CLOSPO_RS04555 44c2a6e47a3f0f50a474a97b045be62e 234 PANTHER PTHR11082:SF32 1 234 3.8E-154 T 09-11-2016 CLOSPO_RS04555 44c2a6e47a3f0f50a474a97b045be62e 234 Gene3D G3DSA:3.20.20.70 2 158 2.0E-32 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS04555 44c2a6e47a3f0f50a474a97b045be62e 234 SUPERFAMILY SSF51395 3 215 2.69E-30 T 09-11-2016 CLOSPO_RS04555 44c2a6e47a3f0f50a474a97b045be62e 234 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 9 27 - T 09-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS04555 44c2a6e47a3f0f50a474a97b045be62e 234 Pfam PF01207 Dihydrouridine synthase (Dus) 3 222 6.1E-28 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS04555 44c2a6e47a3f0f50a474a97b045be62e 234 PANTHER PTHR11082 1 234 3.8E-154 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 SMART SM00729 26 253 3.0E-42 T 09-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 Pfam PF04055 Radical SAM superfamily 46 209 3.8E-19 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 PANTHER PTHR11135:SF1 6 310 5.0E-152 T 09-11-2016 IPR005911 Protein YhcC-like GO:0051536 CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 PANTHER PTHR11135 6 310 5.0E-152 T 09-11-2016 CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 Gene3D G3DSA:3.80.30.20 26 253 2.1E-34 T 09-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 10 308 3.0E-118 T 09-11-2016 IPR005911 Protein YhcC-like GO:0051536 CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 Pfam PF16199 Radical_SAM C-terminal domain 214 298 8.6E-28 T 09-11-2016 IPR032432 Radical SAM, C-terminal extension CLOSPO_RS15090 870e61e34271002bb7be90cd62024231 310 SUPERFAMILY SSF102114 10 296 3.4E-53 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 PANTHER PTHR10617 2 299 9.1E-113 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 Gene3D G3DSA:2.40.30.10 189 280 2.1E-18 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 404 8.3E-140 T 09-11-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 PANTHER PTHR10617:SF103 2 299 9.1E-113 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 PANTHER PTHR10617 342 406 9.1E-113 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 Gene3D G3DSA:3.50.50.60 351 405 2.3E-43 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 Gene3D G3DSA:3.50.50.60 4 186 2.3E-43 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 Pfam PF03486 HI0933-like protein 4 404 1.9E-129 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 PANTHER PTHR10617:SF103 342 406 9.1E-113 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 SUPERFAMILY SSF160996 189 352 9.81E-45 T 09-11-2016 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 SUPERFAMILY SSF51905 349 406 4.23E-46 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14730 c1fe9a0fde7a2fe1590597a7316dc448 409 SUPERFAMILY SSF51905 4 187 4.23E-46 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14145 ba380e80579c47b63195d02bb0ed73df 78 PIRSF PIRSF037257 1 78 7.8E-33 T 09-11-2016 IPR009366 Protein Veg GO:0042710 CLOSPO_RS14145 ba380e80579c47b63195d02bb0ed73df 78 PANTHER PTHR40026 2 77 9.6E-32 T 09-11-2016 CLOSPO_RS14145 ba380e80579c47b63195d02bb0ed73df 78 Pfam PF06257 Biofilm formation stimulator VEG 6 74 1.0E-29 T 09-11-2016 IPR009366 Protein Veg GO:0042710 CLOSPO_RS14145 ba380e80579c47b63195d02bb0ed73df 78 PANTHER PTHR40026:SF1 2 77 9.6E-32 T 09-11-2016 IPR009366 Protein Veg GO:0042710 CLOSPO_RS14145 ba380e80579c47b63195d02bb0ed73df 78 Gene3D G3DSA:2.30.30.100 2 76 6.2E-30 T 09-11-2016 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 1.0E-12 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 473 1.0E-12 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 1.0E-12 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 1.0E-12 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 SUPERFAMILY SSF55874 311 473 1.01E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 Gene3D G3DSA:1.10.287.130 247 312 4.3E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PANTHER PTHR24423:SF470 189 473 8.0E-191 T 09-11-2016 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 Gene3D G3DSA:3.30.565.10 327 471 1.4E-33 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PANTHER PTHR24423 1 127 8.0E-191 T 09-11-2016 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 SMART SM00387 367 473 3.0E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PANTHER PTHR24423:SF470 1 127 8.0E-191 T 09-11-2016 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 471 3.6E-20 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 SUPERFAMILY SSF47384 238 321 2.55E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 PANTHER PTHR24423 189 473 8.0E-191 T 09-11-2016 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 SMART SM00388 253 321 1.1E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18265 0369912bd89ac5913e8ed640830b73fe 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 316 7.4E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12805 598607bc2fbedb448d9e7752faa2b781 192 PANTHER PTHR30335:SF0 1 192 3.1E-117 T 09-11-2016 CLOSPO_RS12805 598607bc2fbedb448d9e7752faa2b781 192 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 1 190 5.8E-81 T 09-11-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 CLOSPO_RS12805 598607bc2fbedb448d9e7752faa2b781 192 PIRSF PIRSF006102 1 192 4.8E-57 T 09-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CLOSPO_RS12805 598607bc2fbedb448d9e7752faa2b781 192 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 1 191 25.17 T 09-11-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 CLOSPO_RS12805 598607bc2fbedb448d9e7752faa2b781 192 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 190 4.9E-62 T 09-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CLOSPO_RS12805 598607bc2fbedb448d9e7752faa2b781 192 PANTHER PTHR30335 1 192 3.1E-117 T 09-11-2016 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SUPERFAMILY SSF50249 122 221 5.3E-20 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Pfam PF00575 S1 RNA binding domain 620 691 3.1E-14 T 09-11-2016 IPR003029 S1 domain GO:0003676 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Gene3D G3DSA:2.40.50.140 622 712 1.2E-23 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 54 702 3.4E-226 T 09-11-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Hamap MF_01895 Ribonuclease R [rnr]. 21 702 59.015 T 09-11-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SMART SM00316 620 702 1.7E-14 T 09-11-2016 IPR022967 RNA-binding domain, S1 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SMART SM00316 131 195 9.8 T 09-11-2016 IPR022967 RNA-binding domain, S1 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 PANTHER PTHR23355 5 713 3.2E-263 T 09-11-2016 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SMART SM00357 69 129 1.3E-13 T 09-11-2016 IPR011129 Cold shock protein GO:0003676 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SMART SM00357 134 198 6.0E-8 T 09-11-2016 IPR011129 Cold shock protein GO:0003676 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SUPERFAMILY SSF50249 50 131 7.4E-20 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Gene3D G3DSA:1.10.10.10 2 57 0.001 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 PANTHER PTHR23355:SF9 5 713 3.2E-263 T 09-11-2016 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SMART SM00955 244 573 1.7E-183 T 09-11-2016 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Pfam PF08206 Ribonuclease B OB domain 144 197 2.9E-7 T 09-11-2016 IPR013223 Ribonuclease B, N-terminal OB domain CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Pfam PF08206 Ribonuclease B OB domain 70 128 2.0E-23 T 09-11-2016 IPR013223 Ribonuclease B, N-terminal OB domain CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 Pfam PF00773 RNB domain 244 572 2.9E-118 T 09-11-2016 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SUPERFAMILY SSF50249 205 619 6.28E-149 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 702 2.1E-283 T 09-11-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CLOSPO_RS13545 1c10514851cc8716dfa250e32be0f67c 725 SUPERFAMILY SSF50249 620 714 1.72E-22 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Gene3D G3DSA:3.40.50.620 389 624 1.3E-143 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Gene3D G3DSA:3.40.50.620 6 194 1.3E-143 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 221 244 2.1E-29 T 09-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 2.1E-29 T 09-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 2.1E-29 T 09-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 2.1E-29 T 09-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 2.1E-29 T 09-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PANTHER PTHR11946:SF87 262 925 0.0 T 09-11-2016 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PANTHER PTHR11946:SF87 1 242 0.0 T 09-11-2016 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 619 4.4E-189 T 09-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 09-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PANTHER PTHR11946 262 925 0.0 T 09-11-2016 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 PANTHER PTHR11946 1 242 0.0 T 09-11-2016 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 7 833 9.2E-295 T 09-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 SUPERFAMILY SSF52374 386 638 3.38E-135 T 09-11-2016 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 SUPERFAMILY SSF52374 9 198 3.38E-135 T 09-11-2016 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 SUPERFAMILY SSF47323 645 881 9.16E-57 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 SUPERFAMILY SSF47323 952 1033 2.62E-6 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Gene3D G3DSA:1.10.730.10 629 819 2.3E-56 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1038 14.231 T 09-11-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 SUPERFAMILY SSF50677 199 386 3.92E-52 T 09-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Pfam PF08264 Anticodon-binding domain of tRNA 676 827 1.8E-37 T 09-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 CLOSPO_RS14230 bfc53e3afae03de8a7252994d5bd4a8c 1038 Gene3D G3DSA:3.90.740.10 202 372 5.2E-58 T 09-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 SMART SM00855 2 161 1.4E-21 T 09-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 09-11-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 PIRSF PIRSF000709 1 176 1.2E-21 T 09-11-2016 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 3 186 3.9E-63 T 09-11-2016 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 PANTHER PTHR23029 1 201 3.0E-109 T 09-11-2016 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 193 2.0E-54 T 09-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 SUPERFAMILY SSF53254 1 192 2.23E-57 T 09-11-2016 IPR029033 Histidine phosphatase superfamily CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 PANTHER PTHR23029:SF33 1 201 3.0E-109 T 09-11-2016 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 Gene3D G3DSA:3.40.50.1240 1 191 3.1E-60 T 09-11-2016 IPR029033 Histidine phosphatase superfamily CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 PRINTS PR00991 6-phosphofructo-2-kinase family signature 90 106 6.8E-5 T 09-11-2016 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|KEGG: 00500+2.7.1.10|Reactome: REACT_474 CLOSPO_RS17500 8f42eb087b649e92005ef57e00ca5c91 204 PRINTS PR00991 6-phosphofructo-2-kinase family signature 3 25 6.8E-5 T 09-11-2016 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|KEGG: 00500+2.7.1.10|Reactome: REACT_474 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 SMART SM00345 17 76 6.8E-14 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 SUPERFAMILY SSF46785 7 84 6.98E-21 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 SUPERFAMILY SSF53383 114 480 8.91E-85 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 Gene3D G3DSA:3.40.640.10 147 361 7.1E-68 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 3.0E-13 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 Pfam PF00155 Aminotransferase class I and II 132 467 2.5E-32 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 PANTHER PTHR11751:SF301 93 477 4.2E-140 T 09-11-2016 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 Gene3D G3DSA:1.10.10.10 4 77 4.9E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 Gene3D G3DSA:3.90.1150.10 362 477 3.2E-6 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 PANTHER PTHR11751 93 477 4.2E-140 T 09-11-2016 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.2E-6 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS15645 6fd3f665979e8201e652b4d051d48842 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.2E-6 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 Gene3D G3DSA:1.10.3860.10 4 409 2.4E-77 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PANTHER PTHR11958 2 409 2.7E-259 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 Pfam PF00375 Sodium:dicarboxylate symporter family 13 403 2.6E-95 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.6E-18 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.6E-18 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 1.6E-18 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.6E-18 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 1.6E-18 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 1.6E-18 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 SUPERFAMILY SSF118215 11 403 7.32E-84 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS16170 3231fa3e209b92511b33431740d57acd 416 PANTHER PTHR11958:SF61 2 409 2.7E-259 T 09-11-2016 CLOSPO_RS17425 4c87622c24f612ac468d48a92a4820fb 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 320 2.4E-96 T 09-11-2016 IPR002729 CRISPR-associated protein Cas1 CLOSPO_RS17425 4c87622c24f612ac468d48a92a4820fb 326 Pfam PF01867 CRISPR associated protein Cas1 5 281 8.9E-89 T 09-11-2016 IPR002729 CRISPR-associated protein Cas1 CLOSPO_RS17425 4c87622c24f612ac468d48a92a4820fb 326 PANTHER PTHR34353:SF3 1 326 2.4E-169 T 09-11-2016 CLOSPO_RS17425 4c87622c24f612ac468d48a92a4820fb 326 PANTHER PTHR34353 1 326 2.4E-169 T 09-11-2016 CLOSPO_RS17425 4c87622c24f612ac468d48a92a4820fb 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 4 322 20.807 T 09-11-2016 IPR002729 CRISPR-associated protein Cas1 CLOSPO_RS17425 4c87622c24f612ac468d48a92a4820fb 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 326 3.4E-137 T 09-11-2016 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 Pfam PF00580 UvrD/REP helicase N-terminal domain 83 287 3.7E-6 T 09-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 SUPERFAMILY SSF52540 1 79 3.05E-19 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 SUPERFAMILY SSF52540 120 288 3.05E-19 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 PANTHER PTHR11070 182 290 1.6E-100 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 PANTHER PTHR11070 1 126 1.6E-100 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 PANTHER PTHR11070:SF18 182 290 1.6E-100 T 09-11-2016 CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 PANTHER PTHR11070:SF18 1 126 1.6E-100 T 09-11-2016 CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 Gene3D G3DSA:3.40.50.300 228 288 5.7E-16 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07825 c413d4ddc63d1a79e9163f00e3872b78 290 Gene3D G3DSA:3.40.50.300 1 66 5.7E-16 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 09-11-2016 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 PANTHER PTHR11441 1 187 1.7E-92 T 09-11-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 SUPERFAMILY SSF52540 8 141 4.2E-44 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 Gene3D G3DSA:3.30.60.20 142 187 2.2E-16 T 09-11-2016 CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 SUPERFAMILY SSF57716 142 190 3.99E-16 T 09-11-2016 CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 PIRSF PIRSF035805 5 191 5.1E-69 T 09-11-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 Pfam PF00265 Thymidine kinase 8 187 7.9E-60 T 09-11-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 CLOSPO_RS14045 faa029cd4cc2b75a7262193e2873ce63 191 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.8 T 09-11-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.6E-10 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.6E-10 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 SMART SM00895 98 223 2.4E-17 T 09-11-2016 IPR011711 GntR, C-terminal CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 Gene3D G3DSA:1.10.10.10 7 75 1.4E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 Gene3D G3DSA:1.20.120.530 97 228 4.4E-27 T 09-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 PANTHER PTHR11751 91 114 2.3E-49 T 09-11-2016 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 SUPERFAMILY SSF48008 96 227 8.89E-24 T 09-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 PANTHER PTHR11751 1 75 2.3E-49 T 09-11-2016 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 Pfam PF07729 FCD domain 98 222 2.2E-23 T 09-11-2016 IPR011711 GntR, C-terminal CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 SUPERFAMILY SSF46785 5 77 8.24E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 7.7E-22 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 PANTHER PTHR11751:SF382 91 114 2.3E-49 T 09-11-2016 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 PANTHER PTHR11751:SF382 1 75 2.3E-49 T 09-11-2016 CLOSPO_RS18965 1f13c8577847b15f98f06e8a8acb38b4 230 SMART SM00345 14 73 3.5E-21 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 SUPERFAMILY SSF52540 181 430 1.59E-53 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 PANTHER PTHR30153 5 444 7.0E-207 T 09-11-2016 CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 8 438 5.1E-178 T 09-11-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 Gene3D G3DSA:3.40.50.300 170 439 3.1E-108 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 Pfam PF03796 DnaB-like helicase C terminal domain 183 437 3.8E-115 T 09-11-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 Pfam PF00772 DnaB-like helicase N terminal domain 8 109 8.7E-33 T 09-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 SUPERFAMILY SSF48024 6 118 7.85E-34 T 09-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 Gene3D G3DSA:1.10.860.10 8 110 1.6E-33 T 09-11-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CLOSPO_RS14695 ec7d374905b31fa1b0f3b57a9699b1b0 444 SMART SM00382 200 378 4.3E-4 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 PANTHER PTHR10859 5 88 4.6E-29 T 09-11-2016 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 PANTHER PTHR10859:SF99 5 88 4.6E-29 T 09-11-2016 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 Gene3D G3DSA:1.25.40.10 204 338 9.4E-12 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 SUPERFAMILY SSF48452 381 483 7.59E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 Pfam PF00535 Glycosyl transferase family 2 6 104 4.1E-20 T 09-11-2016 IPR001173 Glycosyltransferase 2-like CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 SUPERFAMILY SSF48452 203 410 1.71E-13 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 Gene3D G3DSA:1.25.40.10 339 479 7.5E-8 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 Gene3D G3DSA:1.25.40.10 524 581 7.5E-8 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 Gene3D G3DSA:3.90.550.10 5 111 5.2E-17 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 SUPERFAMILY SSF53448 5 120 1.08E-25 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS18780 a3739fcb6e265fc8a7154bd874bb4088 597 Pfam PF13181 Tetratricopeptide repeat 275 303 0.01 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 PANTHER PTHR30294:SF4 514 715 1.3E-77 T 09-11-2016 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 PANTHER PTHR30294:SF4 1 230 1.3E-77 T 09-11-2016 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 499 700 5.7E-46 T 09-11-2016 IPR017501 Phage infection protein, YhgE, C-terminal CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 PANTHER PTHR30294 514 715 1.3E-77 T 09-11-2016 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 SUPERFAMILY SSF58104 188 431 7.32E-6 T 09-11-2016 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 170 6.3E-46 T 09-11-2016 IPR017500 Phage infection protein, YhgE, N-terminal CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 Pfam PF12698 ABC-2 family transporter protein 23 163 1.5E-8 T 09-11-2016 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 Pfam PF12698 ABC-2 family transporter protein 326 698 5.8E-13 T 09-11-2016 CLOSPO_RS18380 8d83234dfc49b478fa7ae57604c6c708 719 PANTHER PTHR30294 1 230 1.3E-77 T 09-11-2016 CLOSPO_RS14040 962e8d5df930828c50a40dd8d7f1d3c8 305 Pfam PF07136 Protein of unknown function (DUF1385) 54 297 9.9E-93 T 09-11-2016 IPR010787 Protein of unknown function DUF1385 CLOSPO_RS14040 962e8d5df930828c50a40dd8d7f1d3c8 305 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 54 301 2.0E-89 T 09-11-2016 IPR010787 Protein of unknown function DUF1385 CLOSPO_RS14040 962e8d5df930828c50a40dd8d7f1d3c8 305 PANTHER PTHR31223 145 253 5.1E-40 T 09-11-2016 CLOSPO_RS14040 962e8d5df930828c50a40dd8d7f1d3c8 305 PANTHER PTHR31223:SF5 145 253 5.1E-40 T 09-11-2016 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 Gene3D G3DSA:3.20.20.70 2 237 6.6E-45 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 Pfam PF01207 Dihydrouridine synthase (Dus) 5 302 3.5E-35 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 PIRSF PIRSF006621 1 316 1.0E-60 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 SUPERFAMILY SSF51395 1 294 3.88E-43 T 09-11-2016 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 PANTHER PTHR11082:SF32 1 319 1.2E-211 T 09-11-2016 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 88 106 - T 09-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS16840 3d5ab2170b9317507f6de057d6d2fb9e 319 PANTHER PTHR11082 1 319 1.2E-211 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 PIRSF PIRSF026782 9 359 2.8E-124 T 09-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 Gene3D G3DSA:3.30.2110.10 15 183 3.4E-60 T 09-11-2016 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 PANTHER PTHR35863 2 359 3.0E-122 T 09-11-2016 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 20 358 1.2E-86 T 09-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 SUPERFAMILY SSF111342 3 284 4.84E-87 T 09-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 PANTHER PTHR35863:SF1 2 359 3.0E-122 T 09-11-2016 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 13 357 29.218 T 09-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18090 7dd1815b8bd783927625aa935c9da6d0 359 Pfam PF01888 CbiD 13 267 1.1E-96 T 09-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 113 123 - T 09-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 PANTHER PTHR10795:SF419 56 395 2.4E-41 T 09-11-2016 CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 PANTHER PTHR10795 56 395 2.4E-41 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 108 127 5.7E-12 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 161 5.7E-12 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 340 356 5.7E-12 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 Gene3D G3DSA:3.40.50.200 97 397 8.1E-50 T 09-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 SUPERFAMILY SSF52743 103 397 6.94E-53 T 09-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 Pfam PF00082 Subtilase family 108 362 9.4E-21 T 09-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CLOSPO_RS14890 67d25b99a918a5e90e59942c66b0979b 398 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 152 162 - T 09-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site CLOSPO_RS16820 150f964a1c04c4621bf51c51a4c67243 737 PANTHER PTHR34978:SF2 140 355 3.9E-40 T 09-11-2016 CLOSPO_RS16820 150f964a1c04c4621bf51c51a4c67243 737 PANTHER PTHR34978 140 355 3.9E-40 T 09-11-2016 CLOSPO_RS16820 150f964a1c04c4621bf51c51a4c67243 737 Pfam PF05569 BlaR1 peptidase M56 11 330 5.2E-52 T 09-11-2016 IPR008756 Peptidase M56 CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 SMART SM00382 28 217 7.0E-20 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 Pfam PF00005 ABC transporter 20 167 2.7E-32 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 Gene3D G3DSA:3.40.50.300 3 240 5.4E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 SUPERFAMILY SSF52540 4 230 4.58E-61 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 PANTHER PTHR24220:SF438 5 258 2.0E-156 T 09-11-2016 CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16880 d9dd0504ae756e955a5066588da2019c 261 PANTHER PTHR24220 5 258 2.0E-156 T 09-11-2016 CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 SUPERFAMILY SSF46785 12 82 3.63E-16 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 SMART SM00345 19 78 4.3E-7 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 SUPERFAMILY SSF53383 105 477 4.7E-73 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 Pfam PF00155 Aminotransferase class I and II 126 443 1.0E-23 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 Gene3D G3DSA:1.10.10.10 6 79 6.0E-20 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 Gene3D G3DSA:3.40.640.10 150 367 8.1E-46 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 PANTHER PTHR11751:SF10 99 478 1.9E-138 T 09-11-2016 CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 1.7E-8 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS17735 39b40b02a8ad5f1882f92de626578489 478 PANTHER PTHR11751 99 478 1.9E-138 T 09-11-2016 CLOSPO_RS18910 ba4bd0019a39861f16fb0889e43adffc 73 SMART SM00899 1 73 6.5E-21 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS18910 ba4bd0019a39861f16fb0889e43adffc 73 PANTHER PTHR33238 1 73 6.1E-19 T 09-11-2016 CLOSPO_RS18910 ba4bd0019a39861f16fb0889e43adffc 73 SUPERFAMILY SSF50037 5 72 2.27E-18 T 09-11-2016 IPR008988 Transcriptional repressor, C-terminal CLOSPO_RS18910 ba4bd0019a39861f16fb0889e43adffc 73 Pfam PF04023 FeoA domain 1 72 9.1E-16 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS16180 de83e5e626e6e6b8923319bda0ec868c 334 Pfam PF02517 CAAX protease self-immunity 182 281 8.4E-17 T 09-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 CLOSPO_RS16180 de83e5e626e6e6b8923319bda0ec868c 334 PANTHER PTHR35797:SF1 40 334 2.3E-48 T 09-11-2016 CLOSPO_RS16180 de83e5e626e6e6b8923319bda0ec868c 334 PANTHER PTHR35797 40 334 2.3E-48 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 Gene3D G3DSA:3.30.450.20 163 304 5.7E-33 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 SUPERFAMILY SSF58104 414 683 8.63E-73 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 SUPERFAMILY SSF58104 347 381 8.63E-73 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 SUPERFAMILY SSF103190 58 207 4.0E-8 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 Gene3D G3DSA:1.10.287.950 423 639 2.5E-55 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 SMART SM00283 394 683 4.0E-80 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 PANTHER PTHR32089:SF36 80 684 9.1E-302 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 PANTHER PTHR32089 80 684 9.1E-302 T 09-11-2016 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 Pfam PF00672 HAMP domain 308 375 1.3E-11 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 Pfam PF02743 Cache domain 38 289 6.0E-32 T 09-11-2016 IPR033479 Double Cache domain 1 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 465 669 1.4E-51 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS12655 66a7c64fcced4bda354d75b03059e39c 684 SMART SM00304 327 379 2.4E-5 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 Pfam PF00005 ABC transporter 341 488 5.7E-32 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 Gene3D G3DSA:1.20.1560.10 3 307 7.8E-48 T 09-11-2016 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 PANTHER PTHR24221 5 557 3.2E-130 T 09-11-2016 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 Pfam PF00664 ABC transporter transmembrane region 12 282 5.1E-32 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 SMART SM00382 350 536 2.7E-15 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 PANTHER PTHR24221:SF138 5 557 3.2E-130 T 09-11-2016 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 Gene3D G3DSA:3.40.50.300 323 553 8.1E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 SUPERFAMILY SSF90123 3 310 1.24E-51 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS16470 98bccb5cd091cdc77fcb3dbeb22f3d69 559 SUPERFAMILY SSF52540 319 558 5.03E-68 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 SUPERFAMILY SSF55136 131 285 3.4E-25 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 9.4E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 9.4E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 PANTHER PTHR11019:SF56 3 112 2.8E-48 T 09-11-2016 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 SMART SM00871 128 283 1.3E-26 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 Pfam PF12833 Helix-turn-helix domain 27 105 1.3E-19 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 SUPERFAMILY SSF46689 7 56 3.49E-7 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 SMART SM00342 21 104 4.3E-24 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 Gene3D G3DSA:1.10.10.60 58 118 1.7E-19 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 Pfam PF14526 Integron-associated effector binding protein 131 282 5.5E-24 T 09-11-2016 IPR029441 Integron-associated effector binding protein CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 PANTHER PTHR11019 3 112 2.8E-48 T 09-11-2016 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 SUPERFAMILY SSF46689 57 108 3.54E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 Gene3D G3DSA:1.10.10.60 3 57 2.7E-16 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17300 e66370309c9170ee4027d51073b5bf76 285 Gene3D G3DSA:3.20.80.10 126 284 8.3E-28 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 Gene3D G3DSA:3.80.30.20 300 558 7.0E-37 T 09-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 7 565 2.0E-273 T 09-11-2016 IPR022946 Uncharacterised protein family UPF0313 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 Pfam PF11842 Domain of unknown function (DUF3362) 519 638 2.0E-36 T 09-11-2016 IPR024560 Uncharacterised protein family UPF0313, C-terminal CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 Pfam PF08497 Radical SAM N-terminal 7 303 9.5E-137 T 09-11-2016 IPR013704 Uncharacterised protein family UPF0313, N-terminal CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 6 647 45.305 T 09-11-2016 IPR022946 Uncharacterised protein family UPF0313 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 PANTHER PTHR32331 2 646 0.0 T 09-11-2016 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 Pfam PF04055 Radical SAM superfamily 305 503 1.4E-14 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 SUPERFAMILY SSF102114 298 366 3.34E-14 T 09-11-2016 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 SUPERFAMILY SSF102114 396 548 3.34E-14 T 09-11-2016 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 PANTHER PTHR32331:SF0 2 646 0.0 T 09-11-2016 CLOSPO_RS13695 3915f5919ffc3f24e968985e85b58c4a 647 SMART SM00729 300 551 1.4E-11 T 09-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 383 2.8E-98 T 09-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 PANTHER PTHR30244 5 390 2.5E-167 T 09-11-2016 CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 Gene3D G3DSA:3.90.1150.10 261 389 5.8E-37 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 PIRSF PIRSF000390 1 391 5.4E-96 T 09-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 Gene3D G3DSA:3.40.640.10 4 260 1.1E-77 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 PANTHER PTHR30244:SF3 5 390 2.5E-167 T 09-11-2016 CLOSPO_RS17565 3413d132b036de1f5010551f59072e5a 392 SUPERFAMILY SSF53383 4 389 4.66E-101 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS13175 e924aeb61b6e0df43e9e33c588f11fb8 157 Gene3D G3DSA:2.70.70.10 6 152 4.1E-53 T 09-11-2016 CLOSPO_RS13175 e924aeb61b6e0df43e9e33c588f11fb8 157 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 9 131 3.0E-46 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13175 e924aeb61b6e0df43e9e33c588f11fb8 157 PANTHER PTHR30175 1 106 1.3E-39 T 09-11-2016 CLOSPO_RS13175 e924aeb61b6e0df43e9e33c588f11fb8 157 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 10 131 1.8E-41 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13175 e924aeb61b6e0df43e9e33c588f11fb8 157 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 73 85 - T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13175 e924aeb61b6e0df43e9e33c588f11fb8 157 SUPERFAMILY SSF51261 3 150 4.88E-50 T 09-11-2016 IPR011055 Duplicated hybrid motif CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 SUPERFAMILY SSF56784 42 283 2.12E-49 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 206 218 2.5E-12 T 09-11-2016 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 126 136 2.5E-12 T 09-11-2016 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 182 201 2.5E-12 T 09-11-2016 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 Pfam PF00702 haloacid dehalogenase-like hydrolase 17 196 3.1E-25 T 09-11-2016 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 PANTHER PTHR24093:SF210 1 283 1.9E-135 T 09-11-2016 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 Gene3D G3DSA:3.40.50.1000 104 252 2.3E-43 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 Gene3D G3DSA:3.40.1110.10 2 103 1.3E-12 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 22 262 1.2E-37 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS03505 498e007b3e9dad5089321b56de8cf140 283 PANTHER PTHR24093 1 283 1.9E-135 T 09-11-2016 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 PIRSF PIRSF000111 1 862 0.0 T 09-11-2016 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 PANTHER PTHR11496 358 862 0.0 T 09-11-2016 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Pfam PF00171 Aldehyde dehydrogenase family 5 398 5.1E-23 T 09-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 SUPERFAMILY SSF53720 6 451 7.72E-79 T 09-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 PANTHER PTHR11496:SF79 358 862 0.0 T 09-11-2016 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Gene3D G3DSA:1.20.1090.10 642 859 6.6E-73 T 09-11-2016 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 718 738 - T 09-11-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Gene3D G3DSA:3.40.309.10 224 271 8.4E-29 T 09-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Gene3D G3DSA:3.40.309.10 307 402 8.4E-29 T 09-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 SUPERFAMILY SSF56796 446 859 4.32E-126 T 09-11-2016 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 630 658 - T 09-11-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Pfam PF00465 Iron-containing alcohol dehydrogenase 455 846 6.0E-117 T 09-11-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Gene3D G3DSA:3.40.605.10 4 223 5.4E-21 T 09-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS12950 5bebbb1701c57ca2c23e8ab583e18ce8 862 Gene3D G3DSA:3.40.50.1970 448 641 1.7E-63 T 09-11-2016 CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 Gene3D G3DSA:3.40.50.300 3 231 7.3E-78 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 Pfam PF00005 ABC transporter 19 162 2.2E-34 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 PANTHER PTHR24220:SF305 5 307 1.6E-117 T 09-11-2016 CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 SUPERFAMILY SSF52540 3 227 1.2E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 PANTHER PTHR24220 5 307 1.6E-117 T 09-11-2016 CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 SMART SM00382 28 211 5.6E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS15785 0d4e76832b0cc9e254339fe136ffbd5e 310 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 Gene3D G3DSA:3.90.1200.10 101 329 3.0E-59 T 09-11-2016 CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 Pfam PF01633 Choline/ethanolamine kinase 120 250 2.0E-9 T 09-11-2016 CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 SUPERFAMILY SSF56112 18 334 1.52E-47 T 09-11-2016 IPR011009 Protein kinase-like domain CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 26 332 1.1E-94 T 09-11-2016 IPR014255 Spore coat protein CotS CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 PANTHER PTHR39179 1 336 5.7E-130 T 09-11-2016 CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 Gene3D G3DSA:3.30.200.20 8 100 1.9E-14 T 09-11-2016 CLOSPO_RS14165 ace6e7997571793112ccf86a2ed6e140 337 PANTHER PTHR39179:SF1 1 336 5.7E-130 T 09-11-2016 CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 Gene3D G3DSA:3.40.50.620 1 95 6.5E-39 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 SUPERFAMILY SSF52374 1 94 7.24E-33 T 09-11-2016 CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 Pfam PF00579 tRNA synthetases class I (W and Y) 1 95 1.4E-30 T 09-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 PANTHER PTHR10055:SF10 1 94 6.3E-55 T 09-11-2016 CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 90 95 1.1E-11 T 09-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 37 58 1.1E-11 T 09-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 CLOSPO_RS07910 849a807a9feafa5901ba80eca410bd29 95 PANTHER PTHR10055 1 94 6.3E-55 T 09-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Pfam PF00581 Rhodanese-like domain 463 542 8.2E-10 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 432 2.2E-8 T 09-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PANTHER PTHR22912:SF140 1 442 4.7E-195 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Gene3D G3DSA:3.40.250.10 441 545 2.4E-24 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SUPERFAMILY SSF64307 572 644 4.32E-19 T 09-11-2016 IPR001455 TusA-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Gene3D G3DSA:3.50.50.60 1 109 4.4E-21 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Gene3D G3DSA:3.50.50.60 110 318 2.4E-57 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SUPERFAMILY SSF75169 759 810 1.16E-20 T 09-11-2016 IPR027396 DsrEFH-like CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SUPERFAMILY SSF75169 666 709 1.16E-20 T 09-11-2016 IPR027396 DsrEFH-like CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Pfam PF13686 DsrE/DsrF/DrsH-like family 664 816 2.8E-64 T 09-11-2016 IPR032836 DsrE/DsrF/DrsH-like family CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SMART SM00450 454 548 1.1E-11 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PANTHER PTHR22912 1 442 4.7E-195 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 576 600 - T 09-11-2016 IPR001455 TusA-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SUPERFAMILY SSF55424 325 446 1.72E-28 T 09-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Pfam PF01206 Sulfurtransferase TusA 575 643 4.4E-19 T 09-11-2016 IPR001455 TusA-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SUPERFAMILY SSF52821 436 543 5.5E-24 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Gene3D G3DSA:3.30.110.40 574 644 1.2E-26 T 09-11-2016 IPR001455 TusA-like domain CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 309 6.3E-63 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 SUPERFAMILY SSF51905 1 318 9.36E-45 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 6.4E-16 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 6.4E-16 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 6.4E-16 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.4E-16 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.7E-28 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.7E-28 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 3.7E-28 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 3.7E-28 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.7E-28 T 09-11-2016 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Gene3D G3DSA:3.30.390.30 338 440 5.2E-38 T 09-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOSPO_RS13800 8c494aa20f0ed2cf337d13ad2b8fd5dd 817 Gene3D G3DSA:3.40.1260.10 659 817 2.9E-58 T 09-11-2016 IPR027396 DsrEFH-like CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 SUPERFAMILY SSF81336 72 219 4.71E-29 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 Gene3D G3DSA:1.20.120.220 73 221 1.4E-32 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 PANTHER PTHR11410 6 226 8.9E-41 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 226 11.999 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 PRINTS PR00123 ATP synthase A subunit signature 155 177 3.9E-14 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 PRINTS PR00123 ATP synthase A subunit signature 207 222 3.9E-14 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 PRINTS PR00123 ATP synthase A subunit signature 80 96 3.9E-14 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 PRINTS PR00123 ATP synthase A subunit signature 139 154 3.9E-14 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 ProSitePatterns PS00449 ATP synthase a subunit signature. 158 167 - T 09-11-2016 IPR023011 ATPase, F0 complex, subunit A, active site CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 PANTHER PTHR11410:SF7 6 226 8.9E-41 T 09-11-2016 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 Pfam PF00119 ATP synthase A chain 24 219 1.2E-45 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13975 fc7c0591806241dc48b6d70ad415fd36 226 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 20 219 1.0E-30 T 09-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 CLOSPO_RS13205 373574ccc73c08cee4680273971c878b 201 SUPERFAMILY SSF52833 1 196 1.31E-35 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS13205 373574ccc73c08cee4680273971c878b 201 Gene3D G3DSA:3.40.30.10 2 195 1.8E-42 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS13205 373574ccc73c08cee4680273971c878b 201 PANTHER PTHR13887:SF10 1 200 1.4E-130 T 09-11-2016 CLOSPO_RS13205 373574ccc73c08cee4680273971c878b 201 PANTHER PTHR13887 1 200 1.4E-130 T 09-11-2016 CLOSPO_RS13205 373574ccc73c08cee4680273971c878b 201 Pfam PF01323 DSBA-like thioredoxin domain 5 193 1.9E-35 T 09-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 Gene3D G3DSA:1.10.287.950 334 551 2.2E-42 T 09-11-2016 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 397 593 7.4E-33 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 SMART SM00304 238 290 1.9E-4 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 Pfam PF00672 HAMP domain 223 286 2.5E-7 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 PANTHER PTHR32089 22 596 3.0E-70 T 09-11-2016 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 SMART SM00283 305 594 1.9E-29 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 SUPERFAMILY SSF58104 258 292 2.88E-58 T 09-11-2016 CLOSPO_RS18405 c2b5da30370349bf6338f863b41e191f 596 SUPERFAMILY SSF58104 325 593 2.88E-58 T 09-11-2016 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 PANTHER PTHR33164 34 152 3.6E-22 T 09-11-2016 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 Gene3D G3DSA:1.10.10.10 8 145 4.2E-35 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 Pfam PF01047 MarR family 35 93 6.2E-11 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 SUPERFAMILY SSF46785 11 144 1.51E-27 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 5.0E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 5.0E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 5.0E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 5.0E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14820 06549f9cc9bd073401342ad16c1af4d2 158 SMART SM00347 28 128 1.3E-16 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 330 5.8E-143 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 Gene3D G3DSA:3.90.640.10 182 253 2.1E-32 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 Pfam PF06723 MreB/Mbl protein 7 330 4.7E-150 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PANTHER PTHR19375 3 327 2.4E-172 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PANTHER PTHR19375:SF185 3 327 2.4E-172 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 SUPERFAMILY SSF53067 7 141 3.11E-42 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 SUPERFAMILY SSF53067 144 328 5.44E-49 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 Gene3D G3DSA:3.30.420.40 258 312 1.2E-31 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 Gene3D G3DSA:3.30.420.40 155 181 1.2E-31 T 09-11-2016 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 1.2E-57 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 1.2E-57 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 1.2E-57 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 1.2E-57 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 1.2E-57 T 09-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CLOSPO_RS13910 163f63848ec42fc8cd221870298a11f1 342 Gene3D G3DSA:3.30.420.40 6 154 9.7E-48 T 09-11-2016 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 257 1.5E-106 T 09-11-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 Pfam PF00809 Pterin binding enzyme 1 243 4.2E-91 T 09-11-2016 IPR000489 Pterin-binding domain GO:0042558 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 PANTHER PTHR20941 1 261 1.2E-124 T 09-11-2016 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 Gene3D G3DSA:3.20.20.20 1 260 6.3E-109 T 09-11-2016 IPR000489 Pterin-binding domain GO:0042558 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 PANTHER PTHR20941:SF1 1 261 1.2E-124 T 09-11-2016 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 09-11-2016 IPR000489 Pterin-binding domain GO:0042558 CLOSPO_RS17545 b3b202ff131a760b243496ffa0a664dc 261 SUPERFAMILY SSF51717 1 260 1.57E-98 T 09-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 CLOSPO_RS13330 425b340acaf788318ff256fcc703295b 188 Pfam PF00578 AhpC/TSA family 51 168 3.9E-25 T 09-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 CLOSPO_RS13330 425b340acaf788318ff256fcc703295b 188 Gene3D G3DSA:3.40.30.10 12 188 9.8E-44 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS13330 425b340acaf788318ff256fcc703295b 188 PANTHER PTHR10681 6 174 2.3E-49 T 09-11-2016 CLOSPO_RS13330 425b340acaf788318ff256fcc703295b 188 SUPERFAMILY SSF52833 50 186 7.73E-36 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS13330 425b340acaf788318ff256fcc703295b 188 PANTHER PTHR10681:SF125 6 174 2.3E-49 T 09-11-2016 CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 PANTHER PTHR39156 1 181 3.3E-88 T 09-11-2016 CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 173 7.2E-46 T 09-11-2016 IPR004466 Ribonuclease M5 GO:0043822 CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 Pfam PF01751 Toprim domain 4 80 3.7E-8 T 09-11-2016 IPR006171 Toprim domain CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 SUPERFAMILY SSF110455 1 114 4.71E-32 T 09-11-2016 CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 176 29.058 T 09-11-2016 IPR004466 Ribonuclease M5 GO:0043822 CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 SMART SM00493 3 76 1.2E-8 T 09-11-2016 IPR006171 Toprim domain CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 Gene3D G3DSA:3.40.1360.20 1 121 2.9E-38 T 09-11-2016 CLOSPO_RS14330 ab6b0db6f1867fb0b529a468008e81e5 181 Pfam PF13331 Domain of unknown function (DUF4093) 89 173 3.3E-27 T 09-11-2016 IPR025156 Ribonuclease M5, C-terminal domain CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Gene3D G3DSA:3.30.230.10 222 394 1.6E-74 T 09-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 SMART SM00387 34 178 6.4E-27 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 177 2.9E-23 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Gene3D G3DSA:3.30.565.10 9 220 7.4E-91 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PANTHER PTHR10169:SF44 9 637 0.0 T 09-11-2016 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 SUPERFAMILY SSF54211 223 393 1.19E-61 T 09-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 472 481 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 198 211 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 362 376 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 314 330 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 9 19 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 590 602 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 222 244 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 376 396 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 606 622 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR01159 DNA gyrase subunit B signature 183 198 4.0E-79 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 637 94.946 T 09-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 SUPERFAMILY SSF55874 9 220 1.02E-76 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 526 538 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 38 53 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 422 436 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 116 130 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 73 86 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 488 504 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 506 523 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 569 585 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PRINTS PR00418 DNA topoisomerase II family signature 270 283 9.4E-73 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 PANTHER PTHR10169 9 637 0.0 T 09-11-2016 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 637 0.0 T 09-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Pfam PF00204 DNA gyrase B 223 392 7.0E-63 T 09-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Gene3D G3DSA:3.40.50.670 406 619 4.1E-100 T 09-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Pfam PF01751 Toprim domain 421 532 6.3E-18 T 09-11-2016 IPR006171 Toprim domain CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 SUPERFAMILY SSF56719 396 631 2.62E-93 T 09-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 ProSitePatterns PS00177 DNA topoisomerase II signature. 424 432 - T 09-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 SMART SM00433 38 630 0.0 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14520 72964863905f7883fbd424e9c43ddbd4 637 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 565 626 2.6E-31 T 09-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 Pfam PF04560 RNA polymerase Rpb2, domain 7 365 439 6.6E-28 T 09-11-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 Gene3D G3DSA:2.40.50.100 1 45 1.1E-20 T 09-11-2016 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 Gene3D G3DSA:2.40.270.10 213 341 1.5E-77 T 09-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 Gene3D G3DSA:2.40.270.10 46 73 1.5E-77 T 09-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 Gene3D G3DSA:2.40.50.150 80 212 3.2E-61 T 09-11-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 PANTHER PTHR20856:SF20 5 445 0.0 T 09-11-2016 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 SUPERFAMILY SSF64484 3 443 7.32E-205 T 09-11-2016 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 PANTHER PTHR20856 5 445 0.0 T 09-11-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 Pfam PF00562 RNA polymerase Rpb2, domain 6 3 363 1.0E-162 T 09-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS07065 b60ae9af71a87b07e5d436e40e274de4 445 ProSitePatterns PS01166 RNA polymerases beta chain signature. 216 228 - T 09-11-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 413 1.5E-19 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 1.5E-19 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 309 338 1.5E-19 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 1.5E-19 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 Gene3D G3DSA:1.10.287.950 303 520 4.2E-49 T 09-11-2016 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 Pfam PF00672 HAMP domain 188 255 2.2E-8 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 SMART SM00283 288 563 4.8E-68 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 PANTHER PTHR32089 179 565 1.5E-88 T 09-11-2016 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 SMART SM00304 202 259 4.0E-6 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 SUPERFAMILY SSF58104 294 563 2.22E-68 T 09-11-2016 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 SUPERFAMILY SSF58104 227 261 2.22E-68 T 09-11-2016 CLOSPO_RS16145 8ad887ee66549fc72942f02e46e804db 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 538 3.4E-47 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 SUPERFAMILY SSF103190 48 186 9.68E-7 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 450 562 9.5E-28 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Pfam PF00672 HAMP domain 298 362 4.3E-8 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 SMART SM00283 391 674 6.3E-24 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Pfam PF02743 Cache domain 45 279 1.4E-19 T 09-11-2016 IPR033479 Double Cache domain 1 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 SUPERFAMILY SSF58104 404 673 6.8E-53 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 SUPERFAMILY SSF58104 337 371 6.8E-53 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Gene3D G3DSA:3.30.450.20 101 168 6.7E-11 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 PANTHER PTHR32089:SF1 9 675 6.9E-165 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Gene3D G3DSA:1.10.287.950 602 649 8.4E-43 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Gene3D G3DSA:1.10.287.950 422 565 8.4E-43 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Gene3D G3DSA:1.10.287.950 352 421 7.1E-5 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 Gene3D G3DSA:3.30.450.20 169 294 1.7E-22 T 09-11-2016 CLOSPO_RS15890 88dcf71c5d02bd79fc47769c916276c8 676 PANTHER PTHR32089 9 675 6.9E-165 T 09-11-2016 CLOSPO_RS15995 ec3b0b61549898fedb6c6afce10b3e98 169 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 3.1E-9 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS15995 ec3b0b61549898fedb6c6afce10b3e98 169 Gene3D G3DSA:2.160.10.10 2 167 4.0E-48 T 09-11-2016 CLOSPO_RS15995 ec3b0b61549898fedb6c6afce10b3e98 169 SUPERFAMILY SSF51161 2 164 6.93E-45 T 09-11-2016 IPR011004 Trimeric LpxA-like CLOSPO_RS15995 ec3b0b61549898fedb6c6afce10b3e98 169 PANTHER PTHR13061 1 169 3.1E-67 T 09-11-2016 CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 SUPERFAMILY SSF53383 26 430 1.14E-84 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 Gene3D G3DSA:3.40.640.10 52 289 3.9E-58 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 Gene3D G3DSA:3.90.1150.10 290 427 7.8E-17 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 PANTHER PTHR11601 28 433 7.8E-142 T 09-11-2016 CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 Pfam PF00266 Aminotransferase class-V 31 420 3.9E-87 T 09-11-2016 IPR000192 Aminotransferase class V domain CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 PANTHER PTHR11601:SF17 28 433 7.8E-142 T 09-11-2016 CLOSPO_RS12855 49b3023d0f43b1e89b742339309d4f49 440 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 223 242 - T 09-11-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 Pfam PF13847 Methyltransferase domain 32 138 1.4E-13 T 09-11-2016 IPR025714 Methyltransferase domain CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 PANTHER PTHR14741 4 184 8.0E-52 T 09-11-2016 CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 PANTHER PTHR14741:SF34 4 184 8.0E-52 T 09-11-2016 CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 Gene3D G3DSA:3.40.50.150 7 187 2.8E-29 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 SUPERFAMILY SSF53335 11 162 1.22E-30 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 15 138 6.2E-38 T 09-11-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18105 137a7cef8377348ddd025a1a6c36bd47 193 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 37 66 - T 09-11-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CLOSPO_RS16700 002570f79db079c4953d3dff02981070 286 SUPERFAMILY SSF53098 1 190 1.68E-27 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS16700 002570f79db079c4953d3dff02981070 286 PANTHER PTHR23044 3 187 5.9E-21 T 09-11-2016 CLOSPO_RS16700 002570f79db079c4953d3dff02981070 286 PANTHER PTHR23044:SF5 3 187 5.9E-21 T 09-11-2016 CLOSPO_RS16700 002570f79db079c4953d3dff02981070 286 SMART SM00479 2 193 9.5E-7 T 09-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOSPO_RS16700 002570f79db079c4953d3dff02981070 286 Pfam PF00929 Exonuclease 34 184 3.3E-14 T 09-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOSPO_RS16700 002570f79db079c4953d3dff02981070 286 Gene3D G3DSA:3.30.420.10 1 193 6.9E-40 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Gene3D G3DSA:3.30.1360.120 4 55 1.3E-52 T 09-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Gene3D G3DSA:3.30.1360.120 146 238 1.3E-52 T 09-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 SUPERFAMILY SSF101790 276 366 3.27E-25 T 09-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Pfam PF01571 Aminomethyltransferase folate-binding domain 13 261 5.9E-98 T 09-11-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 PIRSF PIRSF006487 1 370 7.3E-110 T 09-11-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 PANTHER PTHR13847 1 357 2.2E-72 T 09-11-2016 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 359 2.2E-28 T 09-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 SUPERFAMILY SSF103025 3 284 1.12E-102 T 09-11-2016 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Gene3D G3DSA:3.30.70.1400 56 138 9.7E-34 T 09-11-2016 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 PANTHER PTHR13847:SF5 1 357 2.2E-72 T 09-11-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Gene3D G3DSA:2.40.30.110 285 358 2.9E-26 T 09-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 365 46.574 T 09-11-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOSPO_RS16945 dfdd6ceb4ec4b74558eb77503eff984d 370 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 364 1.1E-131 T 09-11-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 Pfam PF13411 MerR HTH family regulatory protein 3 70 5.1E-15 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 Gene3D G3DSA:1.10.1660.10 3 109 4.0E-25 T 09-11-2016 CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 Pfam PF07739 TipAS antibiotic-recognition domain 293 381 6.3E-17 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 Pfam PF07739 TipAS antibiotic-recognition domain 160 288 3.3E-23 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 Gene3D G3DSA:1.10.490.50 297 384 3.4E-6 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 SUPERFAMILY SSF46955 3 104 2.93E-25 T 09-11-2016 IPR009061 Putative DNA-binding domain CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 SMART SM00422 3 71 2.0E-23 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 SUPERFAMILY SSF89082 297 382 3.14E-7 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 PANTHER PTHR30204 3 197 9.7E-31 T 09-11-2016 CLOSPO_RS17725 1d09fb74c5b6af03dec38ed29ab13cd1 387 PANTHER PTHR30204:SF27 3 197 9.7E-31 T 09-11-2016 CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 PANTHER PTHR33992 2 107 4.8E-34 T 09-11-2016 CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 SUPERFAMILY SSF54211 2 110 1.47E-29 T 09-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 110 5.7E-26 T 09-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 6 106 4.0E-21 T 09-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 Gene3D G3DSA:3.30.230.10 2 109 3.9E-35 T 09-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 110 17.1 T 09-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOSPO_RS14555 ba1a5a8f05084e51324513ba7d8f915e 111 Pfam PF00825 Ribonuclease P 2 107 7.0E-31 T 09-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 Gene3D G3DSA:3.40.50.150 103 377 2.7E-95 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 PANTHER PTHR10108:SF743 309 392 2.2E-143 T 09-11-2016 CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 PANTHER PTHR10108:SF743 103 292 2.2E-143 T 09-11-2016 CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 PIRSF PIRSF003085 2 392 4.5E-125 T 09-11-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 PANTHER PTHR10108 309 392 2.2E-143 T 09-11-2016 CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 Pfam PF02353 Mycolic acid cyclopropane synthetase 105 373 7.7E-99 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 SUPERFAMILY SSF53335 3 331 2.46E-79 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16450 982066107c3552789e0a640afb6f986f 392 PANTHER PTHR10108 103 292 2.2E-143 T 09-11-2016 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 Gene3D G3DSA:3.40.1450.10 78 308 6.5E-100 T 09-11-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 SUPERFAMILY SSF53649 3 77 5.89E-76 T 09-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 SUPERFAMILY SSF53649 312 508 5.89E-76 T 09-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 4 508 5.5E-228 T 09-11-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 PANTHER PTHR31637 3 509 4.6E-284 T 09-11-2016 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 Gene3D G3DSA:3.40.720.10 312 508 4.0E-92 T 09-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 Gene3D G3DSA:3.40.720.10 3 77 4.0E-92 T 09-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 295 1.0E-89 T 09-11-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 509 51.418 T 09-11-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 PANTHER PTHR31637:SF0 3 509 4.6E-284 T 09-11-2016 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 SUPERFAMILY SSF64158 77 307 4.45E-88 T 09-11-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 Pfam PF01676 Metalloenzyme superfamily 4 497 1.5E-80 T 09-11-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CLOSPO_RS13560 7a471c17b531afa0b7438b1909d151da 509 PIRSF PIRSF001492 1 509 6.4E-215 T 09-11-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS14130 681f9679bd84a5cd36882a23a4025790 266 PANTHER PTHR36175 5 266 8.4E-92 T 09-11-2016 CLOSPO_RS14130 681f9679bd84a5cd36882a23a4025790 266 PIRSF PIRSF032067 2 264 1.1E-63 T 09-11-2016 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 CLOSPO_RS14130 681f9679bd84a5cd36882a23a4025790 266 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 9 258 6.6E-106 T 09-11-2016 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 CLOSPO_RS14130 681f9679bd84a5cd36882a23a4025790 266 Pfam PF03575 Peptidase family S51 9 209 6.7E-24 T 09-11-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CLOSPO_RS14130 681f9679bd84a5cd36882a23a4025790 266 SUPERFAMILY SSF52317 9 223 3.57E-23 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS14130 681f9679bd84a5cd36882a23a4025790 266 Gene3D G3DSA:3.40.50.880 10 227 7.4E-32 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 PANTHER PTHR10210 1 318 2.6E-185 T 09-11-2016 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 318 7.7E-127 T 09-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 Gene3D G3DSA:3.40.50.2020 6 164 4.2E-77 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 Pfam PF14572 Phosphoribosyl synthetase-associated domain 209 317 6.9E-22 T 09-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 132 147 - T 09-11-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 SMART SM01400 8 124 1.5E-80 T 09-11-2016 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 SUPERFAMILY SSF53271 73 309 5.59E-68 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 Gene3D G3DSA:3.40.50.2020 165 289 4.5E-54 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 PANTHER PTHR10210:SF41 1 318 2.6E-185 T 09-11-2016 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 2.6E-51 T 09-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 CLOSPO_RS15145 8271a7e9b82d26d4c4ec16a27b2a9921 319 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 8 318 51.343 T 09-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 SMART SM00271 1 62 3.6E-22 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 SUPERFAMILY SSF48452 93 154 4.75E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 Gene3D G3DSA:1.10.287.110 2 84 3.1E-22 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 PRINTS PR00625 DnaJ domain signature 22 37 4.1E-16 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 PRINTS PR00625 DnaJ domain signature 42 62 4.1E-16 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 PRINTS PR00625 DnaJ domain signature 4 22 4.1E-16 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 Gene3D G3DSA:1.25.40.10 105 148 5.2E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 Pfam PF00226 DnaJ domain 2 67 2.8E-19 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 SUPERFAMILY SSF46565 1 74 1.7E-21 T 09-11-2016 IPR001623 DnaJ domain CLOSPO_RS13760 e84aa0d1b08d25b9dbbf874cfb6aed28 199 PANTHER PTHR24078 1 57 1.2E-17 T 09-11-2016 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 Pfam PF00512 His Kinase A (phospho-acceptor) domain 89 148 3.5E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 PANTHER PTHR24423 1 294 1.7E-41 T 09-11-2016 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 SUPERFAMILY SSF47384 78 149 6.08E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 Gene3D G3DSA:3.30.565.10 152 291 3.4E-26 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 SMART SM00388 86 149 2.5E-12 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 PANTHER PTHR24423:SF547 1 294 1.7E-41 T 09-11-2016 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 PRINTS PR00344 Bacterial sensor protein C-terminal signature 263 281 3.2E-6 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 PRINTS PR00344 Bacterial sensor protein C-terminal signature 248 258 3.2E-6 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 SUPERFAMILY SSF55874 138 284 2.36E-23 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 SMART SM00387 195 302 1.5E-14 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 Gene3D G3DSA:1.10.287.130 85 144 3.6E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13430 2c93336122bd5f85aeea5b87bd878366 302 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 197 285 3.7E-14 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 Gene3D G3DSA:3.60.110.10 9 286 5.7E-43 T 09-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 Pfam PF00795 Carbon-nitrogen hydrolase 19 272 1.1E-12 T 09-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 TIGRFAM TIGR00552 nadE: NAD+ synthetase 341 507 3.6E-27 T 09-11-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 Gene3D G3DSA:3.40.50.620 317 615 1.1E-66 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 SUPERFAMILY SSF52402 316 618 3.31E-74 T 09-11-2016 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 PIRSF PIRSF006630 5 638 1.7E-170 T 09-11-2016 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|UniPathway: UPA00253 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 Pfam PF02540 NAD synthase 339 574 1.7E-31 T 09-11-2016 IPR022310 NAD/GMP synthase CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 PANTHER PTHR23090 5 637 6.4E-208 T 09-11-2016 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 SUPERFAMILY SSF56317 9 286 1.7E-40 T 09-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CLOSPO_RS16030 192d6e16d82b9677dfe59eaf323bdb12 638 PANTHER PTHR23090:SF9 5 637 6.4E-208 T 09-11-2016 CLOSPO_RS15850 67a85a05090227928254a5dc8c72e8a8 87 Pfam PF13031 Protein of unknown function (DUF3892) 12 79 1.3E-11 T 09-11-2016 IPR024997 Protein of unknown function DUF3892 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 SUPERFAMILY SSF116878 128 227 2.09E-49 T 09-11-2016 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 SUPERFAMILY SSF116878 386 461 2.09E-49 T 09-11-2016 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Gene3D G3DSA:3.40.50.300 200 254 1.6E-6 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 461 1.1E-129 T 09-11-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Gene3D G3DSA:3.30.1360.120 1 128 1.0E-43 T 09-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Gene3D G3DSA:1.20.120.430 395 461 6.4E-54 T 09-11-2016 IPR027368 tRNA modification GTPase MnmE domain 2 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Gene3D G3DSA:1.20.120.430 129 189 6.4E-54 T 09-11-2016 IPR027368 tRNA modification GTPase MnmE domain 2 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Gene3D G3DSA:1.20.120.430 255 278 6.4E-54 T 09-11-2016 IPR027368 tRNA modification GTPase MnmE domain 2 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 461 35.487 T 09-11-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 PANTHER PTHR11649 8 461 1.3E-163 T 09-11-2016 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Pfam PF12631 MnmE helical domain 130 458 1.5E-59 T 09-11-2016 IPR025867 MnmE, helical domain CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 SUPERFAMILY SSF52540 195 378 5.66E-44 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 SUPERFAMILY SSF52540 81 159 5.66E-44 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 PANTHER PTHR11649:SF56 8 461 1.3E-163 T 09-11-2016 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Gene3D G3DSA:3.40.50.300 293 394 5.9E-15 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Pfam PF01926 50S ribosome-binding GTPase 226 338 3.8E-28 T 09-11-2016 IPR006073 GTP binding domain GO:0005525 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 377 1.6E-27 T 09-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 CLOSPO_RS14575 bbd3d08ef9cb6e8cc1042463cf62968b 461 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 127 2.7E-40 T 09-11-2016 IPR018948 GTP-binding protein TrmE, N-terminal CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 Pfam PF09383 NIL domain 248 317 2.2E-13 T 09-11-2016 IPR018449 NIL domain CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 Pfam PF00005 ABC transporter 17 165 6.2E-38 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 PANTHER PTHR24220:SF549 3 251 2.9E-143 T 09-11-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 Gene3D G3DSA:3.40.50.300 1 229 1.5E-82 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 PANTHER PTHR24220 3 251 2.9E-143 T 09-11-2016 CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 SMART SM00930 245 318 1.6E-17 T 09-11-2016 IPR018449 NIL domain CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 SMART SM00382 26 214 4.8E-16 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 SUPERFAMILY SSF55021 236 317 3.09E-15 T 09-11-2016 CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 Gene3D G3DSA:3.30.70.260 230 317 7.4E-16 T 09-11-2016 CLOSPO_RS18930 c86175ddf0c865e0c62f940801c8c1a9 318 SUPERFAMILY SSF52540 1 233 5.97E-79 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 PANTHER PTHR24220 6 246 3.1E-111 T 09-11-2016 CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 PANTHER PTHR24220:SF594 6 246 3.1E-111 T 09-11-2016 CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 SUPERFAMILY SSF52540 4 224 7.66E-71 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 SMART SM00382 33 221 3.6E-14 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 Pfam PF00005 ABC transporter 24 172 4.5E-33 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13410 6f7ebbe452f04040ce59a8fc47c21d6d 254 Gene3D G3DSA:3.40.50.300 2 223 1.1E-70 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 SUPERFAMILY SSF52540 145 388 5.68E-63 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 Gene3D G3DSA:3.40.50.300 149 329 3.7E-59 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 576 5.0E-166 T 09-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 SUPERFAMILY SSF140990 403 575 2.22E-51 T 09-11-2016 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 PANTHER PTHR23076 13 574 4.6E-198 T 09-11-2016 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 Pfam PF01434 Peptidase family M41 382 576 1.2E-53 T 09-11-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 576 30.18 T 09-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 187 319 2.9E-42 T 09-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 ProSitePatterns PS00674 AAA-protein family signature. 290 308 - T 09-11-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 SMART SM00382 183 322 3.5E-22 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 PANTHER PTHR23076:SF10 13 574 4.6E-198 T 09-11-2016 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 Gene3D G3DSA:1.10.8.60 330 393 2.7E-17 T 09-11-2016 CLOSPO_RS12650 5d8d5fe165338f7daa31868ebfce3449 576 Pfam PF06480 FtsH Extracellular 12 91 1.4E-6 T 09-11-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 CLOSPO_RS17485 b8ad6ccc7e0cca3252dc4d8deb2792b8 78 SUPERFAMILY SSF50037 8 76 2.41E-18 T 09-11-2016 IPR008988 Transcriptional repressor, C-terminal CLOSPO_RS17485 b8ad6ccc7e0cca3252dc4d8deb2792b8 78 PANTHER PTHR33238 5 77 5.8E-21 T 09-11-2016 CLOSPO_RS17485 b8ad6ccc7e0cca3252dc4d8deb2792b8 78 SMART SM00899 5 77 1.0E-18 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS17485 b8ad6ccc7e0cca3252dc4d8deb2792b8 78 Pfam PF04023 FeoA domain 6 76 3.3E-15 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 3.5E-7 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 3.5E-7 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 495 2.7E-17 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 SUPERFAMILY SSF55874 335 498 1.57E-30 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PANTHER PTHR24423:SF511 212 504 8.0E-191 T 09-11-2016 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 SMART SM00387 391 502 1.5E-27 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PANTHER PTHR24423:SF511 92 165 8.0E-191 T 09-11-2016 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PANTHER PTHR24423:SF511 4 31 8.0E-191 T 09-11-2016 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 SMART SM00304 218 270 8.2E-5 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 Pfam PF00672 HAMP domain 201 266 5.4E-9 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PANTHER PTHR24423 92 165 8.0E-191 T 09-11-2016 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PANTHER PTHR24423 4 31 8.0E-191 T 09-11-2016 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 PANTHER PTHR24423 212 504 8.0E-191 T 09-11-2016 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 SMART SM00388 278 345 4.5E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 SUPERFAMILY SSF47384 261 345 1.94E-17 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 Gene3D G3DSA:1.10.287.130 269 331 2.2E-17 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 Gene3D G3DSA:3.30.565.10 332 499 1.6E-33 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 Pfam PF00512 His Kinase A (phospho-acceptor) domain 278 340 1.3E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12835 3d97a61de64b259e66ecbc721566998e 504 SUPERFAMILY SSF158472 224 267 3.79E-6 T 09-11-2016 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 SMART SM00448 10 122 4.2E-28 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 PANTHER PTHR26402:SF501 10 209 7.7E-69 T 09-11-2016 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 Gene3D G3DSA:1.10.10.10 127 214 4.0E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 SUPERFAMILY SSF52172 10 140 1.71E-29 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 PANTHER PTHR26402 10 209 7.7E-69 T 09-11-2016 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.8E-16 T 09-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 SMART SM00421 153 210 4.5E-20 T 09-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 09-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 Pfam PF00072 Response regulator receiver domain 12 122 1.5E-24 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 SUPERFAMILY SSF46894 154 212 6.46E-17 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 Gene3D G3DSA:3.40.50.2300 8 126 3.7E-30 T 09-11-2016 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.6E-11 T 09-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.6E-11 T 09-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOSPO_RS15810 dc3f2acdb05d228776aa8db03d0e98a7 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.6E-11 T 09-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Gene3D G3DSA:1.10.1780.10 1 152 3.1E-40 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Gene3D G3DSA:1.10.8.60 786 864 1.6E-30 T 09-11-2016 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Gene3D G3DSA:3.40.50.300 558 785 1.1E-57 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 SMART SM01086 774 863 1.2E-35 T 09-11-2016 IPR019489 Clp ATPase, C-terminal CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 PANTHER PTHR11638:SF18 1 865 0.0 T 09-11-2016 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 SUPERFAMILY SSF52540 553 857 3.62E-79 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 308 7.4E-13 T 09-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 SMART SM00382 604 751 2.1E-13 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 SMART SM00382 202 348 4.3E-10 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 638 656 - T 09-11-2016 IPR028299 ClpA/B, conserved site 2 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 298 310 - T 09-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 SUPERFAMILY SSF52540 162 552 1.43E-99 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Gene3D G3DSA:1.10.8.60 347 432 2.9E-35 T 09-11-2016 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 853 1.7E-26 T 09-11-2016 IPR019489 Clp ATPase, C-terminal CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 SUPERFAMILY SSF81923 4 160 7.19E-38 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 603 768 1.5E-55 T 09-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 PANTHER PTHR11638 1 865 0.0 T 09-11-2016 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 715 729 2.6E-42 T 09-11-2016 IPR001270 ClpA/B family GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 608 626 2.6E-42 T 09-11-2016 IPR001270 ClpA/B family GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 671 2.6E-42 T 09-11-2016 IPR001270 ClpA/B family GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 682 700 2.6E-42 T 09-11-2016 IPR001270 ClpA/B family GO:0005524 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 09-11-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 149 2.3E-12 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 68 5.1E-13 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS12605 f202f98424ee43648898b141c5b46162 866 Gene3D G3DSA:3.40.50.300 163 345 2.0E-51 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 SUPERFAMILY SSF53613 7 261 2.65E-59 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 Pfam PF02110 Hydroxyethylthiazole kinase family 7 252 8.5E-84 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 Gene3D G3DSA:3.40.1190.20 5 261 1.1E-85 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 9 255 30.973 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 15 22 5.7E-32 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 160 177 5.7E-32 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 85 102 5.7E-32 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 116 130 5.7E-32 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 59 67 5.7E-32 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 28 49 5.7E-32 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PANTHER PTHR20857 5 263 2.2E-92 T 09-11-2016 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 7 253 8.7E-88 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PIRSF PIRSF000513 1 263 7.5E-88 T 09-11-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15585 b9104ce1f3181a7b5272997f726c2f25 263 PANTHER PTHR20857:SF19 5 263 2.2E-92 T 09-11-2016 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 Pfam PF00512 His Kinase A (phospho-acceptor) domain 146 211 6.9E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PANTHER PTHR24423:SF526 30 59 8.6E-148 T 09-11-2016 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 259 366 1.9E-16 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 2.0E-8 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 2.0E-8 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 2.0E-8 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 SUPERFAMILY SSF55874 202 367 3.93E-37 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 Gene3D G3DSA:3.30.565.10 214 367 3.1E-35 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PANTHER PTHR24423 30 59 8.6E-148 T 09-11-2016 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 SMART SM00388 145 212 5.0E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 Gene3D G3DSA:1.10.287.130 140 208 1.7E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 SMART SM00387 258 368 2.1E-26 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PANTHER PTHR24423 79 368 8.6E-148 T 09-11-2016 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 SUPERFAMILY SSF47384 135 212 1.59E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16420 6737e982c6aff967b10a1102554a0c9c 368 PANTHER PTHR24423:SF526 79 368 8.6E-148 T 09-11-2016 CLOSPO_RS16530 9c6812739b690a04c2d951c73681c357 157 PANTHER PTHR34071 1 156 1.1E-48 T 09-11-2016 CLOSPO_RS16530 9c6812739b690a04c2d951c73681c357 157 Gene3D G3DSA:2.30.110.10 3 155 5.3E-41 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS16530 9c6812739b690a04c2d951c73681c357 157 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 154 1.2E-21 T 09-11-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CLOSPO_RS16530 9c6812739b690a04c2d951c73681c357 157 SUPERFAMILY SSF50475 4 156 9.35E-40 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 PANTHER PTHR30175:SF1 1 229 1.1E-73 T 09-11-2016 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 Pfam PF02378 Phosphotransferase system, EIIC 97 218 1.0E-15 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 SUPERFAMILY SSF55604 1 66 6.54E-19 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 Pfam PF00367 phosphotransferase system, EIIB 1 27 1.5E-12 T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 6 23 - T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 Gene3D G3DSA:3.30.1360.60 1 65 7.5E-24 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS10450 af8c247bca86cd6e2785910258323aab 229 PANTHER PTHR30175 1 229 1.1E-73 T 09-11-2016 CLOSPO_RS15270 2d8c0e9118b2ccce0003ba3222500a83 181 SUPERFAMILY SSF53271 4 181 1.88E-58 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15270 2d8c0e9118b2ccce0003ba3222500a83 181 Gene3D G3DSA:3.40.50.2020 4 181 6.3E-83 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15270 2d8c0e9118b2ccce0003ba3222500a83 181 PANTHER PTHR22573:SF56 6 181 6.8E-82 T 09-11-2016 CLOSPO_RS15270 2d8c0e9118b2ccce0003ba3222500a83 181 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 11 175 1.9E-68 T 09-11-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 CLOSPO_RS15270 2d8c0e9118b2ccce0003ba3222500a83 181 Pfam PF00156 Phosphoribosyl transferase domain 16 162 1.6E-26 T 09-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOSPO_RS15270 2d8c0e9118b2ccce0003ba3222500a83 181 PANTHER PTHR22573 6 181 6.8E-82 T 09-11-2016 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 SUPERFAMILY SSF75620 8 351 5.1E-141 T 09-11-2016 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 Pfam PF00472 RF-1 domain 210 319 3.3E-42 T 09-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 41.603 T 09-11-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 09-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 SMART SM00937 63 177 2.2E-69 T 09-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 Pfam PF03462 PCRF domain 8 202 1.7E-78 T 09-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 353 1.2E-170 T 09-11-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 Gene3D G3DSA:3.30.160.20 209 286 1.4E-34 T 09-11-2016 IPR014720 Double-stranded RNA-binding domain CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 Gene3D G3DSA:1.20.58.410 8 92 9.0E-23 T 09-11-2016 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 PANTHER PTHR11075 1 354 4.8E-183 T 09-11-2016 CLOSPO_RS14030 46fa24980a9da6de2d1b8569690122a3 358 PANTHER PTHR11075:SF9 1 354 4.8E-183 T 09-11-2016 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Pfam PF00750 tRNA synthetases class I (R) 92 434 4.8E-96 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 563 9.3E-154 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 81 4.4E-18 T 09-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 120 131 - T 09-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 PANTHER PTHR11956 1 563 1.7E-241 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Gene3D G3DSA:3.40.50.620 105 440 2.7E-112 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Pfam PF05746 DALR anticodon binding domain 448 563 8.3E-31 T 09-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 SMART SM01016 1 82 3.6E-26 T 09-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 SUPERFAMILY SSF52374 106 442 3.44E-98 T 09-11-2016 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 PANTHER PTHR11956:SF1 1 563 1.7E-241 T 09-11-2016 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 SMART SM00836 448 563 9.5E-42 T 09-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Gene3D G3DSA:3.30.1360.70 3 99 2.1E-30 T 09-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 SUPERFAMILY SSF47323 442 563 3.01E-32 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Gene3D G3DSA:1.10.730.10 442 563 8.4E-35 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 151 164 6.9E-21 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 112 127 6.9E-21 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 127 143 6.9E-21 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 295 316 6.9E-21 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 SUPERFAMILY SSF55190 3 103 2.62E-26 T 09-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18880 dcf55fbb644b86352eb07974ca076b39 563 Hamap MF_00123 Arginine--tRNA ligase [argS]. 1 563 25.884 T 09-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 PANTHER PTHR21343 1 440 9.4E-173 T 09-11-2016 CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 238 429 9.0E-35 T 09-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 Gene3D G3DSA:3.40.50.300 77 188 1.2E-10 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 Gene3D G3DSA:3.40.50.300 1 46 4.2E-6 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 PANTHER PTHR21343:SF6 1 440 9.4E-173 T 09-11-2016 CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 179 2.5E-19 T 09-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 4 437 4.1E-124 T 09-11-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 SUPERFAMILY SSF52317 236 439 1.42E-25 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 SUPERFAMILY SSF52540 1 190 6.01E-36 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 431 38.247 T 09-11-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CLOSPO_RS18025 0bc940488c311e6e29ede429da8e5fe7 440 Gene3D G3DSA:3.40.50.880 239 438 5.3E-19 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 PIRSF PIRSF006402 2 682 2.9E-245 T 09-11-2016 IPR024705 Spermatogenesis-associated protein 20 CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 SUPERFAMILY SSF48208 187 537 5.78E-84 T 09-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 SUPERFAMILY SSF52833 8 145 3.57E-34 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 Gene3D G3DSA:3.40.30.10 26 154 1.0E-36 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 PANTHER PTHR12145 8 679 0.0 T 09-11-2016 CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 Gene3D G3DSA:1.50.10.10 185 322 2.9E-9 T 09-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 Gene3D G3DSA:1.50.10.10 384 583 4.9E-16 T 09-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 PANTHER PTHR12145:SF11 8 679 0.0 T 09-11-2016 CLOSPO_RS18815 532a6ccd9d8406e7f6f420f635fd8d15 682 Pfam PF03190 Protein of unknown function, DUF255 8 169 1.1E-77 T 09-11-2016 IPR004879 Domain of unknown function DUF255 CLOSPO_RS18570 410243410551aa9325428a03abee85b3 194 Pfam PF01965 DJ-1/PfpI family 2 177 4.9E-26 T 09-11-2016 IPR002818 DJ-1/PfpI CLOSPO_RS18570 410243410551aa9325428a03abee85b3 194 PANTHER PTHR11019 1 169 1.1E-83 T 09-11-2016 CLOSPO_RS18570 410243410551aa9325428a03abee85b3 194 Gene3D G3DSA:3.40.50.880 1 179 1.2E-41 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS18570 410243410551aa9325428a03abee85b3 194 PANTHER PTHR11019:SF125 1 169 1.1E-83 T 09-11-2016 CLOSPO_RS18570 410243410551aa9325428a03abee85b3 194 SUPERFAMILY SSF52317 1 192 7.64E-36 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS16815 c6b07707255d3cb3e07ee2e1d8d31cbc 126 PIRSF PIRSF019455 1 126 2.3E-40 T 09-11-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CLOSPO_RS16815 c6b07707255d3cb3e07ee2e1d8d31cbc 126 Gene3D G3DSA:1.10.10.10 1 80 3.8E-30 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16815 c6b07707255d3cb3e07ee2e1d8d31cbc 126 PANTHER PTHR34134:SF1 4 124 3.0E-30 T 09-11-2016 CLOSPO_RS16815 c6b07707255d3cb3e07ee2e1d8d31cbc 126 PANTHER PTHR34134 4 124 3.0E-30 T 09-11-2016 CLOSPO_RS16815 c6b07707255d3cb3e07ee2e1d8d31cbc 126 Pfam PF03965 Penicillinase repressor 7 120 2.3E-35 T 09-11-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CLOSPO_RS16815 c6b07707255d3cb3e07ee2e1d8d31cbc 126 SUPERFAMILY SSF46785 4 124 1.02E-33 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17135 1962c9aae55392a6d9d08c3d2d49a861 140 Pfam PF01381 Helix-turn-helix 8 62 8.7E-15 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17135 1962c9aae55392a6d9d08c3d2d49a861 140 SMART SM00530 6 62 7.8E-14 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17135 1962c9aae55392a6d9d08c3d2d49a861 140 SUPERFAMILY SSF47413 1 64 5.09E-16 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17135 1962c9aae55392a6d9d08c3d2d49a861 140 PANTHER PTHR10245 1 117 5.8E-16 T 09-11-2016 CLOSPO_RS17135 1962c9aae55392a6d9d08c3d2d49a861 140 Gene3D G3DSA:1.10.260.40 3 108 1.6E-20 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 PANTHER PTHR26402:SF614 4 213 7.7E-106 T 09-11-2016 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 213 7.6E-20 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 Gene3D G3DSA:1.10.10.10 131 213 8.5E-26 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 Gene3D G3DSA:3.40.50.2300 3 121 9.9E-36 T 09-11-2016 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 Pfam PF00072 Response regulator receiver domain 6 115 2.9E-26 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 SMART SM00448 4 114 4.9E-38 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 SMART SM00862 150 213 8.4E-12 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 SUPERFAMILY SSF46894 129 211 3.4E-23 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 PANTHER PTHR26402 4 213 7.7E-106 T 09-11-2016 CLOSPO_RS06270 26ba9f3de95df8a6446f1abdbf1f6c6b 213 SUPERFAMILY SSF52172 5 120 9.68E-37 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS14595 8c9a10c6e40ccfc2b26a5204cd6ca3db 254 Pfam PF13614 AAA domain 2 179 7.5E-69 T 09-11-2016 IPR025669 AAA domain CLOSPO_RS14595 8c9a10c6e40ccfc2b26a5204cd6ca3db 254 SUPERFAMILY SSF52540 2 252 6.94E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14595 8c9a10c6e40ccfc2b26a5204cd6ca3db 254 PANTHER PTHR13696 2 254 5.5E-91 T 09-11-2016 CLOSPO_RS14595 8c9a10c6e40ccfc2b26a5204cd6ca3db 254 Gene3D G3DSA:3.40.50.300 2 253 6.1E-73 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14595 8c9a10c6e40ccfc2b26a5204cd6ca3db 254 PANTHER PTHR13696:SF52 2 254 5.5E-91 T 09-11-2016 CLOSPO_RS06465 fa864402db08fef5f4840bb7d5a0b3f3 93 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 5 43 2.0E-13 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS06465 fa864402db08fef5f4840bb7d5a0b3f3 93 Pfam PF01345 Domain of unknown function DUF11 5 36 5.6E-11 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 PANTHER PTHR30173:SF24 1 179 1.3E-41 T 09-11-2016 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 Gene3D G3DSA:1.10.10.10 119 179 2.4E-10 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 Pfam PF08281 Sigma-70, region 4 123 175 2.7E-9 T 09-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 SUPERFAMILY SSF88659 112 179 4.11E-11 T 09-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 Pfam PF04542 Sigma-70 region 2 24 91 5.3E-11 T 09-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 PANTHER PTHR30173 1 179 1.3E-41 T 09-11-2016 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 SUPERFAMILY SSF88946 4 106 3.14E-15 T 09-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 Gene3D G3DSA:1.10.1740.10 4 113 1.2E-14 T 09-11-2016 CLOSPO_RS15390 607469393cf55e6e8b8e44c119a0690c 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 179 9.3E-22 T 09-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 PANTHER PTHR22976 5 345 2.4E-119 T 09-11-2016 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 SMART SM00729 56 263 3.1E-28 T 09-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 SUPERFAMILY SSF102114 18 302 1.96E-58 T 09-11-2016 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 PIRSF PIRSF004762 1 334 1.4E-73 T 09-11-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 8 345 5.3E-170 T 09-11-2016 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 SMART SM00876 231 324 0.0033 T 09-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 PANTHER PTHR22976:SF28 5 345 2.4E-119 T 09-11-2016 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 Gene3D G3DSA:3.20.20.70 18 338 4.1E-87 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS14935 a6849b5018382fcb36a6407ed2a8b734 352 Pfam PF04055 Radical SAM superfamily 60 218 2.3E-13 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 SMART SM00387 193 300 1.9E-13 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 PANTHER PTHR24423 77 286 3.0E-50 T 09-11-2016 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 PANTHER PTHR24423 19 40 3.0E-50 T 09-11-2016 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 Pfam PF00512 His Kinase A (phospho-acceptor) domain 86 146 2.0E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 Gene3D G3DSA:1.10.287.130 75 142 3.7E-17 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 SMART SM00388 81 147 3.7E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 194 285 2.8E-14 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 SUPERFAMILY SSF55874 152 286 1.44E-26 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 PRINTS PR01780 Lantibiotic regulatory protein signature 189 204 3.1E-5 T 09-11-2016 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 PRINTS PR01780 Lantibiotic regulatory protein signature 251 266 3.1E-5 T 09-11-2016 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 PRINTS PR01780 Lantibiotic regulatory protein signature 90 106 3.1E-5 T 09-11-2016 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 SUPERFAMILY SSF47384 72 147 6.47E-17 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17305 fb881c6d35e568a8d3d352c9305b0d4a 301 Gene3D G3DSA:3.30.565.10 154 287 7.6E-27 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 09-11-2016 IPR020595 MnmG-related, conserved site CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 09-11-2016 IPR020595 MnmG-related, conserved site CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 SUPERFAMILY SSF51905 98 261 1.12E-41 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 SUPERFAMILY SSF51905 7 67 1.12E-41 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 621 1.4E-265 T 09-11-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 PANTHER PTHR11806 7 625 0.0 T 09-11-2016 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 41.945 T 09-11-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 Pfam PF01134 Glucose inhibited division protein A 9 398 1.4E-161 T 09-11-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 Pfam PF13932 GidA associated domain 401 615 7.7E-72 T 09-11-2016 IPR026904 GidA associated domain 3 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 PANTHER PTHR11806:SF0 7 625 0.0 T 09-11-2016 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 8.8E-6 T 09-11-2016 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 8.8E-6 T 09-11-2016 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 SMART SM01228 545 616 3.4E-40 T 09-11-2016 CLOSPO_RS14580 d1e95b38d5062499fd3faecc32c1aa04 625 Gene3D G3DSA:3.50.50.60 7 223 3.7E-30 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 SMART SM00388 361 433 1.0E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 588 4.0E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 4.0E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 4.0E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 4.0E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 Pfam PF00512 His Kinase A (phospho-acceptor) domain 363 433 1.1E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 SUPERFAMILY SSF55785 212 333 1.44E-6 T 09-11-2016 IPR000014 PAS domain CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 222 339 1.1E-8 T 09-11-2016 IPR000014 PAS domain CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 PANTHER PTHR24423 11 25 1.2E-86 T 09-11-2016 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 PANTHER PTHR24423 210 598 1.2E-86 T 09-11-2016 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 Gene3D G3DSA:1.10.287.130 367 418 1.0E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 SUPERFAMILY SSF55874 422 591 5.24E-45 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 Gene3D G3DSA:3.30.565.10 419 589 9.5E-46 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 588 8.7E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 SMART SM00387 479 591 2.4E-33 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 SUPERFAMILY SSF47384 350 433 9.22E-18 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12995 fc0990328636bc83f7825cffb4d2a4ab 619 Gene3D G3DSA:3.30.450.20 223 366 9.5E-10 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 PANTHER PTHR18966 36 261 2.0E-48 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 Gene3D G3DSA:3.40.190.10 118 223 1.5E-28 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 262 4.3E-69 T 09-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 SUPERFAMILY SSF53850 1 263 2.51E-75 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 Gene3D G3DSA:3.40.190.10 37 117 1.1E-46 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 Gene3D G3DSA:3.40.190.10 224 264 1.1E-46 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 PANTHER PTHR18966:SF191 36 261 2.0E-48 T 09-11-2016 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 09-11-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 SMART SM00062 40 263 3.1E-73 T 09-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOSPO_RS15565 8f05a88377fb0b64bcd88f485915681c 267 SMART SM00079 40 262 4.3E-5 T 09-11-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CLOSPO_RS07695 d826eff6455e9e4f047d9660eab7f56c 130 Gene3D G3DSA:3.40.50.300 7 117 2.0E-21 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07695 d826eff6455e9e4f047d9660eab7f56c 130 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 47 62 - T 09-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOSPO_RS07695 d826eff6455e9e4f047d9660eab7f56c 130 SUPERFAMILY SSF52540 7 127 3.84E-21 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07695 d826eff6455e9e4f047d9660eab7f56c 130 PANTHER PTHR32071 7 130 6.8E-73 T 09-11-2016 CLOSPO_RS07695 d826eff6455e9e4f047d9660eab7f56c 130 Pfam PF00158 Sigma-54 interaction domain 6 117 8.8E-36 T 09-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOSPO_RS07695 d826eff6455e9e4f047d9660eab7f56c 130 PANTHER PTHR32071:SF41 7 130 6.8E-73 T 09-11-2016 CLOSPO_RS15725 f400c73366e68df4895fe6e61b5d8d88 321 Gene3D G3DSA:3.90.1720.10 26 141 4.7E-45 T 09-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- CLOSPO_RS15725 f400c73366e68df4895fe6e61b5d8d88 321 SUPERFAMILY SSF54001 27 139 3.27E-42 T 09-11-2016 CLOSPO_RS15725 f400c73366e68df4895fe6e61b5d8d88 321 PANTHER PTHR21666 31 141 4.8E-32 T 09-11-2016 CLOSPO_RS15725 f400c73366e68df4895fe6e61b5d8d88 321 Pfam PF00877 NlpC/P60 family 43 139 2.6E-27 T 09-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 SUPERFAMILY SSF46785 1 111 2.89E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 Gene3D G3DSA:3.40.190.10 173 262 1.4E-22 T 09-11-2016 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 SUPERFAMILY SSF53850 90 292 3.55E-40 T 09-11-2016 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 Gene3D G3DSA:3.40.190.10 90 172 5.6E-17 T 09-11-2016 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.7E-8 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.7E-8 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.7E-8 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 PANTHER PTHR30126:SF11 1 293 1.8E-114 T 09-11-2016 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 Pfam PF03466 LysR substrate binding domain 89 292 3.0E-46 T 09-11-2016 IPR005119 LysR, substrate-binding CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 PANTHER PTHR30126 1 293 1.8E-114 T 09-11-2016 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.6E-18 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14885 1261be054f60e20d4b4378781814e7bf 293 Gene3D G3DSA:1.10.10.10 1 86 4.6E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 PANTHER PTHR21666:SF199 122 230 7.6E-22 T 09-11-2016 CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 34 232 9.1E-98 T 09-11-2016 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 Gene3D G3DSA:1.10.101.10 40 102 3.4E-21 T 09-11-2016 IPR002477 Peptidoglycan binding-like CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 Pfam PF07486 Cell Wall Hydrolase 133 231 1.1E-28 T 09-11-2016 IPR011105 Cell wall hydrolase, SleB GO:0016787 CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 Pfam PF01471 Putative peptidoglycan binding domain 46 101 4.4E-17 T 09-11-2016 IPR002477 Peptidoglycan binding-like CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 SUPERFAMILY SSF47090 40 102 1.1E-20 T 09-11-2016 IPR002477 Peptidoglycan binding-like CLOSPO_RS13685 408c74a9921d64e8e5ead6ff3c59def4 232 PANTHER PTHR21666 122 230 7.6E-22 T 09-11-2016 CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 1 230 2.7E-73 T 09-11-2016 IPR003797 DegV CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 PANTHER PTHR33434:SF3 1 234 1.6E-87 T 09-11-2016 CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 PANTHER PTHR33434 1 234 1.6E-87 T 09-11-2016 CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 Gene3D G3DSA:3.40.50.10170 1 131 1.0E-30 T 09-11-2016 CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 Gene3D G3DSA:3.30.1180.10 134 230 1.8E-32 T 09-11-2016 CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 SUPERFAMILY SSF82549 1 231 1.28E-63 T 09-11-2016 CLOSPO_RS04075 44680e8c127b2f3ef23a4b6264763fc2 234 Pfam PF02645 Uncharacterised protein, DegV family COG1307 1 231 1.3E-69 T 09-11-2016 IPR003797 DegV CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 PANTHER PTHR11808:SF14 1 139 2.5E-76 T 09-11-2016 CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 Gene3D G3DSA:3.40.640.10 1 115 5.4E-46 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 SUPERFAMILY SSF53383 1 139 8.92E-47 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 1 138 7.3E-59 T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 57 71 - T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 PANTHER PTHR11808 1 139 2.5E-76 T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS06845 e4b883632810471740f447e2ed026de0 139 Gene3D G3DSA:3.90.1150.10 116 139 1.1E-6 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 12 158 9.3E-46 T 09-11-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 PANTHER PTHR30352:SF2 17 171 6.5E-47 T 09-11-2016 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 Pfam PF13353 4Fe-4S single cluster domain 17 155 9.3E-38 T 09-11-2016 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 Gene3D G3DSA:3.80.30.10 68 165 2.0E-15 T 09-11-2016 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 PANTHER PTHR30352 17 171 6.5E-47 T 09-11-2016 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 09-11-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 PIRSF PIRSF000368 1 171 1.8E-54 T 09-11-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 Pfam PF04055 Radical SAM superfamily 25 112 5.1E-10 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS14260 5462b1f3eeb32e3d444db4ca4055599b 171 SUPERFAMILY SSF102114 26 106 8.89E-11 T 09-11-2016 CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 SMART SM00849 21 218 2.1E-14 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 PANTHER PTHR11935:SF95 117 232 3.1E-33 T 09-11-2016 CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 PANTHER PTHR11935:SF95 7 98 3.1E-33 T 09-11-2016 CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 PANTHER PTHR11935 117 232 3.1E-33 T 09-11-2016 CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 PANTHER PTHR11935 7 98 3.1E-33 T 09-11-2016 CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 Gene3D G3DSA:3.60.15.10 2 96 7.4E-34 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 Gene3D G3DSA:3.60.15.10 134 230 7.4E-34 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 SUPERFAMILY SSF56281 3 238 9.96E-29 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15530 27f78f63afdb589589533bd65043151e 238 Pfam PF00753 Metallo-beta-lactamase superfamily 25 184 1.1E-8 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 Pfam PF00005 ABC transporter 17 161 1.5E-28 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 PANTHER PTHR24220:SF568 3 232 3.4E-119 T 09-11-2016 CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 SMART SM00382 26 212 9.6E-5 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 Gene3D G3DSA:3.40.50.300 1 224 3.6E-57 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 SUPERFAMILY SSF52540 2 227 5.33E-55 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS15625 9ecc8f8a54bc40fae682c01b931303aa 233 PANTHER PTHR24220 3 232 3.4E-119 T 09-11-2016 CLOSPO_RS18530 204ffe20b9bda78ea2d8ff9c598c086c 232 SMART SM00873 61 215 1.9E-16 T 09-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOSPO_RS18530 204ffe20b9bda78ea2d8ff9c598c086c 232 SUPERFAMILY SSF56037 49 227 1.02E-30 T 09-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CLOSPO_RS18530 204ffe20b9bda78ea2d8ff9c598c086c 232 Gene3D G3DSA:3.50.40.10 50 194 8.2E-21 T 09-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CLOSPO_RS18530 204ffe20b9bda78ea2d8ff9c598c086c 232 Pfam PF03483 B3/4 domain 64 194 4.1E-26 T 09-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOSPO_RS18530 204ffe20b9bda78ea2d8ff9c598c086c 232 PANTHER PTHR39209:SF2 1 232 6.0E-112 T 09-11-2016 CLOSPO_RS18530 204ffe20b9bda78ea2d8ff9c598c086c 232 PANTHER PTHR39209 1 232 6.0E-112 T 09-11-2016 CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 PANTHER PTHR32114 769 1175 9.3E-120 T 09-11-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 PANTHER PTHR32114 2 722 9.3E-120 T 09-11-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 Gene3D G3DSA:3.40.50.300 900 957 2.2E-9 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 Gene3D G3DSA:3.40.50.300 1060 1171 2.2E-9 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 SUPERFAMILY SSF52540 1066 1149 4.57E-27 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 SUPERFAMILY SSF52540 4 184 4.57E-27 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 PANTHER PTHR32114:SF2 769 1175 9.3E-120 T 09-11-2016 CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 PANTHER PTHR32114:SF2 2 722 9.3E-120 T 09-11-2016 CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1060 1131 4.9E-14 T 09-11-2016 CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 Gene3D G3DSA:3.40.50.300 1 158 3.1E-24 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15695 c00a35382502a9e3c9ac89b7fab651aa 1176 Pfam PF13476 AAA domain 5 263 4.1E-23 T 09-11-2016 CLOSPO_RS16600 e11d78ae1179b3cfba028226b26c8a74 274 SUPERFAMILY SSF56281 10 104 2.83E-24 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16600 e11d78ae1179b3cfba028226b26c8a74 274 SUPERFAMILY SSF56281 138 274 2.83E-24 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16600 e11d78ae1179b3cfba028226b26c8a74 274 Pfam PF00753 Metallo-beta-lactamase superfamily 26 79 1.1E-7 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16600 e11d78ae1179b3cfba028226b26c8a74 274 PANTHER PTHR13754 1 274 3.5E-58 T 09-11-2016 CLOSPO_RS16600 e11d78ae1179b3cfba028226b26c8a74 274 Gene3D G3DSA:3.60.15.10 1 258 2.8E-24 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16600 e11d78ae1179b3cfba028226b26c8a74 274 PANTHER PTHR13754:SF13 1 274 3.5E-58 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 PANTHER PTHR32089:SF36 609 670 5.1E-247 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 Gene3D G3DSA:3.30.450.20 157 285 2.3E-23 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 SUPERFAMILY SSF103190 94 161 8.63E-6 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 SMART SM00304 307 365 0.0011 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 Gene3D G3DSA:1.10.287.950 409 627 3.5E-48 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 460 668 3.0E-39 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 PANTHER PTHR32089:SF36 97 587 5.1E-247 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 Pfam PF00672 HAMP domain 288 361 1.0E-10 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 PANTHER PTHR32089 97 587 5.1E-247 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 PANTHER PTHR32089 609 670 5.1E-247 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 SUPERFAMILY SSF58104 400 669 8.63E-68 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 SUPERFAMILY SSF58104 340 367 8.63E-68 T 09-11-2016 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 Pfam PF02743 Cache domain 36 268 1.4E-24 T 09-11-2016 IPR033479 Double Cache domain 1 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 SMART SM00283 394 669 4.3E-62 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS16900 b093e54c9d12b5643b7c624c6d92bcc6 670 Gene3D G3DSA:3.30.450.20 80 156 2.9E-18 T 09-11-2016 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 Pfam PF04397 LytTr DNA-binding domain 138 226 2.9E-22 T 09-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 PANTHER PTHR26402:SF577 2 230 5.4E-50 T 09-11-2016 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 SMART SM00850 135 227 6.5E-25 T 09-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 SUPERFAMILY SSF52172 1 127 8.11E-19 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 Gene3D G3DSA:3.40.50.2300 1 120 4.4E-21 T 09-11-2016 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 Gene3D G3DSA:2.40.50.40 126 195 2.8E-21 T 09-11-2016 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 Pfam PF00072 Response regulator receiver domain 5 114 3.9E-16 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 PANTHER PTHR26402 2 230 5.4E-50 T 09-11-2016 CLOSPO_RS18745 0eed5b9c3dab0ba6a8f57890e7d1cdfa 235 SMART SM00448 2 115 4.9E-14 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SUPERFAMILY SSF48452 346 429 2.28E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 Pfam PF13181 Tetratricopeptide repeat 197 219 0.014 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SUPERFAMILY SSF48452 71 219 3.08E-13 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 Gene3D G3DSA:1.25.40.10 75 219 8.4E-12 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 PANTHER PTHR10098:SF104 1 428 1.3E-100 T 09-11-2016 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SUPERFAMILY SSF47413 4 68 1.1E-13 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 PANTHER PTHR10098 1 428 1.3E-100 T 09-11-2016 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 75 108 120.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 155 188 170.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 355 388 190.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 237 270 18.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 395 428 90.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 197 230 15.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00028 277 310 10.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SMART SM00530 9 63 9.0E-11 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 Pfam PF12844 Helix-turn-helix domain 7 67 2.8E-11 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 Pfam PF13424 Tetratricopeptide repeat 237 309 2.7E-9 T 09-11-2016 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 Gene3D G3DSA:1.10.260.40 6 74 4.5E-17 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 SUPERFAMILY SSF48452 177 351 1.06E-20 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12630 141d996d33078c060b308c1229ff164c 434 Gene3D G3DSA:1.25.40.10 226 425 8.9E-19 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 SMART SM00382 191 330 1.5E-26 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 106 598 6.3E-237 T 09-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 PANTHER PTHR23076 10 598 2.2E-301 T 09-11-2016 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 195 326 1.4E-45 T 09-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 SUPERFAMILY SSF52540 151 398 1.15E-75 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 ProSitePatterns PS00674 AAA-protein family signature. 298 316 - T 09-11-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 Pfam PF01434 Peptidase family M41 389 597 1.4E-78 T 09-11-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 601 37.69 T 09-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 Gene3D G3DSA:3.40.50.300 152 336 3.2E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 Gene3D G3DSA:1.10.8.60 337 402 2.0E-25 T 09-11-2016 CLOSPO_RS15275 f8d219b4149f4f23fdb70cb2c1faa159 601 SUPERFAMILY SSF140990 409 600 1.57E-71 T 09-11-2016 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 Pfam PF00204 DNA gyrase B 40 213 6.4E-54 T 09-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 ProSitePatterns PS00177 DNA topoisomerase II signature. 