locus-tag	class	description
FOZ74_RS00015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOZ74_RS00030	COG2816	NAD+ diphosphatase activity
FOZ74_RS00035	COG0425	Belongs to the sulfur carrier protein TusA family
FOZ74_RS00045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOZ74_RS00050	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOZ74_RS00055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOZ74_RS00065	COG4566	intracellular signal transduction
FOZ74_RS00070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOZ74_RS00090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOZ74_RS00095	COG0167	dihydroorotate dehydrogenase activity
FOZ74_RS00100	COG1126	abc transporter atp-binding protein
FOZ74_RS00105	COG0765	amino acid transport
FOZ74_RS00110	COG4597	amino acid ABC transporter
FOZ74_RS00115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOZ74_RS00125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOZ74_RS00130	COG0822	iron-sulfur transferase activity
FOZ74_RS00135	COG1104	cysteine desulfurase activity
FOZ74_RS00145	COG0556	nucleotide-excision repair
FOZ74_RS00155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOZ74_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOZ74_RS00165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOZ74_RS00170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOZ74_RS00190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOZ74_RS00195	COG0077	Prephenate dehydratase
FOZ74_RS00195	COG1605	Chorismate mutase
FOZ74_RS00200	COG0287	Prephenate dehydrogenase
FOZ74_RS00205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOZ74_RS00215	COG0776	regulation of translation
FOZ74_RS00225	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOZ74_RS00230	COG2111	Na H antiporter
FOZ74_RS00230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOZ74_RS00235	COG1006	Multisubunit Na H antiporter MnhC subunit
FOZ74_RS00240	COG0651	ATP synthesis coupled electron transport
FOZ74_RS00250	COG2212	antiporter activity
FOZ74_RS00260	COG1959	2 iron, 2 sulfur cluster binding
FOZ74_RS00265	COG2900	Belongs to the SlyX family
FOZ74_RS00270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOZ74_RS00275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOZ74_RS00280	COG2918	glutathione biosynthetic process
FOZ74_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS00300	COG0633	Ferredoxin
FOZ74_RS00310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOZ74_RS00315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOZ74_RS00320	COG0436	Aminotransferase
FOZ74_RS00325	COG0824	Thioesterase
FOZ74_RS00350	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOZ74_RS00365	COG4106	trans-aconitate 2-methyltransferase activity
FOZ74_RS00370	COG0039	L-malate dehydrogenase activity
FOZ74_RS00375	COG2188	Transcriptional regulator
FOZ74_RS00385	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOZ74_RS00390	COG1053	succinate dehydrogenase
FOZ74_RS00395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOZ74_RS00400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOZ74_RS00405	COG0372	Belongs to the citrate synthase family
FOZ74_RS00410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOZ74_RS00420	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS00435	COG1024	Enoyl-CoA hydratase
FOZ74_RS00445	COG0714	Associated with various cellular activities
FOZ74_RS00465	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOZ74_RS00470	COG3278	Belongs to the heme-copper respiratory oxidase family
FOZ74_RS00480	COG2010	Cytochrome c
FOZ74_RS00505	COG0525	valine-tRNA ligase activity
FOZ74_RS00510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOZ74_RS00515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOZ74_RS00520	COG1674	ftsk spoiiie
FOZ74_RS00525	COG0492	ferredoxin-NADP+ reductase activity
FOZ74_RS00535	COG1538	Outer membrane efflux protein
FOZ74_RS00550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOZ74_RS00575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOZ74_RS00580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOZ74_RS00595	COG0732	type I restriction modification DNA specificity domain
FOZ74_RS00600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOZ74_RS00610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOZ74_RS00620	COG0242	peptide deformylase activity
FOZ74_RS00625	COG2832	Protein of unknown function (DUF454)
FOZ74_RS00650	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOZ74_RS00655	COG1122	ATPase activity
FOZ74_RS00660	COG0697	spore germination
FOZ74_RS00665	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS00675	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOZ74_RS00680	COG0509	glycine decarboxylation via glycine cleavage system
FOZ74_RS00685	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOZ74_RS00685	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOZ74_RS00690	COG0545	Peptidyl-prolyl cis-trans isomerase
FOZ74_RS00700	COG0564	pseudouridine synthase activity
FOZ74_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS00720	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS00725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOZ74_RS00730	COG1082	Xylose isomerase domain protein TIM barrel
FOZ74_RS00735	COG1854	S-ribosylhomocysteine lyase activity
FOZ74_RS00745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOZ74_RS00760	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS00775	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS00820	COG1309	transcriptional regulator
FOZ74_RS00830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOZ74_RS00835	COG1131	(ABC) transporter
FOZ74_RS00840	COG0842	Transport permease protein
FOZ74_RS00845	COG0842	Transport permease protein
FOZ74_RS00855	COG1454	alcohol dehydrogenase
FOZ74_RS00865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOZ74_RS00870	COG1611	Belongs to the LOG family
FOZ74_RS00890	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FOZ74_RS00935	COG1477	protein flavinylation
FOZ74_RS00945	COG3038	cytochrome b561
FOZ74_RS00980	COG0142	geranyltranstransferase activity
FOZ74_RS00985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOZ74_RS00990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOZ74_RS00995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOZ74_RS01000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOZ74_RS01005	COG0494	nUDIX hydrolase
FOZ74_RS01010	COG0442	prolyl-tRNA aminoacylation
FOZ74_RS01015	COG0741	lytic transglycosylase activity
FOZ74_RS01020	COG1253	flavin adenine dinucleotide binding
FOZ74_RS01025	COG0697	spore germination
FOZ74_RS01050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOZ74_RS01055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOZ74_RS01065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOZ74_RS01075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOZ74_RS01080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOZ74_RS01085	COG0196	riboflavin kinase activity
FOZ74_RS01095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOZ74_RS01100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOZ74_RS01105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOZ74_RS01115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOZ74_RS01120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOZ74_RS01125	COG1534	Rna-binding protein
FOZ74_RS01145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOZ74_RS01155	COG0259	pyridoxamine-phosphate oxidase activity
FOZ74_RS01160	COG0322	excinuclease ABC activity
FOZ74_RS01190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOZ74_RS01215	COG0285	dihydrofolate synthase activity
FOZ74_RS01220	COG1393	Belongs to the ArsC family
FOZ74_RS01230	COG0137	argininosuccinate synthase activity
FOZ74_RS01245	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOZ74_RS01250	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOZ74_RS01255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOZ74_RS01260	COG1666	GTP binding
FOZ74_RS01265	COG3577	Aspartyl protease
FOZ74_RS01275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOZ74_RS01285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOZ74_RS01310	COG3549	Plasmid maintenance system killer
FOZ74_RS01340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOZ74_RS01345	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOZ74_RS01385	COG1047	Peptidyl-prolyl cis-trans
FOZ74_RS01395	COG0756	dUTP diphosphatase activity
FOZ74_RS01405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOZ74_RS01475	COG2944	sequence-specific DNA binding
FOZ74_RS01530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOZ74_RS01540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOZ74_RS01545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOZ74_RS01550	COG0271	Belongs to the BolA IbaG family
FOZ74_RS01555	COG0842	Transport permease protein
FOZ74_RS01560	COG1131	(ABC) transporter
FOZ74_RS01575	COG2853	Lipoprotein
FOZ74_RS01580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOZ74_RS01585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOZ74_RS01590	COG1127	ABC transporter
FOZ74_RS01595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOZ74_RS01600	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOZ74_RS01625	COG0589	response to stress
FOZ74_RS01640	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOZ74_RS01640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOZ74_RS01650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOZ74_RS01680	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FOZ74_RS01685	COG0670	Belongs to the BI1 family
FOZ74_RS01695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOZ74_RS01705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOZ74_RS01710	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS01720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOZ74_RS01725	COG0601	transmembrane transport
FOZ74_RS01730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOZ74_RS01735	COG0444	Belongs to the ABC transporter superfamily
FOZ74_RS01740	COG4608	Belongs to the ABC transporter superfamily
FOZ74_RS01745	COG0747	negative chemotaxis
FOZ74_RS01750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOZ74_RS01755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOZ74_RS01755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOZ74_RS01760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOZ74_RS01765	COG1573	uracil-dna glycosylase
FOZ74_RS01775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOZ74_RS01780	COG0505	Belongs to the CarA family
FOZ74_RS01790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOZ74_RS01795	COG0288	reversible hydration of carbon dioxide
FOZ74_RS01820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOZ74_RS01845	COG2010	Cytochrome c
FOZ74_RS01850	COG0737	Belongs to the 5'-nucleotidase family
FOZ74_RS01940	COG0300	oxidoreductase activity
FOZ74_RS01945	COG2259	Doxx family
