locus-tag	class	description
F0Q04_RS00025	ENOG4105D7Z	glutathione synthase
F0Q04_RS00030	ENOG4105DKK	Benzoate
F0Q04_RS00035	ENOG4105DFH	Transport of potassium into the cell (By similarity)
F0Q04_RS00045	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F0Q04_RS00050	ENOG4105C1A	potassium transporter peripheral membrane
F0Q04_RS00055	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
F0Q04_RS00065	ENOG4105C8V	SAICAR synthetase
F0Q04_RS00070	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
F0Q04_RS00075	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
F0Q04_RS00080	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
F0Q04_RS00095	ENOG41090R7	Ferric uptake
F0Q04_RS00100	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0Q04_RS00105	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F0Q04_RS00130	ENOG4105CUY	Mechanosensitive ion channel
F0Q04_RS00135	ENOG4105C8T	Leucyl-tRNA synthetase
F0Q04_RS00170	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
F0Q04_RS00180	ENOG4105DND	Transcriptional regulator
F0Q04_RS00185	ENOG4105DZG	Dehydrogenase
F0Q04_RS00200	ENOG4106NZI	LysR family Transcriptional regulator
F0Q04_RS00230	ENOG4107R7Y	intracellular protease Pfpi family
F0Q04_RS00240	ENOG4105D01	(LipO)protein
F0Q04_RS00245	ENOG41060WC	Enoyl-CoA hydratase
F0Q04_RS00250	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS00255	ENOG4105ECQ	AraC Family Transcriptional Regulator
F0Q04_RS00270	ENOG4105D05	Receptor
F0Q04_RS00275	ENOG4105D05	Receptor
F0Q04_RS00280	ENOG4106BRA	Membrane
F0Q04_RS00290	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
F0Q04_RS00305	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0Q04_RS00315	ENOG4105DFA	alanine racemase domain protein
F0Q04_RS00320	ENOG4105CZX	twitching motility protein
F0Q04_RS00330	ENOG4105CZX	twitching motility protein
F0Q04_RS00335	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F0Q04_RS00340	ENOG4105W4M	Transport-associated protein
F0Q04_RS00345	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F0Q04_RS00350	ENOG41082RQ	UPF0102 protein
F0Q04_RS00360	ENOG4105R8A	Heat shock protein
F0Q04_RS00365	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F0Q04_RS00420	ENOG4108KU3	Integrase
F0Q04_RS00480	ENOG4105K89	arsenate reductase
F0Q04_RS00485	ENOG4105CAU	Arsenical resistance protein, ArsH
F0Q04_RS00505	ENOG4105ES5	Histidine kinase
F0Q04_RS00515	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F0Q04_RS00520	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0Q04_RS00525	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0Q04_RS00530	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
F0Q04_RS00535	ENOG4108VZM	50s ribosomal protein L10
F0Q04_RS00540	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F0Q04_RS00545	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F0Q04_RS00555	ENOG4105PM1	preprotein translocase subunit SecE
F0Q04_RS00565	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F0Q04_RS00595	ENOG4105C59	p-type ATPase
F0Q04_RS00615	ENOG4105E3B	Multicopper oxidase
F0Q04_RS00625	ENOG4105GR3	Histidine kinase
F0Q04_RS00680	ENOG4108NF7	phage-type endonuclease
F0Q04_RS00695	ENOG410679B	prophage CP4-57 regulatory protein alpA
F0Q04_RS00700	ENOG4108P8R	
F0Q04_RS00705	ENOG4105H5P	transposase
F0Q04_RS00730	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F0Q04_RS00735	ENOG4105BZS	acriflavin resistance protein
F0Q04_RS00740	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F0Q04_RS00745	ENOG4105MPD	Cytochrome
F0Q04_RS00775	ENOG4105N80	Ferric uptake regulator, Fur family
F0Q04_RS00780	ENOG41090KI	Outer membrane porin
F0Q04_RS00790	ENOG4105E0A	ABC, transporter
F0Q04_RS00795	ENOG4105EHG	Permease protein
F0Q04_RS00800	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
F0Q04_RS00810	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F0Q04_RS00815	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F0Q04_RS00820	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F0Q04_RS00825	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F0Q04_RS00830	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0Q04_RS00835	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0Q04_RS00840	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0Q04_RS00845	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
F0Q04_RS00855	ENOG4108Z43	UPF0250 protein
F0Q04_RS00860	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F0Q04_RS00865	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F0Q04_RS00880	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
F0Q04_RS00885	ENOG41080Z8	PHOSPHOCARRIER protein
F0Q04_RS00900	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0Q04_RS00915	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
F0Q04_RS00920	ENOG41084PQ	50s ribosomal protein l29
F0Q04_RS00925	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F0Q04_RS00930	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
F0Q04_RS00935	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F0Q04_RS00940	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F0Q04_RS00945	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0Q04_RS00950	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F0Q04_RS00955	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F0Q04_RS00960	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F0Q04_RS00965	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F0Q04_RS00970	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F0Q04_RS00975	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F0Q04_RS00980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F0Q04_RS00985	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
F0Q04_RS00990	ENOG4105DZ1	carboxypeptidase
F0Q04_RS00995	ENOG4105DHZ	alpha beta
F0Q04_RS01010	ENOG4108YXA	Membrane
F0Q04_RS01015	ENOG4105D52	delta-aminolevulinic acid dehydratase
F0Q04_RS01020	ENOG4105D7N	magnesium and cobalt transport protein CorA
F0Q04_RS01025	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
F0Q04_RS01035	ENOG4105C2C	drug resistance transporter, Bcr CflA
F0Q04_RS01045	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
F0Q04_RS01050	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F0Q04_RS01055	ENOG4105EB3	Histidine kinase
F0Q04_RS01060	ENOG4105CT7	inner membrane cred family protein
F0Q04_RS01085	ENOG4105DHJ	ABC, transporter
F0Q04_RS01105	ENOG4105CJN	penicillin-binding protein
F0Q04_RS01125	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS01130	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS01135	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS01205	ENOG4108JQ1	Dehydrogenase
F0Q04_RS01210	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0Q04_RS01230	ENOG41068WN	
F0Q04_RS01235	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0Q04_RS01245	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
F0Q04_RS01250	ENOG4105CGK	Exodeoxyribonuclease III
F0Q04_RS01260	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F0Q04_RS01265	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F0Q04_RS01270	ENOG41082W1	Cupin 2, conserved barrel domain protein
F0Q04_RS01280	ENOG4105C5X	domain protein
F0Q04_RS01285	ENOG4107RNH	Outer membrane receptor FepA
F0Q04_RS01295	ENOG4105NIV	Esterase
F0Q04_RS01305	ENOG4105D0M	Protease HtpX homolog
F0Q04_RS01340	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
F0Q04_RS01365	ENOG4105EYM	Major Facilitator superfamily
F0Q04_RS01375	ENOG4105E0F	Histidine kinase
F0Q04_RS01380	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
F0Q04_RS01385	ENOG4108RVA	ribokinase
F0Q04_RS01390	ENOG4105ETE	Transcriptional regulator (LacI family
F0Q04_RS01395	ENOG4105CNN	ABC, transporter
F0Q04_RS01400	ENOG4105C2J	ABC transporter
F0Q04_RS01405	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
F0Q04_RS01410	ENOG4105CBP	Major Facilitator
F0Q04_RS01415	ENOG4105EGI	Transcriptional regulator
F0Q04_RS01420	ENOG4107QWG	2-Nitropropane dioxygenase
F0Q04_RS01425	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
F0Q04_RS01435	ENOG4105PF3	O-Antigen polymerase
F0Q04_RS01455	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F0Q04_RS01470	ENOG4105CPC	Aldo Keto reductase
F0Q04_RS01480	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F0Q04_RS01485	ENOG4108K3A	Glutathione S-transferase
F0Q04_RS01495	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS01505	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS01510	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F0Q04_RS01525	ENOG4107XI7	Tetr family transcriptional regulator
F0Q04_RS01535	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F0Q04_RS01540	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
F0Q04_RS01550	ENOG4108V06	Glutathione peroxidase
F0Q04_RS01560	ENOG4105CHR	reductase
F0Q04_RS01610	ENOG4105G3Z	GntR family transcriptional regulator
F0Q04_RS01625	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0Q04_RS01630	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
F0Q04_RS01635	ENOG4105EU8	FAD linked oxidase domain protein
F0Q04_RS01645	ENOG4108XM1	transcriptional regulator AsnC family
F0Q04_RS01650	ENOG4105C3J	Cysteine desulfurase
F0Q04_RS01655	ENOG4105BZU	Histidine kinase
F0Q04_RS01660	ENOG4108YZA	Nitrogen regulatory protein pii
F0Q04_RS01670	ENOG4105C0P	Mg chelatase subunit ChlI
F0Q04_RS01680	ENOG4105C0Z	ABC transporter
F0Q04_RS01685	ENOG4108IV0	ABC, transporter
F0Q04_RS01690	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS01695	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
F0Q04_RS01725	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS01735	ENOG4105C3U	ABC transporter
F0Q04_RS01740	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS01745	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS01750	ENOG4105E1J	oxidoreductase
F0Q04_RS01760	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F0Q04_RS01790	ENOG4105CQB	FAD linked oxidase domain protein
F0Q04_RS01800	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS01805	ENOG4105F38	ABC transporter, permease
F0Q04_RS01810	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0Q04_RS01835	ENOG4105DP0	ferredoxin-NADP reductase
F0Q04_RS01845	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
F0Q04_RS01850	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F0Q04_RS01855	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0Q04_RS01860	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
F0Q04_RS01865	ENOG41068KF	Universal stress protein
F0Q04_RS01885	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
F0Q04_RS01895	ENOG4108VP3	Lysine exporter protein (LysE YggA)
F0Q04_RS01900	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS01905	ENOG4105WH1	Two component transcriptional regulator luxr family
F0Q04_RS01910	ENOG4105BZU	Histidine kinase
F0Q04_RS01925	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F0Q04_RS01930	ENOG4105D0D	Nitrate reductase 2, gamma subunit
F0Q04_RS01935	ENOG4105R3A	Nitrate reductase
F0Q04_RS01940	ENOG4108IUE	nitrate reductase beta subunit
F0Q04_RS01950	ENOG4105CRU	nitrate reductase, alpha subunit
F0Q04_RS01955	ENOG4105DQQ	Major facilitator superfamily MFS_1
F0Q04_RS01965	ENOG4105C7B	Threonine dehydratase
F0Q04_RS01975	ENOG4105M4H	endoribonuclease L-psp
F0Q04_RS01980	ENOG4105CK2	sodium dicarboxylate symporter
F0Q04_RS01990	ENOG4108R99	pseudouridine synthase
F0Q04_RS02005	ENOG4105VFU	Rna-binding protein
F0Q04_RS02010	ENOG4105CBN	LysR family transcriptional regulator
F0Q04_RS02015	ENOG4105CHR	reductase
F0Q04_RS02025	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
F0Q04_RS02030	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS02035	ENOG4105EAD	ABC transporter
F0Q04_RS02040	ENOG4105EAB	amino acid AbC transporter
F0Q04_RS02050	ENOG4105CAF	HipA N-terminal domain protein
F0Q04_RS02060	ENOG4105C3R	Methionine synthase
F0Q04_RS02065	ENOG4105D6U	Sodium Glutamate Symporter
F0Q04_RS02080	ENOG4105EGS	Mechanosensitive ion channel
F0Q04_RS02085	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F0Q04_RS02110	ENOG4105E39	Enoyl-CoA hydratase
F0Q04_RS02165	ENOG4105D82	Glutamate dehydrogenase
F0Q04_RS02175	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS02210	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS02215	ENOG4108M9J	MaoC like domain protein
F0Q04_RS02220	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
F0Q04_RS02230	ENOG4105CYC	Transferase
F0Q04_RS02235	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS02245	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS02250	ENOG4107ZT5	Thiol disulfide interchange protein
F0Q04_RS02270	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS02275	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS02285	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
F0Q04_RS02290	ENOG4107QMS	site-determining protein
F0Q04_RS02295	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
F0Q04_RS02315	ENOG4105C2W	permease
F0Q04_RS02340	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
F0Q04_RS02355	ENOG4105DZG	Dehydrogenase
F0Q04_RS02360	ENOG4108JIK	carboxylase
F0Q04_RS02365	ENOG4105P4J	Allophanate hydrolase, subunit 1
F0Q04_RS02370	ENOG4105E7W	lamb ycsf family protein
F0Q04_RS02375	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
F0Q04_RS02390	ENOG4107EJG	GntR family transcriptional regulator
F0Q04_RS02395	ENOG4105C3R	Methionine synthase
F0Q04_RS02400	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F0Q04_RS02410	ENOG4107T0D	ABC, transporter
F0Q04_RS02420	ENOG4105CSU	acyl-Coa dehydrogenase
F0Q04_RS02425	ENOG4105EJQ	L-serine dehydratase
F0Q04_RS02435	ENOG4105KA0	thioesterase Superfamily protein
F0Q04_RS02445	ENOG4107RP9	extracellular solute-binding protein, family 3
F0Q04_RS02450	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0Q04_RS02460	ENOG4108WBT	adenosyltransferase
F0Q04_RS02470	ENOG4105CQB	FAD linked oxidase domain protein
F0Q04_RS02485	ENOG4105EW6	flavin reductase domain protein, FMN-binding
F0Q04_RS02500	ENOG4108N8Y	HfaB protein
F0Q04_RS02510	ENOG4105WH1	Two component transcriptional regulator luxr family
F0Q04_RS02515	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
F0Q04_RS02520	ENOG4105BZU	Histidine kinase
F0Q04_RS02530	ENOG4105FA0	parb-like partition protein
F0Q04_RS02540	ENOG4107QJE	Chromosome Partitioning Protein
F0Q04_RS02545	ENOG4108NIW	Leucine export protein LeuE
F0Q04_RS02550	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F0Q04_RS02555	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
F0Q04_RS02560	ENOG4108K3A	Glutathione S-transferase
F0Q04_RS02575	ENOG4105DH7	May be involved in recombination (By similarity)
F0Q04_RS02615	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
F0Q04_RS02630	ENOG4108BUD	transposase
F0Q04_RS02645	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
F0Q04_RS02695	ENOG4108C33	Resolvase
F0Q04_RS02700	ENOG4108R0M	Aminoglycoside
F0Q04_RS02725	ENOG4105DND	Transcriptional regulator
F0Q04_RS02850	ENOG4108BUD	transposase
F0Q04_RS02885	ENOG4108YYQ	gCN5-related N-acetyltransferase
F0Q04_RS02900	ENOG4105BZ4	penicillin-binding protein
F0Q04_RS02980	ENOG4108UKI	Enoyl-CoA hydratase
F0Q04_RS03045	ENOG4108JQ6	ABC transporter
