locus-tag	class	description
CTC_RS00005	COG0542	response to heat
CTC_RS00075	COG2816	NAD+ diphosphatase activity
CTC_RS00090	COG3829	transcription factor binding
CTC_RS00115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTC_RS00145	COG0590	tRNA wobble adenosine to inosine editing
CTC_RS00155	COG1309	transcriptional regulator
CTC_RS00195	COG5002	protein histidine kinase activity
CTC_RS00205	COG1827	regulation of RNA biosynthetic process
CTC_RS00240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTC_RS00245	COG0187	DNA topoisomerase II activity
CTC_RS00265	COG0592	DNA-directed DNA polymerase activity
CTC_RS00295	COG1847	R3H domain protein
CTC_RS00320	COG1192	Involved in chromosome partitioning
CTC_RS00325	COG1475	DNA binding
CTC_RS00340	COG0628	permease
CTC_RS00345	COG0668	transmembrane transport
CTC_RS00355	COG0360	Binds together with S18 to 16S ribosomal RNA
CTC_RS00365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTC_RS00380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CTC_RS00390	COG1067	ATP-dependent peptidase activity
CTC_RS00390	COG0470	DNA polymerase III
CTC_RS00395	COG0305	Participates in initiation and elongation during chromosome replication
CTC_RS00420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTC_RS00420	COG0644	oxidoreductase
CTC_RS00435	COG2081	HI0933 family
CTC_RS00505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTC_RS00510	COG1028	Short-chain dehydrogenase reductase Sdr
CTC_RS00515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTC_RS00530	COG0439	Biotin carboxylase
CTC_RS00545	COG2801	Transposase and inactivated derivatives
CTC_RS00585	COG0785	Cytochrome C biogenesis protein
CTC_RS00590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTC_RS00635	COG1187	pseudouridine synthase activity
CTC_RS00650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTC_RS00655	COG2205	protein histidine kinase activity
CTC_RS00665	COG1131	(ABC) transporter
CTC_RS00670	COG0745	RESPONSE REGULATOR receiver
CTC_RS00695	COG0653	protein targeting
CTC_RS00710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CTC_RS00725	COG0174	glutamine synthetase
CTC_RS00750	COG2801	Transposase and inactivated derivatives
CTC_RS00755	COG3949	Membrane
CTC_RS00765	COG1242	4 iron, 4 sulfur cluster binding
CTC_RS00780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTC_RS00800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTC_RS00805	COG2088	sporulation resulting in formation of a cellular spore
CTC_RS00820	COG0745	RESPONSE REGULATOR receiver
CTC_RS00825	COG3850	Histidine kinase
CTC_RS00825	COG5002	protein histidine kinase activity
CTC_RS00830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTC_RS00840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTC_RS00850	COG2002	toxin-antitoxin pair type II binding
CTC_RS00855	COG2244	polysaccharide biosynthetic process
CTC_RS00860	COG3956	TIGRFAM MazG family protein
CTC_RS00870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTC_RS00890	COG1098	S1 RNA binding domain
CTC_RS00930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CTC_RS00935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTC_RS00950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTC_RS01035	COG1982	Orn Lys Arg decarboxylase major
CTC_RS01045	COG3870	Protein conserved in bacteria
CTC_RS01055	COG1774	PSP1 C-terminal conserved region
CTC_RS01070	COG2801	Transposase and inactivated derivatives
CTC_RS01080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CTC_RS01085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CTC_RS01095	COG2002	toxin-antitoxin pair type II binding
CTC_RS01105	COG0726	polysaccharide deacetylase
CTC_RS01110	COG1940	carbohydrate kinase activity
CTC_RS01125	COG0251	oxidation-reduction process
CTC_RS01130	COG4193	domain, Protein
CTC_RS01150	COG2715	membrane protein required for spore maturation
CTC_RS01155	COG0700	Nucleoside recognition
CTC_RS01160	COG1131	(ABC) transporter
CTC_RS01170	COG1573	uracil-dna glycosylase
CTC_RS01180	COG0084	hydrolase, TatD family'
CTC_RS01185	COG3584	3D domain protein
CTC_RS01185	COG3583	domain protein
CTC_RS01240	COG1328	CTP reductase activity
CTC_RS01245	COG0602	queuosine metabolic process
CTC_RS01255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTC_RS01265	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS01280	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CTC_RS01330	COG1840	ABC-type Fe3 transport system, periplasmic component
CTC_RS01340	COG3842	ATPase activity
CTC_RS01350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTC_RS01365	COG2002	toxin-antitoxin pair type II binding
CTC_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTC_RS01375	COG2190	(PTS) system
CTC_RS01375	COG1263	PTS System
CTC_RS01385	COG4466	Protein conserved in bacteria
CTC_RS01395	COG4242	Belongs to the peptidase S51 family
CTC_RS01415	COG0697	spore germination
CTC_RS01440	COG2959	enzyme of heme biosynthesis
CTC_RS01470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CTC_RS01475	COG0840	transmembrane signaling receptor activity
CTC_RS01490	COG3872	metal-dependent enzyme
CTC_RS01515	COG0009	L-threonylcarbamoyladenylate synthase
CTC_RS01520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTC_RS01525	COG0698	ribose 5-phosphate isomerase
CTC_RS01540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTC_RS01545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTC_RS01550	COG0183	Belongs to the thiolase family
CTC_RS01565	COG2385	sporulation resulting in formation of a cellular spore
CTC_RS01570	COG1196	nuclear chromosome segregation
CTC_RS01570	COG0741	lytic transglycosylase activity
CTC_RS01570	COG0739	heme binding
CTC_RS01575	COG1609	Transcriptional regulator
CTC_RS01580	COG1077	Cell shape determining protein MreB Mrl
CTC_RS01590	COG0037	tRNA processing
CTC_RS01620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTC_RS01650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CTC_RS01660	COG2183	response to ionizing radiation
CTC_RS01675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CTC_RS01690	COG2357	RelA SpoT domain protein
CTC_RS01720	COG1482	cell wall glycoprotein biosynthetic process
CTC_RS01740	COG2323	membrane
CTC_RS01755	COG1183	phosphatidylcholine synthase activity
CTC_RS01760	COG0517	IMP dehydrogenase activity
CTC_RS01765	COG1597	lipid kinase activity
CTC_RS01775	COG1045	serine acetyltransferase
CTC_RS01780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTC_RS01795	COG0281	malic enzyme
CTC_RS01805	COG1704	LemA family
CTC_RS01815	COG2720	vancomycin resistance protein
CTC_RS01820	COG0714	Associated with various cellular activities
CTC_RS01845	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS01850	COG0561	phosphatase activity
CTC_RS01855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTC_RS01860	COG1307	EDD domain protein, DegV family
CTC_RS01865	COG1744	ABC transporter substrate-binding protein PnrA-like
CTC_RS01870	COG3845	ABC transporter
CTC_RS01875	COG4603	Belongs to the binding-protein-dependent transport system permease family