FOZ74_RS01950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOZ74_RS01955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOZ74_RS01960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOZ74_RS01965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOZ74_RS01970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOZ74_RS01975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOZ74_RS01990	COG0750	zinc metalloprotease
FOZ74_RS01995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOZ74_RS02000	COG0575	Belongs to the CDS family
FOZ74_RS02010	COG0233	cytoplasmic translational termination
FOZ74_RS02015	COG0528	UMP kinase activity
FOZ74_RS02020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOZ74_RS02025	COG0052	Belongs to the universal ribosomal protein uS2 family
FOZ74_RS02030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOZ74_RS02030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOZ74_RS02050	COG0789	Transcriptional regulator
FOZ74_RS02070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOZ74_RS02070	COG1042	CoA-binding domain protein
FOZ74_RS02070	COG0045	succinate-CoA ligase (ADP-forming) activity
FOZ74_RS02090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOZ74_RS02095	COG3191	aminopeptidase activity
FOZ74_RS02100	COG1183	phosphatidylcholine synthase activity
FOZ74_RS02105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOZ74_RS02115	COG0028	Belongs to the TPP enzyme family
FOZ74_RS02120	COG1595	DNA-templated transcription, initiation
FOZ74_RS02140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOZ74_RS02150	COG0347	Belongs to the P(II) protein family
FOZ74_RS02165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOZ74_RS02190	COG3384	dioxygenase
FOZ74_RS02195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOZ74_RS02200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOZ74_RS02210	COG1007	ATP synthesis coupled electron transport
FOZ74_RS02225	COG0713	ATP synthesis coupled electron transport
FOZ74_RS02235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOZ74_RS02240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOZ74_RS02245	COG1034	ATP synthesis coupled electron transport
FOZ74_RS02260	COG0649	NAD binding
FOZ74_RS02265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOZ74_RS02270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOZ74_RS02275	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOZ74_RS02290	COG0149	triose-phosphate isomerase activity
FOZ74_RS02295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOZ74_RS02295	COG3321	synthase
FOZ74_RS02295	COG4221	oxidoreductase activity
FOZ74_RS02295	COG0604	alcohol dehydrogenase
FOZ74_RS02300	COG1185	polyribonucleotide nucleotidyltransferase activity
FOZ74_RS02305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOZ74_RS02345	COG1324	tolerance protein
FOZ74_RS02350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOZ74_RS02355	COG1999	signal sequence binding
FOZ74_RS02360	COG0109	protoheme IX farnesyltransferase activity
FOZ74_RS02395	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FOZ74_RS02400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOZ74_RS02410	COG2226	methyltransferase
FOZ74_RS02415	COG1040	competence protein
FOZ74_RS02420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOZ74_RS02425	COG1192	Involved in chromosome partitioning
FOZ74_RS02435	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOZ74_RS02450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOZ74_RS02510	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOZ74_RS02535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOZ74_RS02555	COG2814	Major facilitator Superfamily
FOZ74_RS02560	COG2814	Major facilitator Superfamily
FOZ74_RS02595	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOZ74_RS02600	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOZ74_RS02605	COG3845	ABC transporter
FOZ74_RS02610	COG3447	MASE1 domain protein
FOZ74_RS02610	COG5001	Diguanylate cyclase
FOZ74_RS02610	COG5002	protein histidine kinase activity
FOZ74_RS02615	COG0537	adenosine 5'-monophosphoramidase activity
FOZ74_RS02620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOZ74_RS02625	COG1136	(ABC) transporter
FOZ74_RS02630	COG0071	Belongs to the small heat shock protein (HSP20) family
FOZ74_RS02655	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOZ74_RS02675	COG2204	response regulator
FOZ74_RS02680	COG1473	amidohydrolase
FOZ74_RS02700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOZ74_RS02710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOZ74_RS02715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOZ74_RS02720	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOZ74_RS02725	COG0142	geranyltranstransferase activity
FOZ74_RS02730	COG1722	exodeoxyribonuclease VII activity
FOZ74_RS02770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOZ74_RS02775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOZ74_RS02795	COG0237	dephospho-CoA kinase activity
FOZ74_RS02820	COG0625	glutathione transferase activity
FOZ74_RS02830	COG3275	phosphorelay sensor kinase activity
FOZ74_RS02845	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOZ74_RS02850	COG0028	Belongs to the TPP enzyme family
FOZ74_RS02870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOZ74_RS02880	COG0795	lipopolysaccharide-transporting ATPase activity
FOZ74_RS02885	COG0583	DNA-binding transcription factor activity
FOZ74_RS02890	COG0436	Aminotransferase
FOZ74_RS02895	COG1530	ribonuclease E activity
FOZ74_RS02900	COG0424	maF-like protein
FOZ74_RS02915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOZ74_RS02920	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOZ74_RS02925	COG3657	addiction module killer protein
FOZ74_RS02930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOZ74_RS02935	COG0799	negative regulation of ribosome biogenesis
FOZ74_RS02940	COG0408	coproporphyrinogen oxidase activity
FOZ74_RS02945	COG0151	Belongs to the GarS family
FOZ74_RS02950	COG0217	transcriptional regulatory protein
FOZ74_RS02955	COG0433	COG0433 Predicted ATPase
FOZ74_RS02960	COG1024	Enoyl-CoA hydratase
FOZ74_RS02970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOZ74_RS02985	COG0328	RNA-DNA hybrid ribonuclease activity
FOZ74_RS02990	COG2226	methyltransferase
FOZ74_RS02995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOZ74_RS03000	COG0741	lytic transglycosylase activity
FOZ74_RS03000	COG1388	LysM domain
FOZ74_RS03010	COG0582	viral genome integration into host DNA
FOZ74_RS03060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOZ74_RS03095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOZ74_RS03100	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOZ74_RS03105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOZ74_RS03110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOZ74_RS03115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOZ74_RS03120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOZ74_RS03120	COG0072	phenylalanine-tRNA ligase activity
FOZ74_RS03125	COG0776	regulation of translation
FOZ74_RS03140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOZ74_RS03145	COG0560	Phosphoserine phosphatase
FOZ74_RS03150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOZ74_RS03155	COG1611	Belongs to the LOG family
FOZ74_RS03170	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOZ74_RS03185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOZ74_RS03195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOZ74_RS03210	COG1840	ABC-type Fe3 transport system, periplasmic component
FOZ74_RS03225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOZ74_RS03230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOZ74_RS03240	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS03250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOZ74_RS03255	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS03265	COG0129	dihydroxy-acid dehydratase activity
FOZ74_RS03280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOZ74_RS03300	COG0590	tRNA wobble adenosine to inosine editing
FOZ74_RS03320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOZ74_RS03335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOZ74_RS03340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOZ74_RS03365	COG1538	Outer membrane efflux protein
FOZ74_RS03370	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOZ74_RS03405	COG0101	tRNA pseudouridine synthase activity
FOZ74_RS03410	COG0135	phosphoribosylanthranilate isomerase activity
FOZ74_RS03415	COG0133	tryptophan synthase activity
FOZ74_RS03420	COG0159	tryptophan synthase activity
FOZ74_RS03425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOZ74_RS03430	COG0762	integral membrane protein
FOZ74_RS03440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOZ74_RS03480	COG1472	Belongs to the glycosyl hydrolase 3 family
FOZ74_RS03485	COG0736	holo-[acyl-carrier-protein] synthase activity
FOZ74_RS03495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOZ74_RS03500	COG1381	Involved in DNA repair and RecF pathway recombination
FOZ74_RS03505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOZ74_RS03510	COG0571	ribonuclease III activity
FOZ74_RS03520	COG0681	Belongs to the peptidase S26 family
FOZ74_RS03525	COG0481	GTPase activity
FOZ74_RS03530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOZ74_RS03550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOZ74_RS03555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOZ74_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS03570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOZ74_RS03575	COG0416	fatty acid biosynthetic process
FOZ74_RS03580	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOZ74_RS03585	COG1399	metal-binding, possibly nucleic acid-binding protein
FOZ74_RS03590	COG0424	maF-like protein
FOZ74_RS03595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOZ74_RS03600	COG1024	Enoyl-CoA hydratase
FOZ74_RS03610	COG0616	signal peptide processing
FOZ74_RS03610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOZ74_RS03630	COG1530	ribonuclease E activity
FOZ74_RS03635	COG3022	response to hydroperoxide
FOZ74_RS03645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOZ74_RS03645	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOZ74_RS03650	COG2203	Gaf domain
FOZ74_RS03650	COG4251	negative regulation of phosphorylation
FOZ74_RS03650	COG5001	Diguanylate cyclase
FOZ74_RS03650	COG3706	GGDEF domain
FOZ74_RS03660	COG0840	transmembrane signaling receptor activity
FOZ74_RS03665	COG0840	transmembrane signaling receptor activity
FOZ74_RS03670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOZ74_RS03675	COG1304	FMN binding
FOZ74_RS03680	COG0604	alcohol dehydrogenase
FOZ74_RS03685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOZ74_RS03690	COG0312	modulator of DNA gyrase
FOZ74_RS03695	COG0772	Belongs to the SEDS family
FOZ74_RS03705	COG3150	esterase
FOZ74_RS03715	COG0557	exoribonuclease II activity