245 253 - T 09-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 Pfam PF01751 Toprim domain 243 351 7.8E-17 T 09-11-2016 IPR006171 Toprim domain CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 387 424 5.7E-18 T 09-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PANTHER PTHR10169 1 424 2.3E-147 T 09-11-2016 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 Gene3D G3DSA:3.40.50.670 228 424 2.2E-71 T 09-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 135 151 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 412 424 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 183 197 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 293 302 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 13 26 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 39 61 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR01159 DNA gyrase subunit B signature 197 217 1.7E-31 T 09-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 SMART SM00433 1 424 1.7E-78 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 SUPERFAMILY SSF56719 223 424 3.92E-67 T 09-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 Gene3D G3DSA:3.30.565.10 2 46 1.4E-4 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR00418 DNA topoisomerase II family signature 309 325 4.8E-43 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR00418 DNA topoisomerase II family signature 391 407 4.8E-43 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR00418 DNA topoisomerase II family signature 91 104 4.8E-43 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR00418 DNA topoisomerase II family signature 243 257 4.8E-43 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR00418 DNA topoisomerase II family signature 347 359 4.8E-43 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PRINTS PR00418 DNA topoisomerase II family signature 327 344 4.8E-43 T 09-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 PANTHER PTHR10169:SF44 1 424 2.3E-147 T 09-11-2016 CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 Gene3D G3DSA:3.30.230.10 47 213 1.8E-54 T 09-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOSPO_RS10895 b2cfc664ade0220a7a5076a9201e1fb1 424 SUPERFAMILY SSF54211 40 213 3.22E-47 T 09-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold CLOSPO_RS08670 e1cf41bc09efa63ddeaa3af2ed0ab674 509 PANTHER PTHR32329 1 509 0.0 T 09-11-2016 CLOSPO_RS08670 e1cf41bc09efa63ddeaa3af2ed0ab674 509 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 345 506 2.2E-35 T 09-11-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit CLOSPO_RS08670 e1cf41bc09efa63ddeaa3af2ed0ab674 509 PANTHER PTHR32329:SF4 1 509 0.0 T 09-11-2016 CLOSPO_RS08670 e1cf41bc09efa63ddeaa3af2ed0ab674 509 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 111 330 1.3E-83 T 09-11-2016 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 Gene3D G3DSA:3.40.50.1970 1 157 1.0E-34 T 09-11-2016 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 PANTHER PTHR11496:SF57 1 371 5.0E-188 T 09-11-2016 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 SUPERFAMILY SSF56796 3 366 1.83E-77 T 09-11-2016 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 Gene3D G3DSA:1.20.1090.10 158 374 1.2E-67 T 09-11-2016 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 148 176 - T 09-11-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 358 1.6E-59 T 09-11-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 PANTHER PTHR11496 1 371 5.0E-188 T 09-11-2016 CLOSPO_RS18290 1c0530ebd3f551806bd75fd6de8d7e43 376 PIRSF PIRSF000112 1 370 1.5E-83 T 09-11-2016 CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 PANTHER PTHR30595:SF3 2 302 4.4E-85 T 09-11-2016 CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 Pfam PF08279 HTH domain 5 55 2.2E-10 T 09-11-2016 IPR013196 Helix-turn-helix, type 11 CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 PIRSF PIRSF016838 1 310 1.9E-19 T 09-11-2016 IPR028349 Protein PafC CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 Gene3D G3DSA:1.10.10.10 4 58 7.3E-11 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 Pfam PF13280 WYL domain 137 305 2.5E-33 T 09-11-2016 IPR026881 WYL domain CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 PANTHER PTHR30595 2 302 4.4E-85 T 09-11-2016 CLOSPO_RS17710 df361fa6f1cb7afc5fcd835bbeb33ad8 310 SUPERFAMILY SSF46785 4 58 3.23E-8 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Gene3D G3DSA:3.40.120.10 19 217 5.9E-63 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Gene3D G3DSA:3.40.120.10 307 451 9.8E-33 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 180 6.4E-44 T 09-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 507 553 1.2E-9 T 09-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 2.9E-7 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 294 309 2.9E-7 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 246 2.9E-7 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Gene3D G3DSA:3.40.120.10 228 306 1.6E-21 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 SUPERFAMILY SSF53738 302 452 4.32E-29 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PANTHER PTHR22573 496 573 2.4E-243 T 09-11-2016 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PANTHER PTHR22573 19 480 2.4E-243 T 09-11-2016 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 322 447 5.6E-20 T 09-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 313 2.1E-22 T 09-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 SUPERFAMILY SSF55957 441 478 2.88E-15 T 09-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 SUPERFAMILY SSF55957 510 570 2.88E-15 T 09-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PANTHER PTHR22573:SF54 496 573 2.4E-243 T 09-11-2016 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 PANTHER PTHR22573:SF54 19 480 2.4E-243 T 09-11-2016 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 Gene3D G3DSA:3.30.310.50 477 568 8.0E-25 T 09-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 SUPERFAMILY SSF53738 29 234 2.94E-48 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 SUPERFAMILY SSF53738 210 316 1.37E-19 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS14700 514a02df2c62d1798b2029c244f98506 573 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 09-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 PIRSF PIRSF000440 1 208 1.3E-62 T 09-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 SMART SM01059 1 201 2.3E-96 T 09-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 SUPERFAMILY SSF52777 2 206 1.33E-54 T 09-11-2016 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 Gene3D G3DSA:3.30.559.10 1 205 3.9E-69 T 09-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 PANTHER PTHR38474 1 207 1.7E-109 T 09-11-2016 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 11 200 7.0E-75 T 09-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 Pfam PF00302 Chloramphenicol acetyltransferase 2 201 5.3E-43 T 09-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CLOSPO_RS16475 a7e6d7ee9bed70b362191bc2b60fecc7 208 PANTHER PTHR38474:SF1 1 207 1.7E-109 T 09-11-2016 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 PANTHER PTHR23135 5 448 9.6E-195 T 09-11-2016 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Gene3D G3DSA:3.90.190.20 317 456 1.2E-50 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 398 2.0E-22 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Gene3D G3DSA:3.40.1190.10 99 316 1.8E-70 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 PANTHER PTHR23135:SF5 5 448 9.6E-195 T 09-11-2016 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 12 453 8.4E-147 T 09-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Pfam PF01225 Mur ligase family, catalytic domain 12 110 5.8E-26 T 09-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 SUPERFAMILY SSF53244 314 456 6.54E-45 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 SUPERFAMILY SSF53623 96 312 1.7E-61 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 SUPERFAMILY SSF51984 10 97 1.19E-27 T 09-11-2016 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Gene3D G3DSA:3.40.50.720 11 97 3.8E-35 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 10 458 39.205 T 09-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15125 fc5a2ab33720927bc9818dae23c2c7c5 458 Pfam PF08245 Mur ligase middle domain 116 294 1.1E-33 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 5 368 1.1E-67 T 09-11-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 Gene3D G3DSA:3.90.100.10 404 481 5.8E-19 T 09-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 SUPERFAMILY SSF53383 5 391 1.33E-74 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 Gene3D G3DSA:3.40.640.10 5 282 2.2E-89 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 Gene3D G3DSA:3.90.1150.10 293 403 1.1E-13 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 PANTHER PTHR11751:SF360 5 388 6.8E-182 T 09-11-2016 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 413 457 4.5E-7 T 09-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CLOSPO_RS14460 c6fce3343fe4fb1fe090ddb262bbb92c 481 PANTHER PTHR11751 5 388 6.8E-182 T 09-11-2016 CLOSPO_RS18700 e7ad4ed3a358d7cd4b51b2494e5f6421 251 Gene3D G3DSA:3.40.50.300 1 230 3.4E-64 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18700 e7ad4ed3a358d7cd4b51b2494e5f6421 251 SUPERFAMILY SSF52540 1 227 2.72E-60 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18700 e7ad4ed3a358d7cd4b51b2494e5f6421 251 SMART SM00382 26 213 3.0E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18700 e7ad4ed3a358d7cd4b51b2494e5f6421 251 Pfam PF00005 ABC transporter 18 164 5.0E-32 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18700 e7ad4ed3a358d7cd4b51b2494e5f6421 251 PANTHER PTHR24220:SF471 3 250 5.1E-157 T 09-11-2016 CLOSPO_RS18700 e7ad4ed3a358d7cd4b51b2494e5f6421 251 PANTHER PTHR24220 3 250 5.1E-157 T 09-11-2016 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 PIRSF PIRSF002808 6 441 6.3E-162 T 09-11-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 Gene3D G3DSA:1.20.1250.20 235 438 1.8E-42 T 09-11-2016 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 Gene3D G3DSA:1.20.1250.20 23 219 3.3E-51 T 09-11-2016 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 4 433 1.3E-198 T 09-11-2016 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 412 2.5E-146 T 09-11-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 PANTHER PTHR11662:SF141 2 439 1.5E-230 T 09-11-2016 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 ProSitePatterns PS00942 glpT family of transporters signature. 150 166 - T 09-11-2016 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 Pfam PF07690 Major Facilitator Superfamily 36 391 2.5E-51 T 09-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 SUPERFAMILY SSF103473 10 431 1.22E-82 T 09-11-2016 IPR020846 Major facilitator superfamily domain CLOSPO_RS18875 7bf2be69634414f342f3e651d1abe815 441 PANTHER PTHR11662 2 439 1.5E-230 T 09-11-2016 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 Gene3D G3DSA:3.40.50.2300 1 75 1.6E-19 T 09-11-2016 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 SUPERFAMILY SSF46894 79 154 2.18E-20 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 SUPERFAMILY SSF52172 1 66 1.71E-22 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 SMART SM00862 98 154 1.1E-8 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 Pfam PF00072 Response regulator receiver domain 1 60 4.5E-13 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 Pfam PF00486 Transcriptional regulatory protein, C terminal 99 154 5.1E-18 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 PANTHER PTHR26402 1 154 3.8E-50 T 09-11-2016 CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 Gene3D G3DSA:1.10.10.10 79 154 1.7E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS04155 fcf87ce9cff750dec7394cd293c3a95d 154 PANTHER PTHR26402:SF292 1 154 3.8E-50 T 09-11-2016 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 Gene3D G3DSA:3.40.50.10490 63 252 2.8E-26 T 09-11-2016 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 PANTHER PTHR30514 2 251 1.8E-78 T 09-11-2016 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 SUPERFAMILY SSF53697 95 252 6.97E-27 T 09-11-2016 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 Gene3D G3DSA:1.10.10.10 9 62 3.1E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 SUPERFAMILY SSF46689 7 73 1.97E-18 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 PANTHER PTHR30514:SF1 2 251 1.8E-78 T 09-11-2016 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 Pfam PF01380 SIS domain 118 217 1.9E-14 T 09-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 CLOSPO_RS13285 f42fe1fd96f51aa6f6e6ba4ace696d69 255 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 73 3.1E-19 T 09-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 Gene3D G3DSA:3.40.50.2300 7 129 9.1E-43 T 09-11-2016 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 5.2E-28 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 PANTHER PTHR26402:SF609 6 227 2.7E-133 T 09-11-2016 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 SUPERFAMILY SSF52172 7 181 6.45E-45 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 SMART SM00862 151 225 4.8E-29 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 Gene3D G3DSA:1.10.10.10 130 227 6.0E-37 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 SMART SM00448 6 116 2.3E-45 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 PANTHER PTHR26402 6 227 2.7E-133 T 09-11-2016 CLOSPO_RS15150 2c0de7115ae232394c240ebda06f05f0 228 Pfam PF00072 Response regulator receiver domain 8 117 6.0E-31 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 PANTHER PTHR19211:SF54 1 208 1.0E-127 T 09-11-2016 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 SUPERFAMILY SSF52540 4 179 1.07E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16105 021872b0abd589698425578854d47962 552 SMART SM00382 28 171 2.7E-9 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16105 021872b0abd589698425578854d47962 552 SMART SM00382 313 475 2.2E-10 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16105 021872b0abd589698425578854d47962 552 PANTHER PTHR19211 1 208 1.0E-127 T 09-11-2016 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 PANTHER PTHR19211 231 527 1.0E-127 T 09-11-2016 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 SUPERFAMILY SSF52540 280 493 8.08E-42 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Pfam PF12848 ABC transporter 165 224 9.6E-5 T 09-11-2016 IPR032781 ABC-transporter extension domain CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Gene3D G3DSA:3.40.50.300 190 269 4.1E-6 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16105 021872b0abd589698425578854d47962 552 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Gene3D G3DSA:3.40.50.300 286 508 3.6E-45 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Gene3D G3DSA:3.40.50.300 3 74 1.9E-18 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16105 021872b0abd589698425578854d47962 552 PANTHER PTHR19211:SF54 231 527 1.0E-127 T 09-11-2016 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Pfam PF00005 ABC transporter 95 126 3.7E-5 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Pfam PF00005 ABC transporter 305 430 6.0E-20 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Pfam PF00005 ABC transporter 23 64 5.7E-11 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16105 021872b0abd589698425578854d47962 552 Gene3D G3DSA:3.40.50.300 78 173 1.7E-22 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS09045 36a1d8c3162a75120f76d4bd6103a554 233 Gene3D G3DSA:3.40.640.10 1 95 3.1E-33 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS09045 36a1d8c3162a75120f76d4bd6103a554 233 PANTHER PTHR11751 1 194 2.4E-52 T 09-11-2016 CLOSPO_RS09045 36a1d8c3162a75120f76d4bd6103a554 233 Gene3D G3DSA:3.90.1150.10 127 207 3.9E-12 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS09045 36a1d8c3162a75120f76d4bd6103a554 233 PANTHER PTHR11751:SF435 1 194 2.4E-52 T 09-11-2016 CLOSPO_RS09045 36a1d8c3162a75120f76d4bd6103a554 233 SUPERFAMILY SSF53383 1 196 2.12E-41 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS09045 36a1d8c3162a75120f76d4bd6103a554 233 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 2 182 2.5E-27 T 09-11-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 SUPERFAMILY SSF52440 1 94 2.97E-29 T 09-11-2016 IPR016185 Pre-ATP-grasp domain CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 PIRSF PIRSF039102 42 300 1.1E-91 T 09-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 294 1.3E-91 T 09-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 PANTHER PTHR23132 1 297 1.7E-85 T 09-11-2016 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 296 35.203 T 09-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 PANTHER PTHR23132:SF0 1 297 1.7E-85 T 09-11-2016 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 61 72 - T 09-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 239 266 - T 09-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 SMART SM01209 93 263 0.0046 T 09-11-2016 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Pfam PF07478 D-ala D-ala ligase C-terminus 102 292 3.1E-49 T 09-11-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 SUPERFAMILY SSF56059 94 292 1.46E-48 T 09-11-2016 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Gene3D G3DSA:3.30.1490.20 94 171 6.5E-23 T 09-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Pfam PF01820 D-ala D-ala ligase N-terminus 2 84 1.7E-24 T 09-11-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Gene3D G3DSA:3.40.50.20 1 81 1.6E-27 T 09-11-2016 IPR016185 Pre-ATP-grasp domain CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Gene3D G3DSA:3.30.470.20 172 294 1.9E-43 T 09-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CLOSPO_RS15600 9e300f183032bed2a03ba9f8cc1047c4 300 Gene3D G3DSA:3.30.470.20 83 93 1.9E-43 T 09-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CLOSPO_RS18345 9d4c611add39a788f500c238dcbe7455 105 SUPERFAMILY SSF46785 6 100 2.84E-17 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18345 9d4c611add39a788f500c238dcbe7455 105 PANTHER PTHR33169 1 102 2.5E-44 T 09-11-2016 CLOSPO_RS18345 9d4c611add39a788f500c238dcbe7455 105 PANTHER PTHR33169:SF13 1 102 2.5E-44 T 09-11-2016 CLOSPO_RS18345 9d4c611add39a788f500c238dcbe7455 105 Pfam PF03551 Transcriptional regulator PadR-like family 18 82 2.6E-11 T 09-11-2016 IPR005149 Transcription regulator PadR, N-terminal CLOSPO_RS18345 9d4c611add39a788f500c238dcbe7455 105 Gene3D G3DSA:1.10.10.10 11 98 4.1E-17 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 SUPERFAMILY SSF46785 2 59 5.55E-10 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 PANTHER PTHR30595 1 309 5.0E-32 T 09-11-2016 CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 Gene3D G3DSA:1.10.10.10 2 62 3.9E-13 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 SMART SM00420 5 61 0.0051 T 09-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 Pfam PF13280 WYL domain 133 300 1.2E-24 T 09-11-2016 IPR026881 WYL domain CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 PIRSF PIRSF016838 1 308 4.9E-18 T 09-11-2016 IPR028349 Protein PafC CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 PANTHER PTHR30595:SF5 1 309 5.0E-32 T 09-11-2016 CLOSPO_RS17045 150b64e81f78b9b8cbf055fdc7d67b06 309 Pfam PF08279 HTH domain 7 59 6.0E-14 T 09-11-2016 IPR013196 Helix-turn-helix, type 11 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 463 3.2E-14 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 SUPERFAMILY SSF55874 329 469 3.93E-28 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 Pfam PF00672 HAMP domain 176 239 3.1E-9 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 PANTHER PTHR24423 185 461 1.1E-52 T 09-11-2016 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 PANTHER PTHR24423 90 104 1.1E-52 T 09-11-2016 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 Gene3D G3DSA:3.30.565.10 329 462 4.5E-27 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 321 7.0E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 SMART SM00388 258 325 4.3E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 SUPERFAMILY SSF158472 193 242 1.7E-8 T 09-11-2016 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 SUPERFAMILY SSF47384 245 321 1.82E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 SMART SM00304 191 243 2.1E-7 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 SMART SM00387 368 473 1.5E-20 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16405 14ec428556cf1d84f8a3086f48608e8b 473 Gene3D G3DSA:1.10.287.130 252 321 2.3E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 SMART SM00729 113 308 0.0046 T 09-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 PANTHER PTHR11228 63 431 3.4E-157 T 09-11-2016 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 SUPERFAMILY SSF102114 111 394 3.66E-52 T 09-11-2016 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 Pfam PF04055 Radical SAM superfamily 118 247 2.6E-15 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 Gene3D G3DSA:3.20.20.70 111 392 9.4E-45 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 Pfam PF13353 4Fe-4S single cluster domain 122 205 1.4E-6 T 09-11-2016 CLOSPO_RS14195 5f8f5a3f5e794526d63cecd3f4fbf258 460 PANTHER PTHR11228:SF19 63 431 3.4E-157 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 580 693 1.1E-36 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 351 8.6E-29 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 176 1.8E-19 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PANTHER PTHR24093 761 872 0.0 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PANTHER PTHR24093 2 745 0.0 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF81660 333 515 1.94E-52 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Pfam PF00122 E1-E2 ATPase 81 315 2.7E-67 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Gene3D G3DSA:3.40.1110.10 315 514 5.8E-62 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Gene3D G3DSA:2.70.150.10 12 54 1.5E-44 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Gene3D G3DSA:2.70.150.10 108 224 1.5E-44 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 70 4.4E-22 T 09-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF56784 322 342 2.14E-61 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF56784 464 713 2.14E-61 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Pfam PF00702 haloacid dehalogenase-like hydrolase 320 623 2.9E-21 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF81665 2 113 9.42E-139 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF81665 225 318 9.42E-139 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF81665 659 869 9.42E-139 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Pfam PF00689 Cation transporting ATPase, C-terminus 693 866 3.8E-50 T 09-11-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 1.1E-42 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 1.1E-42 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 1.1E-42 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 628 1.1E-42 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 645 1.1E-42 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 1.1E-42 T 09-11-2016 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 7 864 8.4E-161 T 09-11-2016 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 666 5.7E-20 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 5.7E-20 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 467 485 5.7E-20 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 625 5.7E-20 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 09-11-2016 IPR018303 P-type ATPase, phosphorylation site CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Gene3D G3DSA:1.20.1110.10 55 107 1.6E-126 T 09-11-2016 IPR023298 P-type ATPase, transmembrane domain CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 Gene3D G3DSA:1.20.1110.10 578 868 1.6E-126 T 09-11-2016 IPR023298 P-type ATPase, transmembrane domain CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SMART SM00831 1 75 1.8E-28 T 09-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 TIGRFAM TIGR01522 ATPase-IIA2_Ca: calcium-transporting P-type ATPase, PMR1-type 7 870 5.4E-242 T 09-11-2016 IPR006413 P-type ATPase, subfamily IIA, PMR1-type GO:0005388|GO:0006816|GO:0016021 CLOSPO_RS16005 8f2aaf2d06dd2ae9a3361d0b489c5386 872 SUPERFAMILY SSF81653 113 224 2.09E-30 T 09-11-2016 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 Pfam PF13458 Periplasmic binding protein 36 357 1.4E-75 T 09-11-2016 IPR028081 Leucine-binding protein domain CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 SUPERFAMILY SSF53822 35 377 4.71E-94 T 09-11-2016 IPR028082 Periplasmic binding protein-like I CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 PANTHER PTHR30483:SF6 5 378 4.1E-121 T 09-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 Gene3D G3DSA:3.40.50.2300 160 310 3.1E-44 T 09-11-2016 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 37 53 1.2E-12 T 09-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 59 75 1.2E-12 T 09-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 265 283 1.2E-12 T 09-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 78 96 1.2E-12 T 09-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 PANTHER PTHR30483 5 378 4.1E-121 T 09-11-2016 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 Gene3D G3DSA:3.40.50.2300 311 360 5.7E-56 T 09-11-2016 CLOSPO_RS15605 60ab382bd8cc4c97631a1a2d05a68cf0 380 Gene3D G3DSA:3.40.50.2300 34 159 5.7E-56 T 09-11-2016 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 SUPERFAMILY SSF46785 4 83 2.06E-13 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 SMART SM00345 12 71 3.4E-10 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 Pfam PF02080 TrkA-C domain 133 203 1.4E-16 T 09-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 Gene3D G3DSA:3.30.70.1450 131 204 1.8E-21 T 09-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 PANTHER PTHR30445 1 203 1.6E-45 T 09-11-2016 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 Gene3D G3DSA:1.10.10.10 2 75 1.7E-16 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 PANTHER PTHR30445:SF3 1 203 1.6E-45 T 09-11-2016 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 SUPERFAMILY SSF116726 123 203 4.05E-18 T 09-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CLOSPO_RS15920 22a6f15a0885b5293357ae26269dc756 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 2.8E-9 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS16185 b369bbc07030718de9a2fb2762ccce3d 284 PANTHER PTHR14136:SF0 7 265 3.5E-50 T 09-11-2016 CLOSPO_RS16185 b369bbc07030718de9a2fb2762ccce3d 284 SUPERFAMILY SSF141571 173 279 8.5E-20 T 09-11-2016 CLOSPO_RS16185 b369bbc07030718de9a2fb2762ccce3d 284 SUPERFAMILY SSF141571 61 94 8.5E-20 T 09-11-2016 CLOSPO_RS16185 b369bbc07030718de9a2fb2762ccce3d 284 PANTHER PTHR14136 7 265 3.5E-50 T 09-11-2016 CLOSPO_RS16185 b369bbc07030718de9a2fb2762ccce3d 284 Pfam PF00805 Pentapeptide repeats (8 copies) 214 252 1.9E-10 T 09-11-2016 IPR001646 Pentapeptide repeat CLOSPO_RS14565 3949450eb2af51b7f83235d0428162c6 217 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 29 208 2.3E-64 T 09-11-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CLOSPO_RS14565 3949450eb2af51b7f83235d0428162c6 217 Pfam PF02096 60Kd inner membrane protein 30 208 5.0E-62 T 09-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CLOSPO_RS14565 3949450eb2af51b7f83235d0428162c6 217 PANTHER PTHR12428:SF14 7 212 3.1E-63 T 09-11-2016 CLOSPO_RS14565 3949450eb2af51b7f83235d0428162c6 217 PANTHER PTHR12428 7 212 3.1E-63 T 09-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CLOSPO_RS14565 3949450eb2af51b7f83235d0428162c6 217 PRINTS PR00701 60kDa inner membrane protein signature 174 197 2.6E-14 T 09-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CLOSPO_RS14565 3949450eb2af51b7f83235d0428162c6 217 PRINTS PR00701 60kDa inner membrane protein signature 91 114 2.6E-14 T 09-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 7.3E-21 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 SUPERFAMILY SSF46894 129 227 1.22E-22 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 SUPERFAMILY SSF52172 2 124 1.24E-34 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 PANTHER PTHR26402:SF519 3 230 2.9E-137 T 09-11-2016 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 Gene3D G3DSA:1.10.10.10 129 227 1.1E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 SMART SM00862 151 226 3.7E-20 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 Gene3D G3DSA:3.40.50.2300 2 120 8.7E-34 T 09-11-2016 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 SMART SM00448 3 113 1.6E-31 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 Pfam PF00072 Response regulator receiver domain 5 113 1.1E-23 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13090 9d8df33cb98543ea5be9bda4288e689f 230 PANTHER PTHR26402 3 230 2.9E-137 T 09-11-2016 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 2 457 1.5E-194 T 09-11-2016 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 PANTHER PTHR22976 1 403 3.1E-246 T 09-11-2016 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 Gene3D G3DSA:3.20.20.70 34 328 3.2E-42 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 Pfam PF04055 Radical SAM superfamily 80 228 6.2E-9 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 SUPERFAMILY SSF102114 35 337 1.96E-45 T 09-11-2016 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 262 366 9.6E-22 T 09-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 PANTHER PTHR22976:SF2 1 403 3.1E-246 T 09-11-2016 CLOSPO_RS14930 13d7e24be1e0903868303c229f555415 458 SMART SM00876 262 369 5.5E-32 T 09-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 SUPERFAMILY SSF46604 88 132 1.44E-7 T 09-11-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 SUPERFAMILY SSF51344 4 84 3.27E-18 T 09-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 PANTHER PTHR13822 1 129 1.7E-31 T 09-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 130 16.856 T 09-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 5.0E-14 T 09-11-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 130 1.2E-24 T 09-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 83 1.4E-17 T 09-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 Gene3D G3DSA:2.60.15.10 4 91 1.7E-21 T 09-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 19 90 7.0E-8 T 09-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13940 69509ec3f4151996e005813003a5c753 133 Gene3D G3DSA:1.20.5.440 92 132 5.3E-14 T 09-11-2016 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 Gene3D G3DSA:1.10.10.60 240 292 5.3E-15 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 PANTHER PTHR11019:SF11 209 347 8.5E-28 T 09-11-2016 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 Gene3D G3DSA:1.10.10.60 293 338 2.6E-11 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 SUPERFAMILY SSF46689 241 289 1.79E-8 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 Pfam PF10114 Sensory domain found in PocR 11 176 1.7E-50 T 09-11-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 SUPERFAMILY SSF46689 293 340 7.17E-10 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 293 335 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 PANTHER PTHR11019 209 347 8.5E-28 T 09-11-2016 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 Pfam PF12833 Helix-turn-helix domain 263 335 6.2E-17 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18295 cb9cc59de8496b2dc45d21e975ff4549 348 SMART SM00342 256 339 4.7E-24 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17630 c85c9ae0b24a39a22a74d276fa5599f8 64 SMART SM00530 4 59 7.3E-19 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17630 c85c9ae0b24a39a22a74d276fa5599f8 64 PANTHER PTHR10245 1 64 4.4E-21 T 09-11-2016 CLOSPO_RS17630 c85c9ae0b24a39a22a74d276fa5599f8 64 PANTHER PTHR10245:SF26 1 64 4.4E-21 T 09-11-2016 CLOSPO_RS17630 c85c9ae0b24a39a22a74d276fa5599f8 64 SUPERFAMILY SSF47413 2 63 1.66E-19 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17630 c85c9ae0b24a39a22a74d276fa5599f8 64 Gene3D G3DSA:1.10.260.40 1 63 9.7E-26 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17630 c85c9ae0b24a39a22a74d276fa5599f8 64 Pfam PF01381 Helix-turn-helix 5 59 2.2E-17 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 PIRSF PIRSF006092 1 160 6.7E-52 T 09-11-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 3.1E-58 T 09-11-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 PANTHER PTHR30437 1 157 3.3E-67 T 09-11-2016 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.448 T 09-11-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 SUPERFAMILY SSF54534 84 157 2.65E-22 T 09-11-2016 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 SUPERFAMILY SSF46557 5 80 5.1E-27 T 09-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 Gene3D G3DSA:3.10.50.30 79 158 1.1E-29 T 09-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 Gene3D G3DSA:1.10.287.180 5 78 4.4E-31 T 09-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 09-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 158 3.1E-26 T 09-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 4.2E-30 T 09-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOSPO_RS15300 094b3edfd3a9c5c5fff15c84d3b7cc85 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 09-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CLOSPO_RS15570 ff1d1d35d67f3b23a8aeb33e711c451f 242 Pfam PF13649 Methyltransferase domain 89 196 6.7E-19 T 09-11-2016 CLOSPO_RS15570 ff1d1d35d67f3b23a8aeb33e711c451f 242 SUPERFAMILY SSF53335 69 217 9.12E-28 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS15570 ff1d1d35d67f3b23a8aeb33e711c451f 242 Gene3D G3DSA:3.40.50.150 71 216 2.1E-28 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS15570 ff1d1d35d67f3b23a8aeb33e711c451f 242 PANTHER PTHR10108 67 210 1.3E-18 T 09-11-2016 CLOSPO_RS15570 ff1d1d35d67f3b23a8aeb33e711c451f 242 PANTHER PTHR10108 8 34 1.3E-18 T 09-11-2016 CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 Gene3D G3DSA:3.30.565.10 178 323 3.4E-29 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 3.3E-10 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 3.3E-10 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 3.3E-10 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 325 3.3E-10 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 SMART SM00387 216 326 2.7E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 SUPERFAMILY SSF55874 163 325 3.01E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 PANTHER PTHR24423 117 324 1.7E-69 T 09-11-2016 CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 221 325 4.7E-17 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13085 a4f46a0f6ba0b913b43b05e5025141c8 326 PANTHER PTHR24423:SF539 117 324 1.7E-69 T 09-11-2016 CLOSPO_RS14650 670dc4ae79762cb9032eeacfa7a9f089 382 PANTHER PTHR30548:SF6 1 382 5.5E-266 T 09-11-2016 CLOSPO_RS14650 670dc4ae79762cb9032eeacfa7a9f089 382 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 37 382 3.9E-84 T 09-11-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit CLOSPO_RS14650 670dc4ae79762cb9032eeacfa7a9f089 382 PANTHER PTHR30548 1 382 5.5E-266 T 09-11-2016 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 SUPERFAMILY SSF58104 387 662 5.14E-59 T 09-11-2016 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 PANTHER PTHR32089:SF1 1 663 5.4E-193 T 09-11-2016 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 457 637 1.6E-39 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 SUPERFAMILY SSF103190 67 189 1.46E-12 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 Pfam PF02743 Cache domain 41 265 6.8E-38 T 09-11-2016 IPR033479 Double Cache domain 1 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 SMART SM00283 387 662 3.6E-52 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 514 543 2.0E-5 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 2.0E-5 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 PANTHER PTHR32089 1 663 5.4E-193 T 09-11-2016 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 Gene3D G3DSA:1.10.287.950 402 619 9.8E-47 T 09-11-2016 CLOSPO_RS16100 2a50cf81f65f8b0d70dc927e3c6812a1 663 Gene3D G3DSA:3.30.450.20 147 279 4.4E-28 T 09-11-2016 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 5.3E-19 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 367 5.3E-19 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 5.3E-19 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 5.3E-19 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PANTHER PTHR24423 35 77 2.5E-113 T 09-11-2016 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 SMART SM00387 302 414 1.6E-38 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 Pfam PF00672 HAMP domain 120 188 7.9E-10 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 Gene3D G3DSA:1.10.287.130 184 254 4.2E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PANTHER PTHR24423 134 417 2.5E-113 T 09-11-2016 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 Gene3D G3DSA:3.30.565.10 259 413 6.4E-49 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 195 256 3.9E-12 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 SUPERFAMILY SSF55874 249 412 6.81E-46 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PANTHER PTHR24423:SF546 35 77 2.5E-113 T 09-11-2016 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 SUPERFAMILY SSF47384 177 259 5.49E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 411 3.1E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 SUPERFAMILY SSF158472 141 189 4.58E-6 T 09-11-2016 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 SMART SM00388 194 258 4.8E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 SMART SM00304 140 193 0.0054 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13320 5192b3af11c765929bfd3898f3112f6a 417 PANTHER PTHR24423:SF546 134 417 2.5E-113 T 09-11-2016 CLOSPO_RS13905 b4ecaf9e86a3a269dcdbd570c9dcafb3 174 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 28 165 1.0E-46 T 09-11-2016 IPR009665 Protein of unknown function DUF1256 CLOSPO_RS13905 b4ecaf9e86a3a269dcdbd570c9dcafb3 174 Pfam PF06866 Protein of unknown function (DUF1256) 6 163 1.3E-63 T 09-11-2016 IPR009665 Protein of unknown function DUF1256 CLOSPO_RS13905 b4ecaf9e86a3a269dcdbd570c9dcafb3 174 SUPERFAMILY SSF53163 10 171 4.18E-45 T 09-11-2016 IPR023430 Peptidase HybD-like domain CLOSPO_RS06565 f41537bf50d61de3d04fb0d03e28b124 147 SUPERFAMILY SSF103473 2 144 1.83E-26 T 09-11-2016 IPR020846 Major facilitator superfamily domain CLOSPO_RS06565 f41537bf50d61de3d04fb0d03e28b124 147 Pfam PF07690 Major Facilitator Superfamily 3 142 2.2E-14 T 09-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOSPO_RS06565 f41537bf50d61de3d04fb0d03e28b124 147 Gene3D G3DSA:1.20.1250.20 2 143 1.4E-32 T 09-11-2016 CLOSPO_RS06565 f41537bf50d61de3d04fb0d03e28b124 147 PANTHER PTHR11662:SF141 1 146 3.2E-69 T 09-11-2016 CLOSPO_RS06565 f41537bf50d61de3d04fb0d03e28b124 147 PANTHER PTHR11662 1 146 3.2E-69 T 09-11-2016 CLOSPO_RS18600 df2eee2dc5baeefa8682eb65974c019b 145 SUPERFAMILY SSF55729 1 141 4.36E-21 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18600 df2eee2dc5baeefa8682eb65974c019b 145 Gene3D G3DSA:3.40.630.30 1 136 2.6E-21 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18600 df2eee2dc5baeefa8682eb65974c019b 145 Pfam PF13673 Acetyltransferase (GNAT) domain 37 137 2.6E-10 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 PANTHER PTHR11019:SF56 2 112 1.1E-45 T 09-11-2016 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 SUPERFAMILY SSF46689 5 55 2.64E-8 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 SMART SM00871 128 283 1.8E-29 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 SUPERFAMILY SSF46689 57 110 5.82E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 Pfam PF06445 GyrI-like small molecule binding domain 128 282 1.6E-26 T 09-11-2016 IPR029442 GyrI-like small molecule binding domain CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 SUPERFAMILY SSF55136 128 285 3.14E-27 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 Gene3D G3DSA:1.10.10.60 59 116 1.4E-20 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 Gene3D G3DSA:1.10.10.60 1 58 5.5E-18 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 PANTHER PTHR11019 2 112 1.1E-45 T 09-11-2016 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 SMART SM00342 21 104 9.1E-26 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 Gene3D G3DSA:3.20.80.10 117 282 4.3E-25 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 Pfam PF12833 Helix-turn-helix domain 28 103 9.1E-17 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 3.4E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 3.4E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17580 5e6429020c409eba6a8678e3a2fb34fa 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 PANTHER PTHR33525:SF4 2 370 3.8E-135 T 09-11-2016 CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 SMART SM00052 1 198 1.7E-5 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 PANTHER PTHR33525 2 370 3.8E-135 T 09-11-2016 CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 Pfam PF00563 EAL domain 8 193 7.2E-18 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 PIRSF PIRSF003180 1 403 1.3E-121 T 09-11-2016 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 Gene3D G3DSA:1.10.3150.10 186 400 1.7E-28 T 09-11-2016 IPR013976 Metal-dependent hydrolase HDOD CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 SUPERFAMILY SSF141868 4 199 6.02E-29 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 Gene3D G3DSA:3.20.20.450 81 185 5.0E-16 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 Pfam PF08668 HDOD domain 205 322 5.6E-12 T 09-11-2016 IPR013976 Metal-dependent hydrolase HDOD CLOSPO_RS15575 6b9f0adf670a098f3e7114a8b7ca541f 403 SUPERFAMILY SSF109604 184 401 9.73E-37 T 09-11-2016 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 21 32 - T 09-11-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 Gene3D G3DSA:3.50.30.10 1 91 6.2E-34 T 09-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 SUPERFAMILY SSF51621 86 154 8.68E-16 T 09-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 Pfam PF00391 PEP-utilising enzyme, mobile domain 1 62 5.2E-21 T 09-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 88 155 4.9E-18 T 09-11-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 SUPERFAMILY SSF52009 1 82 2.09E-27 T 09-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 Gene3D G3DSA:3.20.20.60 92 155 2.4E-16 T 09-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CLOSPO_RS07215 0c38ad58efd55cf6f23bb5a85721d27f 155 PANTHER PTHR22931 1 155 3.2E-60 T 09-11-2016 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 SUPERFAMILY SSF53623 219 291 2.98E-35 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 SUPERFAMILY SSF53623 32 185 2.98E-35 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 Gene3D G3DSA:3.40.1190.10 218 292 6.4E-44 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 Gene3D G3DSA:3.40.1190.10 31 184 6.4E-44 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 Pfam PF08245 Mur ligase middle domain 45 274 4.4E-17 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 43 67 - T 09-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 PANTHER PTHR23135:SF7 248 432 1.1E-163 T 09-11-2016 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 PANTHER PTHR23135:SF7 21 218 1.1E-163 T 09-11-2016 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 PANTHER PTHR23135 248 432 1.1E-163 T 09-11-2016 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 PANTHER PTHR23135 21 218 1.1E-163 T 09-11-2016 CLOSPO_RS12595 c46ed793d9e2f53182d8c43ff5db838c 441 Pfam PF08353 Domain of unknown function (DUF1727) 314 424 1.1E-37 T 09-11-2016 IPR013564 Domain of unknown function DUF1727 CLOSPO_RS16660 18c4f0b07eb99319553a15ac4a90ffb4 316 PANTHER PTHR30465 5 312 2.5E-114 T 09-11-2016 CLOSPO_RS16660 18c4f0b07eb99319553a15ac4a90ffb4 316 Gene3D G3DSA:1.10.3720.10 95 301 7.0E-22 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16660 18c4f0b07eb99319553a15ac4a90ffb4 316 PANTHER PTHR30465:SF24 5 312 2.5E-114 T 09-11-2016 CLOSPO_RS16660 18c4f0b07eb99319553a15ac4a90ffb4 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 311 7.0E-41 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16660 18c4f0b07eb99319553a15ac4a90ffb4 316 SUPERFAMILY SSF161098 98 297 4.97E-19 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 Gene3D G3DSA:3.30.565.10 251 415 3.3E-35 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 3.7E-14 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 3.7E-14 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 3.7E-14 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 3.7E-14 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 SUPERFAMILY SSF47384 186 264 7.65E-12 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 SMART SM00387 309 419 3.4E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 PANTHER PTHR24423 132 415 2.5E-55 T 09-11-2016 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 PANTHER PTHR24423 1 11 2.5E-55 T 09-11-2016 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 Gene3D G3DSA:1.10.287.130 200 250 1.3E-9 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 SUPERFAMILY SSF55874 254 415 4.06E-34 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 SMART SM00388 198 264 7.0E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 264 2.8E-10 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17345 3fcd6df33759fad3dcf454c8035f6b41 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 416 7.5E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16860 39e6026012e55ac1478ae03fe781f65b 329 Pfam PF01497 Periplasmic binding protein 70 307 1.9E-28 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS16860 39e6026012e55ac1478ae03fe781f65b 329 PANTHER PTHR30532 1 329 7.1E-70 T 09-11-2016 CLOSPO_RS16860 39e6026012e55ac1478ae03fe781f65b 329 Gene3D G3DSA:3.40.50.1980 182 327 1.2E-22 T 09-11-2016 CLOSPO_RS16860 39e6026012e55ac1478ae03fe781f65b 329 SUPERFAMILY SSF53807 51 323 7.85E-48 T 09-11-2016 CLOSPO_RS16860 39e6026012e55ac1478ae03fe781f65b 329 PANTHER PTHR30532:SF1 1 329 7.1E-70 T 09-11-2016 CLOSPO_RS16860 39e6026012e55ac1478ae03fe781f65b 329 Gene3D G3DSA:3.40.50.1980 49 181 6.4E-24 T 09-11-2016 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SMART SM00488 190 437 1.4E-5 T 09-11-2016 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 PANTHER PTHR11472 194 784 3.3E-95 T 09-11-2016 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SUPERFAMILY SSF52540 159 298 4.55E-17 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SUPERFAMILY SSF52540 352 411 4.55E-17 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Gene3D G3DSA:3.40.50.300 588 758 4.3E-7 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Pfam PF06733 DEAD_2 287 406 2.8E-12 T 09-11-2016 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Pfam PF13307 Helicase C-terminal domain 600 765 7.5E-40 T 09-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SUPERFAMILY SSF52540 531 745 9.4E-15 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SUPERFAMILY SSF52540 212 268 9.4E-15 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SUPERFAMILY SSF52540 334 408 9.4E-15 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Gene3D G3DSA:3.40.50.300 193 299 5.4E-12 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Gene3D G3DSA:3.40.50.300 349 401 5.4E-12 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 SMART SM00491 616 752 1.6E-11 T 09-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Pfam PF12705 PD-(D/E)XK nuclease superfamily 69 156 1.5E-5 T 09-11-2016 CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Pfam PF06777 Helical and beta-bridge domain 497 585 7.8E-8 T 09-11-2016 IPR010643 Helical and beta-bridge domain CLOSPO_RS15905 6f0192c5234a26ca40815a2598d12a01 784 Pfam PF00270 DEAD/DEAH box helicase 210 286 9.7E-5 T 09-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOSPO_RS08035 f7f2e662be849bc3366882f30d511365 311 Gene3D G3DSA:3.30.830.10 2 121 8.5E-4 T 09-11-2016 IPR011237 Peptidase M16 domain GO:0046872 CLOSPO_RS08035 f7f2e662be849bc3366882f30d511365 311 PANTHER PTHR11851:SF68 1 311 5.3E-62 T 09-11-2016 CLOSPO_RS08035 f7f2e662be849bc3366882f30d511365 311 SUPERFAMILY SSF63411 147 303 1.42E-33 T 09-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOSPO_RS08035 f7f2e662be849bc3366882f30d511365 311 PANTHER PTHR11851 1 311 5.3E-62 T 09-11-2016 CLOSPO_RS08035 f7f2e662be849bc3366882f30d511365 311 SUPERFAMILY SSF63411 1 135 2.66E-33 T 09-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOSPO_RS08035 f7f2e662be849bc3366882f30d511365 311 Pfam PF08367 Peptidase M16C associated 1 76 1.6E-21 T 09-11-2016 IPR013578 Peptidase M16C associated GO:0006508 CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 Gene3D G3DSA:3.90.79.10 6 129 1.8E-36 T 09-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 PANTHER PTHR22769 1 189 3.1E-17 T 09-11-2016 CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 Pfam PF00293 NUDIX domain 8 103 3.9E-13 T 09-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 09-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 PANTHER PTHR22769:SF14 1 189 3.1E-17 T 09-11-2016 CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 PRINTS PR00502 NUDIX hydrolase family signature 33 47 7.9E-8 T 09-11-2016 IPR020476 NUDIX hydrolase CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 PRINTS PR00502 NUDIX hydrolase family signature 47 62 7.9E-8 T 09-11-2016 IPR020476 NUDIX hydrolase CLOSPO_RS15660 03c24c3c8f8a7bb29ad388ae6fdb0548 297 SUPERFAMILY SSF55811 5 105 2.3E-20 T 09-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 CLOSPO_RS14620 98d18fdf815361a9175a8830730d6d7e 351 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 351 1.3E-89 T 09-11-2016 IPR014227 Sporulation integral membrane protein YtvI CLOSPO_RS14620 98d18fdf815361a9175a8830730d6d7e 351 Pfam PF01594 Domain of unknown function DUF20 12 343 7.1E-46 T 09-11-2016 IPR002549 Transmembrane protein TqsA-like CLOSPO_RS14620 98d18fdf815361a9175a8830730d6d7e 351 PANTHER PTHR21716 1 351 5.5E-145 T 09-11-2016 IPR002549 Transmembrane protein TqsA-like CLOSPO_RS14620 98d18fdf815361a9175a8830730d6d7e 351 PANTHER PTHR21716:SF9 1 351 5.5E-145 T 09-11-2016 CLOSPO_RS16930 562529f6c733cca77574e70c99cd38e7 358 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 17 153 4.2E-25 T 09-11-2016 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019|UniPathway: UPA00964 CLOSPO_RS16930 562529f6c733cca77574e70c99cd38e7 358 Pfam PF16169 Domain of unknown function (DUF4872) 166 251 2.8E-9 T 09-11-2016 IPR032369 Domain of unknown function DUF4872 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 SUPERFAMILY SSF46548 122 237 1.05E-11 T 09-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 Pfam PF08331 Domain of unknown function (DUF1730) 54 123 1.0E-12 T 09-11-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700|UniPathway: UPA00392 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 PANTHER PTHR30002:SF4 1 302 8.4E-114 T 09-11-2016 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 176 187 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 Gene3D G3DSA:3.30.70.20 175 234 2.8E-5 T 09-11-2016 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 PANTHER PTHR30002 1 302 8.4E-114 T 09-11-2016 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 301 8.2E-77 T 09-11-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 CLOSPO_RS13670 58a756581ac6850181bcf3cf12061e21 321 Pfam PF13484 4Fe-4S double cluster binding domain 175 234 3.4E-11 T 09-11-2016 CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 Gene3D G3DSA:3.10.450.50 3 24 1.7E-8 T 09-11-2016 IPR032710 NTF2-like domain CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 SUPERFAMILY SSF55920 45 289 1.57E-76 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 Hamap MF_01974 Methionine aminopeptidase [map]. 45 291 35.313 T 09-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 Pfam PF00557 Metallopeptidase family M24 55 282 1.5E-49 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 Pfam PF02810 SEC-C motif 7 23 1.1E-9 T 09-11-2016 IPR004027 SEC-C motif CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 PANTHER PTHR10804:SF82 45 289 2.5E-114 T 09-11-2016 CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 Gene3D G3DSA:3.90.230.10 46 289 4.1E-85 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 SUPERFAMILY SSF103642 6 25 2.78E-7 T 09-11-2016 CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 202 214 1.4E-20 T 09-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 109 122 1.4E-20 T 09-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 233 245 1.4E-20 T 09-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 132 148 1.4E-20 T 09-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 PANTHER PTHR10804 45 289 2.5E-114 T 09-11-2016 CLOSPO_RS14990 77004b08736fac10966011e6a162fdeb 291 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 46 290 2.5E-82 T 09-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 SUPERFAMILY SSF58104 33 333 1.57E-58 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 PANTHER PTHR30290:SF14 342 822 2.5E-146 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 PANTHER PTHR30290:SF14 19 48 2.5E-146 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 Gene3D G3DSA:1.10.287.950 80 294 7.8E-47 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 Gene3D G3DSA:3.10.105.10 584 795 1.3E-44 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 Gene3D G3DSA:3.90.76.10 352 516 4.1E-43 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 117 309 6.1E-40 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 SUPERFAMILY SSF53850 339 820 1.3E-103 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 390 412 - T 09-11-2016 IPR023765 Solute-binding protein family 5, conserved site CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 384 745 2.9E-66 T 09-11-2016 IPR000914 Solute-binding protein family 5 domain CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 PANTHER PTHR30290 342 822 2.5E-146 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 PANTHER PTHR30290 19 48 2.5E-146 T 09-11-2016 CLOSPO_RS17480 7d4c1ef6cd8792cbdc14f1a7f7314277 825 SMART SM00283 63 324 1.2E-42 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 Gene3D G3DSA:3.40.640.10 141 356 5.8E-55 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 SUPERFAMILY SSF53383 70 466 1.24E-83 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 SUPERFAMILY SSF46785 4 83 1.29E-18 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 Gene3D G3DSA:1.10.10.10 3 76 3.6E-23 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 PANTHER PTHR11751 110 469 3.3E-210 T 09-11-2016 CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 Pfam PF00155 Aminotransferase class I and II 140 434 7.5E-22 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 SMART SM00345 16 75 1.0E-11 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 PANTHER PTHR11751:SF410 110 469 3.3E-210 T 09-11-2016 CLOSPO_RS16555 40dca8f5aaebe62e9a212dc251ed97af 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.6E-10 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS02855 feb13ebe16af77315bf2cc0104e1d0b7 98 PANTHER PTHR34265 1 98 3.1E-32 T 09-11-2016 CLOSPO_RS02855 feb13ebe16af77315bf2cc0104e1d0b7 98 SUPERFAMILY SSF53067 10 97 1.94E-25 T 09-11-2016 CLOSPO_RS02855 feb13ebe16af77315bf2cc0104e1d0b7 98 Pfam PF03309 Type III pantothenate kinase 1 92 1.2E-33 T 09-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 CLOSPO_RS02855 feb13ebe16af77315bf2cc0104e1d0b7 98 Gene3D G3DSA:3.30.420.40 2 95 3.3E-29 T 09-11-2016 CLOSPO_RS02855 feb13ebe16af77315bf2cc0104e1d0b7 98 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 1 97 1.5E-29 T 09-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 SMART SM00434 10 462 9.8E-288 T 09-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 548 3.8E-10 T 09-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 802 2.0E-10 T 09-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 701 1.7E-16 T 09-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 752 2.4E-10 T 09-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 553 597 5.0E-10 T 09-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 608 651 2.2E-8 T 09-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 SUPERFAMILY SSF56719 30 485 2.62E-184 T 09-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 806 29.999 T 09-11-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 PANTHER PTHR10169 3 772 0.0 T 09-11-2016 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Gene3D G3DSA:3.30.1360.40 235 329 9.8E-41 T 09-11-2016 IPR024946 Arginine repressor C-terminal-like domain CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 803 0.0 T 09-11-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 469 5.2E-163 T 09-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Gene3D G3DSA:3.90.199.10 33 215 4.6E-84 T 09-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 PANTHER PTHR10169:SF48 3 772 0.0 T 09-11-2016 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Gene3D G3DSA:2.120.10.90 494 803 8.6E-126 T 09-11-2016 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 Gene3D G3DSA:1.10.268.10 360 459 8.1E-39 T 09-11-2016 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS14515 142b5afb23099e848296d81c37d47f8b 846 SUPERFAMILY SSF101904 496 811 1.44E-109 T 09-11-2016 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 449 3.3E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 288 6.2E-10 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 Gene3D G3DSA:3.30.565.10 301 448 9.3E-47 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 SMART SM00388 230 294 8.2E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 7.7E-13 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 449 7.7E-13 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 7.7E-13 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 7.7E-13 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 Gene3D G3DSA:1.10.287.130 221 285 5.2E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 SUPERFAMILY SSF47384 214 293 1.24E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 PANTHER PTHR24423 170 448 1.1E-75 T 09-11-2016 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 PANTHER PTHR24423 85 128 1.1E-75 T 09-11-2016 CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 SUPERFAMILY SSF55874 305 448 1.44E-42 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18620 4ae20b2acf8dadc5264570e47a6ee436 454 SMART SM00387 341 452 2.8E-36 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16835 71dce54660ee54aefd4128a54e6cefa6 187 PANTHER PTHR30173 1 177 5.4E-25 T 09-11-2016 CLOSPO_RS16835 71dce54660ee54aefd4128a54e6cefa6 187 SUPERFAMILY SSF88659 109 177 2.06E-5 T 09-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS16835 71dce54660ee54aefd4128a54e6cefa6 187 Gene3D G3DSA:1.10.1740.10 3 103 1.8E-11 T 09-11-2016 CLOSPO_RS16835 71dce54660ee54aefd4128a54e6cefa6 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 177 7.0E-14 T 09-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS16835 71dce54660ee54aefd4128a54e6cefa6 187 Pfam PF04542 Sigma-70 region 2 24 92 8.8E-8 T 09-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS16835 71dce54660ee54aefd4128a54e6cefa6 187 SUPERFAMILY SSF88946 4 104 3.92E-12 T 09-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 PANTHER PTHR30007 1 250 1.5E-30 T 09-11-2016 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 Gene3D G3DSA:3.20.20.140 165 261 1.8E-38 T 09-11-2016 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 Gene3D G3DSA:3.20.20.140 1 86 1.8E-38 T 09-11-2016 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 PANTHER PTHR30007:SF4 1 250 1.5E-30 T 09-11-2016 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 Gene3D G3DSA:1.10.268.10 87 164 7.6E-4 T 09-11-2016 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 SMART SM00481 4 69 1.3E-14 T 09-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 Pfam PF02811 PHP domain 5 145 3.1E-10 T 09-11-2016 IPR004013 PHP domain GO:0003824 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 SUPERFAMILY SSF89550 168 260 1.57E-43 T 09-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 CLOSPO_RS16735 dae54d160e1e8b8305eff6b51fa792b6 272 SUPERFAMILY SSF89550 1 84 1.57E-43 T 09-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 Pfam PF13411 MerR HTH family regulatory protein 5 69 2.8E-14 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 PANTHER PTHR30204:SF20 1 273 5.6E-120 T 09-11-2016 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 SMART SM00871 122 271 1.2E-9 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 PANTHER PTHR30204 1 273 5.6E-120 T 09-11-2016 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 Gene3D G3DSA:1.10.1660.10 1 59 4.3E-23 T 09-11-2016 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 Gene3D G3DSA:1.10.1660.10 60 114 7.9E-6 T 09-11-2016 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 SUPERFAMILY SSF46955 4 111 1.83E-27 T 09-11-2016 IPR009061 Putative DNA-binding domain CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 SMART SM00422 5 75 1.6E-12 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 Pfam PF06445 GyrI-like small molecule binding domain 124 269 2.3E-8 T 09-11-2016 IPR029442 GyrI-like small molecule binding domain CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 Gene3D G3DSA:3.20.80.10 121 272 5.7E-45 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS18525 9cf85024707c28edb952f142fb152f6d 273 SUPERFAMILY SSF55136 125 269 2.28E-24 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 419 4.0E-51 T 09-11-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 Gene3D G3DSA:3.40.50.720 5 168 2.2E-64 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 Pfam PF02056 Family 4 glycosyl hydrolase 8 187 2.2E-62 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 09-11-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 SUPERFAMILY SSF51735 6 166 8.67E-54 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PANTHER PTHR32092 4 444 0.0 T 09-11-2016 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 Gene3D G3DSA:3.90.110.10 170 443 2.7E-102 T 09-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 SUPERFAMILY SSF56327 171 444 2.49E-90 T 09-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 8 23 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 1.1E-55 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13180 b11b5357f7e5d95a5c9b42dd97af4f9b 444 PANTHER PTHR32092:SF7 4 444 0.0 T 09-11-2016 CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 Gene3D G3DSA:3.40.50.300 3 234 3.8E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 SMART SM00382 33 215 3.7E-8 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 PANTHER PTHR24220:SF141 10 250 2.5E-128 T 09-11-2016 CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 Pfam PF00005 ABC transporter 24 167 3.9E-28 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 PANTHER PTHR24220 10 250 2.5E-128 T 09-11-2016 CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17275 a328ae9feef760b9cf4e6050115d1191 262 SUPERFAMILY SSF52540 6 230 1.41E-58 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17690 4956a66727a1351f03d2150b599ccc34 151 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 147 3.5E-37 T 09-11-2016 IPR006750 Putative inner membrane exporter, YdcZ CLOSPO_RS17690 4956a66727a1351f03d2150b599ccc34 151 PANTHER PTHR34821:SF2 1 149 1.1E-48 T 09-11-2016 CLOSPO_RS17690 4956a66727a1351f03d2150b599ccc34 151 PANTHER PTHR34821 1 149 1.1E-48 T 09-11-2016 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 Pfam PF00704 Glycosyl hydrolases family 18 38 340 2.4E-29 T 09-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 SUPERFAMILY SSF51445 33 348 3.13E-58 T 09-11-2016 IPR017853 Glycoside hydrolase superfamily CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 PANTHER PTHR11177:SF195 7 237 1.2E-159 T 09-11-2016 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 PANTHER PTHR11177:SF195 286 355 1.2E-159 T 09-11-2016 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 ProSitePatterns PS01095 Chitinases family 18 active site. 139 147 - T 09-11-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 PANTHER PTHR11177 7 237 1.2E-159 T 09-11-2016 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 PANTHER PTHR11177 286 355 1.2E-159 T 09-11-2016 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 SMART SM00636 36 340 1.1E-6 T 09-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 CLOSPO_RS18810 3db82f0e54a4d6fa7283426ba6b15f7f 355 Gene3D G3DSA:3.20.20.80 31 348 6.3E-69 T 09-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 ProSitePatterns PS01265 Tpx family signature. 81 92 - T 09-11-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 PANTHER PTHR10681:SF81 2 164 8.4E-52 T 09-11-2016 CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 PANTHER PTHR10681 2 164 8.4E-52 T 09-11-2016 CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 SUPERFAMILY SSF52833 3 158 2.07E-40 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 Hamap MF_00269 Probable thiol peroxidase [tpx]. 2 161 35.044 T 09-11-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 Gene3D G3DSA:3.40.30.10 2 163 7.5E-47 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS15855 37cbd296aff1c0f1c2783dd2a3c92812 164 Pfam PF00578 AhpC/TSA family 19 140 2.2E-20 T 09-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 859 0.0 T 09-11-2016 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Gene3D G3DSA:3.40.1190.10 474 711 1.5E-39 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Pfam PF08443 RimK-like ATP-grasp domain 384 452 1.2E-4 T 09-11-2016 IPR013651 ATP-grasp fold, RimK-type CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Pfam PF08443 RimK-like ATP-grasp domain 212 315 7.0E-8 T 09-11-2016 IPR013651 ATP-grasp fold, RimK-type CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 SUPERFAMILY SSF53623 441 728 1.2E-45 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 PANTHER PTHR23135:SF18 383 869 1.3E-259 T 09-11-2016 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 SUPERFAMILY SSF53244 717 845 8.24E-25 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Pfam PF02875 Mur ligase family, glutamate ligase domain 717 791 6.9E-10 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Gene3D G3DSA:3.30.470.20 207 331 6.4E-28 T 09-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Gene3D G3DSA:3.30.470.20 392 473 6.4E-28 T 09-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Pfam PF08245 Mur ligase middle domain 482 692 2.4E-30 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 PANTHER PTHR23135 383 869 1.3E-259 T 09-11-2016 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 SUPERFAMILY SSF56059 213 486 3.2E-31 T 09-11-2016 CLOSPO_RS14125 8690a2f437186e55c47a4948d1d2ba51 873 Gene3D G3DSA:3.90.190.20 719 845 1.8E-24 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 SUPERFAMILY SSF75620 1 322 2.75E-126 T 09-11-2016 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 PANTHER PTHR11075 1 322 4.1E-153 T 09-11-2016 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 SMART SM00937 45 154 2.8E-52 T 09-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 Gene3D G3DSA:3.30.160.20 187 265 2.7E-36 T 09-11-2016 IPR014720 Double-stranded RNA-binding domain CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 322 2.5E-147 T 09-11-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 Pfam PF00472 RF-1 domain 188 297 4.0E-41 T 09-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 204 220 - T 09-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 Gene3D G3DSA:1.20.58.410 1 74 3.0E-18 T 09-11-2016 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 PANTHER PTHR11075:SF6 1 322 4.1E-153 T 09-11-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS13840 094489c514caee26c694c5de9b22cc7c 325 Pfam PF03462 PCRF domain 1 179 6.7E-58 T 09-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CLOSPO_RS06115 de59fbccb27c45ced7e159828be22a63 60 Gene3D G3DSA:3.40.50.620 3 49 1.2E-7 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 SMART SM00357 109 174 3.4E-14 T 09-11-2016 IPR011129 Cold shock protein GO:0003676 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Gene3D G3DSA:3.40.50.300 187 471 3.5E-91 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 PANTHER PTHR15184 32 450 3.6E-172 T 09-11-2016 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Pfam PF07497 Rho termination factor, RNA-binding domain 109 181 1.0E-31 T 09-11-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Pfam PF07498 Rho termination factor, N-terminal domain 5 43 5.0E-12 T 09-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 SUPERFAMILY SSF68912 5 42 1.57E-6 T 09-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 474 189.232 T 09-11-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 SUPERFAMILY SSF52540 146 424 1.97E-63 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 SMART SM00959 5 47 1.4E-12 T 09-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 SMART SM00382 223 408 4.3E-9 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Gene3D G3DSA:2.40.50.140 103 182 2.5E-43 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Gene3D G3DSA:2.40.50.140 4 45 2.5E-43 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 472 7.1E-178 T 09-11-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 213 416 1.4E-18 T 09-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 PANTHER PTHR15184:SF34 32 450 3.6E-172 T 09-11-2016 CLOSPO_RS14055 6a2ac09458984acea8335510207e2607 481 SUPERFAMILY SSF50249 101 170 2.63E-6 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 Gene3D G3DSA:3.60.40.10 707 789 7.2E-10 T 09-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 SUPERFAMILY SSF81606 590 788 1.12E-15 T 09-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 34 792 0.0 T 09-11-2016 IPR014221 Sporulation stage II, protein E KEGG: 04660+3.1.3.16 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 PANTHER PTHR21021:SF22 59 68 1.3E-30 T 09-11-2016 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 PANTHER PTHR21021:SF22 568 791 1.3E-30 T 09-11-2016 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 PANTHER PTHR21021:SF22 536 552 1.3E-30 T 09-11-2016 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 606 791 2.5E-30 T 09-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 PANTHER PTHR21021 536 552 1.3E-30 T 09-11-2016 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 SMART SM00331 578 791 3.0E-26 T 09-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 PANTHER PTHR21021 568 791 1.3E-30 T 09-11-2016 CLOSPO_RS15260 28835a4ef11420712d032b94a0535894 795 PANTHER PTHR21021 59 68 1.3E-30 T 09-11-2016 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 PANTHER PTHR21091 1 209 3.1E-73 T 09-11-2016 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 Gene3D G3DSA:3.30.950.10 113 231 3.1E-34 T 09-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 SUPERFAMILY SSF53790 3 249 1.57E-66 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 09-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 PANTHER PTHR21091:SF17 1 209 3.1E-73 T 09-11-2016 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 5 249 1.4E-101 T 09-11-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 209 8.5E-45 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18145 8bbf4e067dc86b0b8ba837f0ba529f58 252 Gene3D G3DSA:3.40.1010.10 3 112 1.8E-33 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS17505 8b143874210c367509522216a1a838fc 523 Pfam PF04294 VanW like protein 245 374 4.7E-51 T 09-11-2016 IPR007391 Vancomycin resistance VanW CLOSPO_RS17505 8b143874210c367509522216a1a838fc 523 PANTHER PTHR35788 3 459 2.4E-182 T 09-11-2016 CLOSPO_RS17505 8b143874210c367509522216a1a838fc 523 PANTHER PTHR35788:SF1 3 459 2.4E-182 T 09-11-2016 CLOSPO_RS17505 8b143874210c367509522216a1a838fc 523 SMART SM01208 382 459 2.9E-17 T 09-11-2016 IPR011098 G5 domain CLOSPO_RS17505 8b143874210c367509522216a1a838fc 523 Pfam PF07501 G5 domain 391 458 1.7E-12 T 09-11-2016 IPR011098 G5 domain CLOSPO_RS17505 8b143874210c367509522216a1a838fc 523 Pfam PF12229 Putative peptidoglycan binding domain 94 205 1.4E-20 T 09-11-2016 IPR022029 Putative peptidoglycan binding domain CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 TIGRFAM TIGR01069 mutS2: MutS2 family protein 3 577 1.0E-180 T 09-11-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 Gene3D G3DSA:3.40.50.300 284 505 3.9E-63 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 PANTHER PTHR11361 9 577 3.5E-237 T 09-11-2016 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 SMART SM00534 320 505 1.2E-76 T 09-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 SMART SM00533 4 307 2.0E-21 T 09-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 SUPERFAMILY SSF52540 284 505 6.71E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 PANTHER PTHR11361:SF14 9 577 3.5E-237 T 09-11-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 402 418 - T 09-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 Pfam PF00488 MutS domain V 324 504 1.0E-36 T 09-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS08990 a96a84916f8a61517e9ea06048f16123 577 SUPERFAMILY SSF48334 58 282 1.7E-16 T 09-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 Gene3D G3DSA:3.40.50.300 269 486 1.3E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 PANTHER PTHR10285 200 492 4.9E-131 T 09-11-2016 CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 SUPERFAMILY SSF55186 68 236 3.92E-36 T 09-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 291 486 2.3E-17 T 09-11-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 PANTHER PTHR10285:SF45 200 492 4.9E-131 T 09-11-2016 CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 SUPERFAMILY SSF52540 284 484 1.54E-21 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13725 3aec2a613181fe6f12f81083d313fa98 552 Gene3D G3DSA:3.30.980.10 69 161 1.7E-18 T 09-11-2016 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Pfam PF00575 S1 RNA binding domain 646 717 8.1E-21 T 09-11-2016 IPR003029 S1 domain GO:0003676 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Pfam PF12836 Helix-hairpin-helix motif 482 546 7.4E-30 T 09-11-2016 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SUPERFAMILY SSF158832 1 308 1.07E-111 T 09-11-2016 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Gene3D G3DSA:1.10.3500.10 109 309 5.5E-95 T 09-11-2016 IPR023323 Tex-like domain CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Gene3D G3DSA:1.10.3500.10 442 489 5.5E-95 T 09-11-2016 IPR023323 Tex-like domain CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Gene3D G3DSA:1.10.10.650 1 108 4.8E-41 T 09-11-2016 IPR023319 Tex-like protein, HTH domain CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Gene3D G3DSA:3.30.420.140 313 441 5.0E-50 T 09-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 PANTHER PTHR10724:SF1 1 718 0.0 T 09-11-2016 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SUPERFAMILY SSF47781 551 629 3.0E-16 T 09-11-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Pfam PF09371 Tex-like protein N-terminal domain 8 192 2.2E-68 T 09-11-2016 IPR018974 Tex-like protein, N-terminal CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SUPERFAMILY SSF47781 461 547 1.22E-27 T 09-11-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SMART SM00732 313 415 1.2E-35 T 09-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Gene3D G3DSA:1.10.150.310 490 627 7.6E-46 T 09-11-2016 IPR023097 Tex RuvX-like domain CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SMART SM00316 646 717 2.5E-28 T 09-11-2016 IPR022967 RNA-binding domain, S1 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Pfam PF16921 Tex protein YqgF-like domain 313 442 2.2E-52 T 09-11-2016 IPR032639 Tex protein, YqgF-like domain CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 Gene3D G3DSA:2.40.50.140 641 718 7.2E-30 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 PANTHER PTHR10724 1 718 0.0 T 09-11-2016 CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SUPERFAMILY SSF50249 632 718 8.24E-27 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13830 dd239d4869df04e4af647d8f7965d98c 718 SUPERFAMILY SSF53098 309 460 1.74E-49 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS14610 7e01bb7598a1d4ab0905ce89aa1db8a8 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 2 73 4.9E-12 T 09-11-2016 IPR005370 Uncharacterised protein family UPF0180 CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 5 108 6.0E-8 T 09-11-2016 IPR026466 Fimbrial isopeptide formation D2 domain CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 PANTHER PTHR34819 1 269 7.7E-51 T 09-11-2016 CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 131 166 6.4E-8 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2 50 2.6E-17 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 Pfam PF01345 Domain of unknown function DUF11 113 165 6.2E-10 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 Pfam PF01345 Domain of unknown function DUF11 2 44 1.3E-9 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS06455 37fbdb2ca17290678b822e344561243e 269 PANTHER PTHR34819:SF3 1 269 7.7E-51 T 09-11-2016 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 PANTHER PTHR26402:SF405 2 219 2.1E-100 T 09-11-2016 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 Gene3D G3DSA:3.40.50.2300 1 125 1.2E-39 T 09-11-2016 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 PANTHER PTHR26402 2 219 2.1E-100 T 09-11-2016 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 SUPERFAMILY SSF52172 1 179 4.13E-42 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 1.5E-19 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 SMART SM00448 2 113 2.7E-38 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 Gene3D G3DSA:1.10.10.10 126 221 1.8E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 SMART SM00862 146 220 9.6E-16 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17900 3a427a535ddc0fc2f5ba93de4b287e4a 223 Pfam PF00072 Response regulator receiver domain 4 113 9.3E-30 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 SUPERFAMILY SSF55681 121 422 3.5E-74 T 09-11-2016 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 418 2.4E-124 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 Gene3D G3DSA:3.30.930.10 110 421 9.1E-106 T 09-11-2016 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 225 401 2.1E-26 T 09-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 Gene3D G3DSA:1.10.287.40 1 109 1.9E-26 T 09-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 111 1.6E-27 T 09-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PRINTS PR00981 Seryl-tRNA synthetase signature 267 279 1.8E-20 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PRINTS PR00981 Seryl-tRNA synthetase signature 319 332 1.8E-20 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PRINTS PR00981 Seryl-tRNA synthetase signature 279 292 1.8E-20 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PRINTS PR00981 Seryl-tRNA synthetase signature 336 352 1.8E-20 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.8E-20 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PANTHER PTHR11778 1 424 1.8E-159 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 SUPERFAMILY SSF46589 1 117 5.75E-25 T 09-11-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 CLOSPO_RS15900 8c10c289b874d0ccdb3aeca13b739f40 425 PIRSF PIRSF001529 1 425 6.7E-131 T 09-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 CLOSPO_RS18670 02437b186cd81a6620cee1ed6d411938 78 Pfam PF09851 Short C-terminal domain 51 74 6.9E-7 T 09-11-2016 IPR018649 SHOCT domain CLOSPO_RS15105 8d5903cf76ae7d9db8c1d1eee2b59882 196 Gene3D G3DSA:3.40.50.1000 46 195 5.2E-35 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS15105 8d5903cf76ae7d9db8c1d1eee2b59882 196 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 42 168 1.6E-13 T 09-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CLOSPO_RS15105 8d5903cf76ae7d9db8c1d1eee2b59882 196 PANTHER PTHR18901 1 195 4.2E-69 T 09-11-2016 CLOSPO_RS15105 8d5903cf76ae7d9db8c1d1eee2b59882 196 PANTHER PTHR18901:SF44 1 195 4.2E-69 T 09-11-2016 CLOSPO_RS15105 8d5903cf76ae7d9db8c1d1eee2b59882 196 Pfam PF13419 Haloacid dehalogenase-like hydrolase 30 168 3.1E-22 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS15105 8d5903cf76ae7d9db8c1d1eee2b59882 196 SUPERFAMILY SSF56784 15 194 3.05E-31 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS14250 2062483287efc5aa83e2e9ef30118622 145 Pfam PF01391 Collagen triple helix repeat (20 copies) 19 75 2.0E-9 T 09-11-2016 IPR008160 Collagen triple helix repeat CLOSPO_RS14250 2062483287efc5aa83e2e9ef30118622 145 PANTHER PTHR24023 19 145 6.2E-28 T 09-11-2016 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 Gene3D G3DSA:1.10.10.10 156 235 5.2E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 200 215 1.1E-8 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 200 1.1E-8 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 Pfam PF13545 Crp-like helix-turn-helix domain 160 233 1.1E-17 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 PANTHER PTHR24567 10 236 4.0E-92 T 09-11-2016 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 SMART SM00419 178 227 2.4E-12 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 Gene3D G3DSA:2.60.120.10 16 153 3.3E-37 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 SMART SM00100 20 139 7.2E-26 T 09-11-2016 IPR000595 Cyclic nucleotide-binding domain CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 PANTHER PTHR24567:SF32 10 236 4.0E-92 T 09-11-2016 CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 SUPERFAMILY SSF46785 158 235 3.18E-17 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 Pfam PF00027 Cyclic nucleotide-binding domain 40 126 1.8E-21 T 09-11-2016 IPR000595 Cyclic nucleotide-binding domain CLOSPO_RS16740 d2ec2883f826974b4a9aa0defe7d64f1 236 SUPERFAMILY SSF51206 15 154 7.59E-37 T 09-11-2016 IPR018490 Cyclic nucleotide-binding-like CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 146 4.6E-57 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 SUPERFAMILY SSF63411 1 146 5.86E-62 T 09-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 145 7.0E-49 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PANTHER PTHR35799 2 150 1.8E-96 T 09-11-2016 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 Gene3D G3DSA:3.30.1360.80 1 147 8.0E-65 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 148 35.514 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PIRSF PIRSF006160 1 150 3.6E-65 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 5.2E-40 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 73 91 5.2E-40 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 5.2E-40 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 5.2E-40 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17065 c9666de15b63c5e90f4dcd82f5dc3e23 150 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 5.2E-40 T 09-11-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOSPO_RS17295 60fc33e8bbf5eccf3b2a6e973c6a0b6b 263 Pfam PF12730 ABC-2 family transporter protein 4 203 5.1E-15 T 09-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 CLOSPO_RS18235 193bd5a2ffb5dfc4ab6b3a0bc1487063 341 SUPERFAMILY SSF50965 150 319 2.09E-6 T 09-11-2016 IPR011043 Galactose oxidase/kelch, beta-propeller CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 Gene3D G3DSA:1.10.10.10 122 216 2.1E-27 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 SUPERFAMILY SSF52172 1 126 2.28E-40 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 SUPERFAMILY SSF46894 122 216 9.28E-26 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 PANTHER PTHR26402:SF614 2 216 3.4E-81 T 09-11-2016 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 Gene3D G3DSA:3.40.50.2300 2 119 2.2E-39 T 09-11-2016 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 PANTHER PTHR26402 2 216 3.4E-81 T 09-11-2016 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 SMART SM00862 143 215 8.9E-23 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 Pfam PF00072 Response regulator receiver domain 4 112 5.8E-28 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 4.8E-22 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS16620 41af04fe21c80830fc77901b02fbb170 217 SMART SM00448 2 111 1.9E-44 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 177 19.122 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PANTHER PTHR11910 1 179 5.1E-42 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 173 4.7E-39 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 09-11-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 SUPERFAMILY SSF47928 2 105 1.31E-22 T 09-11-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 SUPERFAMILY SSF160527 72 177 5.75E-5 T 09-11-2016 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PANTHER PTHR11910:SF1 1 179 5.1E-42 T 09-11-2016 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 174 9.9E-47 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PRINTS PR00125 ATP synthase delta subunit signature 150 168 1.2E-21 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PRINTS PR00125 ATP synthase delta subunit signature 135 150 1.2E-21 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PRINTS PR00125 ATP synthase delta subunit signature 5 24 1.2E-21 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.2E-21 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.2E-21 T 09-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 CLOSPO_RS13960 fd25bf900cd592d619b0eac31fa5cf19 179 Gene3D G3DSA:1.10.520.20 5 105 3.0E-19 T 09-11-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain CLOSPO_RS12785 46ecd86c7efb54aed99224bc704dc8f2 130 Pfam PF07009 NusG domain II 12 121 9.0E-34 T 09-11-2016 IPR024045 NusG, domain 2 CLOSPO_RS12785 46ecd86c7efb54aed99224bc704dc8f2 130 Gene3D G3DSA:2.60.320.10 36 120 4.6E-22 T 09-11-2016 IPR024045 NusG, domain 2 CLOSPO_RS12785 46ecd86c7efb54aed99224bc704dc8f2 130 PANTHER PTHR40451 1 130 6.2E-37 T 09-11-2016 CLOSPO_RS12785 46ecd86c7efb54aed99224bc704dc8f2 130 PANTHER PTHR40451:SF1 1 130 6.2E-37 T 09-11-2016 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 500 4.1E-256 T 09-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Gene3D G3DSA:2.40.30.20 1 93 2.5E-37 T 09-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Gene3D G3DSA:3.40.50.300 95 371 5.5E-117 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 SUPERFAMILY SSF52540 96 370 1.01E-99 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 09-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 SUPERFAMILY SSF50615 10 94 4.71E-30 T 09-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Gene3D G3DSA:1.20.150.20 372 500 4.1E-54 T 09-11-2016 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 PANTHER PTHR15184:SF3 1 485 4.1E-303 T 09-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 PIRSF PIRSF039088 1 503 2.7E-256 T 09-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.6E-73 T 09-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 5.4E-18 T 09-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 8.2E-51 T 09-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 SUPERFAMILY SSF47917 372 500 1.52E-47 T 09-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 PANTHER PTHR15184 1 485 4.1E-303 T 09-11-2016 CLOSPO_RS13955 3e3538060ad5284e6ad3b332edc10d23 504 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 501 51.982 T 09-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS15420 8d91f0191590a1e7c82b14983fe7eed9 287 SUPERFAMILY SSF56281 38 285 4.46E-63 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15420 8d91f0191590a1e7c82b14983fe7eed9 287 PANTHER PTHR30619:SF1 32 285 1.5E-95 T 09-11-2016 CLOSPO_RS15420 8d91f0191590a1e7c82b14983fe7eed9 287 PANTHER PTHR30619 32 285 1.5E-95 T 09-11-2016 CLOSPO_RS15420 8d91f0191590a1e7c82b14983fe7eed9 287 Gene3D G3DSA:3.60.15.10 37 285 7.0E-51 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15420 8d91f0191590a1e7c82b14983fe7eed9 287 SMART SM00849 50 244 4.0E-13 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15420 8d91f0191590a1e7c82b14983fe7eed9 287 Pfam PF00753 Metallo-beta-lactamase superfamily 48 243 5.2E-22 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 PANTHER PTHR26402:SF50 4 232 4.6E-115 T 09-11-2016 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 SUPERFAMILY SSF52172 4 126 4.13E-43 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 SMART SM00862 154 230 5.4E-27 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 PANTHER PTHR26402 4 232 4.6E-115 T 09-11-2016 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 Gene3D G3DSA:1.10.10.10 131 231 6.9E-37 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 Pfam PF00072 Response regulator receiver domain 6 114 6.3E-32 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 SMART SM00448 4 114 2.1E-46 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 3.5E-27 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 Gene3D G3DSA:3.40.50.2300 4 128 5.3E-43 T 09-11-2016 CLOSPO_RS12840 2bca2b5462e9d22bfff5210602ec52b2 232 SUPERFAMILY SSF46894 129 230 2.55E-31 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS17390 10774eb8afe756c4e9fa3c0911586067 352 Gene3D G3DSA:1.10.10.10 35 89 1.4E-7 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17390 10774eb8afe756c4e9fa3c0911586067 352 Pfam PF08279 HTH domain 34 87 5.0E-7 T 09-11-2016 IPR013196 Helix-turn-helix, type 11 CLOSPO_RS17390 10774eb8afe756c4e9fa3c0911586067 352 PANTHER PTHR34580 21 346 9.7E-50 T 09-11-2016 CLOSPO_RS17390 10774eb8afe756c4e9fa3c0911586067 352 PIRSF PIRSF016838 27 344 5.3E-16 T 09-11-2016 IPR028349 Protein PafC CLOSPO_RS17390 10774eb8afe756c4e9fa3c0911586067 352 PANTHER PTHR34580:SF3 21 346 9.7E-50 T 09-11-2016 CLOSPO_RS17390 10774eb8afe756c4e9fa3c0911586067 352 Pfam PF13280 WYL domain 168 336 1.3E-41 T 09-11-2016 IPR026881 WYL domain CLOSPO_RS17270 595be8cff7165afdbb8169c16080bcd2 154 PANTHER PTHR36007:SF2 1 154 2.2E-95 T 09-11-2016 CLOSPO_RS17270 595be8cff7165afdbb8169c16080bcd2 154 PANTHER PTHR36007 1 154 2.2E-95 T 09-11-2016 CLOSPO_RS17270 595be8cff7165afdbb8169c16080bcd2 154 Pfam PF06695 Putative small multi-drug export protein 17 142 8.7E-44 T 09-11-2016 IPR009577 Putative small multi-drug export CLOSPO_RS18490 5927913b92a988184ac339bfa0bbd4dd 194 SMART SM00793 4 188 2.4E-5 T 09-11-2016 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CLOSPO_RS18490 5927913b92a988184ac339bfa0bbd4dd 194 Pfam PF04647 Accessory gene regulator B 6 181 4.1E-42 T 09-11-2016 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 PANTHER PTHR32071 33 470 1.5E-243 T 09-11-2016 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 09-11-2016 IPR025944 Sigma-54 interaction domain, conserved site CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 Gene3D G3DSA:3.40.50.300 148 325 1.8E-53 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 Gene3D G3DSA:3.30.450.20 27 129 1.3E-4 T 09-11-2016 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 Pfam PF02954 Bacterial regulatory protein, Fis family 417 457 1.4E-12 T 09-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 SUPERFAMILY SSF46689 366 460 7.62E-15 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 Pfam PF00158 Sigma-54 interaction domain 152 319 8.3E-69 T 09-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 Gene3D G3DSA:1.10.10.60 416 460 3.3E-16 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 SUPERFAMILY SSF52540 151 394 2.48E-67 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 PANTHER PTHR32071:SF27 33 470 1.5E-243 T 09-11-2016 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 SUPERFAMILY SSF55785 28 129 3.14E-5 T 09-11-2016 IPR000014 PAS domain CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 440 7.9E-8 T 09-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 440 460 7.9E-8 T 09-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 239 254 - T 09-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 Gene3D G3DSA:1.10.8.60 326 403 6.1E-20 T 09-11-2016 CLOSPO_RS16325 2077705ef709f9ec3c0a4a5eb35d1fcc 470 SMART SM00382 172 324 8.6E-6 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16485 8242d7d17c75009c73dd0fbb7f19442a 156 Gene3D G3DSA:3.40.630.30 1 152 4.8E-28 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16485 8242d7d17c75009c73dd0fbb7f19442a 156 PANTHER PTHR23091 1 152 2.3E-24 T 09-11-2016 CLOSPO_RS16485 8242d7d17c75009c73dd0fbb7f19442a 156 SUPERFAMILY SSF55729 1 151 1.58E-27 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16485 8242d7d17c75009c73dd0fbb7f19442a 156 PANTHER PTHR23091:SF122 1 152 2.3E-24 T 09-11-2016 CLOSPO_RS16485 8242d7d17c75009c73dd0fbb7f19442a 156 Pfam PF13673 Acetyltransferase (GNAT) domain 22 148 2.7E-13 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070 6 174 0.0 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 479 6.7E-79 T 09-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070 914 1270 0.0 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070:SF14 310 421 0.0 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Gene3D G3DSA:3.90.320.10 1056 1276 2.6E-33 T 09-11-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 3 1278 18.74 T 09-11-2016 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070 310 421 0.0 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070 572 881 0.0 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Gene3D G3DSA:1.10.486.10 649 820 1.2E-26 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070:SF14 914 1270 0.0 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Gene3D G3DSA:3.40.50.300 345 481 6.8E-69 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Gene3D G3DSA:3.40.50.300 5 163 6.8E-69 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Pfam PF13361 UvrD-like helicase C-terminal domain 490 936 3.7E-34 T 09-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52980 1067 1272 3.0E-39 T 09-11-2016 IPR011335 Restriction endonuclease type II-like CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Gene3D G3DSA:3.40.50.300 494 642 1.0E-81 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Gene3D G3DSA:3.40.50.300 834 992 1.0E-81 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070:SF14 6 174 0.0 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070:SF14 447 549 0.0 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070:SF14 572 881 0.0 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 450 1277 3.0E-263 T 09-11-2016 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 PANTHER PTHR11070 447 549 0.0 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1102 1264 4.3E-11 T 09-11-2016 CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52540 335 420 1.33E-111 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52540 449 519 1.33E-111 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52540 726 873 1.33E-111 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52540 915 941 1.33E-111 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52540 549 691 1.33E-111 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15510 cc350d74418eb07bd45bb3b25594112d 1279 SUPERFAMILY SSF52540 4 175 1.33E-111 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 SUPERFAMILY SSF54001 119 292 5.56E-15 T 09-11-2016 CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 PANTHER PTHR11039 5 340 1.3E-16 T 09-11-2016 CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 Pfam PF16472 Domain of unknown function (DUF5050) 327 390 1.6E-8 T 09-11-2016 IPR032485 Domain of unknown function DUF5050 CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 Gene3D G3DSA:2.120.10.30 289 361 8.5E-8 T 09-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 PANTHER PTHR11039:SF44 5 340 1.3E-16 T 09-11-2016 CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 SUPERFAMILY SSF63825 424 461 2.88E-5 T 09-11-2016 CLOSPO_RS12740 fff0a56de18666ca0b61041e973665c2 503 SUPERFAMILY SSF63825 292 361 2.88E-5 T 09-11-2016 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 SUPERFAMILY SSF53850 92 294 1.63E-30 T 09-11-2016 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 Gene3D G3DSA:3.40.190.10 196 266 1.9E-12 T 09-11-2016 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.1E-8 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.1E-8 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.1E-8 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 SUPERFAMILY SSF46785 1 112 3.59E-21 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 PANTHER PTHR30126 2 295 4.9E-111 T 09-11-2016 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 Gene3D G3DSA:3.40.190.10 90 195 2.3E-15 T 09-11-2016 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.4E-18 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 PANTHER PTHR30126:SF13 2 295 4.9E-111 T 09-11-2016 CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 Pfam PF03466 LysR substrate binding domain 91 294 1.7E-31 T 09-11-2016 IPR005119 LysR, substrate-binding CLOSPO_RS17695 846df311d6064f84203aaa8cf1c66763 295 Gene3D G3DSA:1.10.10.10 3 82 5.5E-23 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17740 7f8e37e5c40ee6ab1468277d88c07c7c 172 Pfam PF00881 Nitroreductase family 8 60 3.8E-12 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS17740 7f8e37e5c40ee6ab1468277d88c07c7c 172 Pfam PF00881 Nitroreductase family 67 146 4.3E-11 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS17740 7f8e37e5c40ee6ab1468277d88c07c7c 172 PANTHER PTHR23026 1 172 1.8E-110 T 09-11-2016 CLOSPO_RS17740 7f8e37e5c40ee6ab1468277d88c07c7c 172 Gene3D G3DSA:3.40.109.10 1 172 2.0E-49 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS17740 7f8e37e5c40ee6ab1468277d88c07c7c 172 SUPERFAMILY SSF55469 1 172 4.45E-49 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS17740 7f8e37e5c40ee6ab1468277d88c07c7c 172 PANTHER PTHR23026:SF106 1 172 1.8E-110 T 09-11-2016 CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 Gene3D G3DSA:1.10.8.60 425 481 1.1E-7 T 09-11-2016 CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 287 415 4.3E-28 T 09-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 Gene3D G3DSA:3.40.50.300 251 424 2.8E-41 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 SMART SM00382 283 418 2.7E-14 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 PANTHER PTHR23077 220 526 1.5E-170 T 09-11-2016 CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 SUPERFAMILY SSF52540 250 482 1.88E-50 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 PANTHER PTHR23077:SF75 220 526 1.5E-170 T 09-11-2016 CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 SUPERFAMILY SSF52540 77 232 4.72E-5 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 PANTHER PTHR23077 166 200 1.5E-170 T 09-11-2016 CLOSPO_RS18445 da7a4bc3a87db0bca396e87eff420769 557 PANTHER PTHR23077:SF75 166 200 1.5E-170 T 09-11-2016 CLOSPO_RS16020 851205cd41406c4a48a591654683c502 196 PANTHER PTHR33988:SF2 77 196 6.3E-45 T 09-11-2016 CLOSPO_RS16020 851205cd41406c4a48a591654683c502 196 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 83 194 1.3E-29 T 09-11-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 CLOSPO_RS16020 851205cd41406c4a48a591654683c502 196 PANTHER PTHR33988 77 196 6.3E-45 T 09-11-2016 CLOSPO_RS16020 851205cd41406c4a48a591654683c502 196 SUPERFAMILY SSF50118 80 195 1.37E-27 T 09-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CLOSPO_RS16020 851205cd41406c4a48a591654683c502 196 Gene3D G3DSA:2.30.30.110 81 196 2.8E-36 T 09-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 Gene3D G3DSA:3.40.50.1010 4 142 8.7E-14 T 09-11-2016 IPR029060 PIN domain-like CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 PANTHER PTHR30473 187 451 2.0E-195 T 09-11-2016 CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 Pfam PF13638 PIN domain 5 140 2.6E-33 T 09-11-2016 IPR002716 PIN domain CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 SMART SM00670 3 128 9.7E-8 T 09-11-2016 IPR002716 PIN domain CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 Gene3D G3DSA:3.40.50.300 233 452 6.6E-59 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 SUPERFAMILY SSF52540 233 323 6.01E-28 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 SUPERFAMILY SSF52540 125 191 6.01E-28 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 SUPERFAMILY SSF52540 351 417 6.01E-28 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 SUPERFAMILY SSF88723 3 64 7.06E-13 T 09-11-2016 IPR029060 PIN domain-like CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 SUPERFAMILY SSF88723 93 144 7.06E-13 T 09-11-2016 IPR029060 PIN domain-like CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 PANTHER PTHR30473:SF2 2 169 2.0E-195 T 09-11-2016 CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 PANTHER PTHR30473:SF2 187 451 2.0E-195 T 09-11-2016 CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 Pfam PF02562 PhoH-like protein 234 451 1.6E-50 T 09-11-2016 IPR003714 PhoH-like protein GO:0005524 CLOSPO_RS15740 cb720ce4ac9dd7e985252392b6d611ae 458 PANTHER PTHR30473 2 169 2.0E-195 T 09-11-2016 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PANTHER PTHR22855 21 288 2.1E-158 T 09-11-2016 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PANTHER PTHR22855:SF17 21 288 2.1E-158 T 09-11-2016 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 Gene3D G3DSA:3.90.226.10 29 287 7.3E-81 T 09-11-2016 IPR029045 ClpP/crotonase-like domain CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 SUPERFAMILY SSF52096 34 287 2.31E-81 T 09-11-2016 IPR029045 ClpP/crotonase-like domain CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 Pfam PF01039 Carboxyl transferase domain 69 248 7.8E-23 T 09-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 19 287 2.0E-125 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 287 40.756 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 169 187 6.6E-41 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 135 149 6.6E-41 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 206 223 6.6E-41 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 235 246 6.6E-41 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14870 3992c4ebdf9bf694c9821e3da3be03fd 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 257 266 6.6E-41 T 09-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 SUPERFAMILY SSF51338 348 385 3.24E-19 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 SUPERFAMILY SSF51338 2 56 3.24E-19 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 SUPERFAMILY SSF51556 55 349 9.64E-46 T 09-11-2016 IPR032466 Metal-dependent hydrolase CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 Gene3D G3DSA:3.20.20.140 62 383 8.0E-45 T 09-11-2016 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 PANTHER PTHR11271 1 389 8.4E-197 T 09-11-2016 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 PANTHER PTHR11271:SF39 1 389 8.4E-197 T 09-11-2016 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 Pfam PF01979 Amidohydrolase family 52 371 1.9E-16 T 09-11-2016 IPR006680 Amidohydrolase-related GO:0016787 CLOSPO_RS17465 f6977736ae9991cefca1226bfb0a67ad 389 Gene3D G3DSA:2.30.40.10 2 61 2.0E-16 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PANTHER PTHR22594:SF4 2 500 2.7E-278 T 09-11-2016 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 SUPERFAMILY SSF50249 14 149 4.93E-41 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PIRSF PIRSF039101 1 504 7.7E-201 T 09-11-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 2.0E-39 T 09-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 2.0E-39 T 09-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 2.0E-39 T 09-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 382 398 2.0E-39 T 09-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 2.0E-39 T 09-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 Gene3D G3DSA:3.30.930.10 151 496 6.4E-121 T 09-11-2016 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 Pfam PF01336 OB-fold nucleic acid binding domain 63 139 3.3E-15 T 09-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 PANTHER PTHR22594 2 500 2.7E-278 T 09-11-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 SUPERFAMILY SSF55681 156 498 2.87E-121 T 09-11-2016 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 500 44.796 T 09-11-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 500 2.0E-205 T 09-11-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 497 6.5E-83 T 09-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS15305 33e587e96272e1358c54a090c1e949f3 504 Gene3D G3DSA:2.40.50.140 16 149 3.1E-45 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14915 6c093e3f82f1677a33a5b954a5815c0f 414 Pfam PF13439 Glycosyltransferase Family 4 16 210 2.9E-11 T 09-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain CLOSPO_RS14915 6c093e3f82f1677a33a5b954a5815c0f 414 PANTHER PTHR12526 15 88 4.7E-33 T 09-11-2016 CLOSPO_RS14915 6c093e3f82f1677a33a5b954a5815c0f 414 PANTHER PTHR12526 112 338 4.7E-33 T 09-11-2016 CLOSPO_RS14915 6c093e3f82f1677a33a5b954a5815c0f 414 Gene3D G3DSA:3.40.50.2000 220 340 4.5E-18 T 09-11-2016 CLOSPO_RS14915 6c093e3f82f1677a33a5b954a5815c0f 414 SUPERFAMILY SSF53756 6 342 1.36E-50 T 09-11-2016 CLOSPO_RS14915 6c093e3f82f1677a33a5b954a5815c0f 414 Pfam PF00534 Glycosyl transferases group 1 213 343 7.0E-23 T 09-11-2016 IPR001296 Glycosyl transferase, family 1 CLOSPO_RS15965 79d92060f5a39494a140c554f1358517 279 PANTHER PTHR13754:SF13 2 279 7.4E-89 T 09-11-2016 CLOSPO_RS15965 79d92060f5a39494a140c554f1358517 279 Pfam PF00753 Metallo-beta-lactamase superfamily 25 85 1.8E-9 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15965 79d92060f5a39494a140c554f1358517 279 Gene3D G3DSA:3.60.15.10 1 263 1.4E-25 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15965 79d92060f5a39494a140c554f1358517 279 PANTHER PTHR13754 2 279 7.4E-89 T 09-11-2016 CLOSPO_RS15965 79d92060f5a39494a140c554f1358517 279 SUPERFAMILY SSF56281 144 255 2.75E-28 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15965 79d92060f5a39494a140c554f1358517 279 SUPERFAMILY SSF56281 11 106 2.75E-28 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 PANTHER PTHR30266 3 130 4.2E-47 T 09-11-2016 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 SUPERFAMILY SSF81330 14 125 1.24E-34 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 PANTHER PTHR30266:SF2 3 130 4.2E-47 T 09-11-2016 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 5 129 6.7E-44 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 83 91 3.3E-11 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 92 101 3.3E-11 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 7 21 3.3E-11 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 4 132 29.015 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS16110 6081d0bef1ce74da200d9c988e8257c8 133 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 130 1.9E-46 T 09-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 SUPERFAMILY SSF82689 190 286 7.06E-17 T 09-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 Pfam PF00924 Mechanosensitive ion channel 84 280 5.1E-38 T 09-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 SUPERFAMILY SSF50182 124 186 5.89E-15 T 09-11-2016 IPR010920 LSM domain CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 PANTHER PTHR30460 5 288 3.4E-94 T 09-11-2016 CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 Gene3D G3DSA:3.30.70.100 190 278 4.3E-11 T 09-11-2016 CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 SUPERFAMILY SSF82861 36 123 7.85E-6 T 09-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CLOSPO_RS14635 73a7cd0974231fcc76da71e47f7db9d0 289 Gene3D G3DSA:2.30.30.60 140 186 3.4E-14 T 09-11-2016 CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 SUPERFAMILY SSF51306 372 493 3.31E-27 T 09-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 Gene3D G3DSA:3.40.50.300 2 152 7.0E-16 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 Gene3D G3DSA:3.40.50.300 201 274 7.0E-16 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 448 460 2.2E-5 T 09-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 409 419 2.2E-5 T 09-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 420 431 2.2E-5 T 09-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 Pfam PF00717 Peptidase S24-like 412 477 3.8E-12 T 09-11-2016 IPR019759 Peptidase S24/S26A/S26B CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 Gene3D G3DSA:2.10.109.10 373 493 1.2E-36 T 09-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 SUPERFAMILY SSF52540 2 272 1.26E-18 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 PANTHER PTHR11070 1 272 1.9E-80 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 274 9.5E-5 T 09-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CLOSPO_RS17940 c6ab59ee42d64cf5e7b83a202cc4295e 495 PANTHER PTHR11070:SF18 1 272 1.9E-80 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 2 96 1.4E-24 T 09-11-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 Gene3D G3DSA:3.30.70.20 179 226 4.5E-14 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 Pfam PF00037 4Fe-4S binding domain 239 261 3.2E-8 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 Pfam PF00037 4Fe-4S binding domain 166 187 1.5E-8 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 Pfam PF04060 Putative Fe-S cluster 44 76 2.0E-12 T 09-11-2016 IPR007202 4Fe-4S domain GO:0051536 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 PANTHER PTHR24960 148 261 9.3E-19 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 217 228 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 SUPERFAMILY SSF54862 37 93 8.38E-15 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 SUPERFAMILY SSF54862 142 192 8.38E-15 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 Gene3D G3DSA:3.30.70.20 138 178 1.3E-12 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 SUPERFAMILY SSF54862 164 260 1.05E-15 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 246 257 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 Gene3D G3DSA:3.30.70.20 227 261 2.9E-13 T 09-11-2016 CLOSPO_RS12800 d6b383c7771a0e195bce6d0bf3ba80a9 277 PANTHER PTHR24960:SF20 148 261 9.3E-19 T 09-11-2016 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.9E-53 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-53 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-53 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.9E-53 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-53 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.9E-53 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PANTHER PTHR24322:SF328 11 30 1.6E-64 T 09-11-2016 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PANTHER PTHR24322:SF328 156 188 1.6E-64 T 09-11-2016 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 09-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PANTHER PTHR24322:SF328 48 140 1.6E-64 T 09-11-2016 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 5.7E-6 T 09-11-2016 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 Gene3D G3DSA:3.40.50.720 2 248 4.6E-101 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 SUPERFAMILY SSF51735 5 247 4.16E-95 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 2.4E-76 T 09-11-2016 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 246 1.1E-106 T 09-11-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 7.3E-17 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.3E-17 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.3E-17 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PANTHER PTHR24322 48 140 1.6E-64 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PANTHER PTHR24322 11 30 1.6E-64 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS14845 a132b5953940d231f8d4c916106d12a9 248 PANTHER PTHR24322 156 188 1.6E-64 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS12890 c089658d55efa951dd5f4e6b9aa28aa0 188 Gene3D G3DSA:3.40.50.150 21 168 4.0E-21 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS12890 c089658d55efa951dd5f4e6b9aa28aa0 188 SUPERFAMILY SSF53335 24 150 6.0E-23 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS12890 c089658d55efa951dd5f4e6b9aa28aa0 188 Pfam PF06962 Putative rRNA methylase 51 186 7.2E-53 T 09-11-2016 IPR010719 Putative rRNA methylase KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- CLOSPO_RS12890 c089658d55efa951dd5f4e6b9aa28aa0 188 PANTHER PTHR35276:SF1 7 188 2.5E-60 T 09-11-2016 CLOSPO_RS12890 c089658d55efa951dd5f4e6b9aa28aa0 188 PANTHER PTHR35276 7 188 2.5E-60 T 09-11-2016 CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 SUPERFAMILY SSF52540 49 208 4.48E-26 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 PANTHER PTHR32039 1 208 2.0E-99 T 09-11-2016 CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 Gene3D G3DSA:3.40.50.300 49 208 4.5E-42 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 Pfam PF01078 Magnesium chelatase, subunit ChlI 51 208 1.5E-67 T 09-11-2016 IPR000523 Magnesium chelatase ChlI domain CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 70 85 6.7E-5 T 09-11-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 151 165 6.7E-5 T 09-11-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 179 192 6.7E-5 T 09-11-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 151 166 - T 09-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOSPO_RS12430 09bdf1b5e8a4206ac80eeef635eb1122 208 PANTHER PTHR32039:SF7 1 208 2.0E-99 T 09-11-2016 IPR004482 Mg chelatase-related protein CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 SUPERFAMILY SSF46785 9 139 1.54E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 5.1E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 5.1E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 5.1E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 5.1E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 SMART SM00347 24 124 6.4E-15 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 Gene3D G3DSA:1.10.10.10 2 138 2.0E-30 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 PANTHER PTHR18964 15 140 1.2E-25 T 09-11-2016 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 PANTHER PTHR18964:SF122 15 140 1.2E-25 T 09-11-2016 CLOSPO_RS16590 a0f5c5ec18de6fb400445025cb3ea6e3 145 Pfam PF01047 MarR family 41 88 7.9E-6 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PANTHER PTHR12737:SF13 304 403 6.2E-123 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 Pfam PF02274 Amidinotransferase 21 399 4.7E-89 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 Hamap MF_00242 Arginine deiminase [arcA]. 