locus-tag	class	description
FT644_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FT644_RS00025	COG2205	protein histidine kinase activity
FT644_RS00050	COG1199	ATP-dependent helicase activity
FT644_RS00070	COG2974	May be involved in recombination
FT644_RS00075	COG0183	Belongs to the thiolase family
FT644_RS00080	COG0789	Transcriptional regulator
FT644_RS00090	COG0840	transmembrane signaling receptor activity
FT644_RS00105	COG0445	tRNA wobble uridine modification
FT644_RS00110	COG0357	Ribosomal RNA small subunit methyltransferase G
FT644_RS00120	COG1192	Involved in chromosome partitioning
FT644_RS00130	COG1475	DNA binding
FT644_RS00195	COG0277	FAD linked oxidase domain protein
FT644_RS00205	COG2096	Adenosyltransferase
FT644_RS00210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FT644_RS00215	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FT644_RS00245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FT644_RS00250	COG1846	Transcriptional regulator
FT644_RS00255	COG2176	DNA-directed DNA polymerase activity
FT644_RS00260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FT644_RS00265	COG2175	clavaminate synthase activity
FT644_RS00275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FT644_RS00285	COG0850	regulation of cytokinetic process
FT644_RS00295	COG3706	GGDEF domain
FT644_RS00300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT644_RS00310	COG2233	PERMEase
FT644_RS00320	COG2050	protein possibly involved in aromatic compounds catabolism
FT644_RS00325	COG1960	acyl-CoA dehydrogenase activity
FT644_RS00345	COG2211	Major facilitator Superfamily
FT644_RS00350	COG0745	RESPONSE REGULATOR receiver
FT644_RS00355	COG2205	protein histidine kinase activity
FT644_RS00365	COG3307	-O-antigen
FT644_RS00370	COG0463	Glycosyl transferase, family 2
FT644_RS00400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FT644_RS00405	COG3971	2-oxopent-4-enoate hydratase activity
FT644_RS00410	COG2326	polyphosphate kinase activity
FT644_RS00425	COG0786	glutamate:sodium symporter activity
FT644_RS00435	COG1410	methionine synthase
FT644_RS00435	COG0646	methionine synthase
FT644_RS00445	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS00460	COG0133	tryptophan synthase activity
FT644_RS00495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FT644_RS00505	COG3145	DNA-N1-methyladenine dioxygenase activity
FT644_RS00530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FT644_RS00540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FT644_RS00565	COG0247	lactate metabolic process
FT644_RS00570	COG0277	FAD linked oxidase domain protein
FT644_RS00575	COG0004	ammonium transporteR
FT644_RS00595	COG3119	arylsulfatase activity
FT644_RS00605	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS00610	COG1846	Transcriptional regulator
FT644_RS00615	COG0606	chelatase, subunit chli
FT644_RS00620	COG0583	DNA-binding transcription factor activity
FT644_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS00650	COG0411	ABC transporter
FT644_RS00660	COG0683	leucine binding
FT644_RS00675	COG0427	acetyl-CoA hydrolase
FT644_RS00680	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS00695	COG1380	Effector of murein hydrolase LrgA
FT644_RS00700	COG0583	DNA-binding transcription factor activity
FT644_RS00720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT644_RS00725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FT644_RS00730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FT644_RS00735	COG1280	lysine exporter protein (LysE YggA)
FT644_RS00750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FT644_RS00770	COG2239	Acts as a magnesium transporter
FT644_RS00780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT644_RS00785	COG0584	glycerophosphoryl diester phosphodiesterase
FT644_RS00800	COG3300	MHYT domain
FT644_RS00800	COG5001	Diguanylate cyclase
FT644_RS00805	COG1297	OPT oligopeptide transporter protein
FT644_RS00810	COG1073	alpha beta
FT644_RS00830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FT644_RS00835	COG0154	amidase activity
FT644_RS00840	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FT644_RS00845	COG1077	Cell shape determining protein MreB Mrl
FT644_RS00850	COG1792	Involved in formation and maintenance of cell shape
FT644_RS00865	COG0768	penicillin binding
FT644_RS00880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FT644_RS00885	COG1127	ABC transporter
FT644_RS00910	COG2095	MarC family integral membrane protein
FT644_RS00915	COG0412	Dienelactone hydrolase
FT644_RS00920	COG0598	Magnesium transport protein CorA
FT644_RS00945	COG2945	thiolester hydrolase activity
FT644_RS00950	COG1686	Belongs to the peptidase S11 family
FT644_RS00955	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FT644_RS00960	COG0049	tRNA binding
FT644_RS00965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FT644_RS00970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FT644_RS00975	COG0051	transcription antitermination factor activity, RNA binding
FT644_RS00980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FT644_RS00985	COG0088	Forms part of the polypeptide exit tunnel
FT644_RS00990	COG0089	rRNA binding
FT644_RS00995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FT644_RS01000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FT644_RS01005	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FT644_RS01010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FT644_RS01015	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FT644_RS01020	COG0255	Belongs to the universal ribosomal protein uL29 family
FT644_RS01025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FT644_RS01030	COG0678	peroxiredoxin activity
FT644_RS01045	COG3909	cytochrome