FOZ74_RS03725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOZ74_RS03730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOZ74_RS03740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOZ74_RS03760	COG3550	peptidyl-serine autophosphorylation
FOZ74_RS03765	COG3039	Transposase
FOZ74_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS03785	COG5001	Diguanylate cyclase
FOZ74_RS03800	COG3181	Tripartite tricarboxylate transporter family receptor
FOZ74_RS03805	COG0165	Argininosuccinate lyase
FOZ74_RS03810	COG3275	phosphorelay sensor kinase activity
FOZ74_RS03825	COG0412	Dienelactone hydrolase
FOZ74_RS03830	COG2226	methyltransferase
FOZ74_RS03870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOZ74_RS03880	COG3706	GGDEF domain
FOZ74_RS03885	COG0038	chloride channel
FOZ74_RS03890	COG0210	DNA helicase
FOZ74_RS03915	COG0516	GMP reductase activity
FOZ74_RS03925	COG2814	Major facilitator Superfamily
FOZ74_RS03930	COG5001	Diguanylate cyclase
FOZ74_RS03930	COG3447	MASE1 domain protein
FOZ74_RS03930	COG5002	protein histidine kinase activity
FOZ74_RS03935	COG0513	Belongs to the DEAD box helicase family
FOZ74_RS03940	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOZ74_RS03945	COG0501	Belongs to the peptidase M48B family
FOZ74_RS03950	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOZ74_RS03955	COG1162	GTPase activity
FOZ74_RS03960	COG0753	catalase activity
FOZ74_RS03965	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOZ74_RS04010	COG3451	type IV secretory pathway VirB4
FOZ74_RS04020	COG3838	Conjugal transfer protein Trbc
FOZ74_RS04025	COG4962	Type ii secretion system protein e
FOZ74_RS04045	COG0583	DNA-binding transcription factor activity
FOZ74_RS04135	COG0789	Transcriptional regulator
FOZ74_RS04150	COG4959	Type IV secretory pathway protease TraF
FOZ74_RS04200	COG1396	sequence-specific DNA binding
FOZ74_RS04205	COG5489	Protein of unknown function (DUF736)
FOZ74_RS04235	COG0789	Transcriptional regulator
FOZ74_RS04240	COG1999	signal sequence binding
FOZ74_RS04255	COG2217	Heavy metal translocating P-type atpase
FOZ74_RS04290	COG3344	reverse transcriptase
FOZ74_RS04310	COG3621	Patatin-like phospholipase
FOZ74_RS04330	COG4804	nuclease activity
FOZ74_RS04340	COG0335	large ribosomal subunit rRNA binding
FOZ74_RS04345	COG0336	Belongs to the RNA methyltransferase TrmD family
FOZ74_RS04350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOZ74_RS04355	COG0228	four-way junction DNA binding
FOZ74_RS04365	COG0306	phosphate transporter
FOZ74_RS04370	COG1392	Phosphate transport regulator
FOZ74_RS04385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOZ74_RS04385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOZ74_RS04395	COG0436	Aminotransferase
FOZ74_RS04400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOZ74_RS04405	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOZ74_RS04410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOZ74_RS04415	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOZ74_RS04420	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOZ74_RS04430	COG2076	Multidrug Resistance protein
FOZ74_RS04450	COG1126	abc transporter atp-binding protein
FOZ74_RS04455	COG0765	amino acid transport
FOZ74_RS04460	COG0765	amino acid transport
FOZ74_RS04475	COG2358	TRAP transporter, solute receptor (TAXI family
FOZ74_RS04480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOZ74_RS04485	COG0583	DNA-binding transcription factor activity
FOZ74_RS04490	COG0418	dihydroorotase activity
FOZ74_RS04500	COG1178	ABC-type Fe3 transport system permease component
FOZ74_RS04505	COG3842	ATPase activity
FOZ74_RS04510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOZ74_RS04515	COG0540	Belongs to the ATCase OTCase family
FOZ74_RS04520	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FOZ74_RS04525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOZ74_RS04530	COG1678	Uncharacterized ACR, COG1678
FOZ74_RS04540	COG0840	transmembrane signaling receptor activity
FOZ74_RS04560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOZ74_RS04570	COG0138	bifunctional purine biosynthesis protein purh
FOZ74_RS04575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOZ74_RS04580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOZ74_RS04585	COG1238	metal cluster binding
FOZ74_RS04595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOZ74_RS04600	COG4208	sulfate ABC transporter
FOZ74_RS04605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOZ74_RS04610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOZ74_RS04615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOZ74_RS04620	COG1648	precorrin-2 dehydrogenase activity
FOZ74_RS04620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOZ74_RS04625	COG0175	sulfate reduction
FOZ74_RS04635	COG2895	sulfate adenylyltransferase (ATP) activity
FOZ74_RS04650	COG1024	Enoyl-CoA hydratase
FOZ74_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOZ74_RS04670	COG0012	GTP binding
FOZ74_RS04680	COG2030	dehydratase
FOZ74_RS04680	COG1012	belongs to the aldehyde dehydrogenase family
FOZ74_RS04685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FOZ74_RS04695	COG3189	MarR family transcriptional regulator
FOZ74_RS04705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOZ74_RS04740	COG1002	Type II restriction enzyme, methylase subunits
FOZ74_RS04760	COG1280	lysine exporter protein (LysE YggA)
FOZ74_RS04770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOZ74_RS04785	COG1024	Enoyl-CoA hydratase
FOZ74_RS04790	COG2318	DinB family
FOZ74_RS04795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOZ74_RS04805	COG3012	SEC-C Motif Domain Protein
FOZ74_RS04810	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS04830	COG0183	Belongs to the thiolase family
FOZ74_RS04835	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FOZ74_RS04840	COG0288	reversible hydration of carbon dioxide
FOZ74_RS04845	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS04850	COG0789	Transcriptional regulator
FOZ74_RS04885	COG0488	(ABC) transporter
FOZ74_RS04895	COG0747	negative chemotaxis
FOZ74_RS04900	COG3706	GGDEF domain
FOZ74_RS04900	COG5001	Diguanylate cyclase
FOZ74_RS04900	COG4251	negative regulation of phosphorylation
FOZ74_RS04900	COG2203	Gaf domain
FOZ74_RS04905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOZ74_RS04910	COG0730	response to heat
FOZ74_RS04915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOZ74_RS04920	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOZ74_RS04925	COG1702	phosphate starvation-inducible protein PhoH
FOZ74_RS04930	COG0632	four-way junction helicase activity
FOZ74_RS04940	COG2255	four-way junction helicase activity
FOZ74_RS04950	COG3852	Histidine kinase
FOZ74_RS04955	COG2204	response regulator
FOZ74_RS04965	COG0004	ammonium transporteR
FOZ74_RS04970	COG0067	glutamate synthase
FOZ74_RS04970	COG0070	glutamate synthase
FOZ74_RS04970	COG0069	glutamate synthase activity
FOZ74_RS04980	COG0436	Aminotransferase
FOZ74_RS04995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOZ74_RS05000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOZ74_RS05010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOZ74_RS05010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOZ74_RS05030	COG0277	FAD linked oxidase domain protein
FOZ74_RS05040	COG2365	Tyrosine phosphatase family
FOZ74_RS05045	COG1280	lysine exporter protein (LysE YggA)
FOZ74_RS05060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOZ74_RS05075	COG3245	cytochrome
FOZ74_RS05085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOZ74_RS05090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOZ74_RS05095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOZ74_RS05100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOZ74_RS05105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOZ74_RS05110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOZ74_RS05120	COG0356	it plays a direct role in the translocation of protons across the membrane
FOZ74_RS05130	COG2921	Belongs to the UPF0250 family
FOZ74_RS05135	COG0321	lipoyl(octanoyl) transferase activity
FOZ74_RS05155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOZ74_RS05160	COG2197	response regulator
FOZ74_RS05175	COG1716	ATPase activity
FOZ74_RS05175	COG5001	Diguanylate cyclase
FOZ74_RS05180	COG2197	response regulator
FOZ74_RS05195	COG3409	Peptidoglycan-binding domain 1 protein
FOZ74_RS05195	COG3267	Type II secretory pathway component ExeA
FOZ74_RS05215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOZ74_RS05220	COG0662	Cupin 2, conserved barrel domain protein
FOZ74_RS05220	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOZ74_RS05240	COG1215	transferase activity, transferring glycosyl groups
FOZ74_RS05275	COG1045	serine acetyltransferase
FOZ74_RS05285	COG1132	(ABC) transporter
FOZ74_RS05290	COG0297	glycogen (starch) synthase activity
FOZ74_RS05345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOZ74_RS05360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOZ74_RS05365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOZ74_RS05380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOZ74_RS05385	COG0255	Belongs to the universal ribosomal protein uL29 family
FOZ74_RS05390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOZ74_RS05395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOZ74_RS05400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOZ74_RS05405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOZ74_RS05410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOZ74_RS05415	COG0089	rRNA binding
FOZ74_RS05420	COG0088	Forms part of the polypeptide exit tunnel
FOZ74_RS05425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOZ74_RS05430	COG0051	transcription antitermination factor activity, RNA binding
FOZ74_RS05440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOZ74_RS05445	COG0049	tRNA binding
FOZ74_RS05450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOZ74_RS05465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOZ74_RS05480	COG3088	subunit of a heme lyase
FOZ74_RS05490	COG4133	protoheme IX ABC transporter activity
FOZ74_RS05500	COG1686	Belongs to the peptidase S11 family
FOZ74_RS05515	COG1981	membrane
FOZ74_RS05530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOZ74_RS05535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOZ74_RS05540	COG1862	Preprotein translocase
FOZ74_RS05545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOZ74_RS05550	COG0006	proline dipeptidase activity
FOZ74_RS05560	COG0672	)-iron permease
FOZ74_RS05565	COG0469	pyruvate kinase activity
FOZ74_RS05585	COG3077	Addiction module antitoxin, RelB DinJ family
FOZ74_RS05635	COG0406	alpha-ribazole phosphatase activity
FOZ74_RS05640	COG2201	protein-glutamate methylesterase activity
FOZ74_RS05645	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FOZ74_RS05650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOZ74_RS05655	COG0835	chemotaxis
FOZ74_RS05660	COG0643	Histidine kinase
FOZ74_RS05660	COG2198	Histidine kinase
FOZ74_RS05665	COG0745	RESPONSE REGULATOR receiver