F0Q04_RS03050	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS03080	ENOG4105D7K	pfkb domain protein
F0Q04_RS03090	ENOG4105CDA	abc transporter atp-binding protein
F0Q04_RS03095	ENOG4106PMH	Extracellular solute-binding protein family 3
F0Q04_RS03100	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS03105	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS03110	ENOG4108M60	Transcriptional regulator
F0Q04_RS03115	ENOG4105EVZ	LysR family transcriptional regulator
F0Q04_RS03120	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0Q04_RS03190	ENOG4108RWI	nicotinamidase
F0Q04_RS03225	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F0Q04_RS03230	ENOG4105C26	Dehydrogenase
F0Q04_RS03240	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
F0Q04_RS03250	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS03255	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS03270	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS03275	ENOG4108Z2U	ureidoglycolate hydrolase
F0Q04_RS03290	ENOG4105C6K	Malic enzyme
F0Q04_RS03305	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F0Q04_RS03310	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F0Q04_RS03315	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
F0Q04_RS03320	ENOG4105EHM	Aminoglycoside phosphotransferase
F0Q04_RS03325	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
F0Q04_RS03335	ENOG4105EAB	amino acid AbC transporter
F0Q04_RS03340	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS03345	ENOG4105CDA	abc transporter atp-binding protein
F0Q04_RS03350	ENOG41090B9	response to stress
F0Q04_RS03365	ENOG4105CQB	FAD linked oxidase domain protein
F0Q04_RS03370	ENOG4105BZU	Histidine kinase
F0Q04_RS03380	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F0Q04_RS03400	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F0Q04_RS03410	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F0Q04_RS03425	ENOG4105EUB	pirin domain protein
F0Q04_RS03430	ENOG4105DVT	helicase
F0Q04_RS03445	ENOG4105MFV	ABC-2 type transporter
F0Q04_RS03450	ENOG4105EY8	ABC transporter
F0Q04_RS03460	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
F0Q04_RS03500	ENOG4105CKI	cobalamin synthesis protein
F0Q04_RS03520	ENOG4105CC5	ABC transporter
F0Q04_RS03525	ENOG4105DSE	periplasmic solute binding protein
F0Q04_RS03560	ENOG4105ENE	Histidine kinase
F0Q04_RS03585	ENOG4105DAA	L-lactate
F0Q04_RS03590	ENOG41073TP	transcriptional regulator
F0Q04_RS03600	ENOG4105CXG	d-lactate dehydrogenase
F0Q04_RS03605	ENOG4105DND	Transcriptional regulator
F0Q04_RS03615	ENOG4105D4T	Citrate transporter
F0Q04_RS03635	ENOG4105CSH	Transporter
F0Q04_RS03645	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
F0Q04_RS03680	ENOG4105M4H	endoribonuclease L-psp
F0Q04_RS03685	ENOG4105CJP	fad dependent oxidoreductase
F0Q04_RS03695	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS03705	ENOG4108KSA	LysR family transcriptional regulator
F0Q04_RS03710	ENOG4105EMU	Dehydrogenase
F0Q04_RS03725	ENOG410830R	acetyltransferase
F0Q04_RS03735	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
F0Q04_RS03745	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0Q04_RS03750	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F0Q04_RS03755	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F0Q04_RS03760	ENOG4105VG0	50S ribosomal protein l34
F0Q04_RS03765	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F0Q04_RS03770	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F0Q04_RS03775	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F0Q04_RS03780	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS03785	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
F0Q04_RS03790	ENOG4106F60	Histidine kinase
F0Q04_RS03795	ENOG4105DR4	Methyltransferase
F0Q04_RS03800	ENOG4105CSV	Glutaminase
F0Q04_RS03810	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
F0Q04_RS03815	ENOG4105C2X	Arabinose 5-phosphate isomerase
F0Q04_RS03820	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
F0Q04_RS03830	ENOG4107FW0	short-chain dehydrogenase reductase
F0Q04_RS03835	ENOG4105VFU	Rna-binding protein
F0Q04_RS03840	ENOG4105VFU	Rna-binding protein
F0Q04_RS03850	ENOG4105C26	Dehydrogenase
F0Q04_RS03855	ENOG4105EW9	transcriptional regulator AsnC family
F0Q04_RS03860	ENOG4105DWV	Homoserine O-trans-acetylase
F0Q04_RS03865	ENOG4105DWV	Homoserine O-trans-acetylase
F0Q04_RS03915	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
F0Q04_RS03920	ENOG4105DDW	LysR family Transcriptional regulator
F0Q04_RS03925	ENOG4105BZ7	extracellular solute-binding protein family 1
F0Q04_RS03930	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS03935	ENOG4105F38	ABC transporter, permease
F0Q04_RS03960	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0Q04_RS03970	ENOG4105CYM	Glutathione S-transferase
F0Q04_RS03980	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS03985	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS03995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS04005	ENOG4108JQ7	(ABC) transporter
F0Q04_RS04030	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F0Q04_RS04055	ENOG4105M2Z	protein tyrosine serine phosphatase
F0Q04_RS04075	ENOG4105EFZ	amidohydrolase
F0Q04_RS04085	ENOG4105C2I	pirin domain protein
F0Q04_RS04095	ENOG4108PCN	EamA-like transporter family
F0Q04_RS04105	ENOG4105C2C	drug resistance transporter, Bcr CflA
F0Q04_RS04110	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0Q04_RS04115	ENOG4105EXC	Acyl-transferase
F0Q04_RS04145	ENOG4106IUH	DTW domain containing protein
F0Q04_RS04185	ENOG4105DHQ	Histidine kinase
F0Q04_RS04195	ENOG4108ZK4	sdia-regulated domain-containing protein
F0Q04_RS04205	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F0Q04_RS04210	ENOG4108004	Modulates RecA activity (By similarity)
F0Q04_RS04215	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
F0Q04_RS04225	ENOG4105RPH	Inner membrane protein YddG
F0Q04_RS04235	ENOG4105RPH	Inner membrane protein YddG
F0Q04_RS04240	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
F0Q04_RS04250	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS04255	ENOG4105F38	ABC transporter, permease
F0Q04_RS04260	ENOG4105D38	putrescine abc transporter
F0Q04_RS04275	ENOG4107VFR	oxidoreductase
F0Q04_RS04290	ENOG41090Y2	cytochrome C
F0Q04_RS04295	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
F0Q04_RS04300	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F0Q04_RS04305	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F0Q04_RS04310	ENOG4108ZCF	integral membrane protein
F0Q04_RS04320	ENOG4105KHS	type IV fimbrial pilin protein
F0Q04_RS04330	ENOG4105YWY	
F0Q04_RS04335	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F0Q04_RS04340	ENOG4105ERG	peptidase m48, ste24p
F0Q04_RS04345	ENOG41086DT	Membrane protein of unknown function
F0Q04_RS04355	ENOG4108ZCF	integral membrane protein
F0Q04_RS04365	ENOG4108VWS	Yaeq family
F0Q04_RS04370	ENOG4107QTF	adenylosuccinate lyase
F0Q04_RS04375	ENOG4108U78	Glutathione S-transferase
F0Q04_RS04380	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
F0Q04_RS04395	ENOG4105BZU	Histidine kinase
F0Q04_RS04400	ENOG4108ZXC	Two component transcriptional regulator, luxr family
F0Q04_RS04410	ENOG4105CA3	membrane-bound lytic murein transglycosylase
F0Q04_RS04415	ENOG4105F7P	transcriptional regulator AsnC family
F0Q04_RS04430	ENOG4105VIE	preprotein translocase, subunit YajC
F0Q04_RS04435	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0Q04_RS04440	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0Q04_RS04450	ENOG4105C79	DNA protecting protein DprA
F0Q04_RS04460	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F0Q04_RS04470	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F0Q04_RS04485	ENOG4105BZA	Phosphoglycerate kinase
F0Q04_RS04505	ENOG4105FDR	Membrane
F0Q04_RS04510	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
F0Q04_RS04520	ENOG4108594	Permease of the drug metabolite transporter
F0Q04_RS04525	ENOG4105FC8	fad dependent oxidoreductase
F0Q04_RS04530	ENOG4105D8V	Glucose sorbosone dehydrogenase
F0Q04_RS04540	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F0Q04_RS04545	ENOG4107RDB	Major Facilitator
F0Q04_RS04570	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
F0Q04_RS04585	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F0Q04_RS04600	ENOG4107RAQ	aminopeptidase
F0Q04_RS04605	ENOG4105CA9	Pyruvate kinase
F0Q04_RS04635	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0Q04_RS04640	ENOG4105DHQ	Histidine kinase
F0Q04_RS04645	ENOG4105D2N	Aldolase
F0Q04_RS04650	ENOG4105DC8	reductase
F0Q04_RS04665	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS04680	ENOG4107QUT	magnesium and cobalt transport protein CorA
F0Q04_RS04695	ENOG41072GX	Peptidase M22 Glycoprotease
F0Q04_RS04740	ENOG4105D01	(LipO)protein
F0Q04_RS04745	ENOG4105D01	(LipO)protein
F0Q04_RS04750	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS04755	ENOG4108UMI	ABC transporter, permease
F0Q04_RS04760	ENOG4107T8P	acyl-Coa dehydrogenase
F0Q04_RS04775	ENOG4105D01	(LipO)protein
F0Q04_RS04785	ENOG4105D01	(LipO)protein
F0Q04_RS04790	ENOG4105D01	(LipO)protein
F0Q04_RS04800	ENOG4108UZX	fmn reductase
F0Q04_RS04805	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
F0Q04_RS04820	ENOG4105EQ2	LysR family Transcriptional regulator
F0Q04_RS04825	ENOG4105EUB	pirin domain protein
F0Q04_RS04840	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F0Q04_RS04845	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F0Q04_RS04850	ENOG4105K63	Thioredoxin
F0Q04_RS04865	ENOG4105CQB	FAD linked oxidase domain protein
F0Q04_RS04880	ENOG4105EU0	Major facilitator Superfamily
F0Q04_RS04895	ENOG4105VUF	Transcriptional regulator
F0Q04_RS04925	ENOG4105F1J	Homogentisate 1,2-dioxygenase
F0Q04_RS04945	ENOG4105CH2	amidohydrolase
F0Q04_RS04950	ENOG4108J2R	molybdopterin oxidoreductase
F0Q04_RS04965	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F0Q04_RS04985	ENOG4105BZU	Histidine kinase
F0Q04_RS04990	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
F0Q04_RS05005	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS05010	ENOG4108IV0	ABC, transporter
F0Q04_RS05070	ENOG4105DZS	Phenylacetate-CoA ligase
F0Q04_RS05075	ENOG4108IV0	ABC, transporter
F0Q04_RS05090	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS05095	ENOG4105C0Z	ABC transporter
F0Q04_RS05115	ENOG4105IJJ	transcriptional regulator, crp fnr family
F0Q04_RS05125	ENOG4105FE9	pseudouridine synthase
F0Q04_RS05210	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F0Q04_RS05240	ENOG4105E27	serine threonine protein kinase
F0Q04_RS05245	ENOG4108ZHJ	Organic hydroperoxide resistance protein
F0Q04_RS05250	ENOG4105K56	Transcriptional regulator
F0Q04_RS05255	ENOG4105CNV	Aldolase
F0Q04_RS05265	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0Q04_RS05280	ENOG4105FYV	Amp nucleosidase
F0Q04_RS05285	ENOG4105C1J	atp-dependent rna helicase
F0Q04_RS05295	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
F0Q04_RS05315	ENOG41082F9	transcriptional regulator
F0Q04_RS05320	ENOG4105GR3	Histidine kinase
F0Q04_RS05350	ENOG4105W1Y	Transcriptional regulator
F0Q04_RS05385	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F0Q04_RS05400	ENOG4105EXG	Transcriptional regulator
F0Q04_RS05405	ENOG4105K5X	acetyltransferase
F0Q04_RS05410	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS05415	ENOG4105T38	integral membrane protein
F0Q04_RS05420	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F0Q04_RS05425	ENOG4108RTU	Aldolase
F0Q04_RS05430	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
F0Q04_RS05470	ENOG4106KNT	transcriptional regulator
F0Q04_RS05480	ENOG4105NAE	bifunctional deaminase-reductase domain protein
F0Q04_RS05500	ENOG4106NZI	LysR family Transcriptional regulator
F0Q04_RS05505	ENOG4105EJ9	Membrane
F0Q04_RS05510	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F0Q04_RS05515	ENOG4105C9A	Phoh family
F0Q04_RS05520	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
F0Q04_RS05540	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F0Q04_RS05545	ENOG4105DND	Transcriptional regulator
F0Q04_RS05550	ENOG4105CVJ	phosphoglycerate mutase
F0Q04_RS05560	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F0Q04_RS05595	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS05600	ENOG4105C94	Transporter
F0Q04_RS05615	ENOG4108IJ9	(ABC) transporter
F0Q04_RS05630	ENOG4105DRS	transport system, permease
F0Q04_RS05635	ENOG4105DWY	Agmatine deiminase
F0Q04_RS05640	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS05645	ENOG4108IG5	Transcriptional regulator
F0Q04_RS05650	ENOG4105CIS	alcohol dehydrogenase
F0Q04_RS05685	ENOG4105CYN	Serine protein kinase
F0Q04_RS05690	ENOG4106AKX	UPF0229 protein
F0Q04_RS05695	ENOG4105ED1	spovr family
F0Q04_RS05700	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F0Q04_RS05705	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
F0Q04_RS05710	ENOG4107RP9	extracellular solute-binding protein, family 3
F0Q04_RS05725	ENOG4105DND	Transcriptional regulator
F0Q04_RS05740	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
F0Q04_RS05745	ENOG4105E4C	Lytic transglycosylase catalytic
F0Q04_RS05750	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F0Q04_RS05755	ENOG4107FQ9	ethanolamine ammonia-lyase
F0Q04_RS05760	ENOG4105CPD	ethanolamine ammonia-lyase
F0Q04_RS05765	ENOG4105CUB	amino acid
F0Q04_RS05775	ENOG4105MIR	Phenylalanine 4-monooxygenase
F0Q04_RS05795	ENOG4108YXU	transcriptional regulator AsnC family
F0Q04_RS05805	ENOG4108JU5	Magnesium and cobalt efflux protein
F0Q04_RS05810	ENOG4105CUG	Oligopeptidase b
F0Q04_RS05825	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
F0Q04_RS05840	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
F0Q04_RS05850	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
F0Q04_RS05855	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
F0Q04_RS05860	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
F0Q04_RS05875	ENOG41061MV	Arylsulfatase
F0Q04_RS05890	ENOG4105D7W	serine acetyltransferase
F0Q04_RS05900	ENOG4105ESN	nucleotide-binding protein
F0Q04_RS05905	ENOG4105C9B	Cysteine desulfurase
F0Q04_RS05925	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS05930	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS05935	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
F0Q04_RS05940	ENOG4107YNJ	LysR family Transcriptional regulator
F0Q04_RS05945	ENOG4107RP9	extracellular solute-binding protein, family 3
F0Q04_RS05950	ENOG4105EAD	ABC transporter
F0Q04_RS05955	ENOG4105DRP	amino acid AbC transporter
F0Q04_RS05960	ENOG4105CDA	abc transporter atp-binding protein
F0Q04_RS05965	ENOG4107QXX	ABC transporter
F0Q04_RS05970	ENOG4105EKE	dihydroorotase
F0Q04_RS05980	ENOG4105D0M	Protease HtpX homolog
F0Q04_RS05995	ENOG4105DZ0	fad dependent oxidoreductase
F0Q04_RS06000	ENOG4105EYH	Exonuclease
F0Q04_RS06005	ENOG4107RH8	nuclease SbcCD subunit D
F0Q04_RS06010	ENOG4105EKT	)-iron permease
F0Q04_RS06020	ENOG4105QNF	Outer membrane lipoprotein
F0Q04_RS06025	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
F0Q04_RS06045	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F0Q04_RS06060	ENOG4105R8C	Transcriptional regulator
F0Q04_RS06075	ENOG4105BZ1	(ABC) transporter