4 402 44.866 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 TIGRFAM TIGR01078 arcA: arginine deiminase 7 401 4.6E-160 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 SUPERFAMILY SSF55909 5 402 8.44E-128 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PANTHER PTHR12737:SF13 5 94 6.2E-123 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PANTHER PTHR12737 304 403 6.2E-123 T 09-11-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PANTHER PTHR12737 147 286 6.2E-123 T 09-11-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PIRSF PIRSF006356 1 402 1.4E-162 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PANTHER PTHR12737 5 94 6.2E-123 T 09-11-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 Gene3D G3DSA:1.10.3930.10 71 147 3.3E-23 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 Gene3D G3DSA:3.75.10.10 148 400 1.4E-128 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 Gene3D G3DSA:3.75.10.10 7 69 1.4E-128 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PANTHER PTHR12737:SF13 147 286 6.2E-123 T 09-11-2016 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PRINTS PR01466 Bacterial arginine deiminase signature 381 399 1.9E-58 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PRINTS PR01466 Bacterial arginine deiminase signature 338 355 1.9E-58 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 1.9E-58 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PRINTS PR01466 Bacterial arginine deiminase signature 175 190 1.9E-58 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PRINTS PR01466 Bacterial arginine deiminase signature 358 372 1.9E-58 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14400 9ef3ac2cf0d6361f65a05d0e2d52bf7c 403 PRINTS PR01466 Bacterial arginine deiminase signature 147 165 1.9E-58 T 09-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 CLOSPO_RS14480 5e21ddb1ce553caf5079d181dd6746f0 313 SUPERFAMILY SSF143865 1 247 5.62E-51 T 09-11-2016 CLOSPO_RS14480 5e21ddb1ce553caf5079d181dd6746f0 313 Pfam PF01544 CorA-like Mg2+ transporter protein 24 309 4.4E-52 T 09-11-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CLOSPO_RS14480 5e21ddb1ce553caf5079d181dd6746f0 313 SUPERFAMILY SSF144083 248 310 1.22E-15 T 09-11-2016 CLOSPO_RS14480 5e21ddb1ce553caf5079d181dd6746f0 313 Gene3D G3DSA:1.20.58.340 237 312 7.0E-21 T 09-11-2016 CLOSPO_RS14480 5e21ddb1ce553caf5079d181dd6746f0 313 PANTHER PTHR21535:SF40 14 313 1.7E-107 T 09-11-2016 CLOSPO_RS14480 5e21ddb1ce553caf5079d181dd6746f0 313 PANTHER PTHR21535 14 313 1.7E-107 T 09-11-2016 CLOSPO_RS07380 d9fe2bda3de9a3cb3658acf4d9653220 75 Gene3D G3DSA:2.60.40.200 1 74 6.7E-22 T 09-11-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS07380 d9fe2bda3de9a3cb3658acf4d9653220 75 SUPERFAMILY SSF49329 2 75 1.83E-21 T 09-11-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS07380 d9fe2bda3de9a3cb3658acf4d9653220 75 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 2 74 2.2E-17 T 09-11-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 PANTHER PTHR30032 9 353 1.1E-37 T 09-11-2016 CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 PANTHER PTHR30032:SF1 9 353 1.1E-37 T 09-11-2016 CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 Pfam PF01841 Transglutaminase-like superfamily 756 858 2.2E-10 T 09-11-2016 IPR002931 Transglutaminase-like CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 SMART SM00460 800 861 1.3E-9 T 09-11-2016 IPR002931 Transglutaminase-like CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 SUPERFAMILY SSF54001 748 873 8.83E-20 T 09-11-2016 CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 Pfam PF04122 Putative cell wall binding repeat 2 234 325 1.5E-16 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 Pfam PF04122 Putative cell wall binding repeat 2 36 122 5.1E-20 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12750 133c226bd48d848dba7edebeb660fd3b 927 Pfam PF04122 Putative cell wall binding repeat 2 135 222 1.1E-13 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS13850 03a061aec7335b852b0f5bd07c895feb 175 PANTHER PTHR33231 1 175 1.6E-66 T 09-11-2016 CLOSPO_RS13850 03a061aec7335b852b0f5bd07c895feb 175 Gene3D G3DSA:3.30.160.100 1 94 4.7E-34 T 09-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CLOSPO_RS13850 03a061aec7335b852b0f5bd07c895feb 175 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 115 170 6.7E-31 T 09-11-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CLOSPO_RS13850 03a061aec7335b852b0f5bd07c895feb 175 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.0E-29 T 09-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CLOSPO_RS13850 03a061aec7335b852b0f5bd07c895feb 175 SUPERFAMILY SSF69754 2 108 1.44E-32 T 09-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CLOSPO_RS13850 03a061aec7335b852b0f5bd07c895feb 175 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.9E-28 T 09-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 Pfam PF12705 PD-(D/E)XK nuclease superfamily 775 1116 8.6E-57 T 09-11-2016 CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1144 0.0 T 09-11-2016 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 Gene3D G3DSA:3.40.50.300 175 231 9.0E-5 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 Gene3D G3DSA:3.40.50.300 5 87 9.0E-5 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 SUPERFAMILY SSF52540 289 735 2.87E-62 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 328 682 3.4E-16 T 09-11-2016 CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 PANTHER PTHR41262:SF1 2 1146 0.0 T 09-11-2016 CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1147 68.737 T 09-11-2016 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 Gene3D G3DSA:3.40.50.300 299 372 1.0E-6 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15475 3d4b12fcecd7e62743b21e4cb1a46e52 1147 PANTHER PTHR41262 2 1146 0.0 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 279 290 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 SUPERFAMILY SSF46548 341 443 3.14E-19 T 09-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 340 419 4.4E-22 T 09-11-2016 IPR028261 Dihydroprymidine dehydrogenase domain II CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Gene3D G3DSA:1.10.1060.10 352 434 3.6E-29 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 PANTHER PTHR11938 271 298 4.2E-46 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 PANTHER PTHR11938 386 484 4.2E-46 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Pfam PF13450 NAD(P)-binding Rossmann-like domain 437 471 5.9E-10 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Pfam PF00037 4Fe-4S binding domain 273 295 1.5E-8 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 PRINTS PR00419 Adrenodoxin reductase family signature 457 470 5.5E-10 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 PRINTS PR00419 Adrenodoxin reductase family signature 434 456 5.5E-10 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 SUPERFAMILY SSF54862 239 299 1.09E-6 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 PANTHER PTHR11938:SF70 271 298 4.2E-46 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 PANTHER PTHR11938:SF70 386 484 4.2E-46 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Gene3D G3DSA:3.50.50.60 435 483 9.4E-20 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Gene3D G3DSA:1.10.1060.10 284 351 3.8E-7 T 09-11-2016 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 SUPERFAMILY SSF51905 432 481 1.68E-14 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS05040 2203d008752317cdc5954c5e555b77af 484 Gene3D G3DSA:3.30.70.20 241 283 1.8E-4 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PANTHER PTHR24093:SF210 6 709 0.0 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 09-11-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Gene3D G3DSA:3.40.1110.10 437 527 2.9E-11 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 259 273 5.6E-22 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 559 5.6E-22 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 605 624 5.6E-22 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 641 5.6E-22 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 411 425 5.6E-22 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Pfam PF00403 Heavy-metal-associated domain 13 70 1.2E-9 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 160 708 2.9E-175 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Pfam PF00122 E1-E2 ATPase 181 402 2.1E-61 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00941 Cadmium-transporting ATPase signature 194 214 1.5E-14 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00941 Cadmium-transporting ATPase signature 20 41 1.5E-14 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00941 Cadmium-transporting ATPase signature 294 308 1.5E-14 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PRINTS PR00941 Cadmium-transporting ATPase signature 275 291 1.5E-14 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 160 710 4.5E-161 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 PANTHER PTHR24093 6 709 0.0 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Gene3D G3DSA:3.40.50.1000 528 676 4.9E-48 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 SUPERFAMILY SSF81653 212 309 3.4E-24 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Gene3D G3DSA:3.30.70.100 6 76 8.8E-13 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Gene3D G3DSA:3.40.1110.10 402 436 1.7E-4 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 SUPERFAMILY SSF81665 310 405 3.4E-12 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 SUPERFAMILY SSF81665 151 213 3.4E-12 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 SUPERFAMILY SSF56784 409 429 2.38E-57 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 SUPERFAMILY SSF56784 467 706 2.38E-57 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 SUPERFAMILY SSF55008 6 74 1.14E-11 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Pfam PF00702 haloacid dehalogenase-like hydrolase 407 619 3.8E-36 T 09-11-2016 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Gene3D G3DSA:2.70.150.10 204 310 2.5E-26 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 Gene3D G3DSA:2.70.150.10 100 114 2.5E-26 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 184 685 1.2E-76 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS17220 2e3a732946930531c212d6bd999eb4b2 714 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 413 419 - T 09-11-2016 IPR018303 P-type ATPase, phosphorylation site CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 ProSitePatterns PS00618 RecF protein signature 2. 305 323 - T 09-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 360 6.8E-106 T 09-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 SUPERFAMILY SSF52540 1 363 6.24E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 PANTHER PTHR32182:SF0 1 364 9.5E-68 T 09-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 09-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 364 91.305 T 09-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 PANTHER PTHR32182 1 364 9.5E-68 T 09-11-2016 CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 337 2.3E-14 T 09-11-2016 IPR003395 RecF/RecN/SMC, N-terminal CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 Gene3D G3DSA:3.40.50.300 230 356 3.2E-32 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14530 5ea53ccd795493815fb9d918a584da82 364 Gene3D G3DSA:3.40.50.300 1 171 3.2E-32 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 PANTHER PTHR32089 76 125 4.3E-30 T 09-11-2016 CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 2 117 3.9E-9 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 PANTHER PTHR32089:SF36 1 54 4.3E-30 T 09-11-2016 CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 PANTHER PTHR32089:SF36 76 125 4.3E-30 T 09-11-2016 CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 Gene3D G3DSA:1.10.287.950 1 94 5.3E-6 T 09-11-2016 CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 SUPERFAMILY SSF58104 1 122 1.96E-14 T 09-11-2016 CLOSPO_RS04615 3f901752b42370a5ecb65f9e305f435e 125 PANTHER PTHR32089 1 54 4.3E-30 T 09-11-2016 CLOSPO_RS17785 d19f10b613dbd41096196412d3703dd4 363 Gene3D G3DSA:3.20.20.70 63 348 1.3E-38 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS17785 d19f10b613dbd41096196412d3703dd4 363 PANTHER PTHR11228:SF19 10 339 9.5E-57 T 09-11-2016 CLOSPO_RS17785 d19f10b613dbd41096196412d3703dd4 363 Pfam PF04055 Radical SAM superfamily 67 205 9.6E-10 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS17785 d19f10b613dbd41096196412d3703dd4 363 Pfam PF13353 4Fe-4S single cluster domain 69 156 3.9E-9 T 09-11-2016 CLOSPO_RS17785 d19f10b613dbd41096196412d3703dd4 363 SUPERFAMILY SSF102114 62 350 3.14E-45 T 09-11-2016 CLOSPO_RS17785 d19f10b613dbd41096196412d3703dd4 363 PANTHER PTHR11228 10 339 9.5E-57 T 09-11-2016 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 PANTHER PTHR30185:SF2 1 136 2.4E-65 T 09-11-2016 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 Pfam PF00874 PRD domain 55 136 9.5E-21 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 SUPERFAMILY SSF63520 36 136 1.57E-26 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 Pfam PF03123 CAT RNA binding domain 1 35 7.7E-10 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 Gene3D G3DSA:2.30.24.10 1 32 4.7E-10 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 SUPERFAMILY SSF50151 1 31 1.83E-7 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 SMART SM01061 1 38 3.1E-5 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 PANTHER PTHR30185 1 136 2.4E-65 T 09-11-2016 CLOSPO_RS04440 d353bf1af19aab79956da2d53f78b59e 136 Gene3D G3DSA:1.10.1790.10 44 136 3.9E-27 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 Gene3D G3DSA:3.40.50.300 2 221 2.0E-70 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 SMART SM00382 32 218 5.9E-15 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 PANTHER PTHR24220:SF86 5 226 6.4E-106 T 09-11-2016 CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 Pfam PF00005 ABC transporter 23 169 1.5E-35 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 SUPERFAMILY SSF52540 3 221 9.74E-72 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17325 f00d2ed22e04fe4229fdaad80630c8ea 230 PANTHER PTHR24220 5 226 6.4E-106 T 09-11-2016 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 SUPERFAMILY SSF46785 8 68 5.17E-18 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 3.5E-18 T 09-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 6.2E-14 T 09-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.4E-9 T 09-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.4E-9 T 09-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.4E-9 T 09-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 PANTHER PTHR30154:SF2 1 154 2.3E-57 T 09-11-2016 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 Gene3D G3DSA:1.10.10.10 7 58 1.5E-17 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 Gene3D G3DSA:3.30.70.920 71 147 2.3E-23 T 09-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 SMART SM00344 8 115 7.2E-41 T 09-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 SUPERFAMILY SSF54909 69 150 7.24E-20 T 09-11-2016 IPR011008 Dimeric alpha-beta barrel CLOSPO_RS15975 3546209432fc9f742eea7491648abc6f 154 PANTHER PTHR30154 1 154 2.3E-57 T 09-11-2016 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 SMART SM00862 152 228 6.8E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 SUPERFAMILY SSF52172 4 186 6.34E-40 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 PANTHER PTHR26402:SF50 3 230 4.3E-96 T 09-11-2016 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 Gene3D G3DSA:1.10.10.10 129 229 9.4E-35 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 Gene3D G3DSA:3.40.50.2300 3 126 4.3E-40 T 09-11-2016 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 Pfam PF00072 Response regulator receiver domain 5 113 4.3E-28 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 SMART SM00448 3 113 6.1E-41 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 PANTHER PTHR26402 3 230 4.3E-96 T 09-11-2016 CLOSPO_RS16415 fef83bd81756ef3a0f7d87b4f7411db6 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 1.6E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 SUPERFAMILY SSF100950 89 337 8.72E-68 T 09-11-2016 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 Gene3D G3DSA:3.40.50.1360 96 339 4.7E-85 T 09-11-2016 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 PANTHER PTHR34294 87 343 7.2E-153 T 09-11-2016 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 PANTHER PTHR34294 2 67 7.2E-153 T 09-11-2016 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 Gene3D G3DSA:1.10.10.10 1 95 1.6E-33 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 PANTHER PTHR34294:SF5 2 67 7.2E-153 T 09-11-2016 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 Pfam PF04198 Putative sugar-binding domain 90 338 5.5E-67 T 09-11-2016 IPR007324 Sugar-binding domain, putative GO:0030246 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 PANTHER PTHR34294:SF5 87 343 7.2E-153 T 09-11-2016 CLOSPO_RS13580 e4508f04d3a462ab65ca8063db823a87 343 SUPERFAMILY SSF46785 19 84 1.07E-12 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SUPERFAMILY SSF47384 226 310 1.49E-19 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SMART SM00387 355 463 4.6E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 Pfam PF00672 HAMP domain 171 238 4.9E-15 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 Gene3D G3DSA:1.10.287.130 233 294 2.1E-20 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SUPERFAMILY SSF103190 73 156 5.89E-5 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 Gene3D G3DSA:3.30.450.20 43 159 3.6E-8 T 09-11-2016 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SMART SM00304 190 242 1.0E-7 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 461 2.5E-24 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 Gene3D G3DSA:3.30.565.10 295 461 2.6E-45 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SUPERFAMILY SSF158472 191 238 1.83E-8 T 09-11-2016 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 PANTHER PTHR24423 69 121 1.9E-86 T 09-11-2016 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 PANTHER PTHR24423 3 10 1.9E-86 T 09-11-2016 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 PANTHER PTHR24423 184 461 1.9E-86 T 09-11-2016 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SUPERFAMILY SSF55874 299 461 2.49E-43 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 306 1.2E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12900 ae41581ee0997d4d41431e13030c5470 464 SMART SM00388 243 309 9.1E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS15675 e782110b029f3c8856b116dd263fe403 196 PANTHER PTHR10108:SF828 4 191 1.8E-19 T 09-11-2016 CLOSPO_RS15675 e782110b029f3c8856b116dd263fe403 196 Pfam PF13847 Methyltransferase domain 35 166 1.3E-15 T 09-11-2016 IPR025714 Methyltransferase domain CLOSPO_RS15675 e782110b029f3c8856b116dd263fe403 196 SUPERFAMILY SSF53335 5 188 4.22E-32 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS15675 e782110b029f3c8856b116dd263fe403 196 PANTHER PTHR10108 4 191 1.8E-19 T 09-11-2016 CLOSPO_RS15675 e782110b029f3c8856b116dd263fe403 196 Gene3D G3DSA:3.40.50.150 5 176 1.0E-30 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14560 95fa42f9d3df49a0e82cc321c23b3e79 69 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.101 T 09-11-2016 IPR002696 Putative membrane protein insertion efficiency factor CLOSPO_RS14560 95fa42f9d3df49a0e82cc321c23b3e79 69 SMART SM01234 1 68 1.7E-41 T 09-11-2016 IPR002696 Putative membrane protein insertion efficiency factor CLOSPO_RS14560 95fa42f9d3df49a0e82cc321c23b3e79 69 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 69 6.0E-19 T 09-11-2016 IPR002696 Putative membrane protein insertion efficiency factor CLOSPO_RS14560 95fa42f9d3df49a0e82cc321c23b3e79 69 PANTHER PTHR33383 2 67 2.1E-38 T 09-11-2016 CLOSPO_RS14560 95fa42f9d3df49a0e82cc321c23b3e79 69 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 67 3.4E-29 T 09-11-2016 IPR002696 Putative membrane protein insertion efficiency factor CLOSPO_RS14560 95fa42f9d3df49a0e82cc321c23b3e79 69 Pfam PF01809 Haemolytic domain 2 67 4.9E-31 T 09-11-2016 IPR002696 Putative membrane protein insertion efficiency factor CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 SUPERFAMILY SSF52172 4 179 1.1E-39 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 PANTHER PTHR26402:SF483 5 228 5.9E-88 T 09-11-2016 CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 SMART SM00448 5 115 1.3E-35 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 Gene3D G3DSA:3.40.50.2300 2 127 4.2E-38 T 09-11-2016 CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 Pfam PF00072 Response regulator receiver domain 7 115 7.2E-29 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 Gene3D G3DSA:1.10.10.10 131 229 4.8E-33 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 5.7E-25 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 SMART SM00862 152 228 2.7E-22 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17285 2d2ff935b3560a1572d55cd2575c911d 230 PANTHER PTHR26402 5 228 5.9E-88 T 09-11-2016 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 Pfam PF07700 Haem-NO-binding 2 158 1.3E-42 T 09-11-2016 IPR011644 Heme-NO binding GO:0020037 KEGG: 00230+4.6.1.2 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 SUPERFAMILY SSF111126 1 182 7.32E-45 T 09-11-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 PANTHER PTHR32089 10 587 2.0E-110 T 09-11-2016 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 SMART SM00283 322 583 3.5E-35 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 PANTHER PTHR32089:SF1 10 587 2.0E-110 T 09-11-2016 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 201 226 7.1E-20 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 449 478 7.1E-20 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 420 447 7.1E-20 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 Gene3D G3DSA:1.10.287.950 337 570 2.3E-41 T 09-11-2016 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 Gene3D G3DSA:3.90.1520.10 1 181 4.4E-56 T 09-11-2016 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 SUPERFAMILY SSF58104 299 596 1.7E-57 T 09-11-2016 CLOSPO_RS15070 2ba1534a88d8bde9039e9189114f6c2f 598 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 400 582 1.0E-36 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 Gene3D G3DSA:2.60.120.10 224 310 1.3E-17 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 PANTHER PTHR18964 12 62 5.6E-48 T 09-11-2016 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 PANTHER PTHR18964 78 259 5.6E-48 T 09-11-2016 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 Gene3D G3DSA:2.60.120.10 1 210 1.9E-60 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 PIRSF PIRSF036894 1 310 6.3E-90 T 09-11-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 Pfam PF01238 Phosphomannose isomerase type I 5 102 2.0E-12 T 09-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 PANTHER PTHR18964:SF114 12 62 5.6E-48 T 09-11-2016 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 PANTHER PTHR18964:SF114 78 259 5.6E-48 T 09-11-2016 CLOSPO_RS12590 20c7f2b8e2f48cfa9cb6830c998b2d57 326 SUPERFAMILY SSF51182 1 311 8.43E-75 T 09-11-2016 IPR011051 RmlC-like cupin domain CLOSPO_RS16115 0cb671835149b6672f3f683c8cee018f 227 PANTHER PTHR41316 49 227 2.7E-71 T 09-11-2016 CLOSPO_RS16115 0cb671835149b6672f3f683c8cee018f 227 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 57 210 6.7E-47 T 09-11-2016 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CLOSPO_RS16115 0cb671835149b6672f3f683c8cee018f 227 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 55 211 6.0E-45 T 09-11-2016 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CLOSPO_RS16585 338f71c375cb43775e31fd2aaa1dbe22 162 Pfam PF02915 Rubrerythrin 9 146 1.6E-17 T 09-11-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS16585 338f71c375cb43775e31fd2aaa1dbe22 162 Gene3D G3DSA:1.20.1260.10 5 150 2.1E-33 T 09-11-2016 IPR012347 Ferritin-related CLOSPO_RS16585 338f71c375cb43775e31fd2aaa1dbe22 162 PANTHER PTHR33531:SF3 9 162 9.8E-39 T 09-11-2016 CLOSPO_RS16585 338f71c375cb43775e31fd2aaa1dbe22 162 PANTHER PTHR33531 9 162 9.8E-39 T 09-11-2016 CLOSPO_RS16585 338f71c375cb43775e31fd2aaa1dbe22 162 SUPERFAMILY SSF47240 6 153 4.94E-26 T 09-11-2016 IPR009078 Ferritin-like superfamily CLOSPO_RS18420 79d0a6237b65edfeab8c04e82d5bb620 127 SUPERFAMILY SSF52172 5 125 1.57E-24 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS18420 79d0a6237b65edfeab8c04e82d5bb620 127 PANTHER PTHR26402:SF579 6 127 6.8E-44 T 09-11-2016 CLOSPO_RS18420 79d0a6237b65edfeab8c04e82d5bb620 127 Pfam PF00072 Response regulator receiver domain 8 121 2.1E-21 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18420 79d0a6237b65edfeab8c04e82d5bb620 127 Gene3D G3DSA:3.40.50.2300 6 124 7.1E-27 T 09-11-2016 CLOSPO_RS18420 79d0a6237b65edfeab8c04e82d5bb620 127 PANTHER PTHR26402 6 127 6.8E-44 T 09-11-2016 CLOSPO_RS18420 79d0a6237b65edfeab8c04e82d5bb620 127 SMART SM00448 6 121 2.4E-20 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS14810 eba0ee2aaa515c3a828886a91fa7912a 311 PANTHER PTHR21666 93 310 2.3E-49 T 09-11-2016 CLOSPO_RS14810 eba0ee2aaa515c3a828886a91fa7912a 311 Pfam PF01551 Peptidase family M23 212 306 1.9E-36 T 09-11-2016 IPR016047 Peptidase M23 CLOSPO_RS14810 eba0ee2aaa515c3a828886a91fa7912a 311 SUPERFAMILY SSF51261 129 310 4.32E-56 T 09-11-2016 IPR011055 Duplicated hybrid motif CLOSPO_RS14810 eba0ee2aaa515c3a828886a91fa7912a 311 Gene3D G3DSA:2.70.70.10 178 311 3.3E-50 T 09-11-2016 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 Gene3D G3DSA:3.40.50.2300 10 122 1.3E-15 T 09-11-2016 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 Gene3D G3DSA:2.40.50.40 125 193 3.8E-25 T 09-11-2016 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 SUPERFAMILY SSF52172 12 140 1.57E-15 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 Pfam PF04397 LytTr DNA-binding domain 134 223 6.4E-24 T 09-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 SMART SM00448 1 113 9.9E-7 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 PANTHER PTHR26402:SF472 1 142 6.1E-25 T 09-11-2016 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 Pfam PF00072 Response regulator receiver domain 19 108 5.3E-14 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 PANTHER PTHR26402 1 142 6.1E-25 T 09-11-2016 CLOSPO_RS16215 acc30ee4664f1830288c0ccf0fc85eca 233 SMART SM00850 133 224 9.0E-29 T 09-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 Gene3D G3DSA:3.60.15.10 1 242 1.2E-79 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 SUPERFAMILY SSF56281 10 283 5.5E-44 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 Gene3D G3DSA:3.40.50.360 247 398 7.8E-43 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 Pfam PF00258 Flavodoxin 253 364 4.9E-9 T 09-11-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 SMART SM00849 34 223 7.2E-23 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 PANTHER PTHR32145:SF2 2 404 4.0E-157 T 09-11-2016 CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 PIRSF PIRSF005243 1 408 1.7E-131 T 09-11-2016 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 PANTHER PTHR32145 2 404 4.0E-157 T 09-11-2016 CLOSPO_RS16745 2d7f1ba33558ba33e28bd4ff1a0ebe1c 410 SUPERFAMILY SSF52218 248 397 6.54E-30 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS14450 b19a278672cf8a344020581297f15f7d 109 SUPERFAMILY SSF54913 1 109 4.45E-14 T 09-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta CLOSPO_RS14450 b19a278672cf8a344020581297f15f7d 109 PANTHER PTHR38456 2 109 8.7E-45 T 09-11-2016 CLOSPO_RS14450 b19a278672cf8a344020581297f15f7d 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 5.9E-51 T 09-11-2016 IPR010375 Cyclic-di-AMP receptor CLOSPO_RS14450 b19a278672cf8a344020581297f15f7d 109 Gene3D G3DSA:3.30.70.120 1 109 4.4E-18 T 09-11-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 436 443 - T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 455 1.4E-133 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 Pfam PF04552 Sigma-54, DNA binding domain 296 456 4.3E-57 T 09-11-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PIRSF PIRSF000774 1 457 2.5E-141 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PANTHER PTHR32248:SF4 2 457 1.3E-149 T 09-11-2016 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 SUPERFAMILY SSF46785 321 381 7.08E-5 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 343 362 - T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 Gene3D G3DSA:1.10.10.10 322 380 2.4E-4 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PANTHER PTHR32248 2 457 1.3E-149 T 09-11-2016 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 50 1.6E-17 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PRINTS PR00045 Sigma-54 factor signature 167 184 5.0E-22 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PRINTS PR00045 Sigma-54 factor signature 431 449 5.0E-22 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PRINTS PR00045 Sigma-54 factor signature 355 367 5.0E-22 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 PRINTS PR00045 Sigma-54 factor signature 371 382 5.0E-22 T 09-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS13585 1f4470e3e4e4169ee0662699e6c4aaa5 457 Pfam PF04963 Sigma-54 factor, core binding domain 96 282 2.3E-49 T 09-11-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CLOSPO_RS04120 a55ca67ab213fe8c9e4f79997ffa644a 134 SUPERFAMILY SSF52540 1 134 1.98E-32 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04120 a55ca67ab213fe8c9e4f79997ffa644a 134 PANTHER PTHR24220 1 134 1.2E-49 T 09-11-2016 CLOSPO_RS04120 a55ca67ab213fe8c9e4f79997ffa644a 134 PANTHER PTHR24220:SF331 1 134 1.2E-49 T 09-11-2016 CLOSPO_RS04120 a55ca67ab213fe8c9e4f79997ffa644a 134 Gene3D G3DSA:3.40.50.300 2 134 1.2E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04120 a55ca67ab213fe8c9e4f79997ffa644a 134 Pfam PF00005 ABC transporter 13 134 2.2E-20 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 SUPERFAMILY SSF56784 3 229 5.83E-29 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 PANTHER PTHR10000 1 234 1.9E-131 T 09-11-2016 CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 Gene3D G3DSA:3.40.50.1000 79 212 8.7E-34 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 PANTHER PTHR10000:SF11 1 234 1.9E-131 T 09-11-2016 CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 205 5.8E-61 T 09-11-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 192 7.3E-20 T 09-11-2016 CLOSPO_RS18920 09a3d526ffb2510d19fa3e982f22c0c8 241 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 194 1.3E-37 T 09-11-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 SMART SM00422 3 71 1.0E-23 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 Pfam PF07739 TipAS antibiotic-recognition domain 292 385 9.8E-10 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 Pfam PF07739 TipAS antibiotic-recognition domain 160 290 9.1E-16 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 PANTHER PTHR30204 3 203 2.5E-31 T 09-11-2016 CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 SUPERFAMILY SSF46955 3 104 1.83E-25 T 09-11-2016 IPR009061 Putative DNA-binding domain CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 Pfam PF13411 MerR HTH family regulatory protein 3 70 5.6E-15 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 PANTHER PTHR30204:SF27 3 203 2.5E-31 T 09-11-2016 CLOSPO_RS17795 6e21d9382a73a3af2bd66697ca1c59e5 390 Gene3D G3DSA:1.10.1660.10 3 109 4.1E-25 T 09-11-2016 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 39.434 T 09-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 SUPERFAMILY SSF51161 256 445 8.62E-46 T 09-11-2016 IPR011004 Trimeric LpxA-like CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Gene3D G3DSA:3.90.550.10 3 244 1.2E-73 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 PANTHER PTHR22572 5 448 1.8E-221 T 09-11-2016 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 452 2.9E-171 T 09-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Pfam PF00483 Nucleotidyl transferase 5 214 7.3E-24 T 09-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 SUPERFAMILY SSF53448 2 253 3.15E-63 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 299 3.7E-5 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 2.3E-6 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 428 3.4E-8 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 PANTHER PTHR22572:SF115 5 448 1.8E-221 T 09-11-2016 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Gene3D G3DSA:2.160.10.10 324 451 1.2E-35 T 09-11-2016 CLOSPO_RS15140 59c388b887921df6d6e492aa3cde1cbc 457 Gene3D G3DSA:2.160.10.10 245 323 1.1E-17 T 09-11-2016 CLOSPO_RS13355 b19abd35f787f6c69bdcef58c8fd4edf 300 Pfam PF13527 Acetyltransferase (GNAT) domain 39 139 2.2E-12 T 09-11-2016 CLOSPO_RS13355 b19abd35f787f6c69bdcef58c8fd4edf 300 Gene3D G3DSA:3.40.630.30 26 90 4.9E-7 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13355 b19abd35f787f6c69bdcef58c8fd4edf 300 Gene3D G3DSA:3.40.630.30 91 145 1.0E-13 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13355 b19abd35f787f6c69bdcef58c8fd4edf 300 PANTHER PTHR23091:SF218 21 188 3.5E-57 T 09-11-2016 CLOSPO_RS13355 b19abd35f787f6c69bdcef58c8fd4edf 300 SUPERFAMILY SSF55729 26 257 6.62E-34 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13355 b19abd35f787f6c69bdcef58c8fd4edf 300 PANTHER PTHR23091 21 188 3.5E-57 T 09-11-2016 CLOSPO_RS17125 9c39f0f31c06fd7f967f3c628775f996 383 PANTHER PTHR11039:SF44 6 378 2.1E-12 T 09-11-2016 CLOSPO_RS17125 9c39f0f31c06fd7f967f3c628775f996 383 PANTHER PTHR11039 6 378 2.1E-12 T 09-11-2016 CLOSPO_RS17125 9c39f0f31c06fd7f967f3c628775f996 383 SMART SM00460 188 248 1.3E-5 T 09-11-2016 IPR002931 Transglutaminase-like CLOSPO_RS17125 9c39f0f31c06fd7f967f3c628775f996 383 SUPERFAMILY SSF54001 90 255 1.79E-19 T 09-11-2016 CLOSPO_RS17125 9c39f0f31c06fd7f967f3c628775f996 383 Pfam PF01841 Transglutaminase-like superfamily 144 245 6.4E-9 T 09-11-2016 IPR002931 Transglutaminase-like CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 PANTHER PTHR30055:SF52 1 198 3.2E-117 T 09-11-2016 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 Gene3D G3DSA:1.10.357.10 5 202 1.5E-39 T 09-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.5E-7 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.5E-7 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 PANTHER PTHR30055 1 198 3.2E-117 T 09-11-2016 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 2.2E-12 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 SUPERFAMILY SSF46689 6 78 9.93E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 SUPERFAMILY SSF48498 85 203 5.48E-13 T 09-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CLOSPO_RS18550 cd16ccd24361e1e14f7857a2f7a2d9cd 204 Pfam PF13305 WHG domain 94 180 2.3E-10 T 09-11-2016 IPR025996 WHG domain CLOSPO_RS13105 41a7913e7a196eea5792fa1d0a85c6e6 440 PIRSF PIRSF006603 1 440 2.3E-93 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS13105 41a7913e7a196eea5792fa1d0a85c6e6 440 Pfam PF01554 MatE 20 180 9.6E-34 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS13105 41a7913e7a196eea5792fa1d0a85c6e6 440 Pfam PF01554 MatE 244 403 2.0E-24 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS13105 41a7913e7a196eea5792fa1d0a85c6e6 440 PANTHER PTHR11206 2 436 1.4E-188 T 09-11-2016 CLOSPO_RS13105 41a7913e7a196eea5792fa1d0a85c6e6 440 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 415 1.8E-64 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS13105 41a7913e7a196eea5792fa1d0a85c6e6 440 PANTHER PTHR11206:SF107 2 436 1.4E-188 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 Pfam PF12838 4Fe-4S dicluster domain 171 218 1.0E-8 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 98 300 3.0E-28 T 09-11-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 204 215 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 PANTHER PTHR11493 3 162 3.2E-160 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 PANTHER PTHR11493:SF49 220 320 3.2E-160 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 143 159 - T 09-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 SUPERFAMILY SSF56014 101 165 3.55E-34 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 SUPERFAMILY SSF56014 225 305 3.55E-34 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 PANTHER PTHR11493:SF49 3 162 3.2E-160 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 PANTHER PTHR11493 220 320 3.2E-160 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 TIGRFAM TIGR02912 sulfite_red_C: sulfite reductase, subunit C 2 315 1.8E-184 T 09-11-2016 IPR014261 Sulphite reductase, subunit C UniPathway: UPA00370 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 SUPERFAMILY SSF54862 145 226 3.81E-18 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 PRINTS PR00397 Sirohaem Fe-binding site signature 143 161 7.4E-7 T 09-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 PRINTS PR00397 Sirohaem Fe-binding site signature 102 120 7.4E-7 T 09-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 20 79 2.7E-15 T 09-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 SUPERFAMILY SSF55124 5 80 8.83E-17 T 09-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 Gene3D G3DSA:3.30.70.20 152 226 2.1E-15 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 Gene3D G3DSA:3.30.413.10 227 298 3.2E-36 T 09-11-2016 CLOSPO_RS18205 05188d9d02375ff01ab34a6d1a0e10e3 321 Gene3D G3DSA:3.30.413.10 101 151 3.2E-36 T 09-11-2016 CLOSPO_RS13900 75fb26ee81a744b4f1f972be8c7a4a9c 240 PIRSF PIRSF004976 1 240 6.9E-64 T 09-11-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 CLOSPO_RS13900 75fb26ee81a744b4f1f972be8c7a4a9c 240 Gene3D G3DSA:3.40.50.620 14 187 1.3E-19 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS13900 75fb26ee81a744b4f1f972be8c7a4a9c 240 Pfam PF01171 PP-loop family 24 200 2.3E-20 T 09-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal CLOSPO_RS13900 75fb26ee81a744b4f1f972be8c7a4a9c 240 SUPERFAMILY SSF52402 2 214 8.82E-51 T 09-11-2016 CLOSPO_RS13900 75fb26ee81a744b4f1f972be8c7a4a9c 240 PANTHER PTHR11807:SF22 1 240 5.8E-155 T 09-11-2016 CLOSPO_RS13900 75fb26ee81a744b4f1f972be8c7a4a9c 240 PANTHER PTHR11807 1 240 5.8E-155 T 09-11-2016 CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 Pfam PF00583 Acetyltransferase (GNAT) family 55 134 2.8E-11 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 Gene3D G3DSA:3.40.630.30 12 150 9.7E-17 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 Gene3D G3DSA:3.40.630.30 178 277 2.2E-10 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 PANTHER PTHR23091 12 138 7.4E-15 T 09-11-2016 CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 Pfam PF13673 Acetyltransferase (GNAT) domain 194 273 6.2E-8 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 SUPERFAMILY SSF55729 39 280 5.92E-18 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18340 b05247f388497f32b7f5f6fe0b1b56db 284 PANTHER PTHR23091:SF253 12 138 7.4E-15 T 09-11-2016 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 SUPERFAMILY SSF48334 21 284 7.32E-22 T 09-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 PANTHER PTHR11361 16 597 0.0 T 09-11-2016 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 404 420 - T 09-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 SUPERFAMILY SSF52540 289 508 2.62E-33 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 SMART SM00533 9 311 8.2E-10 T 09-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 Pfam PF00488 MutS domain V 325 506 6.6E-34 T 09-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 PANTHER PTHR11361:SF90 16 597 0.0 T 09-11-2016 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 Pfam PF05192 MutS domain III 21 278 2.2E-6 T 09-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 SMART SM00534 322 507 1.2E-58 T 09-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 Gene3D G3DSA:3.40.50.300 289 507 7.9E-55 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16515 98f1441faa7e43daa376a0ce55aedd72 631 PIRSF PIRSF005814 1 630 2.4E-192 T 09-11-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOSPO_RS15200 e066e7c137b5a39b57dc4f85ef1b0305 79 Gene3D G3DSA:3.10.290.10 2 77 1.3E-20 T 09-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 CLOSPO_RS15200 e066e7c137b5a39b57dc4f85ef1b0305 79 SMART SM00363 1 61 9.6E-9 T 09-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 CLOSPO_RS15200 e066e7c137b5a39b57dc4f85ef1b0305 79 PIRSF PIRSF038881 1 79 1.2E-30 T 09-11-2016 IPR025490 RNA-binding protein, HP1423 type CLOSPO_RS15200 e066e7c137b5a39b57dc4f85ef1b0305 79 Pfam PF01479 S4 domain 1 46 1.9E-10 T 09-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 CLOSPO_RS15200 e066e7c137b5a39b57dc4f85ef1b0305 79 SUPERFAMILY SSF55174 2 76 1.05E-18 T 09-11-2016 CLOSPO_RS16045 0834fb546b9271f96f189a2a64484d36 277 PANTHER PTHR10794 141 228 1.2E-17 T 09-11-2016 CLOSPO_RS16045 0834fb546b9271f96f189a2a64484d36 277 Pfam PF02517 CAAX protease self-immunity 137 224 2.5E-21 T 09-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 CLOSPO_RS18945 2ef60fbb2e846459fb1ca58f2d73452f 270 PANTHER PTHR30429 1 270 3.4E-150 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS18945 2ef60fbb2e846459fb1ca58f2d73452f 270 SUPERFAMILY SSF53850 36 270 2.3E-86 T 09-11-2016 CLOSPO_RS18945 2ef60fbb2e846459fb1ca58f2d73452f 270 Gene3D G3DSA:3.40.190.10 33 163 1.4E-58 T 09-11-2016 CLOSPO_RS18945 2ef60fbb2e846459fb1ca58f2d73452f 270 PIRSF PIRSF002854 1 270 1.0E-108 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS18945 2ef60fbb2e846459fb1ca58f2d73452f 270 PANTHER PTHR30429:SF0 1 270 3.4E-150 T 09-11-2016 CLOSPO_RS18945 2ef60fbb2e846459fb1ca58f2d73452f 270 Pfam PF03180 NLPA lipoprotein 37 270 9.2E-97 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 Pfam PF13624 SurA N-terminal domain 2 164 1.7E-21 T 09-11-2016 CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 223 244 - T 09-11-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 SUPERFAMILY SSF109998 36 224 2.75E-33 T 09-11-2016 IPR027304 Trigger factor/SurA domain CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 Gene3D G3DSA:3.10.50.40 192 311 4.0E-35 T 09-11-2016 CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 PANTHER PTHR10657 36 335 2.3E-69 T 09-11-2016 CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 SUPERFAMILY SSF54534 195 285 4.97E-25 T 09-11-2016 CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 Pfam PF13616 PPIC-type PPIASE domain 181 288 6.1E-20 T 09-11-2016 CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 Hamap MF_01145 Foldase protein PrsA [prsA]. 5 336 16.005 T 09-11-2016 IPR023059 Foldase protein PrsA GO:0003755 CLOSPO_RS15175 22a801174f02ec2d75605f41f308c580 336 PANTHER PTHR10657:SF11 36 335 2.3E-69 T 09-11-2016 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 SMART SM00342 201 283 1.9E-21 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 SUPERFAMILY SSF51215 31 167 6.67E-13 T 09-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 PANTHER PTHR11019:SF11 18 288 1.3E-61 T 09-11-2016 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 Gene3D G3DSA:1.10.10.60 245 287 5.1E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 Gene3D G3DSA:2.60.120.10 18 91 2.2E-9 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 Gene3D G3DSA:1.10.10.60 182 238 1.0E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 SUPERFAMILY SSF46689 184 236 1.61E-7 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 Pfam PF02311 AraC-like ligand binding domain 26 100 4.3E-7 T 09-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 PANTHER PTHR11019 18 288 1.3E-61 T 09-11-2016 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 267 283 8.2E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 267 8.2E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 SUPERFAMILY SSF46689 238 287 9.41E-10 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16165 3f6951f7de67cc7c6d2c41710cb0dd01 289 Pfam PF12833 Helix-turn-helix domain 208 284 6.9E-18 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 PANTHER PTHR11911:SF104 1 128 8.7E-54 T 09-11-2016 CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 Gene3D G3DSA:3.10.580.10 1 116 6.8E-38 T 09-11-2016 CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 PANTHER PTHR11911 1 128 8.7E-54 T 09-11-2016 CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 Pfam PF00571 CBS domain 3 53 3.6E-15 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 Pfam PF00571 CBS domain 67 117 1.5E-14 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 SUPERFAMILY SSF54631 1 116 1.52E-36 T 09-11-2016 CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 SMART SM00116 74 121 4.8E-9 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS13710 17a87fde667c74ba2e39cca96e96c162 138 SMART SM00116 10 57 6.4E-11 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS12580 fc1d877dde74076adcea2a12d52eb05b 284 Pfam PF02673 Bacitracin resistance protein BacA 7 271 5.8E-79 T 09-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOSPO_RS12580 fc1d877dde74076adcea2a12d52eb05b 284 PANTHER PTHR30622:SF3 1 284 3.6E-145 T 09-11-2016 CLOSPO_RS12580 fc1d877dde74076adcea2a12d52eb05b 284 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 269 1.9E-73 T 09-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOSPO_RS12580 fc1d877dde74076adcea2a12d52eb05b 284 PANTHER PTHR30622 1 284 3.6E-145 T 09-11-2016 CLOSPO_RS12580 fc1d877dde74076adcea2a12d52eb05b 284 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 276 17.816 T 09-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 SUPERFAMILY SSF54862 252 312 3.03E-6 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:1.10.1060.10 298 363 9.5E-7 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:3.30.70.20 836 854 2.3E-22 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:3.30.70.20 271 297 2.3E-22 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:1.10.1060.10 364 448 9.4E-29 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:1.10.1060.10 773 835 5.4E-7 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:3.40.50.720 449 536 1.1E-24 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:3.40.50.720 692 769 1.1E-24 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 SUPERFAMILY SSF46548 748 848 3.4E-10 T 09-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 SUPERFAMILY SSF46548 354 456 8.37E-19 T 09-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PANTHER PTHR11938 284 311 6.4E-175 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PRINTS PR00419 Adrenodoxin reductase family signature 470 483 4.5E-20 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PRINTS PR00419 Adrenodoxin reductase family signature 579 593 4.5E-20 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PRINTS PR00419 Adrenodoxin reductase family signature 447 469 4.5E-20 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PRINTS PR00419 Adrenodoxin reductase family signature 512 522 4.5E-20 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PANTHER PTHR11938:SF70 284 311 6.4E-175 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 447 741 3.3E-26 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PANTHER PTHR11938 399 754 6.4E-175 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 292 303 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 353 432 1.0E-21 T 09-11-2016 IPR028261 Dihydroprymidine dehydrogenase domain II CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 SUPERFAMILY SSF51971 445 688 1.12E-56 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 PANTHER PTHR11938:SF70 399 754 6.4E-175 T 09-11-2016 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Gene3D G3DSA:3.50.50.60 537 688 5.7E-38 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS17375 a8386fcc3043dca0de89756ef143e452 898 Pfam PF00037 4Fe-4S binding domain 286 308 3.1E-8 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 PIRSF PIRSF001123 5 344 1.1E-39 T 09-11-2016 IPR008007 Peptidase M42 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 SUPERFAMILY SSF101821 74 187 1.14E-28 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 Pfam PF05343 M42 glutamyl aminopeptidase 49 337 2.4E-81 T 09-11-2016 IPR008007 Peptidase M42 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 Gene3D G3DSA:3.40.630.10 3 73 6.3E-59 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 Gene3D G3DSA:3.40.630.10 171 343 6.3E-59 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 SUPERFAMILY SSF53187 175 343 1.54E-53 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 SUPERFAMILY SSF53187 8 79 1.54E-53 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 PANTHER PTHR32481:SF7 3 344 3.1E-198 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 PANTHER PTHR32481 3 344 3.1E-198 T 09-11-2016 CLOSPO_RS13640 de5eba76532a108716ec41939538fffb 344 Gene3D G3DSA:2.40.30.40 74 170 3.2E-30 T 09-11-2016 IPR023367 Peptidase M42, domain 2 CLOSPO_RS16270 4eeb908e5f106df51598a9d103c29b68 822 PANTHER PTHR30489:SF0 226 821 4.3E-283 T 09-11-2016 CLOSPO_RS16270 4eeb908e5f106df51598a9d103c29b68 822 Pfam PF02687 FtsX-like permease family 255 369 1.2E-16 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS16270 4eeb908e5f106df51598a9d103c29b68 822 Pfam PF02687 FtsX-like permease family 696 813 3.7E-12 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS16270 4eeb908e5f106df51598a9d103c29b68 822 PANTHER PTHR30489 1 185 4.3E-283 T 09-11-2016 CLOSPO_RS16270 4eeb908e5f106df51598a9d103c29b68 822 PANTHER PTHR30489 226 821 4.3E-283 T 09-11-2016 CLOSPO_RS16270 4eeb908e5f106df51598a9d103c29b68 822 PANTHER PTHR30489:SF0 1 185 4.3E-283 T 09-11-2016 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 Gene3D G3DSA:3.40.50.20 2 129 1.8E-50 T 09-11-2016 IPR016185 Pre-ATP-grasp domain CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 SUPERFAMILY SSF51246 331 445 2.88E-43 T 09-11-2016 IPR011054 Rudiment single hybrid motif CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 2 446 1.5E-227 T 09-11-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 3.6E-45 T 09-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 PANTHER PTHR18866 1 443 0.0 T 09-11-2016 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 SUPERFAMILY SSF56059 83 348 7.74E-74 T 09-11-2016 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 SMART SM00878 336 442 9.4E-61 T 09-11-2016 IPR005482 Biotin carboxylase, C-terminal CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 Gene3D G3DSA:3.30.1490.20 130 202 3.8E-31 T 09-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 09-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 09-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 SUPERFAMILY SSF52440 1 111 2.16E-48 T 09-11-2016 IPR016185 Pre-ATP-grasp domain CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.7E-82 T 09-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 6.8E-38 T 09-11-2016 IPR005482 Biotin carboxylase, C-terminal CLOSPO_RS14865 6094c64907e5dcb3cc2af8db1b64bc31 448 Gene3D G3DSA:3.30.470.20 203 444 3.7E-102 T 09-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 Pfam PF02687 FtsX-like permease family 306 426 4.8E-18 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 Pfam PF02687 FtsX-like permease family 774 889 2.5E-18 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 PANTHER PTHR30489 279 650 1.3E-211 T 09-11-2016 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 PANTHER PTHR30489 667 897 1.3E-211 T 09-11-2016 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 PANTHER PTHR30489:SF0 1 186 1.3E-211 T 09-11-2016 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 PANTHER PTHR30489:SF0 279 650 1.3E-211 T 09-11-2016 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 PANTHER PTHR30489:SF0 667 897 1.3E-211 T 09-11-2016 CLOSPO_RS17330 a7fe110b5dc611bf484174596c8a76ae 898 PANTHER PTHR30489 1 186 1.3E-211 T 09-11-2016 CLOSPO_RS12870 03f1cb5403f9d098ad360010d8537630 446 PANTHER PTHR11206 7 443 2.1E-85 T 09-11-2016 CLOSPO_RS12870 03f1cb5403f9d098ad360010d8537630 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 408 9.4E-67 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS12870 03f1cb5403f9d098ad360010d8537630 446 PANTHER PTHR11206:SF95 7 443 2.1E-85 T 09-11-2016 CLOSPO_RS12870 03f1cb5403f9d098ad360010d8537630 446 PIRSF PIRSF006603 1 445 3.7E-74 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS12870 03f1cb5403f9d098ad360010d8537630 446 Pfam PF01554 MatE 243 405 8.0E-28 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS12870 03f1cb5403f9d098ad360010d8537630 446 Pfam PF01554 MatE 16 179 1.9E-26 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 Gene3D G3DSA:1.10.10.60 273 320 2.8E-16 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 PANTHER PTHR11019:SF141 24 326 1.8E-51 T 09-11-2016 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 Gene3D G3DSA:1.10.10.60 217 272 1.6E-8 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 SUPERFAMILY SSF46689 271 322 9.32E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 PANTHER PTHR11019 24 326 1.8E-51 T 09-11-2016 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 Pfam PF12833 Helix-turn-helix domain 241 319 1.3E-18 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 SMART SM00342 235 318 5.7E-20 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 302 318 5.0E-5 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 287 302 5.0E-5 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 SUPERFAMILY SSF46689 219 269 2.69E-5 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16605 43dd822a217969390707d1ed16ccefcd 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 272 314 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16800 35d5dba2d1e7660abfa86e031815be1e 297 PANTHER PTHR32196 4 291 1.5E-148 T 09-11-2016 CLOSPO_RS16800 35d5dba2d1e7660abfa86e031815be1e 297 PANTHER PTHR32196:SF27 4 291 1.5E-148 T 09-11-2016 CLOSPO_RS16800 35d5dba2d1e7660abfa86e031815be1e 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 267 2.5E-26 T 09-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 195 5.3E-6 T 09-11-2016 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 116 130 5.3E-6 T 09-11-2016 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 246 5.3E-6 T 09-11-2016 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 16 281 2.7E-69 T 09-11-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 PANTHER PTHR18895 13 283 3.5E-95 T 09-11-2016 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 Gene3D G3DSA:3.40.50.150 88 282 1.6E-60 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 SUPERFAMILY SSF53335 18 280 5.49E-50 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 Gene3D G3DSA:1.10.8.10 4 85 1.0E-18 T 09-11-2016 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 Pfam PF05175 Methyltransferase small domain 104 196 1.6E-14 T 09-11-2016 IPR007848 Methyltransferase small domain GO:0008168 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 282 41.98 T 09-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 PANTHER PTHR18895:SF64 13 283 3.5E-95 T 09-11-2016 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 09-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOSPO_RS14035 468e2946ccd491ad377fcee724db4f9c 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 278 3.9E-85 T 09-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CLOSPO_RS16625 65131abf13ab18d2d7374743f8b88f82 327 Pfam PF09992 Phosphodiester glycosidase 140 325 3.4E-47 T 09-11-2016 IPR018711 Phosphodiester glycosidase CLOSPO_RS16625 65131abf13ab18d2d7374743f8b88f82 327 PANTHER PTHR40446:SF1 208 326 4.3E-33 T 09-11-2016 CLOSPO_RS16625 65131abf13ab18d2d7374743f8b88f82 327 PANTHER PTHR40446 208 326 4.3E-33 T 09-11-2016 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 09-11-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 Gene3D G3DSA:1.10.300.10 102 196 3.3E-37 T 09-11-2016 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 5.6E-174 T 09-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 SMART SM00788 3 424 1.0E-286 T 09-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 PANTHER PTHR11846 5 428 1.3E-250 T 09-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 09-11-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 SUPERFAMILY SSF52540 1 426 9.35E-176 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 206.882 T 09-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 Gene3D G3DSA:3.40.440.10 197 266 6.8E-74 T 09-11-2016 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 Gene3D G3DSA:3.40.440.10 2 93 6.8E-74 T 09-11-2016 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 Pfam PF00709 Adenylosuccinate synthetase 5 423 1.9E-184 T 09-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 CLOSPO_RS14715 3ac44317c4d6a69a2aa37153d4165010 428 Gene3D G3DSA:3.90.170.10 267 425 1.8E-67 T 09-11-2016 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 PANTHER PTHR36566:SF1 95 424 1.4E-104 T 09-11-2016 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 PANTHER PTHR36566 95 424 1.4E-104 T 09-11-2016 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 PANTHER PTHR36566:SF1 3 68 1.4E-104 T 09-11-2016 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 PANTHER PTHR36566 3 68 1.4E-104 T 09-11-2016 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 Pfam PF01969 Protein of unknown function DUF111 5 419 8.6E-154 T 09-11-2016 IPR002822 Uncharacterised protein family UPF0272 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 Gene3D G3DSA:3.30.70.1380 279 369 4.5E-31 T 09-11-2016 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 4 419 7.1E-111 T 09-11-2016 IPR002822 Uncharacterised protein family UPF0272 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 Hamap MF_01074 UPF0272 protein . 2 427 40.34 T 09-11-2016 IPR002822 Uncharacterised protein family UPF0272 CLOSPO_RS14210 f92d966bdb5634aa07b0b7399cacceb6 427 Gene3D G3DSA:3.10.20.300 370 425 1.2E-19 T 09-11-2016 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 SUPERFAMILY SSF55874 180 342 6.68E-40 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 PANTHER PTHR24423 64 342 4.2E-74 T 09-11-2016 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 PANTHER PTHR24423 1 7 4.2E-74 T 09-11-2016 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 341 4.1E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 SMART SM00304 70 123 7.6E-11 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 189 1.0E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 SMART SM00387 234 342 1.7E-30 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 SUPERFAMILY SSF158472 72 120 1.57E-9 T 09-11-2016 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 4.0E-17 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 4.0E-17 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 4.0E-17 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 4.0E-17 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 Gene3D G3DSA:1.10.287.130 116 184 6.0E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 SMART SM00388 124 190 3.6E-18 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 Pfam PF00672 HAMP domain 50 118 1.3E-11 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 SUPERFAMILY SSF47384 107 191 3.53E-18 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS17905 bc93b8b3dcc0ca9e8c5ef38332ed6745 342 Gene3D G3DSA:3.30.565.10 197 341 2.1E-40 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS02705 640f510f341ac29e58aee118010c896a 111 PANTHER PTHR14025:SF21 2 111 4.0E-42 T 09-11-2016 CLOSPO_RS02705 640f510f341ac29e58aee118010c896a 111 PANTHER PTHR14025 2 111 4.0E-42 T 09-11-2016 CLOSPO_RS02705 640f510f341ac29e58aee118010c896a 111 SMART SM00982 64 111 2.8E-4 T 09-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CLOSPO_RS02705 640f510f341ac29e58aee118010c896a 111 Pfam PF03461 TRCF domain 65 110 7.2E-16 T 09-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CLOSPO_RS02705 640f510f341ac29e58aee118010c896a 111 SUPERFAMILY SSF143517 51 109 8.89E-20 T 09-11-2016 CLOSPO_RS16990 7505a32ab7d22aae5debc9e3fd67dd23 62 Gene3D G3DSA:1.10.260.40 2 61 1.3E-22 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16990 7505a32ab7d22aae5debc9e3fd67dd23 62 Pfam PF01381 Helix-turn-helix 11 61 1.3E-15 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16990 7505a32ab7d22aae5debc9e3fd67dd23 62 PANTHER PTHR10245:SF9 2 62 5.0E-26 T 09-11-2016 CLOSPO_RS16990 7505a32ab7d22aae5debc9e3fd67dd23 62 SUPERFAMILY SSF47413 2 61 1.93E-17 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16990 7505a32ab7d22aae5debc9e3fd67dd23 62 PANTHER PTHR10245 2 62 5.0E-26 T 09-11-2016 CLOSPO_RS16990 7505a32ab7d22aae5debc9e3fd67dd23 62 SMART SM00530 10 60 3.2E-9 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS15795 d8301f95464d3c43d9ca602dad26a4d6 380 Gene3D G3DSA:3.40.1710.10 44 119 5.7E-4 T 09-11-2016 CLOSPO_RS15795 d8301f95464d3c43d9ca602dad26a4d6 380 PANTHER PTHR30294:SF21 1 375 1.3E-111 T 09-11-2016 CLOSPO_RS15795 d8301f95464d3c43d9ca602dad26a4d6 380 Pfam PF12698 ABC-2 family transporter protein 21 368 4.7E-36 T 09-11-2016 CLOSPO_RS15795 d8301f95464d3c43d9ca602dad26a4d6 380 PANTHER PTHR30294 1 375 1.3E-111 T 09-11-2016 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 SMART SM00448 5 115 1.8E-31 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 SMART SM00862 153 231 3.3E-24 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 3.7E-25 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 Pfam PF00072 Response regulator receiver domain 7 116 6.7E-25 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 Gene3D G3DSA:3.40.50.2300 3 127 1.3E-33 T 09-11-2016 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 PANTHER PTHR26402 5 233 1.1E-73 T 09-11-2016 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 Gene3D G3DSA:1.10.10.10 131 232 4.4E-32 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 PANTHER PTHR26402:SF50 5 233 1.1E-73 T 09-11-2016 CLOSPO_RS13445 efa23655e334451a9ffa3c2077d7ff88 233 SUPERFAMILY SSF52172 5 181 9.59E-34 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS14240 db528cf6bda3087b526e7637cf767647 114 Gene3D G3DSA:1.10.10.10 4 104 9.4E-30 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14240 db528cf6bda3087b526e7637cf767647 114 PANTHER PTHR33169:SF1 1 104 2.0E-53 T 09-11-2016 CLOSPO_RS14240 db528cf6bda3087b526e7637cf767647 114 Pfam PF03551 Transcriptional regulator PadR-like family 16 86 2.4E-21 T 09-11-2016 IPR005149 Transcription regulator PadR, N-terminal CLOSPO_RS14240 db528cf6bda3087b526e7637cf767647 114 PANTHER PTHR33169 1 104 2.0E-53 T 09-11-2016 CLOSPO_RS14240 db528cf6bda3087b526e7637cf767647 114 SUPERFAMILY SSF46785 6 104 6.13E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 Gene3D G3DSA:3.50.50.60 136 333 6.8E-49 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 SUPERFAMILY SSF55424 340 460 3.26E-40 T 09-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 1.9E-70 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 Gene3D G3DSA:3.50.50.60 3 135 1.5E-43 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PANTHER PTHR22912 3 454 3.2E-183 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 9.8E-34 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 9.8E-34 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 9.8E-34 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 9.8E-34 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.8E-34 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 Gene3D G3DSA:3.30.390.30 334 460 8.3E-45 T 09-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PIRSF PIRSF000350 1 460 1.0E-92 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 324 1.1E-61 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 460 3.3E-156 T 09-11-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 09-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 SUPERFAMILY SSF51905 3 318 5.18E-53 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 PANTHER PTHR22912:SF20 3 454 3.2E-183 T 09-11-2016 CLOSPO_RS16965 142bb5f464f8cb5d7f5e228cf1d03ce9 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 450 2.7E-36 T 09-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOSPO_RS15990 aeadc79d432708ccf87a8ce0c6052cad 449 PANTHER PTHR11785 2 441 3.0E-191 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS15990 aeadc79d432708ccf87a8ce0c6052cad 449 Pfam PF13520 Amino acid permease 11 414 3.5E-59 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS15990 aeadc79d432708ccf87a8ce0c6052cad 449 PANTHER PTHR11785:SF259 2 441 3.0E-191 T 09-11-2016 CLOSPO_RS15990 aeadc79d432708ccf87a8ce0c6052cad 449 PIRSF PIRSF006060 1 449 3.2E-74 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 Pfam PF06165 Glycosyltransferase family 36 299 373 5.1E-19 T 09-11-2016 IPR010383 Glycosyl hydrolase 94 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 Pfam PF10091 Putative glucoamylase 35 249 1.0E-18 T 09-11-2016 IPR019282 Domain of unknown function DUF2329 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 Gene3D G3DSA:2.70.98.40 286 373 1.5E-30 T 09-11-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 PANTHER PTHR37469 1 373 1.5E-227 T 09-11-2016 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 PANTHER PTHR37469:SF2 1 373 1.5E-227 T 09-11-2016 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 SUPERFAMILY SSF74650 289 373 1.69E-21 T 09-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CLOSPO_RS07885 31363aa6c1a01badb5e7596ac330aa7d 374 SMART SM01068 277 336 1.4E-12 T 09-11-2016 IPR009342 Putative carbohydrate binding domain CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 Gene3D G3DSA:3.40.50.620 1 258 1.7E-85 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 SUPERFAMILY SSF52402 1 257 1.19E-75 T 09-11-2016 CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 PANTHER PTHR21294:SF0 1 262 6.7E-92 T 09-11-2016 CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 SMART SM00893 22 213 7.0E-58 T 09-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 Pfam PF01012 Electron transfer flavoprotein domain 22 202 2.9E-45 T 09-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 PIRSF PIRSF000090 1 262 1.2E-85 T 09-11-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 CLOSPO_RS18465 aa6402088b3f1212cfee5924660e564d 262 PANTHER PTHR21294 1 262 6.7E-92 T 09-11-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 1 185 2.6E-63 T 09-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 PANTHER PTHR11946:SF5 1 185 2.1E-105 T 09-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 Gene3D G3DSA:3.90.740.10 114 185 6.6E-30 T 09-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 SUPERFAMILY SSF50677 105 185 2.09E-37 T 09-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 PANTHER PTHR11946 1 185 2.1E-105 T 09-11-2016 CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 Gene3D G3DSA:3.40.50.620 2 113 1.2E-33 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS08730 116a27ccefb1162e7bbd25712b5bff33 185 SUPERFAMILY SSF52374 4 118 8.84E-32 T 09-11-2016 CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 17 296 1.0E-77 T 09-11-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 PANTHER PTHR10803:SF0 6 368 2.4E-113 T 09-11-2016 CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 SUPERFAMILY SSF52540 312 546 3.55E-41 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 PIRSF PIRSF001327 2 581 8.8E-273 T 09-11-2016 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 12 569 9.4E-260 T 09-11-2016 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 SUPERFAMILY SSF52540 14 291 2.39E-50 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 SMART SM00382 12 234 4.7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 SMART SM00382 325 519 0.31 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 PANTHER PTHR10803 6 368 2.4E-113 T 09-11-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 Pfam PF02374 Anion-transporting ATPase 13 295 7.5E-79 T 09-11-2016 IPR025723 Anion-transporting ATPase-like domain CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 Pfam PF02374 Anion-transporting ATPase 327 468 2.8E-31 T 09-11-2016 IPR025723 Anion-transporting ATPase-like domain CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 Pfam PF02374 Anion-transporting ATPase 474 573 7.6E-7 T 09-11-2016 IPR025723 Anion-transporting ATPase-like domain CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 Gene3D G3DSA:3.40.50.300 13 288 7.8E-77 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17190 bac396809b33f1ceace609723ef137fc 581 Gene3D G3DSA:3.40.50.300 313 573 4.3E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14720 dcb3756f4a92319711943278f05979ea 61 PANTHER PTHR39341 2 60 2.6E-23 T 09-11-2016 CLOSPO_RS14720 dcb3756f4a92319711943278f05979ea 61 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 3 60 7.8E-30 T 09-11-2016 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide CLOSPO_RS14720 dcb3756f4a92319711943278f05979ea 61 Pfam PF08984 Domain of unknown function (DUF1858) 3 56 1.5E-24 T 09-11-2016 IPR015077 Domain of unknown function DUF1858 CLOSPO_RS14720 dcb3756f4a92319711943278f05979ea 61 SUPERFAMILY SSF140683 1 61 2.22E-20 T 09-11-2016 CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 PIRSF PIRSF004869 1 291 5.2E-77 T 09-11-2016 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 Pfam PF04055 Radical SAM superfamily 56 224 1.5E-11 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 SUPERFAMILY SSF102114 60 190 2.94E-11 T 09-11-2016 CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 PANTHER PTHR30352:SF7 1 281 2.2E-136 T 09-11-2016 CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 Gene3D G3DSA:3.20.20.70 59 277 1.3E-12 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 Pfam PF13353 4Fe-4S single cluster domain 55 152 8.0E-6 T 09-11-2016 CLOSPO_RS15075 0373359d9bdd9113c70ec89cefa6ed7e 298 PANTHER PTHR30352 1 281 2.2E-136 T 09-11-2016 CLOSPO_RS12885 627c14a8714548223c1f6b79e2068869 224 Pfam PF09335 SNARE associated Golgi protein 67 183 5.4E-31 T 09-11-2016 IPR032816 SNARE associated Golgi protein CLOSPO_RS12885 627c14a8714548223c1f6b79e2068869 224 PANTHER PTHR12677 1 223 4.9E-43 T 09-11-2016 IPR015414 Transmembrane protein TMEM64/TMEM41 GO:0016021 CLOSPO_RS12885 627c14a8714548223c1f6b79e2068869 224 PANTHER PTHR12677:SF5 1 223 4.9E-43 T 09-11-2016 CLOSPO_RS06550 5c535238b2adfc7e63592cc193f6a474 222 Gene3D G3DSA:3.50.50.60 161 221 3.8E-9 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS06550 5c535238b2adfc7e63592cc193f6a474 222 PANTHER PTHR22912:SF141 1 222 1.4E-100 T 09-11-2016 CLOSPO_RS06550 5c535238b2adfc7e63592cc193f6a474 222 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 218 1.5E-18 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS06550 5c535238b2adfc7e63592cc193f6a474 222 SUPERFAMILY SSF51905 1 219 8.8E-30 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS06550 5c535238b2adfc7e63592cc193f6a474 222 PANTHER PTHR22912 1 222 1.4E-100 T 09-11-2016 CLOSPO_RS06550 5c535238b2adfc7e63592cc193f6a474 222 Gene3D G3DSA:3.40.50.720 1 160 2.4E-28 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14425 56d35ce58c0d746279f3f5320a8dfa48 246 Pfam PF05175 Methyltransferase small domain 35 172 1.1E-9 T 09-11-2016 IPR007848 Methyltransferase small domain GO:0008168 CLOSPO_RS14425 56d35ce58c0d746279f3f5320a8dfa48 246 Gene3D G3DSA:3.40.50.150 33 243 1.9E-66 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14425 56d35ce58c0d746279f3f5320a8dfa48 246 SUPERFAMILY SSF53335 8 210 2.72E-31 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14425 56d35ce58c0d746279f3f5320a8dfa48 246 PANTHER PTHR18895:SF75 1 240 1.3E-91 T 09-11-2016 CLOSPO_RS14425 56d35ce58c0d746279f3f5320a8dfa48 246 PANTHER PTHR18895 1 240 1.3E-91 T 09-11-2016 CLOSPO_RS07685 395a0a82ce20e2310372be4d13b530ea 216 PANTHER PTHR33989:SF4 1 216 1.1E-99 T 09-11-2016 CLOSPO_RS07685 395a0a82ce20e2310372be4d13b530ea 216 Pfam PF02378 Phosphotransferase system, EIIC 1 178 6.8E-34 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS07685 395a0a82ce20e2310372be4d13b530ea 216 PANTHER PTHR33989 1 216 1.1E-99 T 09-11-2016 CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 Gene3D G3DSA:3.40.50.360 4 141 8.9E-6 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 Gene3D G3DSA:3.30.70.20 143 196 2.9E-5 T 09-11-2016 CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 SUPERFAMILY SSF54862 182 243 7.06E-14 T 09-11-2016 CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 216 227 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 Gene3D G3DSA:3.30.70.20 197 243 2.4E-11 T 09-11-2016 CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 PANTHER PTHR24960 4 234 1.8E-17 T 09-11-2016 CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 Pfam PF00037 4Fe-4S binding domain 185 204 1.7E-4 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 PANTHER PTHR24960:SF31 4 234 1.8E-17 T 09-11-2016 CLOSPO_RS13460 29a5bc9a8c8746d060df3c5441c4b45e 250 SUPERFAMILY SSF52218 4 112 4.19E-11 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS14455 f8ec59420609fadbea60e892d5df11e1 231 PANTHER PTHR10344 1 226 2.3E-41 T 09-11-2016 CLOSPO_RS14455 f8ec59420609fadbea60e892d5df11e1 231 Hamap MF_00165 Thymidylate kinase [tmk]. 5 225 12.591 T 09-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 CLOSPO_RS14455 f8ec59420609fadbea60e892d5df11e1 231 SUPERFAMILY SSF52540 1 227 2.9E-35 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14455 f8ec59420609fadbea60e892d5df11e1 231 Gene3D G3DSA:3.40.50.300 1 226 1.4E-46 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14455 f8ec59420609fadbea60e892d5df11e1 231 Pfam PF02223 Thymidylate kinase 9 190 1.3E-17 T 09-11-2016 CLOSPO_RS17985 620e4797f7d59481485dccdf4921e13d 362 Pfam PF00155 Aminotransferase class I and II 16 356 2.1E-32 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS17985 620e4797f7d59481485dccdf4921e13d 362 PANTHER PTHR11751 2 362 5.5E-173 T 09-11-2016 CLOSPO_RS17985 620e4797f7d59481485dccdf4921e13d 362 PANTHER PTHR11751:SF338 2 362 5.5E-173 T 09-11-2016 CLOSPO_RS17985 620e4797f7d59481485dccdf4921e13d 362 Gene3D G3DSA:3.90.1150.10 260 361 7.2E-29 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS17985 620e4797f7d59481485dccdf4921e13d 362 Gene3D G3DSA:3.40.640.10 30 259 1.7E-65 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS17985 620e4797f7d59481485dccdf4921e13d 362 SUPERFAMILY SSF53383 11 360 3.74E-63 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS16010 a643343e0010ba6c093c5dd81ad3b5ac 178 PANTHER PTHR33567 3 178 1.1E-66 T 09-11-2016 CLOSPO_RS16010 a643343e0010ba6c093c5dd81ad3b5ac 178 Pfam PF02417 Chromate transporter 5 170 2.5E-49 T 09-11-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 PRINTS PR00354 7Fe ferredoxin signature 17 27 4.7E-5 T 09-11-2016 IPR000813 7Fe ferredoxin GO:0009055 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 PRINTS PR00354 7Fe ferredoxin signature 33 50 4.7E-5 T 09-11-2016 IPR000813 7Fe ferredoxin GO:0009055 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 SUPERFAMILY SSF54862 3 54 2.33E-18 T 09-11-2016 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 Gene3D G3DSA:3.30.70.20 5 53 1.2E-17 T 09-11-2016 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 PANTHER PTHR24960:SF38 1 50 1.1E-12 T 09-11-2016 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 PANTHER PTHR24960 1 50 1.1E-12 T 09-11-2016 CLOSPO_RS14430 64805280bbcafe3b1a4e9bf8a88070b1 56 Pfam PF12838 4Fe-4S dicluster domain 8 52 1.9E-10 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Gene3D G3DSA:1.10.150.20 88 134 1.3E-6 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 PANTHER PTHR10887 659 741 3.6E-133 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 SUPERFAMILY SSF52540 312 711 1.46E-63 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Pfam PF14520 Helix-hairpin-helix domain 88 133 2.0E-8 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Pfam PF13604 AAA domain 320 514 5.3E-48 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 735 28.603 T 09-11-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 SMART SM00382 332 516 6.7E-5 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 4 728 3.6E-211 T 09-11-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 SMART SM00278 81 102 920.0 T 09-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 SMART SM00278 116 135 2.1 T 09-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 SMART SM00278 180 199 310.0 T 09-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Pfam PF13538 UvrD-like helicase C-terminal domain 659 706 2.2E-17 T 09-11-2016 IPR027785 UvrD-like helicase C-terminal domain CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 PANTHER PTHR10887 105 170 3.6E-133 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 PANTHER PTHR10887 316 577 3.6E-133 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Gene3D G3DSA:3.40.50.300 141 158 7.9E-18 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Gene3D G3DSA:3.40.50.300 653 728 7.9E-18 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 PANTHER PTHR10887:SF284 105 170 3.6E-133 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 PANTHER PTHR10887:SF284 659 741 3.6E-133 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 PANTHER PTHR10887:SF284 316 577 3.6E-133 T 09-11-2016 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 SUPERFAMILY SSF47781 80 156 4.0E-11 T 09-11-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Pfam PF14490 Helix-hairpin-helix containing domain 138 228 3.9E-32 T 09-11-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain CLOSPO_RS13865 dab83b84380823d5fc4161c7cce49706 744 Gene3D G3DSA:3.40.50.300 284 501 9.9E-51 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PANTHER PTHR30511 3 390 1.3E-181 T 09-11-2016 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 Hamap MF_01201 Alanine racemase. 5 385 35.349 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 35 45 - T 09-11-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 Gene3D G3DSA:3.20.20.10 14 233 7.7E-73 T 09-11-2016 IPR029066 PLP-binding barrel CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 SMART SM01005 254 385 1.7E-69 T 09-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 Pfam PF00842 Alanine racemase, C-terminal domain 255 384 2.6E-42 T 09-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 TIGRFAM TIGR00492 alr: alanine racemase 6 385 3.0E-122 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PANTHER PTHR30511:SF0 3 390 1.3E-181 T 09-11-2016 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 66 84 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 270 285 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 30 46 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 213 240 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 287 302 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 367 380 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 PRINTS PR00992 Alanine racemase signature 170 181 5.6E-47 T 09-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 SUPERFAMILY SSF51419 12 255 4.22E-64 T 09-11-2016 IPR029066 PLP-binding barrel CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 Pfam PF01168 Alanine racemase, N-terminal domain 12 240 1.1E-62 T 09-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 Gene3D G3DSA:2.40.37.10 234 392 1.4E-60 T 09-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 CLOSPO_RS13250 f0b09908069e1b283a387196c9d1d0eb 402 SUPERFAMILY SSF50621 247 391 2.44E-49 T 09-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Pfam PF00308 Bacterial dnaA protein 111 328 7.1E-104 T 09-11-2016 IPR013317 Chromosomal replication initiator protein DnaA CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 SUPERFAMILY SSF48295 342 447 2.88E-39 T 09-11-2016 IPR010921 Trp repressor/replication initiator GO:0043565 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 09-11-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 SMART SM00382 143 271 2.3E-8 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 446 35.027 T 09-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Gene3D G3DSA:3.40.50.300 100 274 3.5E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 SUPERFAMILY SSF52540 111 323 5.68E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 SMART SM00760 355 424 9.8E-46 T 09-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PANTHER PTHR30050:SF2 4 448 2.1E-244 T 09-11-2016 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 445 2.8E-186 T 09-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Gene3D G3DSA:1.10.8.60 277 345 1.5E-31 T 09-11-2016 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 424 2.7E-33 T 09-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PANTHER PTHR30050 4 448 2.1E-244 T 09-11-2016 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Pfam PF11638 DnaA N-terminal domain 7 67 1.2E-13 T 09-11-2016 IPR024633 DnaA N-terminal domain CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 Gene3D G3DSA:1.10.1750.10 346 447 5.6E-44 T 09-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 6.1E-53 T 09-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 6.1E-53 T 09-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 6.1E-53 T 09-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 6.1E-53 T 09-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like CLOSPO_RS14545 1f438cc10410d82ab87951f59e9f06ee 448 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 6.1E-53 T 09-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like CLOSPO_RS15535 f5da478d0f55df32fa6525e5565ea9a5 152 SUPERFAMILY SSF54593 1 118 1.51E-19 T 09-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOSPO_RS15535 f5da478d0f55df32fa6525e5565ea9a5 152 Pfam PF12681 Glyoxalase-like domain 3 121 7.8E-53 T 09-11-2016 IPR025870 Glyoxalase-like domain CLOSPO_RS15535 f5da478d0f55df32fa6525e5565ea9a5 152 Gene3D G3DSA:3.10.180.10 8 125 8.5E-24 T 09-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 129 263 4.4E-36 T 09-11-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 263 7.1E-77 T 09-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 124 4.9E-35 T 09-11-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 PANTHER PTHR20836:SF0 1 265 1.0E-85 T 09-11-2016 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 SUPERFAMILY SSF51735 1 126 1.43E-39 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 SUPERFAMILY SSF51735 235 265 1.43E-39 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 SUPERFAMILY SSF55347 129 234 1.07E-27 T 09-11-2016 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 PIRSF PIRSF000161 1 265 8.8E-72 T 09-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 PANTHER PTHR20836 1 265 1.0E-85 T 09-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 Gene3D G3DSA:3.40.50.720 1 163 7.2E-49 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 264 28.479 T 09-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS17435 fcb00f59501d6ca638e17e04483458b1 265 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 09-11-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 09-11-2016 IPR020081 SsrA-binding protein, conserved site CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 151 1.9E-58 T 09-11-2016 IPR000037 SsrA-binding protein GO:0003723 CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 76.684 T 09-11-2016 IPR000037 SsrA-binding protein GO:0003723 CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 PANTHER PTHR30308 1 156 1.8E-84 T 09-11-2016 CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 Gene3D G3DSA:2.40.280.10 9 128 1.1E-54 T 09-11-2016 IPR023620 Small protein B CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 11 133 1.0E-60 T 09-11-2016 IPR000037 SsrA-binding protein GO:0003723 CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 SUPERFAMILY SSF74982 3 133 1.19E-54 T 09-11-2016 IPR023620 Small protein B CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 PANTHER PTHR30308:SF2 1 156 1.8E-84 T 09-11-2016 CLOSPO_RS13535 2307f0299100e605df2f579dddbd2a53 156 Pfam PF01668 SmpB protein 10 73 2.2E-34 T 09-11-2016 IPR000037 SsrA-binding protein GO:0003723 CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 PANTHER PTHR34405:SF1 1 81 6.8E-23 T 09-11-2016 CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 SUPERFAMILY SSF143430 1 83 3.27E-26 T 09-11-2016 CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 Gene3D G3DSA:3.30.70.240 1 65 1.2E-25 T 09-11-2016 IPR000640 Translation elongation factor EFG, V domain CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 15.078 T 09-11-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 PANTHER PTHR34405 1 81 6.8E-23 T 09-11-2016 CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 Pfam PF09827 CRISPR associated protein Cas2 1 70 5.7E-22 T 09-11-2016 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CLOSPO_RS17430 f8fe3af16860c22c25accdf993fa9203 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 83 6.1E-15 T 09-11-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CLOSPO_RS12910 1f50806c0a2f40c38b1858d67ec3817a 269 SUPERFAMILY SSF88713 51 266 2.97E-50 T 09-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOSPO_RS12910 1f50806c0a2f40c38b1858d67ec3817a 269 Gene3D G3DSA:3.20.20.370 68 268 1.8E-56 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS12910 1f50806c0a2f40c38b1858d67ec3817a 269 Gene3D G3DSA:3.20.20.370 7 36 1.8E-56 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS12910 1f50806c0a2f40c38b1858d67ec3817a 269 PANTHER PTHR10587:SF15 69 268 2.3E-46 T 09-11-2016 CLOSPO_RS12910 1f50806c0a2f40c38b1858d67ec3817a 269 PANTHER PTHR10587 69 268 2.3E-46 T 09-11-2016 CLOSPO_RS12910 1f50806c0a2f40c38b1858d67ec3817a 269 Pfam PF01522 Polysaccharide deacetylase 74 186 6.8E-28 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 Pfam PF12833 Helix-turn-helix domain 28 105 1.7E-19 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 Gene3D G3DSA:1.10.10.60 4 56 3.1E-16 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 SUPERFAMILY SSF46689 5 53 4.48E-7 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 Gene3D G3DSA:1.10.10.60 57 117 1.6E-20 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 57 99 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 SMART SM00342 20 103 3.0E-25 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 SUPERFAMILY SSF46689 56 114 1.61E-13 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 PANTHER PTHR11019 1 111 2.8E-57 T 09-11-2016 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 72 87 1.8E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 87 103 1.8E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS14995 0bcca098cf2bf84ae477da7643300589 128 PANTHER PTHR11019:SF128 1 111 2.8E-57 T 09-11-2016 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 PANTHER PTHR10882:SF3 12 125 3.2E-12 T 09-11-2016 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 SUPERFAMILY SSF53790 12 209 2.47E-39 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 PANTHER PTHR10882 12 125 3.2E-12 T 09-11-2016 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 15 207 6.7E-60 T 09-11-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 12 195 3.0E-25 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 Gene3D G3DSA:3.40.1010.10 11 112 2.1E-24 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS18095 accf27abfaacf989e4aec5496564f234 215 Gene3D G3DSA:3.30.950.10 113 209 3.9E-20 T 09-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 Pfam PF00704 Glycosyl hydrolases family 18 54 451 1.9E-80 T 09-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 PANTHER PTHR11177:SF215 133 523 3.4E-187 T 09-11-2016 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 SUPERFAMILY SSF49384 504 608 1.53E-12 T 09-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 SUPERFAMILY SSF54556 338 422 5.04E-19 T 09-11-2016 IPR029070 Chitinase insertion domain CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 Gene3D G3DSA:3.10.50.10 340 422 4.1E-17 T 09-11-2016 IPR029070 Chitinase insertion domain CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 Gene3D G3DSA:3.20.20.80 45 339 1.4E-88 T 09-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 Gene3D G3DSA:3.20.20.80 428 457 1.4E-88 T 09-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 PANTHER PTHR11177 49 107 3.4E-187 T 09-11-2016 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 PANTHER PTHR11177 133 523 3.4E-187 T 09-11-2016 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 SUPERFAMILY SSF51445 51 338 1.26E-79 T 09-11-2016 IPR017853 Glycoside hydrolase superfamily CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 SUPERFAMILY SSF51445 423 453 1.26E-79 T 09-11-2016 IPR017853 Glycoside hydrolase superfamily CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 ProSitePatterns PS01095 Chitinases family 18 active site. 189 197 - T 09-11-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 Gene3D G3DSA:2.60.40.290 518 587 2.5E-7 T 09-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 Pfam PF06483 Chitinase C 469 599 7.8E-8 T 09-11-2016 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902|UniPathway: UPA00349 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 PANTHER PTHR11177:SF215 49 107 3.4E-187 T 09-11-2016 CLOSPO_RS17085 386248fe4291ba87a22bb91ccfb794cc 617 SMART SM00636 52 451 7.9E-116 T 09-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 Pfam PF00330 Aconitase family (aconitate hydratase) 1 239 1.4E-68 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 ProSitePatterns PS01244 Aconitase family signature 2. 181 194 - T 09-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 PRINTS PR00415 Aconitase family signature 32 45 8.2E-10 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 PRINTS PR00415 Aconitase family signature 18 31 8.2E-10 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 PRINTS PR00415 Aconitase family signature 181 194 8.2E-10 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 PANTHER PTHR11670:SF30 1 333 2.2E-133 T 09-11-2016 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 Gene3D G3DSA:3.20.19.10 292 337 1.0E-8 T 09-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 PANTHER PTHR11670 1 333 2.2E-133 T 09-11-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 SUPERFAMILY SSF52016 268 339 5.89E-13 T 09-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 SUPERFAMILY SSF53732 1 250 2.09E-96 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 Gene3D G3DSA:3.40.1060.10 1 94 1.6E-32 T 09-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 Gene3D G3DSA:3.30.499.10 102 291 3.2E-59 T 09-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS03120 2a84e6e7ed72eeaf63214ac415059ec0 341 ProSitePatterns PS00450 Aconitase family signature 1. 121 137 - T 09-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 Gene3D G3DSA:3.90.550.10 363 606 1.9E-31 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 Pfam PF00534 Glycosyl transferases group 1 144 269 2.1E-17 T 09-11-2016 IPR001296 Glycosyl transferase, family 1 CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 SUPERFAMILY SSF53756 25 308 2.51E-37 T 09-11-2016 CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 PANTHER PTHR22916 308 606 5.1E-30 T 09-11-2016 CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 SUPERFAMILY SSF53448 362 621 3.56E-33 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 Gene3D G3DSA:3.40.50.2000 149 270 3.9E-10 T 09-11-2016 CLOSPO_RS18800 ee3a1b213b2752c339d0a8e2696c8a02 696 Pfam PF00535 Glycosyl transferase family 2 364 483 1.4E-14 T 09-11-2016 IPR001173 Glycosyltransferase 2-like CLOSPO_RS00630 4bcebb81a0de44e0ddc7ca524d1a750b 130 Pfam PF03984 Repeat of unknown function (DUF346) 75 109 5.4E-6 T 09-11-2016 IPR007132 Protein of unknown function DUF346 CLOSPO_RS00630 4bcebb81a0de44e0ddc7ca524d1a750b 130 Gene3D G3DSA:2.120.10.70 35 130 1.5E-23 T 09-11-2016 CLOSPO_RS00630 4bcebb81a0de44e0ddc7ca524d1a750b 130 SUPERFAMILY SSF89372 48 130 1.96E-16 T 09-11-2016 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PANTHER PTHR10264 1 303 2.4E-108 T 09-11-2016 IPR001972 Stomatin family GO:0016020 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 SUPERFAMILY SSF117892 49 183 1.23E-40 T 09-11-2016 IPR001107 Band 7 domain CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 SMART SM00244 18 176 1.4E-51 T 09-11-2016 IPR001107 Band 7 domain CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PRINTS PR00721 Stomatin signature 128 151 3.6E-26 T 09-11-2016 IPR001972 Stomatin family GO:0016020 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PRINTS PR00721 Stomatin signature 171 192 3.6E-26 T 09-11-2016 IPR001972 Stomatin family GO:0016020 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PRINTS PR00721 Stomatin signature 108 125 3.6E-26 T 09-11-2016 IPR001972 Stomatin family GO:0016020 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PRINTS PR00721 Stomatin signature 73 94 3.6E-26 T 09-11-2016 IPR001972 Stomatin family GO:0016020 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PRINTS PR00721 Stomatin signature 152 170 3.6E-26 T 09-11-2016 IPR001972 Stomatin family GO:0016020 CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 Pfam PF01145 SPFH domain / Band 7 family 22 192 3.0E-37 T 09-11-2016 IPR001107 Band 7 domain CLOSPO_RS16040 78e67386d1ad7ac1d73537cf6b689d4b 312 PANTHER PTHR10264:SF27 1 303 2.4E-108 T 09-11-2016 CLOSPO_RS12925 a98d16f73df9d30b2ab6fd7f1da07df0 175 Gene3D G3DSA:1.20.144.10 5 173 5.8E-41 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS12925 a98d16f73df9d30b2ab6fd7f1da07df0 175 SMART SM00014 57 167 2.6E-24 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS12925 a98d16f73df9d30b2ab6fd7f1da07df0 175 Pfam PF01569 PAP2 superfamily 62 174 1.5E-26 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS12925 a98d16f73df9d30b2ab6fd7f1da07df0 175 PANTHER PTHR14969 1 174 4.6E-36 T 09-11-2016 CLOSPO_RS12925 a98d16f73df9d30b2ab6fd7f1da07df0 175 SUPERFAMILY SSF48317 4 173 2.22E-42 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 SUPERFAMILY SSF52402 2 211 3.72E-55 T 09-11-2016 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 PANTHER PTHR11807 1 462 2.3E-105 T 09-11-2016 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 206 6.5E-58 T 09-11-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 PANTHER PTHR11807:SF2 1 462 2.3E-105 T 09-11-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 SMART SM00977 384 456 5.5E-28 T 09-11-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 Gene3D G3DSA:3.40.50.620 1 184 2.4E-18 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 Pfam PF01171 PP-loop family 20 201 1.7E-51 T 09-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 384 430 1.3E-19 T 09-11-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 Pfam PF11734 TilS substrate C-terminal domain 386 453 1.2E-16 T 09-11-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 SUPERFAMILY SSF82829 215 319 2.54E-10 T 09-11-2016 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 SUPERFAMILY SSF56037 373 457 1.27E-24 T 09-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CLOSPO_RS15265 961816aecad1664a952ef6b2d7ca1ee6 468 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 12 296 23.917 T 09-11-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOSPO_RS18365 ebaa5735ce001fa30b2be5f359979c3e 163 Gene3D G3DSA:2.40.128.20 61 135 1.6E-4 T 09-11-2016 IPR012674 Calycin CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 Pfam PF01043 SecA preprotein cross-linking domain 111 214 2.1E-37 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 SUPERFAMILY SSF52540 1 122 3.54E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 Pfam PF07517 SecA DEAD-like domain 1 161 2.7E-59 T 09-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 SMART SM00958 107 214 2.7E-54 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 SUPERFAMILY SSF81767 106 214 3.27E-37 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 Gene3D G3DSA:3.90.1440.10 112 214 2.9E-37 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 Gene3D G3DSA:3.40.50.300 1 111 1.3E-50 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 PRINTS PR00906 SecA protein signature 200 214 8.9E-16 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 PRINTS PR00906 SecA protein signature 49 69 8.9E-16 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 SMART SM00957 1 214 7.5E-74 T 09-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CLOSPO_RS01490 a7a6b9b163137e21e57ce9f30ba237a1 214 PANTHER PTHR30612 1 214 7.8E-102 T 09-11-2016 CLOSPO_RS12615 de23538d2a782234e0730c07a7a112a9 201 PANTHER PTHR11019 4 158 5.5E-41 T 09-11-2016 CLOSPO_RS12615 de23538d2a782234e0730c07a7a112a9 201 PANTHER PTHR11019:SF124 4 158 5.5E-41 T 09-11-2016 CLOSPO_RS12615 de23538d2a782234e0730c07a7a112a9 201 Pfam PF01965 DJ-1/PfpI family 4 167 5.3E-24 T 09-11-2016 IPR002818 DJ-1/PfpI CLOSPO_RS12615 de23538d2a782234e0730c07a7a112a9 201 Gene3D G3DSA:3.40.50.880 4 199 8.1E-51 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS12615 de23538d2a782234e0730c07a7a112a9 201 SUPERFAMILY SSF52317 3 187 3.93E-41 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 Gene3D G3DSA:3.40.50.300 419 584 4.4E-10 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 Gene3D G3DSA:1.10.3210.10 35 134 2.4E-5 T 09-11-2016 IPR006674 HD domain CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 Gene3D G3DSA:3.40.50.300 202 385 7.3E-12 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 PANTHER PTHR24031:SF299 586 736 9.3E-17 T 09-11-2016 CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 PANTHER PTHR24031:SF299 341 541 9.3E-17 T 09-11-2016 CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 12 187 1.3E-21 T 09-11-2016 IPR006483 CRISPR-associated Cas3-HD domain CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 Pfam PF00271 Helicase conserved C-terminal domain 422 532 9.5E-7 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 SUPERFAMILY SSF52540 225 533 1.42E-27 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 PANTHER PTHR24031 586 736 9.3E-17 T 09-11-2016 CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 PANTHER PTHR24031 341 541 9.3E-17 T 09-11-2016 CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 Pfam PF00270 DEAD/DEAH box helicase 222 380 1.3E-5 T 09-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 Pfam PF01966 HD domain 21 117 2.7E-4 T 09-11-2016 IPR006674 HD domain CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 230 544 1.0E-73 T 09-11-2016 IPR006474 Helicase Cas3, CRISPR-associated, core CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 SUPERFAMILY SSF109604 33 120 9.87E-6 T 09-11-2016 CLOSPO_RS17415 1ad516c4f3c26bda1a91c174a4732c39 750 SMART SM00487 210 406 8.4E-5 T 09-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.3E-19 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 PANTHER PTHR30126 1 298 1.8E-117 T 09-11-2016 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 Gene3D G3DSA:3.40.190.10 91 190 1.1E-15 T 09-11-2016 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 SUPERFAMILY SSF53850 91 295 7.9E-30 T 09-11-2016 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 Gene3D G3DSA:3.40.190.10 191 249 8.5E-12 T 09-11-2016 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 PANTHER PTHR30126:SF13 1 298 1.8E-117 T 09-11-2016 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-9 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-9 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-9 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 Gene3D G3DSA:1.10.10.10 1 78 1.4E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 SUPERFAMILY SSF46785 1 87 5.45E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14895 23969da4da9f2b7ff7b3d64e067f578e 301 Pfam PF03466 LysR substrate binding domain 89 293 5.2E-31 T 09-11-2016 IPR005119 LysR, substrate-binding CLOSPO_RS18485 feb03ecd2cdea74ab7f302632fb735c1 426 SUPERFAMILY SSF55890 232 280 4.18E-5 T 09-11-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CLOSPO_RS18485 feb03ecd2cdea74ab7f302632fb735c1 426 SUPERFAMILY SSF55874 288 416 1.41E-7 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18485 feb03ecd2cdea74ab7f302632fb735c1 426 Gene3D G3DSA:3.30.565.10 290 420 1.4E-4 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18485 feb03ecd2cdea74ab7f302632fb735c1 426 Gene3D G3DSA:1.10.287.130 225 279 1.1E-4 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18485 feb03ecd2cdea74ab7f302632fb735c1 426 Pfam PF14501 GHKL domain 324 423 4.3E-26 T 09-11-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 PANTHER PTHR10804 112 360 8.2E-80 T 09-11-2016 CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 SUPERFAMILY SSF53092 3 130 4.01E-12 T 09-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 PANTHER PTHR10804 13 22 8.2E-80 T 09-11-2016 CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 Gene3D G3DSA:3.40.350.10 2 129 1.8E-12 T 09-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 SUPERFAMILY SSF55920 133 360 3.4E-70 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 Pfam PF00557 Metallopeptidase family M24 138 343 1.7E-58 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 Gene3D G3DSA:3.90.230.10 130 360 2.7E-80 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 130 1.5E-13 T 09-11-2016 IPR000587 Creatinase, N-terminal GO:0016787 CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 PANTHER PTHR10804:SF86 13 22 8.2E-80 T 09-11-2016 CLOSPO_RS12955 923dc961801ffb145e5288a1968fe572 360 PANTHER PTHR10804:SF86 112 360 8.2E-80 T 09-11-2016 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 SUPERFAMILY SSF53383 95 481 2.85E-83 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 Gene3D G3DSA:1.10.10.10 3 77 1.3E-23 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 Gene3D G3DSA:3.40.640.10 148 362 1.4E-70 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 PANTHER PTHR11751:SF357 95 482 3.6E-94 T 09-11-2016 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 Gene3D G3DSA:3.90.1150.10 363 470 3.7E-7 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 SMART SM00345 17 76 4.2E-17 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 6.3E-17 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 SUPERFAMILY SSF46785 10 78 2.94E-19 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 Pfam PF00155 Aminotransferase class I and II 134 468 2.1E-28 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS17645 be0f99cbc13c35b6e111d72f0d63d225 497 PANTHER PTHR11751 95 482 3.6E-94 T 09-11-2016 CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 SMART SM00382 26 208 1.2E-14 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 PANTHER PTHR24220 4 279 3.9E-105 T 09-11-2016 CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 Pfam PF00005 ABC transporter 19 161 1.6E-30 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 Gene3D G3DSA:3.40.50.300 2 222 8.2E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 PANTHER PTHR24220:SF331 4 279 3.9E-105 T 09-11-2016 CLOSPO_RS16350 7e78ca3c83d6c052ed0fe892ee24370d 291 SUPERFAMILY SSF52540 3 226 2.72E-60 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 Gene3D G3DSA:1.10.10.60 63 121 7.0E-21 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 78 93 7.2E-8 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 93 109 7.2E-8 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 PANTHER PTHR11019 11 117 9.3E-24 T 09-11-2016 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 PANTHER PTHR11019:SF84 11 117 9.3E-24 T 09-11-2016 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 SMART SM00342 26 109 7.2E-27 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 Gene3D G3DSA:1.10.10.60 4 62 2.9E-10 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 SUPERFAMILY SSF46689 63 115 3.58E-13 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17005 4503d574b352ad7fd3daef6b016a39e1 321 Pfam PF12833 Helix-turn-helix domain 32 110 1.7E-20 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 SMART SM00304 198 250 2.7E-10 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 312 8.9E-8 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PANTHER PTHR24423:SF470 1 128 1.4E-163 T 09-11-2016 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PANTHER PTHR24423:SF470 192 461 1.4E-163 T 09-11-2016 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 Pfam PF00672 HAMP domain 179 246 1.2E-14 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 SMART SM00388 251 316 9.4E-6 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PANTHER PTHR24423 1 128 1.4E-163 T 09-11-2016 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 Gene3D G3DSA:3.30.565.10 326 460 1.2E-23 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 Gene3D G3DSA:1.10.287.130 241 310 3.7E-10 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 7.4E-5 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 7.4E-5 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 7.4E-5 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 PANTHER PTHR24423 192 461 1.4E-163 T 09-11-2016 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 SUPERFAMILY SSF47384 234 311 1.57E-12 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 SUPERFAMILY SSF55874 326 460 5.63E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 SUPERFAMILY SSF158472 199 247 1.96E-9 T 09-11-2016 CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 457 2.5E-12 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13145 d308542d827994cac1c3d16a69a1ca3a 461 SMART SM00387 359 460 2.3E-16 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13235 1a11ae46ce0726e4d5db4278cd484b69 169 PANTHER PTHR30175 14 120 1.9E-44 T 09-11-2016 CLOSPO_RS13235 1a11ae46ce0726e4d5db4278cd484b69 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 87 99 - T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13235 1a11ae46ce0726e4d5db4278cd484b69 169 Gene3D G3DSA:2.70.70.10 17 168 2.8E-57 T 09-11-2016 CLOSPO_RS13235 1a11ae46ce0726e4d5db4278cd484b69 169 SUPERFAMILY SSF51261 22 166 6.98E-54 T 09-11-2016 IPR011055 Duplicated hybrid motif CLOSPO_RS13235 1a11ae46ce0726e4d5db4278cd484b69 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 26 144 2.1E-47 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13235 1a11ae46ce0726e4d5db4278cd484b69 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 25 145 6.4E-51 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 4.1E-19 T 09-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 105 117 4.1E-19 T 09-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 4.1E-19 T 09-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 4.1E-19 T 09-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 5 157 2.3E-48 T 09-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 PANTHER PTHR11071 15 150 2.5E-54 T 09-11-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 PIRSF PIRSF001467 3 162 4.0E-40 T 09-11-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 SUPERFAMILY SSF50891 4 158 5.11E-53 T 09-11-2016 IPR029000 Cyclophilin-like domain CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 Gene3D G3DSA:2.40.100.10 2 159 2.9E-57 T 09-11-2016 IPR029000 Cyclophilin-like domain CLOSPO_RS15055 a43b1bf83fbff9ee92d31bc1df22ff3a 172 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 09-11-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CLOSPO_RS08765 a41e744bc69042aaab506ecbe3de8690 196 SUPERFAMILY SSF51004 6 189 1.05E-28 T 09-11-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CLOSPO_RS08765 a41e744bc69042aaab506ecbe3de8690 196 Gene3D G3DSA:2.130.10.10 5 194 3.5E-26 T 09-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CLOSPO_RS08765 a41e744bc69042aaab506ecbe3de8690 196 PANTHER PTHR13833 6 189 6.1E-24 T 09-11-2016 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 SUPERFAMILY SSF53681 111 255 1.37E-22 T 09-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 PANTHER PTHR21198:SF3 1 256 1.0E-134 T 09-11-2016 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 Gene3D G3DSA:3.40.50.1860 5 172 3.2E-49 T 09-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 PANTHER PTHR21198 1 256 1.0E-134 T 09-11-2016 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 SUPERFAMILY SSF53681 7 107 4.25E-35 T 09-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 206 9.8E-26 T 09-11-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 243 7.1E-68 T 09-11-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 Hamap MF_00258 Glutamate racemase [murI]. 6 257 32.775 T 09-11-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 09-11-2016 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15050 768c53e82ab5e1cd8685a593139f95f9 257 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 09-11-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 619 665 3.3E-12 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 363 415 1.9E-18 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 864 912 2.8E-10 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 496 531 3.3E-7 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 741 788 2.0E-13 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 Pfam PF01345 Domain of unknown function DUF11 478 530 4.6E-9 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 Pfam PF01345 Domain of unknown function DUF11 591 658 2.7E-13 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 Pfam PF01345 Domain of unknown function DUF11 835 905 1.9E-11 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 Pfam PF01345 Domain of unknown function DUF11 350 409 1.8E-12 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 Pfam PF01345 Domain of unknown function DUF11 715 781 3.2E-13 T 09-11-2016 IPR001434 Domain of unknown function DUF11 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 SUPERFAMILY SSF117074 2 76 4.58E-12 T 09-11-2016 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 Gene3D G3DSA:2.60.40.10 8 64 5.8E-9 T 09-11-2016 IPR013783 Immunoglobulin-like fold CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 PANTHER PTHR34819 3 974 4.0E-150 T 09-11-2016 CLOSPO_RS18805 968812ab308c8ab7ed942004395a1d9a 976 PANTHER PTHR34819:SF3 3 974 4.0E-150 T 09-11-2016 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PANTHER PTHR11732:SF210 4 270 3.9E-142 T 09-11-2016 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 Pfam PF00248 Aldo/keto reductase family 19 260 1.0E-53 T 09-11-2016 IPR023210 NADP-dependent oxidoreductase domain CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 09-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 09-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 SUPERFAMILY SSF51430 6 266 1.17E-92 T 09-11-2016 IPR023210 NADP-dependent oxidoreductase domain CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PANTHER PTHR11732 4 270 3.9E-142 T 09-11-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 Gene3D G3DSA:3.20.20.100 7 270 9.8E-101 T 09-11-2016 IPR023210 NADP-dependent oxidoreductase domain CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 09-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PRINTS PR00069 Aldo-keto reductase signature 158 187 8.1E-49 T 09-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PRINTS PR00069 Aldo-keto reductase signature 195 219 8.1E-49 T 09-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PRINTS PR00069 Aldo-keto reductase signature 39 63 8.1E-49 T 09-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PRINTS PR00069 Aldo-keto reductase signature 124 141 8.1E-49 T 09-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOSPO_RS18330 de13b629569b898865024166f4eef17a 280 PRINTS PR00069 Aldo-keto reductase signature 95 113 8.1E-49 T 09-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOSPO_RS16635 a8dee2e2226ad7c29a8a18fdd2191a01 247 PANTHER PTHR34385:SF1 1 244 8.4E-75 T 09-11-2016 CLOSPO_RS16635 a8dee2e2226ad7c29a8a18fdd2191a01 247 SUPERFAMILY SSF55166 84 235 4.97E-37 T 09-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain CLOSPO_RS16635 a8dee2e2226ad7c29a8a18fdd2191a01 247 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 101 227 5.6E-43 T 09-11-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CLOSPO_RS16635 a8dee2e2226ad7c29a8a18fdd2191a01 247 PANTHER PTHR34385 1 244 8.4E-75 T 09-11-2016 CLOSPO_RS13115 7340fdd6d34ac6b2077dae6fcba9f3a2 372 PANTHER PTHR30472:SF32 16 370 7.8E-174 T 09-11-2016 CLOSPO_RS13115 7340fdd6d34ac6b2077dae6fcba9f3a2 372 Gene3D G3DSA:1.10.3470.10 27 366 2.6E-106 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS13115 7340fdd6d34ac6b2077dae6fcba9f3a2 372 SUPERFAMILY SSF81345 23 364 1.7E-80 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS13115 7340fdd6d34ac6b2077dae6fcba9f3a2 372 Pfam PF01032 FecCD transport family 37 364 6.6E-94 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS13115 7340fdd6d34ac6b2077dae6fcba9f3a2 372 PANTHER PTHR30472 16 370 7.8E-174 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS16380 5faf5a6a55fccfd50d2b1b5ed5d769fc 130 PANTHER PTHR10245 1 126 4.5E-18 T 09-11-2016 CLOSPO_RS16380 5faf5a6a55fccfd50d2b1b5ed5d769fc 130 Pfam PF01381 Helix-turn-helix 7 61 2.6E-17 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16380 5faf5a6a55fccfd50d2b1b5ed5d769fc 130 SMART SM00530 6 61 1.3E-16 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16380 5faf5a6a55fccfd50d2b1b5ed5d769fc 130 PANTHER PTHR10245:SF47 1 126 4.5E-18 T 09-11-2016 CLOSPO_RS16380 5faf5a6a55fccfd50d2b1b5ed5d769fc 130 Gene3D G3DSA:1.10.260.40 1 62 1.0E-24 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16380 5faf5a6a55fccfd50d2b1b5ed5d769fc 130 SUPERFAMILY SSF47413 1 65 5.9E-18 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 1700 1847 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 608 709 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 1482 1495 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 934 1000 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 1217 1304 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 608 709 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 222 434 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 934 1000 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF13306 Leucine rich repeats (6 copies) 1717 1843 9.2E-21 T 09-11-2016 IPR026906 Leucine rich repeat 5 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF13306 Leucine rich repeats (6 copies) 1243 1352 1.2E-23 T 09-11-2016 IPR026906 Leucine rich repeat 5 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF13306 Leucine rich repeats (6 copies) 850 972 1.4E-28 T 09-11-2016 IPR026906 Leucine rich repeat 5 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF13306 Leucine rich repeats (6 copies) 605 725 6.6E-31 T 09-11-2016 IPR026906 Leucine rich repeat 5 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 1700 1847 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017:SF153 1326 1462 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 SUPERFAMILY SSF52058 1263 1449 6.38E-5 T 09-11-2016 IPR032675 Leucine-rich repeat domain, L domain-like CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 1326 1462 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 1482 1495 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Gene3D G3DSA:3.80.10.10 1261 1448 8.2E-6 T 09-11-2016 IPR032675 Leucine-rich repeat domain, L domain-like CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF04122 Putative cell wall binding repeat 2 239 329 1.1E-13 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF04122 Putative cell wall binding repeat 2 137 227 1.2E-13 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 Pfam PF04122 Putative cell wall binding repeat 2 39 123 2.1E-18 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 1217 1304 0.0 T 09-11-2016 CLOSPO_RS12765 a74d0087ae4eebe12f6981fcbcd39365 1876 PANTHER PTHR11017 222 434 0.0 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 Pfam PF00271 Helicase conserved C-terminal domain 689 824 2.6E-15 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799 221 429 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 Gene3D G3DSA:3.40.50.300 244 419 4.3E-20 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799 751 854 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 Pfam PF00176 SNF2 family N-terminal domain 246 423 5.9E-11 T 09-11-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799:SF712 446 468 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799:SF712 221 429 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799:SF712 68 114 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799:SF712 751 854 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799:SF712 637 722 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799:SF712 535 564 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 Gene3D G3DSA:3.40.50.300 675 847 1.1E-24 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799 446 468 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799 637 722 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799 68 114 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 PANTHER PTHR10799 535 564 2.2E-147 T 09-11-2016 CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 SUPERFAMILY SSF52540 214 424 6.32E-28 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 SMART SM00490 720 824 4.3E-11 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 SUPERFAMILY SSF52540 672 723 3.22E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 SUPERFAMILY SSF52540 353 420 3.22E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 SUPERFAMILY SSF52540 752 859 3.22E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16705 79e39fdbef4c8acf10aba40b6e722d46 1084 SMART SM00487 245 435 2.1E-11 T 09-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 Gene3D G3DSA:1.20.1250.20 16 197 4.3E-31 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 428 2.5E-90 T 09-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 Pfam PF07690 Major Facilitator Superfamily 25 413 6.2E-59 T 09-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 SUPERFAMILY SSF103473 252 472 5.62E-74 T 09-11-2016 IPR020846 Major facilitator superfamily domain CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 SUPERFAMILY SSF103473 9 200 5.62E-74 T 09-11-2016 IPR020846 Major facilitator superfamily domain CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 PANTHER PTHR23501:SF5 5 468 1.3E-163 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 PANTHER PTHR23501 5 468 1.3E-163 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 1.8E-10 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 341 361 1.8E-10 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 1.8E-10 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 1.8E-10 T 09-11-2016 CLOSPO_RS16595 0155eadad3e8f74cdd5f761c62916e3f 477 Gene3D G3DSA:1.20.1250.20 262 470 3.8E-27 T 09-11-2016 CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 Pfam PF00436 Single-strand binding protein family 1 102 1.2E-35 T 09-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 PANTHER PTHR10302 1 137 2.2E-43 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 PIRSF PIRSF002070 1 147 6.4E-38 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 Hamap MF_00984 Single-stranded DNA-binding protein. 