FT644_RS01050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FT644_RS01065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FT644_RS01070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FT644_RS01075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FT644_RS01080	COG0321	lipoyl(octanoyl) transferase activity
FT644_RS01085	COG2921	Belongs to the UPF0250 family
FT644_RS01095	COG0356	it plays a direct role in the translocation of protons across the membrane
FT644_RS01105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FT644_RS01110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FT644_RS01115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FT644_RS01120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FT644_RS01125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FT644_RS01130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FT644_RS01140	COG1278	Cold shock
FT644_RS01165	COG0429	hydrolase of the alpha beta-hydrolase fold
FT644_RS01180	COG1538	Outer membrane efflux protein
FT644_RS01220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FT644_RS01230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FT644_RS01240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FT644_RS01245	COG0081	regulation of translation
FT644_RS01250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FT644_RS01255	COG0222	ribosome binding
FT644_RS01260	COG0085	RNA polymerase activity
FT644_RS01265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FT644_RS01270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FT644_RS01270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT644_RS01280	COG5000	phosphorelay sensor kinase activity
FT644_RS01285	COG2204	response regulator
FT644_RS01340	COG0582	viral genome integration into host DNA
FT644_RS01345	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FT644_RS01350	COG1074	ATP-dependent DNA helicase activity
FT644_RS01355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FT644_RS01365	COG0625	glutathione transferase activity
FT644_RS01395	COG2072	flavoprotein involved in K transport
FT644_RS01400	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS01445	COG0343	queuine tRNA-ribosyltransferase activity
FT644_RS01470	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS01475	COG1024	Enoyl-CoA hydratase
FT644_RS01480	COG1960	acyl-CoA dehydrogenase activity
FT644_RS01515	COG0210	DNA helicase
FT644_RS01540	COG0679	Auxin Efflux Carrier
FT644_RS01555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FT644_RS01560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FT644_RS01580	COG0534	Mate efflux family protein
FT644_RS01590	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS01605	COG1840	ABC-type Fe3 transport system, periplasmic component
FT644_RS01610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FT644_RS01615	COG3842	ATPase activity
FT644_RS01620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FT644_RS01635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT644_RS01640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT644_RS01660	COG1815	bacterial-type flagellum-dependent cell motility
FT644_RS01665	COG1558	bacterial-type flagellum-dependent cell motility
FT644_RS01670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FT644_RS01675	COG1749	Flagellar hook protein flgE
FT644_RS01680	COG4787	bacterial-type flagellum-dependent cell motility
FT644_RS01685	COG4786	Flagellar basal body rod
FT644_RS01690	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FT644_RS01695	COG1706	bacterial-type flagellum-dependent cell motility
FT644_RS01700	COG1705	Flagellar rod assembly protein muramidase FlgJ
FT644_RS01700	COG3951	Flagellar rod assembly protein muramidase FlgJ
FT644_RS01705	COG1256	bacterial-type flagellum assembly
FT644_RS01710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FT644_RS01725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FT644_RS01740	COG1191	sigma factor activity
FT644_RS01755	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FT644_RS01760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FT644_RS01765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FT644_RS01780	COG0745	RESPONSE REGULATOR receiver
FT644_RS01785	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FT644_RS01790	COG1677	Flagellar hook-basal body complex protein FliE
FT644_RS01795	COG1766	The M ring may be actively involved in energy transduction
FT644_RS01800	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FT644_RS01810	COG1157	protein secretion by the type III secretion system
FT644_RS01835	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FT644_RS01840	COG3190	flagellar
FT644_RS01850	COG1987	bacterial-type flagellum assembly
FT644_RS01880	COG0643	Histidine kinase
FT644_RS01880	COG2198	Histidine kinase
FT644_RS01885	COG0835	chemotaxis
FT644_RS01890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FT644_RS01900	COG2201	protein-glutamate methylesterase activity
FT644_RS01990	COG0789	Transcriptional regulator
FT644_RS02000	COG1960	acyl-CoA dehydrogenase activity
FT644_RS02005	COG0288	reversible hydration of carbon dioxide
FT644_RS02010	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FT644_RS02015	COG0183	Belongs to the thiolase family
FT644_RS02035	COG1960	acyl-CoA dehydrogenase activity
FT644_RS02045	COG3012	SEC-C Motif Domain Protein
FT644_RS02050	COG0784	Response regulator, receiver
FT644_RS02050	COG2198	Histidine kinase
FT644_RS02050	COG5002	protein histidine kinase activity
FT644_RS02055	COG2197	response regulator
FT644_RS02070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FT644_RS02085	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS02090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FT644_RS02095	COG1024	Enoyl-CoA hydratase
