locus-tag	class	description
BFX80_RS00015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFX80_RS00020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFX80_RS00025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFX80_RS00030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFX80_RS00035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFX80_RS00040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFX80_RS00045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFX80_RS00050	COG1349	DNA-binding transcription factor activity
BFX80_RS00055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFX80_RS00060	COG1187	pseudouridine synthase activity
BFX80_RS00070	COG1801	Protein of unknown function DUF72
BFX80_RS00075	COG0733	neurotransmitter:sodium symporter activity
BFX80_RS00085	COG1737	Transcriptional regulator
BFX80_RS00090	COG0210	DNA helicase
BFX80_RS00095	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFX80_RS00100	COG1607	acyl-coa hydrolase
BFX80_RS00110	COG0573	inorganic phosphate transmembrane transporter activity
BFX80_RS00115	COG0573	inorganic phosphate transmembrane transporter activity
BFX80_RS00120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFX80_RS00125	COG0704	Plays a role in the regulation of phosphate uptake
BFX80_RS00130	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BFX80_RS00145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BFX80_RS00150	COG3161	chorismate lyase activity
BFX80_RS00175	COG1289	transmembrane transporter activity
BFX80_RS00180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFX80_RS00200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFX80_RS00205	COG1758	RNA polymerase activity
BFX80_RS00210	COG0194	GDP metabolic process
BFX80_RS00220	COG2814	Major facilitator Superfamily
BFX80_RS00230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS00235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS00240	COG1764	response to oxidative stress
BFX80_RS00250	COG1561	YicC-like family, N-terminal region
BFX80_RS00255	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BFX80_RS00260	COG0708	Exodeoxyribonuclease III
BFX80_RS00265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BFX80_RS00275	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BFX80_RS00300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFX80_RS00310	COG1217	gtp-binding protein TYPA
BFX80_RS00340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS00360	COG0023	Translation Initiation Factor
BFX80_RS00370	COG0126	phosphoglycerate kinase activity
BFX80_RS00375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFX80_RS00380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFX80_RS00385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BFX80_RS00390	COG1451	nucleotide metabolic process
BFX80_RS00405	COG1953	Uracil, thiamine, allantoin
BFX80_RS00425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BFX80_RS00440	COG0339	signal peptide processing
BFX80_RS00445	COG0733	neurotransmitter:sodium symporter activity
BFX80_RS00450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BFX80_RS00470	COG2186	Transcriptional regulator
BFX80_RS00475	COG1620	l-lactate permease
BFX80_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BFX80_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BFX80_RS00550	COG0081	regulation of translation
BFX80_RS00555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFX80_RS00560	COG0222	ribosome binding
BFX80_RS00565	COG0085	RNA polymerase activity
BFX80_RS00570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFX80_RS00575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BFX80_RS00580	COG0049	tRNA binding
BFX80_RS00585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFX80_RS00590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFX80_RS00595	COG0051	transcription antitermination factor activity, RNA binding
BFX80_RS00600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFX80_RS00605	COG0088	Forms part of the polypeptide exit tunnel
BFX80_RS00610	COG0089	rRNA binding
BFX80_RS00615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFX80_RS00620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFX80_RS00625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFX80_RS00630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFX80_RS00635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFX80_RS00640	COG0255	Belongs to the universal ribosomal protein uL29 family
BFX80_RS00645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFX80_RS00650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFX80_RS00655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFX80_RS00660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFX80_RS00665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFX80_RS00670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFX80_RS00675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFX80_RS00680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFX80_RS00685	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFX80_RS00690	COG1841	ribosomal large subunit assembly
BFX80_RS00695	COG0200	Binds to the 23S rRNA
BFX80_RS00705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFX80_RS00710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFX80_RS00715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFX80_RS00720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFX80_RS00725	COG0202	RNA polymerase activity
BFX80_RS00730	COG0203	ribosomal protein L17
BFX80_RS00740	COG2814	Major facilitator Superfamily
BFX80_RS00745	COG0629	single-stranded DNA binding
BFX80_RS00770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFX80_RS00785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BFX80_RS00800	COG0300	oxidoreductase activity
BFX80_RS00810	COG0415	Belongs to the DNA photolyase family
BFX80_RS00815	COG0789	Transcriptional regulator
BFX80_RS00820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BFX80_RS00825	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BFX80_RS00830	COG1090	epimerase
BFX80_RS00835	COG0564	pseudouridine synthase activity
BFX80_RS00840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFX80_RS00845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFX80_RS00865	COG0142	geranyltranstransferase activity
BFX80_RS00870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BFX80_RS00875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFX80_RS00880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFX80_RS00885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BFX80_RS00890	COG0268	Binds directly to 16S ribosomal RNA
BFX80_RS00895	COG0728	peptidoglycan biosynthetic process
BFX80_RS00900	COG0196	riboflavin kinase activity
BFX80_RS00905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFX80_RS00910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFX80_RS00915	COG1047	Peptidyl-prolyl cis-trans
BFX80_RS00920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BFX80_RS00930	COG4969	Belongs to the N-Me-Phe pilin family
BFX80_RS00955	COG4969	Belongs to the N-Me-Phe pilin family
BFX80_RS01000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BFX80_RS01000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFX80_RS01025	COG0028	Belongs to the TPP enzyme family
BFX80_RS01030	COG0440	acetolactate synthase activity
BFX80_RS01040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFX80_RS01045	COG1183	phosphatidylcholine synthase activity
BFX80_RS01100	COG3022	response to hydroperoxide
BFX80_RS01105	COG3238	Protein conserved in bacteria
BFX80_RS01110	COG0667	Aldo Keto reductase
BFX80_RS01140	COG0733	neurotransmitter:sodium symporter activity
BFX80_RS01155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFX80_RS01175	COG1115	amino acid carrier protein
BFX80_RS01180	COG0589	response to stress
BFX80_RS01190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFX80_RS01195	COG3118	belongs to the thioredoxin family
BFX80_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS01230	COG0850	regulation of cytokinetic process
BFX80_RS01235	COG2894	cell division
BFX80_RS01240	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BFX80_RS01245	COG2925	Exonuclease
BFX80_RS01250	COG1025	Belongs to the peptidase M16 family
BFX80_RS01275	COG4536	flavin adenine dinucleotide binding
BFX80_RS01280	COG4137	Cytochrome C assembly protein
BFX80_RS01285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFX80_RS01290	COG0228	four-way junction DNA binding
BFX80_RS01295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFX80_RS01300	COG0336	Belongs to the RNA methyltransferase TrmD family
BFX80_RS01305	COG0335	large ribosomal subunit rRNA binding
BFX80_RS01310	COG4974	Belongs to the 'phage' integrase family
BFX80_RS01315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFX80_RS01330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BFX80_RS01350	COG2217	Heavy metal translocating P-type atpase
BFX80_RS01355	COG0789	Transcriptional regulator
BFX80_RS01370	COG4172	Belongs to the ABC transporter superfamily
BFX80_RS01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFX80_RS01380	COG0601	transmembrane transport
BFX80_RS01385	COG4166	transmembrane transport
BFX80_RS01390	COG4166	transmembrane transport
BFX80_RS01400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFX80_RS01410	COG0271	Belongs to the BolA IbaG family
BFX80_RS01420	COG0454	-acetyltransferase
BFX80_RS01420	COG0456	acetyltransferase
BFX80_RS01430	COG0742	ribosomal rna small subunit methyltransferase
BFX80_RS01435	COG0552	protein localization to endoplasmic reticulum
BFX80_RS01440	COG2884	Cell division ATP-binding protein ftsE
BFX80_RS01445	COG2177	Part of the ABC transporter FtsEX involved in
BFX80_RS01460	COG1309	transcriptional regulator
BFX80_RS01465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFX80_RS01475	COG0756	dUTP diphosphatase activity
BFX80_RS01480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFX80_RS01485	COG2003	Belongs to the UPF0758 family
BFX80_RS01490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BFX80_RS01495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFX80_RS01505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFX80_RS01520	COG0686	Belongs to the AlaDH PNT family
BFX80_RS01525	COG0180	Tryptophanyl-tRNA synthetase
BFX80_RS01530	COG2391	methyltransferase activity
BFX80_RS01555	COG0450	alkyl hydroperoxide reductase
BFX80_RS01560	COG0492	ferredoxin-NADP+ reductase activity
BFX80_RS01580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFX80_RS01585	COG2171	N-acyltransferase activity
BFX80_RS01590	COG1393	Belongs to the ArsC family
BFX80_RS01595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFX80_RS01610	COG0052	Belongs to the universal ribosomal protein uS2 family
BFX80_RS01615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFX80_RS01620	COG0528	UMP kinase activity
BFX80_RS01625	COG0233	cytoplasmic translational termination
BFX80_RS01630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFX80_RS01640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BFX80_RS01650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFX80_RS01660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFX80_RS01665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFX80_RS01670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFX80_RS01675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFX80_RS01680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFX80_RS01690	COG0825	malonyl-CoA metabolic process
BFX80_RS01695	COG0037	tRNA processing
BFX80_RS01715	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BFX80_RS01725	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS01760	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BFX80_RS01770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFX80_RS01775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFX80_RS01780	COG0140	phosphoribosyl-ATP diphosphatase activity
BFX80_RS01785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFX80_RS01795	COG2226	methyltransferase
BFX80_RS01805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BFX80_RS01810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BFX80_RS01820	COG0018	arginyl-trna synthetase
BFX80_RS01825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFX80_RS01830	COG0254	rRNA binding
BFX80_RS01835	COG0281	malic enzyme
BFX80_RS01875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFX80_RS01880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFX80_RS01885	COG0070	glutamate synthase
BFX80_RS01885	COG0069	glutamate synthase activity
BFX80_RS01885	COG0067	glutamate synthase
BFX80_RS01890	COG0493	'glutamate synthase
BFX80_RS01895	COG0504	CTP synthase activity
BFX80_RS01900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BFX80_RS01905	COG0148	phosphopyruvate hydratase activity