1 106 34.367 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 125 1.0E-36 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 SUPERFAMILY SSF50249 1 148 1.75E-47 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14660 9d7bdfdff19850ce98fcd0e9a4d01613 148 Gene3D G3DSA:2.40.50.140 1 138 6.9E-42 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS17385 ffc070bd04f6a9d9a7a49a937ea56df8 151 Gene3D G3DSA:3.20.80.10 1 150 1.1E-38 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17385 ffc070bd04f6a9d9a7a49a937ea56df8 151 SMART SM00871 1 151 3.4E-26 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS17385 ffc070bd04f6a9d9a7a49a937ea56df8 151 SUPERFAMILY SSF55136 1 150 2.09E-27 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17385 ffc070bd04f6a9d9a7a49a937ea56df8 151 Pfam PF06445 GyrI-like small molecule binding domain 1 150 6.6E-27 T 09-11-2016 IPR029442 GyrI-like small molecule binding domain CLOSPO_RS17385 ffc070bd04f6a9d9a7a49a937ea56df8 151 PANTHER PTHR40055 1 134 8.1E-14 T 09-11-2016 CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 PANTHER PTHR23131:SF4 12 128 1.6E-112 T 09-11-2016 CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 SUPERFAMILY SSF56281 21 324 3.8E-53 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 SMART SM00849 22 231 1.4E-24 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 Pfam PF00753 Metallo-beta-lactamase superfamily 24 231 2.9E-13 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 PANTHER PTHR23131 146 325 1.6E-112 T 09-11-2016 CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 PANTHER PTHR23131 12 128 1.6E-112 T 09-11-2016 CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 PANTHER PTHR23131:SF4 146 325 1.6E-112 T 09-11-2016 CLOSPO_RS16795 27c4c655b2517270f1b60ac8089b71ae 328 Gene3D G3DSA:3.60.15.10 9 258 1.0E-39 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946 7 205 0.0 T 09-11-2016 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 SUPERFAMILY SSF52374 7 224 3.38E-139 T 09-11-2016 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 SUPERFAMILY SSF52374 409 619 3.38E-139 T 09-11-2016 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Gene3D G3DSA:3.40.50.620 415 595 1.1E-142 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Gene3D G3DSA:3.40.50.620 6 220 1.1E-142 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 813 0.0 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946 286 449 0.0 T 09-11-2016 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946 238 263 0.0 T 09-11-2016 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946 465 812 0.0 T 09-11-2016 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946:SF7 238 263 0.0 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 397 1.3E-66 T 09-11-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Pfam PF09334 tRNA synthetases class I (M) 40 180 2.5E-17 T 09-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 553 563 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 520 542 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 481 499 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 7.4E-50 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 410 605 3.1E-20 T 09-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Gene3D G3DSA:3.90.740.10 221 414 1.5E-57 T 09-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Gene3D G3DSA:1.10.730.10 596 748 1.2E-34 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946:SF7 286 449 0.0 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 SUPERFAMILY SSF47323 621 812 2.29E-33 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 SUPERFAMILY SSF50677 224 408 4.6E-54 T 09-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946:SF7 7 205 0.0 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Pfam PF08264 Anticodon-binding domain of tRNA 658 776 1.8E-22 T 09-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 PANTHER PTHR11946:SF7 465 812 0.0 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS13780 c6760f1bf003aaeec6bc5427ad35afe2 813 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 812 21.775 T 09-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 CLOSPO_RS17350 de52d41beb334929ac05da2be2532066 213 PANTHER PTHR36179 1 213 7.0E-113 T 09-11-2016 CLOSPO_RS17350 de52d41beb334929ac05da2be2532066 213 SUPERFAMILY SSF100950 13 153 4.81E-5 T 09-11-2016 CLOSPO_RS17350 de52d41beb334929ac05da2be2532066 213 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 14 207 9.0E-61 T 09-11-2016 IPR003741 LUD domain CLOSPO_RS17350 de52d41beb334929ac05da2be2532066 213 Gene3D G3DSA:3.40.50.10420 10 153 2.5E-8 T 09-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CLOSPO_RS17350 de52d41beb334929ac05da2be2532066 213 PIRSF PIRSF020269 1 213 1.6E-88 T 09-11-2016 IPR009501 Uncharacterised conserved protein UCP020269 CLOSPO_RS17350 de52d41beb334929ac05da2be2532066 213 PANTHER PTHR36179:SF2 1 213 7.0E-113 T 09-11-2016 CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 81 100 - T 09-11-2016 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 PANTHER PTHR30619:SF1 2 288 4.5E-99 T 09-11-2016 CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 SUPERFAMILY SSF56281 29 270 1.57E-46 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 SMART SM00849 39 231 1.9E-5 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 Pfam PF00753 Metallo-beta-lactamase superfamily 38 105 2.1E-15 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 Gene3D G3DSA:3.60.15.10 19 269 3.0E-31 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16000 770a3e2bc81f034649d1e29230e1cc4e 290 PANTHER PTHR30619 2 288 4.5E-99 T 09-11-2016 CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 Pfam PF00271 Helicase conserved C-terminal domain 233 340 4.1E-27 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 Pfam PF00270 DEAD/DEAH box helicase 25 197 6.1E-52 T 09-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 PANTHER PTHR24031 1 393 2.9E-193 T 09-11-2016 CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 09-11-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 Gene3D G3DSA:3.40.50.300 3 212 6.3E-81 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 Gene3D G3DSA:3.40.50.300 213 374 2.0E-54 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 PANTHER PTHR24031:SF261 1 393 2.9E-193 T 09-11-2016 CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 SMART SM00487 20 223 3.5E-59 T 09-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 SUPERFAMILY SSF52540 76 361 4.87E-76 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16580 8a8b69c12a248281592e119d27156af7 425 SMART SM00490 259 340 4.9E-32 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 SUPERFAMILY SSF53738 86 192 3.92E-20 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 86 189 6.5E-23 T 09-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 Gene3D G3DSA:3.40.120.10 197 298 1.1E-24 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 PANTHER PTHR22573 1 299 7.5E-135 T 09-11-2016 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 Gene3D G3DSA:3.40.120.10 1 93 8.9E-27 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 185 5.6E-8 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 15 29 5.6E-8 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 103 122 5.6E-8 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 16 25 - T 09-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 SUPERFAMILY SSF53738 178 298 1.18E-20 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 Gene3D G3DSA:3.40.120.10 104 188 5.3E-22 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 SUPERFAMILY SSF53738 1 110 1.65E-21 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 PANTHER PTHR22573:SF54 1 299 7.5E-135 T 09-11-2016 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 1 56 3.9E-19 T 09-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS02400 4e19613e60f37b9c29f7072b108eca9d 299 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 198 298 8.0E-16 T 09-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 473 1.0E-15 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 Pfam PF00672 HAMP domain 179 242 4.9E-11 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 312 8.3E-10 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 SMART SM00387 363 475 6.7E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 SUPERFAMILY SSF47384 238 316 4.71E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 SUPERFAMILY SSF55874 323 471 7.2E-33 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 SMART SM00304 194 247 6.4E-12 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 Gene3D G3DSA:3.30.565.10 321 471 1.1E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 SMART SM00388 255 321 4.1E-10 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 PANTHER PTHR24423 188 471 9.3E-57 T 09-11-2016 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 SUPERFAMILY SSF158472 195 246 1.44E-10 T 09-11-2016 CLOSPO_RS16610 abd922fe0145fd4119efb48f416b23ad 475 Gene3D G3DSA:1.10.287.130 246 314 4.9E-12 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 SMART SM00388 356 425 4.4E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 581 2.4E-25 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 216 335 6.5E-9 T 09-11-2016 IPR000014 PAS domain CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 Gene3D G3DSA:3.30.565.10 411 582 6.8E-47 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 Gene3D G3DSA:1.10.287.130 362 410 3.4E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 2.8E-16 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 2.8E-16 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 2.8E-16 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 2.8E-16 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 SUPERFAMILY SSF55785 203 328 1.56E-8 T 09-11-2016 IPR000014 PAS domain CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 358 425 1.1E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 PANTHER PTHR24423 201 589 2.2E-92 T 09-11-2016 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 PANTHER PTHR24423 11 20 2.2E-92 T 09-11-2016 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 SUPERFAMILY SSF47384 345 425 6.87E-18 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 Gene3D G3DSA:3.30.450.20 218 361 4.1E-11 T 09-11-2016 CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 SUPERFAMILY SSF55874 414 583 5.24E-45 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS12975 cd72e740c8fba9abe62c2d70e1d01c46 617 SMART SM00387 471 583 1.6E-36 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15630 d8137562c1362d122b8201843a84647c 258 Pfam PF02596 Uncharacterised ArCR, COG2043 10 216 4.4E-49 T 09-11-2016 IPR003748 Protein of unknown function DUF169 CLOSPO_RS15630 d8137562c1362d122b8201843a84647c 258 PANTHER PTHR37954 1 249 2.3E-129 T 09-11-2016 CLOSPO_RS15630 d8137562c1362d122b8201843a84647c 258 PANTHER PTHR37954:SF1 1 249 2.3E-129 T 09-11-2016 CLOSPO_RS15010 8369dfdb1e613246e69151b4a8ec04f1 405 Pfam PF07690 Major Facilitator Superfamily 38 336 4.2E-32 T 09-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOSPO_RS15010 8369dfdb1e613246e69151b4a8ec04f1 405 SUPERFAMILY SSF103473 24 400 2.09E-53 T 09-11-2016 IPR020846 Major facilitator superfamily domain CLOSPO_RS15010 8369dfdb1e613246e69151b4a8ec04f1 405 PANTHER PTHR23501:SF79 3 404 7.9E-204 T 09-11-2016 CLOSPO_RS15010 8369dfdb1e613246e69151b4a8ec04f1 405 PANTHER PTHR23501 3 404 7.9E-204 T 09-11-2016 CLOSPO_RS15010 8369dfdb1e613246e69151b4a8ec04f1 405 Gene3D G3DSA:1.20.1250.20 236 399 1.0E-16 T 09-11-2016 CLOSPO_RS15010 8369dfdb1e613246e69151b4a8ec04f1 405 Gene3D G3DSA:1.20.1250.20 21 201 2.9E-21 T 09-11-2016 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Gene3D G3DSA:3.30.2060.10 142 217 1.8E-15 T 09-11-2016 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 PANTHER PTHR14025 409 1122 0.0 T 09-11-2016 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1098 0.0 T 09-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Pfam PF00270 DEAD/DEAH box helicase 626 785 5.4E-19 T 09-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SUPERFAMILY SSF52540 16 366 2.9E-88 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SMART SM01058 500 597 2.4E-49 T 09-11-2016 IPR003711 CarD-like/TRCF domain CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SMART SM00487 621 811 4.4E-39 T 09-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SUPERFAMILY SSF52540 544 804 1.98E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SUPERFAMILY SSF52540 379 488 8.85E-14 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1121 29.364 T 09-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Pfam PF00271 Helicase conserved C-terminal domain 827 930 1.1E-19 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SUPERFAMILY SSF141259 494 569 1.03E-24 T 09-11-2016 IPR003711 CarD-like/TRCF domain CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SUPERFAMILY SSF52540 803 1010 1.74E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Pfam PF03461 TRCF domain 1025 1115 1.3E-26 T 09-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 PANTHER PTHR14025:SF21 409 1122 0.0 T 09-11-2016 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Pfam PF02559 CarD-like/TRCF domain 501 596 1.5E-31 T 09-11-2016 IPR003711 CarD-like/TRCF domain CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SMART SM00490 847 931 3.7E-20 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Gene3D G3DSA:3.40.50.300 820 977 2.8E-36 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 Gene3D G3DSA:3.40.50.300 610 807 5.3E-59 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SUPERFAMILY SSF143517 1011 1165 1.96E-34 T 09-11-2016 CLOSPO_RS15170 416bee19883e772839f3eb54acfaada2 1168 SMART SM00982 1024 1123 1.6E-34 T 09-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 PANTHER PTHR30478 2 366 1.1E-135 T 09-11-2016 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 243 363 5.8E-30 T 09-11-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 SUPERFAMILY SSF55979 1 117 3.34E-27 T 09-11-2016 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 SUPERFAMILY SSF55979 123 242 4.45E-27 T 09-11-2016 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 PIRSF PIRSF000804 1 365 2.2E-114 T 09-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 364 4.2E-96 T 09-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 3.4E-30 T 09-11-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 Gene3D G3DSA:3.10.150.10 247 365 4.3E-36 T 09-11-2016 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 SMART SM00480 17 360 1.0E-114 T 09-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 SUPERFAMILY SSF55979 244 364 2.09E-34 T 09-11-2016 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 239 6.6E-29 T 09-11-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 Gene3D G3DSA:3.10.150.10 122 246 4.0E-36 T 09-11-2016 CLOSPO_RS14540 bb0e904e8268882d9415e95078708bb8 367 Gene3D G3DSA:3.10.150.10 1 119 9.7E-28 T 09-11-2016 CLOSPO_RS17030 232d6395402a397dc57f63163dea95db 91 PANTHER PTHR37812:SF1 1 90 3.3E-23 T 09-11-2016 CLOSPO_RS17030 232d6395402a397dc57f63163dea95db 91 SUPERFAMILY SSF46689 1 89 1.52E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17030 232d6395402a397dc57f63163dea95db 91 Gene3D G3DSA:1.10.10.60 50 88 3.2E-6 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17030 232d6395402a397dc57f63163dea95db 91 PANTHER PTHR37812 1 90 3.3E-23 T 09-11-2016 CLOSPO_RS16935 cf5272d93ca17b314c9cbe9b5c834d1f 202 Gene3D G3DSA:3.20.80.10 1 199 8.2E-78 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS16935 cf5272d93ca17b314c9cbe9b5c834d1f 202 SUPERFAMILY SSF55136 114 191 2.62E-9 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS16935 cf5272d93ca17b314c9cbe9b5c834d1f 202 PIRSF PIRSF031644 1 201 5.8E-76 T 09-11-2016 IPR008319 Uncharacterised conserved protein UCP031644 CLOSPO_RS16935 cf5272d93ca17b314c9cbe9b5c834d1f 202 Pfam PF06445 GyrI-like small molecule binding domain 18 197 7.0E-26 T 09-11-2016 IPR029442 GyrI-like small molecule binding domain CLOSPO_RS17935 c39ea1a9b2ca4def08f6434082e70b55 181 Gene3D G3DSA:3.40.630.30 14 180 9.8E-39 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17935 c39ea1a9b2ca4def08f6434082e70b55 181 Pfam PF00583 Acetyltransferase (GNAT) family 76 155 1.9E-16 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS17935 c39ea1a9b2ca4def08f6434082e70b55 181 PANTHER PTHR23091:SF66 4 181 1.2E-27 T 09-11-2016 CLOSPO_RS17935 c39ea1a9b2ca4def08f6434082e70b55 181 PANTHER PTHR23091 4 181 1.2E-27 T 09-11-2016 CLOSPO_RS17935 c39ea1a9b2ca4def08f6434082e70b55 181 SUPERFAMILY SSF55729 11 181 9.81E-33 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13925 c39e0c58f0c60f0c0db478a2fe7dfdd7 358 Pfam PF08486 Stage II sporulation protein 81 185 1.9E-27 T 09-11-2016 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CLOSPO_RS13925 c39e0c58f0c60f0c0db478a2fe7dfdd7 358 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 13 352 9.6E-115 T 09-11-2016 IPR014225 Sporulation stage II, protein D firmicutes CLOSPO_RS13925 c39e0c58f0c60f0c0db478a2fe7dfdd7 358 PANTHER PTHR30032:SF4 66 357 1.8E-70 T 09-11-2016 CLOSPO_RS13925 c39e0c58f0c60f0c0db478a2fe7dfdd7 358 PANTHER PTHR30032 66 357 1.8E-70 T 09-11-2016 CLOSPO_RS13925 c39e0c58f0c60f0c0db478a2fe7dfdd7 358 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 82 352 4.0E-79 T 09-11-2016 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CLOSPO_RS15820 cdd42d81b80dceab9f6979b381ca23d1 378 PANTHER PTHR30294 1 378 2.8E-55 T 09-11-2016 CLOSPO_RS15820 cdd42d81b80dceab9f6979b381ca23d1 378 Pfam PF12698 ABC-2 family transporter protein 19 367 2.0E-20 T 09-11-2016 CLOSPO_RS15820 cdd42d81b80dceab9f6979b381ca23d1 378 PANTHER PTHR30294:SF23 1 378 2.8E-55 T 09-11-2016 CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 PANTHER PTHR11935 118 244 1.6E-71 T 09-11-2016 CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 PANTHER PTHR11935 11 99 1.6E-71 T 09-11-2016 CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 SMART SM00849 21 219 5.2E-9 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 Gene3D G3DSA:3.60.15.10 135 236 4.6E-32 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 Gene3D G3DSA:3.60.15.10 1 97 4.6E-32 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 PANTHER PTHR11935:SF95 11 99 1.6E-71 T 09-11-2016 CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 SUPERFAMILY SSF56281 1 238 6.03E-33 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 PANTHER PTHR11935:SF95 118 244 1.6E-71 T 09-11-2016 CLOSPO_RS13365 f01c17acfc0afa6c23757403db4786b1 244 Pfam PF00753 Metallo-beta-lactamase superfamily 24 186 1.0E-13 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18915 6e1ff6224a85c83fd2f47e6d2008fa41 131 SUPERFAMILY SSF141371 46 127 5.89E-6 T 09-11-2016 CLOSPO_RS18915 6e1ff6224a85c83fd2f47e6d2008fa41 131 Gene3D G3DSA:2.40.10.220 47 130 7.8E-8 T 09-11-2016 CLOSPO_RS18915 6e1ff6224a85c83fd2f47e6d2008fa41 131 Pfam PF07238 PilZ domain 20 128 7.0E-13 T 09-11-2016 IPR009875 PilZ domain GO:0035438 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.6E-14 T 09-11-2016 IPR007159 SpoVT-AbrB domain GO:0003677 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 Gene3D G3DSA:2.10.260.10 1 52 3.3E-28 T 09-11-2016 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 SUPERFAMILY SSF55781 101 178 1.92E-7 T 09-11-2016 IPR029016 GAF domain-like CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 SMART SM00966 8 52 1.6E-9 T 09-11-2016 IPR007159 SpoVT-AbrB domain GO:0003677 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 PANTHER PTHR36432:SF1 2 178 1.2E-114 T 09-11-2016 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 PIRSF PIRSF026579 1 183 7.8E-90 T 09-11-2016 IPR014213 Sporulation stage V, protein T CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 182 8.5E-90 T 09-11-2016 IPR014213 Sporulation stage V, protein T CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 SUPERFAMILY SSF89447 1 51 3.66E-14 T 09-11-2016 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 182 3.9E-47 T 09-11-2016 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 Gene3D G3DSA:3.30.450.40 102 178 2.6E-6 T 09-11-2016 IPR029016 GAF domain-like CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 PANTHER PTHR36432 2 178 1.2E-114 T 09-11-2016 CLOSPO_RS15180 0fd93ac2d1e026a6c55665518561b35e 183 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 9.2E-10 T 09-11-2016 IPR007159 SpoVT-AbrB domain GO:0003677 CLOSPO_RS13540 b1399619dabe8d55659e4a6614b0b667 252 PANTHER PTHR30457 1 252 8.9E-91 T 09-11-2016 CLOSPO_RS13540 b1399619dabe8d55659e4a6614b0b667 252 Pfam PF01975 Survival protein SurE 3 188 5.1E-57 T 09-11-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CLOSPO_RS13540 b1399619dabe8d55659e4a6614b0b667 252 SUPERFAMILY SSF64167 1 250 4.19E-73 T 09-11-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CLOSPO_RS13540 b1399619dabe8d55659e4a6614b0b667 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 238 2.5E-65 T 09-11-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CLOSPO_RS13540 b1399619dabe8d55659e4a6614b0b667 252 Gene3D G3DSA:3.40.1210.10 1 250 1.1E-80 T 09-11-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CLOSPO_RS13540 b1399619dabe8d55659e4a6614b0b667 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 252 31.899 T 09-11-2016 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 SMART SM00382 28 220 2.5E-13 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 PANTHER PTHR24220 5 245 9.7E-99 T 09-11-2016 CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 Gene3D G3DSA:3.40.50.300 3 243 2.3E-69 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 SUPERFAMILY SSF52540 4 234 1.86E-61 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 PANTHER PTHR24220:SF585 5 245 9.7E-99 T 09-11-2016 CLOSPO_RS12720 81a3e8af02f7b8eaf411cf203592683e 248 Pfam PF00005 ABC transporter 19 172 7.3E-34 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18460 d9361d6c63b15fd9dcd0fa0ae53df7f0 424 PANTHER PTHR33171:SF3 1 408 2.5E-177 T 09-11-2016 CLOSPO_RS18460 d9361d6c63b15fd9dcd0fa0ae53df7f0 424 PANTHER PTHR33171 1 408 2.5E-177 T 09-11-2016 CLOSPO_RS18460 d9361d6c63b15fd9dcd0fa0ae53df7f0 424 Pfam PF09861 Domain of unknown function (DUF2088) 8 213 2.4E-77 T 09-11-2016 IPR018657 Domain of unknown function DUF2088 CLOSPO_RS16155 48aee2e44bcdab756d174809f5e754e1 319 PANTHER PTHR30193:SF10 15 319 1.5E-154 T 09-11-2016 CLOSPO_RS16155 48aee2e44bcdab756d174809f5e754e1 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 304 3.6E-17 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16155 48aee2e44bcdab756d174809f5e754e1 319 PANTHER PTHR30193 15 319 1.5E-154 T 09-11-2016 CLOSPO_RS16155 48aee2e44bcdab756d174809f5e754e1 319 SUPERFAMILY SSF161098 44 307 4.58E-56 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16155 48aee2e44bcdab756d174809f5e754e1 319 Gene3D G3DSA:1.10.3720.10 46 305 6.7E-52 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS17670 59f37314f8324ae208636d5b2ca51573 102 Pfam PF01638 HxlR-like helix-turn-helix 16 101 2.6E-32 T 09-11-2016 IPR002577 Helix-turn-helix, HxlR type CLOSPO_RS17670 59f37314f8324ae208636d5b2ca51573 102 SUPERFAMILY SSF46785 4 101 1.14E-27 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17670 59f37314f8324ae208636d5b2ca51573 102 PANTHER PTHR33204 2 101 2.9E-49 T 09-11-2016 CLOSPO_RS17670 59f37314f8324ae208636d5b2ca51573 102 PANTHER PTHR33204:SF13 2 101 2.9E-49 T 09-11-2016 CLOSPO_RS17670 59f37314f8324ae208636d5b2ca51573 102 Gene3D G3DSA:1.10.10.10 4 101 4.0E-34 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 SMART SM00382 373 560 1.0E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 SUPERFAMILY SSF90123 25 333 3.4E-62 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 Pfam PF00005 ABC transporter 364 514 1.7E-31 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 SUPERFAMILY SSF52540 343 584 7.59E-85 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 PANTHER PTHR24221 12 585 2.8E-205 T 09-11-2016 CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 Gene3D G3DSA:1.20.1560.10 25 334 2.5E-62 T 09-11-2016 CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 Pfam PF00664 ABC transporter transmembrane region 37 304 7.5E-36 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17235 d3cb8d836d074f6e81c20ff862a3d8c3 594 Gene3D G3DSA:3.40.50.300 348 579 1.7E-76 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 195 299 2.4E-12 T 09-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 SUPERFAMILY SSF51735 143 279 1.42E-9 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 SUPERFAMILY SSF52283 1 180 2.64E-28 T 09-11-2016 CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 Gene3D G3DSA:3.40.50.1770 1 181 5.9E-28 T 09-11-2016 CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 SMART SM01003 4 111 4.8E-8 T 09-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 PANTHER PTHR10160 1 93 5.3E-28 T 09-11-2016 CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 Gene3D G3DSA:3.40.50.720 198 280 3.2E-13 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 10 95 7.9E-17 T 09-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CLOSPO_RS15925 d3db8dc037bd7d3cbc4258ce688e4385 317 SMART SM01002 147 273 3.4E-7 T 09-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CLOSPO_RS12730 d2dad231656b552112811b38cafe8672 290 PANTHER PTHR30425 2 290 6.8E-106 T 09-11-2016 CLOSPO_RS12730 d2dad231656b552112811b38cafe8672 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 287 6.4E-18 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS12730 d2dad231656b552112811b38cafe8672 290 SUPERFAMILY SSF161098 10 284 4.49E-31 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS12730 d2dad231656b552112811b38cafe8672 290 PANTHER PTHR30425:SF3 2 290 6.8E-106 T 09-11-2016 CLOSPO_RS12730 d2dad231656b552112811b38cafe8672 290 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 10 287 4.5E-75 T 09-11-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CLOSPO_RS12730 d2dad231656b552112811b38cafe8672 290 Gene3D G3DSA:1.10.3720.10 66 288 1.4E-31 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 SMART SM00382 199 378 6.3E-13 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 Gene3D G3DSA:3.30.230.10 464 639 7.8E-50 T 09-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 Gene3D G3DSA:3.40.50.300 174 365 4.2E-36 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 SUPERFAMILY SSF52540 346 439 1.79E-44 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 SUPERFAMILY SSF52540 164 315 1.79E-44 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 598 616 6.8E-32 T 09-11-2016 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 470 486 6.8E-32 T 09-11-2016 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 207 226 6.8E-32 T 09-11-2016 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 545 564 6.8E-32 T 09-11-2016 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 575 594 6.8E-32 T 09-11-2016 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 442 637 1.2E-34 T 09-11-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 548 556 - T 09-11-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PANTHER PTHR10046 7 639 6.9E-159 T 09-11-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 PANTHER PTHR10046:SF53 7 639 6.9E-159 T 09-11-2016 IPR033141 LonB/LonC peptidase CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 Gene3D G3DSA:1.10.8.60 366 423 3.8E-4 T 09-11-2016 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 TIGRFAM TIGR02903 spore_lon_C: ATP-dependent protease, Lon family 28 639 0.0 T 09-11-2016 IPR014252 Sporulation protease LonC CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 375 1.1E-15 T 09-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 CLOSPO_RS14690 29b3b86f851e12456c5063af184f0022 639 SUPERFAMILY SSF54211 470 638 1.14E-43 T 09-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold CLOSPO_RS13255 61c4b902405bef910825f4b3289ef2d6 656 Pfam PF02687 FtsX-like permease family 67 183 1.9E-11 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS13255 61c4b902405bef910825f4b3289ef2d6 656 PANTHER PTHR30489:SF14 1 643 1.9E-106 T 09-11-2016 CLOSPO_RS13255 61c4b902405bef910825f4b3289ef2d6 656 PANTHER PTHR30489 1 643 1.9E-106 T 09-11-2016 CLOSPO_RS13255 61c4b902405bef910825f4b3289ef2d6 656 PIRSF PIRSF018968 1 655 3.1E-106 T 09-11-2016 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CLOSPO_RS17780 d687425355972e689548cfea9590a858 187 SUPERFAMILY SSF46689 6 69 5.08E-10 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17780 d687425355972e689548cfea9590a858 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 55 2.0E-5 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS17780 d687425355972e689548cfea9590a858 187 Gene3D G3DSA:1.10.10.60 3 39 3.5E-6 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17780 d687425355972e689548cfea9590a858 187 Gene3D G3DSA:1.10.357.10 40 151 4.5E-10 T 09-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CLOSPO_RS16035 38007ac069dce907964d2cf36c5678aa 146 SUPERFAMILY SSF141322 85 144 6.02E-8 T 09-11-2016 CLOSPO_RS16035 38007ac069dce907964d2cf36c5678aa 146 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 143 3.1E-21 T 09-11-2016 IPR002810 NfeD-like, C-terminal domain CLOSPO_RS16035 38007ac069dce907964d2cf36c5678aa 146 Gene3D G3DSA:2.40.50.140 89 143 2.8E-5 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS16035 38007ac069dce907964d2cf36c5678aa 146 PANTHER PTHR33507:SF3 1 145 2.8E-41 T 09-11-2016 CLOSPO_RS16035 38007ac069dce907964d2cf36c5678aa 146 PANTHER PTHR33507 1 145 2.8E-41 T 09-11-2016 CLOSPO_RS15615 abb52a2e33efa147d2bb977621a0b187 314 PANTHER PTHR30482 1 308 5.4E-137 T 09-11-2016 CLOSPO_RS15615 abb52a2e33efa147d2bb977621a0b187 314 PANTHER PTHR30482:SF10 1 308 5.4E-137 T 09-11-2016 CLOSPO_RS15615 abb52a2e33efa147d2bb977621a0b187 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 293 3.0E-48 T 09-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 PANTHER PTHR21091:SF16 1 233 2.2E-72 T 09-11-2016 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 09-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 Pfam PF02602 Uroporphyrinogen-III synthase HemD 263 479 6.2E-51 T 09-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 09-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 SUPERFAMILY SSF53790 1 251 2.36E-70 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 211 5.8E-40 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 SUPERFAMILY SSF69618 249 484 6.28E-50 T 09-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 PANTHER PTHR21091 1 233 2.2E-72 T 09-11-2016 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 236 2.9E-91 T 09-11-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 Gene3D G3DSA:3.40.50.10090 373 484 4.9E-19 T 09-11-2016 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 Gene3D G3DSA:3.40.50.10090 255 372 1.7E-25 T 09-11-2016 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 Gene3D G3DSA:3.40.1010.10 2 117 1.1E-37 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS18015 fb79a157c8467518bec08796426ee0c8 486 Gene3D G3DSA:3.30.950.10 118 254 2.7E-46 T 09-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 CLOSPO_RS13990 0033450e1b0f2a2efb0dfc076ccb38fb 344 PANTHER PTHR22926:SF3 1 335 1.7E-109 T 09-11-2016 CLOSPO_RS13990 0033450e1b0f2a2efb0dfc076ccb38fb 344 Pfam PF00953 Glycosyl transferase family 4 76 233 6.1E-44 T 09-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS13990 0033450e1b0f2a2efb0dfc076ccb38fb 344 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 09-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS13990 0033450e1b0f2a2efb0dfc076ccb38fb 344 PANTHER PTHR22926 1 335 1.7E-109 T 09-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS03425 654ae623131e7fd85c845d0300d2c39b 145 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 1 65 1.2E-14 T 09-11-2016 IPR007621 TPM domain CLOSPO_RS03425 654ae623131e7fd85c845d0300d2c39b 145 PANTHER PTHR30373 1 145 1.1E-38 T 09-11-2016 CLOSPO_RS03425 654ae623131e7fd85c845d0300d2c39b 145 PANTHER PTHR30373:SF2 1 145 1.1E-38 T 09-11-2016 CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 PANTHER PTHR19211 4 277 1.7E-177 T 09-11-2016 CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 SUPERFAMILY SSF52540 135 251 5.69E-46 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 SUPERFAMILY SSF52540 7 98 5.69E-46 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 PANTHER PTHR19211:SF65 4 277 1.7E-177 T 09-11-2016 CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 Pfam PF12848 ABC transporter 233 277 1.1E-9 T 09-11-2016 IPR032781 ABC-transporter extension domain CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 SMART SM00382 32 241 2.8E-7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 Gene3D G3DSA:3.40.50.300 6 94 4.9E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 Gene3D G3DSA:3.40.50.300 128 275 4.9E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04705 2a3b67ac6b687888c876db11c5b71463 277 Pfam PF00005 ABC transporter 24 194 4.7E-26 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17025 207debbe3dcbab0d1fcaf33fdc2798ad 207 Pfam PF04892 VanZ like family 47 162 5.3E-26 T 09-11-2016 IPR006976 VanZ-like CLOSPO_RS17025 207debbe3dcbab0d1fcaf33fdc2798ad 207 PANTHER PTHR36834:SF1 1 162 2.8E-22 T 09-11-2016 CLOSPO_RS17025 207debbe3dcbab0d1fcaf33fdc2798ad 207 PANTHER PTHR36834 1 162 2.8E-22 T 09-11-2016 CLOSPO_RS14150 9e3c62edff76337de7ec7ea84d8c14b6 300 Pfam PF05582 YabG peptidase U57 3 295 5.4E-122 T 09-11-2016 IPR008764 Peptidase U57, YabG CLOSPO_RS14150 9e3c62edff76337de7ec7ea84d8c14b6 300 PIRSF PIRSF011575 1 300 4.3E-134 T 09-11-2016 IPR008764 Peptidase U57, YabG CLOSPO_RS14150 9e3c62edff76337de7ec7ea84d8c14b6 300 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 1 288 9.0E-91 T 09-11-2016 IPR008764 Peptidase U57, YabG CLOSPO_RS14150 9e3c62edff76337de7ec7ea84d8c14b6 300 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 3 296 3.6E-127 T 09-11-2016 IPR008764 Peptidase U57, YabG CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 390 8.4E-187 T 09-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 09-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Gene3D G3DSA:3.30.300.10 144 241 5.2E-49 T 09-11-2016 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 SUPERFAMILY SSF55973 119 240 2.2E-53 T 09-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 391 58.467 T 09-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 SUPERFAMILY SSF55973 3 108 6.67E-48 T 09-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Gene3D G3DSA:3.30.300.10 252 390 4.4E-71 T 09-11-2016 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 PIRSF PIRSF000497 1 391 3.0E-177 T 09-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Pfam PF02772 S-adenosylmethionine synthetase, central domain 123 239 3.7E-50 T 09-11-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 SUPERFAMILY SSF55973 241 389 3.49E-69 T 09-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 124 134 - T 09-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 PANTHER PTHR11964 4 386 3.8E-286 T 09-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 99 1.7E-44 T 09-11-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 380 1.1E-70 T 09-11-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 CLOSPO_RS13870 d1d90d41fc5195e8d565a3d787e9bada 391 Gene3D G3DSA:3.30.300.10 10 143 2.3E-47 T 09-11-2016 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 Pfam PF04397 LytTr DNA-binding domain 141 229 3.8E-17 T 09-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 PANTHER PTHR26402 2 118 2.1E-15 T 09-11-2016 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 SUPERFAMILY SSF52172 1 132 1.57E-20 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 Pfam PF00072 Response regulator receiver domain 4 120 9.4E-18 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 SMART SM00448 2 120 1.9E-16 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 Gene3D G3DSA:2.40.50.40 134 198 2.8E-17 T 09-11-2016 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 Gene3D G3DSA:3.40.50.2300 1 126 3.2E-21 T 09-11-2016 CLOSPO_RS18480 f4cefddc9bd1e52cec440ff5b2c0d1ac 238 SMART SM00850 140 232 5.8E-16 T 09-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 SUPERFAMILY SSF53383 25 392 6.25E-85 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 Gene3D G3DSA:3.90.1150.10 249 393 5.4E-31 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 09-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 PANTHER PTHR11751:SF429 11 390 2.7E-139 T 09-11-2016 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 99 119 2.3E-11 T 09-11-2016 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 236 260 2.3E-11 T 09-11-2016 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 167 191 2.3E-11 T 09-11-2016 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 121 142 2.3E-11 T 09-11-2016 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 Pfam PF00155 Aminotransferase class I and II 35 381 7.4E-53 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 PANTHER PTHR11751 11 390 2.7E-139 T 09-11-2016 CLOSPO_RS18510 24c55a40d0915687ac92c95a76d4f220 394 Gene3D G3DSA:3.40.640.10 48 248 5.4E-56 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 Gene3D G3DSA:1.10.287.180 2 74 6.3E-21 T 09-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 PIRSF PIRSF006092 1 154 1.8E-48 T 09-11-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 SUPERFAMILY SSF46557 2 76 5.89E-20 T 09-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 PANTHER PTHR30437 1 154 3.1E-49 T 09-11-2016 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 1.7E-19 T 09-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 SUPERFAMILY SSF54534 79 153 1.27E-15 T 09-11-2016 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 Gene3D G3DSA:3.10.50.30 75 153 7.6E-22 T 09-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 153 7.0E-43 T 09-11-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 Hamap MF_00105 Transcription elongation factor GreA [greA]. 1 154 27.908 T 09-11-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CLOSPO_RS16845 13e518444bb395cd32a6ab23c702c46f 154 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 153 1.1E-19 T 09-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CLOSPO_RS18540 c7356a283acd3df87ec740f158fa1af3 185 SUPERFAMILY SSF52218 52 183 1.49E-19 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS18540 c7356a283acd3df87ec740f158fa1af3 185 Gene3D G3DSA:3.40.50.360 50 160 7.8E-20 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS18540 c7356a283acd3df87ec740f158fa1af3 185 Pfam PF12724 Flavodoxin domain 61 156 5.9E-10 T 09-11-2016 IPR026816 Flavodoxin domain CLOSPO_RS18900 e611ff40b7f8ae74e4f7aa2266d9f019 54 Pfam PF12669 Virus attachment protein p12 family 2 40 5.4E-10 T 09-11-2016 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 Gene3D G3DSA:2.30.40.10 281 374 4.2E-16 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 Pfam PF01979 Amidohydrolase family 80 368 3.9E-19 T 09-11-2016 IPR006680 Amidohydrolase-related GO:0016787 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 Hamap MF_01518 Adenine deaminase [ade]. 28 594 36.516 T 09-11-2016 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 Pfam PF13382 Adenine deaminase C-terminal domain 426 591 9.3E-68 T 09-11-2016 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 PANTHER PTHR11113 14 370 1.2E-237 T 09-11-2016 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 PANTHER PTHR11113 417 589 1.2E-237 T 09-11-2016 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 PANTHER PTHR11113:SF2 417 589 1.2E-237 T 09-11-2016 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 PANTHER PTHR11113:SF2 14 370 1.2E-237 T 09-11-2016 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 TIGRFAM TIGR01178 ade: adenine deaminase 28 595 1.2E-167 T 09-11-2016 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 SUPERFAMILY SSF51338 337 377 8.44E-20 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 SUPERFAMILY SSF51338 19 84 8.44E-20 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 SUPERFAMILY SSF51556 84 334 2.19E-17 T 09-11-2016 IPR032466 Metal-dependent hydrolase CLOSPO_RS13155 f9dceb7fdb1b6364985b2fe101075f1a 599 Gene3D G3DSA:2.30.40.10 16 123 1.8E-21 T 09-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CLOSPO_RS15985 e2cd89a5c3206f12ccffd83131bb76ff 457 PANTHER PTHR11785 2 457 8.3E-205 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS15985 e2cd89a5c3206f12ccffd83131bb76ff 457 PANTHER PTHR11785:SF259 2 457 8.3E-205 T 09-11-2016 CLOSPO_RS15985 e2cd89a5c3206f12ccffd83131bb76ff 457 PIRSF PIRSF006060 1 452 1.3E-71 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS15985 e2cd89a5c3206f12ccffd83131bb76ff 457 Pfam PF13520 Amino acid permease 11 410 5.2E-57 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 PANTHER PTHR24220:SF327 22 260 6.4E-139 T 09-11-2016 CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 Gene3D G3DSA:3.40.50.300 19 257 9.4E-84 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 PANTHER PTHR24220 22 260 6.4E-139 T 09-11-2016 CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 SMART SM00382 45 233 8.5E-17 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 PIRSF PIRSF039085 17 260 6.3E-114 T 09-11-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 Pfam PF00005 ABC transporter 37 185 1.4E-36 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS15445 a7374b767278b61da2e6fa5b9638da3e 260 SUPERFAMILY SSF52540 20 255 4.46E-79 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 Pfam PF02195 ParB-like nuclease domain 29 116 8.2E-24 T 09-11-2016 IPR003115 ParB/Sulfiredoxin CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 Gene3D G3DSA:3.90.1530.10 19 122 1.1E-38 T 09-11-2016 CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 26 202 1.7E-58 T 09-11-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 PANTHER PTHR33375:SF3 7 282 7.5E-150 T 09-11-2016 CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 SMART SM00470 27 116 1.3E-28 T 09-11-2016 IPR003115 ParB/Sulfiredoxin CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 SUPERFAMILY SSF109709 108 217 6.02E-32 T 09-11-2016 CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 SUPERFAMILY SSF110849 27 152 1.15E-30 T 09-11-2016 IPR003115 ParB/Sulfiredoxin CLOSPO_RS14600 f879b8794f75a3f7b1839b1aae574f46 282 PANTHER PTHR33375 7 282 7.5E-150 T 09-11-2016 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 Pfam PF01555 DNA methylase 111 461 3.7E-36 T 09-11-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PANTHER PTHR13370:SF7 158 248 6.0E-14 T 09-11-2016 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PANTHER PTHR13370:SF7 88 120 6.0E-14 T 09-11-2016 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 174 193 8.4E-7 T 09-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 111 123 8.4E-7 T 09-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PANTHER PTHR13370 158 248 6.0E-14 T 09-11-2016 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 Gene3D G3DSA:3.40.50.150 87 256 1.0E-60 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 Gene3D G3DSA:3.40.50.150 357 495 1.0E-60 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PANTHER PTHR13370 88 120 6.0E-14 T 09-11-2016 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 09-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 SUPERFAMILY SSF53335 162 295 2.58E-54 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 SUPERFAMILY SSF53335 78 131 2.58E-54 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 SUPERFAMILY SSF53335 382 488 2.58E-54 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16715 e30789ba351c8728f2a78c7a751292de 652 PIRSF PIRSF015855 1 651 9.1E-173 T 09-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CLOSPO_RS13630 740ab4995ff6b5e7fa9fc0d5a5f94133 450 PANTHER PTHR35788:SF1 5 450 4.5E-166 T 09-11-2016 CLOSPO_RS13630 740ab4995ff6b5e7fa9fc0d5a5f94133 450 Pfam PF07501 G5 domain 382 449 3.9E-15 T 09-11-2016 IPR011098 G5 domain CLOSPO_RS13630 740ab4995ff6b5e7fa9fc0d5a5f94133 450 Pfam PF12229 Putative peptidoglycan binding domain 83 192 1.2E-21 T 09-11-2016 IPR022029 Putative peptidoglycan binding domain CLOSPO_RS13630 740ab4995ff6b5e7fa9fc0d5a5f94133 450 PANTHER PTHR35788 5 450 4.5E-166 T 09-11-2016 CLOSPO_RS13630 740ab4995ff6b5e7fa9fc0d5a5f94133 450 SMART SM01208 373 450 1.1E-19 T 09-11-2016 IPR011098 G5 domain CLOSPO_RS13630 740ab4995ff6b5e7fa9fc0d5a5f94133 450 Pfam PF04294 VanW like protein 236 365 1.6E-50 T 09-11-2016 IPR007391 Vancomycin resistance VanW CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 PANTHER PTHR21012 2 117 9.2E-64 T 09-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 Pfam PF02261 Aspartate decarboxylase 1 114 3.7E-54 T 09-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 SUPERFAMILY SSF50692 1 116 9.94E-50 T 09-11-2016 IPR009010 Aspartate decarboxylase-like domain CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 PANTHER PTHR21012:SF0 2 117 9.2E-64 T 09-11-2016 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 93 1.0E-36 T 09-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 PIRSF PIRSF006246 1 127 2.1E-53 T 09-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 Gene3D G3DSA:2.40.40.20 1 122 5.9E-57 T 09-11-2016 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 3.2E-49 T 09-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 CLOSPO_RS15460 39ae5fec8610e66c074580840920e59c 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 68.959 T 09-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 PANTHER PTHR10617:SF110 1 322 2.0E-157 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 PANTHER PTHR10617:SF110 400 458 2.0E-157 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 Gene3D G3DSA:3.50.50.60 1 93 5.2E-23 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 Gene3D G3DSA:3.50.50.60 126 278 5.2E-23 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 SUPERFAMILY SSF51905 414 458 2.41E-23 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 SUPERFAMILY SSF51905 95 225 2.41E-23 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 SUPERFAMILY SSF51905 1 67 2.41E-23 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.2E-5 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 411 433 4.2E-5 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 Pfam PF03486 HI0933-like protein 4 50 4.4E-5 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 PANTHER PTHR10617 1 322 2.0E-157 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 PANTHER PTHR10617 400 458 2.0E-157 T 09-11-2016 CLOSPO_RS14710 b99ebca70c1acd58ff35bb9d4bf7e0f2 461 Gene3D G3DSA:3.50.50.60 391 455 2.0E-7 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 SUPERFAMILY SSF161098 9 258 5.76E-62 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 Gene3D G3DSA:3.40.190.10 535 578 1.5E-55 T 09-11-2016 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 Gene3D G3DSA:3.40.190.10 292 398 1.5E-55 T 09-11-2016 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 Gene3D G3DSA:1.10.3720.10 9 261 8.0E-68 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 Pfam PF13416 Bacterial extracellular solute-binding protein 309 567 5.2E-32 T 09-11-2016 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 256 1.5E-19 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PANTHER PTHR30222:SF1 254 613 6.6E-234 T 09-11-2016 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 299 315 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 389 405 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 414 428 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 558 584 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 432 451 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 513 532 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 315 336 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 358 371 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 342 356 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 469 488 7.4E-47 T 09-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 Gene3D G3DSA:3.40.190.10 402 534 2.7E-15 T 09-11-2016 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 PANTHER PTHR30222 254 613 6.6E-234 T 09-11-2016 CLOSPO_RS16160 7d09942993102856a3daa571707a228b 614 SUPERFAMILY SSF53850 293 610 3.32E-83 T 09-11-2016 CLOSPO_RS14365 0ff2d529e1829640cff0cb6dfed39457 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 420 9.3E-82 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS14365 0ff2d529e1829640cff0cb6dfed39457 445 PIRSF PIRSF006603 1 445 7.0E-97 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS14365 0ff2d529e1829640cff0cb6dfed39457 445 Pfam PF01554 MatE 17 179 1.1E-27 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS14365 0ff2d529e1829640cff0cb6dfed39457 445 Pfam PF01554 MatE 245 406 2.9E-32 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS14365 0ff2d529e1829640cff0cb6dfed39457 445 PANTHER PTHR11206 5 442 3.2E-101 T 09-11-2016 CLOSPO_RS14365 0ff2d529e1829640cff0cb6dfed39457 445 PANTHER PTHR11206:SF95 5 442 3.2E-101 T 09-11-2016 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 09-11-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 SMART SM00354 2 72 3.2E-37 T 09-11-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 SUPERFAMILY SSF47413 3 60 1.03E-18 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 Gene3D G3DSA:3.40.50.2300 55 173 1.2E-50 T 09-11-2016 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.1E-5 T 09-11-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.1E-5 T 09-11-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 PANTHER PTHR30146:SF4 1 332 2.9E-139 T 09-11-2016 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 Gene3D G3DSA:3.40.50.2300 174 311 1.9E-45 T 09-11-2016 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 PANTHER PTHR30146 1 332 2.9E-139 T 09-11-2016 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.9E-18 T 09-11-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 324 2.8E-32 T 09-11-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 SUPERFAMILY SSF53822 61 331 2.55E-82 T 09-11-2016 IPR028082 Periplasmic binding protein-like I CLOSPO_RS14225 4d6cb5929079650fe810af9792fdc398 332 Gene3D G3DSA:1.10.260.40 4 54 2.2E-26 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Pfam PF04122 Putative cell wall binding repeat 2 136 225 1.2E-19 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Pfam PF04122 Putative cell wall binding repeat 2 36 123 8.1E-18 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Pfam PF04122 Putative cell wall binding repeat 2 234 324 3.1E-19 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 PANTHER PTHR30032:SF1 4 351 9.0E-62 T 09-11-2016 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 SUPERFAMILY SSF63825 396 617 5.49E-10 T 09-11-2016 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Gene3D G3DSA:2.120.10.30 510 613 7.7E-7 T 09-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Gene3D G3DSA:2.120.10.30 338 509 6.1E-8 T 09-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Gene3D G3DSA:3.40.50.720 272 329 2.2E-4 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Gene3D G3DSA:3.40.50.720 92 140 2.2E-4 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 Pfam PF16472 Domain of unknown function (DUF5050) 338 618 4.4E-39 T 09-11-2016 IPR032485 Domain of unknown function DUF5050 CLOSPO_RS17120 76f147b789efde5fc2717d4738791f9f 636 PANTHER PTHR30032 4 351 9.0E-62 T 09-11-2016 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 09-11-2016 IPR004035 Endonuclease III, iron-sulphur binding site CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 Gene3D G3DSA:1.10.1670.10 123 209 4.8E-37 T 09-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 09-11-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 SUPERFAMILY SSF48150 4 209 2.36E-72 T 09-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 PIRSF PIRSF001435 2 212 4.7E-62 T 09-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 Gene3D G3DSA:1.10.340.30 22 122 9.4E-37 T 09-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 1.2E-4 T 09-11-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 Pfam PF00633 Helix-hairpin-helix motif 99 127 3.3E-8 T 09-11-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 TIGRFAM TIGR01083 nth: endonuclease III 5 194 1.2E-83 T 09-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 SMART SM00478 38 185 1.2E-58 T 09-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 PANTHER PTHR10359 13 211 2.1E-83 T 09-11-2016 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 SMART SM00525 186 206 0.0068 T 09-11-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 PANTHER PTHR10359:SF18 13 211 2.1E-83 T 09-11-2016 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 Hamap MF_00942 Endonuclease III [nth]. 1 209 38.965 T 09-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 CLOSPO_RS13660 9a27be67341d09f918bbf898442f8848 213 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 9.9E-21 T 09-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 SUPERFAMILY SSF89623 1 144 7.85E-62 T 09-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 5.2E-61 T 09-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 Pfam PF02502 Ribose/Galactose Isomerase 3 140 2.1E-61 T 09-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 PIRSF PIRSF005384 1 145 2.9E-61 T 09-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 1.2E-60 T 09-11-2016 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 Gene3D G3DSA:3.40.1400.10 1 144 2.5E-68 T 09-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 CLOSPO_RS14005 473cbf615c212d8eee6e251c3f60312a 145 PANTHER PTHR30345 1 145 1.1E-81 T 09-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 SUPERFAMILY SSF51905 1 218 2.16E-48 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 SUPERFAMILY SSF51905 315 406 2.16E-48 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 PANTHER PTHR13847 2 443 3.9E-146 T 09-11-2016 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 Pfam PF04324 BFD-like [2Fe-2S] binding domain 398 452 2.5E-18 T 09-11-2016 IPR007419 BFD-like [2Fe-2S]-binding domain CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 PANTHER PTHR13847:SF150 2 443 3.9E-146 T 09-11-2016 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 Pfam PF01266 FAD dependent oxidoreductase 3 354 1.2E-64 T 09-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 Gene3D G3DSA:3.50.50.60 137 217 2.6E-44 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 Gene3D G3DSA:3.50.50.60 315 371 2.6E-44 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18860 f97d5f5ea25f25ffdd49fdc52ef1fa5d 472 Gene3D G3DSA:3.50.50.60 1 82 2.6E-44 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 09-11-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 PANTHER PTHR30352 1 58 4.7E-129 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 PANTHER PTHR30352 91 277 4.7E-129 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 PIRSF PIRSF000371 1 277 2.1E-73 T 09-11-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 Gene3D G3DSA:3.80.30.10 111 276 3.9E-47 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 SUPERFAMILY SSF54862 43 94 2.89E-12 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 Gene3D G3DSA:3.30.70.20 43 88 1.6E-9 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 PANTHER PTHR30352:SF13 91 277 4.7E-129 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 Pfam PF04055 Radical SAM superfamily 24 216 2.5E-21 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 Pfam PF13353 4Fe-4S single cluster domain 15 180 2.2E-12 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 TIGRFAM TIGR04041 activase_YjjW: glycine radical enzyme activase, YjjW family 4 277 3.5E-119 T 09-11-2016 IPR023912 Putative glycyl-radical enzyme activating enzyme YjjW CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 PANTHER PTHR30352:SF13 1 58 4.7E-129 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 SUPERFAMILY SSF102114 88 262 3.41E-17 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 SUPERFAMILY SSF102114 26 47 3.41E-17 T 09-11-2016 CLOSPO_RS14945 97bd3fbe9b840480ae382ec8975ebc5a 278 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 09-11-2016 IPR020070 Ribosomal protein L9, N-terminal CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 Gene3D G3DSA:3.40.5.10 1 52 3.2E-23 T 09-11-2016 IPR020070 Ribosomal protein L9, N-terminal CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 Gene3D G3DSA:3.10.430.100 61 147 1.1E-28 T 09-11-2016 IPR020069 Ribosomal protein L9, C-terminal CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.1E-42 T 09-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 SUPERFAMILY SSF55658 1 56 1.5E-18 T 09-11-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 4.9E-24 T 09-11-2016 IPR020070 Ribosomal protein L9, N-terminal CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 26.293 T 09-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 SUPERFAMILY SSF55653 57 146 3.66E-24 T 09-11-2016 IPR020069 Ribosomal protein L9, C-terminal CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 PANTHER PTHR21368 1 147 2.1E-47 T 09-11-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14685 825063406fbfc258a40522a5dc98bd88 147 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 145 9.2E-27 T 09-11-2016 IPR020069 Ribosomal protein L9, C-terminal CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 Pfam PF00005 ABC transporter 18 167 9.4E-34 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 SMART SM00382 27 212 1.6E-14 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 Gene3D G3DSA:3.40.50.300 3 232 2.3E-63 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 PANTHER PTHR24220 4 247 3.4E-114 T 09-11-2016 CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 SUPERFAMILY SSF52540 3 225 5.66E-60 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 PANTHER PTHR24220:SF309 4 247 3.4E-114 T 09-11-2016 CLOSPO_RS13110 dbfe3768ecf6b03dacc7c441bd821230 256 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17175 5d520b4f988b5430735e9f4ddf6e8110 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 125 8.7E-14 T 09-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily CLOSPO_RS17175 5d520b4f988b5430735e9f4ddf6e8110 138 Gene3D G3DSA:3.40.50.270 1 126 6.9E-33 T 09-11-2016 CLOSPO_RS17175 5d520b4f988b5430735e9f4ddf6e8110 138 PANTHER PTHR11717:SF18 2 137 5.7E-32 T 09-11-2016 CLOSPO_RS17175 5d520b4f988b5430735e9f4ddf6e8110 138 SUPERFAMILY SSF52788 1 127 2.22E-29 T 09-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily CLOSPO_RS17175 5d520b4f988b5430735e9f4ddf6e8110 138 SMART SM00226 3 128 5.4E-19 T 09-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily CLOSPO_RS17175 5d520b4f988b5430735e9f4ddf6e8110 138 PANTHER PTHR11717 2 137 5.7E-32 T 09-11-2016 CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 SUPERFAMILY SSF53850 64 520 1.36E-101 T 09-11-2016 CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 445 6.5E-77 T 09-11-2016 IPR000914 Solute-binding protein family 5 domain CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 Gene3D G3DSA:3.40.190.10 167 301 9.2E-36 T 09-11-2016 CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 Gene3D G3DSA:3.10.105.10 302 498 6.9E-37 T 09-11-2016 CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 PANTHER PTHR30290 1 528 2.2E-93 T 09-11-2016 CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 Gene3D G3DSA:3.90.76.10 72 166 9.4E-26 T 09-11-2016 CLOSPO_RS16665 20e79913e11aca215657cd7bedaddb33 528 PIRSF PIRSF002741 3 528 9.8E-78 T 09-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CLOSPO_RS16060 f3e8aa7c9d77a25e0ce46858204707fc 78 PANTHER PTHR10245 1 70 8.0E-39 T 09-11-2016 CLOSPO_RS16060 f3e8aa7c9d77a25e0ce46858204707fc 78 Gene3D G3DSA:1.10.260.40 1 64 2.2E-21 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16060 f3e8aa7c9d77a25e0ce46858204707fc 78 SMART SM00530 4 59 6.2E-11 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16060 f3e8aa7c9d77a25e0ce46858204707fc 78 Pfam PF12844 Helix-turn-helix domain 4 62 4.7E-12 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16060 f3e8aa7c9d77a25e0ce46858204707fc 78 PANTHER PTHR10245:SF61 1 70 8.0E-39 T 09-11-2016 CLOSPO_RS16060 f3e8aa7c9d77a25e0ce46858204707fc 78 SUPERFAMILY SSF47413 2 66 5.36E-17 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 PANTHER PTHR26402 2 224 4.2E-114 T 09-11-2016 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 SMART SM00862 148 224 1.2E-25 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 3.0E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 Gene3D G3DSA:3.40.50.2300 2 119 1.7E-35 T 09-11-2016 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 Pfam PF00072 Response regulator receiver domain 4 113 3.4E-26 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 SUPERFAMILY SSF52172 3 118 1.15E-36 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 Gene3D G3DSA:1.10.10.10 129 225 6.1E-34 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 SMART SM00448 2 112 4.9E-38 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 PANTHER PTHR26402:SF614 2 224 4.2E-114 T 09-11-2016 CLOSPO_RS18615 115849a816cbcf025b48b7c89edb8993 228 SUPERFAMILY SSF46894 127 224 3.97E-30 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 PANTHER PTHR30429 2 270 2.8E-144 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 PIRSF PIRSF002854 1 270 1.6E-109 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 SUPERFAMILY SSF53850 36 270 4.45E-87 T 09-11-2016 CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 PANTHER PTHR30429:SF0 2 270 2.8E-144 T 09-11-2016 CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 Gene3D G3DSA:3.40.190.10 34 163 2.3E-59 T 09-11-2016 CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 Pfam PF03180 NLPA lipoprotein 37 269 1.2E-97 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS18940 a5527e6bb7f8d02b103f08c018076c46 270 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 17 267 7.3E-72 T 09-11-2016 IPR004872 Lipoprotein NlpA family CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 SUPERFAMILY SSF52540 1 227 5.55E-53 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 Gene3D G3DSA:3.40.50.300 2 233 1.7E-46 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 PANTHER PTHR21343 1 490 7.9E-224 T 09-11-2016 CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 Gene3D G3DSA:3.40.50.880 247 450 1.1E-28 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 SUPERFAMILY SSF52317 247 432 7.81E-32 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 224 6.7E-28 T 09-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 248 437 4.7E-61 T 09-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 PANTHER PTHR21343:SF1 1 490 7.9E-224 T 09-11-2016 CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 486 3.6E-165 T 09-11-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 CLOSPO_RS17975 dffa8714f2525fbfca88dc2be7ee9076 493 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 493 174.02 T 09-11-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 CLOSPO_RS16385 9dd4857d5e6639734dd775e300c92fd3 367 Pfam PF07532 Bacterial Ig-like domain (group 4) 131 185 1.9E-11 T 09-11-2016 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CLOSPO_RS16385 9dd4857d5e6639734dd775e300c92fd3 367 Gene3D G3DSA:1.25.40.10 45 110 8.9E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16385 9dd4857d5e6639734dd775e300c92fd3 367 SUPERFAMILY SSF48452 49 116 4.47E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 PANTHER PTHR32125 1 154 9.0E-56 T 09-11-2016 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 09-11-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 Gene3D G3DSA:3.30.1330.50 1 154 8.5E-68 T 09-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 SUPERFAMILY SSF69765 1 154 1.83E-64 T 09-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 155 33.914 T 09-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 Pfam PF02542 YgbB family 1 154 3.0E-65 T 09-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14395 c10107161b20658ab866b336a7dfe2dc 155 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 7.3E-66 T 09-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS15005 469753515856e3391dd0782a037e199c 211 Pfam PF03358 NADPH-dependent FMN reductase 1 156 1.2E-29 T 09-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOSPO_RS15005 469753515856e3391dd0782a037e199c 211 SUPERFAMILY SSF52218 1 193 1.71E-45 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS15005 469753515856e3391dd0782a037e199c 211 Gene3D G3DSA:3.40.50.360 1 184 1.7E-39 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS15005 469753515856e3391dd0782a037e199c 211 PANTHER PTHR10204:SF43 1 207 5.4E-129 T 09-11-2016 CLOSPO_RS15005 469753515856e3391dd0782a037e199c 211 PANTHER PTHR10204 1 207 5.4E-129 T 09-11-2016 CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 273 6.6E-83 T 09-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 PANTHER PTHR20861:SF2 5 279 2.3E-99 T 09-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 Gene3D G3DSA:3.30.70.890 163 279 2.4E-32 T 09-11-2016 IPR013750 GHMP kinase, C-terminal domain CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 SUPERFAMILY SSF54211 3 155 6.68E-43 T 09-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 Pfam PF08544 GHMP kinases C terminal 195 272 1.6E-9 T 09-11-2016 IPR013750 GHMP kinase, C-terminal domain CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 Pfam PF00288 GHMP kinases N terminal domain 83 141 1.0E-5 T 09-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 SUPERFAMILY SSF55060 160 279 4.6E-27 T 09-11-2016 IPR013750 GHMP kinase, C-terminal domain CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 1 277 34.099 T 09-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 PANTHER PTHR20861 5 279 2.3E-99 T 09-11-2016 CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 Gene3D G3DSA:3.30.230.10 3 155 2.6E-52 T 09-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOSPO_RS14120 41e9f1312a455b6cb8d7013a6b7f6e5d 280 PIRSF PIRSF010376 1 280 3.5E-93 T 09-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 PANTHER PTHR21666 1 324 1.1E-69 T 09-11-2016 CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 Gene3D G3DSA:2.40.40.10 283 332 3.7E-5 T 09-11-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 Pfam PF07501 G5 domain 155 229 5.4E-19 T 09-11-2016 IPR011098 G5 domain CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 PANTHER PTHR21666:SF181 1 324 1.1E-69 T 09-11-2016 CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 SMART SM01208 152 230 2.1E-23 T 09-11-2016 IPR011098 G5 domain CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 Pfam PF06725 3D domain 291 351 4.1E-22 T 09-11-2016 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 SUPERFAMILY SSF50685 290 339 8.02E-10 T 09-11-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 Pfam PF03990 Domain of unknown function (DUF348) 43 82 3.4E-9 T 09-11-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- CLOSPO_RS14335 3b1cc95c4112defb865b8e14c0fcfe56 352 Pfam PF03990 Domain of unknown function (DUF348) 99 138 1.5E-9 T 09-11-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 PANTHER PTHR24423:SF480 164 324 1.8E-45 T 09-11-2016 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 SUPERFAMILY SSF52172 169 298 2.99E-33 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 SMART SM00448 168 281 6.5E-28 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 PANTHER PTHR24423 164 324 1.8E-45 T 09-11-2016 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 Pfam PF00072 Response regulator receiver domain 170 281 3.5E-24 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 Pfam PF08448 PAS fold 20 132 3.1E-7 T 09-11-2016 IPR013656 PAS fold-4 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 SUPERFAMILY SSF47226 264 402 3.93E-15 T 09-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 Gene3D G3DSA:3.30.450.20 19 134 1.9E-5 T 09-11-2016 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 Gene3D G3DSA:1.20.120.160 315 411 2.6E-15 T 09-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 Gene3D G3DSA:3.40.50.2300 168 294 7.7E-37 T 09-11-2016 CLOSPO_RS15880 96455130a32df0dc71acc0ee4d1d6a2c 415 Pfam PF01627 Hpt domain 334 398 1.6E-5 T 09-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 PANTHER PTHR10996:SF168 1 313 3.5E-162 T 09-11-2016 CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 Gene3D G3DSA:3.40.50.720 5 113 1.5E-21 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 SUPERFAMILY SSF51735 98 279 2.04E-49 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 12 310 2.0E-11 T 09-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 Gene3D G3DSA:3.40.50.720 114 279 3.4E-54 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 PANTHER PTHR10996 1 313 3.5E-162 T 09-11-2016 CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 09-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 SUPERFAMILY SSF52283 3 149 1.06E-13 T 09-11-2016 CLOSPO_RS14880 88f036ddbaff95966e92828935c9e7fa 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 277 3.6E-52 T 09-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CLOSPO_RS18070 32a482824cf16963f1165ea05b3d1d51 173 Gene3D G3DSA:3.40.109.10 1 172 4.9E-42 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS18070 32a482824cf16963f1165ea05b3d1d51 173 PANTHER PTHR23026:SF117 1 172 6.0E-81 T 09-11-2016 CLOSPO_RS18070 32a482824cf16963f1165ea05b3d1d51 173 SUPERFAMILY SSF55469 2 167 1.44E-35 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS18070 32a482824cf16963f1165ea05b3d1d51 173 Pfam PF00881 Nitroreductase family 5 58 2.9E-10 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS18070 32a482824cf16963f1165ea05b3d1d51 173 Pfam PF00881 Nitroreductase family 67 149 1.4E-7 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS18070 32a482824cf16963f1165ea05b3d1d51 173 PANTHER PTHR23026 1 172 6.0E-81 T 09-11-2016 CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 PIRSF PIRSF006815 2 446 2.5E-194 T 09-11-2016 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 2 446 48.39 T 09-11-2016 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 PANTHER PTHR11773 3 444 1.8E-246 T 09-11-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 PANTHER PTHR11773:SF2 3 444 1.8E-246 T 09-11-2016 CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 Pfam PF02347 Glycine cleavage system P-protein 4 442 1.3E-142 T 09-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 SUPERFAMILY SSF53383 3 445 2.59E-109 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS16955 0f414ce7a62d111ab2423b58447b7a3b 446 Gene3D G3DSA:3.40.640.10 91 329 5.3E-21 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 3 390 3.7E-162 T 09-11-2016 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 SUPERFAMILY SSF52540 11 171 1.16E-27 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 PANTHER PTHR11649:SF59 4 319 1.3E-65 T 09-11-2016 CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 Gene3D G3DSA:3.40.50.300 5 168 5.4E-30 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 143 1.0E-20 T 09-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 PANTHER PTHR11649 4 319 1.3E-65 T 09-11-2016 CLOSPO_RS14925 abd9466eceb4fdaec3dae6fab53c671f 397 Pfam PF01926 50S ribosome-binding GTPase 12 126 8.3E-19 T 09-11-2016 IPR006073 GTP binding domain GO:0005525 CLOSPO_RS15700 e0e59de7c2fee5619c20b1f01f1c960e 182 SUPERFAMILY SSF55811 2 162 2.1E-26 T 09-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 CLOSPO_RS15700 e0e59de7c2fee5619c20b1f01f1c960e 182 PANTHER PTHR11839 4 164 3.3E-37 T 09-11-2016 CLOSPO_RS15700 e0e59de7c2fee5619c20b1f01f1c960e 182 Gene3D G3DSA:3.90.79.10 2 169 1.1E-35 T 09-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 CLOSPO_RS15700 e0e59de7c2fee5619c20b1f01f1c960e 182 Pfam PF00293 NUDIX domain 43 144 1.7E-6 T 09-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 CLOSPO_RS14445 1519471c1728f50a4544d20b90069f04 314 PANTHER PTHR11669 6 194 2.6E-53 T 09-11-2016 CLOSPO_RS14445 1519471c1728f50a4544d20b90069f04 314 SUPERFAMILY SSF52540 19 176 1.4E-35 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14445 1519471c1728f50a4544d20b90069f04 314 Gene3D G3DSA:3.40.50.300 6 150 1.6E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14445 1519471c1728f50a4544d20b90069f04 314 Pfam PF13177 DNA polymerase III, delta subunit 9 152 5.4E-32 T 09-11-2016 CLOSPO_RS14445 1519471c1728f50a4544d20b90069f04 314 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 232 312 5.8E-6 T 09-11-2016 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS14445 1519471c1728f50a4544d20b90069f04 314 PANTHER PTHR11669:SF8 6 194 2.6E-53 T 09-11-2016 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Pfam PF07517 SecA DEAD-like domain 5 382 5.6E-131 T 09-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 ProSitePatterns PS01312 SecA family signature. 480 495 - T 09-11-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SUPERFAMILY SSF52540 397 569 1.37E-52 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 781 19.933 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SUPERFAMILY SSF52540 348 395 3.49E-84 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SUPERFAMILY SSF52540 2 226 3.49E-84 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Gene3D G3DSA:3.90.1440.10 228 348 7.3E-46 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SMART SM00958 226 338 1.5E-65 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Gene3D G3DSA:1.10.3060.10 599 780 8.8E-54 T 09-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 99 113 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 393 406 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 168 188 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 115 125 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 356 373 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 319 341 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PRINTS PR00906 SecA protein signature 61 85 7.4E-68 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Pfam PF01043 SecA preprotein cross-linking domain 230 338 9.9E-41 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Pfam PF02810 SEC-C motif 815 833 8.8E-10 T 09-11-2016 IPR004027 SEC-C motif CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Pfam PF07516 SecA Wing and Scaffold domain 568 778 2.5E-67 T 09-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SUPERFAMILY SSF81767 225 348 1.57E-45 T 09-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Gene3D G3DSA:3.40.50.300 3 226 1.9E-124 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Gene3D G3DSA:3.40.50.300 349 395 1.9E-124 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SUPERFAMILY SSF81886 571 823 6.41E-79 T 09-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 5.3E-233 T 09-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 SMART SM00957 4 382 2.3E-277 T 09-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 PANTHER PTHR30612 3 835 0.0 T 09-11-2016 CLOSPO_RS13845 174aeff510634ddedfb835e4823ff3fa 835 Gene3D G3DSA:3.40.50.300 397 570 6.9E-81 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13275 cdba07f4bd1cdd943550fd3aabd693c6 160 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 13 138 1.8E-46 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13275 cdba07f4bd1cdd943550fd3aabd693c6 160 SUPERFAMILY SSF51261 3 159 1.74E-51 T 09-11-2016 IPR011055 Duplicated hybrid motif CLOSPO_RS13275 cdba07f4bd1cdd943550fd3aabd693c6 160 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 16 135 1.4E-40 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS13275 cdba07f4bd1cdd943550fd3aabd693c6 160 Gene3D G3DSA:2.70.70.10 4 158 8.5E-56 T 09-11-2016 CLOSPO_RS13275 cdba07f4bd1cdd943550fd3aabd693c6 160 PANTHER PTHR30175 1 110 5.8E-41 T 09-11-2016 CLOSPO_RS13275 cdba07f4bd1cdd943550fd3aabd693c6 160 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 77 89 - T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 Gene3D G3DSA:3.40.80.10 16 136 1.5E-42 T 09-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 SMART SM00644 5 132 6.4E-9 T 09-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 PANTHER PTHR11022 19 135 1.6E-35 T 09-11-2016 IPR015510 Peptidoglycan recognition protein GO:0008745|GO:0009253 CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 SUPERFAMILY SSF55846 14 135 2.09E-40 T 09-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 17 132 1.3E-18 T 09-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 PANTHER PTHR11022:SF41 19 135 1.6E-35 T 09-11-2016 CLOSPO_RS17170 886147717674252b3d27f36ce61d4ebb 158 SMART SM00701 6 126 6.4E-5 T 09-11-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 CLOSPO_RS16295 50bcf4e2653ea888e06b00f4c44f19c3 472 PIRSF PIRSF005353 1 471 1.4E-171 T 09-11-2016 IPR026033 Purine permease PbuG-like CLOSPO_RS16295 50bcf4e2653ea888e06b00f4c44f19c3 472 PANTHER PTHR11119:SF9 8 458 1.5E-134 T 09-11-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 CLOSPO_RS16295 50bcf4e2653ea888e06b00f4c44f19c3 472 Pfam PF00860 Permease family 27 430 9.8E-39 T 09-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS16295 50bcf4e2653ea888e06b00f4c44f19c3 472 PANTHER PTHR11119 8 458 1.5E-134 T 09-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 Pfam PF13353 4Fe-4S single cluster domain 132 244 1.5E-9 T 09-11-2016 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 401 487 1.1E-7 T 09-11-2016 IPR023885 4Fe4S-binding SPASM domain CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 Gene3D G3DSA:3.20.20.70 123 477 7.5E-49 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 SMART SM00729 125 349 0.0048 T 09-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 PANTHER PTHR11228 69 372 6.1E-46 T 09-11-2016 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 SUPERFAMILY SSF102114 375 466 8.37E-42 T 09-11-2016 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 SUPERFAMILY SSF102114 126 343 8.37E-42 T 09-11-2016 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 131 142 - T 09-11-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 PANTHER PTHR11228:SF21 393 497 6.1E-46 T 09-11-2016 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 PANTHER PTHR11228 393 497 6.1E-46 T 09-11-2016 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 Pfam PF04055 Radical SAM superfamily 131 285 2.8E-15 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS16565 ebc4274555d59b480a54dc898876c92d 521 PANTHER PTHR11228:SF21 69 372 6.1E-46 T 09-11-2016 CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 PANTHER PTHR24220 7 329 5.0E-155 T 09-11-2016 CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 SUPERFAMILY SSF52540 5 247 3.5E-88 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 PANTHER PTHR24220:SF150 7 329 5.0E-155 T 09-11-2016 CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 Gene3D G3DSA:3.40.50.300 4 238 8.5E-81 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 359 3.8E-123 T 09-11-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 Pfam PF08402 TOBE domain 281 358 2.7E-7 T 09-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 SMART SM00382 32 215 1.1E-19 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 SUPERFAMILY SSF50331 240 358 9.07E-10 T 09-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal CLOSPO_RS16150 db53807dad72661b9590e55bcbeb413c 360 Pfam PF00005 ABC transporter 24 165 9.9E-35 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 Gene3D G3DSA:3.30.450.40 36 203 4.5E-12 T 09-11-2016 IPR029016 GAF domain-like CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 PANTHER PTHR10799:SF750 1 100 1.3E-17 T 09-11-2016 CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 PANTHER PTHR10799 1 100 1.3E-17 T 09-11-2016 CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 205 352 1.6E-38 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 Gene3D G3DSA:3.30.70.270 209 352 6.2E-39 T 09-11-2016 CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 SUPERFAMILY SSF55781 36 202 1.45E-8 T 09-11-2016 IPR029016 GAF domain-like CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 SMART SM00267 196 355 1.7E-39 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 207 353 3.3E-38 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 SUPERFAMILY SSF55073 212 352 1.41E-36 T 09-11-2016 IPR029787 Nucleotide cyclase CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 PANTHER PTHR10799:SF750 235 351 1.3E-17 T 09-11-2016 CLOSPO_RS14275 791139eaa04c496d5caa516409e51d1e 356 PANTHER PTHR10799 235 351 1.3E-17 T 09-11-2016 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 Gene3D G3DSA:1.10.10.10 126 225 1.1E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 SUPERFAMILY SSF46894 125 225 5.67E-26 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 SUPERFAMILY SSF52172 3 118 4.13E-32 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 SMART SM00862 149 224 9.7E-21 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 PANTHER PTHR26402 2 230 2.4E-157 T 09-11-2016 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 Gene3D G3DSA:3.40.50.2300 3 120 7.2E-31 T 09-11-2016 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 SMART SM00448 2 112 1.3E-27 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 Pfam PF00072 Response regulator receiver domain 4 112 2.0E-21 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 2.2E-22 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13270 8df68d5c456e0a5c84f403d846427988 232 PANTHER PTHR26402:SF503 2 230 2.4E-157 T 09-11-2016 CLOSPO_RS16870 6f902a3bbb9e672b38706ee7097765fc 346 Gene3D G3DSA:1.10.3470.10 19 344 3.2E-96 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS16870 6f902a3bbb9e672b38706ee7097765fc 346 Pfam PF01032 FecCD transport family 31 341 4.8E-86 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS16870 6f902a3bbb9e672b38706ee7097765fc 346 SUPERFAMILY SSF81345 16 341 2.09E-78 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS16870 6f902a3bbb9e672b38706ee7097765fc 346 PANTHER PTHR30472 2 346 3.4E-183 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS16870 6f902a3bbb9e672b38706ee7097765fc 346 PANTHER PTHR30472:SF1 2 346 3.4E-183 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 PANTHER PTHR11911 55 187 1.7E-33 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 Pfam PF05239 PRC-barrel domain 6 59 5.6E-7 T 09-11-2016 IPR027275 PRC-barrel domain CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 PANTHER PTHR11911:SF23 55 187 1.7E-33 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 Pfam PF03448 MgtE intracellular N domain 186 287 8.6E-25 T 09-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 SUPERFAMILY SSF54631 288 406 1.08E-25 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 Gene3D G3DSA:3.10.580.10 282 407 6.5E-21 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 PANTHER PTHR11911 262 419 1.7E-33 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 SMART SM00924 186 289 4.1E-33 T 09-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 SUPERFAMILY SSF158791 159 286 2.49E-29 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 Gene3D G3DSA:1.25.60.10 155 281 3.6E-34 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 PANTHER PTHR11911:SF23 262 419 1.7E-33 T 09-11-2016 CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 Pfam PF00571 CBS domain 354 405 1.2E-8 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 Pfam PF00571 CBS domain 289 345 6.3E-7 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 SMART SM00116 296 349 2.5 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS13690 97ebe8e0882cc7634d21831830227a44 421 SMART SM00116 360 409 0.39 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS18605 bcd816794fc6d7e6a2dc7d0d24da17fc 258 PANTHER PTHR34385:SF1 12 257 1.7E-83 T 09-11-2016 CLOSPO_RS18605 bcd816794fc6d7e6a2dc7d0d24da17fc 258 Gene3D G3DSA:3.30.1380.10 108 181 4.6E-4 T 09-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain CLOSPO_RS18605 bcd816794fc6d7e6a2dc7d0d24da17fc 258 PANTHER PTHR34385 12 257 1.7E-83 T 09-11-2016 CLOSPO_RS18605 bcd816794fc6d7e6a2dc7d0d24da17fc 258 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 109 235 2.2E-42 T 09-11-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CLOSPO_RS18605 bcd816794fc6d7e6a2dc7d0d24da17fc 258 SUPERFAMILY SSF55166 93 244 4.19E-36 T 09-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 SUPERFAMILY SSF55874 181 346 6.94E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 Pfam PF00672 HAMP domain 47 112 2.3E-7 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 SMART SM00304 58 117 1.6E-6 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 SUPERFAMILY SSF158472 67 115 9.02E-8 T 09-11-2016 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 Gene3D G3DSA:1.10.287.130 117 188 2.9E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 SMART SM00388 125 192 2.9E-9 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 PANTHER PTHR24423:SF526 1 345 2.0E-82 T 09-11-2016 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 PANTHER PTHR24423 1 345 2.0E-82 T 09-11-2016 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 Gene3D G3DSA:3.30.565.10 194 346 6.5E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 SMART SM00387 238 346 1.4E-23 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 SUPERFAMILY SSF47384 108 192 5.69E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 Pfam PF00512 His Kinase A (phospho-acceptor) domain 126 190 1.9E-11 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 345 2.2E-16 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 7.3E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 327 7.3E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13305 2df40a0d6f10011b76b21b29d8643fd3 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 303 7.3E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS04995 984131b862afe817c2db89660a5bfa1c 359 PANTHER PTHR30489:SF0 58 359 8.1E-82 T 09-11-2016 CLOSPO_RS04995 984131b862afe817c2db89660a5bfa1c 359 Pfam PF02687 FtsX-like permease family 85 205 9.9E-19 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS04995 984131b862afe817c2db89660a5bfa1c 359 PANTHER PTHR30489 58 359 8.1E-82 T 09-11-2016 CLOSPO_RS18835 fae1e5a8aa20d91452b2a258500eb022 268 Gene3D G3DSA:3.60.15.10 1 256 1.6E-29 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18835 fae1e5a8aa20d91452b2a258500eb022 268 SUPERFAMILY SSF56281 13 244 1.14E-28 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18835 fae1e5a8aa20d91452b2a258500eb022 268 PANTHER PTHR13754 1 266 5.3E-93 T 09-11-2016 CLOSPO_RS18835 fae1e5a8aa20d91452b2a258500eb022 268 Pfam PF00753 Metallo-beta-lactamase superfamily 21 79 4.3E-10 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18835 fae1e5a8aa20d91452b2a258500eb022 268 PANTHER PTHR13754:SF13 1 266 5.3E-93 T 09-11-2016 CLOSPO_RS18970 54dbf8d5871959d14897f24bd6fd997b 287 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 219 4.5E-63 T 09-11-2016 IPR003740 Uncharacterised membrane protein YitT CLOSPO_RS18970 54dbf8d5871959d14897f24bd6fd997b 287 PIRSF PIRSF006483 1 287 1.7E-95 T 09-11-2016 IPR003740 Uncharacterised membrane protein YitT CLOSPO_RS18970 54dbf8d5871959d14897f24bd6fd997b 287 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 6.6E-22 T 09-11-2016 IPR019264 Domain of unknown function DUF2179 CLOSPO_RS18970 54dbf8d5871959d14897f24bd6fd997b 287 PANTHER PTHR33545:SF7 1 284 3.4E-144 T 09-11-2016 CLOSPO_RS18970 54dbf8d5871959d14897f24bd6fd997b 287 PANTHER PTHR33545 1 284 3.4E-144 T 09-11-2016 CLOSPO_RS18170 0347561bf67bc0130a57873cf0e31dd2 260 PIRSF PIRSF033579 1 260 2.0E-99 T 09-11-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CLOSPO_RS18170 0347561bf67bc0130a57873cf0e31dd2 260 SUPERFAMILY SSF53800 5 258 2.35E-81 T 09-11-2016 CLOSPO_RS18170 0347561bf67bc0130a57873cf0e31dd2 260 Pfam PF06180 Cobalt chelatase (CbiK) 6 259 2.9E-94 T 09-11-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CLOSPO_RS18170 0347561bf67bc0130a57873cf0e31dd2 260 Gene3D G3DSA:3.40.50.1400 177 243 4.5E-21 T 09-11-2016 CLOSPO_RS18170 0347561bf67bc0130a57873cf0e31dd2 260 Gene3D G3DSA:3.40.50.1400 3 156 1.1E-42 T 09-11-2016 CLOSPO_RS11125 46aa16b39958fb46e4de56f1dcd523d5 217 PANTHER PTHR30288:SF0 1 217 2.6E-14 T 09-11-2016 CLOSPO_RS11125 46aa16b39958fb46e4de56f1dcd523d5 217 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 139 216 3.8E-12 T 09-11-2016 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CLOSPO_RS11125 46aa16b39958fb46e4de56f1dcd523d5 217 PANTHER PTHR30288 1 217 2.6E-14 T 09-11-2016 CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 PANTHER PTHR37822 1 335 1.8E-133 T 09-11-2016 CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 SUPERFAMILY SSF102114 81 252 3.27E-6 T 09-11-2016 CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 Pfam PF04055 Radical SAM superfamily 83 245 1.6E-9 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 Gene3D G3DSA:3.80.30.20 84 176 6.2E-5 T 09-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 Gene3D G3DSA:3.80.30.20 241 271 6.2E-5 T 09-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 PANTHER PTHR37822:SF2 1 335 1.8E-133 T 09-11-2016 CLOSPO_RS13625 4074290220067ecdcb02a1a67222cd59 335 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 2 335 4.7E-165 T 09-11-2016 IPR023897 Spore photoproduct lyase GO:0003913 CLOSPO_RS14655 8c6d01aea285e66e3fcdfefd091926b7 94 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 9.7E-30 T 09-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOSPO_RS14655 8c6d01aea285e66e3fcdfefd091926b7 94 Gene3D G3DSA:3.30.70.60 1 94 2.5E-37 T 09-11-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CLOSPO_RS14655 8c6d01aea285e66e3fcdfefd091926b7 94 SUPERFAMILY SSF54995 1 93 1.83E-35 T 09-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOSPO_RS14655 8c6d01aea285e66e3fcdfefd091926b7 94 PANTHER PTHR21011 1 91 5.1E-31 T 09-11-2016 CLOSPO_RS14655 8c6d01aea285e66e3fcdfefd091926b7 94 Pfam PF01250 Ribosomal protein S6 3 91 1.9E-32 T 09-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOSPO_RS14655 8c6d01aea285e66e3fcdfefd091926b7 94 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 20.384 T 09-11-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOSPO_RS17490 b87e05647acb618ca479f791e3860369 258 Gene3D G3DSA:3.40.50.300 21 187 2.9E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17490 b87e05647acb618ca479f791e3860369 258 SUPERFAMILY SSF52540 29 201 3.97E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17490 b87e05647acb618ca479f791e3860369 258 Pfam PF02421 Ferrous iron transport protein B 28 181 3.9E-62 T 09-11-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS17490 b87e05647acb618ca479f791e3860369 258 PANTHER PTHR11649:SF37 20 187 1.4E-66 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS17490 b87e05647acb618ca479f791e3860369 258 PANTHER PTHR11649 20 187 1.4E-66 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 PANTHER PTHR37477:SF1 30 235 3.1E-54 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 SUPERFAMILY SSF159664 299 423 4.05E-31 T 09-11-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 Pfam PF01890 Cobalamin synthesis G C-terminus 306 421 7.1E-27 T 09-11-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 PANTHER PTHR37477 294 424 3.1E-54 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 Gene3D G3DSA:3.30.420.180 299 422 2.9E-28 T 09-11-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 SUPERFAMILY SSF159672 8 38 1.96E-54 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 SUPERFAMILY SSF159672 73 215 1.96E-54 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 SUPERFAMILY SSF159672 295 313 1.96E-54 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 Pfam PF11761 Cobalamin biosynthesis central region 168 204 1.6E-5 T 09-11-2016 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 PANTHER PTHR37477:SF1 294 424 3.1E-54 T 09-11-2016 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 Pfam PF11760 Cobalamin synthesis G N-terminal 82 162 5.4E-36 T 09-11-2016 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 CLOSPO_RS18150 7415cc5a94c4e8587b6c548e680af76b 424 PANTHER PTHR37477 30 235 3.1E-54 T 09-11-2016 CLOSPO_RS13980 c08bbec823a40ebd3a7f80276849bfa6 122 Pfam PF03899 ATP synthase I chain 11 104 3.2E-9 T 09-11-2016 IPR005598 ATP synthase protein I CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 SMART SM00388 247 311 6.5E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 SUPERFAMILY SSF55874 300 464 4.58E-44 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 SMART SM00304 193 246 1.7E-5 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 SMART SM00387 356 468 3.0E-36 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 3.4E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 3.4E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 3.4E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 3.4E-18 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 Gene3D G3DSA:3.30.565.10 298 464 1.8E-49 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 310 5.5E-12 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 Gene3D G3DSA:1.10.287.130 238 297 4.3E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 SUPERFAMILY SSF47384 232 310 3.34E-15 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 PANTHER PTHR24423 187 464 1.0E-78 T 09-11-2016 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 PANTHER PTHR24423 1 11 1.0E-78 T 09-11-2016 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 463 5.7E-26 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 Pfam PF00672 HAMP domain 174 243 1.7E-9 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS18680 c61626082693123b6f235ea4cb85e627 468 SUPERFAMILY SSF158472 195 243 4.97E-6 T 09-11-2016 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 PANTHER PTHR24093:SF210 1 266 2.1E-162 T 09-11-2016 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 PANTHER PTHR24093 1 266 2.1E-162 T 09-11-2016 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 Gene3D G3DSA:2.70.150.10 22 172 1.4E-25 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 SUPERFAMILY SSF81653 74 169 5.49E-23 T 09-11-2016 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 Pfam PF00122 E1-E2 ATPase 43 264 9.6E-63 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 PRINTS PR00941 Cadmium-transporting ATPase signature 137 153 1.1E-7 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 PRINTS PR00941 Cadmium-transporting ATPase signature 56 76 1.1E-7 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 PRINTS PR00941 Cadmium-transporting ATPase signature 156 170 1.1E-7 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 SUPERFAMILY SSF81665 172 266 9.02E-11 T 09-11-2016 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 SUPERFAMILY SSF81665 22 75 9.02E-11 T 09-11-2016 CLOSPO_RS03500 44d4bfdade742b734bb0d6af1922485d 266 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 42 265 1.7E-23 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS16220 aa7b7e06a247cd7b9e165ea289d39b2a 39 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 33 3.4E-17 T 09-11-2016 IPR027601 Cys-rich peptide, Clo7bot family CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 Pfam PF00005 ABC transporter 327 396 3.4E-15 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 SUPERFAMILY SSF52540 306 397 2.72E-22 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 Gene3D G3DSA:3.40.50.300 309 397 1.4E-22 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 Pfam PF00664 ABC transporter transmembrane region 2 265 2.3E-47 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 SUPERFAMILY SSF90123 1 293 1.83E-60 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 Gene3D G3DSA:1.20.1560.10 1 291 1.0E-60 T 09-11-2016 CLOSPO_RS04040 6a3c4ddaa146d9c805d10fc3d5604709 398 PANTHER PTHR24221 1 395 2.0E-94 T 09-11-2016 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 Gene3D G3DSA:3.40.50.1390 3 130 1.1E-25 T 09-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 Pfam PF00239 Resolvase, N terminal domain 4 144 4.1E-30 T 09-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 SUPERFAMILY SSF53041 3 143 7.32E-29 T 09-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 PANTHER PTHR30461 1 498 3.8E-63 T 09-11-2016 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 SMART SM00857 4 149 5.5E-43 T 09-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 Pfam PF07508 Recombinase 171 278 1.3E-21 T 09-11-2016 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 Pfam PF13408 Recombinase zinc beta ribbon domain 292 353 6.8E-12 T 09-11-2016 IPR025827 Recombinase zinc beta ribbon domain CLOSPO_RS13495 a4185f991be669cda66e492ecb32f99f 528 PANTHER PTHR30461:SF3 1 498 3.8E-63 T 09-11-2016 CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 Hamap MF_02040 Iron-sulfur cluster carrier protein. 22 276 33.35 T 09-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 274 1.3E-89 T 09-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 SUPERFAMILY SSF52540 24 257 1.66E-48 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 PANTHER PTHR23264:SF19 1 274 1.1E-103 T 09-11-2016 CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 Gene3D G3DSA:3.40.50.300 24 274 1.3E-85 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 PANTHER PTHR23264 1 274 1.1E-103 T 09-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein CLOSPO_RS14290 8c6004ba7db471209f0f2e9e16a85f3a 280 ProSitePatterns PS01215 Mrp family signature. 143 159 - T 09-11-2016 IPR000808 Mrp, conserved site GO:0005524 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 PANTHER PTHR11019:SF61 34 345 4.1E-98 T 09-11-2016 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 SMART SM00342 253 337 6.3E-21 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 306 321 2.8E-7 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 321 337 2.8E-7 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 SUPERFAMILY SSF46689 292 339 3.0E-13 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 Gene3D G3DSA:1.10.10.60 292 338 7.2E-18 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 PANTHER PTHR11019 34 345 4.1E-98 T 09-11-2016 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 Gene3D G3DSA:1.10.10.60 238 289 1.9E-4 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13125 0aa9ff7c2fcb77abd1dcc78c6433f6d6 345 Pfam PF12833 Helix-turn-helix domain 260 337 3.0E-18 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 PANTHER PTHR36432 2 81 1.3E-48 T 09-11-2016 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 PANTHER PTHR36432:SF4 2 81 1.3E-48 T 09-11-2016 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 3.6E-10 T 09-11-2016 IPR007159 SpoVT-AbrB domain GO:0003677 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 Gene3D G3DSA:2.10.260.10 1 52 4.2E-30 T 09-11-2016 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.0E-10 T 09-11-2016 IPR007159 SpoVT-AbrB domain GO:0003677 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 SUPERFAMILY SSF89447 1 53 2.75E-16 T 09-11-2016 CLOSPO_RS14410 ec6eee914919058cf4df8e3a45eaeff9 81 SMART SM00966 8 51 3.4E-9 T 09-11-2016 IPR007159 SpoVT-AbrB domain GO:0003677 CLOSPO_RS13165 1ad216699959a01b624c7fee2d121623 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 207 1.2E-49 T 09-11-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CLOSPO_RS13165 1ad216699959a01b624c7fee2d121623 215 Pfam PF01081 KDPG and KHG aldolase 8 199 9.5E-39 T 09-11-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CLOSPO_RS13165 1ad216699959a01b624c7fee2d121623 215 PANTHER PTHR30246 1 215 1.7E-104 T 09-11-2016 CLOSPO_RS13165 1ad216699959a01b624c7fee2d121623 215 PANTHER PTHR30246:SF4 1 215 1.7E-104 T 09-11-2016 CLOSPO_RS13165 1ad216699959a01b624c7fee2d121623 215 SUPERFAMILY SSF51569 3 209 1.36E-57 T 09-11-2016 CLOSPO_RS13165 1ad216699959a01b624c7fee2d121623 215 Gene3D G3DSA:3.20.20.70 3 212 2.7E-69 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS15455 0c8f614cd799712ff08b8df1a7b56ab8 71 Pfam PF04070 Domain of unknown function (DUF378) 3 59 5.2E-28 T 09-11-2016 IPR007211 Protein of unknown function DUF378 CLOSPO_RS15455 0c8f614cd799712ff08b8df1a7b56ab8 71 PANTHER PTHR37304 1 70 2.6E-32 T 09-11-2016 CLOSPO_RS15455 0c8f614cd799712ff08b8df1a7b56ab8 71 PANTHER PTHR37304:SF1 1 70 2.6E-32 T 09-11-2016 CLOSPO_RS17555 db778a8e09a4cec9077c82ca20062d5e 153 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 131 1.1E-45 T 09-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 CLOSPO_RS17555 db778a8e09a4cec9077c82ca20062d5e 153 PANTHER PTHR20941 1 153 1.1E-74 T 09-11-2016 CLOSPO_RS17555 db778a8e09a4cec9077c82ca20062d5e 153 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 87 98 - T 09-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 CLOSPO_RS17555 db778a8e09a4cec9077c82ca20062d5e 153 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 131 1.9E-39 T 09-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 CLOSPO_RS17555 db778a8e09a4cec9077c82ca20062d5e 153 Gene3D G3DSA:3.30.70.560 2 151 5.8E-58 T 09-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 CLOSPO_RS17555 db778a8e09a4cec9077c82ca20062d5e 153 SUPERFAMILY SSF55083 1 151 7.85E-54 T 09-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 SUPERFAMILY SSF82866 500 678 4.19E-26 T 09-11-2016 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 Gene3D G3DSA:1.20.1640.10 141 335 3.7E-27 T 09-11-2016 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 Gene3D G3DSA:1.20.1640.10 491 679 1.7E-26 T 09-11-2016 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 PANTHER PTHR33406 10 676 2.6E-49 T 09-11-2016 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 SUPERFAMILY SSF82866 136 333 2.49E-30 T 09-11-2016 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 Pfam PF03176 MMPL family 117 332 3.0E-33 T 09-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CLOSPO_RS12920 dc281fe5e61f910aeb9f950d4fb7af71 701 Pfam PF03176 MMPL family 476 679 4.7E-26 T 09-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 Pfam PF03129 Anticodon binding domain 372 459 2.2E-25 T 09-11-2016 IPR004154 Anticodon-binding CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 SUPERFAMILY SSF52954 359 461 4.08E-35 T 09-11-2016 IPR004154 Anticodon-binding CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 Gene3D G3DSA:3.30.930.10 8 92 3.9E-148 T 09-11-2016 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 Gene3D G3DSA:3.30.930.10 136 367 3.9E-148 T 09-11-2016 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 343 3.5E-10 T 09-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 407 426 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 203 220 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 327 339 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 220 230 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 150 162 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 171 188 1.2E-53 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 4 462 52.345 T 09-11-2016 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 Gene3D G3DSA:3.40.50.800 368 461 1.2E-39 T 09-11-2016 IPR004154 Anticodon-binding CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 PANTHER PTHR10745 7 459 6.8E-223 T 09-11-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 SUPERFAMILY SSF55681 6 375 1.38E-128 T 09-11-2016 CLOSPO_RS15310 2c07ac0b57087ccee50c5dc51a6e2f1a 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 245 1.7E-93 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 Pfam PF02743 Cache domain 394 559 1.7E-13 T 09-11-2016 IPR033479 Double Cache domain 1 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 SMART SM00283 156 417 2.2E-58 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 SUPERFAMILY SSF58104 162 430 1.74E-61 T 09-11-2016 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 SUPERFAMILY SSF58104 112 129 1.74E-61 T 09-11-2016 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 Gene3D G3DSA:3.30.450.20 464 559 5.7E-19 T 09-11-2016 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 196 415 1.1E-44 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 184 213 6.7E-11 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 312 6.7E-11 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 331 360 6.7E-11 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 SUPERFAMILY SSF103190 459 561 5.76E-11 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 Gene3D G3DSA:1.10.287.950 171 384 3.7E-49 T 09-11-2016 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 Gene3D G3DSA:1.10.287.950 385 460 8.0E-4 T 09-11-2016 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 PANTHER PTHR32089:SF1 57 434 1.2E-75 T 09-11-2016 CLOSPO_RS15515 bf929b7399788f7ff0d4b9f38e834ec2 563 PANTHER PTHR32089 57 434 1.2E-75 T 09-11-2016 CLOSPO_RS13645 5904bbd63e8f10a2024f906db6b58c7e 327 Gene3D G3DSA:3.40.50.1820 73 323 2.6E-45 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS13645 5904bbd63e8f10a2024f906db6b58c7e 327 Pfam PF12146 Serine aminopeptidase, S33 98 206 3.1E-7 T 09-11-2016 IPR022742 Serine aminopeptidase, S33 CLOSPO_RS13645 5904bbd63e8f10a2024f906db6b58c7e 327 SUPERFAMILY SSF53474 40 325 1.71E-40 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS13645 5904bbd63e8f10a2024f906db6b58c7e 327 Pfam PF09752 Uncharacterized conserved protein (DUF2048) 262 321 9.3E-5 T 09-11-2016 IPR019149 Abhydrolase domain containing 18 CLOSPO_RS13645 5904bbd63e8f10a2024f906db6b58c7e 327 PANTHER PTHR12277 16 217 1.3E-36 T 09-11-2016 CLOSPO_RS13645 5904bbd63e8f10a2024f906db6b58c7e 327 PANTHER PTHR12277 250 324 1.3E-36 T 09-11-2016 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 PANTHER PTHR23416 1 184 1.1E-97 T 09-11-2016 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 129 157 - T 09-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 PANTHER PTHR23416:SF55 1 184 1.1E-97 T 09-11-2016 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 154 1.4E-8 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 74 111 2.9E-5 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 PIRSF PIRSF000441 2 195 4.3E-83 T 09-11-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 SUPERFAMILY SSF51161 6 178 1.39E-56 T 09-11-2016 IPR011004 Trimeric LpxA-like CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 10 169 1.1E-74 T 09-11-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 Gene3D G3DSA:2.160.10.10 63 181 1.3E-35 T 09-11-2016 CLOSPO_RS13675 5afd09d9d8660dd5dc04eb5474ec32f4 198 Gene3D G3DSA:1.10.3130.10 6 62 3.2E-21 T 09-11-2016 CLOSPO_RS16510 540c3ef24fa9bc72bd5a10a7b0ce2f9e 128 SUPERFAMILY SSF54593 5 122 5.91E-25 T 09-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOSPO_RS16510 540c3ef24fa9bc72bd5a10a7b0ce2f9e 128 PANTHER PTHR10374:SF8 8 121 3.2E-14 T 09-11-2016 CLOSPO_RS16510 540c3ef24fa9bc72bd5a10a7b0ce2f9e 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 119 9.2E-17 T 09-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CLOSPO_RS16510 540c3ef24fa9bc72bd5a10a7b0ce2f9e 128 PANTHER PTHR10374 8 121 3.2E-14 T 09-11-2016 CLOSPO_RS16510 540c3ef24fa9bc72bd5a10a7b0ce2f9e 128 Gene3D G3DSA:3.10.180.10 7 121 3.8E-27 T 09-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 PANTHER PTHR33693:SF1 2 197 1.5E-53 T 09-11-2016 CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 SMART SM00987 28 189 1.1E-24 T 09-11-2016 CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 Pfam PF03167 Uracil DNA glycosylase superfamily 29 190 2.3E-36 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 Gene3D G3DSA:3.40.470.10 6 197 6.3E-44 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 SMART SM00986 28 189 1.1E-24 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 SUPERFAMILY SSF52141 10 195 3.6E-42 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS15365 b6253d7b00603ed2728284b4ffbaa907 198 PANTHER PTHR33693 2 197 1.5E-53 T 09-11-2016 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SUPERFAMILY SSF48452 144 222 1.12E-9 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SUPERFAMILY SSF48452 258 298 1.12E-9 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 Gene3D G3DSA:1.25.40.10 155 235 1.4E-14 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 Gene3D G3DSA:1.25.40.10 273 415 1.4E-14 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 Pfam PF12844 Helix-turn-helix domain 7 68 4.2E-11 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 Pfam PF13181 Tetratricopeptide repeat 385 416 3.4E-4 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 Pfam PF13181 Tetratricopeptide repeat 272 298 0.018 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SMART SM00028 148 181 130.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SMART SM00028 265 298 2.3 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SMART SM00028 188 221 440.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SMART SM00028 344 377 250.