FOZ74_RS05680	COG2197	response regulator
FOZ74_RS05690	COG1987	bacterial-type flagellum assembly
FOZ74_RS05695	COG1338	Plays a role in the flagellum-specific transport system
FOZ74_RS05745	COG1766	The M ring may be actively involved in energy transduction
FOZ74_RS05755	COG0792	nuclease activity
FOZ74_RS05795	COG2070	2-Nitropropane dioxygenase
FOZ74_RS05805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOZ74_RS05820	COG1706	bacterial-type flagellum-dependent cell motility
FOZ74_RS05830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOZ74_RS05840	COG4787	bacterial-type flagellum-dependent cell motility
FOZ74_RS05850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOZ74_RS05855	COG1558	bacterial-type flagellum-dependent cell motility
FOZ74_RS05860	COG1815	bacterial-type flagellum-dependent cell motility
FOZ74_RS05880	COG1191	sigma factor activity
FOZ74_RS05905	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOZ74_RS05910	COG0745	RESPONSE REGULATOR receiver
FOZ74_RS05915	COG1360	Flagellar Motor Protein
FOZ74_RS05925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOZ74_RS05940	COG2089	acid synthase
FOZ74_RS05945	COG0028	Belongs to the TPP enzyme family
FOZ74_RS06005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOZ74_RS06025	COG0326	Molecular chaperone. Has ATPase activity
FOZ74_RS06030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOZ74_RS06040	COG3409	Peptidoglycan-binding domain 1 protein
FOZ74_RS06040	COG3267	Type II secretory pathway component ExeA
FOZ74_RS06045	COG1022	Amp-dependent synthetase and ligase
FOZ74_RS06085	COG0840	transmembrane signaling receptor activity
FOZ74_RS06090	COG0589	response to stress
FOZ74_RS06095	COG0343	queuine tRNA-ribosyltransferase activity
FOZ74_RS06130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOZ74_RS06140	COG0519	Catalyzes the synthesis of GMP from XMP
FOZ74_RS06175	COG2372	response to copper ion
FOZ74_RS06175	COG1276	copper resistance
FOZ74_RS06180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOZ74_RS06185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOZ74_RS06190	COG0679	Auxin Efflux Carrier
FOZ74_RS06195	COG0210	DNA helicase
FOZ74_RS06205	COG2823	Periplasmic or secreted lipoprotein
FOZ74_RS06210	COG2084	Dehydrogenase
FOZ74_RS06220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOZ74_RS06230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOZ74_RS06235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOZ74_RS06240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOZ74_RS06255	COG2119	membrane
FOZ74_RS06285	COG2204	response regulator
FOZ74_RS06290	COG5000	phosphorelay sensor kinase activity
FOZ74_RS06300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOZ74_RS06300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOZ74_RS06310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOZ74_RS06315	COG0085	RNA polymerase activity
FOZ74_RS06320	COG0222	ribosome binding
FOZ74_RS06325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOZ74_RS06330	COG0081	regulation of translation
FOZ74_RS06335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOZ74_RS06400	COG0189	ligase activity
FOZ74_RS06405	COG3135	benzoate transporter
FOZ74_RS06410	COG3158	transport of potassium into the cell
FOZ74_RS06425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOZ74_RS06430	COG0569	domain protein
FOZ74_RS06435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOZ74_RS06440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOZ74_RS06450	COG0693	protein deglycase activity
FOZ74_RS06455	COG0300	oxidoreductase activity
FOZ74_RS06470	COG1002	Type II restriction enzyme, methylase subunits
FOZ74_RS06480	COG0352	thiamine-phosphate diphosphorylase activity
FOZ74_RS06485	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOZ74_RS06500	COG1466	dna polymerase III delta subunit
FOZ74_RS06510	COG0495	leucyl-tRNA aminoacylation
FOZ74_RS06535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOZ74_RS06540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOZ74_RS06545	COG0735	belongs to the Fur family
FOZ74_RS06550	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOZ74_RS06560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOZ74_RS06565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOZ74_RS06575	COG3118	belongs to the thioredoxin family
FOZ74_RS06585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOZ74_RS06590	COG0009	L-threonylcarbamoyladenylate synthase
FOZ74_RS06600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOZ74_RS06605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOZ74_RS06610	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOZ74_RS06630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOZ74_RS06635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOZ74_RS06640	COG2011	ABC-type metal ion transport system permease component
FOZ74_RS06645	COG1464	Belongs to the NlpA lipoprotein family
FOZ74_RS06665	COG0625	glutathione transferase activity
FOZ74_RS06685	COG0861	Integral membrane protein TerC family
FOZ74_RS06690	COG1950	PFAM Membrane protein of
FOZ74_RS06695	COG4783	chaperone-mediated protein folding
FOZ74_RS06700	COG0315	cyclic pyranopterin monophosphate synthase activity
FOZ74_RS06705	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS06735	COG3237	CsbD-like
FOZ74_RS06755	COG2197	response regulator
FOZ74_RS06765	COG1228	amidohydrolase
FOZ74_RS06770	COG2986	histidine ammonia-lyase
FOZ74_RS06775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOZ74_RS06800	COG0683	leucine binding
FOZ74_RS06805	COG2188	Transcriptional regulator
FOZ74_RS06810	COG0010	Belongs to the arginase family
FOZ74_RS06815	COG0786	glutamate:sodium symporter activity
FOZ74_RS06825	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS06850	COG1309	transcriptional regulator
FOZ74_RS06865	COG1136	(ABC) transporter
FOZ74_RS06880	COG3038	cytochrome b561
FOZ74_RS06885	COG0791	NLP P60 protein
FOZ74_RS06900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOZ74_RS06905	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOZ74_RS06935	COG1070	Carbohydrate kinase
FOZ74_RS06955	COG0592	DNA-directed DNA polymerase activity
FOZ74_RS06960	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOZ74_RS06965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOZ74_RS06970	COG0594	ribonuclease P activity
FOZ74_RS06975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOZ74_RS06980	COG0706	membrane insertase activity
FOZ74_RS07000	COG0789	Transcriptional regulator
FOZ74_RS07005	COG0482	sulfurtransferase activity
FOZ74_RS07025	COG0284	orotidine-5'-phosphate decarboxylase activity
FOZ74_RS07045	COG0126	phosphoglycerate kinase activity
FOZ74_RS07060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOZ74_RS07070	COG0242	peptide deformylase activity
FOZ74_RS07080	COG0758	DNA mediated transformation
FOZ74_RS07085	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FOZ74_RS07105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOZ74_RS07115	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOZ74_RS07125	COG0850	regulation of cytokinetic process
FOZ74_RS07135	COG2814	Major facilitator Superfamily
FOZ74_RS07140	COG4770	biotin carboxylase activity
FOZ74_RS07145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOZ74_RS07150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOZ74_RS07180	COG1408	metallophosphoesterase
FOZ74_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS07210	COG1950	PFAM Membrane protein of
FOZ74_RS07225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOZ74_RS07235	COG4771	TonB-dependent receptor
FOZ74_RS07245	COG3720	iron ion transport
FOZ74_RS07250	COG4558	Periplasmic binding protein
FOZ74_RS07255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOZ74_RS07260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOZ74_RS07295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOZ74_RS07320	COG3549	Plasmid maintenance system killer
FOZ74_RS07335	COG0598	Magnesium transport protein CorA
FOZ74_RS07340	COG2814	Major facilitator Superfamily
FOZ74_RS07355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOZ74_RS07360	COG1047	Peptidyl-prolyl cis-trans
FOZ74_RS07370	COG2223	nitrite transmembrane transporter activity
FOZ74_RS07380	COG0625	glutathione transferase activity
FOZ74_RS07405	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOZ74_RS07405	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOZ74_RS07415	COG0642	Histidine kinase
FOZ74_RS07430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOZ74_RS07435	COG2137	regulation of response to DNA damage stimulus
FOZ74_RS07440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOZ74_RS07450	COG1309	transcriptional regulator
FOZ74_RS07480	COG1022	Amp-dependent synthetase and ligase
FOZ74_RS07485	COG1024	Enoyl-CoA hydratase
FOZ74_RS07490	COG0183	Belongs to the thiolase family
FOZ74_RS07500	COG0700	Nucleoside recognition
FOZ74_RS07505	COG2974	May be involved in recombination
FOZ74_RS07515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOZ74_RS07520	COG0791	NLP P60 protein
FOZ74_RS07525	COG2258	MOSC domain
FOZ74_RS07530	COG2217	Heavy metal translocating P-type atpase
FOZ74_RS07535	COG0589	response to stress
FOZ74_RS07535	COG0475	glutathione-regulated potassium exporter activity
FOZ74_RS07550	COG1902	pentaerythritol trinitrate reductase activity
FOZ74_RS07555	COG0445	tRNA wobble uridine modification
FOZ74_RS07560	COG0357	Ribosomal RNA small subunit methyltransferase G
FOZ74_RS07565	COG1192	Involved in chromosome partitioning
FOZ74_RS07570	COG1475	DNA binding
FOZ74_RS07610	COG0277	FAD linked oxidase domain protein
FOZ74_RS07615	COG2096	Adenosyltransferase
FOZ74_RS07620	COG2050	protein possibly involved in aromatic compounds catabolism
FOZ74_RS07625	COG2233	PERMEase
FOZ74_RS07635	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FOZ74_RS07650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOZ74_RS07655	COG1137	ATPase activity
FOZ74_RS07660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOZ74_RS07665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOZ74_RS07675	COG0018	arginyl-trna synthetase
FOZ74_RS07695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOZ74_RS07700	COG2354	Protein conserved in bacteria
FOZ74_RS07715	COG2027	D-alanyl-D-alanine carboxypeptidase
FOZ74_RS07720	COG1214	PFAM Peptidase M22, glycoprotease
FOZ74_RS07735	COG0598	Magnesium transport protein CorA
FOZ74_RS07745	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS07750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOZ74_RS07755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOZ74_RS07760	COG0121	glutamine amidotransferase
FOZ74_RS07775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOZ74_RS07780	COG2813	Specifically methylates the guanine in position
FOZ74_RS07780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOZ74_RS07785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOZ74_RS07795	COG3608	succinylglutamate desuccinylase aspartoacylase