F0Q04_RS06085	ENOG4105DSB	aldose 1-epimerase
F0Q04_RS06090	ENOG4108IQI	permease
F0Q04_RS06095	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
F0Q04_RS06110	ENOG4105CKK	Glycosyl transferase, family 2
F0Q04_RS06155	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
F0Q04_RS06160	ENOG41063ZV	
F0Q04_RS06165	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F0Q04_RS06180	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F0Q04_RS06185	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
F0Q04_RS06190	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F0Q04_RS06195	ENOG4105C08	Histidine kinase
F0Q04_RS06205	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
F0Q04_RS06220	ENOG4105QUC	reductase
F0Q04_RS06235	ENOG41081F0	Precorrin-8x methylmutase
F0Q04_RS06245	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
F0Q04_RS06250	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
F0Q04_RS06255	ENOG4105DX0	Hemolysin A
F0Q04_RS06260	ENOG4105SYT	Methylenetetrahydrofolate reductase
F0Q04_RS06270	ENOG4105D6S	protein involved in catabolism of external DNA
F0Q04_RS06275	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F0Q04_RS06280	ENOG4108UJD	30S ribosomal protein S9
F0Q04_RS06285	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
F0Q04_RS06290	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0Q04_RS06295	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
F0Q04_RS06300	ENOG4105DR5	peptidase
F0Q04_RS06315	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS06325	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F0Q04_RS06330	ENOG4105BZU	Histidine kinase
F0Q04_RS06345	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
F0Q04_RS06360	ENOG4108KTG	Membrane protein, drug metabolite transporter
F0Q04_RS06365	ENOG4108ZT1	Transcriptional regulator
F0Q04_RS06385	ENOG4105BZU	Histidine kinase
F0Q04_RS06390	ENOG4105E0F	Histidine kinase
F0Q04_RS06395	ENOG4105CNM	Receptor
F0Q04_RS06415	ENOG4108WQI	RNA Polymerase
F0Q04_RS06475	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0Q04_RS06490	ENOG4105F2V	VRR-NUC domain-containing protein
F0Q04_RS06495	ENOG4105DVT	helicase
F0Q04_RS06500	ENOG4105CHB	tonB-dependent Receptor
F0Q04_RS06510	ENOG4105CFG	Acts as a chaperone (By similarity)
F0Q04_RS06525	ENOG4105CPC	Aldo Keto reductase
F0Q04_RS06530	ENOG4108JQ7	(ABC) transporter
F0Q04_RS06550	ENOG4105FBW	Monooxygenase
F0Q04_RS06555	ENOG4106R87	Extracellular solute-binding protein, family 5
F0Q04_RS06665	ENOG4105D7T	ABC transporter
F0Q04_RS06670	ENOG4108IFG	nitrite reductase, (NAD(P)H)
F0Q04_RS06680	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
F0Q04_RS06685	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F0Q04_RS06690	ENOG4108RH0	Crea protein
F0Q04_RS06705	ENOG4105BZ1	(ABC) transporter
F0Q04_RS06720	ENOG4105UGU	tonB-dependent Receptor
F0Q04_RS06730	ENOG4105C6F	GntR Family Transcriptional Regulator
F0Q04_RS06735	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
F0Q04_RS06745	ENOG4105D7Q	type ii secretion system
F0Q04_RS06750	ENOG4108K3A	Glutathione S-transferase
F0Q04_RS06760	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F0Q04_RS06765	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
F0Q04_RS06770	ENOG41060W2	glyoxylate carboligase
F0Q04_RS06775	ENOG4105CC0	LysR family Transcriptional regulator
F0Q04_RS06790	ENOG4105DEN	Luciferase family
F0Q04_RS06800	ENOG4107QHF	type ii secretion system protein e
F0Q04_RS06840	ENOG41069X0	general secretion pathway protein h
F0Q04_RS06845	ENOG4108VAU	general secretion pathway protein G
F0Q04_RS06860	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
F0Q04_RS06865	ENOG4105C7B	Threonine dehydratase
F0Q04_RS06890	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
F0Q04_RS06895	ENOG4108Z9W	Outer membrane porin
F0Q04_RS06910	ENOG4105CH2	amidohydrolase
F0Q04_RS06920	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS06925	ENOG4105C3U	ABC transporter
F0Q04_RS06930	ENOG4108JQ7	(ABC) transporter
F0Q04_RS06935	ENOG4105CGH	5'-nucleotidase
F0Q04_RS06945	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
F0Q04_RS06950	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F0Q04_RS06955	ENOG4107QP8	phosphohexose isomerase
F0Q04_RS06960	ENOG4107RP9	extracellular solute-binding protein, family 3
F0Q04_RS06965	ENOG4105E32	cytoplasmic protein
F0Q04_RS06975	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS06990	ENOG4105CNM	Receptor
F0Q04_RS06995	ENOG4108S3W	Anti-feci sigma factor, fecr
F0Q04_RS07005	ENOG4105BZ8	glutamate synthase
F0Q04_RS07010	ENOG4107SJI	Dehydrogenase
F0Q04_RS07015	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
F0Q04_RS07020	ENOG4105CD3	dihydroorotase
F0Q04_RS07025	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
F0Q04_RS07030	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F0Q04_RS07035	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F0Q04_RS07040	ENOG4108R86	Transcriptional regulator
F0Q04_RS07050	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0Q04_RS07055	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0Q04_RS07065	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0Q04_RS07070	ENOG4107TUY	Histidine kinase
F0Q04_RS07080	ENOG4105CRE	cytochrome C
F0Q04_RS07090	ENOG4105BZU	Histidine kinase
F0Q04_RS07095	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0Q04_RS07120	ENOG4105EM7	Selenocysteine-specific translation elongation factor
F0Q04_RS07125	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
F0Q04_RS07130	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
F0Q04_RS07135	ENOG4108MG3	formate dehydrogenase
F0Q04_RS07140	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
F0Q04_RS07150	ENOG4108QBX	(LipO)protein
F0Q04_RS07170	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F0Q04_RS07190	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
F0Q04_RS07195	ENOG4105EXG	Transcriptional regulator
F0Q04_RS07200	ENOG4105CF1	Alkylated DNA repair protein
F0Q04_RS07215	ENOG4105E39	Enoyl-CoA hydratase
F0Q04_RS07230	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
F0Q04_RS07240	ENOG4105C3G	gtp-binding protein
F0Q04_RS07250	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F0Q04_RS07260	ENOG4105W39	Membrane
F0Q04_RS07265	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F0Q04_RS07270	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
F0Q04_RS07275	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F0Q04_RS07280	ENOG4105W2Z	cytochrome C, class I
F0Q04_RS07290	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F0Q04_RS07300	ENOG4108UNF	response regulator
F0Q04_RS07305	ENOG4105M3Z	response regulator
F0Q04_RS07315	ENOG4105C8Q	Methyl-accepting chemotaxis
F0Q04_RS07320	ENOG4105CBS	Chea signal transduction histidine kinase
F0Q04_RS07325	ENOG4108UJU	UPF0301 protein
F0Q04_RS07330	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F0Q04_RS07340	ENOG4108UCS	ABC, transporter
F0Q04_RS07345	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS07365	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F0Q04_RS07385	ENOG4108RMU	ferritin dps family protein
F0Q04_RS07405	ENOG4105CMQ	Chloride channel
F0Q04_RS07420	ENOG4105R1U	AraC Family Transcriptional Regulator
F0Q04_RS07465	ENOG4105I8F	Histidine kinase
F0Q04_RS07510	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0Q04_RS07515	ENOG4106RE7	Cytochrome
F0Q04_RS07530	ENOG410829K	Lysine exporter protein (Lyse ygga)
F0Q04_RS07535	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
F0Q04_RS07545	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
F0Q04_RS07550	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
F0Q04_RS07560	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
F0Q04_RS07595	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
F0Q04_RS07605	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
F0Q04_RS07610	ENOG4108YZ9	Urea amidohydrolase subunit gamma
F0Q04_RS07620	ENOG4105KI2	Urea amidohydrolase subunit beta
F0Q04_RS07625	ENOG4105CQM	Urea amidohydrolase subunit alpha
F0Q04_RS07635	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
F0Q04_RS07640	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
F0Q04_RS07645	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
F0Q04_RS07680	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0Q04_RS07715	ENOG4106H78	methyltransferase
F0Q04_RS07720	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F0Q04_RS07750	ENOG4105WH1	Two component transcriptional regulator luxr family
F0Q04_RS07755	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0Q04_RS07760	ENOG4105D06	uba thif-type nad fad binding protein
F0Q04_RS07765	ENOG4105CN1	protease
F0Q04_RS07770	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F0Q04_RS07780	ENOG4105VW4	glutaredoxin 3
F0Q04_RS07785	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
F0Q04_RS07790	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F0Q04_RS07805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS07815	ENOG4105RQF	LysR family Transcriptional regulator
F0Q04_RS07840	ENOG4105EE5	Membrane protein terC
F0Q04_RS07875	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F0Q04_RS07890	ENOG4105D1F	ATP-binding protein
F0Q04_RS07910	ENOG410620I	Diguanylate cyclase
F0Q04_RS07915	ENOG4105CV6	ABC transporter, permease
F0Q04_RS07925	ENOG4108V0P	LemA family
F0Q04_RS07930	ENOG4105D0M	Protease HtpX homolog
F0Q04_RS07935	ENOG4105C98	muts2 protein
F0Q04_RS07940	ENOG4105W5Q	DNA repair protein (RadC
F0Q04_RS07950	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
F0Q04_RS07955	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F0Q04_RS07960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0Q04_RS07965	ENOG4105CYM	Glutathione S-transferase
F0Q04_RS07975	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F0Q04_RS07980	ENOG4105DUM	transcriptional regulator, lysR family
F0Q04_RS07990	ENOG4105C5H	ABC transporter
F0Q04_RS08000	ENOG4105JQN	Transcriptional regulator
F0Q04_RS08025	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
F0Q04_RS08030	ENOG4105C3F	Signal peptidase i
F0Q04_RS08040	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F0Q04_RS08045	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F0Q04_RS08050	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
F0Q04_RS08055	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
F0Q04_RS08060	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
F0Q04_RS08065	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
F0Q04_RS08090	ENOG4105CRK	lysyL-tRNA synthetase
F0Q04_RS08095	ENOG4108VIA	integral membrane protein
F0Q04_RS08100	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F0Q04_RS08105	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F0Q04_RS08110	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F0Q04_RS08115	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
F0Q04_RS08120	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F0Q04_RS08130	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F0Q04_RS08135	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F0Q04_RS08140	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F0Q04_RS08150	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F0Q04_RS08165	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F0Q04_RS08175	ENOG4105CFG	Acts as a chaperone (By similarity)
F0Q04_RS08180	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0Q04_RS08185	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
F0Q04_RS08195	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
F0Q04_RS08200	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
F0Q04_RS08205	ENOG4105CDU	Replicative dna helicase
F0Q04_RS08210	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS08215	ENOG4105C26	Dehydrogenase
F0Q04_RS08220	ENOG4105C7K	acetolactate synthase
F0Q04_RS08225	ENOG4108IAB	Phoh family
F0Q04_RS08230	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0Q04_RS08240	ENOG4105CHM	Aminotransferase
F0Q04_RS08245	ENOG4105D6E	homoserine dehydrogenase
F0Q04_RS08260	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
F0Q04_RS08265	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F0Q04_RS08285	ENOG4108ZAF	Molybdopterin
F0Q04_RS08290	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0Q04_RS08300	ENOG4107RGH	Aldehyde dehydrogenase
F0Q04_RS08310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F0Q04_RS08315	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
F0Q04_RS08320	ENOG4107RZC	phospholipase d
F0Q04_RS08330	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F0Q04_RS08365	ENOG4105VEJ	Heat shock protein
F0Q04_RS08370	ENOG4105DHQ	Histidine kinase
F0Q04_RS08435	ENOG4105DAN	ATP-dependent protease
F0Q04_RS08445	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
F0Q04_RS08450	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
F0Q04_RS08455	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
F0Q04_RS08460	ENOG4105HEI	LysR family (Transcriptional regulator
F0Q04_RS08470	ENOG4105FE1	phytoene synthase
F0Q04_RS08475	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0Q04_RS08480	ENOG4105DHQ	Histidine kinase
F0Q04_RS08490	ENOG4105C7K	acetolactate synthase
F0Q04_RS08495	ENOG4105C0H	protease
F0Q04_RS08505	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F0Q04_RS08510	ENOG4105BZS	acriflavin resistance protein
F0Q04_RS08520	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F0Q04_RS08525	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
F0Q04_RS08530	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F0Q04_RS08535	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F0Q04_RS08650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0Q04_RS08665	ENOG4105CHR	reductase
F0Q04_RS08670	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS08675	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS08710	ENOG4108VKG	metal-dependent hydrolase
F0Q04_RS08715	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
F0Q04_RS08725	ENOG4105CDY	transcriptional regulatory protein
F0Q04_RS08735	ENOG4108Z9W	Outer membrane porin
F0Q04_RS08745	ENOG4105BZU	Histidine kinase
F0Q04_RS08755	ENOG4108JQ9	ABC transporter
F0Q04_RS08760	ENOG4105UIB	(ABC) transporter
F0Q04_RS08785	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
F0Q04_RS08790	ENOG4105K59	histidine triad (HIT) protein
F0Q04_RS08795	ENOG4107QUY	Guanine deaminase
F0Q04_RS08800	ENOG4105DHP	deoxycytidine triphosphate deaminase
F0Q04_RS08805	ENOG4105CGZ	zinc metallopeptidase
F0Q04_RS08810	ENOG4105C1J	atp-dependent rna helicase
F0Q04_RS08815	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
F0Q04_RS08825	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
F0Q04_RS08830	ENOG4107QM5	aconitate hydratase
F0Q04_RS08835	ENOG4105BZU	Histidine kinase
F0Q04_RS08850	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
F0Q04_RS08855	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F0Q04_RS08865	ENOG4105D03	DNA-3-methyladenine glycosylase II
F0Q04_RS08870	ENOG4105C57	major facilitator superfamily
F0Q04_RS08875	ENOG4105JQN	Transcriptional regulator
F0Q04_RS08900	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
F0Q04_RS08905	ENOG4105C85	amino acid
F0Q04_RS08910	ENOG4105CYB	regulatoR
