locus-tag	class	description
CLO1100_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLO1100_RS00010	COG0592	DNA-directed DNA polymerase activity
CLO1100_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLO1100_RS00030	COG0187	DNA topoisomerase II activity
CLO1100_RS00035	COG1192	Involved in chromosome partitioning
CLO1100_RS00040	COG1475	DNA binding
CLO1100_RS00065	COG1183	phosphatidylcholine synthase activity
CLO1100_RS00070	COG0546	phosphoglycolate phosphatase activity
CLO1100_RS00090	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLO1100_RS00090	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLO1100_RS00090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLO1100_RS00090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CLO1100_RS00105	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CLO1100_RS00125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLO1100_RS00130	COG1802	Transcriptional regulator
CLO1100_RS00135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLO1100_RS00165	COG0736	holo-[acyl-carrier-protein] synthase activity
CLO1100_RS00170	COG0420	3'-5' exonuclease activity
CLO1100_RS00175	COG4717	serine-type aminopeptidase activity
CLO1100_RS00180	COG0791	NLP P60 protein
CLO1100_RS00185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLO1100_RS00195	COG2959	enzyme of heme biosynthesis
CLO1100_RS00200	COG1846	Transcriptional regulator
CLO1100_RS00210	COG0242	peptide deformylase activity
CLO1100_RS00215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLO1100_RS00240	COG0004	ammonium transporteR
CLO1100_RS00250	COG4166	transmembrane transport
CLO1100_RS00255	COG4608	Belongs to the ABC transporter superfamily
CLO1100_RS00260	COG0444	Belongs to the ABC transporter superfamily
CLO1100_RS00265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLO1100_RS00270	COG0601	transmembrane transport
CLO1100_RS00275	COG0840	transmembrane signaling receptor activity
CLO1100_RS00285	COG1597	lipid kinase activity
CLO1100_RS00295	COG0419	ATPase involved in DNA repair
CLO1100_RS00300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLO1100_RS00305	COG4213	ABC transporter substrate-binding protein
CLO1100_RS00325	COG0360	Binds together with S18 to 16S ribosomal RNA
CLO1100_RS00330	COG0629	single-stranded DNA binding
CLO1100_RS00335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLO1100_RS00360	COG0077	Prephenate dehydratase
CLO1100_RS00360	COG1605	Chorismate mutase
CLO1100_RS00370	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CLO1100_RS00375	COG0359	binds to the 23S rRNA
CLO1100_RS00380	COG0305	Participates in initiation and elongation during chromosome replication
CLO1100_RS00385	COG0037	tRNA processing
CLO1100_RS00390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CLO1100_RS00395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLO1100_RS00405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLO1100_RS00415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLO1100_RS00420	COG1040	competence protein
CLO1100_RS00440	COG4786	Flagellar basal body rod
CLO1100_RS00440	COG1256	bacterial-type flagellum assembly
CLO1100_RS00450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLO1100_RS00460	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CLO1100_RS00465	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLO1100_RS00470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLO1100_RS00490	COG1516	flagellar protein fliS
CLO1100_RS00555	COG1846	Transcriptional regulator
CLO1100_RS00565	COG0535	radical SAM domain protein
CLO1100_RS00570	COG0488	(ABC) transporter
CLO1100_RS00580	COG2207	Transcriptional regulator
CLO1100_RS00585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLO1100_RS00590	COG0066	3-isopropylmalate dehydratase activity
CLO1100_RS00595	COG0473	3-isopropylmalate dehydrogenase activity
CLO1100_RS00600	COG1335	isochorismatase
CLO1100_RS00610	COG1876	peptidase activity
CLO1100_RS00620	COG4242	Belongs to the peptidase S51 family
CLO1100_RS00645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CLO1100_RS00655	COG0281	malic enzyme
CLO1100_RS00660	COG0246	Mannitol dehydrogenase
CLO1100_RS00665	COG1312	Catalyzes the dehydration of D-mannonate
CLO1100_RS00675	COG0312	modulator of DNA gyrase
CLO1100_RS00685	COG2207	Transcriptional regulator
CLO1100_RS00685	COG0662	Cupin 2, conserved barrel domain protein
CLO1100_RS00690	COG4209	transmembrane transport
CLO1100_RS00695	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS00700	COG1653	transport
CLO1100_RS00705	COG2972	Histidine kinase
CLO1100_RS00710	COG4753	response regulator
CLO1100_RS00710	COG2207	Transcriptional regulator
CLO1100_RS00735	COG4753	response regulator
CLO1100_RS00735	COG2207	Transcriptional regulator
CLO1100_RS00740	COG2972	Histidine kinase
CLO1100_RS00745	COG4753	response regulator
CLO1100_RS00745	COG2207	Transcriptional regulator
CLO1100_RS00755	COG4209	transmembrane transport
CLO1100_RS00760	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS00775	COG1982	Orn Lys Arg decarboxylase major
CLO1100_RS00780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLO1100_RS00785	COG3870	Protein conserved in bacteria
CLO1100_RS00795	COG0470	DNA polymerase III
CLO1100_RS00800	COG1774	PSP1 C-terminal conserved region
CLO1100_RS00810	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CLO1100_RS00815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLO1100_RS00820	COG2002	toxin-antitoxin pair type II binding
CLO1100_RS00825	COG2715	membrane protein required for spore maturation
CLO1100_RS00830	COG0700	Nucleoside recognition
CLO1100_RS00840	COG0084	hydrolase, TatD family'
CLO1100_RS00850	COG3583	domain protein
CLO1100_RS00850	COG3584	3D domain protein
CLO1100_RS00855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLO1100_RS00870	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CLO1100_RS00875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLO1100_RS00880	COG0826	peptidase U32
CLO1100_RS00890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLO1100_RS00900	COG1739	Uncharacterized protein family UPF0029
CLO1100_RS00905	COG0217	transcriptional regulatory protein
CLO1100_RS00915	COG2207	Transcriptional regulator
CLO1100_RS00915	COG3708	Transcriptional regulator
CLO1100_RS00920	COG3708	Transcriptional regulator
CLO1100_RS00920	COG2207	Transcriptional regulator
CLO1100_RS00975	COG1132	(ABC) transporter
CLO1100_RS00990	COG5278	phosphoserine phosphatase activity
CLO1100_RS00990	COG0840	transmembrane signaling receptor activity
CLO1100_RS01000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLO1100_RS01005	COG1131	(ABC) transporter
CLO1100_RS01020	COG2207	Transcriptional regulator
CLO1100_RS01025	COG2972	Histidine kinase
CLO1100_RS01035	COG1175	transmembrane transport
CLO1100_RS01040	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS01045	COG1472	Belongs to the glycosyl hydrolase 3 family
CLO1100_RS01055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLO1100_RS01055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLO1100_RS01060	COG2252	PERMEase
CLO1100_RS01065	COG3458	cephalosporin-C deacetylase activity
CLO1100_RS01075	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CLO1100_RS01080	COG1846	Transcriptional regulator
CLO1100_RS01085	COG0003	Pfam Anion-transporting ATPase
CLO1100_RS01095	COG0003	Pfam Anion-transporting ATPase
CLO1100_RS01105	COG1904	glucuronate isomerase
CLO1100_RS01110	COG1331	Highly conserved protein containing a thioredoxin domain
CLO1100_RS01125	COG0778	Nitroreductase
CLO1100_RS01150	COG2813	Specifically methylates the guanine in position
CLO1100_RS01155	COG0126	phosphoglycerate kinase activity
CLO1100_RS01170	COG0563	adenylate kinase activity
CLO1100_RS01175	COG1725	Transcriptional regulator
CLO1100_RS01180	COG1131	(ABC) transporter
CLO1100_RS01195	COG0004	ammonium transporteR
CLO1100_RS01220	COG1472	Belongs to the glycosyl hydrolase 3 family
CLO1100_RS01225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLO1100_RS01235	COG4733	cellulase activity
CLO1100_RS01240	COG0412	Dienelactone hydrolase
CLO1100_RS01250	COG2217	Heavy metal translocating P-type atpase
CLO1100_RS01285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLO1100_RS01290	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLO1100_RS01295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLO1100_RS01300	COG0840	transmembrane signaling receptor activity
CLO1100_RS01305	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS01310	COG5002	protein histidine kinase activity
CLO1100_RS01335	COG1253	flavin adenine dinucleotide binding
CLO1100_RS01350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLO1100_RS01355	COG0428	transporter
CLO1100_RS01360	COG0009	L-threonylcarbamoyladenylate synthase
CLO1100_RS01365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLO1100_RS01370	COG0698	ribose 5-phosphate isomerase
CLO1100_RS01375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLO1100_RS01380	COG2131	deaminase
CLO1100_RS01385	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLO1100_RS01405	COG0356	it plays a direct role in the translocation of protons across the membrane
CLO1100_RS01410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLO1100_RS01415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLO1100_RS01420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLO1100_RS01425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLO1100_RS01430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLO1100_RS01435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLO1100_RS01440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLO1100_RS01495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLO1100_RS01500	COG2385	sporulation resulting in formation of a cellular spore
CLO1100_RS01510	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLO1100_RS01520	COG0018	arginyl-trna synthetase
CLO1100_RS01530	COG3290	protein histidine kinase activity
CLO1100_RS01530	COG0840	transmembrane signaling receptor activity
CLO1100_RS01545	COG3409	Peptidoglycan-binding domain 1 protein
CLO1100_RS01545	COG0793	Belongs to the peptidase S41A family
CLO1100_RS01550	COG0504	CTP synthase activity
CLO1100_RS01565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLO1100_RS01570	COG1131	(ABC) transporter
CLO1100_RS01590	COG3949	Membrane
CLO1100_RS01605	COG0129	dihydroxy-acid dehydratase activity
CLO1100_RS01610	COG0028	Belongs to the TPP enzyme family
CLO1100_RS01615	COG0513	Belongs to the DEAD box helicase family
CLO1100_RS01620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLO1100_RS01625	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLO1100_RS01630	COG0250	Participates in transcription elongation, termination and antitermination
CLO1100_RS01635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLO1100_RS01640	COG0081	regulation of translation
CLO1100_RS01645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLO1100_RS01655	COG0085	RNA polymerase activity
CLO1100_RS01660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLO1100_RS01665	COG1358	cellular component organization or biogenesis
CLO1100_RS01670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLO1100_RS01675	COG0049	tRNA binding
CLO1100_RS01680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLO1100_RS01685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLO1100_RS01690	COG2972	Histidine kinase
CLO1100_RS01695	COG2207	Transcriptional regulator
CLO1100_RS01695	COG4753	response regulator
CLO1100_RS01705	COG1175	transmembrane transport
CLO1100_RS01745	COG3880	PFAM UvrB UvrC protein
CLO1100_RS01755	COG0542	response to heat
CLO1100_RS01780	COG1215	transferase activity, transferring glycosyl groups
CLO1100_RS01790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLO1100_RS01795	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CLO1100_RS01805	COG1329	Transcriptional regulator
CLO1100_RS01810	COG4956	integral membrane protein (PIN domain superfamily)
CLO1100_RS01815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLO1100_RS01820	COG1132	(ABC) transporter
CLO1100_RS01830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLO1100_RS01835	COG2340	Cysteine-rich secretory protein family
CLO1100_RS01840	COG0564	pseudouridine synthase activity
CLO1100_RS01845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLO1100_RS01870	COG2183	response to ionizing radiation
CLO1100_RS01900	COG0492	ferredoxin-NADP+ reductase activity
CLO1100_RS01905	COG4191	Histidine kinase
CLO1100_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLO1100_RS01920	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CLO1100_RS01930	COG1793	dna ligase
CLO1100_RS01930	COG3285	dna ligase
CLO1100_RS01935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLO1100_RS01950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLO1100_RS01955	COG1368	sulfuric ester hydrolase activity
CLO1100_RS01960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLO1100_RS01965	COG0210	DNA helicase
CLO1100_RS01970	COG2723	6-phospho-beta-galactosidase activity
CLO1100_RS02000	COG0124	histidyl-tRNA synthetase
CLO1100_RS02005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLO1100_RS02010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLO1100_RS02015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLO1100_RS02020	COG0131	Imidazoleglycerol-phosphate dehydratase