FOZ74_RS07795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOZ74_RS07810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOZ74_RS07835	COG2890	protein-(glutamine-N5) methyltransferase activity
FOZ74_RS07885	COG1346	cytolysis
FOZ74_RS07890	COG1380	Effector of murein hydrolase LrgA
FOZ74_RS07920	COG0277	FAD linked oxidase domain protein
FOZ74_RS07925	COG0247	lactate metabolic process
FOZ74_RS07945	COG0477	Major facilitator Superfamily
FOZ74_RS07950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOZ74_RS07990	COG2205	protein histidine kinase activity
FOZ74_RS07995	COG0784	Response regulator, receiver
FOZ74_RS07995	COG2198	Histidine kinase
FOZ74_RS07995	COG2205	protein histidine kinase activity
FOZ74_RS08020	COG0477	Major facilitator Superfamily
FOZ74_RS08025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOZ74_RS08040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOZ74_RS08060	COG0300	oxidoreductase activity
FOZ74_RS08065	COG0724	RNA recognition motif
FOZ74_RS08080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOZ74_RS08085	COG0045	succinate-CoA ligase (ADP-forming) activity
FOZ74_RS08090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOZ74_RS08095	COG0631	protein serine/threonine phosphatase activity
FOZ74_RS08130	COG1199	ATP-dependent helicase activity
FOZ74_RS08160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOZ74_RS08165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOZ74_RS08170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOZ74_RS08180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOZ74_RS08185	COG2267	carboxylic ester hydrolase activity
FOZ74_RS08190	COG0307	riboflavin synthase, alpha
FOZ74_RS08200	COG2205	protein histidine kinase activity
FOZ74_RS08205	COG0745	RESPONSE REGULATOR receiver
FOZ74_RS08210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOZ74_RS08220	COG2211	Major facilitator Superfamily
FOZ74_RS08225	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FOZ74_RS08230	COG0697	spore germination
FOZ74_RS08235	COG0501	Belongs to the peptidase M48B family
FOZ74_RS08240	COG1802	Transcriptional regulator
FOZ74_RS08310	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FOZ74_RS08320	COG0840	transmembrane signaling receptor activity
FOZ74_RS08360	COG1177	transmembrane transport
FOZ74_RS08365	COG3842	ATPase activity
FOZ74_RS08370	COG1840	ABC-type Fe3 transport system, periplasmic component
FOZ74_RS08375	COG0659	secondary active sulfate transmembrane transporter activity
FOZ74_RS08380	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOZ74_RS08390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOZ74_RS08400	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOZ74_RS08405	COG4774	siderophore transport
FOZ74_RS08420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOZ74_RS08440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOZ74_RS08445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOZ74_RS08450	COG1414	Transcriptional regulator
FOZ74_RS08455	COG0583	DNA-binding transcription factor activity
FOZ74_RS08465	COG2159	amidohydrolase
FOZ74_RS08505	COG0683	leucine binding
FOZ74_RS08530	COG0667	Aldo Keto reductase
FOZ74_RS08535	COG0708	Exodeoxyribonuclease III
FOZ74_RS08540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOZ74_RS08550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOZ74_RS08555	COG0154	amidase activity
FOZ74_RS08560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOZ74_RS08565	COG1077	Cell shape determining protein MreB Mrl
FOZ74_RS08570	COG1792	Involved in formation and maintenance of cell shape
FOZ74_RS08580	COG0768	penicillin binding
FOZ74_RS08595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOZ74_RS08600	COG1127	ABC transporter
FOZ74_RS08615	COG2095	MarC family integral membrane protein
FOZ74_RS08620	COG0412	Dienelactone hydrolase
FOZ74_RS08625	COG0840	transmembrane signaling receptor activity
FOZ74_RS08650	COG1566	PFAM secretion protein HlyD family protein
FOZ74_RS08665	COG0840	transmembrane signaling receptor activity
FOZ74_RS08705	COG1546	Belongs to the CinA family
FOZ74_RS08710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOZ74_RS08740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FOZ74_RS08750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOZ74_RS08760	COG0546	phosphoglycolate phosphatase activity
FOZ74_RS08790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOZ74_RS08795	COG0134	indole-3-glycerol-phosphate synthase activity
FOZ74_RS08805	COG3706	GGDEF domain
FOZ74_RS08810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOZ74_RS08825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOZ74_RS08835	COG0783	Belongs to the Dps family
FOZ74_RS08840	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOZ74_RS08850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOZ74_RS08855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOZ74_RS08860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOZ74_RS08865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOZ74_RS08870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOZ74_RS08875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOZ74_RS08880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOZ74_RS08885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOZ74_RS08890	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOZ74_RS08895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOZ74_RS08900	COG1841	ribosomal large subunit assembly
FOZ74_RS08905	COG0200	Binds to the 23S rRNA
FOZ74_RS08910	COG0201	protein transport
FOZ74_RS08915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOZ74_RS08920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOZ74_RS08925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOZ74_RS08930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOZ74_RS08935	COG0202	RNA polymerase activity
FOZ74_RS08940	COG0203	ribosomal protein L17
FOZ74_RS08955	COG2208	phosphoserine phosphatase activity
FOZ74_RS08955	COG2770	Histidine kinase
FOZ74_RS08990	COG4792	protein secretion
FOZ74_RS08995	COG4791	protein targeting
FOZ74_RS09000	COG4794	Type iii secretion
FOZ74_RS09005	COG4790	Type iii secretion
FOZ74_RS09010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOZ74_RS09040	COG4669	(LipO)protein
FOZ74_RS09125	COG4789	Type iii secretion
FOZ74_RS09165	COG0765	amino acid transport
FOZ74_RS09170	COG0765	amino acid transport
FOZ74_RS09180	COG0037	tRNA processing
FOZ74_RS09210	COG3118	belongs to the thioredoxin family
FOZ74_RS09215	COG0617	tRNA 3'-terminal CCA addition
FOZ74_RS09220	COG0625	glutathione transferase activity
FOZ74_RS09225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOZ74_RS09230	COG0741	lytic transglycosylase activity
FOZ74_RS09230	COG1196	nuclear chromosome segregation
FOZ74_RS09230	COG0739	heme binding
FOZ74_RS09245	COG3128	pkhd-type hydroxylase
FOZ74_RS09255	COG4774	siderophore transport
FOZ74_RS09270	COG3186	Phenylalanine-4-hydroxylase
FOZ74_RS09290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOZ74_RS09340	COG0752	glycyl-tRNA synthetase alpha subunit
FOZ74_RS09350	COG0751	glycine-tRNA ligase activity
FOZ74_RS09365	COG1652	LysM domain
FOZ74_RS09370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOZ74_RS09415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOZ74_RS09420	COG1459	type II secretion system
FOZ74_RS09425	COG2165	general secretion pathway protein
FOZ74_RS09435	COG2165	general secretion pathway protein
FOZ74_RS09465	COG1450	Type ii and iii secretion system protein
FOZ74_RS09505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOZ74_RS09520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOZ74_RS09540	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOZ74_RS09580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOZ74_RS09610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOZ74_RS09620	COG1086	Polysaccharide biosynthesis protein
FOZ74_RS09640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOZ74_RS09665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOZ74_RS09675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOZ74_RS09695	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS09705	COG1024	Enoyl-CoA hydratase
FOZ74_RS09705	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOZ74_RS09710	COG2852	Protein conserved in bacteria
FOZ74_RS09715	COG0183	Belongs to the thiolase family
FOZ74_RS09730	COG1024	Enoyl-CoA hydratase
FOZ74_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS09745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOZ74_RS09750	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS09760	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS09765	COG1024	Enoyl-CoA hydratase
FOZ74_RS09775	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS09780	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS09790	COG1335	isochorismatase
FOZ74_RS09795	COG0477	Major facilitator Superfamily
FOZ74_RS09840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOZ74_RS09840	COG1024	Enoyl-CoA hydratase
FOZ74_RS09845	COG0183	Belongs to the thiolase family
FOZ74_RS09850	COG1960	acyl-CoA dehydrogenase activity
FOZ74_RS09905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOZ74_RS09920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOZ74_RS09930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOZ74_RS09935	COG0543	2 iron, 2 sulfur cluster binding
FOZ74_RS09935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOZ74_RS09940	COG5265	(ABC) transporter
FOZ74_RS09945	COG0022	dehydrogenase e1 component
FOZ74_RS09950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOZ74_RS09955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOZ74_RS09960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOZ74_RS09960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOZ74_RS09965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOZ74_RS09970	COG0583	DNA-binding transcription factor activity
FOZ74_RS09975	COG0501	Belongs to the peptidase M48B family
FOZ74_RS10005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOZ74_RS10020	COG0523	cobalamin synthesis protein
FOZ74_RS10035	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOZ74_RS10040	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOZ74_RS10045	COG2001	Belongs to the MraZ family
FOZ74_RS10050	COG0275	rRNA processing
FOZ74_RS10065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOZ74_RS10070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOZ74_RS10075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOZ74_RS10080	COG0772	Belongs to the SEDS family
FOZ74_RS10085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOZ74_RS10090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOZ74_RS10095	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOZ74_RS10100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOZ74_RS10115	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOZ74_RS10120	COG3045	CreA protein
FOZ74_RS10125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOZ74_RS10125	COG0189	ligase activity