FT644_RS02110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT644_RS02125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FT644_RS02140	COG1902	pentaerythritol trinitrate reductase activity
FT644_RS02150	COG3162	membrane
FT644_RS02165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FT644_RS02170	COG0477	Major facilitator Superfamily
FT644_RS02175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FT644_RS02180	COG1414	Transcriptional regulator
FT644_RS02185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FT644_RS02200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FT644_RS02210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FT644_RS02215	COG2814	Major facilitator Superfamily
FT644_RS02225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FT644_RS02230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FT644_RS02235	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FT644_RS02245	COG2205	protein histidine kinase activity
FT644_RS02250	COG0745	RESPONSE REGULATOR receiver
FT644_RS02255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FT644_RS02265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FT644_RS02275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FT644_RS02280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FT644_RS02285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FT644_RS02290	COG0316	Belongs to the HesB IscA family
FT644_RS02295	COG2814	Major facilitator Superfamily
FT644_RS02305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FT644_RS02310	COG2252	PERMEase
FT644_RS02315	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FT644_RS02330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FT644_RS02335	COG0583	DNA-binding transcription factor activity
FT644_RS02340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FT644_RS02350	COG3706	GGDEF domain
FT644_RS02355	COG1522	sequence-specific DNA binding
FT644_RS02360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FT644_RS02385	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FT644_RS02390	COG1984	allophanate hydrolase subunit 2
FT644_RS02395	COG4770	biotin carboxylase activity
FT644_RS02415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FT644_RS02425	COG4585	Histidine kinase
FT644_RS02430	COG0307	riboflavin synthase, alpha
FT644_RS02450	COG0443	Heat shock 70 kDa protein
FT644_RS02465	COG0387	Pfam Sodium calcium exchanger
FT644_RS02470	COG0443	Heat shock 70 kDa protein
FT644_RS02495	COG4772	TonB-dependent receptor
FT644_RS02520	COG1120	ATPase activity
FT644_RS02540	COG0583	DNA-binding transcription factor activity
FT644_RS02550	COG3045	CreA protein
FT644_RS02555	COG2814	Major facilitator Superfamily
FT644_RS02560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FT644_RS02560	COG0189	ligase activity
FT644_RS02570	COG1132	(ABC) transporter
FT644_RS02600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FT644_RS02675	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FT644_RS02680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FT644_RS02690	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FT644_RS02705	COG0459	protein refolding
FT644_RS02710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FT644_RS02715	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
FT644_RS02770	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS02780	COG3039	Transposase
FT644_RS02800	COG1056	cytidyltransferase-related domain
FT644_RS02800	COG1051	belongs to the nudix hydrolase family
FT644_RS02805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FT644_RS02805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FT644_RS02810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FT644_RS02830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FT644_RS02840	COG1560	Kdo2-lipid A biosynthetic process
FT644_RS02850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FT644_RS02860	COG1333	cytochrome c biogenesis protein
FT644_RS02870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FT644_RS02875	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FT644_RS02890	COG1965	Belongs to the frataxin family
FT644_RS02900	COG0443	Heat shock 70 kDa protein
FT644_RS02925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FT644_RS02935	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FT644_RS02950	COG0166	Belongs to the GPI family
FT644_RS02955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FT644_RS02965	COG0183	Belongs to the thiolase family
FT644_RS02975	COG0069	glutamate synthase activity
FT644_RS02975	COG0067	glutamate synthase
FT644_RS02975	COG0070	glutamate synthase
FT644_RS02990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT644_RS02995	COG0765	amino acid transport
FT644_RS03005	COG1127	ABC transporter
FT644_RS03010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FT644_RS03015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FT644_RS03035	COG1131	(ABC) transporter
FT644_RS03040	COG0842	Transport permease protein
FT644_RS03045	COG0271	Belongs to the BolA IbaG family
FT644_RS03050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FT644_RS03055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FT644_RS03090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FT644_RS03095	COG0131	Imidazoleglycerol-phosphate dehydratase
FT644_RS03105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FT644_RS03120	COG0297	glycogen (starch) synthase activity
FT644_RS03150	COG0107	imidazoleglycerol-phosphate synthase activity
FT644_RS03155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FT644_RS03160	COG0140	phosphoribosyl-ATP diphosphatase activity
FT644_RS03175	COG0537	adenosine 5'-monophosphoramidase activity