BFX80_RS01915	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BFX80_RS01920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFX80_RS01925	COG1546	Belongs to the CinA family
BFX80_RS01930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFX80_RS01935	COG2137	regulation of response to DNA damage stimulus
BFX80_RS01940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFX80_RS01945	COG0527	aspartate kinase activity
BFX80_RS01950	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BFX80_RS01980	COG5016	pyruvate
BFX80_RS01980	COG0511	ligase activity, forming carbon-carbon bonds
BFX80_RS01985	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BFX80_RS01995	COG2818	Glycosylase
BFX80_RS02010	COG0625	glutathione transferase activity
BFX80_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFX80_RS02025	COG2169	Transcriptional regulator
BFX80_RS02025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFX80_RS02030	COG1607	acyl-coa hydrolase
BFX80_RS02035	COG2031	fatty acid transporter
BFX80_RS02040	COG0534	Mate efflux family protein
BFX80_RS02050	COG3706	GGDEF domain
BFX80_RS02055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFX80_RS02060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFX80_RS02070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFX80_RS02095	COG0604	alcohol dehydrogenase
BFX80_RS02100	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFX80_RS02105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BFX80_RS02120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFX80_RS02125	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BFX80_RS02130	COG1765	OsmC-like protein
BFX80_RS02135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BFX80_RS02140	COG3178	'Phosphotransferase
BFX80_RS02145	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BFX80_RS02150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFX80_RS02160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BFX80_RS02165	COG2967	ApaG domain
BFX80_RS02170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFX80_RS02175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFX80_RS02180	COG0617	tRNA 3'-terminal CCA addition
BFX80_RS02185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BFX80_RS02190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BFX80_RS02195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BFX80_RS02200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFX80_RS02205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BFX80_RS02210	COG0358	DNA primase activity
BFX80_RS02230	COG0583	DNA-binding transcription factor activity
BFX80_RS02235	COG1760	l-serine dehydratase
BFX80_RS02265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFX80_RS02265	COG2146	nitrite reductase [NAD(P)H] activity
BFX80_RS02270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFX80_RS02270	COG2146	nitrite reductase [NAD(P)H] activity
BFX80_RS02275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFX80_RS02280	COG0243	molybdopterin cofactor binding
BFX80_RS02285	COG1648	precorrin-2 dehydrogenase activity
BFX80_RS02285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFX80_RS02320	COG1946	Acyl-CoA thioesterase
BFX80_RS02335	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFX80_RS02345	COG0069	glutamate synthase activity
BFX80_RS02355	COG1061	Type III restriction enzyme res subunit
BFX80_RS02360	COG0180	Tryptophanyl-tRNA synthetase
BFX80_RS02365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BFX80_RS02370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFX80_RS02395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BFX80_RS02405	COG0425	Belongs to the sulfur carrier protein TusA family
BFX80_RS02415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFX80_RS02420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFX80_RS02430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BFX80_RS02435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BFX80_RS02450	COG0235	Class ii aldolase
BFX80_RS02455	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BFX80_RS02470	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS02500	COG0861	Integral membrane protein TerC family
BFX80_RS02505	COG0563	adenylate kinase activity
BFX80_RS02510	COG1214	PFAM Peptidase M22, glycoprotease
BFX80_RS02515	COG1968	undecaprenyl-diphosphatase activity
BFX80_RS02520	COG0742	ribosomal rna small subunit methyltransferase
BFX80_RS02525	COG2937	Belongs to the GPAT DAPAT family
BFX80_RS02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFX80_RS02540	COG3091	SprT-like family
BFX80_RS02545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFX80_RS02550	COG0697	spore germination
BFX80_RS02560	COG0784	Response regulator, receiver
BFX80_RS02560	COG2198	Histidine kinase
BFX80_RS02560	COG2205	protein histidine kinase activity
BFX80_RS02570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFX80_RS02580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFX80_RS02590	COG0037	tRNA processing
BFX80_RS02595	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BFX80_RS02600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BFX80_RS02605	COG0385	Bile acid
BFX80_RS02610	COG3148	PFAM DTW domain containing protein
BFX80_RS02615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFX80_RS02620	COG0569	domain protein
BFX80_RS02630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFX80_RS02635	COG0242	peptide deformylase activity
BFX80_RS02640	COG1652	LysM domain
BFX80_RS02645	COG0758	DNA mediated transformation
BFX80_RS02655	COG0009	L-threonylcarbamoyladenylate synthase
BFX80_RS02660	COG0408	coproporphyrinogen oxidase activity
BFX80_RS02665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFX80_RS02685	COG1716	ATPase activity
BFX80_RS02685	COG5001	Diguanylate cyclase
BFX80_RS02700	COG1160	GTP binding
BFX80_RS02710	COG2976	Protein conserved in bacteria
BFX80_RS02715	COG0124	histidyl-tRNA synthetase
BFX80_RS02720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BFX80_RS02725	COG1426	Protein conserved in bacteria
BFX80_RS02735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BFX80_RS02740	COG0105	UTP biosynthetic process
BFX80_RS02785	COG1862	Preprotein translocase
BFX80_RS02790	COG0343	queuine tRNA-ribosyltransferase activity
BFX80_RS02795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFX80_RS02820	COG1960	acyl-CoA dehydrogenase activity
BFX80_RS02830	COG0714	Associated with various cellular activities
BFX80_RS02995	COG2274	protein secretion by the type I secretion system
BFX80_RS03005	COG1538	Outer membrane efflux protein
BFX80_RS03025	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFX80_RS03050	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS03055	COG3724	N-succinylarginine dihydrolase activity
BFX80_RS03105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFX80_RS03110	COG4160	amino acid transport
BFX80_RS03120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFX80_RS03130	COG2988	succinylglutamate desuccinylase activity
BFX80_RS03140	COG3040	lipid binding
BFX80_RS03155	COG0583	DNA-binding transcription factor activity
BFX80_RS03165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFX80_RS03165	COG3153	acetyltransferase
BFX80_RS03175	COG0625	glutathione transferase activity
BFX80_RS03180	COG0583	DNA-binding transcription factor activity
BFX80_RS03185	COG0725	ABC transporter, periplasmic molybdate-binding protein
BFX80_RS03190	COG4149	molybdate abc transporter
BFX80_RS03200	COG0633	Ferredoxin
BFX80_RS03200	COG3217	Mosc domain protein beta barrel domain protein
BFX80_RS03205	COG0123	including yeast histone deacetylase and acetoin utilization protein
BFX80_RS03225	COG1609	Transcriptional regulator
BFX80_RS03235	COG1105	Belongs to the carbohydrate kinase PfkB family
BFX80_RS03240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFX80_RS03240	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BFX80_RS03240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFX80_RS03245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS03260	COG0745	RESPONSE REGULATOR receiver
BFX80_RS03265	COG2205	protein histidine kinase activity
BFX80_RS03275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFX80_RS03280	COG2610	gluconate transmembrane transporter activity
BFX80_RS03285	COG3265	gluconokinase activity
BFX80_RS03290	COG1609	Transcriptional regulator
BFX80_RS03295	COG2431	L-lysine efflux transmembrane transporter activity
BFX80_RS03305	COG0693	protein deglycase activity
BFX80_RS03310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BFX80_RS03315	COG1522	sequence-specific DNA binding
BFX80_RS03325	COG0006	proline dipeptidase activity
BFX80_RS03335	COG1522	sequence-specific DNA binding
BFX80_RS03340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFX80_RS03345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFX80_RS03350	COG2902	Dehydrogenase
BFX80_RS03360	COG0167	dihydroorotate dehydrogenase activity
BFX80_RS03365	COG3130	regulation of translation
BFX80_RS03370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFX80_RS03370	COG0116	Belongs to the methyltransferase superfamily
BFX80_RS03385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFX80_RS03390	COG1757	Na H antiporter
BFX80_RS03395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFX80_RS03400	COG0501	Belongs to the peptidase M48B family
BFX80_RS03405	COG0436	Aminotransferase
BFX80_RS03410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFX80_RS03415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFX80_RS03460	COG1131	(ABC) transporter
BFX80_RS03465	COG0842	Transport permease protein
BFX80_RS03470	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFX80_RS03470	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFX80_RS03475	COG0778	Nitroreductase
BFX80_RS03505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFX80_RS03510	COG0488	(ABC) transporter
BFX80_RS03520	COG2081	HI0933 family
BFX80_RS03525	COG0583	DNA-binding transcription factor activity
BFX80_RS03545	COG4575	ribosome binding
BFX80_RS03555	COG3264	Mechanosensitive ion channel
BFX80_RS03555	COG1196	nuclear chromosome segregation
BFX80_RS03585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFX80_RS03590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFX80_RS03595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFX80_RS03605	COG3100	YcgL domain-containing protein
BFX80_RS03610	COG2983	Belongs to the UPF0260 family
BFX80_RS03615	COG1309	transcriptional regulator
BFX80_RS03620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFX80_RS03635	COG0791	NLP P60 protein
BFX80_RS03640	COG0583	DNA-binding transcription factor activity
BFX80_RS03645	COG2814	Major facilitator Superfamily
BFX80_RS03650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFX80_RS03660	COG4134	Bacterial extracellular solute-binding protein
BFX80_RS03665	COG4135	transport system, permease component
BFX80_RS03670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFX80_RS03695	COG3133	Outer membrane lipoprotein
BFX80_RS03700	COG2224	Isocitrate lyase
BFX80_RS03715	COG2850	peptidyl-arginine hydroxylation
BFX80_RS03725	COG2915	High frequency lysogenization protein hflD homolog
BFX80_RS03730	COG0482	sulfurtransferase activity
BFX80_RS03750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BFX80_RS03755	COG0542	response to heat
BFX80_RS03760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFX80_RS03765	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BFX80_RS03770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BFX80_RS03775	COG1674	ftsk spoiiie
BFX80_RS03780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BFX80_RS03785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFX80_RS03795	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS03800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFX80_RS03805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFX80_RS03810	COG2423	ornithine cyclodeaminase activity
BFX80_RS03825	COG0659	secondary active sulfate transmembrane transporter activity
BFX80_RS03830	COG0589	response to stress
BFX80_RS03850	COG0393	Putative heavy-metal-binding
BFX80_RS03855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFX80_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS03870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFX80_RS03900	COG2986	histidine ammonia-lyase
BFX80_RS03920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFX80_RS03925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFX80_RS03940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFX80_RS03950	COG2974	May be involved in recombination
BFX80_RS03960	COG0824	Thioesterase
BFX80_RS03980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BFX80_RS03985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFX80_RS04005	COG0459	protein refolding