FOZ74_RS10130	COG0189	ligase activity
FOZ74_RS10130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOZ74_RS10135	COG1132	(ABC) transporter
FOZ74_RS10160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOZ74_RS10165	COG1881	PFAM PEBP family protein
FOZ74_RS10225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOZ74_RS10240	COG3609	addiction module antidote protein, CC2985 family
FOZ74_RS10265	COG1473	amidohydrolase
FOZ74_RS10270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOZ74_RS10275	COG0166	Belongs to the GPI family
FOZ74_RS10295	COG0028	Belongs to the TPP enzyme family
FOZ74_RS10300	COG1304	FMN binding
FOZ74_RS10305	COG3573	Dehydrogenase
FOZ74_RS10315	COG1017	nitric oxide dioxygenase activity
FOZ74_RS10315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOZ74_RS10320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOZ74_RS10330	COG1704	LemA family
FOZ74_RS10335	COG0501	Belongs to the peptidase M48B family
FOZ74_RS10340	COG2840	Smr protein MutS2
FOZ74_RS10350	COG2003	Belongs to the UPF0758 family
FOZ74_RS10355	COG1047	Peptidyl-prolyl cis-trans
FOZ74_RS10360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOZ74_RS10365	COG1253	flavin adenine dinucleotide binding
FOZ74_RS10370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOZ74_RS10370	COG0617	tRNA 3'-terminal CCA addition
FOZ74_RS10370	COG0517	IMP dehydrogenase activity
FOZ74_RS10375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOZ74_RS10400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOZ74_RS10410	COG0642	Histidine kinase
FOZ74_RS10415	COG1126	abc transporter atp-binding protein
FOZ74_RS10420	COG0765	amino acid transport
FOZ74_RS10425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOZ74_RS10430	COG0583	DNA-binding transcription factor activity
FOZ74_RS10435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOZ74_RS10440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOZ74_RS10445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOZ74_RS10460	COG0316	Belongs to the HesB IscA family
FOZ74_RS10465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOZ74_RS10470	COG0739	heme binding
FOZ74_RS10475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOZ74_RS10480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOZ74_RS10485	COG2205	protein histidine kinase activity
FOZ74_RS10510	COG0697	spore germination
FOZ74_RS10520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOZ74_RS10530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOZ74_RS10535	COG0511	ligase activity, forming carbon-carbon bonds
FOZ74_RS10540	COG0439	Biotin carboxylase
FOZ74_RS10545	COG2264	protein methyltransferase activity
FOZ74_RS10555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOZ74_RS10565	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOZ74_RS10585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOZ74_RS10590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOZ74_RS10600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOZ74_RS10610	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FOZ74_RS10615	COG0489	protein tyrosine kinase activity
FOZ74_RS10620	COG0302	gtp cyclohydrolase
FOZ74_RS10635	COG0653	protein targeting
FOZ74_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
FOZ74_RS10650	COG0583	DNA-binding transcription factor activity
FOZ74_RS10660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOZ74_RS10680	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOZ74_RS10690	COG1012	belongs to the aldehyde dehydrogenase family
FOZ74_RS10695	COG3384	dioxygenase
FOZ74_RS10705	COG3971	2-oxopent-4-enoate hydratase activity
FOZ74_RS10720	COG0028	Belongs to the TPP enzyme family
FOZ74_RS10725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOZ74_RS10730	COG1012	belongs to the aldehyde dehydrogenase family
FOZ74_RS10760	COG1022	Amp-dependent synthetase and ligase
FOZ74_RS10790	COG0180	Tryptophanyl-tRNA synthetase
FOZ74_RS10795	COG1994	Peptidase M50
FOZ74_RS10800	COG5002	protein histidine kinase activity
FOZ74_RS10810	COG0704	Plays a role in the regulation of phosphate uptake
FOZ74_RS10815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOZ74_RS10820	COG0581	inorganic phosphate transmembrane transporter activity
FOZ74_RS10825	COG0573	inorganic phosphate transmembrane transporter activity
FOZ74_RS10830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOZ74_RS10850	COG1522	sequence-specific DNA binding
FOZ74_RS10855	COG0009	L-threonylcarbamoyladenylate synthase
FOZ74_RS10860	COG0613	PHP domain protein
FOZ74_RS10865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOZ74_RS10875	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOZ74_RS10880	COG1136	(ABC) transporter
FOZ74_RS10895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOZ74_RS10905	COG0084	hydrolase, TatD family'
FOZ74_RS10910	COG5001	Diguanylate cyclase
FOZ74_RS10910	COG3706	GGDEF domain
FOZ74_RS10910	COG2203	Gaf domain
FOZ74_RS10910	COG4251	negative regulation of phosphorylation
FOZ74_RS10930	COG1396	sequence-specific DNA binding
FOZ74_RS10930	COG3800	Transcriptional regulator
FOZ74_RS10945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOZ74_RS10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOZ74_RS10960	COG1846	Transcriptional regulator
FOZ74_RS10965	COG1764	response to oxidative stress
FOZ74_RS10975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOZ74_RS10980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOZ74_RS10990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOZ74_RS10995	COG2267	carboxylic ester hydrolase activity
FOZ74_RS11000	COG0697	spore germination
FOZ74_RS11010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOZ74_RS11015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOZ74_RS11020	COG3706	GGDEF domain
FOZ74_RS11025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOZ74_RS11035	COG3622	Belongs to the hyi family
FOZ74_RS11040	COG3228	Belongs to the MtfA family
FOZ74_RS11045	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOZ74_RS11070	COG0215	cysteine-tRNA ligase activity
FOZ74_RS11080	COG0037	tRNA processing
FOZ74_RS11085	COG0527	aspartate kinase activity
FOZ74_RS11135	COG3328	transposase activity
FOZ74_RS11150	COG3039	Transposase
FOZ74_RS11190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOZ74_RS11195	COG3039	Transposase
FOZ74_RS11205	COG0582	viral genome integration into host DNA
FOZ74_RS11210	COG0301	tRNA thio-modification
FOZ74_RS11210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOZ74_RS11215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOZ74_RS11220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOZ74_RS11230	COG1122	ATPase activity
FOZ74_RS11240	COG0534	Mate efflux family protein
FOZ74_RS11250	COG0254	rRNA binding
FOZ74_RS11255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOZ74_RS11270	COG1074	ATP-dependent DNA helicase activity
FOZ74_RS11280	COG0493	'glutamate synthase
FOZ74_RS11280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOZ74_RS11285	COG0835	chemotaxis
FOZ74_RS11285	COG0784	Response regulator, receiver
FOZ74_RS11310	COG4174	ABC transporter (Permease)
FOZ74_RS11325	COG4239	(ABC) transporter, permease
FOZ74_RS11330	COG4172	Belongs to the ABC transporter superfamily
FOZ74_RS11335	COG0589	response to stress
FOZ74_RS11340	COG0628	permease
FOZ74_RS11345	COG0567	Dehydrogenase, E1 component
FOZ74_RS11350	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOZ74_RS11355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOZ74_RS11360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOZ74_RS11365	COG0631	protein serine/threonine phosphatase activity
FOZ74_RS11375	COG0671	phosphoesterase, PA-phosphatase related
FOZ74_RS11385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOZ74_RS11390	COG0542	response to heat
FOZ74_RS11415	COG1832	CoA-binding protein
FOZ74_RS11420	COG2951	lytic endotransglycosylase activity
FOZ74_RS11435	COG2925	Exonuclease
FOZ74_RS11455	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOZ74_RS11460	COG0024	Methionine aminopeptidase
FOZ74_RS11465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOZ74_RS11465	COG0047	phosphoribosylformylglycinamidine synthase activity
FOZ74_RS11475	COG1487	ribonuclease activity
FOZ74_RS11490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOZ74_RS11505	COG4206	TonB-dependent receptor
FOZ74_RS11510	COG1797	cobyrinic acid a,c-diamide synthase activity
FOZ74_RS11520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOZ74_RS11525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOZ74_RS11530	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOZ74_RS11535	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FOZ74_RS11545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOZ74_RS11570	COG1492	cobalamin metabolic process
FOZ74_RS11575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOZ74_RS11580	COG4771	TonB-dependent receptor
FOZ74_RS11585	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FOZ74_RS11600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOZ74_RS11605	COG0668	transmembrane transport
FOZ74_RS11610	COG0657	acetylesterase activity
FOZ74_RS11630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOZ74_RS11635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOZ74_RS11640	COG0470	DNA polymerase III
FOZ74_RS11650	COG0084	hydrolase, TatD family'
FOZ74_RS11660	COG1132	(ABC) transporter
FOZ74_RS11665	COG0823	Involved in the tonB-independent uptake of proteins
FOZ74_RS11670	COG2885	chlorophyll binding
FOZ74_RS11680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOZ74_RS11695	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS11705	COG0612	Peptidase, M16
FOZ74_RS11710	COG0612	Peptidase, M16
FOZ74_RS11715	COG0742	ribosomal rna small subunit methyltransferase
FOZ74_RS11720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOZ74_RS11725	COG0069	glutamate synthase activity
FOZ74_RS11730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOZ74_RS11735	COG0793	Belongs to the peptidase S41A family
FOZ74_RS11740	COG0588	phosphoglycerate mutase activity
FOZ74_RS11745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOZ74_RS11750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOZ74_RS11755	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOZ74_RS11760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOZ74_RS11770	COG0513	Belongs to the DEAD box helicase family
FOZ74_RS11775	COG0488	(ABC) transporter
FOZ74_RS11790	COG1137	ATPase activity
FOZ74_RS11825	COG0625	glutathione transferase activity
FOZ74_RS11835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOZ74_RS11840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOZ74_RS11845	COG0683	leucine binding
FOZ74_RS11850	COG0459	protein refolding
FOZ74_RS11855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOZ74_RS11860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOZ74_RS11865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOZ74_RS11875	COG1560	Kdo2-lipid A biosynthetic process
