locus-tag	class	description
KCTCHS21_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCTCHS21_RS00010	COG0592	DNA-directed DNA polymerase activity
KCTCHS21_RS00015	COG2501	S4 domain
KCTCHS21_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCTCHS21_RS00030	COG0187	DNA topoisomerase II activity
KCTCHS21_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCTCHS21_RS00045	COG3437	response regulator, receiver
KCTCHS21_RS00090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCTCHS21_RS00100	COG4191	Histidine kinase
KCTCHS21_RS00135	COG1309	transcriptional regulator
KCTCHS21_RS00140	COG1033	growth of symbiont in host cell
KCTCHS21_RS00140	COG2409	Drug exporters of the RND superfamily
KCTCHS21_RS00145	COG1982	Orn Lys Arg decarboxylase major
KCTCHS21_RS00155	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCTCHS21_RS00160	COG3870	Protein conserved in bacteria
KCTCHS21_RS00165	COG1728	Protein conserved in bacteria
KCTCHS21_RS00170	COG0470	DNA polymerase III
KCTCHS21_RS00175	COG1774	PSP1 C-terminal conserved region
KCTCHS21_RS00180	COG4467	Involved in initiation control of chromosome replication
KCTCHS21_RS00185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KCTCHS21_RS00190	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCTCHS21_RS00195	COG2002	toxin-antitoxin pair type II binding
KCTCHS21_RS00200	COG1078	dGTPase activity
KCTCHS21_RS00205	COG0084	hydrolase, TatD family'
KCTCHS21_RS00210	COG3584	3D domain protein
KCTCHS21_RS00210	COG3583	domain protein
KCTCHS21_RS00225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCTCHS21_RS00235	COG4466	Protein conserved in bacteria
KCTCHS21_RS00245	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCTCHS21_RS00250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCTCHS21_RS00255	COG0251	oxidation-reduction process
KCTCHS21_RS00260	COG2088	sporulation resulting in formation of a cellular spore
KCTCHS21_RS00265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCTCHS21_RS00270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCTCHS21_RS00275	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KCTCHS21_RS00295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCTCHS21_RS00300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCTCHS21_RS00305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCTCHS21_RS00310	COG2011	ABC-type metal ion transport system permease component
KCTCHS21_RS00315	COG1464	Belongs to the NlpA lipoprotein family
KCTCHS21_RS00320	COG2002	toxin-antitoxin pair type II binding
KCTCHS21_RS00325	COG2244	polysaccharide biosynthetic process
KCTCHS21_RS00330	COG3956	TIGRFAM MazG family protein
KCTCHS21_RS00340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KCTCHS21_RS00345	COG2706	6-phosphogluconolactonase activity
KCTCHS21_RS00365	COG1098	S1 RNA binding domain
KCTCHS21_RS00370	COG2208	phosphoserine phosphatase activity
KCTCHS21_RS00385	COG0515	serine threonine protein kinase
KCTCHS21_RS00390	COG0037	tRNA processing
KCTCHS21_RS00400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCTCHS21_RS00405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KCTCHS21_RS00410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KCTCHS21_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCTCHS21_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCTCHS21_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCTCHS21_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCTCHS21_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCTCHS21_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
KCTCHS21_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCTCHS21_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCTCHS21_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCTCHS21_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCTCHS21_RS00470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCTCHS21_RS00475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCTCHS21_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KCTCHS21_RS00515	COG0516	GMP reductase activity
KCTCHS21_RS00515	COG0517	IMP dehydrogenase activity
KCTCHS21_RS00520	COG1686	Belongs to the peptidase S11 family
KCTCHS21_RS00555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS00565	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KCTCHS21_RS00565	COG0662	Cupin 2, conserved barrel domain protein
KCTCHS21_RS00580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCTCHS21_RS00585	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCTCHS21_RS00595	COG2204	response regulator
KCTCHS21_RS00600	COG2972	Histidine kinase
KCTCHS21_RS00610	COG1175	transmembrane transport
KCTCHS21_RS00615	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS00620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS00625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS00630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS00775	COG1361	Conserved repeat domain
KCTCHS21_RS00790	COG0582	viral genome integration into host DNA
KCTCHS21_RS00805	COG3800	Transcriptional regulator
KCTCHS21_RS00805	COG1396	sequence-specific DNA binding
KCTCHS21_RS00810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCTCHS21_RS00835	COG5492	domain, Protein
KCTCHS21_RS00835	COG4932	domain protein
KCTCHS21_RS00915	COG1136	(ABC) transporter
KCTCHS21_RS00920	COG5002	protein histidine kinase activity
KCTCHS21_RS00925	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS00935	COG0590	tRNA wobble adenosine to inosine editing
KCTCHS21_RS00950	COG1360	Flagellar Motor Protein
KCTCHS21_RS00955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCTCHS21_RS00965	COG2154	pterin-4-alpha-carbinolamine dehydratase
KCTCHS21_RS00980	COG0738	Major facilitator superfamily
KCTCHS21_RS01065	COG1361	Conserved repeat domain
KCTCHS21_RS01065	COG3266	domain, Protein
KCTCHS21_RS01065	COG2911	Protein conserved in bacteria
KCTCHS21_RS01070	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS01095	COG0653	protein targeting
KCTCHS21_RS01110	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS01120	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS01140	COG0116	Belongs to the methyltransferase superfamily
KCTCHS21_RS01150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS01160	COG2207	Transcriptional regulator
KCTCHS21_RS01200	COG3850	Histidine kinase
KCTCHS21_RS01200	COG5002	protein histidine kinase activity
KCTCHS21_RS01205	COG0577	efflux transmembrane transporter activity
KCTCHS21_RS01210	COG1136	(ABC) transporter
KCTCHS21_RS01215	COG1378	Sugar-specific transcriptional regulator TrmB
KCTCHS21_RS01220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KCTCHS21_RS01230	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS01240	COG0534	Mate efflux family protein
KCTCHS21_RS01245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCTCHS21_RS01250	COG1408	metallophosphoesterase
KCTCHS21_RS01255	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS01265	COG4209	transmembrane transport
KCTCHS21_RS01270	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS01280	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KCTCHS21_RS01290	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS01295	COG0584	glycerophosphoryl diester phosphodiesterase
KCTCHS21_RS01300	COG4209	transmembrane transport
KCTCHS21_RS01310	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS01320	COG0534	Mate efflux family protein
KCTCHS21_RS01335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCTCHS21_RS01350	COG3655	Transcriptional regulator
KCTCHS21_RS01360	COG1132	(ABC) transporter
KCTCHS21_RS01370	COG1132	(ABC) transporter
KCTCHS21_RS01375	COG2814	Major facilitator Superfamily
KCTCHS21_RS01390	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS01395	COG4753	response regulator
KCTCHS21_RS01395	COG2207	Transcriptional regulator
KCTCHS21_RS01400	COG1653	transport
KCTCHS21_RS01405	COG4209	transmembrane transport
KCTCHS21_RS01410	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS01430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCTCHS21_RS01435	COG0488	(ABC) transporter
KCTCHS21_RS01450	COG1063	alcohol dehydrogenase
KCTCHS21_RS01460	COG0497	DNA recombination
KCTCHS21_RS01465	COG2197	response regulator
KCTCHS21_RS01485	COG1131	(ABC) transporter
KCTCHS21_RS01520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCTCHS21_RS01530	COG0667	Aldo Keto reductase
KCTCHS21_RS01565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS01570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS01575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS01605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KCTCHS21_RS01645	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS01655	COG3507	Belongs to the glycosyl hydrolase 43 family
KCTCHS21_RS01655	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS01655	COG2382	esterase
KCTCHS21_RS01670	COG0596	Alpha beta hydrolase
KCTCHS21_RS01675	COG0488	(ABC) transporter
KCTCHS21_RS01685	COG0604	alcohol dehydrogenase
KCTCHS21_RS01690	COG3620	sequence-specific DNA binding
KCTCHS21_RS01710	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS01715	COG1361	Conserved repeat domain
KCTCHS21_RS01720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KCTCHS21_RS01730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS01760	COG0697	spore germination
KCTCHS21_RS01775	COG2814	Major facilitator Superfamily
KCTCHS21_RS01785	COG1802	Transcriptional regulator
KCTCHS21_RS01800	COG5002	protein histidine kinase activity
KCTCHS21_RS01800	COG3447	MASE1 domain protein
KCTCHS21_RS01800	COG5001	Diguanylate cyclase
KCTCHS21_RS01820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS01825	COG0492	ferredoxin-NADP+ reductase activity
KCTCHS21_RS01855	COG3682	Transcriptional regulator
KCTCHS21_RS01860	COG0477	Major facilitator Superfamily
KCTCHS21_RS01875	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS01900	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS01945	COG4209	transmembrane transport
KCTCHS21_RS01950	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS01970	COG1063	alcohol dehydrogenase
KCTCHS21_RS01990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCTCHS21_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS02015	COG1846	Transcriptional regulator
KCTCHS21_RS02035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS02050	COG3226	Transcriptional regulator
KCTCHS21_RS02065	COG2972	Histidine kinase
KCTCHS21_RS02065	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS02070	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS02075	COG0708	Exodeoxyribonuclease III
KCTCHS21_RS02080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KCTCHS21_RS02085	COG1876	peptidase activity
KCTCHS21_RS02090	COG0561	phosphatase activity
KCTCHS21_RS02095	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS02110	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KCTCHS21_RS02130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCTCHS21_RS02135	COG5018	Exonuclease
KCTCHS21_RS02150	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS02160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCTCHS21_RS02185	COG3480	Lon protease (S16) C-terminal proteolytic domain
KCTCHS21_RS02190	COG3290	protein histidine kinase activity
KCTCHS21_RS02190	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS02210	COG0589	response to stress
KCTCHS21_RS02220	COG0488	(ABC) transporter
KCTCHS21_RS02235	COG2423	ornithine cyclodeaminase activity
KCTCHS21_RS02240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCTCHS21_RS02260	COG1120	ATPase activity
KCTCHS21_RS02265	COG0714	Associated with various cellular activities
KCTCHS21_RS02295	COG0791	NLP P60 protein
KCTCHS21_RS02295	COG1388	LysM domain
KCTCHS21_RS02310	COG3973	AAA domain
KCTCHS21_RS02325	COG1063	alcohol dehydrogenase
KCTCHS21_RS02330	COG1063	alcohol dehydrogenase
KCTCHS21_RS02340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCTCHS21_RS02345	COG0010	Belongs to the arginase family
KCTCHS21_RS02350	COG0018	arginyl-trna synthetase
KCTCHS21_RS02360	COG0018	arginyl-trna synthetase
KCTCHS21_RS02365	COG1404	Belongs to the peptidase S8 family
KCTCHS21_RS02370	COG3343	RNA polymerase activity
KCTCHS21_RS02375	COG0504	CTP synthase activity
KCTCHS21_RS02390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCTCHS21_RS02395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCTCHS21_RS02405	COG0254	rRNA binding
KCTCHS21_RS02420	COG3852	Histidine kinase
KCTCHS21_RS02425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCTCHS21_RS02430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCTCHS21_RS02435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCTCHS21_RS02505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCTCHS21_RS02510	COG2508	Transcriptional regulator
KCTCHS21_RS02515	COG3842	ATPase activity
KCTCHS21_RS02525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCTCHS21_RS02530	COG0546	phosphoglycolate phosphatase activity
KCTCHS21_RS02535	COG0110	maltose O-acetyltransferase activity
KCTCHS21_RS02540	COG1368	sulfuric ester hydrolase activity
KCTCHS21_RS02550	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCTCHS21_RS02555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCTCHS21_RS02560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCTCHS21_RS02565	COG0131	Imidazoleglycerol-phosphate dehydratase
KCTCHS21_RS02570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCTCHS21_RS02575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCTCHS21_RS02580	COG0107	imidazoleglycerol-phosphate synthase activity
KCTCHS21_RS02585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCTCHS21_RS02585	COG0140	phosphoribosyl-ATP diphosphatase activity
KCTCHS21_RS02590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCTCHS21_RS02610	COG1940	carbohydrate kinase activity
KCTCHS21_RS02615	COG1660	Displays ATPase and GTPase activities
KCTCHS21_RS02620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KCTCHS21_RS02625	COG1481	regulation of sporulation
KCTCHS21_RS02630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCTCHS21_RS02645	COG0740	serine-type endopeptidase activity
KCTCHS21_RS02665	COG0126	phosphoglycerate kinase activity
KCTCHS21_RS02680	COG0148	phosphopyruvate hydratase activity
KCTCHS21_RS02685	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS02690	COG0747	negative chemotaxis
KCTCHS21_RS02700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS02710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCTCHS21_RS02715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KCTCHS21_RS02725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KCTCHS21_RS02730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS02735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS02750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCTCHS21_RS02755	COG0557	exoribonuclease II activity
KCTCHS21_RS02760	COG0540	Belongs to the ATCase OTCase family
KCTCHS21_RS02765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCTCHS21_RS02805	COG1674	ftsk spoiiie
KCTCHS21_RS02840	COG0366	Alpha amylase catalytic
KCTCHS21_RS02845	COG0366	Alpha amylase catalytic
KCTCHS21_RS02850	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS02855	COG1175	transmembrane transport
KCTCHS21_RS02860	COG1653	transport
KCTCHS21_RS02890	COG2972	Histidine kinase
KCTCHS21_RS02895	COG4209	transmembrane transport
KCTCHS21_RS02900	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS02905	COG1653	transport
KCTCHS21_RS02935	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS02940	COG2972	Histidine kinase
KCTCHS21_RS02945	COG4753	response regulator
KCTCHS21_RS02945	COG2207	Transcriptional regulator
KCTCHS21_RS02950	COG1874	Beta-galactosidase
KCTCHS21_RS02955	COG1486	melibiose metabolic process
KCTCHS21_RS02960	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS02975	COG1361	Conserved repeat domain
KCTCHS21_RS02975	COG3266	domain, Protein
KCTCHS21_RS02975	COG2911	Protein conserved in bacteria
KCTCHS21_RS03010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS03015	COG2207	Transcriptional regulator
KCTCHS21_RS03015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS03040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCTCHS21_RS03045	COG0251	oxidation-reduction process
KCTCHS21_RS03060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCTCHS21_RS03070	COG1653	transport
KCTCHS21_RS03075	COG2207	Transcriptional regulator
KCTCHS21_RS03085	COG1175	transmembrane transport
KCTCHS21_RS03090	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS03100	COG2972	Histidine kinase
KCTCHS21_RS03115	COG1175	transmembrane transport
KCTCHS21_RS03120	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS03125	COG1501	Belongs to the glycosyl hydrolase 31 family
KCTCHS21_RS03135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCTCHS21_RS03140	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS03145	COG2972	Histidine kinase
KCTCHS21_RS03145	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS03165	COG1653	transport
KCTCHS21_RS03170	COG3012	SEC-C Motif Domain Protein
KCTCHS21_RS03190	COG5002	protein histidine kinase activity
KCTCHS21_RS03205	COG2911	Protein conserved in bacteria
KCTCHS21_RS03205	COG1361	Conserved repeat domain
KCTCHS21_RS03205	COG3266	domain, Protein
KCTCHS21_RS03210	COG3835	regulator
KCTCHS21_RS03220	COG0444	Belongs to the ABC transporter superfamily
KCTCHS21_RS03225	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS03230	COG0601	transmembrane transport
KCTCHS21_RS03240	COG4166	transmembrane transport
KCTCHS21_RS03245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCTCHS21_RS03265	COG1012	belongs to the aldehyde dehydrogenase family
KCTCHS21_RS03290	COG2972	Histidine kinase
KCTCHS21_RS03305	COG1175	transmembrane transport
KCTCHS21_RS03320	COG3266	domain, Protein
KCTCHS21_RS03320	COG1361	Conserved repeat domain
KCTCHS21_RS03320	COG2911	Protein conserved in bacteria
KCTCHS21_RS03335	COG1131	(ABC) transporter
KCTCHS21_RS03345	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS03350	COG2373	Large extracellular alpha-helical protein
KCTCHS21_RS03355	COG0604	alcohol dehydrogenase
KCTCHS21_RS03360	COG0640	Transcriptional regulator
KCTCHS21_RS03375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCTCHS21_RS03385	COG2972	Histidine kinase
KCTCHS21_RS03390	COG2207	Transcriptional regulator
KCTCHS21_RS03390	COG4753	response regulator
KCTCHS21_RS03400	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS03410	COG1940	carbohydrate kinase activity
KCTCHS21_RS03415	COG5002	protein histidine kinase activity
KCTCHS21_RS03420	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS03425	COG1361	Conserved repeat domain
KCTCHS21_RS03430	COG0584	glycerophosphoryl diester phosphodiesterase
KCTCHS21_RS03440	COG1929	Belongs to the glycerate kinase type-1 family
KCTCHS21_RS03480	COG3541	Predicted nucleotidyltransferase
KCTCHS21_RS03485	COG2205	protein histidine kinase activity
KCTCHS21_RS03490	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS03500	COG2207	Transcriptional regulator
KCTCHS21_RS03505	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KCTCHS21_RS03510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS03515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS03520	COG1609	Transcriptional regulator
KCTCHS21_RS03525	COG1653	transport
KCTCHS21_RS03530	COG1175	transmembrane transport
KCTCHS21_RS03535	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS03560	COG2814	Major facilitator Superfamily
KCTCHS21_RS03565	COG1309	transcriptional regulator
KCTCHS21_RS03580	COG1309	transcriptional regulator
KCTCHS21_RS03615	COG1361	Conserved repeat domain
KCTCHS21_RS03625	COG1061	Type III restriction enzyme res subunit
KCTCHS21_RS03630	COG0494	nUDIX hydrolase
KCTCHS21_RS03675	COG1396	sequence-specific DNA binding
KCTCHS21_RS03675	COG3800	Transcriptional regulator
KCTCHS21_RS03705	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS03725	COG0672	)-iron permease
KCTCHS21_RS03730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCTCHS21_RS03735	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS03740	COG5002	protein histidine kinase activity
KCTCHS21_RS03745	COG1840	ABC-type Fe3 transport system, periplasmic component
KCTCHS21_RS03750	COG1233	COG1233 Phytoene dehydrogenase and related
KCTCHS21_RS03765	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS03770	COG2124	cytochrome p450
KCTCHS21_RS03790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCTCHS21_RS03795	COG4715	Zinc finger, swim domain protein
KCTCHS21_RS03800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCTCHS21_RS03810	COG2271	Major facilitator Superfamily
KCTCHS21_RS03815	COG1994	Peptidase M50
KCTCHS21_RS03840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCTCHS21_RS03850	COG0601	transmembrane transport
KCTCHS21_RS03855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS03860	COG0444	Belongs to the ABC transporter superfamily
KCTCHS21_RS03865	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS03880	COG0024	Methionine aminopeptidase
KCTCHS21_RS03885	COG0328	RNA-DNA hybrid ribonuclease activity
KCTCHS21_RS03885	COG3341	Caulimovirus viroplasmin
KCTCHS21_RS03895	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS03900	COG1175	transmembrane transport
KCTCHS21_RS03905	COG1653	transport
KCTCHS21_RS03910	COG1361	Conserved repeat domain
KCTCHS21_RS03920	COG2188	Transcriptional regulator
KCTCHS21_RS03925	COG1486	melibiose metabolic process
KCTCHS21_RS03930	COG0363	glucosamine-6-phosphate deaminase activity
KCTCHS21_RS03940	COG0415	Belongs to the DNA photolyase family
KCTCHS21_RS03960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCTCHS21_RS03965	COG1132	(ABC) transporter
KCTCHS21_RS03970	COG1132	(ABC) transporter
KCTCHS21_RS03980	COG3963	phosphatidate phosphatase activity
KCTCHS21_RS04030	COG3384	dioxygenase
KCTCHS21_RS04040	COG4209	transmembrane transport
KCTCHS21_RS04045	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04055	COG4753	response regulator
KCTCHS21_RS04055	COG2207	Transcriptional regulator
KCTCHS21_RS04060	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS04065	COG1309	transcriptional regulator
KCTCHS21_RS04080	COG1486	melibiose metabolic process
KCTCHS21_RS04095	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS04105	COG3420	alginic acid biosynthetic process
KCTCHS21_RS04110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCTCHS21_RS04110	COG0551	DNA topoisomerase type I activity