BFX80_RS04010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFX80_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS04030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFX80_RS04035	COG2183	response to ionizing radiation
BFX80_RS04040	COG2918	glutathione biosynthetic process
BFX80_RS04045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BFX80_RS04055	COG0579	oxidoreductase
BFX80_RS04065	COG0494	nUDIX hydrolase
BFX80_RS04080	COG0745	RESPONSE REGULATOR receiver
BFX80_RS04085	COG0730	response to heat
BFX80_RS04090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFX80_RS04095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFX80_RS04105	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BFX80_RS04110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS04115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS04120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS04135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFX80_RS04140	COG0166	Belongs to the GPI family
BFX80_RS04145	COG0676	glucose-6-phosphate 1-epimerase activity
BFX80_RS04150	COG0837	glucose binding
BFX80_RS04170	COG3447	MASE1 domain protein
BFX80_RS04170	COG5001	Diguanylate cyclase
BFX80_RS04170	COG5002	protein histidine kinase activity
BFX80_RS04180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BFX80_RS04210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFX80_RS04220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BFX80_RS04270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFX80_RS04275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BFX80_RS04280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BFX80_RS04285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BFX80_RS04290	COG0585	pseudouridine synthase activity
BFX80_RS04295	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BFX80_RS04300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BFX80_RS04320	COG1538	Outer membrane efflux protein
BFX80_RS04325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFX80_RS04330	COG1560	Kdo2-lipid A biosynthetic process
BFX80_RS04350	COG0488	(ABC) transporter
BFX80_RS04360	COG1366	Belongs to the anti-sigma-factor antagonist family
BFX80_RS04385	COG2326	polyphosphate kinase activity
BFX80_RS04395	COG4181	ATPase activity
BFX80_RS04400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BFX80_RS04405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFX80_RS04420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFX80_RS04430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS04440	COG1215	transferase activity, transferring glycosyl groups
BFX80_RS04450	COG2261	transglycosylase associated protein
BFX80_RS04455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFX80_RS04460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFX80_RS04460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFX80_RS04470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BFX80_RS04475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFX80_RS04485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BFX80_RS04495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BFX80_RS04505	COG0129	dihydroxy-acid dehydratase activity
BFX80_RS04515	COG0433	COG0433 Predicted ATPase
BFX80_RS04525	COG0494	nUDIX hydrolase
BFX80_RS04530	COG1011	Hydrolase
BFX80_RS04535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BFX80_RS04540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFX80_RS04545	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BFX80_RS04555	COG0442	prolyl-tRNA aminoacylation
BFX80_RS04570	COG2116	formate transmembrane transporter activity
BFX80_RS04575	COG2116	formate transmembrane transporter activity
BFX80_RS04600	COG0322	excinuclease ABC activity
BFX80_RS04620	COG3842	ATPase activity
BFX80_RS04625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFX80_RS04630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BFX80_RS04635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFX80_RS04640	COG0137	argininosuccinate synthase activity
BFX80_RS04665	COG0697	spore germination
BFX80_RS04670	COG1414	Transcriptional regulator
BFX80_RS04715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFX80_RS04725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS04730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS04730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS04735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS04735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS04745	COG1414	Transcriptional regulator
BFX80_RS04770	COG2855	membrane
BFX80_RS04790	COG2824	Alkylphosphonate utilization operon protein PhnA
BFX80_RS04800	COG4770	biotin carboxylase activity
BFX80_RS04810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFX80_RS04815	COG1960	acyl-CoA dehydrogenase activity
BFX80_RS04820	COG1125	glycine betaine transport
BFX80_RS04820	COG0517	IMP dehydrogenase activity
BFX80_RS04825	COG1174	glycine betaine transport
BFX80_RS04830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BFX80_RS04835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFX80_RS04865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BFX80_RS04870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BFX80_RS04875	COG1984	allophanate hydrolase subunit 2
BFX80_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
BFX80_RS04900	COG1960	acyl-CoA dehydrogenase activity
BFX80_RS04905	COG1024	Enoyl-CoA hydratase
BFX80_RS04910	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFX80_RS04910	COG1024	Enoyl-CoA hydratase
BFX80_RS04925	COG0534	Mate efflux family protein
BFX80_RS04930	COG3123	guanosine phosphorylase activity
BFX80_RS04935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BFX80_RS04945	COG1301	dicarboxylic acid transport
BFX80_RS04950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFX80_RS04980	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFX80_RS04985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFX80_RS04990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFX80_RS04995	COG0215	cysteine-tRNA ligase activity
BFX80_RS05000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFX80_RS05005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFX80_RS05030	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFX80_RS05035	COG0740	serine-type endopeptidase activity
BFX80_RS05040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFX80_RS05045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BFX80_RS05060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFX80_RS05065	COG0583	DNA-binding transcription factor activity
BFX80_RS05070	COG2130	NADP-dependent
BFX80_RS05075	COG1979	alcohol dehydrogenase
BFX80_RS05080	COG0523	cobalamin synthesis protein
BFX80_RS05095	COG0602	queuosine metabolic process
BFX80_RS05100	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFX80_RS05105	COG4251	negative regulation of phosphorylation
BFX80_RS05105	COG5001	Diguanylate cyclase
BFX80_RS05105	COG3706	GGDEF domain
BFX80_RS05105	COG2203	Gaf domain
BFX80_RS05110	COG0583	DNA-binding transcription factor activity
BFX80_RS05115	COG0534	Mate efflux family protein
BFX80_RS05120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS05130	COG0583	DNA-binding transcription factor activity
BFX80_RS05140	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFX80_RS05155	COG1846	Transcriptional regulator
BFX80_RS05160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BFX80_RS05170	COG1063	alcohol dehydrogenase
BFX80_RS05175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFX80_RS05180	COG0697	spore germination
BFX80_RS05185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFX80_RS05190	COG0583	DNA-binding transcription factor activity
BFX80_RS05210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFX80_RS05215	COG0786	glutamate:sodium symporter activity
BFX80_RS05225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFX80_RS05235	COG2194	sulfuric ester hydrolase activity
BFX80_RS05245	COG0297	glycogen (starch) synthase activity
BFX80_RS05255	COG1473	amidohydrolase
BFX80_RS05260	COG2885	chlorophyll binding
BFX80_RS05265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFX80_RS05275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFX80_RS05280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BFX80_RS05285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BFX80_RS05290	COG0072	phenylalanine-tRNA ligase activity
BFX80_RS05295	COG0776	regulation of translation
BFX80_RS05300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFX80_RS05305	COG0569	domain protein
BFX80_RS05310	COG0733	neurotransmitter:sodium symporter activity
BFX80_RS05315	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BFX80_RS05325	COG0776	regulation of translation
BFX80_RS05330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BFX80_RS05340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BFX80_RS05345	COG1289	transmembrane transporter activity
BFX80_RS05365	COG1349	DNA-binding transcription factor activity
BFX80_RS05370	COG2271	Major facilitator Superfamily
BFX80_RS05375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BFX80_RS05380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFX80_RS05385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFX80_RS05410	COG1956	GAF domain-containing protein
BFX80_RS05415	COG1464	Belongs to the NlpA lipoprotein family
BFX80_RS05420	COG2011	ABC-type metal ion transport system permease component
BFX80_RS05425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFX80_RS05430	COG0307	riboflavin synthase, alpha
BFX80_RS05435	COG2252	PERMEase
BFX80_RS05440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFX80_RS05445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BFX80_RS05450	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFX80_RS05460	COG1442	glycosyl transferase family 8
BFX80_RS05475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFX80_RS05485	COG1396	sequence-specific DNA binding
BFX80_RS05485	COG1917	Cupin 2, conserved barrel domain protein
BFX80_RS05490	COG3852	Histidine kinase
BFX80_RS05495	COG2204	response regulator
BFX80_RS05505	COG4662	Binding-protein-dependent transport system inner membrane component
BFX80_RS05515	COG0746	molybdenum cofactor guanylyltransferase activity
BFX80_RS05520	COG1763	Mo-molybdopterin cofactor biosynthetic process
BFX80_RS05525	COG0303	'Molybdopterin
BFX80_RS05530	COG0315	cyclic pyranopterin monophosphate synthase activity
BFX80_RS05535	COG0314	molybdopterin synthase activity
BFX80_RS05540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BFX80_RS05555	COG0788	formyltetrahydrofolate deformylase activity
BFX80_RS05570	COG0159	tryptophan synthase activity
BFX80_RS05585	COG0582	viral genome integration into host DNA
BFX80_RS05605	COG0629	single-stranded DNA binding
BFX80_RS05645	COG4626	Terminase
BFX80_RS05645	COG1802	Transcriptional regulator
BFX80_RS05715	COG1802	Transcriptional regulator
BFX80_RS05715	COG4626	Terminase
BFX80_RS05805	COG0758	DNA mediated transformation
BFX80_RS05810	COG0438	transferase activity, transferring glycosyl groups
BFX80_RS05820	COG2813	Specifically methylates the guanine in position
BFX80_RS05825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFX80_RS05835	COG0494	nUDIX hydrolase
BFX80_RS05840	COG3151	Protein conserved in bacteria
BFX80_RS05845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BFX80_RS05850	COG0175	sulfate reduction
BFX80_RS05855	COG2895	sulfate adenylyltransferase (ATP) activity
BFX80_RS05865	COG3604	Transcriptional regulator
BFX80_RS05870	COG0500	methyltransferase
BFX80_RS05875	COG4106	trans-aconitate 2-methyltransferase activity
BFX80_RS05880	COG0166	Belongs to the GPI family
BFX80_RS05900	COG3830	Belongs to the UPF0237 family
BFX80_RS05900	COG0560	Phosphoserine phosphatase
BFX80_RS05920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFX80_RS05930	COG0688	phosphatidylethanolamine metabolic process
BFX80_RS05940	COG2252	PERMEase
BFX80_RS05955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFX80_RS05960	COG4660	Part of a membrane complex involved in electron transport
BFX80_RS05965	COG4659	FMN binding
BFX80_RS05970	COG4658	electron transport chain
BFX80_RS05975	COG4656	Part of a membrane complex involved in electron transport
BFX80_RS05980	COG2878	Part of a membrane complex involved in electron transport
BFX80_RS05985	COG4657	Part of a membrane complex involved in electron transport
BFX80_RS05995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFX80_RS05995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFX80_RS06015	COG0489	protein tyrosine kinase activity
BFX80_RS06020	COG0717	Belongs to the dCTP deaminase family
BFX80_RS06025	COG3240	lipase activity
BFX80_RS06025	COG4625	pathogenesis
BFX80_RS06030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFX80_RS06035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BFX80_RS06040	COG0628	permease
BFX80_RS06055	COG0432	Pfam Uncharacterised protein family UPF0047