F0Q04_RS08920	ENOG4105E0Y	RtcB Protein
F0Q04_RS08930	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
F0Q04_RS08935	ENOG4105PI0	Ferredoxin
F0Q04_RS08940	ENOG4105GIJ	Glycine betaine
F0Q04_RS08945	ENOG4105GIJ	Glycine betaine
F0Q04_RS08950	ENOG4108HQS	Glycine betaine
F0Q04_RS08955	ENOG4108IJ7	Glycine betaine
F0Q04_RS08960	ENOG4108TEB	UPF0114 protein
F0Q04_RS08965	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0Q04_RS08975	ENOG4105W2Z	cytochrome C, class I
F0Q04_RS08985	ENOG4105C01	Dihydroxy-acid dehydratase
F0Q04_RS08990	ENOG4105DQ4	alcohol dehydrogenase
F0Q04_RS08995	ENOG4105KVH	Transcriptional regulator
F0Q04_RS09020	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F0Q04_RS09025	ENOG4105EB3	Histidine kinase
F0Q04_RS09050	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0Q04_RS09055	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0Q04_RS09060	ENOG4105C5Q	Transcriptional regulator
F0Q04_RS09065	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS09090	ENOG4108EC8	DNA internalization-related competence protein ComEC
F0Q04_RS09105	ENOG4105E0K	tonB-dependent siderophore receptor
F0Q04_RS09110	ENOG4108UQY	Iron-storage protein
F0Q04_RS09115	ENOG4105D3R	alkyl hydroperoxide reductase
F0Q04_RS09120	ENOG4108JU3	Alkyl hydroperoxide reductase
F0Q04_RS09125	ENOG4105DBV	ornithine carbamoyltransferase
F0Q04_RS09130	ENOG4105C8Y	Acetylornithine aminotransferase
F0Q04_RS09140	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
F0Q04_RS09145	ENOG4105CJR	Integral membrane protein (MviN
F0Q04_RS09150	ENOG41063JG	Transcriptional regulator
F0Q04_RS09155	ENOG4105CSR	polyphosphate kinase 2
F0Q04_RS09165	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F0Q04_RS09170	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F0Q04_RS09180	ENOG4105DJ0	Poly(A) Polymerase
F0Q04_RS09185	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0Q04_RS09195	ENOG4108EX3	reductase
F0Q04_RS09225	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F0Q04_RS09230	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F0Q04_RS09245	ENOG4105S7S	phosphonate abc transporter
F0Q04_RS09250	ENOG4105D5T	phosphonate abc transporter
F0Q04_RS09255	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
F0Q04_RS09260	ENOG4105CR8	Transcriptional regulator
F0Q04_RS09265	ENOG4108RYK	Nad-dependent epimerase dehydratase
F0Q04_RS09275	ENOG4108VDT	Glycosyl transferase family protein
F0Q04_RS09295	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS09300	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS09305	ENOG4108NVM	synthesis repressor PhaR
F0Q04_RS09320	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
F0Q04_RS09325	ENOG4105CSR	polyphosphate kinase 2
F0Q04_RS09330	ENOG4107QJQ	Mate efflux family protein
F0Q04_RS09340	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F0Q04_RS09350	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS09355	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F0Q04_RS09360	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
F0Q04_RS09365	ENOG4105K70	DNA-binding protein
F0Q04_RS09375	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
F0Q04_RS09395	ENOG4108S4H	thioesterase Superfamily protein
F0Q04_RS09405	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F0Q04_RS09410	ENOG4108I0Q	anthranilate phosphoribosyltransferase
F0Q04_RS09420	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F0Q04_RS09435	ENOG4105CVE	Lytic murein transglycosylase
F0Q04_RS09440	ENOG4105F8C	transglutaminase domain-containing protein
F0Q04_RS09450	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F0Q04_RS09460	ENOG4108M7F	enoyl-CoA hydratase isomerase
F0Q04_RS09465	ENOG4105EGS	Mechanosensitive ion channel
F0Q04_RS09470	ENOG4105BZJ	Electron transfer flavoprotein
F0Q04_RS09475	ENOG4105C10	Electron transfer flavoprotein
F0Q04_RS09480	ENOG4105CSU	acyl-Coa dehydrogenase
F0Q04_RS09510	ENOG4105NXH	GreA GreB family elongation factor
F0Q04_RS09520	ENOG4105DIJ	Phosphoethanolamine transferase
F0Q04_RS09525	ENOG4105BZN	citrate synthase
F0Q04_RS09530	ENOG41060IS	Flavinator of succinate dehydrogenase
F0Q04_RS09535	ENOG4105E33	succinate dehydrogenase
F0Q04_RS09545	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
F0Q04_RS09550	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
F0Q04_RS09555	ENOG4105FDP	GntR family transcriptional regulator
F0Q04_RS09560	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F0Q04_RS09565	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
F0Q04_RS09580	ENOG4107QIJ	Aconitate hydratase 2
F0Q04_RS09595	ENOG4105EX9	Membrane
F0Q04_RS09600	ENOG4108UWD	Iron-storage protein
F0Q04_RS09605	ENOG410756H	nucleotidyltransferase
F0Q04_RS09610	ENOG4107RSM	transcriptional regulator
F0Q04_RS09615	ENOG4105CSU	acyl-Coa dehydrogenase
F0Q04_RS09625	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS09650	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
F0Q04_RS09660	ENOG4105ECY	inositol monophosphatase
F0Q04_RS09670	ENOG4105D7W	serine acetyltransferase
F0Q04_RS09690	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F0Q04_RS09700	ENOG4105D82	Glutamate dehydrogenase
F0Q04_RS09705	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
F0Q04_RS09710	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
F0Q04_RS09715	ENOG4105CW7	secretion protein, HlyD family
F0Q04_RS09720	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0Q04_RS09725	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
F0Q04_RS09730	ENOG4105DQR	SNARE associated Golgi
F0Q04_RS09735	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F0Q04_RS09740	ENOG4105K8N	protein family UPF0079, ATPase
F0Q04_RS09745	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
F0Q04_RS09770	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F0Q04_RS09785	ENOG4105CWC	Acetylornithine deacetylase
F0Q04_RS09790	ENOG4105EAC	phosphoserine phosphatase
F0Q04_RS09795	ENOG4108JA2	transcriptioN-repair coupling factor
F0Q04_RS09800	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
F0Q04_RS09805	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
F0Q04_RS09815	ENOG4105E0F	Histidine kinase
F0Q04_RS09825	ENOG4105DTD	Dehydrogenase
F0Q04_RS09835	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F0Q04_RS09865	ENOG4105VDW	Csbd family
F0Q04_RS09870	ENOG4108302	MgtC SapB transporter
F0Q04_RS09875	ENOG4105QNF	Outer membrane lipoprotein
F0Q04_RS09920	ENOG4107QN1	sodium solute
F0Q04_RS09925	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0Q04_RS09935	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
F0Q04_RS09940	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0Q04_RS09945	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
F0Q04_RS09955	ENOG4105CX6	glutaminyL-tRNA synthetase
F0Q04_RS09965	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F0Q04_RS09975	ENOG4105D44	asparaginase
F0Q04_RS09980	ENOG4108JQ6	ABC transporter
F0Q04_RS09985	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS10000	ENOG4105WAP	TPR repeat-containing protein
F0Q04_RS10005	ENOG4105E9H	Lytic Murein transglycosylase
F0Q04_RS10010	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F0Q04_RS10015	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F0Q04_RS10020	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F0Q04_RS10025	ENOG4105IJJ	transcriptional regulator, crp fnr family
F0Q04_RS10035	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
F0Q04_RS10040	ENOG4105JQN	Transcriptional regulator
F0Q04_RS10075	ENOG4105CHH	sulfate transporter
F0Q04_RS10095	ENOG4105CSH	Transporter
F0Q04_RS10100	ENOG4108URH	decarboxylase
F0Q04_RS10105	ENOG41080IJ	Diacylglycerol kinase
F0Q04_RS10125	ENOG4105JVQ	RNA Polymerase
F0Q04_RS10130	ENOG4105C7K	acetolactate synthase
F0Q04_RS10135	ENOG4108ZP8	Acetolactate synthase small subunit
F0Q04_RS10140	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F0Q04_RS10145	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F0Q04_RS10150	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F0Q04_RS10155	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F0Q04_RS10160	ENOG41061WM	D-Alanyl-D-Alanine
F0Q04_RS10165	ENOG41069M3	Transcriptional regulator
F0Q04_RS10170	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
F0Q04_RS10175	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
F0Q04_RS10200	ENOG4105WD1	Membrane
F0Q04_RS10205	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F0Q04_RS10215	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F0Q04_RS10220	ENOG4108ETH	Formylglycinamide ribotide synthetase
F0Q04_RS10230	ENOG4108IXY	short-chain dehydrogenase reductase
F0Q04_RS10285	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
F0Q04_RS10290	ENOG4105RD5	
F0Q04_RS10295	ENOG4105DEG	Vwa containing coxe family protein
F0Q04_RS10305	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
F0Q04_RS10310	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
F0Q04_RS10315	ENOG4105CKW	Inner membrane protein yedI
F0Q04_RS10330	ENOG4105HMI	Membrane
F0Q04_RS10335	ENOG4105DUM	transcriptional regulator, lysR family
F0Q04_RS10340	ENOG4108UYB	regulatoR
F0Q04_RS10350	ENOG4108R6F	Surfeit locus 1 family protein
F0Q04_RS10355	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
F0Q04_RS10360	ENOG4105CCU	oxidase (Subunit III)
F0Q04_RS10365	ENOG4105BZ9	Cytochrome C oxidase, subunit I
F0Q04_RS10370	ENOG4105E2S	oxidase) subunit II
F0Q04_RS10375	ENOG4105CSH	Transporter
F0Q04_RS10380	ENOG4105CFP	Peptidase U32
F0Q04_RS10390	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
F0Q04_RS10400	ENOG41065RQ	ADP-ribosylation crystallin J1
F0Q04_RS10410	ENOG4108Z6B	deaminase
F0Q04_RS10415	ENOG4105C28	cystathionine
F0Q04_RS10420	ENOG4108UJV	acyl-CoA thioesterase i
F0Q04_RS10425	ENOG4108I0Y	(ABC) transporter
F0Q04_RS10440	ENOG4108YYH	Nadph-dependent fmn reductase
F0Q04_RS10455	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
F0Q04_RS10475	ENOG4105C8N	cysteinyl-tRNA synthetase
F0Q04_RS10485	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F0Q04_RS10490	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F0Q04_RS10495	ENOG4105CFH	Aspartokinase
F0Q04_RS10505	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
F0Q04_RS10510	ENOG4105CSH	Transporter
F0Q04_RS10515	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS10525	ENOG4105EQ2	LysR family Transcriptional regulator
F0Q04_RS10530	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
F0Q04_RS10535	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
F0Q04_RS10540	ENOG4105C7W	Xanthine dehydrogenase
F0Q04_RS10550	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F0Q04_RS10585	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
F0Q04_RS10590	ENOG4105EQ1	Transcriptional regulator
F0Q04_RS10605	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
F0Q04_RS10610	ENOG4105IW1	AmiS UreI transporter
F0Q04_RS10625	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
F0Q04_RS10630	ENOG4108S3N	antar domain-containing protein
F0Q04_RS10640	ENOG4107YNJ	LysR family Transcriptional regulator
F0Q04_RS10645	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0Q04_RS10655	ENOG4105CHR	reductase
F0Q04_RS10660	ENOG4105CMJ	mandelate racemase muconate lactonizing
F0Q04_RS10670	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
F0Q04_RS10680	ENOG4105CC9	acyl-Coa dehydrogenase
F0Q04_RS10700	ENOG4108Z9W	Outer membrane porin
F0Q04_RS10710	ENOG4105E39	Enoyl-CoA hydratase
F0Q04_RS10735	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
F0Q04_RS10745	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS10750	ENOG4108IV0	ABC, transporter
F0Q04_RS10755	ENOG4105C0Z	ABC transporter
F0Q04_RS10775	ENOG4107S2E	monooxygenase
F0Q04_RS10780	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0Q04_RS10785	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS10790	ENOG4105CSU	acyl-Coa dehydrogenase
F0Q04_RS10810	ENOG4105GIJ	Glycine betaine
F0Q04_RS10825	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0Q04_RS10830	ENOG4105CBS	Chea signal transduction histidine kinase
F0Q04_RS10840	ENOG4108KTQ	Methyltransferase
F0Q04_RS10850	ENOG4105C8Q	Methyl-accepting chemotaxis
F0Q04_RS10905	ENOG4105GAK	amidohydrolase 2
F0Q04_RS10910	ENOG4108JQ1	Dehydrogenase
F0Q04_RS10915	ENOG4105JSC	dimethylmenaquinone methyltransferase
F0Q04_RS10920	ENOG4105D4T	Citrate transporter
F0Q04_RS10935	ENOG4105ENE	Histidine kinase
F0Q04_RS10960	ENOG4108SF5	RNA Polymerase
F0Q04_RS10970	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
F0Q04_RS11015	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
F0Q04_RS11020	ENOG4108K4C	ec 3.1.3.12
F0Q04_RS11030	ENOG4105FDF	Could be involved in DNA repair (By similarity)
F0Q04_RS11080	ENOG4105F52	Transcriptional regulator
F0Q04_RS11095	ENOG4105BZN	citrate synthase
F0Q04_RS11100	ENOG4108I0Z	Aconitate hydratase
F0Q04_RS11105	ENOG4105C7F	AcnD-accessory protein PrpF
F0Q04_RS11125	ENOG4108XG2	Histidine kinase
F0Q04_RS11175	ENOG4105KHM	amidohydrolase 2
F0Q04_RS11185	ENOG4105GAK	amidohydrolase 2
F0Q04_RS11205	ENOG4105CPC	Aldo Keto reductase
F0Q04_RS11210	ENOG4105CHR	reductase
F0Q04_RS11220	ENOG4108I5G	Major Facilitator superfamily
F0Q04_RS11230	ENOG4105DND	Transcriptional regulator
F0Q04_RS11235	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
F0Q04_RS11240	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F0Q04_RS11245	ENOG4108K5P	(LipO)protein
F0Q04_RS11250	ENOG4105C34	Pseudouridine synthase
F0Q04_RS11255	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
F0Q04_RS11260	ENOG4105FE9	pseudouridine synthase
F0Q04_RS11265	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F0Q04_RS11270	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
F0Q04_RS11285	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
F0Q04_RS11290	ENOG4105CUT	histidyl-tRNA synthetase
F0Q04_RS11300	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0Q04_RS11305	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F0Q04_RS11310	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
F0Q04_RS11315	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F0Q04_RS11320	ENOG4107QJR	hflk protein
F0Q04_RS11325	ENOG4105EPW	hflc protein
F0Q04_RS11330	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
F0Q04_RS11335	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F0Q04_RS11405	ENOG4105CUX	Signal transduction histidine kinase
F0Q04_RS11410	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0Q04_RS11420	ENOG4105CK2	sodium dicarboxylate symporter
F0Q04_RS11425	ENOG4105CGK	Exodeoxyribonuclease III
F0Q04_RS11430	ENOG4105F4P	)-transporter
F0Q04_RS11440	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F0Q04_RS11445	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS11450	ENOG4107F3J	Amp-dependent synthetase and ligase
F0Q04_RS11455	ENOG4107ZYJ	bioY protein
F0Q04_RS11465	ENOG4108JJB	ABC transporter
F0Q04_RS11475	ENOG4105D01	(LipO)protein
F0Q04_RS11500	ENOG4107R16	Multicopper oxidase
F0Q04_RS11525	ENOG4105C8Y	Acetylornithine aminotransferase
F0Q04_RS11530	ENOG4105CUV	Homoserine Kinase
F0Q04_RS11535	ENOG4108WYP	Transcriptional regulator
F0Q04_RS11565	ENOG410904N	short-chain dehydrogenase reductase
F0Q04_RS11575	ENOG4105EUP	HipA domain protein