FT644_RS03180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FT644_RS03185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FT644_RS03190	COG0805	protein transport
FT644_RS03195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT644_RS03205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FT644_RS03210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FT644_RS03215	COG1970	mechanosensitive ion channel activity
FT644_RS03220	COG0723	plastoquinol--plastocyanin reductase activity
FT644_RS03225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FT644_RS03230	COG2857	Cytochrome c1
FT644_RS03235	COG0625	glutathione transferase activity
FT644_RS03240	COG2969	positive regulation of protein catabolic process
FT644_RS03255	COG0653	protein targeting
FT644_RS03275	COG0494	nUDIX hydrolase
FT644_RS03280	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FT644_RS03285	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FT644_RS03290	COG0237	dephospho-CoA kinase activity
FT644_RS03295	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FT644_RS03320	COG3550	peptidyl-serine autophosphorylation
FT644_RS03330	COG2129	metallophosphoesterase
FT644_RS03360	COG0443	Heat shock 70 kDa protein
FT644_RS03445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FT644_RS03455	COG1074	ATP-dependent DNA helicase activity
FT644_RS03460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FT644_RS03540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FT644_RS03550	COG1192	Involved in chromosome partitioning
FT644_RS03575	COG0142	geranyltranstransferase activity
FT644_RS03580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FT644_RS03585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FT644_RS03590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FT644_RS03595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FT644_RS03600	COG0494	nUDIX hydrolase
FT644_RS03605	COG0442	prolyl-tRNA aminoacylation
FT644_RS03610	COG0741	lytic transglycosylase activity
FT644_RS03620	COG1253	flavin adenine dinucleotide binding
FT644_RS03630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FT644_RS03635	COG2890	protein-(glutamine-N5) methyltransferase activity
FT644_RS03640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FT644_RS03645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FT644_RS03660	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS03675	COG0584	glycerophosphoryl diester phosphodiesterase
FT644_RS03680	COG3842	ATPase activity
FT644_RS03685	COG0395	ABC-type sugar transport system, permease component
FT644_RS03690	COG1175	transmembrane transport
FT644_RS03695	COG1653	transport
FT644_RS03715	COG2226	methyltransferase
FT644_RS03730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FT644_RS03750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FT644_RS03770	COG0302	gtp cyclohydrolase
FT644_RS03785	COG0747	negative chemotaxis
FT644_RS03790	COG4608	Belongs to the ABC transporter superfamily
FT644_RS03800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FT644_RS03815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FT644_RS03820	COG0193	aminoacyl-tRNA hydrolase activity
FT644_RS03825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FT644_RS03830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FT644_RS03840	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FT644_RS03845	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FT644_RS03855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FT644_RS03875	COG4452	Inner membrane protein CreD
FT644_RS03880	COG2205	protein histidine kinase activity
FT644_RS03885	COG0745	RESPONSE REGULATOR receiver
FT644_RS03890	COG1660	Displays ATPase and GTPase activities
FT644_RS03895	COG0497	DNA recombination
FT644_RS03900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FT644_RS03905	COG1420	regulation of RNA biosynthetic process
FT644_RS03930	COG0745	RESPONSE REGULATOR receiver
FT644_RS03935	COG0180	Tryptophanyl-tRNA synthetase
FT644_RS03940	COG1994	Peptidase M50
FT644_RS03945	COG0840	transmembrane signaling receptor activity
FT644_RS03955	COG0009	L-threonylcarbamoyladenylate synthase
FT644_RS03960	COG0613	PHP domain protein
FT644_RS03965	COG0840	transmembrane signaling receptor activity
FT644_RS03970	COG0840	transmembrane signaling receptor activity
FT644_RS03990	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS04000	COG4591	ABC-type transport system involved in lipoprotein release permease component
FT644_RS04005	COG1136	(ABC) transporter
FT644_RS04015	COG0084	hydrolase, TatD family'
FT644_RS04030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FT644_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS04055	COG0697	spore germination
FT644_RS04065	COG1283	sodium-dependent phosphate transmembrane transporter activity
FT644_RS04075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FT644_RS04085	COG0196	riboflavin kinase activity
FT644_RS04095	COG3781	membrane
FT644_RS04100	COG0590	tRNA wobble adenosine to inosine editing
FT644_RS04105	COG1960	acyl-CoA dehydrogenase activity
FT644_RS04110	COG1960	acyl-CoA dehydrogenase activity
FT644_RS04115	COG3132	Protein of unknown function, DUF480
FT644_RS04120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FT644_RS04135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FT644_RS04135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT644_RS04145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FT644_RS04150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FT644_RS04155	COG0492	ferredoxin-NADP+ reductase activity
FT644_RS04160	COG1674	ftsk spoiiie