BFX80_RS06060	COG0583	DNA-binding transcription factor activity
BFX80_RS06080	COG1611	Belongs to the LOG family
BFX80_RS06095	COG0427	acetyl-CoA hydrolase
BFX80_RS06105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFX80_RS06125	COG1596	polysaccharide export
BFX80_RS06135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFX80_RS06160	COG1215	transferase activity, transferring glycosyl groups
BFX80_RS06175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFX80_RS06195	COG0438	transferase activity, transferring glycosyl groups
BFX80_RS06200	COG0438	transferase activity, transferring glycosyl groups
BFX80_RS06205	COG1596	polysaccharide export
BFX80_RS06210	COG3206	protein involved in exopolysaccharide biosynthesis
BFX80_RS06210	COG0489	protein tyrosine kinase activity
BFX80_RS06215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFX80_RS06230	COG2244	polysaccharide biosynthetic process
BFX80_RS06265	COG0438	transferase activity, transferring glycosyl groups
BFX80_RS06280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFX80_RS06290	COG4303	Ethanolamine ammonia lyase large subunit
BFX80_RS06295	COG4302	ethanolamine ammonia-lyase activity
BFX80_RS06300	COG0531	amino acid
BFX80_RS06305	COG0352	thiamine-phosphate diphosphorylase activity
BFX80_RS06310	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BFX80_RS06315	COG1555	photosystem II stabilization
BFX80_RS06315	COG3568	Endonuclease Exonuclease Phosphatase
BFX80_RS06370	COG0583	DNA-binding transcription factor activity
BFX80_RS06375	COG3791	Glutathione-dependent formaldehyde-activating
BFX80_RS06390	COG2175	clavaminate synthase activity
BFX80_RS06395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFX80_RS06430	COG1294	oxidase, subunit
BFX80_RS06435	COG1271	oxidase subunit
BFX80_RS06440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFX80_RS06470	COG0829	nickel cation binding
BFX80_RS06475	COG0831	urea catabolic process
BFX80_RS06480	COG0832	Belongs to the urease beta subunit family
BFX80_RS06485	COG0804	urea catabolic process
BFX80_RS06490	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BFX80_RS06495	COG0830	nickel cation binding
BFX80_RS06500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BFX80_RS06520	COG0697	spore germination
BFX80_RS06530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFX80_RS06535	COG1121	(ABC) transporter
BFX80_RS06550	COG1469	GTP cyclohydrolase I activity
BFX80_RS06555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS06565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS06565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS06600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFX80_RS06625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS06630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS06635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS06640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS06650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS06660	COG4948	Mandelate Racemase Muconate Lactonizing
BFX80_RS06670	COG2186	Transcriptional regulator
BFX80_RS06685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS06695	COG2070	2-Nitropropane dioxygenase
BFX80_RS06700	COG0028	Belongs to the TPP enzyme family
BFX80_RS06710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFX80_RS06740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFX80_RS06755	COG1442	glycosyl transferase family 8
BFX80_RS06755	COG1216	Glycosyl transferase, family 2
BFX80_RS06785	COG3307	-O-antigen
BFX80_RS06820	COG0156	8-amino-7-oxononanoate synthase activity
BFX80_RS06825	COG0604	alcohol dehydrogenase
BFX80_RS06825	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS06825	COG3321	synthase
BFX80_RS06850	COG3273	potassium ion transport
BFX80_RS06850	COG0471	metal ion transport
BFX80_RS06850	COG3273	potassium ion transport
BFX80_RS06850	COG0471	metal ion transport
BFX80_RS06860	COG0175	sulfate reduction
BFX80_RS06900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BFX80_RS06910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFX80_RS06910	COG0517	IMP dehydrogenase activity
BFX80_RS06920	COG1088	dTDP-glucose 4,6-dehydratase activity
BFX80_RS06925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFX80_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS06955	COG0583	DNA-binding transcription factor activity
BFX80_RS06975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFX80_RS06980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS06985	COG0753	catalase activity
BFX80_RS07000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFX80_RS07010	COG2375	cellular response to nickel ion
BFX80_RS07040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFX80_RS07045	COG1312	Catalyzes the dehydration of D-mannonate
BFX80_RS07050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS07070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFX80_RS07075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFX80_RS07105	COG2186	Transcriptional regulator
BFX80_RS07110	COG0659	secondary active sulfate transmembrane transporter activity
BFX80_RS07120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS07130	COG0583	DNA-binding transcription factor activity
BFX80_RS07135	COG0583	DNA-binding transcription factor activity
BFX80_RS07140	COG2936	dipeptidyl-peptidase activity
BFX80_RS07145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS07150	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS07160	COG0583	DNA-binding transcription factor activity
BFX80_RS07180	COG1620	l-lactate permease
BFX80_RS07185	COG0697	spore germination
BFX80_RS07200	COG1741	Belongs to the pirin family
BFX80_RS07210	COG0583	DNA-binding transcription factor activity
BFX80_RS07215	COG1063	alcohol dehydrogenase
BFX80_RS07220	COG0156	8-amino-7-oxononanoate synthase activity
BFX80_RS07235	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BFX80_RS07240	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BFX80_RS07240	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BFX80_RS07245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS07295	COG1881	PFAM PEBP family protein
BFX80_RS07315	COG0824	Thioesterase
BFX80_RS07315	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFX80_RS07325	COG3246	L-lysine catabolic process to acetate
BFX80_RS07340	COG1917	Cupin 2, conserved barrel domain protein
BFX80_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS07360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFX80_RS07375	COG1609	Transcriptional regulator
BFX80_RS07380	COG2084	Dehydrogenase
BFX80_RS07385	COG3395	kinase activity
BFX80_RS07390	COG0235	Class ii aldolase
BFX80_RS07395	COG3622	Belongs to the hyi family
BFX80_RS07400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFX80_RS07405	COG2610	gluconate transmembrane transporter activity
BFX80_RS07425	COG3706	GGDEF domain
BFX80_RS07425	COG4251	negative regulation of phosphorylation
BFX80_RS07425	COG2203	Gaf domain
BFX80_RS07425	COG5001	Diguanylate cyclase
BFX80_RS07430	COG3829	transcription factor binding
BFX80_RS07435	COG0659	secondary active sulfate transmembrane transporter activity
BFX80_RS07440	COG1454	alcohol dehydrogenase
BFX80_RS07455	COG0583	DNA-binding transcription factor activity
BFX80_RS07470	COG0583	DNA-binding transcription factor activity
BFX80_RS07480	COG2076	Multidrug Resistance protein
BFX80_RS07485	COG2076	Multidrug Resistance protein
BFX80_RS07500	COG2197	response regulator
BFX80_RS07505	COG3850	Histidine kinase
BFX80_RS07510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFX80_RS07515	COG0004	ammonium transporteR
BFX80_RS07525	COG3036	rescue of stalled ribosome
BFX80_RS07530	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFX80_RS07530	COG1902	pentaerythritol trinitrate reductase activity
BFX80_RS07535	COG0583	DNA-binding transcription factor activity
BFX80_RS07545	COG1253	flavin adenine dinucleotide binding
BFX80_RS07565	COG2828	Protein conserved in bacteria
BFX80_RS07570	COG0583	DNA-binding transcription factor activity
BFX80_RS07595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFX80_RS07615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFX80_RS07635	COG4964	Belongs to the GSP D family
BFX80_RS07690	COG2249	NAD(P)H dehydrogenase (quinone) activity
BFX80_RS07715	COG1944	ATP diphosphatase activity
BFX80_RS07740	COG0439	Biotin carboxylase
BFX80_RS07755	COG1116	anion transmembrane transporter activity
BFX80_RS07775	COG1120	ATPase activity
BFX80_RS07780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFX80_RS07795	COG4773	Receptor
BFX80_RS07800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFX80_RS07815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFX80_RS07820	COG3243	poly(R)-hydroxyalkanoic acid synthase
BFX80_RS07830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFX80_RS07835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFX80_RS07835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFX80_RS07845	COG0356	it plays a direct role in the translocation of protons across the membrane
BFX80_RS07860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFX80_RS07870	COG1271	oxidase subunit
BFX80_RS07875	COG1294	oxidase, subunit
BFX80_RS07885	COG4988	ABC transporter
BFX80_RS07890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFX80_RS07895	COG0656	L-ascorbic acid biosynthetic process
BFX80_RS07910	COG2814	Major facilitator Superfamily
BFX80_RS07920	COG3118	belongs to the thioredoxin family
BFX80_RS07925	COG0640	Transcriptional regulator
BFX80_RS07930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFX80_RS07955	COG3842	ATPase activity
BFX80_RS07975	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BFX80_RS07980	COG2188	Transcriptional regulator
BFX80_RS07995	COG1064	alcohol dehydrogenase
BFX80_RS08005	COG4807	Protein conserved in bacteria
BFX80_RS08020	COG1230	cation diffusion facilitator family transporter
BFX80_RS08025	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS08030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BFX80_RS08160	COG5002	protein histidine kinase activity
BFX80_RS08160	COG5001	Diguanylate cyclase
BFX80_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS08200	COG1024	Enoyl-CoA hydratase
BFX80_RS08205	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BFX80_RS08210	COG5000	phosphorelay sensor kinase activity
BFX80_RS08215	COG0415	Belongs to the DNA photolyase family
BFX80_RS08230	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BFX80_RS08250	COG0789	Transcriptional regulator
BFX80_RS08255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BFX80_RS08260	COG1970	mechanosensitive ion channel activity
BFX80_RS08265	COG0084	hydrolase, TatD family'
BFX80_RS08270	COG5001	Diguanylate cyclase
BFX80_RS08270	COG3300	MHYT domain
BFX80_RS08290	COG0556	nucleotide-excision repair
BFX80_RS08325	COG3023	N-Acetylmuramoyl-L-alanine amidase
BFX80_RS08335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFX80_RS08400	COG0583	DNA-binding transcription factor activity
BFX80_RS08410	COG1473	amidohydrolase
BFX80_RS08420	COG2942	2-epimerase
BFX80_RS08450	COG1609	Transcriptional regulator
BFX80_RS08455	COG2814	Major facilitator Superfamily
BFX80_RS08465	COG1252	NADH dehydrogenase
BFX80_RS08475	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS08485	COG3314	Sporulation integral membrane protein YlbJ
BFX80_RS08530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS08540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS08555	COG0583	DNA-binding transcription factor activity
BFX80_RS08560	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS08580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS08580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS08590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS08595	COG2873	o-acetylhomoserine
BFX80_RS08625	COG0318	PFAM AMP-dependent synthetase and ligase
BFX80_RS08655	COG1957	nucleoside hydrolase
BFX80_RS08665	COG2040	homocysteine
BFX80_RS08670	COG0833	amino acid
BFX80_RS08675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFX80_RS08680	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS08685	COG0531	amino acid
BFX80_RS08690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFX80_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS08725	COG0243	molybdopterin cofactor binding
BFX80_RS08730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BFX80_RS08735	COG3549	Plasmid maintenance system killer
BFX80_RS08740	COG3093	addiction module antidote protein HigA
BFX80_RS08750	COG0697	spore germination
BFX80_RS08755	COG2207	Transcriptional regulator
BFX80_RS08755	COG0662	Cupin 2, conserved barrel domain protein
BFX80_RS08775	COG2010	Cytochrome c
BFX80_RS08795	COG2814	Major facilitator Superfamily
BFX80_RS08800	COG1609	Transcriptional regulator
BFX80_RS08805	COG1879	ABC-type sugar transport system periplasmic component
BFX80_RS08810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFX80_RS08815	COG1129	ABC transporter
BFX80_RS08825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BFX80_RS08855	COG1360	Flagellar Motor Protein
BFX80_RS08860	COG2198	Histidine kinase
BFX80_RS08860	COG0643	Histidine kinase
BFX80_RS08870	COG0840	transmembrane signaling receptor activity
BFX80_RS08875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BFX80_RS08885	COG0745	RESPONSE REGULATOR receiver
BFX80_RS08900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BFX80_RS08925	COG1815	bacterial-type flagellum-dependent cell motility
BFX80_RS08935	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BFX80_RS08940	COG1749	Flagellar hook protein flgE
BFX80_RS08945	COG4787	bacterial-type flagellum-dependent cell motility
BFX80_RS08960	COG1706	bacterial-type flagellum-dependent cell motility
BFX80_RS08970	COG1705	Flagellar rod assembly protein muramidase FlgJ
BFX80_RS08970	COG3951	Flagellar rod assembly protein muramidase FlgJ
BFX80_RS08975	COG1256	bacterial-type flagellum assembly
BFX80_RS08980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BFX80_RS08990	COG1987	bacterial-type flagellum assembly
BFX80_RS09060	COG1191	sigma factor activity
BFX80_RS09070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS09090	COG1566	PFAM secretion protein HlyD family protein
BFX80_RS09095	COG1289	transmembrane transporter activity
BFX80_RS09105	COG2610	gluconate transmembrane transporter activity
BFX80_RS09120	COG3386	PFAM SMP-30 Gluconolaconase
BFX80_RS09125	COG0800	Aldolase
BFX80_RS09130	COG3734	2-keto-3-deoxy-galactonokinase
BFX80_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS09140	COG4948	Mandelate Racemase Muconate Lactonizing
BFX80_RS09175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFX80_RS09180	COG5001	Diguanylate cyclase
BFX80_RS09180	COG3300	MHYT domain
BFX80_RS09195	COG0534	Mate efflux family protein
BFX80_RS09205	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BFX80_RS09205	COG0316	Belongs to the HesB IscA family
BFX80_RS09215	COG0456	acetyltransferase
BFX80_RS09220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFX80_RS09225	COG1917	Cupin 2, conserved barrel domain protein
BFX80_RS09230	COG5001	Diguanylate cyclase
BFX80_RS09230	COG1716	ATPase activity
BFX80_RS09260	COG0735	belongs to the Fur family
BFX80_RS09275	COG1121	(ABC) transporter
BFX80_RS09280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFX80_RS09285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFX80_RS09290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BFX80_RS09295	COG5642	Protein of unknown function (DUF2384)
BFX80_RS09305	COG2166	iron-sulfur cluster assembly
BFX80_RS09320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BFX80_RS09340	COG0288	reversible hydration of carbon dioxide
BFX80_RS09345	COG0747	negative chemotaxis
BFX80_RS09350	COG0601	transmembrane transport
BFX80_RS09355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFX80_RS09360	COG0444	Belongs to the ABC transporter superfamily
BFX80_RS09365	COG4608	Belongs to the ABC transporter superfamily
BFX80_RS09370	COG0583	DNA-binding transcription factor activity
BFX80_RS09375	COG0006	proline dipeptidase activity
BFX80_RS09380	COG0429	hydrolase of the alpha beta-hydrolase fold
BFX80_RS09390	COG2814	Major facilitator Superfamily
BFX80_RS09400	COG3012	SEC-C Motif Domain Protein
BFX80_RS09405	COG2911	Protein conserved in bacteria
BFX80_RS09425	COG0604	alcohol dehydrogenase
BFX80_RS09435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFX80_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS09465	COG2885	chlorophyll binding
BFX80_RS09470	COG0823	Involved in the tonB-independent uptake of proteins
BFX80_RS09490	COG0824	Thioesterase
BFX80_RS09495	COG2255	four-way junction helicase activity
BFX80_RS09500	COG0632	four-way junction helicase activity
BFX80_RS09505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BFX80_RS09510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BFX80_RS09520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFX80_RS09535	COG1957	nucleoside hydrolase
BFX80_RS09540	COG1056	cytidyltransferase-related domain
BFX80_RS09540	COG1051	belongs to the nudix hydrolase family
BFX80_RS09545	COG0583	DNA-binding transcription factor activity
BFX80_RS09550	COG1027	Aspartate ammonia-lyase
BFX80_RS09565	COG0022	dehydrogenase e1 component
BFX80_RS09580	COG1301	dicarboxylic acid transport
BFX80_RS09590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS09595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS09605	COG2840	Smr protein MutS2
BFX80_RS09615	COG1177	transmembrane transport
BFX80_RS09620	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFX80_RS09625	COG3842	ATPase activity
BFX80_RS09630	COG1295	ribonuclease BN
BFX80_RS09650	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BFX80_RS09655	COG1687	branched-chain amino acid
BFX80_RS09660	COG0259	pyridoxamine-phosphate oxidase activity
BFX80_RS09670	COG0564	pseudouridine synthase activity
BFX80_RS09690	COG1042	CoA-binding domain protein
BFX80_RS09690	COG0045	succinate-CoA ligase (ADP-forming) activity
BFX80_RS09690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFX80_RS09710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFX80_RS09740	COG0243	molybdopterin cofactor binding
BFX80_RS09740	COG3383	formate dehydrogenase (NAD+) activity
BFX80_RS09745	COG0437	4 iron, 4 sulfur cluster binding
BFX80_RS09760	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFX80_RS09765	COG0303	'Molybdopterin
BFX80_RS09790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFX80_RS09795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFX80_RS09805	COG0709	Synthesizes selenophosphate from selenide and ATP
BFX80_RS09835	COG0154	amidase activity
BFX80_RS09840	COG1126	abc transporter atp-binding protein
BFX80_RS09845	COG0765	amino acid transport
BFX80_RS09850	COG0765	amino acid transport
BFX80_RS09875	COG1309	transcriptional regulator
BFX80_RS09885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFX80_RS09890	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BFX80_RS09890	COG3608	succinylglutamate desuccinylase aspartoacylase
BFX80_RS09895	COG0402	S-adenosylhomocysteine deaminase activity
BFX80_RS09910	COG2233	PERMEase
BFX80_RS09915	COG0737	Belongs to the 5'-nucleotidase family
BFX80_RS09925	COG1522	sequence-specific DNA binding
BFX80_RS09935	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFX80_RS09960	COG0252	asparaginase activity
BFX80_RS09995	COG1902	pentaerythritol trinitrate reductase activity
BFX80_RS09995	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFX80_RS10015	COG2351	hydroxyisourate hydrolase activity
BFX80_RS10030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BFX80_RS10040	COG1192	Involved in chromosome partitioning
BFX80_RS10045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BFX80_RS10055	COG1757	Na H antiporter
BFX80_RS10065	COG0640	Transcriptional regulator
BFX80_RS10070	COG0616	signal peptide processing
BFX80_RS10090	COG0328	RNA-DNA hybrid ribonuclease activity
BFX80_RS10095	COG2226	methyltransferase
BFX80_RS10100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFX80_RS10105	COG0741	lytic transglycosylase activity
BFX80_RS10110	COG4166	transmembrane transport
BFX80_RS10115	COG4174	ABC transporter (Permease)
BFX80_RS10120	COG4239	(ABC) transporter, permease
BFX80_RS10125	COG4172	Belongs to the ABC transporter superfamily
BFX80_RS10155	COG4615	Cyclic peptide transporter
BFX80_RS10160	COG0417	DNA replication proofreading
BFX80_RS10190	COG2132	Multicopper oxidase
BFX80_RS10225	COG3530	Putative quorum-sensing-regulated virulence factor
BFX80_RS10240	COG0640	Transcriptional regulator
BFX80_RS10245	COG1393	Belongs to the ArsC family
BFX80_RS10250	COG0431	NADPH-dependent FMN reductase
BFX80_RS10270	COG0583	DNA-binding transcription factor activity
BFX80_RS10290	COG0625	glutathione transferase activity
BFX80_RS10295	COG1971	Probably functions as a manganese efflux pump
BFX80_RS10320	COG5006	permease, DMT superfamily
BFX80_RS10330	COG4172	Belongs to the ABC transporter superfamily
BFX80_RS10335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFX80_RS10370	COG2807	transmembrane transport
BFX80_RS10375	COG2207	Transcriptional regulator
BFX80_RS10395	COG0235	Class ii aldolase
BFX80_RS10400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFX80_RS10405	COG1902	pentaerythritol trinitrate reductase activity
BFX80_RS10425	COG1252	NADH dehydrogenase
BFX80_RS10430	COG1802	Transcriptional regulator
BFX80_RS10440	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BFX80_RS10445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS10455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS10465	COG0583	DNA-binding transcription factor activity
BFX80_RS10480	COG4336	lyase activity
BFX80_RS10495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS10520	COG0604	alcohol dehydrogenase
BFX80_RS10535	COG0583	DNA-binding transcription factor activity
BFX80_RS10555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFX80_RS10570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFX80_RS10570	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFX80_RS10585	COG0004	ammonium transporteR
BFX80_RS10595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFX80_RS10605	COG0069	glutamate synthase activity
BFX80_RS10610	COG2218	PFAM glutamate synthase alpha subunit domain protein
BFX80_RS10615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BFX80_RS10630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFX80_RS10655	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BFX80_RS10670	COG3321	synthase
BFX80_RS10670	COG0604	alcohol dehydrogenase
BFX80_RS10675	COG0583	DNA-binding transcription factor activity
BFX80_RS10685	COG2391	methyltransferase activity
BFX80_RS10730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS10745	COG1396	sequence-specific DNA binding
BFX80_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS10915	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS10920	COG4948	Mandelate Racemase Muconate Lactonizing
BFX80_RS10925	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BFX80_RS10940	COG2084	Dehydrogenase
BFX80_RS10945	COG0583	DNA-binding transcription factor activity
BFX80_RS10950	COG0006	proline dipeptidase activity
BFX80_RS10965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS10970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS11020	COG0523	cobalamin synthesis protein
BFX80_RS11030	COG3718	enzyme involved in inositol metabolism
BFX80_RS11035	COG0673	inositol 2-dehydrogenase activity
BFX80_RS11040	COG1737	Transcriptional regulator
BFX80_RS11050	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFX80_RS11060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFX80_RS11065	COG3962	Belongs to the TPP enzyme family
BFX80_RS11080	COG1082	Xylose isomerase domain protein TIM barrel
BFX80_RS11085	COG2814	Major facilitator Superfamily
BFX80_RS11085	COG0477	Major facilitator Superfamily
BFX80_RS11095	COG2814	Major facilitator Superfamily
BFX80_RS11095	COG0477	Major facilitator Superfamily
BFX80_RS11100	COG1082	Xylose isomerase domain protein TIM barrel
BFX80_RS11105	COG0673	inositol 2-dehydrogenase activity
BFX80_RS11110	COG3962	Belongs to the TPP enzyme family
BFX80_RS11135	COG0673	inositol 2-dehydrogenase activity
BFX80_RS11140	COG1609	Transcriptional regulator
BFX80_RS11145	COG3237	CsbD-like
BFX80_RS11155	COG1653	transport
BFX80_RS11170	COG0366	Alpha amylase catalytic
BFX80_RS11175	COG3842	ATPase activity
BFX80_RS11180	COG0366	Alpha amylase catalytic
BFX80_RS11185	COG0366	Alpha amylase catalytic
BFX80_RS11190	COG1653	transport
BFX80_RS11195	COG0366	Alpha amylase catalytic
BFX80_RS11200	COG1609	Transcriptional regulator
BFX80_RS11205	COG0583	DNA-binding transcription factor activity
BFX80_RS11210	COG0235	Class ii aldolase
BFX80_RS11215	COG3314	Sporulation integral membrane protein YlbJ
BFX80_RS11235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFX80_RS11255	COG3459	Glycosyltransferase 36 associated
BFX80_RS11280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BFX80_RS11290	COG0583	DNA-binding transcription factor activity
BFX80_RS11295	COG1301	dicarboxylic acid transport
BFX80_RS11300	COG0436	Aminotransferase
BFX80_RS11305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFX80_RS11325	COG3284	Transcriptional regulator
BFX80_RS11345	COG1473	amidohydrolase
BFX80_RS11350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BFX80_RS11355	COG0583	DNA-binding transcription factor activity
BFX80_RS11405	COG0583	DNA-binding transcription factor activity
BFX80_RS11415	COG1794	racemase activity, acting on amino acids and derivatives
BFX80_RS11420	COG1301	dicarboxylic acid transport
BFX80_RS11430	COG1187	pseudouridine synthase activity
BFX80_RS11445	COG2962	Rard protein
BFX80_RS11450	COG1295	ribonuclease BN
BFX80_RS11455	COG1764	response to oxidative stress
BFX80_RS11495	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BFX80_RS11510	COG0189	ligase activity
BFX80_RS11510	COG4067	protein conserved in archaea
BFX80_RS11520	COG0217	transcriptional regulatory protein
BFX80_RS11535	COG2923	Belongs to the DsrF TusC family
BFX80_RS11540	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BFX80_RS11560	COG0513	Belongs to the DEAD box helicase family
BFX80_RS11565	COG3706	GGDEF domain
BFX80_RS11570	COG3263	regulation of cellular component size
BFX80_RS11580	COG1116	anion transmembrane transporter activity
BFX80_RS11585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFX80_RS11590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFX80_RS11600	COG0596	Alpha beta hydrolase
BFX80_RS11605	COG0583	DNA-binding transcription factor activity
BFX80_RS11610	COG2855	membrane
BFX80_RS11665	COG0583	DNA-binding transcription factor activity
BFX80_RS11670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BFX80_RS11675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BFX80_RS11680	COG1278	Cold shock
BFX80_RS11685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFX80_RS11690	COG1115	amino acid carrier protein
BFX80_RS11695	COG0509	glycine decarboxylation via glycine cleavage system
BFX80_RS11700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFX80_RS11700	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFX80_RS11720	COG0395	ABC-type sugar transport system, permease component
BFX80_RS11730	COG3842	ATPase activity
BFX80_RS11735	COG3842	ATPase activity
BFX80_RS11740	COG3284	Transcriptional regulator
BFX80_RS11750	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFX80_RS11760	COG3842	ATPase activity
BFX80_RS11775	COG0678	peroxiredoxin activity
BFX80_RS11775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFX80_RS11785	COG0617	tRNA 3'-terminal CCA addition
BFX80_RS11785	COG0517	IMP dehydrogenase activity
BFX80_RS11785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BFX80_RS11790	COG3048	D-serine ammonia-lyase activity
BFX80_RS11800	COG2186	Transcriptional regulator
BFX80_RS11805	COG0277	FAD linked oxidase domain protein
BFX80_RS11810	COG0277	FAD linked oxidase domain protein
BFX80_RS11815	COG0247	lactate metabolic process
BFX80_RS11820	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BFX80_RS11830	COG0667	Aldo Keto reductase
BFX80_RS11835	COG1070	Carbohydrate kinase
BFX80_RS11850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFX80_RS11855	COG3842	ATPase activity
BFX80_RS11865	COG1175	transmembrane transport
BFX80_RS11875	COG1653	transport
BFX80_RS11900	COG1280	lysine exporter protein (LysE YggA)
BFX80_RS11915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFX80_RS11945	COG1414	Transcriptional regulator
BFX80_RS11975	COG0668	transmembrane transport
BFX80_RS11995	COG0463	Glycosyl transferase, family 2
BFX80_RS12005	COG4890	Cyd operon protein YbgT
BFX80_RS12010	COG1294	oxidase, subunit
BFX80_RS12030	COG3047	cAMP biosynthetic process
BFX80_RS12040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFX80_RS12055	COG0400	carboxylic ester hydrolase activity
BFX80_RS12105	COG1126	abc transporter atp-binding protein
BFX80_RS12125	COG0189	ligase activity
BFX80_RS12125	COG4067	protein conserved in archaea
BFX80_RS12130	COG0189	ligase activity
BFX80_RS12160	COG0719	Fe-S assembly protein
BFX80_RS12165	COG0396	ATPase activity
BFX80_RS12170	COG0719	Fe-S assembly protein
BFX80_RS12175	COG1959	2 iron, 2 sulfur cluster binding
BFX80_RS12180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BFX80_RS12185	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BFX80_RS12190	COG0330	HflC and HflK could
BFX80_RS12195	COG0330	HflC and HflK could
BFX80_RS12200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFX80_RS12205	COG1923	regulation of RNA biosynthetic process
BFX80_RS12210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFX80_RS12215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFX80_RS12220	COG0860	N-Acetylmuramoyl-L-alanine amidase
BFX80_RS12225	COG0802	atpase or kinase
BFX80_RS12230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFX80_RS12230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BFX80_RS12240	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BFX80_RS12245	COG1162	GTPase activity
BFX80_RS12250	COG0308	aminopeptidase N
BFX80_RS12260	COG1929	Belongs to the glycerate kinase type-1 family
BFX80_RS12265	COG2996	Protein conserved in bacteria
BFX80_RS12270	COG1666	GTP binding
BFX80_RS12280	COG0189	ligase activity
BFX80_RS12305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFX80_RS12325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFX80_RS12335	COG2056	Na+-H+ antiporter family
BFX80_RS12340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFX80_RS12355	COG1280	lysine exporter protein (LysE YggA)
BFX80_RS12360	COG2353	YceI-like domain
BFX80_RS12365	COG3038	cytochrome b561
BFX80_RS12390	COG0285	dihydrofolate synthase activity
BFX80_RS12395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFX80_RS12400	COG0135	phosphoribosylanthranilate isomerase activity
BFX80_RS12405	COG0101	tRNA pseudouridine synthase activity
BFX80_RS12420	COG0473	3-isopropylmalate dehydrogenase activity
BFX80_RS12425	COG0066	3-isopropylmalate dehydratase activity
BFX80_RS12430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFX80_RS12440	COG3243	poly(R)-hydroxyalkanoic acid synthase
BFX80_RS12455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFX80_RS12465	COG1193	negative regulation of DNA recombination
BFX80_RS12480	COG0596	Alpha beta hydrolase
BFX80_RS12500	COG1131	(ABC) transporter
BFX80_RS12520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFX80_RS12530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BFX80_RS12540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BFX80_RS12555	COG0326	Molecular chaperone. Has ATPase activity
BFX80_RS12575	COG3339	Conserved Protein
BFX80_RS12580	COG0741	lytic transglycosylase activity
BFX80_RS12595	COG1280	lysine exporter protein (LysE YggA)
BFX80_RS12600	COG3932	Exopolysaccharide synthesis, ExoD
BFX80_RS12625	COG1278	Cold shock
BFX80_RS12640	COG0330	HflC and HflK could
BFX80_RS12650	COG1597	lipid kinase activity
BFX80_RS12655	COG2814	Major facilitator Superfamily
BFX80_RS12695	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BFX80_RS12700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFX80_RS12705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BFX80_RS12705	COG1565	acr, cog1565
BFX80_RS12710	COG1966	Carbon starvation protein
BFX80_RS12720	COG0003	Pfam Anion-transporting ATPase
BFX80_RS12725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFX80_RS12730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFX80_RS12735	COG2995	paraquat-inducible protein a
BFX80_RS12740	COG3008	intermembrane lipid transfer
BFX80_RS12740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFX80_RS12750	COG3134	Outer membrane lipoprotein
BFX80_RS12780	COG2807	transmembrane transport
BFX80_RS12795	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BFX80_RS12800	COG0252	asparaginase activity
BFX80_RS12805	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFX80_RS12810	COG3956	TIGRFAM MazG family protein
BFX80_RS12815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFX80_RS12820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFX80_RS12830	COG2205	protein histidine kinase activity
BFX80_RS12830	COG5002	protein histidine kinase activity
BFX80_RS12830	COG0784	Response regulator, receiver
BFX80_RS12835	COG0736	holo-[acyl-carrier-protein] synthase activity
BFX80_RS12850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BFX80_RS12855	COG0571	ribonuclease III activity
BFX80_RS12865	COG0481	GTPase activity
BFX80_RS12870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFX80_RS12880	COG4628	conserved protein (DUF2132)
BFX80_RS12895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFX80_RS12900	COG1199	ATP-dependent helicase activity
BFX80_RS12915	COG0708	Exodeoxyribonuclease III
BFX80_RS12930	COG0848	biopolymer transport protein
BFX80_RS12965	COG1301	dicarboxylic acid transport
BFX80_RS12975	COG0210	DNA helicase
BFX80_RS12985	COG0084	hydrolase, TatD family'
BFX80_RS13000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFX80_RS13005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFX80_RS13010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFX80_RS13015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFX80_RS13020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFX80_RS13030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BFX80_RS13035	COG0416	fatty acid biosynthetic process
BFX80_RS13040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BFX80_RS13045	COG1399	metal-binding, possibly nucleic acid-binding protein
BFX80_RS13050	COG0424	maF-like protein
BFX80_RS13055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFX80_RS13055	COG0616	signal peptide processing
BFX80_RS13060	COG0546	phosphoglycolate phosphatase activity
BFX80_RS13065	COG0564	pseudouridine synthase activity
BFX80_RS13070	COG1530	ribonuclease E activity
BFX80_RS13080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFX80_RS13090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BFX80_RS13095	COG2835	tetraacyldisaccharide 4'-kinase activity
BFX80_RS13100	COG1663	tetraacyldisaccharide 4'-kinase activity
BFX80_RS13110	COG0848	biopolymer transport protein
BFX80_RS13115	COG0811	peptide transport
BFX80_RS13130	COG1136	(ABC) transporter
BFX80_RS13135	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFX80_RS13145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFX80_RS13160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFX80_RS13170	COG1477	protein flavinylation
BFX80_RS13175	COG2871	sodium ion transport
BFX80_RS13180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFX80_RS13195	COG1805	sodium ion transport
BFX80_RS13200	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFX80_RS13210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFX80_RS13220	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BFX80_RS13225	COG0668	transmembrane transport
BFX80_RS13230	COG1472	Belongs to the glycosyl hydrolase 3 family
BFX80_RS13235	COG1376	ErfK ybiS ycfS ynhG family protein
BFX80_RS13240	COG1309	transcriptional regulator
BFX80_RS13245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFX80_RS13265	COG0469	pyruvate kinase activity
BFX80_RS13270	COG1803	Methylglyoxal synthase
BFX80_RS13285	COG1028	Short-chain dehydrogenase reductase Sdr
BFX80_RS13300	COG0439	Biotin carboxylase
BFX80_RS13310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BFX80_RS13315	COG0321	lipoyl(octanoyl) transferase activity
BFX80_RS13320	COG2921	Belongs to the UPF0250 family
BFX80_RS13325	COG1686	Belongs to the peptidase S11 family
BFX80_RS13330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BFX80_RS13335	COG2951	lytic endotransglycosylase activity
BFX80_RS13340	COG0772	Belongs to the SEDS family
BFX80_RS13345	COG0768	penicillin binding
BFX80_RS13350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFX80_RS13360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFX80_RS13365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFX80_RS13380	COG0586	Pfam SNARE associated Golgi protein
BFX80_RS13400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFX80_RS13405	COG0205	6-phosphofructokinase activity
BFX80_RS13430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BFX80_RS13435	COG0511	ligase activity, forming carbon-carbon bonds
BFX80_RS13445	COG2264	protein methyltransferase activity
BFX80_RS13460	COG0138	bifunctional purine biosynthesis protein purh
BFX80_RS13490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BFX80_RS13495	COG0302	gtp cyclohydrolase
BFX80_RS13500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BFX80_RS13510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFX80_RS13515	COG0156	8-amino-7-oxononanoate synthase activity
BFX80_RS13520	COG0596	Alpha beta hydrolase
BFX80_RS13525	COG1073	alpha beta
BFX80_RS13525	COG2226	methyltransferase
BFX80_RS13530	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BFX80_RS13545	COG1742	UPF0060 membrane protein
BFX80_RS13550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFX80_RS13560	COG1960	acyl-CoA dehydrogenase activity
BFX80_RS13565	COG1648	precorrin-2 dehydrogenase activity
BFX80_RS13565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFX80_RS13570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BFX80_RS13575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BFX80_RS13585	COG0247	lactate metabolic process
BFX80_RS13585	COG0277	FAD linked oxidase domain protein
BFX80_RS13595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFX80_RS13600	COG4206	TonB-dependent receptor
BFX80_RS13605	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BFX80_RS13620	COG0284	orotidine-5'-phosphate decarboxylase activity
BFX80_RS13630	COG1047	Peptidyl-prolyl cis-trans
BFX80_RS13640	COG2814	Major facilitator Superfamily
BFX80_RS13665	COG2244	polysaccharide biosynthetic process
BFX80_RS13670	COG1215	transferase activity, transferring glycosyl groups
BFX80_RS13685	COG0653	protein targeting
BFX80_RS13690	COG2040	homocysteine
BFX80_RS13700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFX80_RS13725	COG1737	Transcriptional regulator
BFX80_RS13730	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BFX80_RS13735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BFX80_RS13735	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BFX80_RS13745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BFX80_RS13770	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BFX80_RS13775	COG0237	dephospho-CoA kinase activity
BFX80_RS13785	COG0352	thiamine-phosphate diphosphorylase activity
BFX80_RS13790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BFX80_RS13795	COG0653	protein targeting
BFX80_RS13810	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BFX80_RS13830	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFX80_RS13835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFX80_RS13840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFX80_RS13845	COG0772	Belongs to the SEDS family
BFX80_RS13850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BFX80_RS13855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFX80_RS13860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFX80_RS13880	COG0275	rRNA processing
BFX80_RS13900	COG0792	nuclease activity
BFX80_RS13905	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFX80_RS13910	COG2823	Periplasmic or secreted lipoprotein
BFX80_RS13915	COG2969	positive regulation of protein catabolic process
BFX80_RS13920	COG0625	glutathione transferase activity
BFX80_RS13925	COG2857	Cytochrome c1
BFX80_RS13930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BFX80_RS13935	COG0723	plastoquinol--plastocyanin reductase activity
BFX80_RS13940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BFX80_RS13945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFX80_RS13950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BFX80_RS13965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFX80_RS13970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFX80_RS13975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BFX80_RS13980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFX80_RS13985	COG5007	Belongs to the BolA IbaG family
BFX80_RS14000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFX80_RS14005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFX80_RS14010	COG1127	ABC transporter
BFX80_RS14025	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BFX80_RS14035	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BFX80_RS14040	COG1137	ATPase activity
BFX80_RS14045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BFX80_RS14060	COG1660	Displays ATPase and GTPase activities
BFX80_RS14065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFX80_RS14075	COG0312	modulator of DNA gyrase
BFX80_RS14080	COG3028	Belongs to the UPF0307 family
BFX80_RS14085	COG0312	modulator of DNA gyrase
BFX80_RS14095	COG1530	ribonuclease E activity
BFX80_RS14100	COG0424	maF-like protein
BFX80_RS14105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BFX80_RS14110	COG1792	Involved in formation and maintenance of cell shape
BFX80_RS14115	COG1077	Cell shape determining protein MreB Mrl
BFX80_RS14120	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFX80_RS14125	COG0154	amidase activity
BFX80_RS14130	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFX80_RS14140	COG1012	belongs to the aldehyde dehydrogenase family
BFX80_RS14145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFX80_RS14150	COG0174	glutamine synthetase
BFX80_RS14155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS14170	COG1177	transmembrane transport
BFX80_RS14175	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFX80_RS14180	COG3842	ATPase activity
BFX80_RS14185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS14190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFX80_RS14200	COG2890	protein-(glutamine-N5) methyltransferase activity
BFX80_RS14205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFX80_RS14210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BFX80_RS14220	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BFX80_RS14225	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BFX80_RS14240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BFX80_RS14245	COG0193	aminoacyl-tRNA hydrolase activity
BFX80_RS14255	COG0583	DNA-binding transcription factor activity
BFX80_RS14270	COG1362	aminopeptidase activity
BFX80_RS14305	COG1309	transcriptional regulator
BFX80_RS14315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BFX80_RS14340	COG1175	transmembrane transport
BFX80_RS14345	COG0395	ABC-type sugar transport system, permease component
BFX80_RS14350	COG3842	ATPase activity
BFX80_RS14355	COG0584	glycerophosphoryl diester phosphodiesterase
BFX80_RS14360	COG1349	DNA-binding transcription factor activity
BFX80_RS14370	COG0134	indole-3-glycerol-phosphate synthase activity
BFX80_RS14375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFX80_RS14390	COG0546	phosphoglycolate phosphatase activity
BFX80_RS14395	COG1252	NADH dehydrogenase
BFX80_RS14400	COG2827	Endonuclease containing a URI domain
BFX80_RS14405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BFX80_RS14410	COG0405	Gamma-glutamyltransferase
BFX80_RS14425	COG0500	methyltransferase
BFX80_RS14430	COG4991	sh3 domain protein
BFX80_RS14435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFX80_RS14440	COG1702	phosphate starvation-inducible protein PhoH
BFX80_RS14445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFX80_RS14450	COG4535	Mg2 and Co2 transporter CorC
BFX80_RS14475	COG0495	leucyl-tRNA aminoacylation
BFX80_RS14485	COG1466	dna polymerase III delta subunit
BFX80_RS14500	COG0183	Belongs to the thiolase family
BFX80_RS14505	COG1024	Enoyl-CoA hydratase
BFX80_RS14505	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFX80_RS14515	COG1846	Transcriptional regulator
BFX80_RS14525	COG0589	response to stress
BFX80_RS14530	COG0488	(ABC) transporter
BFX80_RS14545	COG0513	Belongs to the DEAD box helicase family
BFX80_RS14560	COG1840	ABC-type Fe3 transport system, periplasmic component
BFX80_RS14565	COG3101	peptidyl-lysine hydroxylation
BFX80_RS14595	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BFX80_RS14615	COG0501	Belongs to the peptidase M48B family
BFX80_RS14620	COG1704	LemA family
BFX80_RS14625	COG2079	MmgE PrpD family protein
BFX80_RS14635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BFX80_RS14640	COG0372	Belongs to the citrate synthase family
BFX80_RS14645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BFX80_RS14650	COG1802	Transcriptional regulator
BFX80_RS14660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BFX80_RS14665	COG0175	sulfate reduction
BFX80_RS14670	COG0583	DNA-binding transcription factor activity
BFX80_RS14675	COG0730	response to heat
BFX80_RS14680	COG3118	belongs to the thioredoxin family
BFX80_RS14685	COG0628	permease
BFX80_RS14690	COG1960	acyl-CoA dehydrogenase activity
BFX80_RS14700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFX80_RS14705	COG1309	transcriptional regulator
BFX80_RS14710	COG0183	Belongs to the thiolase family
BFX80_RS14715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFX80_RS14720	COG0573	inorganic phosphate transmembrane transporter activity
BFX80_RS14725	COG0573	inorganic phosphate transmembrane transporter activity
BFX80_RS14735	COG2814	Major facilitator Superfamily
BFX80_RS14755	COG2853	Lipoprotein
BFX80_RS14765	COG1643	Atp-dependent helicase
BFX80_RS14770	COG0318	PFAM AMP-dependent synthetase and ligase
BFX80_RS14780	COG0121	glutamine amidotransferase
BFX80_RS14825	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFX80_RS14830	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFX80_RS14840	COG2814	Major facilitator Superfamily
BFX80_RS14845	COG3106	COG3106 Predicted ATPase
BFX80_RS14850	COG3768	UPF0283 membrane protein
BFX80_RS14855	COG0673	inositol 2-dehydrogenase activity
BFX80_RS14865	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BFX80_RS14890	COG0584	glycerophosphoryl diester phosphodiesterase
BFX80_RS14905	COG0045	succinate-CoA ligase (ADP-forming) activity
BFX80_RS14930	COG1053	succinate dehydrogenase
BFX80_RS14935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BFX80_RS14950	COG2084	Dehydrogenase
BFX80_RS14965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFX80_RS14970	COG4988	ABC transporter
BFX80_RS14975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFX80_RS14985	COG0583	DNA-binding transcription factor activity
BFX80_RS15005	COG1309	transcriptional regulator
BFX80_RS15010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFX80_RS15015	COG3104	oligopeptide transport
BFX80_RS15060	COG1914	H( )-stimulated, divalent metal cation uptake system
BFX80_RS15065	COG2205	protein histidine kinase activity
BFX80_RS15075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFX80_RS15080	COG1074	ATP-dependent DNA helicase activity
BFX80_RS15085	COG1074	ATP-dependent DNA helicase activity
BFX80_RS15090	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BFX80_RS15105	COG0420	3'-5' exonuclease activity
BFX80_RS15115	COG1515	deoxyribonuclease V activity
BFX80_RS15130	COG1671	Belongs to the UPF0178 family
BFX80_RS15135	COG0435	Glutathione S-transferase
BFX80_RS15140	COG0583	DNA-binding transcription factor activity
BFX80_RS15145	COG0739	heme binding
BFX80_RS15195	COG0076	glutamate decarboxylase activity
BFX80_RS15200	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BFX80_RS15215	COG1120	ATPase activity
BFX80_RS15255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFX80_RS15265	COG1757	Na H antiporter
BFX80_RS15270	COG1017	nitric oxide dioxygenase activity
BFX80_RS15270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFX80_RS15280	COG0109	protoheme IX farnesyltransferase activity
BFX80_RS15285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFX80_RS15290	COG1845	cytochrome c oxidase, subunit III
BFX80_RS15305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BFX80_RS15315	COG3383	formate dehydrogenase (NAD+) activity
BFX80_RS15325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS15345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BFX80_RS15350	COG2181	nitrate reductase activity
BFX80_RS15350	COG0247	lactate metabolic process
BFX80_RS15355	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFX80_RS15355	COG1902	pentaerythritol trinitrate reductase activity
BFX80_RS15370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFX80_RS15390	COG0583	DNA-binding transcription factor activity
BFX80_RS15395	COG1953	Uracil, thiamine, allantoin
BFX80_RS15420	COG1309	transcriptional regulator
BFX80_RS15425	COG1116	anion transmembrane transporter activity
BFX80_RS15425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFX80_RS15435	COG2223	nitrite transmembrane transporter activity
BFX80_RS15445	COG0513	Belongs to the DEAD box helicase family
BFX80_RS15480	COG0492	ferredoxin-NADP+ reductase activity
BFX80_RS15485	COG0564	pseudouridine synthase activity
BFX80_RS15500	COG0519	Catalyzes the synthesis of GMP from XMP
BFX80_RS15500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFX80_RS15515	COG0642	Histidine kinase
BFX80_RS15520	COG0745	RESPONSE REGULATOR receiver
BFX80_RS15545	COG2204	response regulator
BFX80_RS15555	COG2205	protein histidine kinase activity
BFX80_RS15560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFX80_RS15560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BFX80_RS15565	COG0306	phosphate transporter
BFX80_RS15570	COG1392	Phosphate transport regulator
BFX80_RS15580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFX80_RS15590	COG0009	L-threonylcarbamoyladenylate synthase
BFX80_RS15595	COG0613	PHP domain protein
BFX80_RS15600	COG2917	probably involved in intracellular septation
BFX80_RS15605	COG2350	Protein conserved in bacteria
BFX80_RS15610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFX80_RS15610	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BFX80_RS15615	COG4565	transcriptional regulatory protein
BFX80_RS15620	COG3290	protein histidine kinase activity
BFX80_RS15635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFX80_RS15640	COG3115	cell septum assembly
BFX80_RS15660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFX80_RS15665	COG1138	Cytochrome C-type biogenesis protein
BFX80_RS15670	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BFX80_RS15695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFX80_RS15700	COG1739	Uncharacterized protein family UPF0029