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SMART SM00028 384 417 0.014 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SUPERFAMILY SSF48452 259 416 3.72E-15 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 Gene3D G3DSA:1.10.260.40 6 85 2.0E-11 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SUPERFAMILY SSF47413 5 63 7.7E-11 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12625 538067d17d6c2833a019e0cf552a0c4d 417 SMART SM00530 9 63 6.6E-5 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 Gene3D G3DSA:3.40.50.1100 37 133 2.5E-43 T 09-11-2016 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 290 3.2E-74 T 09-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 302 6.2E-130 T 09-11-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 09-11-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 34 47 - T 09-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 302 1.4E-131 T 09-11-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 PANTHER PTHR10314 2 303 7.4E-139 T 09-11-2016 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 Gene3D G3DSA:3.40.50.1100 134 303 1.7E-75 T 09-11-2016 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 PANTHER PTHR10314:SF110 2 303 7.4E-139 T 09-11-2016 CLOSPO_RS13680 b16223ee7e9856d8aa6ac98698c40760 304 SUPERFAMILY SSF53686 2 302 1.07E-105 T 09-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOSPO_RS14105 51c8c923f00a0bc7c5a71bdb0716f7fb 367 SUPERFAMILY SSF81343 37 130 6.21E-7 T 09-11-2016 CLOSPO_RS14105 51c8c923f00a0bc7c5a71bdb0716f7fb 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 362 1.4E-67 T 09-11-2016 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CLOSPO_RS14105 51c8c923f00a0bc7c5a71bdb0716f7fb 367 Pfam PF03845 Spore germination protein 9 326 1.8E-57 T 09-11-2016 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CLOSPO_RS14105 51c8c923f00a0bc7c5a71bdb0716f7fb 367 PANTHER PTHR34975:SF2 1 367 7.8E-130 T 09-11-2016 CLOSPO_RS14105 51c8c923f00a0bc7c5a71bdb0716f7fb 367 PANTHER PTHR34975 1 367 7.8E-130 T 09-11-2016 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 Gene3D G3DSA:1.10.45.10 424 463 1.3E-15 T 09-11-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 Gene3D G3DSA:3.30.43.10 6 99 8.4E-27 T 09-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 Pfam PF01565 FAD binding domain 45 182 3.0E-42 T 09-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 SUPERFAMILY SSF56176 11 220 1.68E-68 T 09-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 SUPERFAMILY SSF55103 225 464 2.78E-58 T 09-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 Gene3D G3DSA:3.30.465.10 100 220 2.9E-41 T 09-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 PANTHER PTHR11748 11 464 3.2E-149 T 09-11-2016 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 Pfam PF02913 FAD linked oxidases, C-terminal domain 220 463 8.1E-66 T 09-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CLOSPO_RS18475 e2a20f8ef07bf49a65160009f62723fb 465 PANTHER PTHR11748:SF35 11 464 3.2E-149 T 09-11-2016 CLOSPO_RS15805 69bb1279b0a6f3da7145b5f6fd7d63f1 363 PANTHER PTHR24421:SF15 1 362 2.7E-55 T 09-11-2016 CLOSPO_RS15805 69bb1279b0a6f3da7145b5f6fd7d63f1 363 Gene3D G3DSA:3.30.565.10 219 242 6.9E-6 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15805 69bb1279b0a6f3da7145b5f6fd7d63f1 363 Gene3D G3DSA:3.30.565.10 275 324 6.9E-6 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15805 69bb1279b0a6f3da7145b5f6fd7d63f1 363 Pfam PF07730 Histidine kinase 174 239 8.1E-16 T 09-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CLOSPO_RS15805 69bb1279b0a6f3da7145b5f6fd7d63f1 363 SUPERFAMILY SSF55874 252 362 2.22E-7 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15805 69bb1279b0a6f3da7145b5f6fd7d63f1 363 PANTHER PTHR24421 1 362 2.7E-55 T 09-11-2016 CLOSPO_RS17680 430f3fedc8bf7f1c262d30f176754dbc 480 Gene3D G3DSA:3.40.50.1820 104 479 1.3E-133 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS17680 430f3fedc8bf7f1c262d30f176754dbc 480 SUPERFAMILY SSF53474 102 469 1.16E-46 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS17680 430f3fedc8bf7f1c262d30f176754dbc 480 PANTHER PTHR34043 5 471 4.9E-131 T 09-11-2016 CLOSPO_RS17680 430f3fedc8bf7f1c262d30f176754dbc 480 PANTHER PTHR34043:SF1 5 471 4.9E-131 T 09-11-2016 CLOSPO_RS11195 7d21cd00a023922099cca2176d9194e4 90 SUPERFAMILY SSF53335 2 58 5.87E-8 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS11195 7d21cd00a023922099cca2176d9194e4 90 Gene3D G3DSA:3.40.50.150 2 61 3.3E-7 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS18175 00cf41193724aa9a9be647562ffbd987 279 PIRSF PIRSF033887 1 276 4.0E-78 T 09-11-2016 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443|UniPathway: UPA00148 CLOSPO_RS18175 00cf41193724aa9a9be647562ffbd987 279 Gene3D G3DSA:3.30.230.10 33 122 1.4E-10 T 09-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOSPO_RS18175 00cf41193724aa9a9be647562ffbd987 279 Pfam PF00288 GHMP kinases N terminal domain 74 120 5.7E-8 T 09-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 CLOSPO_RS18175 00cf41193724aa9a9be647562ffbd987 279 PANTHER PTHR20861 57 174 4.6E-24 T 09-11-2016 CLOSPO_RS18175 00cf41193724aa9a9be647562ffbd987 279 SUPERFAMILY SSF54211 1 142 1.37E-18 T 09-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold CLOSPO_RS18175 00cf41193724aa9a9be647562ffbd987 279 PANTHER PTHR20861:SF5 57 174 4.6E-24 T 09-11-2016 CLOSPO_RS17395 9621d8bd146e2be1971cd6b1d810a07d 244 Pfam PF01881 CRISPR associated protein Cas6 94 242 1.2E-27 T 09-11-2016 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CLOSPO_RS17395 9621d8bd146e2be1971cd6b1d810a07d 244 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 45 241 8.2E-33 T 09-11-2016 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CLOSPO_RS17395 9621d8bd146e2be1971cd6b1d810a07d 244 PANTHER PTHR36984 1 244 3.1E-14 T 09-11-2016 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 SUPERFAMILY SSF51055 476 524 1.15E-9 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Pfam PF02839 Carbohydrate binding domain 398 437 6.6E-8 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Pfam PF02839 Carbohydrate binding domain 479 514 1.6E-7 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 PANTHER PTHR11177:SF203 34 376 1.2E-141 T 09-11-2016 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Pfam PF00704 Glycosyl hydrolases family 18 77 350 2.4E-10 T 09-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 SUPERFAMILY SSF51445 54 337 4.1E-22 T 09-11-2016 IPR017853 Glycoside hydrolase superfamily CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 PANTHER PTHR11177 34 376 1.2E-141 T 09-11-2016 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 SMART SM00495 478 526 8.7E-8 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 SMART SM00495 397 441 4.8E-9 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Gene3D G3DSA:2.10.10.20 476 525 8.3E-13 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Gene3D G3DSA:2.10.10.20 395 447 2.2E-15 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Gene3D G3DSA:3.20.20.80 79 251 6.3E-13 T 09-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 Gene3D G3DSA:3.20.20.80 287 337 6.3E-13 T 09-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CLOSPO_RS18925 53a99e9ad73f9613b8090464e077bb3d 527 SUPERFAMILY SSF51055 396 447 5.89E-11 T 09-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CLOSPO_RS16190 bff8c94b7d899d63180e1bedc0f6357c 116 Gene3D G3DSA:2.40.50.140 6 115 1.2E-29 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS16190 bff8c94b7d899d63180e1bedc0f6357c 116 PANTHER PTHR11586 2 115 1.5E-30 T 09-11-2016 CLOSPO_RS16190 bff8c94b7d899d63180e1bedc0f6357c 116 SUPERFAMILY SSF50249 9 115 8.81E-22 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS16190 bff8c94b7d899d63180e1bedc0f6357c 116 Pfam PF01588 Putative tRNA binding domain 19 113 2.2E-17 T 09-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 SMART SM00900 91 181 6.1E-32 T 09-11-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 3 183 25.634 T 09-11-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 PANTHER PTHR36118:SF1 2 185 2.1E-68 T 09-11-2016 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 PANTHER PTHR36118 2 185 2.1E-68 T 09-11-2016 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 10 183 7.3E-43 T 09-11-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 PIRSF PIRSF006091 1 190 4.6E-51 T 09-11-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CLOSPO_RS12815 4069850e3490624a7fff913feace6744 190 Pfam PF04205 FMN-binding domain 91 178 1.4E-23 T 09-11-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 PANTHER PTHR30514:SF1 1 244 1.3E-27 T 09-11-2016 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 SUPERFAMILY SSF46689 10 74 3.76E-14 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 Gene3D G3DSA:1.10.10.10 8 60 5.5E-14 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 SUPERFAMILY SSF53697 85 249 9.79E-25 T 09-11-2016 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 Pfam PF01380 SIS domain 116 240 5.0E-12 T 09-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 Gene3D G3DSA:3.40.50.10490 61 251 2.9E-28 T 09-11-2016 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 70 3.7E-10 T 09-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CLOSPO_RS13190 fe3a4b14396e98177473e0b369196640 253 PANTHER PTHR30514 1 244 1.3E-27 T 09-11-2016 CLOSPO_RS14910 667243aa97b61a3117a7a13f227c36f8 225 Pfam PF02811 PHP domain 4 85 1.1E-10 T 09-11-2016 IPR004013 PHP domain GO:0003824 CLOSPO_RS14910 667243aa97b61a3117a7a13f227c36f8 225 SUPERFAMILY SSF89550 1 195 1.7E-40 T 09-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 CLOSPO_RS14910 667243aa97b61a3117a7a13f227c36f8 225 Pfam PF13263 PHP-associated 139 192 1.0E-16 T 09-11-2016 CLOSPO_RS14910 667243aa97b61a3117a7a13f227c36f8 225 SMART SM00481 3 70 1.4E-9 T 09-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CLOSPO_RS14910 667243aa97b61a3117a7a13f227c36f8 225 Gene3D G3DSA:3.20.20.140 1 174 4.1E-25 T 09-11-2016 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 9.9E-42 T 09-11-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 Pfam PF00700 Bacterial flagellin C-terminal helical region 194 278 7.8E-20 T 09-11-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 PANTHER PTHR30244 1 283 1.0E-165 T 09-11-2016 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 SUPERFAMILY SSF64518 1 278 2.35E-87 T 09-11-2016 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 Gene3D G3DSA:1.20.1330.10 52 235 9.0E-62 T 09-11-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 PRINTS PR00207 Flagellin signature 109 132 2.2E-19 T 09-11-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 PRINTS PR00207 Flagellin signature 74 93 2.2E-19 T 09-11-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 PRINTS PR00207 Flagellin signature 35 52 2.2E-19 T 09-11-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOSPO_RS13455 79ab9fc0c407a6df2771d17d845caee6 283 PANTHER PTHR30244:SF17 1 283 1.0E-165 T 09-11-2016 CLOSPO_RS18315 6f309cbb9ecab924bc1724d74d416f83 147 Pfam PF13508 Acetyltransferase (GNAT) domain 34 113 6.3E-11 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18315 6f309cbb9ecab924bc1724d74d416f83 147 PANTHER PTHR23091:SF130 3 132 5.1E-15 T 09-11-2016 CLOSPO_RS18315 6f309cbb9ecab924bc1724d74d416f83 147 PANTHER PTHR23091 3 132 5.1E-15 T 09-11-2016 CLOSPO_RS18315 6f309cbb9ecab924bc1724d74d416f83 147 SUPERFAMILY SSF55729 9 145 2.06E-21 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18315 6f309cbb9ecab924bc1724d74d416f83 147 Gene3D G3DSA:3.40.630.30 13 139 1.8E-24 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 SUPERFAMILY SSF52343 91 257 8.51E-30 T 09-11-2016 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 SUPERFAMILY SSF63380 7 96 3.94E-17 T 09-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PANTHER PTHR19370:SF126 1 250 3.8E-157 T 09-11-2016 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 TIGRFAM TIGR02911 sulfite_red_B: sulfite reductase, subunit B 5 265 9.5E-150 T 09-11-2016 IPR014260 Sulphite reductase, subunit B UniPathway: UPA00370 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PANTHER PTHR19370 1 250 3.8E-157 T 09-11-2016 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 Gene3D G3DSA:3.40.50.80 88 224 4.0E-27 T 09-11-2016 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PIRSF PIRSF006816 6 264 2.8E-73 T 09-11-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UniPathway: UPA00070 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 Gene3D G3DSA:2.40.30.10 11 87 6.2E-11 T 09-11-2016 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 228 257 4.6E-7 T 09-11-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 Pfam PF00175 Oxidoreductase NAD-binding domain 109 209 5.4E-14 T 09-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 Gene3D G3DSA:2.10.240.10 228 257 1.1E-10 T 09-11-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PRINTS PR00406 Cytochrome B5 reductase signature 196 204 4.8E-6 T 09-11-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PRINTS PR00406 Cytochrome B5 reductase signature 83 97 4.8E-6 T 09-11-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PRINTS PR00406 Cytochrome B5 reductase signature 145 156 4.8E-6 T 09-11-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 CLOSPO_RS18200 007d9c0f4d1e30a05a3957795b1d71da 265 PRINTS PR00406 Cytochrome B5 reductase signature 107 126 4.8E-6 T 09-11-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 SUPERFAMILY SSF46955 9 129 2.12E-26 T 09-11-2016 IPR009061 Putative DNA-binding domain CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 3.3E-7 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 3.3E-7 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 3.3E-7 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 PANTHER PTHR30204 1 169 5.4E-42 T 09-11-2016 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 PANTHER PTHR30204:SF5 1 169 5.4E-42 T 09-11-2016 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 SUPERFAMILY SSF53335 217 373 2.15E-29 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 Gene3D G3DSA:1.10.1660.10 9 128 5.5E-28 T 09-11-2016 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 Pfam PF13411 MerR HTH family regulatory protein 9 76 2.7E-16 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 Gene3D G3DSA:3.40.50.150 223 444 2.9E-29 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 Pfam PF08241 Methyltransferase domain 229 326 7.1E-19 T 09-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17560 b9c9407cd8ceacc81cb69f402e5befc3 444 SMART SM00422 9 78 4.4E-20 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 SMART SM00893 74 262 1.4E-43 T 09-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 PANTHER PTHR10909 251 391 2.1E-38 T 09-11-2016 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 SUPERFAMILY SSF52467 273 391 2.66E-44 T 09-11-2016 IPR029035 DHS-like NAD/FAD-binding domain CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 PIRSF PIRSF000089 71 397 8.6E-101 T 09-11-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 274 355 1.6E-31 T 09-11-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 PANTHER PTHR10909:SF309 251 391 2.1E-38 T 09-11-2016 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 Gene3D G3DSA:3.30.70.20 20 64 9.6E-5 T 09-11-2016 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 Pfam PF01012 Electron transfer flavoprotein domain 76 247 4.7E-43 T 09-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 SUPERFAMILY SSF52402 73 267 6.98E-56 T 09-11-2016 CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 Gene3D G3DSA:3.40.50.620 73 265 1.2E-74 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS18470 a7ff975b47513b6ab7f5afe044e8f2f0 400 Gene3D G3DSA:3.40.50.1220 267 394 9.1E-49 T 09-11-2016 IPR029035 DHS-like NAD/FAD-binding domain CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 SUPERFAMILY SSF51230 79 155 2.75E-23 T 09-11-2016 IPR011053 Single hybrid motif CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 156 6.2E-40 T 09-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 Gene3D G3DSA:2.40.50.100 80 156 5.2E-27 T 09-11-2016 CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 Pfam PF00364 Biotin-requiring enzyme 82 155 5.8E-22 T 09-11-2016 IPR000089 Biotin/lipoyl attachment CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 112 129 - T 09-11-2016 IPR001882 Biotin-binding site CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 102 116 2.9E-17 T 09-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 85 98 2.9E-17 T 09-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 117 130 2.9E-17 T 09-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 PANTHER PTHR23151:SF64 1 156 2.1E-37 T 09-11-2016 CLOSPO_RS14855 5183fb2dda7e1dabb248dcb1c1a4ebab 158 PANTHER PTHR23151 1 156 2.1E-37 T 09-11-2016 CLOSPO_RS18035 954b3df5d7aa7c88a1ebbb50f5e7c195 183 SMART SM00860 26 164 8.1E-9 T 09-11-2016 IPR018958 SMI1/KNR4-like domain CLOSPO_RS18035 954b3df5d7aa7c88a1ebbb50f5e7c195 183 Gene3D G3DSA:3.40.1580.10 2 169 6.2E-29 T 09-11-2016 IPR018958 SMI1/KNR4-like domain CLOSPO_RS18035 954b3df5d7aa7c88a1ebbb50f5e7c195 183 SUPERFAMILY SSF160631 16 168 3.27E-28 T 09-11-2016 CLOSPO_RS18035 954b3df5d7aa7c88a1ebbb50f5e7c195 183 Pfam PF14568 SMI1-KNR4 cell-wall 28 162 5.9E-26 T 09-11-2016 CLOSPO_RS13210 bba0e30b8274b5f3f0abc53bd6cafdb1 143 SUPERFAMILY SSF46785 2 137 1.79E-33 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13210 bba0e30b8274b5f3f0abc53bd6cafdb1 143 Pfam PF02082 Transcriptional regulator 1 81 2.4E-24 T 09-11-2016 IPR000944 Transcription regulator Rrf2-type CLOSPO_RS13210 bba0e30b8274b5f3f0abc53bd6cafdb1 143 PANTHER PTHR33221:SF5 2 143 2.8E-75 T 09-11-2016 CLOSPO_RS13210 bba0e30b8274b5f3f0abc53bd6cafdb1 143 PANTHER PTHR33221 2 143 2.8E-75 T 09-11-2016 CLOSPO_RS13210 bba0e30b8274b5f3f0abc53bd6cafdb1 143 Gene3D G3DSA:1.10.10.10 1 142 1.3E-51 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17100 95f5783c7d2357c282789f707e1a75da 253 Gene3D G3DSA:3.60.15.10 4 234 2.1E-41 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS17100 95f5783c7d2357c282789f707e1a75da 253 Pfam PF00753 Metallo-beta-lactamase superfamily 26 211 5.8E-20 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS17100 95f5783c7d2357c282789f707e1a75da 253 SMART SM00849 25 211 1.2E-29 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS17100 95f5783c7d2357c282789f707e1a75da 253 PANTHER PTHR11935 1 211 8.6E-41 T 09-11-2016 CLOSPO_RS17100 95f5783c7d2357c282789f707e1a75da 253 PANTHER PTHR11935:SF106 1 211 8.6E-41 T 09-11-2016 CLOSPO_RS17100 95f5783c7d2357c282789f707e1a75da 253 SUPERFAMILY SSF56281 26 231 2.03E-42 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13750 a14f9652c67c7977f304af7749801b66 179 SMART SM01118 12 175 1.3E-6 T 09-11-2016 IPR023577 CYTH domain CLOSPO_RS13750 a14f9652c67c7977f304af7749801b66 179 Pfam PF01928 CYTH domain 2 167 6.6E-23 T 09-11-2016 IPR023577 CYTH domain CLOSPO_RS13750 a14f9652c67c7977f304af7749801b66 179 Gene3D G3DSA:2.40.320.10 3 174 2.3E-29 T 09-11-2016 IPR023577 CYTH domain CLOSPO_RS13750 a14f9652c67c7977f304af7749801b66 179 SUPERFAMILY SSF55154 3 173 4.09E-30 T 09-11-2016 IPR033469 CYTH-like domain CLOSPO_RS13750 a14f9652c67c7977f304af7749801b66 179 PANTHER PTHR21028 2 179 1.1E-38 T 09-11-2016 CLOSPO_RS13750 a14f9652c67c7977f304af7749801b66 179 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 3 140 8.0E-47 T 09-11-2016 CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 Gene3D G3DSA:3.40.50.1780 222 334 3.4E-41 T 09-11-2016 CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 Gene3D G3DSA:3.40.50.1780 123 177 3.4E-41 T 09-11-2016 CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 Pfam PF00037 4Fe-4S binding domain 114 135 8.1E-9 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 154 390 2.5E-61 T 09-11-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 PANTHER PTHR11615 78 449 2.6E-153 T 09-11-2016 CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 120 131 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 SUPERFAMILY SSF54862 94 139 6.65E-14 T 09-11-2016 CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 Gene3D G3DSA:3.30.70.20 66 122 2.6E-10 T 09-11-2016 CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 SUPERFAMILY SSF53920 119 427 6.28E-76 T 09-11-2016 IPR009016 Iron hydrogenase CLOSPO_RS15110 13502ac60f834d5e0802caa67a142656 449 PANTHER PTHR11615:SF158 78 449 2.6E-153 T 09-11-2016 CLOSPO_RS12645 fa9a2509abd8a71dccae7497279d978e 352 Pfam PF06803 Protein of unknown function (DUF1232) 223 259 1.6E-12 T 09-11-2016 IPR010652 Protein of unknown function DUF1232 UniPathway: UPA00143 CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 SMART SM00382 27 209 3.0E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 Pfam PF00005 ABC transporter 21 162 3.3E-32 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 Gene3D G3DSA:3.40.50.300 3 225 6.1E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 SUPERFAMILY SSF52540 4 218 6.01E-58 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 PANTHER PTHR24220:SF331 5 228 1.5E-135 T 09-11-2016 CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS18250 a180e12c629ec99284eee0c0a78d3c3e 295 PANTHER PTHR24220 5 228 1.5E-135 T 09-11-2016 CLOSPO_RS14285 8c043bc80958ee6684f0cc14182ff3f4 63 PANTHER PTHR36923:SF2 1 62 1.6E-24 T 09-11-2016 CLOSPO_RS14285 8c043bc80958ee6684f0cc14182ff3f4 63 PANTHER PTHR36923 1 62 1.6E-24 T 09-11-2016 CLOSPO_RS14285 8c043bc80958ee6684f0cc14182ff3f4 63 Gene3D G3DSA:3.30.70.20 1 60 1.6E-13 T 09-11-2016 CLOSPO_RS14285 8c043bc80958ee6684f0cc14182ff3f4 63 SUPERFAMILY SSF54862 1 60 5.74E-11 T 09-11-2016 CLOSPO_RS14285 8c043bc80958ee6684f0cc14182ff3f4 63 Pfam PF13459 4Fe-4S single cluster domain 3 60 9.8E-12 T 09-11-2016 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PIRSF PIRSF000724 1 398 2.7E-154 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 Gene3D G3DSA:3.40.50.1260 5 183 2.7E-73 T 09-11-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 7 397 42.632 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 SUPERFAMILY SSF53748 4 398 3.3E-159 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 17 27 - T 09-11-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PANTHER PTHR11406 4 398 1.7E-229 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 141 163 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 12 28 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 33 55 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 113 128 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 8.7E-96 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 Gene3D G3DSA:3.40.50.1270 184 385 1.4E-87 T 09-11-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS13570 7d48af94d457f97860210223eca7639d 398 Pfam PF00162 Phosphoglycerate kinase 8 387 1.1E-163 T 09-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 CLOSPO_RS14235 c92b9ce2ca432cb7221d621be3d3ca56 211 PANTHER PTHR15032 1 184 1.5E-78 T 09-11-2016 CLOSPO_RS14235 c92b9ce2ca432cb7221d621be3d3ca56 211 PANTHER PTHR15032:SF19 1 184 1.5E-78 T 09-11-2016 CLOSPO_RS14235 c92b9ce2ca432cb7221d621be3d3ca56 211 Pfam PF13483 Beta-lactamase superfamily domain 2 162 1.1E-43 T 09-11-2016 CLOSPO_RS14235 c92b9ce2ca432cb7221d621be3d3ca56 211 SUPERFAMILY SSF56281 1 185 4.55E-24 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS14235 c92b9ce2ca432cb7221d621be3d3ca56 211 Gene3D G3DSA:3.60.15.10 1 184 3.8E-43 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS16290 ad418ea66b3f1efa689981284122f62e 94 PANTHER PTHR37828:SF1 1 94 4.5E-23 T 09-11-2016 CLOSPO_RS16290 ad418ea66b3f1efa689981284122f62e 94 Gene3D G3DSA:3.30.70.1060 14 83 4.1E-7 T 09-11-2016 CLOSPO_RS16290 ad418ea66b3f1efa689981284122f62e 94 SUPERFAMILY SSF54909 1 84 1.18E-15 T 09-11-2016 IPR011008 Dimeric alpha-beta barrel CLOSPO_RS16290 ad418ea66b3f1efa689981284122f62e 94 Pfam PF03795 YCII-related domain 1 81 1.1E-12 T 09-11-2016 IPR005545 YCII-related CLOSPO_RS16290 ad418ea66b3f1efa689981284122f62e 94 PANTHER PTHR37828 1 94 4.5E-23 T 09-11-2016 CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 SUPERFAMILY SSF53335 12 276 1.44E-76 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 Gene3D G3DSA:1.10.8.100 207 276 2.7E-24 T 09-11-2016 IPR023165 rRNA adenine dimethylase-like CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 Gene3D G3DSA:3.40.50.150 5 202 8.4E-72 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 47 74 - T 09-11-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 272 4.7E-86 T 09-11-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 SMART SM00650 31 203 2.2E-79 T 09-11-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 273 2.5E-68 T 09-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 15 275 54.629 T 09-11-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CLOSPO_RS14325 17fe6fe74086b69bce5ffdaf11ba2717 278 PANTHER PTHR11727 6 277 3.4E-96 T 09-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 PANTHER PTHR33154:SF9 1 92 2.2E-31 T 09-11-2016 CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 Pfam PF12840 Helix-turn-helix domain 12 70 1.8E-11 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 SUPERFAMILY SSF46785 3 92 5.62E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 SMART SM00418 13 92 9.2E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 4.2E-9 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 4.2E-9 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 4.2E-9 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 PANTHER PTHR33154 1 92 2.2E-31 T 09-11-2016 CLOSPO_RS13805 955855999c4a4874d3f0efdc1edb3b18 93 Gene3D G3DSA:1.10.10.10 6 92 2.6E-26 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 PIRSF PIRSF004749 1 148 3.6E-43 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 Hamap MF_00163 Peptide deformylase [def]. 2 149 25.487 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 8 146 1.9E-43 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 SUPERFAMILY SSF56420 3 147 4.58E-49 T 09-11-2016 IPR023635 Peptide deformylase CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 PRINTS PR01576 Peptide deformylase signature 87 98 3.7E-26 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 PRINTS PR01576 Peptide deformylase signature 118 147 3.7E-26 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 PRINTS PR01576 Peptide deformylase signature 99 117 3.7E-26 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 PRINTS PR01576 Peptide deformylase signature 34 63 3.7E-26 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 Gene3D G3DSA:3.90.45.10 1 145 8.9E-50 T 09-11-2016 IPR023635 Peptide deformylase CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 Pfam PF01327 Polypeptide deformylase 4 146 3.2E-43 T 09-11-2016 IPR023635 Peptide deformylase CLOSPO_RS16065 5f7ca66b86b2a7503a657b153768fee9 150 PANTHER PTHR10458 1 143 1.9E-56 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS15940 71e3e20f7bba7c471326cf742399ae60 137 Gene3D G3DSA:1.20.120.50 1 131 3.9E-35 T 09-11-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CLOSPO_RS15940 71e3e20f7bba7c471326cf742399ae60 137 SUPERFAMILY SSF47188 1 131 9.42E-32 T 09-11-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CLOSPO_RS15940 71e3e20f7bba7c471326cf742399ae60 137 Pfam PF01814 Hemerythrin HHE cation binding domain 12 127 1.2E-11 T 09-11-2016 IPR012312 Haemerythrin-like CLOSPO_RS15940 71e3e20f7bba7c471326cf742399ae60 137 PANTHER PTHR37164 1 137 1.5E-40 T 09-11-2016 CLOSPO_RS15940 71e3e20f7bba7c471326cf742399ae60 137 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 3 131 1.7E-35 T 09-11-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CLOSPO_RS15940 71e3e20f7bba7c471326cf742399ae60 137 ProSitePatterns PS00550 Hemerythrin family signature. 59 82 - T 09-11-2016 IPR016131 Haemerythrin, iron-binding site GO:0046872 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Pfam PF00270 DEAD/DEAH box helicase 20 181 5.9E-20 T 09-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SMART SM00490 243 324 6.8E-28 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 PANTHER PTHR13710 1 611 2.4E-282 T 09-11-2016 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Pfam PF09382 RQC domain 402 512 2.7E-34 T 09-11-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 456 1.3E-148 T 09-11-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SUPERFAMILY SSF47819 516 598 9.38E-23 T 09-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Gene3D G3DSA:3.40.50.300 200 336 5.1E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SUPERFAMILY SSF46785 397 539 1.63E-36 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SMART SM00341 514 594 1.5E-17 T 09-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Pfam PF00570 HRDC domain 518 584 3.8E-22 T 09-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Pfam PF14493 Helix-turn-helix domain 614 701 1.5E-24 T 09-11-2016 IPR029491 Helicase Helix-turn-helix domain CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Gene3D G3DSA:1.10.10.10 337 513 1.0E-56 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Pfam PF16124 RecQ zinc-binding 336 398 7.2E-16 T 09-11-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 PANTHER PTHR13710:SF81 1 611 2.4E-282 T 09-11-2016 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Gene3D G3DSA:3.40.50.300 6 196 6.0E-55 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SMART SM00487 14 211 3.3E-31 T 09-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SUPERFAMILY SSF52540 57 345 1.17E-61 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 SMART SM00956 406 509 1.6E-43 T 09-11-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 6 587 8.8E-233 T 09-11-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Pfam PF00271 Helicase conserved C-terminal domain 218 324 6.2E-19 T 09-11-2016 IPR001650 Helicase, C-terminal CLOSPO_RS18395 4064c51affb13dc5e55476a2c7354c6c 709 Gene3D G3DSA:1.10.150.80 515 591 4.7E-25 T 09-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 09-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 SUPERFAMILY SSF53732 2 417 7.72E-151 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 Pfam PF00330 Aconitase family (aconitate hydratase) 7 407 2.5E-109 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 Gene3D G3DSA:3.40.1060.10 157 262 2.8E-36 T 09-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 SUPERFAMILY SSF52016 436 638 1.26E-55 T 09-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PRINTS PR00415 Aconitase family signature 110 123 2.4E-23 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PRINTS PR00415 Aconitase family signature 186 199 2.4E-23 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PRINTS PR00415 Aconitase family signature 200 213 2.4E-23 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PRINTS PR00415 Aconitase family signature 349 362 2.4E-23 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PRINTS PR00415 Aconitase family signature 90 98 2.4E-23 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PRINTS PR00415 Aconitase family signature 124 139 2.4E-23 T 09-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 09-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 4 638 8.8E-279 T 09-11-2016 IPR006250 Aconitase, putative CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 Gene3D G3DSA:3.30.499.10 270 459 1.4E-58 T 09-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 Pfam PF00694 Aconitase C-terminal domain 514 575 6.3E-25 T 09-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 Gene3D G3DSA:3.20.19.10 460 640 1.1E-47 T 09-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 Gene3D G3DSA:3.30.499.10 3 156 1.2E-47 T 09-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PANTHER PTHR11670 2 641 1.3E-273 T 09-11-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 CLOSPO_RS15435 f4471cfdf98be0847f3b768a49617b18 641 PANTHER PTHR11670:SF30 2 641 1.3E-273 T 09-11-2016 CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 SMART SM00487 65 275 0.0015 T 09-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 SUPERFAMILY SSF52540 89 255 8.68E-17 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 SUPERFAMILY SSF52540 11 24 8.68E-17 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 Pfam PF04851 Type III restriction enzyme, res subunit 10 252 5.1E-19 T 09-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 SUPERFAMILY SSF52540 470 569 3.19E-9 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 SUPERFAMILY SSF52540 92 130 3.19E-9 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16720 ce4e5eab217ff99b45888b61e7b916ad 982 Gene3D G3DSA:3.40.50.300 90 254 6.3E-14 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Gene3D G3DSA:3.40.50.300 293 374 2.9E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Gene3D G3DSA:3.40.50.300 503 578 2.9E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Gene3D G3DSA:3.40.50.300 162 278 5.2E-41 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 SUPERFAMILY SSF52540 296 577 1.54E-48 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Gene3D G3DSA:1.10.8.280 1 90 1.2E-25 T 09-11-2016 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 1 579 1.3E-290 T 09-11-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Gene3D G3DSA:1.20.1580.10 376 502 5.8E-57 T 09-11-2016 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Pfam PF00005 ABC transporter 470 542 1.7E-5 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 PANTHER PTHR32282:SF2 1 579 0.0 T 09-11-2016 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 PANTHER PTHR32282 1 579 0.0 T 09-11-2016 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 Gene3D G3DSA:1.20.1580.10 91 161 8.9E-24 T 09-11-2016 CLOSPO_RS07495 770f56f56ca13edb52c95f6283ff4547 579 SUPERFAMILY SSF52540 133 273 7.79E-24 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 SUPERFAMILY SSF52788 1 144 5.36E-32 T 09-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 5.8E-6 T 09-11-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 5.8E-6 T 09-11-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 Gene3D G3DSA:3.40.50.270 1 147 1.9E-34 T 09-11-2016 CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 PANTHER PTHR11717 1 150 1.5E-52 T 09-11-2016 CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 ProDom PD002938 VP2 CAPSID OUTER STRUCTURAL L2 PROTEIN NEUTRALIZATION EPITOPE NEUTRALIZING DIRECT 51 118 0.004 T 09-11-2016 IPR001742 Outer capsid protein VP2, Orbivirus GO:0005198|GO:0019028 CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 135 6.5E-26 T 09-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 SMART SM00226 1 143 1.2E-23 T 09-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily CLOSPO_RS14010 b9547cdac8103a44621f694d562534ff 150 PANTHER PTHR11717:SF14 1 150 1.5E-52 T 09-11-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CLOSPO_RS17540 f14b56947916c0c9e6e6e8c0736a853a 117 PIRSF PIRSF006113 1 117 3.3E-35 T 09-11-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein CLOSPO_RS17540 f14b56947916c0c9e6e6e8c0736a853a 117 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 89 1.4E-30 T 09-11-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein CLOSPO_RS17540 f14b56947916c0c9e6e6e8c0736a853a 117 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 116 6.5E-37 T 09-11-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein CLOSPO_RS17540 f14b56947916c0c9e6e6e8c0736a853a 117 SUPERFAMILY SSF55620 1 116 8.34E-39 T 09-11-2016 CLOSPO_RS17540 f14b56947916c0c9e6e6e8c0736a853a 117 Gene3D G3DSA:3.30.479.10 1 116 3.2E-39 T 09-11-2016 CLOSPO_RS17540 f14b56947916c0c9e6e6e8c0736a853a 117 PANTHER PTHR12589 1 115 7.8E-44 T 09-11-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 Gene3D G3DSA:3.30.70.270 194 357 1.9E-50 T 09-11-2016 CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 Pfam PF00990 Diguanylate cyclase, GGDEF domain 193 350 5.8E-48 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 SUPERFAMILY SSF55073 197 356 1.26E-47 T 09-11-2016 IPR029787 Nucleotide cyclase CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 SMART SM00471 387 522 4.8E-9 T 09-11-2016 IPR003607 HD/PDEase domain CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 PANTHER PTHR10799 48 353 3.0E-32 T 09-11-2016 CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 PANTHER PTHR10799 384 485 3.0E-32 T 09-11-2016 CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 SUPERFAMILY SSF109604 377 551 1.16E-37 T 09-11-2016 CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 Pfam PF01966 HD domain 391 513 2.8E-19 T 09-11-2016 IPR006674 HD domain CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 354 4.5E-55 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 SMART SM00267 181 355 3.0E-60 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 Gene3D G3DSA:1.10.3210.10 387 551 1.8E-22 T 09-11-2016 IPR006674 HD domain CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 PANTHER PTHR10799:SF750 48 353 3.0E-32 T 09-11-2016 CLOSPO_RS13010 96f49b20fa5ad43c139162f374c79b45 565 PANTHER PTHR10799:SF750 384 485 3.0E-32 T 09-11-2016 CLOSPO_RS12690 489320e6a88bc7dcad8b8e9f557a50cb 231 Pfam PF01863 Protein of unknown function DUF45 21 225 5.9E-58 T 09-11-2016 IPR002725 Protein of unknown function DUF45 CLOSPO_RS12690 489320e6a88bc7dcad8b8e9f557a50cb 231 PANTHER PTHR30399 2 231 6.7E-53 T 09-11-2016 CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 SMART SM00100 14 131 2.3E-13 T 09-11-2016 IPR000595 Cyclic nucleotide-binding domain CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 Pfam PF13545 Crp-like helix-turn-helix domain 152 224 9.6E-16 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 Gene3D G3DSA:2.60.120.10 9 144 8.6E-32 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 PANTHER PTHR24567:SF32 1 227 4.6E-86 T 09-11-2016 CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 SUPERFAMILY SSF46785 149 226 3.45E-20 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 SMART SM00419 170 218 1.6E-7 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 Gene3D G3DSA:1.10.10.10 148 226 1.7E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 SUPERFAMILY SSF51206 9 143 7.73E-30 T 09-11-2016 IPR018490 Cyclic nucleotide-binding-like CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 PANTHER PTHR24567 1 227 4.6E-86 T 09-11-2016 CLOSPO_RS18185 c69df4befadf53b4b7add394f2e7f8f5 229 Pfam PF00027 Cyclic nucleotide-binding domain 34 116 5.0E-13 T 09-11-2016 IPR000595 Cyclic nucleotide-binding domain CLOSPO_RS18085 fe3e5693abc19800b95ba8cd5529f32e 147 Gene3D G3DSA:1.20.950.20 2 70 9.1E-4 T 09-11-2016 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 PANTHER PTHR11082 1 322 2.0E-145 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 PANTHER PTHR11082:SF25 1 322 2.0E-145 T 09-11-2016 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 95 113 - T 09-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 Pfam PF01207 Dihydrouridine synthase (Dus) 14 313 2.1E-96 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 Gene3D G3DSA:3.20.20.70 8 245 1.8E-88 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 PIRSF PIRSF006621 1 321 3.0E-107 T 09-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 SUPERFAMILY SSF51395 10 313 3.66E-89 T 09-11-2016 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 316 9.9E-115 T 09-11-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CLOSPO_RS15290 e99efd6783ee5f14f1a00e4577a2fafe 323 Gene3D G3DSA:1.10.1200.80 251 317 1.1E-18 T 09-11-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 PANTHER PTHR24220:SF539 3 389 7.4E-146 T 09-11-2016 CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 SMART SM00382 30 217 9.5E-17 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 SUPERFAMILY SSF52540 1 225 9.85E-72 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 Pfam PF00005 ABC transporter 21 169 1.3E-31 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 Pfam PF02687 FtsX-like permease family 661 779 2.1E-21 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 Gene3D G3DSA:3.40.50.300 1 224 2.6E-73 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17895 b5c6c1c8450ebeab9ac64c704549fe2f 786 PANTHER PTHR24220 3 389 7.4E-146 T 09-11-2016 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 SMART SM01245 5 57 2.1E-25 T 09-11-2016 IPR032782 Jag, N-terminal CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 Gene3D G3DSA:3.30.300.120 59 137 2.4E-26 T 09-11-2016 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 PANTHER PTHR35800 2 208 1.5E-70 T 09-11-2016 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 Pfam PF14804 Jag N-terminus 7 54 5.7E-21 T 09-11-2016 IPR032782 Jag, N-terminal CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 Pfam PF13083 KH domain 62 131 4.4E-20 T 09-11-2016 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 Pfam PF01424 R3H domain 145 204 1.6E-17 T 09-11-2016 IPR001374 R3H domain GO:0003676 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 SMART SM00393 127 206 5.4E-19 T 09-11-2016 IPR001374 R3H domain GO:0003676 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 Gene3D G3DSA:3.30.1370.50 138 207 6.9E-31 T 09-11-2016 IPR001374 R3H domain GO:0003676 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 SUPERFAMILY SSF82708 148 203 8.44E-9 T 09-11-2016 IPR001374 R3H domain GO:0003676 CLOSPO_RS14570 97d57634dc3fc61f0801056e23ee44f4 208 Gene3D G3DSA:3.30.30.80 1 57 2.2E-24 T 09-11-2016 IPR032782 Jag, N-terminal CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 SMART SM00382 30 214 3.4E-7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 PANTHER PTHR24220:SF523 7 224 1.9E-93 T 09-11-2016 CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 PANTHER PTHR24220 7 224 1.9E-93 T 09-11-2016 CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 Gene3D G3DSA:3.40.50.300 2 232 6.1E-62 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 SUPERFAMILY SSF52540 3 228 1.24E-57 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 Pfam PF00005 ABC transporter 21 162 3.9E-30 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13440 bf4187909790798710cc9d714b4c06a7 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 SUPERFAMILY SSF53901 2 250 2.2E-76 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 PANTHER PTHR11712 2 410 1.8E-204 T 09-11-2016 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.0E-59 T 09-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 Gene3D G3DSA:3.40.47.10 1 258 2.2E-77 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 SMART SM00825 Beta-ketoacyl synthase 5 410 1.5E-14 T 09-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 9.5E-40 T 09-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 Gene3D G3DSA:3.40.47.10 262 410 5.8E-61 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 PIRSF PIRSF000447 1 412 1.5E-184 T 09-11-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 SUPERFAMILY SSF53901 213 410 8.39E-71 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14850 190981e6944eb084e744ea0556d65c39 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 1.6E-195 T 09-11-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 Pfam PF00005 ABC transporter 273 429 4.8E-17 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 Pfam PF00005 ABC transporter 21 169 2.6E-31 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 SUPERFAMILY SSF52540 3 226 5.32E-57 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 SUPERFAMILY SSF52540 256 489 4.79E-44 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 Gene3D G3DSA:3.40.50.300 254 494 4.5E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 Gene3D G3DSA:3.40.50.300 2 227 3.0E-62 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 SMART SM00382 29 217 4.5E-14 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 PANTHER PTHR24220 6 382 4.5E-210 T 09-11-2016 CLOSPO_RS13605 52a8bfaa47d3d334094adb83961cbab9 510 PANTHER PTHR24220:SF239 6 382 4.5E-210 T 09-11-2016 CLOSPO_RS18935 50eb56a19881c01fccf4881f67025b80 213 SUPERFAMILY SSF161098 4 203 4.84E-44 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS18935 50eb56a19881c01fccf4881f67025b80 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 212 2.3E-21 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS18935 50eb56a19881c01fccf4881f67025b80 213 Gene3D G3DSA:1.10.3720.10 4 212 9.1E-40 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS18935 50eb56a19881c01fccf4881f67025b80 213 PANTHER PTHR30450:SF1 1 213 1.3E-112 T 09-11-2016 CLOSPO_RS18935 50eb56a19881c01fccf4881f67025b80 213 PANTHER PTHR30450 1 213 1.3E-112 T 09-11-2016 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 Gene3D G3DSA:2.30.42.10 300 388 4.4E-23 T 09-11-2016 IPR001478 PDZ domain GO:0005515 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 Pfam PF13180 PDZ domain 298 381 8.3E-15 T 09-11-2016 IPR001478 PDZ domain GO:0005515 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 Pfam PF13365 Trypsin-like peptidase domain 126 262 1.0E-32 T 09-11-2016 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 SMART SM00228 297 373 1.0E-9 T 09-11-2016 IPR001478 PDZ domain GO:0005515 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PRINTS PR00834 HtrA/DegQ protease family signature 233 250 4.5E-37 T 09-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PRINTS PR00834 HtrA/DegQ protease family signature 156 176 4.5E-37 T 09-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PRINTS PR00834 HtrA/DegQ protease family signature 135 147 4.5E-37 T 09-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PRINTS PR00834 HtrA/DegQ protease family signature 331 343 4.5E-37 T 09-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PRINTS PR00834 HtrA/DegQ protease family signature 255 272 4.5E-37 T 09-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PRINTS PR00834 HtrA/DegQ protease family signature 196 220 4.5E-37 T 09-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 SUPERFAMILY SSF50494 95 305 1.72E-58 T 09-11-2016 IPR009003 Peptidase S1, PA clan CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PANTHER PTHR22939:SF79 65 390 4.5E-115 T 09-11-2016 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 SUPERFAMILY SSF50156 278 381 4.6E-20 T 09-11-2016 IPR001478 PDZ domain GO:0005515 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 Gene3D G3DSA:2.40.10.10 88 190 1.6E-35 T 09-11-2016 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 Gene3D G3DSA:2.40.10.10 191 299 7.7E-42 T 09-11-2016 CLOSPO_RS15160 75341642f7c60c6b3f0cfda5b4ca5d42 390 PANTHER PTHR22939 65 390 4.5E-115 T 09-11-2016 CLOSPO_RS15185 5962fc824e0708ac620971b16529ed20 511 PANTHER PTHR30250:SF6 1 511 3.2E-199 T 09-11-2016 CLOSPO_RS15185 5962fc824e0708ac620971b16529ed20 511 Pfam PF01943 Polysaccharide biosynthesis protein 6 301 8.1E-38 T 09-11-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CLOSPO_RS15185 5962fc824e0708ac620971b16529ed20 511 PANTHER PTHR30250 1 511 3.2E-199 T 09-11-2016 CLOSPO_RS15185 5962fc824e0708ac620971b16529ed20 511 PIRSF PIRSF038958 1 511 7.2E-156 T 09-11-2016 IPR024923 Peptidoglycan biosynthesis protein, SpoVB type CLOSPO_RS15185 5962fc824e0708ac620971b16529ed20 511 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 354 497 1.2E-25 T 09-11-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CLOSPO_RS18695 140a3f095466bf301e0ba5dd863a81ae 316 SUPERFAMILY SSF81345 5 312 1.96E-53 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS18695 140a3f095466bf301e0ba5dd863a81ae 316 PANTHER PTHR30472:SF19 15 316 1.0E-149 T 09-11-2016 CLOSPO_RS18695 140a3f095466bf301e0ba5dd863a81ae 316 Pfam PF01032 FecCD transport family 21 312 8.1E-49 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS18695 140a3f095466bf301e0ba5dd863a81ae 316 Gene3D G3DSA:1.10.3470.10 23 314 5.7E-52 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS18695 140a3f095466bf301e0ba5dd863a81ae 316 PANTHER PTHR30472 15 316 1.0E-149 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS17685 b65f0990b3301439bae30b13c64bdb39 192 PANTHER PTHR31223:SF0 1 189 9.3E-100 T 09-11-2016 CLOSPO_RS17685 b65f0990b3301439bae30b13c64bdb39 192 PANTHER PTHR31223 1 189 9.3E-100 T 09-11-2016 CLOSPO_RS17685 b65f0990b3301439bae30b13c64bdb39 192 Gene3D G3DSA:3.40.50.450 2 184 2.2E-67 T 09-11-2016 CLOSPO_RS17685 b65f0990b3301439bae30b13c64bdb39 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 6.8E-67 T 09-11-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CLOSPO_RS17685 b65f0990b3301439bae30b13c64bdb39 192 SUPERFAMILY SSF102405 1 179 1.48E-58 T 09-11-2016 CLOSPO_RS17685 b65f0990b3301439bae30b13c64bdb39 192 Pfam PF03641 Possible lysine decarboxylase 46 176 1.8E-42 T 09-11-2016 IPR031100 LOG family CLOSPO_RS17470 ca1b5b9068521d9db1e93c110481e304 437 PANTHER PTHR30588 1 436 1.6E-203 T 09-11-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CLOSPO_RS17470 ca1b5b9068521d9db1e93c110481e304 437 PANTHER PTHR30588:SF0 1 436 1.6E-203 T 09-11-2016 CLOSPO_RS17470 ca1b5b9068521d9db1e93c110481e304 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 412 4.7E-106 T 09-11-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CLOSPO_RS17470 ca1b5b9068521d9db1e93c110481e304 437 Pfam PF05525 Branched-chain amino acid transport protein 6 423 2.0E-122 T 09-11-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 63 7.1E-30 T 09-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 PRINTS PR00050 Cold shock protein signature 3 18 9.9E-18 T 09-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 PRINTS PR00050 Cold shock protein signature 23 32 9.9E-18 T 09-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 PRINTS PR00050 Cold shock protein signature 38 56 9.9E-18 T 09-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 Gene3D G3DSA:2.40.50.140 2 64 2.1E-30 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 SMART SM00357 2 65 4.9E-30 T 09-11-2016 IPR011129 Cold shock protein GO:0003676 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 PIRSF PIRSF002599 1 65 5.6E-23 T 09-11-2016 IPR012156 Cold shock, CspA GO:0003676 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 PANTHER PTHR11544 1 65 1.3E-37 T 09-11-2016 CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 SUPERFAMILY SSF50249 2 64 1.91E-23 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS13220 4db2e9e95d2c261a0d78972be34a53fd 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 09-11-2016 IPR019844 Cold-shock conserved site CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 Gene3D G3DSA:1.10.1660.10 2 117 6.5E-21 T 09-11-2016 CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 Pfam PF06445 GyrI-like small molecule binding domain 176 269 4.1E-9 T 09-11-2016 IPR029442 GyrI-like small molecule binding domain CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 SUPERFAMILY SSF46955 2 105 9.16E-21 T 09-11-2016 IPR009061 Putative DNA-binding domain CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 SMART SM00871 118 269 3.7E-12 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 SMART SM00422 2 72 6.7E-9 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 PANTHER PTHR30204:SF23 1 271 8.4E-77 T 09-11-2016 CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 SUPERFAMILY SSF55136 121 268 1.22E-14 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 Gene3D G3DSA:3.20.80.10 121 270 4.6E-10 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 Pfam PF13411 MerR HTH family regulatory protein 2 68 2.4E-10 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS16925 29787ca07923e0e21e438bceaca875b3 271 PANTHER PTHR30204 1 271 8.4E-77 T 09-11-2016 CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 13 326 1.7E-111 T 09-11-2016 IPR014255 Spore coat protein CotS CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 SUPERFAMILY SSF56112 9 329 2.79E-53 T 09-11-2016 IPR011009 Protein kinase-like domain CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 Gene3D G3DSA:3.90.1200.10 91 322 8.7E-75 T 09-11-2016 CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 Gene3D G3DSA:3.30.200.20 5 90 4.8E-25 T 09-11-2016 CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 Pfam PF01633 Choline/ethanolamine kinase 88 243 1.2E-12 T 09-11-2016 CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 PANTHER PTHR39179 7 330 2.4E-82 T 09-11-2016 CLOSPO_RS14155 bc582973c21d170b2b99f9663fc55c3c 334 PANTHER PTHR39179:SF1 7 330 2.4E-82 T 09-11-2016 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 PANTHER PTHR23406:SF23 20 390 7.4E-245 T 09-11-2016 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 PANTHER PTHR23406 20 390 7.4E-245 T 09-11-2016 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 SUPERFAMILY SSF51735 160 389 3.13E-81 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 Pfam PF03949 Malic enzyme, NAD binding domain 162 382 1.9E-29 T 09-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 Pfam PF00390 Malic enzyme, N-terminal domain 26 148 1.4E-29 T 09-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 SMART SM01274 15 148 1.8E-84 T 09-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 Gene3D G3DSA:3.40.50.10380 4 157 2.7E-58 T 09-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 09-11-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 Gene3D G3DSA:3.40.50.720 158 388 4.5E-85 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 SUPERFAMILY SSF53223 6 158 1.8E-57 T 09-11-2016 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 PIRSF PIRSF000106 16 390 1.4E-88 T 09-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CLOSPO_RS13655 4ea795f6719a7434dd9f2f9951a2e9e2 390 SMART SM00919 160 383 2.4E-132 T 09-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CLOSPO_RS15670 a286bbde48da6047d48ae644988f8008 174 Pfam PF12822 Protein of unknown function (DUF3816) 7 162 5.3E-17 T 09-11-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 640 3.6E-177 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 Pfam PF07670 Nucleoside recognition 515 643 4.3E-30 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 Pfam PF07670 Nucleoside recognition 354 448 1.7E-11 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 Pfam PF02421 Ferrous iron transport protein B 4 157 1.0E-66 T 09-11-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 PANTHER PTHR11649:SF37 263 679 6.5E-279 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 156 2.4E-12 T 09-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 6.4E-5 T 09-11-2016 IPR006073 GTP binding domain GO:0005525 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 6.4E-5 T 09-11-2016 IPR006073 GTP binding domain GO:0005525 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 1.3E-20 T 09-11-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 Gene3D G3DSA:3.40.50.300 3 178 1.6E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 PANTHER PTHR11649 1 145 6.5E-279 T 09-11-2016 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 PANTHER PTHR11649 263 679 6.5E-279 T 09-11-2016 CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 SUPERFAMILY SSF52540 3 165 9.94E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18590 c8250955dc61b8e45727272dfa4eef6c 718 PANTHER PTHR11649:SF37 1 145 6.5E-279 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 PANTHER PTHR11808 1 380 6.8E-202 T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 SUPERFAMILY SSF53383 8 377 1.48E-119 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 Gene3D G3DSA:3.40.640.10 2 243 3.2E-96 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 Gene3D G3DSA:3.90.1150.10 244 377 1.2E-50 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 377 4.1E-153 T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 PANTHER PTHR11808:SF49 1 380 6.8E-202 T 09-11-2016 CLOSPO_RS17070 92f1b04118adffab59c7ed88138b0a3e 380 PIRSF PIRSF001434 1 380 7.7E-144 T 09-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 CLOSPO_RS13170 f0cc27c1f1d68a97f9c7c5a1c88bc7b0 571 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 469 480 - T 09-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 CLOSPO_RS13170 f0cc27c1f1d68a97f9c7c5a1c88bc7b0 571 PANTHER PTHR21000:SF11 16 571 1.6E-266 T 09-11-2016 CLOSPO_RS13170 f0cc27c1f1d68a97f9c7c5a1c88bc7b0 571 Pfam PF00920 Dehydratase family 29 567 5.4E-183 T 09-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 CLOSPO_RS13170 f0cc27c1f1d68a97f9c7c5a1c88bc7b0 571 SUPERFAMILY SSF143975 10 380 2.48E-121 T 09-11-2016 CLOSPO_RS13170 f0cc27c1f1d68a97f9c7c5a1c88bc7b0 571 SUPERFAMILY SSF52016 382 570 3.06E-49 T 09-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CLOSPO_RS13170 f0cc27c1f1d68a97f9c7c5a1c88bc7b0 571 PANTHER PTHR21000 16 571 1.6E-266 T 09-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 CLOSPO_RS14095 a647f657f68eadb7ee3020c6613d7058 210 PANTHER PTHR22683:SF43 1 206 8.2E-102 T 09-11-2016 CLOSPO_RS14095 a647f657f68eadb7ee3020c6613d7058 210 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 38 163 2.3E-52 T 09-11-2016 IPR014202 Sporulation stage II, protein R CLOSPO_RS14095 a647f657f68eadb7ee3020c6613d7058 210 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 4 168 1.1E-67 T 09-11-2016 IPR014202 Sporulation stage II, protein R CLOSPO_RS14095 a647f657f68eadb7ee3020c6613d7058 210 PANTHER PTHR22683 1 206 8.2E-102 T 09-11-2016 CLOSPO_RS12970 8c77d1b583bfeb6f558561bfa55f0d23 288 PANTHER PTHR11807:SF16 25 278 4.6E-83 T 09-11-2016 CLOSPO_RS12970 8c77d1b583bfeb6f558561bfa55f0d23 288 PANTHER PTHR11807 25 278 4.6E-83 T 09-11-2016 CLOSPO_RS12970 8c77d1b583bfeb6f558561bfa55f0d23 288 Pfam PF01171 PP-loop family 55 218 1.5E-17 T 09-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal CLOSPO_RS12970 8c77d1b583bfeb6f558561bfa55f0d23 288 SUPERFAMILY SSF52402 31 232 1.79E-45 T 09-11-2016 CLOSPO_RS12970 8c77d1b583bfeb6f558561bfa55f0d23 288 PIRSF PIRSF004976 8 287 4.0E-69 T 09-11-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 CLOSPO_RS12970 8c77d1b583bfeb6f558561bfa55f0d23 288 Gene3D G3DSA:3.40.50.620 38 214 5.7E-19 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 Hamap MF_00984 Single-stranded DNA-binding protein. 1 105 26.961 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 PIRSF PIRSF002070 1 109 3.7E-31 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 Pfam PF00436 Single-strand binding protein family 1 101 1.3E-29 T 09-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 Gene3D G3DSA:2.40.50.140 1 105 9.7E-33 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 PANTHER PTHR10302 1 112 3.2E-33 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 SUPERFAMILY SSF50249 1 105 1.17E-32 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS12685 cd22efed2dc5ca076862db9d0a6e2594 112 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 104 9.9E-28 T 09-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 PANTHER PTHR11364 2 276 6.8E-88 T 09-11-2016 CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 Pfam PF00581 Rhodanese-like domain 7 126 3.4E-20 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 Pfam PF00581 Rhodanese-like domain 164 269 6.2E-9 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 SUPERFAMILY SSF52821 4 131 7.86E-32 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 Gene3D G3DSA:3.40.250.10 149 276 1.7E-23 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 Gene3D G3DSA:3.40.250.10 3 140 2.9E-39 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 PANTHER PTHR11364:SF0 2 276 6.8E-88 T 09-11-2016 CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 SMART SM00450 160 274 2.5E-11 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 SMART SM00450 5 131 8.7E-19 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS17440 59a77db901c2c468aba5c4f281170a21 279 SUPERFAMILY SSF52821 160 276 1.13E-20 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS16755 e015e54baba43ff4484a1a42e7e3d0d3 251 Pfam PF04282 Family of unknown function (DUF438) 9 74 5.3E-21 T 09-11-2016 IPR007380 Domain of unknown function DUF438 CLOSPO_RS16755 e015e54baba43ff4484a1a42e7e3d0d3 251 Gene3D G3DSA:1.20.120.520 80 248 7.7E-39 T 09-11-2016 CLOSPO_RS16755 e015e54baba43ff4484a1a42e7e3d0d3 251 PANTHER PTHR39966 75 235 5.3E-13 T 09-11-2016 CLOSPO_RS16755 e015e54baba43ff4484a1a42e7e3d0d3 251 Pfam PF01814 Hemerythrin HHE cation binding domain 84 220 5.1E-21 T 09-11-2016 IPR012312 Haemerythrin-like CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 220 233 - T 09-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 SUPERFAMILY SSF53383 15 371 1.08E-77 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 PANTHER PTHR11751 45 372 5.3E-112 T 09-11-2016 CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 Gene3D G3DSA:3.40.640.10 54 262 4.0E-53 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 Pfam PF00155 Aminotransferase class I and II 49 364 2.2E-44 T 09-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 PANTHER PTHR11751:SF388 45 372 5.3E-112 T 09-11-2016 CLOSPO_RS18890 54e20633198167eec50ad10e59f329ef 376 Gene3D G3DSA:3.90.1150.10 263 373 4.4E-18 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 PANTHER PTHR30055:SF27 1 204 1.1E-37 T 09-11-2016 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 Gene3D G3DSA:1.10.10.60 11 60 4.0E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 SUPERFAMILY SSF48498 108 194 1.16E-8 T 09-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 PANTHER PTHR30055 1 204 1.1E-37 T 09-11-2016 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.9E-8 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.9E-8 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 SUPERFAMILY SSF46689 8 65 1.44E-15 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.4E-14 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS16480 f016ee6793a03e76348b09330e5c01c6 210 Gene3D G3DSA:1.10.357.10 61 202 4.5E-35 T 09-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CLOSPO_RS16320 0caa2c6cf5b7c3f88abf645772a5d96e 636 PIRSF PIRSF005091 1 625 1.3E-184 T 09-11-2016 IPR012160 Lipoteichoic acid synthase-like KEGG: 00440+2.7.8.-|KEGG: 00513+2.7.8.-|KEGG: 00540+2.7.8.-|KEGG: 00564+2.7.8.-|KEGG: 00600+2.7.8.-|KEGG: 00770+2.7.8.-|UniPathway: UPA00556 CLOSPO_RS16320 0caa2c6cf5b7c3f88abf645772a5d96e 636 SUPERFAMILY SSF53649 252 614 1.64E-63 T 09-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CLOSPO_RS16320 0caa2c6cf5b7c3f88abf645772a5d96e 636 Gene3D G3DSA:3.40.720.10 254 555 8.8E-41 T 09-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CLOSPO_RS16320 0caa2c6cf5b7c3f88abf645772a5d96e 636 Pfam PF00884 Sulfatase 254 540 3.1E-39 T 09-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CLOSPO_RS16320 0caa2c6cf5b7c3f88abf645772a5d96e 636 PANTHER PTHR10342:SF225 225 567 3.2E-71 T 09-11-2016 CLOSPO_RS16320 0caa2c6cf5b7c3f88abf645772a5d96e 636 PANTHER PTHR10342 225 567 3.2E-71 T 09-11-2016 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 SMART SM00530 8 63 2.7E-15 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 SUPERFAMILY SSF47413 3 67 1.64E-17 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 Gene3D G3DSA:1.10.260.40 3 58 1.7E-21 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 Pfam PF01381 Helix-turn-helix 9 63 1.7E-14 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 PANTHER PTHR10245 1 181 1.0E-69 T 09-11-2016 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 Gene3D G3DSA:2.60.120.10 59 178 1.5E-25 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 PANTHER PTHR10245:SF53 1 181 1.0E-69 T 09-11-2016 CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 SUPERFAMILY SSF51182 56 181 2.31E-30 T 09-11-2016 IPR011051 RmlC-like cupin domain CLOSPO_RS12965 17b5c7cc4e5100cffd8cbf52ce36d597 181 Pfam PF07883 Cupin domain 108 175 1.4E-15 T 09-11-2016 IPR013096 Cupin 2, conserved barrel CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 PANTHER PTHR26402 2 227 7.7E-101 T 09-11-2016 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 Gene3D G3DSA:1.10.10.10 126 226 1.1E-32 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 SUPERFAMILY SSF46894 126 225 3.68E-29 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 SMART SM00862 149 225 6.8E-24 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 Pfam PF00072 Response regulator receiver domain 4 113 1.6E-29 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 Gene3D G3DSA:3.40.50.2300 3 125 9.5E-40 T 09-11-2016 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 SMART SM00448 2 113 2.3E-42 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 PANTHER PTHR26402:SF603 2 227 7.7E-101 T 09-11-2016 CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 SUPERFAMILY SSF52172 3 126 4.13E-41 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS12905 eca295255a85cacf4a0f739baefda5fe 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 7.4E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17405 ed7f6a7439a9414c8207bbed8ef87441 301 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 8 228 3.9E-50 T 09-11-2016 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CLOSPO_RS17405 ed7f6a7439a9414c8207bbed8ef87441 301 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 7 216 2.4E-31 T 09-11-2016 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CLOSPO_RS17405 ed7f6a7439a9414c8207bbed8ef87441 301 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 12 292 1.1E-63 T 09-11-2016 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap CLOSPO_RS14385 30d7ff617d59479094bf6ee6437a8299 276 Gene3D G3DSA:3.20.20.370 82 242 1.4E-40 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS14385 30d7ff617d59479094bf6ee6437a8299 276 SUPERFAMILY SSF88713 72 254 5.44E-49 T 09-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOSPO_RS14385 30d7ff617d59479094bf6ee6437a8299 276 PANTHER PTHR34216 48 270 3.1E-62 T 09-11-2016 CLOSPO_RS14385 30d7ff617d59479094bf6ee6437a8299 276 Pfam PF01522 Polysaccharide deacetylase 108 232 2.8E-34 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 Pfam PF13307 Helicase C-terminal domain 308 431 5.3E-22 T 09-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 PANTHER PTHR11472 15 431 1.5E-53 T 09-11-2016 CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 Gene3D G3DSA:3.40.50.300 296 386 1.0E-5 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 SUPERFAMILY SSF52540 82 152 1.03E-7 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 SUPERFAMILY SSF52540 298 387 1.03E-7 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 Pfam PF06733 DEAD_2 7 114 3.4E-12 T 09-11-2016 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS03695 cd75954fefc78df7a629f32cb01e7665 432 Pfam PF06777 Helical and beta-bridge domain 204 293 2.9E-8 T 09-11-2016 IPR010643 Helical and beta-bridge domain CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 SMART SM00530 6 61 2.6E-12 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 Gene3D G3DSA:1.25.40.10 131 301 9.6E-7 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 Pfam PF01381 Helix-turn-helix 7 59 4.5E-11 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 Gene3D G3DSA:1.10.260.40 1 63 2.3E-19 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 PANTHER PTHR10245 1 275 1.8E-27 T 09-11-2016 CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 PANTHER PTHR10245:SF46 1 275 1.8E-27 T 09-11-2016 CLOSPO_RS16915 2866b3211dfba5702af8b7b5e2ccf781 349 SUPERFAMILY SSF47413 1 67 5.14E-16 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 Gene3D G3DSA:3.40.190.10 8 110 6.7E-40 T 09-11-2016 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 6.6E-40 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 6.6E-40 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 6.6E-40 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 6.6E-40 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 6.6E-40 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 7 295 34.186 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 Gene3D G3DSA:3.40.190.10 111 200 8.6E-38 T 09-11-2016 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 SUPERFAMILY SSF54782 220 294 5.23E-18 T 09-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 2.7E-14 T 09-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 Gene3D G3DSA:3.30.160.40 222 294 1.1E-15 T 09-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 9 211 5.5E-71 T 09-11-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PANTHER PTHR11557 5 295 2.3E-123 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 SUPERFAMILY SSF53850 7 210 2.39E-72 T 09-11-2016 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 PIRSF PIRSF001438 3 295 1.3E-104 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18010 86cb804faef7464fa6fa15ac1e90a31a 295 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 9 294 6.2E-100 T 09-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 Gene3D G3DSA:1.20.1560.10 8 315 6.2E-65 T 09-11-2016 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 SUPERFAMILY SSF52540 330 565 1.09E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 Pfam PF00664 ABC transporter transmembrane region 21 289 6.2E-48 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 Pfam PF00005 ABC transporter 351 497 6.2E-32 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 SUPERFAMILY SSF90123 8 317 9.94E-65 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 Gene3D G3DSA:3.40.50.300 333 565 1.5E-64 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 PANTHER PTHR24221 2 565 5.8E-158 T 09-11-2016 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16255 35d284d0d567c445c53b22b1e59ca526 570 SMART SM00382 359 543 5.0E-10 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 SUPERFAMILY SSF89372 70 269 6.41E-46 T 09-11-2016 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Pfam PF03984 Repeat of unknown function (DUF346) 276 310 2.5E-5 T 09-11-2016 IPR007132 Protein of unknown function DUF346 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Pfam PF03984 Repeat of unknown function (DUF346) 97 131 2.4E-5 T 09-11-2016 IPR007132 Protein of unknown function DUF346 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Pfam PF03984 Repeat of unknown function (DUF346) 187 220 9.5E-8 T 09-11-2016 IPR007132 Protein of unknown function DUF346 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Pfam PF03984 Repeat of unknown function (DUF346) 231 266 1.4E-8 T 09-11-2016 IPR007132 Protein of unknown function DUF346 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Pfam PF03984 Repeat of unknown function (DUF346) 142 175 1.8E-8 T 09-11-2016 IPR007132 Protein of unknown function DUF346 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Gene3D G3DSA:2.120.10.70 127 335 2.8E-67 T 09-11-2016 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 Gene3D G3DSA:2.120.10.70 57 126 2.5E-15 T 09-11-2016 CLOSPO_RS12930 a8fd8a335e957addc9203cbf1ca17944 336 SUPERFAMILY SSF89372 270 335 1.96E-11 T 09-11-2016 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 SUPERFAMILY SSF101386 228 328 7.69E-25 T 09-11-2016 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 PANTHER PTHR30522 1 481 6.2E-170 T 09-11-2016 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 205 1.7E-28 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 SUPERFAMILY SSF101386 360 453 2.06E-25 T 09-11-2016 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 Gene3D G3DSA:3.40.1010.10 1 117 1.1E-14 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 PANTHER PTHR30522:SF0 1 481 6.2E-170 T 09-11-2016 IPR011551 NTP pyrophosphohydrolase MazG CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 TIGRFAM TIGR00444 mazG: MazG family protein 235 479 8.2E-95 T 09-11-2016 IPR011551 NTP pyrophosphohydrolase MazG CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 SUPERFAMILY SSF53790 1 253 1.06E-33 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 Gene3D G3DSA:1.10.287.1080 356 444 8.6E-18 T 09-11-2016 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 Gene3D G3DSA:1.10.287.1080 222 296 1.0E-9 T 09-11-2016 CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 PIRSF PIRSF002845 1 481 2.2E-225 T 09-11-2016 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 251 324 1.4E-29 T 09-11-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CLOSPO_RS15190 d2173fea3fc20dd2ba3d21d610740cc3 481 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 387 448 1.9E-8 T 09-11-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 PANTHER PTHR11776:SF9 49 265 2.2E-109 T 09-11-2016 CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 15 73 2.0E-20 T 09-11-2016 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 Gene3D G3DSA:3.40.50.2020 84 263 1.5E-48 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 263 6.5E-110 T 09-11-2016 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 Gene3D G3DSA:1.10.10.10 3 73 1.6E-29 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 SUPERFAMILY SSF53271 93 254 4.26E-36 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 PANTHER PTHR11776 49 265 2.2E-109 T 09-11-2016 CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 Pfam PF00156 Phosphoribosyl transferase domain 112 261 1.0E-20 T 09-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 Pfam PF09182 Bacterial purine repressor, N-terminal 6 73 2.1E-29 T 09-11-2016 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CLOSPO_RS15130 e919634db8a4f638b6941edf3f5cff60 271 SUPERFAMILY SSF46785 3 73 2.18E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS12640 c12ae67f7c4c9755231ae881a574d56c 149 Gene3D G3DSA:3.30.420.10 2 146 2.3E-56 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS12640 c12ae67f7c4c9755231ae881a574d56c 149 PANTHER PTHR10642 4 146 9.8E-53 T 09-11-2016 CLOSPO_RS12640 c12ae67f7c4c9755231ae881a574d56c 149 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 25.172 T 09-11-2016 IPR022892 Ribonuclease H GO:0004523 CLOSPO_RS12640 c12ae67f7c4c9755231ae881a574d56c 149 SUPERFAMILY SSF53098 1 145 2.4E-53 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS12640 c12ae67f7c4c9755231ae881a574d56c 149 Pfam PF00075 RNase H 2 144 6.1E-45 T 09-11-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 Gene3D G3DSA:1.10.10.60 1 57 1.8E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 5.6E-5 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 5.6E-5 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 PANTHER PTHR36444 52 289 7.2E-34 T 09-11-2016 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 PANTHER PTHR36444:SF2 52 289 7.2E-34 T 09-11-2016 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 SUPERFAMILY SSF55136 134 289 3.66E-27 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 SMART SM00871 132 289 3.4E-32 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 Gene3D G3DSA:1.10.10.60 58 106 5.0E-21 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 Gene3D G3DSA:3.20.80.10 130 289 1.3E-39 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 SUPERFAMILY SSF46689 57 108 4.21E-13 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 Pfam PF12833 Helix-turn-helix domain 28 105 1.1E-20 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 SUPERFAMILY SSF46689 5 55 1.08E-9 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 Pfam PF14526 Integron-associated effector binding protein 136 288 2.5E-31 T 09-11-2016 IPR029441 Integron-associated effector binding protein CLOSPO_RS17820 f9190c3f28d153957557029bcb042030 289 SMART SM00342 21 104 8.2E-29 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS14740 82e4cf9b3f04d942c4b00ce029862b6d 269 Pfam PF03618 Kinase/pyrophosphorylase 4 260 1.5E-89 T 09-11-2016 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CLOSPO_RS14740 82e4cf9b3f04d942c4b00ce029862b6d 269 PANTHER PTHR31756:SF3 1 269 4.6E-112 T 09-11-2016 CLOSPO_RS14740 82e4cf9b3f04d942c4b00ce029862b6d 269 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 2 266 57.379 T 09-11-2016 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CLOSPO_RS14740 82e4cf9b3f04d942c4b00ce029862b6d 269 PANTHER PTHR31756 1 269 4.6E-112 T 09-11-2016 CLOSPO_RS08755 1001586689f96416157b37275410edbf 127 PANTHER PTHR11136:SF0 1 105 5.1E-48 T 09-11-2016 CLOSPO_RS08755 1001586689f96416157b37275410edbf 127 SUPERFAMILY SSF53623 1 112 1.83E-40 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS08755 1001586689f96416157b37275410edbf 127 Gene3D G3DSA:3.40.1190.10 1 126 1.4E-38 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS08755 1001586689f96416157b37275410edbf 127 PANTHER PTHR11136 1 105 5.1E-48 T 09-11-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 CLOSPO_RS08755 1001586689f96416157b37275410edbf 127 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 23 38 - T 09-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 CLOSPO_RS08755 1001586689f96416157b37275410edbf 127 Pfam PF08245 Mur ligase middle domain 10 119 1.9E-9 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 Pfam PF02743 Cache domain 22 263 7.7E-36 T 09-11-2016 IPR033479 Double Cache domain 1 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 PANTHER PTHR32089 6 433 1.1E-208 T 09-11-2016 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 SUPERFAMILY SSF58104 330 431 5.49E-8 T 09-11-2016 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 Gene3D G3DSA:3.30.450.20 138 275 1.9E-30 T 09-11-2016 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 SMART SM00304 300 355 2.5E-6 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 SUPERFAMILY SSF103190 55 180 1.84E-8 T 09-11-2016 IPR029151 Periplasmic sensor domain-like CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 PANTHER PTHR32089:SF36 6 433 1.1E-208 T 09-11-2016 CLOSPO_RS10695 16410cefaff7a51e906c9e5dedbcac07 433 Pfam PF00672 HAMP domain 281 351 1.8E-9 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 408 3.1E-129 T 09-11-2016 IPR008135 Competence-induced protein CinA CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 SMART SM00852 4 171 6.7E-42 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 Gene3D G3DSA:3.90.950.20 248 408 6.0E-58 T 09-11-2016 IPR008136 CinA, C-terminal CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 261 408 1.1E-44 T 09-11-2016 IPR008136 CinA, C-terminal CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 SUPERFAMILY SSF53218 1 204 1.96E-42 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 165 3.5E-31 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 PIRSF PIRSF006728 1 409 3.3E-160 T 09-11-2016 IPR008135 Competence-induced protein CinA CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 Pfam PF00994 Probable molybdopterin binding domain 5 168 4.6E-36 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 409 173.844 T 09-11-2016 IPR008135 Competence-induced protein CinA CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 Pfam PF02464 Competence-damaged protein 255 407 7.5E-57 T 09-11-2016 IPR008136 CinA, C-terminal CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 SUPERFAMILY SSF142433 249 408 2.75E-55 T 09-11-2016 IPR008136 CinA, C-terminal CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 Gene3D G3DSA:3.40.980.10 1 208 1.6E-38 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 PANTHER PTHR13939 1 409 1.5E-206 T 09-11-2016 CLOSPO_RS13650 cd6f3dd6d774b5bb74c1b2e0adfd36c1 409 PANTHER PTHR13939:SF0 1 409 1.5E-206 T 09-11-2016 CLOSPO_RS16760 f0d402527127abc1ab23a3096b7ce6f4 191 Pfam PF03352 Methyladenine glycosylase 6 181 3.6E-76 T 09-11-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CLOSPO_RS16760 f0d402527127abc1ab23a3096b7ce6f4 191 SUPERFAMILY SSF48150 1 183 9.42E-76 T 09-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 CLOSPO_RS16760 f0d402527127abc1ab23a3096b7ce6f4 191 PANTHER PTHR30037:SF4 1 184 4.0E-96 T 09-11-2016 CLOSPO_RS16760 f0d402527127abc1ab23a3096b7ce6f4 191 PANTHER PTHR30037 1 184 4.0E-96 T 09-11-2016 CLOSPO_RS16760 f0d402527127abc1ab23a3096b7ce6f4 191 Gene3D G3DSA:1.10.340.30 1 182 2.7E-79 T 09-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 CLOSPO_RS18040 65834efd53f708d5d6547c25266569ab 231 Gene3D G3DSA:3.40.50.360 1 230 2.1E-30 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS18040 65834efd53f708d5d6547c25266569ab 231 SUPERFAMILY SSF52218 1 185 3.79E-24 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS18040 65834efd53f708d5d6547c25266569ab 231 PANTHER PTHR10204:SF38 1 213 2.2E-26 T 09-11-2016 CLOSPO_RS18040 65834efd53f708d5d6547c25266569ab 231 Pfam PF03358 NADPH-dependent FMN reductase 1 133 3.6E-12 T 09-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOSPO_RS18040 65834efd53f708d5d6547c25266569ab 231 PANTHER PTHR10204 1 213 2.2E-26 T 09-11-2016 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 277 41.078 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 10 109 9.7E-48 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 9 278 5.4E-126 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PANTHER PTHR22855:SF42 3 279 7.8E-115 T 09-11-2016 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PANTHER PTHR22855 3 279 7.8E-115 T 09-11-2016 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 Gene3D G3DSA:3.90.226.10 17 240 1.5E-49 T 09-11-2016 IPR029045 ClpP/crotonase-like domain CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 130 143 2.3E-44 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 158 167 2.3E-44 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 49 60 2.3E-44 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 74 92 2.3E-44 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 95 111 2.3E-44 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 114 127 2.3E-44 T 09-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 CLOSPO_RS14875 fc6efc84b854b5f8b4ef6a1f6879e0a9 279 SUPERFAMILY SSF52096 13 277 2.49E-93 T 09-11-2016 IPR029045 ClpP/crotonase-like domain CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 PANTHER PTHR26402:SF50 2 230 1.5E-99 T 09-11-2016 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 6.6E-25 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 SUPERFAMILY SSF46894 130 230 2.35E-27 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 Gene3D G3DSA:3.40.50.2300 2 128 4.0E-41 T 09-11-2016 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 SMART SM00448 2 112 2.8E-44 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 Gene3D G3DSA:1.10.10.10 130 230 4.3E-34 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 PANTHER PTHR26402 2 230 1.5E-99 T 09-11-2016 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 Pfam PF00072 Response regulator receiver domain 4 112 6.8E-31 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 SUPERFAMILY SSF52172 1 130 2.13E-42 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13310 f0b94065741b0a53911da3354c8b3c35 231 SMART SM00862 153 229 2.7E-24 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 SUPERFAMILY SSF51984 15 105 7.19E-14 T 09-11-2016 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 Gene3D G3DSA:3.90.190.20 315 455 5.5E-42 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 Gene3D G3DSA:3.40.1190.10 107 308 5.3E-48 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 PANTHER PTHR23135 7 458 2.3E-159 T 09-11-2016 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 SUPERFAMILY SSF53623 111 296 6.8E-43 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 Gene3D G3DSA:3.40.50.720 14 104 9.0E-14 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 15 458 31.427 T 09-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 SUPERFAMILY SSF53244 313 457 1.01E-36 T 09-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 PANTHER PTHR23135:SF2 7 458 2.3E-159 T 09-11-2016 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 Pfam PF08245 Mur ligase middle domain 122 294 6.8E-37 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS15320 25ae659d0be8fe2d60dd7d741bc5fdce 458 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 16 456 1.9E-111 T 09-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS17865 9c8a8daf8f15f2c75db8c76042273df9 111 Gene3D G3DSA:3.40.630.30 12 105 8.1E-15 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17865 9c8a8daf8f15f2c75db8c76042273df9 111 SUPERFAMILY SSF55729 12 105 1.26E-15 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17865 9c8a8daf8f15f2c75db8c76042273df9 111 Pfam PF13302 Acetyltransferase (GNAT) domain 15 82 2.0E-7 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS17865 9c8a8daf8f15f2c75db8c76042273df9 111 PANTHER PTHR39173 8 110 1.3E-36 T 09-11-2016 CLOSPO_RS18785 38299bbdf4c48577d06c2ca058e0708e 580 Gene3D G3DSA:3.80.10.10 297 451 4.9E-4 T 09-11-2016 IPR032675 Leucine-rich repeat domain, L domain-like CLOSPO_RS18785 38299bbdf4c48577d06c2ca058e0708e 580 Gene3D G3DSA:3.80.10.10 131 296 5.5E-4 T 09-11-2016 IPR032675 Leucine-rich repeat domain, L domain-like CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 Pfam PF07731 Multicopper oxidase 193 280 1.2E-18 T 09-11-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 Gene3D G3DSA:2.60.40.420 144 280 4.9E-33 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 SUPERFAMILY SSF49503 141 281 2.14E-29 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 PANTHER PTHR11709 18 263 2.1E-40 T 09-11-2016 CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 PANTHER PTHR11709:SF33 18 263 2.1E-40 T 09-11-2016 CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 Gene3D G3DSA:2.60.40.420 16 142 7.5E-33 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 SUPERFAMILY SSF49503 13 141 1.55E-34 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS18655 9e14bbec9c0ddfcd423a25c1bb55b686 294 Pfam PF07732 Multicopper oxidase 39 141 1.2E-29 T 09-11-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 CLOSPO_RS13470 7f867a25a3e3f4eb44bc8a0b02dd6b8f 136 SUPERFAMILY SSF55608 2 108 1.17E-13 T 09-11-2016 IPR027434 Homing endonuclease GO:0004519 CLOSPO_RS13470 7f867a25a3e3f4eb44bc8a0b02dd6b8f 136 Gene3D G3DSA:3.10.28.10 2 126 1.1E-23 T 09-11-2016 IPR027434 Homing endonuclease GO:0004519 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 264 43.809 T 09-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 Gene3D G3DSA:3.20.20.60 2 265 1.7E-119 T 09-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 SUPERFAMILY SSF51621 3 264 1.57E-108 T 09-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 PIRSF PIRSF000388 1 267 1.7E-112 T 09-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 4 265 3.0E-106 T 09-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 260 5.6E-117 T 09-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 CLOSPO_RS15470 81e1bc136a498c228819d84462cc2043 275 PANTHER PTHR20881 2 275 1.5E-161 T 09-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 Pfam PF02195 ParB-like nuclease domain 7 95 1.4E-24 T 09-11-2016 IPR003115 ParB/Sulfiredoxin CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 5 258 5.7E-95 T 09-11-2016 IPR023705 Nucleoid occlusion protein CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 PANTHER PTHR33375 2 257 1.5E-85 T 09-11-2016 CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 SUPERFAMILY SSF110849 5 134 2.41E-33 T 09-11-2016 IPR003115 ParB/Sulfiredoxin CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 2 181 3.1E-53 T 09-11-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 Gene3D G3DSA:3.90.1530.10 2 102 2.1E-39 T 09-11-2016 CLOSPO_RS14590 7713054c42d6774e5b17b80f3656d69a 259 SMART SM00470 6 96 5.8E-31 T 09-11-2016 IPR003115 ParB/Sulfiredoxin CLOSPO_RS18370 4e962a6298ac16c4971788ebd34c7d4c 335 Gene3D G3DSA:3.20.20.140 3 330 2.7E-107 T 09-11-2016 CLOSPO_RS18370 4e962a6298ac16c4971788ebd34c7d4c 335 Pfam PF00962 Adenosine/AMP deaminase 6 325 5.0E-73 T 09-11-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 CLOSPO_RS18370 4e962a6298ac16c4971788ebd34c7d4c 335 SUPERFAMILY SSF51556 4 331 1.9E-91 T 09-11-2016 IPR032466 Metal-dependent hydrolase CLOSPO_RS18370 4e962a6298ac16c4971788ebd34c7d4c 335 Hamap MF_00540 Adenosine deaminase [add]. 1 331 59.083 T 09-11-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CLOSPO_RS18370 4e962a6298ac16c4971788ebd34c7d4c 335 PANTHER PTHR11409 3 333 1.2E-114 T 09-11-2016 CLOSPO_RS18370 4e962a6298ac16c4971788ebd34c7d4c 335 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 326 9.4E-95 T 09-11-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 CLOSPO_RS16685 6bd45d305ddd21319e7ffe1abb83d684 236 Pfam PF02698 DUF218 domain 63 182 1.7E-25 T 09-11-2016 IPR003848 Domain of unknown function DUF218 CLOSPO_RS16685 6bd45d305ddd21319e7ffe1abb83d684 236 PANTHER PTHR30336:SF0 16 221 7.8E-79 T 09-11-2016 CLOSPO_RS16685 6bd45d305ddd21319e7ffe1abb83d684 236 PANTHER PTHR30336 16 221 7.8E-79 T 09-11-2016 CLOSPO_RS16685 6bd45d305ddd21319e7ffe1abb83d684 236 Gene3D G3DSA:3.40.50.620 56 182 1.2E-15 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS15800 8facec0cec9bb4a097c5f3a179f7c5bd 219 PANTHER PTHR35864 1 219 2.3E-38 T 09-11-2016 CLOSPO_RS15800 8facec0cec9bb4a097c5f3a179f7c5bd 219 Pfam PF02163 Peptidase family M50 135 188 1.5E-7 T 09-11-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 SMART SM01061 1 59 2.4E-25 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 SUPERFAMILY SSF63520 172 275 8.37E-25 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 Gene3D G3DSA:1.10.1790.10 65 163 3.0E-30 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 Gene3D G3DSA:1.10.1790.10 170 277 2.7E-30 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 SUPERFAMILY SSF63520 57 166 1.31E-29 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 PANTHER PTHR30185:SF2 1 278 1.7E-133 T 09-11-2016 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 SUPERFAMILY SSF50151 1 51 1.12E-16 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 Pfam PF03123 CAT RNA binding domain 1 56 1.8E-20 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 PANTHER PTHR30185 1 278 1.7E-133 T 09-11-2016 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 Gene3D G3DSA:2.30.24.10 1 53 1.8E-20 T 09-11-2016 IPR004341 CAT RNA-binding domain GO:0003723 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 Pfam PF00874 PRD domain 76 163 2.7E-23 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS16725 fadf9dc229b73dd9336c404ac38e6dd1 278 Pfam PF00874 PRD domain 181 274 2.7E-19 T 09-11-2016 IPR011608 PRD domain GO:0006355 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PANTHER PTHR12383:SF14 4 75 3.2E-53 T 09-11-2016 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PANTHER PTHR12383:SF14 107 202 3.2E-53 T 09-11-2016 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 196 7.2E-45 T 09-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 Gene3D G3DSA:2.10.109.10 155 201 1.0E-34 T 09-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 Gene3D G3DSA:2.10.109.10 27 119 1.0E-34 T 09-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 ProSitePatterns PS00760 Signal peptidases I lysine active site. 111 123 - T 09-11-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 SUPERFAMILY SSF51306 104 201 2.96E-43 T 09-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 SUPERFAMILY SSF51306 31 76 2.96E-43 T 09-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 Pfam PF00717 Peptidase S24-like 37 133 1.8E-10 T 09-11-2016 IPR019759 Peptidase S24/S26A/S26B CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PANTHER PTHR12383 107 202 3.2E-53 T 09-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PANTHER PTHR12383 4 75 3.2E-53 T 09-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 ProSitePatterns PS00761 Signal peptidases I signature 3. 160 173 - T 09-11-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 155 174 1.2E-15 T 09-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 1.2E-15 T 09-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOSPO_RS16205 10424ce7f6ab5a0bc5e74e018094e14a 202 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 109 121 1.2E-15 T 09-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOSPO_RS14215 bf5f621ac91b759c0eb3df290c2d390f 355 SUPERFAMILY SSF53448 2 278 9.47E-61 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS14215 bf5f621ac91b759c0eb3df290c2d390f 355 Pfam PF00483 Nucleotidyl transferase 4 278 1.2E-47 T 09-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 CLOSPO_RS14215 bf5f621ac91b759c0eb3df290c2d390f 355 SUPERFAMILY SSF159283 285 346 7.45E-15 T 09-11-2016 CLOSPO_RS14215 bf5f621ac91b759c0eb3df290c2d390f 355 PANTHER PTHR12526 152 279 1.6E-41 T 09-11-2016 CLOSPO_RS14215 bf5f621ac91b759c0eb3df290c2d390f 355 Gene3D G3DSA:3.90.550.10 3 270 7.0E-81 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 PANTHER PTHR35791:SF1 387 501 5.0E-65 T 09-11-2016 CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 PANTHER PTHR35791:SF1 195 323 5.0E-65 T 09-11-2016 CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 PANTHER PTHR35791:SF1 1 163 5.0E-65 T 09-11-2016 CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 PANTHER PTHR35791 195 323 5.0E-65 T 09-11-2016 CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 PANTHER PTHR35791 387 501 5.0E-65 T 09-11-2016 CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 Pfam PF04286 Protein of unknown function (DUF445) 8 501 7.4E-66 T 09-11-2016 IPR007383 Protein of unknown function DUF445 CLOSPO_RS14345 ceb87cdbcafd0420ef1c387673001900 501 PANTHER PTHR35791 1 163 5.0E-65 T 09-11-2016 CLOSPO_RS13425 c4b51dc24582dee84b4ab20a5f59cb09 219 SUPERFAMILY SSF51182 81 199 4.18E-26 T 09-11-2016 IPR011051 RmlC-like cupin domain CLOSPO_RS13425 c4b51dc24582dee84b4ab20a5f59cb09 219 Gene3D G3DSA:2.60.120.10 94 218 4.8E-47 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS13425 c4b51dc24582dee84b4ab20a5f59cb09 219 Pfam PF07883 Cupin domain 119 194 5.4E-14 T 09-11-2016 IPR013096 Cupin 2, conserved barrel CLOSPO_RS17510 2a44ffa36de2d69c8f7335d203709304 248 PANTHER PTHR34148 1 248 6.7E-61 T 09-11-2016 CLOSPO_RS17510 2a44ffa36de2d69c8f7335d203709304 248 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 8 244 1.2E-45 T 09-11-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 CLOSPO_RS17510 2a44ffa36de2d69c8f7335d203709304 248 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 248 42.114 T 09-11-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 CLOSPO_RS17510 2a44ffa36de2d69c8f7335d203709304 248 PANTHER PTHR34148:SF1 1 248 6.7E-61 T 09-11-2016 CLOSPO_RS17510 2a44ffa36de2d69c8f7335d203709304 248 Pfam PF02654 Cobalamin-5-phosphate synthase 12 243 1.1E-53 T 09-11-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 CLOSPO_RS15705 faae49025b08dc9627da229439d40515 283 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 215 4.9E-58 T 09-11-2016 IPR003740 Uncharacterised membrane protein YitT CLOSPO_RS15705 faae49025b08dc9627da229439d40515 283 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 275 1.2E-17 T 09-11-2016 IPR019264 Domain of unknown function DUF2179 CLOSPO_RS15705 faae49025b08dc9627da229439d40515 283 PANTHER PTHR33545:SF7 2 279 7.0E-141 T 09-11-2016 CLOSPO_RS15705 faae49025b08dc9627da229439d40515 283 PIRSF PIRSF006483 1 283 9.3E-86 T 09-11-2016 IPR003740 Uncharacterised membrane protein YitT CLOSPO_RS15705 faae49025b08dc9627da229439d40515 283 PANTHER PTHR33545 2 279 7.0E-141 T 09-11-2016 CLOSPO_RS14725 fb0eace32595429f80a4658f6c99e213 249 PANTHER PTHR31727 4 229 1.9E-66 T 09-11-2016 CLOSPO_RS14725 fb0eace32595429f80a4658f6c99e213 249 SUPERFAMILY SSF54637 3 140 1.04E-40 T 09-11-2016 IPR029069 HotDog domain CLOSPO_RS14725 fb0eace32595429f80a4658f6c99e213 249 Gene3D G3DSA:3.10.129.10 147 247 2.2E-24 T 09-11-2016 IPR029069 HotDog domain CLOSPO_RS14725 fb0eace32595429f80a4658f6c99e213 249 Pfam PF01643 Acyl-ACP thioesterase 6 248 4.7E-67 T 09-11-2016 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 CLOSPO_RS14725 fb0eace32595429f80a4658f6c99e213 249 SUPERFAMILY SSF54637 145 248 2.31E-25 T 09-11-2016 IPR029069 HotDog domain CLOSPO_RS14725 fb0eace32595429f80a4658f6c99e213 249 Gene3D G3DSA:3.10.129.10 5 141 1.3E-33 T 09-11-2016 IPR029069 HotDog domain CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 343 9.1E-69 T 09-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 SUPERFAMILY SSF50615 3 76 1.1E-25 T 09-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 Hamap MF_01347 ATP synthase subunit beta [atpB]. 2 461 58.563 T 09-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 SMART SM00382 143 382 4.1E-6 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 SUPERFAMILY SSF47917 346 461 3.14E-52 T 09-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 Gene3D G3DSA:1.10.1140.10 346 461 1.4E-50 T 09-11-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 PANTHER PTHR15184:SF8 3 462 0.0 T 09-11-2016 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 74 1.3E-21 T 09-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 334 343 - T 09-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 Gene3D G3DSA:2.40.10.170 3 76 2.1E-31 T 09-11-2016 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 SUPERFAMILY SSF52540 78 348 1.53E-95 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 Gene3D G3DSA:3.40.50.300 77 345 1.8E-112 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 4 461 1.8E-254 T 09-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CLOSPO_RS13945 102a23ca6b6419b7a5fda27afbd59f8e 462 PANTHER PTHR15184 3 462 0.0 T 09-11-2016 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 PANTHER PTHR22594:SF10 1 429 4.1E-172 T 09-11-2016 IPR004523 Aspartyl-tRNA synthetase, archaeal-type GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 SUPERFAMILY SSF50249 5 98 1.89E-20 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 1.1E-18 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 1.1E-18 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 1.1E-18 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 1.1E-18 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 14 429 2.2E-132 T 09-11-2016 IPR004523 Aspartyl-tRNA synthetase, archaeal-type GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 Pfam PF01336 OB-fold nucleic acid binding domain 18 90 6.1E-13 T 09-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 SUPERFAMILY SSF55681 98 426 5.88E-80 T 09-11-2016 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 Gene3D G3DSA:3.30.930.10 103 427 8.4E-93 T 09-11-2016 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 Gene3D G3DSA:2.40.50.140 4 98 3.4E-23 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 419 1.5E-77 T 09-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18535 142d528d121512ead64937c64106769c 429 PANTHER PTHR22594 1 429 4.1E-172 T 09-11-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 Gene3D G3DSA:3.40.50.620 1 174 5.7E-78 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 73 1.2E-9 T 09-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 1.3E-106 T 09-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 PANTHER PTHR21299:SF1 1 276 1.4E-140 T 09-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 SUPERFAMILY SSF52374 1 279 2.95E-107 T 09-11-2016 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 277 9.0E-109 T 09-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 PANTHER PTHR21299 1 276 1.4E-140 T 09-11-2016 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 Gene3D G3DSA:3.30.1300.10 178 277 1.8E-30 T 09-11-2016 CLOSPO_RS15465 5ccfb1690a3e93dafac8b084a6a418f1 281 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 40.175 T 09-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Pfam PF00403 Heavy-metal-associated domain 9 61 5.9E-11 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF81653 246 341 3.27E-22 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PANTHER PTHR24093 2 743 0.0 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00941 Cadmium-transporting ATPase signature 309 325 6.2E-8 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00941 Cadmium-transporting ATPase signature 228 248 6.2E-8 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00941 Cadmium-transporting ATPase signature 7 16 6.2E-8 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00941 Cadmium-transporting ATPase signature 328 342 6.2E-8 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Pfam PF00122 E1-E2 ATPase 215 436 1.4E-61 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF81665 689 726 1.31E-10 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF81665 344 439 1.31E-10 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF81665 194 247 1.31E-10 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF55008 2 72 2.09E-10 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Pfam PF00702 haloacid dehalogenase-like hydrolase 442 653 1.0E-32 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Gene3D G3DSA:2.70.150.10 194 344 1.2E-24 T 09-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF56784 443 463 1.24E-55 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 SUPERFAMILY SSF56784 501 740 1.24E-55 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Gene3D G3DSA:3.40.1110.10 467 560 6.7E-12 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 194 744 2.3E-152 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 214 719 2.6E-71 T 09-11-2016 IPR001757 P-type ATPase GO:0016021 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Gene3D G3DSA:3.30.70.100 4 75 4.4E-12 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Gene3D G3DSA:3.40.1110.10 436 466 6.0E-4 T 09-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 447 453 - T 09-11-2016 IPR018303 P-type ATPase, phosphorylation site CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 Gene3D G3DSA:3.40.50.1000 561 709 1.8E-42 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 658 7.9E-19 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 675 7.9E-19 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 293 307 7.9E-19 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 583 593 7.9E-19 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 445 459 7.9E-19 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 PANTHER PTHR24093:SF210 2 743 0.0 T 09-11-2016 CLOSPO_RS15715 7d1c72bcb56b33f337054c0c2f2bba45 744 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 194 741 2.5E-169 T 09-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 PANTHER PTHR40447 1 342 2.1E-133 T 09-11-2016 CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 Gene3D G3DSA:1.10.1060.10 222 333 1.4E-11 T 09-11-2016 CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 SUPERFAMILY SSF46548 223 330 3.66E-15 T 09-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 Pfam PF17179 4Fe-4S dicluster domain 224 320 3.2E-34 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 TIGRFAM TIGR02910 sulfite_red_A: sulfite reductase, subunit A 1 336 9.8E-188 T 09-11-2016 IPR014259 Sulphite reductase, subunit A UniPathway: UPA00370 CLOSPO_RS18195 cbe86891f43751273bcdc67c957febda 342 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 225 236 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS13965 3d227d5dfc6b550384241f49f36135e0 159 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 157 12.553 T 09-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13965 3d227d5dfc6b550384241f49f36135e0 159 PANTHER PTHR33445 1 158 6.5E-35 T 09-11-2016 CLOSPO_RS13965 3d227d5dfc6b550384241f49f36135e0 159 Pfam PF00430 ATP synthase B/B' CF(0) 9 135 2.2E-19 T 09-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13965 3d227d5dfc6b550384241f49f36135e0 159 SUPERFAMILY SSF81573 65 122 5.1E-7 T 09-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain CLOSPO_RS13965 3d227d5dfc6b550384241f49f36135e0 159 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 12 157 1.5E-28 T 09-11-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13965 3d227d5dfc6b550384241f49f36135e0 159 Gene3D G3DSA:1.20.5.620 65 122 1.1E-5 T 09-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain CLOSPO_RS16995 a3cad8f53085e4f4246fba476c0743e4 146 Gene3D G3DSA:3.40.630.30 1 139 4.9E-20 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16995 a3cad8f53085e4f4246fba476c0743e4 146 Pfam PF00583 Acetyltransferase (GNAT) family 53 136 2.5E-9 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS16995 a3cad8f53085e4f4246fba476c0743e4 146 SUPERFAMILY SSF55729 1 141 2.66E-21 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS12935 f14c09425aba7a47414e155f6d73c7fb 156 Pfam PF11385 Protein of unknown function (DUF3189) 3 148 2.1E-55 T 09-11-2016 IPR021525 Protein of unknown function DUF3189 CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 SUPERFAMILY SSF53067 227 356 5.34E-25 T 09-11-2016 CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 PANTHER PTHR32329:SF4 1 357 2.8E-235 T 09-11-2016 CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 Gene3D G3DSA:3.30.420.40 5 140 1.3E-46 T 09-11-2016 CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 228 357 3.8E-17 T 09-11-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 161 2.4E-14 T 09-11-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 Gene3D G3DSA:3.30.420.40 225 357 1.3E-36 T 09-11-2016 CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 PANTHER PTHR32329 1 357 2.8E-235 T 09-11-2016 CLOSPO_RS08665 f347b6332314125b3995df950ebfdf68 357 SUPERFAMILY SSF53067 4 162 1.77E-37 T 09-11-2016 CLOSPO_RS18850 60caca0128dd4c0f1d29f8f0e6fb2f00 112 PANTHER PTHR30041:SF3 1 111 1.8E-28 T 09-11-2016 CLOSPO_RS18850 60caca0128dd4c0f1d29f8f0e6fb2f00 112 PANTHER PTHR30041 1 111 1.8E-28 T 09-11-2016 CLOSPO_RS18850 60caca0128dd4c0f1d29f8f0e6fb2f00 112 Gene3D G3DSA:3.40.30.10 2 111 5.1E-32 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS18850 60caca0128dd4c0f1d29f8f0e6fb2f00 112 Pfam PF03960 ArsC family 34 110 6.9E-9 T 09-11-2016 IPR006660 Arsenate reductase-like CLOSPO_RS18850 60caca0128dd4c0f1d29f8f0e6fb2f00 112 SUPERFAMILY SSF52833 2 111 2.08E-25 T 09-11-2016 IPR012336 Thioredoxin-like fold CLOSPO_RS00825 697310873cdad1945477b48cef4e9c9f 155 SUPERFAMILY SSF53807 15 146 1.1E-16 T 09-11-2016 CLOSPO_RS00825 697310873cdad1945477b48cef4e9c9f 155 Pfam PF01497 Periplasmic binding protein 12 144 8.5E-11 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS00825 697310873cdad1945477b48cef4e9c9f 155 PANTHER PTHR30535:SF5 22 155 3.7E-20 T 09-11-2016 CLOSPO_RS00825 697310873cdad1945477b48cef4e9c9f 155 PANTHER PTHR30535 22 155 3.7E-20 T 09-11-2016 CLOSPO_RS00825 697310873cdad1945477b48cef4e9c9f 155 Gene3D G3DSA:3.40.50.1980 54 149 4.0E-12 T 09-11-2016 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 SUPERFAMILY SSF55469 227 317 6.28E-21 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 SUPERFAMILY SSF55469 121 200 6.28E-21 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 PANTHER PTHR23026 97 150 2.0E-52 T 09-11-2016 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 PANTHER PTHR23026 172 318 2.0E-52 T 09-11-2016 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 Gene3D G3DSA:3.40.109.10 120 318 2.7E-30 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 Pfam PF00881 Nitroreductase family 124 314 1.2E-25 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 139 314 1.4E-59 T 09-11-2016 IPR020051 SagB-type dehydrogenase domain CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 PANTHER PTHR23026:SF61 172 318 2.0E-52 T 09-11-2016 CLOSPO_RS15760 0d9d1cbd6da3feb53e7197e3ca57481e 318 PANTHER PTHR23026:SF61 97 150 2.0E-52 T 09-11-2016 CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 Pfam PF03167 Uracil DNA glycosylase superfamily 28 175 1.4E-44 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 Gene3D G3DSA:3.40.470.10 3 184 3.3E-68 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 SUPERFAMILY SSF52141 4 183 3.11E-60 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 PANTHER PTHR33693 3 189 6.9E-75 T 09-11-2016 CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 SMART SM00986 28 175 1.7E-37 T 09-11-2016 IPR005122 Uracil-DNA glycosylase-like CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 PANTHER PTHR33693:SF1 3 189 6.9E-75 T 09-11-2016 CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 SMART SM00987 28 175 1.7E-37 T 09-11-2016 CLOSPO_RS14360 daceac6cf120d4fd04dffc065099c19d 190 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 178 2.9E-56 T 09-11-2016 IPR005273 Uracil-DNA glycosylase, family 4 domain CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 Gene3D G3DSA:3.40.50.2300 2 127 5.6E-37 T 09-11-2016 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 SUPERFAMILY SSF52172 3 125 1.57E-37 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 2.3E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 SMART SM00448 2 112 1.1E-37 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 PANTHER PTHR26402 2 237 8.4E-90 T 09-11-2016 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 Gene3D G3DSA:1.10.10.10 137 236 2.1E-29 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 SUPERFAMILY SSF46894 132 235 1.08E-27 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 PANTHER PTHR26402:SF596 2 237 8.4E-90 T 09-11-2016 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 Pfam PF00072 Response regulator receiver domain 4 113 6.6E-26 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS17340 a1118787716b198602becc4141fb7ccd 237 SMART SM00862 157 235 2.6E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 PANTHER PTHR13774:SF15 1 304 5.0E-127 T 09-11-2016 CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 PIRSF PIRSF016184 1 303 8.0E-81 T 09-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 Gene3D G3DSA:3.10.310.10 134 292 1.1E-43 T 09-11-2016 CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 SUPERFAMILY SSF54506 4 301 2.51E-63 T 09-11-2016 CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 299 1.4E-71 T 09-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 Pfam PF02567 Phenazine biosynthesis-like protein 9 296 4.2E-63 T 09-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 Gene3D G3DSA:3.10.310.10 4 133 3.8E-39 T 09-11-2016 CLOSPO_RS17650 4657ae9ca3f68eacc047af71974318d2 306 PANTHER PTHR13774 1 304 5.0E-127 T 09-11-2016 CLOSPO_RS14860 145d9257c21f74223e02ed1f9c2d6b68 144 Gene3D G3DSA:3.10.129.10 4 143 9.0E-55 T 09-11-2016 IPR029069 HotDog domain CLOSPO_RS14860 145d9257c21f74223e02ed1f9c2d6b68 144 Pfam PF07977 FabA-like domain 14 137 7.4E-35 T 09-11-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CLOSPO_RS14860 145d9257c21f74223e02ed1f9c2d6b68 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 144 33.601 T 09-11-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CLOSPO_RS14860 145d9257c21f74223e02ed1f9c2d6b68 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 5 141 6.1E-57 T 09-11-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CLOSPO_RS14860 145d9257c21f74223e02ed1f9c2d6b68 144 SUPERFAMILY SSF54637 7 142 2.95E-44 T 09-11-2016 IPR029069 HotDog domain CLOSPO_RS14860 145d9257c21f74223e02ed1f9c2d6b68 144 PANTHER PTHR30272 1 144 2.3E-78 T 09-11-2016 CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 PANTHER PTHR24220:SF358 5 241 3.7E-126 T 09-11-2016 CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 239 5.7E-9 T 09-11-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 Pfam PF00005 ABC transporter 20 167 5.9E-33 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 Gene3D G3DSA:3.40.50.300 3 237 5.0E-70 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 PANTHER PTHR24220 5 241 3.7E-126 T 09-11-2016 CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 SUPERFAMILY SSF52540 3 239 8.52E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15620 7fc05d6e3236a328d57756234e8bcdb7 245 SMART SM00382 28 216 2.8E-10 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12165 d12bf4264026dd01599d960832efe98a 247 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 4 247 8.4E-104 T 09-11-2016 IPR014226 Sporulation integral membrane protein YlbJ CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 Gene3D G3DSA:3.30.420.40 94 258 1.1E-50 T 09-11-2016 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 Gene3D G3DSA:3.30.420.40 1 80 6.8E-4 T 09-11-2016 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 SUPERFAMILY SSF53067 123 257 3.37E-34 T 09-11-2016 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 253 7.4E-75 T 09-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 SUPERFAMILY SSF53067 1 121 7.45E-40 T 09-11-2016 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 Pfam PF03309 Type III pantothenate kinase 2 205 2.1E-73 T 09-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 PANTHER PTHR34265 1 257 5.4E-80 T 09-11-2016 CLOSPO_RS15285 19be598a8f48a967dfdfd391d49556c8 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 258 36.859 T 09-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 CLOSPO_RS18375 384744b687555691b119307171fcbd61 722 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 14 176 1.8E-47 T 09-11-2016 IPR017500 Phage infection protein, YhgE, N-terminal CLOSPO_RS18375 384744b687555691b119307171fcbd61 722 PANTHER PTHR30294:SF4 514 716 1.6E-94 T 09-11-2016 CLOSPO_RS18375 384744b687555691b119307171fcbd61 722 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 499 702 3.7E-43 T 09-11-2016 IPR017501 Phage infection protein, YhgE, C-terminal CLOSPO_RS18375 384744b687555691b119307171fcbd61 722 PANTHER PTHR30294 514 716 1.6E-94 T 09-11-2016 CLOSPO_RS18375 384744b687555691b119307171fcbd61 722 PANTHER PTHR30294 1 252 1.6E-94 T 09-11-2016 CLOSPO_RS18375 384744b687555691b119307171fcbd61 722 PANTHER PTHR30294:SF4 1 252 1.6E-94 T 09-11-2016 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 PANTHER PTHR32089 192 494 1.5E-53 T 09-11-2016 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 PANTHER PTHR32089:SF1 192 494 1.5E-53 T 09-11-2016 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 Gene3D G3DSA:1.10.287.950 242 440 3.6E-43 T 09-11-2016 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 SMART SM00283 224 485 2.8E-35 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 290 482 6.2E-37 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 351 380 2.3E-13 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 322 349 2.3E-13 T 09-11-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CLOSPO_RS13195 675a4037b9e4e9d87ef3107239aedc1b 498 SUPERFAMILY SSF58104 203 494 2.79E-52 T 09-11-2016 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 Pfam PF00936 BMC domain 148 213 8.7E-12 T 09-11-2016 IPR000249 Microcompartment protein, bacteria CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 Pfam PF00936 BMC domain 42 110 3.0E-10 T 09-11-2016 IPR000249 Microcompartment protein, bacteria CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 PANTHER PTHR40609:SF2 1 232 1.6E-125 T 09-11-2016 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 PIRSF PIRSF012290 1 232 1.5E-89 T 09-11-2016 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 SUPERFAMILY SSF143414 41 118 4.05E-7 T 09-11-2016 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 TIGRFAM TIGR04501 microcomp_PduB: microcompartment protein PduB 8 232 1.2E-118 T 09-11-2016 IPR030984 Microcompartment protein PduB GO:0005198 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 PANTHER PTHR40609 1 232 1.6E-125 T 09-11-2016 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 SUPERFAMILY SSF143414 147 216 1.96E-9 T 09-11-2016 CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 SMART SM00877 147 224 1.2E-9 T 09-11-2016 IPR000249 Microcompartment protein, bacteria CLOSPO_RS17810 f3930767a424fdf6d5c23c91eb2d3888 232 SMART SM00877 41 123 1.2E-9 T 09-11-2016 IPR000249 Microcompartment protein, bacteria CLOSPO_RS03460 f709d473c5d8f87311660484a082b305 336 Pfam PF00149 Calcineurin-like phosphoesterase 4 243 1.5E-13 T 09-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CLOSPO_RS03460 f709d473c5d8f87311660484a082b305 336 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 4 272 1.8E-54 T 09-11-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CLOSPO_RS03460 f709d473c5d8f87311660484a082b305 336 PANTHER PTHR30337 4 336 5.0E-102 T 09-11-2016 CLOSPO_RS03460 f709d473c5d8f87311660484a082b305 336 PANTHER PTHR30337:SF0 4 336 5.0E-102 T 09-11-2016 CLOSPO_RS03460 f709d473c5d8f87311660484a082b305 336 Gene3D G3DSA:3.60.21.10 4 289 1.0E-64 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS03460 f709d473c5d8f87311660484a082b305 336 SUPERFAMILY SSF56300 4 333 1.06E-53 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS14985 4c56440be8f866f61bee866ca9dc0f9d 179 PANTHER PTHR23026 1 179 3.0E-51 T 09-11-2016 CLOSPO_RS14985 4c56440be8f866f61bee866ca9dc0f9d 179 PANTHER PTHR23026:SF90 1 179 3.0E-51 T 09-11-2016 CLOSPO_RS14985 4c56440be8f866f61bee866ca9dc0f9d 179 Gene3D G3DSA:3.40.109.10 2 179 5.2E-58 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS14985 4c56440be8f866f61bee866ca9dc0f9d 179 Pfam PF00881 Nitroreductase family 5 157 3.6E-29 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS14985 4c56440be8f866f61bee866ca9dc0f9d 179 SUPERFAMILY SSF55469 2 179 1.31E-54 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS17605 4d009c521da22d36cc2fdbb98e4e3d8c 381 SUPERFAMILY SSF47413 5 69 4.9E-18 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17605 4d009c521da22d36cc2fdbb98e4e3d8c 381 Gene3D G3DSA:1.10.260.40 5 68 6.9E-22 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17605 4d009c521da22d36cc2fdbb98e4e3d8c 381 PANTHER PTHR10245:SF46 4 278 3.2E-75 T 09-11-2016 CLOSPO_RS17605 4d009c521da22d36cc2fdbb98e4e3d8c 381 Pfam PF01381 Helix-turn-helix 13 64 2.3E-15 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17605 4d009c521da22d36cc2fdbb98e4e3d8c 381 PANTHER PTHR10245 4 278 3.2E-75 T 09-11-2016 CLOSPO_RS17605 4d009c521da22d36cc2fdbb98e4e3d8c 381 SMART SM00530 9 64 5.2E-14 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS08265 9da80ab14de53d896805b88ad078e7e7 108 PANTHER PTHR11895 1 104 1.6E-31 T 09-11-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08265 9da80ab14de53d896805b88ad078e7e7 108 Pfam PF01425 Amidase 2 107 8.7E-21 T 09-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08265 9da80ab14de53d896805b88ad078e7e7 108 SUPERFAMILY SSF75304 1 107 1.24E-21 T 09-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08265 9da80ab14de53d896805b88ad078e7e7 108 Gene3D G3DSA:3.90.1300.10 2 106 1.3E-23 T 09-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08265 9da80ab14de53d896805b88ad078e7e7 108 PANTHER PTHR11895:SF7 1 104 1.6E-31 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 SUPERFAMILY SSF53850 43 302 1.67E-55 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 Gene3D G3DSA:3.40.190.10 264 300 2.3E-4 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 Gene3D G3DSA:3.40.190.10 2 139 2.3E-4 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 PANTHER PTHR30570:SF1 1 303 2.5E-71 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 PANTHER PTHR30570 1 303 2.5E-71 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 Gene3D G3DSA:3.40.190.10 140 263 3.3E-31 T 09-11-2016 CLOSPO_RS12735 c69c3b21a0895f2a945f8f6c4cc66cd4 303 Pfam PF12849 PBP superfamily domain 35 288 4.7E-28 T 09-11-2016 IPR024370 PBP domain CLOSPO_RS16960 fc17946b153c648c0494893e48f39149 484 Gene3D G3DSA:3.40.640.10 84 287 6.4E-33 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS16960 fc17946b153c648c0494893e48f39149 484 SUPERFAMILY SSF53383 21 483 8.54E-110 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS16960 fc17946b153c648c0494893e48f39149 484 Pfam PF02347 Glycine cleavage system P-protein 33 300 6.0E-14 T 09-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 CLOSPO_RS16960 fc17946b153c648c0494893e48f39149 484 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 6 484 58.893 T 09-11-2016 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CLOSPO_RS16960 fc17946b153c648c0494893e48f39149 484 PANTHER PTHR11773 1 484 1.2E-292 T 09-11-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 Gene3D G3DSA:3.40.50.2300 2 122 5.7E-38 T 09-11-2016 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 PANTHER PTHR26402 3 224 1.2E-140 T 09-11-2016 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 Pfam PF00072 Response regulator receiver domain 5 114 1.2E-28 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 SUPERFAMILY SSF52172 4 176 1.07E-39 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 SMART SM00448 3 113 1.1E-39 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 Gene3D G3DSA:1.10.10.10 128 224 1.4E-29 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 PANTHER PTHR26402:SF559 3 224 1.2E-140 T 09-11-2016 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 SMART SM00862 147 223 1.3E-22 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13325 67db5fba00c4237617a66c1047755ea4 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 5.0E-24 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 Pfam PF02733 Dak1 domain 18 328 1.3E-127 T 09-11-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 PANTHER PTHR28629:SF2 1 586 0.0 T 09-11-2016 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 Gene3D G3DSA:3.30.1180.20 183 331 1.3E-56 T 09-11-2016 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 378 581 8.9E-42 T 09-11-2016 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00563+2.7.-.- CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 SMART SM01120 400 583 2.2E-60 T 09-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 SUPERFAMILY SSF82549 1 331 1.99E-121 T 09-11-2016 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 Gene3D G3DSA:3.40.50.10440 11 181 9.0E-72 T 09-11-2016 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 SUPERFAMILY SSF101473 360 583 3.14E-45 T 09-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 Pfam PF02734 DAK2 domain 401 582 2.5E-49 T 09-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 9.2E-137 T 09-11-2016 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00563+2.7.-.-|UniPathway: UPA00616 CLOSPO_RS18285 90cbfdf2d5ba8c76953e7a8de4910612 586 PANTHER PTHR28629 1 586 0.0 T 09-11-2016 CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 SUPERFAMILY SSF54631 2 121 2.78E-32 T 09-11-2016 CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 Gene3D G3DSA:3.10.580.10 2 122 2.7E-32 T 09-11-2016 CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 PANTHER PTHR11911 4 122 3.5E-28 T 09-11-2016 CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 SMART SM00116 9 57 1.8E-6 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 SMART SM00116 74 122 9.9E-8 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 Pfam PF00571 CBS domain 2 57 1.1E-12 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS18895 b4bed2e4ee84aa808946501d47aac2a6 126 Pfam PF00571 CBS domain 70 121 1.1E-10 T 09-11-2016 IPR000644 CBS domain CLOSPO_RS17615 b93fcc5473192fb3b6744d69a5288aeb 111 PANTHER PTHR36116 1 111 5.1E-48 T 09-11-2016 CLOSPO_RS17615 b93fcc5473192fb3b6744d69a5288aeb 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 111 7.6E-44 T 09-11-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CLOSPO_RS17615 b93fcc5473192fb3b6744d69a5288aeb 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 110 22.812 T 09-11-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CLOSPO_RS17615 b93fcc5473192fb3b6744d69a5288aeb 111 SUPERFAMILY SSF103481 8 109 4.32E-8 T 09-11-2016 CLOSPO_RS17615 b93fcc5473192fb3b6744d69a5288aeb 111 PANTHER PTHR36116:SF1 1 111 5.1E-48 T 09-11-2016 CLOSPO_RS14940 6ed429ebeea65476e27c7d25d393b984 83 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 3 78 8.4E-31 T 09-11-2016 IPR023860 [FeFe]-hydrogenase system regulator TM1266 CLOSPO_RS14940 6ed429ebeea65476e27c7d25d393b984 83 SUPERFAMILY SSF55021 1 79 1.08E-24 T 09-11-2016 CLOSPO_RS14940 6ed429ebeea65476e27c7d25d393b984 83 Gene3D G3DSA:3.30.70.1150 1 82 7.7E-32 T 09-11-2016 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 SUPERFAMILY SSF52540 2 246 1.7E-52 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 ProSitePatterns PS00746 NifH/frxC family signature 1. 