FT644_RS04165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FT644_RS04175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FT644_RS04180	COG0559	Belongs to the binding-protein-dependent transport system permease family
FT644_RS04200	COG3039	Transposase
FT644_RS04205	COG1392	Phosphate transport regulator
FT644_RS04210	COG0306	phosphate transporter
FT644_RS04225	COG0228	four-way junction DNA binding
FT644_RS04230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FT644_RS04235	COG0336	Belongs to the RNA methyltransferase TrmD family
FT644_RS04240	COG0335	large ribosomal subunit rRNA binding
FT644_RS04245	COG0494	nUDIX hydrolase
FT644_RS04250	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FT644_RS04255	COG1162	GTPase activity
FT644_RS04260	COG2154	pterin-4-alpha-carbinolamine dehydratase
FT644_RS04265	COG0501	Belongs to the peptidase M48B family
FT644_RS04270	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FT644_RS04275	COG0513	Belongs to the DEAD box helicase family
FT644_RS04280	COG2814	Major facilitator Superfamily
FT644_RS04305	COG2084	Dehydrogenase
FT644_RS04310	COG0516	GMP reductase activity
FT644_RS04330	COG2814	Major facilitator Superfamily
FT644_RS04335	COG0210	DNA helicase
FT644_RS04340	COG1063	alcohol dehydrogenase
FT644_RS04355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FT644_RS04380	COG0412	Dienelactone hydrolase
FT644_RS04395	COG3275	phosphorelay sensor kinase activity
FT644_RS04400	COG0697	spore germination
FT644_RS04405	COG0165	Argininosuccinate lyase
FT644_RS04440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FT644_RS04450	COG1304	FMN binding
FT644_RS04455	COG2186	Transcriptional regulator
FT644_RS04460	COG1620	l-lactate permease
FT644_RS04470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FT644_RS04485	COG0833	amino acid
FT644_RS04490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FT644_RS04495	COG0840	transmembrane signaling receptor activity
FT644_RS04510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FT644_RS04510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FT644_RS04520	COG3022	response to hydroperoxide
FT644_RS04525	COG1530	ribonuclease E activity
FT644_RS04530	COG0564	pseudouridine synthase activity
FT644_RS04545	COG0616	signal peptide processing
FT644_RS04545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FT644_RS04550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FT644_RS04555	COG0424	maF-like protein
FT644_RS04560	COG1399	metal-binding, possibly nucleic acid-binding protein
FT644_RS04565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FT644_RS04570	COG0416	fatty acid biosynthetic process
FT644_RS04575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FT644_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS04590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FT644_RS04595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FT644_RS04615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT644_RS04620	COG0481	GTPase activity
FT644_RS04625	COG0681	Belongs to the peptidase S26 family
FT644_RS04635	COG0571	ribonuclease III activity
FT644_RS04640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FT644_RS04645	COG1381	Involved in DNA repair and RecF pathway recombination
FT644_RS04650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FT644_RS04655	COG0736	holo-[acyl-carrier-protein] synthase activity
FT644_RS04660	COG1472	Belongs to the glycosyl hydrolase 3 family
FT644_RS04680	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FT644_RS04690	COG2203	Gaf domain
FT644_RS04690	COG4251	negative regulation of phosphorylation
FT644_RS04690	COG5001	Diguanylate cyclase
FT644_RS04690	COG3706	GGDEF domain
FT644_RS04700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FT644_RS04710	COG0762	integral membrane protein
FT644_RS04720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FT644_RS04725	COG0159	tryptophan synthase activity
FT644_RS04730	COG0133	tryptophan synthase activity
FT644_RS04735	COG0135	phosphoribosylanthranilate isomerase activity
FT644_RS04740	COG0101	tRNA pseudouridine synthase activity
FT644_RS04755	COG0473	3-isopropylmalate dehydrogenase activity
FT644_RS04760	COG0066	3-isopropylmalate dehydratase activity
FT644_RS04765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FT644_RS04780	COG0484	heat shock protein binding
FT644_RS04785	COG0443	Heat shock 70 kDa protein
FT644_RS04790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FT644_RS04795	COG0360	Binds together with S18 to 16S ribosomal RNA
FT644_RS04805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FT644_RS04810	COG0359	binds to the 23S rRNA
FT644_RS04815	COG0305	Participates in initiation and elongation during chromosome replication
FT644_RS04825	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FT644_RS04830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FT644_RS04840	COG0436	Aminotransferase
FT644_RS04855	COG1763	Mo-molybdopterin cofactor biosynthetic process
FT644_RS04865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FT644_RS04890	COG0314	molybdopterin synthase activity
FT644_RS04895	COG0542	response to heat
FT644_RS04930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FT644_RS04935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FT644_RS04935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FT644_RS04980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FT644_RS04985	COG1185	polyribonucleotide nucleotidyltransferase activity
FT644_RS04995	COG0149	triose-phosphate isomerase activity
FT644_RS05010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT644_RS05015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT644_RS05020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT644_RS05025	COG0649	NAD binding
FT644_RS05040	COG1034	ATP synthesis coupled electron transport