CTC_RS01880	COG1079	Belongs to the binding-protein-dependent transport system permease family
CTC_RS01885	COG1174	glycine betaine transport
CTC_RS01900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CTC_RS01905	COG2390	Transcriptional regulator
CTC_RS01945	COG0557	exoribonuclease II activity
CTC_RS01985	COG0745	RESPONSE REGULATOR receiver
CTC_RS01990	COG5002	protein histidine kinase activity
CTC_RS01995	COG1136	(ABC) transporter
CTC_RS02000	COG0577	efflux transmembrane transporter activity
CTC_RS02005	COG2391	methyltransferase activity
CTC_RS02015	COG2391	methyltransferase activity
CTC_RS02020	COG0583	DNA-binding transcription factor activity
CTC_RS02025	COG2391	methyltransferase activity
CTC_RS02045	COG1278	Cold shock
CTC_RS02050	COG1116	anion transmembrane transporter activity
CTC_RS02055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTC_RS02060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTC_RS02065	COG1979	alcohol dehydrogenase
CTC_RS02070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTC_RS02080	COG0745	RESPONSE REGULATOR receiver
CTC_RS02085	COG3850	Histidine kinase
CTC_RS02085	COG5002	protein histidine kinase activity
CTC_RS02100	COG2323	membrane
CTC_RS02110	COG0723	plastoquinol--plastocyanin reductase activity
CTC_RS02110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTC_RS02125	COG0116	Belongs to the methyltransferase superfamily
CTC_RS02140	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTC_RS02155	COG1132	(ABC) transporter
CTC_RS02160	COG0584	glycerophosphoryl diester phosphodiesterase
CTC_RS02225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTC_RS02230	COG3951	Flagellar rod assembly protein muramidase FlgJ
CTC_RS02230	COG1705	Flagellar rod assembly protein muramidase FlgJ
CTC_RS02265	COG0534	Mate efflux family protein
CTC_RS02290	COG1924	4 iron, 4 sulfur cluster binding
CTC_RS02295	COG2801	Transposase and inactivated derivatives
CTC_RS02305	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CTC_RS02330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CTC_RS02335	COG5002	protein histidine kinase activity
CTC_RS02345	COG0653	protein targeting
CTC_RS02405	COG0840	transmembrane signaling receptor activity
CTC_RS02410	COG2610	gluconate transmembrane transporter activity
CTC_RS02415	COG1960	acyl-CoA dehydrogenase activity
CTC_RS02420	COG4670	ketone body catabolic process
CTC_RS02425	COG1024	Enoyl-CoA hydratase
CTC_RS02430	COG1733	regulation of RNA biosynthetic process
CTC_RS02435	COG0668	transmembrane transport
CTC_RS02440	COG0427	acetyl-CoA hydrolase
CTC_RS02455	COG1136	(ABC) transporter
CTC_RS02460	COG0577	efflux transmembrane transporter activity
CTC_RS02460	COG1136	(ABC) transporter
CTC_RS02485	COG1511	domain protein
CTC_RS02510	COG0731	radical SAM domain protein
CTC_RS02510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CTC_RS02530	COG1349	DNA-binding transcription factor activity
CTC_RS02540	COG0191	fructose-bisphosphate aldolase activity
CTC_RS02550	COG3718	enzyme involved in inositol metabolism
CTC_RS02560	COG0673	inositol 2-dehydrogenase activity
CTC_RS02570	COG0673	inositol 2-dehydrogenase activity
CTC_RS02575	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTC_RS02585	COG2801	Transposase and inactivated derivatives
CTC_RS02610	COG2247	cell wall binding repeat
CTC_RS02610	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS02650	COG0705	Rhomboid family
CTC_RS02650	COG0457	Tetratricopeptide repeat
CTC_RS02655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTC_RS02685	COG1368	sulfuric ester hydrolase activity
CTC_RS02690	COG3442	glutamine amidotransferase
CTC_RS02695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTC_RS02765	COG0658	competence protein
CTC_RS02765	COG2333	competence protein COMEC
CTC_RS02785	COG1595	DNA-templated transcription, initiation
CTC_RS02795	COG3829	transcription factor binding
CTC_RS02800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTC_RS02805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTC_RS02810	COG0765	amino acid transport
CTC_RS02815	COG1126	abc transporter atp-binding protein
CTC_RS02830	COG1115	amino acid carrier protein
CTC_RS02840	COG1757	Na H antiporter
CTC_RS02845	COG1522	sequence-specific DNA binding
CTC_RS02855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTC_RS02870	COG0693	protein deglycase activity
CTC_RS02880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTC_RS02885	COG1959	2 iron, 2 sulfur cluster binding
CTC_RS02905	COG0419	ATPase involved in DNA repair
CTC_RS02910	COG0488	(ABC) transporter
CTC_RS02915	COG1228	amidohydrolase
CTC_RS02920	COG1228	amidohydrolase
CTC_RS02925	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CTC_RS02935	COG1272	protein, Hemolysin III
CTC_RS02945	COG0488	(ABC) transporter
CTC_RS02955	COG2032	superoxide dismutase activity
CTC_RS02990	COG0745	RESPONSE REGULATOR receiver
CTC_RS02995	COG3850	Histidine kinase
CTC_RS02995	COG5002	protein histidine kinase activity
CTC_RS03005	COG1695	Transcriptional regulator
CTC_RS03015	COG0534	Mate efflux family protein
CTC_RS03025	COG1607	acyl-coa hydrolase
CTC_RS03040	COG1595	DNA-templated transcription, initiation
CTC_RS03050	COG3279	Response regulator of the LytR AlgR family
CTC_RS03065	COG3591	Belongs to the peptidase S1B family
CTC_RS03085	COG1595	DNA-templated transcription, initiation
CTC_RS03110	COG1131	(ABC) transporter
CTC_RS03140	COG1357	PFAM Pentapeptide repeats (8 copies)
CTC_RS03150	COG1131	(ABC) transporter
CTC_RS03185	COG2207	Transcriptional regulator
CTC_RS03185	COG3708	Transcriptional regulator
CTC_RS03190	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CTC_RS03225	COG1131	(ABC) transporter
CTC_RS03245	COG2996	Protein conserved in bacteria
CTC_RS03255	COG3481	metal-dependent phosphohydrolase, HD sub domain
CTC_RS03260	COG1376	ErfK ybiS ycfS ynhG family protein
CTC_RS03280	COG1785	Belongs to the alkaline phosphatase family
CTC_RS03285	COG2059	Chromate
CTC_RS03290	COG2059	Chromate
CTC_RS03315	COG1728	Protein conserved in bacteria
CTC_RS03345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTC_RS03345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTC_RS03365	COG0617	tRNA 3'-terminal CCA addition
CTC_RS03370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTC_RS03375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTC_RS03375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTC_RS03405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTC_RS03425	COG1595	DNA-templated transcription, initiation
CTC_RS03455	COG0210	DNA helicase
CTC_RS03465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTC_RS03485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTC_RS03490	COG1335	isochorismatase
CTC_RS03495	COG2610	gluconate transmembrane transporter activity
CTC_RS03500	COG1929	Belongs to the glycerate kinase type-1 family
CTC_RS03505	COG0840	transmembrane signaling receptor activity
CTC_RS03520	COG2030	dehydratase
CTC_RS03525	COG3290	protein histidine kinase activity
CTC_RS03525	COG3829	transcription factor binding
CTC_RS03535	COG2610	gluconate transmembrane transporter activity