83 95 - T 09-11-2016 IPR030655 NifH/chlL conserved site CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 ProSitePatterns PS00692 NifH/frxC family signature 2. 122 135 - T 09-11-2016 IPR030655 NifH/chlL conserved site CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PANTHER PTHR13696:SF5 1 249 5.1E-134 T 09-11-2016 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PRINTS PR00091 Nitrogenase component II signature 29 44 5.8E-34 T 09-11-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PRINTS PR00091 Nitrogenase component II signature 121 136 5.8E-34 T 09-11-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PRINTS PR00091 Nitrogenase component II signature 7 20 5.8E-34 T 09-11-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PRINTS PR00091 Nitrogenase component II signature 81 95 5.8E-34 T 09-11-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PANTHER PTHR13696 1 249 5.1E-134 T 09-11-2016 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 PIRSF PIRSF000363 1 249 4.6E-101 T 09-11-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 Gene3D G3DSA:3.40.50.300 2 246 2.1E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16885 f93681673a93a10ffe9ef7c649cf248c 249 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 2 246 3.0E-96 T 09-11-2016 CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 175 7.6E-25 T 09-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 Pfam PF04542 Sigma-70 region 2 20 71 5.9E-5 T 09-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 Gene3D G3DSA:1.10.10.10 116 177 2.0E-7 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 SUPERFAMILY SSF88946 3 76 1.7E-13 T 09-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 Gene3D G3DSA:1.10.1740.10 3 91 1.1E-9 T 09-11-2016 CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 PANTHER PTHR30385 1 178 2.3E-26 T 09-11-2016 CLOSPO_RS17150 a6dcd1a1cb060c37c3733b9d149209a7 179 SUPERFAMILY SSF88659 108 176 3.92E-11 T 09-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS15220 caef0f32459f91edc7e23ccb5ac3063a 134 Gene3D G3DSA:2.40.50.140 2 77 4.1E-28 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS15220 caef0f32459f91edc7e23ccb5ac3063a 134 SMART SM00316 4 73 2.9E-27 T 09-11-2016 IPR022967 RNA-binding domain, S1 CLOSPO_RS15220 caef0f32459f91edc7e23ccb5ac3063a 134 SUPERFAMILY SSF50249 4 82 3.0E-25 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS15220 caef0f32459f91edc7e23ccb5ac3063a 134 Pfam PF00575 S1 RNA binding domain 3 73 6.1E-20 T 09-11-2016 IPR003029 S1 domain GO:0003676 CLOSPO_RS15220 caef0f32459f91edc7e23ccb5ac3063a 134 PANTHER PTHR10724 3 129 3.1E-39 T 09-11-2016 CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 PANTHER PTHR24220 4 249 3.5E-108 T 09-11-2016 CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 Gene3D G3DSA:3.40.50.300 3 230 2.3E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 SMART SM00382 27 212 3.0E-16 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 PANTHER PTHR24220:SF309 4 249 3.5E-108 T 09-11-2016 CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 SUPERFAMILY SSF52540 3 225 2.25E-61 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS18270 2d21837eb5c65053d4f5ba9de9e8a263 256 Pfam PF00005 ABC transporter 18 167 1.1E-31 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17245 1cc8410687c20c10691472de5fb57c46 324 Pfam PF00303 Thymidylate synthase 10 250 6.8E-20 T 09-11-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 CLOSPO_RS17245 1cc8410687c20c10691472de5fb57c46 324 Gene3D G3DSA:3.30.572.10 2 239 6.6E-51 T 09-11-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 CLOSPO_RS17245 1cc8410687c20c10691472de5fb57c46 324 SUPERFAMILY SSF55831 8 268 7.85E-52 T 09-11-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 CLOSPO_RS13260 ad4dc6f6188bb9cb8575a6b6f76e5419 256 PANTHER PTHR24220 5 244 3.1E-154 T 09-11-2016 CLOSPO_RS13260 ad4dc6f6188bb9cb8575a6b6f76e5419 256 SUPERFAMILY SSF52540 3 224 5.07E-68 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13260 ad4dc6f6188bb9cb8575a6b6f76e5419 256 Pfam PF00005 ABC transporter 25 173 2.7E-32 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13260 ad4dc6f6188bb9cb8575a6b6f76e5419 256 Gene3D G3DSA:3.40.50.300 2 223 1.2E-68 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13260 ad4dc6f6188bb9cb8575a6b6f76e5419 256 SMART SM00382 34 221 7.5E-14 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13260 ad4dc6f6188bb9cb8575a6b6f76e5419 256 PANTHER PTHR24220:SF583 5 244 3.1E-154 T 09-11-2016 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 4.3E-30 T 09-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 PANTHER PTHR34069 1 325 6.5E-140 T 09-11-2016 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 SUPERFAMILY SSF53901 4 324 1.76E-61 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 1.3E-30 T 09-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 PANTHER PTHR34069:SF2 1 325 6.5E-140 T 09-11-2016 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 Gene3D G3DSA:3.40.47.10 1 160 3.9E-61 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 Gene3D G3DSA:3.40.47.10 161 324 2.3E-50 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 324 68.071 T 09-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 CLOSPO_RS14825 6a01b910d710d009ab859eccf9f75f7e 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 323 7.4E-115 T 09-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 CLOSPO_RS14970 8058ee9919bf369d2b5c2fa2a5fea4c5 241 TIGRFAM TIGR01918 various_sel_PB: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family 27 220 4.8E-21 T 09-11-2016 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 CLOSPO_RS14970 8058ee9919bf369d2b5c2fa2a5fea4c5 241 Pfam PF07355 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 25 148 5.3E-13 T 09-11-2016 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 CLOSPO_RS14970 8058ee9919bf369d2b5c2fa2a5fea4c5 241 TIGRFAM TIGR04483 D_pro_red_PrdB: D-proline reductase (dithiol), PrdB protein 4 241 1.8E-141 T 09-11-2016 IPR022787 D-proline reductase (dithiol), PrdB protein GO:0050002|GO:0055114 KEGG: 00330+1.21.4.1 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 Gene3D G3DSA:1.20.1570.10 206 244 1.6E-46 T 09-11-2016 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 Gene3D G3DSA:1.20.1570.10 282 339 1.6E-46 T 09-11-2016 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 Hamap MF_01567 UPF0371 protein . 1 502 59.605 T 09-11-2016 IPR014999 Uncharacterised protein family UPF0371 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 Gene3D G3DSA:3.10.630.10 1 205 4.2E-121 T 09-11-2016 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 Gene3D G3DSA:3.10.630.10 251 281 4.2E-121 T 09-11-2016 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 PIRSF PIRSF033132 1 502 5.7E-268 T 09-11-2016 IPR014999 Uncharacterised protein family UPF0371 CLOSPO_RS13035 c90e53f72a48e29b76b59bea8d68ab8f 502 Pfam PF08903 Domain of unknown function (DUF1846) 3 499 7.2E-238 T 09-11-2016 IPR014999 Uncharacterised protein family UPF0371 CLOSPO_RS14905 528a374fcfd9027cce234df77d98a6a7 161 PIRSF PIRSF030140 1 161 1.3E-59 T 09-11-2016 IPR016947 Uncharacterised phage-associated protein UCP030140 CLOSPO_RS14905 528a374fcfd9027cce234df77d98a6a7 161 Gene3D G3DSA:1.10.287.1080 4 78 6.0E-4 T 09-11-2016 CLOSPO_RS14905 528a374fcfd9027cce234df77d98a6a7 161 SUPERFAMILY SSF101386 2 161 1.26E-47 T 09-11-2016 CLOSPO_RS14905 528a374fcfd9027cce234df77d98a6a7 161 Pfam PF08761 dUTPase 2 161 1.2E-49 T 09-11-2016 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 CLOSPO_RS16135 bea264b15b6e2f905b82740befe8df7e 231 SUPERFAMILY SSF52540 4 215 2.17E-45 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16135 bea264b15b6e2f905b82740befe8df7e 231 Pfam PF00005 ABC transporter 20 155 1.1E-21 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16135 bea264b15b6e2f905b82740befe8df7e 231 PANTHER PTHR24220:SF530 6 227 1.6E-110 T 09-11-2016 CLOSPO_RS16135 bea264b15b6e2f905b82740befe8df7e 231 Gene3D G3DSA:3.40.50.300 2 220 1.6E-49 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16135 bea264b15b6e2f905b82740befe8df7e 231 PANTHER PTHR24220 6 227 1.6E-110 T 09-11-2016 CLOSPO_RS16135 bea264b15b6e2f905b82740befe8df7e 231 SMART SM00382 29 204 2.0E-13 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS00490 401ca79440ef8af251a6a2ca0206c860 70 Pfam PF05228 CHASE4 domain 24 69 4.6E-9 T 09-11-2016 IPR007892 CHASE4 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 PRINTS PR01043 Glycyl-tRNA synthetase signature 22 39 2.0E-14 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 PRINTS PR01043 Glycyl-tRNA synthetase signature 146 155 2.0E-14 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 PRINTS PR01043 Glycyl-tRNA synthetase signature 39 49 2.0E-14 T 09-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 SUPERFAMILY SSF55681 1 154 4.98E-59 T 09-11-2016 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 10 109 8.5E-7 T 09-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 Gene3D G3DSA:3.30.930.10 1 154 1.2E-70 T 09-11-2016 CLOSPO_RS02910 eceb6ffa031719724da76c72713e970e 155 PANTHER PTHR10745 1 154 1.0E-72 T 09-11-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 PANTHER PTHR30204 1 251 3.3E-91 T 09-11-2016 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.3E-5 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.3E-5 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 8.3E-5 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 PANTHER PTHR30204:SF27 1 251 3.3E-91 T 09-11-2016 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 Gene3D G3DSA:1.10.1660.10 3 117 1.5E-30 T 09-11-2016 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 Pfam PF07739 TipAS antibiotic-recognition domain 135 249 8.8E-39 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 SUPERFAMILY SSF89082 164 251 2.22E-28 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 Pfam PF13411 MerR HTH family regulatory protein 3 71 1.8E-16 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 SUPERFAMILY SSF46955 3 115 4.76E-28 T 09-11-2016 IPR009061 Putative DNA-binding domain CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 SMART SM00422 3 72 4.4E-25 T 09-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS17960 5c86e0840e39791b82ebd8c5b36b6c50 255 Gene3D G3DSA:1.10.490.50 164 252 1.8E-29 T 09-11-2016 IPR012925 TipAS antibiotic-recognition domain CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 SUPERFAMILY SSF54826 6 142 2.57E-57 T 09-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 Pfam PF03952 Enolase, N-terminal domain 7 137 7.7E-61 T 09-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 Gene3D G3DSA:3.20.20.120 133 428 1.6E-137 T 09-11-2016 IPR029065 Enolase C-terminal domain-like CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 428 2.4E-212 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PANTHER PTHR11902 7 428 1.9E-270 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 426 2.1E-136 T 09-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 Gene3D G3DSA:3.30.390.10 7 129 3.5E-56 T 09-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 SUPERFAMILY SSF51604 142 428 2.04E-132 T 09-11-2016 IPR029065 Enolase C-terminal domain-like CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 SMART SM01192 142 428 2.3E-227 T 09-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PIRSF PIRSF001400 3 428 5.8E-192 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 Hamap MF_00318 Enolase [eno]. 5 414 45.168 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 SMART SM01193 7 137 3.7E-97 T 09-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PRINTS PR00148 Enolase signature 164 177 3.8E-47 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PRINTS PR00148 Enolase signature 40 54 3.8E-47 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PRINTS PR00148 Enolase signature 314 325 3.8E-47 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PRINTS PR00148 Enolase signature 337 351 3.8E-47 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PRINTS PR00148 Enolase signature 366 383 3.8E-47 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 PRINTS PR00148 Enolase signature 110 126 3.8E-47 T 09-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13555 44f8232bef0361eccdc897f4fb107995 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 09-11-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 SUPERFAMILY SSF55874 280 423 9.69E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 424 1.6E-14 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PANTHER PTHR24423:SF543 1 11 9.8E-20 T 09-11-2016 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PANTHER PTHR24423 243 432 9.8E-20 T 09-11-2016 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 Gene3D G3DSA:3.30.565.10 276 423 1.9E-20 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PANTHER PTHR24423:SF543 243 432 9.8E-20 T 09-11-2016 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PANTHER PTHR24423 1 11 9.8E-20 T 09-11-2016 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 1.6E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 1.6E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 1.6E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 1.6E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS16445 4c030fbf64e05e16cdac283faa3b93b2 432 SMART SM00387 307 426 4.3E-10 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 463 1.8E-192 T 09-11-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 Gene3D G3DSA:2.40.50.140 13 103 1.2E-18 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 SUPERFAMILY SSF55681 104 461 4.11E-98 T 09-11-2016 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 Gene3D G3DSA:3.30.930.10 106 459 2.2E-115 T 09-11-2016 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 457 2.0E-87 T 09-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 Pfam PF01336 OB-fold nucleic acid binding domain 21 98 4.4E-10 T 09-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PANTHER PTHR22594 1 177 1.7E-248 T 09-11-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PANTHER PTHR22594 196 462 1.7E-248 T 09-11-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 SUPERFAMILY SSF50249 13 102 4.95E-18 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 378 394 1.1E-12 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 418 432 1.1E-12 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 217 1.1E-12 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 221 234 1.1E-12 T 09-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 463 46.484 T 09-11-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PANTHER PTHR22594:SF6 1 177 1.7E-248 T 09-11-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 CLOSPO_RS16335 c17dd1f6bcebadf7e82579ac4b96a96b 463 PANTHER PTHR22594:SF6 196 462 1.7E-248 T 09-11-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 CLOSPO_RS05135 a1196ad3177aa0645df7c74e71e91cd0 69 Pfam PF00581 Rhodanese-like domain 2 56 1.5E-8 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS05135 a1196ad3177aa0645df7c74e71e91cd0 69 SUPERFAMILY SSF52821 2 62 6.94E-16 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS05135 a1196ad3177aa0645df7c74e71e91cd0 69 Gene3D G3DSA:3.40.250.10 2 62 1.9E-17 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS05135 a1196ad3177aa0645df7c74e71e91cd0 69 PANTHER PTHR11364:SF0 2 69 5.1E-20 T 09-11-2016 CLOSPO_RS05135 a1196ad3177aa0645df7c74e71e91cd0 69 PANTHER PTHR11364 2 69 5.1E-20 T 09-11-2016 CLOSPO_RS13070 82dde666d0bbc7b843943f053ac2d3a1 620 PANTHER PTHR30489 1 619 0.0 T 09-11-2016 CLOSPO_RS13070 82dde666d0bbc7b843943f053ac2d3a1 620 PIRSF PIRSF018968 1 616 5.5E-124 T 09-11-2016 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CLOSPO_RS13070 82dde666d0bbc7b843943f053ac2d3a1 620 Pfam PF02687 FtsX-like permease family 61 174 6.5E-11 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS13070 82dde666d0bbc7b843943f053ac2d3a1 620 PANTHER PTHR30489:SF13 1 619 0.0 T 09-11-2016 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 Gene3D G3DSA:1.10.287.130 237 299 5.3E-19 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 Pfam PF00672 HAMP domain 174 242 1.8E-15 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 1.8E-6 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.8E-6 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 1.8E-6 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 1.8E-6 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 SMART SM00304 194 246 2.5E-13 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PANTHER PTHR24423 188 469 1.3E-84 T 09-11-2016 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 313 1.1E-16 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 Gene3D G3DSA:3.30.565.10 300 468 2.0E-41 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 SMART SM00387 359 469 6.1E-27 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 SUPERFAMILY SSF158472 194 243 5.89E-11 T 09-11-2016 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 SUPERFAMILY SSF47384 230 314 2.75E-19 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 SMART SM00388 247 313 1.6E-19 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PANTHER PTHR24423 45 123 1.3E-84 T 09-11-2016 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PANTHER PTHR24423:SF394 45 123 1.3E-84 T 09-11-2016 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 PANTHER PTHR24423:SF394 188 469 1.3E-84 T 09-11-2016 CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 SUPERFAMILY SSF55874 302 467 5.11E-39 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 467 4.6E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15155 d17002622d17fcc6b6e50936d0b8bcc8 469 Gene3D G3DSA:3.30.450.20 32 164 9.9E-9 T 09-11-2016 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 SUPERFAMILY SSF46689 13 78 2.87E-11 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 Pfam PF01380 SIS domain 120 240 1.3E-13 T 09-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 PANTHER PTHR30514:SF1 14 249 8.5E-55 T 09-11-2016 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 PANTHER PTHR30514 14 249 8.5E-55 T 09-11-2016 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 SUPERFAMILY SSF53697 93 250 2.63E-24 T 09-11-2016 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 12 73 3.1E-9 T 09-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 Gene3D G3DSA:3.40.50.10490 65 249 1.1E-26 T 09-11-2016 CLOSPO_RS13230 c93ac7c46f4cb39f11eb01f2c260b09c 253 Gene3D G3DSA:1.10.10.10 13 64 4.2E-12 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17915 7ae6b26c6e53ef19b099ccabd8958ac5 65 SMART SM00530 4 59 1.1E-17 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17915 7ae6b26c6e53ef19b099ccabd8958ac5 65 Pfam PF01381 Helix-turn-helix 5 58 5.2E-19 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17915 7ae6b26c6e53ef19b099ccabd8958ac5 65 PANTHER PTHR10245 1 65 2.6E-22 T 09-11-2016 CLOSPO_RS17915 7ae6b26c6e53ef19b099ccabd8958ac5 65 Gene3D G3DSA:1.10.260.40 1 64 1.2E-27 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17915 7ae6b26c6e53ef19b099ccabd8958ac5 65 PANTHER PTHR10245:SF26 1 65 2.6E-22 T 09-11-2016 CLOSPO_RS17915 7ae6b26c6e53ef19b099ccabd8958ac5 65 SUPERFAMILY SSF47413 2 64 2.04E-20 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS14405 b844857a67a922f9e0143f15d35206a9 207 PANTHER PTHR40056 1 203 2.3E-49 T 09-11-2016 CLOSPO_RS14405 b844857a67a922f9e0143f15d35206a9 207 Gene3D G3DSA:1.10.238.10 98 190 4.8E-4 T 09-11-2016 IPR011992 EF-hand domain pair CLOSPO_RS14405 b844857a67a922f9e0143f15d35206a9 207 PANTHER PTHR40056:SF1 1 203 2.3E-49 T 09-11-2016 CLOSPO_RS14405 b844857a67a922f9e0143f15d35206a9 207 Pfam PF08876 Domain of unknown function (DUF1836) 26 129 7.9E-25 T 09-11-2016 IPR014975 Protein of unknown function DUF1836 CLOSPO_RS12810 056e0367766e947a0c6201338a930b0d 199 PIRSF PIRSF006102 1 199 1.1E-75 T 09-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CLOSPO_RS12810 056e0367766e947a0c6201338a930b0d 199 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 194 3.9E-83 T 09-11-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 CLOSPO_RS12810 056e0367766e947a0c6201338a930b0d 199 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 187 6.6E-69 T 09-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 CLOSPO_RS12810 056e0367766e947a0c6201338a930b0d 199 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 197 26.529 T 09-11-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 CLOSPO_RS12810 056e0367766e947a0c6201338a930b0d 199 PANTHER PTHR30586 1 199 1.7E-114 T 09-11-2016 CLOSPO_RS12680 bf76a5b4f07b594b60d4060a45f91478 183 Pfam PF02659 Putative manganese efflux pump 31 181 4.9E-31 T 09-11-2016 IPR003810 Putative manganese efflux pump CLOSPO_RS12680 bf76a5b4f07b594b60d4060a45f91478 183 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 183 19.483 T 09-11-2016 IPR022929 Putative manganese efflux pump MntP CLOSPO_RS12680 bf76a5b4f07b594b60d4060a45f91478 183 PANTHER PTHR35529 2 182 4.2E-57 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PANTHER PTHR22912:SF141 1 380 1.7E-154 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 Gene3D G3DSA:3.50.50.60 1 115 3.4E-24 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.4E-25 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 4.4E-25 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 4.4E-25 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 4.4E-25 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 4.4E-25 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 Gene3D G3DSA:3.50.50.60 116 316 3.1E-32 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 296 4.1E-36 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PANTHER PTHR22912 1 380 1.7E-154 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 SUPERFAMILY SSF51905 1 324 5.18E-43 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.4E-18 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 8.4E-18 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 8.4E-18 T 09-11-2016 CLOSPO_RS18865 4655d9824c9a0d1189dd5ec23d64ed0a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 248 262 8.4E-18 T 09-11-2016 CLOSPO_RS17530 f3d15aec33d6294c8db6b70567df6266 82 Pfam PF07875 Coat F domain 2 63 3.5E-22 T 09-11-2016 IPR012851 Spore coat protein CotF-like CLOSPO_RS17495 21fe9114716b7e22c7c4bbcf72d3fa15 507 Pfam PF07670 Nucleoside recognition 353 477 2.3E-15 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS17495 21fe9114716b7e22c7c4bbcf72d3fa15 507 Pfam PF07670 Nucleoside recognition 181 270 8.7E-6 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS17495 21fe9114716b7e22c7c4bbcf72d3fa15 507 PANTHER PTHR11649:SF37 91 507 1.7E-101 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS17495 21fe9114716b7e22c7c4bbcf72d3fa15 507 PANTHER PTHR11649 91 507 1.7E-101 T 09-11-2016 CLOSPO_RS17495 21fe9114716b7e22c7c4bbcf72d3fa15 507 Pfam PF07664 Ferrous iron transport protein B C terminus 295 343 3.2E-14 T 09-11-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 Pfam PF07687 Peptidase dimerisation domain 185 274 5.1E-7 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 374 5.1E-111 T 09-11-2016 IPR017439 Amidohydrolase GO:0016787 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 SUPERFAMILY SSF55031 183 289 2.22E-26 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 Gene3D G3DSA:3.30.70.360 181 296 2.3E-36 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 PIRSF PIRSF005962 1 388 1.9E-128 T 09-11-2016 IPR017439 Amidohydrolase GO:0016787 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 PANTHER PTHR11014:SF63 10 387 2.4E-162 T 09-11-2016 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 SUPERFAMILY SSF53187 2 196 4.79E-80 T 09-11-2016 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 SUPERFAMILY SSF53187 297 387 4.79E-80 T 09-11-2016 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 PANTHER PTHR11014 10 387 2.4E-162 T 09-11-2016 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 Gene3D G3DSA:3.40.630.10 4 177 2.7E-93 T 09-11-2016 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 Gene3D G3DSA:3.40.630.10 297 387 2.7E-93 T 09-11-2016 CLOSPO_RS18950 d5281d5f2530abe1a40a576918bd9789 388 Pfam PF01546 Peptidase family M20/M25/M40 72 382 5.2E-29 T 09-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 Gene3D G3DSA:3.40.640.10 17 249 7.1E-78 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 SUPERFAMILY SSF53383 17 372 8.58E-113 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 Gene3D G3DSA:3.90.1150.10 252 372 5.9E-41 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 PANTHER PTHR30244 1 373 3.4E-195 T 09-11-2016 CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 367 8.7E-115 T 09-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 PIRSF PIRSF000390 2 373 6.7E-103 T 09-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOSPO_RS17570 ff4d845b13f9356fd59ed0b6f33652a5 373 PANTHER PTHR30244:SF15 1 373 3.4E-195 T 09-11-2016 CLOSPO_RS17260 c900f26a66a20cacb97549a2c4401d41 277 PANTHER PTHR20858 1 262 3.8E-129 T 09-11-2016 CLOSPO_RS17260 c900f26a66a20cacb97549a2c4401d41 277 PANTHER PTHR20858:SF17 1 262 3.8E-129 T 09-11-2016 CLOSPO_RS17260 c900f26a66a20cacb97549a2c4401d41 277 SUPERFAMILY SSF53613 1 265 6.55E-83 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS17260 c900f26a66a20cacb97549a2c4401d41 277 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 256 3.0E-106 T 09-11-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOSPO_RS17260 c900f26a66a20cacb97549a2c4401d41 277 Pfam PF08543 Phosphomethylpyrimidine kinase 11 254 5.7E-96 T 09-11-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 CLOSPO_RS17260 c900f26a66a20cacb97549a2c4401d41 277 Gene3D G3DSA:3.40.1190.20 1 256 9.0E-102 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 SUPERFAMILY SSF48264 13 417 1.44E-67 T 09-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 PANTHER PTHR24302:SF10 83 415 1.8E-104 T 09-11-2016 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 PRINTS PR00463 E-class P450 group I signature 365 388 1.9E-8 T 09-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 PRINTS PR00463 E-class P450 group I signature 319 343 1.9E-8 T 09-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 PRINTS PR00463 E-class P450 group I signature 253 279 1.9E-8 T 09-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 Gene3D G3DSA:1.10.630.10 13 417 7.5E-51 T 09-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 PANTHER PTHR24302 83 415 1.8E-104 T 09-11-2016 CLOSPO_RS18630 3c045937296d4fc1fd3e1e47d12cfaf2 419 Pfam PF00067 Cytochrome P450 277 395 4.2E-17 T 09-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 CLOSPO_RS17715 9f9308dbdf4bce9a8a643dc3c46239fb 156 PANTHER PTHR34390 1 156 6.7E-44 T 09-11-2016 CLOSPO_RS17715 9f9308dbdf4bce9a8a643dc3c46239fb 156 Pfam PF12821 Threonine/Serine exporter, ThrE 7 135 4.7E-33 T 09-11-2016 IPR024528 Threonine/Serine exporter, ThrE CLOSPO_RS12660 681a268c50124f0988d2b18005304bf3 344 PANTHER PTHR22936 3 343 2.2E-49 T 09-11-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 CLOSPO_RS12660 681a268c50124f0988d2b18005304bf3 344 Gene3D G3DSA:1.20.1540.10 154 334 2.4E-43 T 09-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CLOSPO_RS12660 681a268c50124f0988d2b18005304bf3 344 Pfam PF01694 Rhomboid family 198 337 3.9E-37 T 09-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CLOSPO_RS12660 681a268c50124f0988d2b18005304bf3 344 SUPERFAMILY SSF144091 153 338 2.62E-46 T 09-11-2016 CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 PANTHER PTHR24220 3 249 1.0E-105 T 09-11-2016 CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 Gene3D G3DSA:3.40.50.300 1 248 1.0E-75 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 SMART SM00382 33 234 5.5E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 Pfam PF00005 ABC transporter 24 176 4.6E-29 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 PANTHER PTHR24220:SF529 3 249 1.0E-105 T 09-11-2016 CLOSPO_RS16645 0746e22cbe4529f445204e2af13bc44b 256 SUPERFAMILY SSF52540 1 247 9.58E-69 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 Gene3D G3DSA:1.20.1560.10 24 329 1.9E-19 T 09-11-2016 CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 PANTHER PTHR24221 95 579 1.7E-78 T 09-11-2016 CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 SUPERFAMILY SSF52540 339 584 1.22E-56 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 PANTHER PTHR24221:SF157 95 579 1.7E-78 T 09-11-2016 CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 Gene3D G3DSA:3.40.50.300 349 579 3.3E-54 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 SUPERFAMILY SSF90123 15 332 4.19E-28 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 Pfam PF00005 ABC transporter 366 514 2.5E-29 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16575 be2c10f3eb26ef546a89b35b2af11a1b 594 SMART SM00382 375 562 5.8E-11 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 7.8E-7 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 7.8E-7 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 SUPERFAMILY SSF46689 282 330 4.35E-11 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 PANTHER PTHR11019 13 155 3.5E-87 T 09-11-2016 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 PANTHER PTHR11019 171 333 3.5E-87 T 09-11-2016 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 SMART SM00342 245 328 6.0E-24 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 282 324 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 PANTHER PTHR11019:SF61 171 333 3.5E-87 T 09-11-2016 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 Gene3D G3DSA:1.10.10.60 228 281 2.0E-8 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 PANTHER PTHR11019:SF61 13 155 3.5E-87 T 09-11-2016 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 Pfam PF12833 Helix-turn-helix domain 251 329 1.2E-18 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18710 436596eb2b0d8d55623e0b6b3b724941 333 Gene3D G3DSA:1.10.10.60 282 328 2.2E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 PANTHER PTHR33280:SF2 1 69 1.0E-39 T 09-11-2016 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 1.5E-31 T 09-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 09-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 29.204 T 09-11-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 PANTHER PTHR33280 1 69 1.0E-39 T 09-11-2016 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 SUPERFAMILY SSF143800 1 66 7.06E-27 T 09-11-2016 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 PRINTS PR01249 Ribosomal protein L31 signature 31 46 1.0E-19 T 09-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-19 T 09-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 PRINTS PR01249 Ribosomal protein L31 signature 46 64 1.0E-19 T 09-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14050 89181bb434e980e50689cc8510764bf5 72 Pfam PF01197 Ribosomal protein L31 1 65 1.0E-32 T 09-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 Gene3D G3DSA:1.10.287.80 6 38 7.8E-45 T 09-11-2016 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 Gene3D G3DSA:1.10.287.80 215 280 7.8E-45 T 09-11-2016 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 Gene3D G3DSA:3.40.1380.10 67 189 3.0E-32 T 09-11-2016 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 Pfam PF00231 ATP synthase 8 280 1.5E-78 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 PANTHER PTHR11693 4 282 2.4E-85 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 Hamap MF_00815 ATP synthase gamma chain [atpG]. 3 281 29.209 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 267 280 - T 09-11-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 5 280 2.9E-77 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 SUPERFAMILY SSF52943 5 280 7.06E-75 T 09-11-2016 IPR023633 ATPase, F1 complex, gamma subunit domain CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.3E-28 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 PRINTS PR00126 ATP synthase gamma subunit signature 228 247 1.3E-28 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 PRINTS PR00126 ATP synthase gamma subunit signature 164 181 1.3E-28 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13950 f3e57ed7e97ed15a1156ceb8c755e577 282 PRINTS PR00126 ATP synthase gamma subunit signature 259 280 1.3E-28 T 09-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 CLOSPO_RS13040 2f5f607bc9d1c29bf8479ad48608e39d 297 PANTHER PTHR11228 2 231 8.8E-54 T 09-11-2016 CLOSPO_RS13040 2f5f607bc9d1c29bf8479ad48608e39d 297 SUPERFAMILY SSF102114 22 210 1.83E-10 T 09-11-2016 CLOSPO_RS13040 2f5f607bc9d1c29bf8479ad48608e39d 297 Pfam PF04055 Radical SAM superfamily 26 195 2.4E-11 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS13040 2f5f607bc9d1c29bf8479ad48608e39d 297 Gene3D G3DSA:3.20.20.70 19 207 8.7E-7 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS13040 2f5f607bc9d1c29bf8479ad48608e39d 297 PANTHER PTHR11228:SF26 2 231 8.8E-54 T 09-11-2016 CLOSPO_RS13040 2f5f607bc9d1c29bf8479ad48608e39d 297 SMART SM00729 22 245 3.9E-4 T 09-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CLOSPO_RS12600 b2b21449105518e2ad6f82cf7d8785a5 242 Gene3D G3DSA:3.40.50.880 16 202 2.5E-15 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS12600 b2b21449105518e2ad6f82cf7d8785a5 242 PANTHER PTHR21343 1 239 3.4E-117 T 09-11-2016 CLOSPO_RS12600 b2b21449105518e2ad6f82cf7d8785a5 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 4 198 2.9E-46 T 09-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 CLOSPO_RS12600 b2b21449105518e2ad6f82cf7d8785a5 242 SUPERFAMILY SSF52317 14 192 1.02E-28 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS12600 b2b21449105518e2ad6f82cf7d8785a5 242 PANTHER PTHR21343:SF9 1 239 3.4E-117 T 09-11-2016 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 Pfam PF04607 Region found in RelA / SpoT proteins 45 164 3.8E-35 T 09-11-2016 IPR007685 RelA/SpoT GO:0015969 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 PANTHER PTHR21262 5 261 2.2E-124 T 09-11-2016 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 Gene3D G3DSA:1.10.287.860 149 203 1.8E-22 T 09-11-2016 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 PANTHER PTHR21262:SF11 5 261 2.2E-124 T 09-11-2016 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 SUPERFAMILY SSF81301 5 199 1.03E-56 T 09-11-2016 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 SMART SM00954 45 166 5.6E-41 T 09-11-2016 IPR007685 RelA/SpoT GO:0015969 CLOSPO_RS13790 8112c5b9fed9599f0609e1f597fe0b97 262 Gene3D G3DSA:3.30.460.10 5 146 6.7E-39 T 09-11-2016 CLOSPO_RS16875 262963ce583987c2fb0fa2e8176df265 346 Gene3D G3DSA:1.10.3470.10 18 345 5.5E-102 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS16875 262963ce583987c2fb0fa2e8176df265 346 SUPERFAMILY SSF81345 11 341 2.88E-84 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS16875 262963ce583987c2fb0fa2e8176df265 346 Pfam PF01032 FecCD transport family 31 341 1.5E-97 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS16875 262963ce583987c2fb0fa2e8176df265 346 PANTHER PTHR30472 1 345 2.9E-147 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS16875 262963ce583987c2fb0fa2e8176df265 346 PANTHER PTHR30472:SF16 1 345 2.9E-147 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 SUPERFAMILY SSF53187 1 222 1.34E-80 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 SUPERFAMILY SSF53187 332 405 1.34E-80 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 Pfam PF07687 Peptidase dimerisation domain 211 308 3.8E-6 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 PANTHER PTHR32494 1 407 2.9E-161 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 SUPERFAMILY SSF55031 212 320 3.14E-21 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 Gene3D G3DSA:3.30.70.360 225 317 2.3E-27 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 Pfam PF01546 Peptidase family M20/M25/M40 79 402 2.5E-27 T 09-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 Gene3D G3DSA:3.40.630.10 347 406 1.5E-99 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 Gene3D G3DSA:3.40.630.10 2 224 1.5E-99 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 PANTHER PTHR32494:SF5 1 407 2.9E-161 T 09-11-2016 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 403 8.9E-117 T 09-11-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 CLOSPO_RS16505 d31f1d06c61a97e2616afd403ed82c9c 407 PIRSF PIRSF001235 3 407 1.4E-125 T 09-11-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 PANTHER PTHR24220 7 224 1.2E-103 T 09-11-2016 CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 Gene3D G3DSA:3.40.50.300 3 227 1.3E-60 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 PANTHER PTHR24220:SF523 7 224 1.2E-103 T 09-11-2016 CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 Pfam PF00005 ABC transporter 22 162 9.6E-31 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 SUPERFAMILY SSF52540 4 224 1.46E-55 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17290 65fe7ea25b6943ae4e24f5a761cad0f1 306 SMART SM00382 30 212 1.1E-8 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 3 318 1.4E-152 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 SMART SM01004 1 319 1.0E-233 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PANTHER PTHR11458 2 323 2.9E-195 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 238 250 - T 09-11-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PIRSF PIRSF001415 1 322 6.7E-151 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 SUPERFAMILY SSF51569 2 321 2.78E-144 T 09-11-2016 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 Gene3D G3DSA:3.20.20.70 2 322 1.4E-153 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 293 312 5.3E-60 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 263 278 5.3E-60 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 118 132 5.3E-60 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 186 205 5.3E-60 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 238 254 5.3E-60 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS18020 af92cd1abcd67583eca735994317866a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 148 167 5.3E-60 T 09-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 TIGRFAM TIGR00165 S18: ribosomal protein bS18 13 79 1.4E-33 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 09-11-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 PANTHER PTHR13479 9 79 7.9E-29 T 09-11-2016 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 80 3.0E-23 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 3.6E-19 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 3.6E-19 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 3.6E-19 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 3.6E-19 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 Gene3D G3DSA:4.10.640.10 15 79 3.2E-33 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 80 22.688 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 SUPERFAMILY SSF46911 7 79 1.05E-29 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14665 f25b093948b9ef3e63c4005edbc562a8 80 Pfam PF01084 Ribosomal protein S18 25 75 1.9E-28 T 09-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS09080 17e95d1be9d453ef77e5c5e9e1522992 76 PANTHER PTHR22573:SF54 1 76 6.7E-29 T 09-11-2016 CLOSPO_RS09080 17e95d1be9d453ef77e5c5e9e1522992 76 Gene3D G3DSA:3.40.120.10 3 55 1.8E-12 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS09080 17e95d1be9d453ef77e5c5e9e1522992 76 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 3 55 3.7E-13 T 09-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS09080 17e95d1be9d453ef77e5c5e9e1522992 76 PANTHER PTHR22573 1 76 6.7E-29 T 09-11-2016 CLOSPO_RS09080 17e95d1be9d453ef77e5c5e9e1522992 76 SUPERFAMILY SSF53738 4 55 3.77E-11 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS16535 8f4820c73b4287be95d8fdd49ee781a2 137 PANTHER PTHR35813 8 137 6.8E-51 T 09-11-2016 CLOSPO_RS16535 8f4820c73b4287be95d8fdd49ee781a2 137 Pfam PF04304 Protein of unknown function (DUF454) 21 136 3.3E-36 T 09-11-2016 IPR007401 Protein of unknown function DUF454 CLOSPO_RS16535 8f4820c73b4287be95d8fdd49ee781a2 137 PANTHER PTHR35813:SF1 8 137 6.8E-51 T 09-11-2016 CLOSPO_RS16535 8f4820c73b4287be95d8fdd49ee781a2 137 PIRSF PIRSF016789 20 137 2.3E-30 T 09-11-2016 IPR007401 Protein of unknown function DUF454 CLOSPO_RS13480 958ba0d7afc4fd35a36275692f658e56 809 Gene3D G3DSA:3.30.565.10 369 583 2.7E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13480 958ba0d7afc4fd35a36275692f658e56 809 SUPERFAMILY SSF55874 370 580 3.01E-30 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13480 958ba0d7afc4fd35a36275692f658e56 809 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 506 3.1E-10 T 09-11-2016 CLOSPO_RS13480 958ba0d7afc4fd35a36275692f658e56 809 PANTHER PTHR11528 387 546 2.6E-18 T 09-11-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CLOSPO_RS13480 958ba0d7afc4fd35a36275692f658e56 809 PANTHER PTHR11528:SF26 387 546 2.6E-18 T 09-11-2016 CLOSPO_RS17640 b7f0cc9bafb4cb620dd615052f75609b 364 SUPERFAMILY SSF53649 38 360 5.47E-31 T 09-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CLOSPO_RS17640 b7f0cc9bafb4cb620dd615052f75609b 364 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 43 253 5.6E-12 T 09-11-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CLOSPO_RS17640 b7f0cc9bafb4cb620dd615052f75609b 364 Gene3D G3DSA:3.40.720.10 40 247 5.1E-19 T 09-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CLOSPO_RS15650 9832676ec6de7000551613fdbd6d92c6 189 PANTHER PTHR34478:SF2 2 189 1.2E-95 T 09-11-2016 CLOSPO_RS15650 9832676ec6de7000551613fdbd6d92c6 189 Gene3D G3DSA:1.20.1440.20 17 187 5.3E-68 T 09-11-2016 IPR023353 LemA-like domain CLOSPO_RS15650 9832676ec6de7000551613fdbd6d92c6 189 Pfam PF04011 LemA family 10 187 5.7E-73 T 09-11-2016 IPR007156 LemA CLOSPO_RS15650 9832676ec6de7000551613fdbd6d92c6 189 SUPERFAMILY SSF140478 29 176 2.22E-55 T 09-11-2016 IPR023353 LemA-like domain CLOSPO_RS15650 9832676ec6de7000551613fdbd6d92c6 189 PANTHER PTHR34478 2 189 1.2E-95 T 09-11-2016 CLOSPO_RS14185 438142510c92f225289fb054c1afbacd 371 PANTHER PTHR12526 1 370 4.1E-73 T 09-11-2016 CLOSPO_RS14185 438142510c92f225289fb054c1afbacd 371 Pfam PF00534 Glycosyl transferases group 1 188 348 7.3E-35 T 09-11-2016 IPR001296 Glycosyl transferase, family 1 CLOSPO_RS14185 438142510c92f225289fb054c1afbacd 371 PANTHER PTHR12526:SF399 1 370 4.1E-73 T 09-11-2016 CLOSPO_RS14185 438142510c92f225289fb054c1afbacd 371 Pfam PF13439 Glycosyltransferase Family 4 77 170 4.5E-8 T 09-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain CLOSPO_RS14185 438142510c92f225289fb054c1afbacd 371 SUPERFAMILY SSF53756 11 370 2.11E-76 T 09-11-2016 CLOSPO_RS14185 438142510c92f225289fb054c1afbacd 371 Gene3D G3DSA:3.40.50.2000 157 348 8.8E-28 T 09-11-2016 CLOSPO_RS15640 b728da76d5f31a625f8604cad504a088 146 PANTHER PTHR34390 1 145 4.7E-44 T 09-11-2016 CLOSPO_RS15640 b728da76d5f31a625f8604cad504a088 146 Pfam PF12821 Threonine/Serine exporter, ThrE 4 131 4.1E-39 T 09-11-2016 IPR024528 Threonine/Serine exporter, ThrE CLOSPO_RS18500 0160cfb22b4ba6e2f38e0bc285bbcfb0 156 SUPERFAMILY SSF46785 37 151 2.68E-20 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18500 0160cfb22b4ba6e2f38e0bc285bbcfb0 156 Gene3D G3DSA:1.10.10.10 36 151 3.2E-23 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18500 0160cfb22b4ba6e2f38e0bc285bbcfb0 156 Pfam PF01047 MarR family 39 93 7.4E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS18500 0160cfb22b4ba6e2f38e0bc285bbcfb0 156 PANTHER PTHR35790:SF1 2 156 1.9E-37 T 09-11-2016 CLOSPO_RS18500 0160cfb22b4ba6e2f38e0bc285bbcfb0 156 SMART SM00347 29 132 3.5E-11 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS18500 0160cfb22b4ba6e2f38e0bc285bbcfb0 156 PANTHER PTHR35790 2 156 1.9E-37 T 09-11-2016 CLOSPO_RS15395 82de96233c4ee4822c60a548f0f59dcf 480 Pfam PF13786 Domain of unknown function (DUF4179) 56 145 3.5E-23 T 09-11-2016 IPR025436 Domain of unknown function DUF4179 CLOSPO_RS15395 82de96233c4ee4822c60a548f0f59dcf 480 Gene3D G3DSA:2.60.40.1630 86 226 1.2E-36 T 09-11-2016 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PANTHER PTHR32092 1 441 0.0 T 09-11-2016 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 Gene3D G3DSA:3.90.110.10 167 440 6.8E-103 T 09-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 SUPERFAMILY SSF51735 3 164 5.47E-53 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 Gene3D G3DSA:3.40.50.720 1 165 9.6E-65 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 1.5E-56 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 416 7.8E-54 T 09-11-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 09-11-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 Pfam PF02056 Family 4 glycosyl hydrolase 6 184 5.6E-66 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 SUPERFAMILY SSF56327 168 441 4.48E-97 T 09-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CLOSPO_RS13240 cb5fcbc89111d9971bded0cd17fd693c 441 PANTHER PTHR32092:SF7 1 441 0.0 T 09-11-2016 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 155 9.2E-59 T 09-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 Gene3D G3DSA:3.30.360.10 164 318 8.3E-80 T 09-11-2016 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 SMART SM00846 3 155 2.9E-92 T 09-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PANTHER PTHR10836 1 338 1.0E-230 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 Gene3D G3DSA:3.40.50.720 2 163 1.9E-75 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 SUPERFAMILY SSF51735 3 171 2.81E-63 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 6.2E-42 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 6.2E-42 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 6.2E-42 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 6.2E-42 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 6.2E-42 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 09-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 2.8E-71 T 09-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PANTHER PTHR10836:SF50 1 338 1.0E-230 T 09-11-2016 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 PIRSF PIRSF000149 1 338 4.3E-140 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 2.8E-141 T 09-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS18985 902fdbfb84002de301a7bae55e8f615b 338 SUPERFAMILY SSF55347 155 317 2.11E-74 T 09-11-2016 CLOSPO_RS12775 c05495f6579015fa342e3d53b05a278b 1239 PANTHER PTHR30032:SF6 1 358 1.6E-96 T 09-11-2016 CLOSPO_RS12775 c05495f6579015fa342e3d53b05a278b 1239 PANTHER PTHR30032 1 358 1.6E-96 T 09-11-2016 CLOSPO_RS12775 c05495f6579015fa342e3d53b05a278b 1239 Pfam PF04122 Putative cell wall binding repeat 2 136 226 4.4E-13 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12775 c05495f6579015fa342e3d53b05a278b 1239 Pfam PF04122 Putative cell wall binding repeat 2 37 123 4.9E-19 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12775 c05495f6579015fa342e3d53b05a278b 1239 Pfam PF04122 Putative cell wall binding repeat 2 238 330 3.2E-15 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS15635 d9ef11db8018b7bbc50e8dbdf700df23 252 PANTHER PTHR31082 1 246 5.3E-84 T 09-11-2016 CLOSPO_RS15635 d9ef11db8018b7bbc50e8dbdf700df23 252 Pfam PF06738 Putative threonine/serine exporter 9 246 6.1E-69 T 09-11-2016 IPR010619 Putative threonine/serine exporter CLOSPO_RS15635 d9ef11db8018b7bbc50e8dbdf700df23 252 PANTHER PTHR31082:SF6 1 246 5.3E-84 T 09-11-2016 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 3.6E-100 T 09-11-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 Pfam PF00698 Acyl transferase domain 6 287 5.6E-35 T 09-11-2016 IPR014043 Acyl transferase CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 PIRSF PIRSF000446 1 310 1.2E-102 T 09-11-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 Gene3D G3DSA:3.40.366.10 196 306 4.0E-73 T 09-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 Gene3D G3DSA:3.40.366.10 2 121 4.0E-73 T 09-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 SUPERFAMILY SSF52151 189 309 2.2E-75 T 09-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 SUPERFAMILY SSF52151 4 121 2.2E-75 T 09-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 1.4E-36 T 09-11-2016 IPR020801 Polyketide synthase, acyl transferase domain CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 PANTHER PTHR10982 1 307 5.0E-150 T 09-11-2016 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 Gene3D G3DSA:3.30.70.250 124 195 4.8E-28 T 09-11-2016 CLOSPO_RS14840 540e1cb28ee6f812d8ce48c4e5a1b19e 314 SUPERFAMILY SSF55048 129 196 1.7E-16 T 09-11-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PANTHER PTHR11946 2 599 0.0 T 09-11-2016 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PANTHER PTHR11946:SF1 2 599 0.0 T 09-11-2016 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 SUPERFAMILY SSF50249 542 642 1.69E-32 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Gene3D G3DSA:2.40.50.140 534 644 8.9E-42 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Gene3D G3DSA:1.10.730.10 339 507 4.1E-53 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Pfam PF08264 Anticodon-binding domain of tRNA 391 533 9.4E-7 T 09-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 511 644 2.2E-45 T 09-11-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 SUPERFAMILY SSF52374 3 348 1.48E-117 T 09-11-2016 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Pfam PF01588 Putative tRNA binding domain 549 641 4.1E-29 T 09-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 09-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 SUPERFAMILY SSF47323 351 557 3.36E-45 T 09-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Pfam PF09334 tRNA synthetases class I (M) 148 361 1.0E-68 T 09-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 4 134 6.5E-11 T 09-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 506 50.9 T 09-11-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 3.7E-34 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 3.7E-34 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 3.7E-34 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.7E-34 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 3.7E-34 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.7E-34 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Gene3D G3DSA:3.40.50.620 3 114 4.1E-76 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Gene3D G3DSA:3.40.50.620 226 334 4.1E-76 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 Gene3D G3DSA:2.170.220.10 117 225 1.7E-47 T 09-11-2016 CLOSPO_RS14350 7cf48ff6af65d08efb08063ff7e8e5ff 645 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 508 3.4E-177 T 09-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 71 4.0E-22 T 09-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 Pfam PF00550 Phosphopantetheine attachment site 4 68 9.9E-15 T 09-11-2016 IPR009081 Phosphopantetheine binding ACP domain CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 PANTHER PTHR20863 2 74 8.2E-17 T 09-11-2016 CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 Gene3D G3DSA:1.10.1200.10 2 72 1.4E-23 T 09-11-2016 IPR009081 Phosphopantetheine binding ACP domain CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 72 2.0E-8 T 09-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 Hamap MF_01217 Acyl carrier protein [acpP]. 1 72 18.322 T 09-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 CLOSPO_RS14830 6b1ac9e98eedb14c1989b5eb17bd7caf 74 SUPERFAMILY SSF47336 2 73 3.01E-18 T 09-11-2016 IPR009081 Phosphopantetheine binding ACP domain CLOSPO_RS17075 c2ff3bd18ccfe43b67777896b75a4eb5 208 Gene3D G3DSA:3.40.50.150 37 185 4.2E-35 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17075 c2ff3bd18ccfe43b67777896b75a4eb5 208 PANTHER PTHR10108 5 181 8.2E-26 T 09-11-2016 CLOSPO_RS17075 c2ff3bd18ccfe43b67777896b75a4eb5 208 SUPERFAMILY SSF53335 5 183 8.21E-35 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17075 c2ff3bd18ccfe43b67777896b75a4eb5 208 Pfam PF08241 Methyltransferase domain 43 138 1.9E-17 T 09-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CLOSPO_RS18545 051f5924367434c94496e16b5a527085 187 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 56 78 - T 09-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOSPO_RS18545 051f5924367434c94496e16b5a527085 187 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 78 2.7E-13 T 09-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOSPO_RS18545 051f5924367434c94496e16b5a527085 187 PIRSF PIRSF000847 2 187 2.2E-23 T 09-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 CLOSPO_RS17380 61fd3cf55dad8ecffadacd04953daf3f 113 PANTHER PTHR34535 2 110 1.6E-41 T 09-11-2016 CLOSPO_RS17380 61fd3cf55dad8ecffadacd04953daf3f 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2 110 1.7E-25 T 09-11-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 CLOSPO_RS17380 61fd3cf55dad8ecffadacd04953daf3f 113 PIRSF PIRSF004761 1 113 3.7E-24 T 09-11-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 CLOSPO_RS17380 61fd3cf55dad8ecffadacd04953daf3f 113 PANTHER PTHR34535:SF2 2 110 1.6E-41 T 09-11-2016 CLOSPO_RS14295 9689abe2c9486bbed113313eebfa0751 402 Pfam PF02687 FtsX-like permease family 283 395 9.5E-23 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS14295 9689abe2c9486bbed113313eebfa0751 402 PANTHER PTHR30572 1 402 5.8E-94 T 09-11-2016 CLOSPO_RS14295 9689abe2c9486bbed113313eebfa0751 402 Pfam PF12704 MacB-like periplasmic core domain 21 237 3.6E-33 T 09-11-2016 IPR025857 MacB-like periplasmic core domain CLOSPO_RS13100 8c5689cc39e18e86237a3553c78518aa 433 PANTHER PTHR11119 10 429 1.8E-109 T 09-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS13100 8c5689cc39e18e86237a3553c78518aa 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 346 366 - T 09-11-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 CLOSPO_RS13100 8c5689cc39e18e86237a3553c78518aa 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 428 1.1E-120 T 09-11-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 CLOSPO_RS13100 8c5689cc39e18e86237a3553c78518aa 433 TIGRFAM TIGR03173 pbuX: xanthine permease 26 430 1.8E-148 T 09-11-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CLOSPO_RS13100 8c5689cc39e18e86237a3553c78518aa 433 Pfam PF00860 Permease family 23 398 2.9E-96 T 09-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS13120 f71a559169ad9254d6c53fe548d5d16d 345 PANTHER PTHR30535 54 345 7.4E-55 T 09-11-2016 CLOSPO_RS13120 f71a559169ad9254d6c53fe548d5d16d 345 Gene3D G3DSA:3.40.50.1980 66 188 2.0E-13 T 09-11-2016 CLOSPO_RS13120 f71a559169ad9254d6c53fe548d5d16d 345 SUPERFAMILY SSF53807 67 342 3.26E-42 T 09-11-2016 CLOSPO_RS13120 f71a559169ad9254d6c53fe548d5d16d 345 PANTHER PTHR30535:SF5 54 345 7.4E-55 T 09-11-2016 CLOSPO_RS13120 f71a559169ad9254d6c53fe548d5d16d 345 Gene3D G3DSA:3.40.50.1980 191 343 1.8E-25 T 09-11-2016 CLOSPO_RS13120 f71a559169ad9254d6c53fe548d5d16d 345 Pfam PF01497 Periplasmic binding protein 76 315 4.7E-26 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS14630 dd51bfa64132b5824b46c0ac6cee7a9e 81 Pfam PF11823 Protein of unknown function (DUF3343) 3 71 6.2E-23 T 09-11-2016 IPR021778 Protein of unknown function DUF3343 CLOSPO_RS13015 382f42fe1ae34cee42d0526f4f6a03b8 44 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 6 42 2.8E-13 T 09-11-2016 IPR009229 Staphylococcal AgrD CLOSPO_RS17675 79e2ec6c204c96967adbef2fdb9770a0 209 SUPERFAMILY SSF55469 4 203 1.02E-47 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS17675 79e2ec6c204c96967adbef2fdb9770a0 209 Pfam PF00881 Nitroreductase family 8 184 5.1E-25 T 09-11-2016 IPR029479 Nitroreductase CLOSPO_RS17675 79e2ec6c204c96967adbef2fdb9770a0 209 PANTHER PTHR23026:SF108 1 209 1.1E-132 T 09-11-2016 CLOSPO_RS17675 79e2ec6c204c96967adbef2fdb9770a0 209 Gene3D G3DSA:3.40.109.10 2 205 4.2E-60 T 09-11-2016 IPR000415 Nitroreductase-like GO:0016491 CLOSPO_RS17675 79e2ec6c204c96967adbef2fdb9770a0 209 PANTHER PTHR23026 1 209 1.1E-132 T 09-11-2016 CLOSPO_RS13810 7e53d828bcaabe9817d850b7aff95fde 228 Pfam PF00149 Calcineurin-like phosphoesterase 4 195 2.5E-13 T 09-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CLOSPO_RS13810 7e53d828bcaabe9817d850b7aff95fde 228 PIRSF PIRSF033094 1 228 3.8E-98 T 09-11-2016 IPR014578 Predicted phosphoesterase, CT488 type CLOSPO_RS13810 7e53d828bcaabe9817d850b7aff95fde 228 SUPERFAMILY SSF56300 3 218 5.43E-27 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS13810 7e53d828bcaabe9817d850b7aff95fde 228 Gene3D G3DSA:3.60.21.10 159 227 3.7E-52 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS13810 7e53d828bcaabe9817d850b7aff95fde 228 Gene3D G3DSA:3.60.21.10 3 121 3.7E-52 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS14550 47bcd1f1d295da6f8d28b3e5105facf9 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 14.406 T 09-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14550 47bcd1f1d295da6f8d28b3e5105facf9 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 09-11-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14550 47bcd1f1d295da6f8d28b3e5105facf9 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 4 44 4.1E-18 T 09-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14550 47bcd1f1d295da6f8d28b3e5105facf9 44 PANTHER PTHR14503 1 44 2.1E-14 T 09-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14550 47bcd1f1d295da6f8d28b3e5105facf9 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 31 9.0E-10 T 09-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14550 47bcd1f1d295da6f8d28b3e5105facf9 44 Pfam PF00468 Ribosomal protein L34 2 44 7.0E-21 T 09-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 PANTHER PTHR37293 2 327 1.0E-154 T 09-11-2016 CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 218 278 2.0E-16 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 122 192 3.0E-17 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 SUPERFAMILY SSF158499 121 187 9.29E-18 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 SUPERFAMILY SSF158499 211 274 7.72E-16 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 PIRSF PIRSF033722 1 328 9.8E-150 T 09-11-2016 IPR017019 Predicted DNA replication protein, bacterial CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 Pfam PF07261 Replication initiation and membrane attachment 123 195 3.1E-25 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 Pfam PF07261 Replication initiation and membrane attachment 223 278 4.5E-14 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 PANTHER PTHR37293:SF1 2 327 1.0E-154 T 09-11-2016 CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 Gene3D G3DSA:1.10.10.630 117 192 1.5E-24 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS14805 f1912d6111742707dcdfbd8d1e65061b 328 Gene3D G3DSA:1.10.10.630 206 278 8.3E-19 T 09-11-2016 IPR006343 Replication protein, DnaD/DnaB domain CLOSPO_RS18190 105267e1b82ddc2b9aff103e10327d5e 254 Pfam PF01226 Formate/nitrite transporter 10 249 4.0E-67 T 09-11-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CLOSPO_RS18190 105267e1b82ddc2b9aff103e10327d5e 254 PANTHER PTHR30520:SF5 1 254 3.4E-104 T 09-11-2016 CLOSPO_RS18190 105267e1b82ddc2b9aff103e10327d5e 254 Gene3D G3DSA:1.20.1080.10 25 253 4.1E-68 T 09-11-2016 IPR023271 Aquaporin-like CLOSPO_RS18190 105267e1b82ddc2b9aff103e10327d5e 254 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 09-11-2016 IPR024002 Formate/nitrite transporter, conserved site CLOSPO_RS18190 105267e1b82ddc2b9aff103e10327d5e 254 PANTHER PTHR30520 1 254 3.4E-104 T 09-11-2016 CLOSPO_RS18190 105267e1b82ddc2b9aff103e10327d5e 254 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 159 169 - T 09-11-2016 IPR024002 Formate/nitrite transporter, conserved site CLOSPO_RS18715 8a5c5683b48d0ada18be905ce0d73b2d 200 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 13 196 5.1E-40 T 09-11-2016 IPR011733 Conserved hypothetical CHP02185, integral membrane CLOSPO_RS18715 8a5c5683b48d0ada18be905ce0d73b2d 200 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 11 196 7.3E-34 T 09-11-2016 IPR011733 Conserved hypothetical CHP02185, integral membrane CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Gene3D G3DSA:1.25.40.10 182 248 3.7E-7 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Gene3D G3DSA:3.90.640.20 732 823 3.0E-25 T 09-11-2016 IPR021729 Domain of unknown function DUF3298 CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF11738 Protein of unknown function (DUF3298) 732 807 4.5E-21 T 09-11-2016 IPR021729 Domain of unknown function DUF3298 CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF14903 WG containing repeat 490 508 2.8E-4 T 09-11-2016 IPR032774 WG containing repeat CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF14903 WG containing repeat 306 334 9.9E-5 T 09-11-2016 IPR032774 WG containing repeat CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF14903 WG containing repeat 271 304 1.9E-7 T 09-11-2016 IPR032774 WG containing repeat CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF14903 WG containing repeat 381 412 1.9E-8 T 09-11-2016 IPR032774 WG containing repeat CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF14903 WG containing repeat 452 480 4.9E-9 T 09-11-2016 IPR032774 WG containing repeat CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Pfam PF14903 WG containing repeat 416 452 0.015 T 09-11-2016 IPR032774 WG containing repeat CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 Gene3D G3DSA:3.30.565.40 627 728 1.1E-9 T 09-11-2016 IPR025303 Domain of unknown function DUF4163 CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 SUPERFAMILY SSF48452 179 232 5.96E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS18425 3eb2b3223e17e813a992396f30a58816 824 PANTHER PTHR37841 213 824 9.3E-120 T 09-11-2016 CLOSPO_RS12700 67df5ca30c3cbf9d790d4272146352d9 175 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 11 174 4.0E-54 T 09-11-2016 IPR014247 Sporulation lipoprotein YhcN/YlaJ CLOSPO_RS12700 67df5ca30c3cbf9d790d4272146352d9 175 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 34 172 2.9E-25 T 09-11-2016 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CLOSPO_RS17200 03962ee2d64076eecc105bb9af0712bb 66 Pfam PF13783 Domain of unknown function (DUF4177) 3 62 7.4E-9 T 09-11-2016 IPR025234 Protein of unknown function DUF4177 CLOSPO_RS16175 9ed34fb1d92cf2e874bdfd7df3c8daa4 145 Pfam PF13673 Acetyltransferase (GNAT) domain 37 135 1.6E-10 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS16175 9ed34fb1d92cf2e874bdfd7df3c8daa4 145 Gene3D G3DSA:3.40.630.30 2 134 4.4E-21 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16175 9ed34fb1d92cf2e874bdfd7df3c8daa4 145 SUPERFAMILY SSF55729 2 139 3.44E-22 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS15485 c76b88280daa0f6e6c6922b16c9d0dba 216 SUPERFAMILY SSF48452 82 212 1.86E-12 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS15485 c76b88280daa0f6e6c6922b16c9d0dba 216 Pfam PF07719 Tetratricopeptide repeat 127 155 4.8E-5 T 09-11-2016 IPR013105 Tetratricopeptide repeat 2 CLOSPO_RS15485 c76b88280daa0f6e6c6922b16c9d0dba 216 Gene3D G3DSA:1.25.40.10 107 211 5.5E-13 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS15485 c76b88280daa0f6e6c6922b16c9d0dba 216 SMART SM00028 168 202 57.0 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS15485 c76b88280daa0f6e6c6922b16c9d0dba 216 SMART SM00028 127 160 9.0E-5 T 09-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 PANTHER PTHR11019 45 252 4.5E-42 T 09-11-2016 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 SUPERFAMILY SSF46689 198 248 8.06E-13 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 PANTHER PTHR11019:SF141 45 252 4.5E-42 T 09-11-2016 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 SUPERFAMILY SSF46689 145 194 8.24E-7 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 Gene3D G3DSA:1.10.10.60 199 248 5.4E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 Pfam PF12833 Helix-turn-helix domain 169 246 6.1E-18 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 Gene3D G3DSA:1.10.10.60 139 198 5.1E-15 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 214 229 5.3E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 229 245 5.3E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 SMART SM00342 162 245 2.7E-28 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS18685 0e2151604ac59cba2360e5a457546efe 252 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 199 241 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16285 8d39b8b64272dd40c4466decdbd7ba9c 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 3.2E-15 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS16285 8d39b8b64272dd40c4466decdbd7ba9c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.8E-10 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS16285 8d39b8b64272dd40c4466decdbd7ba9c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.8E-10 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS16285 8d39b8b64272dd40c4466decdbd7ba9c 197 Gene3D G3DSA:1.10.357.10 2 184 4.1E-24 T 09-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CLOSPO_RS16285 8d39b8b64272dd40c4466decdbd7ba9c 197 PANTHER PTHR30328 1 195 1.8E-14 T 09-11-2016 CLOSPO_RS16285 8d39b8b64272dd40c4466decdbd7ba9c 197 SUPERFAMILY SSF46689 6 66 2.6E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16055 7f37beb0fe5bda3e2c770f87f4b451cb 353 PANTHER PTHR30040:SF2 1 348 5.1E-99 T 09-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 CLOSPO_RS16055 7f37beb0fe5bda3e2c770f87f4b451cb 353 PANTHER PTHR30040 1 348 5.1E-99 T 09-11-2016 CLOSPO_RS16055 7f37beb0fe5bda3e2c770f87f4b451cb 353 Pfam PF02424 ApbE family 43 324 1.0E-75 T 09-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 CLOSPO_RS16055 7f37beb0fe5bda3e2c770f87f4b451cb 353 PIRSF PIRSF006268 1 346 7.3E-103 T 09-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 CLOSPO_RS16055 7f37beb0fe5bda3e2c770f87f4b451cb 353 SUPERFAMILY SSF143631 38 341 1.18E-84 T 09-11-2016 IPR003374 ApbE-like domain CLOSPO_RS13315 72d6775e51b369276ece950dbde75299 653 Pfam PF00144 Beta-lactamase 55 376 3.5E-61 T 09-11-2016 IPR001466 Beta-lactamase-related CLOSPO_RS13315 72d6775e51b369276ece950dbde75299 653 Gene3D G3DSA:3.40.710.10 46 376 1.5E-74 T 09-11-2016 IPR012338 Beta-lactamase/transpeptidase-like CLOSPO_RS13315 72d6775e51b369276ece950dbde75299 653 PANTHER PTHR22935 47 373 8.0E-72 T 09-11-2016 CLOSPO_RS13315 72d6775e51b369276ece950dbde75299 653 SUPERFAMILY SSF56601 53 387 5.51E-74 T 09-11-2016 IPR012338 Beta-lactamase/transpeptidase-like CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 09-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 SUPERFAMILY SSF51230 3 125 1.31E-40 T 09-11-2016 IPR011053 Single hybrid motif CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 5 125 2.6E-43 T 09-11-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 Gene3D G3DSA:2.40.50.100 6 125 7.9E-47 T 09-11-2016 CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 Pfam PF01597 Glycine cleavage H-protein 7 125 2.1E-42 T 09-11-2016 IPR002930 Glycine cleavage system H-protein CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 27.189 T 09-11-2016 IPR002930 Glycine cleavage system H-protein CLOSPO_RS16950 c9f363c0fb140acfd6c3df8f91360afd 130 PANTHER PTHR11715 1 130 8.1E-61 T 09-11-2016 IPR002930 Glycine cleavage system H-protein CLOSPO_RS13730 049fa9e81242959ae1e81f092067d62c 222 Gene3D G3DSA:3.30.240.20 77 151 7.0E-29 T 09-11-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CLOSPO_RS13730 049fa9e81242959ae1e81f092067d62c 222 Gene3D G3DSA:3.30.240.20 166 222 7.2E-18 T 09-11-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CLOSPO_RS13730 049fa9e81242959ae1e81f092067d62c 222 PANTHER PTHR34582 1 222 1.5E-112 T 09-11-2016 CLOSPO_RS13730 049fa9e81242959ae1e81f092067d62c 222 PANTHER PTHR34582:SF4 1 222 1.5E-112 T 09-11-2016 CLOSPO_RS13730 049fa9e81242959ae1e81f092067d62c 222 Pfam PF04239 Protein of unknown function (DUF421) 86 201 2.5E-37 T 09-11-2016 IPR007353 Protein of unknown function DUF421 CLOSPO_RS15525 5b7f47238c7bf1d948f24d03824bcdfc 310 PANTHER PTHR14226 6 307 7.7E-126 T 09-11-2016 CLOSPO_RS15525 5b7f47238c7bf1d948f24d03824bcdfc 310 SUPERFAMILY SSF52151 6 303 1.94E-37 T 09-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CLOSPO_RS15525 5b7f47238c7bf1d948f24d03824bcdfc 310 Pfam PF01734 Patatin-like phospholipase 6 198 4.0E-24 T 09-11-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CLOSPO_RS15525 5b7f47238c7bf1d948f24d03824bcdfc 310 PANTHER PTHR14226:SF28 6 307 7.7E-126 T 09-11-2016 CLOSPO_RS15525 5b7f47238c7bf1d948f24d03824bcdfc 310 Gene3D G3DSA:3.40.1090.10 7 196 9.1E-19 T 09-11-2016 CLOSPO_RS09850 5b766aa05e694d192f4a78f08a566a85 110 Pfam PF01628 HrcA protein C terminal domain 2 110 5.4E-21 T 09-11-2016 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CLOSPO_RS09850 5b766aa05e694d192f4a78f08a566a85 110 SUPERFAMILY SSF55781 2 109 2.75E-12 T 09-11-2016 IPR029016 GAF domain-like CLOSPO_RS09850 5b766aa05e694d192f4a78f08a566a85 110 PANTHER PTHR34824 1 110 9.5E-15 T 09-11-2016 CLOSPO_RS09850 5b766aa05e694d192f4a78f08a566a85 110 Gene3D G3DSA:3.30.450.40 18 110 4.2E-17 T 09-11-2016 IPR029016 GAF domain-like CLOSPO_RS16640 b6e22ce75c9f2573607e18c1ece54698 228 Pfam PF08713 DNA alkylation repair enzyme 6 194 1.1E-16 T 09-11-2016 IPR014825 DNA alkylation repair enzyme CLOSPO_RS16640 b6e22ce75c9f2573607e18c1ece54698 228 SUPERFAMILY SSF48371 9 208 2.48E-44 T 09-11-2016 IPR016024 Armadillo-type fold GO:0005488 CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 SUPERFAMILY SSF46785 152 221 2.72E-11 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 Pfam PF13545 Crp-like helix-turn-helix domain 154 220 8.0E-12 T 09-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 PANTHER PTHR24567:SF26 13 228 1.5E-91 T 09-11-2016 CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 Pfam PF00027 Cyclic nucleotide-binding domain 35 117 1.6E-10 T 09-11-2016 IPR000595 Cyclic nucleotide-binding domain CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 SUPERFAMILY SSF51206 25 139 1.96E-24 T 09-11-2016 IPR018490 Cyclic nucleotide-binding-like CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 PANTHER PTHR24567 13 228 1.5E-91 T 09-11-2016 CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 Gene3D G3DSA:2.60.120.10 25 141 6.7E-21 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS18565 00666589dfb894d0fedffe8a3777f5ac 229 Gene3D G3DSA:1.10.10.10 157 221 2.9E-13 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 PANTHER PTHR23417:SF14 1 215 3.5E-59 T 09-11-2016 CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 Gene3D G3DSA:3.40.50.150 35 182 1.8E-14 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 Pfam PF02390 Putative methyltransferase 38 210 2.8E-40 T 09-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 SUPERFAMILY SSF53335 29 214 8.22E-29 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 25 209 5.3E-46 T 09-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 217 25.805 T 09-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 CLOSPO_RS15845 ca0b9df86660246fedb2037445d9e80d 217 PANTHER PTHR23417 1 215 3.5E-59 T 09-11-2016 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 PANTHER PTHR26402 5 229 2.5E-120 T 09-11-2016 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 PANTHER PTHR26402:SF614 5 229 2.5E-120 T 09-11-2016 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 SMART SM00448 5 115 7.2E-47 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 SMART SM00862 153 229 4.0E-27 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 SUPERFAMILY SSF46894 134 229 1.56E-29 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 Gene3D G3DSA:1.10.10.10 134 230 3.3E-33 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 1.4E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 Pfam PF00072 Response regulator receiver domain 7 116 6.9E-31 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 Gene3D G3DSA:3.40.50.2300 3 123 1.2E-43 T 09-11-2016 CLOSPO_RS18675 f4f5cea5608a0af3116ec9225cf43f1e 233 SUPERFAMILY SSF52172 5 124 1.34E-42 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS18455 2a119b4b0fd7c6f357e2fa90ba1ef7a1 507 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 4 502 2.0E-137 T 09-11-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CLOSPO_RS18455 2a119b4b0fd7c6f357e2fa90ba1ef7a1 507 Pfam PF02652 L-lactate permease 7 500 8.2E-142 T 09-11-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CLOSPO_RS18455 2a119b4b0fd7c6f357e2fa90ba1ef7a1 507 PANTHER PTHR30003:SF3 1 507 1.7E-290 T 09-11-2016 CLOSPO_RS18455 2a119b4b0fd7c6f357e2fa90ba1ef7a1 507 PANTHER PTHR30003 1 507 1.7E-290 T 09-11-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CLOSPO_RS14705 d90022fd35314de289133bd07da68ae0 71 Pfam PF11213 Protein of unknown function (DUF3006) 3 69 1.1E-19 T 09-11-2016 IPR021377 Protein of unknown function DUF3006 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 PANTHER PTHR42208:SF1 101 331 2.7E-29 T 09-11-2016 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 111 303 1.5E-51 T 09-11-2016 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 SUPERFAMILY SSF55008 5 70 1.57E-15 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 Gene3D G3DSA:3.30.70.100 4 69 3.6E-16 T 09-11-2016 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 Pfam PF00403 Heavy-metal-associated domain 8 67 2.5E-11 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 PANTHER PTHR42208 101 331 2.7E-29 T 09-11-2016 CLOSPO_RS18660 bc750252182b43724f082d46639a1ea6 601 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 09-11-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CLOSPO_RS17250 c81b2892ef16567a5535bdd1b74c3220 252 SUPERFAMILY SSF53335 14 217 1.19E-30 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17250 c81b2892ef16567a5535bdd1b74c3220 252 PANTHER PTHR10108 180 213 6.6E-23 T 09-11-2016 CLOSPO_RS17250 c81b2892ef16567a5535bdd1b74c3220 252 PANTHER PTHR10108 4 153 6.6E-23 T 09-11-2016 CLOSPO_RS17250 c81b2892ef16567a5535bdd1b74c3220 252 Pfam PF13649 Methyltransferase domain 43 139 3.8E-18 T 09-11-2016 CLOSPO_RS17250 c81b2892ef16567a5535bdd1b74c3220 252 Gene3D G3DSA:3.40.50.150 28 218 3.3E-28 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16910 f1e7c2e63408dfc831b3d6f2c47c5dd6 216 PANTHER PTHR23416 64 216 3.3E-63 T 09-11-2016 CLOSPO_RS16910 f1e7c2e63408dfc831b3d6f2c47c5dd6 216 SUPERFAMILY SSF51161 28 207 6.38E-44 T 09-11-2016 IPR011004 Trimeric LpxA-like CLOSPO_RS16910 f1e7c2e63408dfc831b3d6f2c47c5dd6 216 Gene3D G3DSA:2.160.10.10 20 213 1.9E-53 T 09-11-2016 CLOSPO_RS16910 f1e7c2e63408dfc831b3d6f2c47c5dd6 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 125 153 - T 09-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 CLOSPO_RS16910 f1e7c2e63408dfc831b3d6f2c47c5dd6 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 151 5.9E-10 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS16910 f1e7c2e63408dfc831b3d6f2c47c5dd6 216 PANTHER PTHR23416:SF59 64 216 3.3E-63 T 09-11-2016 CLOSPO_RS12675 277ff8419234f102d1c504296263c7d9 144 Gene3D G3DSA:3.90.10.10 72 135 3.4E-5 T 09-11-2016 CLOSPO_RS12675 277ff8419234f102d1c504296263c7d9 144 Pfam PF01475 Ferric uptake regulator family 10 126 3.8E-19 T 09-11-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CLOSPO_RS12675 277ff8419234f102d1c504296263c7d9 144 PANTHER PTHR33202 4 135 1.6E-26 T 09-11-2016 CLOSPO_RS12675 277ff8419234f102d1c504296263c7d9 144 SUPERFAMILY SSF46785 4 132 6.22E-27 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS12675 277ff8419234f102d1c504296263c7d9 144 Gene3D G3DSA:1.10.10.10 4 71 8.3E-19 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 SUPERFAMILY SSF55604 448 521 7.45E-22 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 Pfam PF02378 Phosphotransferase system, EIIC 14 348 3.0E-59 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 PANTHER PTHR30009 6 523 0.0 T 09-11-2016 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 407 507 1.5E-20 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 Gene3D G3DSA:3.30.1360.60 446 522 1.3E-26 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 PANTHER PTHR30009:SF5 6 523 0.0 T 09-11-2016 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 461 478 - T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS13245 351f3e17e98cbfa501e590d809b52b07 523 Pfam PF00367 phosphotransferase system, EIIB 452 483 3.3E-14 T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS18080 8b0b939e6e3d0011922521f798283adc 177 Pfam PF04229 GrpB protein 10 168 3.5E-54 T 09-11-2016 IPR007344 GrpB/Dephospho-CoA kinase CLOSPO_RS18080 8b0b939e6e3d0011922521f798283adc 177 PANTHER PTHR34822 7 173 8.2E-59 T 09-11-2016 CLOSPO_RS18080 8b0b939e6e3d0011922521f798283adc 177 SUPERFAMILY SSF81301 11 175 1.63E-56 T 09-11-2016 CLOSPO_RS18080 8b0b939e6e3d0011922521f798283adc 177 Gene3D G3DSA:3.30.460.10 7 175 5.4E-62 T 09-11-2016 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 Pfam PF03060 Nitronate monooxygenase 83 299 9.5E-57 T 09-11-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 Pfam PF03060 Nitronate monooxygenase 5 81 2.5E-21 T 09-11-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 PANTHER PTHR32332 3 305 7.4E-134 T 09-11-2016 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 Gene3D G3DSA:3.20.20.70 8 295 2.9E-79 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 SUPERFAMILY SSF51412 8 304 6.72E-81 T 09-11-2016 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 PANTHER PTHR32332:SF20 3 305 7.4E-134 T 09-11-2016 CLOSPO_RS14835 b0902650bc79454af8045117db1e5102 308 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 6 302 1.7E-154 T 09-11-2016 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 SMART SM00382 36 215 2.8E-6 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 SMART SM00382 296 482 2.5E-13 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 PANTHER PTHR24220:SF435 11 386 7.7E-79 T 09-11-2016 CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 SUPERFAMILY SSF52540 262 474 4.78E-53 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 Gene3D G3DSA:3.40.50.300 267 473 7.5E-52 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 Gene3D G3DSA:3.40.50.300 7 238 4.0E-55 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 Pfam PF00005 ABC transporter 288 425 1.1E-28 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 Pfam PF00005 ABC transporter 27 178 4.5E-25 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 PANTHER PTHR24220 11 386 7.7E-79 T 09-11-2016 CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 SUPERFAMILY SSF52540 7 238 1.08E-49 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18725 46b9d90c9a59bd85e4fa6cd7a09e11ab 499 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 128 273 9.2E-55 T 09-11-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 439 156.276 T 09-11-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 366 377 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 SUPERFAMILY SSF142019 87 293 3.66E-63 T 09-11-2016 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 3 434 8.0E-173 T 09-11-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 Gene3D G3DSA:1.10.1060.10 315 438 2.1E-14 T 09-11-2016 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 PANTHER PTHR11780:SF1 1 439 2.5E-197 T 09-11-2016 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 Pfam PF13187 4Fe-4S dicluster domain 366 418 4.4E-7 T 09-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 PANTHER PTHR11780 1 439 2.5E-197 T 09-11-2016 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 Pfam PF10531 SLBB domain 286 334 6.1E-15 T 09-11-2016 IPR019554 Soluble ligand binding domain CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 SUPERFAMILY SSF46548 324 435 1.57E-20 T 09-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 104 3.1E-39 T 09-11-2016 IPR026902 RnfC Barrel sandwich hybrid domain CLOSPO_RS12825 5caf23466abc798f419893def9bee4c7 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 405 416 - T 09-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOSPO_RS18740 aad1d6bf73e523b48493cbcf5fba69f7 457 SUPERFAMILY SSF55874 318 446 3.01E-8 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18740 aad1d6bf73e523b48493cbcf5fba69f7 457 Gene3D G3DSA:3.30.565.10 318 447 7.1E-5 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS18740 aad1d6bf73e523b48493cbcf5fba69f7 457 PANTHER PTHR40448 2 457 4.0E-120 T 09-11-2016 CLOSPO_RS18740 aad1d6bf73e523b48493cbcf5fba69f7 457 PANTHER PTHR40448:SF1 2 457 4.0E-120 T 09-11-2016 CLOSPO_RS18740 aad1d6bf73e523b48493cbcf5fba69f7 457 Pfam PF14501 GHKL domain 350 454 8.6E-24 T 09-11-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain CLOSPO_RS16395 bc8b41a0d299da6896d3b1ab58613d29 208 SUPERFAMILY SSF48452 178 192 2.2E-7 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16395 bc8b41a0d299da6896d3b1ab58613d29 208 SUPERFAMILY SSF48452 46 116 2.2E-7 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16395 bc8b41a0d299da6896d3b1ab58613d29 208 Pfam PF07532 Bacterial Ig-like domain (group 4) 131 185 4.8E-11 T 09-11-2016 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CLOSPO_RS16395 bc8b41a0d299da6896d3b1ab58613d29 208 Gene3D G3DSA:1.25.40.10 49 115 4.6E-6 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 Hamap MF_00550 Peptidase T [pepT]. 1 405 58.885 T 09-11-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 09-11-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 Pfam PF07687 Peptidase dimerisation domain 208 307 2.2E-10 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 PANTHER PTHR11014:SF3 2 91 2.2E-190 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 PANTHER PTHR11014:SF3 132 408 2.2E-190 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 SUPERFAMILY SSF53187 323 407 2.88E-78 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 SUPERFAMILY SSF53187 1 211 2.88E-78 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 407 3.9E-178 T 09-11-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 Pfam PF01546 Peptidase family M20/M25/M40 140 402 1.4E-10 T 09-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 PANTHER PTHR11014 132 408 2.2E-190 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 Gene3D G3DSA:3.30.70.360 211 320 2.7E-46 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 Gene3D G3DSA:3.40.630.10 323 407 5.3E-120 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 Gene3D G3DSA:3.40.630.10 1 210 5.3E-120 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 PANTHER PTHR11014 2 91 2.2E-190 T 09-11-2016 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 PIRSF PIRSF037215 1 408 9.3E-189 T 09-11-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 139 178 - T 09-11-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CLOSPO_RS15520 1a6ab72aff0b54c00ead6172f2ffc6f8 408 SUPERFAMILY SSF55031 210 321 8.89E-40 T 09-11-2016 IPR011650 Peptidase M20, dimerisation domain CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 SUPERFAMILY SSF46689 184 234 9.86E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 Pfam PF12833 Helix-turn-helix domain 154 232 1.2E-17 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 SUPERFAMILY SSF51215 12 69 1.02E-8 T 09-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 SUPERFAMILY SSF46689 136 182 2.28E-6 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 PANTHER PTHR11019 1 239 8.4E-99 T 09-11-2016 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 Pfam PF02311 AraC-like ligand binding domain 9 66 9.4E-7 T 09-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 185 227 - T 09-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 Gene3D G3DSA:1.10.10.60 185 235 4.4E-15 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 PANTHER PTHR11019:SF136 1 239 8.4E-99 T 09-11-2016 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 Gene3D G3DSA:2.60.120.280 12 68 1.3E-6 T 09-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 SMART SM00342 148 231 1.4E-20 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16495 50e782e54bb8e07d1c884faab31f29d7 241 Gene3D G3DSA:1.10.10.60 132 184 2.3E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17655 4c20eb2a93b4dfc56c7653e6ee8f84dd 217 PANTHER PTHR14136:SF13 10 201 1.9E-93 T 09-11-2016 CLOSPO_RS17655 4c20eb2a93b4dfc56c7653e6ee8f84dd 217 Pfam PF13599 Pentapeptide repeats (9 copies) 95 166 4.0E-11 T 09-11-2016 IPR001646 Pentapeptide repeat CLOSPO_RS17655 4c20eb2a93b4dfc56c7653e6ee8f84dd 217 PANTHER PTHR14136 10 201 1.9E-93 T 09-11-2016 CLOSPO_RS17655 4c20eb2a93b4dfc56c7653e6ee8f84dd 217 SUPERFAMILY SSF141571 37 215 2.75E-39 T 09-11-2016 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 SMART SM00347 21 121 8.2E-12 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 PANTHER PTHR33164 1 145 4.2E-18 T 09-11-2016 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 8.5E-7 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 8.5E-7 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 8.5E-7 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 8.5E-7 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 Pfam PF01047 MarR family 29 85 9.7E-11 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 Gene3D G3DSA:1.10.10.10 5 138 1.3E-26 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17230 5e6e839b2a80fe00e5739337e43f85e6 200 SUPERFAMILY SSF46785 4 138 3.64E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16490 430595f056d87c049d52d881f8a03e4b 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 9.6E-48 T 09-11-2016 IPR008231 Probable chaperone CsaA CLOSPO_RS16490 430595f056d87c049d52d881f8a03e4b 109 SUPERFAMILY SSF50249 1 108 1.52E-30 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS16490 430595f056d87c049d52d881f8a03e4b 109 PANTHER PTHR11586 2 108 1.8E-37 T 09-11-2016 CLOSPO_RS16490 430595f056d87c049d52d881f8a03e4b 109 Pfam PF01588 Putative tRNA binding domain 12 107 9.5E-16 T 09-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 CLOSPO_RS16490 430595f056d87c049d52d881f8a03e4b 109 Gene3D G3DSA:2.40.50.140 2 108 1.8E-34 T 09-11-2016 IPR012340 Nucleic acid-binding, OB-fold CLOSPO_RS18870 8d003e031d940f8c425ba88c0b3e290b 122 Pfam PF07892 Protein of unknown function (DUF1667) 35 116 5.5E-33 T 09-11-2016 IPR012460 Protein of unknown function DUF1667 CLOSPO_RS18870 8d003e031d940f8c425ba88c0b3e290b 122 Gene3D G3DSA:2.20.25.90 7 33 5.1E-4 T 09-11-2016 CLOSPO_RS18870 8d003e031d940f8c425ba88c0b3e290b 122 PANTHER PTHR39450 3 122 4.1E-56 T 09-11-2016 CLOSPO_RS18870 8d003e031d940f8c425ba88c0b3e290b 122 SUPERFAMILY SSF53706 6 53 5.65E-6 T 09-11-2016 CLOSPO_RS18870 8d003e031d940f8c425ba88c0b3e290b 122 SUPERFAMILY SSF160148 47 119 1.29E-24 T 09-11-2016 IPR012460 Protein of unknown function DUF1667 CLOSPO_RS18870 8d003e031d940f8c425ba88c0b3e290b 122 Gene3D G3DSA:3.10.530.10 47 116 2.5E-29 T 09-11-2016 IPR012460 Protein of unknown function DUF1667 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 8.6E-21 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 SMART SM00862 151 226 6.9E-18 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 SUPERFAMILY SSF52172 3 129 2.99E-35 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 Gene3D G3DSA:1.10.10.10 130 226 2.4E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 SUPERFAMILY SSF46894 127 226 3.68E-25 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 Pfam PF00072 Response regulator receiver domain 8 115 1.1E-24 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 PANTHER PTHR26402:SF519 5 224 7.2E-103 T 09-11-2016 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 PANTHER PTHR26402 5 224 7.2E-103 T 09-11-2016 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 Gene3D G3DSA:3.40.50.2300 3 129 3.5E-36 T 09-11-2016 CLOSPO_RS13420 003438a0951134872bb838dfe396de0a 227 SMART SM00448 5 115 9.4E-33 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16895 167d28ac0b4de3e498c7fbe28f0a9dbf 412 SUPERFAMILY SSF53807 10 409 2.71E-63 T 09-11-2016 CLOSPO_RS16895 167d28ac0b4de3e498c7fbe28f0a9dbf 412 PANTHER PTHR33712 3 412 1.3E-163 T 09-11-2016 CLOSPO_RS16895 167d28ac0b4de3e498c7fbe28f0a9dbf 412 Gene3D G3DSA:3.40.50.1980 14 149 3.2E-18 T 09-11-2016 CLOSPO_RS16895 167d28ac0b4de3e498c7fbe28f0a9dbf 412 Gene3D G3DSA:3.40.50.1980 152 257 9.3E-19 T 09-11-2016 CLOSPO_RS16895 167d28ac0b4de3e498c7fbe28f0a9dbf 412 PANTHER PTHR33712:SF2 3 412 1.3E-163 T 09-11-2016 CLOSPO_RS16895 167d28ac0b4de3e498c7fbe28f0a9dbf 412 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 14 406 1.2E-50 T 09-11-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 SUPERFAMILY SSF53901 4 332 1.61E-33 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 243 332 9.7E-19 T 09-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 PANTHER PTHR34069:SF2 1 332 3.9E-101 T 09-11-2016 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 Gene3D G3DSA:3.40.47.10 1 169 5.0E-32 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 PANTHER PTHR34069 1 332 3.9E-101 T 09-11-2016 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 188 5.5E-11 T 09-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 CLOSPO_RS17015 956a7c4434067f63f00789a677392a53 332 Gene3D G3DSA:3.40.47.10 170 331 1.3E-22 T 09-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 Gene3D G3DSA:3.30.200.20 3 94 1.2E-25 T 09-11-2016 CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 PANTHER PTHR39179 1 333 4.9E-142 T 09-11-2016 CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 PANTHER PTHR39179:SF1 1 333 4.9E-142 T 09-11-2016 CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 16 331 3.2E-96 T 09-11-2016 IPR014255 Spore coat protein CotS CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 Pfam PF01636 Phosphotransferase enzyme family 179 248 1.4E-11 T 09-11-2016 IPR002575 Aminoglycoside phosphotransferase CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 Gene3D G3DSA:3.90.1200.10 97 327 3.5E-66 T 09-11-2016 CLOSPO_RS14180 aa9ef79a01fe2e0d7c0347b28f6c5b98 336 SUPERFAMILY SSF56112 2 333 9.39E-52 T 09-11-2016 IPR011009 Protein kinase-like domain CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 SMART SM00448 1 115 4.1E-10 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 PANTHER PTHR26402:SF561 1 246 1.8E-64 T 09-11-2016 CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 PANTHER PTHR26402 1 246 1.8E-64 T 09-11-2016 CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 Pfam PF00072 Response regulator receiver domain 3 114 2.4E-18 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 Pfam PF08664 YcbB domain 146 264 1.3E-35 T 09-11-2016 IPR013972 YcbB domain CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 Gene3D G3DSA:1.10.10.10 141 226 9.4E-4 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 SUPERFAMILY SSF52172 1 125 1.32E-24 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS16440 07181bf4b9edb354144f37dee9be02bf 270 Gene3D G3DSA:3.40.50.2300 1 127 2.6E-25 T 09-11-2016 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 SUPERFAMILY SSF46785 263 337 8.4E-17 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 296 311 1.6E-6 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 264 279 1.6E-6 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 311 326 1.6E-6 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 Gene3D G3DSA:1.10.10.10 259 340 9.9E-17 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 Pfam PF01022 Bacterial regulatory protein, arsR family 269 310 7.8E-8 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 PANTHER PTHR33154 2 343 2.8E-243 T 09-11-2016 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 SMART SM00418 262 340 6.4E-12 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS16465 63b2a1bdbae1ac007248024e11a7e94d 343 PANTHER PTHR33154:SF1 2 343 2.8E-243 T 09-11-2016 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 302 1.7E-107 T 09-11-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 SUPERFAMILY SSF53686 1 299 1.2E-96 T 09-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 PANTHER PTHR10314:SF8 2 299 1.9E-131 T 09-11-2016 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 09-11-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 Gene3D G3DSA:3.40.50.1100 43 144 7.4E-37 T 09-11-2016 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 302 3.4E-109 T 09-11-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 Gene3D G3DSA:3.40.50.1100 150 301 6.2E-76 T 09-11-2016 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 Gene3D G3DSA:3.40.50.1100 2 42 6.2E-76 T 09-11-2016 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 PANTHER PTHR10314 2 299 1.9E-131 T 09-11-2016 CLOSPO_RS17060 a2b44aa9743103a64b6ce0d25d0a3917 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 291 3.8E-70 T 09-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 Pfam PF00137 ATP synthase subunit C 13 75 1.7E-18 T 09-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 76 4.9E-19 T 09-11-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 PANTHER PTHR10031 7 76 7.2E-20 T 09-11-2016 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 78 17.048 T 09-11-2016 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 Gene3D G3DSA:1.20.20.10 5 76 5.4E-27 T 09-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 SUPERFAMILY SSF81333 6 78 2.35E-21 T 09-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 41 62 - T 09-11-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 PRINTS PR00124 ATP synthase C subunit signature 51 76 4.3E-25 T 09-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 PRINTS PR00124 ATP synthase C subunit signature 13 32 4.3E-25 T 09-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13970 9ef1e653ff5818751e2e07b08e0b88d3 80 PRINTS PR00124 ATP synthase C subunit signature 34 49 4.3E-25 T 09-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 CLOSPO_RS13130 5a7413b6d658e8e44711b5126b459427 759 PANTHER PTHR33908:SF3 1 260 4.9E-36 T 09-11-2016 CLOSPO_RS13130 5a7413b6d658e8e44711b5126b459427 759 PANTHER PTHR33908 1 260 4.9E-36 T 09-11-2016 CLOSPO_RS13130 5a7413b6d658e8e44711b5126b459427 759 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 66 224 4.0E-45 T 09-11-2016 CLOSPO_RS14950 6e0d3d1a668f47b349d88becc397da42 498 PIRSF PIRSF028991 1 498 7.4E-180 T 09-11-2016 IPR016905 Glycyl radical enzyme, HI0521, predicted CLOSPO_RS14950 6e0d3d1a668f47b349d88becc397da42 498 TIGRFAM TIGR04040 glycyl_YjjI: glycine radical enzyme, YjjI family 3 495 5.2E-242 T 09-11-2016 IPR016905 Glycyl radical enzyme, HI0521, predicted CLOSPO_RS14950 6e0d3d1a668f47b349d88becc397da42 498 Pfam PF11230 Protein of unknown function (DUF3029) 13 495 2.3E-226 T 09-11-2016 IPR016905 Glycyl radical enzyme, HI0521, predicted CLOSPO_RS14950 6e0d3d1a668f47b349d88becc397da42 498 SUPERFAMILY SSF51998 5 470 2.41E-81 T 09-11-2016 CLOSPO_RS14950 6e0d3d1a668f47b349d88becc397da42 498 Gene3D G3DSA:3.20.70.20 78 464 4.7E-25 T 09-11-2016 CLOSPO_RS14415 b6a42427c88ce045e19a46495bd35823 363 PANTHER PTHR21666 220 357 9.3E-41 T 09-11-2016 CLOSPO_RS14415 b6a42427c88ce045e19a46495bd35823 363 SUPERFAMILY SSF57997 30 92 9.59E-7 T 09-11-2016 CLOSPO_RS14415 b6a42427c88ce045e19a46495bd35823 363 Gene3D G3DSA:3.90.1720.10 251 354 2.5E-45 T 09-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- CLOSPO_RS14415 b6a42427c88ce045e19a46495bd35823 363 SUPERFAMILY SSF54001 249 354 4.91E-43 T 09-11-2016 CLOSPO_RS14415 b6a42427c88ce045e19a46495bd35823 363 Pfam PF00877 NlpC/P60 family 266 357 1.2E-29 T 09-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 Gene3D G3DSA:3.40.50.10190 220 307 4.6E-13 T 09-11-2016 IPR001357 BRCT domain CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 SUPERFAMILY SSF53098 1 177 4.56E-40 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 PANTHER PTHR30231:SF10 1 268 1.9E-95 T 09-11-2016 CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 Pfam PF00929 Exonuclease 4 156 4.4E-22 T 09-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 SUPERFAMILY SSF52113 217 306 1.57E-9 T 09-11-2016 IPR001357 BRCT domain CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 SMART SM00479 2 166 2.1E-12 T 09-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 PANTHER PTHR30231 1 268 1.9E-95 T 09-11-2016 CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 Gene3D G3DSA:3.30.420.10 1 169 4.5E-41 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS13345 d308c401077017d801ddcdf4aa1e4c20 309 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 217 301 8.4E-7 T 09-11-2016 IPR001357 BRCT domain CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 PANTHER PTHR31377:SF0 4 206 1.6E-99 T 09-11-2016 CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 PANTHER PTHR31377:SF0 227 408 1.6E-99 T 09-11-2016 CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 PANTHER PTHR31377 4 206 1.6E-99 T 09-11-2016 CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 PANTHER PTHR31377 227 408 1.6E-99 T 09-11-2016 CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 Gene3D G3DSA:3.75.10.10 4 408 3.8E-84 T 09-11-2016 CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 SUPERFAMILY SSF55909 4 408 3.93E-69 T 09-11-2016 CLOSPO_RS17825 1010f30153b6874adf3e9f872a8069aa 410 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 7 407 2.8E-62 T 09-11-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PANTHER PTHR10283:SF67 1 418 7.1E-162 T 09-11-2016 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PRINTS PR00758 Arsenical pump membrane protein signature 270 294 4.3E-15 T 09-11-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PRINTS PR00758 Arsenical pump membrane protein signature 315 337 4.3E-15 T 09-11-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PRINTS PR00758 Arsenical pump membrane protein signature 97 121 4.3E-15 T 09-11-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PRINTS PR00758 Arsenical pump membrane protein signature 357 382 4.3E-15 T 09-11-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PRINTS PR00758 Arsenical pump membrane protein signature 390 414 4.3E-15 T 09-11-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PRINTS PR00758 Arsenical pump membrane protein signature 213 238 4.3E-15 T 09-11-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 Pfam PF03600 Citrate transporter 13 361 4.7E-52 T 09-11-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 CLOSPO_RS15835 51f42dc513665b1a8620f32242f1c9cd 420 PANTHER PTHR10283 1 418 7.1E-162 T 09-11-2016 CLOSPO_RS15030 27a80a6bffd2e26ceb7f907c202c5801 261 SUPERFAMILY SSF56281 2 251 6.98E-45 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15030 27a80a6bffd2e26ceb7f907c202c5801 261 PANTHER PTHR13754 1 257 7.6E-100 T 09-11-2016 CLOSPO_RS15030 27a80a6bffd2e26ceb7f907c202c5801 261 Pfam PF12706 Beta-lactamase superfamily domain 23 201 3.4E-23 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15030 27a80a6bffd2e26ceb7f907c202c5801 261 SMART SM00849 11 190 7.4E-14 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15030 27a80a6bffd2e26ceb7f907c202c5801 261 Gene3D G3DSA:3.60.15.10 13 243 2.7E-36 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS15030 27a80a6bffd2e26ceb7f907c202c5801 261 PANTHER PTHR13754:SF15 1 257 7.6E-100 T 09-11-2016 CLOSPO_RS18820 f9a205ca28bc64ae11b193e461abcb48 331 PANTHER PTHR40064 2 328 5.7E-138 T 09-11-2016 CLOSPO_RS18820 f9a205ca28bc64ae11b193e461abcb48 331 Pfam PF06081 Aromatic acid exporter family member 1 3 142 1.2E-48 T 09-11-2016 IPR010343 Aromatic acid exporter family member 1 CLOSPO_RS18820 f9a205ca28bc64ae11b193e461abcb48 331 PANTHER PTHR40064:SF1 2 328 5.7E-138 T 09-11-2016 CLOSPO_RS18820 f9a205ca28bc64ae11b193e461abcb48 331 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 311 6.4E-54 T 09-11-2016 IPR021062 Putative aromatic acid exporter, C-terminal CLOSPO_RS14100 c4b88cf3cca785d471489b9dfe5d1ad1 392 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 228 389 5.9E-32 T 09-11-2016 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CLOSPO_RS14100 c4b88cf3cca785d471489b9dfe5d1ad1 392 PANTHER PTHR35789 65 392 1.7E-117 T 09-11-2016 CLOSPO_RS14100 c4b88cf3cca785d471489b9dfe5d1ad1 392 PANTHER PTHR35789 1 47 1.7E-117 T 09-11-2016 CLOSPO_RS14100 c4b88cf3cca785d471489b9dfe5d1ad1 392 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 392 4.5E-106 T 09-11-2016 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CLOSPO_RS14100 c4b88cf3cca785d471489b9dfe5d1ad1 392 PANTHER PTHR35789:SF1 1 47 1.7E-117 T 09-11-2016 CLOSPO_RS14100 c4b88cf3cca785d471489b9dfe5d1ad1 392 PANTHER PTHR35789:SF1 65 392 1.7E-117 T 09-11-2016 CLOSPO_RS17705 fcbb33058607b2d7b40f02a449292671 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 80 2.5E-4 T 09-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 CLOSPO_RS17705 fcbb33058607b2d7b40f02a449292671 140 Gene3D G3DSA:2.30.110.10 1 140 1.3E-57 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS17705 fcbb33058607b2d7b40f02a449292671 140 SUPERFAMILY SSF50475 6 112 4.12E-10 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 PANTHER PTHR11649:SF37 1 141 7.0E-254 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 SUPERFAMILY SSF52540 1 157 1.48E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 PANTHER PTHR11649 190 586 7.0E-254 T 09-11-2016 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 Pfam PF02421 Ferrous iron transport protein B 3 153 2.0E-60 T 09-11-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 Pfam PF07664 Ferrous iron transport protein B C terminus 382 434 2.5E-21 T 09-11-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 Gene3D G3DSA:3.40.50.300 2 158 1.5E-34 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 PANTHER PTHR11649:SF37 190 586 7.0E-254 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 193 555 2.3E-123 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 Pfam PF07670 Nucleoside recognition 278 369 6.5E-15 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 Pfam PF07670 Nucleoside recognition 439 559 9.3E-34 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS18905 8fcf8a6b7e22d3fed9db12f4349e2954 587 PANTHER PTHR11649 1 141 7.0E-254 T 09-11-2016 CLOSPO_RS16890 5b3b8ddfb4c6b18e09f2d5b891d0a776 422 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 32 413 7.2E-62 T 09-11-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 CLOSPO_RS16890 5b3b8ddfb4c6b18e09f2d5b891d0a776 422 SUPERFAMILY SSF53807 15 412 2.68E-59 T 09-11-2016 CLOSPO_RS16890 5b3b8ddfb4c6b18e09f2d5b891d0a776 422 PANTHER PTHR33712:SF2 1 422 1.4E-163 T 09-11-2016 CLOSPO_RS16890 5b3b8ddfb4c6b18e09f2d5b891d0a776 422 Gene3D G3DSA:3.40.50.1980 32 162 5.2E-22 T 09-11-2016 CLOSPO_RS16890 5b3b8ddfb4c6b18e09f2d5b891d0a776 422 Gene3D G3DSA:3.40.50.1980 167 271 1.6E-6 T 09-11-2016 CLOSPO_RS16890 5b3b8ddfb4c6b18e09f2d5b891d0a776 422 PANTHER PTHR33712 1 422 1.4E-163 T 09-11-2016 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 SUPERFAMILY SSF46689 7 76 1.97E-16 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 Gene3D G3DSA:3.40.50.10490 86 253 2.0E-20 T 09-11-2016 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 PANTHER PTHR30514 8 258 7.9E-73 T 09-11-2016 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 PANTHER PTHR30514:SF1 8 258 7.9E-73 T 09-11-2016 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 SUPERFAMILY SSF53697 87 252 2.45E-24 T 09-11-2016 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 75 1.4E-15 T 09-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 Gene3D G3DSA:1.10.10.10 8 76 1.1E-19 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13280 943f3647e32dc0995ba6060f2d0cd6a5 259 Pfam PF01380 SIS domain 117 223 6.8E-12 T 09-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 CLOSPO_RS16090 a2febb3a391db108b2d98660e4a21ffc 547 PANTHER PTHR30252:SF0 1 546 3.9E-232 T 09-11-2016 CLOSPO_RS16090 a2febb3a391db108b2d98660e4a21ffc 547 PANTHER PTHR30252 1 546 3.9E-232 T 09-11-2016 CLOSPO_RS16090 a2febb3a391db108b2d98660e4a21ffc 547 Pfam PF02554 Carbon starvation protein CstA 1 351 2.7E-126 T 09-11-2016 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CLOSPO_RS16090 a2febb3a391db108b2d98660e4a21ffc 547 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 376 495 1.5E-38 T 09-11-2016 IPR025299 CstA, C-terminal domain CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 9 281 8.2E-83 T 09-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 Gene3D G3DSA:3.40.1010.10 7 116 1.9E-18 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 207 5.4E-32 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 8 226 37.144 T 09-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 SUPERFAMILY SSF53790 7 224 9.68E-81 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 PANTHER PTHR21091:SF18 1 249 1.5E-92 T 09-11-2016 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 Gene3D G3DSA:3.30.950.10 117 227 9.8E-41 T 09-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 86 97 - T 09-11-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 PANTHER PTHR21091 1 249 1.5E-92 T 09-11-2016 CLOSPO_RS14420 f987f4362d7f5a1b60b0208e2d122314 284 PIRSF PIRSF005917 1 284 1.0E-103 T 09-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CLOSPO_RS18160 fd61d1c55c0f91c30b0fea12147bb249 255 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 250 1.3E-66 T 09-11-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CLOSPO_RS18160 fd61d1c55c0f91c30b0fea12147bb249 255 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 252 7.5E-58 T 09-11-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CLOSPO_RS18160 fd61d1c55c0f91c30b0fea12147bb249 255 PANTHER PTHR36925 1 255 2.1E-86 T 09-11-2016 CLOSPO_RS13815 773198ff25b55e40c1c9b4758e010727 86 Pfam PF01312 FlhB HrpN YscU SpaS Family 2 78 8.0E-19 T 09-11-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOSPO_RS13815 773198ff25b55e40c1c9b4758e010727 86 PANTHER PTHR30531 1 86 2.5E-63 T 09-11-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOSPO_RS13815 773198ff25b55e40c1c9b4758e010727 86 Gene3D G3DSA:3.40.1690.10 5 82 2.1E-22 T 09-11-2016 IPR029025 Type III secretion system substrate exporter, C-terminal CLOSPO_RS13815 773198ff25b55e40c1c9b4758e010727 86 SUPERFAMILY SSF160544 2 82 1.44E-21 T 09-11-2016 IPR029025 Type III secretion system substrate exporter, C-terminal CLOSPO_RS13815 773198ff25b55e40c1c9b4758e010727 86 PANTHER PTHR30531:SF5 1 86 2.5E-63 T 09-11-2016 CLOSPO_RS10820 01e67b577cde72b728387ead49e3467e 57 SUPERFAMILY SSF141986 3 57 4.32E-6 T 09-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain CLOSPO_RS10820 01e67b577cde72b728387ead49e3467e 57 Pfam PF02016 LD-carboxypeptidase 3 57 1.8E-6 T 09-11-2016 IPR003507 Peptidase family S66 CLOSPO_RS10820 01e67b577cde72b728387ead49e3467e 57 PANTHER PTHR30237 1 57 5.8E-24 T 09-11-2016 CLOSPO_RS10820 01e67b577cde72b728387ead49e3467e 57 Gene3D G3DSA:3.50.30.60 3 57 9.8E-7 T 09-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain CLOSPO_RS10820 01e67b577cde72b728387ead49e3467e 57 PANTHER PTHR30237:SF4 1 57 5.8E-24 T 09-11-2016 CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 67 238 2.8E-13 T 09-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 352 3.7E-34 T 09-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 Gene3D G3DSA:2.40.50.100 151 191 2.6E-9 T 09-11-2016 CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 Gene3D G3DSA:2.40.50.100 67 89 2.6E-9 T 09-11-2016 CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 PANTHER PTHR32347:SF14 1 352 1.2E-64 T 09-11-2016 CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 PANTHER PTHR32347 1 352 1.2E-64 T 09-11-2016 CLOSPO_RS14305 9c144f94b09850a4cfb40092d68f80ca 353 SUPERFAMILY SSF111369 68 232 9.55E-9 T 09-11-2016 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 Pfam PF03466 LysR substrate binding domain 87 291 4.4E-33 T 09-11-2016 IPR005119 LysR, substrate-binding CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-5 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-5 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-5 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.3E-16 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 Gene3D G3DSA:1.10.10.10 1 79 5.4E-23 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 Gene3D G3DSA:3.40.190.10 198 262 1.1E-10 T 09-11-2016 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 SUPERFAMILY SSF46785 1 84 2.91E-20 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 Gene3D G3DSA:3.40.190.10 82 197 4.7E-16 T 09-11-2016 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 PANTHER PTHR30126 1 297 1.2E-124 T 09-11-2016 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 PANTHER PTHR30126:SF31 1 297 1.2E-124 T 09-11-2016 CLOSPO_RS18575 2379bd8248fccf308e2a424e95f6e1ce 297 SUPERFAMILY SSF53850 88 294 5.43E-29 T 09-11-2016 CLOSPO_RS14355 60d951186764b1a79dee4b605c28bcd1 144 SUPERFAMILY SSF46785 16 140 2.03E-21 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14355 60d951186764b1a79dee4b605c28bcd1 144 PANTHER PTHR33164:SF17 3 143 6.0E-48 T 09-11-2016 CLOSPO_RS14355 60d951186764b1a79dee4b605c28bcd1 144 SMART SM00347 26 126 1.6E-13 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14355 60d951186764b1a79dee4b605c28bcd1 144 Pfam PF01047 MarR family 33 90 1.1E-11 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS14355 60d951186764b1a79dee4b605c28bcd1 144 Gene3D G3DSA:1.10.10.10 3 138 5.8E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS14355 60d951186764b1a79dee4b605c28bcd1 144 PANTHER PTHR33164 3 143 6.0E-48 T 09-11-2016 CLOSPO_RS18350 f3b41f28477ebd289bc4fffd61a909dc 204 Pfam PF11193 Protein of unknown function (DUF2812) 9 118 2.1E-30 T 09-11-2016 IPR021359 Protein of unknown function DUF2812 CLOSPO_RS18350 f3b41f28477ebd289bc4fffd61a909dc 204 PANTHER PTHR41258 1 202 7.0E-64 T 09-11-2016 CLOSPO_RS16525 174c607352a2aead605fa2fe31ae1f4d 292 Gene3D G3DSA:1.25.40.10 90 194 1.5E-4 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16525 174c607352a2aead605fa2fe31ae1f4d 292 Gene3D G3DSA:1.25.40.10 38 74 2.1E-4 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16525 174c607352a2aead605fa2fe31ae1f4d 292 SUPERFAMILY SSF48452 38 184 7.41E-10 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS13510 2d0e8194e5811fb1148726f7656f7da0 160 Pfam PF05154 TM2 domain 85 143 8.4E-13 T 09-11-2016 IPR007829 TM2 domain CLOSPO_RS13510 2d0e8194e5811fb1148726f7656f7da0 160 Pfam PF12773 Double zinc ribbon 25 62 1.3E-6 T 09-11-2016 IPR025874 Double zinc ribbon CLOSPO_RS14800 6b222d07c6e42331115601afc1cbd101 325 SMART SM00382 182 305 0.0025 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS14800 6b222d07c6e42331115601afc1cbd101 325 PANTHER PTHR30050 29 325 9.7E-111 T 09-11-2016 CLOSPO_RS14800 6b222d07c6e42331115601afc1cbd101 325 Gene3D G3DSA:3.40.50.300 119 310 1.4E-30 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14800 6b222d07c6e42331115601afc1cbd101 325 Pfam PF01695 IstB-like ATP binding protein 156 289 3.1E-19 T 09-11-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 CLOSPO_RS14800 6b222d07c6e42331115601afc1cbd101 325 SUPERFAMILY SSF52540 153 309 1.73E-22 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14800 6b222d07c6e42331115601afc1cbd101 325 PANTHER PTHR30050:SF7 29 325 9.7E-111 T 09-11-2016 CLOSPO_RS14955 044469f7734a2191012df15583831198 428 TIGRFAM TIGR04481 PR_assoc_PrdC: proline reductase-associated electron transfer protein PrdC 5 428 3.5E-212 T 09-11-2016 IPR031001 Proline reductase-associated electron transfer protein PrdC CLOSPO_RS14955 044469f7734a2191012df15583831198 428 Gene3D G3DSA:2.40.50.100 12 54 2.2E-4 T 09-11-2016 CLOSPO_RS14955 044469f7734a2191012df15583831198 428 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 84 226 2.9E-37 T 09-11-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain CLOSPO_RS14955 044469f7734a2191012df15583831198 428 Pfam PF13375 RnfC Barrel sandwich hybrid domain 4 59 4.0E-14 T 09-11-2016 IPR026902 RnfC Barrel sandwich hybrid domain CLOSPO_RS14955 044469f7734a2191012df15583831198 428 SUPERFAMILY SSF142019 42 244 5.75E-46 T 09-11-2016 CLOSPO_RS14955 044469f7734a2191012df15583831198 428 PANTHER PTHR11780 5 307 2.3E-82 T 09-11-2016 CLOSPO_RS14955 044469f7734a2191012df15583831198 428 SUPERFAMILY SSF142984 240 307 9.55E-7 T 09-11-2016 CLOSPO_RS14955 044469f7734a2191012df15583831198 428 PANTHER PTHR11780:SF1 5 307 2.3E-82 T 09-11-2016 CLOSPO_RS10080 9380a7b1d41d5638166c6b3a727841c3 139 Pfam PF01595 Domain of unknown function DUF21 8 137 2.4E-28 T 09-11-2016 IPR002550 Domain of unknown function DUF21 CLOSPO_RS10080 9380a7b1d41d5638166c6b3a727841c3 139 PANTHER PTHR22777:SF8 1 139 3.5E-51 T 09-11-2016 CLOSPO_RS10080 9380a7b1d41d5638166c6b3a727841c3 139 PANTHER PTHR22777 1 139 3.5E-51 T 09-11-2016 CLOSPO_RS13550 d743721793d4505d320ee815e8f8eac5 77 Pfam PF03840 Preprotein translocase SecG subunit 6 74 9.2E-20 T 09-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOSPO_RS13550 d743721793d4505d320ee815e8f8eac5 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 6.9E-22 T 09-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOSPO_RS13550 d743721793d4505d320ee815e8f8eac5 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.8E-5 T 09-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOSPO_RS13550 d743721793d4505d320ee815e8f8eac5 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 3.8E-5 T 09-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOSPO_RS13550 d743721793d4505d320ee815e8f8eac5 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.8E-5 T 09-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOSPO_RS15020 d4215d2be2e0aa950a6448a8390f6d5e 167 PANTHER PTHR33747 1 165 5.5E-39 T 09-11-2016 CLOSPO_RS15020 d4215d2be2e0aa950a6448a8390f6d5e 167 PANTHER PTHR33747:SF1 1 165 5.5E-39 T 09-11-2016 CLOSPO_RS15020 d4215d2be2e0aa950a6448a8390f6d5e 167 SUPERFAMILY SSF103642 144 165 4.25E-8 T 09-11-2016 CLOSPO_RS15020 d4215d2be2e0aa950a6448a8390f6d5e 167 Pfam PF02810 SEC-C motif 147 165 2.3E-10 T 09-11-2016 IPR004027 SEC-C motif CLOSPO_RS15020 d4215d2be2e0aa950a6448a8390f6d5e 167 Gene3D G3DSA:3.10.450.50 124 165 7.9E-14 T 09-11-2016 IPR032710 NTF2-like domain CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 288 4.4E-14 T 09-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 PANTHER PTHR24220:SF586 6 313 7.1E-105 T 09-11-2016 CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 SUPERFAMILY SSF52540 4 255 1.33E-51 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 308 9.2E-20 T 09-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 PANTHER PTHR24220 6 313 7.1E-105 T 09-11-2016 CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 Gene3D G3DSA:3.40.50.300 5 250 2.8E-59 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 Pfam PF00005 ABC transporter 24 177 1.5E-20 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16650 3aaaec14f5262f7392e281d6f906da06 313 SMART SM00382 33 236 1.1E-5 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17870 d4bdee4762f0e28aeb2d44100fdd8ef1 285 SUPERFAMILY SSF89260 28 156 5.36E-5 T 09-11-2016 CLOSPO_RS17870 d4bdee4762f0e28aeb2d44100fdd8ef1 285 Gene3D G3DSA:2.60.120.380 27 156 8.7E-12 T 09-11-2016 CLOSPO_RS18705 c79ab02ea32a9540f469131a92c9c83e 314 PANTHER PTHR30532:SF4 1 313 8.2E-147 T 09-11-2016 CLOSPO_RS18705 c79ab02ea32a9540f469131a92c9c83e 314 SUPERFAMILY SSF53807 38 306 1.57E-65 T 09-11-2016 CLOSPO_RS18705 c79ab02ea32a9540f469131a92c9c83e 314 Gene3D G3DSA:3.40.50.1980 162 313 2.6E-34 T 09-11-2016 CLOSPO_RS18705 c79ab02ea32a9540f469131a92c9c83e 314 PANTHER PTHR30532 1 313 8.2E-147 T 09-11-2016 CLOSPO_RS18705 c79ab02ea32a9540f469131a92c9c83e 314 Gene3D G3DSA:3.40.50.1980 38 161 2.9E-32 T 09-11-2016 CLOSPO_RS18705 c79ab02ea32a9540f469131a92c9c83e 314 Pfam PF01497 Periplasmic binding protein 56 290 4.7E-34 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS06355 fdd67a1e424060f39eb388bb7ade4406 90 PANTHER PTHR24220:SF123 8 89 1.3E-17 T 09-11-2016 CLOSPO_RS06355 fdd67a1e424060f39eb388bb7ade4406 90 PANTHER PTHR24220 8 89 1.3E-17 T 09-11-2016 CLOSPO_RS06355 fdd67a1e424060f39eb388bb7ade4406 90 SUPERFAMILY SSF52540 8 85 6.08E-17 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS06355 fdd67a1e424060f39eb388bb7ade4406 90 Pfam PF00005 ABC transporter 8 82 1.2E-15 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS06355 fdd67a1e424060f39eb388bb7ade4406 90 Gene3D G3DSA:3.40.50.300 7 86 9.5E-19 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PANTHER PTHR10836:SF37 1 334 7.2E-219 