locus-tag	class	description
D1O32_RS00020	COG1737	Transcriptional regulator
D1O32_RS00035	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS00045	COG0450	alkyl hydroperoxide reductase
D1O32_RS00050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D1O32_RS00055	COG2081	HI0933 family
D1O32_RS00070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS00075	COG2199	diguanylate cyclase activity
D1O32_RS00080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D1O32_RS00085	COG4481	Protein conserved in bacteria
D1O32_RS00095	COG0561	phosphatase activity
D1O32_RS00100	COG1368	sulfuric ester hydrolase activity
D1O32_RS00120	COG0012	GTP binding
D1O32_RS00125	COG4509	Sortase family
D1O32_RS00165	COG0534	Mate efflux family protein
D1O32_RS00185	COG0789	Transcriptional regulator
D1O32_RS00200	COG1876	peptidase activity
D1O32_RS00205	COG2843	Capsule synthesis protein
D1O32_RS00215	COG0459	protein refolding
D1O32_RS00220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D1O32_RS00235	COG1363	Peptidase, m42
D1O32_RS00240	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1O32_RS00245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS00250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS00250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS00255	COG0006	proline dipeptidase activity
D1O32_RS00260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D1O32_RS00290	COG0564	pseudouridine synthase activity
D1O32_RS00295	COG2226	methyltransferase
D1O32_RS00310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D1O32_RS00320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D1O32_RS00325	COG0254	rRNA binding
D1O32_RS00340	COG2801	Transposase and inactivated derivatives
D1O32_RS00390	COG4193	domain, Protein
D1O32_RS00390	COG5263	repeat protein
D1O32_RS00400	COG0463	Glycosyl transferase, family 2
D1O32_RS00430	COG1442	glycosyl transferase family 8
D1O32_RS00480	COG1216	Glycosyl transferase, family 2
D1O32_RS00480	COG0438	transferase activity, transferring glycosyl groups
D1O32_RS00485	COG1091	dTDP-4-dehydrorhamnose reductase activity
D1O32_RS00500	COG0438	transferase activity, transferring glycosyl groups
D1O32_RS00505	COG1216	Glycosyl transferase, family 2
D1O32_RS00530	COG0009	L-threonylcarbamoyladenylate synthase
D1O32_RS00535	COG0698	ribose 5-phosphate isomerase
D1O32_RS00540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D1O32_RS00545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D1O32_RS00560	COG0356	it plays a direct role in the translocation of protons across the membrane
D1O32_RS00575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D1O32_RS00580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D1O32_RS00585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D1O32_RS00590	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D1O32_RS00595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D1O32_RS00630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D1O32_RS00660	COG0493	'glutamate synthase
D1O32_RS00700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D1O32_RS00715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D1O32_RS00730	COG2706	6-phosphogluconolactonase activity
D1O32_RS00735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D1O32_RS00745	COG0436	Aminotransferase
D1O32_RS00765	COG0583	DNA-binding transcription factor activity
D1O32_RS00790	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS00795	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS00800	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS00820	COG3711	transcriptional antiterminator
D1O32_RS00830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D1O32_RS00835	COG0573	inorganic phosphate transmembrane transporter activity
D1O32_RS00840	COG0581	inorganic phosphate transmembrane transporter activity
D1O32_RS00845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D1O32_RS00850	COG0704	Plays a role in the regulation of phosphate uptake
D1O32_RS00855	COG0768	penicillin binding
D1O32_RS00880	COG0745	RESPONSE REGULATOR receiver
D1O32_RS00885	COG5002	protein histidine kinase activity
D1O32_RS00900	COG1882	Formate acetyltransferase
D1O32_RS00920	COG1131	(ABC) transporter
D1O32_RS00925	COG2188	Transcriptional regulator
D1O32_RS00935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D1O32_RS00940	COG0460	homoserine dehydrogenase
D1O32_RS00950	COG0083	homoserine kinase activity
D1O32_RS00970	COG1695	Transcriptional regulator
D1O32_RS00985	COG1983	PspC domain protein
D1O32_RS00990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D1O32_RS01010	COG1373	ATPase (AAA superfamily
D1O32_RS01020	COG0789	Transcriptional regulator
D1O32_RS01025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D1O32_RS01025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D1O32_RS01035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS01040	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS01055	COG0640	Transcriptional regulator
D1O32_RS01065	COG1309	transcriptional regulator
D1O32_RS01070	COG0456	acetyltransferase
D1O32_RS01075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D1O32_RS01090	COG1063	alcohol dehydrogenase
D1O32_RS01095	COG1733	regulation of RNA biosynthetic process
D1O32_RS01105	COG3279	Response regulator of the LytR AlgR family
D1O32_RS01120	COG1136	(ABC) transporter
D1O32_RS01140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D1O32_RS01160	COG2819	hydrolase of the alpha beta superfamily
D1O32_RS01165	COG0561	phosphatase activity
D1O32_RS01175	COG0285	dihydrofolate synthase activity
D1O32_RS01185	COG3773	Cell wall hydrolase
D1O32_RS01215	COG0215	cysteine-tRNA ligase activity
D1O32_RS01220	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D1O32_RS01225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D1O32_RS01235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D1O32_RS01245	COG0250	Participates in transcription elongation, termination and antitermination
D1O32_RS01250	COG0561	phosphatase activity
D1O32_RS01260	COG0584	glycerophosphoryl diester phosphodiesterase
D1O32_RS01265	COG1454	alcohol dehydrogenase
D1O32_RS01265	COG1012	belongs to the aldehyde dehydrogenase family
D1O32_RS01270	COG0504	CTP synthase activity
D1O32_RS01280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D1O32_RS01300	COG1671	Belongs to the UPF0178 family
D1O32_RS01305	COG0367	asparagine synthase
D1O32_RS01315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D1O32_RS01330	COG0740	serine-type endopeptidase activity
D1O32_RS01380	COG1136	(ABC) transporter
D1O32_RS01390	COG1695	Transcriptional regulator
D1O32_RS01445	COG1011	Hydrolase
D1O32_RS01450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D1O32_RS01480	COG0534	Mate efflux family protein
D1O32_RS01500	COG0561	phosphatase activity
D1O32_RS01520	COG1757	Na H antiporter
D1O32_RS01530	COG0679	Auxin Efflux Carrier
D1O32_RS01560	COG0242	peptide deformylase activity
D1O32_RS01565	COG0426	domain, Protein
D1O32_RS01575	COG0542	response to heat
D1O32_RS01580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D1O32_RS01590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D1O32_RS01595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D1O32_RS01600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D1O32_RS01610	COG3711	transcriptional antiterminator
D1O32_RS01610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS01615	COG1882	Formate acetyltransferase
D1O32_RS01620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D1O32_RS01625	COG1940	carbohydrate kinase activity
D1O32_RS01630	COG4166	transmembrane transport
D1O32_RS01635	COG4166	transmembrane transport
D1O32_RS01640	COG4166	transmembrane transport
D1O32_RS01645	COG0601	transmembrane transport
D1O32_RS01650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1O32_RS01655	COG0444	Belongs to the ABC transporter superfamily
D1O32_RS01660	COG4608	Belongs to the ABC transporter superfamily
D1O32_RS01670	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS01675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS01680	COG2195	Cleaves the N-terminal amino acid of tripeptides
D1O32_RS01690	COG1132	(ABC) transporter
D1O32_RS01695	COG1132	(ABC) transporter
D1O32_RS01705	COG1597	lipid kinase activity
D1O32_RS01725	COG0671	phosphoesterase, PA-phosphatase related
D1O32_RS01750	COG1192	Involved in chromosome partitioning
D1O32_RS01890	COG0741	lytic transglycosylase activity
D1O32_RS01905	COG3279	Response regulator of the LytR AlgR family
D1O32_RS01945	COG3279	Response regulator of the LytR AlgR family
D1O32_RS01970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D1O32_RS01980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D1O32_RS02020	COG2337	Toxic component of a toxin-antitoxin (TA) module
D1O32_RS02045	COG0673	inositol 2-dehydrogenase activity
D1O32_RS02080	COG2200	EAL domain
D1O32_RS02105	COG3191	aminopeptidase activity
D1O32_RS02110	COG4684	Psort location CytoplasmicMembrane, score
D1O32_RS02115	COG0406	alpha-ribazole phosphatase activity