CTC_RS03540	COG1960	acyl-CoA dehydrogenase activity
CTC_RS03545	COG2086	electron transfer activity
CTC_RS03550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CTC_RS03555	COG1074	ATP-dependent DNA helicase activity
CTC_RS03560	COG5002	protein histidine kinase activity
CTC_RS03565	COG5002	protein histidine kinase activity
CTC_RS03570	COG0406	alpha-ribazole phosphatase activity
CTC_RS03575	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CTC_RS03595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTC_RS03630	COG1587	Uroporphyrinogen-III synthase
CTC_RS03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTC_RS03635	COG0113	porphobilinogen synthase activity
CTC_RS03750	COG1129	ABC transporter
CTC_RS03805	COG0714	Associated with various cellular activities
CTC_RS03825	COG1657	PFAM Prenyltransferase squalene oxidase
CTC_RS03880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTC_RS03885	COG4667	esterase of the alpha-beta hydrolase superfamily
CTC_RS03900	COG1120	ATPase activity
CTC_RS03905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTC_RS03910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTC_RS03920	COG1114	Component of the transport system for branched-chain amino acids
CTC_RS03925	COG2801	Transposase and inactivated derivatives
CTC_RS03935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTC_RS03940	COG5434	Belongs to the glycosyl hydrolase 28 family
CTC_RS03940	COG4632	Exopolysaccharide biosynthesis protein
CTC_RS03950	COG1994	Peptidase M50
CTC_RS03970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CTC_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
CTC_RS04005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTC_RS04030	COG2002	toxin-antitoxin pair type II binding
CTC_RS04045	COG2267	carboxylic ester hydrolase activity
CTC_RS04060	COG0493	'glutamate synthase
CTC_RS04080	COG0733	neurotransmitter:sodium symporter activity
CTC_RS04085	COG1802	Transcriptional regulator
CTC_RS04090	COG0658	competence protein
CTC_RS04090	COG2333	competence protein COMEC
CTC_RS04100	COG1794	racemase activity, acting on amino acids and derivatives
CTC_RS04105	COG1027	Aspartate ammonia-lyase
CTC_RS04110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CTC_RS04115	COG1773	rubredoxin
CTC_RS04115	COG1592	Rubrerythrin
CTC_RS04120	COG0561	phosphatase activity
CTC_RS04135	COG2801	Transposase and inactivated derivatives
CTC_RS04170	COG5298	Protein conserved in bacteria
CTC_RS04175	COG1215	transferase activity, transferring glycosyl groups
CTC_RS04195	COG3314	Sporulation integral membrane protein YlbJ
CTC_RS04210	COG1285	pathogenesis
CTC_RS04215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTC_RS04220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTC_RS04230	COG3192	ethanolamine utilization protein
CTC_RS04245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTC_RS04285	COG0840	transmembrane signaling receptor activity
CTC_RS04290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTC_RS04305	COG4211	Belongs to the binding-protein-dependent transport system permease family
CTC_RS04310	COG1609	Transcriptional regulator
CTC_RS04315	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CTC_RS04325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTC_RS04330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTC_RS04335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTC_RS04345	COG3546	catalase activity
CTC_RS04370	COG5002	protein histidine kinase activity
CTC_RS04375	COG1937	Protein conserved in bacteria
CTC_RS04380	COG2217	Heavy metal translocating P-type atpase
CTC_RS04435	COG1307	EDD domain protein, DegV family
CTC_RS04450	COG0840	transmembrane signaling receptor activity
CTC_RS04475	COG0450	alkyl hydroperoxide reductase
CTC_RS04510	COG1533	DNA photolyase activity
CTC_RS04515	COG1757	Na H antiporter
CTC_RS04520	COG1234	tRNA 3'-trailer cleavage
CTC_RS04535	COG1609	Transcriptional regulator
CTC_RS04540	COG1129	ABC transporter
CTC_RS04545	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTC_RS04550	COG1879	ABC-type sugar transport system periplasmic component
CTC_RS04555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTC_RS04555	COG0517	IMP dehydrogenase activity
CTC_RS04560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTC_RS04580	COG1917	Cupin 2, conserved barrel domain protein
CTC_RS04580	COG4977	sequence-specific DNA binding
CTC_RS04585	COG2375	cellular response to nickel ion
CTC_RS04585	COG1132	(ABC) transporter
CTC_RS04590	COG1132	(ABC) transporter
CTC_RS04595	COG0110	maltose O-acetyltransferase activity
CTC_RS04620	COG0577	efflux transmembrane transporter activity
CTC_RS04620	COG1136	(ABC) transporter
CTC_RS04635	COG1395	domain, Protein
CTC_RS04640	COG2116	formate transmembrane transporter activity
CTC_RS04645	COG0840	transmembrane signaling receptor activity
CTC_RS04650	COG2508	Transcriptional regulator
CTC_RS04655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTC_RS04660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTC_RS04670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTC_RS04675	COG0543	2 iron, 2 sulfur cluster binding
CTC_RS04680	COG0167	dihydroorotate dehydrogenase activity
CTC_RS04705	COG2972	Histidine kinase
CTC_RS04710	COG2197	response regulator
CTC_RS04715	COG1882	Formate acetyltransferase
CTC_RS04720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTC_RS04725	COG3689	TIGRFAM TIGR03943 family protein
CTC_RS04730	COG0701	Predicted permease
CTC_RS04745	COG0840	transmembrane signaling receptor activity
CTC_RS04750	COG2390	Transcriptional regulator
CTC_RS04800	COG1120	ATPase activity
CTC_RS04805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTC_RS04830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTC_RS04835	COG1120	ATPase activity
CTC_RS04850	COG1937	Protein conserved in bacteria
CTC_RS04855	COG1331	Highly conserved protein containing a thioredoxin domain
CTC_RS04890	COG2186	Transcriptional regulator
CTC_RS04895	COG1620	l-lactate permease
CTC_RS04900	COG2086	electron transfer activity
CTC_RS04905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CTC_RS04910	COG0277	FAD linked oxidase domain protein
CTC_RS04920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CTC_RS04925	COG0697	spore germination
CTC_RS04930	COG1686	Belongs to the peptidase S11 family
CTC_RS04945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CTC_RS04950	COG0210	DNA helicase
CTC_RS04960	COG0564	pseudouridine synthase activity
CTC_RS04965	COG2244	polysaccharide biosynthetic process
CTC_RS04970	COG2244	polysaccharide biosynthetic process
CTC_RS04990	COG1032	radical SAM domain protein
CTC_RS05000	COG1269	ATP hydrolysis coupled proton transport
CTC_RS05005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CTC_RS05035	COG1394	ATPase activity, coupled to movement of substances
CTC_RS05050	COG0426	domain, Protein
CTC_RS05060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTC_RS05065	COG1494	fructose-1,6-bisphosphatase
CTC_RS05070	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS05080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTC_RS05085	COG1362	aminopeptidase activity
