoplasmicMembrane, score
CP523_RS11795	COG1131	(ABC) transporter
CP523_RS11815	COG1983	PspC domain protein
CP523_RS11820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP523_RS11835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP523_RS11845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP523_RS11860	COG0739	heme binding
CP523_RS11890	COG1067	ATP-dependent peptidase activity
CP523_RS11890	COG0470	DNA polymerase III
CP523_RS11895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP523_RS11900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CP523_RS11925	COG0735	belongs to the Fur family
CP523_RS11935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CP523_RS11950	COG0849	cell division
CP523_RS11955	COG1473	amidohydrolase
CP523_RS11965	COG2244	polysaccharide biosynthetic process
CP523_RS11970	COG2244	polysaccharide biosynthetic process
CP523_RS12005	COG1269	ATP hydrolysis coupled proton transport
CP523_RS12010	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP523_RS12020	COG1527	subunit (C
CP523_RS12045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP523_RS12060	COG1410	methionine synthase
CP523_RS12060	COG0646	methionine synthase
CP523_RS12075	COG4988	ABC transporter
CP523_RS12080	COG1132	(ABC) transporter
CP523_RS12085	COG2832	Protein of unknown function (DUF454)
CP523_RS12115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP523_RS12115	COG2199	diguanylate cyclase activity
CP523_RS12120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP523_RS12130	COG0494	nUDIX hydrolase
CP523_RS12145	COG5002	protein histidine kinase activity
CP523_RS12150	COG2364	Membrane
CP523_RS12175	COG3328	transposase activity
CP523_RS12200	COG2720	vancomycin resistance protein
CP523_RS12250	COG1114	Component of the transport system for branched-chain amino acids
CP523_RS12260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CP523_RS12260	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CP523_RS12270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CP523_RS12275	COG1447	Phosphotransferase system cellobiose-specific component IIA
CP523_RS12280	COG1486	melibiose metabolic process
CP523_RS12285	COG3394	polysaccharide catabolic process
CP523_RS12295	COG1971	Probably functions as a manganese efflux pump
CP523_RS12300	COG2824	Alkylphosphonate utilization operon protein PhnA
CP523_RS12305	COG2816	NAD+ diphosphatase activity
CP523_RS12310	COG4585	Histidine kinase
CP523_RS12315	COG2197	response regulator
CP523_RS12320	COG1131	(ABC) transporter
CP523_RS12340	COG5599	Phosphatase
CP523_RS12345	COG2378	regulation of single-species biofilm formation
CP523_RS12360	COG0295	cytidine deaminase activity
CP523_RS12385	COG2188	Transcriptional regulator
CP523_RS12395	COG0464	growth
CP523_RS12420	COG0789	Transcriptional regulator
CP523_RS12445	COG1012	belongs to the aldehyde dehydrogenase family
CP523_RS12445	COG1454	alcohol dehydrogenase
CP523_RS12450	COG1882	Formate acetyltransferase
CP523_RS12455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP523_RS12485	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CP523_RS12495	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CP523_RS12500	COG1454	alcohol dehydrogenase
CP523_RS12500	COG1012	belongs to the aldehyde dehydrogenase family
CP523_RS12505	COG4869	propanediol catabolic process
CP523_RS12515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CP523_RS12520	COG3250	beta-galactosidase activity
CP523_RS12555	COG0346	lactoylglutathione lyase activity
CP523_RS12570	COG0305	Participates in initiation and elongation during chromosome replication
CP523_RS12585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CP523_RS12630	COG5002	protein histidine kinase activity
CP523_RS12645	COG0243	molybdopterin cofactor binding
CP523_RS12660	COG1363	Peptidase, m42
CP523_RS12665	COG5002	protein histidine kinase activity
CP523_RS12685	COG0577	efflux transmembrane transporter activity
CP523_RS12685	COG1136	(ABC) transporter
CP523_RS12715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CP523_RS12725	COG0745	RESPONSE REGULATOR receiver
CP523_RS12730	COG0642	Histidine kinase
CP523_RS12745	COG1136	(ABC) transporter
CP523_RS12750	COG0577	efflux transmembrane transporter activity
CP523_RS12760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP523_RS12765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP523_RS12785	COG3655	Transcriptional regulator
CP523_RS12800	COG3835	regulator
CP523_RS12805	COG2610	gluconate transmembrane transporter activity
CP523_RS12810	COG1929	Belongs to the glycerate kinase type-1 family
CP523_RS12815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP523_RS12820	COG1073	alpha beta
CP523_RS12825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP523_RS12835	COG4720	Psort location CytoplasmicMembrane, score
CP523_RS12855	COG3328	transposase activity
CP523_RS12865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP523_RS12870	COG0561	phosphatase activity
CP523_RS12875	COG1846	Transcriptional regulator
CP523_RS12885	COG1132	(ABC) transporter
CP523_RS12890	COG0351	phosphomethylpyrimidine kinase
CP523_RS12890	COG0352	thiamine-phosphate diphosphorylase activity
CP523_RS12895	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CP523_RS12900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CP523_RS12905	COG0352	thiamine-phosphate diphosphorylase activity
CP523_RS12915	COG1621	beta-fructofuranosidase activity
CP523_RS12940	COG0613	PHP domain protein
CP523_RS12945	COG0534	Mate efflux family protein