T 09-11-2016 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 Gene3D G3DSA:3.40.50.720 1 161 2.8E-78 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 SMART SM00846 2 153 2.4E-95 T 09-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 153 1.3E-60 T 09-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 326 2.9E-141 T 09-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 3.8E-72 T 09-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PIRSF PIRSF000149 1 335 9.9E-141 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 Gene3D G3DSA:3.30.360.10 162 316 8.3E-81 T 09-11-2016 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PANTHER PTHR10836 1 334 7.2E-219 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 09-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 SUPERFAMILY SSF51735 2 169 1.39E-66 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 SUPERFAMILY SSF55347 153 315 1.73E-75 T 09-11-2016 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.3E-40 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.3E-40 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.3E-40 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.3E-40 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS13575 b780694e970a6b1208edd7353eab7c72 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.3E-40 T 09-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 CLOSPO_RS14670 fb613c4bb4c1056d2f07e4da77bbdf19 105 Pfam PF12643 MazG-like family 8 94 9.9E-26 T 09-11-2016 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12 CLOSPO_RS17720 394364b2ebc9a49315a87087cfa3ba16 253 PANTHER PTHR31082 3 253 1.4E-75 T 09-11-2016 CLOSPO_RS17720 394364b2ebc9a49315a87087cfa3ba16 253 Pfam PF06738 Putative threonine/serine exporter 11 248 1.5E-61 T 09-11-2016 IPR010619 Putative threonine/serine exporter CLOSPO_RS17720 394364b2ebc9a49315a87087cfa3ba16 253 PANTHER PTHR31082:SF6 3 253 1.4E-75 T 09-11-2016 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 SMART SM00052 640 885 1.1E-103 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 SUPERFAMILY SSF55073 477 631 1.1E-43 T 09-11-2016 IPR029787 Nucleotide cyclase CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 471 629 1.0E-39 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 PANTHER PTHR10799 503 719 5.5E-71 T 09-11-2016 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 PANTHER PTHR10799 852 871 5.5E-71 T 09-11-2016 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 Pfam PF00563 EAL domain 646 880 1.2E-74 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 Pfam PF00672 HAMP domain 263 332 2.1E-8 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 Pfam PF00990 Diguanylate cyclase, GGDEF domain 472 624 8.7E-43 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 SUPERFAMILY SSF141868 645 889 6.93E-87 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 PANTHER PTHR10799:SF774 503 719 5.5E-71 T 09-11-2016 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 PANTHER PTHR10799:SF774 852 871 5.5E-71 T 09-11-2016 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 Gene3D G3DSA:3.20.20.450 644 888 5.2E-94 T 09-11-2016 IPR001633 EAL domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 SMART SM00267 461 630 2.9E-51 T 09-11-2016 IPR000160 GGDEF domain CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 Pfam PF05228 CHASE4 domain 53 198 9.3E-27 T 09-11-2016 IPR007892 CHASE4 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 SMART SM00304 283 336 1.7E-5 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS12880 a7f776f4a0e2b1f53cf8b47ac95069d9 892 Gene3D G3DSA:3.30.70.270 473 638 1.7E-50 T 09-11-2016 CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 Gene3D G3DSA:3.40.50.300 162 218 8.8E-7 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 Gene3D G3DSA:3.40.50.300 42 107 2.9E-7 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 7 217 2.0E-74 T 09-11-2016 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 PANTHER PTHR30134 1 221 2.2E-108 T 09-11-2016 CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 PIRSF PIRSF005624 2 222 1.2E-80 T 09-11-2016 CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 PANTHER PTHR30134:SF2 1 221 2.2E-108 T 09-11-2016 CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 SUPERFAMILY SSF52540 5 219 1.51E-40 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17370 3a7225799e82b4ab0110301927d13865 222 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 36 196 3.5E-25 T 09-11-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 279 1.6E-87 T 09-11-2016 IPR003797 DegV CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 PANTHER PTHR33434:SF3 1 283 2.6E-108 T 09-11-2016 CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 Gene3D G3DSA:3.40.50.10170 3 150 2.8E-39 T 09-11-2016 CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 SUPERFAMILY SSF82549 2 280 2.88E-77 T 09-11-2016 CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 PANTHER PTHR33434 1 283 2.6E-108 T 09-11-2016 CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 Gene3D G3DSA:3.30.1180.10 152 282 5.0E-39 T 09-11-2016 CLOSPO_RS16305 888e34f513a0aaa281ba31a75a15fbbe 288 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 280 1.1E-84 T 09-11-2016 IPR003797 DegV CLOSPO_RS15610 c9288b7c7a490a656745936316509b52 290 PANTHER PTHR11795:SF371 1 290 5.2E-118 T 09-11-2016 CLOSPO_RS15610 c9288b7c7a490a656745936316509b52 290 PANTHER PTHR11795 1 290 5.2E-118 T 09-11-2016 CLOSPO_RS15610 c9288b7c7a490a656745936316509b52 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 274 3.5E-44 T 09-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 6.2E-26 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 PANTHER PTHR26402 3 227 4.4E-97 T 09-11-2016 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 Pfam PF00072 Response regulator receiver domain 5 113 1.9E-30 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 PANTHER PTHR26402:SF50 3 227 4.4E-97 T 09-11-2016 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 SMART SM00862 151 227 6.9E-25 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 Gene3D G3DSA:1.10.10.10 129 227 6.9E-34 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 SMART SM00448 3 113 1.2E-42 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 SUPERFAMILY SSF52172 2 130 4.41E-41 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 SUPERFAMILY SSF46894 127 227 1.02E-29 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS13380 749a9d3f531fe9267fac3d68b21b989f 227 Gene3D G3DSA:3.40.50.2300 2 124 1.2E-39 T 09-11-2016 CLOSPO_RS13665 90d37159e7de1f41c1b37674adcf9baa 233 PANTHER PTHR10434 1 232 2.5E-52 T 09-11-2016 CLOSPO_RS13665 90d37159e7de1f41c1b37674adcf9baa 233 Gene3D G3DSA:3.40.1130.10 33 222 8.1E-30 T 09-11-2016 CLOSPO_RS13665 90d37159e7de1f41c1b37674adcf9baa 233 SMART SM00563 51 164 2.3E-25 T 09-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CLOSPO_RS13665 90d37159e7de1f41c1b37674adcf9baa 233 SUPERFAMILY SSF69593 20 232 4.18E-46 T 09-11-2016 CLOSPO_RS13665 90d37159e7de1f41c1b37674adcf9baa 233 Pfam PF01553 Acyltransferase 36 162 1.9E-22 T 09-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CLOSPO_RS13665 90d37159e7de1f41c1b37674adcf9baa 233 PANTHER PTHR10434:SF21 1 232 2.5E-52 T 09-11-2016 CLOSPO_RS18640 7a333cf99fadc3881ba55ad95ea60974 240 PANTHER PTHR34582 1 236 1.7E-42 T 09-11-2016 CLOSPO_RS18640 7a333cf99fadc3881ba55ad95ea60974 240 Gene3D G3DSA:3.30.240.20 180 235 7.1E-18 T 09-11-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CLOSPO_RS18640 7a333cf99fadc3881ba55ad95ea60974 240 PANTHER PTHR34582:SF4 1 236 1.7E-42 T 09-11-2016 CLOSPO_RS18640 7a333cf99fadc3881ba55ad95ea60974 240 Gene3D G3DSA:3.30.240.20 92 167 4.2E-18 T 09-11-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CLOSPO_RS18640 7a333cf99fadc3881ba55ad95ea60974 240 Pfam PF04239 Protein of unknown function (DUF421) 180 234 5.6E-8 T 09-11-2016 IPR007353 Protein of unknown function DUF421 CLOSPO_RS18640 7a333cf99fadc3881ba55ad95ea60974 240 Pfam PF04239 Protein of unknown function (DUF421) 101 215 3.9E-25 T 09-11-2016 IPR007353 Protein of unknown function DUF421 CLOSPO_RS17445 451751a266cea8ce9a74034af0b36d53 164 Gene3D G3DSA:3.40.630.30 2 157 6.8E-26 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17445 451751a266cea8ce9a74034af0b36d53 164 PANTHER PTHR13256 1 160 9.9E-51 T 09-11-2016 CLOSPO_RS17445 451751a266cea8ce9a74034af0b36d53 164 Pfam PF13302 Acetyltransferase (GNAT) domain 65 152 1.8E-18 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS17445 451751a266cea8ce9a74034af0b36d53 164 PANTHER PTHR13256:SF42 1 160 9.9E-51 T 09-11-2016 CLOSPO_RS17445 451751a266cea8ce9a74034af0b36d53 164 SUPERFAMILY SSF55729 2 155 2.76E-24 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 1.8E-14 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PRINTS PR00723 Subtilisin serine protease family (S8) signature 203 216 1.8E-14 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PRINTS PR00723 Subtilisin serine protease family (S8) signature 408 424 1.8E-14 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 Gene3D G3DSA:3.30.70.80 44 92 2.9E-4 T 09-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 409 419 - T 09-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PANTHER PTHR10795 345 467 1.9E-45 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PANTHER PTHR10795:SF368 135 320 1.9E-45 T 09-11-2016 CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PANTHER PTHR10795:SF368 6 114 1.9E-45 T 09-11-2016 CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PANTHER PTHR10795:SF368 345 467 1.9E-45 T 09-11-2016 CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 Pfam PF00082 Subtilase family 155 459 1.0E-47 T 09-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PANTHER PTHR10795 6 114 1.9E-45 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 PANTHER PTHR10795 135 320 1.9E-45 T 09-11-2016 IPR015500 Peptidase S8, subtilisin-related CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 207 217 - T 09-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 SUPERFAMILY SSF54897 43 101 4.82E-6 T 09-11-2016 IPR009020 Proteinase inhibitor, propeptide CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 159 170 - T 09-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 SUPERFAMILY SSF52743 145 467 4.32E-62 T 09-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CLOSPO_RS16560 3b3105a621708407199ed2b48e0c2d26 469 Gene3D G3DSA:3.40.50.200 93 467 4.9E-69 T 09-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 TIGRFAM TIGR04334 rSAM_Clo7bot: radical SAM/SPASM domain Clo7bot peptide maturase 2 440 5.9E-258 T 09-11-2016 IPR027622 Radical SAM/SPASM domain-containing Clo7bot peptide maturase CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 333 415 1.7E-14 T 09-11-2016 IPR023885 4Fe4S-binding SPASM domain CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 PANTHER PTHR11228:SF5 36 429 5.7E-124 T 09-11-2016 CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 Pfam PF13353 4Fe-4S single cluster domain 100 217 1.1E-11 T 09-11-2016 CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 Pfam PF04055 Radical SAM superfamily 97 262 2.0E-21 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 SUPERFAMILY SSF102114 93 407 3.79E-45 T 09-11-2016 CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 Gene3D G3DSA:3.20.20.70 93 410 7.0E-45 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS16240 849d56990e7fd6709f072d2227522256 450 PANTHER PTHR11228 36 429 5.7E-124 T 09-11-2016 CLOSPO_RS03305 ded258683845a59e315ea9f5570b8afc 55 SUPERFAMILY SSF54593 5 54 6.86E-9 T 09-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOSPO_RS03305 ded258683845a59e315ea9f5570b8afc 55 Pfam PF12681 Glyoxalase-like domain 2 55 3.6E-23 T 09-11-2016 IPR025870 Glyoxalase-like domain CLOSPO_RS03305 ded258683845a59e315ea9f5570b8afc 55 Gene3D G3DSA:3.10.180.10 5 54 1.5E-11 T 09-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOSPO_RS18310 0ffcef41102ab6bb3d02331a35391531 154 Pfam PF13673 Acetyltransferase (GNAT) domain 28 143 3.2E-20 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18310 0ffcef41102ab6bb3d02331a35391531 154 SUPERFAMILY SSF55729 1 153 7.38E-35 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18310 0ffcef41102ab6bb3d02331a35391531 154 Gene3D G3DSA:3.40.630.30 1 153 3.3E-42 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18310 0ffcef41102ab6bb3d02331a35391531 154 PANTHER PTHR23091 1 134 5.7E-17 T 09-11-2016 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 SUPERFAMILY SSF52540 5 555 3.78E-250 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 Gene3D G3DSA:3.30.1510.10 130 248 4.2E-54 T 09-11-2016 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 2 557 49.17 T 09-11-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 09-11-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 09-11-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 Pfam PF01268 Formate--tetrahydrofolate ligase 3 557 2.6E-275 T 09-11-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 Gene3D G3DSA:3.40.50.300 14 129 8.4E-153 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 Gene3D G3DSA:3.40.50.300 249 441 8.4E-153 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 PANTHER PTHR10025 2 556 0.0 T 09-11-2016 CLOSPO_RS15280 348507c4d8448b1fd86171eebbf61038 557 Gene3D G3DSA:3.10.410.10 445 533 4.7E-40 T 09-11-2016 CLOSPO_RS17000 4742b2ace373c4ba0f540c6d20bcc147 185 Pfam PF14568 SMI1-KNR4 cell-wall 28 162 1.4E-27 T 09-11-2016 CLOSPO_RS17000 4742b2ace373c4ba0f540c6d20bcc147 185 SUPERFAMILY SSF160631 16 168 8.37E-29 T 09-11-2016 CLOSPO_RS17000 4742b2ace373c4ba0f540c6d20bcc147 185 Gene3D G3DSA:3.40.1580.10 2 169 3.1E-30 T 09-11-2016 IPR018958 SMI1/KNR4-like domain CLOSPO_RS17000 4742b2ace373c4ba0f540c6d20bcc147 185 SMART SM00860 26 164 2.3E-8 T 09-11-2016 IPR018958 SMI1/KNR4-like domain CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 Gene3D G3DSA:1.10.10.10 132 223 1.4E-27 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 PANTHER PTHR26402:SF581 3 223 1.1E-150 T 09-11-2016 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 Pfam PF00072 Response regulator receiver domain 5 111 3.2E-25 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 SMART SM00862 150 221 3.4E-21 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 Gene3D G3DSA:3.40.50.2300 2 120 8.8E-38 T 09-11-2016 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 SUPERFAMILY SSF46894 131 222 1.22E-24 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 221 3.1E-22 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 SUPERFAMILY SSF52172 2 126 1.57E-33 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 SMART SM00448 3 113 1.5E-36 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS13150 2c662e95162dac80edfd42806bd8feb3 224 PANTHER PTHR26402 3 223 1.1E-150 T 09-11-2016 CLOSPO_RS14900 31d7cb771d98bfcf0cc14d76d531e990 143 PANTHER PTHR34821:SF3 1 140 1.2E-71 T 09-11-2016 CLOSPO_RS14900 31d7cb771d98bfcf0cc14d76d531e990 143 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 138 9.9E-31 T 09-11-2016 IPR006750 Putative inner membrane exporter, YdcZ CLOSPO_RS14900 31d7cb771d98bfcf0cc14d76d531e990 143 PANTHER PTHR34821 1 140 1.2E-71 T 09-11-2016 CLOSPO_RS12125 4edca8651b0861864d55cd4bde2ec811 183 Gene3D G3DSA:3.20.20.70 58 179 3.6E-10 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS12125 4edca8651b0861864d55cd4bde2ec811 183 PANTHER PTHR30544:SF5 2 183 1.7E-84 T 09-11-2016 CLOSPO_RS12125 4edca8651b0861864d55cd4bde2ec811 183 Pfam PF13394 4Fe-4S single cluster domain 72 161 3.8E-8 T 09-11-2016 CLOSPO_RS12125 4edca8651b0861864d55cd4bde2ec811 183 SUPERFAMILY SSF102114 61 181 3.53E-8 T 09-11-2016 CLOSPO_RS12125 4edca8651b0861864d55cd4bde2ec811 183 PANTHER PTHR30544 2 183 1.7E-84 T 09-11-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CLOSPO_RS12125 4edca8651b0861864d55cd4bde2ec811 183 Pfam PF04055 Radical SAM superfamily 67 181 1.6E-11 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 8 159 1.1E-57 T 09-11-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 Pfam PF00588 SpoU rRNA Methylase family 8 148 5.5E-33 T 09-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 PANTHER PTHR12029 8 159 4.1E-74 T 09-11-2016 CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 SUPERFAMILY SSF75217 8 159 8.5E-43 T 09-11-2016 IPR029028 Alpha/beta knot methyltransferases CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 PANTHER PTHR12029:SF31 8 159 4.1E-74 T 09-11-2016 CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 PIRSF PIRSF029256 7 160 9.1E-66 T 09-11-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 Gene3D G3DSA:3.40.1280.10 7 159 1.6E-63 T 09-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOSPO_RS13620 5877ee448fa83b83699ef992d15a54d1 160 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 8 157 35.588 T 09-11-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CLOSPO_RS13395 71d33d956dc99a21cfd9ed8ee152d52c 488 Pfam PF07731 Multicopper oxidase 52 182 5.4E-9 T 09-11-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CLOSPO_RS13395 71d33d956dc99a21cfd9ed8ee152d52c 488 SUPERFAMILY SSF49503 73 182 2.01E-21 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS13395 71d33d956dc99a21cfd9ed8ee152d52c 488 Gene3D G3DSA:2.60.40.420 455 470 2.1E-16 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS13395 71d33d956dc99a21cfd9ed8ee152d52c 488 Gene3D G3DSA:2.60.40.420 241 387 2.1E-16 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS13395 71d33d956dc99a21cfd9ed8ee152d52c 488 Gene3D G3DSA:2.60.40.420 68 180 7.9E-19 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS13395 71d33d956dc99a21cfd9ed8ee152d52c 488 SUPERFAMILY SSF49503 228 385 1.38E-13 T 09-11-2016 IPR008972 Cupredoxin CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 SUPERFAMILY SSF51306 117 214 6.45E-10 T 09-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 Gene3D G3DSA:1.10.260.40 4 63 3.0E-16 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 Gene3D G3DSA:2.10.109.10 127 215 1.1E-4 T 09-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 PANTHER PTHR10245 3 210 2.2E-44 T 09-11-2016 CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 PANTHER PTHR10245:SF43 3 210 2.2E-44 T 09-11-2016 CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 SUPERFAMILY SSF47413 4 62 1.39E-14 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 SMART SM00530 7 62 5.0E-14 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS15065 16aee7bd1bccb23e40032c3ee5ec4b83 220 Pfam PF01381 Helix-turn-helix 8 60 3.2E-13 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 PANTHER PTHR18964:SF2 2 384 9.5E-215 T 09-11-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 PANTHER PTHR18964 2 384 9.5E-215 T 09-11-2016 CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 367 3.4E-122 T 09-11-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 Gene3D G3DSA:3.40.50.2000 3 205 7.4E-87 T 09-11-2016 CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 Gene3D G3DSA:3.40.50.2000 206 370 3.4E-64 T 09-11-2016 CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 SUPERFAMILY SSF53756 3 374 4.76E-135 T 09-11-2016 CLOSPO_RS13985 fa3e384ec9fa319f89739252022ce3c7 385 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 370 1.2E-159 T 09-11-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 CLOSPO_RS18180 d171d7a0530c04b0e309c6c1313634f3 173 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 4 172 4.3E-62 T 09-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 CLOSPO_RS18180 d171d7a0530c04b0e309c6c1313634f3 173 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 2 172 4.8E-51 T 09-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 CLOSPO_RS18180 d171d7a0530c04b0e309c6c1313634f3 173 Gene3D G3DSA:3.40.50.300 2 172 1.6E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18180 d171d7a0530c04b0e309c6c1313634f3 173 SUPERFAMILY SSF52540 2 172 1.51E-53 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18180 d171d7a0530c04b0e309c6c1313634f3 173 PIRSF PIRSF015617 1 173 5.8E-63 T 09-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 CLOSPO_RS18180 d171d7a0530c04b0e309c6c1313634f3 173 PANTHER PTHR30069 3 172 9.2E-55 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 PANTHER PTHR32089:SF47 106 409 5.3E-146 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 SUPERFAMILY SSF58104 220 485 3.01E-50 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 PANTHER PTHR32089 438 487 5.3E-146 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 282 470 6.7E-38 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 Gene3D G3DSA:1.10.287.950 427 487 8.1E-4 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 Gene3D G3DSA:1.10.287.950 238 420 7.6E-44 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 PANTHER PTHR32089:SF47 438 487 5.3E-146 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 PANTHER PTHR32089 106 409 5.3E-146 T 09-11-2016 CLOSPO_RS17020 1794026cb6dec4333f2ee035faf0cce7 488 SMART SM00283 216 463 3.1E-36 T 09-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CLOSPO_RS11630 8c922a6a9f0656b43715d76eff3d956e 353 SUPERFAMILY SSF48371 2 284 1.15E-9 T 09-11-2016 IPR016024 Armadillo-type fold GO:0005488 CLOSPO_RS11630 8c922a6a9f0656b43715d76eff3d956e 353 Gene3D G3DSA:1.25.10.10 8 293 1.4E-4 T 09-11-2016 IPR011989 Armadillo-like helical CLOSPO_RS16980 1102638cb8bdc1d803f8a0f916e09a71 189 Gene3D G3DSA:3.40.50.300 2 134 1.1E-6 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16980 1102638cb8bdc1d803f8a0f916e09a71 189 PANTHER PTHR39206 1 185 2.0E-56 T 09-11-2016 CLOSPO_RS16980 1102638cb8bdc1d803f8a0f916e09a71 189 Pfam PF06414 Zeta toxin 6 158 2.7E-5 T 09-11-2016 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CLOSPO_RS16980 1102638cb8bdc1d803f8a0f916e09a71 189 SUPERFAMILY SSF52540 1 135 5.31E-5 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16980 1102638cb8bdc1d803f8a0f916e09a71 189 PANTHER PTHR39206:SF1 1 185 2.0E-56 T 09-11-2016 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 PANTHER PTHR30061 1 424 1.1E-86 T 09-11-2016 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 Pfam PF01547 Bacterial extracellular solute-binding protein 47 247 2.3E-16 T 09-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 PANTHER PTHR30061:SF24 1 424 1.1E-86 T 09-11-2016 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 SUPERFAMILY SSF53850 37 413 4.35E-36 T 09-11-2016 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 Gene3D G3DSA:3.40.190.10 315 362 7.9E-12 T 09-11-2016 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 Gene3D G3DSA:3.40.190.10 35 147 7.9E-12 T 09-11-2016 CLOSPO_RS14190 19cd21e5531900dc17ea99efbe2be10f 424 Gene3D G3DSA:3.40.190.10 149 314 5.5E-20 T 09-11-2016 CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 PANTHER PTHR30337 1 406 7.9E-115 T 09-11-2016 CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 Gene3D G3DSA:3.60.21.10 1 286 2.9E-64 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 PANTHER PTHR30337:SF0 1 406 7.9E-115 T 09-11-2016 CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 292 377 3.8E-6 T 09-11-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 SUPERFAMILY SSF56300 1 348 7.25E-55 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 269 3.4E-54 T 09-11-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CLOSPO_RS15690 643d554156f3802ac76f0cbe7670c6b7 409 Pfam PF00149 Calcineurin-like phosphoesterase 1 240 2.6E-13 T 09-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 SMART SM00382 31 224 1.3E-7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 PANTHER PTHR24220:SF534 3 248 3.6E-127 T 09-11-2016 CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 Pfam PF00005 ABC transporter 24 176 3.5E-30 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 PANTHER PTHR24220 3 248 3.6E-127 T 09-11-2016 CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 Gene3D G3DSA:3.40.50.300 1 234 1.7E-59 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16805 5cdb1a6610eb765a5fbafdbad572a6e7 251 SUPERFAMILY SSF52540 1 232 3.09E-53 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17010 3b7280bba3ea1436d62ff9bcfeb9f16a 86 PANTHER PTHR36121 1 86 1.5E-35 T 09-11-2016 CLOSPO_RS17010 3b7280bba3ea1436d62ff9bcfeb9f16a 86 Pfam PF04994 TfoX C-terminal domain 3 78 1.7E-25 T 09-11-2016 IPR007077 TfoX, C-terminal CLOSPO_RS17010 3b7280bba3ea1436d62ff9bcfeb9f16a 86 Gene3D G3DSA:1.10.150.20 1 84 4.2E-32 T 09-11-2016 CLOSPO_RS17010 3b7280bba3ea1436d62ff9bcfeb9f16a 86 PANTHER PTHR36121:SF1 1 86 1.5E-35 T 09-11-2016 CLOSPO_RS13335 3549f6c2d99e6699d595b93b5a7060be 227 PANTHER PTHR31272 1 227 8.7E-84 T 09-11-2016 CLOSPO_RS13335 3549f6c2d99e6699d595b93b5a7060be 227 PANTHER PTHR31272:SF4 1 227 8.7E-84 T 09-11-2016 CLOSPO_RS13335 3549f6c2d99e6699d595b93b5a7060be 227 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 7 215 2.6E-58 T 09-11-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 PANTHER PTHR10060:SF20 2 259 2.9E-123 T 09-11-2016 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 Pfam PF01026 TatD related DNase 7 256 7.7E-81 T 09-11-2016 IPR001130 TatD family GO:0016788 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 PANTHER PTHR10060 2 259 2.9E-123 T 09-11-2016 IPR001130 TatD family GO:0016788 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 6 256 1.4E-87 T 09-11-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 PIRSF PIRSF005902 1 260 6.8E-87 T 09-11-2016 IPR001130 TatD family GO:0016788 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 SUPERFAMILY SSF51556 4 258 8.65E-88 T 09-11-2016 IPR032466 Metal-dependent hydrolase CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 192 208 - T 09-11-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CLOSPO_RS14340 ad98d9cc51d260305f901215a513093e 264 Gene3D G3DSA:3.20.20.140 2 258 1.0E-94 T 09-11-2016 CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 Pfam PF01368 DHH family 349 504 7.3E-21 T 09-11-2016 IPR001667 DDH domain CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 PIRSF PIRSF026583 1 661 1.9E-217 T 09-11-2016 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 PANTHER PTHR12112:SF18 14 622 1.4E-261 T 09-11-2016 CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 Pfam PF02272 DHHA1 domain 595 649 2.8E-10 T 09-11-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 Gene3D G3DSA:3.90.1640.10 348 540 2.3E-42 T 09-11-2016 CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 PANTHER PTHR12112 14 622 1.4E-261 T 09-11-2016 CLOSPO_RS14680 7316383a29e8d26ccb4eefd48855f2bc 661 SUPERFAMILY SSF64182 349 647 8.76E-66 T 09-11-2016 CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 PANTHER PTHR24220 5 246 1.7E-103 T 09-11-2016 CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 SMART SM00382 28 213 1.6E-7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 Pfam PF00005 ABC transporter 19 162 1.6E-36 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 SUPERFAMILY SSF52540 3 223 7.43E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 Gene3D G3DSA:3.40.50.300 3 228 8.8E-77 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS15815 37bd380fec600495b13354436be8cc42 311 PANTHER PTHR24220:SF501 5 246 1.7E-103 T 09-11-2016 CLOSPO_RS19070 3699bafc6dc87922e530f8c71ea40a8f 201 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 7 115 6.7E-23 T 09-11-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 CLOSPO_RS19070 3699bafc6dc87922e530f8c71ea40a8f 201 PANTHER PTHR33988:SF2 1 120 6.2E-25 T 09-11-2016 CLOSPO_RS19070 3699bafc6dc87922e530f8c71ea40a8f 201 SUPERFAMILY SSF50118 6 118 3.05E-27 T 09-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CLOSPO_RS19070 3699bafc6dc87922e530f8c71ea40a8f 201 PANTHER PTHR33988 1 120 6.2E-25 T 09-11-2016 CLOSPO_RS19070 3699bafc6dc87922e530f8c71ea40a8f 201 Gene3D G3DSA:2.30.30.110 5 119 2.9E-31 T 09-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CLOSPO_RS17815 af4c17e6b910a7e1d877e3da9b13bee0 370 SUPERFAMILY SSF56235 100 237 2.37E-18 T 09-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal CLOSPO_RS17815 af4c17e6b910a7e1d877e3da9b13bee0 370 Gene3D G3DSA:3.60.60.10 92 346 2.5E-32 T 09-11-2016 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 CLOSPO_RS17815 af4c17e6b910a7e1d877e3da9b13bee0 370 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 102 334 4.9E-35 T 09-11-2016 IPR005079 Peptidase C45 CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 Gene3D G3DSA:3.40.50.10740 3 159 2.2E-52 T 09-11-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 SUPERFAMILY SSF52317 2 160 1.6E-51 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 Gene3D G3DSA:3.50.30.60 170 298 2.2E-45 T 09-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 PANTHER PTHR30237 1 299 2.5E-133 T 09-11-2016 CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 PIRSF PIRSF028757 1 302 6.4E-93 T 09-11-2016 IPR003507 Peptidase family S66 CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 PANTHER PTHR30237:SF2 1 299 2.5E-133 T 09-11-2016 CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 SUPERFAMILY SSF141986 138 296 5.23E-45 T 09-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain CLOSPO_RS14485 c4d23abe1df513553206787a5e75ddad 302 Pfam PF02016 LD-carboxypeptidase 12 290 1.5E-82 T 09-11-2016 IPR003507 Peptidase family S66 CLOSPO_RS13450 3830acafff4089b12b874004ec11a61a 539 Gene3D G3DSA:1.10.606.10 30 539 4.2E-194 T 09-11-2016 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 CLOSPO_RS13450 3830acafff4089b12b874004ec11a61a 539 Pfam PF01569 PAP2 superfamily 366 515 6.3E-8 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS13450 3830acafff4089b12b874004ec11a61a 539 SUPERFAMILY SSF48317 41 536 1.31E-112 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS18415 926c1db501e789fc3cdba343f61de952 181 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 160 1.1E-24 T 09-11-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type CLOSPO_RS18415 926c1db501e789fc3cdba343f61de952 181 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 164 2.3E-30 T 09-11-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 CLOSPO_RS18415 926c1db501e789fc3cdba343f61de952 181 SUPERFAMILY SSF56300 1 177 3.24E-39 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS18415 926c1db501e789fc3cdba343f61de952 181 PANTHER PTHR11124 1 181 1.2E-65 T 09-11-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 CLOSPO_RS18415 926c1db501e789fc3cdba343f61de952 181 Gene3D G3DSA:3.60.21.10 1 168 6.2E-43 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS18415 926c1db501e789fc3cdba343f61de952 181 PANTHER PTHR11124:SF14 1 181 1.2E-65 T 09-11-2016 CLOSPO_RS17195 3fc92ad730fd6dc065b702ee70dd3553 356 PIRSF PIRSF005508 1 356 1.0E-132 T 09-11-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CLOSPO_RS17195 3fc92ad730fd6dc065b702ee70dd3553 356 PANTHER PTHR10361 4 349 2.0E-137 T 09-11-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CLOSPO_RS17195 3fc92ad730fd6dc065b702ee70dd3553 356 Pfam PF01758 Sodium Bile acid symporter family 57 254 3.8E-47 T 09-11-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CLOSPO_RS17195 3fc92ad730fd6dc065b702ee70dd3553 356 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 12 342 2.4E-117 T 09-11-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CLOSPO_RS17195 3fc92ad730fd6dc065b702ee70dd3553 356 PANTHER PTHR10361:SF31 4 349 2.0E-137 T 09-11-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CLOSPO_RS17535 d182d9832396afeed8da0b156f2f5ea9 450 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 189 436 4.3E-58 T 09-11-2016 IPR018763 Protein of unknown function DUF2334 CLOSPO_RS17535 d182d9832396afeed8da0b156f2f5ea9 450 Gene3D G3DSA:3.20.20.370 261 450 1.2E-4 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS17535 d182d9832396afeed8da0b156f2f5ea9 450 Pfam PF07833 Copper amine oxidase N-terminal domain 80 166 1.6E-8 T 09-11-2016 IPR012854 Copper amine oxidase-like, N-terminal CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 Gene3D G3DSA:3.40.50.720 1 163 2.1E-61 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 SUPERFAMILY SSF56327 169 441 7.02E-70 T 09-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 3.5E-38 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 3.5E-38 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 3.5E-38 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 3.5E-38 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 3.5E-38 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 3.5E-38 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 415 1.3E-45 T 09-11-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 SUPERFAMILY SSF51735 3 162 3.66E-49 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PANTHER PTHR32092:SF7 1 441 2.8E-301 T 09-11-2016 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 PANTHER PTHR32092 1 441 2.8E-301 T 09-11-2016 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 Gene3D G3DSA:3.90.110.10 168 440 1.3E-88 T 09-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 170 - T 09-11-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CLOSPO_RS13295 3528ca2440eb1df2e04fafefa256ed13 441 Pfam PF02056 Family 4 glycosyl hydrolase 6 180 2.2E-48 T 09-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 PANTHER PTHR33154 4 100 4.0E-46 T 09-11-2016 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 Gene3D G3DSA:1.10.10.10 4 93 9.5E-31 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 PANTHER PTHR33154:SF3 4 100 4.0E-46 T 09-11-2016 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 33 51 - T 09-11-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 SUPERFAMILY SSF46785 4 88 5.87E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 Pfam PF01022 Bacterial regulatory protein, arsR family 17 63 4.3E-17 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 SMART SM00418 10 88 2.1E-27 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 1.9E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 1.9E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.9E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17180 678313eb99f262b25dafd4951f8f77f3 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 1.9E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS18300 93536d855b2895221edee536addf109e 175 Pfam PF00583 Acetyltransferase (GNAT) family 61 151 3.4E-14 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18300 93536d855b2895221edee536addf109e 175 PANTHER PTHR23091 1 171 8.8E-22 T 09-11-2016 CLOSPO_RS18300 93536d855b2895221edee536addf109e 175 Gene3D G3DSA:3.40.630.30 1 175 1.8E-38 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18300 93536d855b2895221edee536addf109e 175 SUPERFAMILY SSF55729 1 161 8.1E-31 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 61 79 - T 09-11-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 Pfam PF01022 Bacterial regulatory protein, arsR family 46 90 1.2E-19 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 PANTHER PTHR33154 1 121 4.9E-35 T 09-11-2016 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 2.3E-21 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 2.3E-21 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 2.3E-21 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.3E-21 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 SUPERFAMILY SSF46785 25 117 1.03E-28 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 SMART SM00418 38 116 8.3E-35 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS15710 a12f32ad2c8d16acaac952d9dc355b5b 121 Gene3D G3DSA:1.10.10.10 8 120 2.3E-39 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18960 cb8d56ea3f117098a65a4d90c4460de7 173 PANTHER PTHR30055 9 150 2.4E-14 T 09-11-2016 CLOSPO_RS18960 cb8d56ea3f117098a65a4d90c4460de7 173 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 1.3E-9 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS18960 cb8d56ea3f117098a65a4d90c4460de7 173 SUPERFAMILY SSF46689 7 70 6.8E-13 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS18960 cb8d56ea3f117098a65a4d90c4460de7 173 Gene3D G3DSA:1.10.357.10 9 151 3.1E-20 T 09-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CLOSPO_RS13635 51193c45a24b6fc9d0d5844e8bfec5b5 386 PANTHER PTHR35788:SF1 9 385 1.7E-132 T 09-11-2016 CLOSPO_RS13635 51193c45a24b6fc9d0d5844e8bfec5b5 386 PANTHER PTHR35788 9 385 1.7E-132 T 09-11-2016 CLOSPO_RS13635 51193c45a24b6fc9d0d5844e8bfec5b5 386 Pfam PF04294 VanW like protein 255 384 8.9E-51 T 09-11-2016 IPR007391 Vancomycin resistance VanW CLOSPO_RS13635 51193c45a24b6fc9d0d5844e8bfec5b5 386 Pfam PF12229 Putative peptidoglycan binding domain 102 216 1.7E-19 T 09-11-2016 IPR022029 Putative peptidoglycan binding domain CLOSPO_RS13405 f1cc8da71f2474444a25f9e0b1099a9a 640 PIRSF PIRSF018968 1 635 3.2E-91 T 09-11-2016 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CLOSPO_RS13405 f1cc8da71f2474444a25f9e0b1099a9a 640 Pfam PF02687 FtsX-like permease family 62 178 1.7E-10 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS13405 f1cc8da71f2474444a25f9e0b1099a9a 640 PANTHER PTHR30489 1 622 2.6E-28 T 09-11-2016 CLOSPO_RS18580 a6822636ff67f0e6fdce3d54504593c6 69 Pfam PF04023 FeoA domain 1 69 2.8E-14 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS18580 a6822636ff67f0e6fdce3d54504593c6 69 PANTHER PTHR33238 1 69 1.8E-17 T 09-11-2016 CLOSPO_RS18580 a6822636ff67f0e6fdce3d54504593c6 69 SUPERFAMILY SSF50037 3 69 1.4E-11 T 09-11-2016 IPR008988 Transcriptional repressor, C-terminal CLOSPO_RS18580 a6822636ff67f0e6fdce3d54504593c6 69 SMART SM00899 1 69 4.8E-8 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 Gene3D G3DSA:3.20.20.70 1 247 1.0E-106 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 Pfam PF00121 Triosephosphate isomerase 5 246 3.7E-95 T 09-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 09-11-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 SUPERFAMILY SSF51351 1 247 4.71E-98 T 09-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 39.271 T 09-11-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 PANTHER PTHR21139 1 247 2.1E-128 T 09-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 CLOSPO_RS13565 6dcda1465145dfddb20b97bb6a638d22 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 239 4.0E-58 T 09-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 CLOSPO_RS17475 7ffcfae4337e09c4b393f37d79b8e216 437 PANTHER PTHR30588 1 436 1.6E-202 T 09-11-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CLOSPO_RS17475 7ffcfae4337e09c4b393f37d79b8e216 437 PANTHER PTHR30588:SF0 1 436 1.6E-202 T 09-11-2016 CLOSPO_RS17475 7ffcfae4337e09c4b393f37d79b8e216 437 Pfam PF05525 Branched-chain amino acid transport protein 6 423 3.1E-120 T 09-11-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CLOSPO_RS17475 7ffcfae4337e09c4b393f37d79b8e216 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 412 1.4E-103 T 09-11-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 PIRSF PIRSF006468 1 341 4.6E-123 T 09-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 PANTHER PTHR11825 6 339 8.9E-157 T 09-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 Pfam PF01063 Amino-transferase class IV 57 294 9.7E-37 T 09-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 SUPERFAMILY SSF56752 5 337 1.7E-105 T 09-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 ProSitePatterns PS00770 Aminotransferases class-IV signature. 221 250 - T 09-11-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 Gene3D G3DSA:3.30.470.10 3 163 4.3E-68 T 09-11-2016 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 Gene3D G3DSA:3.20.10.10 164 326 8.5E-58 T 09-11-2016 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 PANTHER PTHR11825:SF2 6 339 8.9E-157 T 09-11-2016 CLOSPO_RS17910 fa192255fea9aa66c84e31612c88b20f 341 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 32 340 4.9E-140 T 09-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 CLOSPO_RS12725 f143adde55bff4999e151d48e6f383b7 276 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 13 274 4.3E-64 T 09-11-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CLOSPO_RS12725 f143adde55bff4999e151d48e6f383b7 276 PANTHER PTHR30425:SF0 1 275 1.3E-87 T 09-11-2016 CLOSPO_RS12725 f143adde55bff4999e151d48e6f383b7 276 Gene3D G3DSA:1.10.3720.10 8 275 8.5E-35 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS12725 f143adde55bff4999e151d48e6f383b7 276 SUPERFAMILY SSF161098 10 270 1.59E-32 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS12725 f143adde55bff4999e151d48e6f383b7 276 PANTHER PTHR30425 1 275 1.3E-87 T 09-11-2016 CLOSPO_RS12725 f143adde55bff4999e151d48e6f383b7 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 272 1.3E-19 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS12985 ab7f9b3edc3cb45aec6c53d77efcfe82 209 Pfam PF04647 Accessory gene regulator B 5 195 5.7E-39 T 09-11-2016 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CLOSPO_RS12985 ab7f9b3edc3cb45aec6c53d77efcfe82 209 SMART SM00793 6 208 3.3E-18 T 09-11-2016 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 277 1.0E-94 T 09-11-2016 IPR003797 DegV CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 PANTHER PTHR33434 1 279 6.1E-114 T 09-11-2016 CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 276 3.1E-95 T 09-11-2016 IPR003797 DegV CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 Gene3D G3DSA:3.40.50.10170 3 150 2.9E-53 T 09-11-2016 CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 SUPERFAMILY SSF82549 3 278 4.19E-86 T 09-11-2016 CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 PANTHER PTHR33434:SF3 1 279 6.1E-114 T 09-11-2016 CLOSPO_RS13615 963a8a05ae7ed770a486a999dabad2c2 279 Gene3D G3DSA:3.30.1180.10 154 277 9.1E-33 T 09-11-2016 CLOSPO_RS14535 b5ffcbe5564a3489b11f930699286673 68 PANTHER PTHR32319 5 68 6.1E-27 T 09-11-2016 CLOSPO_RS14535 b5ffcbe5564a3489b11f930699286673 68 SUPERFAMILY SSF55174 1 67 1.44E-19 T 09-11-2016 CLOSPO_RS14535 b5ffcbe5564a3489b11f930699286673 68 Gene3D G3DSA:3.10.290.10 1 67 4.3E-27 T 09-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 CLOSPO_RS14535 b5ffcbe5564a3489b11f930699286673 68 Pfam PF13275 S4 domain 4 67 7.3E-26 T 09-11-2016 CLOSPO_RS14535 b5ffcbe5564a3489b11f930699286673 68 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 62 2.4E-26 T 09-11-2016 IPR014330 RNA-binding S4-related,YaaA CLOSPO_RS15095 50240b44cc341cf33e509441752cca36 239 SUPERFAMILY SSF142823 1 234 5.23E-79 T 09-11-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CLOSPO_RS15095 50240b44cc341cf33e509441752cca36 239 PANTHER PTHR37311 1 235 5.6E-65 T 09-11-2016 CLOSPO_RS15095 50240b44cc341cf33e509441752cca36 239 Gene3D G3DSA:3.90.1560.10 8 236 1.9E-80 T 09-11-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CLOSPO_RS15095 50240b44cc341cf33e509441752cca36 239 Hamap MF_00490 2-phosphosulfolactate phosphatase [comB]. 5 238 32.239 T 09-11-2016 IPR022995 Probable 2-phosphosulpholactate phosphatase GO:0019295|GO:0050532 KEGG: 00680+3.1.3.71 CLOSPO_RS15095 50240b44cc341cf33e509441752cca36 239 PANTHER PTHR37311:SF1 1 235 5.6E-65 T 09-11-2016 CLOSPO_RS15095 50240b44cc341cf33e509441752cca36 239 Pfam PF04029 2-phosphosulpholactate phosphatase 10 231 6.7E-82 T 09-11-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CLOSPO_RS14370 cdff9adf9c30cf5e095c7a180ca55329 172 Pfam PF07670 Nucleoside recognition 43 143 7.0E-8 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS14370 cdff9adf9c30cf5e095c7a180ca55329 172 PANTHER PTHR35793 1 172 1.8E-105 T 09-11-2016 CLOSPO_RS18825 3689fbd25d9fdda1ee0d271b3ca679c3 194 PANTHER PTHR37171:SF1 1 190 3.9E-30 T 09-11-2016 CLOSPO_RS18825 3689fbd25d9fdda1ee0d271b3ca679c3 194 SUPERFAMILY SSF56112 20 139 1.11E-13 T 09-11-2016 IPR011009 Protein kinase-like domain CLOSPO_RS18825 3689fbd25d9fdda1ee0d271b3ca679c3 194 PANTHER PTHR37171 1 190 3.9E-30 T 09-11-2016 CLOSPO_RS18825 3689fbd25d9fdda1ee0d271b3ca679c3 194 Gene3D G3DSA:3.30.200.20 19 102 1.0E-6 T 09-11-2016 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 1 53 2.7E-17 T 09-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 PANTHER PTHR22573 1 145 2.5E-42 T 09-11-2016 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 PANTHER PTHR22573:SF15 1 145 2.5E-42 T 09-11-2016 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 SUPERFAMILY SSF53738 1 100 8.83E-23 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 78 142 3.0E-7 T 09-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 Gene3D G3DSA:3.40.120.10 1 88 3.0E-20 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 13 22 - T 09-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 112 7.1E-5 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 12 26 7.1E-5 T 09-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 SUPERFAMILY SSF53738 77 145 1.71E-12 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS07320 0563b921f2420d479b823521ef218529 145 Gene3D G3DSA:3.40.120.10 95 144 1.2E-13 T 09-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOSPO_RS16865 2877f0baae5849c5b94dba58e979a22e 329 SUPERFAMILY SSF53807 51 321 4.71E-48 T 09-11-2016 CLOSPO_RS16865 2877f0baae5849c5b94dba58e979a22e 329 PANTHER PTHR30532 1 329 6.6E-84 T 09-11-2016 CLOSPO_RS16865 2877f0baae5849c5b94dba58e979a22e 329 PANTHER PTHR30532:SF1 1 329 6.6E-84 T 09-11-2016 CLOSPO_RS16865 2877f0baae5849c5b94dba58e979a22e 329 Pfam PF01497 Periplasmic binding protein 70 306 6.5E-32 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS16865 2877f0baae5849c5b94dba58e979a22e 329 Gene3D G3DSA:3.40.50.1980 182 327 1.2E-21 T 09-11-2016 CLOSPO_RS16865 2877f0baae5849c5b94dba58e979a22e 329 Gene3D G3DSA:3.40.50.1980 49 181 1.4E-26 T 09-11-2016 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 09-11-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.8E-17 T 09-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.8E-17 T 09-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.8E-17 T 09-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 SUPERFAMILY SSF47729 1 90 9.27E-33 T 09-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 Gene3D G3DSA:4.10.520.10 1 91 3.8E-38 T 09-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 PANTHER PTHR33175 1 90 2.9E-41 T 09-11-2016 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 SMART SM00411 1 90 6.1E-44 T 09-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOSPO_RS15195 24a3fc4f61e0901787098451888372e0 92 Pfam PF00216 Bacterial DNA-binding protein 1 90 7.4E-34 T 09-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOSPO_RS18280 305f9bb9e5ed08742c8cad3b7f92a561 340 Pfam PF01497 Periplasmic binding protein 76 311 2.0E-27 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS18280 305f9bb9e5ed08742c8cad3b7f92a561 340 Gene3D G3DSA:3.40.50.1980 201 339 2.3E-31 T 09-11-2016 CLOSPO_RS18280 305f9bb9e5ed08742c8cad3b7f92a561 340 SUPERFAMILY SSF53807 63 340 9.03E-46 T 09-11-2016 CLOSPO_RS18280 305f9bb9e5ed08742c8cad3b7f92a561 340 Gene3D G3DSA:3.40.50.1980 71 198 1.9E-9 T 09-11-2016 CLOSPO_RS18280 305f9bb9e5ed08742c8cad3b7f92a561 340 PANTHER PTHR30535 63 337 5.5E-169 T 09-11-2016 CLOSPO_RS18280 305f9bb9e5ed08742c8cad3b7f92a561 340 PANTHER PTHR30535:SF14 63 337 5.5E-169 T 09-11-2016 CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 PIRSF PIRSF037226 1 386 1.1E-94 T 09-11-2016 IPR017144 Peptidase M20A, amidohydrolase, predicted CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 PANTHER PTHR30575 1 386 5.4E-127 T 09-11-2016 CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 SUPERFAMILY SSF53187 276 371 8.7E-44 T 09-11-2016 CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 SUPERFAMILY SSF53187 3 177 8.7E-44 T 09-11-2016 CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 Gene3D G3DSA:3.40.630.10 273 381 1.7E-43 T 09-11-2016 CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 Gene3D G3DSA:3.40.630.10 1 165 1.7E-43 T 09-11-2016 CLOSPO_RS14470 6e8add3e158ce6a6bf2e5c1da16ef516 386 PANTHER PTHR30575:SF0 1 386 5.4E-127 T 09-11-2016 CLOSPO_RS14615 1e66528587ad7b7cd019d2f308f770b4 193 Pfam PF06866 Protein of unknown function (DUF1256) 15 172 5.2E-65 T 09-11-2016 IPR009665 Protein of unknown function DUF1256 CLOSPO_RS14615 1e66528587ad7b7cd019d2f308f770b4 193 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 34 173 6.5E-68 T 09-11-2016 IPR009665 Protein of unknown function DUF1256 CLOSPO_RS14615 1e66528587ad7b7cd019d2f308f770b4 193 SUPERFAMILY SSF53163 15 181 4.71E-52 T 09-11-2016 IPR023430 Peptidase HybD-like domain CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 3.1E-96 T 09-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.389 T 09-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 PANTHER PTHR21090 1 416 1.9E-192 T 09-11-2016 CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 Gene3D G3DSA:3.65.10.10 21 220 3.6E-60 T 09-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 2.4E-168 T 09-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 Gene3D G3DSA:3.65.10.10 221 415 8.7E-63 T 09-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOSPO_RS15035 605df10f6876e7aba4a561e71032ca95 417 SUPERFAMILY SSF55205 1 416 2.62E-134 T 09-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CLOSPO_RS17775 a27f6aba5b26104c82d362ee7af0ca4a 286 SUPERFAMILY SSF47413 60 109 7.17E-11 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17775 a27f6aba5b26104c82d362ee7af0ca4a 286 Pfam PF01381 Helix-turn-helix 57 108 2.6E-8 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17775 a27f6aba5b26104c82d362ee7af0ca4a 286 SMART SM00530 54 108 8.7E-8 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17775 a27f6aba5b26104c82d362ee7af0ca4a 286 Gene3D G3DSA:1.10.260.40 55 109 5.5E-13 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS12475 30140ace977aaddd79f98b79756925c3 41 Pfam PF11490 DNA polymerase III polC-type N-terminus II 3 41 4.3E-5 T 09-11-2016 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 SMART SM00530 11 67 2.1E-9 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 SUPERFAMILY SSF47413 7 69 3.22E-13 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 PANTHER PTHR10245:SF22 9 283 1.6E-19 T 09-11-2016 CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 Pfam PF06114 Domain of unknown function (DUF955) 179 280 1.8E-14 T 09-11-2016 IPR010359 HTH domain, IrrE-type CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 Pfam PF01381 Helix-turn-helix 12 63 5.6E-9 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 Gene3D G3DSA:1.10.260.40 9 74 4.5E-15 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS13485 dd6f1295ca1efbbcaf13f669941d3263 392 PANTHER PTHR10245 9 283 1.6E-19 T 09-11-2016 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 PANTHER PTHR31760 1 238 5.7E-88 T 09-11-2016 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 PANTHER PTHR31760:SF0 1 238 5.7E-88 T 09-11-2016 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 PIRSF PIRSF003078 1 221 2.2E-57 T 09-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 215 28.419 T 09-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 SUPERFAMILY SSF53335 5 239 6.99E-49 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 218 2.3E-56 T 09-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 Pfam PF02527 rRNA small subunit methyltransferase G 23 200 7.8E-56 T 09-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOSPO_RS14585 911ebd1bac4f6df007724ec65217db79 239 Gene3D G3DSA:3.40.50.150 5 238 2.1E-74 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 09-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Gene3D G3DSA:3.40.50.620 196 245 9.3E-48 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Gene3D G3DSA:3.40.50.620 4 70 9.3E-48 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PANTHER PTHR11451:SF26 3 340 1.3E-112 T 09-11-2016 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 476 2.8E-162 T 09-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 321 1.2E-105 T 09-11-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PANTHER PTHR11451 3 340 1.3E-112 T 09-11-2016 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 SUPERFAMILY SSF52374 4 314 4.83E-112 T 09-11-2016 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Gene3D G3DSA:3.90.800.10 71 195 3.9E-42 T 09-11-2016 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 478 31.408 T 09-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 5.7E-25 T 09-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 5.7E-25 T 09-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 5.7E-25 T 09-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 5.7E-25 T 09-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 5.7E-25 T 09-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 SUPERFAMILY SSF48163 315 478 1.57E-36 T 09-11-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Gene3D G3DSA:1.10.10.350 376 476 4.9E-24 T 09-11-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CLOSPO_RS18980 574b64647124e828a90e19ba9997a582 485 Gene3D G3DSA:1.10.1160.10 248 330 4.9E-34 T 09-11-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 CLOSPO_RS15560 6880036cffe552dc862dfb23ca213da4 211 SUPERFAMILY SSF161098 11 196 3.14E-44 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS15560 6880036cffe552dc862dfb23ca213da4 211 PANTHER PTHR30614 1 211 6.3E-125 T 09-11-2016 CLOSPO_RS15560 6880036cffe552dc862dfb23ca213da4 211 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 9.1E-29 T 09-11-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CLOSPO_RS15560 6880036cffe552dc862dfb23ca213da4 211 Gene3D G3DSA:1.10.3720.10 11 209 1.2E-48 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS15560 6880036cffe552dc862dfb23ca213da4 211 PANTHER PTHR30614:SF11 1 211 6.3E-125 T 09-11-2016 CLOSPO_RS15560 6880036cffe552dc862dfb23ca213da4 211 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 1.4E-25 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS15425 8d7b4464bcc1a4693cf6cc0218b1848c 241 Gene3D G3DSA:3.40.1130.10 59 233 4.3E-29 T 09-11-2016 CLOSPO_RS15425 8d7b4464bcc1a4693cf6cc0218b1848c 241 SUPERFAMILY SSF69593 52 236 2.35E-42 T 09-11-2016 CLOSPO_RS15425 8d7b4464bcc1a4693cf6cc0218b1848c 241 Pfam PF01553 Acyltransferase 58 183 2.5E-29 T 09-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CLOSPO_RS15425 8d7b4464bcc1a4693cf6cc0218b1848c 241 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 56 183 2.2E-32 T 09-11-2016 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|Reactome: REACT_22258|UniPathway: UPA00557 CLOSPO_RS15425 8d7b4464bcc1a4693cf6cc0218b1848c 241 PANTHER PTHR10434 47 241 1.8E-53 T 09-11-2016 CLOSPO_RS15425 8d7b4464bcc1a4693cf6cc0218b1848c 241 SMART SM00563 72 186 4.7E-35 T 09-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CLOSPO_RS12665 909ccad992a5f6778347b0ab895a6779 350 Gene3D G3DSA:1.10.3210.10 124 286 3.3E-22 T 09-11-2016 IPR006674 HD domain CLOSPO_RS12665 909ccad992a5f6778347b0ab895a6779 350 TIGRFAM TIGR00277 HDIG: HDIG domain 152 218 7.2E-8 T 09-11-2016 IPR006675 HDIG domain CLOSPO_RS12665 909ccad992a5f6778347b0ab895a6779 350 Pfam PF01966 HD domain 127 249 5.0E-18 T 09-11-2016 IPR006674 HD domain CLOSPO_RS12665 909ccad992a5f6778347b0ab895a6779 350 SUPERFAMILY SSF109604 118 287 6.68E-34 T 09-11-2016 CLOSPO_RS12665 909ccad992a5f6778347b0ab895a6779 350 SMART SM00471 123 259 2.3E-10 T 09-11-2016 IPR003607 HD/PDEase domain CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 PANTHER PTHR17490 4 348 9.8E-130 T 09-11-2016 CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 344 3.0E-27 T 09-11-2016 IPR005145 Putative GTP-binding controlling metal-binding domain CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 PANTHER PTHR17490:SF3 4 348 9.8E-130 T 09-11-2016 CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 SUPERFAMILY SSF55821 6 211 2.35E-65 T 09-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 PIRSF PIRSF004930 1 350 3.2E-131 T 09-11-2016 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 Gene3D G3DSA:3.90.870.10 4 206 1.7E-77 T 09-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 Pfam PF01300 Telomere recombination 24 199 3.7E-58 T 09-11-2016 IPR006070 YrdC-like domain GO:0003725 CLOSPO_RS14015 ecb5fc9a1ab73079e3dab092e6610b68 351 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 208 2.2E-70 T 09-11-2016 IPR006070 YrdC-like domain GO:0003725 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 SMART SM00862 151 226 3.4E-23 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 Gene3D G3DSA:1.10.10.10 132 226 6.4E-29 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 SMART SM00448 3 113 5.0E-40 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 Pfam PF00072 Response regulator receiver domain 5 113 3.6E-24 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 4.1E-24 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 SUPERFAMILY SSF52172 2 127 3.13E-37 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 SUPERFAMILY SSF46894 133 226 4.54E-27 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 PANTHER PTHR26402:SF578 3 227 1.6E-74 T 09-11-2016 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 Gene3D G3DSA:3.40.50.2300 2 127 1.6E-34 T 09-11-2016 CLOSPO_RS16400 8765e7ac7d49a5f461b89aa92f9f231d 227 PANTHER PTHR26402 3 227 1.6E-74 T 09-11-2016 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 31.219 T 09-11-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 SUPERFAMILY SSF75217 1 157 3.09E-59 T 09-11-2016 IPR029028 Alpha/beta knot methyltransferases CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 PANTHER PTHR33603 1 159 4.9E-69 T 09-11-2016 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 1.8E-60 T 09-11-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 1.8E-53 T 09-11-2016 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 PIRSF PIRSF004505 1 159 2.7E-58 T 09-11-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 PANTHER PTHR33603:SF1 1 159 4.9E-69 T 09-11-2016 CLOSPO_RS15015 5f41afe96b38251d658fc34d18dd59af 159 Gene3D G3DSA:3.40.1280.10 1 159 6.3E-64 T 09-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOSPO_RS17700 faea9f20620f0e85dcfaa0ddee31886a 148 Pfam PF13673 Acetyltransferase (GNAT) domain 55 139 6.4E-14 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS17700 faea9f20620f0e85dcfaa0ddee31886a 148 Gene3D G3DSA:3.40.630.30 7 146 1.7E-19 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17700 faea9f20620f0e85dcfaa0ddee31886a 148 PANTHER PTHR23091:SF277 1 132 1.1E-54 T 09-11-2016 CLOSPO_RS17700 faea9f20620f0e85dcfaa0ddee31886a 148 SUPERFAMILY SSF55729 9 143 5.41E-19 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17700 faea9f20620f0e85dcfaa0ddee31886a 148 PANTHER PTHR23091 1 132 1.1E-54 T 09-11-2016 CLOSPO_RS05050 183533bc8ba3dc396b3f1a9af3314689 112 SUPERFAMILY SSF51905 3 75 1.84E-8 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS05050 183533bc8ba3dc396b3f1a9af3314689 112 PANTHER PTHR11938 2 74 1.7E-34 T 09-11-2016 CLOSPO_RS05050 183533bc8ba3dc396b3f1a9af3314689 112 Gene3D G3DSA:3.50.50.60 13 76 4.9E-9 T 09-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOSPO_RS05050 183533bc8ba3dc396b3f1a9af3314689 112 PANTHER PTHR11938:SF70 2 74 1.7E-34 T 09-11-2016 CLOSPO_RS17770 f9c74b4a6be6e5c9616dd57aba9a12f2 317 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 316 6.7E-87 T 09-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS17770 f9c74b4a6be6e5c9616dd57aba9a12f2 317 PANTHER PTHR22926:SF5 1 313 8.6E-131 T 09-11-2016 CLOSPO_RS17770 f9c74b4a6be6e5c9616dd57aba9a12f2 317 Pfam PF00953 Glycosyl transferase family 4 77 244 4.2E-34 T 09-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS17770 f9c74b4a6be6e5c9616dd57aba9a12f2 317 PANTHER PTHR22926 1 313 8.6E-131 T 09-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS17770 f9c74b4a6be6e5c9616dd57aba9a12f2 317 ProSitePatterns PS01348 MraY family signature 2. 164 175 - T 09-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS17770 f9c74b4a6be6e5c9616dd57aba9a12f2 317 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 317 20.256 T 09-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 Gene3D G3DSA:3.40.309.10 225 408 3.8E-63 T 09-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 SUPERFAMILY SSF53720 4 437 4.97E-115 T 09-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 PANTHER PTHR11699 1 444 8.9E-177 T 09-11-2016 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 Gene3D G3DSA:3.40.605.10 3 224 3.8E-51 T 09-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 Pfam PF00171 Aldehyde dehydrogenase family 15 428 9.4E-81 T 09-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 PIRSF PIRSF036492 1 456 8.5E-188 T 09-11-2016 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 09-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 09-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CLOSPO_RS19005 f0343804a1ccc54cd523cc064c488131 456 PANTHER PTHR11699:SF119 1 444 8.9E-177 T 09-11-2016 CLOSPO_RS18410 ad91e857fe5bdb4d01f13cb2ca3ba5a8 271 Pfam PF00561 alpha/beta hydrolase fold 21 257 2.2E-20 T 09-11-2016 IPR000073 Alpha/beta hydrolase fold-1 CLOSPO_RS18410 ad91e857fe5bdb4d01f13cb2ca3ba5a8 271 PANTHER PTHR10992 8 143 1.4E-48 T 09-11-2016 CLOSPO_RS18410 ad91e857fe5bdb4d01f13cb2ca3ba5a8 271 PANTHER PTHR10992 173 271 1.4E-48 T 09-11-2016 CLOSPO_RS18410 ad91e857fe5bdb4d01f13cb2ca3ba5a8 271 Gene3D G3DSA:3.40.50.1820 5 271 6.6E-62 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS18410 ad91e857fe5bdb4d01f13cb2ca3ba5a8 271 SUPERFAMILY SSF53474 3 269 3.27E-55 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 468 592 8.8E-48 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 Gene3D G3DSA:2.70.70.10 465 612 2.9E-56 T 09-11-2016 CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 469 588 4.3E-41 T 09-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 Pfam PF02378 Phosphotransferase system, EIIC 108 385 8.3E-33 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 Gene3D G3DSA:3.30.1360.60 1 81 2.5E-28 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 SUPERFAMILY SSF55604 6 80 1.44E-21 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 PANTHER PTHR30175:SF9 1 563 0.0 T 09-11-2016 CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 613 5.7E-238 T 09-11-2016 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 SUPERFAMILY SSF51261 467 611 4.71E-50 T 09-11-2016 IPR011055 Duplicated hybrid motif CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 Pfam PF00367 phosphotransferase system, EIIB 9 41 1.2E-14 T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS16730 f2bfd83f181f1b9def420f16456a8fd2 613 PANTHER PTHR30175 1 563 0.0 T 09-11-2016 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 SUPERFAMILY SSF53187 26 76 7.93E-51 T 09-11-2016 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 SUPERFAMILY SSF53187 197 406 7.93E-51 T 09-11-2016 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 Pfam PF04389 Peptidase family M28 213 403 1.1E-41 T 09-11-2016 IPR007484 Peptidase M28 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 Gene3D G3DSA:3.40.630.10 212 407 6.8E-50 T 09-11-2016 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 Gene3D G3DSA:3.40.630.10 26 85 6.8E-50 T 09-11-2016 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 PANTHER PTHR12147 30 68 1.4E-38 T 09-11-2016 CLOSPO_RS13835 ee3147d6c1de1860e38bd1f4339dbdec 454 PANTHER PTHR12147 154 398 1.4E-38 T 09-11-2016 CLOSPO_RS18050 4229a1f870f30af38024fa323566176b 208 Gene3D G3DSA:3.40.50.10230 4 207 1.9E-84 T 09-11-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CLOSPO_RS18050 4229a1f870f30af38024fa323566176b 208 Pfam PF02570 Precorrin-8X methylmutase 10 204 1.2E-78 T 09-11-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CLOSPO_RS18050 4229a1f870f30af38024fa323566176b 208 PANTHER PTHR32439 3 208 1.3E-80 T 09-11-2016 CLOSPO_RS18050 4229a1f870f30af38024fa323566176b 208 SUPERFAMILY SSF63965 10 207 1.83E-71 T 09-11-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 SUPERFAMILY SSF52540 328 569 1.22E-89 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 Gene3D G3DSA:1.20.1560.10 15 325 2.9E-36 T 09-11-2016 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 SMART SM00382 358 550 3.8E-16 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 Pfam PF00005 ABC transporter 349 498 4.4E-35 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 PANTHER PTHR24222:SF29 1 569 0.0 T 09-11-2016 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 SUPERFAMILY SSF90123 15 328 5.23E-46 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 Gene3D G3DSA:3.40.50.300 334 563 1.1E-83 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 PANTHER PTHR24222 1 569 0.0 T 09-11-2016 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS18735 17fc059165cb133fab1871a023cc943e 571 Pfam PF00664 ABC transporter transmembrane region 56 287 4.4E-16 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS13005 da211de7efc03810abbe2022712a57b4 169 Pfam PF13302 Acetyltransferase (GNAT) domain 15 146 3.6E-15 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS13005 da211de7efc03810abbe2022712a57b4 169 PANTHER PTHR13256 1 158 2.2E-40 T 09-11-2016 CLOSPO_RS13005 da211de7efc03810abbe2022712a57b4 169 SUPERFAMILY SSF55729 14 155 1.67E-19 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13005 da211de7efc03810abbe2022712a57b4 169 Gene3D G3DSA:3.40.630.30 4 153 8.1E-24 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13005 da211de7efc03810abbe2022712a57b4 169 PANTHER PTHR13256:SF39 1 158 2.2E-40 T 09-11-2016 CLOSPO_RS12795 0edf7b34a60fcdedc46edd615bb63be9 362 Pfam PF04122 Putative cell wall binding repeat 2 34 122 4.1E-16 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12795 0edf7b34a60fcdedc46edd615bb63be9 362 Pfam PF04122 Putative cell wall binding repeat 2 144 230 1.4E-11 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12795 0edf7b34a60fcdedc46edd615bb63be9 362 Pfam PF04122 Putative cell wall binding repeat 2 246 346 1.3E-14 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12795 0edf7b34a60fcdedc46edd615bb63be9 362 PANTHER PTHR30032 1 260 2.9E-33 T 09-11-2016 CLOSPO_RS12795 0edf7b34a60fcdedc46edd615bb63be9 362 Gene3D G3DSA:3.40.50.720 105 141 5.5E-4 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS12795 0edf7b34a60fcdedc46edd615bb63be9 362 PANTHER PTHR30032:SF1 1 260 2.9E-33 T 09-11-2016 CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Gene3D G3DSA:3.30.1600.10 123 170 2.1E-28 T 09-11-2016 IPR026591 Sirtuin family, catalytic core small domain CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Gene3D G3DSA:3.30.1600.10 32 74 2.1E-28 T 09-11-2016 IPR026591 Sirtuin family, catalytic core small domain CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 5 244 62.762 T 09-11-2016 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Gene3D G3DSA:3.40.50.1220 177 243 2.7E-46 T 09-11-2016 IPR029035 DHS-like NAD/FAD-binding domain CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Gene3D G3DSA:3.40.50.1220 3 31 2.7E-46 T 09-11-2016 IPR029035 DHS-like NAD/FAD-binding domain CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Gene3D G3DSA:3.40.50.1220 85 122 2.7E-46 T 09-11-2016 IPR029035 DHS-like NAD/FAD-binding domain CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 Pfam PF02146 Sir2 family 21 201 3.5E-52 T 09-11-2016 IPR003000 Sirtuin family GO:0070403 CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 PANTHER PTHR11085 3 242 9.8E-86 T 09-11-2016 IPR003000 Sirtuin family GO:0070403 CLOSPO_RS14495 5cfebe46af1eae8e8965210b4c07d2ad 247 SUPERFAMILY SSF52467 3 242 2.0E-85 T 09-11-2016 IPR029035 DHS-like NAD/FAD-binding domain CLOSPO_RS17315 1429d80ec361f84c66a46502944c1251 331 Pfam PF13170 Protein of unknown function (DUF4003) 15 312 1.3E-106 T 09-11-2016 IPR025062 Protein of unknown function DUF4003 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 PANTHER PTHR30294:SF26 78 219 2.4E-42 T 09-11-2016 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 PANTHER PTHR30294:SF26 1 54 2.4E-42 T 09-11-2016 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 PANTHER PTHR30294:SF26 250 264 2.4E-42 T 09-11-2016 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 Pfam PF12679 ABC-2 family transporter protein 7 217 1.8E-10 T 09-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 PANTHER PTHR30294 78 219 2.4E-42 T 09-11-2016 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 PANTHER PTHR30294 1 54 2.4E-42 T 09-11-2016 CLOSPO_RS17595 bf4eb431d0579d69470a3af6bb719a62 264 PANTHER PTHR30294 250 264 2.4E-42 T 09-11-2016 CLOSPO_RS15440 e73d4e313861b98419e4d67c7bba96da 332 SMART SM01329 4 328 4.5E-197 T 09-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 CLOSPO_RS15440 e73d4e313861b98419e4d67c7bba96da 332 SUPERFAMILY SSF53659 1 331 5.76E-135 T 09-11-2016 CLOSPO_RS15440 e73d4e313861b98419e4d67c7bba96da 332 PANTHER PTHR11835 2 331 9.9E-203 T 09-11-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 CLOSPO_RS15440 e73d4e313861b98419e4d67c7bba96da 332 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 224 243 - T 09-11-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 CLOSPO_RS15440 e73d4e313861b98419e4d67c7bba96da 332 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 328 1.2E-115 T 09-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 CLOSPO_RS15440 e73d4e313861b98419e4d67c7bba96da 332 Gene3D G3DSA:3.40.718.10 1 332 3.4E-147 T 09-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 CLOSPO_RS16075 d7494d6a83720906327edc425cd2388c 70 Pfam PF04324 BFD-like [2Fe-2S] binding domain 16 67 2.8E-13 T 09-11-2016 IPR007419 BFD-like [2Fe-2S]-binding domain CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 PANTHER PTHR11228 7 287 1.3E-198 T 09-11-2016 CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 Gene3D G3DSA:3.20.20.70 3 288 1.8E-37 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 PANTHER PTHR11228:SF28 7 287 1.3E-198 T 09-11-2016 CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 Pfam PF13186 Iron-sulfur cluster-binding domain 219 284 3.0E-11 T 09-11-2016 IPR023885 4Fe4S-binding SPASM domain CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 Pfam PF04055 Radical SAM superfamily 9 119 3.4E-12 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 Pfam PF13394 4Fe-4S single cluster domain 12 93 6.4E-5 T 09-11-2016 CLOSPO_RS18855 1bde5e3c70c63a651fa7951c8f9594b3 292 SUPERFAMILY SSF102114 7 287 8.11E-37 T 09-11-2016 CLOSPO_RS14815 2062ef8c21a2f269898e77db3761dc2e 352 Gene3D G3DSA:3.20.20.70 319 345 4.6E-51 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS14815 2062ef8c21a2f269898e77db3761dc2e 352 Gene3D G3DSA:3.20.20.70 12 286 4.6E-51 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS14815 2062ef8c21a2f269898e77db3761dc2e 352 Pfam PF03060 Nitronate monooxygenase 13 350 2.9E-61 T 09-11-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CLOSPO_RS14815 2062ef8c21a2f269898e77db3761dc2e 352 PANTHER PTHR32332 2 352 2.5E-183 T 09-11-2016 CLOSPO_RS14815 2062ef8c21a2f269898e77db3761dc2e 352 SUPERFAMILY SSF51412 11 348 6.56E-52 T 09-11-2016 CLOSPO_RS14815 2062ef8c21a2f269898e77db3761dc2e 352 PANTHER PTHR32332:SF18 2 352 2.5E-183 T 09-11-2016 CLOSPO_RS13385 c6a0af430d20efdd484b045028ed47fb 187 SUPERFAMILY SSF53335 7 162 1.0E-18 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS13385 c6a0af430d20efdd484b045028ed47fb 187 PANTHER PTHR11727:SF14 27 132 9.4E-18 T 09-11-2016 CLOSPO_RS13385 c6a0af430d20efdd484b045028ed47fb 187 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 135 5.6E-8 T 09-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CLOSPO_RS13385 c6a0af430d20efdd484b045028ed47fb 187 Gene3D G3DSA:3.40.50.150 15 158 3.6E-19 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS13385 c6a0af430d20efdd484b045028ed47fb 187 PANTHER PTHR11727 27 132 9.4E-18 T 09-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 Pfam PF12848 ABC transporter 226 295 1.1E-12 T 09-11-2016 IPR032781 ABC-transporter extension domain CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 PANTHER PTHR19211 1 571 1.7E-227 T 09-11-2016 CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 SMART SM00382 343 513 1.5E-6 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 SMART SM00382 28 232 3.4E-4 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 Pfam PF00005 ABC transporter 335 469 8.0E-21 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 Pfam PF00005 ABC transporter 20 187 7.3E-26 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 Gene3D G3DSA:3.40.50.300 316 551 1.3E-45 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 SUPERFAMILY SSF52540 5 233 1.15E-46 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 PANTHER PTHR19211:SF45 1 571 1.7E-227 T 09-11-2016 CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 Gene3D G3DSA:3.40.50.300 5 283 8.5E-51 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 Pfam PF16326 ABC transporter C-terminal domain 561 626 1.5E-11 T 09-11-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CLOSPO_RS18840 96410bc056b2993bb02f309221770d1b 639 SUPERFAMILY SSF52540 311 524 7.27E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15910 d32cc8506de5f64df84460a27a51a8ce 451 Pfam PF01554 MatE 246 398 3.0E-13 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS15910 d32cc8506de5f64df84460a27a51a8ce 451 Pfam PF01554 MatE 23 184 4.2E-31 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS15910 d32cc8506de5f64df84460a27a51a8ce 451 PANTHER PTHR11206:SF132 1 444 2.1E-121 T 09-11-2016 CLOSPO_RS15910 d32cc8506de5f64df84460a27a51a8ce 451 PIRSF PIRSF006603 1 450 4.6E-80 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS15910 d32cc8506de5f64df84460a27a51a8ce 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 415 5.2E-52 T 09-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 CLOSPO_RS15910 d32cc8506de5f64df84460a27a51a8ce 451 PANTHER PTHR11206 1 444 2.1E-121 T 09-11-2016 CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 SUPERFAMILY SSF51735 6 246 1.5E-85 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PANTHER PTHR24322 11 140 1.4E-57 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PANTHER PTHR24322 156 188 1.4E-57 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.4E-47 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 6.4E-47 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.4E-47 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.4E-47 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.4E-47 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.4E-47 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 1.4E-66 T 09-11-2016 CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 09-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 Gene3D G3DSA:3.40.50.720 3 246 6.9E-87 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.3E-16 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.3E-16 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.3E-16 T 09-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PANTHER PTHR24322:SF328 11 140 1.4E-57 T 09-11-2016 CLOSPO_RS15860 2b28bf659e1f118b327a7ef6d0f29e15 247 PANTHER PTHR24322:SF328 156 188 1.4E-57 T 09-11-2016 CLOSPO_RS16330 56d229540ad91a574468dad8f180ee4c 407 Pfam PF07670 Nucleoside recognition 94 190 2.0E-8 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS16330 56d229540ad91a574468dad8f180ee4c 407 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 196 406 2.2E-77 T 09-11-2016 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS16330 56d229540ad91a574468dad8f180ee4c 407 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 406 1.8E-147 T 09-11-2016 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS16330 56d229540ad91a574468dad8f180ee4c 407 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 9.2E-24 T 09-11-2016 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS16330 56d229540ad91a574468dad8f180ee4c 407 PANTHER PTHR10590 1 407 9.7E-226 T 09-11-2016 IPR008276 Concentrative nucleoside transporter GO:0005337|GO:0016020|GO:1901642 Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS15205 3aa6886817f97b04dbacdb78f8f3977b 96 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 13 96 2.7E-34 T 09-11-2016 IPR012504 Sporulation protein YabP CLOSPO_RS15205 3aa6886817f97b04dbacdb78f8f3977b 96 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 15 96 6.0E-21 T 09-11-2016 IPR012504 Sporulation protein YabP CLOSPO_RS15205 3aa6886817f97b04dbacdb78f8f3977b 96 PIRSF PIRSF011576 1 96 2.4E-18 T 09-11-2016 IPR012504 Sporulation protein YabP CLOSPO_RS15205 3aa6886817f97b04dbacdb78f8f3977b 96 Pfam PF07873 YabP family 14 78 1.7E-19 T 09-11-2016 IPR022476 Sporulation protein YabP/YqfC CLOSPO_RS07370 5d87018b1cc12962e4f3bdb6e30cb9a4 44 SUPERFAMILY SSF53697 1 43 5.78E-5 T 09-11-2016 CLOSPO_RS07370 5d87018b1cc12962e4f3bdb6e30cb9a4 44 Gene3D G3DSA:3.40.50.10490 1 44 3.9E-10 T 09-11-2016 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 Gene3D G3DSA:3.30.390.50 241 325 6.1E-31 T 09-11-2016 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 241 324 5.9E-29 T 09-11-2016 IPR019491 Lipoate protein ligase, C-terminal UniPathway: UPA00537|UniPathway: UPA00537 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 Gene3D G3DSA:3.90.1550.10 1 239 1.4E-83 T 09-11-2016 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 PANTHER PTHR12561 1 325 5.0E-122 T 09-11-2016 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 44 149 1.6E-13 T 09-11-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 4 319 1.0E-101 T 09-11-2016 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 UniPathway: UPA00537|UniPathway: UPA00537 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 SUPERFAMILY SSF55681 1 238 1.99E-74 T 09-11-2016 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 SUPERFAMILY SSF82649 241 325 2.2E-26 T 09-11-2016 CLOSPO_RS16970 ace161971fb7f3eb97ea3b35e44931d6 325 PANTHER PTHR12561:SF3 1 325 5.0E-122 T 09-11-2016 CLOSPO_RS19000 1fa84c547cfe54368730b87882b881c9 214 Pfam PF01966 HD domain 68 186 6.3E-9 T 09-11-2016 IPR006674 HD domain CLOSPO_RS19000 1fa84c547cfe54368730b87882b881c9 214 Gene3D G3DSA:1.10.3210.10 57 190 2.0E-14 T 09-11-2016 IPR006674 HD domain CLOSPO_RS19000 1fa84c547cfe54368730b87882b881c9 214 SMART SM00471 63 198 5.7E-4 T 09-11-2016 IPR003607 HD/PDEase domain CLOSPO_RS19000 1fa84c547cfe54368730b87882b881c9 214 SUPERFAMILY SSF109604 55 204 1.82E-17 T 09-11-2016 CLOSPO_RS19000 1fa84c547cfe54368730b87882b881c9 214 TIGRFAM TIGR00277 HDIG: HDIG domain 66 122 3.3E-8 T 09-11-2016 IPR006675 HDIG domain CLOSPO_RS16655 e99cd2d20cdeacbac93b3f9c7ee9742f 271 SUPERFAMILY SSF161098 59 246 1.44E-26 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16655 e99cd2d20cdeacbac93b3f9c7ee9742f 271 PANTHER PTHR30465 2 266 2.2E-93 T 09-11-2016 CLOSPO_RS16655 e99cd2d20cdeacbac93b3f9c7ee9742f 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 264 6.0E-31 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16655 e99cd2d20cdeacbac93b3f9c7ee9742f 271 Gene3D G3DSA:1.10.3720.10 55 261 2.1E-26 T 09-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CLOSPO_RS16655 e99cd2d20cdeacbac93b3f9c7ee9742f 271 PANTHER PTHR30465:SF10 2 266 2.2E-93 T 09-11-2016 CLOSPO_RS12850 de458ad199ab5274a65556d040fae7b5 336 PANTHER PTHR30106:SF1 1 336 1.3E-180 T 09-11-2016 CLOSPO_RS12850 de458ad199ab5274a65556d040fae7b5 336 PANTHER PTHR30106 1 336 1.3E-180 T 09-11-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CLOSPO_RS12850 de458ad199ab5274a65556d040fae7b5 336 Pfam PF03601 Conserved hypothetical protein 698 9 315 2.5E-86 T 09-11-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CLOSPO_RS17205 8fecf37d26f0b7f1b8fad39fadf995b8 147 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 23 141 4.0E-29 T 09-11-2016 IPR010181 CGCAxxGCC motif CLOSPO_RS17205 8fecf37d26f0b7f1b8fad39fadf995b8 147 SUPERFAMILY SSF48695 5 143 2.76E-13 T 09-11-2016 IPR011031 Multihaem cytochrome CLOSPO_RS17205 8fecf37d26f0b7f1b8fad39fadf995b8 147 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 23 142 1.2E-35 T 09-11-2016 IPR010181 CGCAxxGCC motif CLOSPO_RS01995 48a587d568ce4538092b2ed2e2a44fac 189 Pfam PF01391 Collagen triple helix repeat (20 copies) 19 75 4.6E-10 T 09-11-2016 IPR008160 Collagen triple helix repeat CLOSPO_RS01995 48a587d568ce4538092b2ed2e2a44fac 189 Pfam PF01391 Collagen triple helix repeat (20 copies) 107 163 5.8E-9 T 09-11-2016 IPR008160 Collagen triple helix repeat CLOSPO_RS01995 48a587d568ce4538092b2ed2e2a44fac 189 Pfam PF01391 Collagen triple helix repeat (20 copies) 56 111 6.1E-7 T 09-11-2016 IPR008160 Collagen triple helix repeat CLOSPO_RS01995 48a587d568ce4538092b2ed2e2a44fac 189 PANTHER PTHR24023 19 163 5.7E-33 T 09-11-2016 CLOSPO_RS13610 1807658cfc7bb3a120c643d0bfd9f764 367 PANTHER PTHR34296:SF2 3 366 7.6E-135 T 09-11-2016 CLOSPO_RS13610 1807658cfc7bb3a120c643d0bfd9f764 367 PANTHER PTHR34296 3 366 7.6E-135 T 09-11-2016 CLOSPO_RS13610 1807658cfc7bb3a120c643d0bfd9f764 367 Gene3D G3DSA:3.40.50.2300 36 159 4.6E-50 T 09-11-2016 CLOSPO_RS13610 1807658cfc7bb3a120c643d0bfd9f764 367 Pfam PF02608 Basic membrane protein 45 350 3.2E-65 T 09-11-2016 IPR003760 Basic membrane lipoprotein GO:0005886 CLOSPO_RS13610 1807658cfc7bb3a120c643d0bfd9f764 367 Gene3D G3DSA:3.40.50.2300 160 323 3.4E-52 T 09-11-2016 CLOSPO_RS13610 1807658cfc7bb3a120c643d0bfd9f764 367 SUPERFAMILY SSF53822 41 290 1.02E-10 T 09-11-2016 IPR028082 Periplasmic binding protein-like I CLOSPO_RS18690 b60371fd582de8065fbcdd1eaea6fc5a 317 PANTHER PTHR30472:SF27 1 317 2.5E-182 T 09-11-2016 CLOSPO_RS18690 b60371fd582de8065fbcdd1eaea6fc5a 317 PANTHER PTHR30472 1 317 2.5E-182 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS18690 b60371fd582de8065fbcdd1eaea6fc5a 317 Pfam PF01032 FecCD transport family 10 311 1.8E-66 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS18690 b60371fd582de8065fbcdd1eaea6fc5a 317 Gene3D G3DSA:1.10.3470.10 6 313 1.2E-70 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS18690 b60371fd582de8065fbcdd1eaea6fc5a 317 SUPERFAMILY SSF81345 5 312 9.15E-67 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 SUPERFAMILY SSF52540 1 223 5.32E-76 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 Pfam PF00005 ABC transporter 21 169 7.5E-33 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 PANTHER PTHR24220:SF578 3 230 2.7E-135 T 09-11-2016 CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 PANTHER PTHR24220 3 230 2.7E-135 T 09-11-2016 CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 SMART SM00382 30 217 4.8E-11 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS14300 88155ac85ad8ae7bb81509395e14c4c5 231 Gene3D G3DSA:3.40.50.300 2 223 4.6E-71 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS12780 1a558c02e2d167c2a476e6e4c7408720 344 PIRSF PIRSF006268 2 337 2.2E-111 T 09-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 CLOSPO_RS12780 1a558c02e2d167c2a476e6e4c7408720 344 PANTHER PTHR30040:SF2 1 339 1.4E-148 T 09-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 CLOSPO_RS12780 1a558c02e2d167c2a476e6e4c7408720 344 PANTHER PTHR30040 1 339 1.4E-148 T 09-11-2016 CLOSPO_RS12780 1a558c02e2d167c2a476e6e4c7408720 344 Pfam PF02424 ApbE family 37 315 2.2E-86 T 09-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 CLOSPO_RS12780 1a558c02e2d167c2a476e6e4c7408720 344 SUPERFAMILY SSF143631 29 332 1.2E-98 T 09-11-2016 IPR003374 ApbE-like domain CLOSPO_RS18520 4498d45062251997f6e9e8a49331c1af 174 SMART SM00347 57 160 6.0E-10 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS18520 4498d45062251997f6e9e8a49331c1af 174 Pfam PF01047 MarR family 64 122 7.3E-7 T 09-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOSPO_RS18520 4498d45062251997f6e9e8a49331c1af 174 Gene3D G3DSA:1.10.10.10 53 172 1.8E-22 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18520 4498d45062251997f6e9e8a49331c1af 174 SUPERFAMILY SSF46785 62 172 2.05E-16 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18520 4498d45062251997f6e9e8a49331c1af 174 PANTHER PTHR35790:SF1 1 174 1.4E-39 T 09-11-2016 CLOSPO_RS18520 4498d45062251997f6e9e8a49331c1af 174 PANTHER PTHR35790 1 174 1.4E-39 T 09-11-2016 CLOSPO_RS15080 197507d05fda9a8613c2921368c3229b 348 PANTHER PTHR37814 1 348 5.2E-140 T 09-11-2016 CLOSPO_RS15080 197507d05fda9a8613c2921368c3229b 348 PANTHER PTHR37814:SF1 1 348 5.2E-140 T 09-11-2016 CLOSPO_RS17455 711fe0a7b3344b8b0ba4f057d695b022 114 Gene3D G3DSA:3.40.50.1820 36 109 1.8E-5 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS15950 6850c318d69b0410568d7e4a1e859dc1 109 Pfam PF12788 YmaF family 8 102 1.9E-40 T 09-11-2016 IPR024307 YmaF CLOSPO_RS14920 1316b0ccc25200a994c61c3c0c2a22b7 457 PANTHER PTHR11819:SF12 1 448 8.4E-65 T 09-11-2016 CLOSPO_RS14920 1316b0ccc25200a994c61c3c0c2a22b7 457 Pfam PF00474 Sodium:solute symporter family 31 415 1.2E-24 T 09-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS14920 1316b0ccc25200a994c61c3c0c2a22b7 457 PANTHER PTHR11819 1 448 8.4E-65 T 09-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS17410 2b5a12dfcb826c907d806ef1046bca8c 253 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 172 1.2E-12 T 09-11-2016 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CLOSPO_RS17410 2b5a12dfcb826c907d806ef1046bca8c 253 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 246 4.8E-30 T 09-11-2016 IPR013337 CRISPR-associated protein Cas5, Tneap type CLOSPO_RS17410 2b5a12dfcb826c907d806ef1046bca8c 253 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 44 3.4E-13 T 09-11-2016 IPR013422 CRISPR-associated protein Cas5, N-terminal CLOSPO_RS18275 aa25a68e976d1b1edbbcd8271d398d85 355 PANTHER PTHR30472 1 353 4.8E-234 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS18275 aa25a68e976d1b1edbbcd8271d398d85 355 Pfam PF01032 FecCD transport family 25 347 2.0E-97 T 09-11-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 CLOSPO_RS18275 aa25a68e976d1b1edbbcd8271d398d85 355 SUPERFAMILY SSF81345 8 347 1.18E-82 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS18275 aa25a68e976d1b1edbbcd8271d398d85 355 Gene3D G3DSA:1.10.3470.10 15 349 4.9E-105 T 09-11-2016 IPR029022 ABC transporter, BtuC-like CLOSPO_RS18275 aa25a68e976d1b1edbbcd8271d398d85 355 PANTHER PTHR30472:SF18 1 353 4.8E-234 T 09-11-2016 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 Pfam PF00375 Sodium:dicarboxylate symporter family 8 378 3.2E-71 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PANTHER PTHR11958:SF53 1 386 1.5E-210 T 09-11-2016 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 SUPERFAMILY SSF118215 8 378 4.58E-69 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 1.4E-7 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 1.4E-7 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PRINTS PR00173 Glutamate-aspartate symporter signature 335 355 1.4E-7 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 1.4E-7 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PRINTS PR00173 Glutamate-aspartate symporter signature 271 297 1.4E-7 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 PANTHER PTHR11958 1 386 1.5E-210 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS13530 fe55a397f347183a20bee89ed358b99a 387 Gene3D G3DSA:1.10.3860.10 3 385 1.3E-52 T 09-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 4.7E-14 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 PANTHER PTHR30055 1 189 3.1E-76 T 09-11-2016 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 SUPERFAMILY SSF46689 7 66 1.45E-16 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-8 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-8 T 09-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 SUPERFAMILY SSF48498 78 189 9.45E-26 T 09-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 PANTHER PTHR30055:SF40 1 189 3.1E-76 T 09-11-2016 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 Gene3D G3DSA:1.10.357.10 56 189 1.1E-38 T 09-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 Gene3D G3DSA:1.10.10.60 4 55 6.0E-22 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS15000 4243bc3661a44eabfc060a16d22dc802 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 183 2.1E-28 T 09-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 SUPERFAMILY SSF46894 135 235 4.25E-28 T 09-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 PANTHER PTHR26402:SF611 9 235 3.2E-150 T 09-11-2016 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 PANTHER PTHR26402 9 235 3.2E-150 T 09-11-2016 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 SUPERFAMILY SSF52172 4 138 2.99E-38 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 Pfam PF00072 Response regulator receiver domain 11 120 2.2E-26 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 SMART SM00448 9 120 4.4E-39 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 SMART SM00862 158 234 1.0E-23 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 2.8E-24 T 09-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 Gene3D G3DSA:1.10.10.10 134 235 1.3E-32 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS18260 1752d02e4cd7377ab756edc98b371869 240 Gene3D G3DSA:3.40.50.2300 6 127 4.6E-36 T 09-11-2016 CLOSPO_RS14270 fe8e2c0d7f27e1a19ec68d7500e3977f 242 PANTHER PTHR33778 5 237 1.1E-63 T 09-11-2016 CLOSPO_RS14270 fe8e2c0d7f27e1a19ec68d7500e3977f 242 Pfam PF02308 MgtC family 11 147 6.3E-39 T 09-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOSPO_RS14270 fe8e2c0d7f27e1a19ec68d7500e3977f 242 PRINTS PR01837 MgtC/SapB protein signature 74 96 4.6E-41 T 09-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOSPO_RS14270 fe8e2c0d7f27e1a19ec68d7500e3977f 242 PRINTS PR01837 MgtC/SapB protein signature 13 32 4.6E-41 T 09-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOSPO_RS14270 fe8e2c0d7f27e1a19ec68d7500e3977f 242 PRINTS PR01837 MgtC/SapB protein signature 32 50 4.6E-41 T 09-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOSPO_RS14270 fe8e2c0d7f27e1a19ec68d7500e3977f 242 PRINTS PR01837 MgtC/SapB protein signature 101 125 4.6E-41 T 09-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 PANTHER PTHR24220:SF580 5 221 3.5E-120 T 09-11-2016 CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 Pfam PF00005 ABC transporter 23 171 1.4E-33 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 Gene3D G3DSA:3.40.50.300 4 221 8.9E-64 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 SMART SM00382 32 220 1.3E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 SUPERFAMILY SSF52540 4 221 1.34E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS16275 5f6cdc5b3db1b8dadfb75c29725f322d 226 PANTHER PTHR24220 5 221 3.5E-120 T 09-11-2016 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 SUPERFAMILY SSF52540 131 247 4.25E-45 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 SUPERFAMILY SSF52540 3 94 4.25E-45 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 SUPERFAMILY SSF52540 306 507 6.48E-36 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 Pfam PF12848 ABC transporter 229 313 6.6E-24 T 09-11-2016 IPR032781 ABC-transporter extension domain CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 Gene3D G3DSA:3.40.50.300 124 278 5.0E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 Gene3D G3DSA:3.40.50.300 326 507 1.1E-35 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 Gene3D G3DSA:3.40.50.300 2 90 5.0E-47 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 Pfam PF00005 ABC transporter 20 190 2.0E-25 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 Pfam PF00005 ABC transporter 340 468 9.2E-22 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 PANTHER PTHR19211 1 514 0.0 T 09-11-2016 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 09-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 PANTHER PTHR19211:SF65 1 514 0.0 T 09-11-2016 CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 SMART SM00382 348 510 5.7E-9 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17040 989f31b6c6ef72ace183b8d2876ded46 517 SMART SM00382 28 237 2.8E-7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS12710 ad248d84807670950a9e122149b24640 483 PIRSF PIRSF006060 2 479 7.4E-92 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS12710 ad248d84807670950a9e122149b24640 483 Pfam PF13520 Amino acid permease 23 448 3.5E-47 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS12710 ad248d84807670950a9e122149b24640 483 PANTHER PTHR11785:SF342 4 480 1.8E-108 T 09-11-2016 CLOSPO_RS12710 ad248d84807670950a9e122149b24640 483 PANTHER PTHR11785 4 480 1.8E-108 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 SUPERFAMILY SSF53790 20 237 4.58E-46 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 21 222 1.5E-42 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 PANTHER PTHR10882 21 234 1.4E-37 T 09-11-2016 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 20 236 3.2E-54 T 09-11-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 PIRSF PIRSF036427 18 238 1.2E-63 T 09-11-2016 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 Gene3D G3DSA:3.40.1010.10 20 142 4.5E-32 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS18140 1e9eb4719b1f0395c7fa0e43df19d9a3 238 PANTHER PTHR10882:SF1 21 234 1.4E-37 T 09-11-2016 CLOSPO_RS13595 74d4d9364805fac91e4413f8db0249cd 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 286 1.6E-40 T 09-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CLOSPO_RS13595 74d4d9364805fac91e4413f8db0249cd 308 PANTHER PTHR32196 10 308 1.2E-137 T 09-11-2016 CLOSPO_RS13595 74d4d9364805fac91e4413f8db0249cd 308 PANTHER PTHR32196:SF40 10 308 1.2E-137 T 09-11-2016 CLOSPO_RS13920 48d61bed8eba25638b31745d3d3d2a83 248 SUPERFAMILY SSF51261 64 246 1.46E-28 T 09-11-2016 IPR011055 Duplicated hybrid motif CLOSPO_RS13920 48d61bed8eba25638b31745d3d3d2a83 248 Pfam PF01551 Peptidase family M23 143 242 2.2E-21 T 09-11-2016 IPR016047 Peptidase M23 CLOSPO_RS13920 48d61bed8eba25638b31745d3d3d2a83 248 Gene3D G3DSA:2.70.70.10 87 247 8.3E-33 T 09-11-2016 CLOSPO_RS13920 48d61bed8eba25638b31745d3d3d2a83 248 PANTHER PTHR21666:SF200 28 247 2.0E-20 T 09-11-2016 CLOSPO_RS13920 48d61bed8eba25638b31745d3d3d2a83 248 PANTHER PTHR21666 28 247 2.0E-20 T 09-11-2016 CLOSPO_RS17115 73f725a099b44f63fb944ebe775bf572 166 PANTHER PTHR33387 3 165 2.7E-70 T 09-11-2016 CLOSPO_RS17115 73f725a099b44f63fb944ebe775bf572 166 PANTHER PTHR33387:SF3 3 165 2.7E-70 T 09-11-2016 CLOSPO_RS17115 73f725a099b44f63fb944ebe775bf572 166 Pfam PF06172 Cupin superfamily (DUF985) 6 143 1.0E-44 T 09-11-2016 IPR009327 Cupin domain of unknown function DUF985 CLOSPO_RS17115 73f725a099b44f63fb944ebe775bf572 166 Gene3D G3DSA:2.60.120.10 2 165 9.3E-62 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS17115 73f725a099b44f63fb944ebe775bf572 166 SUPERFAMILY SSF51182 2 165 1.25E-58 T 09-11-2016 IPR011051 RmlC-like cupin domain CLOSPO_RS13080 b3dced8f1ebef2791ae9148fa99e1ada 285 PANTHER PTHR30622 4 284 2.6E-130 T 09-11-2016 CLOSPO_RS13080 b3dced8f1ebef2791ae9148fa99e1ada 285 PANTHER PTHR30622:SF3 4 284 2.6E-130 T 09-11-2016 CLOSPO_RS13080 b3dced8f1ebef2791ae9148fa99e1ada 285 Pfam PF02673 Bacitracin resistance protein BacA 11 270 1.4E-72 T 09-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOSPO_RS13080 b3dced8f1ebef2791ae9148fa99e1ada 285 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 6 276 17.027 T 09-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOSPO_RS13080 b3dced8f1ebef2791ae9148fa99e1ada 285 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 11 268 5.1E-71 T 09-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOSPO_RS15790 cf96e0cdb3172ada621bb515a0b94542 374 PANTHER PTHR30294 1 374 4.0E-167 T 09-11-2016 CLOSPO_RS15790 cf96e0cdb3172ada621bb515a0b94542 374 Pfam PF12698 ABC-2 family transporter protein 19 367 2.0E-34 T 09-11-2016 CLOSPO_RS15790 cf96e0cdb3172ada621bb515a0b94542 374 PANTHER PTHR30294:SF23 1 374 4.0E-167 T 09-11-2016 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 SUPERFAMILY SSF51569 1 303 1.19E-104 T 09-11-2016 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 305 8.7E-102 T 09-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 PANTHER PTHR30304 1 297 1.2E-119 T 09-11-2016 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 304 2.5E-107 T 09-11-2016 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 300 1.1E-88 T 09-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 PIRSF PIRSF001359 1 307 3.0E-100 T 09-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOSPO_RS13740 2da6a92dd3e0bf240f6d49dcccce5ab4 308 Gene3D G3DSA:3.20.20.70 1 306 6.5E-111 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS17845 750101532eb9c3513796551915e79265 125 Pfam PF03734 L,D-transpeptidase catalytic domain 16 124 3.2E-22 T 09-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 CLOSPO_RS17845 750101532eb9c3513796551915e79265 125 Gene3D G3DSA:2.40.440.10 14 125 4.0E-40 T 09-11-2016 CLOSPO_RS17845 750101532eb9c3513796551915e79265 125 SUPERFAMILY SSF141523 16 124 3.92E-37 T 09-11-2016 CLOSPO_RS17845 750101532eb9c3513796551915e79265 125 PANTHER PTHR30582 1 125 1.9E-37 T 09-11-2016 CLOSPO_RS17355 c6ac6f18b00254be976592b0254e2262 62 Pfam PF08141 Small acid-soluble spore protein H family 1 54 1.1E-16 T 09-11-2016 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CLOSPO_RS17355 c6ac6f18b00254be976592b0254e2262 62 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 56 1.3E-23 T 09-11-2016 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CLOSPO_RS17355 c6ac6f18b00254be976592b0254e2262 62 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 57 14.482 T 09-11-2016 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 Gene3D G3DSA:3.30.465.10 82 194 2.8E-12 T 09-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 PANTHER PTHR11748 3 439 5.9E-142 T 09-11-2016 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 Pfam PF08031 Berberine and berberine like 396 440 8.9E-10 T 09-11-2016 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 Gene3D G3DSA:3.30.43.10 12 80 2.9E-11 T 09-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 Pfam PF01565 FAD binding domain 27 160 2.1E-28 T 09-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 PANTHER PTHR11748:SF86 3 439 5.9E-142 T 09-11-2016 CLOSPO_RS13300 df19b904054209bc181435b8cca4c085 440 SUPERFAMILY SSF56176 19 194 2.66E-50 T 09-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 SMART SM00342 183 266 1.0E-24 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 Pfam PF12833 Helix-turn-helix domain 189 267 1.0E-19 T 09-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 Gene3D G3DSA:1.10.10.60 168 217 1.4E-7 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 PANTHER PTHR11019:SF101 1 274 2.5E-127 T 09-11-2016 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 PANTHER PTHR11019 1 274 2.5E-127 T 09-11-2016 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 Gene3D G3DSA:1.10.10.60 220 269 1.4E-17 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 SUPERFAMILY SSF46689 220 270 3.58E-14 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 1.3E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS16855 322ca3b1f64346ff166bdd7bd0841e9c 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 1.3E-6 T 09-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOSPO_RS15060 1c3d4bbeb2d873f8693adcb459c06687 124 Pfam PF12646 Domain of unknown function (DUF3783) 64 119 7.4E-17 T 09-11-2016 IPR016621 Uncharacterised conserved protein UCP014543 CLOSPO_RS15060 1c3d4bbeb2d873f8693adcb459c06687 124 PIRSF PIRSF014543 1 124 2.2E-26 T 09-11-2016 IPR016621 Uncharacterised conserved protein UCP014543 CLOSPO_RS17140 40f49f1bbf6abc3b0d3c5a5f06305b34 66 Gene3D G3DSA:1.10.260.40 7 55 4.2E-11 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17140 40f49f1bbf6abc3b0d3c5a5f06305b34 66 Pfam PF01381 Helix-turn-helix 10 56 7.1E-12 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS17140 40f49f1bbf6abc3b0d3c5a5f06305b34 66 SUPERFAMILY SSF47413 7 56 6.08E-11 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS17140 40f49f1bbf6abc3b0d3c5a5f06305b34 66 SMART SM00530 7 59 3.5E-7 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16390 0ae91dabcfaef8fece6bbb739800277e 359 Pfam PF07532 Bacterial Ig-like domain (group 4) 131 185 3.7E-10 T 09-11-2016 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CLOSPO_RS16390 0ae91dabcfaef8fece6bbb739800277e 359 SUPERFAMILY SSF48452 51 116 7.82E-8 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS16390 0ae91dabcfaef8fece6bbb739800277e 359 Gene3D G3DSA:1.25.40.10 45 112 8.3E-7 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS13915 b558e0591c938e9fc6f2f9ae33566c41 84 SUPERFAMILY SSF46689 2 49 6.36E-5 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13915 b558e0591c938e9fc6f2f9ae33566c41 84 Pfam PF12116 Stage III sporulation protein D 2 81 1.2E-44 T 09-11-2016 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CLOSPO_RS13915 b558e0591c938e9fc6f2f9ae33566c41 84 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 09-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CLOSPO_RS13915 b558e0591c938e9fc6f2f9ae33566c41 84 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 80 1.1E-48 T 09-11-2016 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CLOSPO_RS14675 db84bb2fe1090473da33eccd3bfd07ca 335 PANTHER PTHR41324:SF1 2 331 1.2E-70 T 09-11-2016 CLOSPO_RS14675 db84bb2fe1090473da33eccd3bfd07ca 335 Pfam PF09991 Predicted membrane protein (DUF2232) 20 314 5.2E-69 T 09-11-2016 IPR018710 Protein of unknown function DUF2232 CLOSPO_RS14675 db84bb2fe1090473da33eccd3bfd07ca 335 PANTHER PTHR41324 2 331 1.2E-70 T 09-11-2016 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 SUPERFAMILY SSF46785 4 88 1.63E-24 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 33 51 - T 09-11-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 PANTHER PTHR33154 4 100 2.3E-46 T 09-11-2016 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 SMART SM00418 10 88 2.7E-27 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 PANTHER PTHR33154:SF3 4 100 2.3E-46 T 09-11-2016 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 3.7E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 3.7E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 3.7E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 3.7E-20 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 1.7E-16 T 09-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOSPO_RS17210 9fdb5644dbd505eccaf9b28f9f220019 105 Gene3D G3DSA:1.10.10.10 4 93 5.5E-30 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16265 9128f9d583f3a66c4a9509d3fbb52298 159 SUPERFAMILY SSF55729 1 151 9.22E-15 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16265 9128f9d583f3a66c4a9509d3fbb52298 159 Gene3D G3DSA:3.40.630.30 1 149 3.4E-15 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS13600 9f6c2cb8f3e951f8aee80d0e3db3e5f5 367 PANTHER PTHR32196 5 362 7.5E-133 T 09-11-2016 CLOSPO_RS13600 9f6c2cb8f3e951f8aee80d0e3db3e5f5 367 Pfam PF02653 Branched-chain amino acid transport system / permease component 74 346 3.4E-36 T 09-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CLOSPO_RS13600 9f6c2cb8f3e951f8aee80d0e3db3e5f5 367 PANTHER PTHR32196:SF30 5 362 7.5E-133 T 09-11-2016 CLOSPO_RS15825 ea2a7e96811ea65ea94fe77bec58f4ff 382 PANTHER PTHR30294 1 377 8.4E-64 T 09-11-2016 CLOSPO_RS15825 ea2a7e96811ea65ea94fe77bec58f4ff 382 Gene3D G3DSA:3.40.1710.10 45 119 5.0E-7 T 09-11-2016 CLOSPO_RS15825 ea2a7e96811ea65ea94fe77bec58f4ff 382 PANTHER PTHR30294:SF21 1 377 8.4E-64 T 09-11-2016 CLOSPO_RS15825 ea2a7e96811ea65ea94fe77bec58f4ff 382 Pfam PF12698 ABC-2 family transporter protein 19 370 1.2E-47 T 09-11-2016 CLOSPO_RS12745 409d28bb3ee94639ebb4dc79df19c630 329 PANTHER PTHR40074:SF2 1 327 1.4E-127 T 09-11-2016 CLOSPO_RS12745 409d28bb3ee94639ebb4dc79df19c630 329 Pfam PF01757 Acyltransferase family 1 313 1.5E-30 T 09-11-2016 IPR002656 Acyltransferase 3 GO:0016747 CLOSPO_RS12745 409d28bb3ee94639ebb4dc79df19c630 329 PANTHER PTHR40074 1 327 1.4E-127 T 09-11-2016 CLOSPO_RS09225 238d2c21913e99dbb2c1244661267356 126 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 1 122 1.4E-18 T 09-11-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 SMART SM00257 471 515 1.4E-17 T 09-11-2016 IPR018392 LysM domain CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 Pfam PF12673 Domain of unknown function (DUF3794) 190 267 5.5E-9 T 09-11-2016 IPR024300 Domain of unknown function DUF3794 CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 Pfam PF12673 Domain of unknown function (DUF3794) 346 426 4.4E-17 T 09-11-2016 IPR024300 Domain of unknown function DUF3794 CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 Pfam PF12673 Domain of unknown function (DUF3794) 37 119 9.9E-13 T 09-11-2016 IPR024300 Domain of unknown function DUF3794 CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 PANTHER PTHR21666 425 520 5.0E-15 T 09-11-2016 CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 SUPERFAMILY SSF54106 470 515 7.98E-13 T 09-11-2016 IPR018392 LysM domain CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 Pfam PF01476 LysM domain 472 515 8.5E-16 T 09-11-2016 IPR018392 LysM domain CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 PANTHER PTHR21666:SF197 425 520 5.0E-15 T 09-11-2016 CLOSPO_RS14140 d2ad560e452535e38e19d94cc1f06d44 520 Gene3D G3DSA:3.10.350.10 469 516 3.7E-18 T 09-11-2016 IPR018392 LysM domain CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 Gene3D G3DSA:3.40.1010.10 1 111 1.6E-32 T 09-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 205 1.8E-40 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 Gene3D G3DSA:3.30.950.10 112 221 6.9E-9 T 09-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 PANTHER PTHR21091:SF9 1 179 4.8E-58 T 09-11-2016 CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 4 239 1.0E-91 T 09-11-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 PANTHER PTHR21091 1 179 4.8E-58 T 09-11-2016 CLOSPO_RS18155 6846756f2e24418a9fbc8247a031142a 243 SUPERFAMILY SSF53790 1 238 1.06E-56 T 09-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 Pfam PF03129 Anticodon binding domain 166 224 5.5E-11 T 09-11-2016 IPR004154 Anticodon-binding CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 Gene3D G3DSA:3.90.960.10 7 70 2.1E-10 T 09-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 PANTHER PTHR11451:SF31 89 224 2.4E-35 T 09-11-2016 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 PANTHER PTHR11451 89 224 2.4E-35 T 09-11-2016 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 Gene3D G3DSA:3.40.50.800 158 224 3.4E-15 T 09-11-2016 IPR004154 Anticodon-binding CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 Pfam PF04073 Aminoacyl-tRNA editing domain 3 70 5.6E-11 T 09-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 Gene3D G3DSA:3.30.930.10 90 157 9.7E-4 T 09-11-2016 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 SUPERFAMILY SSF55826 4 72 3.14E-11 T 09-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CLOSPO_RS07000 1a6c6a3f137364dad50e366e87a33088 224 SUPERFAMILY SSF52954 154 224 4.74E-17 T 09-11-2016 IPR004154 Anticodon-binding CLOSPO_RS13590 59163fbcbfb5606e4da36b9aba842c39 241 SUPERFAMILY SSF88713 36 229 4.45E-52 T 09-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOSPO_RS13590 59163fbcbfb5606e4da36b9aba842c39 241 PANTHER PTHR10587 27 234 1.1E-51 T 09-11-2016 CLOSPO_RS13590 59163fbcbfb5606e4da36b9aba842c39 241 Gene3D G3DSA:3.20.20.370 13 230 9.2E-60 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS13590 59163fbcbfb5606e4da36b9aba842c39 241 Pfam PF01522 Polysaccharide deacetylase 36 143 4.5E-30 T 09-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOSPO_RS13590 59163fbcbfb5606e4da36b9aba842c39 241 PANTHER PTHR10587:SF15 27 234 1.1E-51 T 09-11-2016 CLOSPO_RS00495 d52c8ce5b97b7cd22bab6cd911f3fff2 84 Pfam PF05228 CHASE4 domain 3 83 5.2E-8 T 09-11-2016 IPR007892 CHASE4 CLOSPO_RS12705 0805a213476b09cdbb2e5941219a16a1 491 PIRSF PIRSF006060 1 479 7.2E-89 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS12705 0805a213476b09cdbb2e5941219a16a1 491 PANTHER PTHR11785:SF342 10 490 6.2E-96 T 09-11-2016 CLOSPO_RS12705 0805a213476b09cdbb2e5941219a16a1 491 Pfam PF13520 Amino acid permease 23 432 1.3E-42 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS12705 0805a213476b09cdbb2e5941219a16a1 491 PANTHER PTHR11785 10 490 6.2E-96 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 389 1.3E-85 T 09-11-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 SUPERFAMILY SSF144010 357 395 2.35E-49 T 09-11-2016 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 SUPERFAMILY SSF144010 153 198 2.35E-49 T 09-11-2016 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 SUPERFAMILY SSF144010 237 329 2.35E-49 T 09-11-2016 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 SUPERFAMILY SSF144010 6 76 2.35E-49 T 09-11-2016 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 Gene3D G3DSA:3.30.1330.100 3 61 1.9E-56 T 09-11-2016 CLOSPO_RS16675 0634a9fcf6fc6df4bd896e62e5a428c7 396 Gene3D G3DSA:3.30.1330.100 254 395 1.9E-56 T 09-11-2016 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 Pfam PF01235 Sodium:alanine symporter family 57 440 1.6E-117 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PANTHER PTHR30330:SF3 1 464 8.2E-235 T 09-11-2016 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 7.2E-129 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PRINTS PR00175 Sodium/alanine symporter signature 182 200 3.8E-47 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PRINTS PR00175 Sodium/alanine symporter signature 210 229 3.8E-47 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PRINTS PR00175 Sodium/alanine symporter signature 352 374 3.8E-47 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PRINTS PR00175 Sodium/alanine symporter signature 93 115 3.8E-47 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PRINTS PR00175 Sodium/alanine symporter signature 305 323 3.8E-47 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PRINTS PR00175 Sodium/alanine symporter signature 411 431 3.8E-47 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS19010 9b9d17396b5db4c3c0cf32464fdaf79c 465 PANTHER PTHR30330 1 464 8.2E-235 T 09-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOSPO_RS15750 e564b7ccab3852f9e3b5acf8bf364187 338 Gene3D G3DSA:2.120.10.60 57 208 4.8E-7 T 09-11-2016 CLOSPO_RS15750 e564b7ccab3852f9e3b5acf8bf364187 338 SUPERFAMILY SSF82171 49 261 4.32E-10 T 09-11-2016 CLOSPO_RS17225 ec78ac869a538a74b90359dc0cd349bd 182 SUPERFAMILY SSF53254 15 153 1.32E-16 T 09-11-2016 IPR029033 Histidine phosphatase superfamily CLOSPO_RS17225 ec78ac869a538a74b90359dc0cd349bd 182 Gene3D G3DSA:3.40.50.1240 15 141 1.4E-11 T 09-11-2016 IPR029033 Histidine phosphatase superfamily CLOSPO_RS17225 ec78ac869a538a74b90359dc0cd349bd 182 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 16 92 1.4E-5 T 09-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 CLOSPO_RS10555 f95915dd44a20ce1a0e7591d54e39f4e 305 SUPERFAMILY SSF81296 1 63 1.05E-11 T 09-11-2016 IPR014756 Immunoglobulin E-set CLOSPO_RS10555 f95915dd44a20ce1a0e7591d54e39f4e 305 PANTHER PTHR11177:SF215 72 98 3.4E-66 T 09-11-2016 CLOSPO_RS10555 f95915dd44a20ce1a0e7591d54e39f4e 305 PANTHER PTHR11177:SF215 194 305 3.4E-66 T 09-11-2016 CLOSPO_RS10555 f95915dd44a20ce1a0e7591d54e39f4e 305 PANTHER PTHR11177 72 98 3.4E-66 T 09-11-2016 CLOSPO_RS10555 f95915dd44a20ce1a0e7591d54e39f4e 305 PANTHER PTHR11177 194 305 3.4E-66 T 09-11-2016 CLOSPO_RS10555 f95915dd44a20ce1a0e7591d54e39f4e 305 Gene3D G3DSA:2.60.40.10 1 63 8.5E-15 T 09-11-2016 IPR013783 Immunoglobulin-like fold CLOSPO_RS14440 4d9c2adbdaf537f8fb64b436389eadd7 304 PANTHER PTHR21600:SF3 5 259 9.8E-83 T 09-11-2016 CLOSPO_RS14440 4d9c2adbdaf537f8fb64b436389eadd7 304 PANTHER PTHR21600 5 259 9.8E-83 T 09-11-2016 CLOSPO_RS14440 4d9c2adbdaf537f8fb64b436389eadd7 304 Pfam PF04468 PSP1 C-terminal conserved region 61 146 2.5E-34 T 09-11-2016 IPR007557 PSP1, C-terminal CLOSPO_RS14160 65c60729a007efad603b370d5479def8 375 SUPERFAMILY SSF53756 9 372 8.72E-80 T 09-11-2016 CLOSPO_RS14160 65c60729a007efad603b370d5479def8 375 PANTHER PTHR12526 1 372 1.7E-108 T 09-11-2016 CLOSPO_RS14160 65c60729a007efad603b370d5479def8 375 PANTHER PTHR12526:SF399 1 372 1.7E-108 T 09-11-2016 CLOSPO_RS14160 65c60729a007efad603b370d5479def8 375 Pfam PF13439 Glycosyltransferase Family 4 17 168 7.1E-10 T 09-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain CLOSPO_RS14160 65c60729a007efad603b370d5479def8 375 Pfam PF00534 Glycosyl transferases group 1 194 349 2.9E-37 T 09-11-2016 IPR001296 Glycosyl transferase, family 1 CLOSPO_RS14160 65c60729a007efad603b370d5479def8 375 Gene3D G3DSA:3.40.50.2000 155 349 4.4E-27 T 09-11-2016 CLOSPO_RS02780 3a3160201795c185536c37a42e11b04e 134 SUPERFAMILY SSF81606 11 118 5.49E-5 T 09-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CLOSPO_RS02780 3a3160201795c185536c37a42e11b04e 134 PANTHER PTHR21021 15 134 8.8E-22 T 09-11-2016 CLOSPO_RS02780 3a3160201795c185536c37a42e11b04e 134 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 26 132 7.1E-15 T 09-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CLOSPO_RS02780 3a3160201795c185536c37a42e11b04e 134 PANTHER PTHR21021:SF22 15 134 8.8E-22 T 09-11-2016 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 230 339 4.4E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PANTHER PTHR24423:SF539 96 341 3.5E-82 T 09-11-2016 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 SMART SM00387 229 344 4.4E-26 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PANTHER PTHR24423:SF539 4 20 3.5E-82 T 09-11-2016 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 1.5E-11 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 SUPERFAMILY SSF55874 188 340 3.54E-32 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 Gene3D G3DSA:3.30.565.10 192 339 6.7E-33 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PANTHER PTHR24423 4 20 3.5E-82 T 09-11-2016 CLOSPO_RS13265 90e3bc5ba396e5ef1b6becdaf74624bf 349 PANTHER PTHR24423 96 341 3.5E-82 T 09-11-2016 CLOSPO_RS14080 38c60c7d46360e0d21c96e7e3b009adf 326 PANTHER PTHR11933 1 230 2.4E-144 T 09-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 CLOSPO_RS14080 38c60c7d46360e0d21c96e7e3b009adf 326 PANTHER PTHR11933:SF6 1 230 2.4E-144 T 09-11-2016 CLOSPO_RS14080 38c60c7d46360e0d21c96e7e3b009adf 326 SUPERFAMILY SSF52402 2 227 2.65E-32 T 09-11-2016 CLOSPO_RS14080 38c60c7d46360e0d21c96e7e3b009adf 326 Pfam PF05670 Domain of unknown function (DUF814) 226 305 3.8E-6 T 09-11-2016 IPR008532 Domain of unknown function DUF814 CLOSPO_RS14080 38c60c7d46360e0d21c96e7e3b009adf 326 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 3 140 1.4E-11 T 09-11-2016 IPR020536 Thil, AANH domain GO:0004810 UniPathway: UPA00060 CLOSPO_RS14080 38c60c7d46360e0d21c96e7e3b009adf 326 Gene3D G3DSA:3.40.50.620 2 187 4.3E-30 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS13415 e4d7b8f9ae97155e27cca2ea7dc5c2bd 335 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 215 320 6.6E-16 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13415 e4d7b8f9ae97155e27cca2ea7dc5c2bd 335 SUPERFAMILY SSF55874 174 321 2.36E-30 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13415 e4d7b8f9ae97155e27cca2ea7dc5c2bd 335 PANTHER PTHR24423 1 321 1.6E-45 T 09-11-2016 CLOSPO_RS13415 e4d7b8f9ae97155e27cca2ea7dc5c2bd 335 Gene3D G3DSA:3.30.565.10 145 321 2.8E-30 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13415 e4d7b8f9ae97155e27cca2ea7dc5c2bd 335 PANTHER PTHR24423:SF557 1 321 1.6E-45 T 09-11-2016 CLOSPO_RS13415 e4d7b8f9ae97155e27cca2ea7dc5c2bd 335 SMART SM00387 214 325 1.5E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS15745 7683ef8995a507a87b787e6b02ab0e4a 334 PANTHER PTHR40446:SF1 1 334 9.4E-96 T 09-11-2016 CLOSPO_RS15745 7683ef8995a507a87b787e6b02ab0e4a 334 Pfam PF09992 Phosphodiester glycosidase 149 332 1.5E-48 T 09-11-2016 IPR018711 Phosphodiester glycosidase CLOSPO_RS15745 7683ef8995a507a87b787e6b02ab0e4a 334 PANTHER PTHR40446 1 334 9.4E-96 T 09-11-2016 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 PANTHER PTHR11404:SF6 7 207 4.9E-56 T 09-11-2016 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 PIRSF PIRSF000349 3 195 1.3E-44 T 09-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 188 9.4E-24 T 09-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 SUPERFAMILY SSF54719 88 192 2.88E-30 T 09-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 PANTHER PTHR11404 7 207 4.9E-56 T 09-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 Gene3D G3DSA:1.10.287.990 23 82 8.8E-4 T 09-11-2016 CLOSPO_RS15960 2e007ab6a192c99c786e65336444a196 221 SUPERFAMILY SSF46609 5 82 1.96E-10 T 09-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 CLOSPO_RS18210 7fce8a853a001239c62c133e1aa40310 340 PANTHER PTHR10192 91 317 9.0E-101 T 09-11-2016 CLOSPO_RS18210 7fce8a853a001239c62c133e1aa40310 340 SMART SM00852 173 305 1.7E-22 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS18210 7fce8a853a001239c62c133e1aa40310 340 SUPERFAMILY SSF53218 169 337 6.54E-34 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS18210 7fce8a853a001239c62c133e1aa40310 340 Gene3D G3DSA:3.40.980.10 161 303 3.4E-33 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS18210 7fce8a853a001239c62c133e1aa40310 340 PANTHER PTHR10192:SF13 91 317 9.0E-101 T 09-11-2016 CLOSPO_RS18210 7fce8a853a001239c62c133e1aa40310 340 Pfam PF00994 Probable molybdopterin binding domain 174 302 1.8E-19 T 09-11-2016 IPR001453 MoaB/Mog domain CLOSPO_RS16130 0338883f9582f85d8c2fcc26994426d4 126 SMART SM00345 15 74 1.7E-16 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS16130 0338883f9582f85d8c2fcc26994426d4 126 PANTHER PTHR38445:SF2 1 122 2.6E-24 T 09-11-2016 CLOSPO_RS16130 0338883f9582f85d8c2fcc26994426d4 126 SUPERFAMILY SSF46785 4 82 2.04E-20 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16130 0338883f9582f85d8c2fcc26994426d4 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.6E-15 T 09-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOSPO_RS16130 0338883f9582f85d8c2fcc26994426d4 126 Gene3D G3DSA:1.10.10.10 2 75 5.4E-25 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16130 0338883f9582f85d8c2fcc26994426d4 126 PANTHER PTHR38445 1 122 2.6E-24 T 09-11-2016 CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 PANTHER PTHR10108:SF330 193 243 1.4E-52 T 09-11-2016 CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 SUPERFAMILY SSF53335 54 245 2.62E-30 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 Pfam PF08241 Methyltransferase domain 66 162 3.3E-19 T 09-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 PANTHER PTHR10108 54 172 1.4E-52 T 09-11-2016 CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 PANTHER PTHR10108 193 243 1.4E-52 T 09-11-2016 CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 Gene3D G3DSA:3.40.50.150 49 235 2.9E-31 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS17095 ea80831cf88ef68771a58e8bf97637c6 257 PANTHER PTHR10108:SF330 54 172 1.4E-52 T 09-11-2016 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 SUPERFAMILY SSF53067 1 128 4.75E-57 T 09-11-2016 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 Pfam PF00871 Acetokinase family 2 164 3.9E-42 T 09-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 Hamap MF_00542 Probable butyrate kinase [buk]. 1 164 86.507 T 09-11-2016 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 PANTHER PTHR21060 1 164 7.8E-100 T 09-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 Gene3D G3DSA:3.30.420.40 135 163 3.4E-9 T 09-11-2016 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 PANTHER PTHR21060:SF3 1 164 7.8E-100 T 09-11-2016 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 134 151 - T 09-11-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 Gene3D G3DSA:3.30.420.40 1 134 8.5E-68 T 09-11-2016 CLOSPO_RS07290 36081f987a012e1714226b7351e91a9b 164 SUPERFAMILY SSF53067 128 161 9.06E-7 T 09-11-2016 CLOSPO_RS15865 6f8453996a5115624ad8748c202dbbfd 316 PANTHER PTHR26402 2 121 1.1E-25 T 09-11-2016 CLOSPO_RS15865 6f8453996a5115624ad8748c202dbbfd 316 SMART SM00448 2 115 8.5E-18 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15865 6f8453996a5115624ad8748c202dbbfd 316 SUPERFAMILY SSF52172 3 127 9.53E-25 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS15865 6f8453996a5115624ad8748c202dbbfd 316 Pfam PF00072 Response regulator receiver domain 4 115 1.6E-20 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15865 6f8453996a5115624ad8748c202dbbfd 316 PANTHER PTHR26402:SF151 2 121 1.1E-25 T 09-11-2016 CLOSPO_RS15865 6f8453996a5115624ad8748c202dbbfd 316 Gene3D G3DSA:3.40.50.2300 3 141 3.0E-25 T 09-11-2016 CLOSPO_RS13075 180361e82901f4b8d8c253428c09e92b 248 Pfam PF00005 ABC transporter 22 170 2.8E-34 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS13075 180361e82901f4b8d8c253428c09e92b 248 SMART SM00382 31 219 2.2E-12 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS13075 180361e82901f4b8d8c253428c09e92b 248 Gene3D G3DSA:3.40.50.300 2 223 1.3E-66 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13075 180361e82901f4b8d8c253428c09e92b 248 PANTHER PTHR24220:SF494 5 241 3.3E-151 T 09-11-2016 CLOSPO_RS13075 180361e82901f4b8d8c253428c09e92b 248 SUPERFAMILY SSF52540 3 224 2.54E-65 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13075 180361e82901f4b8d8c253428c09e92b 248 PANTHER PTHR24220 5 241 3.3E-151 T 09-11-2016 CLOSPO_RS18435 9d79945e51eab9aafe7f30b3667d3264 273 SUPERFAMILY SSF47781 187 255 8.89E-11 T 09-11-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 CLOSPO_RS18435 9d79945e51eab9aafe7f30b3667d3264 273 Pfam PF12836 Helix-hairpin-helix motif 191 250 2.6E-10 T 09-11-2016 CLOSPO_RS18435 9d79945e51eab9aafe7f30b3667d3264 273 PANTHER PTHR21180:SF32 1 271 2.2E-24 T 09-11-2016 CLOSPO_RS18435 9d79945e51eab9aafe7f30b3667d3264 273 Gene3D G3DSA:1.10.150.280 169 255 6.1E-8 T 09-11-2016 CLOSPO_RS18435 9d79945e51eab9aafe7f30b3667d3264 273 PANTHER PTHR21180 1 271 2.2E-24 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 PANTHER PTHR20852:SF7 3 126 1.4E-63 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 PANTHER PTHR20852:SF7 147 239 1.4E-63 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 PANTHER PTHR20852:SF7 255 434 1.4E-63 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 PANTHER PTHR20852 3 126 1.4E-63 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 PANTHER PTHR20852 147 239 1.4E-63 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 Gene3D G3DSA:3.30.590.10 130 532 6.1E-74 T 09-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 SMART SM01230 150 429 6.0E-41 T 09-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 PANTHER PTHR20852 255 434 1.4E-63 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 Pfam PF00120 Glutamine synthetase, catalytic domain 168 451 1.1E-37 T 09-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 SUPERFAMILY SSF55931 465 533 1.37E-61 T 09-11-2016 CLOSPO_RS15045 b61defca60457f194b0842dd37c1c0dd 632 SUPERFAMILY SSF55931 127 438 1.37E-61 T 09-11-2016 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 Gene3D G3DSA:3.65.10.10 21 220 7.7E-57 T 09-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.2E-168 T 09-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 SUPERFAMILY SSF55205 1 417 7.03E-134 T 09-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 Gene3D G3DSA:3.65.10.10 221 416 1.3E-62 T 09-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.238 T 09-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 PANTHER PTHR21090 1 418 3.6E-272 T 09-11-2016 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 PANTHER PTHR21090:SF19 1 418 3.6E-272 T 09-11-2016 CLOSPO_RS13930 c9c330009e3e0e6c1383fb4c3cdefefa 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 6.5E-102 T 09-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOSPO_RS15885 daff9fe1389cc09ae75c3411e288aff7 194 SMART SM00471 20 154 7.1E-9 T 09-11-2016 IPR003607 HD/PDEase domain CLOSPO_RS15885 daff9fe1389cc09ae75c3411e288aff7 194 TIGRFAM TIGR00277 HDIG: HDIG domain 24 114 3.6E-9 T 09-11-2016 IPR006675 HDIG domain CLOSPO_RS15885 daff9fe1389cc09ae75c3411e288aff7 194 SUPERFAMILY SSF109604 22 182 1.86E-34 T 09-11-2016 CLOSPO_RS15885 daff9fe1389cc09ae75c3411e288aff7 194 Gene3D G3DSA:1.10.3210.10 20 178 2.6E-21 T 09-11-2016 IPR006674 HD domain CLOSPO_RS15885 daff9fe1389cc09ae75c3411e288aff7 194 Pfam PF01966 HD domain 26 144 1.1E-16 T 09-11-2016 IPR006674 HD domain CLOSPO_RS17925 a4fda1268dd4a1a86814d30e5beb0232 182 PANTHER PTHR34295:SF2 1 182 1.2E-73 T 09-11-2016 CLOSPO_RS17925 a4fda1268dd4a1a86814d30e5beb0232 182 Pfam PF02632 BioY family 32 173 2.5E-40 T 09-11-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CLOSPO_RS17925 a4fda1268dd4a1a86814d30e5beb0232 182 PANTHER PTHR34295 1 182 1.2E-73 T 09-11-2016 CLOSPO_RS17925 a4fda1268dd4a1a86814d30e5beb0232 182 PIRSF PIRSF016661 1 181 1.8E-48 T 09-11-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CLOSPO_RS03445 5233e39149c5d67edb1f41999c7b849e 85 Gene3D G3DSA:3.40.50.150 13 85 8.5E-14 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS03445 5233e39149c5d67edb1f41999c7b849e 85 SUPERFAMILY SSF53335 13 85 3.51E-14 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS03445 5233e39149c5d67edb1f41999c7b849e 85 Pfam PF13649 Methyltransferase domain 12 84 3.0E-9 T 09-11-2016 CLOSPO_RS18635 ac2661480c1d6f550e30a08c031bf7d5 234 Gene3D G3DSA:3.30.240.20 178 232 1.4E-20 T 09-11-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CLOSPO_RS18635 ac2661480c1d6f550e30a08c031bf7d5 234 Pfam PF04239 Protein of unknown function (DUF421) 99 166 2.3E-16 T 09-11-2016 IPR007353 Protein of unknown function DUF421 CLOSPO_RS18635 ac2661480c1d6f550e30a08c031bf7d5 234 Pfam PF04239 Protein of unknown function (DUF421) 176 231 2.1E-12 T 09-11-2016 IPR007353 Protein of unknown function DUF421 CLOSPO_RS18635 ac2661480c1d6f550e30a08c031bf7d5 234 Gene3D G3DSA:3.30.240.20 96 161 1.9E-18 T 09-11-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CLOSPO_RS18635 ac2661480c1d6f550e30a08c031bf7d5 234 PANTHER PTHR34582 2 234 2.9E-45 T 09-11-2016 CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 SUPERFAMILY SSF53335 3 331 6.66E-80 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 Pfam PF02353 Mycolic acid cyclopropane synthetase 105 373 3.0E-98 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 PANTHER PTHR10108:SF743 309 392 1.1E-142 T 09-11-2016 CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 PANTHER PTHR10108:SF743 38 292 1.1E-142 T 09-11-2016 CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 Gene3D G3DSA:3.40.50.150 103 377 6.8E-94 T 09-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 PANTHER PTHR10108 309 392 1.1E-142 T 09-11-2016 CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 PIRSF PIRSF003085 2 392 4.0E-124 T 09-11-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CLOSPO_RS16455 8b70d2e2fc7ff0604cf9b2cdc70591e5 392 PANTHER PTHR10108 38 292 1.1E-142 T 09-11-2016 CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 SUPERFAMILY SSF140683 1 66 2.48E-6 T 09-11-2016 CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 Gene3D G3DSA:1.20.120.520 73 232 4.0E-30 T 09-11-2016 CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 Pfam PF04405 Domain of Unknown function (DUF542) 8 60 5.9E-19 T 09-11-2016 IPR019903 Repair of iron centres family CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 Pfam PF01814 Hemerythrin HHE cation binding domain 87 232 3.7E-21 T 09-11-2016 IPR012312 Haemerythrin-like CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 PANTHER PTHR36438 2 231 3.1E-97 T 09-11-2016 CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 PANTHER PTHR36438:SF1 2 231 3.1E-97 T 09-11-2016 CLOSPO_RS16750 b5f6ab13b0253e70ecd8dd775877ed9b 232 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 231 1.3E-74 T 09-11-2016 IPR019903 Repair of iron centres family CLOSPO_RS18220 834dc6a499b1117fa57f5d393fe773ef 258 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 133 231 4.1E-10 T 09-11-2016 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CLOSPO_RS18220 834dc6a499b1117fa57f5d393fe773ef 258 Gene3D G3DSA:2.30.30.330 121 252 1.4E-16 T 09-11-2016 CLOSPO_RS18220 834dc6a499b1117fa57f5d393fe773ef 258 SUPERFAMILY SSF54001 121 252 4.25E-21 T 09-11-2016 CLOSPO_RS18515 23b0bdc644876d32dd1987038e8e4eae 192 Gene3D G3DSA:3.50.30.50 33 191 4.3E-28 T 09-11-2016 CLOSPO_RS18515 23b0bdc644876d32dd1987038e8e4eae 192 Pfam PF04199 Putative cyclase 3 130 1.5E-10 T 09-11-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 CLOSPO_RS18515 23b0bdc644876d32dd1987038e8e4eae 192 SUPERFAMILY SSF102198 26 191 6.41E-32 T 09-11-2016 CLOSPO_RS15895 2db64d0e37f8ef3c840e849b79567909 264 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 150 258 3.5E-21 T 09-11-2016 IPR018745 Domain of unknown function DUF2294 CLOSPO_RS15895 2db64d0e37f8ef3c840e849b79567909 264 PANTHER PTHR26402 11 128 5.1E-32 T 09-11-2016 CLOSPO_RS15895 2db64d0e37f8ef3c840e849b79567909 264 SUPERFAMILY SSF52172 8 134 6.97E-33 T 09-11-2016 IPR011006 CheY-like superfamily CLOSPO_RS15895 2db64d0e37f8ef3c840e849b79567909 264 Gene3D G3DSA:3.40.50.2300 8 134 9.1E-34 T 09-11-2016 CLOSPO_RS15895 2db64d0e37f8ef3c840e849b79567909 264 Pfam PF00072 Response regulator receiver domain 13 123 8.0E-23 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS15895 2db64d0e37f8ef3c840e849b79567909 264 SMART SM00448 11 122 4.3E-26 T 09-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 140 174 1.1E-11 T 09-11-2016 IPR001451 Hexapeptide repeat CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 PANTHER PTHR23416 1 193 1.1E-70 T 09-11-2016 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 PANTHER PTHR23416:SF58 1 193 1.1E-70 T 09-11-2016 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 SMART SM01266 4 58 7.5E-20 T 09-11-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 Pfam PF12464 Maltose acetyltransferase 6 55 1.1E-14 T 09-11-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 Gene3D G3DSA:2.160.10.10 2 192 1.6E-59 T 09-11-2016 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 148 176 - T 09-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 CLOSPO_RS18045 eba05f4ecd4ee42c4acd8f545242de4e 194 SUPERFAMILY SSF51161 2 193 2.63E-50 T 09-11-2016 IPR011004 Trimeric LpxA-like CLOSPO_RS17600 0e984ed3de694aa50c569cadc4f2783e 308 SUPERFAMILY SSF52540 6 230 1.6E-55 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17600 0e984ed3de694aa50c569cadc4f2783e 308 SMART SM00382 32 218 1.4E-7 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS17600 0e984ed3de694aa50c569cadc4f2783e 308 PANTHER PTHR24220 8 241 8.4E-127 T 09-11-2016 CLOSPO_RS17600 0e984ed3de694aa50c569cadc4f2783e 308 PANTHER PTHR24220:SF428 8 241 8.4E-127 T 09-11-2016 CLOSPO_RS17600 0e984ed3de694aa50c569cadc4f2783e 308 Pfam PF00005 ABC transporter 23 167 2.8E-25 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS17600 0e984ed3de694aa50c569cadc4f2783e 308 Gene3D G3DSA:3.40.50.300 5 236 2.7E-63 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 Gene3D G3DSA:3.40.50.1470 1 184 5.5E-75 T 09-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 Pfam PF01195 Peptidyl-tRNA hydrolase 3 182 6.0E-60 T 09-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 SUPERFAMILY SSF53178 1 183 6.15E-67 T 09-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 183 1.5E-63 T 09-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 09-11-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 176 35.795 T 09-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 09-11-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS15165 15c9367bbf8673acc9fac771728e9a9b 189 PANTHER PTHR17224 1 186 1.4E-81 T 09-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOSPO_RS18325 253c9c3c1d4fb8a30212a72675ed6398 66 Pfam PF12663 Protein of unknown function (DUF3788) 3 58 3.1E-11 T 09-11-2016 IPR024265 Protein of unknown function DUF3788 CLOSPO_RS14110 b850a35ad55a1329680f7c4b24277c22 486 PANTHER PTHR22550:SF7 8 485 2.7E-177 T 09-11-2016 CLOSPO_RS14110 b850a35ad55a1329680f7c4b24277c22 486 PANTHER PTHR22550 8 485 2.7E-177 T 09-11-2016 CLOSPO_RS14110 b850a35ad55a1329680f7c4b24277c22 486 PIRSF PIRSF005690 5 486 8.1E-181 T 09-11-2016 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CLOSPO_RS14110 b850a35ad55a1329680f7c4b24277c22 486 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 18 475 2.7E-190 T 09-11-2016 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CLOSPO_RS16280 fb5673297ad4bb6a84dee1309438ed2d 154 SUPERFAMILY SSF55729 1 145 6.08E-27 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16280 fb5673297ad4bb6a84dee1309438ed2d 154 PANTHER PTHR23091 1 144 4.2E-23 T 09-11-2016 CLOSPO_RS16280 fb5673297ad4bb6a84dee1309438ed2d 154 Gene3D G3DSA:3.40.630.30 1 145 2.3E-28 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16280 fb5673297ad4bb6a84dee1309438ed2d 154 Pfam PF00583 Acetyltransferase (GNAT) family 60 144 2.3E-16 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS16940 27d0e338c1072f779314d4be3d01110a 470 Pfam PF14199 Domain of unknown function (DUF4317) 1 466 9.8E-157 T 09-11-2016 IPR025466 Protein of unknown function DUF4317 CLOSPO_RS15135 94300cd7e0bd8e213ce3ffee5d90e2a9 95 Gene3D G3DSA:3.30.1120.40 1 83 5.2E-41 T 09-11-2016 IPR007170 Stage V sporulation protein G GO:0030435 CLOSPO_RS15135 94300cd7e0bd8e213ce3ffee5d90e2a9 95 Pfam PF04026 SpoVG 1 81 1.1E-39 T 09-11-2016 IPR007170 Stage V sporulation protein G GO:0030435 CLOSPO_RS15135 94300cd7e0bd8e213ce3ffee5d90e2a9 95 PANTHER PTHR38429 2 95 8.3E-52 T 09-11-2016 CLOSPO_RS15135 94300cd7e0bd8e213ce3ffee5d90e2a9 95 SUPERFAMILY SSF160537 1 85 9.55E-36 T 09-11-2016 IPR007170 Stage V sporulation protein G GO:0030435 CLOSPO_RS15135 94300cd7e0bd8e213ce3ffee5d90e2a9 95 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 93 28.93 T 09-11-2016 IPR007170 Stage V sporulation protein G GO:0030435 CLOSPO_RS13705 62de20f3c196f641cbb939ca610e49dc 294 SMART SM00046 3 130 0.0024 T 09-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CLOSPO_RS13705 62de20f3c196f641cbb939ca610e49dc 294 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 289 9.7E-57 T 09-11-2016 IPR005218 Diacylglycerol/lipid kinase CLOSPO_RS13705 62de20f3c196f641cbb939ca610e49dc 294 PANTHER PTHR12358 3 291 4.2E-53 T 09-11-2016 CLOSPO_RS13705 62de20f3c196f641cbb939ca610e49dc 294 SUPERFAMILY SSF111331 1 290 1.5E-71 T 09-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain CLOSPO_RS13705 62de20f3c196f641cbb939ca610e49dc 294 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 126 1.0E-28 T 09-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CLOSPO_RS15590 731a077be39f54c6b0d8b17e637875c9 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 255 1.6E-102 T 09-11-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOSPO_RS15590 731a077be39f54c6b0d8b17e637875c9 266 SUPERFAMILY SSF53613 1 259 1.18E-85 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS15590 731a077be39f54c6b0d8b17e637875c9 266 PANTHER PTHR20858:SF17 1 259 7.5E-128 T 09-11-2016 CLOSPO_RS15590 731a077be39f54c6b0d8b17e637875c9 266 Pfam PF08543 Phosphomethylpyrimidine kinase 11 252 3.2E-98 T 09-11-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 CLOSPO_RS15590 731a077be39f54c6b0d8b17e637875c9 266 PANTHER PTHR20858 1 259 7.5E-128 T 09-11-2016 CLOSPO_RS15590 731a077be39f54c6b0d8b17e637875c9 266 Gene3D G3DSA:3.40.1190.20 1 255 2.4E-103 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887:SF340 1009 1226 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887 16 150 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887 191 346 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887:SF340 16 150 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887:SF340 191 346 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887 1009 1226 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 SUPERFAMILY SSF52540 259 332 4.94E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 SUPERFAMILY SSF52540 437 465 4.94E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 SUPERFAMILY SSF52540 921 1195 4.94E-43 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 Pfam PF13087 AAA domain 1011 1194 4.1E-17 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 Gene3D G3DSA:3.40.50.300 1039 1198 1.8E-7 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 Gene3D G3DSA:3.40.50.300 944 1038 5.1E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 Gene3D G3DSA:3.40.50.300 230 374 5.1E-39 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 Pfam PF13245 Part of AAA domain 276 324 1.5E-9 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887:SF340 802 986 1.4E-89 T 09-11-2016 CLOSPO_RS14220 1d41ab51c1281f6a6db33460697612a8 1350 PANTHER PTHR10887 802 986 1.4E-89 T 09-11-2016 CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 PANTHER PTHR12725:SF57 1 229 6.6E-49 T 09-11-2016 CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 SUPERFAMILY SSF56784 2 228 6.94E-46 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 79 194 1.0E-16 T 09-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 4.9E-29 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 199 2.6E-8 T 09-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 Gene3D G3DSA:3.40.50.1000 93 228 8.3E-42 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 PANTHER PTHR12725 1 229 6.6E-49 T 09-11-2016 CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 227 1.9E-67 T 09-11-2016 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CLOSPO_RS18560 1a71b1c6074c2dd28d4b9871a18f011d 229 Gene3D G3DSA:1.10.150.240 16 92 1.8E-20 T 09-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 CLOSPO_RS03210 1b88640ca124755c02af4a8b9065410d 96 Pfam PF00580 UvrD/REP helicase N-terminal domain 1 88 3.0E-15 T 09-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CLOSPO_RS03210 1b88640ca124755c02af4a8b9065410d 96 PANTHER PTHR11070 1 96 2.1E-33 T 09-11-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 CLOSPO_RS03210 1b88640ca124755c02af4a8b9065410d 96 PANTHER PTHR11070:SF14 1 96 2.1E-33 T 09-11-2016 CLOSPO_RS03210 1b88640ca124755c02af4a8b9065410d 96 SUPERFAMILY SSF52540 10 93 6.2E-10 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS03210 1b88640ca124755c02af4a8b9065410d 96 Gene3D G3DSA:3.40.50.300 19 91 4.1E-10 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14000 a8c12de70c352757e9c0263213683f99 209 PANTHER PTHR10285 8 198 1.1E-98 T 09-11-2016 CLOSPO_RS14000 a8c12de70c352757e9c0263213683f99 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 5.4E-90 T 09-11-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 CLOSPO_RS14000 a8c12de70c352757e9c0263213683f99 209 Pfam PF14681 Uracil phosphoribosyltransferase 8 208 7.7E-75 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS14000 a8c12de70c352757e9c0263213683f99 209 SUPERFAMILY SSF53271 4 207 2.62E-71 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS14000 a8c12de70c352757e9c0263213683f99 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.426 T 09-11-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 CLOSPO_RS14000 a8c12de70c352757e9c0263213683f99 209 Gene3D G3DSA:3.40.50.2020 5 209 6.9E-83 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS16985 155b00bf45f01342b245edf6300ab26c 293 SUPERFAMILY SSF103481 39 137 8.76E-14 T 09-11-2016 CLOSPO_RS16985 155b00bf45f01342b245edf6300ab26c 293 SUPERFAMILY SSF103481 186 279 4.97E-13 T 09-11-2016 CLOSPO_RS16985 155b00bf45f01342b245edf6300ab26c 293 PANTHER PTHR22911 9 288 5.5E-47 T 09-11-2016 CLOSPO_RS16985 155b00bf45f01342b245edf6300ab26c 293 Pfam PF00892 EamA-like transporter family 147 279 1.9E-21 T 09-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 CLOSPO_RS16985 155b00bf45f01342b245edf6300ab26c 293 Pfam PF00892 EamA-like transporter family 8 134 3.5E-15 T 09-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 CLOSPO_RS17945 e69a1f0306721f2e9f2c2381b13d5feb 185 PANTHER PTHR34848 1 185 2.3E-72 T 09-11-2016 CLOSPO_RS17945 e69a1f0306721f2e9f2c2381b13d5feb 185 Gene3D G3DSA:3.40.50.300 7 185 5.4E-59 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17945 e69a1f0306721f2e9f2c2381b13d5feb 185 SUPERFAMILY SSF52540 7 185 1.87E-50 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS17945 e69a1f0306721f2e9f2c2381b13d5feb 185 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 8 184 1.8E-58 T 09-11-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 CLOSPO_RS17945 e69a1f0306721f2e9f2c2381b13d5feb 185 PIRSF PIRSF006135 6 185 3.7E-57 T 09-11-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 CLOSPO_RS14735 d709136245caba4c3f22532a4f6b5ba3 124 Gene3D G3DSA:3.40.50.720 7 123 2.6E-26 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14735 d709136245caba4c3f22532a4f6b5ba3 124 SMART SM00881 6 95 6.4E-4 T 09-11-2016 IPR003781 CoA-binding GO:0048037 CLOSPO_RS14735 d709136245caba4c3f22532a4f6b5ba3 124 SUPERFAMILY SSF51735 6 121 1.14E-24 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14735 d709136245caba4c3f22532a4f6b5ba3 124 Pfam PF13380 CoA binding domain 10 120 1.2E-22 T 09-11-2016 IPR003781 CoA-binding GO:0048037 CLOSPO_RS14735 d709136245caba4c3f22532a4f6b5ba3 124 PANTHER PTHR33303 6 124 1.1E-27 T 09-11-2016 CLOSPO_RS14090 61abdb8167fb61c4360eaff8ed28c1d8 413 Gene3D G3DSA:3.40.50.2000 173 350 9.1E-26 T 09-11-2016 CLOSPO_RS14090 61abdb8167fb61c4360eaff8ed28c1d8 413 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 14 180 2.5E-45 T 09-11-2016 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CLOSPO_RS14090 61abdb8167fb61c4360eaff8ed28c1d8 413 SUPERFAMILY SSF53756 91 367 4.71E-33 T 09-11-2016 CLOSPO_RS14090 61abdb8167fb61c4360eaff8ed28c1d8 413 PANTHER PTHR21015 1 388 2.3E-136 T 09-11-2016 CLOSPO_RS14090 61abdb8167fb61c4360eaff8ed28c1d8 413 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 206 343 6.1E-11 T 09-11-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 CLOSPO_RS14090 61abdb8167fb61c4360eaff8ed28c1d8 413 PANTHER PTHR21015:SF21 1 388 2.3E-136 T 09-11-2016 CLOSPO_RS12875 d8ac1065da8605f6611031c748be314e 395 PANTHER PTHR40032:SF1 2 394 8.3E-242 T 09-11-2016 CLOSPO_RS12875 d8ac1065da8605f6611031c748be314e 395 Pfam PF12671 Putative amidase domain 215 391 3.6E-46 T 09-11-2016 IPR024301 Putative amidase domain CLOSPO_RS12875 d8ac1065da8605f6611031c748be314e 395 PANTHER PTHR40032 2 394 8.3E-242 T 09-11-2016 CLOSPO_RS16235 87874fde9328db80fce18e7ec5e361bc 48 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 38 3.5E-13 T 09-11-2016 IPR027601 Cys-rich peptide, Clo7bot family CLOSPO_RS17585 59824c9196afc51b80e413e4a792107b 66 SUPERFAMILY SSF55331 2 57 1.83E-12 T 09-11-2016 IPR014347 Tautomerase/MIF superfamily CLOSPO_RS17585 59824c9196afc51b80e413e4a792107b 66 Pfam PF01361 Tautomerase enzyme 5 58 4.2E-14 T 09-11-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CLOSPO_RS17585 59824c9196afc51b80e413e4a792107b 66 Gene3D G3DSA:3.30.429.20 2 55 7.9E-15 T 09-11-2016 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 PRINTS PR00946 Mercury scavenger protein signature 8 19 1.6E-8 T 09-11-2016 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 PRINTS PR00946 Mercury scavenger protein signature 65 79 1.6E-8 T 09-11-2016 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 PRINTS PR00946 Mercury scavenger protein signature 19 35 1.6E-8 T 09-11-2016 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 PRINTS PR00946 Mercury scavenger protein signature 35 50 1.6E-8 T 09-11-2016 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 ProSitePatterns PS00050 Ribosomal protein L23 signature. 48 63 - T 09-11-2016 IPR001014 Ribosomal protein L23/L25, conserved site CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 Pfam PF00403 Heavy-metal-associated domain 14 75 2.0E-12 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 SUPERFAMILY SSF55008 10 77 2.09E-18 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS17105 e562d5a2fa6abe075bff2f478cb48cca 79 Gene3D G3DSA:3.30.70.100 11 77 1.6E-19 T 09-11-2016 CLOSPO_RS18320 630a46ebfdb15b5e025000b1cbc9d393 197 PANTHER PTHR35332:SF2 5 197 1.3E-76 T 09-11-2016 CLOSPO_RS18320 630a46ebfdb15b5e025000b1cbc9d393 197 PIRSF PIRSF022704 1 197 4.6E-67 T 09-11-2016 IPR015987 Uncharacterised conserved protein UCP022704 CLOSPO_RS18320 630a46ebfdb15b5e025000b1cbc9d393 197 PANTHER PTHR35332 5 197 1.3E-76 T 09-11-2016 CLOSPO_RS18320 630a46ebfdb15b5e025000b1cbc9d393 197 SUPERFAMILY SSF49899 11 190 1.94E-41 T 09-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain CLOSPO_RS18320 630a46ebfdb15b5e025000b1cbc9d393 197 Pfam PF07081 Protein of unknown function (DUF1349) 11 190 1.7E-67 T 09-11-2016 IPR009784 Protein of unknown function DUF1349 CLOSPO_RS18320 630a46ebfdb15b5e025000b1cbc9d393 197 Gene3D G3DSA:2.60.120.200 15 190 2.1E-43 T 09-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain CLOSPO_RS08820 d319b669bc3f8fb6c6e84aa6a88255dc 279 PANTHER PTHR30290 13 279 1.6E-96 T 09-11-2016 CLOSPO_RS08820 d319b669bc3f8fb6c6e84aa6a88255dc 279 Gene3D G3DSA:3.90.76.10 26 196 9.4E-50 T 09-11-2016 CLOSPO_RS08820 d319b669bc3f8fb6c6e84aa6a88255dc 279 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 267 1.9E-46 T 09-11-2016 IPR000914 Solute-binding protein family 5 domain CLOSPO_RS08820 d319b669bc3f8fb6c6e84aa6a88255dc 279 Gene3D G3DSA:3.40.190.10 197 277 1.1E-17 T 09-11-2016 CLOSPO_RS08820 d319b669bc3f8fb6c6e84aa6a88255dc 279 SUPERFAMILY SSF53850 12 275 4.89E-65 T 09-11-2016 CLOSPO_RS08820 d319b669bc3f8fb6c6e84aa6a88255dc 279 PANTHER PTHR30290:SF10 13 279 1.6E-96 T 09-11-2016 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 Gene3D G3DSA:3.30.565.10 148 317 7.4E-28 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 PRINTS PR00344 Bacterial sensor protein C-terminal signature 262 272 8.5E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 PRINTS PR00344 Bacterial sensor protein C-terminal signature 244 258 8.5E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 PRINTS PR00344 Bacterial sensor protein C-terminal signature 279 297 8.5E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 315 8.5E-9 T 09-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 208 313 2.1E-15 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 Pfam PF00672 HAMP domain 16 82 6.2E-7 T 09-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 SMART SM00387 207 318 8.0E-21 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 Gene3D G3DSA:1.10.287.130 86 147 1.2E-17 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 SMART SM00388 94 161 5.1E-14 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 SUPERFAMILY SSF55874 165 316 1.57E-28 T 09-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 PANTHER PTHR24423 26 318 2.7E-65 T 09-11-2016 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 PANTHER PTHR24423:SF526 26 318 2.7E-65 T 09-11-2016 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 SUPERFAMILY SSF47384 80 161 1.02E-17 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS13375 f8a15d76b4bab996e6ba0b32292876fd 320 Pfam PF00512 His Kinase A (phospho-acceptor) domain 95 160 1.5E-13 T 09-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOSPO_RS18005 d942e04e1f96f6325086fc34cdb368de 215 SUPERFAMILY SSF51735 7 103 9.45E-10 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18005 d942e04e1f96f6325086fc34cdb368de 215 Pfam PF13241 Putative NAD(P)-binding 8 109 9.5E-14 T 09-11-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 CLOSPO_RS18005 d942e04e1f96f6325086fc34cdb368de 215 PANTHER PTHR35330 3 212 1.0E-49 T 09-11-2016 CLOSPO_RS18005 d942e04e1f96f6325086fc34cdb368de 215 Gene3D G3DSA:3.40.50.720 8 111 2.3E-20 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 SUPERFAMILY SSF52402 18 219 6.4E-35 T 09-11-2016 CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 PANTHER PTHR11807:SF17 5 268 4.4E-80 T 09-11-2016 CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 PANTHER PTHR11807 5 268 4.4E-80 T 09-11-2016 CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 PIRSF PIRSF006661 1 268 1.6E-104 T 09-11-2016 IPR005232 Conserved hypothetical protein CHP00268 CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 Pfam PF02540 NAD synthase 16 79 2.2E-6 T 09-11-2016 IPR022310 NAD/GMP synthase CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 259 1.3E-84 T 09-11-2016 IPR005232 Conserved hypothetical protein CHP00268 CLOSPO_RS14205 d6292f08e390ad07816cc7ee0a451a2d 268 Gene3D G3DSA:3.40.50.620 18 169 4.2E-27 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS16410 73d18d2c65bcede38bb26dc42420b892 238 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 100 219 4.7E-36 T 09-11-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CLOSPO_RS16410 73d18d2c65bcede38bb26dc42420b892 238 SUPERFAMILY SSF55166 83 227 7.85E-32 T 09-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain CLOSPO_RS16410 73d18d2c65bcede38bb26dc42420b892 238 PANTHER PTHR34385:SF1 11 236 6.2E-82 T 09-11-2016 CLOSPO_RS16410 73d18d2c65bcede38bb26dc42420b892 238 PANTHER PTHR34385 11 236 6.2E-82 T 09-11-2016 CLOSPO_RS15830 2d212a8f19231c139e87413936cbef3d 156 Gene3D G3DSA:3.30.1360.40 104 145 9.4E-4 T 09-11-2016 IPR024946 Arginine repressor C-terminal-like domain CLOSPO_RS16125 32cef6dfa0b9849c19fbffb1fd88d1b1 378 Gene3D G3DSA:3.10.450.50 341 376 7.3E-10 T 09-11-2016 IPR032710 NTF2-like domain CLOSPO_RS16125 32cef6dfa0b9849c19fbffb1fd88d1b1 378 Pfam PF02810 SEC-C motif 359 376 3.0E-10 T 09-11-2016 IPR004027 SEC-C motif CLOSPO_RS16125 32cef6dfa0b9849c19fbffb1fd88d1b1 378 SUPERFAMILY SSF103642 357 377 1.24E-7 T 09-11-2016 CLOSPO_RS16125 32cef6dfa0b9849c19fbffb1fd88d1b1 378 PANTHER PTHR33747 222 377 3.4E-22 T 09-11-2016 CLOSPO_RS16125 32cef6dfa0b9849c19fbffb1fd88d1b1 378 PANTHER PTHR33747:SF1 222 377 3.4E-22 T 09-11-2016 CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 SMART SM01011 1 135 1.5E-34 T 09-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 Gene3D G3DSA:3.40.350.10 2 175 1.0E-38 T 09-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 SUPERFAMILY SSF53092 2 171 3.4E-34 T 09-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 SUPERFAMILY SSF55920 172 410 7.59E-71 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 Gene3D G3DSA:3.90.230.10 176 411 1.1E-75 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 PANTHER PTHR10804:SF17 1 410 2.8E-130 T 09-11-2016 CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 PANTHER PTHR10804 1 410 2.8E-130 T 09-11-2016 CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 120 3.6E-27 T 09-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CLOSPO_RS16050 d654c2bcd0320526e090dcc053284b7c 411 Pfam PF00557 Metallopeptidase family M24 177 389 3.6E-59 T 09-11-2016 IPR000994 Peptidase M24, structural domain CLOSPO_RS13745 3abdc8060d059998a70fa9ad85f965c5 345 Pfam PF04245 37-kD nucleoid-associated bacterial protein 13 343 1.0E-73 T 09-11-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 CLOSPO_RS15040 d4b508b069fbea658b76c0e7bda9fa0d 182 SUPERFAMILY SSF55144 1 179 3.84E-22 T 09-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CLOSPO_RS15040 d4b508b069fbea658b76c0e7bda9fa0d 182 Gene3D G3DSA:3.90.1140.10 1 172 1.4E-17 T 09-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CLOSPO_RS15040 d4b508b069fbea658b76c0e7bda9fa0d 182 Pfam PF13563 2'-5' RNA ligase superfamily 14 140 2.7E-9 T 09-11-2016 CLOSPO_RS17255 7e22936cedc38e63acb7cf8fae87086f 404 SUPERFAMILY SSF53850 39 400 6.52E-48 T 09-11-2016 CLOSPO_RS17255 7e22936cedc38e63acb7cf8fae87086f 404 TIGRFAM TIGR04541 thiaminase_BcmE: thiamine pyridinylase 11 392 1.2E-207 T 09-11-2016 IPR030901 Thiamine pyridinylase KEGG: 00730+2.5.1.2 CLOSPO_RS17255 7e22936cedc38e63acb7cf8fae87086f 404 Gene3D G3DSA:3.40.190.10 56 151 1.3E-8 T 09-11-2016 CLOSPO_RS17255 7e22936cedc38e63acb7cf8fae87086f 404 Gene3D G3DSA:3.40.190.10 152 333 2.0E-87 T 09-11-2016 CLOSPO_RS17255 7e22936cedc38e63acb7cf8fae87086f 404 Pfam PF01547 Bacterial extracellular solute-binding protein 55 323 3.7E-4 T 09-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CLOSPO_RS17130 c5804f2ca50240344f38a192de5b0d83 202 Pfam PF06114 Domain of unknown function (DUF955) 103 180 5.5E-13 T 09-11-2016 IPR010359 HTH domain, IrrE-type CLOSPO_RS17990 5d45a665c3484622fdb53395019f8cb2 239 PANTHER PTHR34229:SF2 25 236 2.7E-116 T 09-11-2016 CLOSPO_RS17990 5d45a665c3484622fdb53395019f8cb2 239 PANTHER PTHR34229 25 236 2.7E-116 T 09-11-2016 CLOSPO_RS17990 5d45a665c3484622fdb53395019f8cb2 239 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 24 236 28.078 T 09-11-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 UniPathway: UPA00148 CLOSPO_RS17990 5d45a665c3484622fdb53395019f8cb2 239 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 25 231 3.4E-57 T 09-11-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 CLOSPO_RS17990 5d45a665c3484622fdb53395019f8cb2 239 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 24 231 3.6E-86 T 09-11-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 UniPathway: UPA00148 CLOSPO_RS16250 bc3ffe6fe2799977edb7c056e4fd2505 165 Gene3D G3DSA:3.40.630.30 3 151 2.7E-12 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS16250 bc3ffe6fe2799977edb7c056e4fd2505 165 SUPERFAMILY SSF55729 4 145 6.34E-11 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS12820 29dbe7d32f09031e927e84f5925df2f3 310 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 6 309 26.433 T 09-11-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 CLOSPO_RS12820 29dbe7d32f09031e927e84f5925df2f3 310 Pfam PF03116 NQR2, RnfD, RnfE family 8 307 2.8E-125 T 09-11-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 CLOSPO_RS12820 29dbe7d32f09031e927e84f5925df2f3 310 PANTHER PTHR30578 1 310 6.6E-132 T 09-11-2016 CLOSPO_RS12820 29dbe7d32f09031e927e84f5925df2f3 310 PANTHER PTHR30578:SF0 1 310 6.6E-132 T 09-11-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 CLOSPO_RS12820 29dbe7d32f09031e927e84f5925df2f3 310 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 11 308 1.5E-108 T 09-11-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 CLOSPO_RS13400 9e34045cced10c0986eab9f366e94b06 323 SUPERFAMILY SSF53474 40 320 1.82E-24 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS13400 9e34045cced10c0986eab9f366e94b06 323 Gene3D G3DSA:3.40.50.1820 44 320 6.9E-27 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS13400 9e34045cced10c0986eab9f366e94b06 323 PANTHER PTHR10992 45 320 2.5E-17 T 09-11-2016 CLOSPO_RS13400 9e34045cced10c0986eab9f366e94b06 323 Pfam PF00561 alpha/beta hydrolase fold 63 175 2.4E-8 T 09-11-2016 IPR000073 Alpha/beta hydrolase fold-1 CLOSPO_RS14640 0b1365028625b766191d6cf8a9f1f65e 65 PANTHER PTHR38455 2 65 4.9E-33 T 09-11-2016 CLOSPO_RS14640 0b1365028625b766191d6cf8a9f1f65e 65 PIRSF PIRSF037263 1 65 5.7E-35 T 09-11-2016 IPR009296 Protein of unknown function DUF951 CLOSPO_RS14640 0b1365028625b766191d6cf8a9f1f65e 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 5 58 9.2E-32 T 09-11-2016 IPR009296 Protein of unknown function DUF951 CLOSPO_RS14640 0b1365028625b766191d6cf8a9f1f65e 65 PANTHER PTHR38455:SF1 2 65 4.9E-33 T 09-11-2016 CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 SMART SM00849 13 225 7.8E-12 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 Pfam PF10996 Beta-Casp domain 252 377 1.3E-29 T 09-11-2016 IPR022712 Beta-Casp domain CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 PANTHER PTHR11203 1 467 2.1E-147 T 09-11-2016 CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 SMART SM01027 252 377 9.3E-60 T 09-11-2016 IPR022712 Beta-Casp domain CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 PANTHER PTHR11203:SF11 1 467 2.1E-147 T 09-11-2016 CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 391 452 1.7E-14 T 09-11-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 SUPERFAMILY SSF56281 1 464 4.06E-131 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 Pfam PF00753 Metallo-beta-lactamase superfamily 13 72 8.8E-11 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 Gene3D G3DSA:3.60.15.10 1 99 2.1E-52 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS18990 11d99b94de5d6f4112e0dd2aa088f2e6 502 Gene3D G3DSA:3.60.15.10 135 261 2.1E-52 T 09-11-2016 IPR001279 Metallo-beta-lactamase CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 PANTHER PTHR11776 2 188 2.3E-81 T 09-11-2016 CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 Gene3D G3DSA:3.40.50.2020 2 188 1.8E-59 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 38.875 T 09-11-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 SUPERFAMILY SSF53271 2 187 9.94E-44 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 189 1.0E-75 T 09-11-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 PANTHER PTHR11776:SF1 2 188 2.3E-81 T 09-11-2016 CLOSPO_RS13095 2d75c123cf64aa8eb350638cc89c2a3e 190 Pfam PF00156 Phosphoribosyl transferase domain 38 162 2.0E-9 T 09-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOSPO_RS14200 b5c904e1014d942f8245e1cb71806f29 248 SMART SM01001 119 248 5.0E-37 T 09-11-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 CLOSPO_RS14200 b5c904e1014d942f8245e1cb71806f29 248 PANTHER PTHR23046 2 248 7.7E-127 T 09-11-2016 CLOSPO_RS14200 b5c904e1014d942f8245e1cb71806f29 248 Gene3D G3DSA:3.40.50.7700 120 246 5.8E-26 T 09-11-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 CLOSPO_RS14200 b5c904e1014d942f8245e1cb71806f29 248 PANTHER PTHR23046:SF3 2 248 7.7E-127 T 09-11-2016 CLOSPO_RS14200 b5c904e1014d942f8245e1cb71806f29 248 SUPERFAMILY SSF52255 119 247 1.24E-29 T 09-11-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 CLOSPO_RS14200 b5c904e1014d942f8245e1cb71806f29 248 Pfam PF00731 AIR carboxylase 121 245 9.9E-16 T 09-11-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 CLOSPO_RS08270 ec5122672f71e78f8a2a181e056cd2c7 115 Gene3D G3DSA:3.90.1300.10 5 115 9.9E-36 T 09-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08270 ec5122672f71e78f8a2a181e056cd2c7 115 PANTHER PTHR11895:SF75 1 115 2.1E-54 T 09-11-2016 CLOSPO_RS08270 ec5122672f71e78f8a2a181e056cd2c7 115 PANTHER PTHR11895 1 115 2.1E-54 T 09-11-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08270 ec5122672f71e78f8a2a181e056cd2c7 115 Pfam PF01425 Amidase 2 115 1.1E-32 T 09-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS08270 ec5122672f71e78f8a2a181e056cd2c7 115 SUPERFAMILY SSF75304 2 115 8.24E-33 T 09-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOSPO_RS10995 c2b67a46c6eef11c3f5da8a1e2e043c1 67 PANTHER PTHR32154:SF0 1 67 1.3E-45 T 09-11-2016 CLOSPO_RS10995 c2b67a46c6eef11c3f5da8a1e2e043c1 67 SUPERFAMILY SSF52518 2 65 1.24E-26 T 09-11-2016 IPR029061 Thiamin diphosphate-binding fold CLOSPO_RS10995 c2b67a46c6eef11c3f5da8a1e2e043c1 67 Gene3D G3DSA:3.40.50.970 2 66 8.2E-27 T 09-11-2016 IPR029061 Thiamin diphosphate-binding fold CLOSPO_RS10995 c2b67a46c6eef11c3f5da8a1e2e043c1 67 PANTHER PTHR32154 1 67 1.3E-45 T 09-11-2016 CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 SUPERFAMILY SSF54001 658 761 3.73E-42 T 09-11-2016 CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Pfam PF08239 Bacterial SH3 domain 280 329 7.6E-14 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Pfam PF08239 Bacterial SH3 domain 196 246 2.2E-15 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Pfam PF08239 Bacterial SH3 domain 358 408 3.1E-14 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Pfam PF08239 Bacterial SH3 domain 436 487 2.9E-15 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Pfam PF05257 CHAP domain 53 137 4.2E-13 T 09-11-2016 IPR007921 CHAP domain CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 SMART SM00287 188 250 8.0E-8 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 SMART SM00287 426 490 4.0E-10 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 SMART SM00287 349 411 1.2E-9 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 SMART SM00287 269 332 7.8E-11 T 09-11-2016 IPR003646 SH3-like domain, bacterial-type CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 PANTHER PTHR21666 651 764 9.3E-40 T 09-11-2016 CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Gene3D G3DSA:3.90.1720.10 656 761 1.6E-45 T 09-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 SUPERFAMILY SSF54001 35 163 1.47E-18 T 09-11-2016 CLOSPO_RS15870 c8df3ea01912909f422297728949ce77 770 Pfam PF00877 NlpC/P60 family 673 760 7.1E-28 T 09-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- CLOSPO_RS18595 b09cc64fbff785609362561cce424f6a 48 Pfam PF12669 Virus attachment protein p12 family 2 42 7.4E-11 T 09-11-2016 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 SMART SM00382 377 563 8.6E-13 T 09-11-2016 IPR003593 AAA+ ATPase domain CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 Pfam PF00005 ABC transporter 368 517 5.5E-31 T 09-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 Gene3D G3DSA:1.20.1560.10 10 331 4.8E-45 T 09-11-2016 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 PANTHER PTHR24222:SF23 1 599 0.0 T 09-11-2016 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 SUPERFAMILY SSF90123 3 335 3.01E-47 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 PANTHER PTHR24222 1 599 0.0 T 09-11-2016 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 Gene3D G3DSA:3.40.50.300 347 582 3.0E-75 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 Pfam PF00664 ABC transporter transmembrane region 28 292 8.4E-18 T 09-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CLOSPO_RS18730 98f0d184a7502d1a111e215bdd344de1 600 SUPERFAMILY SSF52540 340 587 1.11E-87 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS13160 2e2c434cbe4863607c201296f9428389 334 PANTHER PTHR10584:SF203 1 334 2.5E-124 T 09-11-2016 CLOSPO_RS13160 2e2c434cbe4863607c201296f9428389 334 Pfam PF00294 pfkB family carbohydrate kinase 18 311 6.4E-37 T 09-11-2016 IPR011611 Carbohydrate kinase PfkB CLOSPO_RS13160 2e2c434cbe4863607c201296f9428389 334 SUPERFAMILY SSF53613 1 325 2.76E-69 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS13160 2e2c434cbe4863607c201296f9428389 334 PANTHER PTHR10584 1 334 2.5E-124 T 09-11-2016 CLOSPO_RS13160 2e2c434cbe4863607c201296f9428389 334 Gene3D G3DSA:3.40.1190.20 1 328 2.3E-76 T 09-11-2016 IPR029056 Ribokinase-like CLOSPO_RS16015 f9d018175b722111b8f1f322b6cf4157 178 PANTHER PTHR33567 3 178 1.4E-93 T 09-11-2016 CLOSPO_RS16015 f9d018175b722111b8f1f322b6cf4157 178 PANTHER PTHR33567:SF2 3 178 1.4E-93 T 09-11-2016 CLOSPO_RS16015 f9d018175b722111b8f1f322b6cf4157 178 Pfam PF02417 Chromate transporter 5 169 9.0E-50 T 09-11-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 CLOSPO_RS12760 5701380459e59e2cbc7998096b7b2fd4 760 Gene3D G3DSA:2.130.10.10 476 611 9.8E-8 T 09-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CLOSPO_RS12760 5701380459e59e2cbc7998096b7b2fd4 760 Gene3D G3DSA:2.130.10.10 176 306 9.8E-8 T 09-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CLOSPO_RS12760 5701380459e59e2cbc7998096b7b2fd4 760 Gene3D G3DSA:2.140.10.10 633 693 6.9E-6 T 09-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CLOSPO_RS12760 5701380459e59e2cbc7998096b7b2fd4 760 SUPERFAMILY SSF50998 389 523 4.16E-15 T 09-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CLOSPO_RS12760 5701380459e59e2cbc7998096b7b2fd4 760 SUPERFAMILY SSF50998 587 694 4.16E-15 T 09-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CLOSPO_RS12760 5701380459e59e2cbc7998096b7b2fd4 760 SUPERFAMILY SSF50998 168 266 4.16E-15 T 09-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CLOSPO_RS13775 882af4c8c8e045736b3b233dadddbefc 134 SMART SM00450 36 131 3.1E-15 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13775 882af4c8c8e045736b3b233dadddbefc 134 Pfam PF00581 Rhodanese-like domain 38 123 1.0E-17 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13775 882af4c8c8e045736b3b233dadddbefc 134 SUPERFAMILY SSF52821 15 123 1.96E-29 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS13775 882af4c8c8e045736b3b233dadddbefc 134 Gene3D G3DSA:3.40.250.10 23 123 2.5E-28 T 09-11-2016 IPR001763 Rhodanese-like domain CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 Pfam PF04122 Putative cell wall binding repeat 2 38 124 9.7E-19 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 Pfam PF04122 Putative cell wall binding repeat 2 231 318 1.0E-16 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 Pfam PF04122 Putative cell wall binding repeat 2 137 222 4.2E-19 T 09-11-2016 IPR007253 Putative cell wall binding repeat 2 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 PANTHER PTHR30032:SF1 382 612 2.3E-163 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 PANTHER PTHR30032:SF1 4 288 2.3E-163 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 SUPERFAMILY SSF89260 441 538 5.62E-11 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 Gene3D G3DSA:2.60.120.380 437 554 3.4E-24 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 Gene3D G3DSA:2.60.120.380 559 672 6.6E-22 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 Gene3D G3DSA:2.60.120.380 341 433 5.2E-10 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 SUPERFAMILY SSF89260 562 671 5.75E-12 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 PANTHER PTHR30032 382 612 2.3E-163 T 09-11-2016 CLOSPO_RS12770 0ed9fb11153664ccfaa4f6b7a9691c1d 685 PANTHER PTHR30032 4 288 2.3E-163 T 09-11-2016 CLOSPO_RS17310 1b656ba617907511193113a8c48a7110 97 Pfam PF09458 H-type lectin domain 30 95 3.1E-20 T 09-11-2016 IPR019019 H-type lectin domain GO:0007155|GO:0030246 CLOSPO_RS17310 1b656ba617907511193113a8c48a7110 97 SUPERFAMILY SSF141086 19 96 3.4E-25 T 09-11-2016 CLOSPO_RS16550 7fdf91b3f3f8130ab1aff08eff601f12 103 SUPERFAMILY SSF48150 36 95 1.94E-8 T 09-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 CLOSPO_RS16550 7fdf91b3f3f8130ab1aff08eff601f12 103 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 95 5.3E-6 T 09-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 CLOSPO_RS16550 7fdf91b3f3f8130ab1aff08eff601f12 103 Gene3D G3DSA:1.10.340.30 39 95 2.4E-8 T 09-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 CLOSPO_RS18585 a47b2b15a2d0c24f10e54600a5a03bb1 73 Pfam PF04023 FeoA domain 2 73 1.6E-15 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS18585 a47b2b15a2d0c24f10e54600a5a03bb1 73 SUPERFAMILY SSF50037 6 73 1.98E-20 T 09-11-2016 IPR008988 Transcriptional repressor, C-terminal CLOSPO_RS18585 a47b2b15a2d0c24f10e54600a5a03bb1 73 PANTHER PTHR33238 1 72 1.3E-17 T 09-11-2016 CLOSPO_RS18585 a47b2b15a2d0c24f10e54600a5a03bb1 73 SMART SM00899 2 73 1.3E-18 T 09-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOSPO_RS12865 eeec2372031e4cb0f83a17c163a23dc6 188 PANTHER PTHR38659:SF1 2 188 4.2E-115 T 09-11-2016 CLOSPO_RS12865 eeec2372031e4cb0f83a17c163a23dc6 188 Pfam PF01966 HD domain 21 99 1.0E-6 T 09-11-2016 IPR006674 HD domain CLOSPO_RS12865 eeec2372031e4cb0f83a17c163a23dc6 188 Gene3D G3DSA:1.10.3210.10 2 182 4.0E-28 T 09-11-2016 IPR006674 HD domain CLOSPO_RS12865 eeec2372031e4cb0f83a17c163a23dc6 188 PANTHER PTHR38659 2 188 4.2E-115 T 09-11-2016 CLOSPO_RS12865 eeec2372031e4cb0f83a17c163a23dc6 188 SUPERFAMILY SSF109604 11 176 5.42E-17 T 09-11-2016 CLOSPO_RS15770 da7a0f3aebf9e428aa687ee2b25ca010 452 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 69 421 4.6E-51 T 09-11-2016 IPR003776 YcaO-like domain CLOSPO_RS15770 da7a0f3aebf9e428aa687ee2b25ca010 452 PANTHER PTHR37809 67 452 3.7E-20 T 09-11-2016 CLOSPO_RS15770 da7a0f3aebf9e428aa687ee2b25ca010 452 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 69 452 2.1E-111 T 09-11-2016 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 PANTHER PTHR30126 2 291 6.7E-110 T 09-11-2016 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.7E-10 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.7E-10 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.7E-10 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 Gene3D G3DSA:1.10.10.10 4 83 1.3E-23 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 Pfam PF03466 LysR substrate binding domain 93 291 2.0E-28 T 09-11-2016 IPR005119 LysR, substrate-binding CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 SUPERFAMILY SSF46785 4 113 3.22E-20 T 09-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 9.6E-19 T 09-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 PANTHER PTHR30126:SF13 2 291 6.7E-110 T 09-11-2016 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 SUPERFAMILY SSF53850 92 291 5.65E-32 T 09-11-2016 CLOSPO_RS16680 874ee3457003523bdad6ec374f405735 291 Gene3D G3DSA:3.40.190.10 90 226 1.6E-24 T 09-11-2016 CLOSPO_RS17520 8bd769f1f0b01616259696eef0346197 93 Pfam PF14898 Domain of unknown function (DUF4491) 3 93 1.2E-34 T 09-11-2016 IPR027890 Protein of unknown function DUF4491 CLOSPO_RS14020 41f63b63f20b0e97bb327910f6d13fbc 220 Pfam PF02535 ZIP Zinc transporter 73 213 4.6E-25 T 09-11-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CLOSPO_RS14020 41f63b63f20b0e97bb327910f6d13fbc 220 PANTHER PTHR11040 1 212 9.0E-40 T 09-11-2016 CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 PANTHER PTHR18964:SF123 1 312 5.1E-102 T 09-11-2016 CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 310 9.2E-80 T 09-11-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 Pfam PF00480 ROK family 7 310 1.5E-80 T 09-11-2016 IPR000600 ROK family CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 Gene3D G3DSA:3.30.420.40 2 141 7.9E-49 T 09-11-2016 CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 Gene3D G3DSA:3.30.420.40 142 295 6.3E-58 T 09-11-2016 CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 PANTHER PTHR18964 1 312 5.1E-102 T 09-11-2016 CLOSPO_RS18765 79d1029151b0e79409aecabf4f68a2f8 315 SUPERFAMILY SSF53067 5 312 6.26E-72 T 09-11-2016 CLOSPO_RS17830 7d73d946cbd0197f8fb146fade702a4a 203 Gene3D G3DSA:3.20.80.10 56 203 1.3E-27 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17830 7d73d946cbd0197f8fb146fade702a4a 203 SUPERFAMILY SSF55136 58 201 8.02E-19 T 09-11-2016 IPR011256 Regulatory factor, effector binding domain CLOSPO_RS17830 7d73d946cbd0197f8fb146fade702a4a 203 SMART SM00871 57 202 1.0E-4 T 09-11-2016 IPR010499 Bacterial transcription activator, effector binding CLOSPO_RS18100 8cfed499e1407cf636a0149766f9c8ff 151 Gene3D G3DSA:3.40.630.30 3 137 2.8E-23 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18100 8cfed499e1407cf636a0149766f9c8ff 151 Pfam PF13673 Acetyltransferase (GNAT) domain 40 134 3.5E-9 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18100 8cfed499e1407cf636a0149766f9c8ff 151 SUPERFAMILY SSF55729 1 137 5.98E-24 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18100 8cfed499e1407cf636a0149766f9c8ff 151 PANTHER PTHR23091:SF130 1 136 7.2E-15 T 09-11-2016 CLOSPO_RS18100 8cfed499e1407cf636a0149766f9c8ff 151 PANTHER PTHR23091 1 136 7.2E-15 T 09-11-2016 CLOSPO_RS17805 5d1969ef677d3c222669b5976e1adf89 59 Pfam PF09388 Spo0E like sporulation regulatory protein 7 50 4.3E-11 T 09-11-2016 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CLOSPO_RS17805 5d1969ef677d3c222669b5976e1adf89 59 SUPERFAMILY SSF140500 3 55 1.57E-7 T 09-11-2016 CLOSPO_RS08460 c519d2ef60ea7dc1d58587c6dc67a605 67 PANTHER PTHR30191 1 67 1.5E-19 T 09-11-2016 CLOSPO_RS08460 c519d2ef60ea7dc1d58587c6dc67a605 67 Gene3D G3DSA:3.20.70.20 2 56 2.6E-10 T 09-11-2016 CLOSPO_RS08460 c519d2ef60ea7dc1d58587c6dc67a605 67 SUPERFAMILY SSF51998 2 61 1.74E-9 T 09-11-2016 CLOSPO_RS08460 c519d2ef60ea7dc1d58587c6dc67a605 67 PANTHER PTHR30191:SF0 1 67 1.5E-19 T 09-11-2016 CLOSPO_RS04550 02ea66938cfb1b4bf73f4e165e2002d0 106 Gene3D G3DSA:1.10.1740.10 3 78 1.1E-7 T 09-11-2016 CLOSPO_RS04550 02ea66938cfb1b4bf73f4e165e2002d0 106 Pfam PF04542 Sigma-70 region 2 3 66 8.5E-8 T 09-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS04550 02ea66938cfb1b4bf73f4e165e2002d0 106 SUPERFAMILY SSF88946 2 78 1.22E-8 T 09-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOSPO_RS14265 270b6b9bc2a5a8cd96c53aa5882b5e05 713 PANTHER PTHR21075 1 709 2.3E-246 T 09-11-2016 CLOSPO_RS14265 270b6b9bc2a5a8cd96c53aa5882b5e05 713 Pfam PF03477 ATP cone domain 3 91 1.7E-18 T 09-11-2016 IPR005144 ATP-cone domain CLOSPO_RS14265 270b6b9bc2a5a8cd96c53aa5882b5e05 713 Gene3D G3DSA:3.20.70.20 120 684 2.4E-168 T 09-11-2016 CLOSPO_RS14265 270b6b9bc2a5a8cd96c53aa5882b5e05 713 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 114 701 5.8E-181 T 09-11-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 CLOSPO_RS14265 270b6b9bc2a5a8cd96c53aa5882b5e05 713 SUPERFAMILY SSF51998 115 685 7.02E-156 T 09-11-2016 CLOSPO_RS14265 270b6b9bc2a5a8cd96c53aa5882b5e05 713 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 114 702 9.8E-194 T 09-11-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 CLOSPO_RS17240 ce8aa87c3f2b19a9194d1cf2ae919ce1 153 Gene3D G3DSA:3.40.50.1810 2 125 4.5E-9 T 09-11-2016 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 CLOSPO_RS17240 ce8aa87c3f2b19a9194d1cf2ae919ce1 153 SUPERFAMILY SSF52309 2 136 3.43E-18 T 09-11-2016 CLOSPO_RS16810 eabc4dfd979235d62acd08e58ddb6504 323 Gene3D G3DSA:3.40.50.2300 28 157 5.4E-55 T 09-11-2016 CLOSPO_RS16810 eabc4dfd979235d62acd08e58ddb6504 323 Gene3D G3DSA:3.40.50.2300 158 288 4.0E-51 T 09-11-2016 CLOSPO_RS16810 eabc4dfd979235d62acd08e58ddb6504 323 SUPERFAMILY SSF53822 40 286 1.39E-11 T 09-11-2016 IPR028082 Periplasmic binding protein-like I CLOSPO_RS16810 eabc4dfd979235d62acd08e58ddb6504 323 PANTHER PTHR35271 1 322 3.5E-75 T 09-11-2016 CLOSPO_RS16810 eabc4dfd979235d62acd08e58ddb6504 323 Pfam PF04392 ABC transporter substrate binding protein 32 308 9.0E-83 T 09-11-2016 IPR007487 ABC transporter, substrate-binding protein CLOSPO_RS17665 2114abab9e4763d0b249af3a0d7f57e3 233 PANTHER PTHR13903:SF7 7 233 6.7E-111 T 09-11-2016 CLOSPO_RS17665 2114abab9e4763d0b249af3a0d7f57e3 233 Pfam PF02678 Pirin 15 118 2.4E-31 T 09-11-2016 IPR003829 Pirin, N-terminal domain CLOSPO_RS17665 2114abab9e4763d0b249af3a0d7f57e3 233 Gene3D G3DSA:2.60.120.10 5 230 2.0E-62 T 09-11-2016 IPR014710 RmlC-like jelly roll fold CLOSPO_RS17665 2114abab9e4763d0b249af3a0d7f57e3 233 SUPERFAMILY SSF51182 4 229 1.86E-66 T 09-11-2016 IPR011051 RmlC-like cupin domain CLOSPO_RS17665 2114abab9e4763d0b249af3a0d7f57e3 233 PANTHER PTHR13903 7 233 6.7E-111 T 09-11-2016 IPR012093 Pirin CLOSPO_RS17665 2114abab9e4763d0b249af3a0d7f57e3 233 PIRSF PIRSF006232 1 232 1.1E-53 T 09-11-2016 IPR012093 Pirin CLOSPO_RS15430 35a8ffe50abbbed817c3499745caf206 452 Gene3D G3DSA:3.20.20.70 35 395 1.5E-70 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS15430 35a8ffe50abbbed817c3499745caf206 452 SUPERFAMILY SSF51569 41 342 1.47E-57 T 09-11-2016 CLOSPO_RS15430 35a8ffe50abbbed817c3499745caf206 452 PANTHER PTHR10277 13 447 6.2E-241 T 09-11-2016 CLOSPO_RS15430 35a8ffe50abbbed817c3499745caf206 452 Pfam PF00682 HMGL-like 49 324 6.1E-27 T 09-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 CLOSPO_RS15430 35a8ffe50abbbed817c3499745caf206 452 PANTHER PTHR10277:SF46 13 447 6.2E-241 T 09-11-2016 CLOSPO_RS16230 c7f1ee7f195ed0837935181a4eda9a6e 34 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 33 2.7E-17 T 09-11-2016 IPR027601 Cys-rich peptide, Clo7bot family CLOSPO_RS12585 7d080a37f281de88942639fafa1e3f0b 371 Pfam PF01841 Transglutaminase-like superfamily 72 178 1.2E-4 T 09-11-2016 IPR002931 Transglutaminase-like CLOSPO_RS12585 7d080a37f281de88942639fafa1e3f0b 371 SUPERFAMILY SSF54001 70 187 9.81E-6 T 09-11-2016 CLOSPO_RS12610 ddb6a733713bc1321dca9281c126abd5 308 Pfam PF11155 Domain of unknown function (DUF2935) 9 176 8.0E-45 T 09-11-2016 IPR021328 Protein of unknown function DUF2935 CLOSPO_RS12610 ddb6a733713bc1321dca9281c126abd5 308 Pfam PF11155 Domain of unknown function (DUF2935) 190 302 7.8E-36 T 09-11-2016 IPR021328 Protein of unknown function DUF2935 CLOSPO_RS12610 ddb6a733713bc1321dca9281c126abd5 308 SUPERFAMILY SSF158430 116 188 6.93E-42 T 09-11-2016 CLOSPO_RS12610 ddb6a733713bc1321dca9281c126abd5 308 SUPERFAMILY SSF158430 8 67 6.93E-42 T 09-11-2016 CLOSPO_RS12610 ddb6a733713bc1321dca9281c126abd5 308 SUPERFAMILY SSF158430 181 305 5.49E-38 T 09-11-2016 CLOSPO_RS02920 98e61b490ae7fbb06b15ae5b352845d7 69 SUPERFAMILY SSF53623 5 69 1.83E-17 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS02920 98e61b490ae7fbb06b15ae5b352845d7 69 Gene3D G3DSA:3.40.1190.10 4 69 2.1E-20 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS02920 98e61b490ae7fbb06b15ae5b352845d7 69 PANTHER PTHR23135 1 69 6.2E-24 T 09-11-2016 CLOSPO_RS02920 98e61b490ae7fbb06b15ae5b352845d7 69 PANTHER PTHR23135:SF2 1 69 6.2E-24 T 09-11-2016 CLOSPO_RS02920 98e61b490ae7fbb06b15ae5b352845d7 69 Pfam PF08245 Mur ligase middle domain 3 69 6.6E-18 T 09-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 CLOSPO_RS13215 70f741378791c4894e7313422e7bee84 178 PANTHER PTHR41386 1 175 2.5E-61 T 09-11-2016 CLOSPO_RS13215 70f741378791c4894e7313422e7bee84 178 PANTHER PTHR41386:SF1 1 175 2.5E-61 T 09-11-2016 CLOSPO_RS13215 70f741378791c4894e7313422e7bee84 178 Pfam PF06210 Protein of unknown function (DUF1003) 63 163 2.9E-37 T 09-11-2016 IPR010406 Protein of unknown function DUF1003 CLOSPO_RS13370 050ad38b41d416847e95d33f3953e0c0 487 PANTHER PTHR11785 4 485 2.3E-212 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS13370 050ad38b41d416847e95d33f3953e0c0 487 PIRSF PIRSF006060 1 481 1.2E-84 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS13370 050ad38b41d416847e95d33f3953e0c0 487 Pfam PF00324 Amino acid permease 22 467 1.1E-132 T 09-11-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS13370 050ad38b41d416847e95d33f3953e0c0 487 PANTHER PTHR11785:SF204 4 485 2.3E-212 T 09-11-2016 CLOSPO_RS13935 6fb219ea3f2941e6db60142a48dcb195 235 Pfam PF08680 TATA-box binding 57 235 1.0E-8 T 09-11-2016 IPR014794 TATA-box binding CLOSPO_RS13935 6fb219ea3f2941e6db60142a48dcb195 235 Gene3D G3DSA:3.30.360.40 164 235 6.0E-7 T 09-11-2016 CLOSPO_RS13935 6fb219ea3f2941e6db60142a48dcb195 235 SUPERFAMILY SSF143842 32 231 1.31E-35 T 09-11-2016 IPR014794 TATA-box binding CLOSPO_RS14465 dd924ebd70cbec2e14b3076538728819 70 Pfam PF10764 Inhibitor of sigma-G Gin 6 50 1.8E-16 T 09-11-2016 IPR019700 Anti-sigma-G factor Gin CLOSPO_RS13055 58a96bada45073671ac22c520fef2e8e 119 Pfam PF03788 LrgA family 15 106 2.9E-31 T 09-11-2016 IPR005538 LrgA/CidA family GO:0016021 CLOSPO_RS13055 58a96bada45073671ac22c520fef2e8e 119 PANTHER PTHR33931 2 119 1.4E-41 T 09-11-2016 CLOSPO_RS13055 58a96bada45073671ac22c520fef2e8e 119 PANTHER PTHR33931:SF2 2 119 1.4E-41 T 09-11-2016 CLOSPO_RS17400 de41da91f1b94f5c29c46b5592cf62ec 565 Pfam PF09706 CRISPR-associated protein (Cas_CXXC_CXXC) 223 291 4.3E-10 T 09-11-2016 IPR019121 CRISPR-associated protein, CXXC-CXXC domain CLOSPO_RS17400 de41da91f1b94f5c29c46b5592cf62ec 565 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 224 513 5.5E-17 T 09-11-2016 IPR010180 CRISPR-associated protein, CXXC-CXXC CLOSPO_RS00305 d36e26556781dea1dacf5fe11781903f 132 PANTHER PTHR11017:SF153 2 132 2.1E-52 T 09-11-2016 CLOSPO_RS00305 d36e26556781dea1dacf5fe11781903f 132 Pfam PF13306 Leucine rich repeats (6 copies) 24 131 5.9E-29 T 09-11-2016 IPR026906 Leucine rich repeat 5 CLOSPO_RS00305 d36e26556781dea1dacf5fe11781903f 132 PANTHER PTHR11017 2 132 2.1E-52 T 09-11-2016 CLOSPO_RS12915 288ad33a8c1000d0445d1b17d6875aa4 768 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 287 314 6.7E-7 T 09-11-2016 IPR023908 xxxLxxG heptad repeat CLOSPO_RS12915 288ad33a8c1000d0445d1b17d6875aa4 768 SUPERFAMILY SSF58104 254 468 4.77E-9 T 09-11-2016 CLOSPO_RS17635 ed59eae80b32d270ef8e29342ad082bf 184 Pfam PF01613 Flavin reductase like domain 15 167 1.9E-16 T 09-11-2016 IPR002563 Flavin reductase like domain GO:0010181 CLOSPO_RS17635 ed59eae80b32d270ef8e29342ad082bf 184 SMART SM00903 11 145 2.2E-7 T 09-11-2016 IPR002563 Flavin reductase like domain GO:0010181 CLOSPO_RS17635 ed59eae80b32d270ef8e29342ad082bf 184 Gene3D G3DSA:2.30.110.10 11 172 3.4E-38 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS17635 ed59eae80b32d270ef8e29342ad082bf 184 SUPERFAMILY SSF50475 9 169 1.18E-31 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS17635 ed59eae80b32d270ef8e29342ad082bf 184 PANTHER PTHR30466:SF6 13 184 9.3E-51 T 09-11-2016 CLOSPO_RS17635 ed59eae80b32d270ef8e29342ad082bf 184 PANTHER PTHR30466 13 184 9.3E-51 T 09-11-2016 CLOSPO_RS18240 63e805559ee98521aca117607fa0e090 341 Pfam PF01497 Periplasmic binding protein 77 312 4.8E-26 T 09-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CLOSPO_RS18240 63e805559ee98521aca117607fa0e090 341 SUPERFAMILY SSF53807 64 341 2.28E-44 T 09-11-2016 CLOSPO_RS18240 63e805559ee98521aca117607fa0e090 341 Gene3D G3DSA:3.40.50.1980 202 340 2.2E-29 T 09-11-2016 CLOSPO_RS18240 63e805559ee98521aca117607fa0e090 341 Gene3D G3DSA:3.40.50.1980 70 199 8.6E-9 T 09-11-2016 CLOSPO_RS18240 63e805559ee98521aca117607fa0e090 341 PANTHER PTHR30535 64 338 6.2E-149 T 09-11-2016 CLOSPO_RS18240 63e805559ee98521aca117607fa0e090 341 PANTHER PTHR30535:SF14 64 338 6.2E-149 T 09-11-2016 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 PANTHER PTHR30009:SF11 8 506 0.0 T 09-11-2016 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 491 1.6E-14 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 Pfam PF02378 Phosphotransferase system, EIIC 16 346 6.7E-61 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 Pfam PF00367 phosphotransferase system, EIIB 434 466 6.3E-12 T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 SUPERFAMILY SSF55604 431 505 4.18E-19 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 Gene3D G3DSA:3.30.1360.60 429 506 8.8E-25 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13290 5c960c74281d3c7dbdc9bbfaa9c1803a 507 PANTHER PTHR30009 8 506 0.0 T 09-11-2016 CLOSPO_RS16310 326f887e8a9a324978a2868bc29cce43 170 Hamap MF_01515 UPF0316 protein . 2 170 27.409 T 09-11-2016 IPR022930 Protein of unknown function UPF0316 CLOSPO_RS16310 326f887e8a9a324978a2868bc29cce43 170 PANTHER PTHR40060 1 170 2.5E-72 T 09-11-2016 CLOSPO_RS16310 326f887e8a9a324978a2868bc29cce43 170 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 113 164 1.2E-7 T 09-11-2016 IPR019264 Domain of unknown function DUF2179 CLOSPO_RS13855 7e2d6fee53ad72dad3d1c669809444a8 225 PANTHER PTHR11907 64 221 1.7E-42 T 09-11-2016 CLOSPO_RS13855 7e2d6fee53ad72dad3d1c669809444a8 225 Gene3D G3DSA:3.40.50.2020 59 223 2.8E-28 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS13855 7e2d6fee53ad72dad3d1c669809444a8 225 PANTHER PTHR11907:SF9 64 221 1.7E-42 T 09-11-2016 CLOSPO_RS13855 7e2d6fee53ad72dad3d1c669809444a8 225 SUPERFAMILY SSF53271 70 220 1.44E-24 T 09-11-2016 IPR029057 Phosphoribosyltransferase-like CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 Gene3D G3DSA:3.40.50.880 290 532 1.7E-107 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 528 7.6E-264 T 09-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 Gene3D G3DSA:3.40.50.300 1 286 1.7E-142 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 SUPERFAMILY SSF52317 291 531 8.25E-87 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 Pfam PF00117 Glutamine amidotransferase class-I 303 528 1.4E-62 T 09-11-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 Pfam PF06418 CTP synthase N-terminus 4 268 4.3E-133 T 09-11-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 SUPERFAMILY SSF52540 3 271 1.18E-127 T 09-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 Hamap MF_01227 CTP synthase [pyrG]. 3 533 53.174 T 09-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 CLOSPO_RS14065 c3d219a05f747ed778aca33e6f8ba85c 533 PANTHER PTHR11550 1 528 0.0 T 09-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 CLOSPO_RS18400 05d7a726b01013f1783a14977e248cb6 143 PANTHER PTHR33746:SF2 11 143 1.4E-92 T 09-11-2016 CLOSPO_RS18400 05d7a726b01013f1783a14977e248cb6 143 PANTHER PTHR33746 11 143 1.4E-92 T 09-11-2016 CLOSPO_RS18400 05d7a726b01013f1783a14977e248cb6 143 SUPERFAMILY SSF47240 20 142 4.62E-30 T 09-11-2016 IPR009078 Ferritin-like superfamily CLOSPO_RS18400 05d7a726b01013f1783a14977e248cb6 143 Gene3D G3DSA:1.20.1260.10 18 141 8.7E-34 T 09-11-2016 IPR012347 Ferritin-related CLOSPO_RS18400 05d7a726b01013f1783a14977e248cb6 143 Pfam PF02915 Rubrerythrin 85 142 2.0E-5 T 09-11-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS18400 05d7a726b01013f1783a14977e248cb6 143 Pfam PF02915 Rubrerythrin 28 79 1.4E-7 T 09-11-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CLOSPO_RS13350 d33ef0f40583681eb019410b7c2f99e2 174 Pfam PF01872 RibD C-terminal domain 3 152 7.6E-18 T 09-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CLOSPO_RS13350 d33ef0f40583681eb019410b7c2f99e2 174 Gene3D G3DSA:3.40.430.10 3 172 2.0E-30 T 09-11-2016 IPR024072 Dihydrofolate reductase-like domain CLOSPO_RS13350 d33ef0f40583681eb019410b7c2f99e2 174 PANTHER PTHR38011 3 171 1.8E-14 T 09-11-2016 CLOSPO_RS13350 d33ef0f40583681eb019410b7c2f99e2 174 SUPERFAMILY SSF53597 3 172 5.76E-31 T 09-11-2016 IPR024072 Dihydrofolate reductase-like domain CLOSPO_RS13825 8113d929f3a3ddae1f679c9b8ae09fff 197 Pfam PF12822 Protein of unknown function (DUF3816) 7 186 2.3E-30 T 09-11-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 CLOSPO_RS13825 8113d929f3a3ddae1f679c9b8ae09fff 197 PANTHER PTHR38438 2 197 5.0E-65 T 09-11-2016 CLOSPO_RS13825 8113d929f3a3ddae1f679c9b8ae09fff 197 PIRSF PIRSF037778 2 197 2.3E-51 T 09-11-2016 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CLOSPO_RS13825 8113d929f3a3ddae1f679c9b8ae09fff 197 PANTHER PTHR38438:SF1 2 197 5.0E-65 T 09-11-2016 CLOSPO_RS15680 80e4b79f9c12ab23ce85bef988ea3a3e 79 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 1.6E-23 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS15680 80e4b79f9c12ab23ce85bef988ea3a3e 79 Gene3D G3DSA:1.10.260.40 1 69 6.5E-17 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS15680 80e4b79f9c12ab23ce85bef988ea3a3e 79 SMART SM00530 6 62 1.7E-6 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS15680 80e4b79f9c12ab23ce85bef988ea3a3e 79 PANTHER PTHR37301 2 79 6.2E-37 T 09-11-2016 CLOSPO_RS15680 80e4b79f9c12ab23ce85bef988ea3a3e 79 SUPERFAMILY SSF47413 2 71 4.22E-18 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS15875 23e3b30c19015984fa65dd437526a40c 314 Gene3D G3DSA:3.40.50.1820 2 150 1.1E-67 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS15875 23e3b30c19015984fa65dd437526a40c 314 Gene3D G3DSA:3.40.50.1820 187 313 1.1E-67 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS15875 23e3b30c19015984fa65dd437526a40c 314 Pfam PF12146 Serine aminopeptidase, S33 28 292 2.4E-62 T 09-11-2016 IPR022742 Serine aminopeptidase, S33 CLOSPO_RS15875 23e3b30c19015984fa65dd437526a40c 314 SUPERFAMILY SSF53474 7 307 2.55E-36 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS15875 23e3b30c19015984fa65dd437526a40c 314 PANTHER PTHR11614 6 306 6.2E-58 T 09-11-2016 CLOSPO_RS15875 23e3b30c19015984fa65dd437526a40c 314 PANTHER PTHR11614:SF87 6 306 6.2E-58 T 09-11-2016 CLOSPO_RS14075 18ee4c1a34e6e250e0505adc45a15b35 142 Gene3D G3DSA:2.40.128.20 1 140 6.2E-40 T 09-11-2016 IPR012674 Calycin CLOSPO_RS14075 18ee4c1a34e6e250e0505adc45a15b35 142 Pfam PF09148 Domain of unknown function (DUF1934) 13 135 1.3E-36 T 09-11-2016 IPR015231 Protein of unknown function DUF1934 CLOSPO_RS14075 18ee4c1a34e6e250e0505adc45a15b35 142 PANTHER PTHR41323 1 142 1.1E-41 T 09-11-2016 CLOSPO_RS14075 18ee4c1a34e6e250e0505adc45a15b35 142 SUPERFAMILY SSF50814 3 137 9.02E-30 T 09-11-2016 IPR011038 Calycin-like CLOSPO_RS13515 67d05fdf3cf32877d2f9edd4f2d1f0df 88 Pfam PF08765 Mor transcription activator family 11 81 3.9E-10 T 09-11-2016 IPR014875 Mor transcription activator CLOSPO_RS13515 67d05fdf3cf32877d2f9edd4f2d1f0df 88 SUPERFAMILY SSF46689 10 81 9.56E-15 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS13515 67d05fdf3cf32877d2f9edd4f2d1f0df 88 Gene3D G3DSA:1.10.10.60 51 81 1.3E-6 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS12830 305a9ade6bd7168309daf6a935c89298 471 PANTHER PTHR11819 1 444 7.3E-129 T 09-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS12830 305a9ade6bd7168309daf6a935c89298 471 Pfam PF00474 Sodium:solute symporter family 32 426 1.7E-37 T 09-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CLOSPO_RS12830 305a9ade6bd7168309daf6a935c89298 471 PANTHER PTHR11819:SF7 1 444 7.3E-129 T 09-11-2016 CLOSPO_RS08010 18c0a09838926607b4395711c8028e49 131 PANTHER PTHR18866 1 131 8.4E-79 T 09-11-2016 CLOSPO_RS08010 18c0a09838926607b4395711c8028e49 131 Pfam PF02436 Conserved carboxylase domain 7 130 1.1E-55 T 09-11-2016 IPR003379 Carboxylase, conserved domain CLOSPO_RS08010 18c0a09838926607b4395711c8028e49 131 PANTHER PTHR18866:SF103 1 131 8.4E-79 T 09-11-2016 CLOSPO_RS08010 18c0a09838926607b4395711c8028e49 131 SUPERFAMILY SSF89000 12 131 7.85E-44 T 09-11-2016 CLOSPO_RS13200 9e0dd5907b170e6097c5988ea810f10a 212 Gene3D G3DSA:3.40.50.720 1 211 1.3E-38 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13200 9e0dd5907b170e6097c5988ea810f10a 212 PANTHER PTHR15020:SF29 1 212 1.0E-83 T 09-11-2016 CLOSPO_RS13200 9e0dd5907b170e6097c5988ea810f10a 212 Pfam PF13460 NAD(P)H-binding 7 200 2.6E-31 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13200 9e0dd5907b170e6097c5988ea810f10a 212 SUPERFAMILY SSF51735 1 210 3.5E-35 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS13200 9e0dd5907b170e6097c5988ea810f10a 212 PANTHER PTHR15020 1 212 1.0E-83 T 09-11-2016 CLOSPO_RS06125 c3fbfac0f9f128159c954e7828bdb521 77 SUPERFAMILY SSF55103 1 77 6.1E-8 T 09-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CLOSPO_RS06125 c3fbfac0f9f128159c954e7828bdb521 77 Pfam PF02913 FAD linked oxidases, C-terminal domain 1 77 1.4E-11 T 09-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 Gene3D G3DSA:3.30.1360.60 447 524 1.4E-24 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 PANTHER PTHR30009:SF5 7 523 0.0 T 09-11-2016 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 SUPERFAMILY SSF55604 449 523 9.68E-20 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 411 508 1.2E-16 T 09-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 PANTHER PTHR30009 7 523 0.0 T 09-11-2016 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 Pfam PF00367 phosphotransferase system, EIIB 453 483 8.1E-14 T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 461 478 - T 09-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CLOSPO_RS13185 654d8faebd7467be9c4689d8a623f7fe 527 Pfam PF02378 Phosphotransferase system, EIIC 14 351 1.7E-66 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS18505 0751e84a8eda1a5b8e1e8e77215f22f6 181 SUPERFAMILY SSF102198 26 158 5.23E-22 T 09-11-2016 CLOSPO_RS18505 0751e84a8eda1a5b8e1e8e77215f22f6 181 Gene3D G3DSA:3.50.30.50 27 171 1.6E-18 T 09-11-2016 CLOSPO_RS18505 0751e84a8eda1a5b8e1e8e77215f22f6 181 Pfam PF04199 Putative cyclase 21 125 7.7E-10 T 09-11-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 CLOSPO_RS14435 4ca83389c46fc7a478884e85b4afedff 67 Pfam PF00403 Heavy-metal-associated domain 17 65 8.4E-7 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS14435 4ca83389c46fc7a478884e85b4afedff 67 Gene3D G3DSA:3.30.70.100 2 66 6.6E-11 T 09-11-2016 CLOSPO_RS14435 4ca83389c46fc7a478884e85b4afedff 67 SUPERFAMILY SSF55008 1 66 5.89E-12 T 09-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOSPO_RS12860 450d9ce69fa1f384308e69824e87d75d 422 Pfam PF00999 Sodium/hydrogen exchanger family 18 398 4.8E-53 T 09-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CLOSPO_RS12860 450d9ce69fa1f384308e69824e87d75d 422 PANTHER PTHR32507 1 422 6.8E-141 T 09-11-2016 CLOSPO_RS12860 450d9ce69fa1f384308e69824e87d75d 422 PANTHER PTHR32507:SF0 1 422 6.8E-141 T 09-11-2016 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 PANTHER PTHR10458 1 161 1.2E-44 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 PRINTS PR01576 Peptide deformylase signature 39 68 3.1E-12 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 PRINTS PR01576 Peptide deformylase signature 124 153 3.1E-12 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 PRINTS PR01576 Peptide deformylase signature 93 104 3.1E-12 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 PRINTS PR01576 Peptide deformylase signature 105 123 3.1E-12 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 Hamap MF_00163 Peptide deformylase [def]. 2 166 19.091 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 Gene3D G3DSA:3.90.45.10 5 162 1.0E-39 T 09-11-2016 IPR023635 Peptide deformylase CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 Pfam PF01327 Polypeptide deformylase 4 155 1.4E-37 T 09-11-2016 IPR023635 Peptide deformylase CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 SUPERFAMILY SSF56420 4 162 1.31E-41 T 09-11-2016 IPR023635 Peptide deformylase CLOSPO_RS17730 be2ab317cef51580944d169246402b0b 166 PIRSF PIRSF004749 1 164 4.7E-30 T 09-11-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 CLOSPO_RS16080 ffec2d189882f46b4a8eb0319c55a4c7 302 Pfam PF00561 alpha/beta hydrolase fold 84 207 3.5E-9 T 09-11-2016 IPR000073 Alpha/beta hydrolase fold-1 CLOSPO_RS16080 ffec2d189882f46b4a8eb0319c55a4c7 302 Gene3D G3DSA:3.40.50.1820 56 301 1.3E-45 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS16080 ffec2d189882f46b4a8eb0319c55a4c7 302 SUPERFAMILY SSF53474 48 299 1.35E-43 T 09-11-2016 IPR029058 Alpha/Beta hydrolase fold CLOSPO_RS16080 ffec2d189882f46b4a8eb0319c55a4c7 302 PANTHER PTHR12277 51 300 3.5E-48 T 09-11-2016 CLOSPO_RS15685 90a4130ee848120f32540a09103c1cd6 153 Pfam PF11188 Protein of unknown function (DUF2975) 46 153 2.2E-15 T 09-11-2016 IPR021354 Protein of unknown function DUF2975 CLOSPO_RS12790 8d80f955a2005b3bdedc4bffb831b0d3 178 PANTHER PTHR41780 1 178 2.6E-58 T 09-11-2016 CLOSPO_RS12790 8d80f955a2005b3bdedc4bffb831b0d3 178 PIRSF PIRSF027391 3 178 1.5E-58 T 09-11-2016 IPR014535 Predicted heptaprenyl diphosphate synthase, component I CLOSPO_RS12790 8d80f955a2005b3bdedc4bffb831b0d3 178 PANTHER PTHR41780:SF1 1 178 2.6E-58 T 09-11-2016 CLOSPO_RS12790 8d80f955a2005b3bdedc4bffb831b0d3 178 Pfam PF07456 Heptaprenyl diphosphate synthase component I 17 160 1.4E-49 T 09-11-2016 IPR010898 Heptaprenyl diphosphate synthase component I CLOSPO_RS13140 3d6a8dabefa411eb7e2fbe577159d064 322 SUPERFAMILY SSF53448 6 196 6.19E-35 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS13140 3d6a8dabefa411eb7e2fbe577159d064 322 Gene3D G3DSA:3.90.550.10 7 138 5.6E-28 T 09-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases CLOSPO_RS13140 3d6a8dabefa411eb7e2fbe577159d064 322 PANTHER PTHR10859:SF86 3 321 2.9E-171 T 09-11-2016 CLOSPO_RS13140 3d6a8dabefa411eb7e2fbe577159d064 322 Pfam PF00535 Glycosyl transferase family 2 8 170 7.5E-37 T 09-11-2016 IPR001173 Glycosyltransferase 2-like CLOSPO_RS13140 3d6a8dabefa411eb7e2fbe577159d064 322 PANTHER PTHR10859 3 321 2.9E-171 T 09-11-2016 CLOSPO_RS18000 d9c6c3800895c1298bb73617e221573c 228 Pfam PF02361 Cobalt transport protein 19 194 1.3E-16 T 09-11-2016 IPR003339 ABC/ECF transporter, transmembrane component CLOSPO_RS18000 d9c6c3800895c1298bb73617e221573c 228 PANTHER PTHR34857 3 227 6.6E-63 T 09-11-2016 CLOSPO_RS18000 d9c6c3800895c1298bb73617e221573c 228 PANTHER PTHR34857:SF1 3 227 6.6E-63 T 09-11-2016 CLOSPO_RS17090 44c5207b80e238438d9f6ffdfe3c9283 87 PANTHER PTHR37812 1 86 1.4E-17 T 09-11-2016 CLOSPO_RS17090 44c5207b80e238438d9f6ffdfe3c9283 87 SUPERFAMILY SSF46689 1 86 2.33E-12 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17090 44c5207b80e238438d9f6ffdfe3c9283 87 PANTHER PTHR37812:SF1 1 86 1.4E-17 T 09-11-2016 CLOSPO_RS17090 44c5207b80e238438d9f6ffdfe3c9283 87 Gene3D G3DSA:1.10.10.60 51 85 7.4E-5 T 09-11-2016 IPR009057 Homeodomain-like GO:0003677 CLOSPO_RS17420 15c329a6ec95a279ca8956cfa27abd53 172 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 12 167 6.3E-22 T 09-11-2016 IPR013343 CRISPR-associated protein Cas4 CLOSPO_RS17420 15c329a6ec95a279ca8956cfa27abd53 172 PANTHER PTHR37168:SF1 1 168 2.8E-56 T 09-11-2016 CLOSPO_RS17420 15c329a6ec95a279ca8956cfa27abd53 172 PANTHER PTHR37168 1 168 2.8E-56 T 09-11-2016 CLOSPO_RS17420 15c329a6ec95a279ca8956cfa27abd53 172 Pfam PF01930 Domain of unknown function DUF83 11 167 1.9E-49 T 09-11-2016 IPR022765 Dna2/Cas4, domain of unknown function DUF83 CLOSPO_RS11625 754b40a882bb94a8f3e96a7fa1e5bf91 201 Gene3D G3DSA:3.40.50.620 1 101 9.3E-12 T 09-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOSPO_RS11625 754b40a882bb94a8f3e96a7fa1e5bf91 201 SUPERFAMILY SSF52374 3 100 5.63E-9 T 09-11-2016 CLOSPO_RS17995 6468d076753851961e359161ca18e24c 99 Pfam PF02553 Cobalt transport protein component CbiN 5 73 3.4E-30 T 09-11-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 CLOSPO_RS17995 6468d076753851961e359161ca18e24c 99 PANTHER PTHR38662 1 99 6.4E-43 T 09-11-2016 CLOSPO_RS17995 6468d076753851961e359161ca18e24c 99 TIGRFAM TIGR01165 cbiN: cobalt transport protein 2 87 6.2E-33 T 09-11-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 CLOSPO_RS17995 6468d076753851961e359161ca18e24c 99 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 99 42.311 T 09-11-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 Gene3D G3DSA:3.60.21.10 378 482 3.8E-6 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 Gene3D G3DSA:3.60.21.10 518 575 3.8E-6 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 Gene3D G3DSA:3.60.21.10 202 242 3.8E-6 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 Gene3D G3DSA:3.60.21.10 44 77 3.8E-6 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 17 655 0.0 T 09-11-2016 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 PIRSF PIRSF000906 11 657 0.0 T 09-11-2016 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 15 656 40.565 T 09-11-2016 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 CLOSPO_RS15930 f5db05415e4b23850e2a129fe81d5078 668 SUPERFAMILY SSF56300 195 250 2.46E-5 T 09-11-2016 IPR029052 Metallo-dependent phosphatase-like CLOSPO_RS14960 51e60755ba449743399e6ff727faae53 581 TIGRFAM TIGR04480 D_pro_red_PrdA: D-proline reductase (dithiol), PrdA proprotein 4 575 7.8E-284 T 09-11-2016 IPR031002 D-proline reductase, PrdA proprotein GO:0050002|GO:0055114 KEGG: 00330+1.21.4.1 CLOSPO_RS14960 51e60755ba449743399e6ff727faae53 581 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 159 500 2.6E-29 T 09-11-2016 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOSPO_RS12940 a156b9afdb4cab2ed6ebec29e17e9d38 197 Pfam PF12672 Protein of unknown function (DUF3793) 27 195 9.1E-41 T 09-11-2016 IPR024523 Protein of unknown function DUF3793 CLOSPO_RS13995 597be3f385ce267ac01f08c2e75ba9a8 162 PANTHER PTHR11086 1 133 2.3E-28 T 09-11-2016 IPR015517 Deoxycytidylate deaminase-related CLOSPO_RS13995 597be3f385ce267ac01f08c2e75ba9a8 162 Gene3D G3DSA:3.40.140.10 7 142 3.2E-28 T 09-11-2016 CLOSPO_RS13995 597be3f385ce267ac01f08c2e75ba9a8 162 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 79 124 - T 09-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CLOSPO_RS13995 597be3f385ce267ac01f08c2e75ba9a8 162 PIRSF PIRSF006019 1 161 2.7E-35 T 09-11-2016 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210 CLOSPO_RS13995 597be3f385ce267ac01f08c2e75ba9a8 162 SUPERFAMILY SSF53927 8 140 9.37E-24 T 09-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 CLOSPO_RS13995 597be3f385ce267ac01f08c2e75ba9a8 162 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 134 1.7E-17 T 09-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CLOSPO_RS18830 76b75e8499ee1fb7636eb037f76ba5de 233 Pfam PF02517 CAAX protease self-immunity 121 220 6.7E-14 T 09-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 CLOSPO_RS14645 474cf8af7ccd5ef8a9fc5b4ebe8d285a 382 PANTHER PTHR30548:SF6 1 382 9.0E-229 T 09-11-2016 CLOSPO_RS14645 474cf8af7ccd5ef8a9fc5b4ebe8d285a 382 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 37 382 9.0E-86 T 09-11-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit CLOSPO_RS14645 474cf8af7ccd5ef8a9fc5b4ebe8d285a 382 PANTHER PTHR30548 1 382 9.0E-229 T 09-11-2016 CLOSPO_RS17050 f787c0a83bddbb8512f944f96035a5d0 208 SUPERFAMILY SSF52317 5 177 6.22E-28 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS17050 f787c0a83bddbb8512f944f96035a5d0 208 Pfam PF01965 DJ-1/PfpI family 5 167 2.8E-22 T 09-11-2016 IPR002818 DJ-1/PfpI CLOSPO_RS17050 f787c0a83bddbb8512f944f96035a5d0 208 Gene3D G3DSA:3.40.50.880 5 177 1.4E-28 T 09-11-2016 IPR029062 Class I glutamine amidotransferase-like CLOSPO_RS12845 dfda7c03738b9b31609cdd908416b425 224 Pfam PF14378 PAP2 superfamily 51 190 1.7E-11 T 09-11-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CLOSPO_RS12845 dfda7c03738b9b31609cdd908416b425 224 SUPERFAMILY SSF48317 11 194 2.35E-8 T 09-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOSPO_RS18135 b718e3a05fe5a90d7765944819c3ef5e 114 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 80 108 3.6E-5 T 09-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 CLOSPO_RS18135 b718e3a05fe5a90d7765944819c3ef5e 114 Gene3D G3DSA:3.30.1390.10 70 108 1.7E-5 T 09-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CLOSPO_RS14245 00deda1f296f996164e354fb407fd5f9 225 Pfam PF06304 Protein of unknown function (DUF1048) 17 90 1.3E-8 T 09-11-2016 IPR008316 Uncharacterised conserved protein UCP029876 CLOSPO_RS14245 00deda1f296f996164e354fb407fd5f9 225 PANTHER PTHR41307 2 224 2.8E-57 T 09-11-2016 CLOSPO_RS14245 00deda1f296f996164e354fb407fd5f9 225 SUPERFAMILY SSF158560 1 100 1.16E-26 T 09-11-2016 CLOSPO_RS14245 00deda1f296f996164e354fb407fd5f9 225 Gene3D G3DSA:1.10.1900.10 24 87 1.2E-10 T 09-11-2016 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 CLOSPO_RS17885 a16649def40712947eff1aaeadd212e5 341 PANTHER PTHR13812 73 329 1.9E-45 T 09-11-2016 CLOSPO_RS17885 a16649def40712947eff1aaeadd212e5 341 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 17 318 3.9E-91 T 09-11-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin CLOSPO_RS17885 a16649def40712947eff1aaeadd212e5 341 SUPERFAMILY SSF51735 5 340 4.42E-88 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS17885 a16649def40712947eff1aaeadd212e5 341 Gene3D G3DSA:3.30.1780.10 6 143 2.4E-35 T 09-11-2016 IPR023401 Ornithine cyclodeaminase, N-terminal CLOSPO_RS17885 a16649def40712947eff1aaeadd212e5 341 PANTHER PTHR13812:SF19 73 329 1.9E-45 T 09-11-2016 CLOSPO_RS17885 a16649def40712947eff1aaeadd212e5 341 Gene3D G3DSA:3.40.50.720 144 299 3.4E-48 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18720 b5eb7ca9e43e047814c3680cb15700d6 226 PANTHER PTHR33514 8 226 1.7E-23 T 09-11-2016 CLOSPO_RS18720 b5eb7ca9e43e047814c3680cb15700d6 226 Pfam PF02361 Cobalt transport protein 8 184 8.5E-11 T 09-11-2016 IPR003339 ABC/ECF transporter, transmembrane component CLOSPO_RS15765 d1fb734f66677158fdead7a02e2dbf67 360 TIGRFAM TIGR03603 cyclo_dehy_ocin: thiazole/oxazole-forming peptide maturase, SagC family component 30 356 1.2E-119 T 09-11-2016 IPR019892 Thiazole/oxazole-forming peptide maturase, SagC family component CLOSPO_RS15765 d1fb734f66677158fdead7a02e2dbf67 360 SUPERFAMILY SSF69572 171 335 7.19E-8 T 09-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CLOSPO_RS15765 d1fb734f66677158fdead7a02e2dbf67 360 Gene3D G3DSA:3.40.50.720 166 334 5.8E-5 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS12945 2ecb84bbd1426d276a89d6d23a7f0f52 95 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 2 90 1.8E-17 T 09-11-2016 IPR016772 Uncharacterised conserved protein UCP020408 CLOSPO_RS12945 2ecb84bbd1426d276a89d6d23a7f0f52 95 PIRSF PIRSF020408 1 95 5.0E-33 T 09-11-2016 IPR016772 Uncharacterised conserved protein UCP020408 CLOSPO_RS16825 6174bfdc7c0ffb5274154533cd940378 225 PANTHER PTHR37171 1 225 1.9E-33 T 09-11-2016 CLOSPO_RS16825 6174bfdc7c0ffb5274154533cd940378 225 PANTHER PTHR37171:SF1 1 225 1.9E-33 T 09-11-2016 CLOSPO_RS16825 6174bfdc7c0ffb5274154533cd940378 225 SUPERFAMILY SSF56112 49 188 1.1E-10 T 09-11-2016 IPR011009 Protein kinase-like domain CLOSPO_RS15505 250905f1dac96640821cfc4495c8a7f4 268 SUPERFAMILY SSF54427 88 255 4.09E-26 T 09-11-2016 IPR032710 NTF2-like domain CLOSPO_RS15505 250905f1dac96640821cfc4495c8a7f4 268 Pfam PF04280 Tim44-like domain 109 241 4.1E-10 T 09-11-2016 IPR007379 Tim44-like domain CLOSPO_RS15505 250905f1dac96640821cfc4495c8a7f4 268 SMART SM00978 108 252 5.5E-29 T 09-11-2016 IPR007379 Tim44-like domain CLOSPO_RS18795 68327b95dd17f79e5ce15c64cfe7a286 320 Gene3D G3DSA:3.40.50.720 5 189 1.5E-40 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18795 68327b95dd17f79e5ce15c64cfe7a286 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 242 1.6E-43 T 09-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CLOSPO_RS18795 68327b95dd17f79e5ce15c64cfe7a286 320 SUPERFAMILY SSF51735 4 314 1.41E-64 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18795 68327b95dd17f79e5ce15c64cfe7a286 320 Gene3D G3DSA:3.90.25.10 190 317 8.1E-22 T 09-11-2016 CLOSPO_RS18795 68327b95dd17f79e5ce15c64cfe7a286 320 PANTHER PTHR10366 4 320 8.4E-61 T 09-11-2016 CLOSPO_RS16025 5c405db0fcfa8567d7aaad1c1e8ec058 141 SUPERFAMILY SSF158397 26 140 2.62E-35 T 09-11-2016 CLOSPO_RS16025 5c405db0fcfa8567d7aaad1c1e8ec058 141 Gene3D G3DSA:1.20.120.490 26 140 4.8E-37 T 09-11-2016 IPR024042 Hypothetical protein TM1646-like domain CLOSPO_RS16025 5c405db0fcfa8567d7aaad1c1e8ec058 141 Pfam PF03885 Protein of unknown function (DUF327) 13 140 2.3E-39 T 09-11-2016 IPR005585 Protein of unknown function DUF327 CLOSPO_RS02340 244066febcde075e576c3c68fa5f5c5f 319 PANTHER PTHR41324:SF1 9 319 5.1E-61 T 09-11-2016 CLOSPO_RS02340 244066febcde075e576c3c68fa5f5c5f 319 Pfam PF09991 Predicted membrane protein (DUF2232) 27 319 1.2E-67 T 09-11-2016 IPR018710 Protein of unknown function DUF2232 CLOSPO_RS02340 244066febcde075e576c3c68fa5f5c5f 319 PANTHER PTHR41324 9 319 5.1E-61 T 09-11-2016 CLOSPO_RS15775 bb4665fdc0cb95c7019e9ab679bb9ca7 212 Pfam PF02517 CAAX protease self-immunity 118 206 9.1E-10 T 09-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 CLOSPO_RS13715 cf40f8815d40f3776f16a8247f6ee26a 173 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 09-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOSPO_RS13715 cf40f8815d40f3776f16a8247f6ee26a 173 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 72 2.5E-13 T 09-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOSPO_RS13715 cf40f8815d40f3776f16a8247f6ee26a 173 PANTHER PTHR15362:SF5 9 168 1.3E-34 T 09-11-2016 CLOSPO_RS13715 cf40f8815d40f3776f16a8247f6ee26a 173 PANTHER PTHR15362 9 168 1.3E-34 T 09-11-2016 CLOSPO_RS13715 cf40f8815d40f3776f16a8247f6ee26a 173 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 14 169 2.5E-36 T 09-11-2016 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 PANTHER PTHR20857:SF15 1 202 4.8E-85 T 09-11-2016 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 PANTHER PTHR20857 1 202 4.8E-85 T 09-11-2016 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 Gene3D G3DSA:3.20.20.70 3 201 7.4E-76 T 09-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 SUPERFAMILY SSF51391 5 201 3.14E-65 T 09-11-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 200 4.6E-69 T 09-11-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 Pfam PF02581 Thiamine monophosphate synthase/TENI 7 188 2.8E-68 T 09-11-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS15580 0d0f0329d29594143a95b9ea156c8b43 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 4 205 27.584 T 09-11-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 CLOSPO_RS06965 b87d91273ac93f3e8ff8953ec62e2d48 118 SUPERFAMILY SSF81923 24 91 3.92E-13 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS06965 b87d91273ac93f3e8ff8953ec62e2d48 118 Gene3D G3DSA:1.10.1780.10 2 84 3.4E-18 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS06965 b87d91273ac93f3e8ff8953ec62e2d48 118 PANTHER PTHR11638 1 118 2.5E-25 T 09-11-2016 CLOSPO_RS06965 b87d91273ac93f3e8ff8953ec62e2d48 118 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 38 84 2.2E-16 T 09-11-2016 IPR004176 Clp, N-terminal GO:0019538 CLOSPO_RS06965 b87d91273ac93f3e8ff8953ec62e2d48 118 PANTHER PTHR11638:SF18 1 118 2.5E-25 T 09-11-2016 CLOSPO_RS17980 9cb74314c3466e510c1f4627c3a99224 320 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 12 303 1.5E-70 T 09-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 CLOSPO_RS17980 9cb74314c3466e510c1f4627c3a99224 320 Pfam PF03186 CobD/Cbib protein 12 302 5.8E-100 T 09-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 CLOSPO_RS17980 9cb74314c3466e510c1f4627c3a99224 320 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 320 88.733 T 09-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 CLOSPO_RS17980 9cb74314c3466e510c1f4627c3a99224 320 PANTHER PTHR34308:SF1 1 317 5.7E-112 T 09-11-2016 CLOSPO_RS17980 9cb74314c3466e510c1f4627c3a99224 320 PANTHER PTHR34308 1 317 5.7E-112 T 09-11-2016 CLOSPO_RS17855 481304355764785e1c09bc426f3a69f6 112 Pfam PF12788 YmaF family 8 104 8.8E-39 T 09-11-2016 IPR024307 YmaF CLOSPO_RS18335 baff579ce2330aa07ce35d89a51b7dd8 110 SUPERFAMILY SSF159894 6 97 2.62E-22 T 09-11-2016 CLOSPO_RS18335 baff579ce2330aa07ce35d89a51b7dd8 110 Gene3D G3DSA:3.30.1460.30 6 66 1.3E-15 T 09-11-2016 IPR007076 TfoX, N-terminal CLOSPO_RS18335 baff579ce2330aa07ce35d89a51b7dd8 110 Pfam PF04993 TfoX N-terminal domain 14 61 1.6E-10 T 09-11-2016 IPR007076 TfoX, N-terminal CLOSPO_RS11305 d90a233204f7cf2bec54c93ed0e44519 228 Pfam PF13440 Polysaccharide biosynthesis protein 4 214 4.0E-11 T 09-11-2016 CLOSPO_RS17160 6de557caf09fbcbea12087200287aa91 73 Pfam PF07872 Protein of unknown function (DUF1659) 8 51 2.7E-13 T 09-11-2016 IPR012454 Protein of unknown function DUF1659 CLOSPO_RS17155 48252f850cf1daba9d469ca61ae3da1d 59 Pfam PF12841 YvrJ protein family 8 42 1.4E-18 T 09-11-2016 IPR024419 Protein of unknown function YvrJ CLOSPO_RS12695 e3051534d3d0ddb5716b82d319546e46 274 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 149 272 2.2E-38 T 09-11-2016 IPR030910 SLAP domain, Bacillus-type CLOSPO_RS12695 e3051534d3d0ddb5716b82d319546e46 274 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 16 139 8.3E-38 T 09-11-2016 IPR030910 SLAP domain, Bacillus-type CLOSPO_RS16710 fb18dc5a7e4dcc88e2ff686972ca9760 252 Pfam PF14335 Domain of unknown function (DUF4391) 9 241 2.5E-64 T 09-11-2016 IPR025503 Protein of unknown function DUF4391 CLOSPO_RS15655 8e1556745b3a12e35264a11409d1ca93 289 PANTHER PTHR30373 1 245 3.0E-77 T 09-11-2016 CLOSPO_RS15655 8e1556745b3a12e35264a11409d1ca93 289 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 45 164 1.6E-32 T 09-11-2016 IPR007621 TPM domain CLOSPO_RS15655 8e1556745b3a12e35264a11409d1ca93 289 PANTHER PTHR30373:SF2 1 245 3.0E-77 T 09-11-2016 CLOSPO_RS13020 98b8e3af300ffcb8cf79012f61c33ac0 225 Pfam PF04647 Accessory gene regulator B 8 197 1.6E-41 T 09-11-2016 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CLOSPO_RS13020 98b8e3af300ffcb8cf79012f61c33ac0 225 SMART SM00793 6 206 2.9E-21 T 09-11-2016 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CLOSPO_RS13475 3e9134ac88d1f6fdf5e7731a4c32a145 67 Pfam PF13783 Domain of unknown function (DUF4177) 3 66 7.4E-7 T 09-11-2016 IPR025234 Protein of unknown function DUF4177 CLOSPO_RS16435 2d3261f8e0e3e55e3f9d10eca4b8b877 372 Pfam PF13303 Phosphotransferase system, EIIC 29 328 1.3E-58 T 09-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOSPO_RS16435 2d3261f8e0e3e55e3f9d10eca4b8b877 372 PANTHER PTHR40063 2 351 8.9E-105 T 09-11-2016 CLOSPO_RS14975 1b902cf6bd099a3a175f9ebaefaf14c3 156 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 6 98 4.2E-9 T 09-11-2016 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOSPO_RS16545 ff1644b61cc5a073d3098fc8dfd4c2ea 159 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 157 3.8E-15 T 09-11-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CLOSPO_RS16545 ff1644b61cc5a073d3098fc8dfd4c2ea 159 SUPERFAMILY SSF50475 1 158 7.66E-40 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS16545 ff1644b61cc5a073d3098fc8dfd4c2ea 159 PANTHER PTHR34071 1 158 3.0E-51 T 09-11-2016 CLOSPO_RS16545 ff1644b61cc5a073d3098fc8dfd4c2ea 159 Gene3D G3DSA:2.30.110.10 1 158 1.4E-46 T 09-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 CLOSPO_RS01420 b944c9ed63a2ee9dd212c4adb4494a26 207 Pfam PF04245 37-kD nucleoid-associated bacterial protein 5 205 5.2E-47 T 09-11-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 CLOSPO_RS18065 3e6397dcfea84d581a60aae22283c95a 233 Gene3D G3DSA:1.10.3290.10 9 219 4.1E-49 T 09-11-2016 IPR003812 Fido domain CLOSPO_RS18065 3e6397dcfea84d581a60aae22283c95a 233 SUPERFAMILY SSF140931 59 220 1.44E-36 T 09-11-2016 IPR003812 Fido domain CLOSPO_RS18065 3e6397dcfea84d581a60aae22283c95a 233 Pfam PF02661 Fic/DOC family 83 180 2.3E-19 T 09-11-2016 IPR003812 Fido domain CLOSPO_RS18065 3e6397dcfea84d581a60aae22283c95a 233 PANTHER PTHR13504:SF29 5 217 2.1E-56 T 09-11-2016 CLOSPO_RS18065 3e6397dcfea84d581a60aae22283c95a 233 PANTHER PTHR13504 5 217 2.1E-56 T 09-11-2016 CLOSPO_RS06235 3e7b157f1b358c90a2d13f511e83eed8 307 PANTHER PTHR11649 1 19 2.5E-82 T 09-11-2016 CLOSPO_RS06235 3e7b157f1b358c90a2d13f511e83eed8 307 Pfam PF07670 Nucleoside recognition 228 306 4.7E-9 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS06235 3e7b157f1b358c90a2d13f511e83eed8 307 PANTHER PTHR11649 137 307 2.5E-82 T 09-11-2016 CLOSPO_RS06235 3e7b157f1b358c90a2d13f511e83eed8 307 PANTHER PTHR11649:SF37 1 19 2.5E-82 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS06235 3e7b157f1b358c90a2d13f511e83eed8 307 PANTHER PTHR11649:SF37 137 307 2.5E-82 T 09-11-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOSPO_RS14085 26dc1043a4f4fa5bbd268b7c52d8f73d 456 Pfam PF14620 YpeB sporulation 17 378 4.1E-127 T 09-11-2016 IPR014239 Spore germination YpeB GO:0009847 CLOSPO_RS14085 26dc1043a4f4fa5bbd268b7c52d8f73d 456 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 7 446 1.1E-158 T 09-11-2016 IPR014239 Spore germination YpeB GO:0009847 CLOSPO_RS14085 26dc1043a4f4fa5bbd268b7c52d8f73d 456 Pfam PF03413 Peptidase propeptide and YPEB domain 383 438 8.2E-5 T 09-11-2016 IPR025711 PepSY domain CLOSPO_RS12980 4e241bc6565a57dcee55ba29164d54ae 44 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 8 44 8.0E-14 T 09-11-2016 IPR009229 Staphylococcal AgrD CLOSPO_RS13050 0bc04676cabfad9ef94fb5f525756576 231 Pfam PF04172 LrgB-like family 16 228 1.9E-78 T 09-11-2016 IPR007300 CidB/LrgB family CLOSPO_RS13050 0bc04676cabfad9ef94fb5f525756576 231 PANTHER PTHR30249 1 231 4.9E-109 T 09-11-2016 CLOSPO_RS13050 0bc04676cabfad9ef94fb5f525756576 231 PANTHER PTHR30249:SF5 1 231 4.9E-109 T 09-11-2016 CLOSPO_RS16225 4330626d868e05ad2ed6a62ce8ddf011 41 TIGRFAM TIGR04333 Clo7Bot_mod_Cys: Cys-rich peptide, Clo7bot family 1 33 3.2E-16 T 09-11-2016 IPR027601 Cys-rich peptide, Clo7bot family CLOSPO_RS14375 8606a152494b3b8043adeca971dfcd6a 191 PANTHER PTHR35793:SF1 2 190 9.2E-112 T 09-11-2016 CLOSPO_RS14375 8606a152494b3b8043adeca971dfcd6a 191 Pfam PF07670 Nucleoside recognition 42 150 2.9E-13 T 09-11-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 CLOSPO_RS14375 8606a152494b3b8043adeca971dfcd6a 191 PANTHER PTHR35793 2 190 9.2E-112 T 09-11-2016 CLOSPO_RS17620 01388f661fde49750d9edcea04d58d6d 357 Pfam PF03845 Spore germination protein 9 320 1.5E-52 T 09-11-2016 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CLOSPO_RS17620 01388f661fde49750d9edcea04d58d6d 357 PANTHER PTHR34975 1 357 3.3E-143 T 09-11-2016 CLOSPO_RS17620 01388f661fde49750d9edcea04d58d6d 357 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 355 1.5E-88 T 09-11-2016 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CLOSPO_RS17620 01388f661fde49750d9edcea04d58d6d 357 PANTHER PTHR34975:SF2 1 357 3.3E-143 T 09-11-2016 CLOSPO_RS18555 0d577da10108603af64e947ec4dfb9a2 159 Pfam PF12724 Flavodoxin domain 4 139 2.7E-30 T 09-11-2016 IPR026816 Flavodoxin domain CLOSPO_RS18555 0d577da10108603af64e947ec4dfb9a2 159 Gene3D G3DSA:3.40.50.360 1 92 5.3E-14 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS18555 0d577da10108603af64e947ec4dfb9a2 159 SUPERFAMILY SSF52218 1 153 1.2E-20 T 09-11-2016 IPR029039 Flavoprotein-like domain CLOSPO_RS18555 0d577da10108603af64e947ec4dfb9a2 159 PANTHER PTHR38030 1 156 2.9E-100 T 09-11-2016 CLOSPO_RS18555 0d577da10108603af64e947ec4dfb9a2 159 PANTHER PTHR38030:SF1 1 156 2.9E-100 T 09-11-2016 CLOSPO_RS17185 415d45c79ff7cd3d8a4054d106be257b 123 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 1 123 1.2E-47 T 09-11-2016 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 CLOSPO_RS18610 1d364346d92ac160a0439a4c5b3506bc 75 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 3 70 9.2E-29 T 09-11-2016 IPR017524 Small acid-soluble spore protein, thioredoxin-like CLOSPO_RS18610 1d364346d92ac160a0439a4c5b3506bc 75 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 75 29.181 T 09-11-2016 IPR017524 Small acid-soluble spore protein, thioredoxin-like CLOSPO_RS13435 8e26c32ede10240d5ffbb3dff0527a9f 251 Pfam PF12730 ABC-2 family transporter protein 4 178 2.5E-9 T 09-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 CLOSPO_RS00475 a531a5b80cc64dd490c8898b5663fd00 111 PANTHER PTHR40032 1 111 6.0E-52 T 09-11-2016 CLOSPO_RS00475 a531a5b80cc64dd490c8898b5663fd00 111 PANTHER PTHR40032:SF1 1 111 6.0E-52 T 09-11-2016 CLOSPO_RS15210 81a9d2fe45ae1443ec5c9a70eac3a251 132 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 13 90 1.7E-16 T 09-11-2016 IPR019074 Spore cortex biosynthesis protein, YabQ-like CLOSPO_RS15210 81a9d2fe45ae1443ec5c9a70eac3a251 132 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 4 120 1.9E-37 T 09-11-2016 IPR014242 Spore cortex biosynthesis protein, YabQ CLOSPO_RS16570 cc44522bc0ae5478b0bb5b7c390e64b7 65 TIGRFAM TIGR04067 oc_CLOSPO_01332: putative bacteriocin precursor, CLOSPO_01332 family 1 59 2.4E-36 T 09-11-2016 IPR023964 Bacteriocin precursor, CLOSPO-01332, putative CLOSPO_RS17840 96b8a49aed7d63eef16a4c445dee99ec 195 Gene3D G3DSA:3.30.460.10 16 187 1.1E-49 T 09-11-2016 CLOSPO_RS17840 96b8a49aed7d63eef16a4c445dee99ec 195 Pfam PF04229 GrpB protein 18 180 4.6E-41 T 09-11-2016 IPR007344 GrpB/Dephospho-CoA kinase CLOSPO_RS17840 96b8a49aed7d63eef16a4c445dee99ec 195 SUPERFAMILY SSF81301 21 186 2.88E-42 T 09-11-2016 CLOSPO_RS17840 96b8a49aed7d63eef16a4c445dee99ec 195 PANTHER PTHR34822 2 191 3.8E-47 T 09-11-2016 CLOSPO_RS18430 496a4c55657903c848f21e73f80e3b9b 71 Pfam PF11211 Protein of unknown function (DUF2997) 5 52 5.8E-21 T 09-11-2016 IPR021375 Protein of unknown function DUF2997 CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 SUPERFAMILY SSF53383 3 382 6.32E-92 T 09-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 3 380 1.0E-150 T 09-11-2016 IPR010969 Cysteine desulfurase-related, unknown function CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 Gene3D G3DSA:3.40.640.10 15 258 7.5E-68 T 09-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 Gene3D G3DSA:3.90.1150.10 259 379 2.1E-16 T 09-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 PANTHER PTHR11601 1 384 4.2E-194 T 09-11-2016 CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 PIRSF PIRSF005572 1 384 3.0E-52 T 09-11-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 Pfam PF00266 Aminotransferase class-V 3 371 7.3E-84 T 09-11-2016 IPR000192 Aminotransferase class V domain CLOSPO_RS14625 853020a56ad74aa7487a03b7ec8235e2 384 PANTHER PTHR11601:SF43 1 384 4.2E-194 T 09-11-2016 CLOSPO_RS18055 5cb64e27125bbf05760ebdc06b70c1f4 202 Gene3D G3DSA:1.10.3210.10 11 152 2.5E-14 T 09-11-2016 IPR006674 HD domain CLOSPO_RS18055 5cb64e27125bbf05760ebdc06b70c1f4 202 Pfam PF08668 HDOD domain 26 65 4.9E-7 T 09-11-2016 IPR013976 Metal-dependent hydrolase HDOD CLOSPO_RS18055 5cb64e27125bbf05760ebdc06b70c1f4 202 SUPERFAMILY SSF109604 15 142 6.28E-14 T 09-11-2016 CLOSPO_RS18055 5cb64e27125bbf05760ebdc06b70c1f4 202 SMART SM00471 22 153 3.7E-5 T 09-11-2016 IPR003607 HD/PDEase domain CLOSPO_RS12960 b7a015bc1591518d06da4c262f7d1baa 468 Pfam PF13520 Amino acid permease 5 441 6.8E-63 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS12960 b7a015bc1591518d06da4c262f7d1baa 468 PIRSF PIRSF006060 1 468 3.9E-68 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS12960 b7a015bc1591518d06da4c262f7d1baa 468 PANTHER PTHR11785:SF322 1 468 3.4E-124 T 09-11-2016 CLOSPO_RS12960 b7a015bc1591518d06da4c262f7d1baa 468 PANTHER PTHR11785 1 468 3.4E-124 T 09-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CLOSPO_RS16365 dadde28dd846d05999c885f8d0cc6d19 178 Pfam PF11193 Protein of unknown function (DUF2812) 16 114 3.8E-20 T 09-11-2016 IPR021359 Protein of unknown function DUF2812 CLOSPO_RS17265 08210354cfcdaeb00c75f3447f0baf78 76 TIGRFAM TIGR04540 CLB_0814_fam: conserved hypothetical protein 2 74 1.2E-28 T 09-11-2016 IPR030902 Conserved hypothetical protein CLOSPO_RS18790 2eac35bf3799dfd18273f07d0082bc52 290 SUPERFAMILY SSF51735 2 255 8.3E-24 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS18790 2eac35bf3799dfd18273f07d0082bc52 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 189 7.4E-12 T 09-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CLOSPO_RS18790 2eac35bf3799dfd18273f07d0082bc52 290 Gene3D G3DSA:3.40.50.720 2 241 4.5E-19 T 09-11-2016 IPR016040 NAD(P)-binding domain CLOSPO_RS03250 f5c48b6caf3723a41cdac75822dceaef 70 Gene3D G3DSA:3.90.320.10 4 70 2.6E-5 T 09-11-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CLOSPO_RS16630 a76907a1fa2ed5d18eef8b4c4fd0f95d 357 SUPERFAMILY SSF82171 70 332 4.12E-5 T 09-11-2016 CLOSPO_RS15915 a828be3959de6ecdabd13f9861678351 63 SUPERFAMILY SSF47240 3 61 4.71E-5 T 09-11-2016 IPR009078 Ferritin-like superfamily CLOSPO_RS15915 a828be3959de6ecdabd13f9861678351 63 Gene3D G3DSA:1.20.1260.10 6 59 4.3E-4 T 09-11-2016 IPR012347 Ferritin-related CLOSPO_RS18955 54c51e17982f2acf0ad418d294eb4f31 209 SUPERFAMILY SSF53098 23 205 8.76E-8 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS18955 54c51e17982f2acf0ad418d294eb4f31 209 Pfam PF13482 RNase_H superfamily 25 205 1.6E-43 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS18955 54c51e17982f2acf0ad418d294eb4f31 209 Gene3D G3DSA:3.30.420.10 51 168 3.3E-5 T 09-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 CLOSPO_RS16195 a8ca8d0c92459f1bfe91193857568c4e 70 Gene3D G3DSA:1.10.260.40 1 63 5.8E-22 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16195 a8ca8d0c92459f1bfe91193857568c4e 70 PANTHER PTHR10245:SF61 1 60 2.9E-19 T 09-11-2016 CLOSPO_RS16195 a8ca8d0c92459f1bfe91193857568c4e 70 SMART SM00530 4 59 6.2E-14 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS16195 a8ca8d0c92459f1bfe91193857568c4e 70 SUPERFAMILY SSF47413 2 62 2.23E-17 T 09-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CLOSPO_RS16195 a8ca8d0c92459f1bfe91193857568c4e 70 PANTHER PTHR10245 1 60 2.9E-19 T 09-11-2016 CLOSPO_RS16195 a8ca8d0c92459f1bfe91193857568c4e 70 Pfam PF01381 Helix-turn-helix 5 59 7.2E-15 T 09-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOSPO_RS08135 50a1b5eaf0a37aed4e45f326bc2c1359 92 PANTHER PTHR24096 5 92 1.7E-14 T 09-11-2016 CLOSPO_RS08135 50a1b5eaf0a37aed4e45f326bc2c1359 92 Gene3D G3DSA:3.40.50.980 2 91 2.7E-15 T 09-11-2016 CLOSPO_RS08135 50a1b5eaf0a37aed4e45f326bc2c1359 92 SUPERFAMILY SSF56801 2 92 4.19E-15 T 09-11-2016 CLOSPO_RS08135 50a1b5eaf0a37aed4e45f326bc2c1359 92 Pfam PF00501 AMP-binding enzyme 2 92 3.2E-16 T 09-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CLOSPO_RS13795 7f31a49f63c7edb24a0ccd25e52707e4 279 SUPERFAMILY SSF48452 112 222 5.46E-5 T 09-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CLOSPO_RS13795 7f31a49f63c7edb24a0ccd25e52707e4 279 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 31 241 4.3E-80 T 09-11-2016 IPR018708 Protein of unknown function DUF2225 CLOSPO_RS14170 8c1204fde92f57f0a6df5aca94defc90 255 Gene3D G3DSA:3.90.1200.10 39 249 1.1E-18 T 09-11-2016 CLOSPO_RS13735 ead0544e8e8deb235094a6398737ee96 94 Pfam PF14276 Domain of unknown function (DUF4363) 2 93 3.6E-27 T 09-11-2016 IPR025373 Protein of unknown function DUF4363 CLOSPO_RS02025 2cdfd7b9396808efbb4b958154aa9087 251 PANTHER PTHR30572 2 250 8.0E-42 T 09-11-2016 CLOSPO_RS02025 2cdfd7b9396808efbb4b958154aa9087 251 Pfam PF02687 FtsX-like permease family 209 250 7.9E-9 T 09-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 CLOSPO_RS02025 2cdfd7b9396808efbb4b958154aa9087 251 Pfam PF12704 MacB-like periplasmic core domain 3 163 7.1E-17 T 09-11-2016 IPR025857 MacB-like periplasmic core domain CLOSPO_RS17660 a680a3387968f7c4d0b2a0ed2c01faa1 174 SUPERFAMILY SSF55729 41 174 1.45E-18 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17660 a680a3387968f7c4d0b2a0ed2c01faa1 174 Gene3D G3DSA:3.40.630.30 33 157 8.2E-19 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS17660 a680a3387968f7c4d0b2a0ed2c01faa1 174 Pfam PF13673 Acetyltransferase (GNAT) domain 51 155 3.1E-12 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS17360 3e3799ab07edad5eb9d572d3bf79739f 261 Pfam PF07155 ECF-type riboflavin transporter, S component 5 164 9.7E-10 T 09-11-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CLOSPO_RS08030 bc5b9fbb52b9f649e2916daa91209173 73 Pfam PF08367 Peptidase M16C associated 2 68 1.2E-14 T 09-11-2016 IPR013578 Peptidase M16C associated GO:0006508 CLOSPO_RS08030 bc5b9fbb52b9f649e2916daa91209173 73 SUPERFAMILY SSF63411 2 52 1.43E-6 T 09-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOSPO_RS18060 23470fcc2cc878d7c075781906ae269d 142 SUPERFAMILY SSF55729 42 141 1.49E-25 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18060 23470fcc2cc878d7c075781906ae269d 142 PANTHER PTHR23091 1 142 5.9E-21 T 09-11-2016 CLOSPO_RS18060 23470fcc2cc878d7c075781906ae269d 142 PANTHER PTHR23091:SF259 1 142 5.9E-21 T 09-11-2016 CLOSPO_RS18060 23470fcc2cc878d7c075781906ae269d 142 Gene3D G3DSA:3.40.630.30 48 141 1.6E-33 T 09-11-2016 IPR016181 Acyl-CoA N-acyltransferase CLOSPO_RS18060 23470fcc2cc878d7c075781906ae269d 142 Pfam PF00583 Acetyltransferase (GNAT) family 49 121 5.0E-11 T 09-11-2016 IPR000182 GNAT domain GO:0008080 CLOSPO_RS18360 9f7079c7a6352ff3dfb22544a2fdd7dd 179 Pfam PF01252 Signal peptidase (SPase) II 11 148 5.6E-12 T 09-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 CLOSPO_RS06760 d84706aa01ac7e05f8094fdc84147d58 145 PANTHER PTHR24960 57 141 1.7E-16 T 09-11-2016 CLOSPO_RS06760 d84706aa01ac7e05f8094fdc84147d58 145 PANTHER PTHR24960:SF25 57 141 1.7E-16 T 09-11-2016 CLOSPO_RS06760 d84706aa01ac7e05f8094fdc84147d58 145 Pfam PF04015 Domain of unknown function (DUF362) 13 143 3.2E-28 T 09-11-2016 IPR007160 Domain of unknown function DUF362 CLOSPO_RS16770 f80b930bf7ba1ac05015c11d2428f4e3 394 PANTHER PTHR36178 1 394 5.8E-200 T 09-11-2016 CLOSPO_RS16770 f80b930bf7ba1ac05015c11d2428f4e3 394 PANTHER PTHR36178:SF1 1 394 5.8E-200 T 09-11-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CLOSPO_RS16770 f80b930bf7ba1ac05015c11d2428f4e3 394 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 4 392 2.0E-115 T 09-11-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CLOSPO_RS16770 f80b930bf7ba1ac05015c11d2428f4e3 394 Pfam PF03616 Sodium/glutamate symporter 4 362 1.1E-122 T 09-11-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CLOSPO_RS12715 d0a70c054f75f8041563c86e5ef6c177 156 SUPERFAMILY SSF56784 13 119 2.34E-12 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS12715 d0a70c054f75f8041563c86e5ef6c177 156 Pfam PF08282 haloacid dehalogenase-like hydrolase 68 116 5.1E-6 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS12715 d0a70c054f75f8041563c86e5ef6c177 156 Gene3D G3DSA:3.40.50.1000 13 137 1.2E-12 T 09-11-2016 IPR023214 HAD-like domain CLOSPO_RS09400 ec574fc64a48953a3b6d10923c1088c9 136 SMART SM00646 30 134 2.2E-14 T 09-11-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 CLOSPO_RS09400 ec574fc64a48953a3b6d10923c1088c9 136 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 2 133 6.2E-15 T 09-11-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 CLOSPO_RS09400 ec574fc64a48953a3b6d10923c1088c9 136 Gene3D G3DSA:3.40.630.40 4 134 5.1E-19 T 09-11-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 CLOSPO_RS09400 ec574fc64a48953a3b6d10923c1088c9 136 SUPERFAMILY SSF53187 2 135 1.7E-24 T 09-11-2016 CLOSPO_RS07260 14959ea67a3f9cd16681e4336edc0eb6 296 Pfam PF07949 YbbR-like protein 18 102 2.5E-11 T 09-11-2016 IPR012505 YbbR-like CLOSPO_RS07260 14959ea67a3f9cd16681e4336edc0eb6 296 Pfam PF07949 YbbR-like protein 110 191 7.8E-7 T 09-11-2016 IPR012505 YbbR-like CLOSPO_RS07260 14959ea67a3f9cd16681e4336edc0eb6 296 PANTHER PTHR37804 2 296 8.6E-46 T 09-11-2016 CLOSPO_RS18440 6ee100aae9e128fa4fcffa46abe62913 201 Pfam PF13353 4Fe-4S single cluster domain 14 148 4.7E-37 T 09-11-2016 CLOSPO_RS18440 6ee100aae9e128fa4fcffa46abe62913 201 PANTHER PTHR30352:SF2 1 146 1.1E-51 T 09-11-2016 CLOSPO_RS18440 6ee100aae9e128fa4fcffa46abe62913 201 PANTHER PTHR30352 1 146 1.1E-51 T 09-11-2016 CLOSPO_RS18440 6ee100aae9e128fa4fcffa46abe62913 201 SUPERFAMILY SSF102114 26 103 2.94E-11 T 09-11-2016 CLOSPO_RS18440 6ee100aae9e128fa4fcffa46abe62913 201 Gene3D G3DSA:3.80.30.10 63 148 1.8E-11 T 09-11-2016 CLOSPO_RS18440 6ee100aae9e128fa4fcffa46abe62913 201 Pfam PF04055 Radical SAM superfamily 25 107 1.1E-7 T 09-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOSPO_RS18650 aa268b1cfda179b3f8040648a20b75ce 64 Gene3D G3DSA:1.20.1260.10 4 57 0.001 T 09-11-2016 IPR012347 Ferritin-related CLOSPO_RS13135 908f3aa1416bb4a3d376f72bad8a209c 139 PANTHER PTHR38459:SF1 2 139 2.6E-31 T 09-11-2016 CLOSPO_RS13135 908f3aa1416bb4a3d376f72bad8a209c 139 PANTHER PTHR38459 2 139 2.6E-31 T 09-11-2016 CLOSPO_RS13135 908f3aa1416bb4a3d376f72bad8a209c 139 Pfam PF04138 GtrA-like protein 21 138 1.3E-25 T 09-11-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CLOSPO_RS15215 ad7539afc28fb7c683658ec1593d6801 89 Pfam PF04977 Septum formation initiator 11 84 2.9E-19 T 09-11-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CLOSPO_RS16850 84c9aeadf94a664749a6a123b74a53ee 250 SUPERFAMILY SSF69318 26 135 6.54E-9 T 09-11-2016 CLOSPO_RS16850 84c9aeadf94a664749a6a123b74a53ee 250 SUPERFAMILY SSF69318 191 210 6.54E-9 T 09-11-2016 CLOSPO_RS16095 30ae50596979d2ec37a39a8bd5276b9b 229 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 125 203 2.5E-7 T 09-11-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CLOSPO_RS18390 fc934083ce2b68a0b2fd92d87fc34b5b 251 Pfam PF13803 Domain of unknown function (DUF4184) 1 248 1.7E-75 T 09-11-2016 IPR025238 Protein of unknown function DUF4184 CLOSPO_RS14605 4dee6e3d0468da4e1208620109bb3aaa 169 Pfam PF14584 Protein of unknown function (DUF4446) 15 162 8.3E-56 T 09-11-2016 IPR027981 Protein of unknown function DUF4446 CLOSPO_RS17800 84c1c44a572ae1186638a563894b0217 64 Pfam PF07485 Domain of Unknown Function (DUF1259) 7 53 9.4E-17 T 09-11-2016 IPR011094 Uncharacterised protein family, LppY/LpqO CLOSPO_RS15450 a9b60923fe0c391898867ac052836d6b 589 Pfam PF03553 Na+/H+ antiporter family 14 199 6.1E-6 T 09-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CLOSPO_RS15450 a9b60923fe0c391898867ac052836d6b 589 Pfam PF03553 Na+/H+ antiporter family 206 538 4.9E-59 T 09-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CLOSPO_RS15450 a9b60923fe0c391898867ac052836d6b 589 PANTHER PTHR33451 43 584 7.5E-238 T 09-11-2016 CLOSPO_RS15450 a9b60923fe0c391898867ac052836d6b 589 PANTHER PTHR33451:SF7 43 584 7.5E-238 T 09-11-2016 CLOSPO_RS16375 81910dbf305e06bb0a6e5280d7a47f5b 303 PANTHER PTHR39430 4 297 5.5E-20 T 09-11-2016 CLOSPO_RS16375 81910dbf305e06bb0a6e5280d7a47f5b 303 Pfam PF02517 CAAX protease self-immunity 150 243 1.1E-9 T 09-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 CLOSPO_RS14980 b374177b0c885e0538f5700eeeba602b 253 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 10 114 1.5E-8 T 09-11-2016 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOSPO_RS14980 b374177b0c885e0538f5700eeeba602b 253 TIGRFAM TIGR04482 D_pro_red_PrdD: proline reductase cluster protein PrdD 9 252 6.2E-111 T 09-11-2016 IPR031000 Proline reductase cluster protein PrdD CLOSPO_RS15025 c6cb683a7d25c250b3ac5f32748bd18d 193 Pfam PF10646 Sporulation and spore germination 54 163 3.9E-19 T 09-11-2016 IPR019606 GerMN domain CLOSPO_RS15025 c6cb683a7d25c250b3ac5f32748bd18d 193 SMART SM00909 81 168 1.7E-24 T 09-11-2016 IPR019606 GerMN domain CLOSPO_RS14525 a349eaea7f1b5da1063596b251762734 87 Pfam PF04025 Domain of unknown function (DUF370) 2 79 2.0E-8 T 09-11-2016 IPR007169 Uncharacterised protein family UPF0296 CLOSPO_RS13045 cfe8bac2558906261cace317597219b6 216 Pfam PF17118 Domain of unknown function (DUF5105) 55 185 1.5E-7 T 09-11-2016 IPR031343 Domain of unknown function DUF5105 CLOSPO_RS17165 1a112311207c949b476bc10afe5bca2b 75 Pfam PF11148 Protein of unknown function (DUF2922) 5 71 2.8E-23 T 09-11-2016 IPR021321 Protein of unknown function DUF2922 CLOSPO_RS16775 d5e6ead55b015e554016c41a28a76233 155 Gene3D G3DSA:1.10.238.10 84 122 7.8E-4 T 09-11-2016 IPR011992 EF-hand domain pair CLOSPO_RS15755 78fe02937448685260eb95d0374a7f00 57 TIGRFAM TIGR03602 streptolysinS: bacteriocin protoxin, streptolysin S family 1 56 4.2E-33 T 09-11-2016 IPR019891 Bacteriocin, streptolysin S, precursor CLOSPO_RS17550 27cac37779288e4421f63942996f0cc1 83 Pfam PF13684 Dihydroxyacetone kinase family 3 79 5.7E-20 T 09-11-2016 IPR033470 Uncharacterised protein, DhaK domain CLOSPO_RS17525 a7c4c3461e2f1aa0c86cf390c5667544 60 Pfam PF07870 Protein of unknown function (DUF1657) 23 57 5.5E-6 T 09-11-2016 IPR012452 Protein of unknown function DUF1657 CLOSPO_RS18165 445025518d3c36eb7b6a6fb1cc6d1a56 162 Pfam PF12822 Protein of unknown function (DUF3816) 4 150 1.5E-18 T 09-11-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215