FOZ74_RS11880	COG1268	BioY protein
FOZ74_RS11885	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOZ74_RS11895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOZ74_RS11900	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOZ74_RS11950	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOZ74_RS11955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOZ74_RS11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOZ74_RS11975	COG0765	amino acid transport
FOZ74_RS11980	COG1126	abc transporter atp-binding protein
FOZ74_RS11985	COG0741	lytic transglycosylase activity
FOZ74_RS11990	COG0484	heat shock protein binding
FOZ74_RS11995	COG0443	Heat shock 70 kDa protein
FOZ74_RS12000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOZ74_RS12005	COG0360	Binds together with S18 to 16S ribosomal RNA
FOZ74_RS12010	COG2965	DNA replication, synthesis of RNA primer
FOZ74_RS12015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOZ74_RS12020	COG0359	binds to the 23S rRNA
FOZ74_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
FOZ74_RS12040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOZ74_RS12045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOZ74_RS12055	COG0436	Aminotransferase
FOZ74_RS12080	COG0303	'Molybdopterin
FOZ74_RS12100	COG0314	molybdopterin synthase activity
FOZ74_RS12110	COG1268	BioY protein
FOZ74_RS12120	COG0542	response to heat
FOZ74_RS12140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOZ74_RS12140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOZ74_RS12170	COG4969	Belongs to the N-Me-Phe pilin family
FOZ74_RS12175	COG4969	Belongs to the N-Me-Phe pilin family
FOZ74_RS12195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOZ74_RS12200	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOZ74_RS12205	COG0308	aminopeptidase N
FOZ74_RS12220	COG0473	3-isopropylmalate dehydrogenase activity
FOZ74_RS12225	COG0066	3-isopropylmalate dehydratase activity
FOZ74_RS12235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOZ74_RS12240	COG3033	Beta-eliminating lyase
FOZ74_RS12265	COG5001	Diguanylate cyclase
FOZ74_RS12265	COG4251	negative regulation of phosphorylation
FOZ74_RS12265	COG3706	GGDEF domain
FOZ74_RS12265	COG2203	Gaf domain
FOZ74_RS12270	COG1132	(ABC) transporter
FOZ74_RS12275	COG4133	protoheme IX ABC transporter activity
FOZ74_RS12280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOZ74_RS12285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOZ74_RS12290	COG0586	Pfam SNARE associated Golgi protein
FOZ74_RS12295	COG0402	S-adenosylhomocysteine deaminase activity
FOZ74_RS12300	COG2252	PERMEase
FOZ74_RS12310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOZ74_RS12335	COG2207	Transcriptional regulator
FOZ74_RS12340	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOZ74_RS12345	COG0802	atpase or kinase
FOZ74_RS12350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOZ74_RS12370	COG2358	TRAP transporter, solute receptor (TAXI family
FOZ74_RS12375	COG4974	Belongs to the 'phage' integrase family
FOZ74_RS12380	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOZ74_RS12385	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOZ74_RS12390	COG2833	Protein of unknown function (DUF455)
FOZ74_RS12400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOZ74_RS12405	COG0840	transmembrane signaling receptor activity
FOZ74_RS12410	COG0583	DNA-binding transcription factor activity
FOZ74_RS12415	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOZ74_RS12420	COG0148	phosphopyruvate hydratase activity
FOZ74_RS12430	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOZ74_RS12435	COG0504	CTP synthase activity
FOZ74_RS12440	COG0840	transmembrane signaling receptor activity
FOZ74_RS12470	COG2003	Belongs to the UPF0758 family
FOZ74_RS12480	COG0582	viral genome integration into host DNA
FOZ74_RS12490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOZ74_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS12515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOZ74_RS12525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOZ74_RS12540	COG0281	malic enzyme
FOZ74_RS12540	COG0280	phosphate acetyltransferase
FOZ74_RS12545	COG2233	PERMEase
FOZ74_RS12550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOZ74_RS12565	COG2186	Transcriptional regulator
FOZ74_RS12615	COG0405	Gamma-glutamyltransferase
FOZ74_RS12635	COG0717	Belongs to the dCTP deaminase family
FOZ74_RS12640	COG2423	ornithine cyclodeaminase activity
FOZ74_RS12645	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FOZ74_RS12650	COG2321	neutral zinc metallopeptidase
FOZ74_RS12655	COG0513	Belongs to the DEAD box helicase family
FOZ74_RS12660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOZ74_RS12665	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOZ74_RS12670	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOZ74_RS12675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOZ74_RS12690	COG0483	inositol monophosphate 1-phosphatase activity
FOZ74_RS12700	COG1045	serine acetyltransferase
FOZ74_RS12705	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOZ74_RS12710	COG0740	serine-type endopeptidase activity
FOZ74_RS12715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOZ74_RS12720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOZ74_RS12750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOZ74_RS12775	COG1058	Belongs to the CinA family
FOZ74_RS12775	COG1546	Belongs to the CinA family
FOZ74_RS12780	COG0174	glutamine synthetase
FOZ74_RS12795	COG0708	Exodeoxyribonuclease III
FOZ74_RS12815	COG3504	Conjugal transfer protein
FOZ74_RS12825	COG3846	protein secretion by the type IV secretion system
FOZ74_RS12835	COG3451	type IV secretory pathway VirB4
FOZ74_RS12845	COG3838	Conjugal transfer protein Trbc
FOZ74_RS12850	COG4962	Type ii secretion system protein e
FOZ74_RS12870	COG0583	DNA-binding transcription factor activity
FOZ74_RS12875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOZ74_RS12945	COG2132	Multicopper oxidase
FOZ74_RS12955	COG2205	protein histidine kinase activity
FOZ74_RS12965	COG2132	Multicopper oxidase
FOZ74_RS12995	COG1192	Involved in chromosome partitioning
FOZ74_RS13030	COG5489	Protein of unknown function (DUF736)
FOZ74_RS13090	COG2003	Belongs to the UPF0758 family
FOZ74_RS13095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOZ74_RS13105	COG3039	Transposase
FOZ74_RS13125	COG1204	response to ionizing radiation
FOZ74_RS13130	COG0582	viral genome integration into host DNA
FOZ74_RS13150	COG3278	Belongs to the heme-copper respiratory oxidase family
FOZ74_RS13170	COG0348	domain, Protein
FOZ74_RS13185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOZ74_RS13210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOZ74_RS13235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOZ74_RS13240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOZ74_RS13245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOZ74_RS13250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOZ74_RS13255	COG0154	amidase activity
FOZ74_RS13260	COG0193	aminoacyl-tRNA hydrolase activity
FOZ74_RS13265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOZ74_RS13270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOZ74_RS13280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOZ74_RS13295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOZ74_RS13305	COG1660	Displays ATPase and GTPase activities
FOZ74_RS13310	COG0497	DNA recombination
FOZ74_RS13315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOZ74_RS13320	COG1420	regulation of RNA biosynthetic process
FOZ74_RS13360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOZ74_RS13365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOZ74_RS13370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOZ74_RS13385	COG1561	YicC-like family, N-terminal region
FOZ74_RS13410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOZ74_RS13420	COG3039	Transposase
FOZ74_RS13450	COG0514	ATP-dependent DNA helicase (RecQ)
FOZ74_RS13460	COG1205	dead DEAH box helicase
FOZ74_RS13460	COG1111	helicase
FOZ74_RS13465	COG0210	DNA helicase
FOZ74_RS13495	COG0194	GDP metabolic process
FOZ74_RS13500	COG1758	RNA polymerase activity
FOZ74_RS13505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOZ74_RS13510	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOZ74_RS13515	COG3028	Belongs to the UPF0307 family
FOZ74_RS13520	COG0312	modulator of DNA gyrase
FOZ74_RS13530	COG0473	3-isopropylmalate dehydrogenase activity
FOZ74_RS13535	COG1610	YqeY-like protein
FOZ74_RS13540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOZ74_RS13545	COG2081	HI0933 family
FOZ74_RS13550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOZ74_RS13555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOZ74_RS13565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOZ74_RS13580	COG0300	oxidoreductase activity
FOZ74_RS13585	COG1414	Transcriptional regulator
FOZ74_RS13590	COG0477	Major facilitator Superfamily
FOZ74_RS13595	COG0625	glutathione transferase activity
FOZ74_RS13610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOZ74_RS13615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOZ74_RS13625	COG0564	pseudouridine synthase activity
FOZ74_RS13630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOZ74_RS13635	COG1187	pseudouridine synthase activity
FOZ74_RS13640	COG0105	UTP biosynthetic process
FOZ74_RS13645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOZ74_RS13665	COG0124	histidyl-tRNA synthetase
FOZ74_RS13675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOZ74_RS13680	COG1160	GTP binding
FOZ74_RS13685	COG1923	regulation of RNA biosynthetic process
FOZ74_RS13690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOZ74_RS13695	COG0330	HflC and HflK could
FOZ74_RS13700	COG0330	HflC and HflK could
FOZ74_RS13710	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOZ74_RS13715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOZ74_RS13720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOZ74_RS13760	COG2022	thiamine diphosphate biosynthetic process
FOZ74_RS13775	COG0351	phosphomethylpyrimidine kinase
FOZ74_RS13785	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOZ74_RS13805	COG0181	hydroxymethylbilane synthase activity
FOZ74_RS13810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOZ74_RS13835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOZ74_RS13840	COG0131	Imidazoleglycerol-phosphate dehydratase
FOZ74_RS13850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOZ74_RS13855	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOZ74_RS13860	COG0107	imidazoleglycerol-phosphate synthase activity
FOZ74_RS13865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOZ74_RS13870	COG0140	phosphoribosyl-ATP diphosphatase activity
FOZ74_RS13890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOZ74_RS13895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOZ74_RS13900	COG0805	protein transport