KCTCHS21_RS04115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCTCHS21_RS04125	COG1278	Cold shock
KCTCHS21_RS04145	COG2814	Major facilitator Superfamily
KCTCHS21_RS04155	COG1368	sulfuric ester hydrolase activity
KCTCHS21_RS04170	COG0477	Major facilitator Superfamily
KCTCHS21_RS04185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCTCHS21_RS04190	COG1309	transcriptional regulator
KCTCHS21_RS04200	COG0667	Aldo Keto reductase
KCTCHS21_RS04235	COG2856	Zn peptidase
KCTCHS21_RS04285	COG1652	LysM domain
KCTCHS21_RS04305	COG3299	homolog of phage Mu protein gp47
KCTCHS21_RS04335	COG3409	Peptidoglycan-binding domain 1 protein
KCTCHS21_RS04345	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KCTCHS21_RS04350	COG1970	mechanosensitive ion channel activity
KCTCHS21_RS04355	COG4191	Histidine kinase
KCTCHS21_RS04360	COG1597	lipid kinase activity
KCTCHS21_RS04365	COG4335	DNA alkylation repair
KCTCHS21_RS04370	COG4129	membrane
KCTCHS21_RS04380	COG0398	Pfam SNARE associated Golgi protein
KCTCHS21_RS04385	COG2814	Major facilitator Superfamily
KCTCHS21_RS04395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCTCHS21_RS04420	COG0024	Methionine aminopeptidase
KCTCHS21_RS04430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCTCHS21_RS04430	COG2010	Cytochrome c
KCTCHS21_RS04450	COG3336	cytochrome c oxidase
KCTCHS21_RS04465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KCTCHS21_RS04480	COG3064	Membrane
KCTCHS21_RS04490	COG4753	response regulator
KCTCHS21_RS04490	COG2207	Transcriptional regulator
KCTCHS21_RS04495	COG2972	Histidine kinase
KCTCHS21_RS04500	COG4209	transmembrane transport
KCTCHS21_RS04505	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04550	COG1131	(ABC) transporter
KCTCHS21_RS04555	COG4152	abc transporter atp-binding protein
KCTCHS21_RS04560	COG1668	transmembrane transport
KCTCHS21_RS04565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCTCHS21_RS04580	COG2972	Histidine kinase
KCTCHS21_RS04590	COG1129	ABC transporter
KCTCHS21_RS04595	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCTCHS21_RS04600	COG1609	Transcriptional regulator
KCTCHS21_RS04610	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS04620	COG1070	Carbohydrate kinase
KCTCHS21_RS04630	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS04655	COG1063	alcohol dehydrogenase
KCTCHS21_RS04660	COG1063	alcohol dehydrogenase
KCTCHS21_RS04670	COG2755	lipolytic protein G-D-S-L family
KCTCHS21_RS04675	COG5566	PFAM Mor transcription activator
KCTCHS21_RS04680	COG1132	(ABC) transporter
KCTCHS21_RS04690	COG2207	Transcriptional regulator
KCTCHS21_RS04690	COG1917	Cupin 2, conserved barrel domain protein
KCTCHS21_RS04695	COG3345	alpha-galactosidase
KCTCHS21_RS04715	COG2972	Histidine kinase
KCTCHS21_RS04725	COG1653	transport
KCTCHS21_RS04735	COG1175	transmembrane transport
KCTCHS21_RS04740	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04755	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS04760	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS04770	COG1175	transmembrane transport
KCTCHS21_RS04775	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04800	COG1940	carbohydrate kinase activity
KCTCHS21_RS04820	COG2972	Histidine kinase
KCTCHS21_RS04825	COG4753	response regulator
KCTCHS21_RS04825	COG2207	Transcriptional regulator
KCTCHS21_RS04835	COG1175	transmembrane transport
KCTCHS21_RS04840	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04865	COG4977	sequence-specific DNA binding
KCTCHS21_RS04865	COG1917	Cupin 2, conserved barrel domain protein
KCTCHS21_RS04880	COG4753	response regulator
KCTCHS21_RS04880	COG2207	Transcriptional regulator
KCTCHS21_RS04885	COG2207	Transcriptional regulator
KCTCHS21_RS04885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS04895	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS04905	COG1175	transmembrane transport
KCTCHS21_RS04910	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS04940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCTCHS21_RS04965	COG0251	oxidation-reduction process
KCTCHS21_RS04975	COG3842	ATPase activity
KCTCHS21_RS04990	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05010	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05020	COG2207	Transcriptional regulator
KCTCHS21_RS05035	COG2207	Transcriptional regulator
KCTCHS21_RS05035	COG1917	Cupin 2, conserved barrel domain protein
KCTCHS21_RS05045	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS05050	COG2207	Transcriptional regulator
KCTCHS21_RS05050	COG4753	response regulator
KCTCHS21_RS05055	COG2972	Histidine kinase
KCTCHS21_RS05060	COG1653	transport
KCTCHS21_RS05070	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05085	COG2816	NAD+ diphosphatase activity
KCTCHS21_RS05110	COG0740	serine-type endopeptidase activity
KCTCHS21_RS05115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS05135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCTCHS21_RS05140	COG2873	o-acetylhomoserine
KCTCHS21_RS05145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCTCHS21_RS05160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS05165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS05170	COG1609	Transcriptional regulator
KCTCHS21_RS05180	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS05195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCTCHS21_RS05205	COG1486	melibiose metabolic process
KCTCHS21_RS05215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCTCHS21_RS05225	COG2197	response regulator
KCTCHS21_RS05235	COG0492	ferredoxin-NADP+ reductase activity
KCTCHS21_RS05250	COG2814	Major facilitator Superfamily
KCTCHS21_RS05255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCTCHS21_RS05285	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS05300	COG2223	nitrite transmembrane transporter activity
KCTCHS21_RS05310	COG0577	efflux transmembrane transporter activity
KCTCHS21_RS05315	COG1136	(ABC) transporter
KCTCHS21_RS05325	COG2514	catechol 2,3-dioxygenase activity
KCTCHS21_RS05340	COG1619	proteins homologs of microcin C7 resistance protein MccF
KCTCHS21_RS05345	COG0288	reversible hydration of carbon dioxide
KCTCHS21_RS05350	COG1704	LemA family
KCTCHS21_RS05360	COG2201	protein-glutamate methylesterase activity
KCTCHS21_RS05370	COG3250	beta-galactosidase activity
KCTCHS21_RS05380	COG2207	Transcriptional regulator
KCTCHS21_RS05385	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS05390	COG0383	alpha-mannosidase activity
KCTCHS21_RS05395	COG3507	Belongs to the glycosyl hydrolase 43 family
KCTCHS21_RS05405	COG4509	Sortase family
KCTCHS21_RS05410	COG4555	ABC transporter
KCTCHS21_RS05445	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS05455	COG3842	ATPase activity
KCTCHS21_RS05465	COG1175	transmembrane transport
KCTCHS21_RS05470	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05490	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05530	COG4209	transmembrane transport
KCTCHS21_RS05535	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05545	COG4948	Mandelate Racemase Muconate Lactonizing
KCTCHS21_RS05550	COG0492	ferredoxin-NADP+ reductase activity
KCTCHS21_RS05550	COG3118	belongs to the thioredoxin family
KCTCHS21_RS05560	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS05570	COG0598	Magnesium transport protein CorA
KCTCHS21_RS05575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCTCHS21_RS05590	COG1069	ribulokinase activity
KCTCHS21_RS05595	COG0398	Pfam SNARE associated Golgi protein
KCTCHS21_RS05615	COG1653	transport
KCTCHS21_RS05620	COG1175	transmembrane transport
KCTCHS21_RS05625	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS05630	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS05640	COG1501	Belongs to the glycosyl hydrolase 31 family
KCTCHS21_RS05655	COG0640	Transcriptional regulator
KCTCHS21_RS05665	COG1413	lyase activity
KCTCHS21_RS05670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCTCHS21_RS05675	COG0488	(ABC) transporter
KCTCHS21_RS05680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCTCHS21_RS05690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCTCHS21_RS05715	COG0067	glutamate synthase
KCTCHS21_RS05715	COG0070	glutamate synthase
KCTCHS21_RS05715	COG0069	glutamate synthase activity
KCTCHS21_RS05740	COG1396	sequence-specific DNA binding
KCTCHS21_RS05755	COG1131	(ABC) transporter
KCTCHS21_RS05760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KCTCHS21_RS05765	COG0489	protein tyrosine kinase activity
KCTCHS21_RS05770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCTCHS21_RS05775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KCTCHS21_RS05780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCTCHS21_RS05790	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS05795	COG0662	Cupin 2, conserved barrel domain protein
KCTCHS21_RS05795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KCTCHS21_RS05800	COG0297	glycogen (starch) synthase activity
KCTCHS21_RS05805	COG0110	maltose O-acetyltransferase activity
KCTCHS21_RS05810	COG4310	Domain of unknown function (DUF2172)
KCTCHS21_RS05825	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KCTCHS21_RS05835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCTCHS21_RS05840	COG1086	Polysaccharide biosynthesis protein
KCTCHS21_RS05845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCTCHS21_RS05855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCTCHS21_RS05860	COG2089	acid synthase
KCTCHS21_RS05865	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS05885	COG3944	biosynthesis protein
KCTCHS21_RS05900	COG0728	peptidoglycan biosynthetic process
KCTCHS21_RS05905	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS05930	COG1361	Conserved repeat domain
KCTCHS21_RS05930	COG3266	domain, Protein
KCTCHS21_RS05930	COG2911	Protein conserved in bacteria
KCTCHS21_RS05935	COG3944	biosynthesis protein
KCTCHS21_RS05940	COG0489	protein tyrosine kinase activity
KCTCHS21_RS05950	COG5039	Polysaccharide pyruvyl transferase
KCTCHS21_RS05965	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS05975	COG2244	polysaccharide biosynthetic process
KCTCHS21_RS05985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCTCHS21_RS05990	COG0297	glycogen (starch) synthase activity
KCTCHS21_RS06000	COG0739	heme binding
KCTCHS21_RS06005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCTCHS21_RS06015	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS06020	COG1793	dna ligase
KCTCHS21_RS06025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KCTCHS21_RS06040	COG0492	ferredoxin-NADP+ reductase activity
KCTCHS21_RS06060	COG2340	Cysteine-rich secretory protein family
KCTCHS21_RS06065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KCTCHS21_RS06070	COG0802	atpase or kinase
KCTCHS21_RS06075	COG1214	PFAM Peptidase M22, glycoprotease
KCTCHS21_RS06080	COG0456	acetyltransferase
KCTCHS21_RS06095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCTCHS21_RS06105	COG0488	(ABC) transporter
KCTCHS21_RS06110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCTCHS21_RS06115	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCTCHS21_RS06120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCTCHS21_RS06125	COG0805	protein transport
KCTCHS21_RS06130	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS06135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCTCHS21_RS06140	COG0459	protein refolding
KCTCHS21_RS06170	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS06175	COG2205	protein histidine kinase activity
KCTCHS21_RS06180	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS06185	COG0739	heme binding
KCTCHS21_RS06190	COG0436	Aminotransferase
KCTCHS21_RS06200	COG2972	Histidine kinase
KCTCHS21_RS06200	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS06220	COG1683	Conserved Protein
KCTCHS21_RS06245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCTCHS21_RS06250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KCTCHS21_RS06255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCTCHS21_RS06260	COG0864	Transcriptional regulator
KCTCHS21_RS06265	COG2337	Toxic component of a toxin-antitoxin (TA) module
KCTCHS21_RS06270	COG2309	aminopeptidase activity
KCTCHS21_RS06275	COG2183	response to ionizing radiation
KCTCHS21_RS06285	COG0778	Nitroreductase
KCTCHS21_RS06300	COG3091	SprT-like family
KCTCHS21_RS06310	COG1309	transcriptional regulator
KCTCHS21_RS06350	COG2986	histidine ammonia-lyase
KCTCHS21_RS06355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCTCHS21_RS06360	COG0765	amino acid transport
KCTCHS21_RS06365	COG1126	abc transporter atp-binding protein
KCTCHS21_RS06370	COG4209	transmembrane transport
KCTCHS21_RS06375	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06380	COG1653	transport
KCTCHS21_RS06420	COG1309	transcriptional regulator
KCTCHS21_RS06430	COG3180	Ammonia monooxygenase
KCTCHS21_RS06435	COG3961	Belongs to the TPP enzyme family
KCTCHS21_RS06450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KCTCHS21_RS06480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCTCHS21_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS06510	COG4948	Mandelate Racemase Muconate Lactonizing
KCTCHS21_RS06525	COG4209	transmembrane transport
KCTCHS21_RS06530	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06545	COG2972	Histidine kinase
KCTCHS21_RS06550	COG2207	Transcriptional regulator
KCTCHS21_RS06550	COG4753	response regulator
KCTCHS21_RS06575	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS06595	COG1796	DNA polymerase
KCTCHS21_RS06595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCTCHS21_RS06600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCTCHS21_RS06600	COG1796	DNA polymerase
KCTCHS21_RS06610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCTCHS21_RS06610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCTCHS21_RS06630	COG1175	transmembrane transport
KCTCHS21_RS06635	COG3833	ABC-type maltose transport systems, permease component
KCTCHS21_RS06640	COG3842	ATPase activity
KCTCHS21_RS06645	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS06650	COG1609	Transcriptional regulator
KCTCHS21_RS06655	COG1653	transport
KCTCHS21_RS06660	COG1175	transmembrane transport
KCTCHS21_RS06665	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06690	COG1361	Conserved repeat domain
KCTCHS21_RS06700	COG2207	Transcriptional regulator
KCTCHS21_RS06725	COG2972	Histidine kinase
KCTCHS21_RS06730	COG2207	Transcriptional regulator
KCTCHS21_RS06730	COG4753	response regulator
KCTCHS21_RS06735	COG1653	transport
KCTCHS21_RS06745	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06755	COG3250	beta-galactosidase activity
KCTCHS21_RS06760	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
KCTCHS21_RS06765	COG2755	lipolytic protein G-D-S-L family
KCTCHS21_RS06765	COG0657	acetylesterase activity
KCTCHS21_RS06775	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS06795	COG1609	Transcriptional regulator
KCTCHS21_RS06800	COG1609	Transcriptional regulator
KCTCHS21_RS06815	COG1175	transmembrane transport
KCTCHS21_RS06820	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06825	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS06830	COG2207	Transcriptional regulator
KCTCHS21_RS06845	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06870	COG3594	Acyltransferase
KCTCHS21_RS06890	COG4209	transmembrane transport
KCTCHS21_RS06895	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS06905	COG4753	response regulator
KCTCHS21_RS06905	COG4753	response regulator
KCTCHS21_RS06905	COG2207	Transcriptional regulator
KCTCHS21_RS06905	COG2207	Transcriptional regulator
KCTCHS21_RS06910	COG2972	Histidine kinase
KCTCHS21_RS06920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS06940	COG3103	Sh3 type 3 domain protein
KCTCHS21_RS06940	COG0791	NLP P60 protein
KCTCHS21_RS06940	COG1388	LysM domain
KCTCHS21_RS06950	COG0194	GDP metabolic process
KCTCHS21_RS06960	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS06985	COG1396	sequence-specific DNA binding
KCTCHS21_RS07080	COG4974	Belongs to the 'phage' integrase family
KCTCHS21_RS07085	COG5484	DNA packaging
KCTCHS21_RS07105	COG2369	cell adhesion
KCTCHS21_RS07190	COG4193	domain, Protein
KCTCHS21_RS07205	COG3299	homolog of phage Mu protein gp47
KCTCHS21_RS07240	COG3409	Peptidoglycan-binding domain 1 protein
KCTCHS21_RS07245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCTCHS21_RS07310	COG1090	epimerase
KCTCHS21_RS07330	COG0788	formyltetrahydrofolate deformylase activity
KCTCHS21_RS07340	COG3123	guanosine phosphorylase activity
KCTCHS21_RS07360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS07365	COG4464	protein tyrosine phosphatase activity
KCTCHS21_RS07375	COG0489	protein tyrosine kinase activity
KCTCHS21_RS07380	COG1086	Polysaccharide biosynthesis protein
KCTCHS21_RS07390	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS07405	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS07405	COG0297	glycogen (starch) synthase activity
KCTCHS21_RS07415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KCTCHS21_RS07425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCTCHS21_RS07430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCTCHS21_RS07435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCTCHS21_RS07450	COG1739	Uncharacterized protein family UPF0029
KCTCHS21_RS07455	COG0432	Pfam Uncharacterised protein family UPF0047
KCTCHS21_RS07460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KCTCHS21_RS07465	COG4208	sulfate ABC transporter
KCTCHS21_RS07470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KCTCHS21_RS07475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCTCHS21_RS07520	COG0667	Aldo Keto reductase
KCTCHS21_RS07525	COG3458	cephalosporin-C deacetylase activity
KCTCHS21_RS07535	COG1482	cell wall glycoprotein biosynthetic process
KCTCHS21_RS07540	COG0346	lactoylglutathione lyase activity
KCTCHS21_RS07550	COG1242	4 iron, 4 sulfur cluster binding
KCTCHS21_RS07560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS07585	COG1215	transferase activity, transferring glycosyl groups
KCTCHS21_RS07590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCTCHS21_RS07595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KCTCHS21_RS07600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCTCHS21_RS07625	COG0028	Belongs to the TPP enzyme family
KCTCHS21_RS07630	COG0440	acetolactate synthase activity
KCTCHS21_RS07635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCTCHS21_RS07640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCTCHS21_RS07645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCTCHS21_RS07650	COG1940	carbohydrate kinase activity
KCTCHS21_RS07665	COG1175	transmembrane transport
KCTCHS21_RS07670	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KCTCHS21_RS07675	COG1063	alcohol dehydrogenase
KCTCHS21_RS07680	COG1012	belongs to the aldehyde dehydrogenase family
KCTCHS21_RS07695	COG0473	3-isopropylmalate dehydrogenase activity
KCTCHS21_RS07700	COG0450	alkyl hydroperoxide reductase
KCTCHS21_RS07710	COG1191	sigma factor activity
KCTCHS21_RS07720	COG3852	Histidine kinase
KCTCHS21_RS07725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCTCHS21_RS07745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCTCHS21_RS07760	COG2409	Drug exporters of the RND superfamily
KCTCHS21_RS07760	COG1033	growth of symbiont in host cell
KCTCHS21_RS07770	COG1984	allophanate hydrolase subunit 2
KCTCHS21_RS07775	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KCTCHS21_RS07790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCTCHS21_RS07795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCTCHS21_RS07800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCTCHS21_RS07810	COG4585	Histidine kinase
KCTCHS21_RS07815	COG2197	response regulator
KCTCHS21_RS07820	COG4549	nuclear export factor GLE1
KCTCHS21_RS07825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCTCHS21_RS07835	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCTCHS21_RS07850	COG1193	negative regulation of DNA recombination
KCTCHS21_RS07855	COG3766	membrane
KCTCHS21_RS07880	COG1522	sequence-specific DNA binding
KCTCHS21_RS07885	COG0436	Aminotransferase
KCTCHS21_RS07900	COG2096	Adenosyltransferase
KCTCHS21_RS07905	COG0564	pseudouridine synthase activity
KCTCHS21_RS07910	COG1393	Belongs to the ArsC family
KCTCHS21_RS07915	COG0436	Aminotransferase
KCTCHS21_RS07920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCTCHS21_RS07935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS07960	COG2368	4-hydroxyphenylacetate
KCTCHS21_RS07965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS07970	COG1904	glucuronate isomerase
KCTCHS21_RS07995	COG0598	Magnesium transport protein CorA
KCTCHS21_RS08000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KCTCHS21_RS08005	COG0626	cystathionine gamma-synthase activity
KCTCHS21_RS08010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KCTCHS21_RS08015	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KCTCHS21_RS08030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCTCHS21_RS08035	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS08050	COG4585	Histidine kinase
KCTCHS21_RS08055	COG2197	response regulator
KCTCHS21_RS08065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCTCHS21_RS08075	COG5002	protein histidine kinase activity
KCTCHS21_RS08075	COG3850	Histidine kinase
KCTCHS21_RS08080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCTCHS21_RS08090	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KCTCHS21_RS08095	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KCTCHS21_RS08100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KCTCHS21_RS08105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KCTCHS21_RS08115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KCTCHS21_RS08130	COG2002	toxin-antitoxin pair type II binding
KCTCHS21_RS08150	COG2766	serine protein kinase
KCTCHS21_RS08170	COG4512	PFAM Accessory gene regulator B
KCTCHS21_RS08185	COG2226	methyltransferase
KCTCHS21_RS08190	COG0534	Mate efflux family protein
KCTCHS21_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS08220	COG1196	nuclear chromosome segregation
KCTCHS21_RS08230	COG2719	SpoVR family
KCTCHS21_RS08245	COG3973	AAA domain
KCTCHS21_RS08250	COG0514	ATP-dependent DNA helicase (RecQ)