F0Q04_RS11615	ENOG4105JQN	Transcriptional regulator
F0Q04_RS11620	ENOG4105CC0	LysR family Transcriptional regulator
F0Q04_RS11625	ENOG4107S1E	Beta-lactamase
F0Q04_RS11660	ENOG4105HEI	LysR family (Transcriptional regulator
F0Q04_RS11690	ENOG41067B5	Histone deacetylase superfamily protein
F0Q04_RS11700	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
F0Q04_RS11705	ENOG4108JQ6	ABC transporter
F0Q04_RS11710	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS11715	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS11720	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS11725	ENOG4105MP9	class II Aldolase
F0Q04_RS11745	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS11755	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
F0Q04_RS11775	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F0Q04_RS11780	ENOG4105XYF	acetyltransferase
F0Q04_RS11795	ENOG4107S2N	Type III effector Hrp-dependent
F0Q04_RS11800	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F0Q04_RS11805	ENOG4105C0A	alcohol dehydrogenase
F0Q04_RS11810	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0Q04_RS11815	ENOG4105E98	transcriptional regulator DeoR family
F0Q04_RS11830	ENOG4108WUH	Transcriptional regulator, TetR family
F0Q04_RS11845	ENOG4105CZM	Major Facilitator
F0Q04_RS11880	ENOG4105CH2	amidohydrolase
F0Q04_RS11885	ENOG41080UQ	Transcriptional regulator
F0Q04_RS11890	ENOG410829K	Lysine exporter protein (Lyse ygga)
F0Q04_RS11915	ENOG4105E0F	Histidine kinase
F0Q04_RS11920	ENOG4108ZHJ	Organic hydroperoxide resistance protein
F0Q04_RS11965	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0Q04_RS11975	ENOG4105CD8	aminopeptidase N
F0Q04_RS11990	ENOG4105P8F	nudix hydrolase
F0Q04_RS12000	ENOG4105CPC	Aldo Keto reductase
F0Q04_RS12010	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
F0Q04_RS12020	ENOG4105E0K	tonB-dependent siderophore receptor
F0Q04_RS12025	ENOG4108VPT	UPF0234 protein
F0Q04_RS12030	ENOG4105D4A	Cell wall formation (By similarity)
F0Q04_RS12040	ENOG4108JEH	abc transporter atp-binding protein
F0Q04_RS12050	ENOG4105DSP	amino acid AbC transporter
F0Q04_RS12055	ENOG4105E89	ABC transporter
F0Q04_RS12075	ENOG4107RNH	Outer membrane receptor FepA
F0Q04_RS12095	ENOG4108UKI	Enoyl-CoA hydratase
F0Q04_RS12115	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
F0Q04_RS12125	ENOG4105SB3	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
F0Q04_RS12135	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
F0Q04_RS12140	ENOG4105HDK	L-asparaginase
F0Q04_RS12145	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F0Q04_RS12150	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F0Q04_RS12160	ENOG4105W49	UPF0434 protein
F0Q04_RS12165	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F0Q04_RS12180	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F0Q04_RS12185	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0Q04_RS12190	ENOG4105CNM	Receptor
F0Q04_RS12195	ENOG4108SF5	RNA Polymerase
F0Q04_RS12200	ENOG4108S3W	Anti-feci sigma factor, fecr
F0Q04_RS12210	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
F0Q04_RS12215	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
F0Q04_RS12220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0Q04_RS12225	ENOG4105BZU	Histidine kinase
F0Q04_RS12260	ENOG4105BZ1	(ABC) transporter
F0Q04_RS12265	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
F0Q04_RS12270	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F0Q04_RS12280	ENOG4105CUZ	uba thif-type nad fad binding protein
F0Q04_RS12350	ENOG4105K70	DNA-binding protein
F0Q04_RS12415	ENOG4105CDU	Replicative dna helicase
F0Q04_RS12625	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F0Q04_RS12630	ENOG4105KT5	UmuD protein
F0Q04_RS12670	ENOG4105CP9	extracellular ligand-binding receptor
F0Q04_RS12675	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS12680	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
F0Q04_RS12685	ENOG4105C0Z	ABC transporter
F0Q04_RS12690	ENOG4108IV0	ABC, transporter
F0Q04_RS12695	ENOG4105EWT	decarboxylase family
F0Q04_RS12700	ENOG4107Z6W	Protein CrcB homolog
F0Q04_RS12715	ENOG4105W4C	monovalent cation H antiporter subunit F
F0Q04_RS12725	ENOG4107R4Z	monovalent cation h antiporter subunit d
F0Q04_RS12730	ENOG4108ZE9	Monovalent cation H antiporter subunit C
F0Q04_RS12735	ENOG4105D65	subunit l
F0Q04_RS12740	ENOG4105CFV	Tetratricopeptide repeat protein
F0Q04_RS12755	ENOG4107QMP	dna polymerase iii subunits gamma and tau
F0Q04_RS12760	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
F0Q04_RS12765	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
F0Q04_RS12770	ENOG4105CSH	Transporter
F0Q04_RS12780	ENOG4105ED9	Protein of unknown function (DUF455)
F0Q04_RS12785	ENOG4108Z0R	Transferase
F0Q04_RS12790	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
F0Q04_RS12800	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F0Q04_RS12805	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
F0Q04_RS12820	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F0Q04_RS12825	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
F0Q04_RS12830	ENOG4105DG4	malate L-lactate dehydrogenase
F0Q04_RS12850	ENOG4105EN6	Membrane
F0Q04_RS12860	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
F0Q04_RS12865	ENOG4108I5D	sulfate abc transporter
F0Q04_RS12870	ENOG4105ECW	sulfate abc transporter
F0Q04_RS12875	ENOG4108IJ6	ABC transporter
F0Q04_RS12880	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
F0Q04_RS12925	ENOG4105C1J	atp-dependent rna helicase
F0Q04_RS12930	ENOG4105C5H	ABC transporter
F0Q04_RS12945	ENOG4105DSY	exodeoxyribonuclease V, gamma
F0Q04_RS12950	ENOG4107QKA	exodeoxyribonuclease V beta
F0Q04_RS12955	ENOG4107QYX	exodeoxyribonuclease v alpha
F0Q04_RS12970	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F0Q04_RS12975	ENOG4108ZJF	Glcg protein
F0Q04_RS12995	ENOG4105C72	UPF0176 protein
F0Q04_RS13005	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS13015	ENOG4108EKC	n-acetylglutamate synthase
F0Q04_RS13025	ENOG4108MEJ	flavin reductase domain protein
F0Q04_RS13035	ENOG4105CQ7	ATP-dependent helicase
F0Q04_RS13040	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
F0Q04_RS13045	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
F0Q04_RS13065	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS13080	ENOG4105C5H	ABC transporter
F0Q04_RS13090	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
F0Q04_RS13095	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F0Q04_RS13100	ENOG4105CZX	twitching motility protein
F0Q04_RS13105	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
F0Q04_RS13115	ENOG4108R3D	Electron transport complex
F0Q04_RS13130	ENOG4105F4G	Membrane
F0Q04_RS13135	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
F0Q04_RS13140	ENOG4105C7S	Dehydrogenase
F0Q04_RS13150	ENOG4107QN2	dihydrolipoyl dehydrogenase
F0Q04_RS13155	ENOG4105D6Z	AFG1 family ATPase
F0Q04_RS13165	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F0Q04_RS13170	ENOG4105CRW	Short chain fatty acid transporter
F0Q04_RS13185	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F0Q04_RS13200	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0Q04_RS13205	ENOG4105EB3	Histidine kinase
F0Q04_RS13210	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
F0Q04_RS13225	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F0Q04_RS13235	ENOG41081QV	Universal stress protein
F0Q04_RS13250	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0Q04_RS13325	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F0Q04_RS13340	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F0Q04_RS13345	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F0Q04_RS13370	ENOG4105C5I	Dehydrogenase
F0Q04_RS13390	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
F0Q04_RS13400	ENOG4106PMH	Extracellular solute-binding protein family 3
F0Q04_RS13405	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS13415	ENOG4105D7A	ATP-binding protein
F0Q04_RS13420	ENOG4105CDY	transcriptional regulatory protein
F0Q04_RS13425	ENOG4105C12	Phosphoribosylglycinamide synthetase
F0Q04_RS13430	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F0Q04_RS13435	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
F0Q04_RS13440	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F0Q04_RS13445	ENOG4108Z03	MAF-like protein
F0Q04_RS13450	ENOG4105C03	ribonuclease
F0Q04_RS13455	ENOG4105CHM	Aminotransferase
F0Q04_RS13460	ENOG4107R11	Transcriptional regulator
F0Q04_RS13470	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F0Q04_RS13475	ENOG4105BZS	acriflavin resistance protein
F0Q04_RS13480	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F0Q04_RS13485	ENOG4105CAY	ferredoxin--nadp reductase
F0Q04_RS13505	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
F0Q04_RS13515	ENOG4108M0I	Transcriptional regulator
F0Q04_RS13520	ENOG4105DHU	Bile acid
F0Q04_RS13535	ENOG4105BZM	domain protein
F0Q04_RS13540	ENOG4105DSF	transport protein
F0Q04_RS13545	ENOG4105HEI	LysR family (Transcriptional regulator
F0Q04_RS13550	ENOG4105F27	Major Facilitator
F0Q04_RS13555	ENOG4105CV8	reductase
F0Q04_RS13560	ENOG4105RQF	LysR family Transcriptional regulator
F0Q04_RS13590	ENOG4105E89	ABC transporter
F0Q04_RS13595	ENOG4105CDA	abc transporter atp-binding protein
F0Q04_RS13600	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS13605	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS13610	ENOG4105C5I	Dehydrogenase
F0Q04_RS13665	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0Q04_RS13670	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
F0Q04_RS13680	ENOG4107RCV	ABC transporter, permease
F0Q04_RS13690	ENOG4105C4Y	ABC transporter
F0Q04_RS13745	ENOG4105NZG	Ferredoxin
F0Q04_RS13750	ENOG4105E0A	ABC, transporter
F0Q04_RS13755	ENOG4105EHG	Permease protein
F0Q04_RS13770	ENOG4105DQS	Transcriptional regulator
F0Q04_RS13775	ENOG4105CSH	Transporter
F0Q04_RS13790	ENOG4105XPH	Ferredoxin
F0Q04_RS13795	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0Q04_RS13800	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0Q04_RS13820	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
F0Q04_RS13835	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0Q04_RS13840	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
F0Q04_RS13850	ENOG4105C09	Bile acid
F0Q04_RS13865	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
F0Q04_RS13880	ENOG4107QN2	dihydrolipoyl dehydrogenase
F0Q04_RS13885	ENOG4107QSN	dihydrolipoamide acetyltransferase
F0Q04_RS13890	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
F0Q04_RS13895	ENOG4105BZU	Histidine kinase
F0Q04_RS13900	ENOG4108ZXC	Two component transcriptional regulator, luxr family
F0Q04_RS13905	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
F0Q04_RS13910	ENOG4105DGW	oligopeptidase A
F0Q04_RS13920	ENOG4105E66	phosphoriboisomerase A
F0Q04_RS13925	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
F0Q04_RS13930	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F0Q04_RS13945	ENOG4105BZU	Histidine kinase
F0Q04_RS13955	ENOG4105CCT	upf0313 protein
F0Q04_RS13965	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
F0Q04_RS13980	ENOG4105CHR	reductase
F0Q04_RS13985	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS13990	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
F0Q04_RS14000	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0Q04_RS14005	ENOG41082BV	acetyltransferase
F0Q04_RS14035	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
F0Q04_RS14055	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F0Q04_RS14065	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
F0Q04_RS14070	ENOG4105CNG	UPF0061 protein
F0Q04_RS14075	ENOG4105E0X	reductase
F0Q04_RS14080	ENOG4107835	probably involved in intracellular septation (By similarity)
F0Q04_RS14090	ENOG4107TF3	peptidylprolyl cis-trans isomerase
F0Q04_RS14095	ENOG4108UYE	Lactoylglutathione lyase
F0Q04_RS14100	ENOG4105BZU	Histidine kinase
F0Q04_RS14110	ENOG4108UHU	Aldolase
F0Q04_RS14115	ENOG4105C01	Dihydroxy-acid dehydratase
F0Q04_RS14120	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
F0Q04_RS14145	ENOG4107QX3	carboxylase
F0Q04_RS14150	ENOG4105DJT	lAO AO transport system ATPase
F0Q04_RS14170	ENOG4105DRR	Transcriptional regulator, GntR family
F0Q04_RS14175	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
F0Q04_RS14180	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F0Q04_RS14185	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F0Q04_RS14190	ENOG4105K63	Thioredoxin
F0Q04_RS14200	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
F0Q04_RS14210	ENOG4105CHH	sulfate transporter
F0Q04_RS14215	ENOG4105C72	UPF0176 protein
F0Q04_RS14230	ENOG4105CWB	LysR family transcriptional Regulator
F0Q04_RS14235	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F0Q04_RS14240	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
F0Q04_RS14260	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F0Q04_RS14270	ENOG4105CHR	reductase
F0Q04_RS14275	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS14280	ENOG4105D3G	Pseudouridine synthase
F0Q04_RS14285	ENOG4105CHR	reductase
F0Q04_RS14290	ENOG410904N	short-chain dehydrogenase reductase
F0Q04_RS14295	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS14305	ENOG4108K0D	peptidase, M48
F0Q04_RS14310	ENOG4107R11	Transcriptional regulator
F0Q04_RS14315	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
F0Q04_RS14320	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
F0Q04_RS14330	ENOG4105DZC	cytosine deaminase
F0Q04_RS14340	ENOG41083U2	ABC transporter, permease
F0Q04_RS14345	ENOG4108JQ9	ABC transporter
F0Q04_RS14350	ENOG4107TFB	basic membrane
F0Q04_RS14370	ENOG4105D5U	fad dependent oxidoreductase
F0Q04_RS14375	ENOG4105F0N	pyrophosphate phospho-hydrolase
F0Q04_RS14390	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS14400	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS14410	ENOG4105C85	amino acid
F0Q04_RS14420	ENOG4105C26	Dehydrogenase
F0Q04_RS14430	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS14440	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F0Q04_RS14450	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F0Q04_RS14465	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
F0Q04_RS14475	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
F0Q04_RS14480	ENOG4108Z4U	Ferredoxin
F0Q04_RS14485	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
F0Q04_RS14495	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0Q04_RS14510	ENOG4105CJB	Exodeoxyribonuclease I
F0Q04_RS14515	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F0Q04_RS14525	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0Q04_RS14530	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
F0Q04_RS14535	ENOG4105C0B	DNA polymerase III (alpha subunit)
F0Q04_RS14540	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0Q04_RS14545	ENOG4105DVT	helicase
F0Q04_RS14555	ENOG4105D01	(LipO)protein
F0Q04_RS14565	ENOG4108UMI	ABC transporter, permease
F0Q04_RS14570	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS14585	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F0Q04_RS14595	ENOG4108K5H	permease YjgP YjgQ family protein