FT644_RS05045	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FT644_RS05050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FT644_RS05060	COG0713	ATP synthesis coupled electron transport
FT644_RS05075	COG1007	ATP synthesis coupled electron transport
FT644_RS05095	COG0410	ABC transporter
FT644_RS05105	COG0559	Belongs to the binding-protein-dependent transport system permease family
FT644_RS05135	COG4206	TonB-dependent receptor
FT644_RS05140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FT644_RS05155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FT644_RS05160	COG2814	Major facilitator Superfamily
FT644_RS05195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FT644_RS05200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FT644_RS05210	COG0586	Pfam SNARE associated Golgi protein
FT644_RS05220	COG0860	N-Acetylmuramoyl-L-alanine amidase
FT644_RS05230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FT644_RS05240	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS05245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FT644_RS05250	COG4974	Belongs to the 'phage' integrase family
FT644_RS05265	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FT644_RS05270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FT644_RS05275	COG2833	Protein of unknown function (DUF455)
FT644_RS05285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FT644_RS05300	COG0148	phosphopyruvate hydratase activity
FT644_RS05310	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FT644_RS05315	COG0504	CTP synthase activity
FT644_RS05320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FT644_RS05345	COG1047	Peptidyl-prolyl cis-trans
FT644_RS05360	COG1012	belongs to the aldehyde dehydrogenase family
FT644_RS05370	COG0411	ABC transporter
FT644_RS05410	COG1012	belongs to the aldehyde dehydrogenase family
FT644_RS05420	COG2850	peptidyl-arginine hydroxylation
FT644_RS05430	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FT644_RS05435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FT644_RS05455	COG0187	DNA topoisomerase II activity
FT644_RS05460	COG0739	heme binding
FT644_RS05460	COG1196	nuclear chromosome segregation
FT644_RS05460	COG0741	lytic transglycosylase activity
FT644_RS05485	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FT644_RS05500	COG2308	Evidence 4 Homologs of previously reported genes of
FT644_RS05545	COG4558	Periplasmic binding protein
FT644_RS05550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FT644_RS05555	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FT644_RS05560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FT644_RS05575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FT644_RS05610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FT644_RS05615	COG0358	DNA primase activity
FT644_RS05620	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS05625	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS05630	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT644_RS05640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FT644_RS05650	COG0215	cysteine-tRNA ligase activity
FT644_RS05685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FT644_RS05715	COG0037	tRNA processing
FT644_RS05765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FT644_RS05770	COG0642	Histidine kinase
FT644_RS05780	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS05800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT644_RS05830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FT644_RS05835	COG1011	Hydrolase
FT644_RS05855	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FT644_RS05875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FT644_RS05885	COG0582	viral genome integration into host DNA
FT644_RS05960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FT644_RS06095	COG4695	Portal protein
FT644_RS06100	COG0544	peptidyl-prolyl cis-trans isomerase activity
FT644_RS06105	COG0740	serine-type endopeptidase activity
FT644_RS06110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FT644_RS06115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FT644_RS06150	COG3293	Transposase
FT644_RS06170	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FT644_RS06175	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FT644_RS06210	COG4628	conserved protein (DUF2132)
FT644_RS06220	COG5001	Diguanylate cyclase
FT644_RS06220	COG5002	protein histidine kinase activity
FT644_RS06225	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FT644_RS06245	COG2610	gluconate transmembrane transporter activity
FT644_RS06250	COG1929	Belongs to the glycerate kinase type-1 family
FT644_RS06260	COG0513	Belongs to the DEAD box helicase family
FT644_RS06265	COG0372	Belongs to the citrate synthase family
FT644_RS06270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FT644_RS06275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FT644_RS06280	COG1053	succinate dehydrogenase
FT644_RS06285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FT644_RS06295	COG2188	Transcriptional regulator
FT644_RS06300	COG0039	L-malate dehydrogenase activity
FT644_RS06305	COG4106	trans-aconitate 2-methyltransferase activity
FT644_RS06325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FT644_RS06395	COG0848	biopolymer transport protein
FT644_RS06405	COG0824	Thioesterase
FT644_RS06410	COG0436	Aminotransferase
FT644_RS06415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FT644_RS06420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FT644_RS06445	COG4774	siderophore transport
FT644_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS06465	COG2918	glutathione biosynthetic process
FT644_RS06470	COG0840	transmembrane signaling receptor activity
FT644_RS06495	COG1473	amidohydrolase
FT644_RS06505	COG0564	pseudouridine synthase activity
FT644_RS06510	COG2962	Rard protein
FT644_RS06550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT644_RS06560	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FT644_RS06585	COG0024	Methionine aminopeptidase
FT644_RS06595	COG1252	NADH dehydrogenase
FT644_RS06600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FT644_RS06605	COG0604	alcohol dehydrogenase
FT644_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS06605	COG3321	synthase
FT644_RS06610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FT644_RS06615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FT644_RS06630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FT644_RS06635	COG1187	pseudouridine synthase activity
FT644_RS06640	COG0105	UTP biosynthetic process
FT644_RS06645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FT644_RS06665	COG0124	histidyl-tRNA synthetase
FT644_RS06675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT644_RS06680	COG1160	GTP binding
FT644_RS06685	COG1923	regulation of RNA biosynthetic process
FT644_RS06690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FT644_RS06695	COG0330	HflC and HflK could
FT644_RS06700	COG0330	HflC and HflK could
FT644_RS06710	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FT644_RS06715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FT644_RS06720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FT644_RS06755	COG3852	Histidine kinase
FT644_RS06770	COG0708	Exodeoxyribonuclease III
FT644_RS06775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FT644_RS06785	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FT644_RS06815	COG0277	FAD linked oxidase domain protein
FT644_RS06830	COG1295	ribonuclease BN
FT644_RS06835	COG1022	Amp-dependent synthetase and ligase
FT644_RS06855	COG2267	carboxylic ester hydrolase activity
FT644_RS06860	COG0456	acetyltransferase
FT644_RS06875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FT644_RS06880	COG0737	Belongs to the 5'-nucleotidase family
FT644_RS06885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FT644_RS06890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FT644_RS06895	COG0741	lytic transglycosylase activity
FT644_RS06940	COG0557	exoribonuclease II activity
FT644_RS06945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FT644_RS06945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FT644_RS06955	COG0052	Belongs to the universal ribosomal protein uS2 family
FT644_RS06960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FT644_RS06965	COG0528	UMP kinase activity
FT644_RS06970	COG0233	cytoplasmic translational termination
FT644_RS06985	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FT644_RS06990	COG0750	zinc metalloprotease
FT644_RS07005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT644_RS07010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT644_RS07015	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT644_RS07020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FT644_RS07025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FT644_RS07030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FT644_RS07035	COG0505	Belongs to the CarA family
FT644_RS07040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FT644_RS07045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT644_RS07065	COG1534	Rna-binding protein
FT644_RS07070	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FT644_RS07075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FT644_RS07085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FT644_RS07115	COG0248	Ppx GppA phosphatase
FT644_RS07120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FT644_RS07125	COG0573	inorganic phosphate transmembrane transporter activity
FT644_RS07130	COG0581	inorganic phosphate transmembrane transporter activity
FT644_RS07135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FT644_RS07140	COG0704	Plays a role in the regulation of phosphate uptake
FT644_RS07155	COG0534	Mate efflux family protein
FT644_RS07165	COG0254	rRNA binding
FT644_RS07170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FT644_RS07215	COG0242	peptide deformylase activity
FT644_RS07220	COG2233	PERMEase
FT644_RS07225	COG0492	ferredoxin-NADP+ reductase activity
FT644_RS07230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FT644_RS07235	COG2895	sulfate adenylyltransferase (ATP) activity
FT644_RS07240	COG0175	sulfate reduction
FT644_RS07260	COG1253	flavin adenine dinucleotide binding
FT644_RS07265	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FT644_RS07265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FT644_RS07270	COG2860	membrane
FT644_RS07275	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FT644_RS07280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FT644_RS07290	COG0506	proline dehydrogenase activity
FT644_RS07290	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FT644_RS07290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FT644_RS07330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FT644_RS07345	COG0670	Belongs to the BI1 family
FT644_RS07350	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FT644_RS07385	COG3128	pkhd-type hydroxylase
FT644_RS07390	COG4774	siderophore transport
FT644_RS07410	COG1477	protein flavinylation
FT644_RS07425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FT644_RS07435	COG2224	Isocitrate lyase
FT644_RS07440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FT644_RS07445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FT644_RS07450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FT644_RS07455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FT644_RS07460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FT644_RS07470	COG0776	regulation of translation