KCTCHS21_RS08265	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS08270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCTCHS21_RS08275	COG1285	pathogenesis
KCTCHS21_RS08285	COG0659	secondary active sulfate transmembrane transporter activity
KCTCHS21_RS08295	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS08300	COG0431	NADPH-dependent FMN reductase
KCTCHS21_RS08305	COG1126	abc transporter atp-binding protein
KCTCHS21_RS08310	COG1473	amidohydrolase
KCTCHS21_RS08330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS08340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KCTCHS21_RS08345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCTCHS21_RS08350	COG0183	Belongs to the thiolase family
KCTCHS21_RS08355	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCTCHS21_RS08360	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS08365	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS08370	COG5002	protein histidine kinase activity
KCTCHS21_RS08370	COG3850	Histidine kinase
KCTCHS21_RS08380	COG0531	amino acid
KCTCHS21_RS08385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCTCHS21_RS08400	COG0823	Involved in the tonB-independent uptake of proteins
KCTCHS21_RS08400	COG4946	Tricorn protease homolog
KCTCHS21_RS08400	COG1506	peptidase
KCTCHS21_RS08410	COG2814	Major facilitator Superfamily
KCTCHS21_RS08420	COG2718	Belongs to the UPF0229 family
KCTCHS21_RS08430	COG0420	3'-5' exonuclease activity
KCTCHS21_RS08435	COG0419	ATPase involved in DNA repair
KCTCHS21_RS08455	COG3437	response regulator, receiver
KCTCHS21_RS08455	COG2770	Histidine kinase
KCTCHS21_RS08465	COG2363	Small membrane protein
KCTCHS21_RS08480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCTCHS21_RS08485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCTCHS21_RS08500	COG3377	Domain of unknown function (DUF1805)
KCTCHS21_RS08525	COG0396	ATPase activity
KCTCHS21_RS08530	COG0719	Fe-S assembly protein
KCTCHS21_RS08535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCTCHS21_RS08540	COG0822	iron-sulfur transferase activity
KCTCHS21_RS08545	COG0719	Fe-S assembly protein
KCTCHS21_RS08585	COG2002	toxin-antitoxin pair type II binding
KCTCHS21_RS08625	COG1061	Type III restriction enzyme res subunit
KCTCHS21_RS08815	COG0791	NLP P60 protein
KCTCHS21_RS08830	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS08845	COG1105	Belongs to the carbohydrate kinase PfkB family
KCTCHS21_RS08850	COG0737	Belongs to the 5'-nucleotidase family
KCTCHS21_RS08865	COG0535	radical SAM domain protein
KCTCHS21_RS08870	COG1253	flavin adenine dinucleotide binding
KCTCHS21_RS08900	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KCTCHS21_RS08905	COG4521	taurine ABC transporter
KCTCHS21_RS08910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS08930	COG3546	catalase activity
KCTCHS21_RS08940	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS08950	COG2268	Band 7 protein
KCTCHS21_RS08960	COG0671	phosphoesterase, PA-phosphatase related
KCTCHS21_RS08975	COG0297	glycogen (starch) synthase activity
KCTCHS21_RS09000	COG0189	ligase activity
KCTCHS21_RS09010	COG0189	ligase activity
KCTCHS21_RS09015	COG2226	methyltransferase
KCTCHS21_RS09040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KCTCHS21_RS09045	COG5401	PFAM Sporulation and spore germination
KCTCHS21_RS09060	COG0697	spore germination
KCTCHS21_RS09065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCTCHS21_RS09070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCTCHS21_RS09075	COG0367	asparagine synthase
KCTCHS21_RS09115	COG1396	sequence-specific DNA binding
KCTCHS21_RS09145	COG1846	Transcriptional regulator
KCTCHS21_RS09235	COG0582	viral genome integration into host DNA
KCTCHS21_RS09335	COG3299	homolog of phage Mu protein gp47
KCTCHS21_RS09345	COG5301	cellulose 1,4-beta-cellobiosidase activity
KCTCHS21_RS09390	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCTCHS21_RS09395	COG0740	serine-type endopeptidase activity
KCTCHS21_RS09400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCTCHS21_RS09415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCTCHS21_RS09425	COG0470	DNA polymerase III
KCTCHS21_RS09425	COG1067	ATP-dependent peptidase activity
KCTCHS21_RS09435	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KCTCHS21_RS09450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCTCHS21_RS09450	COG1648	precorrin-2 dehydrogenase activity
KCTCHS21_RS09455	COG0181	hydroxymethylbilane synthase activity
KCTCHS21_RS09465	COG0113	porphobilinogen synthase activity
KCTCHS21_RS09470	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCTCHS21_RS09475	COG1388	LysM domain
KCTCHS21_RS09495	COG0525	valine-tRNA ligase activity
KCTCHS21_RS09500	COG0285	dihydrofolate synthase activity
KCTCHS21_RS09505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCTCHS21_RS09520	COG0424	maF-like protein
KCTCHS21_RS09525	COG2003	Belongs to the UPF0758 family
KCTCHS21_RS09530	COG1077	Cell shape determining protein MreB Mrl
KCTCHS21_RS09545	COG0850	regulation of cytokinetic process
KCTCHS21_RS09550	COG2894	cell division
KCTCHS21_RS09555	COG0772	Belongs to the SEDS family
KCTCHS21_RS09565	COG1994	Peptidase M50
KCTCHS21_RS09570	COG1530	ribonuclease E activity
KCTCHS21_RS09575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KCTCHS21_RS09580	COG2868	ribosomal protein
KCTCHS21_RS09595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCTCHS21_RS09600	COG4492	Belongs to the UPF0735 family
KCTCHS21_RS09605	COG0460	homoserine dehydrogenase
KCTCHS21_RS09610	COG0083	homoserine kinase activity
KCTCHS21_RS09615	COG0077	Prephenate dehydratase
KCTCHS21_RS09620	COG1388	LysM domain
KCTCHS21_RS09630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KCTCHS21_RS09635	COG0632	four-way junction helicase activity
KCTCHS21_RS09640	COG2255	four-way junction helicase activity
KCTCHS21_RS09650	COG2385	sporulation resulting in formation of a cellular spore
KCTCHS21_RS09650	COG2385	sporulation resulting in formation of a cellular spore
KCTCHS21_RS09655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCTCHS21_RS09665	COG1862	Preprotein translocase
KCTCHS21_RS09670	COG0671	phosphoesterase, PA-phosphatase related
KCTCHS21_RS09680	COG2323	membrane
KCTCHS21_RS09685	COG2244	polysaccharide biosynthetic process
KCTCHS21_RS09695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCTCHS21_RS09695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCTCHS21_RS09700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCTCHS21_RS09705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCTCHS21_RS09710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KCTCHS21_RS09710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KCTCHS21_RS09715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCTCHS21_RS09720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCTCHS21_RS09725	COG1490	D-aminoacyl-tRNA deacylase activity
KCTCHS21_RS09740	COG0124	histidyl-tRNA synthetase
KCTCHS21_RS09745	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KCTCHS21_RS09750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCTCHS21_RS09775	COG5337	Spore coat protein CotH
KCTCHS21_RS09780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCTCHS21_RS09785	COG1253	flavin adenine dinucleotide binding
KCTCHS21_RS09815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCTCHS21_RS09830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS09835	COG0513	Belongs to the DEAD box helicase family
KCTCHS21_RS09840	COG5578	integral membrane protein
KCTCHS21_RS09855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCTCHS21_RS09860	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS09865	COG2738	Putative neutral zinc metallopeptidase
KCTCHS21_RS09870	COG0789	Transcriptional regulator
KCTCHS21_RS09875	COG0004	ammonium transporteR
KCTCHS21_RS09885	COG2176	DNA-directed DNA polymerase activity
KCTCHS21_RS09890	COG2814	Major facilitator Superfamily
KCTCHS21_RS09900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCTCHS21_RS09905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCTCHS21_RS09910	COG1141	Ferredoxin
KCTCHS21_RS09930	COG1376	ErfK ybiS ycfS ynhG family protein
KCTCHS21_RS09935	COG0167	dihydroorotate dehydrogenase activity
KCTCHS21_RS09940	COG2357	RelA SpoT domain protein
KCTCHS21_RS09955	COG1187	pseudouridine synthase activity
KCTCHS21_RS09960	COG0561	phosphatase activity
KCTCHS21_RS09975	COG5001	Diguanylate cyclase
KCTCHS21_RS09980	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS09985	COG0420	3'-5' exonuclease activity
KCTCHS21_RS09990	COG4717	serine-type aminopeptidase activity
KCTCHS21_RS09995	COG3949	Membrane
KCTCHS21_RS10005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCTCHS21_RS10020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCTCHS21_RS10040	COG5002	protein histidine kinase activity
KCTCHS21_RS10040	COG3850	Histidine kinase
KCTCHS21_RS10045	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS10050	COG1175	transmembrane transport
KCTCHS21_RS10080	COG2205	protein histidine kinase activity
KCTCHS21_RS10085	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS10090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCTCHS21_RS10095	COG0393	Putative heavy-metal-binding
KCTCHS21_RS10100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCTCHS21_RS10125	COG4209	transmembrane transport
KCTCHS21_RS10130	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10165	COG5492	domain, Protein
KCTCHS21_RS10200	COG5492	domain, Protein
KCTCHS21_RS10220	COG1653	transport
KCTCHS21_RS10225	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10230	COG4209	transmembrane transport
KCTCHS21_RS10240	COG2972	Histidine kinase
KCTCHS21_RS10245	COG2207	Transcriptional regulator
KCTCHS21_RS10245	COG4753	response regulator
KCTCHS21_RS10260	COG0457	Tetratricopeptide repeat
KCTCHS21_RS10270	COG1361	Conserved repeat domain
KCTCHS21_RS10275	COG1361	Conserved repeat domain
KCTCHS21_RS10310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCTCHS21_RS10340	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS10345	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS10345	COG0457	Tetratricopeptide repeat
KCTCHS21_RS10355	COG1216	Glycosyl transferase, family 2
KCTCHS21_RS10380	COG1216	Glycosyl transferase, family 2
KCTCHS21_RS10385	COG0457	Tetratricopeptide repeat
KCTCHS21_RS10385	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS10390	COG2207	Transcriptional regulator
KCTCHS21_RS10395	COG4209	transmembrane transport
KCTCHS21_RS10400	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10405	COG1653	transport
KCTCHS21_RS10415	COG3507	Belongs to the glycosyl hydrolase 43 family
KCTCHS21_RS10435	COG0025	NhaP-type Na H and K H
KCTCHS21_RS10445	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS10450	COG5002	protein histidine kinase activity
KCTCHS21_RS10475	COG4209	transmembrane transport
KCTCHS21_RS10480	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10490	COG2972	Histidine kinase
KCTCHS21_RS10495	COG4753	response regulator
KCTCHS21_RS10495	COG2207	Transcriptional regulator
KCTCHS21_RS10500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCTCHS21_RS10500	COG4191	Histidine kinase
KCTCHS21_RS10505	COG2207	Transcriptional regulator
KCTCHS21_RS10505	COG4753	response regulator
KCTCHS21_RS10510	COG1653	transport
KCTCHS21_RS10515	COG4209	transmembrane transport
KCTCHS21_RS10520	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10540	COG3345	alpha-galactosidase
KCTCHS21_RS10550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCTCHS21_RS10555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS10560	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS10565	COG2814	Major facilitator Superfamily
KCTCHS21_RS10570	COG1280	lysine exporter protein (LysE YggA)
KCTCHS21_RS10575	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS10580	COG2201	protein-glutamate methylesterase activity
KCTCHS21_RS10585	COG2207	Transcriptional regulator
KCTCHS21_RS10595	COG1175	transmembrane transport
KCTCHS21_RS10600	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCTCHS21_RS10620	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS10625	COG1802	Transcriptional regulator
KCTCHS21_RS10635	COG1609	Transcriptional regulator
KCTCHS21_RS10640	COG0383	alpha-mannosidase activity
KCTCHS21_RS10655	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10685	COG2207	Transcriptional regulator
KCTCHS21_RS10690	COG1414	Transcriptional regulator
KCTCHS21_RS10700	COG4209	transmembrane transport
KCTCHS21_RS10705	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10710	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS10730	COG0789	Transcriptional regulator
KCTCHS21_RS10730	COG4978	Transcriptional regulator
KCTCHS21_RS10735	COG1414	Transcriptional regulator
KCTCHS21_RS10745	COG3665	Urea carboxylase-associated protein
KCTCHS21_RS10750	COG0439	Biotin carboxylase
KCTCHS21_RS10770	COG0004	ammonium transporteR
KCTCHS21_RS10785	COG1414	Transcriptional regulator
KCTCHS21_RS10795	COG0640	Transcriptional regulator
KCTCHS21_RS10800	COG0656	L-ascorbic acid biosynthetic process
KCTCHS21_RS10805	COG4209	transmembrane transport
KCTCHS21_RS10810	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS10825	COG2207	Transcriptional regulator
KCTCHS21_RS10825	COG4753	response regulator
KCTCHS21_RS10835	COG2814	Major facilitator Superfamily
KCTCHS21_RS10865	COG3794	PFAM blue (type 1) copper domain protein
KCTCHS21_RS10870	COG1971	Probably functions as a manganese efflux pump
KCTCHS21_RS10880	COG1309	transcriptional regulator
KCTCHS21_RS10885	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS10890	COG2249	NAD(P)H dehydrogenase (quinone) activity
KCTCHS21_RS10895	COG1999	signal sequence binding
KCTCHS21_RS10900	COG2010	Cytochrome c
KCTCHS21_RS10905	COG1271	oxidase subunit
KCTCHS21_RS10910	COG1294	oxidase, subunit
KCTCHS21_RS10915	COG4988	ABC transporter
KCTCHS21_RS10920	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCTCHS21_RS10940	COG0477	Major facilitator Superfamily
KCTCHS21_RS10945	COG2807	transmembrane transport
KCTCHS21_RS10950	COG5002	protein histidine kinase activity
KCTCHS21_RS10995	COG4209	transmembrane transport
KCTCHS21_RS11000	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS11020	COG2188	Transcriptional regulator
KCTCHS21_RS11025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KCTCHS21_RS11030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS11040	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS11055	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS11060	COG1063	alcohol dehydrogenase
KCTCHS21_RS11070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCTCHS21_RS11080	COG2140	Oxalate decarboxylase
KCTCHS21_RS11085	COG0667	Aldo Keto reductase
KCTCHS21_RS11120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCTCHS21_RS11130	COG1876	peptidase activity
KCTCHS21_RS11140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS11145	COG0800	Aldolase
KCTCHS21_RS11155	COG0574	Belongs to the PEP-utilizing enzyme family
KCTCHS21_RS11155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCTCHS21_RS11160	COG0517	IMP dehydrogenase activity
KCTCHS21_RS11165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCTCHS21_RS11170	COG1414	Transcriptional regulator
KCTCHS21_RS11175	COG0129	dihydroxy-acid dehydratase activity
KCTCHS21_RS11180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCTCHS21_RS11190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCTCHS21_RS11205	COG1653	transport
KCTCHS21_RS11210	COG4209	transmembrane transport
KCTCHS21_RS11215	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS11225	COG4753	response regulator
KCTCHS21_RS11225	COG2207	Transcriptional regulator
KCTCHS21_RS11235	COG1361	Conserved repeat domain
KCTCHS21_RS11240	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS11245	COG2207	Transcriptional regulator
KCTCHS21_RS11245	COG4753	response regulator
KCTCHS21_RS11260	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KCTCHS21_RS11290	COG4209	transmembrane transport
KCTCHS21_RS11295	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS11345	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS11350	COG2186	Transcriptional regulator
KCTCHS21_RS11355	COG0277	FAD linked oxidase domain protein
KCTCHS21_RS11360	COG0247	lactate metabolic process
KCTCHS21_RS11365	COG0735	belongs to the Fur family
KCTCHS21_RS11375	COG5285	phytanoyl-CoA dioxygenase
KCTCHS21_RS11380	COG0662	Cupin 2, conserved barrel domain protein
KCTCHS21_RS11380	COG2207	Transcriptional regulator
KCTCHS21_RS11400	COG2861	carbohydrate metabolic process
KCTCHS21_RS11405	COG2247	cell wall binding repeat
KCTCHS21_RS11405	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS11425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCTCHS21_RS11445	COG0210	DNA helicase
KCTCHS21_RS11470	COG1764	response to oxidative stress
KCTCHS21_RS11475	COG1309	transcriptional regulator
KCTCHS21_RS11490	COG2814	Major facilitator Superfamily
KCTCHS21_RS11510	COG1175	transmembrane transport
KCTCHS21_RS11515	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS11525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS11540	COG0667	Aldo Keto reductase
KCTCHS21_RS11555	COG3962	Belongs to the TPP enzyme family
KCTCHS21_RS11560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS11565	COG1012	belongs to the aldehyde dehydrogenase family
KCTCHS21_RS11575	COG3718	enzyme involved in inositol metabolism
KCTCHS21_RS11580	COG0442	prolyl-tRNA aminoacylation
KCTCHS21_RS11595	COG2188	Transcriptional regulator
KCTCHS21_RS11600	COG1802	Transcriptional regulator
KCTCHS21_RS11605	COG4948	Mandelate Racemase Muconate Lactonizing
KCTCHS21_RS11620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS11620	COG2207	Transcriptional regulator
KCTCHS21_RS11625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS11630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS11635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS11640	COG1132	(ABC) transporter
KCTCHS21_RS11655	COG0672	)-iron permease
KCTCHS21_RS11660	COG2822	iron ion transport
KCTCHS21_RS11665	COG2837	iron assimilation
KCTCHS21_RS11670	COG1408	metallophosphoesterase
KCTCHS21_RS11675	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS11680	COG1335	isochorismatase
KCTCHS21_RS11685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCTCHS21_RS11690	COG1307	EDD domain protein, DegV family
KCTCHS21_RS11705	COG0477	Major facilitator Superfamily
KCTCHS21_RS11715	COG2207	Transcriptional regulator
KCTCHS21_RS11715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS11720	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS11725	COG1435	thymidine kinase activity
KCTCHS21_RS11740	COG0784	Response regulator, receiver
KCTCHS21_RS11740	COG2205	protein histidine kinase activity
KCTCHS21_RS11745	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS11750	COG5522	Integral membrane protein (intg_mem_TP0381)
KCTCHS21_RS11755	COG2116	formate transmembrane transporter activity
KCTCHS21_RS11760	COG0039	L-malate dehydrogenase activity
KCTCHS21_RS11775	COG0679	Auxin Efflux Carrier
KCTCHS21_RS11795	COG2207	Transcriptional regulator
KCTCHS21_RS11800	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS11805	COG1312	Catalyzes the dehydration of D-mannonate
KCTCHS21_RS11810	COG0800	Aldolase
KCTCHS21_RS11820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCTCHS21_RS11825	COG0517	IMP dehydrogenase activity
KCTCHS21_RS11830	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCTCHS21_RS11840	COG4175	Glycine betaine
KCTCHS21_RS11840	COG0517	IMP dehydrogenase activity
KCTCHS21_RS11850	COG0564	pseudouridine synthase activity
KCTCHS21_RS11855	COG2814	Major facilitator Superfamily
KCTCHS21_RS11865	COG1132	(ABC) transporter
KCTCHS21_RS11870	COG0778	Nitroreductase
KCTCHS21_RS11885	COG1609	Transcriptional regulator
KCTCHS21_RS11890	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
KCTCHS21_RS11900	COG1070	Carbohydrate kinase
KCTCHS21_RS11905	COG4154	Belongs to the RbsD FucU family
KCTCHS21_RS11910	COG2378	regulation of single-species biofilm formation
KCTCHS21_RS11915	COG3708	Transcriptional regulator
KCTCHS21_RS11925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS11965	COG2160	L-arabinose isomerase activity
KCTCHS21_RS11970	COG0628	permease
KCTCHS21_RS11975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCTCHS21_RS11980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCTCHS21_RS11985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCTCHS21_RS11990	COG0297	glycogen (starch) synthase activity
KCTCHS21_RS12010	COG2508	Transcriptional regulator
KCTCHS21_RS12060	COG0735	belongs to the Fur family
KCTCHS21_RS12065	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KCTCHS21_RS12070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCTCHS21_RS12070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCTCHS21_RS12080	COG3443	Belongs to the bacterial solute-binding protein 9 family
KCTCHS21_RS12080	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCTCHS21_RS12085	COG1121	(ABC) transporter
KCTCHS21_RS12090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCTCHS21_RS12095	COG0785	Cytochrome C biogenesis protein
KCTCHS21_RS12100	COG1533	DNA photolyase activity
KCTCHS21_RS12110	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCTCHS21_RS12120	COG3872	metal-dependent enzyme
KCTCHS21_RS12130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCTCHS21_RS12135	COG0006	proline dipeptidase activity
KCTCHS21_RS12140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCTCHS21_RS12150	COG2707	UPF0756 membrane protein
KCTCHS21_RS12155	COG1809	phosphosulfolactate synthase activity
KCTCHS21_RS12165	COG3854	ATPases associated with a variety of cellular activities
KCTCHS21_RS12205	COG0511	ligase activity, forming carbon-carbon bonds
KCTCHS21_RS12210	COG0439	Biotin carboxylase
KCTCHS21_RS12215	COG1302	Protein conserved in bacteria
KCTCHS21_RS12230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCTCHS21_RS12235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCTCHS21_RS12240	COG1570	exodeoxyribonuclease VII activity
KCTCHS21_RS12255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCTCHS21_RS12260	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KCTCHS21_RS12270	COG1438	arginine binding
KCTCHS21_RS12275	COG0497	DNA recombination
KCTCHS21_RS12280	COG0750	zinc metalloprotease