F0Q04_RS14600	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F0Q04_RS14605	ENOG4105DJ4	phosphatidylserine decarboxylase
F0Q04_RS14610	ENOG4105D3G	Pseudouridine synthase
F0Q04_RS14620	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F0Q04_RS14625	ENOG4107QKV	phosphomannomutase
F0Q04_RS14640	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F0Q04_RS14645	ENOG4105YA8	Transcriptional regulator
F0Q04_RS14660	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F0Q04_RS14670	ENOG4105DFG	type I secretion outer membrane protein
F0Q04_RS14695	ENOG4107RZZ	dna polymerase iii epsilon subunit
F0Q04_RS14700	ENOG4108ZIT	Ferredoxin, 2FE-2S
F0Q04_RS14705	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
F0Q04_RS14710	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
F0Q04_RS14720	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
F0Q04_RS14725	ENOG4105C3J	Cysteine desulfurase
F0Q04_RS14730	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
F0Q04_RS14740	ENOG4105CGF	Aromatic amino acid aminotransferase
F0Q04_RS14760	ENOG4105K4H	Nlp p60 protein
F0Q04_RS14785	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
F0Q04_RS14790	ENOG4108Z7F	N-acetyltransferase
F0Q04_RS14815	ENOG4108ZXC	Two component transcriptional regulator, luxr family
F0Q04_RS14820	ENOG4105CEP	NADH dehydrogenase
F0Q04_RS14830	ENOG4105EW9	transcriptional regulator AsnC family
F0Q04_RS14835	ENOG4107QWB	Ornithine cyclodeaminase
F0Q04_RS14840	ENOG41066UZ	arginase EC 3.5.3.1
F0Q04_RS14845	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
F0Q04_RS14850	ENOG4105DND	Transcriptional regulator
F0Q04_RS14865	ENOG4105C26	Dehydrogenase
F0Q04_RS14875	ENOG4105C26	Dehydrogenase
F0Q04_RS14880	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F0Q04_RS14890	ENOG4108Z40	Transcriptional regulator
F0Q04_RS14900	ENOG4108R4R	Iron-regulated virulence regulatory protein
F0Q04_RS14905	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
F0Q04_RS14930	ENOG410650H	(LipO)protein
F0Q04_RS14940	ENOG4105EKT	)-iron permease
F0Q04_RS14945	ENOG4108ZXC	Two component transcriptional regulator, luxr family
F0Q04_RS14950	ENOG4105BZU	Histidine kinase
F0Q04_RS14965	ENOG4107QUT	magnesium and cobalt transport protein CorA
F0Q04_RS14975	ENOG4107QUT	magnesium and cobalt transport protein CorA
F0Q04_RS14990	ENOG4105E9K	Isocitrate dehydrogenase
F0Q04_RS14995	ENOG4108YZN	class I peptide chain release factor
F0Q04_RS15005	ENOG4105E0F	Histidine kinase
F0Q04_RS15015	ENOG4105D05	Receptor
F0Q04_RS15020	ENOG4105D05	Receptor
F0Q04_RS15045	ENOG4105CHR	reductase
F0Q04_RS15055	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
F0Q04_RS15070	ENOG4105KXX	peptidase s58 dmpa
F0Q04_RS15115	ENOG4108JJ9	ABC, transporter
F0Q04_RS15120	ENOG4108JJ8	(ABC) transporter
F0Q04_RS15125	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F0Q04_RS15130	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F0Q04_RS15165	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F0Q04_RS15175	ENOG4108JJA	ABC, transporter
F0Q04_RS15255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0Q04_RS15265	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
F0Q04_RS15270	ENOG4105YVS	arsR family transcriptional regulator
F0Q04_RS15275	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F0Q04_RS15280	ENOG4105CBN	LysR family transcriptional regulator
F0Q04_RS15285	ENOG4105CHR	reductase
F0Q04_RS15290	ENOG4105CXK	mandelate racemase muconate lactonizing
F0Q04_RS15295	ENOG4105CPQ	Dehydrogenase
F0Q04_RS15300	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS15305	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS15310	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
F0Q04_RS15315	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS15325	ENOG4105CHR	reductase
F0Q04_RS15330	ENOG4107EJG	GntR family transcriptional regulator
F0Q04_RS15345	ENOG4105DFA	alanine racemase domain protein
F0Q04_RS15650	ENOG4105CFI	type iii restriction protein res subunit
F0Q04_RS15675	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0Q04_RS15695	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F0Q04_RS15705	ENOG4105VDB	UPF0125 protein
F0Q04_RS15710	ENOG4108Z1B	Cyclase dehydrase
F0Q04_RS15715	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F0Q04_RS15735	ENOG4105E39	Enoyl-CoA hydratase
F0Q04_RS15740	ENOG4105D2B	acyl-CoA dehydrogenase
F0Q04_RS15745	ENOG4105D2B	acyl-CoA dehydrogenase
F0Q04_RS15760	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS15765	ENOG4107RSM	transcriptional regulator
F0Q04_RS15770	ENOG4105CI3	gtp-binding protein typa
F0Q04_RS15775	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
F0Q04_RS15780	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F0Q04_RS15785	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
F0Q04_RS15790	ENOG4105CHV	Transcription elongation factor NusA
F0Q04_RS15795	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
F0Q04_RS15815	ENOG4105QNF	Outer membrane lipoprotein
F0Q04_RS15820	ENOG4108IV0	ABC, transporter
F0Q04_RS15825	ENOG4105C0Z	ABC transporter
F0Q04_RS15830	ENOG4108JQ5	ABC transporter
F0Q04_RS15835	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
F0Q04_RS15845	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
F0Q04_RS15850	ENOG4105E43	Extracellular solute-binding protein, family 5
F0Q04_RS15855	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
F0Q04_RS15870	ENOG4105F8V	Hydrolase, tatD family
F0Q04_RS15880	ENOG4107QRG	dna polymerase iii
F0Q04_RS15885	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
F0Q04_RS15905	ENOG4105C5I	Dehydrogenase
F0Q04_RS15915	ENOG4107RH7	Nicotinate phosphoribosyltransferase
F0Q04_RS15925	ENOG4108WFY	phasin family
F0Q04_RS15995	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F0Q04_RS16000	ENOG4105C28	cystathionine
F0Q04_RS16005	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F0Q04_RS16020	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F0Q04_RS16025	ENOG4105KUZ	arsenate reductase
F0Q04_RS16035	ENOG4105NBK	UPF0345 protein
F0Q04_RS16040	ENOG4105CDH	Citrulline--aspartate ligase
F0Q04_RS16050	ENOG4108I9X	Isocitrate lyase
F0Q04_RS16100	ENOG4105EW9	transcriptional regulator AsnC family
F0Q04_RS16115	ENOG4108S0S	Nucleotidyl transferase
F0Q04_RS16120	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS16130	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS16135	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F0Q04_RS16140	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F0Q04_RS16145	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0Q04_RS16155	ENOG4105BZU	Histidine kinase
F0Q04_RS16160	ENOG4105HHA	aminodeoxychorismate lyase
F0Q04_RS16165	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
F0Q04_RS16190	ENOG4108IQE	Amp-dependent synthetase and ligase
F0Q04_RS16210	ENOG4105DZG	Dehydrogenase
F0Q04_RS16220	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
F0Q04_RS16235	ENOG4105C7J	ABC transporter, permease
F0Q04_RS16260	ENOG410642W	LysR family Transcriptional regulator
F0Q04_RS16265	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F0Q04_RS16270	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
F0Q04_RS16275	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
F0Q04_RS16285	ENOG4105F87	Dehydratase
F0Q04_RS16295	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
F0Q04_RS16310	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F0Q04_RS16315	ENOG4105NRA	50s ribosomal protein l31 type b
F0Q04_RS16325	ENOG4107QI1	Mate efflux family protein
F0Q04_RS16330	ENOG4105BZU	Histidine kinase
F0Q04_RS16335	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0Q04_RS16340	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
F0Q04_RS16345	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS16350	ENOG4105E2Z	phosphate ABC transporter (Permease
F0Q04_RS16355	ENOG4105C8U	phosphate abc transporter
F0Q04_RS16360	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
F0Q04_RS16365	ENOG4105C9X	ppx gppa phosphatase
F0Q04_RS16370	ENOG4105C5I	Dehydrogenase
F0Q04_RS16380	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
F0Q04_RS16385	ENOG4105EEI	dihydropteroate synthase
F0Q04_RS16390	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0Q04_RS16395	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
F0Q04_RS16400	ENOG4105HBR	Rna-binding protein
F0Q04_RS16420	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F0Q04_RS16425	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F0Q04_RS16440	ENOG4108RWN	rrna methyltransferase
F0Q04_RS16445	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F0Q04_RS16450	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0Q04_RS16455	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0Q04_RS16460	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F0Q04_RS16465	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0Q04_RS16475	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0Q04_RS16480	ENOG4105DZP	Membrane-associated zinc metalloprotease
F0Q04_RS16485	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
F0Q04_RS16490	ENOG4105KNE	Phosphatidate cytidylyltransferase
F0Q04_RS16500	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
F0Q04_RS16505	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
F0Q04_RS16510	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F0Q04_RS16515	ENOG4105CE9	30S ribosomal protein S2
F0Q04_RS16520	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0Q04_RS16525	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F0Q04_RS16530	ENOG4105CHR	reductase
F0Q04_RS16535	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F0Q04_RS16570	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
F0Q04_RS16575	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F0Q04_RS16580	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
F0Q04_RS16585	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
F0Q04_RS16590	ENOG410846T	CoA-transferase family III
F0Q04_RS16595	ENOG4105BZN	citrate synthase
F0Q04_RS16610	ENOG4108R6G	acetyltransferase
F0Q04_RS16625	ENOG4107S2Z	UPF0761 membrane protein
F0Q04_RS16635	ENOG4105CQB	FAD linked oxidase domain protein
F0Q04_RS16685	ENOG4105CHR	reductase
F0Q04_RS16690	ENOG4108RK3	acyl-Coa dehydrogenase
F0Q04_RS16695	ENOG4105CC9	acyl-Coa dehydrogenase
F0Q04_RS16705	ENOG4105E39	Enoyl-CoA hydratase
F0Q04_RS16715	ENOG4105EJC	lysr family transcriptional regulator
F0Q04_RS16725	ENOG4105CNW	domain protein
F0Q04_RS16730	ENOG41090TK	Short-chain dehydrogenase reductase Sdr
F0Q04_RS16750	ENOG4105RQF	LysR family Transcriptional regulator
F0Q04_RS16760	ENOG4107SQD	Transcriptional regulator, GntR family
F0Q04_RS16770	ENOG4107SCK	Monooxygenase
F0Q04_RS16780	ENOG4105CAU	Arsenical resistance protein, ArsH
F0Q04_RS16785	ENOG4105D6J	arsenicaL-resistance protein
F0Q04_RS16790	ENOG4108UXE	Protein tyrosine phosphatase
F0Q04_RS16800	ENOG4108UVJ	appr-1-p processing domain protein
F0Q04_RS16805	ENOG4107QRP	cobalamin biosynthesis protein CobW
F0Q04_RS16810	ENOG4105CTK	cobaltochelatase, cobn subunit
F0Q04_RS16825	ENOG4105GAV	receptor
F0Q04_RS16860	ENOG4108SF5	RNA Polymerase
F0Q04_RS16865	ENOG4108S3W	Anti-feci sigma factor, fecr
F0Q04_RS16870	ENOG4105CNM	Receptor
F0Q04_RS16875	ENOG4105BZU	Histidine kinase
F0Q04_RS16880	ENOG4105T2N	Domain of unknown function (DUF2382)
F0Q04_RS16885	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
F0Q04_RS16930	ENOG4105BZU	Histidine kinase
F0Q04_RS16935	ENOG4105BZU	Histidine kinase
F0Q04_RS16940	ENOG4105BZU	Histidine kinase
F0Q04_RS16950	ENOG4105WH1	Two component transcriptional regulator luxr family
F0Q04_RS16990	ENOG4105EU0	Major facilitator Superfamily
F0Q04_RS17020	ENOG4105ETE	Transcriptional regulator (LacI family
F0Q04_RS17030	ENOG4105EQX	glucarate dehydratase
F0Q04_RS17035	ENOG41069M3	Transcriptional regulator
F0Q04_RS17045	ENOG4105GAK	amidohydrolase 2
F0Q04_RS17055	ENOG4105JSC	dimethylmenaquinone methyltransferase
F0Q04_RS17060	ENOG4108JQ1	Dehydrogenase
F0Q04_RS17065	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
F0Q04_RS17085	ENOG4105NIV	Esterase
F0Q04_RS17120	ENOG4105JQN	Transcriptional regulator
F0Q04_RS17125	ENOG4105HEI	LysR family (Transcriptional regulator
F0Q04_RS17130	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
F0Q04_RS17135	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS17145	ENOG4105D2X	ABC transporter substrate-binding protein
F0Q04_RS17160	ENOG4105DZ2	Transcriptional regulator
F0Q04_RS17195	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS17200	ENOG4105DQ4	alcohol dehydrogenase
F0Q04_RS17220	ENOG4108S3W	Anti-feci sigma factor, fecr
F0Q04_RS17225	ENOG4108SF5	RNA Polymerase
F0Q04_RS17245	ENOG4108JIK	carboxylase
F0Q04_RS17250	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS17255	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS17340	ENOG4105C0D	helicase
F0Q04_RS17370	ENOG4108NF7	phage-type endonuclease
F0Q04_RS17395	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F0Q04_RS17430	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F0Q04_RS17625	ENOG4108TFU	terminase (Small subunit)
F0Q04_RS17665	ENOG4105NY2	NinB protein
F0Q04_RS17810	ENOG4108PNI	recT protein
F0Q04_RS17875	ENOG4107R08	Integrase
F0Q04_RS17885	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F0Q04_RS17890	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F0Q04_RS17895	ENOG4105UYK	outer membrane protein a
F0Q04_RS17900	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0Q04_RS17905	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F0Q04_RS17920	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
F0Q04_RS17925	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F0Q04_RS17930	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F0Q04_RS17935	ENOG4105DGI	Alkaline phosphatase
F0Q04_RS17955	ENOG4105E4C	Lytic transglycosylase catalytic
F0Q04_RS17975	ENOG41080HT	Transcriptional regulator, arsr family
F0Q04_RS17990	ENOG4105DR9	pseudouridine synthase
F0Q04_RS18010	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0Q04_RS18020	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
F0Q04_RS18040	ENOG4105D9M	gamma-glutamylcysteine synthetase
F0Q04_RS18045	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
F0Q04_RS18055	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F0Q04_RS18060	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F0Q04_RS18065	ENOG4107YIM	Involved in the transcription termination process (By similarity)
F0Q04_RS18070	ENOG4105CHM	Aminotransferase
F0Q04_RS18075	ENOG4107YD3	Thioesterase
F0Q04_RS18080	ENOG4105E02	MotA TolQ exbB proton channel
F0Q04_RS18085	ENOG4105M15	transport protein ExbD
F0Q04_RS18095	ENOG4105CHR	reductase
F0Q04_RS18105	ENOG4106517	Short-chain dehydrogenase reductase Sdr
F0Q04_RS18115	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
F0Q04_RS18120	ENOG4105BZ1	(ABC) transporter
F0Q04_RS18130	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
F0Q04_RS18150	ENOG4105F4R	Transcriptional regulator mode
F0Q04_RS18155	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
F0Q04_RS18160	ENOG4105E0C	molybdate abc transporter
F0Q04_RS18165	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS18180	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS18185	ENOG4105CH5	extracellular solute-binding protein, family 7