CTC_RS05090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CTC_RS05110	COG1937	Protein conserved in bacteria
CTC_RS05120	COG2966	Psort location CytoplasmicMembrane, score
CTC_RS05125	COG4656	Part of a membrane complex involved in electron transport
CTC_RS05130	COG4658	electron transport chain
CTC_RS05135	COG4659	FMN binding
CTC_RS05140	COG4660	Part of a membrane complex involved in electron transport
CTC_RS05145	COG4657	Part of a membrane complex involved in electron transport
CTC_RS05150	COG1245	4Fe-4S binding domain
CTC_RS05150	COG2878	Part of a membrane complex involved in electron transport
CTC_RS05170	COG1368	sulfuric ester hydrolase activity
CTC_RS05175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTC_RS05195	COG3830	Belongs to the UPF0237 family
CTC_RS05205	COG0494	nUDIX hydrolase
CTC_RS05220	COG2766	serine protein kinase
CTC_RS05225	COG2718	Belongs to the UPF0229 family
CTC_RS05230	COG2719	SpoVR family
CTC_RS05250	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CTC_RS05260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTC_RS05265	COG1959	2 iron, 2 sulfur cluster binding
CTC_RS05290	COG0628	permease
CTC_RS05300	COG4472	Bacterial protein of unknown function (DUF965)
CTC_RS05315	COG0735	belongs to the Fur family
CTC_RS05320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CTC_RS05330	COG1217	gtp-binding protein TYPA
CTC_RS05335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTC_RS05340	COG4122	O-methyltransferase activity
CTC_RS05345	COG0826	peptidase U32
CTC_RS05410	COG5377	YqaJ viral recombinase family
CTC_RS05415	COG3723	Recombinational DNA repair protein, rece pathway
CTC_RS05445	COG0783	Belongs to the Dps family
CTC_RS05495	COG5484	DNA packaging
CTC_RS05495	COG3728	DNA packaging
CTC_RS05685	COG2176	DNA-directed DNA polymerase activity
CTC_RS05710	COG0849	cell division
CTC_RS05715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTC_RS05725	COG1191	sigma factor activity
CTC_RS05730	COG1191	sigma factor activity
CTC_RS05735	COG1873	PFAM PRC-barrel domain
CTC_RS05745	COG0745	RESPONSE REGULATOR receiver
CTC_RS05750	COG5002	protein histidine kinase activity
CTC_RS05755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTC_RS05760	COG0573	inorganic phosphate transmembrane transporter activity
CTC_RS05765	COG0581	inorganic phosphate transmembrane transporter activity
CTC_RS05790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CTC_RS05840	COG1518	maintenance of DNA repeat elements
CTC_RS05845	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CTC_RS05855	COG2267	carboxylic ester hydrolase activity
CTC_RS05875	COG2873	o-acetylhomoserine
CTC_RS05885	COG5278	phosphoserine phosphatase activity
CTC_RS05885	COG0840	transmembrane signaling receptor activity
CTC_RS05895	COG3326	Membrane
CTC_RS05915	COG4187	Peptidase family M20/M25/M40
CTC_RS05925	COG0488	(ABC) transporter
CTC_RS05960	COG0789	Transcriptional regulator
CTC_RS05970	COG1349	DNA-binding transcription factor activity
CTC_RS05975	COG1115	amino acid carrier protein
CTC_RS05980	COG2271	Major facilitator Superfamily
CTC_RS05990	COG2391	methyltransferase activity
CTC_RS06000	COG2391	methyltransferase activity
CTC_RS06005	COG0583	DNA-binding transcription factor activity
CTC_RS06010	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTC_RS06015	COG2391	methyltransferase activity
CTC_RS06020	COG3858	chitin binding
CTC_RS06020	COG1388	LysM domain
CTC_RS06025	COG1393	Belongs to the ArsC family
CTC_RS06030	COG1592	Rubrerythrin
CTC_RS06035	COG0475	glutathione-regulated potassium exporter activity
CTC_RS06040	COG3583	domain protein
CTC_RS06040	COG3584	3D domain protein
CTC_RS06045	COG0726	polysaccharide deacetylase
CTC_RS06050	COG1115	amino acid carrier protein
CTC_RS06065	COG0733	neurotransmitter:sodium symporter activity
CTC_RS06070	COG1376	ErfK ybiS ycfS ynhG family protein
CTC_RS06090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTC_RS06105	COG4988	ABC transporter
CTC_RS06110	COG1132	(ABC) transporter
CTC_RS06120	COG2247	cell wall binding repeat
CTC_RS06120	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS06130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTC_RS06135	COG0617	tRNA 3'-terminal CCA addition
CTC_RS06180	COG0840	transmembrane signaling receptor activity
CTC_RS06185	COG0583	DNA-binding transcription factor activity
CTC_RS06200	COG1561	YicC-like family, N-terminal region
CTC_RS06220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTC_RS06225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTC_RS06240	COG2738	Putative neutral zinc metallopeptidase
CTC_RS06245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTC_RS06245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTC_RS06255	COG0631	protein serine/threonine phosphatase activity
CTC_RS06260	COG2815	serine threonine protein kinase
CTC_RS06260	COG0515	serine threonine protein kinase
CTC_RS06270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTC_RS06285	COG1302	Protein conserved in bacteria
CTC_RS06290	COG1461	Dihydroxyacetone kinase
CTC_RS06295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTC_RS06300	COG0742	ribosomal rna small subunit methyltransferase
CTC_RS06320	COG3647	Membrane
CTC_RS06330	COG0280	phosphate acetyltransferase
CTC_RS06370	COG2359	stage V sporulation protein S
CTC_RS06380	COG0552	protein localization to endoplasmic reticulum
CTC_RS06390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTC_RS06395	COG0228	four-way junction DNA binding
CTC_RS06420	COG0681	Belongs to the peptidase S26 family
CTC_RS06440	COG0606	chelatase, subunit chli
CTC_RS06445	COG0758	DNA mediated transformation
CTC_RS06450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CTC_RS06485	COG4589	Belongs to the CDS family
CTC_RS06500	COG0750	zinc metalloprotease
CTC_RS06520	COG0195	Participates in both transcription termination and antitermination
CTC_RS06525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CTC_RS06545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTC_RS06555	COG0196	riboflavin kinase activity
CTC_RS06560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTC_RS06570	COG0612	Peptidase, M16
CTC_RS06580	COG0527	aspartate kinase activity
CTC_RS06585	COG0740	serine-type endopeptidase activity
CTC_RS06600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTC_RS06615	COG2359	stage V sporulation protein S
CTC_RS06620	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTC_RS06630	COG2076	Multidrug Resistance protein
CTC_RS06640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTC_RS06645	COG2155	Conserved Protein
CTC_RS06655	COG4974	Belongs to the 'phage' integrase family
CTC_RS06670	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CTC_RS06725	COG0840	transmembrane signaling receptor activity
CTC_RS06730	COG0436	Aminotransferase
CTC_RS06765	COG2081	HI0933 family
CTC_RS06770	COG1737	Transcriptional regulator
CTC_RS06775	COG1187	pseudouridine synthase activity