KCTCHS21_RS12285	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS12335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCTCHS21_RS12340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KCTCHS21_RS12345	COG0022	dehydrogenase e1 component
KCTCHS21_RS12350	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCTCHS21_RS12355	COG0321	lipoyl(octanoyl) transferase activity
KCTCHS21_RS12360	COG2195	Cleaves the N-terminal amino acid of tripeptides
KCTCHS21_RS12375	COG1379	DNA repair
KCTCHS21_RS12380	COG1300	Membrane
KCTCHS21_RS12385	COG0735	belongs to the Fur family
KCTCHS21_RS12390	COG0386	Belongs to the glutathione peroxidase family
KCTCHS21_RS12395	COG1846	Transcriptional regulator
KCTCHS21_RS12400	COG0386	Belongs to the glutathione peroxidase family
KCTCHS21_RS12405	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS12415	COG0686	Belongs to the AlaDH PNT family
KCTCHS21_RS12430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCTCHS21_RS12455	COG0726	polysaccharide deacetylase
KCTCHS21_RS12480	COG1686	Belongs to the peptidase S11 family
KCTCHS21_RS12485	COG1366	Belongs to the anti-sigma-factor antagonist family
KCTCHS21_RS12490	COG2172	sigma factor antagonist activity
KCTCHS21_RS12510	COG0697	spore germination
KCTCHS21_RS12515	COG0019	diaminopimelate decarboxylase activity
KCTCHS21_RS12520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCTCHS21_RS12525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCTCHS21_RS12525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCTCHS21_RS12530	COG0307	riboflavin synthase, alpha
KCTCHS21_RS12535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCTCHS21_RS12535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCTCHS21_RS12540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCTCHS21_RS12545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCTCHS21_RS12550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCTCHS21_RS12560	COG3874	Sporulation protein YtfJ
KCTCHS21_RS12565	COG1686	Belongs to the peptidase S11 family
KCTCHS21_RS12570	COG2715	membrane protein required for spore maturation
KCTCHS21_RS12575	COG0700	Nucleoside recognition
KCTCHS21_RS12585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCTCHS21_RS12590	COG1333	cytochrome c biogenesis protein
KCTCHS21_RS12595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KCTCHS21_RS12600	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS12605	COG5002	protein histidine kinase activity
KCTCHS21_RS12605	COG5002	protein histidine kinase activity
KCTCHS21_RS12610	COG0477	Major facilitator Superfamily
KCTCHS21_RS12620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCTCHS21_RS12630	COG1266	CAAX protease self-immunity
KCTCHS21_RS12640	COG0726	polysaccharide deacetylase
KCTCHS21_RS12650	COG4862	establishment of competence for transformation
KCTCHS21_RS12655	COG2339	peptidase activity
KCTCHS21_RS12660	COG2959	enzyme of heme biosynthesis
KCTCHS21_RS12675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCTCHS21_RS12705	COG1160	GTP binding
KCTCHS21_RS12710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KCTCHS21_RS12715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KCTCHS21_RS12750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCTCHS21_RS12785	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KCTCHS21_RS12790	COG0163	prenyltransferase activity
KCTCHS21_RS12795	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KCTCHS21_RS12810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KCTCHS21_RS12815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCTCHS21_RS12820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCTCHS21_RS12825	COG4401	Chorismate mutase type I
KCTCHS21_RS12845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCTCHS21_RS12850	COG0134	indole-3-glycerol-phosphate synthase activity
KCTCHS21_RS12855	COG0135	phosphoribosylanthranilate isomerase activity
KCTCHS21_RS12860	COG0133	tryptophan synthase activity
KCTCHS21_RS12865	COG0159	tryptophan synthase activity
KCTCHS21_RS12870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCTCHS21_RS12875	COG0287	Prephenate dehydrogenase
KCTCHS21_RS12895	COG0406	alpha-ribazole phosphatase activity
KCTCHS21_RS12920	COG0723	plastoquinol--plastocyanin reductase activity
KCTCHS21_RS12925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCTCHS21_RS12935	COG4347	Protein of unknown function (DUF1405)
KCTCHS21_RS12945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS12950	COG1694	Mazg nucleotide pyrophosphohydrolase
KCTCHS21_RS12960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KCTCHS21_RS12965	COG1803	Methylglyoxal synthase
KCTCHS21_RS12970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCTCHS21_RS12975	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS12980	COG0617	tRNA 3'-terminal CCA addition
KCTCHS21_RS12990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KCTCHS21_RS12995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KCTCHS21_RS13000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KCTCHS21_RS13010	COG1199	ATP-dependent helicase activity
KCTCHS21_RS13010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCTCHS21_RS13015	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCTCHS21_RS13020	COG0402	S-adenosylhomocysteine deaminase activity
KCTCHS21_RS13035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCTCHS21_RS13040	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS13050	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCTCHS21_RS13055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCTCHS21_RS13060	COG3935	DnaD domain protein
KCTCHS21_RS13065	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KCTCHS21_RS13070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCTCHS21_RS13075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCTCHS21_RS13080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCTCHS21_RS13085	COG0436	Aminotransferase
KCTCHS21_RS13090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCTCHS21_RS13095	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS13100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCTCHS21_RS13105	COG0066	3-isopropylmalate dehydratase activity
KCTCHS21_RS13110	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS13120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCTCHS21_RS13125	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCTCHS21_RS13130	COG1132	(ABC) transporter
KCTCHS21_RS13135	COG1132	(ABC) transporter
KCTCHS21_RS13150	COG1131	(ABC) transporter
KCTCHS21_RS13165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCTCHS21_RS13175	COG2843	Capsule synthesis protein
KCTCHS21_RS13185	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS13190	COG5002	protein histidine kinase activity
KCTCHS21_RS13195	COG1396	sequence-specific DNA binding
KCTCHS21_RS13215	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS13220	COG3850	Histidine kinase
KCTCHS21_RS13220	COG5002	protein histidine kinase activity
KCTCHS21_RS13230	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS13235	COG0772	Belongs to the SEDS family
KCTCHS21_RS13240	COG2207	Transcriptional regulator
KCTCHS21_RS13245	COG2140	Oxalate decarboxylase
KCTCHS21_RS13265	COG0702	epimerase
KCTCHS21_RS13280	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS13280	COG2972	Histidine kinase
KCTCHS21_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS13315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCTCHS21_RS13320	COG0765	amino acid transport
KCTCHS21_RS13325	COG0765	amino acid transport
KCTCHS21_RS13330	COG1126	abc transporter atp-binding protein
KCTCHS21_RS13335	COG1335	isochorismatase
KCTCHS21_RS13340	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS13345	COG1942	4-Oxalocrotonate Tautomerase
KCTCHS21_RS13355	COG2249	NAD(P)H dehydrogenase (quinone) activity
KCTCHS21_RS13360	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS13380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCTCHS21_RS13385	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCTCHS21_RS13395	COG2207	Transcriptional regulator
KCTCHS21_RS13395	COG3708	Transcriptional regulator
KCTCHS21_RS13425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCTCHS21_RS13455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS13460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCTCHS21_RS13465	COG1012	belongs to the aldehyde dehydrogenase family
KCTCHS21_RS13485	COG1361	Conserved repeat domain
KCTCHS21_RS13490	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS13505	COG0596	Alpha beta hydrolase
KCTCHS21_RS13535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KCTCHS21_RS13540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS13545	COG2197	response regulator
KCTCHS21_RS13605	COG1361	Conserved repeat domain
KCTCHS21_RS13610	COG0477	Major facilitator Superfamily
KCTCHS21_RS13615	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS13650	COG1131	(ABC) transporter
KCTCHS21_RS13660	COG1175	transmembrane transport
KCTCHS21_RS13665	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS13670	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS13675	COG2201	protein-glutamate methylesterase activity
KCTCHS21_RS13685	COG0626	cystathionine gamma-synthase activity
KCTCHS21_RS13710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCTCHS21_RS13760	COG1725	Transcriptional regulator
KCTCHS21_RS13775	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS13780	COG1917	Cupin 2, conserved barrel domain protein
KCTCHS21_RS13780	COG2207	Transcriptional regulator
KCTCHS21_RS13800	COG0561	phosphatase activity
KCTCHS21_RS13805	COG1846	Transcriptional regulator
KCTCHS21_RS13820	COG1522	sequence-specific DNA binding
KCTCHS21_RS13835	COG2378	regulation of single-species biofilm formation
KCTCHS21_RS13850	COG1741	Belongs to the pirin family
KCTCHS21_RS13870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KCTCHS21_RS13875	COG0640	Transcriptional regulator
KCTCHS21_RS13885	COG0596	Alpha beta hydrolase
KCTCHS21_RS13890	COG3682	Transcriptional regulator
KCTCHS21_RS13905	COG3682	Transcriptional regulator
KCTCHS21_RS13930	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS13935	COG2207	Transcriptional regulator
KCTCHS21_RS13935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS13945	COG1175	transmembrane transport
KCTCHS21_RS13950	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS13955	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS13975	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS13980	COG2207	Transcriptional regulator
KCTCHS21_RS13985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS13995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS14000	COG0778	Nitroreductase
KCTCHS21_RS14005	COG2207	Transcriptional regulator
KCTCHS21_RS14020	COG3588	fructose-bisphosphate aldolase
KCTCHS21_RS14030	COG1309	transcriptional regulator
KCTCHS21_RS14035	COG2814	Major facilitator Superfamily
KCTCHS21_RS14090	COG0194	GDP metabolic process
KCTCHS21_RS14095	COG0667	Aldo Keto reductase
KCTCHS21_RS14100	COG0300	oxidoreductase activity
KCTCHS21_RS14105	COG0789	Transcriptional regulator
KCTCHS21_RS14145	COG3620	sequence-specific DNA binding
KCTCHS21_RS14150	COG0529	Catalyzes the synthesis of activated sulfate
KCTCHS21_RS14175	COG4977	sequence-specific DNA binding
KCTCHS21_RS14210	COG1361	Conserved repeat domain
KCTCHS21_RS14215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCTCHS21_RS14225	COG0604	alcohol dehydrogenase
KCTCHS21_RS14235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCTCHS21_RS14255	COG3290	protein histidine kinase activity
KCTCHS21_RS14260	COG2207	Transcriptional regulator
KCTCHS21_RS14260	COG4753	response regulator
KCTCHS21_RS14265	COG1653	transport
KCTCHS21_RS14280	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS14285	COG0456	acetyltransferase
KCTCHS21_RS14290	COG2972	Histidine kinase
KCTCHS21_RS14295	COG4753	response regulator
KCTCHS21_RS14295	COG2207	Transcriptional regulator
KCTCHS21_RS14305	COG1175	transmembrane transport
KCTCHS21_RS14310	COG3833	ABC-type maltose transport systems, permease component
KCTCHS21_RS14330	COG1361	Conserved repeat domain
KCTCHS21_RS14335	COG1902	pentaerythritol trinitrate reductase activity
KCTCHS21_RS14340	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS14345	COG2378	regulation of single-species biofilm formation
KCTCHS21_RS14360	COG3173	Aminoglycoside phosphotransferase
KCTCHS21_RS14405	COG1024	Enoyl-CoA hydratase
KCTCHS21_RS14415	COG0657	acetylesterase activity
KCTCHS21_RS14420	COG0789	Transcriptional regulator
KCTCHS21_RS14425	COG0667	Aldo Keto reductase
KCTCHS21_RS14435	COG0693	protein deglycase activity
KCTCHS21_RS14445	COG2814	Major facilitator Superfamily
KCTCHS21_RS14450	COG1309	transcriptional regulator
KCTCHS21_RS14520	COG2814	Major facilitator Superfamily
KCTCHS21_RS14525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCTCHS21_RS14530	COG0477	Major facilitator Superfamily
KCTCHS21_RS14535	COG0789	Transcriptional regulator
KCTCHS21_RS14535	COG4978	Transcriptional regulator
KCTCHS21_RS14540	COG2249	NAD(P)H dehydrogenase (quinone) activity
KCTCHS21_RS14545	COG4753	response regulator
KCTCHS21_RS14545	COG2207	Transcriptional regulator
KCTCHS21_RS14555	COG2207	Transcriptional regulator
KCTCHS21_RS14580	COG1653	transport
KCTCHS21_RS14585	COG1175	transmembrane transport
KCTCHS21_RS14590	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS14595	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS14600	COG4753	response regulator
KCTCHS21_RS14600	COG2207	Transcriptional regulator
KCTCHS21_RS14605	COG1070	Carbohydrate kinase
KCTCHS21_RS14610	COG0246	Mannitol dehydrogenase
KCTCHS21_RS14615	COG0246	Mannitol dehydrogenase
KCTCHS21_RS14620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCTCHS21_RS14655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS14695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS14700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS14705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS14745	COG0110	maltose O-acetyltransferase activity
KCTCHS21_RS14750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCTCHS21_RS14760	COG1309	transcriptional regulator
KCTCHS21_RS14765	COG4221	oxidoreductase activity
KCTCHS21_RS14795	COG0477	Major facilitator Superfamily
KCTCHS21_RS14810	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS14815	COG0667	Aldo Keto reductase
KCTCHS21_RS14840	COG1547	Domain of unknown function (DUF309)
KCTCHS21_RS14845	COG0288	reversible hydration of carbon dioxide
KCTCHS21_RS14855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KCTCHS21_RS14875	COG1233	COG1233 Phytoene dehydrogenase and related
KCTCHS21_RS14905	COG1562	ergosterol biosynthetic process
KCTCHS21_RS14930	COG1304	FMN binding
KCTCHS21_RS14935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCTCHS21_RS14945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCTCHS21_RS14950	COG2136	Putative SAM-dependent methyltransferase
KCTCHS21_RS14950	COG2521	methyltransferase
KCTCHS21_RS14955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCTCHS21_RS14960	COG1923	regulation of RNA biosynthetic process
KCTCHS21_RS14965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCTCHS21_RS14980	COG0464	growth
KCTCHS21_RS14985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCTCHS21_RS14990	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KCTCHS21_RS14995	COG0789	Transcriptional regulator
KCTCHS21_RS15000	COG0174	glutamine synthetase
KCTCHS21_RS15010	COG2720	vancomycin resistance protein
KCTCHS21_RS15020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCTCHS21_RS15030	COG4224	UPF0291 protein
KCTCHS21_RS15040	COG1011	Hydrolase
KCTCHS21_RS15045	COG0646	methionine synthase
KCTCHS21_RS15045	COG1410	methionine synthase
KCTCHS21_RS15055	COG1205	dead DEAH box helicase
KCTCHS21_RS15055	COG1111	helicase
KCTCHS21_RS15065	COG0647	UMP catabolic process
KCTCHS21_RS15070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCTCHS21_RS15075	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KCTCHS21_RS15090	COG1119	ATPase activity
KCTCHS21_RS15095	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KCTCHS21_RS15105	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15110	COG3850	Histidine kinase
KCTCHS21_RS15110	COG5002	protein histidine kinase activity
KCTCHS21_RS15115	COG0791	NLP P60 protein
KCTCHS21_RS15120	COG0456	acetyltransferase
KCTCHS21_RS15130	COG0321	lipoyl(octanoyl) transferase activity
KCTCHS21_RS15130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KCTCHS21_RS15140	COG2860	membrane
KCTCHS21_RS15145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCTCHS21_RS15180	COG1607	acyl-coa hydrolase
KCTCHS21_RS15185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCTCHS21_RS15195	COG0493	'glutamate synthase
KCTCHS21_RS15220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KCTCHS21_RS15240	COG0674	pyruvate-flavodoxin oxidoreductase activity
KCTCHS21_RS15280	COG0667	Aldo Keto reductase
KCTCHS21_RS15285	COG0523	cobalamin synthesis protein
KCTCHS21_RS15325	COG5002	protein histidine kinase activity
KCTCHS21_RS15330	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15340	COG1136	(ABC) transporter
KCTCHS21_RS15345	COG0577	efflux transmembrane transporter activity
KCTCHS21_RS15345	COG1136	(ABC) transporter
KCTCHS21_RS15350	COG1408	metallophosphoesterase
KCTCHS21_RS15355	COG1494	fructose-1,6-bisphosphatase
KCTCHS21_RS15360	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS15360	COG3347	Dehydrogenase
KCTCHS21_RS15375	COG1070	Carbohydrate kinase
KCTCHS21_RS15380	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS15385	COG0247	lactate metabolic process
KCTCHS21_RS15390	COG1139	Iron-sulfur cluster binding protein
KCTCHS21_RS15395	COG1556	Lactate utilization protein
KCTCHS21_RS15400	COG2186	Transcriptional regulator
KCTCHS21_RS15410	COG0653	protein targeting
KCTCHS21_RS15415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KCTCHS21_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS15425	COG1649	PFAM Uncharacterised BCR, COG1649
KCTCHS21_RS15425	COG0726	polysaccharide deacetylase
KCTCHS21_RS15430	COG2814	Major facilitator Superfamily
KCTCHS21_RS15455	COG1247	-acetyltransferase
KCTCHS21_RS15460	COG0488	(ABC) transporter
KCTCHS21_RS15480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCTCHS21_RS15485	COG2318	DinB family
KCTCHS21_RS15490	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15495	COG0784	Response regulator, receiver
KCTCHS21_RS15495	COG2205	protein histidine kinase activity
KCTCHS21_RS15495	COG5002	protein histidine kinase activity
KCTCHS21_RS15505	COG5002	protein histidine kinase activity
KCTCHS21_RS15510	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15515	COG1132	(ABC) transporter
KCTCHS21_RS15525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCTCHS21_RS15530	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
KCTCHS21_RS15540	COG1175	transmembrane transport
KCTCHS21_RS15545	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS15550	COG2972	Histidine kinase
KCTCHS21_RS15555	COG2207	Transcriptional regulator
KCTCHS21_RS15555	COG4753	response regulator
KCTCHS21_RS15595	COG0640	Transcriptional regulator
KCTCHS21_RS15610	COG0640	Transcriptional regulator
KCTCHS21_RS15620	COG2843	Capsule synthesis protein
KCTCHS21_RS15655	COG3214	Protein conserved in bacteria
KCTCHS21_RS15665	COG1063	alcohol dehydrogenase
KCTCHS21_RS15670	COG1309	transcriptional regulator
KCTCHS21_RS15680	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KCTCHS21_RS15685	COG0011	TIGRFAM Protein of
KCTCHS21_RS15690	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15695	COG2205	protein histidine kinase activity
KCTCHS21_RS15700	COG1136	(ABC) transporter
KCTCHS21_RS15705	COG0577	efflux transmembrane transporter activity
KCTCHS21_RS15720	COG1846	Transcriptional regulator
KCTCHS21_RS15725	COG2814	Major facilitator Superfamily
KCTCHS21_RS15735	COG0346	lactoylglutathione lyase activity
KCTCHS21_RS15755	COG1846	Transcriptional regulator
KCTCHS21_RS15830	COG2409	Drug exporters of the RND superfamily
KCTCHS21_RS15870	COG1309	transcriptional regulator
KCTCHS21_RS15905	COG1309	transcriptional regulator
KCTCHS21_RS15925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCTCHS21_RS15930	COG0785	Cytochrome C biogenesis protein
KCTCHS21_RS15940	COG2205	protein histidine kinase activity
KCTCHS21_RS15945	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15960	COG4886	Leucine-rich repeat (LRR) protein
KCTCHS21_RS15970	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS15970	COG2972	Histidine kinase
KCTCHS21_RS15990	COG2409	Drug exporters of the RND superfamily
KCTCHS21_RS15990	COG1033	growth of symbiont in host cell
KCTCHS21_RS15995	COG2814	Major facilitator Superfamily
KCTCHS21_RS16025	COG1131	(ABC) transporter
KCTCHS21_RS16055	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS16080	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KCTCHS21_RS16085	COG1737	Transcriptional regulator
KCTCHS21_RS16095	COG2217	Heavy metal translocating P-type atpase
KCTCHS21_RS16100	COG2608	mercury ion transmembrane transporter activity
KCTCHS21_RS16110	COG1937	Protein conserved in bacteria
KCTCHS21_RS16120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCTCHS21_RS16125	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS16145	COG0667	Aldo Keto reductase
KCTCHS21_RS16155	COG1309	transcriptional regulator
KCTCHS21_RS16190	COG0251	oxidation-reduction process
KCTCHS21_RS16200	COG1802	Transcriptional regulator
KCTCHS21_RS16210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCTCHS21_RS16215	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS16220	COG4209	transmembrane transport
KCTCHS21_RS16230	COG2207	Transcriptional regulator
KCTCHS21_RS16230	COG4753	response regulator
KCTCHS21_RS16235	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS16245	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS16255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCTCHS21_RS16255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCTCHS21_RS16260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCTCHS21_RS16265	COG0785	Cytochrome C biogenesis protein
KCTCHS21_RS16270	COG5002	protein histidine kinase activity
KCTCHS21_RS16275	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS16285	COG2814	Major facilitator Superfamily
KCTCHS21_RS16330	COG2226	methyltransferase
KCTCHS21_RS16350	COG0640	Transcriptional regulator
KCTCHS21_RS16365	COG0366	Alpha amylase catalytic
KCTCHS21_RS16380	COG2182	Extracellular solute-binding protein
KCTCHS21_RS16385	COG4753	response regulator
KCTCHS21_RS16385	COG2207	Transcriptional regulator
KCTCHS21_RS16390	COG2972	Histidine kinase
KCTCHS21_RS16415	COG0477	Major facilitator Superfamily
KCTCHS21_RS16420	COG0492	ferredoxin-NADP+ reductase activity
KCTCHS21_RS16430	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS16435	COG2070	2-Nitropropane dioxygenase
KCTCHS21_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS16460	COG0277	FAD linked oxidase domain protein
KCTCHS21_RS16465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCTCHS21_RS16475	COG3250	beta-galactosidase activity
KCTCHS21_RS16480	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS16485	COG1175	transmembrane transport
KCTCHS21_RS16495	COG4753	response regulator
KCTCHS21_RS16495	COG2207	Transcriptional regulator
KCTCHS21_RS16500	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS16525	COG0714	Associated with various cellular activities
KCTCHS21_RS16555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCTCHS21_RS16570	COG1846	Transcriptional regulator
KCTCHS21_RS16575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCTCHS21_RS16580	COG1959	2 iron, 2 sulfur cluster binding
KCTCHS21_RS16600	COG0640	Transcriptional regulator
KCTCHS21_RS16605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCTCHS21_RS16610	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS16615	COG1175	transmembrane transport
KCTCHS21_RS16625	COG1215	transferase activity, transferring glycosyl groups
KCTCHS21_RS16635	COG3850	Histidine kinase
KCTCHS21_RS16635	COG5002	protein histidine kinase activity
KCTCHS21_RS16640	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS16655	COG2115	Belongs to the xylose isomerase family
KCTCHS21_RS16660	COG0662	Cupin 2, conserved barrel domain protein
KCTCHS21_RS16660	COG2207	Transcriptional regulator
KCTCHS21_RS16665	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS16675	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS16680	COG1175	transmembrane transport
KCTCHS21_RS16690	COG1082	Xylose isomerase domain protein TIM barrel
KCTCHS21_RS16695	COG1063	alcohol dehydrogenase
KCTCHS21_RS16700	COG0586	Pfam SNARE associated Golgi protein
KCTCHS21_RS16710	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS16720	COG2897	thiosulfate sulfurtransferase activity
KCTCHS21_RS16725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCTCHS21_RS16750	COG1309	transcriptional regulator
KCTCHS21_RS16755	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS16795	COG0488	(ABC) transporter
KCTCHS21_RS16810	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS16825	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS16880	COG2814	Major facilitator Superfamily
KCTCHS21_RS16895	COG1132	(ABC) transporter
KCTCHS21_RS16900	COG0390	transport system, permease component
KCTCHS21_RS16905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCTCHS21_RS16925	COG0475	glutathione-regulated potassium exporter activity
KCTCHS21_RS16930	COG5002	protein histidine kinase activity
KCTCHS21_RS16935	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS16980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCTCHS21_RS16985	COG0726	polysaccharide deacetylase
KCTCHS21_RS16995	COG0697	spore germination
KCTCHS21_RS17025	COG0640	Transcriptional regulator
KCTCHS21_RS17030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KCTCHS21_RS17035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCTCHS21_RS17095	COG1357	PFAM Pentapeptide repeats (8 copies)
KCTCHS21_RS17100	COG0402	S-adenosylhomocysteine deaminase activity
KCTCHS21_RS17110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KCTCHS21_RS17115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCTCHS21_RS17125	COG0640	Transcriptional regulator
KCTCHS21_RS17140	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS17150	COG1653	transport
KCTCHS21_RS17155	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS17160	COG1609	Transcriptional regulator
KCTCHS21_RS17180	COG4974	Belongs to the 'phage' integrase family
KCTCHS21_RS17195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCTCHS21_RS17200	COG0531	amino acid
KCTCHS21_RS17210	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS17215	COG2205	protein histidine kinase activity
KCTCHS21_RS17220	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS17235	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS17240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KCTCHS21_RS17250	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS17260	COG1785	Belongs to the alkaline phosphatase family
KCTCHS21_RS17280	COG0697	spore germination
KCTCHS21_RS17290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCTCHS21_RS17315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS17340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCTCHS21_RS17350	COG1454	alcohol dehydrogenase
KCTCHS21_RS17350	COG1012	belongs to the aldehyde dehydrogenase family
KCTCHS21_RS17380	COG2032	superoxide dismutase activity
KCTCHS21_RS17395	COG0705	Rhomboid family
KCTCHS21_RS17400	COG0697	spore germination
KCTCHS21_RS17405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCTCHS21_RS17410	COG4509	Sortase family
KCTCHS21_RS17435	COG0501	Belongs to the peptidase M48B family
KCTCHS21_RS17465	COG0789	Transcriptional regulator
KCTCHS21_RS17475	COG0628	permease
KCTCHS21_RS17490	COG2217	Heavy metal translocating P-type atpase
KCTCHS21_RS17495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCTCHS21_RS17500	COG0805	protein transport
KCTCHS21_RS17520	COG0772	Belongs to the SEDS family
KCTCHS21_RS17525	COG1695	Transcriptional regulator
KCTCHS21_RS17530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KCTCHS21_RS17555	COG0436	Aminotransferase
KCTCHS21_RS17570	COG0681	Belongs to the peptidase S26 family
KCTCHS21_RS17580	COG1511	domain protein
KCTCHS21_RS17585	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCTCHS21_RS17595	COG2197	response regulator
KCTCHS21_RS17600	COG2203	Gaf domain
KCTCHS21_RS17600	COG4585	Histidine kinase
KCTCHS21_RS17605	COG2720	vancomycin resistance protein
KCTCHS21_RS17620	COG1132	(ABC) transporter
KCTCHS21_RS17630	COG2217	Heavy metal translocating P-type atpase
KCTCHS21_RS17645	COG1054	Belongs to the UPF0176 family
KCTCHS21_RS17655	COG5002	protein histidine kinase activity
KCTCHS21_RS17660	COG3239	Fatty acid desaturase
KCTCHS21_RS17665	COG4585	Histidine kinase
KCTCHS21_RS17670	COG2197	response regulator
KCTCHS21_RS17675	COG5263	repeat protein
KCTCHS21_RS17675	COG4193	domain, Protein
KCTCHS21_RS17695	COG1201	RNA secondary structure unwinding
KCTCHS21_RS17700	COG1132	(ABC) transporter
KCTCHS21_RS17705	COG0454	-acetyltransferase
KCTCHS21_RS17725	COG0584	glycerophosphoryl diester phosphodiesterase
KCTCHS21_RS17735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCTCHS21_RS17740	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCTCHS21_RS17745	COG2323	membrane
KCTCHS21_RS17755	COG1199	ATP-dependent helicase activity
KCTCHS21_RS17765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCTCHS21_RS17775	COG3344	reverse transcriptase
KCTCHS21_RS17805	COG1361	Conserved repeat domain
KCTCHS21_RS17840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCTCHS21_RS17855	COG0477	Major facilitator Superfamily
KCTCHS21_RS17870	COG3386	PFAM SMP-30 Gluconolaconase
KCTCHS21_RS17895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS17900	COG1227	inorganic diphosphatase activity
KCTCHS21_RS17905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KCTCHS21_RS17910	COG2169	Transcriptional regulator
KCTCHS21_RS17915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCTCHS21_RS17920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCTCHS21_RS17920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCTCHS21_RS17930	COG1649	PFAM Uncharacterised BCR, COG1649
KCTCHS21_RS17965	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS17995	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KCTCHS21_RS18005	COG3639	organic phosphonate transmembrane transporter activity
KCTCHS21_RS18010	COG0737	Belongs to the 5'-nucleotidase family
KCTCHS21_RS18020	COG1320	monovalent cation:proton antiporter activity
KCTCHS21_RS18025	COG2212	antiporter activity
KCTCHS21_RS18030	COG1863	multisubunit Na H antiporter MnhE subunit
KCTCHS21_RS18035	COG0651	ATP synthesis coupled electron transport
KCTCHS21_RS18040	COG1006	Multisubunit Na H antiporter MnhC subunit
KCTCHS21_RS18045	COG2111	Na H antiporter
KCTCHS21_RS18050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCTCHS21_RS18050	COG2111	Na H antiporter
KCTCHS21_RS18060	COG0582	viral genome integration into host DNA
KCTCHS21_RS18075	COG2207	Transcriptional regulator
KCTCHS21_RS18105	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS18110	COG1175	transmembrane transport
KCTCHS21_RS18140	COG1011	Hydrolase
KCTCHS21_RS18145	COG2375	cellular response to nickel ion
KCTCHS21_RS18145	COG1132	(ABC) transporter
KCTCHS21_RS18155	COG0778	Nitroreductase
KCTCHS21_RS18160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCTCHS21_RS18175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCTCHS21_RS18180	COG1321	iron dependent repressor
KCTCHS21_RS18180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCTCHS21_RS18185	COG1121	(ABC) transporter
KCTCHS21_RS18190	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCTCHS21_RS18220	COG2814	Major facilitator Superfamily
KCTCHS21_RS18305	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS18315	COG2814	Major facilitator Superfamily
KCTCHS21_RS18320	COG1122	ATPase activity
KCTCHS21_RS18325	COG1122	ATPase activity
KCTCHS21_RS18330	COG1268	BioY protein
KCTCHS21_RS18340	COG4550	Control of competence regulator ComK, YlbF/YmcA
KCTCHS21_RS18345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCTCHS21_RS18350	COG4869	propanediol catabolic process
KCTCHS21_RS18355	COG1013	pyruvate-flavodoxin oxidoreductase activity
KCTCHS21_RS18360	COG0674	pyruvate-flavodoxin oxidoreductase activity
KCTCHS21_RS18360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KCTCHS21_RS18370	COG2359	stage V sporulation protein S
KCTCHS21_RS18375	COG1692	metallophosphoesterase
KCTCHS21_RS18380	COG1418	mRNA catabolic process
KCTCHS21_RS18390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCTCHS21_RS18400	COG1546	Belongs to the CinA family
KCTCHS21_RS18400	COG1058	Belongs to the CinA family
KCTCHS21_RS18405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCTCHS21_RS18410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCTCHS21_RS18420	COG1426	Protein conserved in bacteria
KCTCHS21_RS18440	COG0612	Peptidase, M16
KCTCHS21_RS18445	COG0612	Peptidase, M16
KCTCHS21_RS18455	COG1674	ftsk spoiiie
KCTCHS21_RS18465	COG0740	serine-type endopeptidase activity
KCTCHS21_RS18470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCTCHS21_RS18475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCTCHS21_RS18480	COG0527	aspartate kinase activity
KCTCHS21_RS18485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCTCHS21_RS18490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCTCHS21_RS18495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCTCHS21_RS18505	COG0756	dUTP diphosphatase activity
KCTCHS21_RS18510	COG0612	Peptidase, M16
KCTCHS21_RS18515	COG0726	polysaccharide deacetylase
KCTCHS21_RS18520	COG1185	polyribonucleotide nucleotidyltransferase activity
KCTCHS21_RS18525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCTCHS21_RS18530	COG0196	riboflavin kinase activity
KCTCHS21_RS18535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCTCHS21_RS18540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KCTCHS21_RS18545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCTCHS21_RS18550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCTCHS21_RS18550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCTCHS21_RS18555	COG1358	cellular component organization or biogenesis
KCTCHS21_RS18560	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KCTCHS21_RS18565	COG0195	Participates in both transcription termination and antitermination
KCTCHS21_RS18570	COG0779	Required for maturation of 30S ribosomal subunits
KCTCHS21_RS18575	COG2176	DNA-directed DNA polymerase activity
KCTCHS21_RS18580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCTCHS21_RS18585	COG0750	zinc metalloprotease
KCTCHS21_RS18590	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KCTCHS21_RS18595	COG4589	Belongs to the CDS family
KCTCHS21_RS18600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCTCHS21_RS18605	COG0233	cytoplasmic translational termination
KCTCHS21_RS18610	COG0528	UMP kinase activity
KCTCHS21_RS18615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCTCHS21_RS18620	COG0052	Belongs to the universal ribosomal protein uS2 family
KCTCHS21_RS18645	COG1191	sigma factor activity
KCTCHS21_RS18655	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KCTCHS21_RS18660	COG1776	CheC inhibitor of MCP methylation
KCTCHS21_RS18665	COG0835	chemotaxis
KCTCHS21_RS18670	COG0643	Histidine kinase
KCTCHS21_RS18670	COG2198	Histidine kinase
KCTCHS21_RS18675	COG2201	protein-glutamate methylesterase activity
KCTCHS21_RS18680	COG0455	bacterial-type flagellum organization
KCTCHS21_RS18685	COG1419	protein localization to endoplasmic reticulum
KCTCHS21_RS18690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCTCHS21_RS18695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCTCHS21_RS18700	COG1684	flagellar biosynthetic protein fliR
KCTCHS21_RS18705	COG1987	bacterial-type flagellum assembly
KCTCHS21_RS18710	COG1338	Plays a role in the flagellum-specific transport system
KCTCHS21_RS18720	COG2201	protein-glutamate methylesterase activity
KCTCHS21_RS18725	COG1776	CheC inhibitor of MCP methylation
KCTCHS21_RS18725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCTCHS21_RS18730	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCTCHS21_RS18740	COG1582	Flagellar protein (FlbD)
KCTCHS21_RS18745	COG4786	Flagellar basal body rod
KCTCHS21_RS18755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KCTCHS21_RS18775	COG1157	protein secretion by the type III secretion system
KCTCHS21_RS18785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCTCHS21_RS18790	COG1766	The M ring may be actively involved in energy transduction
KCTCHS21_RS18795	COG1677	Flagellar hook-basal body complex protein FliE
KCTCHS21_RS18800	COG1558	bacterial-type flagellum-dependent cell motility
KCTCHS21_RS18805	COG1815	bacterial-type flagellum-dependent cell motility
KCTCHS21_RS18810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCTCHS21_RS18815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCTCHS21_RS18820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KCTCHS21_RS18825	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCTCHS21_RS18830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCTCHS21_RS18835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCTCHS21_RS18835	COG0758	DNA mediated transformation
KCTCHS21_RS18840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KCTCHS21_RS18845	COG0045	succinate-CoA ligase (ADP-forming) activity
KCTCHS21_RS18855	COG2357	RelA SpoT domain protein
KCTCHS21_RS18860	COG0330	HflC and HflK could
KCTCHS21_RS18865	COG0330	HflC and HflK could
KCTCHS21_RS18870	COG0792	nuclease activity
KCTCHS21_RS18875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCTCHS21_RS18885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCTCHS21_RS18900	COG3011	Protein conserved in bacteria
KCTCHS21_RS18905	COG2197	response regulator
KCTCHS21_RS18915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCTCHS21_RS18925	COG0335	large ribosomal subunit rRNA binding
KCTCHS21_RS18935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCTCHS21_RS18940	COG1837	Belongs to the UPF0109 family
KCTCHS21_RS18945	COG0228	four-way junction DNA binding
KCTCHS21_RS18950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCTCHS21_RS18960	COG0552	protein localization to endoplasmic reticulum
KCTCHS21_RS18965	COG1196	nuclear chromosome segregation
KCTCHS21_RS18970	COG0571	ribonuclease III activity
KCTCHS21_RS18975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCTCHS21_RS18980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCTCHS21_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS18990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCTCHS21_RS18995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCTCHS21_RS19000	COG0416	fatty acid biosynthetic process
KCTCHS21_RS19005	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS19010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KCTCHS21_RS19020	COG1323	Belongs to the UPF0348 family
KCTCHS21_RS19025	COG3314	Sporulation integral membrane protein YlbJ
KCTCHS21_RS19030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCTCHS21_RS19035	COG0742	ribosomal rna small subunit methyltransferase
KCTCHS21_RS19075	COG1742	UPF0060 membrane protein
KCTCHS21_RS19105	COG0697	spore germination
KCTCHS21_RS19115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS19125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCTCHS21_RS19140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCTCHS21_RS19145	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS19145	COG0457	Tetratricopeptide repeat
KCTCHS21_RS19160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCTCHS21_RS19165	COG1307	EDD domain protein, DegV family
KCTCHS21_RS19170	COG1461	Dihydroxyacetone kinase
KCTCHS21_RS19175	COG1302	Protein conserved in bacteria
KCTCHS21_RS19180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KCTCHS21_RS19190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KCTCHS21_RS19195	COG1162	GTPase activity
KCTCHS21_RS19200	COG0515	serine threonine protein kinase
KCTCHS21_RS19200	COG2815	serine threonine protein kinase
KCTCHS21_RS19205	COG0631	protein serine/threonine phosphatase activity
KCTCHS21_RS19215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCTCHS21_RS19215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCTCHS21_RS19225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCTCHS21_RS19230	COG0242	peptide deformylase activity
KCTCHS21_RS19235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCTCHS21_RS19240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCTCHS21_RS19245	COG1758	RNA polymerase activity
KCTCHS21_RS19250	COG0194	GDP metabolic process
KCTCHS21_RS19255	COG2052	Domain of unknown function (DUF370)
KCTCHS21_RS19260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KCTCHS21_RS19260	COG0646	methionine synthase
KCTCHS21_RS19265	COG2814	Major facilitator Superfamily
KCTCHS21_RS19280	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KCTCHS21_RS19285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KCTCHS21_RS19295	COG0613	PHP domain protein
KCTCHS21_RS19330	COG1473	amidohydrolase
KCTCHS21_RS19340	COG0772	Belongs to the SEDS family
KCTCHS21_RS19345	COG1302	Protein conserved in bacteria
KCTCHS21_RS19350	COG0387	Pfam Sodium calcium exchanger
KCTCHS21_RS19355	COG4838	Belongs to the UPF0358 family
KCTCHS21_RS19365	COG2309	aminopeptidase activity
KCTCHS21_RS19375	COG2199	diguanylate cyclase activity
KCTCHS21_RS19375	COG2203	Gaf domain
KCTCHS21_RS19380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCTCHS21_RS19395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCTCHS21_RS19400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCTCHS21_RS19405	COG0454	-acetyltransferase
KCTCHS21_RS19410	COG0123	including yeast histone deacetylase and acetoin utilization protein
KCTCHS21_RS19415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCTCHS21_RS19420	COG1609	Transcriptional regulator
KCTCHS21_RS19445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCTCHS21_RS19450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCTCHS21_RS19450	COG1263	PTS System
KCTCHS21_RS19450	COG2190	(PTS) system
KCTCHS21_RS19455	COG1832	CoA-binding protein
KCTCHS21_RS19460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KCTCHS21_RS19465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCTCHS21_RS19470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCTCHS21_RS19475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCTCHS21_RS19480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCTCHS21_RS19485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KCTCHS21_RS19510	COG1131	(ABC) transporter
KCTCHS21_RS19515	COG4585	Histidine kinase
KCTCHS21_RS19520	COG2197	response regulator
KCTCHS21_RS19525	COG4493	Belongs to the UPF0637 family
KCTCHS21_RS19540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCTCHS21_RS19550	COG1982	Orn Lys Arg decarboxylase major
KCTCHS21_RS19580	COG1234	tRNA 3'-trailer cleavage
KCTCHS21_RS19655	COG1793	dna ligase
KCTCHS21_RS19660	COG2155	Conserved Protein
KCTCHS21_RS19665	COG0519	Catalyzes the synthesis of GMP from XMP
KCTCHS21_RS19670	COG0154	amidase activity
KCTCHS21_RS19675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCTCHS21_RS19685	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS19690	COG3842	ATPase activity
KCTCHS21_RS19700	COG1177	transmembrane transport
KCTCHS21_RS19725	COG0658	competence protein
KCTCHS21_RS19725	COG2333	competence protein COMEC
KCTCHS21_RS19745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCTCHS21_RS19775	COG3093	addiction module antidote protein HigA
KCTCHS21_RS19780	COG1653	transport
KCTCHS21_RS19785	COG1136	(ABC) transporter
KCTCHS21_RS19790	COG4591	ABC-type transport system involved in lipoprotein release permease component
KCTCHS21_RS19800	COG1136	(ABC) transporter
KCTCHS21_RS19805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCTCHS21_RS19810	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS19820	COG1131	(ABC) transporter
KCTCHS21_RS19835	COG0284	orotidine-5'-phosphate decarboxylase activity
KCTCHS21_RS19840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCTCHS21_RS19850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCTCHS21_RS19855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCTCHS21_RS19860	COG0436	Aminotransferase
KCTCHS21_RS19865	COG0564	pseudouridine synthase activity
KCTCHS21_RS19875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCTCHS21_RS19890	COG3599	regulation of cell shape
KCTCHS21_RS19895	COG2302	S4 RNA-binding domain
KCTCHS21_RS19900	COG0762	integral membrane protein
KCTCHS21_RS19905	COG1799	cell septum assembly
KCTCHS21_RS19910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCTCHS21_RS19915	COG1496	oxidoreductase activity
KCTCHS21_RS19920	COG1873	PFAM PRC-barrel domain
KCTCHS21_RS19930	COG1191	sigma factor activity
KCTCHS21_RS19935	COG1191	sigma factor activity
KCTCHS21_RS19945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCTCHS21_RS19950	COG0849	cell division
KCTCHS21_RS19955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCTCHS21_RS19960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCTCHS21_RS19965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCTCHS21_RS19970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCTCHS21_RS19975	COG0772	Belongs to the SEDS family
KCTCHS21_RS19980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCTCHS21_RS19985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCTCHS21_RS19990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCTCHS21_RS19995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCTCHS21_RS20000	COG0768	penicillin binding
KCTCHS21_RS20005	COG0768	penicillin binding
KCTCHS21_RS20015	COG0275	rRNA processing
KCTCHS21_RS20020	COG2001	Belongs to the MraZ family
KCTCHS21_RS20040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KCTCHS21_RS20045	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KCTCHS21_RS20055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCTCHS21_RS20085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCTCHS21_RS20100	COG1316	TRANSCRIPTIONal
KCTCHS21_RS20115	COG1217	gtp-binding protein TYPA
KCTCHS21_RS20125	COG0861	Integral membrane protein TerC family
KCTCHS21_RS20130	COG0861	Integral membrane protein TerC family
KCTCHS21_RS20135	COG0301	tRNA thio-modification
KCTCHS21_RS20140	COG1104	cysteine desulfurase activity
KCTCHS21_RS20145	COG0741	lytic transglycosylase activity
KCTCHS21_RS20165	COG0154	amidase activity
KCTCHS21_RS20175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCTCHS21_RS20180	COG2384	SAM-dependent methyltransferase
KCTCHS21_RS20195	COG0358	DNA primase activity
KCTCHS21_RS20205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCTCHS21_RS20210	COG0751	glycine-tRNA ligase activity
KCTCHS21_RS20215	COG0752	glycyl-tRNA synthetase alpha subunit
KCTCHS21_RS20220	COG1381	Involved in DNA repair and RecF pathway recombination
KCTCHS21_RS20230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCTCHS21_RS20240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCTCHS21_RS20245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCTCHS21_RS20250	COG1480	7TM receptor with intracellular HD hydrolase
KCTCHS21_RS20255	COG1702	phosphate starvation-inducible protein PhoH
KCTCHS21_RS20275	COG4864	UPF0365 protein
KCTCHS21_RS20280	COG1030	water channel activity
KCTCHS21_RS20290	COG1610	YqeY-like protein
KCTCHS21_RS20295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KCTCHS21_RS20300	COG0537	adenosine 5'-monophosphoramidase activity
KCTCHS21_RS20315	COG1074	ATP-dependent DNA helicase activity
KCTCHS21_RS20320	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KCTCHS21_RS20330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCTCHS21_RS20335	COG1283	sodium-dependent phosphate transmembrane transporter activity
KCTCHS21_RS20345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCTCHS21_RS20350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCTCHS21_RS20355	COG1994	Peptidase M50
KCTCHS21_RS20360	COG2264	protein methyltransferase activity
KCTCHS21_RS20380	COG0443	Heat shock 70 kDa protein
KCTCHS21_RS20390	COG1420	regulation of RNA biosynthetic process
KCTCHS21_RS20400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCTCHS21_RS20405	COG0481	GTPase activity
KCTCHS21_RS20410	COG1193	negative regulation of DNA recombination
KCTCHS21_RS20420	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS20430	COG0268	Binds directly to 16S ribosomal RNA
KCTCHS21_RS20440	COG1466	dna polymerase III delta subunit
KCTCHS21_RS20450	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS20455	COG2333	competence protein COMEC
KCTCHS21_RS20455	COG0658	competence protein
KCTCHS21_RS20470	COG1596	polysaccharide export
KCTCHS21_RS20470	COG1555	photosystem II stabilization
KCTCHS21_RS20475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCTCHS21_RS20480	COG0495	leucyl-tRNA aminoacylation
KCTCHS21_RS20505	COG2226	methyltransferase
KCTCHS21_RS20510	COG2996	Protein conserved in bacteria
KCTCHS21_RS20515	COG0799	negative regulation of ribosome biogenesis
KCTCHS21_RS20520	COG1713	HD superfamily hydrolase involved in NAD metabolism
KCTCHS21_RS20525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCTCHS21_RS20530	COG1534	Rna-binding protein
KCTCHS21_RS20535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCTCHS21_RS20540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCTCHS21_RS20545	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KCTCHS21_RS20560	COG0714	Associated with various cellular activities
KCTCHS21_RS20570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCTCHS21_RS20600	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS20605	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS20610	COG4209	transmembrane transport
KCTCHS21_RS20620	COG1653	transport
KCTCHS21_RS20625	COG2207	Transcriptional regulator
KCTCHS21_RS20650	COG2176	DNA-directed DNA polymerase activity
KCTCHS21_RS20660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCTCHS21_RS20680	COG0628	permease
KCTCHS21_RS20685	COG0768	penicillin binding
KCTCHS21_RS20695	COG0826	peptidase U32
KCTCHS21_RS20700	COG0826	peptidase U32
KCTCHS21_RS20705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCTCHS21_RS20710	COG3906	Belongs to the UPF0473 family
KCTCHS21_RS20715	COG3906	Belongs to the UPF0473 family
KCTCHS21_RS20720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCTCHS21_RS20725	COG4472	Bacterial protein of unknown function (DUF965)
KCTCHS21_RS20735	COG0628	permease
KCTCHS21_RS20750	COG1104	cysteine desulfurase activity
KCTCHS21_RS20755	COG1959	2 iron, 2 sulfur cluster binding
KCTCHS21_RS20760	COG0482	sulfurtransferase activity
KCTCHS21_RS20765	COG0217	transcriptional regulatory protein
KCTCHS21_RS20770	COG2226	methyltransferase
KCTCHS21_RS20790	COG1164	Oligoendopeptidase f
KCTCHS21_RS20805	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS20810	COG1175	transmembrane transport
KCTCHS21_RS20820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCTCHS21_RS20825	COG1309	transcriptional regulator
KCTCHS21_RS20830	COG3437	response regulator, receiver
KCTCHS21_RS20830	COG0784	Response regulator, receiver
KCTCHS21_RS20835	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCTCHS21_RS20840	COG0584	glycerophosphoryl diester phosphodiesterase
KCTCHS21_RS20845	COG2843	Capsule synthesis protein
KCTCHS21_RS20850	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS20855	COG4753	response regulator
KCTCHS21_RS20855	COG2207	Transcriptional regulator
KCTCHS21_RS20860	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS20865	COG1131	(ABC) transporter
KCTCHS21_RS20880	COG0210	DNA helicase
KCTCHS21_RS20900	COG3250	beta-galactosidase activity
KCTCHS21_RS20905	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS20910	COG1175	transmembrane transport
KCTCHS21_RS20915	COG1653	transport
KCTCHS21_RS20920	COG4753	response regulator
KCTCHS21_RS20920	COG4753	response regulator
KCTCHS21_RS20920	COG2207	Transcriptional regulator
KCTCHS21_RS20920	COG2207	Transcriptional regulator
KCTCHS21_RS20925	COG2972	Histidine kinase
KCTCHS21_RS20940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KCTCHS21_RS20945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCTCHS21_RS20950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCTCHS21_RS20965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCTCHS21_RS20970	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS20975	COG0444	Belongs to the ABC transporter superfamily
KCTCHS21_RS20980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS20985	COG0601	transmembrane transport
KCTCHS21_RS20990	COG4166	transmembrane transport
KCTCHS21_RS20995	COG4122	O-methyltransferase activity
KCTCHS21_RS21000	COG1368	sulfuric ester hydrolase activity
KCTCHS21_RS21040	COG2445	Protein of unknown function DUF86
KCTCHS21_RS21065	COG4824	toxin secretion phage lysis holin
KCTCHS21_RS21075	COG1136	(ABC) transporter
KCTCHS21_RS21090	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS21095	COG1175	transmembrane transport
KCTCHS21_RS21105	COG2972	Histidine kinase
KCTCHS21_RS21125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCTCHS21_RS21130	COG1554	hydrolase, family 65, central catalytic
KCTCHS21_RS21140	COG0501	Belongs to the peptidase M48B family
KCTCHS21_RS21145	COG1376	ErfK ybiS ycfS ynhG family protein
KCTCHS21_RS21150	COG0129	dihydroxy-acid dehydratase activity
KCTCHS21_RS21170	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS21210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCTCHS21_RS21220	COG0741	lytic transglycosylase activity
KCTCHS21_RS21220	COG0739	heme binding
KCTCHS21_RS21220	COG1196	nuclear chromosome segregation
KCTCHS21_RS21225	COG0237	dephospho-CoA kinase activity
KCTCHS21_RS21230	COG1971	Probably functions as a manganese efflux pump
KCTCHS21_RS21235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCTCHS21_RS21245	COG2200	EAL domain
KCTCHS21_RS21255	COG0704	Plays a role in the regulation of phosphate uptake
KCTCHS21_RS21260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCTCHS21_RS21265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCTCHS21_RS21270	COG0581	inorganic phosphate transmembrane transporter activity
KCTCHS21_RS21275	COG0573	inorganic phosphate transmembrane transporter activity
KCTCHS21_RS21280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCTCHS21_RS21290	COG0581	inorganic phosphate transmembrane transporter activity
KCTCHS21_RS21295	COG0573	inorganic phosphate transmembrane transporter activity
KCTCHS21_RS21300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCTCHS21_RS21310	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS21310	COG3290	protein histidine kinase activity
KCTCHS21_RS21390	COG2856	Zn peptidase
KCTCHS21_RS21395	COG1396	sequence-specific DNA binding
KCTCHS21_RS21425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCTCHS21_RS21450	COG4974	Belongs to the 'phage' integrase family
KCTCHS21_RS21465	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS21470	COG1082	Xylose isomerase domain protein TIM barrel
KCTCHS21_RS21475	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS21490	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS21495	COG5002	protein histidine kinase activity
KCTCHS21_RS21505	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KCTCHS21_RS21520	COG0039	L-malate dehydrogenase activity
KCTCHS21_RS21525	COG0538	isocitrate dehydrogenase activity
KCTCHS21_RS21530	COG0372	Belongs to the citrate synthase family
KCTCHS21_RS21535	COG0248	Ppx GppA phosphatase
KCTCHS21_RS21540	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KCTCHS21_RS21545	COG3030	protein affecting phage T7 exclusion by the F plasmid
KCTCHS21_RS21550	COG0824	Thioesterase
KCTCHS21_RS21560	COG0825	malonyl-CoA metabolic process
KCTCHS21_RS21565	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCTCHS21_RS21580	COG0587	DNA-directed DNA polymerase activity
KCTCHS21_RS21600	COG4109	DRTGG domain
KCTCHS21_RS21610	COG2197	response regulator
KCTCHS21_RS21620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCTCHS21_RS21630	COG1216	Glycosyl transferase, family 2
KCTCHS21_RS21645	COG1216	Glycosyl transferase, family 2
KCTCHS21_RS21660	COG1086	Polysaccharide biosynthesis protein
KCTCHS21_RS21725	COG1215	transferase activity, transferring glycosyl groups
KCTCHS21_RS21735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCTCHS21_RS21740	COG1216	Glycosyl transferase, family 2
KCTCHS21_RS21740	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS21770	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS21775	COG0688	phosphatidylethanolamine metabolic process
KCTCHS21_RS21785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCTCHS21_RS21790	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KCTCHS21_RS21795	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS21800	COG2188	Transcriptional regulator
KCTCHS21_RS21830	COG1131	(ABC) transporter
KCTCHS21_RS21840	COG0697	spore germination
KCTCHS21_RS21855	COG3266	domain, Protein
KCTCHS21_RS21855	COG2911	Protein conserved in bacteria
KCTCHS21_RS21855	COG1361	Conserved repeat domain
KCTCHS21_RS21865	COG0300	oxidoreductase activity
KCTCHS21_RS21870	COG1406	Chemotaxis phosphatase CheX
KCTCHS21_RS21880	COG2270	Major facilitator Superfamily
KCTCHS21_RS21890	COG2814	Major facilitator Superfamily
KCTCHS21_RS21895	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS21905	COG1741	Belongs to the pirin family
KCTCHS21_RS21910	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS21920	COG1876	peptidase activity
KCTCHS21_RS21925	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS21930	COG5002	protein histidine kinase activity
KCTCHS21_RS21940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KCTCHS21_RS21945	COG1053	succinate dehydrogenase
KCTCHS21_RS21950	COG2009	succinate dehydrogenase
KCTCHS21_RS21955	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS21960	COG1388	LysM domain
KCTCHS21_RS21960	COG3584	3D domain protein
KCTCHS21_RS21970	COG0569	domain protein
KCTCHS21_RS21975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KCTCHS21_RS21990	COG0322	excinuclease ABC activity
KCTCHS21_RS22000	COG5583	Uncharacterized small protein (DUF2292)
KCTCHS21_RS22005	COG4208	sulfate ABC transporter
KCTCHS21_RS22020	COG1484	DNA-dependent DNA replication
KCTCHS21_RS22025	COG3611	Membrane attachment protein
KCTCHS21_RS22035	COG2246	polysaccharide biosynthetic process
KCTCHS21_RS22045	COG3253	May function as heme-dependent peroxidase
KCTCHS21_RS22050	COG2373	Large extracellular alpha-helical protein
KCTCHS21_RS22065	COG1846	Transcriptional regulator
KCTCHS21_RS22070	COG1027	Aspartate ammonia-lyase
KCTCHS21_RS22080	COG1252	NADH dehydrogenase
KCTCHS21_RS22095	COG0189	ligase activity
KCTCHS21_RS22115	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS22120	COG4209	transmembrane transport
KCTCHS21_RS22125	COG1609	Transcriptional regulator
KCTCHS21_RS22135	COG0316	Belongs to the HesB IscA family
KCTCHS21_RS22145	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KCTCHS21_RS22150	COG1252	NADH dehydrogenase
KCTCHS21_RS22155	COG4844	belongs to the
KCTCHS21_RS22160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KCTCHS21_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS22175	COG1612	heme a metabolic process
KCTCHS21_RS22200	COG2839	Protein conserved in bacteria
KCTCHS21_RS22205	COG0561	phosphatase activity
KCTCHS21_RS22240	COG1999	signal sequence binding
KCTCHS21_RS22245	COG0109	protoheme IX farnesyltransferase activity
KCTCHS21_RS22260	COG1988	membrane-bound metal-dependent
KCTCHS21_RS22270	COG0180	Tryptophanyl-tRNA synthetase
KCTCHS21_RS22300	COG2346	COG2346, Truncated hemoglobins
KCTCHS21_RS22310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCTCHS21_RS22315	COG4470	Protein conserved in bacteria
KCTCHS21_RS22320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KCTCHS21_RS22325	COG0739	heme binding
KCTCHS21_RS22350	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS22355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCTCHS21_RS22365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCTCHS21_RS22380	COG2972	Histidine kinase
KCTCHS21_RS22380	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS22390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCTCHS21_RS22420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCTCHS21_RS22425	COG0569	domain protein
KCTCHS21_RS22435	COG3454	Phosphonate metabolism
KCTCHS21_RS22440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCTCHS21_RS22445	COG0477	Major facilitator Superfamily
KCTCHS21_RS22460	COG0789	Transcriptional regulator
KCTCHS21_RS22465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KCTCHS21_RS22470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCTCHS21_RS22480	COG2197	response regulator
KCTCHS21_RS22485	COG4585	Histidine kinase
KCTCHS21_RS22490	COG4758	membrane
KCTCHS21_RS22495	COG1842	Phage shock protein A
KCTCHS21_RS22500	COG1983	PspC domain protein
KCTCHS21_RS22505	COG1842	Phage shock protein A
KCTCHS21_RS22520	COG3842	ATPase activity
KCTCHS21_RS22530	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS22545	COG1131	(ABC) transporter
KCTCHS21_RS22560	COG2207	Transcriptional regulator
KCTCHS21_RS22560	COG4753	response regulator
KCTCHS21_RS22585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCTCHS21_RS22590	COG2207	Transcriptional regulator
KCTCHS21_RS22595	COG2176	DNA-directed DNA polymerase activity
KCTCHS21_RS22610	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS22615	COG3623	hexulose-6-phosphate isomerase
KCTCHS21_RS22635	COG0657	acetylesterase activity
KCTCHS21_RS22640	COG1362	aminopeptidase activity
KCTCHS21_RS22655	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS22660	COG0444	Belongs to the ABC transporter superfamily
KCTCHS21_RS22665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS22670	COG0601	transmembrane transport
KCTCHS21_RS22675	COG0747	negative chemotaxis
KCTCHS21_RS22685	COG5566	PFAM Mor transcription activator
KCTCHS21_RS22700	COG0789	Transcriptional regulator
KCTCHS21_RS22705	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS22710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS22725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS22735	COG0747	negative chemotaxis
KCTCHS21_RS22740	COG1309	transcriptional regulator
KCTCHS21_RS22745	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS22755	COG2207	Transcriptional regulator
KCTCHS21_RS22850	COG2197	response regulator
KCTCHS21_RS22985	COG1285	pathogenesis
KCTCHS21_RS22990	COG0456	acetyltransferase
KCTCHS21_RS22990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCTCHS21_RS22995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCTCHS21_RS23000	COG0154	amidase activity
KCTCHS21_RS23005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCTCHS21_RS23010	COG3300	MHYT domain
KCTCHS21_RS23010	COG5001	Diguanylate cyclase
KCTCHS21_RS23020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KCTCHS21_RS23025	COG1131	(ABC) transporter
KCTCHS21_RS23045	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS23055	COG0667	Aldo Keto reductase
KCTCHS21_RS23060	COG3706	GGDEF domain
KCTCHS21_RS23105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCTCHS21_RS23115	COG0586	Pfam SNARE associated Golgi protein
KCTCHS21_RS23165	COG2267	carboxylic ester hydrolase activity
KCTCHS21_RS23185	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KCTCHS21_RS23190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCTCHS21_RS23195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCTCHS21_RS23210	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS23235	COG1191	sigma factor activity
KCTCHS21_RS23240	COG2172	sigma factor antagonist activity
KCTCHS21_RS23245	COG1366	Belongs to the anti-sigma-factor antagonist family
KCTCHS21_RS23250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCTCHS21_RS23260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KCTCHS21_RS23265	COG5002	protein histidine kinase activity
KCTCHS21_RS23265	COG2205	protein histidine kinase activity
KCTCHS21_RS23265	COG0784	Response regulator, receiver
KCTCHS21_RS23270	COG2208	phosphoserine phosphatase activity
KCTCHS21_RS23280	COG5487	UPF0391 membrane protein
KCTCHS21_RS23285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCTCHS21_RS23305	COG0564	pseudouridine synthase activity
KCTCHS21_RS23320	COG1643	Atp-dependent helicase
KCTCHS21_RS23325	COG4211	Belongs to the binding-protein-dependent transport system permease family
KCTCHS21_RS23340	COG1879	ABC-type sugar transport system periplasmic component
KCTCHS21_RS23345	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS23350	COG4753	response regulator
KCTCHS21_RS23350	COG2207	Transcriptional regulator
KCTCHS21_RS23360	COG1174	glycine betaine transport
KCTCHS21_RS23375	COG1174	glycine betaine transport
KCTCHS21_RS23390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCTCHS21_RS23395	COG2986	histidine ammonia-lyase
KCTCHS21_RS23405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCTCHS21_RS23420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCTCHS21_RS23425	COG1136	(ABC) transporter
KCTCHS21_RS23430	COG1609	Transcriptional regulator
KCTCHS21_RS23435	COG1737	Transcriptional regulator
KCTCHS21_RS23440	COG0363	glucosamine-6-phosphate deaminase activity
KCTCHS21_RS23445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCTCHS21_RS23450	COG0739	heme binding
KCTCHS21_RS23470	COG5002	protein histidine kinase activity
KCTCHS21_RS23475	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS23490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KCTCHS21_RS23510	COG1012	belongs to the aldehyde dehydrogenase family
KCTCHS21_RS23520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS23525	COG1116	anion transmembrane transporter activity
KCTCHS21_RS23530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCTCHS21_RS23545	COG1272	protein, Hemolysin III
KCTCHS21_RS23560	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS23565	COG1801	Protein of unknown function DUF72
KCTCHS21_RS23580	COG2200	EAL domain
KCTCHS21_RS23590	COG0477	Major facilitator Superfamily
KCTCHS21_RS23620	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS23630	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KCTCHS21_RS23635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCTCHS21_RS23640	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KCTCHS21_RS23650	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCTCHS21_RS23655	COG1129	ABC transporter
KCTCHS21_RS23665	COG2972	Histidine kinase
KCTCHS21_RS23670	COG2207	Transcriptional regulator
KCTCHS21_RS23675	COG0567	Dehydrogenase, E1 component
KCTCHS21_RS23680	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCTCHS21_RS23695	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KCTCHS21_RS23700	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KCTCHS21_RS23705	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KCTCHS21_RS23710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KCTCHS21_RS23710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KCTCHS21_RS23730	COG1606	tRNA processing
KCTCHS21_RS23735	COG1691	(AIR) carboxylase
KCTCHS21_RS23740	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KCTCHS21_RS23745	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS23750	COG1175	transmembrane transport
KCTCHS21_RS23760	COG1361	Conserved repeat domain
KCTCHS21_RS23790	COG2207	Transcriptional regulator
KCTCHS21_RS23790	COG4753	response regulator
KCTCHS21_RS23795	COG2972	Histidine kinase
KCTCHS21_RS23810	COG1131	(ABC) transporter
KCTCHS21_RS23815	COG1725	Transcriptional regulator
KCTCHS21_RS23820	COG1940	carbohydrate kinase activity
KCTCHS21_RS23825	COG3706	GGDEF domain
KCTCHS21_RS23825	COG4251	negative regulation of phosphorylation
KCTCHS21_RS23825	COG5001	Diguanylate cyclase
KCTCHS21_RS23825	COG2203	Gaf domain
KCTCHS21_RS23835	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS23845	COG0446	pyridine nucleotide-disulphide oxidoreductase
KCTCHS21_RS23850	COG1234	tRNA 3'-trailer cleavage
KCTCHS21_RS23870	COG0784	Response regulator, receiver
KCTCHS21_RS23870	COG3437	response regulator, receiver
KCTCHS21_RS23900	COG0753	catalase activity
KCTCHS21_RS23910	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS23915	COG1175	transmembrane transport
KCTCHS21_RS23925	COG2207	Transcriptional regulator
KCTCHS21_RS23935	COG4474	Belongs to the UPF0398 family
KCTCHS21_RS23950	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS23955	COG1175	transmembrane transport
KCTCHS21_RS23965	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS23970	COG2207	Transcriptional regulator
KCTCHS21_RS23970	COG4753	response regulator
KCTCHS21_RS23980	COG0095	Lipoate-protein ligase
KCTCHS21_RS23985	COG0084	hydrolase, TatD family'
KCTCHS21_RS24000	COG0326	Molecular chaperone. Has ATPase activity
KCTCHS21_RS24020	COG1122	ATPase activity
KCTCHS21_RS24050	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS24055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCTCHS21_RS24085	COG2076	Multidrug Resistance protein
KCTCHS21_RS24090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KCTCHS21_RS24095	COG1653	transport
KCTCHS21_RS24105	COG1175	transmembrane transport
KCTCHS21_RS24115	COG0456	acetyltransferase
KCTCHS21_RS24120	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS24135	COG1175	transmembrane transport
KCTCHS21_RS24155	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS24155	COG2972	Histidine kinase
KCTCHS21_RS24185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCTCHS21_RS24220	COG0252	asparaginase activity
KCTCHS21_RS24225	COG0252	asparaginase activity
KCTCHS21_RS24245	COG1131	(ABC) transporter
KCTCHS21_RS24255	COG0835	chemotaxis
KCTCHS21_RS24260	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS24265	COG2199	diguanylate cyclase activity
KCTCHS21_RS24265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KCTCHS21_RS24270	COG4974	Belongs to the 'phage' integrase family
KCTCHS21_RS24275	COG2205	protein histidine kinase activity
KCTCHS21_RS24280	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS24315	COG1725	Transcriptional regulator
KCTCHS21_RS24325	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS24330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCTCHS21_RS24340	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KCTCHS21_RS24350	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS24355	COG1175	transmembrane transport
KCTCHS21_RS24360	COG1653	transport
KCTCHS21_RS24365	COG2207	Transcriptional regulator
KCTCHS21_RS24365	COG4753	response regulator
KCTCHS21_RS24370	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS24380	COG1653	transport
KCTCHS21_RS24385	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS24390	COG4209	transmembrane transport
KCTCHS21_RS24400	COG5520	Belongs to the glycosyl hydrolase 30 family
KCTCHS21_RS24410	COG0697	spore germination
KCTCHS21_RS24420	COG1959	2 iron, 2 sulfur cluster binding
KCTCHS21_RS24435	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS24440	COG1132	(ABC) transporter
KCTCHS21_RS24445	COG1132	(ABC) transporter
KCTCHS21_RS24455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS24460	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS24480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS24485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS24490	COG1126	abc transporter atp-binding protein
KCTCHS21_RS24495	COG0765	amino acid transport
KCTCHS21_RS24500	COG0765	amino acid transport
KCTCHS21_RS24505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCTCHS21_RS24510	COG2911	Protein conserved in bacteria
KCTCHS21_RS24510	COG3266	domain, Protein
KCTCHS21_RS24510	COG1361	Conserved repeat domain
KCTCHS21_RS24515	COG0514	ATP-dependent DNA helicase (RecQ)
KCTCHS21_RS24520	COG2207	Transcriptional regulator
KCTCHS21_RS24535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS24545	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS24555	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS24560	COG2972	Histidine kinase
KCTCHS21_RS24560	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS24570	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS24580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS24585	COG0601	transmembrane transport
KCTCHS21_RS24590	COG0747	negative chemotaxis
KCTCHS21_RS24595	COG2368	4-hydroxyphenylacetate
KCTCHS21_RS24610	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS24620	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS24635	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS24640	COG0604	alcohol dehydrogenase
KCTCHS21_RS24660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS24670	COG5002	protein histidine kinase activity
KCTCHS21_RS24705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCTCHS21_RS24715	COG2271	Major facilitator Superfamily
KCTCHS21_RS24725	COG4196	transglutaminase domain protein
KCTCHS21_RS24755	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS24760	COG1175	transmembrane transport
KCTCHS21_RS24775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS24775	COG2207	Transcriptional regulator
KCTCHS21_RS24785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCTCHS21_RS24810	COG2017	converts alpha-aldose to the beta-anomer
KCTCHS21_RS24815	COG1486	melibiose metabolic process
KCTCHS21_RS24820	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS24825	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS24830	COG4209	transmembrane transport
KCTCHS21_RS24835	COG1653	transport
KCTCHS21_RS24840	COG2207	Transcriptional regulator
KCTCHS21_RS24840	COG4753	response regulator
KCTCHS21_RS24845	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS24860	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS24865	COG1175	transmembrane transport
KCTCHS21_RS24880	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS24885	COG1175	transmembrane transport
KCTCHS21_RS24895	COG3842	ATPase activity
KCTCHS21_RS24910	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS24920	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS24930	COG5002	protein histidine kinase activity
KCTCHS21_RS24950	COG1361	Conserved repeat domain
KCTCHS21_RS24975	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS24995	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS25000	COG5002	protein histidine kinase activity
KCTCHS21_RS25020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCTCHS21_RS25040	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS25055	COG2718	Belongs to the UPF0229 family
KCTCHS21_RS25070	COG1696	Membrane protein involved in D-alanine export
KCTCHS21_RS25085	COG0529	Catalyzes the synthesis of activated sulfate
KCTCHS21_RS25100	COG2226	methyltransferase
KCTCHS21_RS25130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCTCHS21_RS25135	COG1597	lipid kinase activity
KCTCHS21_RS25145	COG4496	protein, YerC YecD
KCTCHS21_RS25160	COG0306	phosphate transporter
KCTCHS21_RS25165	COG1392	Phosphate transport regulator
KCTCHS21_RS25170	COG1309	transcriptional regulator
KCTCHS21_RS25175	COG2814	Major facilitator Superfamily
KCTCHS21_RS25180	COG1470	cell adhesion involved in biofilm formation
KCTCHS21_RS25200	COG0151	Belongs to the GarS family
KCTCHS21_RS25205	COG0138	bifunctional purine biosynthesis protein purh
KCTCHS21_RS25210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCTCHS21_RS25215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KCTCHS21_RS25220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCTCHS21_RS25225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCTCHS21_RS25230	COG0047	phosphoribosylformylglycinamidine synthase activity
KCTCHS21_RS25235	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCTCHS21_RS25245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCTCHS21_RS25250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCTCHS21_RS25255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCTCHS21_RS25260	COG2252	PERMEase
KCTCHS21_RS25265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCTCHS21_RS25265	COG0519	Catalyzes the synthesis of GMP from XMP
KCTCHS21_RS25270	COG2223	nitrite transmembrane transporter activity
KCTCHS21_RS25275	COG2186	Transcriptional regulator
KCTCHS21_RS25280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCTCHS21_RS25295	COG4555	ABC transporter
KCTCHS21_RS25305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCTCHS21_RS25310	COG0523	cobalamin synthesis protein
KCTCHS21_RS25315	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCTCHS21_RS25320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCTCHS21_RS25325	COG1121	(ABC) transporter
KCTCHS21_RS25335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCTCHS21_RS25340	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCTCHS21_RS25345	COG3250	beta-galactosidase activity
KCTCHS21_RS25350	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS25355	COG1175	transmembrane transport
KCTCHS21_RS25365	COG4753	response regulator
KCTCHS21_RS25365	COG2207	Transcriptional regulator
KCTCHS21_RS25380	COG0483	inositol monophosphate 1-phosphatase activity
KCTCHS21_RS25405	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCTCHS21_RS25415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCTCHS21_RS25420	COG3480	Lon protease (S16) C-terminal proteolytic domain
KCTCHS21_RS25430	COG1414	Transcriptional regulator
KCTCHS21_RS25440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCTCHS21_RS25445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS25450	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS25455	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS25460	COG0643	Histidine kinase
KCTCHS21_RS25460	COG2198	Histidine kinase
KCTCHS21_RS25465	COG0835	chemotaxis
KCTCHS21_RS25485	COG0302	gtp cyclohydrolase
KCTCHS21_RS25510	COG0456	acetyltransferase
KCTCHS21_RS25515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCTCHS21_RS25520	COG3290	protein histidine kinase activity
KCTCHS21_RS25520	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS25525	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS25530	COG2198	Histidine kinase
KCTCHS21_RS25530	COG0643	Histidine kinase
KCTCHS21_RS25535	COG0835	chemotaxis
KCTCHS21_RS25540	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS25550	COG1194	a g-specific adenine glycosylase
KCTCHS21_RS25560	COG0736	holo-[acyl-carrier-protein] synthase activity
KCTCHS21_RS25565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KCTCHS21_RS25575	COG5002	protein histidine kinase activity
KCTCHS21_RS25580	COG2081	HI0933 family
KCTCHS21_RS25585	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS25590	COG1175	transmembrane transport
KCTCHS21_RS25605	COG1609	Transcriptional regulator
KCTCHS21_RS25625	COG1131	(ABC) transporter
KCTCHS21_RS25630	COG1070	Carbohydrate kinase
KCTCHS21_RS25655	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KCTCHS21_RS25660	COG2207	Transcriptional regulator
KCTCHS21_RS25665	COG2059	Chromate
KCTCHS21_RS25670	COG2059	Chromate
KCTCHS21_RS25675	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS25685	COG0861	Integral membrane protein TerC family
KCTCHS21_RS25690	COG0791	NLP P60 protein
KCTCHS21_RS25695	COG1940	carbohydrate kinase activity
KCTCHS21_RS25710	COG2326	polyphosphate kinase activity
KCTCHS21_RS25735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KCTCHS21_RS25735	COG2199	diguanylate cyclase activity
KCTCHS21_RS25750	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS25755	COG0640	Transcriptional regulator
KCTCHS21_RS25765	COG5520	Belongs to the glycosyl hydrolase 30 family
KCTCHS21_RS25770	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS25775	COG3458	cephalosporin-C deacetylase activity
KCTCHS21_RS25780	COG2318	DinB family
KCTCHS21_RS25790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS25800	COG1120	ATPase activity
KCTCHS21_RS25810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS25815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS25820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS25835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCTCHS21_RS25835	COG1263	PTS System
KCTCHS21_RS25840	COG2190	(PTS) system
KCTCHS21_RS25845	COG3711	transcriptional antiterminator
KCTCHS21_RS25855	COG1175	transmembrane transport
KCTCHS21_RS25860	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS25865	COG1408	metallophosphoesterase
KCTCHS21_RS25880	COG0129	dihydroxy-acid dehydratase activity
KCTCHS21_RS25885	COG2017	converts alpha-aldose to the beta-anomer
KCTCHS21_RS25890	COG1486	melibiose metabolic process
KCTCHS21_RS25895	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS25905	COG1175	transmembrane transport
KCTCHS21_RS25920	COG2172	sigma factor antagonist activity
KCTCHS21_RS25925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KCTCHS21_RS25930	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS25970	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS25975	COG1175	transmembrane transport
KCTCHS21_RS25980	COG1653	transport
KCTCHS21_RS25985	COG1653	transport
KCTCHS21_RS25990	COG2207	Transcriptional regulator
KCTCHS21_RS25990	COG4753	response regulator
KCTCHS21_RS25995	COG2972	Histidine kinase
KCTCHS21_RS26005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCTCHS21_RS26020	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS26060	COG0791	NLP P60 protein
KCTCHS21_RS26065	COG0726	polysaccharide deacetylase
KCTCHS21_RS26070	COG4641	Protein conserved in bacteria
KCTCHS21_RS26070	COG1388	LysM domain
KCTCHS21_RS26080	COG4641	Protein conserved in bacteria
KCTCHS21_RS26080	COG1388	LysM domain
KCTCHS21_RS26090	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS26095	COG0006	proline dipeptidase activity
KCTCHS21_RS26120	COG2207	Transcriptional regulator
KCTCHS21_RS26130	COG1361	Conserved repeat domain
KCTCHS21_RS26140	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS26145	COG4209	transmembrane transport
KCTCHS21_RS26150	COG2972	Histidine kinase
KCTCHS21_RS26155	COG4753	response regulator
KCTCHS21_RS26155	COG2207	Transcriptional regulator
KCTCHS21_RS26170	COG2182	Extracellular solute-binding protein
KCTCHS21_RS26185	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS26190	COG4753	response regulator
KCTCHS21_RS26190	COG2207	Transcriptional regulator
KCTCHS21_RS26195	COG0697	spore germination
KCTCHS21_RS26200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS26215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS26220	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS26225	COG0444	Belongs to the ABC transporter superfamily
KCTCHS21_RS26250	COG1053	succinate dehydrogenase
KCTCHS21_RS26260	COG3250	beta-galactosidase activity
KCTCHS21_RS26265	COG2207	Transcriptional regulator
KCTCHS21_RS26275	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS26280	COG4209	transmembrane transport
KCTCHS21_RS26285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KCTCHS21_RS26295	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS26305	COG0613	PHP domain protein
KCTCHS21_RS26310	COG3454	Phosphonate metabolism
KCTCHS21_RS26315	COG4778	phosphonate C-P lyase system protein PhnL
KCTCHS21_RS26320	COG4107	phosphonate C-P lyase system protein PhnK
KCTCHS21_RS26325	COG3627	carbon phosphorus lyase activity
KCTCHS21_RS26345	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS26355	COG3842	ATPase activity
KCTCHS21_RS26380	COG3773	Cell wall hydrolase
KCTCHS21_RS26390	COG0110	maltose O-acetyltransferase activity
KCTCHS21_RS26395	COG0110	maltose O-acetyltransferase activity
KCTCHS21_RS26405	COG2207	Transcriptional regulator
KCTCHS21_RS26410	COG1349	DNA-binding transcription factor activity
KCTCHS21_RS26420	COG4106	trans-aconitate 2-methyltransferase activity
KCTCHS21_RS26425	COG2267	carboxylic ester hydrolase activity
KCTCHS21_RS26430	COG0156	8-amino-7-oxononanoate synthase activity
KCTCHS21_RS26435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCTCHS21_RS26445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCTCHS21_RS26475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCTCHS21_RS26510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCTCHS21_RS26515	COG0601	transmembrane transport
KCTCHS21_RS26520	COG4608	Belongs to the ABC transporter superfamily
KCTCHS21_RS26525	COG0444	Belongs to the ABC transporter superfamily
KCTCHS21_RS26530	COG0747	negative chemotaxis
KCTCHS21_RS26535	COG2146	nitrite reductase [NAD(P)H] activity
KCTCHS21_RS26580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCTCHS21_RS26585	COG4856	YbbR-like protein
KCTCHS21_RS26590	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCTCHS21_RS26595	COG5662	AntiSigma factor
KCTCHS21_RS26600	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS26605	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KCTCHS21_RS26640	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS26660	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS26735	COG0726	polysaccharide deacetylase
KCTCHS21_RS26750	COG0489	protein tyrosine kinase activity
KCTCHS21_RS26755	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS26760	COG2046	Belongs to the sulfate adenylyltransferase family
KCTCHS21_RS26765	COG0175	sulfate reduction
KCTCHS21_RS26770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KCTCHS21_RS26775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCTCHS21_RS26780	COG0101	tRNA pseudouridine synthase activity
KCTCHS21_RS26785	COG0203	ribosomal protein L17
KCTCHS21_RS26790	COG0202	RNA polymerase activity
KCTCHS21_RS26795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCTCHS21_RS26800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCTCHS21_RS26805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KCTCHS21_RS26810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCTCHS21_RS26815	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KCTCHS21_RS26820	COG0024	Methionine aminopeptidase
KCTCHS21_RS26825	COG0563	adenylate kinase activity
KCTCHS21_RS26830	COG0201	protein transport
KCTCHS21_RS26835	COG0200	Binds to the 23S rRNA
KCTCHS21_RS26840	COG1841	ribosomal large subunit assembly
KCTCHS21_RS26845	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCTCHS21_RS26850	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCTCHS21_RS26855	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCTCHS21_RS26860	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCTCHS21_RS26870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCTCHS21_RS26875	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCTCHS21_RS26880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCTCHS21_RS26885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCTCHS21_RS26890	COG0255	Belongs to the universal ribosomal protein uL29 family
KCTCHS21_RS26895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCTCHS21_RS26900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCTCHS21_RS26910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCTCHS21_RS26915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCTCHS21_RS26920	COG0089	rRNA binding
KCTCHS21_RS26925	COG0088	Forms part of the polypeptide exit tunnel
KCTCHS21_RS26930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCTCHS21_RS26945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCTCHS21_RS26955	COG2323	membrane
KCTCHS21_RS26965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS26975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCTCHS21_RS26980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCTCHS21_RS26985	COG0049	tRNA binding
KCTCHS21_RS26990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCTCHS21_RS27000	COG1131	(ABC) transporter
KCTCHS21_RS27005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCTCHS21_RS27010	COG0085	RNA polymerase activity
KCTCHS21_RS27015	COG2813	Specifically methylates the guanine in position
KCTCHS21_RS27020	COG0222	ribosome binding
KCTCHS21_RS27025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCTCHS21_RS27030	COG0081	regulation of translation
KCTCHS21_RS27035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCTCHS21_RS27040	COG0250	Participates in transcription elongation, termination and antitermination
KCTCHS21_RS27045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCTCHS21_RS27050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KCTCHS21_RS27060	COG3688	RNA-binding protein containing a PIN domain
KCTCHS21_RS27065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCTCHS21_RS27070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCTCHS21_RS27075	COG0215	cysteine-tRNA ligase activity
KCTCHS21_RS27080	COG1045	serine acetyltransferase
KCTCHS21_RS27085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCTCHS21_RS27090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCTCHS21_RS27095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KCTCHS21_RS27100	COG4956	integral membrane protein (PIN domain superfamily)
KCTCHS21_RS27110	COG1183	phosphatidylcholine synthase activity
KCTCHS21_RS27115	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KCTCHS21_RS27120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCTCHS21_RS27125	COG0542	response to heat
KCTCHS21_RS27130	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KCTCHS21_RS27135	COG3880	PFAM UvrB UvrC protein
KCTCHS21_RS27185	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS27210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCTCHS21_RS27220	COG0210	DNA helicase
KCTCHS21_RS27225	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KCTCHS21_RS27235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCTCHS21_RS27245	COG0826	peptidase U32
KCTCHS21_RS27255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCTCHS21_RS27270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCTCHS21_RS27280	COG0556	nucleotide-excision repair
KCTCHS21_RS27295	COG2076	Multidrug Resistance protein
KCTCHS21_RS27300	COG2076	Multidrug Resistance protein
KCTCHS21_RS27305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCTCHS21_RS27310	COG3409	Peptidoglycan-binding domain 1 protein
KCTCHS21_RS27310	COG0793	Belongs to the peptidase S41A family
KCTCHS21_RS27315	COG0739	heme binding
KCTCHS21_RS27315	COG0741	lytic transglycosylase activity
KCTCHS21_RS27315	COG1196	nuclear chromosome segregation
KCTCHS21_RS27320	COG1196	nuclear chromosome segregation
KCTCHS21_RS27320	COG0741	lytic transglycosylase activity
KCTCHS21_RS27320	COG0739	heme binding
KCTCHS21_RS27325	COG2177	Part of the ABC transporter FtsEX involved in
KCTCHS21_RS27330	COG2884	Cell division ATP-binding protein ftsE
KCTCHS21_RS27335	COG2720	vancomycin resistance protein
KCTCHS21_RS27340	COG0165	Argininosuccinate lyase
KCTCHS21_RS27345	COG0137	argininosuccinate synthase activity
KCTCHS21_RS27350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCTCHS21_RS27360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KCTCHS21_RS27365	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCTCHS21_RS27370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCTCHS21_RS27375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCTCHS21_RS27380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCTCHS21_RS27385	COG0653	protein targeting
KCTCHS21_RS27395	COG1278	Cold shock
KCTCHS21_RS27410	COG3958	Transketolase
KCTCHS21_RS27415	COG3959	Transketolase, thiamine diphosphate binding domain
KCTCHS21_RS27440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCTCHS21_RS27455	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS27455	COG0457	Tetratricopeptide repeat
KCTCHS21_RS27460	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS27470	COG1516	flagellar protein fliS
KCTCHS21_RS27480	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS27480	COG0457	Tetratricopeptide repeat
KCTCHS21_RS27485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCTCHS21_RS27490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCTCHS21_RS27495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCTCHS21_RS27500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCTCHS21_RS27505	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KCTCHS21_RS27515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCTCHS21_RS27520	COG1256	bacterial-type flagellum assembly
KCTCHS21_RS27520	COG4786	Flagellar basal body rod
KCTCHS21_RS27545	COG1040	competence protein
KCTCHS21_RS27550	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCTCHS21_RS27565	COG2197	response regulator
KCTCHS21_RS27570	COG4585	Histidine kinase
KCTCHS21_RS27580	COG2315	Protein conserved in bacteria
KCTCHS21_RS27590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCTCHS21_RS27600	COG1091	dTDP-4-dehydrorhamnose reductase activity
KCTCHS21_RS27615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCTCHS21_RS27630	COG0463	Glycosyl transferase, family 2
KCTCHS21_RS27635	COG0438	transferase activity, transferring glycosyl groups
KCTCHS21_RS27640	COG1215	transferase activity, transferring glycosyl groups
KCTCHS21_RS27665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCTCHS21_RS27695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KCTCHS21_RS27715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCTCHS21_RS27735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCTCHS21_RS27740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCTCHS21_RS27755	COG4786	Flagellar basal body rod
KCTCHS21_RS27760	COG4786	Flagellar basal body rod
KCTCHS21_RS27770	COG1609	Transcriptional regulator
KCTCHS21_RS27775	COG0739	heme binding
KCTCHS21_RS27780	COG2385	sporulation resulting in formation of a cellular spore
KCTCHS21_RS27785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCTCHS21_RS27800	COG1007	ATP synthesis coupled electron transport
KCTCHS21_RS27805	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCTCHS21_RS27810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCTCHS21_RS27820	COG0839	Belongs to the complex I subunit 6 family
KCTCHS21_RS27825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCTCHS21_RS27830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KCTCHS21_RS27835	COG0649	NAD binding
KCTCHS21_RS27840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCTCHS21_RS27845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCTCHS21_RS27850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCTCHS21_RS27855	COG0783	Belongs to the Dps family
KCTCHS21_RS27875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KCTCHS21_RS27880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCTCHS21_RS27885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCTCHS21_RS27890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCTCHS21_RS27900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCTCHS21_RS27910	COG0356	it plays a direct role in the translocation of protons across the membrane
KCTCHS21_RS27925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KCTCHS21_RS27930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCTCHS21_RS27935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCTCHS21_RS27940	COG4475	Protein of unknown function (DUF436)
KCTCHS21_RS27950	COG1971	Probably functions as a manganese efflux pump
KCTCHS21_RS27955	COG0009	L-threonylcarbamoyladenylate synthase
KCTCHS21_RS27970	COG2890	protein-(glutamine-N5) methyltransferase activity
KCTCHS21_RS27975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCTCHS21_RS27985	COG0012	GTP binding
KCTCHS21_RS28000	COG1511	domain protein
KCTCHS21_RS28005	COG1309	transcriptional regulator
KCTCHS21_RS28010	COG3118	belongs to the thioredoxin family
KCTCHS21_RS28020	COG0656	L-ascorbic acid biosynthetic process
KCTCHS21_RS28030	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS28055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCTCHS21_RS28070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCTCHS21_RS28075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCTCHS21_RS28095	COG1131	(ABC) transporter
KCTCHS21_RS28100	COG1725	Transcriptional regulator
KCTCHS21_RS28115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCTCHS21_RS28140	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS28145	COG1175	transmembrane transport
KCTCHS21_RS28155	COG2188	Transcriptional regulator
KCTCHS21_RS28165	COG1473	amidohydrolase
KCTCHS21_RS28170	COG1760	l-serine dehydratase
KCTCHS21_RS28175	COG1760	l-serine dehydratase
KCTCHS21_RS28220	COG2201	protein-glutamate methylesterase activity
KCTCHS21_RS28230	COG0643	Histidine kinase
KCTCHS21_RS28230	COG0784	Response regulator, receiver
KCTCHS21_RS28230	COG2198	Histidine kinase
KCTCHS21_RS28235	COG0242	peptide deformylase activity
KCTCHS21_RS28245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCTCHS21_RS28245	COG1199	ATP-dependent helicase activity
KCTCHS21_RS28250	COG1486	melibiose metabolic process
KCTCHS21_RS28265	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS28270	COG1175	transmembrane transport
KCTCHS21_RS28280	COG1609	Transcriptional regulator
KCTCHS21_RS28285	COG0501	Belongs to the peptidase M48B family
KCTCHS21_RS28300	COG1368	sulfuric ester hydrolase activity
KCTCHS21_RS28315	COG0488	(ABC) transporter
KCTCHS21_RS28320	COG0697	spore germination
KCTCHS21_RS28325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS28335	COG0583	DNA-binding transcription factor activity
KCTCHS21_RS28340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCTCHS21_RS28350	COG2318	DinB family
KCTCHS21_RS28360	COG0640	Transcriptional regulator
KCTCHS21_RS28375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCTCHS21_RS28380	COG0400	carboxylic ester hydrolase activity
KCTCHS21_RS28390	COG1846	Transcriptional regulator
KCTCHS21_RS28395	COG0783	Belongs to the Dps family
KCTCHS21_RS28400	COG0006	proline dipeptidase activity
KCTCHS21_RS28405	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCTCHS21_RS28410	COG1129	ABC transporter
KCTCHS21_RS28445	COG2195	Cleaves the N-terminal amino acid of tripeptides
KCTCHS21_RS28460	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS28465	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS28470	COG1175	transmembrane transport
KCTCHS21_RS28485	COG2207	Transcriptional regulator
KCTCHS21_RS28490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCTCHS21_RS28520	COG2211	Major facilitator Superfamily
KCTCHS21_RS28525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCTCHS21_RS28535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS28550	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS28560	COG4209	transmembrane transport
KCTCHS21_RS28575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCTCHS21_RS28585	COG0246	Mannitol dehydrogenase
KCTCHS21_RS28595	COG3711	transcriptional antiterminator
KCTCHS21_RS28605	COG4912	Dna alkylation repair
KCTCHS21_RS28620	COG0697	spore germination
KCTCHS21_RS28625	COG1979	alcohol dehydrogenase
KCTCHS21_RS28630	COG2814	Major facilitator Superfamily
KCTCHS21_RS28635	COG0095	Lipoate-protein ligase
KCTCHS21_RS28640	COG3290	protein histidine kinase activity
KCTCHS21_RS28640	COG0840	transmembrane signaling receptor activity
KCTCHS21_RS28645	COG1132	(ABC) transporter
KCTCHS21_RS28650	COG1132	(ABC) transporter
KCTCHS21_RS28680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCTCHS21_RS28680	COG3153	acetyltransferase
KCTCHS21_RS28685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCTCHS21_RS28685	COG3153	acetyltransferase
KCTCHS21_RS28690	COG0789	Transcriptional regulator
KCTCHS21_RS28705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCTCHS21_RS28710	COG3706	GGDEF domain
KCTCHS21_RS28725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCTCHS21_RS28745	COG2340	Cysteine-rich secretory protein family
KCTCHS21_RS28755	COG3964	amidohydrolase
KCTCHS21_RS28775	COG2188	Transcriptional regulator
KCTCHS21_RS28785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCTCHS21_RS28790	COG1309	transcriptional regulator
KCTCHS21_RS28795	COG0477	Major facilitator Superfamily
KCTCHS21_RS28805	COG0626	cystathionine gamma-synthase activity
KCTCHS21_RS28810	COG2188	Transcriptional regulator
KCTCHS21_RS28815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCTCHS21_RS28820	COG2197	response regulator
KCTCHS21_RS28830	COG0667	Aldo Keto reductase
KCTCHS21_RS28835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KCTCHS21_RS28840	COG2205	protein histidine kinase activity
KCTCHS21_RS28855	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCTCHS21_RS28875	COG1079	Belongs to the binding-protein-dependent transport system permease family
KCTCHS21_RS28880	COG4603	Belongs to the binding-protein-dependent transport system permease family
KCTCHS21_RS28885	COG3845	ABC transporter
KCTCHS21_RS28890	COG1744	ABC transporter substrate-binding protein PnrA-like
KCTCHS21_RS28895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCTCHS21_RS28905	COG0322	excinuclease ABC activity
KCTCHS21_RS28910	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS28920	COG0477	Major facilitator Superfamily
KCTCHS21_RS28925	COG1051	belongs to the nudix hydrolase family
KCTCHS21_RS28930	COG2207	Transcriptional regulator
KCTCHS21_RS28930	COG3708	Transcriptional regulator
KCTCHS21_RS28935	COG2378	regulation of single-species biofilm formation
KCTCHS21_RS28940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCTCHS21_RS28945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCTCHS21_RS28955	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KCTCHS21_RS28970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS28975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS28980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS28985	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS29005	COG4948	Mandelate Racemase Muconate Lactonizing
KCTCHS21_RS29010	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29025	COG2186	Transcriptional regulator
KCTCHS21_RS29030	COG1733	regulation of RNA biosynthetic process
KCTCHS21_RS29035	COG2814	Major facilitator Superfamily
KCTCHS21_RS29040	COG0656	L-ascorbic acid biosynthetic process
KCTCHS21_RS29045	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS29050	COG5002	protein histidine kinase activity
KCTCHS21_RS29070	COG2824	Alkylphosphonate utilization operon protein PhnA
KCTCHS21_RS29085	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS29090	COG2205	protein histidine kinase activity
KCTCHS21_RS29110	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS29115	COG5002	protein histidine kinase activity
KCTCHS21_RS29130	COG2971	BadF BadG BcrA BcrD
KCTCHS21_RS29135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KCTCHS21_RS29145	COG1175	transmembrane transport
KCTCHS21_RS29150	COG2182	Extracellular solute-binding protein
KCTCHS21_RS29155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KCTCHS21_RS29160	COG1737	Transcriptional regulator
KCTCHS21_RS29190	COG2972	Histidine kinase
KCTCHS21_RS29195	COG4753	response regulator
KCTCHS21_RS29195	COG2207	Transcriptional regulator
KCTCHS21_RS29205	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29210	COG4209	transmembrane transport
KCTCHS21_RS29220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS29225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCTCHS21_RS29230	COG3408	Glycogen debranching enzyme
KCTCHS21_RS29230	COG3119	arylsulfatase activity
KCTCHS21_RS29235	COG1653	transport
KCTCHS21_RS29240	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29245	COG4209	transmembrane transport
KCTCHS21_RS29255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCTCHS21_RS29265	COG4989	oxidoreductase activity
KCTCHS21_RS29280	COG5002	protein histidine kinase activity
KCTCHS21_RS29290	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS29295	COG1609	Transcriptional regulator
KCTCHS21_RS29300	COG1472	Belongs to the glycosyl hydrolase 3 family
KCTCHS21_RS29305	COG3250	beta-galactosidase activity
KCTCHS21_RS29310	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29315	COG1175	transmembrane transport
KCTCHS21_RS29320	COG1653	transport
KCTCHS21_RS29325	COG4753	response regulator
KCTCHS21_RS29325	COG2207	Transcriptional regulator
KCTCHS21_RS29330	COG2972	Histidine kinase
KCTCHS21_RS29340	COG3616	Alanine racemase, N-terminal domain
KCTCHS21_RS29360	COG1028	Short-chain dehydrogenase reductase Sdr
KCTCHS21_RS29365	COG0251	oxidation-reduction process
KCTCHS21_RS29370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCTCHS21_RS29375	COG1653	transport
KCTCHS21_RS29380	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29385	COG4209	transmembrane transport
KCTCHS21_RS29390	COG2207	Transcriptional regulator
KCTCHS21_RS29395	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS29400	COG0006	proline dipeptidase activity
KCTCHS21_RS29425	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29430	COG4209	transmembrane transport
KCTCHS21_RS29435	COG1653	transport
KCTCHS21_RS29440	COG2207	Transcriptional regulator
KCTCHS21_RS29450	COG0805	protein transport
KCTCHS21_RS29455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCTCHS21_RS29465	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS29470	COG2169	Transcriptional regulator
KCTCHS21_RS29475	COG0596	Alpha beta hydrolase
KCTCHS21_RS29480	COG4592	Periplasmic binding protein
KCTCHS21_RS29485	COG2207	Transcriptional regulator
KCTCHS21_RS29490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS29495	COG1653	transport
KCTCHS21_RS29500	COG1175	transmembrane transport
KCTCHS21_RS29505	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29510	COG1595	DNA-templated transcription, initiation
KCTCHS21_RS29530	COG2205	protein histidine kinase activity
KCTCHS21_RS29545	COG0579	oxidoreductase
KCTCHS21_RS29555	COG1522	sequence-specific DNA binding
KCTCHS21_RS29570	COG3250	beta-galactosidase activity
KCTCHS21_RS29580	COG1653	transport
KCTCHS21_RS29585	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29590	COG4209	transmembrane transport
KCTCHS21_RS29595	COG2207	Transcriptional regulator
KCTCHS21_RS29595	COG1609	Transcriptional regulator
KCTCHS21_RS29615	COG0673	inositol 2-dehydrogenase activity
KCTCHS21_RS29620	COG1361	Conserved repeat domain
KCTCHS21_RS29625	COG0697	spore germination
KCTCHS21_RS29665	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29670	COG4209	transmembrane transport
KCTCHS21_RS29680	COG4989	oxidoreductase activity
KCTCHS21_RS29685	COG2207	Transcriptional regulator
KCTCHS21_RS29690	COG2972	Histidine kinase
KCTCHS21_RS29700	COG1175	transmembrane transport
KCTCHS21_RS29705	COG3833	ABC-type maltose transport systems, permease component
KCTCHS21_RS29710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCTCHS21_RS29715	COG0706	membrane insertase activity
KCTCHS21_RS29720	COG2204	response regulator
KCTCHS21_RS29725	COG3275	phosphorelay sensor kinase activity
KCTCHS21_RS29735	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS29740	COG4209	transmembrane transport
KCTCHS21_RS29750	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS29755	COG5002	protein histidine kinase activity
KCTCHS21_RS29760	COG2205	protein histidine kinase activity
KCTCHS21_RS29780	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KCTCHS21_RS29785	COG1361	Conserved repeat domain
KCTCHS21_RS29800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCTCHS21_RS29805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS29810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS29815	COG1116	anion transmembrane transporter activity
KCTCHS21_RS29830	COG2197	response regulator
KCTCHS21_RS29840	COG2205	protein histidine kinase activity
KCTCHS21_RS29855	COG0778	Nitroreductase
KCTCHS21_RS29865	COG3973	AAA domain
KCTCHS21_RS29895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCTCHS21_RS29900	COG0747	negative chemotaxis
KCTCHS21_RS29930	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KCTCHS21_RS29935	COG2205	protein histidine kinase activity
KCTCHS21_RS29940	COG3279	Response regulator of the LytR AlgR family
KCTCHS21_RS29950	COG1917	Cupin 2, conserved barrel domain protein
KCTCHS21_RS29950	COG2207	Transcriptional regulator
KCTCHS21_RS29980	COG1175	transmembrane transport
KCTCHS21_RS30015	COG0789	Transcriptional regulator
KCTCHS21_RS30050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS30055	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCTCHS21_RS30060	COG1120	ATPase activity
KCTCHS21_RS30075	COG3693	PFAM glycoside hydrolase, family 10
KCTCHS21_RS30120	COG3119	arylsulfatase activity
KCTCHS21_RS30135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCTCHS21_RS30145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCTCHS21_RS30160	COG0586	Pfam SNARE associated Golgi protein
KCTCHS21_RS30170	COG2197	response regulator
KCTCHS21_RS30195	COG0488	(ABC) transporter
KCTCHS21_RS30215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCTCHS21_RS30220	COG2059	Chromate
KCTCHS21_RS30230	COG3119	arylsulfatase activity
KCTCHS21_RS30245	COG0395	ABC-type sugar transport system, permease component
KCTCHS21_RS30250	COG4209	transmembrane transport
KCTCHS21_RS30260	COG2207	Transcriptional regulator
KCTCHS21_RS30260	COG4753	response regulator
KCTCHS21_RS30265	COG2972	Histidine kinase
KCTCHS21_RS30270	COG3119	arylsulfatase activity
KCTCHS21_RS30275	COG1361	Conserved repeat domain
KCTCHS21_RS30285	COG0768	penicillin binding
KCTCHS21_RS30290	COG1396	sequence-specific DNA binding
KCTCHS21_RS30295	COG2807	transmembrane transport
KCTCHS21_RS30325	COG5002	protein histidine kinase activity
KCTCHS21_RS30335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCTCHS21_RS30340	COG0785	Cytochrome C biogenesis protein
KCTCHS21_RS30350	COG1361	Conserved repeat domain
KCTCHS21_RS30355	COG1404	Belongs to the peptidase S8 family
KCTCHS21_RS30360	COG0300	oxidoreductase activity
KCTCHS21_RS30395	COG1361	Conserved repeat domain
KCTCHS21_RS30395	COG2911	Protein conserved in bacteria
KCTCHS21_RS30395	COG3266	domain, Protein
KCTCHS21_RS30415	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCTCHS21_RS30420	COG4895	conserved protein (DUF2196)
KCTCHS21_RS30450	COG1070	Carbohydrate kinase
KCTCHS21_RS30460	COG1132	(ABC) transporter
KCTCHS21_RS30465	COG1132	(ABC) transporter
KCTCHS21_RS30480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCTCHS21_RS30490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KCTCHS21_RS30505	COG5002	protein histidine kinase activity
KCTCHS21_RS30510	COG0745	RESPONSE REGULATOR receiver
KCTCHS21_RS30515	COG0739	heme binding
KCTCHS21_RS30515	COG0741	lytic transglycosylase activity
KCTCHS21_RS30515	COG1196	nuclear chromosome segregation
KCTCHS21_RS30525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCTCHS21_RS30530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCTCHS21_RS30535	COG0305	Participates in initiation and elongation during chromosome replication
KCTCHS21_RS30540	COG0359	binds to the 23S rRNA
KCTCHS21_RS30545	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KCTCHS21_RS30555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCTCHS21_RS30565	COG1316	TRANSCRIPTIONal
KCTCHS21_RS30580	COG0629	single-stranded DNA binding
KCTCHS21_RS30585	COG0360	Binds together with S18 to 16S ribosomal RNA
KCTCHS21_RS30595	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCTCHS21_RS30615	COG4481	Protein conserved in bacteria
KCTCHS21_RS30620	COG0668	transmembrane transport
KCTCHS21_RS30640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCTCHS21_RS30645	COG1475	DNA binding
KCTCHS21_RS30650	COG1192	Involved in chromosome partitioning
KCTCHS21_RS30655	COG1475	DNA binding
KCTCHS21_RS30660	COG0357	Ribosomal RNA small subunit methyltransferase G
KCTCHS21_RS30665	COG0445	tRNA wobble uridine modification
KCTCHS21_RS30670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCTCHS21_RS30675	COG1847	R3H domain protein
KCTCHS21_RS30685	COG0594	ribonuclease P activity
KCTCHS21_RS30690	COG0230	Belongs to the bacterial ribosomal protein bL34 family