F0Q04_RS18190	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F0Q04_RS18195	ENOG4105CTB	Polyprenyl synthetase
F0Q04_RS18200	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F0Q04_RS18215	ENOG4105KHC	sulfurtransferase
F0Q04_RS18225	ENOG410814C	multidrug resistance protein
F0Q04_RS18230	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
F0Q04_RS18235	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
F0Q04_RS18265	ENOG4108YYC	ycei family
F0Q04_RS18275	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F0Q04_RS18280	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
F0Q04_RS18290	ENOG4105C6T	cysteine synthase
F0Q04_RS18390	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F0Q04_RS18395	ENOG4105BZS	acriflavin resistance protein
F0Q04_RS18400	ENOG4105BZS	acriflavin resistance protein
F0Q04_RS18415	ENOG4105DWF	phosphomethylpyrimidine kinase
F0Q04_RS18425	ENOG4105CBX	hi0933 family
F0Q04_RS18430	ENOG4105VCC	30S ribosomal protein S21
F0Q04_RS18450	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS18470	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F0Q04_RS18495	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS18500	ENOG4106NZI	LysR family Transcriptional regulator
F0Q04_RS18510	ENOG4108R6K	riboflavin synthase, subunit alpha
F0Q04_RS18515	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
F0Q04_RS18520	ENOG4105N42	UPF0307 protein
F0Q04_RS18525	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
F0Q04_RS18530	ENOG4105C2C	drug resistance transporter, Bcr CflA
F0Q04_RS18540	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
F0Q04_RS18560	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
F0Q04_RS18575	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS18585	ENOG4108IV0	ABC, transporter
F0Q04_RS18590	ENOG4105C0Z	ABC transporter
F0Q04_RS18605	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0Q04_RS18610	ENOG4105C8S	subunit m
F0Q04_RS18620	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0Q04_RS18625	ENOG4105DF2	NADH dehydrogenase subunit j
F0Q04_RS18630	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0Q04_RS18635	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
F0Q04_RS18640	ENOG4108IEH	NADH dehydrogenase subunit g
F0Q04_RS18645	ENOG4107QIZ	NADH dehydrogenase
F0Q04_RS18655	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0Q04_RS18660	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F0Q04_RS18665	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F0Q04_RS18670	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F0Q04_RS18680	ENOG4107EJC	Preprotein translocase subunit SecG
F0Q04_RS18685	ENOG4105CP7	Triose-phosphate isomerase
F0Q04_RS18695	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
F0Q04_RS18700	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F0Q04_RS18720	ENOG41079KZ	Major Facilitator Superfamily
F0Q04_RS18730	ENOG4105ETT	transcriptional Regulator, LysR family
F0Q04_RS18740	ENOG4105YK5	50S ribosomal protein L36
F0Q04_RS18745	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
F0Q04_RS18785	ENOG4105C0B	DNA polymerase III (alpha subunit)
F0Q04_RS18795	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0Q04_RS18800	ENOG4105CR8	Transcriptional regulator
F0Q04_RS18810	ENOG4105CNM	Receptor
F0Q04_RS18840	ENOG4105EJC	lysr family transcriptional regulator
F0Q04_RS18855	ENOG4105EQ2	LysR family Transcriptional regulator
F0Q04_RS18875	ENOG4105EJC	lysr family transcriptional regulator
F0Q04_RS18880	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F0Q04_RS18885	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F0Q04_RS18890	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
F0Q04_RS18915	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0Q04_RS18920	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
F0Q04_RS18950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0Q04_RS18965	ENOG4105CQ2	DNA polymerase
F0Q04_RS18980	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F0Q04_RS18985	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
F0Q04_RS18990	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F0Q04_RS18995	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
F0Q04_RS19000	ENOG4105VJV	50s ribosomal protein L35
F0Q04_RS19005	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F0Q04_RS19010	ENOG4105C22	threonyL-tRNA synthetase
F0Q04_RS19030	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F0Q04_RS19035	ENOG4105D01	(LipO)protein
F0Q04_RS19040	ENOG4105VRT	cytoplasmic protein
F0Q04_RS19060	ENOG4105CJ1	ABC, transporter
F0Q04_RS19080	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS19090	ENOG4105CSM	endonuclease III
F0Q04_RS19095	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
F0Q04_RS19105	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
F0Q04_RS19120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F0Q04_RS19125	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
F0Q04_RS19130	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
F0Q04_RS19135	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
F0Q04_RS19140	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
F0Q04_RS19145	ENOG4105EHG	Permease protein
F0Q04_RS19150	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
F0Q04_RS19155	ENOG4108YZT	Adenosylcobinamide kinase
F0Q04_RS19160	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
F0Q04_RS19165	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0Q04_RS19180	ENOG4105HF0	Membrane
F0Q04_RS19185	ENOG4105D4P	Coproporphyrinogen iii oxidase
F0Q04_RS19190	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F0Q04_RS19195	ENOG4107YZX	Universal stress protein
F0Q04_RS19200	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS19205	ENOG41060WC	Enoyl-CoA hydratase
F0Q04_RS19220	ENOG4105DRR	Transcriptional regulator, GntR family
F0Q04_RS19225	ENOG4105E89	ABC transporter
F0Q04_RS19230	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
F0Q04_RS19235	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0Q04_RS19240	ENOG4105GJM	(LipO)protein
F0Q04_RS19255	ENOG4105EZE	Cupin 4 family protein
F0Q04_RS19260	ENOG4108YZY	peptidylprolyl cis-trans isomerase
F0Q04_RS19325	ENOG4105C6Z	Gluconate
F0Q04_RS19350	ENOG4105VT2	5-hydroxyisourate hydrolase
F0Q04_RS19355	ENOG4107YCY	Transcriptional regulator
F0Q04_RS19370	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F0Q04_RS19375	ENOG4105C2W	permease
F0Q04_RS19380	ENOG4105C6K	Malic enzyme
F0Q04_RS19390	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
F0Q04_RS19400	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS19405	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS19425	ENOG4105EW6	flavin reductase domain protein, FMN-binding
F0Q04_RS19430	ENOG4107Z6I	Thiamine biosynthesis protein
F0Q04_RS19440	ENOG4105D7T	ABC transporter
F0Q04_RS19445	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS19470	ENOG4107YCY	Transcriptional regulator
F0Q04_RS19480	ENOG4107T0X	DNA ligase
F0Q04_RS19485	ENOG4107T0X	DNA ligase
F0Q04_RS19490	ENOG4107QRT	dEAD DEAH box helicase
F0Q04_RS19510	ENOG4105C6Z	Gluconate
F0Q04_RS19515	ENOG4105ZXK	Dehydrogenase
F0Q04_RS19525	ENOG4105FB2	class II Aldolase
F0Q04_RS19530	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
F0Q04_RS19565	ENOG41079KZ	Major Facilitator Superfamily
F0Q04_RS19575	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0Q04_RS19585	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
F0Q04_RS19645	ENOG4107QHF	type ii secretion system protein e
F0Q04_RS19665	ENOG4105EYA	deoxyribonuclease
F0Q04_RS19670	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F0Q04_RS19675	ENOG4105D60	lipoprotein releasing system transmembrane protein
F0Q04_RS19685	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F0Q04_RS19690	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0Q04_RS19700	ENOG4108RYR	transcriptional regulator AsnC family
F0Q04_RS19705	ENOG4105CDA	abc transporter atp-binding protein
F0Q04_RS19710	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS19720	ENOG4105DB7	PHP domain protein
F0Q04_RS19725	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
F0Q04_RS19730	ENOG4108Z4T	Peptidase M50
F0Q04_RS19735	ENOG4105C31	Tryptophanyl-tRNA synthetase
F0Q04_RS19740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0Q04_RS19750	ENOG4105BZU	Histidine kinase
F0Q04_RS19755	ENOG4107RGD	Major Facilitator superfamily
F0Q04_RS19760	ENOG4105CSA	Coproporphyrinogen iii oxidase
F0Q04_RS19765	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F0Q04_RS19775	ENOG4105D9P	serine threonine protein kinase
F0Q04_RS19780	ENOG4105DSJ	YicC domain protein
F0Q04_RS19785	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
F0Q04_RS19790	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
F0Q04_RS19795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F0Q04_RS19800	ENOG4108RRZ	Transcription elongation factor GreB
F0Q04_RS19805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS19810	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
F0Q04_RS19870	ENOG4105N14	lysine exporter protein LysE YggA
F0Q04_RS19875	ENOG4108MGI	Transcriptional regulator
F0Q04_RS19880	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
F0Q04_RS19910	ENOG4105DG7	nitrate ABC transporter
F0Q04_RS19950	ENOG4108JQ6	ABC transporter
F0Q04_RS19955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS19985	ENOG4105CJ2	(LipO)protein
F0Q04_RS20005	ENOG4107E2E	PKHD-type hydroxylase
F0Q04_RS20010	ENOG4108IU3	tonb-dependent siderophore receptor
F0Q04_RS20025	ENOG4107MMM	Anti-sigma-factor antagonist
F0Q04_RS20030	ENOG4105FUA	antagonist
F0Q04_RS20045	ENOG4105BZU	Histidine kinase
F0Q04_RS20055	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0Q04_RS20075	ENOG4108NST	exported protein
F0Q04_RS20215	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS20220	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS20225	ENOG4108IPT	Naphthoate synthase
F0Q04_RS20230	ENOG4105CHR	reductase
F0Q04_RS20235	ENOG4108SY4	MarR family Transcriptional regulator
F0Q04_RS20265	ENOG4105C0H	protease
F0Q04_RS20285	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F0Q04_RS20290	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F0Q04_RS20295	ENOG4105CHR	reductase
F0Q04_RS20300	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F0Q04_RS20305	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F0Q04_RS20310	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
F0Q04_RS20315	ENOG4105VGS	50s ribosomal protein l32
F0Q04_RS20320	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
F0Q04_RS20325	ENOG4108UHJ	MAF-like protein
F0Q04_RS20330	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
F0Q04_RS20335	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F0Q04_RS20350	ENOG4105EI2	Pseudouridine synthase
F0Q04_RS20355	ENOG4105C03	ribonuclease
F0Q04_RS20360	ENOG4105D1Q	UPF0246 protein
F0Q04_RS20370	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
F0Q04_RS20375	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F0Q04_RS20380	ENOG4105CSH	Transporter
F0Q04_RS20390	ENOG4105DMF	Dehydrogenase
F0Q04_RS20395	ENOG4105DAA	L-lactate
F0Q04_RS20405	ENOG4105C7N	Xanthine uracil vitamin C permease
F0Q04_RS20410	ENOG4105C7W	Xanthine dehydrogenase
F0Q04_RS20420	ENOG4105CVE	Lytic murein transglycosylase
F0Q04_RS20425	ENOG4105K8R	UPF0145 protein
F0Q04_RS20430	ENOG4105BZ4	penicillin-binding protein
F0Q04_RS20445	ENOG4105CH7	arginosuccinase
F0Q04_RS20450	ENOG4108HRK	Histidine kinase
F0Q04_RS20455	ENOG4108NEV	two component transcriptional regulator, LytTR family
F0Q04_RS20465	ENOG4105C2M	dna polymerase I
F0Q04_RS20475	ENOG4105CUV	Homoserine Kinase
F0Q04_RS20490	ENOG4105C4R	Atp-dependent dna helicase
F0Q04_RS20495	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
F0Q04_RS20510	ENOG41080T7	secreted protein
F0Q04_RS20525	ENOG4105C2C	drug resistance transporter, Bcr CflA
F0Q04_RS20530	ENOG4105C1J	atp-dependent rna helicase
F0Q04_RS20540	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
F0Q04_RS20545	ENOG4105D0M	Protease HtpX homolog
F0Q04_RS20550	ENOG41090A4	Pterin carbinolamine dehydratase
F0Q04_RS20555	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F0Q04_RS20560	ENOG4105EXG	Transcriptional regulator
F0Q04_RS20565	ENOG4105F27	Major Facilitator
F0Q04_RS20570	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
F0Q04_RS20575	ENOG4105P8F	nudix hydrolase
F0Q04_RS20580	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F0Q04_RS20585	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F0Q04_RS20590	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F0Q04_RS20595	ENOG4105K5M	30s ribosomal protein S16
F0Q04_RS20615	ENOG4107QXV	Phosphate transporter
F0Q04_RS20620	ENOG4107GRR	phosphate transport regulator
F0Q04_RS20625	ENOG4108IV0	ABC, transporter
F0Q04_RS20630	ENOG4105C0Z	ABC transporter
F0Q04_RS20635	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
F0Q04_RS20640	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS20645	ENOG4105C10	Electron transfer flavoprotein
F0Q04_RS20650	ENOG4105BZJ	Electron transfer flavoprotein
F0Q04_RS20655	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
F0Q04_RS20660	ENOG4105CGU	Enoyl-CoA hydratase
F0Q04_RS20665	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS20670	ENOG4105CC9	acyl-Coa dehydrogenase
F0Q04_RS20675	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS20680	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0Q04_RS20685	ENOG4105CBN	LysR family transcriptional regulator
F0Q04_RS20705	ENOG4105ECM	Sensor protein basS pmrB
F0Q04_RS20710	ENOG4105FFC	UPF0187 protein
F0Q04_RS20730	ENOG4105D1H	recombination factor protein RarA
F0Q04_RS20735	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
F0Q04_RS20740	ENOG4105DWT	malate dehydrogenase (quinone)
F0Q04_RS20745	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
F0Q04_RS20750	ENOG4105CNU	cell division protein FtsK
F0Q04_RS20755	ENOG4105C3M	thioredoxin reductase
F0Q04_RS20760	ENOG4105KDC	50s ribosomal protein l28
F0Q04_RS20765	ENOG4105W0E	50S ribosomal protein L33
F0Q04_RS20770	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS20795	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F0Q04_RS20800	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F0Q04_RS20810	ENOG4105DTN	riboflavin biosynthesis protein ribF
F0Q04_RS20815	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F0Q04_RS20820	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
F0Q04_RS20825	ENOG4105EAM	Na Pi-cotransporter
F0Q04_RS20835	ENOG4105DFP	Integrase
F0Q04_RS20855	ENOG4105DVF	Cytosine-specific methyltransferase
F0Q04_RS21085	ENOG4105ED4	portal protein
F0Q04_RS21130	ENOG4105CPQ	Dehydrogenase
F0Q04_RS21150	ENOG4105C26	Dehydrogenase
F0Q04_RS21160	ENOG4105CXK	mandelate racemase muconate lactonizing
F0Q04_RS21165	ENOG4105CSP	Major Facilitator Superfamily
F0Q04_RS21185	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
F0Q04_RS21190	ENOG4105DQ4	alcohol dehydrogenase
F0Q04_RS21200	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F0Q04_RS21210	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
F0Q04_RS21215	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
F0Q04_RS21220	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F0Q04_RS21225	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
F0Q04_RS21235	ENOG4105CEN	a g-specific adenine glycosylase
F0Q04_RS21240	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F0Q04_RS21255	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
F0Q04_RS21265	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F0Q04_RS21270	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
F0Q04_RS21275	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F0Q04_RS21280	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F0Q04_RS21290	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0Q04_RS21300	ENOG4108JQ7	(ABC) transporter
F0Q04_RS21305	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0Q04_RS21310	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F0Q04_RS21320	ENOG410829K	Lysine exporter protein (Lyse ygga)
F0Q04_RS21335	ENOG4105EUJ	GTP cyclohydrolase i
F0Q04_RS21340	ENOG4105X23	Endonuclease Exonuclease phosphatase
F0Q04_RS21355	ENOG4105C9M	aspartyl-trna synthetase
F0Q04_RS21375	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F0Q04_RS21390	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F0Q04_RS21415	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
F0Q04_RS21430	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
F0Q04_RS21450	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F0Q04_RS21455	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F0Q04_RS21475	ENOG4105C37	(CBS) domain
F0Q04_RS21485	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F0Q04_RS21490	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F0Q04_RS21495	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F0Q04_RS21500	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0Q04_RS21505	ENOG4105K46	50S ribosomal protein l27
F0Q04_RS21510	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
F0Q04_RS21515	ENOG4105EAH	synthase
F0Q04_RS21520	ENOG4107QHF	type ii secretion system protein e
F0Q04_RS21535	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F0Q04_RS21540	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
F0Q04_RS21545	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
F0Q04_RS21560	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
F0Q04_RS21565	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F0Q04_RS21580	ENOG4105KB2	stringent starvation protein b
F0Q04_RS21585	ENOG4107MKT	Stringent starvation protein a
F0Q04_RS21590	ENOG4105EIX	cytochrome c1
F0Q04_RS21595	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F0Q04_RS21600	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F0Q04_RS21605	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
F0Q04_RS21610	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F0Q04_RS21615	ENOG4107QNR	UPF0135 protein
F0Q04_RS21620	ENOG4105CSH	Transporter
F0Q04_RS21630	ENOG4105C0H	protease
F0Q04_RS21635	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F0Q04_RS21640	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
F0Q04_RS21645	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F0Q04_RS21650	ENOG4105K59	histidine triad (HIT) protein
F0Q04_RS21665	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
F0Q04_RS21670	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
F0Q04_RS21680	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
F0Q04_RS21690	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
F0Q04_RS21700	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F0Q04_RS21705	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F0Q04_RS21720	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F0Q04_RS21735	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F0Q04_RS21745	ENOG4105E3A	(ABC) transporter
F0Q04_RS21750	ENOG4105DA5	(ABC) transporter
F0Q04_RS21770	ENOG4107PE3	Mammalian cell entry related domain protein
F0Q04_RS21775	ENOG4105CY3	ABC transporter, permease
F0Q04_RS21780	ENOG4105DHJ	ABC, transporter
F0Q04_RS21785	ENOG4105CDA	abc transporter atp-binding protein
F0Q04_RS21790	ENOG4105E5Q	amino acid AbC transporter
F0Q04_RS21795	ENOG4108HW3	(ABC) transporter
F0Q04_RS21810	ENOG4105N14	lysine exporter protein LysE YggA
F0Q04_RS21815	ENOG4105C4W	S-formylglutathione hydrolase
F0Q04_RS21820	ENOG4105C1J	atp-dependent rna helicase
F0Q04_RS21850	ENOG4105E0K	tonB-dependent siderophore receptor
F0Q04_RS21855	ENOG4107HP6	Transcriptional regulator
F0Q04_RS21865	ENOG4107QNJ	CoA-transferase subunit B
F0Q04_RS21870	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS21875	ENOG4105F2Z	3-oxoadipate enol-lactonase
F0Q04_RS21895	ENOG4105CRW	Short chain fatty acid transporter
F0Q04_RS21920	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
F0Q04_RS21925	ENOG4105D49	3-dehydroquinate synthase
F0Q04_RS21930	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F0Q04_RS21940	ENOG4105E4G	Type IV pilus
F0Q04_RS21965	ENOG4108JQC	penicillin-binding protein 1A
F0Q04_RS21970	ENOG4105XQ6	frataxin-like protein
F0Q04_RS22000	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F0Q04_RS22005	ENOG4105D1S	lipid A biosynthesis
F0Q04_RS22015	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F0Q04_RS22030	ENOG4107RH7	Nicotinate phosphoribosyltransferase
F0Q04_RS22050	ENOG4107T4Z	adenosine kinase
F0Q04_RS22060	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F0Q04_RS22065	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F0Q04_RS22070	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F0Q04_RS22085	ENOG4105DFU	Cell wall formation (By similarity)
F0Q04_RS22105	ENOG4105GR3	Histidine kinase
F0Q04_RS22120	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F0Q04_RS22125	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
F0Q04_RS22130	ENOG4105CNI	cell division protein FtsW
F0Q04_RS22135	ENOG4105IPS	esterase
F0Q04_RS22150	ENOG4105E2X	shikimate dehydrogenase
F0Q04_RS22160	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
F0Q04_RS22175	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0Q04_RS22180	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F0Q04_RS22185	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F0Q04_RS22190	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
F0Q04_RS22195	ENOG4105CPF	Cell wall formation (By similarity)
F0Q04_RS22200	ENOG4105DFU	Cell wall formation (By similarity)
F0Q04_RS22205	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F0Q04_RS22210	ENOG4105CNI	cell division protein FtsW
F0Q04_RS22215	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F0Q04_RS22220	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
F0Q04_RS22225	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
F0Q04_RS22230	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F0Q04_RS22245	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F0Q04_RS22250	ENOG4108V6E	Cell division protein mraZ
F0Q04_RS22255	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
F0Q04_RS22260	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
F0Q04_RS22275	ENOG4105CKI	cobalamin synthesis protein
F0Q04_RS22285	ENOG4105EB3	Histidine kinase
F0Q04_RS22290	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F0Q04_RS22350	ENOG4108JPW	Aminotransferase
F0Q04_RS22355	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F0Q04_RS22360	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F0Q04_RS22365	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
F0Q04_RS22375	ENOG4108J6E	Pfam:Phage_integr_N
F0Q04_RS22405	ENOG4105CK7	Sodium proline symporter
F0Q04_RS22430	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F0Q04_RS22435	ENOG4108Z9W	Outer membrane porin
F0Q04_RS22440	ENOG4105CSH	Transporter
F0Q04_RS22460	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
F0Q04_RS22465	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
F0Q04_RS22480	ENOG4105CGU	Enoyl-CoA hydratase
F0Q04_RS22485	ENOG4107QX3	carboxylase
F0Q04_RS22490	ENOG4105EEQ	Na H antiporter
F0Q04_RS22495	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS22520	ENOG4108IV0	ABC, transporter
F0Q04_RS22525	ENOG4105C0Z	ABC transporter
F0Q04_RS22530	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS22535	ENOG4105CP9	extracellular ligand-binding receptor
F0Q04_RS22545	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
F0Q04_RS22550	ENOG4105K5B	UPF0225 protein
F0Q04_RS22635	ENOG4105C5H	ABC transporter
F0Q04_RS22640	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS22650	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F0Q04_RS22655	ENOG4108TGY	Glutathione S-transferase
F0Q04_RS22665	ENOG4105JAB	phenazine biosynthesis protein, phzf family
F0Q04_RS22675	ENOG4105C7B	Threonine dehydratase
F0Q04_RS22685	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
F0Q04_RS22690	ENOG4105C26	Dehydrogenase
F0Q04_RS22705	ENOG4108JJ7	ABC transporter
F0Q04_RS22710	ENOG4105NAU	thioesterase Superfamily protein
F0Q04_RS22720	ENOG4108VUY	thioesterase Superfamily protein
F0Q04_RS22740	ENOG4105E39	Enoyl-CoA hydratase
F0Q04_RS22750	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS22755	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
F0Q04_RS22770	ENOG4105CSU	acyl-Coa dehydrogenase
F0Q04_RS22780	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
F0Q04_RS22785	ENOG4105CAS	nag kinase
F0Q04_RS22825	ENOG4105EY8	ABC transporter
F0Q04_RS22835	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
F0Q04_RS22850	ENOG4105GVR	general secretion pathway protein D
F0Q04_RS22885	ENOG4105WMT	general secretion pathway protein h
F0Q04_RS22890	ENOG4108VAU	general secretion pathway protein G
F0Q04_RS22895	ENOG4105D7Q	type ii secretion system
F0Q04_RS22900	ENOG4107QHF	type ii secretion system protein e
F0Q04_RS22905	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F0Q04_RS22915	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
F0Q04_RS22925	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
F0Q04_RS22930	ENOG4109066	lysm domain bon superfamily protein
F0Q04_RS22940	ENOG4105EY8	ABC transporter
F0Q04_RS22970	ENOG4105C25	Primosomal protein n'
F0Q04_RS23000	ENOG4105C4R	Atp-dependent dna helicase
F0Q04_RS23010	ENOG4105HDD	phospholipase
F0Q04_RS23030	ENOG4108IV0	ABC, transporter
F0Q04_RS23035	ENOG4105C0Z	ABC transporter
F0Q04_RS23045	ENOG4105C32	Amino acid ABC transporter (Permease)
F0Q04_RS23060	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS23065	ENOG4108UKI	Enoyl-CoA hydratase
F0Q04_RS23070	ENOG4105DTD	Dehydrogenase
F0Q04_RS23090	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F0Q04_RS23095	ENOG4105BZU	Histidine kinase
F0Q04_RS23115	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
F0Q04_RS23125	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
F0Q04_RS23175	ENOG4108ZT0	50S ribosomal protein l17
F0Q04_RS23180	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0Q04_RS23185	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F0Q04_RS23190	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
F0Q04_RS23195	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0Q04_RS23205	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
F0Q04_RS23210	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F0Q04_RS23215	ENOG4105VPB	50S ribosomal protein L30
F0Q04_RS23220	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
F0Q04_RS23225	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
F0Q04_RS23230	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
F0Q04_RS23235	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F0Q04_RS23240	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F0Q04_RS23245	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0Q04_RS23250	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F0Q04_RS23255	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
F0Q04_RS23265	ENOG4105E98	transcriptional regulator DeoR family
F0Q04_RS23270	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
F0Q04_RS23275	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F0Q04_RS23285	ENOG4105II7	pyrroline-5-carboxylate reductase
F0Q04_RS23290	ENOG4105CXT	aspartate transcarbamylase
F0Q04_RS23300	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
F0Q04_RS23305	ENOG410841Q	phosphoesterase PA-phosphatase related protein
F0Q04_RS23315	ENOG4105CB5	ATP-dependent DNA helicase recG
F0Q04_RS23320	ENOG4105E90	ABC transporter
F0Q04_RS23325	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F0Q04_RS23335	ENOG4108IPW	abc transporter atp-binding protein
F0Q04_RS23340	ENOG4105CM4	permease protein
F0Q04_RS23345	ENOG4105DHS	permease protein
F0Q04_RS23360	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0Q04_RS23370	ENOG4105F04	LysR family Transcriptional regulator
F0Q04_RS23375	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
F0Q04_RS23380	ENOG4105E93	esterase
F0Q04_RS23385	ENOG4105M0Y	
F0Q04_RS23390	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F0Q04_RS23395	ENOG4107QYG	anthranilate phosphoribosyltransferase
F0Q04_RS23405	ENOG4105DDQ	anthranilate synthase
F0Q04_RS23420	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
F0Q04_RS23425	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F0Q04_RS23460	ENOG4105DJV	ribulose-phosphate 3-epimerase
F0Q04_RS23465	ENOG4105NWN	ApaG protein
F0Q04_RS23475	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
F0Q04_RS23480	ENOG4108ZAI	phosphatidylglycerophosphatase a
F0Q04_RS23485	ENOG4107TH8	cina domain protein
F0Q04_RS23505	ENOG4106RHG	Yeca family
F0Q04_RS23510	ENOG4105CBC	glutamate synthase
F0Q04_RS23520	ENOG4105CK2	sodium dicarboxylate symporter
F0Q04_RS23540	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS23550	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS23570	ENOG4105CEY	Amp-dependent synthetase and ligase
F0Q04_RS23575	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
F0Q04_RS23580	ENOG4108UKI	Enoyl-CoA hydratase
F0Q04_RS23610	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F0Q04_RS23625	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
F0Q04_RS23640	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0Q04_RS23645	ENOG4108IUZ	ABC transporter
F0Q04_RS23650	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
F0Q04_RS23670	ENOG4105C75	arginyL-tRNA synthetase
F0Q04_RS23690	ENOG4108KXV	response regulator
F0Q04_RS23710	ENOG4107QP3	malate synthase g
F0Q04_RS23750	ENOG4105CTX	dehydratase
F0Q04_RS23760	ENOG4105EQX	glucarate dehydratase
F0Q04_RS23765	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0Q04_RS23775	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0Q04_RS23785	ENOG4105E9Z	Nad-dependent epimerase dehydratase
F0Q04_RS23795	ENOG4107RP9	extracellular solute-binding protein, family 3
F0Q04_RS23800	ENOG4105DRR	Transcriptional regulator, GntR family
F0Q04_RS23810	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
F0Q04_RS23815	ENOG4105C5I	Dehydrogenase
F0Q04_RS23820	ENOG4105C26	Dehydrogenase
F0Q04_RS23840	ENOG4105E7A	Glutamine amidotransferase
F0Q04_RS23845	ENOG4105C1G	acyl-Coa dehydrogenase
F0Q04_RS23850	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
F0Q04_RS23865	ENOG4105CHU	acetyl-coa acetyltransferase
F0Q04_RS23870	ENOG41077A9	carbonic anhydrase
F0Q04_RS23875	ENOG4105C1G	acyl-Coa dehydrogenase