D1O32_RS02120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D1O32_RS02125	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D1O32_RS02130	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D1O32_RS02155	COG1136	(ABC) transporter
D1O32_RS02170	COG1136	(ABC) transporter
D1O32_RS02185	COG0791	NLP P60 protein
D1O32_RS02185	COG1388	LysM domain
D1O32_RS02185	COG3103	Sh3 type 3 domain protein
D1O32_RS02190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D1O32_RS02190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D1O32_RS02210	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D1O32_RS02215	COG0194	GDP metabolic process
D1O32_RS02220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D1O32_RS02225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D1O32_RS02225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D1O32_RS02235	COG0631	protein serine/threonine phosphatase activity
D1O32_RS02240	COG2815	serine threonine protein kinase
D1O32_RS02240	COG0515	serine threonine protein kinase
D1O32_RS02245	COG1162	GTPase activity
D1O32_RS02250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1O32_RS02255	COG1564	THIamine pyrophosphokinase
D1O32_RS02270	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS02275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS02290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1O32_RS02295	COG1592	Rubrerythrin
D1O32_RS02295	COG1773	rubredoxin
D1O32_RS02330	COG1136	(ABC) transporter
D1O32_RS02345	COG5002	protein histidine kinase activity
D1O32_RS02360	COG1811	Na channel or pump
D1O32_RS02395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS02400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D1O32_RS02405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D1O32_RS02415	COG1362	aminopeptidase activity
D1O32_RS02420	COG0733	neurotransmitter:sodium symporter activity
D1O32_RS02430	COG1045	serine acetyltransferase
D1O32_RS02450	COG0037	tRNA processing
D1O32_RS02455	COG1959	2 iron, 2 sulfur cluster binding
D1O32_RS02460	COG0527	aspartate kinase activity
D1O32_RS02475	COG0778	Nitroreductase
D1O32_RS02495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D1O32_RS02500	COG0343	queuine tRNA-ribosyltransferase activity
D1O32_RS02510	COG0523	cobalamin synthesis protein
D1O32_RS02515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D1O32_RS02530	COG3944	biosynthesis protein
D1O32_RS02555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D1O32_RS02560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D1O32_RS02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1O32_RS02590	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D1O32_RS02595	COG4977	sequence-specific DNA binding
D1O32_RS02600	COG0366	Alpha amylase catalytic
D1O32_RS02605	COG3804	dihydrodipicolinate reductase
D1O32_RS02625	COG2364	Membrane
D1O32_RS02655	COG3344	reverse transcriptase
D1O32_RS02720	COG3851	Histidine kinase
D1O32_RS02725	COG2197	response regulator
D1O32_RS02745	COG3715	PTS system
D1O32_RS02750	COG3716	PTS system mannose fructose sorbose family IID component
D1O32_RS02765	COG2814	Major facilitator Superfamily
D1O32_RS02780	COG1349	DNA-binding transcription factor activity
D1O32_RS02785	COG1105	Belongs to the carbohydrate kinase PfkB family
D1O32_RS02800	COG2169	Transcriptional regulator
D1O32_RS02815	COG5001	Diguanylate cyclase
D1O32_RS02820	COG2188	Transcriptional regulator
D1O32_RS02830	COG3142	Participates in the control of copper homeostasis
D1O32_RS02835	COG0657	acetylesterase activity
D1O32_RS02850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D1O32_RS02855	COG0569	domain protein
D1O32_RS02860	COG2205	protein histidine kinase activity
D1O32_RS02865	COG0745	RESPONSE REGULATOR receiver
D1O32_RS02880	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1O32_RS02885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS02890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS02900	COG1446	asparaginase
D1O32_RS02905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D1O32_RS02910	COG3142	Participates in the control of copper homeostasis
D1O32_RS02915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1O32_RS02925	COG0583	DNA-binding transcription factor activity
D1O32_RS02935	COG2059	Chromate
D1O32_RS02945	COG1263	PTS System
D1O32_RS02945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS02945	COG2190	(PTS) system
D1O32_RS02955	COG1263	PTS System
D1O32_RS02955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS02955	COG2190	(PTS) system
D1O32_RS02960	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS02965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1O32_RS02970	COG0698	ribose 5-phosphate isomerase
D1O32_RS02980	COG5001	Diguanylate cyclase
D1O32_RS02980	COG1716	ATPase activity
D1O32_RS02985	COG1959	2 iron, 2 sulfur cluster binding
D1O32_RS02990	COG1511	domain protein
D1O32_RS03005	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS03010	COG2199	diguanylate cyclase activity
D1O32_RS03015	COG2203	Gaf domain
D1O32_RS03015	COG5001	Diguanylate cyclase
D1O32_RS03015	COG3706	GGDEF domain
D1O32_RS03015	COG4251	negative regulation of phosphorylation
D1O32_RS03025	COG0205	6-phosphofructokinase activity
D1O32_RS03035	COG3437	response regulator, receiver
D1O32_RS03040	COG2203	Gaf domain
D1O32_RS03040	COG2199	diguanylate cyclase activity
D1O32_RS03055	COG0583	DNA-binding transcription factor activity
D1O32_RS03070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D1O32_RS03075	COG0561	phosphatase activity
D1O32_RS03080	COG1217	gtp-binding protein TYPA
D1O32_RS03090	COG1454	alcohol dehydrogenase
D1O32_RS03095	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D1O32_RS03105	COG2211	Major facilitator Superfamily
D1O32_RS03120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D1O32_RS03125	COG0745	RESPONSE REGULATOR receiver
D1O32_RS03130	COG2770	Histidine kinase
D1O32_RS03130	COG2205	protein histidine kinase activity
D1O32_RS03140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D1O32_RS03150	COG0849	cell division
D1O32_RS03155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D1O32_RS03160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D1O32_RS03170	COG1191	sigma factor activity
D1O32_RS03175	COG1191	sigma factor activity
D1O32_RS03185	COG1799	cell septum assembly
D1O32_RS03200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D1O32_RS03205	COG1686	Belongs to the peptidase S11 family
D1O32_RS03210	COG0561	phosphatase activity
D1O32_RS03215	COG1349	DNA-binding transcription factor activity
D1O32_RS03225	COG0546	phosphoglycolate phosphatase activity
D1O32_RS03235	COG1482	cell wall glycoprotein biosynthetic process
D1O32_RS03245	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D1O32_RS03250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D1O32_RS03255	COG0217	transcriptional regulatory protein
D1O32_RS03260	COG2081	HI0933 family
D1O32_RS03270	COG3340	Belongs to the peptidase S51 family
D1O32_RS03285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D1O32_RS03290	COG1971	Probably functions as a manganese efflux pump
D1O32_RS03295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D1O32_RS03300	COG3870	Protein conserved in bacteria
D1O32_RS03305	COG0285	dihydrofolate synthase activity
D1O32_RS03325	COG1132	(ABC) transporter
D1O32_RS03330	COG1132	(ABC) transporter
D1O32_RS03350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1O32_RS03365	COG2190	(PTS) system
D1O32_RS03365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS03365	COG1263	PTS System
D1O32_RS03370	COG3711	transcriptional antiterminator
D1O32_RS03385	COG1640	4-alpha-glucanotransferase
D1O32_RS03395	COG0512	Glutamine amidotransferase of anthranilate synthase
D1O32_RS03395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D1O32_RS03415	COG0133	tryptophan synthase activity
D1O32_RS03430	COG1902	pentaerythritol trinitrate reductase activity
D1O32_RS03440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D1O32_RS03450	COG0697	spore germination
D1O32_RS03465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D1O32_RS03475	COG0583	DNA-binding transcription factor activity
D1O32_RS03485	COG0534	Mate efflux family protein
D1O32_RS03495	COG4989	oxidoreductase activity
D1O32_RS03520	COG1686	Belongs to the peptidase S11 family
D1O32_RS03530	COG0700	Nucleoside recognition
D1O32_RS03535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D1O32_RS03545	COG2738	Putative neutral zinc metallopeptidase
D1O32_RS03555	COG3935	DnaD domain protein
D1O32_RS03560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D1O32_RS03580	COG2203	Gaf domain
D1O32_RS03580	COG2199	diguanylate cyclase activity
D1O32_RS03585	COG4499	WXG100 protein secretion system (Wss), protein YukC
D1O32_RS03585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1O32_RS03590	COG4499	WXG100 protein secretion system (Wss), protein YukC
D1O32_RS03590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1O32_RS03595	COG3331	DNA recombination
D1O32_RS03610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D1O32_RS03615	COG0569	domain protein