CLO1100_RS02030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLO1100_RS02035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLO1100_RS02040	COG0107	imidazoleglycerol-phosphate synthase activity
CLO1100_RS02055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLO1100_RS02060	COG0459	protein refolding
CLO1100_RS02070	COG0516	GMP reductase activity
CLO1100_RS02075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLO1100_RS02080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLO1100_RS02090	COG1366	Belongs to the anti-sigma-factor antagonist family
CLO1100_RS02100	COG1191	sigma factor activity
CLO1100_RS02130	COG0051	transcription antitermination factor activity, RNA binding
CLO1100_RS02135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLO1100_RS02140	COG0088	Forms part of the polypeptide exit tunnel
CLO1100_RS02145	COG0089	rRNA binding
CLO1100_RS02150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLO1100_RS02155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLO1100_RS02160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLO1100_RS02165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLO1100_RS02170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLO1100_RS02175	COG0255	Belongs to the universal ribosomal protein uL29 family
CLO1100_RS02180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLO1100_RS02185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLO1100_RS02190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLO1100_RS02195	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLO1100_RS02200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLO1100_RS02205	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLO1100_RS02210	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLO1100_RS02215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLO1100_RS02220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLO1100_RS02225	COG1841	ribosomal large subunit assembly
CLO1100_RS02230	COG0200	Binds to the 23S rRNA
CLO1100_RS02235	COG0201	protein transport
CLO1100_RS02240	COG0563	adenylate kinase activity
CLO1100_RS02255	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLO1100_RS02260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLO1100_RS02265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLO1100_RS02275	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLO1100_RS02280	COG0202	RNA polymerase activity
CLO1100_RS02285	COG0203	ribosomal protein L17
CLO1100_RS02295	COG2813	Specifically methylates the guanine in position
CLO1100_RS02300	COG1122	ATPase activity
CLO1100_RS02305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLO1100_RS02310	COG0101	tRNA pseudouridine synthase activity
CLO1100_RS02315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLO1100_RS02320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLO1100_RS02325	COG1914	H( )-stimulated, divalent metal cation uptake system
CLO1100_RS02345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS02345	COG4221	oxidoreductase activity
CLO1100_RS02345	COG0300	oxidoreductase activity
CLO1100_RS02345	COG3321	synthase
CLO1100_RS02355	COG3321	synthase
CLO1100_RS02355	COG4221	oxidoreductase activity
CLO1100_RS02355	COG0300	oxidoreductase activity
CLO1100_RS02355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS02370	COG1131	(ABC) transporter
CLO1100_RS02385	COG1032	radical SAM domain protein
CLO1100_RS02395	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CLO1100_RS02415	COG1228	amidohydrolase
CLO1100_RS02425	COG1214	PFAM Peptidase M22, glycoprotease
CLO1100_RS02430	COG0456	acetyltransferase
CLO1100_RS02435	COG1067	ATP-dependent peptidase activity
CLO1100_RS02440	COG1595	DNA-templated transcription, initiation
CLO1100_RS02460	COG0322	excinuclease ABC activity
CLO1100_RS02470	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLO1100_RS02475	COG0740	serine-type endopeptidase activity
CLO1100_RS02480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLO1100_RS02485	COG1067	ATP-dependent peptidase activity
CLO1100_RS02485	COG0470	DNA polymerase III
CLO1100_RS02490	COG0577	efflux transmembrane transporter activity
CLO1100_RS02495	COG1136	(ABC) transporter
CLO1100_RS02500	COG5002	protein histidine kinase activity
CLO1100_RS02505	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS02510	COG1525	nuclease
CLO1100_RS02520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLO1100_RS02525	COG0741	lytic transglycosylase activity
CLO1100_RS02540	COG0613	PHP domain protein
CLO1100_RS02545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLO1100_RS02600	COG1396	sequence-specific DNA binding
CLO1100_RS02620	COG1396	sequence-specific DNA binding
CLO1100_RS02625	COG2002	toxin-antitoxin pair type II binding
CLO1100_RS02650	COG0582	viral genome integration into host DNA
CLO1100_RS02750	COG3409	Peptidoglycan-binding domain 1 protein
CLO1100_RS02775	COG1595	DNA-templated transcription, initiation
CLO1100_RS02795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLO1100_RS02800	COG5520	Belongs to the glycosyl hydrolase 30 family
CLO1100_RS02815	COG2273	Hydrolase Family 16
CLO1100_RS02815	COG5297	Belongs to the glycosyl hydrolase family 6
CLO1100_RS02825	COG1032	radical SAM domain protein
CLO1100_RS02830	COG1279	arginine transmembrane transporter activity
CLO1100_RS02855	COG4555	ABC transporter
CLO1100_RS02870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLO1100_RS02875	COG0367	asparagine synthase
CLO1100_RS02895	COG1012	belongs to the aldehyde dehydrogenase family
CLO1100_RS02910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS02920	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLO1100_RS02935	COG0514	ATP-dependent DNA helicase (RecQ)
CLO1100_RS02965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLO1100_RS02970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLO1100_RS02975	COG0251	oxidation-reduction process
CLO1100_RS02990	COG1376	ErfK ybiS ycfS ynhG family protein
CLO1100_RS02995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLO1100_RS03000	COG0765	amino acid transport
CLO1100_RS03005	COG1126	abc transporter atp-binding protein
CLO1100_RS03010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLO1100_RS03015	COG0501	Belongs to the peptidase M48B family
CLO1100_RS03035	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLO1100_RS03050	COG3459	Glycosyltransferase 36 associated
CLO1100_RS03055	COG0538	isocitrate dehydrogenase activity
CLO1100_RS03060	COG2502	aspartate--ammonia ligase
CLO1100_RS03065	COG0017	Asparaginyl-tRNA synthetase
CLO1100_RS03075	COG0653	protein targeting
CLO1100_RS03080	COG0372	Belongs to the citrate synthase family
CLO1100_RS03085	COG0733	neurotransmitter:sodium symporter activity
CLO1100_RS03095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLO1100_RS03115	COG4862	establishment of competence for transformation
CLO1100_RS03120	COG0424	maF-like protein
CLO1100_RS03125	COG2003	Belongs to the UPF0758 family
CLO1100_RS03130	COG1077	Cell shape determining protein MreB Mrl
CLO1100_RS03145	COG0768	penicillin binding
CLO1100_RS03150	COG0850	regulation of cytokinetic process
CLO1100_RS03155	COG2894	cell division
CLO1100_RS03160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLO1100_RS03175	COG1994	Peptidase M50
CLO1100_RS03185	COG0493	'glutamate synthase
CLO1100_RS03205	COG1408	metallophosphoesterase
CLO1100_RS03210	COG0628	permease
CLO1100_RS03220	COG0730	response to heat
CLO1100_RS03230	COG0714	Associated with various cellular activities
CLO1100_RS03250	COG0019	diaminopimelate decarboxylase activity
CLO1100_RS03270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS03290	COG2814	Major facilitator Superfamily
CLO1100_RS03305	COG0840	transmembrane signaling receptor activity
CLO1100_RS03325	COG4555	ABC transporter
CLO1100_RS03340	COG0737	Belongs to the 5'-nucleotidase family
CLO1100_RS03345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS03355	COG0318	PFAM AMP-dependent synthetase and ligase
CLO1100_RS03415	COG2203	Gaf domain
CLO1100_RS03415	COG2199	diguanylate cyclase activity
CLO1100_RS03425	COG0656	L-ascorbic acid biosynthetic process
CLO1100_RS03440	COG1924	4 iron, 4 sulfur cluster binding
CLO1100_RS03455	COG0733	neurotransmitter:sodium symporter activity
CLO1100_RS03460	COG2267	carboxylic ester hydrolase activity
CLO1100_RS03520	COG0371	Dehydrogenase
CLO1100_RS03525	COG0039	L-malate dehydrogenase activity
CLO1100_RS03530	COG3706	GGDEF domain
CLO1100_RS03535	COG2703	oxygen carrier activity
CLO1100_RS03540	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLO1100_RS03545	COG2814	Major facilitator Superfamily
CLO1100_RS03550	COG0546	phosphoglycolate phosphatase activity
CLO1100_RS03560	COG3326	Membrane
CLO1100_RS03565	COG1716	ATPase activity
CLO1100_RS03575	COG0768	penicillin binding
CLO1100_RS03580	COG0646	methionine synthase
CLO1100_RS03580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLO1100_RS03590	COG1022	Amp-dependent synthetase and ligase
CLO1100_RS03600	COG0641	radical SAM
CLO1100_RS03615	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS03620	COG2205	protein histidine kinase activity
CLO1100_RS03620	COG2202	Pas domain
CLO1100_RS03625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLO1100_RS03650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLO1100_RS03665	COG0681	Belongs to the peptidase S26 family
CLO1100_RS03695	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS03700	COG4209	transmembrane transport
CLO1100_RS03705	COG1501	Belongs to the glycosyl hydrolase 31 family
CLO1100_RS03710	COG1472	Belongs to the glycosyl hydrolase 3 family
CLO1100_RS03715	COG2972	Histidine kinase
CLO1100_RS03720	COG2207	Transcriptional regulator
CLO1100_RS03720	COG4753	response regulator
CLO1100_RS03725	COG1874	Beta-galactosidase
CLO1100_RS03730	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CLO1100_RS03740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLO1100_RS03740	COG0723	plastoquinol--plastocyanin reductase activity
CLO1100_RS03745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLO1100_RS03750	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLO1100_RS03760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLO1100_RS03765	COG0347	Belongs to the P(II) protein family
CLO1100_RS03775	COG0004	ammonium transporteR
CLO1100_RS03780	COG2076	Multidrug Resistance protein
CLO1100_RS03785	COG0475	glutathione-regulated potassium exporter activity
CLO1100_RS03790	COG1116	anion transmembrane transporter activity
CLO1100_RS03805	COG0367	asparagine synthase
CLO1100_RS03810	COG0477	Major facilitator Superfamily
CLO1100_RS03825	COG0367	asparagine synthase
CLO1100_RS03840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLO1100_RS03845	COG0154	amidase activity
CLO1100_RS03850	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLO1100_RS03855	COG0067	glutamate synthase
CLO1100_RS03865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLO1100_RS03890	COG0004	ammonium transporteR
CLO1100_RS03895	COG0347	Belongs to the P(II) protein family
CLO1100_RS03900	COG0010	Belongs to the arginase family
CLO1100_RS03910	COG0116	Belongs to the methyltransferase superfamily
CLO1100_RS03910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLO1100_RS03915	COG0564	pseudouridine synthase activity
CLO1100_RS03920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLO1100_RS03925	COG0116	Belongs to the methyltransferase superfamily
CLO1100_RS03930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLO1100_RS03935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLO1100_RS03940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLO1100_RS03945	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS03965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CLO1100_RS03965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CLO1100_RS03975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLO1100_RS04015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLO1100_RS04020	COG0436	Aminotransferase
CLO1100_RS04025	COG1573	uracil-dna glycosylase
CLO1100_RS04030	COG1573	uracil-dna glycosylase
CLO1100_RS04055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLO1100_RS04065	COG1459	type II secretion system
CLO1100_RS04110	COG2133	pyrroloquinoline quinone binding
CLO1100_RS04110	COG5183	chlorophyll binding
CLO1100_RS04120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLO1100_RS04165	COG0824	Thioesterase
CLO1100_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS04185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLO1100_RS04210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLO1100_RS04215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLO1100_RS04220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLO1100_RS04230	COG2223	nitrite transmembrane transporter activity
CLO1100_RS04285	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLO1100_RS04295	COG1960	acyl-CoA dehydrogenase activity
CLO1100_RS04315	COG4221	oxidoreductase activity
CLO1100_RS04315	COG3321	synthase
CLO1100_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS04315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLO1100_RS04360	COG0673	inositol 2-dehydrogenase activity
CLO1100_RS04375	COG0546	phosphoglycolate phosphatase activity
CLO1100_RS04395	COG1879	ABC-type sugar transport system periplasmic component
CLO1100_RS04400	COG1129	ABC transporter
CLO1100_RS04405	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS04410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS04415	COG2972	Histidine kinase
CLO1100_RS04420	COG2207	Transcriptional regulator
CLO1100_RS04420	COG4753	response regulator
CLO1100_RS04425	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS04430	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04435	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04435	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS04435	COG2382	esterase
CLO1100_RS04440	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04445	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS04445	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04445	COG2382	esterase
CLO1100_RS04450	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04455	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS04460	COG3345	alpha-galactosidase
CLO1100_RS04465	COG3250	beta-galactosidase activity
CLO1100_RS04470	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS04470	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04470	COG2382	esterase
CLO1100_RS04475	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04480	COG5520	Belongs to the glycosyl hydrolase 30 family
CLO1100_RS04485	COG2382	esterase
CLO1100_RS04485	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04485	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS04505	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS04510	COG4677	pectinesterase activity
CLO1100_RS04515	COG3401	FG-GAP repeat protein
CLO1100_RS04530	COG2801	Transposase and inactivated derivatives
CLO1100_RS04540	COG4733	cellulase activity
CLO1100_RS04545	COG2972	Histidine kinase
CLO1100_RS04550	COG4753	response regulator
CLO1100_RS04550	COG2207	Transcriptional regulator
CLO1100_RS04560	COG4209	transmembrane transport
CLO1100_RS04565	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS04570	COG3534	alpha-L-arabinofuranosidase
CLO1100_RS04580	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS04605	COG0310	cobalt ion transport
CLO1100_RS04620	COG1122	ATPase activity
CLO1100_RS04625	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CLO1100_RS04675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLO1100_RS04690	COG1797	cobyrinic acid a,c-diamide synthase activity
CLO1100_RS04695	COG1492	cobalamin metabolic process
CLO1100_RS04710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLO1100_RS04720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CLO1100_RS04775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLO1100_RS04785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLO1100_RS04815	COG0463	Glycosyl transferase, family 2
CLO1100_RS04825	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLO1100_RS04830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLO1100_RS04835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLO1100_RS04840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CLO1100_RS04845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLO1100_RS04850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLO1100_RS04870	COG1136	(ABC) transporter
CLO1100_RS04870	COG0577	efflux transmembrane transporter activity
CLO1100_RS04890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLO1100_RS04900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLO1100_RS04905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLO1100_RS04910	COG1534	Rna-binding protein
CLO1100_RS04925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLO1100_RS04930	COG0302	gtp cyclohydrolase
CLO1100_RS04935	COG1418	mRNA catabolic process
CLO1100_RS04940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLO1100_RS04945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLO1100_RS04945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLO1100_RS04950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLO1100_RS04955	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CLO1100_RS04960	COG0297	glycogen (starch) synthase activity
CLO1100_RS05010	COG0165	Argininosuccinate lyase
CLO1100_RS05015	COG0137	argininosuccinate synthase activity
CLO1100_RS05020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLO1100_RS05025	COG0632	four-way junction helicase activity
CLO1100_RS05030	COG2255	four-way junction helicase activity
CLO1100_RS05035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLO1100_RS05040	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLO1100_RS05045	COG5401	PFAM Sporulation and spore germination
CLO1100_RS05050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLO1100_RS05055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLO1100_RS05085	COG3773	Cell wall hydrolase
CLO1100_RS05115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLO1100_RS05120	COG1713	HD superfamily hydrolase involved in NAD metabolism
CLO1100_RS05130	COG0799	negative regulation of ribosome biogenesis
CLO1100_RS05135	COG0488	(ABC) transporter
CLO1100_RS05150	COG1686	Belongs to the peptidase S11 family
CLO1100_RS05155	COG1555	photosystem II stabilization
CLO1100_RS05155	COG1596	polysaccharide export
CLO1100_RS05160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLO1100_RS05190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLO1100_RS05195	COG1956	GAF domain-containing protein
CLO1100_RS05215	COG2268	Band 7 protein
CLO1100_RS05220	COG0840	transmembrane signaling receptor activity
CLO1100_RS05225	COG0488	(ABC) transporter
CLO1100_RS05230	COG2207	Transcriptional regulator
CLO1100_RS05230	COG4753	response regulator
CLO1100_RS05235	COG2972	Histidine kinase
CLO1100_RS05240	COG2373	Large extracellular alpha-helical protein
CLO1100_RS05250	COG1175	transmembrane transport
CLO1100_RS05255	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS05260	COG1554	hydrolase, family 65, central catalytic
CLO1100_RS05265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLO1100_RS05280	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CLO1100_RS05285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLO1100_RS05290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLO1100_RS05300	COG1132	(ABC) transporter
CLO1100_RS05305	COG1132	(ABC) transporter
CLO1100_RS05320	COG0347	Belongs to the P(II) protein family
CLO1100_RS05335	COG1803	Methylglyoxal synthase
CLO1100_RS05350	COG1136	(ABC) transporter
CLO1100_RS05355	COG0577	efflux transmembrane transporter activity
CLO1100_RS05355	COG1136	(ABC) transporter
CLO1100_RS05375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLO1100_RS05390	COG0187	DNA topoisomerase II activity
CLO1100_RS05395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLO1100_RS05405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLO1100_RS05420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLO1100_RS05425	COG1744	ABC transporter substrate-binding protein PnrA-like
CLO1100_RS05430	COG3845	ABC transporter
CLO1100_RS05435	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS05440	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS05450	COG1971	Probably functions as a manganese efflux pump
CLO1100_RS05455	COG0556	nucleotide-excision repair
CLO1100_RS05465	COG1346	cytolysis
CLO1100_RS05475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLO1100_RS05520	COG4974	Belongs to the 'phage' integrase family
CLO1100_RS05525	COG1396	sequence-specific DNA binding
CLO1100_RS05535	COG2002	toxin-antitoxin pair type II binding
CLO1100_RS05795	COG0477	Major facilitator Superfamily
CLO1100_RS05800	COG2314	TM2 domain
CLO1100_RS05815	COG1151	hydroxylamine reductase activity
CLO1100_RS05825	COG2340	Cysteine-rich secretory protein family
CLO1100_RS05840	COG1132	(ABC) transporter
CLO1100_RS05845	COG1132	(ABC) transporter
CLO1100_RS05865	COG1193	negative regulation of DNA recombination
CLO1100_RS05880	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLO1100_RS05885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLO1100_RS05895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLO1100_RS05900	COG1609	Transcriptional regulator
CLO1100_RS05905	COG3459	Glycosyltransferase 36 associated
CLO1100_RS05930	COG0072	phenylalanine-tRNA ligase activity
CLO1100_RS05940	COG0166	Belongs to the GPI family
CLO1100_RS05950	COG0285	dihydrofolate synthase activity
CLO1100_RS05960	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLO1100_RS05970	COG4492	Belongs to the UPF0735 family
CLO1100_RS05975	COG0460	homoserine dehydrogenase
CLO1100_RS05990	COG4496	protein, YerC YecD
CLO1100_RS06000	COG0653	protein targeting
CLO1100_RS06040	COG0484	heat shock protein binding
CLO1100_RS06060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLO1100_RS06065	COG1193	negative regulation of DNA recombination
CLO1100_RS06070	COG1217	gtp-binding protein TYPA
CLO1100_RS06075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLO1100_RS06080	COG4122	O-methyltransferase activity
CLO1100_RS06085	COG0826	peptidase U32
CLO1100_RS06115	COG1518	maintenance of DNA repeat elements
CLO1100_RS06120	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLO1100_RS06130	COG0768	penicillin binding
CLO1100_RS06155	COG5297	Belongs to the glycosyl hydrolase family 6
CLO1100_RS06155	COG4447	cellulose binding
CLO1100_RS06185	COG0464	growth
CLO1100_RS06290	COG1376	ErfK ybiS ycfS ynhG family protein
CLO1100_RS06390	COG1073	alpha beta
CLO1100_RS06395	COG0662	Cupin 2, conserved barrel domain protein
CLO1100_RS06395	COG2207	Transcriptional regulator
CLO1100_RS06400	COG4124	Belongs to the glycosyl hydrolase 26 family
CLO1100_RS06400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS06455	COG3401	FG-GAP repeat protein
CLO1100_RS06485	COG2207	Transcriptional regulator
CLO1100_RS06485	COG3708	Transcriptional regulator
CLO1100_RS06500	COG3546	catalase activity
CLO1100_RS06565	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS06600	COG1192	Involved in chromosome partitioning
CLO1100_RS06605	COG1475	DNA binding
CLO1100_RS06755	COG2373	Large extracellular alpha-helical protein
CLO1100_RS06765	COG2002	toxin-antitoxin pair type II binding
CLO1100_RS06810	COG3209	COG3209 Rhs family protein
CLO1100_RS06860	COG3546	catalase activity
CLO1100_RS06895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLO1100_RS06930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLO1100_RS06940	COG0534	Mate efflux family protein
CLO1100_RS06945	COG0052	Belongs to the universal ribosomal protein uS2 family
CLO1100_RS06950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLO1100_RS06955	COG0528	UMP kinase activity
CLO1100_RS06960	COG0233	cytoplasmic translational termination
CLO1100_RS06975	COG4589	Belongs to the CDS family
CLO1100_RS06980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLO1100_RS06985	COG0750	zinc metalloprotease
CLO1100_RS06990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLO1100_RS07000	COG0779	Required for maturation of 30S ribosomal subunits
CLO1100_RS07005	COG0195	Participates in both transcription termination and antitermination
CLO1100_RS07010	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CLO1100_RS07020	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLO1100_RS07025	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLO1100_RS07030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CLO1100_RS07035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLO1100_RS07040	COG0196	riboflavin kinase activity
CLO1100_RS07045	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLO1100_RS07050	COG0298	carbon dioxide binding
CLO1100_RS07055	COG0409	Hydrogenase expression formation protein
CLO1100_RS07060	COG0309	Hydrogenase expression formation protein (HypE)
CLO1100_RS07065	COG1136	(ABC) transporter
CLO1100_RS07080	COG0577	efflux transmembrane transporter activity
CLO1100_RS07085	COG0612	Peptidase, M16
CLO1100_RS07090	COG0612	Peptidase, M16
CLO1100_RS07095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLO1100_RS07100	COG0772	Belongs to the SEDS family
CLO1100_RS07105	COG2001	Belongs to the MraZ family
CLO1100_RS07110	COG0275	rRNA processing
CLO1100_RS07120	COG0768	penicillin binding
CLO1100_RS07125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLO1100_RS07130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLO1100_RS07135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLO1100_RS07140	COG0772	Belongs to the SEDS family
CLO1100_RS07145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLO1100_RS07165	COG1686	Belongs to the peptidase S11 family
CLO1100_RS07170	COG1032	radical SAM domain protein
CLO1100_RS07175	COG2766	serine protein kinase
CLO1100_RS07180	COG2718	Belongs to the UPF0229 family
CLO1100_RS07185	COG2719	SpoVR family
CLO1100_RS07190	COG0326	Molecular chaperone. Has ATPase activity
CLO1100_RS07195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLO1100_RS07205	COG0840	transmembrane signaling receptor activity
CLO1100_RS07215	COG0583	DNA-binding transcription factor activity
CLO1100_RS07220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLO1100_RS07235	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLO1100_RS07295	COG0515	serine threonine protein kinase
CLO1100_RS07295	COG3064	Membrane
CLO1100_RS07295	COG4991	sh3 domain protein
CLO1100_RS07390	COG4667	esterase of the alpha-beta hydrolase superfamily
CLO1100_RS07400	COG0432	Pfam Uncharacterised protein family UPF0047
CLO1100_RS07435	COG0697	spore germination
CLO1100_RS07445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLO1100_RS07455	COG1686	Belongs to the peptidase S11 family
CLO1100_RS07460	COG0697	spore germination
CLO1100_RS07500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLO1100_RS07505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLO1100_RS07510	COG2385	sporulation resulting in formation of a cellular spore
CLO1100_RS07515	COG0527	aspartate kinase activity
CLO1100_RS07520	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLO1100_RS07525	COG0343	queuine tRNA-ribosyltransferase activity
CLO1100_RS07530	COG1862	Preprotein translocase
CLO1100_RS07550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLO1100_RS07555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLO1100_RS07570	COG0358	DNA primase activity
CLO1100_RS07575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLO1100_RS07590	COG2384	SAM-dependent methyltransferase
CLO1100_RS07620	COG0431	NADPH-dependent FMN reductase
CLO1100_RS07625	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLO1100_RS07635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLO1100_RS07660	COG1136	(ABC) transporter
CLO1100_RS07670	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS07675	COG2205	protein histidine kinase activity
CLO1100_RS07675	COG2202	Pas domain
CLO1100_RS07700	COG0006	proline dipeptidase activity
CLO1100_RS07735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLO1100_RS07790	COG1484	DNA-dependent DNA replication
CLO1100_RS07795	COG0582	viral genome integration into host DNA
CLO1100_RS07825	COG0084	hydrolase, TatD family'
CLO1100_RS07865	COG1702	phosphate starvation-inducible protein PhoH
CLO1100_RS07870	COG1480	7TM receptor with intracellular HD hydrolase
CLO1100_RS07875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLO1100_RS07880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLO1100_RS07885	COG0295	cytidine deaminase activity
CLO1100_RS07890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLO1100_RS07895	COG1381	Involved in DNA repair and RecF pathway recombination
CLO1100_RS07900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLO1100_RS07905	COG3274	enterobacterial common antigen metabolic process
CLO1100_RS07920	COG1132	(ABC) transporter
CLO1100_RS07930	COG4224	UPF0291 protein
CLO1100_RS07935	COG0835	chemotaxis
CLO1100_RS07945	COG0012	GTP binding
CLO1100_RS07960	COG0564	pseudouridine synthase activity
CLO1100_RS07965	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CLO1100_RS07975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLO1100_RS07980	COG1799	cell septum assembly
CLO1100_RS07990	COG2302	S4 RNA-binding domain
CLO1100_RS07995	COG3599	regulation of cell shape
CLO1100_RS08015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLO1100_RS08020	COG1418	mRNA catabolic process
CLO1100_RS08025	COG1692	metallophosphoesterase
CLO1100_RS08040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLO1100_RS08045	COG0564	pseudouridine synthase activity
CLO1100_RS08050	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLO1100_RS08055	COG0540	Belongs to the ATCase OTCase family
CLO1100_RS08060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLO1100_RS08065	COG0284	orotidine-5'-phosphate decarboxylase activity
CLO1100_RS08075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLO1100_RS08080	COG0543	2 iron, 2 sulfur cluster binding
CLO1100_RS08085	COG0167	dihydroorotate dehydrogenase activity
CLO1100_RS08090	COG0588	phosphoglycerate mutase activity
CLO1100_RS08105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLO1100_RS08120	COG1533	DNA photolyase activity
CLO1100_RS08135	COG5001	Diguanylate cyclase
CLO1100_RS08135	COG3300	MHYT domain
CLO1100_RS08140	COG1342	Belongs to the UPF0251 family
CLO1100_RS08155	COG0583	DNA-binding transcription factor activity
CLO1100_RS08190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLO1100_RS08260	COG1132	(ABC) transporter
CLO1100_RS08270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLO1100_RS08275	COG1404	Belongs to the peptidase S8 family
CLO1100_RS08280	COG3858	chitin binding
CLO1100_RS08285	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CLO1100_RS08290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLO1100_RS08295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CLO1100_RS08310	COG4733	cellulase activity
CLO1100_RS08325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLO1100_RS08345	COG3290	protein histidine kinase activity
CLO1100_RS08345	COG3829	transcription factor binding
CLO1100_RS08350	COG3033	Beta-eliminating lyase
CLO1100_RS08355	COG1113	amino acid transport
CLO1100_RS08360	COG0251	oxidation-reduction process
CLO1100_RS08365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLO1100_RS08375	COG1247	-acetyltransferase
CLO1100_RS08385	COG0210	DNA helicase
CLO1100_RS08390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CLO1100_RS08395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLO1100_RS08405	COG0586	Pfam SNARE associated Golgi protein
CLO1100_RS08425	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CLO1100_RS08450	COG1546	Belongs to the CinA family
CLO1100_RS08450	COG1058	Belongs to the CinA family
CLO1100_RS08460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLO1100_RS08465	COG2137	regulation of response to DNA damage stimulus
CLO1100_RS08470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLO1100_RS08475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLO1100_RS08480	COG2030	dehydratase
CLO1100_RS08485	COG0416	fatty acid biosynthetic process
CLO1100_RS08490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLO1100_RS08495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLO1100_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS08505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS08510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLO1100_RS08515	COG0571	ribonuclease III activity
CLO1100_RS08525	COG2359	stage V sporulation protein S
CLO1100_RS08530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLO1100_RS08550	COG0667	Aldo Keto reductase
CLO1100_RS08560	COG0552	protein localization to endoplasmic reticulum
CLO1100_RS08565	COG1615	UPF0182 protein
CLO1100_RS08570	COG0531	amino acid
CLO1100_RS08580	COG4443	Transcriptional Coactivator p15 (PC4)
CLO1100_RS08595	COG1368	sulfuric ester hydrolase activity
CLO1100_RS08615	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CLO1100_RS08620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLO1100_RS08625	COG0228	four-way junction DNA binding
CLO1100_RS08630	COG1837	Belongs to the UPF0109 family
CLO1100_RS08635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLO1100_RS08640	COG0336	Belongs to the RNA methyltransferase TrmD family
CLO1100_RS08645	COG1433	Dinitrogenase iron-molybdenum cofactor
CLO1100_RS08645	COG0535	radical SAM domain protein
CLO1100_RS08655	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CLO1100_RS08665	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CLO1100_RS08670	COG0626	cystathionine gamma-synthase activity
CLO1100_RS08675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLO1100_RS08685	COG0335	large ribosomal subunit rRNA binding
CLO1100_RS08700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLO1100_RS08710	COG2257	FlhB HrpN YscU SpaS Family
CLO1100_RS08715	COG0792	nuclease activity
CLO1100_RS08725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLO1100_RS08730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLO1100_RS08735	COG2188	Transcriptional regulator
CLO1100_RS08745	COG0586	Pfam SNARE associated Golgi protein
CLO1100_RS08750	COG1113	amino acid transport
CLO1100_RS08760	COG5297	Belongs to the glycosyl hydrolase family 6
CLO1100_RS08765	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLO1100_RS08770	COG4733	cellulase activity
CLO1100_RS08800	COG4733	cellulase activity
CLO1100_RS08810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS08820	COG0583	DNA-binding transcription factor activity
CLO1100_RS08830	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLO1100_RS08835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLO1100_RS08845	COG2217	Heavy metal translocating P-type atpase
CLO1100_RS08850	COG0791	NLP P60 protein
CLO1100_RS08855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLO1100_RS08865	COG0747	negative chemotaxis
CLO1100_RS08875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLO1100_RS08880	COG0444	Belongs to the ABC transporter superfamily
CLO1100_RS08885	COG4608	Belongs to the ABC transporter superfamily
CLO1100_RS08895	COG1151	hydroxylamine reductase activity
CLO1100_RS08910	COG4124	Belongs to the glycosyl hydrolase 26 family
CLO1100_RS08915	COG4447	cellulose binding
CLO1100_RS08915	COG4733	cellulase activity
CLO1100_RS08920	COG3291	Pkd domain containing protein
CLO1100_RS08925	COG3291	Pkd domain containing protein
CLO1100_RS08945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLO1100_RS08950	COG3621	Patatin-like phospholipase
CLO1100_RS08980	COG1252	NADH dehydrogenase
CLO1100_RS08985	COG1477	protein flavinylation
CLO1100_RS09000	COG0142	geranyltranstransferase activity
CLO1100_RS09005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLO1100_RS09010	COG0242	peptide deformylase activity
CLO1100_RS09015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLO1100_RS09025	COG2738	Putative neutral zinc metallopeptidase
CLO1100_RS09030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLO1100_RS09030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLO1100_RS09035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLO1100_RS09040	COG0631	protein serine/threonine phosphatase activity
CLO1100_RS09045	COG0515	serine threonine protein kinase
CLO1100_RS09045	COG2815	serine threonine protein kinase
CLO1100_RS09050	COG1162	GTPase activity
CLO1100_RS09055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLO1100_RS09125	COG2002	toxin-antitoxin pair type II binding
CLO1100_RS09145	COG4977	sequence-specific DNA binding
CLO1100_RS09160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLO1100_RS09165	COG0348	domain, Protein
CLO1100_RS09165	COG3901	Regulator of nitric oxide reductase transcription
CLO1100_RS09175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLO1100_RS09180	COG4124	Belongs to the glycosyl hydrolase 26 family
CLO1100_RS09185	COG1011	Hydrolase
CLO1100_RS09210	COG3321	synthase
CLO1100_RS09215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLO1100_RS09220	COG0785	Cytochrome C biogenesis protein
CLO1100_RS09225	COG0671	phosphoesterase, PA-phosphatase related
CLO1100_RS09280	COG3848	Pyruvate phosphate dikinase
CLO1100_RS09280	COG0574	Belongs to the PEP-utilizing enzyme family
CLO1100_RS09300	COG3345	alpha-galactosidase
CLO1100_RS09320	COG1461	Dihydroxyacetone kinase
CLO1100_RS09325	COG2376	Dihydroxyacetone kinase
CLO1100_RS09330	COG0698	ribose 5-phosphate isomerase
CLO1100_RS09335	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS09340	COG1879	ABC-type sugar transport system periplasmic component
CLO1100_RS09345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS09350	COG1129	ABC transporter
CLO1100_RS09355	COG4753	response regulator
CLO1100_RS09355	COG2207	Transcriptional regulator
CLO1100_RS09360	COG2972	Histidine kinase
CLO1100_RS09365	COG0861	Integral membrane protein TerC family
CLO1100_RS09370	COG0492	ferredoxin-NADP+ reductase activity
CLO1100_RS09385	COG0175	sulfate reduction
CLO1100_RS09390	COG0175	sulfate reduction
CLO1100_RS09405	COG4208	sulfate ABC transporter
CLO1100_RS09415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLO1100_RS09425	COG4447	cellulose binding
CLO1100_RS09425	COG4733	cellulase activity
CLO1100_RS09435	COG0730	response to heat
CLO1100_RS09450	COG1388	LysM domain
CLO1100_RS09450	COG0791	NLP P60 protein
CLO1100_RS09460	COG4974	Belongs to the 'phage' integrase family
CLO1100_RS09490	COG3290	protein histidine kinase activity
CLO1100_RS09495	COG3279	Response regulator of the LytR AlgR family
CLO1100_RS09510	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CLO1100_RS09525	COG1595	DNA-templated transcription, initiation
CLO1100_RS09535	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CLO1100_RS09570	COG0574	Belongs to the PEP-utilizing enzyme family
CLO1100_RS09570	COG3848	Pyruvate phosphate dikinase
CLO1100_RS09585	COG2207	Transcriptional regulator
CLO1100_RS09585	COG3708	Transcriptional regulator
CLO1100_RS09595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLO1100_RS09610	COG0301	tRNA thio-modification
CLO1100_RS09625	COG3260	NADH ubiquinone oxidoreductase 20
CLO1100_RS09630	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CLO1100_RS09630	COG3261	NADH dehydrogenase
CLO1100_RS09635	COG0651	ATP synthesis coupled electron transport
CLO1100_RS09650	COG0651	ATP synthesis coupled electron transport
CLO1100_RS09655	COG1388	LysM domain
CLO1100_RS09660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLO1100_RS09665	COG1923	regulation of RNA biosynthetic process
CLO1100_RS09670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLO1100_RS09675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLO1100_RS09680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLO1100_RS09690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLO1100_RS09700	COG2050	protein possibly involved in aromatic compounds catabolism
CLO1100_RS09710	COG0740	serine-type endopeptidase activity
CLO1100_RS09715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLO1100_RS09725	COG0612	Peptidase, M16
CLO1100_RS09730	COG1185	polyribonucleotide nucleotidyltransferase activity
CLO1100_RS09735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLO1100_RS09740	COG0714	Associated with various cellular activities
CLO1100_RS09750	COG1305	Transglutaminase-like
CLO1100_RS09780	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLO1100_RS09795	COG2205	protein histidine kinase activity
CLO1100_RS09815	COG1316	TRANSCRIPTIONal
CLO1100_RS09825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLO1100_RS09835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLO1100_RS09840	COG2848	UPF0210 protein
CLO1100_RS09845	COG3830	Belongs to the UPF0237 family
CLO1100_RS09860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLO1100_RS09870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLO1100_RS09875	COG0539	negative regulation of cytoplasmic translation
CLO1100_RS09875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLO1100_RS09880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLO1100_RS09900	COG2081	HI0933 family
CLO1100_RS09920	COG0511	ligase activity, forming carbon-carbon bonds
CLO1100_RS09925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLO1100_RS09930	COG1191	sigma factor activity
CLO1100_RS09935	COG2133	pyrroloquinoline quinone binding
CLO1100_RS09935	COG5183	chlorophyll binding
CLO1100_RS09940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CLO1100_RS09950	COG1187	pseudouridine synthase activity
CLO1100_RS09955	COG3874	Sporulation protein YtfJ
CLO1100_RS09965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLO1100_RS09970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLO1100_RS09975	COG1994	Peptidase M50
CLO1100_RS09980	COG1686	Belongs to the peptidase S11 family
CLO1100_RS09985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CLO1100_RS09990	COG4974	Belongs to the 'phage' integrase family
CLO1100_RS09995	COG1300	Membrane
CLO1100_RS10005	COG0328	RNA-DNA hybrid ribonuclease activity
CLO1100_RS10010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLO1100_RS10020	COG1620	l-lactate permease
CLO1100_RS10030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLO1100_RS10060	COG4608	Belongs to the ABC transporter superfamily
CLO1100_RS10065	COG0444	Belongs to the ABC transporter superfamily
CLO1100_RS10070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLO1100_RS10075	COG0601	transmembrane transport
CLO1100_RS10090	COG1132	(ABC) transporter
CLO1100_RS10095	COG1132	(ABC) transporter
CLO1100_RS10100	COG1323	Belongs to the UPF0348 family
CLO1100_RS10105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLO1100_RS10110	COG0438	transferase activity, transferring glycosyl groups
CLO1100_RS10120	COG1074	ATP-dependent DNA helicase activity
CLO1100_RS10125	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CLO1100_RS10150	COG0517	IMP dehydrogenase activity
CLO1100_RS10155	COG0789	Transcriptional regulator
CLO1100_RS10165	COG0697	spore germination
CLO1100_RS10175	COG0531	amino acid
CLO1100_RS10180	COG1376	ErfK ybiS ycfS ynhG family protein
CLO1100_RS10190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CLO1100_RS10195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLO1100_RS10200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLO1100_RS10210	COG2814	Major facilitator Superfamily
CLO1100_RS10220	COG0423	glycine-tRNA ligase activity
CLO1100_RS10225	COG1758	RNA polymerase activity
CLO1100_RS10230	COG0194	GDP metabolic process
CLO1100_RS10235	COG2052	Domain of unknown function (DUF370)
CLO1100_RS10240	COG1561	YicC-like family, N-terminal region
CLO1100_RS10245	COG2201	protein-glutamate methylesterase activity
CLO1100_RS10250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLO1100_RS10255	COG2264	protein methyltransferase activity
CLO1100_RS10260	COG0484	heat shock protein binding
CLO1100_RS10265	COG0443	Heat shock 70 kDa protein
CLO1100_RS10275	COG1420	regulation of RNA biosynthetic process
CLO1100_RS10290	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CLO1100_RS10295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLO1100_RS10310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLO1100_RS10315	COG1122	ATPase activity
CLO1100_RS10320	COG1122	ATPase activity
CLO1100_RS10330	COG3119	arylsulfatase activity
CLO1100_RS10340	COG4733	cellulase activity
CLO1100_RS10350	COG1216	Glycosyl transferase, family 2
CLO1100_RS10370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLO1100_RS10375	COG0463	Glycosyl transferase, family 2
CLO1100_RS10385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLO1100_RS10445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLO1100_RS10520	COG0582	viral genome integration into host DNA
CLO1100_RS10530	COG0561	phosphatase activity
CLO1100_RS10545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLO1100_RS10550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLO1100_RS10565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLO1100_RS10570	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CLO1100_RS10575	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CLO1100_RS10580	COG0705	Rhomboid family
CLO1100_RS10580	COG0457	Tetratricopeptide repeat
CLO1100_RS10585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLO1100_RS10585	COG0646	methionine synthase
CLO1100_RS10590	COG0318	PFAM AMP-dependent synthetase and ligase
CLO1100_RS10600	COG4585	Histidine kinase
CLO1100_RS10640	COG1592	Rubrerythrin
CLO1100_RS10655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLO1100_RS10660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLO1100_RS10680	COG1104	cysteine desulfurase activity
CLO1100_RS10685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLO1100_RS10690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLO1100_RS10700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLO1100_RS10705	COG3314	Sporulation integral membrane protein YlbJ
CLO1100_RS10715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLO1100_RS10720	COG0742	ribosomal rna small subunit methyltransferase
CLO1100_RS10725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLO1100_RS10730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLO1100_RS10740	COG5001	Diguanylate cyclase
CLO1100_RS10740	COG4251	negative regulation of phosphorylation
CLO1100_RS10740	COG3706	GGDEF domain
CLO1100_RS10740	COG2203	Gaf domain
CLO1100_RS10750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLO1100_RS10755	COG0297	glycogen (starch) synthase activity
CLO1100_RS10765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLO1100_RS10770	COG5002	protein histidine kinase activity
CLO1100_RS10775	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS10780	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS10785	COG0750	zinc metalloprotease
CLO1100_RS10790	COG0497	DNA recombination
CLO1100_RS10795	COG1438	arginine binding
CLO1100_RS10800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLO1100_RS10805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CLO1100_RS10810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLO1100_RS10825	COG1722	exodeoxyribonuclease VII activity
CLO1100_RS10830	COG1570	exodeoxyribonuclease VII activity
CLO1100_RS10835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLO1100_RS10850	COG1302	Protein conserved in bacteria
CLO1100_RS10890	COG3854	ATPases associated with a variety of cellular activities
CLO1100_RS10900	COG1131	(ABC) transporter
CLO1100_RS10905	COG1725	Transcriptional regulator
CLO1100_RS10920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLO1100_RS10925	COG0006	proline dipeptidase activity
CLO1100_RS10930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLO1100_RS10940	COG1362	aminopeptidase activity
CLO1100_RS10945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLO1100_RS10960	COG0482	sulfurtransferase activity
CLO1100_RS10965	COG0822	iron-sulfur transferase activity
CLO1100_RS10975	COG1959	2 iron, 2 sulfur cluster binding
CLO1100_RS10990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLO1100_RS11000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLO1100_RS11010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLO1100_RS11015	COG0481	GTPase activity
CLO1100_RS11045	COG2205	protein histidine kinase activity
CLO1100_RS11055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLO1100_RS11065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLO1100_RS11070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLO1100_RS11075	COG1490	D-aminoacyl-tRNA deacylase activity
CLO1100_RS11080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLO1100_RS11085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLO1100_RS11090	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS11095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLO1100_RS11095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CLO1100_RS11105	COG0658	competence protein
CLO1100_RS11105	COG2333	competence protein COMEC
CLO1100_RS11130	COG1846	Transcriptional regulator
CLO1100_RS11135	COG1511	domain protein
CLO1100_RS11145	COG1522	sequence-specific DNA binding
CLO1100_RS11155	COG0436	Aminotransferase
CLO1100_RS11180	COG0697	spore germination
CLO1100_RS11255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLO1100_RS11270	COG0268	Binds directly to 16S ribosomal RNA
CLO1100_RS11275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLO1100_RS11280	COG0534	Mate efflux family protein
CLO1100_RS11285	COG4753	response regulator
CLO1100_RS11285	COG2207	Transcriptional regulator
CLO1100_RS11290	COG3275	phosphorelay sensor kinase activity
CLO1100_RS11300	COG4214	carbohydrate transport
CLO1100_RS11310	COG4213	ABC transporter substrate-binding protein
CLO1100_RS11320	COG0352	thiamine-phosphate diphosphorylase activity
CLO1100_RS11325	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CLO1100_RS11330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CLO1100_RS11335	COG0351	phosphomethylpyrimidine kinase
CLO1100_RS11335	COG0352	thiamine-phosphate diphosphorylase activity
CLO1100_RS11345	COG0735	belongs to the Fur family
CLO1100_RS11370	COG0492	ferredoxin-NADP+ reductase activity
CLO1100_RS11400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLO1100_RS11405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLO1100_RS11405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLO1100_RS11410	COG0307	riboflavin synthase, alpha
CLO1100_RS11425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLO1100_RS11435	COG2135	peptidase activity
CLO1100_RS11460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS11500	COG1191	sigma factor activity
CLO1100_RS11510	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLO1100_RS11515	COG1776	CheC inhibitor of MCP methylation
CLO1100_RS11520	COG0835	chemotaxis
CLO1100_RS11525	COG0643	Histidine kinase
CLO1100_RS11525	COG2198	Histidine kinase
CLO1100_RS11530	COG2201	protein-glutamate methylesterase activity
CLO1100_RS11540	COG1419	protein localization to endoplasmic reticulum
CLO1100_RS11545	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLO1100_RS11550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLO1100_RS11555	COG1684	flagellar biosynthetic protein fliR
CLO1100_RS11560	COG1987	bacterial-type flagellum assembly
CLO1100_RS11565	COG1338	Plays a role in the flagellum-specific transport system
CLO1100_RS11575	COG2201	protein-glutamate methylesterase activity
CLO1100_RS11580	COG1776	CheC inhibitor of MCP methylation
CLO1100_RS11580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLO1100_RS11585	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLO1100_RS11595	COG1582	Flagellar protein (FlbD)
CLO1100_RS11600	COG1749	Flagellar hook protein flgE
CLO1100_RS11610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CLO1100_RS11630	COG1157	protein secretion by the type III secretion system
CLO1100_RS11640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLO1100_RS11650	COG1677	Flagellar hook-basal body complex protein FliE
CLO1100_RS11655	COG1558	bacterial-type flagellum-dependent cell motility
CLO1100_RS11660	COG1815	bacterial-type flagellum-dependent cell motility
CLO1100_RS11665	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CLO1100_RS11670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLO1100_RS11845	COG0758	DNA mediated transformation
CLO1100_RS11850	COG0606	chelatase, subunit chli
CLO1100_RS11855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLO1100_RS11860	COG1873	PFAM PRC-barrel domain
CLO1100_RS11865	COG1191	sigma factor activity
CLO1100_RS11870	COG1191	sigma factor activity
CLO1100_RS11880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLO1100_RS11890	COG3856	small basic protein
CLO1100_RS11895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLO1100_RS11900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLO1100_RS11905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLO1100_RS11910	COG3442	glutamine amidotransferase
CLO1100_RS11915	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CLO1100_RS11925	COG0741	lytic transglycosylase activity
CLO1100_RS11930	COG0237	dephospho-CoA kinase activity
CLO1100_RS11935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLO1100_RS11935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLO1100_RS11945	COG1595	DNA-templated transcription, initiation
CLO1100_RS11950	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS11955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLO1100_RS11970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLO1100_RS11975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLO1100_RS11985	COG0569	domain protein
CLO1100_RS11990	COG2323	membrane
CLO1100_RS12025	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS12035	COG2954	triphosphatase activity
CLO1100_RS12045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLO1100_RS12050	COG0537	adenosine 5'-monophosphoramidase activity
CLO1100_RS12055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLO1100_RS12065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLO1100_RS12070	COG0835	chemotaxis
CLO1100_RS12085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLO1100_RS12090	COG3290	protein histidine kinase activity
CLO1100_RS12090	COG0840	transmembrane signaling receptor activity
CLO1100_RS12095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLO1100_RS12105	COG0581	inorganic phosphate transmembrane transporter activity
CLO1100_RS12110	COG0573	inorganic phosphate transmembrane transporter activity
CLO1100_RS12115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLO1100_RS12120	COG0704	Plays a role in the regulation of phosphate uptake
CLO1100_RS12125	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS12130	COG5002	protein histidine kinase activity
CLO1100_RS12135	COG3459	Glycosyltransferase 36 associated
CLO1100_RS12140	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS12155	COG2207	Transcriptional regulator
CLO1100_RS12155	COG4753	response regulator
CLO1100_RS12155	COG2207	Transcriptional regulator
CLO1100_RS12155	COG4753	response regulator
CLO1100_RS12160	COG2972	Histidine kinase
CLO1100_RS12165	COG1653	transport
CLO1100_RS12170	COG0542	response to heat
CLO1100_RS12175	COG0306	phosphate transporter
CLO1100_RS12190	COG3859	Proton-coupled thiamine transporter YuaJ
CLO1100_RS12195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLO1100_RS12220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLO1100_RS12225	COG1388	LysM domain
CLO1100_RS12225	COG0791	NLP P60 protein
CLO1100_RS12230	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLO1100_RS12240	COG1160	GTP binding
CLO1100_RS12250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLO1100_RS12260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLO1100_RS12265	COG0280	phosphate acetyltransferase
CLO1100_RS12280	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
CLO1100_RS12305	COG2205	protein histidine kinase activity
CLO1100_RS12310	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS12380	COG1131	(ABC) transporter
CLO1100_RS12385	COG1309	transcriptional regulator
CLO1100_RS12390	COG2755	lipolytic protein G-D-S-L family
CLO1100_RS12390	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS12395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLO1100_RS12410	COG0402	S-adenosylhomocysteine deaminase activity
CLO1100_RS12415	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CLO1100_RS12430	COG1187	pseudouridine synthase activity
CLO1100_RS12435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLO1100_RS12435	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CLO1100_RS12445	COG1595	DNA-templated transcription, initiation
CLO1100_RS12455	COG1802	Transcriptional regulator
CLO1100_RS12460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLO1100_RS12465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLO1100_RS12470	COG0840	transmembrane signaling receptor activity
CLO1100_RS12475	COG0151	Belongs to the GarS family
CLO1100_RS12480	COG0138	bifunctional purine biosynthesis protein purh
CLO1100_RS12485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLO1100_RS12490	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLO1100_RS12495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLO1100_RS12500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLO1100_RS12515	COG3842	ATPase activity
CLO1100_RS12520	COG4149	molybdate abc transporter
CLO1100_RS12525	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLO1100_RS12565	COG0347	Belongs to the P(II) protein family
CLO1100_RS12575	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CLO1100_RS12590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLO1100_RS12610	COG4191	Histidine kinase
CLO1100_RS12615	COG0673	inositol 2-dehydrogenase activity
CLO1100_RS12635	COG1063	alcohol dehydrogenase
CLO1100_RS12645	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS12680	COG1619	proteins homologs of microcin C7 resistance protein MccF
CLO1100_RS12735	COG0519	Catalyzes the synthesis of GMP from XMP
CLO1100_RS12740	COG1242	4 iron, 4 sulfur cluster binding
CLO1100_RS12745	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CLO1100_RS12750	COG1691	(AIR) carboxylase
CLO1100_RS12755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLO1100_RS12760	COG0561	phosphatase activity
CLO1100_RS12765	COG0436	Aminotransferase
CLO1100_RS12770	COG1522	sequence-specific DNA binding
CLO1100_RS12780	COG3118	belongs to the thioredoxin family
CLO1100_RS12790	COG5434	Belongs to the glycosyl hydrolase 28 family
CLO1100_RS12790	COG4632	Exopolysaccharide biosynthesis protein
CLO1100_RS12810	COG1924	4 iron, 4 sulfur cluster binding
CLO1100_RS12825	COG1649	PFAM Uncharacterised BCR, COG1649
CLO1100_RS12845	COG0191	fructose-bisphosphate aldolase activity
CLO1100_RS12850	COG0205	6-phosphofructokinase activity
CLO1100_RS12855	COG3290	protein histidine kinase activity
CLO1100_RS12860	COG1030	water channel activity
CLO1100_RS12865	COG4864	UPF0365 protein
CLO1100_RS12875	COG3279	Response regulator of the LytR AlgR family
CLO1100_RS12885	COG1882	Formate acetyltransferase
CLO1100_RS12905	COG0667	Aldo Keto reductase
CLO1100_RS12945	COG0840	transmembrane signaling receptor activity
CLO1100_RS12950	COG3906	Belongs to the UPF0473 family
CLO1100_RS12955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLO1100_RS12960	COG4472	Bacterial protein of unknown function (DUF965)
CLO1100_RS12965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLO1100_RS12975	COG1215	transferase activity, transferring glycosyl groups
CLO1100_RS12985	COG1683	Conserved Protein
CLO1100_RS12990	COG0557	exoribonuclease II activity
CLO1100_RS13000	COG5002	protein histidine kinase activity
CLO1100_RS13010	COG0726	polysaccharide deacetylase
CLO1100_RS13020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLO1100_RS13025	COG0148	phosphopyruvate hydratase activity
CLO1100_RS13030	COG2207	Transcriptional regulator
CLO1100_RS13030	COG3708	Transcriptional regulator
CLO1100_RS13050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLO1100_RS13055	COG0149	triose-phosphate isomerase activity
CLO1100_RS13055	COG0126	phosphoglycerate kinase activity
CLO1100_RS13095	COG3279	Response regulator of the LytR AlgR family
CLO1100_RS13100	COG0653	protein targeting
CLO1100_RS13105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLO1100_RS13110	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CLO1100_RS13115	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLO1100_RS13135	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLO1100_RS13155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLO1100_RS13175	COG2172	sigma factor antagonist activity
CLO1100_RS13180	COG1366	Belongs to the anti-sigma-factor antagonist family
CLO1100_RS13185	COG1481	regulation of sporulation
CLO1100_RS13195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CLO1100_RS13200	COG1660	Displays ATPase and GTPase activities
CLO1100_RS13205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLO1100_RS13210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLO1100_RS13215	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLO1100_RS13220	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CLO1100_RS13235	COG1811	Na channel or pump
CLO1100_RS13240	COG0617	tRNA 3'-terminal CCA addition
CLO1100_RS13270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CLO1100_RS13315	COG2201	protein-glutamate methylesterase activity
CLO1100_RS13325	COG0840	transmembrane signaling receptor activity
CLO1100_RS13330	COG0835	chemotaxis
CLO1100_RS13335	COG2198	Histidine kinase
CLO1100_RS13335	COG0643	Histidine kinase
CLO1100_RS13340	COG2201	protein-glutamate methylesterase activity
CLO1100_RS13360	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS13365	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS13370	COG5002	protein histidine kinase activity
CLO1100_RS13385	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS13390	COG1819	glycosyl
CLO1100_RS13395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLO1100_RS13400	COG1819	glycosyl
CLO1100_RS13405	COG1819	glycosyl
CLO1100_RS13430	COG3321	synthase
CLO1100_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS13430	COG0300	oxidoreductase activity
CLO1100_RS13430	COG0318	PFAM AMP-dependent synthetase and ligase
CLO1100_RS13430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLO1100_RS13460	COG4447	cellulose binding
CLO1100_RS13460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS13480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLO1100_RS13490	COG1304	FMN binding
CLO1100_RS13505	COG1131	(ABC) transporter
CLO1100_RS13535	COG1136	(ABC) transporter
CLO1100_RS13550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLO1100_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS13575	COG2207	Transcriptional regulator
CLO1100_RS13575	COG3708	Transcriptional regulator
CLO1100_RS13580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLO1100_RS13595	COG2207	Transcriptional regulator
CLO1100_RS13595	COG3708	Transcriptional regulator
CLO1100_RS13600	COG1501	Belongs to the glycosyl hydrolase 31 family
CLO1100_RS13605	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS13610	COG1175	transmembrane transport
CLO1100_RS13625	COG1940	carbohydrate kinase activity
CLO1100_RS13645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLO1100_RS13650	COG0698	ribose 5-phosphate isomerase
CLO1100_RS13655	COG3958	Transketolase
CLO1100_RS13660	COG3959	Transketolase, thiamine diphosphate binding domain
CLO1100_RS13665	COG1454	alcohol dehydrogenase
CLO1100_RS13675	COG2376	Dihydroxyacetone kinase
CLO1100_RS13695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLO1100_RS13705	COG2207	Transcriptional regulator
CLO1100_RS13715	COG4447	cellulose binding
CLO1100_RS13720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLO1100_RS13730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLO1100_RS13745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLO1100_RS13750	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CLO1100_RS13760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLO1100_RS13775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLO1100_RS13795	COG0628	permease
CLO1100_RS13815	COG1132	(ABC) transporter
CLO1100_RS13825	COG1846	Transcriptional regulator
CLO1100_RS13830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLO1100_RS13855	COG1122	ATPase activity
CLO1100_RS13865	COG0310	cobalt ion transport
CLO1100_RS13880	COG1482	cell wall glycoprotein biosynthetic process
CLO1100_RS13885	COG1668	transmembrane transport
CLO1100_RS13890	COG4152	abc transporter atp-binding protein
CLO1100_RS13910	COG2801	Transposase and inactivated derivatives
CLO1100_RS13915	COG0737	Belongs to the 5'-nucleotidase family
CLO1100_RS13920	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS13930	COG0697	spore germination
CLO1100_RS13940	COG5002	protein histidine kinase activity
CLO1100_RS13945	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS13950	COG0586	Pfam SNARE associated Golgi protein
CLO1100_RS13960	COG3279	Response regulator of the LytR AlgR family
CLO1100_RS13975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLO1100_RS13975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CLO1100_RS13975	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLO1100_RS13975	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLO1100_RS13995	COG2205	protein histidine kinase activity
CLO1100_RS14000	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS14005	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLO1100_RS14010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLO1100_RS14015	COG5002	protein histidine kinase activity
CLO1100_RS14020	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS14025	COG1136	(ABC) transporter
CLO1100_RS14025	COG0577	efflux transmembrane transporter activity
CLO1100_RS14030	COG1136	(ABC) transporter
CLO1100_RS14040	COG0598	Magnesium transport protein CorA
CLO1100_RS14055	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLO1100_RS14060	COG1968	undecaprenyl-diphosphatase activity
CLO1100_RS14070	COG2801	Transposase and inactivated derivatives
CLO1100_RS14080	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLO1100_RS14135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLO1100_RS14140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS14150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLO1100_RS14175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLO1100_RS14180	COG1472	Belongs to the glycosyl hydrolase 3 family
CLO1100_RS14185	COG0667	Aldo Keto reductase
CLO1100_RS14190	COG2207	Transcriptional regulator
CLO1100_RS14190	COG4753	response regulator
CLO1100_RS14195	COG2972	Histidine kinase
CLO1100_RS14255	COG2323	membrane
CLO1100_RS14265	COG2323	membrane
CLO1100_RS14275	COG1166	arginine decarboxylase activity
CLO1100_RS14285	COG2814	Major facilitator Superfamily
CLO1100_RS14290	COG2814	Major facilitator Superfamily
CLO1100_RS14330	COG1252	NADH dehydrogenase
CLO1100_RS14335	COG3858	chitin binding
CLO1100_RS14335	COG1388	LysM domain
CLO1100_RS14340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLO1100_RS14345	COG1063	alcohol dehydrogenase
CLO1100_RS14350	COG3546	catalase activity
CLO1100_RS14375	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLO1100_RS14375	COG1902	pentaerythritol trinitrate reductase activity
CLO1100_RS14380	COG0640	Transcriptional regulator
CLO1100_RS14395	COG0840	transmembrane signaling receptor activity
CLO1100_RS14410	COG2022	thiamine diphosphate biosynthetic process
CLO1100_RS14420	COG0352	thiamine-phosphate diphosphorylase activity
CLO1100_RS14465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CLO1100_RS14490	COG2818	Glycosylase
CLO1100_RS14495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CLO1100_RS14505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLO1100_RS14510	COG1120	ATPase activity
CLO1100_RS14540	COG0159	tryptophan synthase activity
CLO1100_RS14545	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CLO1100_RS14555	COG1335	isochorismatase
CLO1100_RS14560	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS14565	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS14570	COG3845	ABC transporter
CLO1100_RS14580	COG2188	Transcriptional regulator
CLO1100_RS14585	COG2823	Periplasmic or secreted lipoprotein
CLO1100_RS14585	COG1652	LysM domain
CLO1100_RS14590	COG1079	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS14595	COG4603	Belongs to the binding-protein-dependent transport system permease family
CLO1100_RS14600	COG3845	ABC transporter
CLO1100_RS14605	COG1744	ABC transporter substrate-binding protein PnrA-like
CLO1100_RS14610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLO1100_RS14615	COG1285	pathogenesis
CLO1100_RS14620	COG0584	glycerophosphoryl diester phosphodiesterase
CLO1100_RS14625	COG1069	ribulokinase activity
CLO1100_RS14630	COG1063	alcohol dehydrogenase
CLO1100_RS14640	COG1082	Xylose isomerase domain protein TIM barrel
CLO1100_RS14650	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS14655	COG1175	transmembrane transport
CLO1100_RS14660	COG1609	Transcriptional regulator
CLO1100_RS14665	COG0445	tRNA wobble uridine modification
CLO1100_RS14670	COG3708	Transcriptional regulator
CLO1100_RS14670	COG2207	Transcriptional regulator
CLO1100_RS14685	COG0701	Predicted permease
CLO1100_RS14690	COG0640	Transcriptional regulator
CLO1100_RS14700	COG0535	radical SAM domain protein
CLO1100_RS14725	COG2890	protein-(glutamine-N5) methyltransferase activity
CLO1100_RS14735	COG0535	radical SAM domain protein
CLO1100_RS14740	COG1032	radical SAM domain protein
CLO1100_RS14760	COG1131	(ABC) transporter
CLO1100_RS14785	COG1396	sequence-specific DNA binding
CLO1100_RS14790	COG1396	sequence-specific DNA binding
CLO1100_RS14825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLO1100_RS14830	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS14835	COG1175	transmembrane transport
CLO1100_RS14845	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CLO1100_RS14850	COG2188	Transcriptional regulator
CLO1100_RS14855	COG2731	YhcH YjgK YiaL family protein
CLO1100_RS14865	COG0363	glucosamine-6-phosphate deaminase activity
CLO1100_RS14870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLO1100_RS14880	COG1063	alcohol dehydrogenase
CLO1100_RS14885	COG1082	Xylose isomerase domain protein TIM barrel
CLO1100_RS14890	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS14895	COG1175	transmembrane transport
CLO1100_RS14905	COG2207	Transcriptional regulator
CLO1100_RS14905	COG4753	response regulator
CLO1100_RS14910	COG2972	Histidine kinase
CLO1100_RS14915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLO1100_RS14915	COG2207	Transcriptional regulator
CLO1100_RS14920	COG0445	tRNA wobble uridine modification
CLO1100_RS14925	COG0445	tRNA wobble uridine modification
CLO1100_RS14965	COG1131	(ABC) transporter
CLO1100_RS14980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLO1100_RS15070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLO1100_RS15105	COG0789	Transcriptional regulator
CLO1100_RS15105	COG4978	Transcriptional regulator
CLO1100_RS15110	COG2814	Major facilitator Superfamily
CLO1100_RS15125	COG4172	Belongs to the ABC transporter superfamily
CLO1100_RS15130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLO1100_RS15140	COG0747	negative chemotaxis
CLO1100_RS15150	COG0346	lactoylglutathione lyase activity
CLO1100_RS15155	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS15170	COG1725	Transcriptional regulator
CLO1100_RS15175	COG1131	(ABC) transporter
CLO1100_RS15190	COG1131	(ABC) transporter
CLO1100_RS15215	COG0688	phosphatidylethanolamine metabolic process
CLO1100_RS15245	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS15255	COG2226	methyltransferase
CLO1100_RS15260	COG0840	transmembrane signaling receptor activity
CLO1100_RS15270	COG0785	Cytochrome C biogenesis protein
CLO1100_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
CLO1100_RS15285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLO1100_RS15290	COG1022	Amp-dependent synthetase and ligase
CLO1100_RS15310	COG2373	Large extracellular alpha-helical protein
CLO1100_RS15315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLO1100_RS15320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLO1100_RS15330	COG1592	Rubrerythrin
CLO1100_RS15330	COG1773	rubredoxin
CLO1100_RS15340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLO1100_RS15345	COG2733	membrane
CLO1100_RS15350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLO1100_RS15355	COG0534	Mate efflux family protein
CLO1100_RS15360	COG0318	PFAM AMP-dependent synthetase and ligase
CLO1100_RS15370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLO1100_RS15390	COG0840	transmembrane signaling receptor activity
CLO1100_RS15405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLO1100_RS15410	COG1177	transmembrane transport
CLO1100_RS15415	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLO1100_RS15420	COG3842	ATPase activity
CLO1100_RS15425	COG1396	sequence-specific DNA binding
CLO1100_RS15430	COG1126	abc transporter atp-binding protein
CLO1100_RS15435	COG0765	amino acid transport
CLO1100_RS15440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLO1100_RS15445	COG0739	heme binding
CLO1100_RS15450	COG0726	polysaccharide deacetylase
CLO1100_RS15460	COG1116	anion transmembrane transporter activity
CLO1100_RS15465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLO1100_RS15470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLO1100_RS15475	COG1464	Belongs to the NlpA lipoprotein family
CLO1100_RS15480	COG2011	ABC-type metal ion transport system permease component
CLO1100_RS15485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLO1100_RS15490	COG1959	2 iron, 2 sulfur cluster binding
CLO1100_RS15495	COG1606	tRNA processing
CLO1100_RS15505	COG0546	phosphoglycolate phosphatase activity
CLO1100_RS15510	COG1940	carbohydrate kinase activity
CLO1100_RS15515	COG0673	inositol 2-dehydrogenase activity
CLO1100_RS15540	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLO1100_RS15545	COG1032	radical SAM domain protein
CLO1100_RS15550	COG1032	radical SAM domain protein
CLO1100_RS15555	COG2192	nodulation
CLO1100_RS15580	COG1032	radical SAM domain protein
CLO1100_RS15585	COG4555	ABC transporter
CLO1100_RS15600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLO1100_RS15615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS15620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLO1100_RS15625	COG1216	Glycosyl transferase, family 2
CLO1100_RS15625	COG0463	Glycosyl transferase, family 2
CLO1100_RS15635	COG0662	Cupin 2, conserved barrel domain protein
CLO1100_RS15635	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CLO1100_RS15670	COG1131	(ABC) transporter
CLO1100_RS15715	COG1063	alcohol dehydrogenase
CLO1100_RS15720	COG1063	alcohol dehydrogenase
CLO1100_RS15725	COG1063	alcohol dehydrogenase
CLO1100_RS15735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLO1100_RS15740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLO1100_RS15745	COG2182	Extracellular solute-binding protein
CLO1100_RS15750	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS15755	COG4209	transmembrane transport
CLO1100_RS15760	COG2972	Histidine kinase
CLO1100_RS15770	COG0445	tRNA wobble uridine modification
CLO1100_RS15775	COG2081	HI0933 family
CLO1100_RS15780	COG1082	Xylose isomerase domain protein TIM barrel
CLO1100_RS15830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLO1100_RS15835	COG1022	Amp-dependent synthetase and ligase
CLO1100_RS15850	COG2205	protein histidine kinase activity
CLO1100_RS15865	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS15875	COG2188	Transcriptional regulator
CLO1100_RS15880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLO1100_RS15895	COG2911	Protein conserved in bacteria
CLO1100_RS15895	COG1361	Conserved repeat domain
CLO1100_RS15895	COG3266	domain, Protein
CLO1100_RS15900	COG4821	SIS domain
CLO1100_RS15905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLO1100_RS15920	COG1486	melibiose metabolic process
CLO1100_RS15925	COG2971	BadF BadG BcrA BcrD
CLO1100_RS15935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLO1100_RS15945	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLO1100_RS15960	COG3711	transcriptional antiterminator
CLO1100_RS15960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLO1100_RS15965	COG2996	Protein conserved in bacteria
CLO1100_RS15985	COG0546	phosphoglycolate phosphatase activity
CLO1100_RS15995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLO1100_RS16040	COG0726	polysaccharide deacetylase
CLO1100_RS16110	COG3279	Response regulator of the LytR AlgR family
CLO1100_RS16115	COG2972	Histidine kinase
CLO1100_RS16115	COG0745	RESPONSE REGULATOR receiver
CLO1100_RS16135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLO1100_RS16145	COG1051	belongs to the nudix hydrolase family
CLO1100_RS16160	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLO1100_RS16165	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLO1100_RS16170	COG1469	GTP cyclohydrolase I activity
CLO1100_RS16175	COG0602	queuosine metabolic process
CLO1100_RS16180	COG0720	synthase
CLO1100_RS16190	COG3507	Belongs to the glycosyl hydrolase 43 family
CLO1100_RS16190	COG3693	PFAM glycoside hydrolase, family 10
CLO1100_RS16190	COG2382	esterase
CLO1100_RS16195	COG2207	Transcriptional regulator
CLO1100_RS16195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLO1100_RS16230	COG1396	sequence-specific DNA binding
CLO1100_RS16250	COG1131	(ABC) transporter
CLO1100_RS16350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CLO1100_RS16400	COG4191	Histidine kinase
CLO1100_RS16435	COG0798	PFAM Bile acid sodium symporter
CLO1100_RS16440	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLO1100_RS16445	COG0640	Transcriptional regulator
CLO1100_RS16460	COG2226	methyltransferase
CLO1100_RS16465	COG1846	Transcriptional regulator
CLO1100_RS16660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLO1100_RS16670	COG2088	sporulation resulting in formation of a cellular spore
CLO1100_RS16715	COG0551	DNA topoisomerase type I activity
CLO1100_RS16815	COG0428	transporter
CLO1100_RS16820	COG2217	Heavy metal translocating P-type atpase
CLO1100_RS16830	COG0640	Transcriptional regulator
CLO1100_RS16855	COG0798	PFAM Bile acid sodium symporter
CLO1100_RS16860	COG0640	Transcriptional regulator
CLO1100_RS16865	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLO1100_RS16870	COG0640	Transcriptional regulator
CLO1100_RS16880	COG2226	methyltransferase
CLO1100_RS16885	COG1846	Transcriptional regulator
CLO1100_RS16990	COG0270	DNA (cytosine-5-)-methyltransferase activity
CLO1100_RS17020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLO1100_RS17080	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLO1100_RS17090	COG2088	sporulation resulting in formation of a cellular spore
CLO1100_RS17210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLO1100_RS17210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLO1100_RS17245	COG4824	toxin secretion phage lysis holin
CLO1100_RS17320	COG4695	Portal protein
CLO1100_RS17330	COG1802	Transcriptional regulator
CLO1100_RS17330	COG4626	Terminase
CLO1100_RS17435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CLO1100_RS17485	COG0840	transmembrane signaling receptor activity
CLO1100_RS17490	COG0739	heme binding
CLO1100_RS17515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLO1100_RS17520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CLO1100_RS17525	COG0287	Prephenate dehydrogenase
CLO1100_RS17530	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CLO1100_RS17540	COG0488	(ABC) transporter
CLO1100_RS17550	COG0840	transmembrane signaling receptor activity
CLO1100_RS17560	COG0840	transmembrane signaling receptor activity
CLO1100_RS17565	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLO1100_RS17635	COG1131	(ABC) transporter
CLO1100_RS17675	COG1151	hydroxylamine reductase activity
CLO1100_RS17705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLO1100_RS17710	COG1278	Cold shock
CLO1100_RS17730	COG0739	heme binding
CLO1100_RS17735	COG2177	Part of the ABC transporter FtsEX involved in
CLO1100_RS17740	COG2884	Cell division ATP-binding protein ftsE
CLO1100_RS17745	COG3835	regulator
CLO1100_RS17775	COG3842	ATPase activity
CLO1100_RS17780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLO1100_RS17785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLO1100_RS17790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLO1100_RS17795	COG0505	Belongs to the CarA family
CLO1100_RS17800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLO1100_RS17805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLO1100_RS17820	COG1151	hydroxylamine reductase activity
CLO1100_RS17830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLO1100_RS17850	COG2337	Toxic component of a toxin-antitoxin (TA) module
CLO1100_RS17855	COG0864	Transcriptional regulator
CLO1100_RS17860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLO1100_RS17865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLO1100_RS17865	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLO1100_RS17875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLO1100_RS17905	COG2816	NAD+ diphosphatase activity
CLO1100_RS17910	COG0071	Belongs to the small heat shock protein (HSP20) family
CLO1100_RS17915	COG2244	polysaccharide biosynthetic process
CLO1100_RS17920	COG1388	LysM domain
CLO1100_RS17920	COG0791	NLP P60 protein
CLO1100_RS17925	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLO1100_RS17930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLO1100_RS18045	COG2208	phosphoserine phosphatase activity
CLO1100_RS18050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLO1100_RS18055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLO1100_RS18090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLO1100_RS18100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLO1100_RS18105	COG1550	Protein conserved in bacteria
CLO1100_RS18115	COG1671	Belongs to the UPF0178 family
CLO1100_RS18120	COG4124	Belongs to the glycosyl hydrolase 26 family
CLO1100_RS18125	COG0395	ABC-type sugar transport system, permease component
CLO1100_RS18130	COG1175	transmembrane transport
CLO1100_RS18145	COG1609	Transcriptional regulator
CLO1100_RS18150	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CLO1100_RS18155	COG2942	2-epimerase
CLO1100_RS18160	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CLO1100_RS18165	COG3458	cephalosporin-C deacetylase activity
CLO1100_RS18175	COG0701	Predicted permease
CLO1100_RS18180	COG0523	cobalamin synthesis protein
CLO1100_RS18190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLO1100_RS18215	COG0318	PFAM AMP-dependent synthetase and ligase
CLO1100_RS18220	COG1053	succinate dehydrogenase
CLO1100_RS18220	COG3976	FMN-binding domain protein
CLO1100_RS18225	COG1477	protein flavinylation
CLO1100_RS18230	COG1309	transcriptional regulator
CLO1100_RS18235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLO1100_RS18250	COG0697	spore germination
CLO1100_RS18260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLO1100_RS18295	COG3299	homolog of phage Mu protein gp47
CLO1100_RS18350	COG1396	sequence-specific DNA binding
CLO1100_RS18360	COG1098	S1 RNA binding domain
CLO1100_RS18380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLO1100_RS18390	COG3956	TIGRFAM MazG family protein
CLO1100_RS18400	COG2002	toxin-antitoxin pair type II binding
CLO1100_RS18405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLO1100_RS18410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLO1100_RS18415	COG0193	aminoacyl-tRNA hydrolase activity
CLO1100_RS18425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLO1100_RS18430	COG2088	sporulation resulting in formation of a cellular spore
CLO1100_RS18435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLO1100_RS18440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLO1100_RS18445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLO1100_RS18455	COG3951	Flagellar rod assembly protein muramidase FlgJ
CLO1100_RS18465	COG4786	Flagellar basal body rod
CLO1100_RS18475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLO1100_RS18500	COG0475	glutathione-regulated potassium exporter activity
CLO1100_RS18505	COG0490	domain, Protein
CLO1100_RS18515	COG1609	Transcriptional regulator
CLO1100_RS18525	COG1819	glycosyl
CLO1100_RS18535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLO1100_RS18545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CLO1100_RS18560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLO1100_RS18565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLO1100_RS18575	COG2801	Transposase and inactivated derivatives
CLO1100_RS18595	COG1802	Transcriptional regulator
CLO1100_RS18610	COG1012	belongs to the aldehyde dehydrogenase family
CLO1100_RS18610	COG1454	alcohol dehydrogenase
CLO1100_RS18615	COG5012	cobalamin binding
CLO1100_RS18635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLO1100_RS18645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLO1100_RS18650	COG2843	Capsule synthesis protein
CLO1100_RS18655	COG1368	sulfuric ester hydrolase activity
CLO1100_RS18690	COG0512	Glutamine amidotransferase of anthranilate synthase
CLO1100_RS18690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLO1100_RS18695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLO1100_RS18700	COG0134	indole-3-glycerol-phosphate synthase activity
CLO1100_RS18705	COG0135	phosphoribosylanthranilate isomerase activity
CLO1100_RS18710	COG0133	tryptophan synthase activity
CLO1100_RS18715	COG0159	tryptophan synthase activity
CLO1100_RS18730	COG0457	Tetratricopeptide repeat
CLO1100_RS18730	COG0463	Glycosyl transferase, family 2
CLO1100_RS18735	COG4989	oxidoreductase activity
CLO1100_RS18750	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLO1100_RS18755	COG0840	transmembrane signaling receptor activity
CLO1100_RS18770	COG2357	RelA SpoT domain protein
CLO1100_RS18785	COG1073	alpha beta
CLO1100_RS18795	COG0488	(ABC) transporter
CLO1100_RS18800	COG1573	uracil-dna glycosylase
CLO1100_RS18805	COG1268	BioY protein
CLO1100_RS18820	COG0840	transmembrane signaling receptor activity
CLO1100_RS18855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLO1100_RS18865	COG0708	Exodeoxyribonuclease III
CLO1100_RS18875	COG0215	cysteine-tRNA ligase activity
CLO1100_RS18910	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CLO1100_RS18925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLO1100_RS18940	COG0697	spore germination
CLO1100_RS18945	COG1979	alcohol dehydrogenase
CLO1100_RS18950	COG0789	Transcriptional regulator
CLO1100_RS18960	COG2204	response regulator
CLO1100_RS18965	COG5002	protein histidine kinase activity
CLO1100_RS18970	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CLO1100_RS18975	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CLO1100_RS18980	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLO1100_RS18985	COG2205	protein histidine kinase activity
CLO1100_RS19005	COG2155	Conserved Protein
CLO1100_RS19015	COG0628	permease
CLO1100_RS19035	COG0671	phosphoesterase, PA-phosphatase related
CLO1100_RS19045	COG1653	transport
CLO1100_RS19050	COG1132	(ABC) transporter
CLO1100_RS19075	COG0668	transmembrane transport
CLO1100_RS19080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CLO1100_RS19085	COG1773	rubredoxin
CLO1100_RS19110	COG0024	Methionine aminopeptidase
CLO1100_RS19120	COG2860	membrane
CLO1100_RS19125	COG0375	protein maturation
CLO1100_RS19135	COG3261	NADH dehydrogenase
CLO1100_RS19135	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CLO1100_RS19140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLO1100_RS19145	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLO1100_RS19150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLO1100_RS19155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLO1100_RS19155	COG2111	Na H antiporter
CLO1100_RS19160	COG0628	permease
CLO1100_RS19165	COG2890	protein-(glutamine-N5) methyltransferase activity
CLO1100_RS19170	COG3872	metal-dependent enzyme
CLO1100_RS19175	COG0254	rRNA binding
CLO1100_RS19180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLO1100_RS19200	COG0813	purine-nucleoside phosphorylase activity
CLO1100_RS19205	COG1368	sulfuric ester hydrolase activity
CLO1100_RS19215	COG2078	PFAM AMMECR1 domain protein
CLO1100_RS19215	COG3885	ferrous iron binding
CLO1100_RS19220	COG2235	arginine
CLO1100_RS19230	COG2205	protein histidine kinase activity
CLO1100_RS19235	COG0534	Mate efflux family protein
CLO1100_RS19245	COG1131	(ABC) transporter
CLO1100_RS19250	COG0789	Transcriptional regulator
CLO1100_RS19260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLO1100_RS19265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLO1100_RS19270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLO1100_RS19290	COG5002	protein histidine kinase activity
CLO1100_RS19325	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLO1100_RS19330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLO1100_RS19335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLO1100_RS19340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLO1100_RS19365	COG0037	tRNA processing
CLO1100_RS19375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLO1100_RS19405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLO1100_RS19410	COG1121	(ABC) transporter
CLO1100_RS19425	COG3655	Transcriptional regulator
CLO1100_RS19450	COG3973	AAA domain
CLO1100_RS19475	COG2226	methyltransferase
CLO1100_RS19480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLO1100_RS19485	COG2011	ABC-type metal ion transport system permease component
CLO1100_RS19490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLO1100_RS19500	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLO1100_RS19505	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLO1100_RS19520	COG0436	Aminotransferase
CLO1100_RS19525	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CLO1100_RS19530	COG1486	melibiose metabolic process
CLO1100_RS19540	COG2207	Transcriptional regulator
CLO1100_RS19545	COG0534	Mate efflux family protein
CLO1100_RS19550	COG2115	Belongs to the xylose isomerase family
CLO1100_RS19555	COG1940	carbohydrate kinase activity
CLO1100_RS19560	COG1070	Carbohydrate kinase
CLO1100_RS19570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLO1100_RS19575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLO1100_RS19580	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLO1100_RS19585	COG0440	acetolactate synthase activity
CLO1100_RS19590	COG0028	Belongs to the TPP enzyme family
CLO1100_RS19605	COG0590	tRNA wobble adenosine to inosine editing
CLO1100_RS19615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLO1100_RS19655	COG0022	dehydrogenase e1 component
CLO1100_RS19660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLO1100_RS19680	COG0463	Glycosyl transferase, family 2
CLO1100_RS19690	COG0495	leucyl-tRNA aminoacylation
CLO1100_RS19705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLO1100_RS19710	COG2309	aminopeptidase activity
CLO1100_RS19715	COG1164	Oligoendopeptidase f
CLO1100_RS19745	COG1609	Transcriptional regulator
CLO1100_RS19775	COG1609	Transcriptional regulator
CLO1100_RS19780	COG0432	Pfam Uncharacterised protein family UPF0047
CLO1100_RS19785	COG1489	DNA binding
CLO1100_RS19790	COG2033	superoxide reductase activity
CLO1100_RS19795	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLO1100_RS19820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLO1100_RS19825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLO1100_RS19830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CLO1100_RS19830	COG1918	ferrous iron import across plasma membrane
CLO1100_RS19865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLO1100_RS19870	COG1475	DNA binding
CLO1100_RS19875	COG0357	Ribosomal RNA small subunit methyltransferase G
CLO1100_RS19880	COG0445	tRNA wobble uridine modification
CLO1100_RS19885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLO1100_RS19890	COG1847	R3H domain protein
CLO1100_RS19895	COG0706	membrane insertase activity
CLO1100_RS19900	COG0594	ribonuclease P activity
CLO1100_RS19905	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CLO1100_RS19920	COG0515	serine threonine protein kinase
CLO1100_RS19920	COG2815	serine threonine protein kinase
CLO1100_RS19945	COG1395	domain, Protein
CLO1100_RS19950	COG3935	DnaD domain protein
CLO1100_RS19975	COG0582	viral genome integration into host DNA
CLO1100_RS19980	COG1396	sequence-specific DNA binding
CLO1100_RS19985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLO1100_RS20015	COG1396	sequence-specific DNA binding
CLO1100_RS20020	COG2207	Transcriptional regulator
CLO1100_RS20020	COG0662	Cupin 2, conserved barrel domain protein
CLO1100_RS20045	COG0667	Aldo Keto reductase
CLO1100_RS20065	COG3693	PFAM glycoside hydrolase, family 10