CTC_RS06795	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CTC_RS06815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CTC_RS06840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTC_RS06845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CTC_RS06865	COG0651	ATP synthesis coupled electron transport
CTC_RS06870	COG0651	ATP synthesis coupled electron transport
CTC_RS06875	COG0651	ATP synthesis coupled electron transport
CTC_RS06880	COG0713	ATP synthesis coupled electron transport
CTC_RS06895	COG1320	monovalent cation:proton antiporter activity
CTC_RS06905	COG1863	multisubunit Na H antiporter MnhE subunit
CTC_RS06915	COG1959	2 iron, 2 sulfur cluster binding
CTC_RS06920	COG1971	Probably functions as a manganese efflux pump
CTC_RS06940	COG2239	Acts as a magnesium transporter
CTC_RS06950	COG1464	Belongs to the NlpA lipoprotein family
CTC_RS06955	COG2011	ABC-type metal ion transport system permease component
CTC_RS06965	COG1183	phosphatidylcholine synthase activity
CTC_RS06970	COG1131	(ABC) transporter
CTC_RS06980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTC_RS06985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTC_RS06995	COG2207	Transcriptional regulator
CTC_RS07000	COG0534	Mate efflux family protein
CTC_RS07005	COG2333	competence protein COMEC
CTC_RS07005	COG0658	competence protein
CTC_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
CTC_RS07035	COG1120	ATPase activity
CTC_RS07040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTC_RS07060	COG4608	Belongs to the ABC transporter superfamily
CTC_RS07065	COG0444	Belongs to the ABC transporter superfamily
CTC_RS07080	COG0747	negative chemotaxis
CTC_RS07095	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CTC_RS07105	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CTC_RS07105	COG3976	FMN-binding domain protein
CTC_RS07130	COG0426	domain, Protein
CTC_RS07135	COG1960	acyl-CoA dehydrogenase activity
CTC_RS07150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTC_RS07155	COG2188	Transcriptional regulator
CTC_RS07160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTC_RS07165	COG4521	taurine ABC transporter
CTC_RS07170	COG1116	anion transmembrane transporter activity
CTC_RS07185	COG0222	ribosome binding
CTC_RS07200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CTC_RS07205	COG0747	negative chemotaxis
CTC_RS07215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTC_RS07220	COG0444	Belongs to the ABC transporter superfamily
CTC_RS07225	COG4608	Belongs to the ABC transporter superfamily
CTC_RS07235	COG2801	Transposase and inactivated derivatives
CTC_RS07245	COG1132	(ABC) transporter
CTC_RS07255	COG2207	Transcriptional regulator
CTC_RS07265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTC_RS07290	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CTC_RS07305	COG1136	(ABC) transporter
CTC_RS07310	COG3850	Histidine kinase
CTC_RS07310	COG5002	protein histidine kinase activity
CTC_RS07315	COG0745	RESPONSE REGULATOR receiver
CTC_RS07330	COG0659	secondary active sulfate transmembrane transporter activity
CTC_RS07380	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CTC_RS07410	COG2207	Transcriptional regulator
CTC_RS07410	COG3708	Transcriptional regulator
CTC_RS07435	COG2333	competence protein COMEC
CTC_RS07435	COG0658	competence protein
CTC_RS07445	COG1396	sequence-specific DNA binding
CTC_RS07460	COG4869	propanediol catabolic process
CTC_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
CTC_RS07465	COG1454	alcohol dehydrogenase
CTC_RS07475	COG4766	ethanolamine catabolic process
CTC_RS07480	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CTC_RS07510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTC_RS07515	COG1882	Formate acetyltransferase
CTC_RS07520	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CTC_RS07540	COG0789	Transcriptional regulator
CTC_RS07585	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CTC_RS07590	COG1518	maintenance of DNA repeat elements
CTC_RS07685	COG0076	glutamate decarboxylase activity
CTC_RS07705	COG0745	RESPONSE REGULATOR receiver
CTC_RS07725	COG1668	transmembrane transport
CTC_RS07730	COG4555	ABC transporter
CTC_RS07735	COG0840	transmembrane signaling receptor activity
CTC_RS07740	COG3976	FMN-binding domain protein
CTC_RS07740	COG1053	succinate dehydrogenase
CTC_RS07740	COG0431	NADPH-dependent FMN reductase
CTC_RS07755	COG0745	RESPONSE REGULATOR receiver
CTC_RS07770	COG1131	(ABC) transporter
CTC_RS07810	COG4086	secreted protein
CTC_RS07835	COG0840	transmembrane signaling receptor activity
CTC_RS07835	COG5278	phosphoserine phosphatase activity
CTC_RS07840	COG0733	neurotransmitter:sodium symporter activity
CTC_RS07850	COG5278	phosphoserine phosphatase activity
CTC_RS07850	COG0840	transmembrane signaling receptor activity
CTC_RS07865	COG3069	C4-dicarboxylate transmembrane transporter activity
CTC_RS07875	COG0539	negative regulation of cytoplasmic translation
CTC_RS07890	COG1053	succinate dehydrogenase
CTC_RS07900	COG3290	protein histidine kinase activity
CTC_RS07905	COG1686	Belongs to the peptidase S11 family
CTC_RS07915	COG3874	Sporulation protein YtfJ
CTC_RS07930	COG1686	Belongs to the peptidase S11 family
CTC_RS07940	COG4974	Belongs to the 'phage' integrase family
CTC_RS07965	COG0840	transmembrane signaling receptor activity
CTC_RS08155	COG4974	Belongs to the 'phage' integrase family
CTC_RS08160	COG0745	RESPONSE REGULATOR receiver
CTC_RS08165	COG0750	zinc metalloprotease
CTC_RS08170	COG0497	DNA recombination
CTC_RS08185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CTC_RS08200	COG0142	geranyltranstransferase activity
CTC_RS08205	COG1722	exodeoxyribonuclease VII activity
CTC_RS08265	COG3854	ATPases associated with a variety of cellular activities
CTC_RS08280	COG0006	proline dipeptidase activity
CTC_RS08325	COG4968	Prepilin-type N-terminal cleavage methylation domain
CTC_RS08335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTC_RS08360	COG5599	Phosphatase
CTC_RS08365	COG0708	Exodeoxyribonuclease III
CTC_RS08370	COG2233	PERMEase
CTC_RS08375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CTC_RS08380	COG0564	pseudouridine synthase activity
CTC_RS08390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTC_RS08400	COG1605	Chorismate mutase
CTC_RS08400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CTC_RS08405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTC_RS08415	COG3599	regulation of cell shape
CTC_RS08435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CTC_RS08445	COG3856	small basic protein
CTC_RS08460	COG0772	Belongs to the SEDS family
CTC_RS08470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTC_RS08480	COG0768	penicillin binding
CTC_RS08500	COG0569	domain protein
CTC_RS08500	COG0475	glutathione-regulated potassium exporter activity
CTC_RS08510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTC_RS08515	COG4978	Transcriptional regulator
CTC_RS08515	COG0789	Transcriptional regulator
CTC_RS08520	COG0012	GTP binding
CTC_RS08525	COG1067	ATP-dependent peptidase activity
CTC_RS08535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTC_RS08550	COG4786	Flagellar basal body rod
CTC_RS08555	COG4786	Flagellar basal body rod