CP523_RS12955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP523_RS12960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CP523_RS12965	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CP523_RS12980	COG0406	alpha-ribazole phosphatase activity
CP523_RS12990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP523_RS13000	COG0737	Belongs to the 5'-nucleotidase family
CP523_RS13005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP523_RS13010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP523_RS13015	COG1120	ATPase activity
CP523_RS13040	COG0840	transmembrane signaling receptor activity
CP523_RS13055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP523_RS13365	COG3328	transposase activity
CP523_RS13395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP523_RS13410	COG3594	Acyltransferase
CP523_RS13425	COG1803	Methylglyoxal synthase
CP523_RS13435	COG3830	Belongs to the UPF0237 family
CP523_RS13450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP523_RS13455	COG3973	AAA domain
CP523_RS13460	COG0426	domain, Protein
CP523_RS13475	COG1376	ErfK ybiS ycfS ynhG family protein
CP523_RS13480	COG1331	Highly conserved protein containing a thioredoxin domain
CP523_RS13490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CP523_RS13530	COG1362	aminopeptidase activity
CP523_RS13540	COG0613	PHP domain protein
CP523_RS13545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP523_RS13545	COG0512	Glutamine amidotransferase of anthranilate synthase
CP523_RS13555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP523_RS13565	COG1418	mRNA catabolic process
CP523_RS13575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP523_RS13580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP523_RS13580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP523_RS13585	COG3328	transposase activity
CP523_RS13605	COG0745	RESPONSE REGULATOR receiver
CP523_RS13610	COG1131	(ABC) transporter
CP523_RS13625	COG1773	rubredoxin
CP523_RS13625	COG1592	Rubrerythrin
CP523_RS13630	COG0534	Mate efflux family protein
CP523_RS13680	COG2252	PERMEase
CP523_RS13685	COG0531	amino acid
CP523_RS13695	COG0583	DNA-binding transcription factor activity
CP523_RS13730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP523_RS13730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP523_RS13745	COG2264	protein methyltransferase activity
CP523_RS13755	COG1686	Belongs to the peptidase S11 family
CP523_RS13760	COG0726	polysaccharide deacetylase
CP523_RS13765	COG3442	glutamine amidotransferase
CP523_RS13770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CP523_RS13780	COG3292	Two component regulator propeller
CP523_RS13780	COG2205	protein histidine kinase activity
CP523_RS13780	COG0745	RESPONSE REGULATOR receiver
CP523_RS13790	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CP523_RS13795	COG0551	DNA topoisomerase type I activity
CP523_RS13795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP523_RS13800	COG1346	cytolysis
CP523_RS13855	COG1396	sequence-specific DNA binding
CP523_RS13905	COG3546	catalase activity
CP523_RS13915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP523_RS13920	COG1116	anion transmembrane transporter activity
CP523_RS13925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP523_RS13940	COG1968	undecaprenyl-diphosphatase activity
CP523_RS13955	COG3328	transposase activity
CP523_RS13990	COG0167	dihydroorotate dehydrogenase activity
CP523_RS14010	COG1115	amino acid carrier protein
CP523_RS14015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP523_RS14025	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CP523_RS14030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP523_RS14045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP523_RS14050	COG1739	Uncharacterized protein family UPF0029
CP523_RS14085	COG0737	Belongs to the 5'-nucleotidase family
CP523_RS14090	COG2195	Cleaves the N-terminal amino acid of tripeptides
CP523_RS14095	COG0484	heat shock protein binding
CP523_RS14105	COG4129	membrane
CP523_RS14115	COG0307	riboflavin synthase, alpha
CP523_RS14120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP523_RS14120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP523_RS14125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP523_RS14150	COG1660	Displays ATPase and GTPase activities
CP523_RS14160	COG1309	transcriptional regulator
CP523_RS14165	COG2409	Drug exporters of the RND superfamily
CP523_RS14195	COG0632	four-way junction helicase activity
CP523_RS14215	COG1862	Preprotein translocase
CP523_RS14225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP523_RS14230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP523_RS14235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CP523_RS14235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CP523_RS14245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP523_RS14255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP523_RS14260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP523_RS14275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP523_RS14285	COG0514	ATP-dependent DNA helicase (RecQ)
CP523_RS14290	COG1979	alcohol dehydrogenase
CP523_RS14295	COG1937	Protein conserved in bacteria
CP523_RS14305	COG0733	neurotransmitter:sodium symporter activity
CP523_RS14315	COG2966	Psort location CytoplasmicMembrane, score
CP523_RS14330	COG0753	catalase activity
CP523_RS14340	COG0840	transmembrane signaling receptor activity
CP523_RS14345	COG0708	Exodeoxyribonuclease III