D1O32_RS03630	COG3706	GGDEF domain
D1O32_RS03660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D1O32_RS03670	COG1086	Polysaccharide biosynthesis protein
D1O32_RS03685	COG0438	transferase activity, transferring glycosyl groups
D1O32_RS03695	COG0463	Glycosyl transferase, family 2
D1O32_RS03695	COG1216	Glycosyl transferase, family 2
D1O32_RS03705	COG3594	Acyltransferase
D1O32_RS03740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D1O32_RS03760	COG1301	dicarboxylic acid transport
D1O32_RS03795	COG1674	ftsk spoiiie
D1O32_RS03800	COG2946	Replication initiation factor
D1O32_RS03850	COG0791	NLP P60 protein
D1O32_RS03850	COG0741	lytic transglycosylase activity
D1O32_RS03945	COG0659	secondary active sulfate transmembrane transporter activity
D1O32_RS03950	COG0534	Mate efflux family protein
D1O32_RS03970	COG1091	dTDP-4-dehydrorhamnose reductase activity
D1O32_RS03975	COG1301	dicarboxylic acid transport
D1O32_RS03990	COG4667	esterase of the alpha-beta hydrolase superfamily
D1O32_RS03995	COG1523	belongs to the glycosyl hydrolase 13 family
D1O32_RS04005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D1O32_RS04015	COG1739	Uncharacterized protein family UPF0029
D1O32_RS04020	COG1307	EDD domain protein, DegV family
D1O32_RS04040	COG1702	phosphate starvation-inducible protein PhoH
D1O32_RS04045	COG0745	RESPONSE REGULATOR receiver
D1O32_RS04050	COG5002	protein histidine kinase activity
D1O32_RS04055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1O32_RS04065	COG0561	phosphatase activity
D1O32_RS04090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D1O32_RS04095	COG1160	GTP binding
D1O32_RS04110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D1O32_RS04115	COG2001	Belongs to the MraZ family
D1O32_RS04120	COG0275	rRNA processing
D1O32_RS04130	COG0768	penicillin binding
D1O32_RS04135	COG0768	penicillin binding
D1O32_RS04160	COG4536	flavin adenine dinucleotide binding
D1O32_RS04165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D1O32_RS04180	COG0587	DNA-directed DNA polymerase activity
D1O32_RS04185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D1O32_RS04185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D1O32_RS04195	COG0237	dephospho-CoA kinase activity
D1O32_RS04215	COG0469	pyruvate kinase activity
D1O32_RS04220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D1O32_RS04225	COG1307	EDD domain protein, DegV family
D1O32_RS04240	COG0242	peptide deformylase activity
D1O32_RS04255	COG0772	Belongs to the SEDS family
D1O32_RS04275	COG0742	ribosomal rna small subunit methyltransferase
D1O32_RS04280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D1O32_RS04290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D1O32_RS04300	COG1278	Cold shock
D1O32_RS04305	COG0653	protein targeting
D1O32_RS04310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D1O32_RS04315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1O32_RS04325	COG2884	Cell division ATP-binding protein ftsE
D1O32_RS04330	COG2177	Part of the ABC transporter FtsEX involved in
D1O32_RS04335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D1O32_RS04350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D1O32_RS04355	COG1051	belongs to the nudix hydrolase family
D1O32_RS04360	COG2183	response to ionizing radiation
D1O32_RS04370	COG1278	Cold shock
D1O32_RS04380	COG1929	Belongs to the glycerate kinase type-1 family
D1O32_RS04385	COG1074	ATP-dependent DNA helicase activity
D1O32_RS04410	COG1396	sequence-specific DNA binding
D1O32_RS04425	COG0534	Mate efflux family protein
D1O32_RS04430	COG1846	Transcriptional regulator
D1O32_RS04445	COG2116	formate transmembrane transporter activity
D1O32_RS04455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D1O32_RS04475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1O32_RS04490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D1O32_RS04505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D1O32_RS04510	COG1737	Transcriptional regulator
D1O32_RS04515	COG0165	Argininosuccinate lyase
D1O32_RS04525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D1O32_RS04530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D1O32_RS04550	COG3711	transcriptional antiterminator
D1O32_RS04550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS04555	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS04555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS04560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS04560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS04565	COG3715	PTS system
D1O32_RS04570	COG3716	PTS system mannose fructose sorbose family IID component
D1O32_RS04575	COG0246	Mannitol dehydrogenase
D1O32_RS04580	COG1408	metallophosphoesterase
D1O32_RS04585	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D1O32_RS04595	COG3118	belongs to the thioredoxin family
D1O32_RS04625	COG2264	protein methyltransferase activity
D1O32_RS04660	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1O32_RS04670	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS04675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1O32_RS04680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D1O32_RS04685	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D1O32_RS04690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D1O32_RS04700	COG1609	Transcriptional regulator
D1O32_RS04715	COG1619	proteins homologs of microcin C7 resistance protein MccF
D1O32_RS04735	COG2207	Transcriptional regulator
D1O32_RS04735	COG3708	Transcriptional regulator
D1O32_RS04795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D1O32_RS04820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D1O32_RS04825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D1O32_RS04830	COG0543	2 iron, 2 sulfur cluster binding
D1O32_RS04835	COG0167	dihydroorotate dehydrogenase activity
D1O32_RS04840	COG0210	DNA helicase
D1O32_RS04845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D1O32_RS04880	COG1187	pseudouridine synthase activity
D1O32_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS04900	COG1254	Belongs to the acylphosphatase family
D1O32_RS04905	COG0252	asparaginase activity
D1O32_RS04950	COG0670	Belongs to the BI1 family
D1O32_RS04955	COG0534	Mate efflux family protein
D1O32_RS04960	COG0577	efflux transmembrane transporter activity
D1O32_RS04965	COG1136	(ABC) transporter
D1O32_RS04970	COG5002	protein histidine kinase activity
D1O32_RS04990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D1O32_RS05000	COG1827	regulation of RNA biosynthetic process
D1O32_RS05010	COG0561	phosphatase activity
D1O32_RS05025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1O32_RS05030	COG1247	-acetyltransferase
D1O32_RS05050	COG0443	Heat shock 70 kDa protein
D1O32_RS05055	COG0484	heat shock protein binding
D1O32_RS05075	COG0488	(ABC) transporter
D1O32_RS05085	COG3279	Response regulator of the LytR AlgR family
D1O32_RS05110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D1O32_RS05115	COG0561	phosphatase activity
D1O32_RS05125	COG0534	Mate efflux family protein
D1O32_RS05130	COG2195	Cleaves the N-terminal amino acid of tripeptides
D1O32_RS05140	COG0646	methionine synthase
D1O32_RS05140	COG1410	methionine synthase
D1O32_RS05150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D1O32_RS05160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D1O32_RS05165	COG0564	pseudouridine synthase activity
D1O32_RS05185	COG1193	negative regulation of DNA recombination
D1O32_RS05190	COG0322	excinuclease ABC activity
D1O32_RS05195	COG2197	response regulator
D1O32_RS05200	COG1876	peptidase activity
D1O32_RS05205	COG2239	Acts as a magnesium transporter
D1O32_RS05210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D1O32_RS05215	COG2239	Acts as a magnesium transporter
D1O32_RS05220	COG0561	phosphatase activity
D1O32_RS05225	COG0534	Mate efflux family protein
D1O32_RS05230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D1O32_RS05250	COG0513	Belongs to the DEAD box helicase family
D1O32_RS05255	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D1O32_RS05265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D1O32_RS05270	COG1164	Oligoendopeptidase f
D1O32_RS05275	COG0268	Binds directly to 16S ribosomal RNA
D1O32_RS05295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D1O32_RS05300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D1O32_RS05305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D1O32_RS05310	COG0561	phosphatase activity
D1O32_RS05340	COG1940	carbohydrate kinase activity
D1O32_RS05345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D1O32_RS05345	COG0723	plastoquinol--plastocyanin reductase activity
D1O32_RS05370	COG0561	phosphatase activity
D1O32_RS05380	COG0673	inositol 2-dehydrogenase activity
D1O32_RS05385	COG0673	inositol 2-dehydrogenase activity
D1O32_RS05390	COG0561	phosphatase activity
D1O32_RS05410	COG1136	(ABC) transporter
D1O32_RS05425	COG1940	carbohydrate kinase activity