CTC_RS08570	COG1191	sigma factor activity
CTC_RS08580	COG0455	bacterial-type flagellum organization
CTC_RS08585	COG1419	protein localization to endoplasmic reticulum
CTC_RS08590	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CTC_RS08605	COG1338	Plays a role in the flagellum-specific transport system
CTC_RS08630	COG1582	Flagellar protein (FlbD)
CTC_RS08635	COG4786	Flagellar basal body rod
CTC_RS08645	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CTC_RS08660	COG1157	protein secretion by the type III secretion system
CTC_RS08670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CTC_RS08675	COG1766	The M ring may be actively involved in energy transduction
CTC_RS08680	COG1677	Flagellar hook-basal body complex protein FliE
CTC_RS08685	COG1558	bacterial-type flagellum-dependent cell motility
CTC_RS08695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CTC_RS08705	COG0629	single-stranded DNA binding
CTC_RS08720	COG1131	(ABC) transporter
CTC_RS08740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CTC_RS08755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CTC_RS08775	COG0745	RESPONSE REGULATOR receiver
CTC_RS08820	COG3842	ATPase activity
CTC_RS08830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTC_RS08840	COG0151	Belongs to the GarS family
CTC_RS08845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTC_RS08860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CTC_RS08865	COG2089	acid synthase
CTC_RS08870	COG1086	Polysaccharide biosynthesis protein
CTC_RS08885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CTC_RS08895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CTC_RS08900	COG1516	flagellar protein fliS
CTC_RS08925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CTC_RS08930	COG1256	bacterial-type flagellum assembly
CTC_RS08930	COG4786	Flagellar basal body rod
CTC_RS08945	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CTC_RS08945	COG1776	CheC inhibitor of MCP methylation
CTC_RS08950	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CTC_RS08955	COG0835	chemotaxis
CTC_RS08960	COG2201	protein-glutamate methylesterase activity
CTC_RS08965	COG1776	CheC inhibitor of MCP methylation
CTC_RS08970	COG2198	Histidine kinase
CTC_RS08970	COG0643	Histidine kinase
CTC_RS08975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CTC_RS08990	COG0835	chemotaxis
CTC_RS09025	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTC_RS09040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTC_RS09040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CTC_RS09050	COG0352	thiamine-phosphate diphosphorylase activity
CTC_RS09065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTC_RS09085	COG0351	phosphomethylpyrimidine kinase
CTC_RS09100	COG0693	protein deglycase activity
CTC_RS09115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CTC_RS09120	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CTC_RS09130	COG2376	Dihydroxyacetone kinase
CTC_RS09135	COG0010	Belongs to the arginase family
CTC_RS09140	COG2199	diguanylate cyclase activity
CTC_RS09145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTC_RS09150	COG0187	DNA topoisomerase II activity
CTC_RS09155	COG0398	Pfam SNARE associated Golgi protein
CTC_RS09175	COG2720	vancomycin resistance protein
CTC_RS09185	COG0628	permease
CTC_RS09190	COG0697	spore germination
CTC_RS09265	COG5564	TIM-barrel signal transduction protein
CTC_RS09285	COG0534	Mate efflux family protein
CTC_RS09305	COG2205	protein histidine kinase activity
CTC_RS09310	COG0745	RESPONSE REGULATOR receiver
CTC_RS09315	COG0646	methionine synthase
CTC_RS09315	COG1410	methionine synthase
CTC_RS09325	COG0579	oxidoreductase
CTC_RS09345	COG1132	(ABC) transporter
CTC_RS09365	COG0622	Phosphoesterase
CTC_RS09380	COG5002	protein histidine kinase activity
CTC_RS09390	COG0577	efflux transmembrane transporter activity
CTC_RS09390	COG1136	(ABC) transporter
CTC_RS09395	COG1136	(ABC) transporter
CTC_RS09420	COG1346	cytolysis
CTC_RS09425	COG0076	glutamate decarboxylase activity
CTC_RS09475	COG0789	Transcriptional regulator
CTC_RS09475	COG4978	Transcriptional regulator
CTC_RS09500	COG3976	FMN-binding domain protein
CTC_RS09500	COG1053	succinate dehydrogenase
CTC_RS09530	COG3263	regulation of cellular component size
CTC_RS09540	COG4716	Myosin-crossreactive antigen
CTC_RS09550	COG0840	transmembrane signaling receptor activity
CTC_RS09555	COG1396	sequence-specific DNA binding
CTC_RS09575	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CTC_RS09580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CTC_RS09585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CTC_RS09595	COG1114	Component of the transport system for branched-chain amino acids
CTC_RS09610	COG2247	cell wall binding repeat
CTC_RS09610	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS09625	COG0426	domain, Protein
CTC_RS09630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTC_RS09635	COG0252	asparaginase activity
CTC_RS09650	COG3608	succinylglutamate desuccinylase aspartoacylase
CTC_RS09650	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CTC_RS09655	COG0840	transmembrane signaling receptor activity
CTC_RS09665	COG0402	S-adenosylhomocysteine deaminase activity
CTC_RS09670	COG1402	creatininase
CTC_RS09675	COG0697	spore germination
CTC_RS09680	COG2508	Transcriptional regulator
CTC_RS09695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTC_RS09700	COG0456	acetyltransferase
CTC_RS09715	COG1725	Transcriptional regulator
CTC_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTC_RS09760	COG0662	Cupin 2, conserved barrel domain protein
CTC_RS09765	COG0747	negative chemotaxis
CTC_RS09770	COG0601	transmembrane transport
CTC_RS09775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTC_RS09780	COG1126	abc transporter atp-binding protein
CTC_RS09785	COG1124	(ABC) transporter
CTC_RS09790	COG5002	protein histidine kinase activity
CTC_RS09790	COG0642	Histidine kinase
CTC_RS09795	COG0745	RESPONSE REGULATOR receiver
CTC_RS09815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTC_RS09825	COG0494	nUDIX hydrolase
CTC_RS09855	COG1136	(ABC) transporter
CTC_RS09860	COG5002	protein histidine kinase activity
CTC_RS09860	COG3850	Histidine kinase
CTC_RS09895	COG1011	Hydrolase
CTC_RS09900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CTC_RS09955	COG1475	DNA binding
CTC_RS09960	COG1192	Involved in chromosome partitioning
CTC_RS09995	COG1368	sulfuric ester hydrolase activity
CTC_RS10005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTC_RS10010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTC_RS10030	COG5002	protein histidine kinase activity
CTC_RS10035	COG0745	RESPONSE REGULATOR receiver
CTC_RS10040	COG2217	Heavy metal translocating P-type atpase
CTC_RS10045	COG1164	Oligoendopeptidase f
CTC_RS10065	COG0151	Belongs to the GarS family
CTC_RS10075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTC_RS10085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CTC_RS10090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CTC_RS10130	COG2252	PERMEase
CTC_RS10135	COG1115	amino acid carrier protein
CTC_RS10145	COG1966	Carbon starvation protein
CTC_RS10150	COG3275	phosphorelay sensor kinase activity
CTC_RS10155	COG3279	Response regulator of the LytR AlgR family
CTC_RS10170	COG1760	l-serine dehydratase
CTC_RS10175	COG3706	GGDEF domain
CTC_RS10180	COG1725	Transcriptional regulator
CTC_RS10185	COG1131	(ABC) transporter
CTC_RS10195	COG1131	(ABC) transporter
CTC_RS10210	COG2801	Transposase and inactivated derivatives
CTC_RS10235	COG0737	Belongs to the 5'-nucleotidase family
CTC_RS10235	COG1525	nuclease
CTC_RS10235	COG4085	toxin activity
CTC_RS10245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTC_RS10285	COG4129	membrane
CTC_RS10295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTC_RS10310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTC_RS10315	COG0358	DNA primase activity
CTC_RS10330	COG0574	Belongs to the PEP-utilizing enzyme family
CTC_RS10330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTC_RS10335	COG0517	IMP dehydrogenase activity
CTC_RS10345	COG1381	Involved in DNA repair and RecF pathway recombination
CTC_RS10355	COG0295	cytidine deaminase activity
CTC_RS10370	COG1480	7TM receptor with intracellular HD hydrolase
CTC_RS10395	COG0537	adenosine 5'-monophosphoramidase activity
CTC_RS10400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTC_RS10405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTC_RS10435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTC_RS10485	COG1550	Protein conserved in bacteria
CTC_RS10495	COG0095	Lipoate-protein ligase
CTC_RS10500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTC_RS10520	COG1686	Belongs to the peptidase S11 family
CTC_RS10525	COG0564	pseudouridine synthase activity
CTC_RS10530	COG1316	TRANSCRIPTIONal
CTC_RS10535	COG1713	HD superfamily hydrolase involved in NAD metabolism
CTC_RS10545	COG1534	Rna-binding protein
CTC_RS10575	COG1530	ribonuclease E activity
CTC_RS10590	COG1994	Peptidase M50
CTC_RS10595	COG0739	heme binding
CTC_RS10600	COG0772	Belongs to the SEDS family
CTC_RS10605	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CTC_RS10610	COG2894	cell division
CTC_RS10620	COG0768	penicillin binding
CTC_RS10635	COG1077	Cell shape determining protein MreB Mrl
CTC_RS10670	COG1960	acyl-CoA dehydrogenase activity
CTC_RS10675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CTC_RS10680	COG2086	electron transfer activity
CTC_RS10685	COG1960	acyl-CoA dehydrogenase activity
CTC_RS10700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTC_RS10705	COG1114	Component of the transport system for branched-chain amino acids
CTC_RS10715	COG0514	ATP-dependent DNA helicase (RecQ)
CTC_RS10720	COG1268	BioY protein
CTC_RS10725	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS10750	COG0697	spore germination
CTC_RS10760	COG1136	(ABC) transporter
CTC_RS10760	COG0577	efflux transmembrane transporter activity
CTC_RS10785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTC_RS10785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTC_RS10820	COG3620	sequence-specific DNA binding
CTC_RS10885	COG3299	homolog of phage Mu protein gp47
CTC_RS10965	COG0740	serine-type endopeptidase activity
CTC_RS10995	COG1598	PFAM Uncharacterised protein family UPF0150
CTC_RS11055	COG3723	Recombinational DNA repair protein, rece pathway
CTC_RS11060	COG5377	YqaJ viral recombinase family
CTC_RS11095	COG3620	sequence-specific DNA binding
CTC_RS11105	COG0328	RNA-DNA hybrid ribonuclease activity
CTC_RS11110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CTC_RS11115	COG5002	protein histidine kinase activity
CTC_RS11130	COG1472	Belongs to the glycosyl hydrolase 3 family
CTC_RS11140	COG0456	acetyltransferase
CTC_RS11145	COG0475	glutathione-regulated potassium exporter activity
CTC_RS11145	COG0589	response to stress
CTC_RS11195	COG4869	propanediol catabolic process
CTC_RS11210	COG1454	alcohol dehydrogenase
CTC_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
CTC_RS11230	COG4303	Ethanolamine ammonia lyase large subunit
CTC_RS11265	COG2267	carboxylic ester hydrolase activity
CTC_RS11275	COG0346	lactoylglutathione lyase activity
CTC_RS11280	COG1280	lysine exporter protein (LysE YggA)
CTC_RS11310	COG1114	Component of the transport system for branched-chain amino acids
CTC_RS11320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTC_RS11325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTC_RS11335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTC_RS11350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTC_RS11355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTC_RS11375	COG1862	Preprotein translocase
CTC_RS11410	COG1739	Uncharacterized protein family UPF0029
CTC_RS11435	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CTC_RS11445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTC_RS11450	COG2310	stress, protein
CTC_RS11465	COG3853	Toxic anion resistance protein (TelA)
CTC_RS11470	COG2310	stress, protein
CTC_RS11475	COG2310	stress, protein
CTC_RS11510	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CTC_RS11530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTC_RS11575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTC_RS11585	COG0728	peptidoglycan biosynthetic process
CTC_RS11600	COG1215	transferase activity, transferring glycosyl groups
CTC_RS11615	COG0728	peptidoglycan biosynthetic process
CTC_RS11640	COG0438	transferase activity, transferring glycosyl groups
CTC_RS11650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTC_RS11660	COG1982	Orn Lys Arg decarboxylase major
CTC_RS11665	COG1683	Conserved Protein
CTC_RS11675	COG0826	peptidase U32
CTC_RS11680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CTC_RS11695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTC_RS11700	COG0569	domain protein
CTC_RS11705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTC_RS11775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTC_RS11800	COG0726	polysaccharide deacetylase
CTC_RS11845	COG0786	glutamate:sodium symporter activity
CTC_RS11860	COG2056	Na+-H+ antiporter family
CTC_RS11865	COG2056	Na+-H+ antiporter family
CTC_RS11875	COG2966	Psort location CytoplasmicMembrane, score
CTC_RS11885	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CTC_RS11890	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTC_RS11915	COG2204	response regulator
CTC_RS11920	COG3852	Histidine kinase
CTC_RS11925	COG0786	glutamate:sodium symporter activity
CTC_RS11935	COG1394	ATPase activity, coupled to movement of substances
CTC_RS11965	COG1269	ATP hydrolysis coupled proton transport
CTC_RS12000	COG0612	Peptidase, M16
CTC_RS12010	COG2113	Glycine betaine
CTC_RS12015	COG4176	ABC-type proline glycine betaine transport system permease component
CTC_RS12020	COG4175	Glycine betaine
CTC_RS12020	COG0517	IMP dehydrogenase activity
CTC_RS12030	COG1404	Belongs to the peptidase S8 family
CTC_RS12035	COG1609	Transcriptional regulator
CTC_RS12040	COG1879	ABC-type sugar transport system periplasmic component
CTC_RS12045	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTC_RS12065	COG2340	Cysteine-rich secretory protein family
CTC_RS12075	COG0460	homoserine dehydrogenase
CTC_RS12080	COG0527	aspartate kinase activity
CTC_RS12090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTC_RS12105	COG3443	Belongs to the bacterial solute-binding protein 9 family
CTC_RS12105	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTC_RS12110	COG1121	(ABC) transporter
CTC_RS12115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTC_RS12120	COG0735	belongs to the Fur family
CTC_RS12140	COG1266	CAAX protease self-immunity
CTC_RS12150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CTC_RS12155	COG1067	ATP-dependent peptidase activity
CTC_RS12155	COG0470	DNA polymerase III
CTC_RS12185	COG0167	dihydroorotate dehydrogenase activity
CTC_RS12190	COG0543	2 iron, 2 sulfur cluster binding
CTC_RS12320	COG0210	DNA helicase
CTC_RS12325	COG1473	amidohydrolase
CTC_RS12330	COG1473	amidohydrolase
CTC_RS12335	COG4496	protein, YerC YecD
CTC_RS12340	COG1187	pseudouridine synthase activity
CTC_RS12345	COG0741	lytic transglycosylase activity
CTC_RS12365	COG0534	Mate efflux family protein
CTC_RS12395	COG0516	GMP reductase activity
CTC_RS12395	COG0517	IMP dehydrogenase activity
CTC_RS12400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CTC_RS12410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CTC_RS12435	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTC_RS12435	COG0493	'glutamate synthase
CTC_RS12450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTC_RS12455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CTC_RS12460	COG2086	electron transfer activity
CTC_RS12465	COG1960	acyl-CoA dehydrogenase activity
CTC_RS12470	COG1024	Enoyl-CoA hydratase
CTC_RS12480	COG0488	(ABC) transporter
CTC_RS12485	COG0697	spore germination
CTC_RS12490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CTC_RS12515	COG0579	oxidoreductase
CTC_RS12555	COG0802	atpase or kinase
CTC_RS12560	COG1214	PFAM Peptidase M22, glycoprotease
CTC_RS12565	COG0456	acetyltransferase
CTC_RS12585	COG0697	spore germination
CTC_RS12600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTC_RS12605	COG0561	phosphatase activity
CTC_RS12615	COG2033	superoxide reductase activity
CTC_RS12625	COG3459	Glycosyltransferase 36 associated
CTC_RS12630	COG0019	diaminopimelate decarboxylase activity
CTC_RS12635	COG1362	aminopeptidase activity
CTC_RS12640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CTC_RS12650	COG3973	AAA domain
CTC_RS12655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTC_RS12665	COG0281	malic enzyme
CTC_RS12675	COG1288	antiporter activity
CTC_RS12680	COG3051	citrate lyase alpha subunit
CTC_RS12685	COG2301	Belongs to the HpcH HpaI aldolase family
CTC_RS12690	COG3052	prosthetic group binding
CTC_RS12695	COG1802	Transcriptional regulator
CTC_RS12700	COG0071	Belongs to the small heat shock protein (HSP20) family
CTC_RS12710	COG1309	transcriptional regulator
CTC_RS12715	COG2068	MobA-Related Protein
CTC_RS12765	COG1811	Na channel or pump
CTC_RS12785	COG2116	formate transmembrane transporter activity
CTC_RS12795	COG0469	pyruvate kinase activity
CTC_RS12810	COG4109	DRTGG domain
CTC_RS12820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CTC_RS12850	COG0768	penicillin binding
CTC_RS12880	COG0793	Belongs to the peptidase S41A family
CTC_RS12880	COG3409	Peptidoglycan-binding domain 1 protein
CTC_RS12885	COG2177	Part of the ABC transporter FtsEX involved in
CTC_RS12890	COG2884	Cell division ATP-binding protein ftsE
CTC_RS12895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CTC_RS12905	COG0864	Transcriptional regulator
CTC_RS12920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTC_RS12920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTC_RS12945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTC_RS12950	COG1295	ribonuclease BN
CTC_RS12955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CTC_RS12960	COG1012	belongs to the aldehyde dehydrogenase family
CTC_RS12965	COG0549	Belongs to the carbamate kinase family
CTC_RS12970	COG1013	pyruvate-flavodoxin oxidoreductase activity
CTC_RS12975	COG0674	pyruvate-flavodoxin oxidoreductase activity
CTC_RS12980	COG1144	Oxidoreductase
CTC_RS12985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CTC_RS12995	COG0626	cystathionine gamma-synthase activity
CTC_RS13020	COG1028	Short-chain dehydrogenase reductase Sdr
CTC_RS13035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTC_RS13075	COG0280	phosphate acetyltransferase
CTC_RS13080	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CTC_RS13090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CTC_RS13105	COG0492	ferredoxin-NADP+ reductase activity
CTC_RS13110	COG3118	belongs to the thioredoxin family
CTC_RS13130	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CTC_RS13135	COG3051	citrate lyase alpha subunit
CTC_RS13145	COG3052	prosthetic group binding
CTC_RS13155	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTC_RS13155	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTC_RS13205	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CTC_RS13270	COG0201	protein transport
CTC_RS13280	COG1841	ribosomal large subunit assembly
CTC_RS13285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CTC_RS13325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CTC_RS13375	COG0051	transcription antitermination factor activity, RNA binding
CTC_RS13400	COG1358	cellular component organization or biogenesis
CTC_RS13415	COG0222	ribosome binding
CTC_RS13435	COG0250	Participates in transcription elongation, termination and antitermination
CTC_RS13440	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CTC_RS13445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CTC_RS13470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTC_RS13490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTC_RS13505	COG4956	integral membrane protein (PIN domain superfamily)
CTC_RS13520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CTC_RS13530	COG0542	response to heat
CTC_RS13540	COG3880	PFAM UvrB UvrC protein
CTC_RS13545	COG4463	regulation of RNA biosynthetic process
CTC_RS13550	COG0406	alpha-ribazole phosphatase activity
CTC_RS13560	COG1592	Rubrerythrin
CTC_RS13565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CTC_RS14075	COG1376	ErfK ybiS ycfS ynhG family protein
CTC_RS14110	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTC_RS14110	COG2247	cell wall binding repeat
CTC_RS14120	COG1368	sulfuric ester hydrolase activity
CTC_RS14135	COG4659	FMN binding
CTC_RS14175	COG0671	phosphoesterase, PA-phosphatase related
CTC_RS14180	COG0673	inositol 2-dehydrogenase activity
CTC_RS14200	COG2433	Pfam Transposase IS66
CTC_RS14220	COG0501	Belongs to the peptidase M48B family
CTC_RS14255	COG0384	phenazine biosynthesis protein PhzF
CTC_RS14275	COG1518	maintenance of DNA repeat elements
CTC_RS14290	COG5434	Belongs to the glycosyl hydrolase 28 family
CTC_RS14300	COG1334	flagellar protein FlaG
CTC_RS14310	COG2199	diguanylate cyclase activity
CTC_RS14310	COG2203	Gaf domain
CTC_RS14315	COG0840	transmembrane signaling receptor activity
CTC_RS14320	COG2972	Histidine kinase