CP523_RS14355	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CP523_RS14355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CP523_RS14375	COG1028	Short-chain dehydrogenase reductase Sdr
CP523_RS14380	COG1191	sigma factor activity
CP523_RS14385	COG2755	lipolytic protein G-D-S-L family
CP523_RS14405	COG2239	Acts as a magnesium transporter
CP523_RS14420	COG0745	RESPONSE REGULATOR receiver
CP523_RS14425	COG0612	Peptidase, M16
CP523_RS14430	COG2137	regulation of response to DNA damage stimulus
CP523_RS14445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP523_RS14445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP523_RS14470	COG1234	tRNA 3'-trailer cleavage
CP523_RS14475	COG3023	N-Acetylmuramoyl-L-alanine amidase
CP523_RS14510	COG0601	transmembrane transport
CP523_RS14515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP523_RS14520	COG0444	Belongs to the ABC transporter superfamily
CP523_RS14525	COG4608	Belongs to the ABC transporter superfamily
CP523_RS14530	COG4166	transmembrane transport
CP523_RS14550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP523_RS14555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CP523_RS14565	COG2226	methyltransferase
CP523_RS14585	COG0617	tRNA 3'-terminal CCA addition
CP523_RS14610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP523_RS14615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CP523_RS14620	COG0569	domain protein
CP523_RS14625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP523_RS14630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP523_RS14650	COG3328	transposase activity
CP523_RS14660	COG0826	peptidase U32
CP523_RS14670	COG1193	negative regulation of DNA recombination
CP523_RS14675	COG1683	Conserved Protein
CP523_RS14685	COG1876	peptidase activity
CP523_RS14690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP523_RS14695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP523_RS14725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP523_RS14755	COG4211	Belongs to the binding-protein-dependent transport system permease family
CP523_RS14760	COG2207	Transcriptional regulator
CP523_RS14760	COG4753	response regulator
CP523_RS14760	COG2207	Transcriptional regulator
CP523_RS14760	COG4753	response regulator
CP523_RS14765	COG2972	Histidine kinase
CP523_RS14785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP523_RS14800	COG1960	acyl-CoA dehydrogenase activity
CP523_RS14805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP523_RS14815	COG1607	acyl-coa hydrolase
CP523_RS14835	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CP523_RS14840	COG0728	peptidoglycan biosynthetic process
CP523_RS14865	COG0012	GTP binding
CP523_RS14875	COG2001	Belongs to the MraZ family
CP523_RS14890	COG0768	penicillin binding
CP523_RS14900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CP523_RS14910	COG0772	Belongs to the SEDS family
CP523_RS14925	COG3856	small basic protein
CP523_RS14935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CP523_RS14940	COG1799	cell septum assembly
CP523_RS14950	COG2302	S4 RNA-binding domain
CP523_RS14955	COG3599	regulation of cell shape
CP523_RS14960	COG0564	pseudouridine synthase activity
CP523_RS14970	COG0116	Belongs to the methyltransferase superfamily
CP523_RS14985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CP523_RS15030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP523_RS15040	COG3854	ATPases associated with a variety of cellular activities
CP523_RS15080	COG1302	Protein conserved in bacteria
CP523_RS15095	COG1570	exodeoxyribonuclease VII activity
CP523_RS15105	COG0142	geranyltranstransferase activity
CP523_RS15110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP523_RS15115	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CP523_RS15120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP523_RS15130	COG0497	DNA recombination
CP523_RS15135	COG0750	zinc metalloprotease
CP523_RS15155	COG0745	RESPONSE REGULATOR receiver
CP523_RS15165	COG0494	nUDIX hydrolase
CP523_RS15175	COG4974	Belongs to the 'phage' integrase family
CP523_RS15180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CP523_RS15190	COG1686	Belongs to the peptidase S11 family
CP523_RS15210	COG3874	Sporulation protein YtfJ
CP523_RS15220	COG1686	Belongs to the peptidase S11 family
CP523_RS15230	COG0445	tRNA wobble uridine modification
CP523_RS15290	COG2052	Domain of unknown function (DUF370)
CP523_RS15310	COG5484	DNA packaging
CP523_RS15445	COG3546	catalase activity
CP523_RS15470	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CP523_RS15485	COG3328	transposase activity
CP523_RS15500	COG0110	maltose O-acetyltransferase activity
CP523_RS15515	COG1309	transcriptional regulator
CP523_RS15520	COG0038	chloride channel
CP523_RS15555	COG1725	Transcriptional regulator
CP523_RS15560	COG1131	(ABC) transporter
CP523_RS15590	COG3481	metal-dependent phosphohydrolase, HD sub domain
CP523_RS15640	COG0243	molybdopterin cofactor binding
CP523_RS15650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP523_RS15660	COG1492	cobalamin metabolic process
CP523_RS15675	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP523_RS15685	COG4149	molybdate abc transporter
CP523_RS15690	COG1058	Belongs to the CinA family
CP523_RS15690	COG1546	Belongs to the CinA family
CP523_RS15695	COG0315	cyclic pyranopterin monophosphate synthase activity
CP523_RS15715	COG1131	(ABC) transporter
CP523_RS15735	COG4086	secreted protein
CP523_RS15770	COG0531	amino acid
CP523_RS15800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay