locus-tag	class	description
GQS55_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GQS55_RS00020	COG0187	DNA topoisomerase II activity
GQS55_RS00025	COG0752	glycyl-tRNA synthetase alpha subunit
GQS55_RS00030	COG0751	glycine-tRNA ligase activity
GQS55_RS00045	COG0425	Belongs to the sulfur carrier protein TusA family
GQS55_RS00055	COG0006	proline dipeptidase activity
GQS55_RS00060	COG1739	Uncharacterized protein family UPF0029
GQS55_RS00065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQS55_RS00070	COG0569	domain protein
GQS55_RS00075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS55_RS00075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS55_RS00095	COG0758	DNA mediated transformation
GQS55_RS00100	COG2922	Belongs to the Smg family
GQS55_RS00105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQS55_RS00110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GQS55_RS00115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQS55_RS00130	COG3047	cAMP biosynthetic process
GQS55_RS00145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GQS55_RS00185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS55_RS00190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQS55_RS00195	COG0805	protein transport
GQS55_RS00205	COG0084	hydrolase, TatD family'
GQS55_RS00210	COG0745	RESPONSE REGULATOR receiver
GQS55_RS00210	COG3706	GGDEF domain
GQS55_RS00225	COG0513	Belongs to the DEAD box helicase family
GQS55_RS00230	COG3118	belongs to the thioredoxin family
GQS55_RS00235	COG1253	flavin adenine dinucleotide binding
GQS55_RS00240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GQS55_RS00250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GQS55_RS00260	COG4771	TonB-dependent receptor
GQS55_RS00280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQS55_RS00300	COG0181	hydroxymethylbilane synthase activity
GQS55_RS00305	COG1965	Belongs to the frataxin family
GQS55_RS00315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQS55_RS00325	COG1011	Hydrolase
GQS55_RS00330	COG0210	DNA helicase
GQS55_RS00335	COG3706	GGDEF domain
GQS55_RS00380	COG2885	chlorophyll binding
GQS55_RS00380	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQS55_RS00420	COG0582	viral genome integration into host DNA
GQS55_RS00480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS55_RS00490	COG2204	response regulator
GQS55_RS00495	COG3267	Type II secretory pathway component ExeA
GQS55_RS00495	COG3409	Peptidoglycan-binding domain 1 protein
GQS55_RS00505	COG0489	protein tyrosine kinase activity
GQS55_RS00520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQS55_RS00525	COG0726	polysaccharide deacetylase
GQS55_RS00540	COG1045	serine acetyltransferase
GQS55_RS00550	COG0726	polysaccharide deacetylase
GQS55_RS00555	COG0438	transferase activity, transferring glycosyl groups
GQS55_RS00595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GQS55_RS00610	COG1215	transferase activity, transferring glycosyl groups
GQS55_RS00620	COG0297	glycogen (starch) synthase activity
GQS55_RS00625	COG0438	transferase activity, transferring glycosyl groups
GQS55_RS00655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GQS55_RS00665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS55_RS00680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS55_RS00685	COG2861	carbohydrate metabolic process
GQS55_RS00690	COG4942	peptidase
GQS55_RS00695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQS55_RS00705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GQS55_RS00710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GQS55_RS00715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQS55_RS00720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GQS55_RS00725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GQS55_RS00730	COG2267	carboxylic ester hydrolase activity
GQS55_RS00740	COG0210	DNA helicase
GQS55_RS00765	COG2133	pyrroloquinoline quinone binding
GQS55_RS00780	COG0601	transmembrane transport
GQS55_RS00785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS55_RS00790	COG0444	Belongs to the ABC transporter superfamily
GQS55_RS00795	COG4608	Belongs to the ABC transporter superfamily
GQS55_RS00800	COG0747	negative chemotaxis
GQS55_RS00805	COG2226	methyltransferase
GQS55_RS00815	COG0625	glutathione transferase activity
GQS55_RS00825	COG2194	sulfuric ester hydrolase activity
GQS55_RS00830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GQS55_RS00840	COG5002	protein histidine kinase activity
GQS55_RS00850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQS55_RS00860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQS55_RS00875	COG2995	paraquat-inducible protein a
GQS55_RS00880	COG3008	intermembrane lipid transfer
GQS55_RS00890	COG2022	thiamine diphosphate biosynthetic process
GQS55_RS00905	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQS55_RS00930	COG4191	Histidine kinase
GQS55_RS00930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQS55_RS00945	COG0129	dihydroxy-acid dehydratase activity
GQS55_RS00950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQS55_RS00965	COG0606	chelatase, subunit chli
GQS55_RS00970	COG0583	DNA-binding transcription factor activity
GQS55_RS00975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GQS55_RS00980	COG3123	guanosine phosphorylase activity
GQS55_RS00985	COG0730	response to heat
GQS55_RS01015	COG0443	Heat shock 70 kDa protein
GQS55_RS01025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GQS55_RS01030	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQS55_RS01035	COG0204	Acyl-transferase
GQS55_RS01040	COG0668	transmembrane transport
GQS55_RS01045	COG0450	alkyl hydroperoxide reductase
GQS55_RS01050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GQS55_RS01060	COG0450	alkyl hydroperoxide reductase
GQS55_RS01065	COG0753	catalase activity
GQS55_RS01085	COG1946	Acyl-CoA thioesterase
GQS55_RS01105	COG1683	Conserved Protein
GQS55_RS01120	COG0514	ATP-dependent DNA helicase (RecQ)
GQS55_RS01125	COG2050	protein possibly involved in aromatic compounds catabolism
GQS55_RS01130	COG2962	Rard protein
GQS55_RS01135	COG0629	single-stranded DNA binding
GQS55_RS01145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQS55_RS01165	COG0402	S-adenosylhomocysteine deaminase activity
GQS55_RS01190	COG1815	bacterial-type flagellum-dependent cell motility
GQS55_RS01195	COG1558	bacterial-type flagellum-dependent cell motility
GQS55_RS01205	COG1749	Flagellar hook protein flgE
GQS55_RS01210	COG4787	bacterial-type flagellum-dependent cell motility
GQS55_RS01215	COG4786	Flagellar basal body rod
GQS55_RS01225	COG1706	bacterial-type flagellum-dependent cell motility
GQS55_RS01235	COG1256	bacterial-type flagellum assembly
GQS55_RS01250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GQS55_RS01255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GQS55_RS01280	COG1191	sigma factor activity
GQS55_RS01285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQS55_RS01290	COG1360	Flagellar Motor Protein
GQS55_RS01315	COG1987	bacterial-type flagellum assembly
GQS55_RS01320	COG1684	flagellar biosynthetic protein fliR
GQS55_RS01335	COG2885	chlorophyll binding
GQS55_RS01340	COG2204	response regulator
GQS55_RS01345	COG1677	Flagellar hook-basal body complex protein FliE
GQS55_RS01380	COG0246	Mannitol dehydrogenase
GQS55_RS01385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS55_RS01390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQS55_RS01400	COG0166	Belongs to the GPI family
GQS55_RS01405	COG1643	Atp-dependent helicase
GQS55_RS01415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQS55_RS01440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQS55_RS01445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQS55_RS01470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS55_RS01490	COG3118	belongs to the thioredoxin family
GQS55_RS01495	COG0583	DNA-binding transcription factor activity
GQS55_RS01525	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS01530	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS01560	COG0339	signal peptide processing
GQS55_RS01575	COG0456	acetyltransferase
GQS55_RS01585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS55_RS01590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQS55_RS01595	COG2986	histidine ammonia-lyase
GQS55_RS01600	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GQS55_RS01605	COG2188	Transcriptional regulator
GQS55_RS01620	COG2203	Gaf domain
GQS55_RS01620	COG3706	GGDEF domain
GQS55_RS01620	COG4251	negative regulation of phosphorylation
GQS55_RS01620	COG5001	Diguanylate cyclase
GQS55_RS01630	COG0584	glycerophosphoryl diester phosphodiesterase
GQS55_RS01635	COG1187	pseudouridine synthase activity
GQS55_RS01675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQS55_RS01680	COG2814	Major facilitator Superfamily
GQS55_RS01700	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS55_RS01700	COG1902	pentaerythritol trinitrate reductase activity
GQS55_RS01705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQS55_RS01720	COG0629	single-stranded DNA binding
GQS55_RS01730	COG3706	GGDEF domain
GQS55_RS01740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQS55_RS01745	COG0347	Belongs to the P(II) protein family
GQS55_RS01750	COG0004	ammonium transporteR
GQS55_RS01760	COG2205	protein histidine kinase activity
GQS55_RS01760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQS55_RS01760	COG2198	Histidine kinase
GQS55_RS01760	COG0784	Response regulator, receiver
GQS55_RS01765	COG2837	iron assimilation
GQS55_RS01775	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS01785	COG3706	GGDEF domain
GQS55_RS01785	COG0745	RESPONSE REGULATOR receiver
GQS55_RS01790	COG2001	Belongs to the MraZ family
GQS55_RS01795	COG0275	rRNA processing
GQS55_RS01800	COG3116	cell division
GQS55_RS01805	COG0768	penicillin binding
GQS55_RS01815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQS55_RS01820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQS55_RS01830	COG0772	Belongs to the SEDS family
GQS55_RS01840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQS55_RS01855	COG0849	cell division
GQS55_RS01860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS55_RS01865	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GQS55_RS01880	COG0653	protein targeting
GQS55_RS01905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GQS55_RS01910	COG1459	type II secretion system
GQS55_RS01915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQS55_RS01925	COG4969	Belongs to the N-Me-Phe pilin family
GQS55_RS01930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQS55_RS01935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQS55_RS01940	COG0723	plastoquinol--plastocyanin reductase activity
GQS55_RS01945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQS55_RS01950	COG2857	Cytochrome c1
GQS55_RS01955	COG0625	glutathione transferase activity
GQS55_RS01960	COG2969	positive regulation of protein catabolic process
GQS55_RS01965	COG2823	Periplasmic or secreted lipoprotein
GQS55_RS01970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GQS55_RS01985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GQS55_RS02000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GQS55_RS02005	COG3383	formate dehydrogenase (NAD+) activity
GQS55_RS02080	COG5001	Diguanylate cyclase
GQS55_RS02080	COG3300	MHYT domain
GQS55_RS02100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GQS55_RS02105	COG3118	belongs to the thioredoxin family
GQS55_RS02110	COG1968	undecaprenyl-diphosphatase activity
GQS55_RS02115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GQS55_RS02120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GQS55_RS02125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GQS55_RS02130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQS55_RS02135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GQS55_RS02140	COG1610	YqeY-like protein
GQS55_RS02145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQS55_RS02190	COG1077	Cell shape determining protein MreB Mrl
GQS55_RS02195	COG1792	Involved in formation and maintenance of cell shape
GQS55_RS02200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GQS55_RS02210	COG1530	ribonuclease E activity
GQS55_RS02215	COG3164	Protein of unknown function
GQS55_RS02220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQS55_RS02225	COG0312	modulator of DNA gyrase
GQS55_RS02235	COG0312	modulator of DNA gyrase
GQS55_RS02240	COG2239	Acts as a magnesium transporter
GQS55_RS02245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQS55_RS02250	COG1660	Displays ATPase and GTPase activities
GQS55_RS02265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GQS55_RS02270	COG1137	ATPase activity
GQS55_RS02285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GQS55_RS02300	COG1127	ABC transporter
GQS55_RS02305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQS55_RS02310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GQS55_RS02315	COG2854	intermembrane phospholipid transfer
GQS55_RS02325	COG5007	Belongs to the BolA IbaG family
GQS55_RS02330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQS55_RS02335	COG0506	proline dehydrogenase activity
GQS55_RS02335	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GQS55_RS02335	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GQS55_RS02350	COG0733	neurotransmitter:sodium symporter activity
GQS55_RS02355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS55_RS02365	COG1793	dna ligase
GQS55_RS02380	COG2827	Endonuclease containing a URI domain
GQS55_RS02400	COG1278	Cold shock
GQS55_RS02405	COG4771	TonB-dependent receptor
GQS55_RS02410	COG0457	Tetratricopeptide repeat
GQS55_RS02425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQS55_RS02430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GQS55_RS02435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS55_RS02440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GQS55_RS02445	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GQS55_RS02455	COG0564	pseudouridine synthase activity
GQS55_RS02470	COG2814	Major facilitator Superfamily
GQS55_RS02485	COG1505	serine-type exopeptidase activity
GQS55_RS02490	COG0583	DNA-binding transcription factor activity
GQS55_RS02495	COG2855	membrane
GQS55_RS02505	COG1509	lysine 2,3-aminomutase activity
GQS55_RS02510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQS55_RS02525	COG0668	transmembrane transport
GQS55_RS02530	COG4989	oxidoreductase activity
GQS55_RS02540	COG1131	(ABC) transporter
GQS55_RS02545	COG0842	Transport permease protein
GQS55_RS02550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQS55_RS02555	COG0076	glutamate decarboxylase activity
GQS55_RS02560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQS55_RS02565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQS55_RS02570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GQS55_RS02580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GQS55_RS02590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GQS55_RS02595	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQS55_RS02600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQS55_RS02605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQS55_RS02610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQS55_RS02615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQS55_RS02620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQS55_RS02625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQS55_RS02630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQS55_RS02635	COG1841	ribosomal large subunit assembly
GQS55_RS02640	COG0200	Binds to the 23S rRNA
GQS55_RS02645	COG0201	protein transport
GQS55_RS02655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQS55_RS02660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQS55_RS02665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQS55_RS02670	COG0202	RNA polymerase activity
GQS55_RS02675	COG0203	ribosomal protein L17
GQS55_RS02680	COG3954	Phosphoribulokinase
GQS55_RS02695	COG2234	aminopeptidase activity
GQS55_RS02710	COG1012	belongs to the aldehyde dehydrogenase family
GQS55_RS02720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQS55_RS02735	COG0633	Ferredoxin
GQS55_RS02735	COG3217	Mosc domain protein beta barrel domain protein
GQS55_RS02740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQS55_RS02750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GQS55_RS02770	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GQS55_RS02780	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GQS55_RS02785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GQS55_RS02790	COG0254	rRNA binding
GQS55_RS02795	COG0305	Participates in initiation and elongation during chromosome replication
GQS55_RS02800	COG0432	Pfam Uncharacterised protein family UPF0047
GQS55_RS02805	COG0583	DNA-binding transcription factor activity
GQS55_RS02815	COG4771	TonB-dependent receptor
GQS55_RS02825	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GQS55_RS02830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS55_RS02840	COG2193	ferroxidase activity
GQS55_RS02855	COG3590	peptidase
GQS55_RS02885	COG3300	MHYT domain
GQS55_RS02885	COG5001	Diguanylate cyclase
GQS55_RS02940	COG0778	Nitroreductase
GQS55_RS02950	COG0583	DNA-binding transcription factor activity
GQS55_RS02970	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GQS55_RS02975	COG4988	ABC transporter
GQS55_RS02985	COG1294	oxidase, subunit
GQS55_RS03015	COG4948	Mandelate Racemase Muconate Lactonizing
GQS55_RS03025	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS03040	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS03065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GQS55_RS03100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQS55_RS03140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQS55_RS03170	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQS55_RS03180	COG0010	Belongs to the arginase family
GQS55_RS03185	COG3047	cAMP biosynthetic process
GQS55_RS03185	COG2885	chlorophyll binding
GQS55_RS03220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GQS55_RS03235	COG0583	DNA-binding transcription factor activity
GQS55_RS03330	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GQS55_RS03335	COG1194	a g-specific adenine glycosylase
GQS55_RS03340	COG3171	Protein conserved in bacteria
GQS55_RS03345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQS55_RS03355	COG3852	Histidine kinase
GQS55_RS03360	COG0659	secondary active sulfate transmembrane transporter activity
GQS55_RS03365	COG3313	Fe-S protein
GQS55_RS03385	COG0463	Glycosyl transferase, family 2
GQS55_RS03425	COG0489	protein tyrosine kinase activity
GQS55_RS03425	COG3206	protein involved in exopolysaccharide biosynthesis
GQS55_RS03440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GQS55_RS03445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS55_RS03480	COG1215	transferase activity, transferring glycosyl groups
GQS55_RS03485	COG0367	asparagine synthase
GQS55_RS03495	COG1045	serine acetyltransferase
GQS55_RS03525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQS55_RS03530	COG0110	maltose O-acetyltransferase activity
GQS55_RS03595	COG5002	protein histidine kinase activity
GQS55_RS03595	COG0784	Response regulator, receiver
GQS55_RS03600	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GQS55_RS03615	COG1272	protein, Hemolysin III
GQS55_RS03630	COG4555	ABC transporter
GQS55_RS03650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQS55_RS03655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQS55_RS03660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQS55_RS03660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQS55_RS03690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS55_RS03695	COG4206	TonB-dependent receptor
GQS55_RS03730	COG1278	Cold shock
GQS55_RS03735	COG0525	valine-tRNA ligase activity
GQS55_RS03740	COG2927	DNA polymerase III (CHI subunit)
GQS55_RS03745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQS55_RS03750	COG0795	lipopolysaccharide-transporting ATPase activity
GQS55_RS03755	COG0795	lipopolysaccharide-transporting ATPase activity
GQS55_RS03770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS55_RS03785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS55_RS03805	COG1222	aaa ATPase
GQS55_RS03895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GQS55_RS03905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS55_RS03930	COG3335	DDE superfamily endonuclease
GQS55_RS03935	COG3335	DDE superfamily endonuclease
GQS55_RS03945	COG0348	domain, Protein
GQS55_RS03945	COG3901	Regulator of nitric oxide reductase transcription
GQS55_RS03960	COG1609	Transcriptional regulator
GQS55_RS03965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS55_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS03990	COG3706	GGDEF domain
GQS55_RS03990	COG2203	Gaf domain
GQS55_RS03990	COG4251	negative regulation of phosphorylation
GQS55_RS03990	COG5001	Diguanylate cyclase
GQS55_RS04000	COG4948	Mandelate Racemase Muconate Lactonizing
GQS55_RS04010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS55_RS04025	COG1056	cytidyltransferase-related domain
GQS55_RS04025	COG1051	belongs to the nudix hydrolase family
GQS55_RS04060	COG4771	TonB-dependent receptor
GQS55_RS04065	COG0457	Tetratricopeptide repeat
GQS55_RS04075	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GQS55_RS04095	COG0513	Belongs to the DEAD box helicase family
GQS55_RS04110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GQS55_RS04120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS55_RS04130	COG2971	BadF BadG BcrA BcrD
GQS55_RS04135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GQS55_RS04150	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GQS55_RS04155	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQS55_RS04160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQS55_RS04165	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQS55_RS04175	COG1138	Cytochrome C-type biogenesis protein
GQS55_RS04190	COG4235	cytochrome complex assembly
GQS55_RS04195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQS55_RS04200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQS55_RS04210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS55_RS04215	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GQS55_RS04250	COG5016	pyruvate
GQS55_RS04250	COG0511	ligase activity, forming carbon-carbon bonds
GQS55_RS04255	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GQS55_RS04270	COG0259	pyridoxamine-phosphate oxidase activity
GQS55_RS04280	COG1444	tRNA N-acetyltransferase activity
GQS55_RS04310	COG0653	protein targeting
GQS55_RS04350	COG0784	Response regulator, receiver
GQS55_RS04350	COG0835	chemotaxis
GQS55_RS04355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GQS55_RS04360	COG1815	bacterial-type flagellum-dependent cell motility
GQS55_RS04365	COG1558	bacterial-type flagellum-dependent cell motility
GQS55_RS04370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GQS55_RS04375	COG1749	Flagellar hook protein flgE
GQS55_RS04380	COG4786	Flagellar basal body rod
GQS55_RS04385	COG4786	Flagellar basal body rod
GQS55_RS04390	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GQS55_RS04395	COG1706	bacterial-type flagellum-dependent cell motility
GQS55_RS04405	COG1256	bacterial-type flagellum assembly
GQS55_RS04410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GQS55_RS04430	COG1334	flagellar protein FlaG
GQS55_RS04435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GQS55_RS04460	COG5002	protein histidine kinase activity
GQS55_RS04465	COG2204	response regulator
GQS55_RS04470	COG1677	Flagellar hook-basal body complex protein FliE
GQS55_RS04480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GQS55_RS04500	COG3144	bacterial-type flagellum assembly
GQS55_RS04520	COG3190	flagellar
GQS55_RS04530	COG1987	bacterial-type flagellum assembly
GQS55_RS04535	COG1684	flagellar biosynthetic protein fliR
GQS55_RS04555	COG0455	bacterial-type flagellum organization
GQS55_RS04570	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GQS55_RS04575	COG2198	Histidine kinase
GQS55_RS04575	COG0643	Histidine kinase
GQS55_RS04585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQS55_RS04590	COG1360	Flagellar Motor Protein
GQS55_RS04595	COG1192	Involved in chromosome partitioning
GQS55_RS04605	COG0835	chemotaxis
GQS55_RS04615	COG2853	Lipoprotein
GQS55_RS04620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQS55_RS04625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS55_RS04630	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GQS55_RS04635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GQS55_RS04650	COG0513	Belongs to the DEAD box helicase family
GQS55_RS04655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GQS55_RS04735	COG1757	Na H antiporter
GQS55_RS04740	COG0165	Argininosuccinate lyase
GQS55_RS04745	COG3706	GGDEF domain
GQS55_RS04760	COG4206	TonB-dependent receptor
GQS55_RS04795	COG3106	COG3106 Predicted ATPase
GQS55_RS04810	COG2154	pterin-4-alpha-carbinolamine dehydratase
GQS55_RS04825	COG0625	glutathione transferase activity
GQS55_RS04830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQS55_RS04835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GQS55_RS04840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQS55_RS04845	COG3104	oligopeptide transport
GQS55_RS04850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS55_RS04865	COG1560	Kdo2-lipid A biosynthetic process
GQS55_RS04870	COG1538	Outer membrane efflux protein
GQS55_RS04875	COG0494	nUDIX hydrolase
GQS55_RS04880	COG3151	Protein conserved in bacteria
GQS55_RS04890	COG3150	esterase
GQS55_RS04895	COG0187	DNA topoisomerase II activity
GQS55_RS04905	COG3706	GGDEF domain
GQS55_RS04920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GQS55_RS04945	COG0745	RESPONSE REGULATOR receiver
GQS55_RS04960	COG0745	RESPONSE REGULATOR receiver
GQS55_RS04965	COG0840	transmembrane signaling receptor activity
GQS55_RS04970	COG3300	MHYT domain
GQS55_RS04970	COG5001	Diguanylate cyclase
GQS55_RS04975	COG1917	Cupin 2, conserved barrel domain protein
GQS55_RS04975	COG4977	sequence-specific DNA binding
GQS55_RS04985	COG3118	belongs to the thioredoxin family
GQS55_RS04995	COG3134	Outer membrane lipoprotein
GQS55_RS05015	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS05030	COG3112	Uncharacterised protein family (UPF0231)
GQS55_RS05045	COG2814	Major facilitator Superfamily
GQS55_RS05070	COG0271	Belongs to the BolA IbaG family
GQS55_RS05075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQS55_RS05080	COG3706	GGDEF domain
GQS55_RS05080	COG2203	Gaf domain
GQS55_RS05080	COG5001	Diguanylate cyclase
GQS55_RS05080	COG4251	negative regulation of phosphorylation
GQS55_RS05085	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQS55_RS05090	COG1805	sodium ion transport
GQS55_RS05100	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQS55_RS05105	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQS55_RS05110	COG2871	sodium ion transport
GQS55_RS05115	COG1477	protein flavinylation
GQS55_RS05125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQS55_RS05130	COG0142	geranyltranstransferase activity
GQS55_RS05135	COG1722	exodeoxyribonuclease VII activity
GQS55_RS05140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GQS55_RS05150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS55_RS05150	COG0301	tRNA thio-modification
GQS55_RS05155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQS55_RS05165	COG1666	GTP binding
GQS55_RS05170	COG5507	3-demethylubiquinone-9 3-methyltransferase
GQS55_RS05185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GQS55_RS05195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQS55_RS05200	COG1595	DNA-templated transcription, initiation
GQS55_RS05210	COG3026	antisigma factor binding
GQS55_RS05220	COG0481	GTPase activity
GQS55_RS05225	COG0681	Belongs to the peptidase S26 family
GQS55_RS05230	COG0571	ribonuclease III activity
GQS55_RS05240	COG1381	Involved in DNA repair and RecF pathway recombination
GQS55_RS05245	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GQS55_RS05260	COG3437	response regulator, receiver
GQS55_RS05260	COG3850	Histidine kinase
GQS55_RS05260	COG4999	Histidine kinase
GQS55_RS05260	COG2205	protein histidine kinase activity
GQS55_RS05270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQS55_RS05275	COG3956	TIGRFAM MazG family protein
GQS55_RS05285	COG2832	Protein of unknown function (DUF454)
GQS55_RS05295	COG0504	CTP synthase activity
GQS55_RS05310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GQS55_RS05320	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GQS55_RS05330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQS55_RS05335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQS55_RS05340	COG1238	metal cluster binding
GQS55_RS05345	COG1388	LysM domain
GQS55_RS05345	COG4942	peptidase
GQS55_RS05350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQS55_RS05360	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQS55_RS05365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQS55_RS05375	COG1410	methionine synthase
GQS55_RS05375	COG0646	methionine synthase
GQS55_RS05390	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GQS55_RS05400	COG0560	Phosphoserine phosphatase
GQS55_RS05410	COG0084	hydrolase, TatD family'
GQS55_RS05415	COG0047	phosphoribosylformylglycinamidine synthase activity
GQS55_RS05415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQS55_RS05420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GQS55_RS05425	COG2356	endonuclease I
GQS55_RS05435	COG0590	tRNA wobble adenosine to inosine editing
GQS55_RS05440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQS55_RS05445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQS55_RS05455	COG0762	integral membrane protein
GQS55_RS05460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQS55_RS05465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GQS55_RS05480	COG0517	IMP dehydrogenase activity
GQS55_RS05480	COG0516	GMP reductase activity
GQS55_RS05490	COG1392	Phosphate transport regulator
GQS55_RS05495	COG0306	phosphate transporter
GQS55_RS05500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS55_RS05505	COG0583	DNA-binding transcription factor activity
GQS55_RS05515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GQS55_RS05520	COG1346	cytolysis
GQS55_RS05555	COG3588	fructose-bisphosphate aldolase
GQS55_RS05560	COG0126	phosphoglycerate kinase activity
GQS55_RS05565	COG2974	May be involved in recombination
GQS55_RS05570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQS55_RS05570	COG4191	Histidine kinase
GQS55_RS05580	COG0745	RESPONSE REGULATOR receiver
GQS55_RS05590	COG0019	diaminopimelate decarboxylase activity
GQS55_RS05615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQS55_RS05620	COG1757	Na H antiporter
GQS55_RS05640	COG4948	Mandelate Racemase Muconate Lactonizing
GQS55_RS05660	COG3876	Protein conserved in bacteria
GQS55_RS05675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQS55_RS05695	COG0739	heme binding
GQS55_RS05695	COG0741	lytic transglycosylase activity
GQS55_RS05695	COG1196	nuclear chromosome segregation
GQS55_RS05720	COG0488	(ABC) transporter
GQS55_RS05730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS55_RS05735	COG0640	Transcriptional regulator
GQS55_RS05755	COG0019	diaminopimelate decarboxylase activity
GQS55_RS05760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQS55_RS05770	COG0189	ligase activity
GQS55_RS05775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GQS55_RS05785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQS55_RS05815	COG3335	DDE superfamily endonuclease
GQS55_RS05830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQS55_RS05835	COG0023	Translation Initiation Factor
GQS55_RS05880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS55_RS05885	COG3647	Membrane
GQS55_RS05890	COG0564	pseudouridine synthase activity
GQS55_RS05910	COG0018	arginyl-trna synthetase
GQS55_RS05915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GQS55_RS05935	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GQS55_RS05940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GQS55_RS05945	COG0343	queuine tRNA-ribosyltransferase activity
GQS55_RS05950	COG1862	Preprotein translocase
GQS55_RS05955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS55_RS05960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS55_RS05965	COG0513	Belongs to the DEAD box helicase family
GQS55_RS05970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQS55_RS05970	COG1648	precorrin-2 dehydrogenase activity
GQS55_RS05975	COG0483	inositol monophosphate 1-phosphatase activity
GQS55_RS05980	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GQS55_RS05985	COG1045	serine acetyltransferase
GQS55_RS05990	COG1959	2 iron, 2 sulfur cluster binding
GQS55_RS05995	COG1104	cysteine desulfurase activity
GQS55_RS06000	COG0822	iron-sulfur transferase activity
GQS55_RS06015	COG0443	Heat shock 70 kDa protein
GQS55_RS06040	COG0840	transmembrane signaling receptor activity
GQS55_RS06065	COG0402	S-adenosylhomocysteine deaminase activity
GQS55_RS06070	COG4771	TonB-dependent receptor
GQS55_RS06075	COG1595	DNA-templated transcription, initiation
GQS55_RS06085	COG0826	peptidase U32
GQS55_RS06090	COG2354	Protein conserved in bacteria
GQS55_RS06145	COG0564	pseudouridine synthase activity
GQS55_RS06150	COG0217	transcriptional regulatory protein
GQS55_RS06160	COG0408	coproporphyrinogen oxidase activity
GQS55_RS06170	COG3038	cytochrome b561
GQS55_RS06175	COG0583	DNA-binding transcription factor activity
GQS55_RS06190	COG3079	Belongs to the UPF0149 family
GQS55_RS06195	COG0006	proline dipeptidase activity
GQS55_RS06200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS55_RS06205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS55_RS06210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQS55_RS06220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS55_RS06220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS55_RS06240	COG4628	conserved protein (DUF2132)
GQS55_RS06250	COG0545	Peptidyl-prolyl cis-trans isomerase
GQS55_RS06260	COG0513	Belongs to the DEAD box helicase family
GQS55_RS06265	COG3706	GGDEF domain
GQS55_RS06265	COG0745	RESPONSE REGULATOR receiver
GQS55_RS06270	COG3842	ATPase activity
GQS55_RS06275	COG1178	ABC-type Fe3 transport system permease component
GQS55_RS06305	COG0625	glutathione transferase activity
GQS55_RS06315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS55_RS06330	COG1538	Outer membrane efflux protein
GQS55_RS06365	COG2205	protein histidine kinase activity
GQS55_RS06370	COG0745	RESPONSE REGULATOR receiver
GQS55_RS06395	COG0697	spore germination
GQS55_RS06405	COG4191	Histidine kinase
GQS55_RS06405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQS55_RS06410	COG5001	Diguanylate cyclase
GQS55_RS06410	COG3706	GGDEF domain
GQS55_RS06410	COG2203	Gaf domain
GQS55_RS06410	COG4251	negative regulation of phosphorylation
GQS55_RS06435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQS55_RS06480	COG0745	RESPONSE REGULATOR receiver
GQS55_RS06495	COG0228	four-way junction DNA binding
GQS55_RS06500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQS55_RS06505	COG0336	Belongs to the RNA methyltransferase TrmD family
GQS55_RS06510	COG0335	large ribosomal subunit rRNA binding
GQS55_RS06535	COG3328	transposase activity
GQS55_RS06540	COG1429	ligase activity, forming nitrogen-metal bonds
GQS55_RS06560	COG4206	TonB-dependent receptor
GQS55_RS06590	COG1999	signal sequence binding
GQS55_RS06610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQS55_RS06615	COG2867	negative regulation of translational initiation
GQS55_RS06640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS55_RS06640	COG0116	Belongs to the methyltransferase superfamily
GQS55_RS06685	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS55_RS06685	COG1902	pentaerythritol trinitrate reductase activity
GQS55_RS06700	COG0778	Nitroreductase
GQS55_RS06705	COG0183	Belongs to the thiolase family
GQS55_RS06710	COG2365	Tyrosine phosphatase family
GQS55_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS06725	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS06735	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS06740	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS06755	COG2186	Transcriptional regulator
GQS55_RS06760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS55_RS06765	COG1454	alcohol dehydrogenase
GQS55_RS06780	COG0318	PFAM AMP-dependent synthetase and ligase
GQS55_RS06790	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GQS55_RS06795	COG2814	Major facilitator Superfamily
GQS55_RS06800	COG1566	PFAM secretion protein HlyD family protein
GQS55_RS06830	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS06840	COG0346	lactoylglutathione lyase activity
GQS55_RS06880	COG1024	Enoyl-CoA hydratase
GQS55_RS06885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQS55_RS06895	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS06900	COG1024	Enoyl-CoA hydratase
GQS55_RS06900	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS55_RS06905	COG0183	Belongs to the thiolase family
GQS55_RS06915	COG1024	Enoyl-CoA hydratase
GQS55_RS06920	COG0778	Nitroreductase
GQS55_RS06925	COG0318	PFAM AMP-dependent synthetase and ligase
GQS55_RS06970	COG1022	Amp-dependent synthetase and ligase
GQS55_RS06975	COG0778	Nitroreductase
GQS55_RS06980	COG0183	Belongs to the thiolase family
GQS55_RS07015	COG2030	dehydratase
GQS55_RS07020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GQS55_RS07030	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS55_RS07045	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS07050	COG1053	succinate dehydrogenase
GQS55_RS07055	COG2223	nitrite transmembrane transporter activity
GQS55_RS07060	COG2223	nitrite transmembrane transporter activity
GQS55_RS07065	COG4771	TonB-dependent receptor
GQS55_RS07080	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS07100	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS07130	COG1063	alcohol dehydrogenase
GQS55_RS07150	COG1802	Transcriptional regulator
GQS55_RS07165	COG1063	alcohol dehydrogenase
GQS55_RS07180	COG1024	Enoyl-CoA hydratase
GQS55_RS07220	COG1024	Enoyl-CoA hydratase
GQS55_RS07235	COG1902	pentaerythritol trinitrate reductase activity
GQS55_RS07240	COG1024	Enoyl-CoA hydratase
GQS55_RS07265	COG2186	Transcriptional regulator
GQS55_RS07290	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS07295	COG1024	Enoyl-CoA hydratase
GQS55_RS07340	COG0583	DNA-binding transcription factor activity
GQS55_RS07345	COG0247	lactate metabolic process
GQS55_RS07350	COG1139	Iron-sulfur cluster binding protein
GQS55_RS07375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GQS55_RS07385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS55_RS07400	COG1063	alcohol dehydrogenase
GQS55_RS07420	COG1595	DNA-templated transcription, initiation
GQS55_RS07430	COG2202	Pas domain
GQS55_RS07430	COG2205	protein histidine kinase activity
GQS55_RS07440	COG3901	Regulator of nitric oxide reductase transcription
GQS55_RS07440	COG0348	domain, Protein
GQS55_RS07445	COG1012	belongs to the aldehyde dehydrogenase family
GQS55_RS07475	COG1131	(ABC) transporter
GQS55_RS07535	COG4206	TonB-dependent receptor
GQS55_RS07570	COG1119	ATPase activity
GQS55_RS07575	COG0513	Belongs to the DEAD box helicase family
GQS55_RS07585	COG0288	reversible hydration of carbon dioxide
GQS55_RS07600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQS55_RS07630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQS55_RS07665	COG0697	spore germination
GQS55_RS07680	COG4681	YaeQ
GQS55_RS07685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQS55_RS07700	COG1595	DNA-templated transcription, initiation
GQS55_RS07705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQS55_RS07710	COG4660	Part of a membrane complex involved in electron transport
GQS55_RS07715	COG4659	FMN binding
GQS55_RS07720	COG4658	electron transport chain
GQS55_RS07725	COG4656	Part of a membrane complex involved in electron transport
GQS55_RS07730	COG2878	Part of a membrane complex involved in electron transport
GQS55_RS07735	COG4657	Part of a membrane complex involved in electron transport
GQS55_RS07750	COG0779	Required for maturation of 30S ribosomal subunits
GQS55_RS07755	COG0195	Participates in both transcription termination and antitermination
GQS55_RS07760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQS55_RS07765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQS55_RS07770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQS55_RS07775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQS55_RS07780	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS55_RS07840	COG0012	GTP binding
GQS55_RS07845	COG0193	aminoacyl-tRNA hydrolase activity
GQS55_RS07850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GQS55_RS07855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQS55_RS07870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQS55_RS07875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQS55_RS07880	COG2890	protein-(glutamine-N5) methyltransferase activity
GQS55_RS07885	COG3094	Invasion gene expression up-regulator, SirB
GQS55_RS07890	COG2912	Transglutaminase-like superfamily
GQS55_RS07900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GQS55_RS07910	COG0583	DNA-binding transcription factor activity
GQS55_RS07920	COG2363	Small membrane protein
GQS55_RS07925	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GQS55_RS07930	COG0473	3-isopropylmalate dehydrogenase activity
GQS55_RS07940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQS55_RS07945	COG1611	Belongs to the LOG family
GQS55_RS07950	COG3706	GGDEF domain
GQS55_RS07985	COG2186	Transcriptional regulator
GQS55_RS08010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GQS55_RS08015	COG0450	alkyl hydroperoxide reductase
GQS55_RS08020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQS55_RS08035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQS55_RS08040	COG1534	Rna-binding protein
GQS55_RS08045	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GQS55_RS08050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS55_RS08055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQS55_RS08060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS55_RS08065	COG0149	triose-phosphate isomerase activity
GQS55_RS08070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQS55_RS08095	COG5002	protein histidine kinase activity
GQS55_RS08100	COG0243	molybdopterin cofactor binding
GQS55_RS08150	COG0577	efflux transmembrane transporter activity
GQS55_RS08150	COG1136	(ABC) transporter
GQS55_RS08175	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GQS55_RS08180	COG0483	inositol monophosphate 1-phosphatase activity
GQS55_RS08190	COG0745	RESPONSE REGULATOR receiver
GQS55_RS08195	COG2205	protein histidine kinase activity
GQS55_RS08200	COG0628	permease
GQS55_RS08275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQS55_RS08280	COG0513	Belongs to the DEAD box helicase family
GQS55_RS08285	COG0069	glutamate synthase activity
GQS55_RS08290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GQS55_RS08295	COG0488	(ABC) transporter
GQS55_RS08340	COG1959	2 iron, 2 sulfur cluster binding
GQS55_RS08355	COG0513	Belongs to the DEAD box helicase family
GQS55_RS08360	COG1032	radical SAM domain protein
GQS55_RS08395	COG0559	Belongs to the binding-protein-dependent transport system permease family
GQS55_RS08410	COG0410	ABC transporter
GQS55_RS08425	COG3328	transposase activity
GQS55_RS08435	COG1025	Belongs to the peptidase M16 family
GQS55_RS08445	COG2840	Smr protein MutS2
GQS55_RS08455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQS55_RS08460	COG0071	Belongs to the small heat shock protein (HSP20) family
GQS55_RS08465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GQS55_RS08475	COG3706	GGDEF domain
GQS55_RS08485	COG4535	Mg2 and Co2 transporter CorC
GQS55_RS08495	COG1702	phosphate starvation-inducible protein PhoH
GQS55_RS08500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS55_RS08505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS55_RS08510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQS55_RS08515	COG2915	High frequency lysogenization protein hflD homolog
GQS55_RS08520	COG0482	sulfurtransferase activity
GQS55_RS08525	COG1187	pseudouridine synthase activity
GQS55_RS08535	COG0513	Belongs to the DEAD box helicase family
GQS55_RS08545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GQS55_RS08560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GQS55_RS08565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GQS55_RS08580	COG1024	Enoyl-CoA hydratase
GQS55_RS08585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS55_RS08590	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS08600	COG0183	Belongs to the thiolase family
GQS55_RS08610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GQS55_RS08620	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS08645	COG3335	DDE superfamily endonuclease
GQS55_RS08655	COG0583	DNA-binding transcription factor activity
GQS55_RS08670	COG0123	including yeast histone deacetylase and acetoin utilization protein
GQS55_RS08675	COG0427	acetyl-CoA hydrolase
GQS55_RS08690	COG0110	maltose O-acetyltransferase activity
GQS55_RS08705	COG1403	HNH endonuclease
GQS55_RS08725	COG0328	RNA-DNA hybrid ribonuclease activity
GQS55_RS08740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GQS55_RS08760	COG1309	transcriptional regulator
GQS55_RS08775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQS55_RS08805	COG0811	peptide transport
GQS55_RS08810	COG0811	peptide transport
GQS55_RS08815	COG0848	biopolymer transport protein
GQS55_RS08820	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GQS55_RS08835	COG1803	Methylglyoxal synthase
GQS55_RS08840	COG1944	ATP diphosphatase activity
GQS55_RS08865	COG5002	protein histidine kinase activity
GQS55_RS08870	COG3273	potassium ion transport
GQS55_RS08870	COG0471	metal ion transport
GQS55_RS08875	COG0640	Transcriptional regulator
GQS55_RS08885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQS55_RS08895	COG4651	solute:proton antiporter activity
GQS55_RS08895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS55_RS08905	COG4181	ATPase activity
GQS55_RS08915	COG0628	permease
GQS55_RS08935	COG0515	serine threonine protein kinase
GQS55_RS08935	COG2815	serine threonine protein kinase
GQS55_RS08965	COG0631	protein serine/threonine phosphatase activity
GQS55_RS09020	COG3501	Rhs element vgr protein
GQS55_RS09045	COG3209	COG3209 Rhs family protein
GQS55_RS09085	COG2350	Protein conserved in bacteria
GQS55_RS09100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQS55_RS09110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQS55_RS09120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQS55_RS09125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQS55_RS09130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQS55_RS09135	COG0539	negative regulation of cytoplasmic translation
GQS55_RS09140	COG0776	regulation of translation
GQS55_RS09150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GQS55_RS09155	COG0284	orotidine-5'-phosphate decarboxylase activity
GQS55_RS09165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GQS55_RS09190	COG2920	part of a sulfur-relay system
GQS55_RS09210	COG0670	Belongs to the BI1 family
GQS55_RS09215	COG0519	Catalyzes the synthesis of GMP from XMP
GQS55_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS09255	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS09265	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS09270	COG0183	Belongs to the thiolase family
GQS55_RS09275	COG0318	PFAM AMP-dependent synthetase and ligase
GQS55_RS09280	COG2130	NADP-dependent
GQS55_RS09285	COG0596	Alpha beta hydrolase
GQS55_RS09290	COG1024	Enoyl-CoA hydratase
GQS55_RS09310	COG0596	Alpha beta hydrolase
GQS55_RS09315	COG0778	Nitroreductase
GQS55_RS09320	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS09375	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS09400	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS09445	COG5001	Diguanylate cyclase
GQS55_RS09445	COG4251	negative regulation of phosphorylation
GQS55_RS09445	COG2203	Gaf domain
GQS55_RS09445	COG3706	GGDEF domain
GQS55_RS09475	COG3012	SEC-C Motif Domain Protein
GQS55_RS09500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQS55_RS09535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQS55_RS09540	COG0427	acetyl-CoA hydrolase
GQS55_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS09570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQS55_RS09575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQS55_RS09580	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GQS55_RS09585	COG0574	Belongs to the PEP-utilizing enzyme family
GQS55_RS09585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS55_RS09610	COG0420	3'-5' exonuclease activity
GQS55_RS09615	COG0419	ATPase involved in DNA repair
GQS55_RS09625	COG1047	Peptidyl-prolyl cis-trans
GQS55_RS09630	COG1228	amidohydrolase
GQS55_RS09650	COG4651	solute:proton antiporter activity
GQS55_RS09650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS55_RS09655	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GQS55_RS09660	COG1074	ATP-dependent DNA helicase activity
GQS55_RS09665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQS55_RS09675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQS55_RS09680	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GQS55_RS09690	COG0492	ferredoxin-NADP+ reductase activity
GQS55_RS09695	COG0686	Belongs to the AlaDH PNT family
GQS55_RS09705	COG1674	ftsk spoiiie
GQS55_RS09705	COG0531	amino acid
GQS55_RS09710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GQS55_RS09715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQS55_RS09720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQS55_RS09725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQS55_RS09735	COG2866	Carboxypeptidase
GQS55_RS09740	COG1115	amino acid carrier protein
GQS55_RS09760	COG0252	asparaginase activity
GQS55_RS09775	COG5002	protein histidine kinase activity
GQS55_RS09775	COG0784	Response regulator, receiver
GQS55_RS09780	COG0784	Response regulator, receiver
GQS55_RS09785	COG4251	negative regulation of phosphorylation
GQS55_RS09820	COG0017	Asparaginyl-tRNA synthetase
GQS55_RS09830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQS55_RS09835	COG1073	alpha beta
GQS55_RS09835	COG2226	methyltransferase
GQS55_RS09850	COG1070	Carbohydrate kinase
GQS55_RS09855	COG0400	carboxylic ester hydrolase activity
GQS55_RS09870	COG1280	lysine exporter protein (LysE YggA)
GQS55_RS09920	COG0625	glutathione transferase activity
GQS55_RS09935	COG0454	-acetyltransferase
GQS55_RS09955	COG0730	response to heat
GQS55_RS09965	COG1957	nucleoside hydrolase
GQS55_RS09970	COG1506	peptidase
GQS55_RS09980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQS55_RS10010	COG2894	cell division
GQS55_RS10015	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GQS55_RS10020	COG0277	FAD linked oxidase domain protein
GQS55_RS10125	COG2003	Belongs to the UPF0758 family
GQS55_RS10150	COG2356	endonuclease I
GQS55_RS10175	COG0582	viral genome integration into host DNA
GQS55_RS10185	COG2003	Belongs to the UPF0758 family
GQS55_RS10210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQS55_RS10215	COG0582	viral genome integration into host DNA
GQS55_RS10230	COG3082	Protein of unknown function (DUF1414)
GQS55_RS10235	COG3081	Nucleoid-associated protein
GQS55_RS10240	COG0418	dihydroorotase activity
GQS55_RS10275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GQS55_RS10300	COG4771	TonB-dependent receptor
GQS55_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS10360	COG1940	carbohydrate kinase activity
GQS55_RS10365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GQS55_RS10370	COG1609	Transcriptional regulator
GQS55_RS10385	COG0166	Belongs to the GPI family
GQS55_RS10395	COG3328	transposase activity
GQS55_RS10400	COG0583	DNA-binding transcription factor activity
GQS55_RS10410	COG2375	cellular response to nickel ion
GQS55_RS10430	COG3977	Valine--pyruvate aminotransferase
GQS55_RS10440	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GQS55_RS10455	COG0730	response to heat
GQS55_RS10480	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS10505	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS10540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQS55_RS10590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQS55_RS10595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS55_RS10600	COG0813	purine-nucleoside phosphorylase activity
GQS55_RS10610	COG1279	arginine transmembrane transporter activity
GQS55_RS10620	COG0572	uridine kinase
GQS55_RS10625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQS55_RS10635	COG1435	thymidine kinase activity
GQS55_RS10665	COG4633	Protein conserved in bacteria
GQS55_RS10670	COG0642	Histidine kinase
GQS55_RS10675	COG0745	RESPONSE REGULATOR receiver
GQS55_RS10695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS55_RS10700	COG0367	asparagine synthase
GQS55_RS10705	COG0745	RESPONSE REGULATOR receiver
GQS55_RS10705	COG3706	GGDEF domain
GQS55_RS10725	COG0167	dihydroorotate dehydrogenase activity
GQS55_RS10730	COG2902	Dehydrogenase
GQS55_RS10740	COG4447	cellulose binding
GQS55_RS10760	COG0308	aminopeptidase N
GQS55_RS10775	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GQS55_RS10785	COG1956	GAF domain-containing protein
GQS55_RS10805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GQS55_RS10810	COG0372	Belongs to the citrate synthase family
GQS55_RS10815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GQS55_RS10820	COG2186	Transcriptional regulator
GQS55_RS10850	COG0717	Belongs to the dCTP deaminase family
GQS55_RS10855	COG0489	protein tyrosine kinase activity
GQS55_RS10860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS55_RS10860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS55_RS10875	COG1720	tRNA m6t6A37 methyltransferase activity
GQS55_RS10890	COG1404	Belongs to the peptidase S8 family
GQS55_RS10900	COG1454	alcohol dehydrogenase
GQS55_RS10905	COG1770	oligopeptidase
GQS55_RS10925	COG0653	protein targeting
GQS55_RS10930	COG5001	Diguanylate cyclase
GQS55_RS10940	COG2133	pyrroloquinoline quinone binding
GQS55_RS10960	COG3220	belongs to the UPF0276 family
GQS55_RS10975	COG4771	TonB-dependent receptor
GQS55_RS10980	COG3036	rescue of stalled ribosome
GQS55_RS11010	COG1595	DNA-templated transcription, initiation
GQS55_RS11055	COG1794	racemase activity, acting on amino acids and derivatives
GQS55_RS11065	COG0024	Methionine aminopeptidase
GQS55_RS11110	COG0714	Associated with various cellular activities
GQS55_RS11120	COG0312	modulator of DNA gyrase
GQS55_RS11125	COG0312	modulator of DNA gyrase
GQS55_RS11130	COG0708	Exodeoxyribonuclease III
GQS55_RS11135	COG2226	methyltransferase
GQS55_RS11150	COG1393	Belongs to the ArsC family
GQS55_RS11155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS55_RS11160	COG1876	peptidase activity
GQS55_RS11195	COG2716	regulation of RNA biosynthetic process
GQS55_RS11215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQS55_RS11240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQS55_RS11295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GQS55_RS11295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQS55_RS11300	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GQS55_RS11305	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GQS55_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
GQS55_RS11330	COG4191	Histidine kinase
GQS55_RS11345	COG4783	chaperone-mediated protein folding
GQS55_RS11350	COG1393	Belongs to the ArsC family
GQS55_RS11370	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS55_RS11385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQS55_RS11390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GQS55_RS11400	COG0121	glutamine amidotransferase
GQS55_RS11405	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS11415	COG0776	regulation of translation
GQS55_RS11420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS55_RS11420	COG0072	phenylalanine-tRNA ligase activity
GQS55_RS11425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQS55_RS11430	COG3005	denitrification pathway
GQS55_RS11435	COG3043	anaerobic respiration
GQS55_RS11440	COG0243	molybdopterin cofactor binding
GQS55_RS11450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS55_RS11455	COG4459	periplasmic nitrate reductase
GQS55_RS11465	COG0247	lactate metabolic process
GQS55_RS11465	COG0277	FAD linked oxidase domain protein
GQS55_RS11480	COG0602	queuosine metabolic process
GQS55_RS11485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GQS55_RS11490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS55_RS11495	COG0556	nucleotide-excision repair
GQS55_RS11500	COG0534	Mate efflux family protein
GQS55_RS11540	COG0542	response to heat
GQS55_RS11545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GQS55_RS11550	COG1278	Cold shock
GQS55_RS11560	COG1643	Atp-dependent helicase
GQS55_RS11565	COG0516	GMP reductase activity
GQS55_RS11565	COG0517	IMP dehydrogenase activity
GQS55_RS11570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQS55_RS11580	COG1984	allophanate hydrolase subunit 2
GQS55_RS11585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GQS55_RS11595	COG4336	lyase activity
GQS55_RS11615	COG0517	IMP dehydrogenase activity
GQS55_RS11630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS55_RS11635	COG1136	(ABC) transporter
GQS55_RS11635	COG0577	efflux transmembrane transporter activity
GQS55_RS11640	COG1451	nucleotide metabolic process
GQS55_RS11645	COG4771	TonB-dependent receptor
GQS55_RS11660	COG4716	Myosin-crossreactive antigen
GQS55_RS11680	COG0789	Transcriptional regulator
GQS55_RS11685	COG2130	NADP-dependent
GQS55_RS11690	COG1979	alcohol dehydrogenase
GQS55_RS11700	COG0583	DNA-binding transcription factor activity
GQS55_RS11710	COG2382	esterase
GQS55_RS11755	COG0527	aspartate kinase activity
GQS55_RS11760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GQS55_RS11770	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GQS55_RS11775	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GQS55_RS11790	COG2983	Belongs to the UPF0260 family
GQS55_RS11795	COG2951	lytic endotransglycosylase activity
GQS55_RS11815	COG1187	pseudouridine synthase activity
GQS55_RS11820	COG0009	L-threonylcarbamoyladenylate synthase
GQS55_RS11825	COG0613	PHP domain protein
GQS55_RS11830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQS55_RS11835	COG0512	Glutamine amidotransferase of anthranilate synthase
GQS55_RS11845	COG0135	phosphoribosylanthranilate isomerase activity
GQS55_RS11845	COG0134	indole-3-glycerol-phosphate synthase activity
GQS55_RS11885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS55_RS11900	COG0582	viral genome integration into host DNA
GQS55_RS11905	COG2925	Exonuclease
GQS55_RS11925	COG0471	metal ion transport
GQS55_RS11930	COG2084	Dehydrogenase
GQS55_RS11945	COG0386	Belongs to the glutathione peroxidase family
GQS55_RS11950	COG1846	Transcriptional regulator
GQS55_RS11975	COG4206	TonB-dependent receptor
GQS55_RS11980	COG0531	amino acid
GQS55_RS12000	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQS55_RS12010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS55_RS12015	COG0693	protein deglycase activity
GQS55_RS12030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS55_RS12075	COG2202	Pas domain
GQS55_RS12075	COG2200	EAL domain
GQS55_RS12075	COG2199	diguanylate cyclase activity
GQS55_RS12085	COG3706	GGDEF domain
GQS55_RS12085	COG0745	RESPONSE REGULATOR receiver
GQS55_RS12115	COG4249	Peptidase C14 caspase catalytic subunit p20
GQS55_RS12115	COG2319	Wd-40 repeat
GQS55_RS12135	COG1278	Cold shock
GQS55_RS12140	COG0084	hydrolase, TatD family'
GQS55_RS12155	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQS55_RS12180	COG0729	surface antigen
GQS55_RS12185	COG2911	Protein conserved in bacteria
GQS55_RS12190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQS55_RS12195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQS55_RS12200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS55_RS12205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQS55_RS12215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GQS55_RS12220	COG0416	fatty acid biosynthetic process
GQS55_RS12225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQS55_RS12230	COG1399	metal-binding, possibly nucleic acid-binding protein
GQS55_RS12260	COG1530	ribonuclease E activity
GQS55_RS12265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS55_RS12275	COG1280	lysine exporter protein (LysE YggA)
GQS55_RS12280	COG0442	prolyl-tRNA aminoacylation
GQS55_RS12285	COG0436	Aminotransferase
GQS55_RS12290	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GQS55_RS12295	COG0784	Response regulator, receiver
GQS55_RS12295	COG3437	response regulator, receiver
GQS55_RS12305	COG0028	Belongs to the TPP enzyme family
GQS55_RS12320	COG1254	Belongs to the acylphosphatase family
GQS55_RS12330	COG3275	phosphorelay sensor kinase activity
GQS55_RS12335	COG0537	adenosine 5'-monophosphoramidase activity
GQS55_RS12345	COG0295	cytidine deaminase activity
GQS55_RS12365	COG1785	Belongs to the alkaline phosphatase family
GQS55_RS12375	COG0626	cystathionine gamma-synthase activity
GQS55_RS12385	COG0417	DNA replication proofreading
GQS55_RS12390	COG1199	ATP-dependent helicase activity
GQS55_RS12420	COG0028	Belongs to the TPP enzyme family
GQS55_RS12425	COG0457	Tetratricopeptide repeat
GQS55_RS12430	COG4771	TonB-dependent receptor
GQS55_RS12435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GQS55_RS12440	COG1846	Transcriptional regulator
GQS55_RS12450	COG0745	RESPONSE REGULATOR receiver
GQS55_RS12455	COG2205	protein histidine kinase activity
GQS55_RS12470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQS55_RS12495	COG2226	methyltransferase
GQS55_RS12500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS55_RS12505	COG0741	lytic transglycosylase activity
GQS55_RS12505	COG1388	LysM domain
GQS55_RS12515	COG3278	Belongs to the heme-copper respiratory oxidase family
GQS55_RS12530	COG2010	Cytochrome c
GQS55_RS12555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS55_RS12580	COG1960	acyl-CoA dehydrogenase activity
GQS55_RS12590	COG0800	Aldolase
GQS55_RS12595	COG0129	dihydroxy-acid dehydratase activity
GQS55_RS12600	COG0363	glucosamine-6-phosphate deaminase activity
GQS55_RS12605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GQS55_RS12610	COG1737	Transcriptional regulator
GQS55_RS12615	COG0469	pyruvate kinase activity
GQS55_RS12655	COG5265	(ABC) transporter
GQS55_RS12690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQS55_RS12695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQS55_RS12700	COG3122	Protein conserved in bacteria
GQS55_RS12715	COG0746	molybdenum cofactor guanylyltransferase activity
GQS55_RS12735	COG1605	Chorismate mutase
GQS55_RS12735	COG0077	Prephenate dehydratase
GQS55_RS12740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQS55_RS12745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS55_RS12765	COG0287	Prephenate dehydrogenase
GQS55_RS12765	COG1605	Chorismate mutase
GQS55_RS12770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQS55_RS12785	COG1573	uracil-dna glycosylase
GQS55_RS12815	COG0006	proline dipeptidase activity
GQS55_RS12845	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS55_RS12850	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS55_RS12855	COG0567	Dehydrogenase, E1 component
GQS55_RS12860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQS55_RS12865	COG1053	succinate dehydrogenase
GQS55_RS12870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GQS55_RS12875	COG2009	succinate dehydrogenase
GQS55_RS12880	COG0372	Belongs to the citrate synthase family
GQS55_RS12885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GQS55_RS12900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS55_RS12905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQS55_RS12910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQS55_RS12915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQS55_RS12920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQS55_RS12925	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GQS55_RS12930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GQS55_RS12940	COG0534	Mate efflux family protein
GQS55_RS12955	COG1396	sequence-specific DNA binding
GQS55_RS12960	COG3550	peptidyl-serine autophosphorylation
GQS55_RS12980	COG1061	Type III restriction enzyme res subunit
GQS55_RS13005	COG0210	DNA helicase
GQS55_RS13020	COG1136	(ABC) transporter
GQS55_RS13025	COG2177	Part of the ABC transporter FtsEX involved in
GQS55_RS13030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS55_RS13065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GQS55_RS13095	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS13105	COG2186	Transcriptional regulator
GQS55_RS13115	COG4771	TonB-dependent receptor
GQS55_RS13125	COG3852	Histidine kinase
GQS55_RS13135	COG0577	efflux transmembrane transporter activity
GQS55_RS13135	COG1136	(ABC) transporter
GQS55_RS13175	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS55_RS13175	COG1024	Enoyl-CoA hydratase
GQS55_RS13180	COG0183	Belongs to the thiolase family
GQS55_RS13185	COG0714	Associated with various cellular activities
GQS55_RS13205	COG2304	oxidoreductase activity
GQS55_RS13215	COG1595	DNA-templated transcription, initiation
GQS55_RS13230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS55_RS13235	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GQS55_RS13240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQS55_RS13250	COG0529	Catalyzes the synthesis of activated sulfate
GQS55_RS13255	COG0471	metal ion transport
GQS55_RS13255	COG3273	potassium ion transport
GQS55_RS13260	COG2895	sulfate adenylyltransferase (ATP) activity
GQS55_RS13265	COG0175	sulfate reduction
GQS55_RS13275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GQS55_RS13320	COG1187	pseudouridine synthase activity
GQS55_RS13325	COG2850	peptidyl-arginine hydroxylation
GQS55_RS13330	COG2201	protein-glutamate methylesterase activity
GQS55_RS13335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GQS55_RS13335	COG1116	anion transmembrane transporter activity
GQS55_RS13340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GQS55_RS13345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQS55_RS13350	COG1116	anion transmembrane transporter activity
GQS55_RS13360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS55_RS13360	COG2146	nitrite reductase [NAD(P)H] activity
GQS55_RS13370	COG0243	molybdopterin cofactor binding
GQS55_RS13375	COG2835	tetraacyldisaccharide 4'-kinase activity
GQS55_RS13385	COG1132	(ABC) transporter
GQS55_RS13390	COG2333	competence protein COMEC
GQS55_RS13390	COG0658	competence protein
GQS55_RS13400	COG2255	four-way junction helicase activity
GQS55_RS13405	COG0632	four-way junction helicase activity
GQS55_RS13410	COG0673	inositol 2-dehydrogenase activity
GQS55_RS13415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQS55_RS13420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQS55_RS13425	COG2226	methyltransferase
GQS55_RS13430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQS55_RS13455	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GQS55_RS13490	COG1252	NADH dehydrogenase
GQS55_RS13505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQS55_RS13515	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS55_RS13520	COG0022	dehydrogenase e1 component
GQS55_RS13525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS55_RS13530	COG0667	Aldo Keto reductase
GQS55_RS13535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQS55_RS13545	COG0033	Phosphoglucomutase
GQS55_RS13555	COG0596	Alpha beta hydrolase
GQS55_RS13570	COG0716	FMN binding
GQS55_RS13575	COG0735	belongs to the Fur family
GQS55_RS13590	COG2824	Alkylphosphonate utilization operon protein PhnA
GQS55_RS13595	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GQS55_RS13605	COG0825	malonyl-CoA metabolic process
GQS55_RS13610	COG0587	DNA-directed DNA polymerase activity
GQS55_RS13615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQS55_RS13620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQS55_RS13625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQS55_RS13630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQS55_RS13650	COG0750	zinc metalloprotease
GQS55_RS13655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GQS55_RS13660	COG0575	Belongs to the CDS family
GQS55_RS13665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQS55_RS13670	COG0233	cytoplasmic translational termination
GQS55_RS13675	COG0528	UMP kinase activity
GQS55_RS13685	COG0052	Belongs to the universal ribosomal protein uS2 family
GQS55_RS13695	COG0024	Methionine aminopeptidase
GQS55_RS13700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GQS55_RS13705	COG2171	N-acyltransferase activity
GQS55_RS13715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQS55_RS13720	COG0494	nUDIX hydrolase
GQS55_RS13725	COG1760	l-serine dehydratase
GQS55_RS13730	COG0583	DNA-binding transcription factor activity
GQS55_RS13745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQS55_RS13750	COG0010	Belongs to the arginase family
GQS55_RS13760	COG1301	dicarboxylic acid transport
GQS55_RS13765	COG0616	signal peptide processing
GQS55_RS13770	COG2366	antibiotic biosynthetic process
GQS55_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS13785	COG0318	PFAM AMP-dependent synthetase and ligase
GQS55_RS13790	COG0596	Alpha beta hydrolase
GQS55_RS13805	COG1214	PFAM Peptidase M22, glycoprotease
GQS55_RS13810	COG1199	ATP-dependent helicase activity
GQS55_RS13825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQS55_RS13840	COG0131	Imidazoleglycerol-phosphate dehydratase
GQS55_RS13840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GQS55_RS13845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQS55_RS13850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQS55_RS13855	COG0107	imidazoleglycerol-phosphate synthase activity
GQS55_RS13860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQS55_RS13860	COG0140	phosphoribosyl-ATP diphosphatase activity
GQS55_RS13865	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GQS55_RS13870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQS55_RS13870	COG0517	IMP dehydrogenase activity
GQS55_RS13880	COG2153	protein acetylation
GQS55_RS13885	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GQS55_RS13890	COG0563	adenylate kinase activity
GQS55_RS13895	COG0326	Molecular chaperone. Has ATPase activity
GQS55_RS13900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQS55_RS13910	COG3101	peptidyl-lysine hydroxylation
GQS55_RS13920	COG2212	antiporter activity
GQS55_RS13930	COG0651	ATP synthesis coupled electron transport
GQS55_RS13935	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS55_RS13940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS55_RS13940	COG2111	Na H antiporter
GQS55_RS13950	COG3064	Membrane
GQS55_RS13960	COG0745	RESPONSE REGULATOR receiver
GQS55_RS13980	COG0443	Heat shock 70 kDa protein
GQS55_RS13985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQS55_RS13990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS55_RS13995	COG0497	DNA recombination
GQS55_RS14000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQS55_RS14005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQS55_RS14015	COG2197	response regulator
GQS55_RS14020	COG0322	excinuclease ABC activity
GQS55_RS14095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GQS55_RS14125	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GQS55_RS14130	COG2885	chlorophyll binding
GQS55_RS14135	COG0823	Involved in the tonB-independent uptake of proteins
GQS55_RS14150	COG0811	peptide transport
GQS55_RS14155	COG0824	Thioesterase
GQS55_RS14160	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQS55_RS14195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQS55_RS14200	COG0505	Belongs to the CarA family
GQS55_RS14205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQS55_RS14215	COG0545	Peptidyl-prolyl cis-trans isomerase
GQS55_RS14230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQS55_RS14255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GQS55_RS14260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQS55_RS14265	COG0166	Belongs to the GPI family
GQS55_RS14270	COG1609	Transcriptional regulator
GQS55_RS14285	COG1842	Phage shock protein A
GQS55_RS14290	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GQS55_RS14295	COG0747	negative chemotaxis
GQS55_RS14300	COG4168	peptide transport system, permease
GQS55_RS14305	COG4171	peptide transport system, permease
GQS55_RS14320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQS55_RS14325	COG0776	regulation of translation
GQS55_RS14335	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQS55_RS14340	COG0740	serine-type endopeptidase activity
GQS55_RS14345	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQS55_RS14370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQS55_RS14375	COG0215	cysteine-tRNA ligase activity
GQS55_RS14380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQS55_RS14395	COG1858	cytochrome C peroxidase
GQS55_RS14425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GQS55_RS14430	COG1286	toxin biosynthetic process
GQS55_RS14440	COG0285	dihydrofolate synthase activity
GQS55_RS14445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQS55_RS14450	COG0101	tRNA pseudouridine synthase activity
GQS55_RS14470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQS55_RS14500	COG2204	response regulator
GQS55_RS14510	COG2205	protein histidine kinase activity
GQS55_RS14540	COG0598	Magnesium transport protein CorA
GQS55_RS14555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS55_RS14575	COG2222	sugar isomerase
GQS55_RS14590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQS55_RS14595	COG3345	alpha-galactosidase
GQS55_RS14615	COG0166	Belongs to the GPI family
GQS55_RS14625	COG3345	alpha-galactosidase
GQS55_RS14630	COG1349	DNA-binding transcription factor activity
GQS55_RS14650	COG0583	DNA-binding transcription factor activity
GQS55_RS14655	COG0189	ligase activity
GQS55_RS14665	COG0189	ligase activity
GQS55_RS14665	COG4067	protein conserved in archaea
GQS55_RS14670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GQS55_RS14670	COG3264	Mechanosensitive ion channel
GQS55_RS14680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQS55_RS14685	COG0701	Predicted permease
GQS55_RS14695	COG4536	flavin adenine dinucleotide binding
GQS55_RS14740	COG0583	DNA-binding transcription factor activity
GQS55_RS14755	COG4771	TonB-dependent receptor
GQS55_RS14765	COG2918	glutathione biosynthetic process
GQS55_RS14770	COG0612	Peptidase, M16
GQS55_RS14775	COG0564	pseudouridine synthase activity
GQS55_RS14780	COG0733	neurotransmitter:sodium symporter activity
GQS55_RS14785	COG3706	GGDEF domain
GQS55_RS14790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQS55_RS14800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GQS55_RS14805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GQS55_RS14810	COG0716	FMN binding
GQS55_RS14815	COG0513	Belongs to the DEAD box helicase family
GQS55_RS14835	COG0513	Belongs to the DEAD box helicase family
GQS55_RS14845	COG3335	DDE superfamily endonuclease
GQS55_RS14885	COG3022	response to hydroperoxide
GQS55_RS14890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQS55_RS14910	COG0564	pseudouridine synthase activity
GQS55_RS14935	COG4807	Protein conserved in bacteria
GQS55_RS14950	COG0848	biopolymer transport protein
GQS55_RS14955	COG0811	peptide transport
GQS55_RS14960	COG0811	peptide transport
GQS55_RS14975	COG1671	Belongs to the UPF0178 family
GQS55_RS14985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS55_RS14990	COG4286	Uncharacterised protein family (UPF0160)
GQS55_RS15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS55_RS15005	COG0733	neurotransmitter:sodium symporter activity
GQS55_RS15015	COG2921	Belongs to the UPF0250 family
GQS55_RS15020	COG0321	lipoyl(octanoyl) transferase activity
GQS55_RS15025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQS55_RS15050	COG2252	PERMEase
GQS55_RS15055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS55_RS15075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GQS55_RS15085	COG1309	transcriptional regulator
GQS55_RS15095	COG0402	S-adenosylhomocysteine deaminase activity
GQS55_RS15105	COG2351	hydroxyisourate hydrolase activity
GQS55_RS15115	COG4266	Belongs to the allantoicase family
GQS55_RS15120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS55_RS15130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GQS55_RS15145	COG1067	ATP-dependent peptidase activity
GQS55_RS15150	COG2888	peptidyl-tyrosine sulfation
GQS55_RS15155	COG0495	leucyl-tRNA aminoacylation
GQS55_RS15160	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GQS55_RS15165	COG1466	dna polymerase III delta subunit
GQS55_RS15170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQS55_RS15175	COG0799	negative regulation of ribosome biogenesis
GQS55_RS15180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GQS55_RS15185	COG0768	penicillin binding
GQS55_RS15190	COG0772	Belongs to the SEDS family
GQS55_RS15195	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GQS55_RS15200	COG1686	Belongs to the peptidase S11 family
GQS55_RS15210	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GQS55_RS15215	COG0204	Acyl-transferase
GQS55_RS15225	COG1024	Enoyl-CoA hydratase
GQS55_RS15230	COG0363	glucosamine-6-phosphate deaminase activity
GQS55_RS15235	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GQS55_RS15240	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQS55_RS15245	COG0730	response to heat
GQS55_RS15255	COG0494	nUDIX hydrolase
GQS55_RS15260	COG3066	DNA modification
GQS55_RS15270	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQS55_RS15285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS55_RS15315	COG0488	(ABC) transporter
GQS55_RS15330	COG3228	Belongs to the MtfA family
GQS55_RS15340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS55_RS15345	COG2271	Major facilitator Superfamily
GQS55_RS15365	COG2186	Transcriptional regulator
GQS55_RS15375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GQS55_RS15395	COG0830	nickel cation binding
GQS55_RS15400	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GQS55_RS15415	COG0831	urea catabolic process
GQS55_RS15420	COG0829	nickel cation binding
GQS55_RS15425	COG0410	ABC transporter
GQS55_RS15440	COG0559	Belongs to the binding-protein-dependent transport system permease family
GQS55_RS15455	COG0784	Response regulator, receiver
GQS55_RS15455	COG5002	protein histidine kinase activity
GQS55_RS15455	COG2198	Histidine kinase
GQS55_RS15460	COG0745	RESPONSE REGULATOR receiver
GQS55_RS15485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQS55_RS15490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GQS55_RS15495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQS55_RS15500	COG0745	RESPONSE REGULATOR receiver
GQS55_RS15510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQS55_RS15515	COG3031	protein transport across the cell outer membrane
GQS55_RS15530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQS55_RS15535	COG1459	type II secretion system
GQS55_RS15540	COG2165	general secretion pathway protein
GQS55_RS15560	COG3156	type II secretion system protein K
GQS55_RS15570	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GQS55_RS15580	COG1858	cytochrome C peroxidase
GQS55_RS15600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GQS55_RS15620	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQS55_RS15625	COG3789	protein conserved in bacteria
GQS55_RS15645	COG3025	triphosphatase activity
GQS55_RS15650	COG4991	sh3 domain protein
GQS55_RS15665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQS55_RS15675	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GQS55_RS15680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQS55_RS15685	COG0473	3-isopropylmalate dehydrogenase activity
GQS55_RS15690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GQS55_RS15695	COG0066	3-isopropylmalate dehydratase activity
GQS55_RS15700	COG3409	Peptidoglycan-binding domain 1 protein
GQS55_RS15700	COG3267	Type II secretory pathway component ExeA
GQS55_RS15705	COG0617	tRNA 3'-terminal CCA addition
GQS55_RS15710	COG3530	Putative quorum-sensing-regulated virulence factor
GQS55_RS15725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GQS55_RS15740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQS55_RS15745	COG0157	Belongs to the NadC ModD family
GQS55_RS15760	COG3725	Membrane protein required for beta-lactamase induction
GQS55_RS15765	COG2186	Transcriptional regulator
GQS55_RS15770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GQS55_RS15775	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS55_RS15780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS55_RS15800	COG1049	propionate catabolic process, 2-methylcitrate cycle
GQS55_RS15810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS55_RS15830	COG0542	response to heat
GQS55_RS15840	COG0564	pseudouridine synthase activity
GQS55_RS15845	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQS55_RS15855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQS55_RS15865	COG4969	Belongs to the N-Me-Phe pilin family
GQS55_RS15875	COG4968	Prepilin-type N-terminal cleavage methylation domain
GQS55_RS15900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GQS55_RS15905	COG1047	Peptidyl-prolyl cis-trans
GQS55_RS15915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQS55_RS15920	COG0196	riboflavin kinase activity
GQS55_RS15925	COG0728	peptidoglycan biosynthetic process
GQS55_RS15930	COG0268	Binds directly to 16S ribosomal RNA
GQS55_RS15945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQS55_RS15950	COG0739	heme binding
GQS55_RS15970	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GQS55_RS15975	COG2814	Major facilitator Superfamily
GQS55_RS15980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS55_RS15985	COG0697	spore germination
GQS55_RS15995	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQS55_RS16000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GQS55_RS16005	COG1227	inorganic diphosphatase activity
GQS55_RS16010	COG0183	Belongs to the thiolase family
GQS55_RS16015	COG1024	Enoyl-CoA hydratase
GQS55_RS16015	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQS55_RS16025	COG3300	MHYT domain
GQS55_RS16025	COG5001	Diguanylate cyclase
GQS55_RS16040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS55_RS16090	COG1842	Phage shock protein A
GQS55_RS16100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQS55_RS16120	COG4128	Pfam Zonular occludens toxin
GQS55_RS16180	COG0583	DNA-binding transcription factor activity
GQS55_RS16215	COG1566	PFAM secretion protein HlyD family protein
GQS55_RS16225	COG2996	Protein conserved in bacteria
GQS55_RS16230	COG3706	GGDEF domain
GQS55_RS16245	COG0019	diaminopimelate decarboxylase activity
GQS55_RS16250	COG2171	N-acyltransferase activity
GQS55_RS16255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS55_RS16265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQS55_RS16265	COG4191	Histidine kinase
GQS55_RS16270	COG0745	RESPONSE REGULATOR receiver
GQS55_RS16275	COG2198	Histidine kinase
GQS55_RS16275	COG0784	Response regulator, receiver
GQS55_RS16275	COG5002	protein histidine kinase activity
GQS55_RS16280	COG1469	GTP cyclohydrolase I activity
GQS55_RS16290	COG0493	'glutamate synthase
GQS55_RS16295	COG0069	glutamate synthase activity
GQS55_RS16295	COG0070	glutamate synthase
GQS55_RS16295	COG0067	glutamate synthase
GQS55_RS16300	COG0493	'glutamate synthase
GQS55_RS16305	COG1757	Na H antiporter
GQS55_RS16325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS55_RS16330	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQS55_RS16335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQS55_RS16340	COG0142	geranyltranstransferase activity
GQS55_RS16345	COG4628	conserved protein (DUF2132)
GQS55_RS16355	COG1438	arginine binding
GQS55_RS16360	COG2205	protein histidine kinase activity
GQS55_RS16360	COG0784	Response regulator, receiver
GQS55_RS16360	COG5002	protein histidine kinase activity
GQS55_RS16365	COG1230	cation diffusion facilitator family transporter
GQS55_RS16370	COG1472	Belongs to the glycosyl hydrolase 3 family
GQS55_RS16380	COG3265	gluconokinase activity
GQS55_RS16385	COG3459	Glycosyltransferase 36 associated
GQS55_RS16390	COG2211	Major facilitator Superfamily
GQS55_RS16405	COG1472	Belongs to the glycosyl hydrolase 3 family
GQS55_RS16420	COG2211	Major facilitator Superfamily
GQS55_RS16435	COG0735	belongs to the Fur family
GQS55_RS16450	COG0653	protein targeting
GQS55_RS16455	COG0523	cobalamin synthesis protein
GQS55_RS16465	COG1136	(ABC) transporter
GQS55_RS16485	COG0789	Transcriptional regulator
GQS55_RS16490	COG2137	regulation of response to DNA damage stimulus
GQS55_RS16495	COG1228	amidohydrolase
GQS55_RS16505	COG3344	reverse transcriptase
GQS55_RS16550	COG0542	response to heat
GQS55_RS16580	COG0582	viral genome integration into host DNA
GQS55_RS16590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQS55_RS16605	COG4232	protein-disulfide reductase activity
GQS55_RS16625	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQS55_RS16630	COG0511	ligase activity, forming carbon-carbon bonds
GQS55_RS16635	COG0439	Biotin carboxylase
GQS55_RS16650	COG4772	TonB-dependent receptor
GQS55_RS16660	COG0535	radical SAM domain protein
GQS55_RS16670	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GQS55_RS16695	COG2217	Heavy metal translocating P-type atpase
GQS55_RS16710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQS55_RS16720	COG0359	binds to the 23S rRNA
GQS55_RS16725	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQS55_RS16730	COG2965	DNA replication, synthesis of RNA primer
GQS55_RS16735	COG0360	Binds together with S18 to 16S ribosomal RNA
GQS55_RS16750	COG1538	Outer membrane efflux protein
GQS55_RS16760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS55_RS16765	COG0557	exoribonuclease II activity
GQS55_RS16770	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GQS55_RS16780	COG3706	GGDEF domain
GQS55_RS16785	COG0316	Belongs to the HesB IscA family
GQS55_RS16790	COG0038	chloride channel
GQS55_RS16800	COG0540	Belongs to the ATCase OTCase family
GQS55_RS16805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQS55_RS16815	COG0303	'Molybdopterin
GQS55_RS16820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS55_RS16825	COG0746	molybdenum cofactor guanylyltransferase activity
GQS55_RS16830	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQS55_RS16840	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GQS55_RS16845	COG0314	molybdopterin synthase activity
GQS55_RS16860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GQS55_RS16865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQS55_RS16870	COG3130	regulation of translation
GQS55_RS16930	COG0514	ATP-dependent DNA helicase (RecQ)
GQS55_RS16985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS55_RS16985	COG0519	Catalyzes the synthesis of GMP from XMP
GQS55_RS16990	COG0517	IMP dehydrogenase activity
GQS55_RS16990	COG0516	GMP reductase activity
GQS55_RS16995	COG1570	exodeoxyribonuclease VII activity
GQS55_RS17005	COG1160	GTP binding
GQS55_RS17010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQS55_RS17015	COG2976	Protein conserved in bacteria
GQS55_RS17020	COG0124	histidyl-tRNA synthetase
GQS55_RS17025	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQS55_RS17040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GQS55_RS17045	COG0105	UTP biosynthetic process
GQS55_RS17050	COG0659	secondary active sulfate transmembrane transporter activity
GQS55_RS17055	COG0318	PFAM AMP-dependent synthetase and ligase
GQS55_RS17070	COG0281	malic enzyme
GQS55_RS17085	COG1522	sequence-specific DNA binding
GQS55_RS17090	COG1490	D-aminoacyl-tRNA deacylase activity
GQS55_RS17095	COG1295	ribonuclease BN
GQS55_RS17110	COG0174	glutamine synthetase
GQS55_RS17120	COG3852	Histidine kinase
GQS55_RS17125	COG2204	response regulator
GQS55_RS17135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GQS55_RS17140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS55_RS17145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQS55_RS17150	COG0049	tRNA binding
GQS55_RS17155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQS55_RS17160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS55_RS17165	COG0085	RNA polymerase activity
GQS55_RS17175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQS55_RS17180	COG0081	regulation of translation
GQS55_RS17185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQS55_RS17190	COG0250	Participates in transcription elongation, termination and antitermination
GQS55_RS17195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GQS55_RS17205	COG3263	regulation of cellular component size
GQS55_RS17210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS55_RS17290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS55_RS17305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS55_RS17315	COG0281	malic enzyme
GQS55_RS17320	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQS55_RS17325	COG0255	Belongs to the universal ribosomal protein uL29 family
GQS55_RS17330	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQS55_RS17335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQS55_RS17340	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQS55_RS17345	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQS55_RS17350	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQS55_RS17355	COG0089	rRNA binding
GQS55_RS17360	COG0088	Forms part of the polypeptide exit tunnel
GQS55_RS17365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQS55_RS17370	COG0051	transcription antitermination factor activity, RNA binding
GQS55_RS17375	COG0318	PFAM AMP-dependent synthetase and ligase
GQS55_RS17380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQS55_RS17385	COG2207	Transcriptional regulator
GQS55_RS17390	COG0673	inositol 2-dehydrogenase activity
GQS55_RS17410	COG0644	oxidoreductase
GQS55_RS17420	COG0151	Belongs to the GarS family
GQS55_RS17430	COG0138	bifunctional purine biosynthesis protein purh
GQS55_RS17435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GQS55_RS17440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQS55_RS17465	COG2264	protein methyltransferase activity
GQS55_RS17470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GQS55_RS17475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQS55_RS17475	COG1648	precorrin-2 dehydrogenase activity
GQS55_RS17500	COG3769	mannosylglycerate metabolic process
GQS55_RS17505	COG1215	transferase activity, transferring glycosyl groups
GQS55_RS17570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS55_RS17575	COG2315	Protein conserved in bacteria
GQS55_RS17585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS55_RS17595	COG0180	Tryptophanyl-tRNA synthetase
GQS55_RS17600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQS55_RS17615	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GQS55_RS17625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GQS55_RS17630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQS55_RS17660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GQS55_RS17670	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GQS55_RS17670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQS55_RS17680	COG0137	argininosuccinate synthase activity
GQS55_RS17685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQS55_RS17690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQS55_RS17730	COG0460	homoserine dehydrogenase
GQS55_RS17730	COG0527	aspartate kinase activity
GQS55_RS17735	COG0626	cystathionine gamma-synthase activity
GQS55_RS17745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQS55_RS17765	COG0545	Peptidyl-prolyl cis-trans isomerase
GQS55_RS17800	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS17825	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS17830	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS17845	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS17855	COG2944	sequence-specific DNA binding
GQS55_RS17865	COG3547	Transposase (IS116 IS110 IS902 family)
GQS55_RS17960	COG1028	Short-chain dehydrogenase reductase Sdr
GQS55_RS18000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQS55_RS18005	COG4136	ATPase activity
GQS55_RS18015	COG4134	Bacterial extracellular solute-binding protein
GQS55_RS18040	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GQS55_RS18045	COG0488	(ABC) transporter
GQS55_RS18065	COG1218	3'(2'),5'-bisphosphate nucleotidase
GQS55_RS18070	COG0494	nUDIX hydrolase
GQS55_RS18075	COG1011	Hydrolase
GQS55_RS18085	COG0701	Predicted permease
GQS55_RS18110	COG0840	transmembrane signaling receptor activity
GQS55_RS18115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GQS55_RS18125	COG1233	COG1233 Phytoene dehydrogenase and related
GQS55_RS18130	COG4221	oxidoreductase activity
GQS55_RS18140	COG0415	Belongs to the DNA photolyase family
GQS55_RS18150	COG3806	Anti-sigma factor
GQS55_RS18155	COG1595	DNA-templated transcription, initiation
GQS55_RS18190	COG1090	epimerase
GQS55_RS18195	COG1785	Belongs to the alkaline phosphatase family
GQS55_RS18200	COG1785	Belongs to the alkaline phosphatase family
GQS55_RS18210	COG0778	Nitroreductase
GQS55_RS18235	COG0405	Gamma-glutamyltransferase
GQS55_RS18240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQS55_RS18250	COG3078	GTPase activator activity
GQS55_RS18255	COG0346	lactoylglutathione lyase activity
GQS55_RS18270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GQS55_RS18270	COG0678	peroxiredoxin activity
GQS55_RS18295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GQS55_RS18335	COG0745	RESPONSE REGULATOR receiver
GQS55_RS18340	COG2205	protein histidine kinase activity
GQS55_RS18345	COG4772	TonB-dependent receptor
GQS55_RS18350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQS55_RS18355	COG0330	HflC and HflK could
GQS55_RS18360	COG0330	HflC and HflK could
GQS55_RS18365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQS55_RS18370	COG1923	regulation of RNA biosynthetic process
GQS55_RS18375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQS55_RS18385	COG0860	N-Acetylmuramoyl-L-alanine amidase
GQS55_RS18390	COG0802	atpase or kinase
GQS55_RS18405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GQS55_RS18410	COG1162	GTPase activity
GQS55_RS18415	COG0688	phosphatidylethanolamine metabolic process
GQS55_RS18435	COG0745	RESPONSE REGULATOR receiver
GQS55_RS18440	COG2205	protein histidine kinase activity
GQS55_RS18450	COG3706	GGDEF domain
GQS55_RS18450	COG0745	RESPONSE REGULATOR receiver
GQS55_RS18455	COG2205	protein histidine kinase activity
GQS55_RS18460	COG0745	RESPONSE REGULATOR receiver
GQS55_RS18495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQS55_RS18525	COG0517	IMP dehydrogenase activity
GQS55_RS18535	COG1561	YicC-like family, N-terminal region
GQS55_RS18540	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GQS55_RS18555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQS55_RS18560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQS55_RS18575	COG0596	Alpha beta hydrolase
GQS55_RS18580	COG1040	competence protein
GQS55_RS18590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GQS55_RS18590	COG0316	Belongs to the HesB IscA family
GQS55_RS18610	COG1999	signal sequence binding
GQS55_RS18615	COG0109	protoheme IX farnesyltransferase activity
GQS55_RS18640	COG1845	cytochrome c oxidase, subunit III
GQS55_RS18645	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GQS55_RS18650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQS55_RS18655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQS55_RS18660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQS55_RS18670	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GQS55_RS18680	COG2165	general secretion pathway protein
GQS55_RS18685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQS55_RS18695	COG3031	protein transport across the cell outer membrane
GQS55_RS18700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GQS55_RS18705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GQS55_RS18710	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GQS55_RS18720	COG0745	RESPONSE REGULATOR receiver
GQS55_RS18730	COG0668	transmembrane transport
GQS55_RS18755	COG1115	amino acid carrier protein
GQS55_RS18770	COG3706	GGDEF domain
GQS55_RS18775	COG2937	Belongs to the GPAT DAPAT family
GQS55_RS18780	COG2854	intermembrane phospholipid transfer
GQS55_RS18800	COG1309	transcriptional regulator
GQS55_RS18805	COG0604	alcohol dehydrogenase
GQS55_RS18815	COG4585	Histidine kinase
GQS55_RS18820	COG2197	response regulator
GQS55_RS18825	COG5001	Diguanylate cyclase
GQS55_RS18845	COG1473	amidohydrolase
GQS55_RS18860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GQS55_RS18865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQS55_RS18885	COG0705	Rhomboid family
GQS55_RS18890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS55_RS18895	COG1063	alcohol dehydrogenase
GQS55_RS18905	COG1519	Transferase
GQS55_RS18910	COG3642	lipopolysaccharide core region biosynthetic process
GQS55_RS18925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQS55_RS18935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQS55_RS18945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQS55_RS18950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQS55_RS18955	COG2003	Belongs to the UPF0758 family
GQS55_RS18960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GQS55_RS18965	COG1309	transcriptional regulator
GQS55_RS18970	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQS55_RS18980	COG3850	Histidine kinase
GQS55_RS18980	COG3437	response regulator, receiver
GQS55_RS18980	COG2205	protein histidine kinase activity
GQS55_RS18980	COG4999	Histidine kinase
GQS55_RS18985	COG1629	transport
GQS55_RS18985	COG4774	siderophore transport
GQS55_RS19005	COG2201	protein-glutamate methylesterase activity
GQS55_RS19020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS55_RS19040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQS55_RS19055	COG0840	transmembrane signaling receptor activity
GQS55_RS19060	COG2183	response to ionizing radiation
GQS55_RS19070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GQS55_RS19085	COG1448	Aminotransferase
GQS55_RS19090	COG0194	GDP metabolic process
GQS55_RS19095	COG1758	RNA polymerase activity
GQS55_RS19100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GQS55_RS19110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQS55_RS19115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQS55_RS19140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQS55_RS19155	COG0742	ribosomal rna small subunit methyltransferase
GQS55_RS19175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQS55_RS19190	COG0583	DNA-binding transcription factor activity
GQS55_RS19200	COG0004	ammonium transporteR
GQS55_RS19205	COG0163	prenyltransferase activity
GQS55_RS19210	COG1528	Iron-storage protein
GQS55_RS19220	COG2081	HI0933 family
GQS55_RS19290	COG2205	protein histidine kinase activity
GQS55_RS19290	COG2198	Histidine kinase
GQS55_RS19290	COG0784	Response regulator, receiver
GQS55_RS19295	COG3437	response regulator, receiver
GQS55_RS19300	COG1309	transcriptional regulator
GQS55_RS19360	COG0625	glutathione transferase activity
GQS55_RS19365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQS55_RS19370	COG2177	Part of the ABC transporter FtsEX involved in
GQS55_RS19375	COG2884	Cell division ATP-binding protein ftsE
GQS55_RS19380	COG0552	protein localization to endoplasmic reticulum
GQS55_RS19385	COG0742	ribosomal rna small subunit methyltransferase
GQS55_RS19390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQS55_RS19395	COG3068	Protein conserved in bacteria
GQS55_RS19410	COG0583	DNA-binding transcription factor activity
GQS55_RS19430	COG4771	TonB-dependent receptor
GQS55_RS19455	COG0523	cobalamin synthesis protein
GQS55_RS19475	COG2205	protein histidine kinase activity
GQS55_RS19480	COG0745	RESPONSE REGULATOR receiver
GQS55_RS19490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQS55_RS19525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQS55_RS19535	COG0823	Involved in the tonB-independent uptake of proteins
GQS55_RS19550	COG0625	glutathione transferase activity
GQS55_RS19555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQS55_RS19560	COG1349	DNA-binding transcription factor activity
GQS55_RS19570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQS55_RS19585	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GQS55_RS19615	COG0406	alpha-ribazole phosphatase activity
GQS55_RS19630	COG4206	TonB-dependent receptor
GQS55_RS19645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GQS55_RS19665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQS55_RS19670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQS55_RS19675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQS55_RS19680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQS55_RS19685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQS55_RS19700	COG3312	ion transport
GQS55_RS19705	COG1475	DNA binding
GQS55_RS19710	COG1192	Involved in chromosome partitioning
GQS55_RS19715	COG0357	Ribosomal RNA small subunit methyltransferase G
GQS55_RS19720	COG0445	tRNA wobble uridine modification
GQS55_RS19725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GQS55_RS19740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GQS55_RS19745	COG0706	membrane insertase activity
GQS55_RS19750	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQS55_RS19755	COG0594	ribonuclease P activity
GQS55_RS19760	COG0230	Belongs to the bacterial ribosomal protein bL34 family