BFX80_RS15720	COG0583	DNA-binding transcription factor activity
BFX80_RS15725	COG1278	Cold shock
BFX80_RS15735	COG2205	protein histidine kinase activity
BFX80_RS15740	COG0745	RESPONSE REGULATOR receiver
BFX80_RS15745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFX80_RS15745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFX80_RS15750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFX80_RS15755	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BFX80_RS15770	COG0666	response to abiotic stimulus
BFX80_RS15775	COG2205	protein histidine kinase activity
BFX80_RS15800	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BFX80_RS15805	COG0537	adenosine 5'-monophosphoramidase activity
BFX80_RS15815	COG3954	Phosphoribulokinase
BFX80_RS15825	COG0151	Belongs to the GarS family
BFX80_RS15840	COG0415	Belongs to the DNA photolyase family
BFX80_RS15845	COG2111	Na H antiporter
BFX80_RS15845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BFX80_RS15850	COG1006	Multisubunit Na H antiporter MnhC subunit
BFX80_RS15855	COG0651	ATP synthesis coupled electron transport
BFX80_RS15860	COG1863	multisubunit Na H antiporter MnhE subunit
BFX80_RS15865	COG2212	antiporter activity
BFX80_RS15870	COG1320	monovalent cation:proton antiporter activity
BFX80_RS15875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BFX80_RS15880	COG3046	protein related to deoxyribodipyrimidine photolyase
BFX80_RS15895	COG2200	EAL domain
BFX80_RS15895	COG2203	Gaf domain
BFX80_RS15895	COG2199	diguanylate cyclase activity
BFX80_RS15905	COG0305	Participates in initiation and elongation during chromosome replication
BFX80_RS15910	COG0359	binds to the 23S rRNA
BFX80_RS15920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFX80_RS15925	COG0360	Binds together with S18 to 16S ribosomal RNA
BFX80_RS15930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFX80_RS15935	COG0557	exoribonuclease II activity
BFX80_RS15975	COG2719	SpoVR family
BFX80_RS15980	COG2718	Belongs to the UPF0229 family
BFX80_RS15985	COG2766	serine protein kinase
BFX80_RS16000	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFX80_RS16000	COG1902	pentaerythritol trinitrate reductase activity
BFX80_RS16040	COG3278	Belongs to the heme-copper respiratory oxidase family
BFX80_RS16055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFX80_RS16070	COG3220	belongs to the UPF0276 family
BFX80_RS16085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BFX80_RS16125	COG0795	lipopolysaccharide-transporting ATPase activity
BFX80_RS16130	COG0795	lipopolysaccharide-transporting ATPase activity
BFX80_RS16140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFX80_RS16145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFX80_RS16155	COG2205	protein histidine kinase activity
BFX80_RS16160	COG0525	valine-tRNA ligase activity
BFX80_RS16170	COG0671	phosphoesterase, PA-phosphatase related
BFX80_RS16175	COG3706	GGDEF domain
BFX80_RS16180	COG0346	lactoylglutathione lyase activity
BFX80_RS16185	COG0243	molybdopterin cofactor binding
BFX80_RS16195	COG1054	Belongs to the UPF0176 family
BFX80_RS16200	COG0583	DNA-binding transcription factor activity
BFX80_RS16260	COG4191	Histidine kinase
BFX80_RS16275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFX80_RS16280	COG0783	Belongs to the Dps family
BFX80_RS16300	COG3220	belongs to the UPF0276 family
BFX80_RS16315	COG0693	protein deglycase activity
BFX80_RS16325	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFX80_RS16330	COG1444	tRNA N-acetyltransferase activity
BFX80_RS16345	COG0672	)-iron permease
BFX80_RS16370	COG0583	DNA-binding transcription factor activity
BFX80_RS16375	COG4145	pantothenate transmembrane transporter activity
BFX80_RS16380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFX80_RS16420	COG2175	clavaminate synthase activity
BFX80_RS16440	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFX80_RS16445	COG2204	response regulator
BFX80_RS16450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFX80_RS16450	COG0666	response to abiotic stimulus
BFX80_RS16470	COG1166	arginine decarboxylase activity
BFX80_RS16475	COG0179	Fumarylacetoacetate (FAA) hydrolase
BFX80_RS16480	COG5285	phytanoyl-CoA dioxygenase
BFX80_RS16485	COG1462	curli production assembly transport component CsgG
BFX80_RS16500	COG2204	response regulator
BFX80_RS16530	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BFX80_RS16535	COG1194	a g-specific adenine glycosylase
BFX80_RS16550	COG0131	Imidazoleglycerol-phosphate dehydratase
BFX80_RS16555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFX80_RS16560	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BFX80_RS16565	COG0107	imidazoleglycerol-phosphate synthase activity
BFX80_RS16575	COG3068	Protein conserved in bacteria
BFX80_RS16590	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BFX80_RS16615	COG1902	pentaerythritol trinitrate reductase activity
BFX80_RS16620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFX80_RS16625	COG0346	lactoylglutathione lyase activity
BFX80_RS16645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFX80_RS16650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BFX80_RS16680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFX80_RS16685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFX80_RS16685	COG2813	Specifically methylates the guanine in position
BFX80_RS16690	COG1607	acyl-coa hydrolase
BFX80_RS16710	COG1489	DNA binding
BFX80_RS16715	COG0436	Aminotransferase
BFX80_RS16720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFX80_RS16725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFX80_RS16735	COG0617	tRNA 3'-terminal CCA addition
BFX80_RS16745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BFX80_RS16750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BFX80_RS16755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BFX80_RS16765	COG1185	polyribonucleotide nucleotidyltransferase activity
BFX80_RS16770	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFX80_RS16775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFX80_RS16780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFX80_RS16785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFX80_RS16790	COG0195	Participates in both transcription termination and antitermination
BFX80_RS16795	COG0779	Required for maturation of 30S ribosomal subunits
BFX80_RS16810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFX80_RS16815	COG0149	triose-phosphate isomerase activity
BFX80_RS16825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BFX80_RS16830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFX80_RS16835	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BFX80_RS16865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFX80_RS16875	COG0484	heat shock protein binding
BFX80_RS16880	COG0443	Heat shock 70 kDa protein
BFX80_RS16885	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFX80_RS16890	COG0497	DNA recombination
BFX80_RS16900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFX80_RS16910	COG2867	negative regulation of translational initiation
BFX80_RS16915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BFX80_RS16925	COG1120	ATPase activity
BFX80_RS16930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFX80_RS16935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFX80_RS16940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFX80_RS16945	COG0668	transmembrane transport
BFX80_RS16960	COG2959	enzyme of heme biosynthesis
BFX80_RS16970	COG0181	hydroxymethylbilane synthase activity
BFX80_RS16975	COG0165	Argininosuccinate lyase
BFX80_RS16985	COG0019	diaminopimelate decarboxylase activity
BFX80_RS16990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BFX80_RS17000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BFX80_RS17005	COG1011	Hydrolase
BFX80_RS17015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BFX80_RS17040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS17045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFX80_RS17050	COG1490	D-aminoacyl-tRNA deacylase activity
BFX80_RS17055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFX80_RS17060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFX80_RS17065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFX80_RS17080	COG1238	metal cluster binding
BFX80_RS17085	COG0604	alcohol dehydrogenase
BFX80_RS17085	COG3321	synthase
BFX80_RS17095	COG0488	(ABC) transporter
BFX80_RS17105	COG0545	Peptidyl-prolyl cis-trans isomerase
BFX80_RS17110	COG1999	signal sequence binding
BFX80_RS17125	COG2226	methyltransferase
BFX80_RS17130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFX80_RS17145	COG2363	Small membrane protein
BFX80_RS17155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BFX80_RS17170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFX80_RS17180	COG0606	chelatase, subunit chli
BFX80_RS17200	COG0004	ammonium transporteR
BFX80_RS17215	COG0583	DNA-binding transcription factor activity
BFX80_RS17230	COG1126	abc transporter atp-binding protein
BFX80_RS17235	COG0765	amino acid transport
BFX80_RS17240	COG4597	amino acid ABC transporter
BFX80_RS17245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFX80_RS17260	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BFX80_RS17265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFX80_RS17270	COG1272	protein, Hemolysin III
BFX80_RS17280	COG0625	glutathione transferase activity
BFX80_RS17285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BFX80_RS17290	COG0142	geranyltranstransferase activity
BFX80_RS17295	COG1722	exodeoxyribonuclease VII activity
BFX80_RS17300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFX80_RS17305	COG1942	4-Oxalocrotonate Tautomerase
BFX80_RS17315	COG0540	Belongs to the ATCase OTCase family
BFX80_RS17320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BFX80_RS17325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFX80_RS17330	COG1678	Uncharacterized ACR, COG1678
BFX80_RS17340	COG0189	ligase activity
BFX80_RS17345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFX80_RS17350	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BFX80_RS17355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFX80_RS17360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BFX80_RS17365	COG4942	peptidase
BFX80_RS17370	COG0793	Belongs to the peptidase S41A family
BFX80_RS17375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFX80_RS17380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFX80_RS17385	COG0006	proline dipeptidase activity
BFX80_RS17405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFX80_RS17410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFX80_RS17415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFX80_RS17430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFX80_RS17435	COG1349	DNA-binding transcription factor activity
BFX80_RS17440	COG1519	Transferase
BFX80_RS17445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BFX80_RS17445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BFX80_RS17450	COG0859	PFAM glycosyl transferase family 9
BFX80_RS17455	COG3642	lipopolysaccharide core region biosynthetic process
BFX80_RS17465	COG0297	glycogen (starch) synthase activity
BFX80_RS17480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFX80_RS17485	COG0752	glycyl-tRNA synthetase alpha subunit
BFX80_RS17490	COG0751	glycine-tRNA ligase activity
BFX80_RS17495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFX80_RS17515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFX80_RS17520	COG0592	DNA-directed DNA polymerase activity
BFX80_RS17525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFX80_RS17535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BFX80_RS17540	COG0594	ribonuclease P activity
BFX80_RS17545	COG0706	membrane insertase activity
BFX80_RS17550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFX80_RS17555	COG1132	(ABC) transporter
BFX80_RS17560	COG1132	(ABC) transporter
BFX80_RS17565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BFX80_RS17570	COG2885	chlorophyll binding
BFX80_RS17575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFX80_RS17580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFX80_RS17585	COG2197	response regulator
BFX80_RS17630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFX80_RS17640	COG1981	membrane
BFX80_RS17650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFX80_RS17655	COG0316	Belongs to the HesB IscA family
BFX80_RS17660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFX80_RS17665	COG0765	amino acid transport
BFX80_RS17670	COG1126	abc transporter atp-binding protein
BFX80_RS17675	COG0445	tRNA wobble uridine modification
BFX80_RS17680	COG0357	Ribosomal RNA small subunit methyltransferase G
BFX80_RS17685	COG1192	Involved in chromosome partitioning
BFX80_RS17690	COG1475	DNA binding
BFX80_RS17695	COG3312	ion transport