D1O32_RS05430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D1O32_RS05440	COG0006	proline dipeptidase activity
D1O32_RS05450	COG1971	Probably functions as a manganese efflux pump
D1O32_RS05460	COG0561	phosphatase activity
D1O32_RS05465	COG1811	Na channel or pump
D1O32_RS05470	COG2252	PERMEase
D1O32_RS05495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D1O32_RS05500	COG1620	l-lactate permease
D1O32_RS05515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D1O32_RS05525	COG1686	Belongs to the peptidase S11 family
D1O32_RS05535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D1O32_RS05545	COG2190	(PTS) system
D1O32_RS05550	COG3711	transcriptional antiterminator
D1O32_RS05555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS05555	COG1263	PTS System
D1O32_RS05565	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS05585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D1O32_RS05590	COG1686	Belongs to the peptidase S11 family
D1O32_RS05600	COG2172	sigma factor antagonist activity
D1O32_RS05625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D1O32_RS05640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D1O32_RS05650	COG3557	Belongs to the UPF0374 family
D1O32_RS05655	COG0802	atpase or kinase
D1O32_RS05660	COG1214	PFAM Peptidase M22, glycoprotease
D1O32_RS05665	COG0456	acetyltransferase
D1O32_RS05680	COG0017	Asparaginyl-tRNA synthetase
D1O32_RS05690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D1O32_RS05700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D1O32_RS05700	COG0574	Belongs to the PEP-utilizing enzyme family
D1O32_RS05730	COG0674	pyruvate-flavodoxin oxidoreductase activity
D1O32_RS05730	COG1013	pyruvate-flavodoxin oxidoreductase activity
D1O32_RS05730	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D1O32_RS05730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1O32_RS05765	COG3481	metal-dependent phosphohydrolase, HD sub domain
D1O32_RS05780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D1O32_RS05790	COG0571	ribonuclease III activity
D1O32_RS05800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D1O32_RS05830	COG1176	ABC-type spermidine putrescine transport system, permease component I
D1O32_RS05835	COG1177	transmembrane transport
D1O32_RS05900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D1O32_RS05905	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D1O32_RS05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D1O32_RS05915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D1O32_RS05920	COG0131	Imidazoleglycerol-phosphate dehydratase
D1O32_RS05925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D1O32_RS05935	COG0107	imidazoleglycerol-phosphate synthase activity
D1O32_RS05940	COG0140	phosphoribosyl-ATP diphosphatase activity
D1O32_RS05940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D1O32_RS05945	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS05950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D1O32_RS05960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D1O32_RS05990	COG0583	DNA-binding transcription factor activity
D1O32_RS05995	COG0726	polysaccharide deacetylase
D1O32_RS06005	COG1966	Carbon starvation protein
D1O32_RS06010	COG1309	transcriptional regulator
D1O32_RS06020	COG0436	Aminotransferase
D1O32_RS06025	COG1309	transcriptional regulator
D1O32_RS06035	COG1132	(ABC) transporter
D1O32_RS06055	COG4716	Myosin-crossreactive antigen
D1O32_RS06070	COG0148	phosphopyruvate hydratase activity
D1O32_RS06075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS06085	COG1482	cell wall glycoprotein biosynthetic process
D1O32_RS06100	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS06105	COG2357	RelA SpoT domain protein
D1O32_RS06110	COG0534	Mate efflux family protein
D1O32_RS06115	COG0583	DNA-binding transcription factor activity
D1O32_RS06130	COG2843	Capsule synthesis protein
D1O32_RS06140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D1O32_RS06165	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D1O32_RS06215	COG2759	Belongs to the formate--tetrahydrofolate ligase family
D1O32_RS06220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D1O32_RS06225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D1O32_RS06230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D1O32_RS06235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D1O32_RS06240	COG0138	bifunctional purine biosynthesis protein purh
D1O32_RS06245	COG0151	Belongs to the GarS family
D1O32_RS06250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D1O32_RS06255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D1O32_RS06265	COG0124	histidyl-tRNA synthetase
D1O32_RS06270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D1O32_RS06280	COG2337	Toxic component of a toxin-antitoxin (TA) module
D1O32_RS06285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D1O32_RS06300	COG1609	Transcriptional regulator
D1O32_RS06320	COG3326	Membrane
D1O32_RS06325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1O32_RS06335	COG0534	Mate efflux family protein
D1O32_RS06345	COG0588	phosphoglycerate mutase activity
D1O32_RS06375	COG1121	(ABC) transporter
D1O32_RS06380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1O32_RS06390	COG0196	riboflavin kinase activity
D1O32_RS06405	COG1104	cysteine desulfurase activity
D1O32_RS06420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D1O32_RS06425	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D1O32_RS06440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D1O32_RS06445	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS06450	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D1O32_RS06455	COG0745	RESPONSE REGULATOR receiver
D1O32_RS06460	COG5002	protein histidine kinase activity
D1O32_RS06465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D1O32_RS06470	COG1196	nuclear chromosome segregation
D1O32_RS06475	COG0552	protein localization to endoplasmic reticulum
D1O32_RS06480	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D1O32_RS06485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D1O32_RS06500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D1O32_RS06505	COG0336	Belongs to the RNA methyltransferase TrmD family
D1O32_RS06510	COG0335	large ribosomal subunit rRNA binding
D1O32_RS06515	COG0681	Belongs to the peptidase S26 family
D1O32_RS06525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D1O32_RS06530	COG0758	DNA mediated transformation
D1O32_RS06535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D1O32_RS06540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D1O32_RS06545	COG4974	Belongs to the 'phage' integrase family
D1O32_RS06550	COG0052	Belongs to the universal ribosomal protein uS2 family
D1O32_RS06555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D1O32_RS06565	COG0233	cytoplasmic translational termination
D1O32_RS06575	COG4589	Belongs to the CDS family
D1O32_RS06580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D1O32_RS06595	COG0779	Required for maturation of 30S ribosomal subunits
D1O32_RS06600	COG0195	Participates in both transcription termination and antitermination
D1O32_RS06605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D1O32_RS06610	COG1358	cellular component organization or biogenesis
D1O32_RS06615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D1O32_RS06620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D1O32_RS06645	COG1187	pseudouridine synthase activity
D1O32_RS06650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D1O32_RS06655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D1O32_RS06665	COG0736	holo-[acyl-carrier-protein] synthase activity
D1O32_RS06675	COG0481	GTPase activity
D1O32_RS06680	COG0768	penicillin binding
D1O32_RS06685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D1O32_RS06690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1O32_RS06725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D1O32_RS06730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D1O32_RS06755	COG1722	exodeoxyribonuclease VII activity
D1O32_RS06760	COG0142	geranyltranstransferase activity
D1O32_RS06765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D1O32_RS06770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D1O32_RS06775	COG0497	DNA recombination
D1O32_RS06780	COG0750	zinc metalloprotease
D1O32_RS06790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D1O32_RS06810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS06815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D1O32_RS06820	COG2848	UPF0210 protein
D1O32_RS06830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS06840	COG0622	Phosphoesterase
D1O32_RS06850	COG0826	peptidase U32
D1O32_RS06855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D1O32_RS06860	COG2226	methyltransferase
D1O32_RS06865	COG0799	negative regulation of ribosome biogenesis
D1O32_RS06870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D1O32_RS06875	COG1534	Rna-binding protein
D1O32_RS06880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D1O32_RS06890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D1O32_RS06895	COG0187	DNA topoisomerase II activity
D1O32_RS06900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D1O32_RS06910	COG3763	UPF0154 protein
D1O32_RS06920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D1O32_RS06925	COG4224	UPF0291 protein
D1O32_RS06935	COG0612	Peptidase, M16
D1O32_RS06955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D1O32_RS06960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D1O32_RS06985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D1O32_RS06995	COG2323	membrane
D1O32_RS07000	COG2217	Heavy metal translocating P-type atpase
D1O32_RS07005	COG0640	Transcriptional regulator
D1O32_RS07015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D1O32_RS07020	COG0372	Belongs to the citrate synthase family
D1O32_RS07025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D1O32_RS07035	COG1956	GAF domain-containing protein
D1O32_RS07040	COG0726	polysaccharide deacetylase
D1O32_RS07050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D1O32_RS07055	COG1486	melibiose metabolic process
D1O32_RS07060	COG0563	adenylate kinase activity
D1O32_RS07065	COG5002	protein histidine kinase activity
D1O32_RS07065	COG3850	Histidine kinase
D1O32_RS07070	COG0745	RESPONSE REGULATOR receiver
D1O32_RS07085	COG2080	2 iron, 2 sulfur cluster binding
D1O32_RS07085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D1O32_RS07105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D1O32_RS07105	COG3608	succinylglutamate desuccinylase aspartoacylase
D1O32_RS07110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D1O32_RS07115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D1O32_RS07115	COG3608	succinylglutamate desuccinylase aspartoacylase
D1O32_RS07120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D1O32_RS07120	COG0425	Belongs to the sulfur carrier protein TusA family
D1O32_RS07125	COG0709	Synthesizes selenophosphate from selenide and ATP
D1O32_RS07135	COG2005	Transcriptional regulator
D1O32_RS07145	COG0725	ABC transporter, periplasmic molybdate-binding protein
D1O32_RS07155	COG4149	molybdate abc transporter
D1O32_RS07160	COG0521	Mo-molybdopterin cofactor biosynthetic process
D1O32_RS07200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D1O32_RS07225	COG2199	diguanylate cyclase activity
D1O32_RS07230	COG0038	chloride channel
D1O32_RS07260	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D1O32_RS07340	COG0534	Mate efflux family protein
D1O32_RS07365	COG1131	(ABC) transporter
D1O32_RS07375	COG1124	(ABC) transporter
D1O32_RS07380	COG0444	Belongs to the ABC transporter superfamily
D1O32_RS07385	COG0747	negative chemotaxis
D1O32_RS07390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1O32_RS07395	COG0601	transmembrane transport
D1O32_RS07400	COG2226	methyltransferase
D1O32_RS07410	COG1691	(AIR) carboxylase
D1O32_RS07470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D1O32_RS07495	COG5002	protein histidine kinase activity
D1O32_RS07550	COG3437	response regulator, receiver
D1O32_RS07620	COG0519	Catalyzes the synthesis of GMP from XMP
D1O32_RS07620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D1O32_RS07625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D1O32_RS07630	COG0583	DNA-binding transcription factor activity
D1O32_RS07635	COG1546	Belongs to the CinA family
D1O32_RS07635	COG1058	Belongs to the CinA family
D1O32_RS07645	COG2188	Transcriptional regulator
D1O32_RS07650	COG1132	(ABC) transporter
D1O32_RS07665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D1O32_RS07670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D1O32_RS07680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D1O32_RS07685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D1O32_RS07690	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D1O32_RS07690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D1O32_RS07705	COG0436	Aminotransferase
D1O32_RS07710	COG1126	abc transporter atp-binding protein
D1O32_RS07715	COG0765	amino acid transport
D1O32_RS07730	COG0561	phosphatase activity
D1O32_RS07735	COG1132	(ABC) transporter
D1O32_RS07910	COG0740	serine-type endopeptidase activity
D1O32_RS07970	COG2226	methyltransferase
D1O32_RS08070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1O32_RS08125	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS08130	COG1737	Transcriptional regulator
D1O32_RS08155	COG1309	transcriptional regulator
D1O32_RS08190	COG0745	RESPONSE REGULATOR receiver
D1O32_RS08195	COG5002	protein histidine kinase activity
D1O32_RS08200	COG0577	efflux transmembrane transporter activity
D1O32_RS08200	COG1136	(ABC) transporter
D1O32_RS08210	COG0424	maF-like protein
D1O32_RS08215	COG1185	polyribonucleotide nucleotidyltransferase activity
D1O32_RS08230	COG2323	membrane
D1O32_RS08250	COG0572	uridine kinase
D1O32_RS08255	COG0826	peptidase U32
D1O32_RS08265	COG4122	O-methyltransferase activity
D1O32_RS08275	COG2706	6-phosphogluconolactonase activity
D1O32_RS08280	COG3906	Belongs to the UPF0473 family
D1O32_RS08285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D1O32_RS08290	COG4472	Bacterial protein of unknown function (DUF965)
D1O32_RS08295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D1O32_RS08300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D1O32_RS08355	COG3023	N-Acetylmuramoyl-L-alanine amidase
D1O32_RS08360	COG1266	CAAX protease self-immunity
D1O32_RS08370	COG2337	Toxic component of a toxin-antitoxin (TA) module
D1O32_RS08375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1O32_RS08385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D1O32_RS08390	COG0463	Glycosyl transferase, family 2
D1O32_RS08390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D1O32_RS08395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D1O32_RS08400	COG1134	teichoic acid transport
D1O32_RS08405	COG1682	transport, permease protein
D1O32_RS08410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D1O32_RS08425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D1O32_RS08445	COG1228	amidohydrolase
D1O32_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS08470	COG1104	cysteine desulfurase activity
D1O32_RS08475	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS08490	COG0561	phosphatase activity
D1O32_RS08495	COG0583	DNA-binding transcription factor activity
D1O32_RS08505	COG2203	Gaf domain
D1O32_RS08505	COG2199	diguanylate cyclase activity
D1O32_RS08510	COG2203	Gaf domain
D1O32_RS08510	COG2199	diguanylate cyclase activity
D1O32_RS08525	COG1309	transcriptional regulator
D1O32_RS08530	COG0495	leucyl-tRNA aminoacylation
D1O32_RS08540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D1O32_RS08545	COG1242	4 iron, 4 sulfur cluster binding
D1O32_RS08555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D1O32_RS08560	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D1O32_RS08565	COG1098	S1 RNA binding domain
D1O32_RS08570	COG0166	Belongs to the GPI family
D1O32_RS08635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D1O32_RS08640	COG0719	Fe-S assembly protein
D1O32_RS08645	COG0822	iron-sulfur transferase activity
D1O32_RS08650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D1O32_RS08655	COG0719	Fe-S assembly protein
D1O32_RS08660	COG0396	ATPase activity
D1O32_RS08685	COG0537	adenosine 5'-monophosphoramidase activity
D1O32_RS08705	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS08720	COG1780	Probably involved in ribonucleotide reductase function
D1O32_RS08750	COG0697	spore germination
D1O32_RS08765	COG0561	phosphatase activity
D1O32_RS08780	COG1362	aminopeptidase activity
D1O32_RS08785	COG0531	amino acid
D1O32_RS08815	COG1695	Transcriptional regulator
D1O32_RS08850	COG0561	phosphatase activity
D1O32_RS08855	COG2217	Heavy metal translocating P-type atpase
D1O32_RS08865	COG1132	(ABC) transporter
D1O32_RS08870	COG4988	ABC transporter
D1O32_RS08880	COG2832	Protein of unknown function (DUF454)
D1O32_RS08895	COG1737	Transcriptional regulator
D1O32_RS08900	COG1234	tRNA 3'-trailer cleavage
D1O32_RS08915	COG2199	diguanylate cyclase activity
D1O32_RS08925	COG3681	Belongs to the UPF0597 family
D1O32_RS08930	COG0583	DNA-binding transcription factor activity
D1O32_RS08935	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS08940	COG0583	DNA-binding transcription factor activity
D1O32_RS08970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1O32_RS08980	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS08985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS09025	COG2878	Part of a membrane complex involved in electron transport
D1O32_RS09030	COG4657	Part of a membrane complex involved in electron transport
D1O32_RS09035	COG4660	Part of a membrane complex involved in electron transport
D1O32_RS09040	COG4659	FMN binding
D1O32_RS09045	COG4658	electron transport chain
D1O32_RS09050	COG4656	Part of a membrane complex involved in electron transport
D1O32_RS09055	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D1O32_RS09060	COG0469	pyruvate kinase activity
D1O32_RS09115	COG1136	(ABC) transporter
D1O32_RS09125	COG0745	RESPONSE REGULATOR receiver
D1O32_RS09130	COG0642	Histidine kinase
D1O32_RS09140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D1O32_RS09145	COG2384	SAM-dependent methyltransferase
D1O32_RS09150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D1O32_RS09155	COG0358	DNA primase activity
D1O32_RS09160	COG0423	glycine-tRNA ligase activity
D1O32_RS09180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D1O32_RS09190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D1O32_RS09195	COG3271	cysteine-type peptidase activity
D1O32_RS09195	COG2274	protein secretion by the type I secretion system
D1O32_RS09200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D1O32_RS09205	COG1473	amidohydrolase
D1O32_RS09210	COG2171	N-acyltransferase activity
D1O32_RS09215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D1O32_RS09220	COG0488	(ABC) transporter
D1O32_RS09235	COG0702	epimerase
D1O32_RS09280	COG1086	Polysaccharide biosynthesis protein
D1O32_RS09295	COG1216	Glycosyl transferase, family 2
D1O32_RS09340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D1O32_RS09345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D1O32_RS09360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1O32_RS09370	COG2337	Toxic component of a toxin-antitoxin (TA) module
D1O32_RS09380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS09385	COG0363	glucosamine-6-phosphate deaminase activity
D1O32_RS09400	COG0588	phosphoglycerate mutase activity
D1O32_RS09405	COG3250	beta-galactosidase activity
D1O32_RS09410	COG1917	Cupin 2, conserved barrel domain protein
D1O32_RS09410	COG4977	sequence-specific DNA binding
D1O32_RS09415	COG1461	Dihydroxyacetone kinase
D1O32_RS09420	COG1302	Protein conserved in bacteria
D1O32_RS09425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D1O32_RS09435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D1O32_RS09435	COG3064	Membrane
D1O32_RS09435	COG3583	domain protein
D1O32_RS09445	COG0443	Heat shock 70 kDa protein
D1O32_RS09455	COG1420	regulation of RNA biosynthetic process
D1O32_RS09460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D1O32_RS09465	COG1760	l-serine dehydratase
D1O32_RS09475	COG2333	competence protein COMEC
D1O32_RS09475	COG0658	competence protein
D1O32_RS09485	COG2255	four-way junction helicase activity
D1O32_RS09490	COG0632	four-way junction helicase activity
D1O32_RS09495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D1O32_RS09500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D1O32_RS09515	COG1994	Peptidase M50
D1O32_RS09525	COG2894	cell division
D1O32_RS09545	COG2003	Belongs to the UPF0758 family
D1O32_RS09550	COG1268	BioY protein
D1O32_RS09585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D1O32_RS09590	COG0544	peptidyl-prolyl cis-trans isomerase activity
D1O32_RS09605	COG0622	Phosphoesterase
D1O32_RS09650	COG2217	Heavy metal translocating P-type atpase
D1O32_RS09710	COG1725	Transcriptional regulator
D1O32_RS09715	COG1131	(ABC) transporter
D1O32_RS09735	COG0583	DNA-binding transcription factor activity
D1O32_RS09755	COG3546	catalase activity
D1O32_RS09760	COG1078	dGTPase activity
D1O32_RS09810	COG0347	Belongs to the P(II) protein family
D1O32_RS09825	COG0205	6-phosphofructokinase activity
D1O32_RS09830	COG0708	Exodeoxyribonuclease III
D1O32_RS09835	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D1O32_RS09860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D1O32_RS09875	COG0784	Response regulator, receiver
D1O32_RS09875	COG5002	protein histidine kinase activity
D1O32_RS09880	COG0784	Response regulator, receiver
D1O32_RS09880	COG2205	protein histidine kinase activity
D1O32_RS09890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D1O32_RS09895	COG0419	ATPase involved in DNA repair
D1O32_RS09900	COG0420	3'-5' exonuclease activity
D1O32_RS09925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D1O32_RS09965	COG1459	type II secretion system
D1O32_RS09970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D1O32_RS10025	COG3437	response regulator, receiver
D1O32_RS10040	COG0714	Associated with various cellular activities
D1O32_RS10050	COG2205	protein histidine kinase activity
D1O32_RS10050	COG0784	Response regulator, receiver
D1O32_RS10055	COG0628	permease
D1O32_RS10065	COG1605	Chorismate mutase
D1O32_RS10065	COG0077	Prephenate dehydratase
D1O32_RS10070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D1O32_RS10075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D1O32_RS10080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D1O32_RS10085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D1O32_RS10110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D1O32_RS10110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
D1O32_RS10130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D1O32_RS10135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D1O32_RS10145	COG1940	carbohydrate kinase activity
D1O32_RS10160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D1O32_RS10170	COG1187	pseudouridine synthase activity
D1O32_RS10185	COG1323	Belongs to the UPF0348 family
D1O32_RS10210	COG0072	phenylalanine-tRNA ligase activity
D1O32_RS10210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D1O32_RS10215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D1O32_RS10225	COG0561	phosphatase activity
D1O32_RS10235	COG3716	PTS system mannose fructose sorbose family IID component
D1O32_RS10240	COG3715	PTS system
D1O32_RS10245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS10245	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS10255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D1O32_RS10265	COG0561	phosphatase activity
D1O32_RS10270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D1O32_RS10305	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D1O32_RS10315	COG0406	alpha-ribazole phosphatase activity
D1O32_RS10335	COG0406	alpha-ribazole phosphatase activity
D1O32_RS10345	COG0540	Belongs to the ATCase OTCase family
D1O32_RS10365	COG1316	TRANSCRIPTIONal
D1O32_RS10410	COG4464	protein tyrosine phosphatase activity
D1O32_RS10415	COG0489	protein tyrosine kinase activity
D1O32_RS10430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D1O32_RS10430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D1O32_RS10435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D1O32_RS10440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D1O32_RS10450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D1O32_RS10460	COG2070	2-Nitropropane dioxygenase
D1O32_RS10470	COG0825	malonyl-CoA metabolic process
D1O32_RS10475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D1O32_RS10480	COG0439	Biotin carboxylase
D1O32_RS10490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D1O32_RS10500	COG2855	membrane
D1O32_RS10515	COG0745	RESPONSE REGULATOR receiver
D1O32_RS10530	COG2246	polysaccharide biosynthetic process
D1O32_RS10535	COG0463	Glycosyl transferase, family 2
D1O32_RS10580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1O32_RS10580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS10580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1O32_RS10585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D1O32_RS10605	COG0544	peptidyl-prolyl cis-trans isomerase activity
D1O32_RS10615	COG3022	response to hydroperoxide
D1O32_RS10620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D1O32_RS10630	COG0561	phosphatase activity
D1O32_RS10665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D1O32_RS10695	COG1490	D-aminoacyl-tRNA deacylase activity
D1O32_RS10700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D1O32_RS10715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D1O32_RS10725	COG0516	GMP reductase activity
D1O32_RS10725	COG0517	IMP dehydrogenase activity
D1O32_RS10735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D1O32_RS10745	COG2359	stage V sporulation protein S
D1O32_RS10750	COG1692	metallophosphoesterase
D1O32_RS10760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D1O32_RS10765	COG1546	Belongs to the CinA family
D1O32_RS10765	COG1058	Belongs to the CinA family
D1O32_RS10770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D1O32_RS10780	COG0733	neurotransmitter:sodium symporter activity
D1O32_RS10785	COG1454	alcohol dehydrogenase
D1O32_RS10790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D1O32_RS10800	COG0542	response to heat
D1O32_RS10835	COG1846	Transcriptional regulator
D1O32_RS10905	COG0438	transferase activity, transferring glycosyl groups
D1O32_RS10915	COG1215	transferase activity, transferring glycosyl groups
D1O32_RS10920	COG0438	transferase activity, transferring glycosyl groups
D1O32_RS10930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D1O32_RS10935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D1O32_RS10970	COG1902	pentaerythritol trinitrate reductase activity
D1O32_RS10970	COG0446	pyridine nucleotide-disulphide oxidoreductase
D1O32_RS10985	COG2207	Transcriptional regulator
D1O32_RS11055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D1O32_RS11065	COG0058	SHG alpha-glucan phosphorylase activity
D1O32_RS11075	COG2508	Transcriptional regulator
D1O32_RS11080	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D1O32_RS11095	COG0745	RESPONSE REGULATOR receiver
D1O32_RS11100	COG0772	Belongs to the SEDS family
D1O32_RS11105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D1O32_RS11110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D1O32_RS11120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D1O32_RS11130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1O32_RS11140	COG0564	pseudouridine synthase activity
D1O32_RS11145	COG2217	Heavy metal translocating P-type atpase
D1O32_RS11165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D1O32_RS11170	COG2309	aminopeptidase activity
D1O32_RS11185	COG0772	Belongs to the SEDS family
D1O32_RS11195	COG0564	pseudouridine synthase activity
D1O32_RS11210	COG5001	Diguanylate cyclase
D1O32_RS11225	COG0180	Tryptophanyl-tRNA synthetase
D1O32_RS11240	COG0251	oxidation-reduction process
D1O32_RS11245	COG1752	Esterase of the alpha-beta hydrolase superfamily
D1O32_RS11260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1O32_RS11275	COG0519	Catalyzes the synthesis of GMP from XMP
D1O32_RS11280	COG3394	polysaccharide catabolic process
D1O32_RS11305	COG4464	protein tyrosine phosphatase activity
D1O32_RS11315	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS11320	COG0493	'glutamate synthase
D1O32_RS11325	COG0069	glutamate synthase activity
D1O32_RS11325	COG0067	glutamate synthase
D1O32_RS11325	COG0070	glutamate synthase
D1O32_RS11330	COG4869	propanediol catabolic process
D1O32_RS11350	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS11365	COG0101	tRNA pseudouridine synthase activity
D1O32_RS11370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D1O32_RS11375	COG1122	ATPase activity
D1O32_RS11385	COG0203	ribosomal protein L17
D1O32_RS11390	COG0202	RNA polymerase activity
D1O32_RS11395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D1O32_RS11400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D1O32_RS11405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D1O32_RS11410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D1O32_RS11415	COG0024	Methionine aminopeptidase
D1O32_RS11420	COG0201	protein transport
D1O32_RS11425	COG0200	Binds to the 23S rRNA
D1O32_RS11430	COG1841	ribosomal large subunit assembly
D1O32_RS11440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D1O32_RS11445	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D1O32_RS11450	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D1O32_RS11455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D1O32_RS11470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D1O32_RS11475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D1O32_RS11490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D1O32_RS11495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D1O32_RS11500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D1O32_RS11505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D1O32_RS11510	COG0089	rRNA binding
D1O32_RS11525	COG0051	transcription antitermination factor activity, RNA binding
D1O32_RS11545	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1O32_RS11550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D1O32_RS11555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D1O32_RS11560	COG0049	tRNA binding
D1O32_RS11565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D1O32_RS11570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D1O32_RS11580	COG2813	Specifically methylates the guanine in position
D1O32_RS11585	COG0222	ribosome binding
D1O32_RS11595	COG0081	regulation of translation
D1O32_RS11600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D1O32_RS11610	COG0126	phosphoglycerate kinase activity
D1O32_RS11620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D1O32_RS11625	COG0789	Transcriptional regulator
D1O32_RS11630	COG0789	Transcriptional regulator
D1O32_RS11640	COG0028	Belongs to the TPP enzyme family
D1O32_RS11645	COG0129	dihydroxy-acid dehydratase activity
D1O32_RS11650	COG0473	3-isopropylmalate dehydrogenase activity
D1O32_RS11655	COG0066	3-isopropylmalate dehydratase activity
D1O32_RS11660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D1O32_RS11675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D1O32_RS11680	COG1181	Belongs to the D-alanine--D-alanine ligase family
D1O32_RS11690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D1O32_RS11705	COG2011	ABC-type metal ion transport system permease component
D1O32_RS11715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D1O32_RS11720	COG1464	Belongs to the NlpA lipoprotein family
D1O32_RS11740	COG1660	Displays ATPase and GTPase activities
D1O32_RS11745	COG0492	ferredoxin-NADP+ reductase activity
D1O32_RS11750	COG0546	phosphoglycolate phosphatase activity
D1O32_RS11755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D1O32_RS11760	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D1O32_RS11765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D1O32_RS11770	COG0617	tRNA 3'-terminal CCA addition
D1O32_RS11775	COG0556	nucleotide-excision repair
D1O32_RS11780	COG0793	Belongs to the peptidase S41A family
D1O32_RS11820	COG0534	Mate efflux family protein
D1O32_RS11840	COG0546	phosphoglycolate phosphatase activity
D1O32_RS11850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D1O32_RS11855	COG1592	Rubrerythrin
D1O32_RS11875	COG1309	transcriptional regulator
D1O32_RS11885	COG1472	Belongs to the glycosyl hydrolase 3 family
D1O32_RS11890	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS11895	COG2971	BadF BadG BcrA BcrD
D1O32_RS11900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS11925	COG0789	Transcriptional regulator
D1O32_RS11965	COG1136	(ABC) transporter
D1O32_RS11970	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
D1O32_RS12015	COG1131	(ABC) transporter
D1O32_RS12085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D1O32_RS12090	COG0557	exoribonuclease II activity
D1O32_RS12095	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D1O32_RS12100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D1O32_RS12110	COG0561	phosphatase activity
D1O32_RS12120	COG0739	heme binding
D1O32_RS12125	COG2385	sporulation resulting in formation of a cellular spore
D1O32_RS12200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D1O32_RS12205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D1O32_RS12210	COG2155	Conserved Protein
D1O32_RS12220	COG0813	purine-nucleoside phosphorylase activity
D1O32_RS12250	COG0367	asparagine synthase
D1O32_RS12260	COG0710	3-dehydroquinate dehydratase activity
D1O32_RS12265	COG1394	ATPase activity, coupled to movement of substances
D1O32_RS12275	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
D1O32_RS12295	COG1269	ATP hydrolysis coupled proton transport
D1O32_RS12320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D1O32_RS12335	COG1876	peptidase activity
D1O32_RS12340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D1O32_RS12340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D1O32_RS12395	COG1307	EDD domain protein, DegV family
D1O32_RS12430	COG0860	N-Acetylmuramoyl-L-alanine amidase
D1O32_RS12450	COG0024	Methionine aminopeptidase
D1O32_RS12465	COG1131	(ABC) transporter
D1O32_RS12480	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS12485	COG2190	(PTS) system
D1O32_RS12485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS12485	COG1263	PTS System
D1O32_RS12490	COG3711	transcriptional antiterminator
D1O32_RS12500	COG1882	Formate acetyltransferase
D1O32_RS12515	COG1349	DNA-binding transcription factor activity
D1O32_RS12520	COG3343	RNA polymerase activity
D1O32_RS12525	COG0018	arginyl-trna synthetase
D1O32_RS12530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D1O32_RS12540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1O32_RS12585	COG1842	Phage shock protein A
D1O32_RS12590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1O32_RS12600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D1O32_RS12600	COG0517	IMP dehydrogenase activity
D1O32_RS12610	COG3414	Phosphotransferase system galactitol-specific IIB component
D1O32_RS12615	COG3775	system Galactitol-specific IIC component
D1O32_RS12635	COG0038	chloride channel
D1O32_RS12640	COG1802	Transcriptional regulator
D1O32_RS12645	COG0473	3-isopropylmalate dehydrogenase activity
D1O32_RS12650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D1O32_RS12655	COG1363	Peptidase, m42
D1O32_RS12660	COG4608	Belongs to the ABC transporter superfamily
D1O32_RS12665	COG0444	Belongs to the ABC transporter superfamily
D1O32_RS12670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1O32_RS12680	COG0747	negative chemotaxis
D1O32_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS12700	COG0488	(ABC) transporter
D1O32_RS12705	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS12715	COG2207	Transcriptional regulator
D1O32_RS12725	COG0583	DNA-binding transcription factor activity
D1O32_RS12730	COG1115	amino acid carrier protein
D1O32_RS12750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS12755	COG2188	Transcriptional regulator
D1O32_RS12760	COG1486	melibiose metabolic process
D1O32_RS12770	COG0622	Phosphoesterase
D1O32_RS12775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D1O32_RS12790	COG0281	malic enzyme
D1O32_RS12795	COG0352	thiamine-phosphate diphosphorylase activity
D1O32_RS12795	COG0351	phosphomethylpyrimidine kinase
D1O32_RS12820	COG1132	(ABC) transporter
D1O32_RS12825	COG1132	(ABC) transporter
D1O32_RS12830	COG0583	DNA-binding transcription factor activity
D1O32_RS12840	COG2186	Transcriptional regulator
D1O32_RS12855	COG0534	Mate efflux family protein
D1O32_RS12880	COG0523	cobalamin synthesis protein
D1O32_RS12885	COG0577	efflux transmembrane transporter activity
D1O32_RS12885	COG1136	(ABC) transporter
D1O32_RS12930	COG1316	TRANSCRIPTIONal
D1O32_RS12945	COG1396	sequence-specific DNA binding
D1O32_RS12960	COG0789	Transcriptional regulator
D1O32_RS12960	COG4978	Transcriptional regulator
D1O32_RS12980	COG1368	sulfuric ester hydrolase activity
D1O32_RS13020	COG0406	alpha-ribazole phosphatase activity
D1O32_RS13025	COG0534	Mate efflux family protein
D1O32_RS13035	COG1373	ATPase (AAA superfamily
D1O32_RS13040	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS13055	COG0655	NAD(P)H dehydrogenase (quinone) activity
D1O32_RS13060	COG0789	Transcriptional regulator
D1O32_RS13070	COG0789	Transcriptional regulator
D1O32_RS13080	COG1979	alcohol dehydrogenase
D1O32_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS13105	COG0583	DNA-binding transcription factor activity
D1O32_RS13135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D1O32_RS13145	COG0561	phosphatase activity
D1O32_RS13150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D1O32_RS13170	COG5002	protein histidine kinase activity
D1O32_RS13175	COG0745	RESPONSE REGULATOR receiver
D1O32_RS13185	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS13205	COG2226	methyltransferase
D1O32_RS13225	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS13240	COG1595	DNA-templated transcription, initiation
D1O32_RS13265	COG1309	transcriptional regulator
D1O32_RS13270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D1O32_RS13280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D1O32_RS13285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D1O32_RS13305	COG2890	protein-(glutamine-N5) methyltransferase activity
D1O32_RS13310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D1O32_RS13365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1O32_RS13370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D1O32_RS13385	COG3715	PTS system
D1O32_RS13400	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D1O32_RS13400	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D1O32_RS13405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D1O32_RS13465	COG1435	thymidine kinase activity
D1O32_RS13470	COG0305	Participates in initiation and elongation during chromosome replication
D1O32_RS13475	COG0359	binds to the 23S rRNA
D1O32_RS13480	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D1O32_RS13490	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS13495	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS13500	COG1475	DNA binding
D1O32_RS13505	COG1192	Involved in chromosome partitioning
D1O32_RS13510	COG0688	phosphatidylethanolamine metabolic process
D1O32_RS13515	COG1183	phosphatidylcholine synthase activity
D1O32_RS13520	COG0602	queuosine metabolic process
D1O32_RS13535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D1O32_RS13535	COG1328	CTP reductase activity
D1O32_RS13540	COG1272	protein, Hemolysin III
D1O32_RS13545	COG0756	dUTP diphosphatase activity
D1O32_RS13575	COG0561	phosphatase activity
D1O32_RS13595	COG0561	phosphatase activity
D1O32_RS13600	COG1475	DNA binding
D1O32_RS13605	COG0357	Ribosomal RNA small subunit methyltransferase G
D1O32_RS13625	COG0084	hydrolase, TatD family'
D1O32_RS13645	COG3279	Response regulator of the LytR AlgR family
D1O32_RS13675	COG1131	(ABC) transporter
D1O32_RS13690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1O32_RS13695	COG1854	S-ribosylhomocysteine lyase activity
D1O32_RS13730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D1O32_RS13735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D1O32_RS13750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D1O32_RS13770	COG1924	4 iron, 4 sulfur cluster binding
D1O32_RS13775	COG1846	Transcriptional regulator
D1O32_RS13780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D1O32_RS13810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D1O32_RS13815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D1O32_RS13820	COG1774	PSP1 C-terminal conserved region
D1O32_RS13825	COG0470	DNA polymerase III
D1O32_RS13840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D1O32_RS13860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D1O32_RS13870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D1O32_RS13875	COG0187	DNA topoisomerase II activity
D1O32_RS13880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D1O32_RS13890	COG0592	DNA-directed DNA polymerase activity
D1O32_RS13895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D1O32_RS13900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D1O32_RS13910	COG0706	membrane insertase activity
D1O32_RS13925	COG0450	alkyl hydroperoxide reductase
D1O32_RS13935	COG2720	vancomycin resistance protein
D1O32_RS13960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D1O32_RS13975	COG1401	restriction endodeoxyribonuclease activity
D1O32_RS14025	COG3177	Filamentation induced by cAMP protein fic
D1O32_RS14030	COG0366	Alpha amylase catalytic
D1O32_RS14040	COG0561	phosphatase activity
D1O32_RS14045	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS14055	COG0534	Mate efflux family protein
D1O32_RS14060	COG0583	DNA-binding transcription factor activity
D1O32_RS14070	COG3716	PTS system mannose fructose sorbose family IID component
D1O32_RS14075	COG3715	PTS system
D1O32_RS14085	COG3711	transcriptional antiterminator
D1O32_RS14090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1O32_RS14090	COG1263	PTS System
D1O32_RS14090	COG2190	(PTS) system
D1O32_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
D1O32_RS14140	COG2205	protein histidine kinase activity
D1O32_RS14140	COG0784	Response regulator, receiver
D1O32_RS14160	COG2801	Transposase and inactivated derivatives
D1O32_RS14180	COG0297	glycogen (starch) synthase activity
D1O32_RS14185	COG1918	ferrous iron import across plasma membrane
D1O32_RS14185	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D1O32_RS14190	COG0577	efflux transmembrane transporter activity
D1O32_RS14195	COG1136	(ABC) transporter
D1O32_RS14205	COG3938	Belongs to the proline racemase family
D1O32_RS14220	COG1522	sequence-specific DNA binding
D1O32_RS14225	COG0534	Mate efflux family protein
D1O32_RS14230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D1O32_RS14235	COG1733	regulation of RNA biosynthetic process
D1O32_RS14275	COG1737	Transcriptional regulator
D1O32_RS14295	COG0561	phosphatase activity
D1O32_RS14310	COG1393	Belongs to the ArsC family
D1O32_RS14320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D1O32_RS14325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D1O32_RS14330	COG0019	diaminopimelate decarboxylase activity
D1O32_RS14375	COG0375	protein maturation
D1O32_RS14380	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D1O32_RS14385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D1O32_RS14390	COG0583	DNA-binding transcription factor activity
D1O32_RS14420	COG0784	Response regulator, receiver
D1O32_RS14420	COG2205	protein histidine kinase activity
D1O32_RS14435	COG3437	response regulator, receiver
D1O32_RS14460	COG2357	RelA SpoT domain protein
D1O32_RS14475	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS14485	COG0561	phosphatase activity
D1O32_RS14515	COG0360	Binds together with S18 to 16S ribosomal RNA
D1O32_RS14525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D1O32_RS14535	COG3620	sequence-specific DNA binding
D1O32_RS14545	COG0534	Mate efflux family protein
D1O32_RS14585	COG0582	viral genome integration into host DNA
D1O32_RS14590	COG1733	regulation of RNA biosynthetic process
D1O32_RS14610	COG1846	Transcriptional regulator
D1O32_RS14625	COG1959	2 iron, 2 sulfur cluster binding
D1O32_RS14630	COG2033	superoxide reductase activity
D1O32_RS14665	COG0656	L-ascorbic acid biosynthetic process
D1O32_RS14680	COG2723	6-phospho-beta-galactosidase activity
D1O32_RS14685	COG1609	Transcriptional regulator
D1O32_RS14690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1O32_RS14705	COG0583	DNA-binding transcription factor activity
D1O32_RS14710	COG4221	oxidoreductase activity
D1O32_RS14715	COG0667	Aldo Keto reductase
D1O32_RS14720	COG1073	alpha beta
D1O32_RS14745	COG1595	DNA-templated transcription, initiation