FOZ74_RS13905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOZ74_RS13910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOZ74_RS13915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOZ74_RS13920	COG1970	mechanosensitive ion channel activity
FOZ74_RS13925	COG0723	plastoquinol--plastocyanin reductase activity
FOZ74_RS13930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOZ74_RS13935	COG2857	Cytochrome c1
FOZ74_RS13940	COG0625	glutathione transferase activity
FOZ74_RS13945	COG2969	positive regulation of protein catabolic process
FOZ74_RS13955	COG2133	pyrroloquinoline quinone binding
FOZ74_RS13965	COG0739	heme binding
FOZ74_RS13970	COG0653	protein targeting
FOZ74_RS13985	COG0494	nUDIX hydrolase
FOZ74_RS13990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOZ74_RS14005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOZ74_RS14010	COG2890	protein-(glutamine-N5) methyltransferase activity
FOZ74_RS14015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOZ74_RS14020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOZ74_RS14030	COG0584	glycerophosphoryl diester phosphodiesterase
FOZ74_RS14035	COG3842	ATPase activity
FOZ74_RS14045	COG3039	Transposase
FOZ74_RS14050	COG0395	ABC-type sugar transport system, permease component
FOZ74_RS14055	COG1175	transmembrane transport
FOZ74_RS14065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOZ74_RS14080	COG2226	methyltransferase
FOZ74_RS14095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOZ74_RS14115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOZ74_RS14130	COG1741	Belongs to the pirin family
FOZ74_RS14140	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOZ74_RS14155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOZ74_RS14170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOZ74_RS14185	COG0688	phosphatidylethanolamine metabolic process
FOZ74_RS14190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOZ74_RS14205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOZ74_RS14215	COG2917	probably involved in intracellular septation
FOZ74_RS14220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOZ74_RS14225	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOZ74_RS14230	COG0318	PFAM AMP-dependent synthetase and ligase
FOZ74_RS14250	COG0411	ABC transporter
FOZ74_RS14260	COG1024	Enoyl-CoA hydratase
FOZ74_RS14260	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOZ74_RS14265	COG0183	Belongs to the thiolase family
FOZ74_RS14300	COG2183	response to ionizing radiation
FOZ74_RS14305	COG0477	Major facilitator Superfamily
FOZ74_RS14310	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOZ74_RS14340	COG2233	PERMEase
FOZ74_RS14345	COG1366	Belongs to the anti-sigma-factor antagonist family
FOZ74_RS14350	COG2172	sigma factor antagonist activity
FOZ74_RS14355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOZ74_RS14370	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOZ74_RS14390	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOZ74_RS14390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOZ74_RS14395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOZ74_RS14400	COG4574	serine-type endopeptidase inhibitor activity
FOZ74_RS14455	COG1846	Transcriptional regulator
FOZ74_RS14475	COG0411	ABC transporter
FOZ74_RS14500	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOZ74_RS14505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOZ74_RS14520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOZ74_RS14565	COG3300	MHYT domain
FOZ74_RS14565	COG5001	Diguanylate cyclase
FOZ74_RS14570	COG1196	nuclear chromosome segregation
FOZ74_RS14580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOZ74_RS14585	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOZ74_RS14615	COG4176	ABC-type proline glycine betaine transport system permease component
FOZ74_RS14620	COG4175	Glycine betaine
FOZ74_RS14625	COG0463	Glycosyl transferase, family 2
FOZ74_RS14635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOZ74_RS14645	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOZ74_RS14670	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOZ74_RS14675	COG0183	Belongs to the thiolase family
FOZ74_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
FOZ74_RS14685	COG0488	(ABC) transporter
FOZ74_RS14695	COG0840	transmembrane signaling receptor activity
FOZ74_RS14700	COG2878	Part of a membrane complex involved in electron transport
FOZ74_RS14715	COG1802	Transcriptional regulator
FOZ74_RS14720	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOZ74_RS14720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOZ74_RS14735	COG1703	isobutyryl-CoA mutase activity
FOZ74_RS14740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOZ74_RS14745	COG4770	biotin carboxylase activity
FOZ74_RS14765	COG1872	DUF167
FOZ74_RS14775	COG0587	DNA-directed DNA polymerase activity
FOZ74_RS14790	COG0579	oxidoreductase
FOZ74_RS14795	COG4566	intracellular signal transduction
FOZ74_RS14815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOZ74_RS14845	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOZ74_RS14880	COG4181	ATPase activity
FOZ74_RS14890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOZ74_RS14905	COG0501	Belongs to the peptidase M48B family
FOZ74_RS14920	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOZ74_RS14925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOZ74_RS14930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOZ74_RS14930	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOZ74_RS14935	COG1741	Belongs to the pirin family
FOZ74_RS14940	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOZ74_RS14945	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOZ74_RS14950	COG0133	tryptophan synthase activity
FOZ74_RS14970	COG0346	lactoylglutathione lyase activity
FOZ74_RS14975	COG0709	Synthesizes selenophosphate from selenide and ATP
FOZ74_RS14980	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOZ74_RS14985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOZ74_RS14990	COG0277	FAD linked oxidase domain protein
FOZ74_RS15000	COG1295	ribonuclease BN
FOZ74_RS15005	COG0277	FAD linked oxidase domain protein
FOZ74_RS15010	COG1304	FMN binding
FOZ74_RS15015	COG2186	Transcriptional regulator
FOZ74_RS15020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOZ74_RS15030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOZ74_RS15155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOZ74_RS15165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOZ74_RS15185	COG4373	Mu-like prophage FluMu protein gp28
FOZ74_RS15190	COG4383	Mu-like prophage protein gp29
FOZ74_RS15205	COG4388	Caudovirus prohead serine protease
FOZ74_RS15215	COG4397	Mu-like prophage major head subunit gpT
FOZ74_RS15225	COG4387	Mu-like prophage protein GP36
FOZ74_RS15285	COG1126	abc transporter atp-binding protein
FOZ74_RS15290	COG0765	amino acid transport
FOZ74_RS15295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOZ74_RS15300	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FOZ74_RS15335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOZ74_RS15340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOZ74_RS15345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOZ74_RS15350	COG0741	lytic transglycosylase activity
FOZ74_RS15365	COG0557	exoribonuclease II activity
FOZ74_RS15380	COG2010	Cytochrome c
FOZ74_RS15380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOZ74_RS15390	COG0779	Required for maturation of 30S ribosomal subunits
FOZ74_RS15395	COG0195	Participates in both transcription termination and antitermination
FOZ74_RS15395	COG2251	uridine kinase activity
FOZ74_RS15400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOZ74_RS15405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOZ74_RS15410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOZ74_RS15415	COG1217	gtp-binding protein TYPA
FOZ74_RS15420	COG1024	Enoyl-CoA hydratase
FOZ74_RS15430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOZ74_RS15435	COG2867	negative regulation of translational initiation
FOZ74_RS15440	COG2914	Belongs to the UPF0125 (RnfH) family
FOZ74_RS15455	COG0519	Catalyzes the synthesis of GMP from XMP
FOZ74_RS15455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOZ74_RS15460	COG0582	viral genome integration into host DNA
FOZ74_RS15505	COG5489	Protein of unknown function (DUF736)
FOZ74_RS15525	COG0631	protein serine/threonine phosphatase activity
FOZ74_RS15535	COG0515	serine threonine protein kinase
FOZ74_RS15535	COG2815	serine threonine protein kinase
FOZ74_RS15540	COG1396	sequence-specific DNA binding
FOZ74_RS15585	COG4959	Type IV secretory pathway protease TraF
FOZ74_RS15600	COG0450	alkyl hydroperoxide reductase
FOZ74_RS15610	COG0640	Transcriptional regulator
FOZ74_RS15620	COG4988	ABC transporter
FOZ74_RS15625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOZ74_RS15635	COG1294	oxidase, subunit
FOZ74_RS15645	COG0583	DNA-binding transcription factor activity
FOZ74_RS15665	COG4962	Type ii secretion system protein e
FOZ74_RS15670	COG3838	Conjugal transfer protein Trbc
FOZ74_RS15680	COG3451	type IV secretory pathway VirB4
FOZ74_RS15695	COG3846	protein secretion by the type IV secretion system
FOZ74_RS15710	COG2948	multi-organism process
FOZ74_RS15720	COG0084	hydrolase, TatD family'
FOZ74_RS15735	COG0300	oxidoreductase activity
FOZ74_RS15750	COG3040	lipid binding
FOZ74_RS15755	COG0415	Belongs to the DNA photolyase family
FOZ74_RS15760	COG0500	methyltransferase
FOZ74_RS15770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOZ74_RS15770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOZ74_RS15780	COG1643	Atp-dependent helicase
FOZ74_RS15790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOZ74_RS15800	COG0563	adenylate kinase activity
FOZ74_RS15805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOZ74_RS15810	COG2835	tetraacyldisaccharide 4'-kinase activity
FOZ74_RS15815	COG1663	tetraacyldisaccharide 4'-kinase activity
FOZ74_RS15820	COG0848	biopolymer transport protein
FOZ74_RS15825	COG0811	peptide transport
FOZ74_RS15830	COG1570	exodeoxyribonuclease VII activity
FOZ74_RS15835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOZ74_RS15845	COG0719	Fe-S assembly protein
FOZ74_RS15850	COG0396	ATPase activity
FOZ74_RS15860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOZ74_RS15865	COG0822	iron-sulfur transferase activity
FOZ74_RS15870	COG2151	metal-sulfur cluster biosynthetic enzyme
FOZ74_RS15885	COG3328	transposase activity
FOZ74_RS15910	COG0114	fumarate hydratase activity
FOZ74_RS15920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOZ74_RS15925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOZ74_RS15935	COG0268	Binds directly to 16S ribosomal RNA
FOZ74_RS15940	COG0728	peptidoglycan biosynthetic process
FOZ74_RS15950	COG0589	response to stress
FOZ74_RS15960	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOZ74_RS15965	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOZ74_RS15975	COG0617	tRNA 3'-terminal CCA addition