FT644_RS07485	COG2267	carboxylic ester hydrolase activity
FT644_RS07490	COG0667	Aldo Keto reductase
FT644_RS07500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FT644_RS07515	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FT644_RS07530	COG3577	Aspartyl protease
FT644_RS07535	COG1666	GTP binding
FT644_RS07540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FT644_RS07550	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FT644_RS07585	COG1982	Orn Lys Arg decarboxylase major
FT644_RS07595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FT644_RS07600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FT644_RS07605	COG1793	dna ligase
FT644_RS07610	COG2032	superoxide dismutase activity
FT644_RS07625	COG4174	ABC transporter (Permease)
FT644_RS07630	COG4239	(ABC) transporter, permease
FT644_RS07635	COG4172	Belongs to the ABC transporter superfamily
FT644_RS07655	COG0779	Required for maturation of 30S ribosomal subunits
FT644_RS07660	COG0195	Participates in both transcription termination and antitermination
FT644_RS07665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FT644_RS07670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FT644_RS07675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FT644_RS07690	COG4215	(ABC) transporter
FT644_RS07720	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS07725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FT644_RS07740	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS07745	COG0589	response to stress
FT644_RS07750	COG2217	Heavy metal translocating P-type atpase
FT644_RS07760	COG3278	Belongs to the heme-copper respiratory oxidase family
FT644_RS07780	COG0348	domain, Protein
FT644_RS07795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT644_RS07800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FT644_RS07840	COG1797	cobyrinic acid a,c-diamide synthase activity
FT644_RS07850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FT644_RS07855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FT644_RS07860	COG1120	ATPase activity
FT644_RS07865	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FT644_RS07870	COG0778	Nitroreductase
FT644_RS07875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FT644_RS07895	COG1492	cobalamin metabolic process
FT644_RS07905	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FT644_RS07910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FT644_RS07920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT644_RS07955	COG1522	sequence-specific DNA binding
FT644_RS07960	COG5006	permease, DMT superfamily
FT644_RS07965	COG2766	serine protein kinase
FT644_RS07970	COG2718	Belongs to the UPF0229 family
FT644_RS07975	COG2719	SpoVR family
FT644_RS07980	COG1464	Belongs to the NlpA lipoprotein family
FT644_RS07985	COG3530	Putative quorum-sensing-regulated virulence factor
FT644_RS07995	COG0431	NADPH-dependent FMN reductase
FT644_RS08000	COG0560	Phosphoserine phosphatase
FT644_RS08010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FT644_RS08015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FT644_RS08015	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FT644_RS08020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FT644_RS08020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FT644_RS08025	COG2205	protein histidine kinase activity
FT644_RS08030	COG0745	RESPONSE REGULATOR receiver
FT644_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS08050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FT644_RS08070	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS08115	COG2267	carboxylic ester hydrolase activity
FT644_RS08190	COG0753	catalase activity
FT644_RS08195	COG1960	acyl-CoA dehydrogenase activity
FT644_RS08205	COG0494	nUDIX hydrolase
FT644_RS08230	COG4654	Cytochrome c, class I
FT644_RS08235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FT644_RS08240	COG4654	Cytochrome c, class I
FT644_RS08265	COG0737	Belongs to the 5'-nucleotidase family
FT644_RS08270	COG2391	methyltransferase activity
FT644_RS08275	COG0436	Aminotransferase
FT644_RS08280	COG0583	DNA-binding transcription factor activity
FT644_RS08300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FT644_RS08315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FT644_RS08330	COG0640	Transcriptional regulator
FT644_RS08360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FT644_RS08365	COG2011	ABC-type metal ion transport system permease component
FT644_RS08375	COG1464	Belongs to the NlpA lipoprotein family
FT644_RS08390	COG0183	Belongs to the thiolase family
FT644_RS08395	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS08400	COG1268	BioY protein
FT644_RS08410	COG1122	ATPase activity
FT644_RS08425	COG1116	anion transmembrane transporter activity
FT644_RS08430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FT644_RS08440	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS08450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FT644_RS08455	COG0583	DNA-binding transcription factor activity
FT644_RS08465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FT644_RS08470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FT644_RS08475	COG4208	sulfate ABC transporter
FT644_RS08480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FT644_RS08485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FT644_RS08520	COG0038	chloride channel
FT644_RS08525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FT644_RS08540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FT644_RS08540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FT644_RS08550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT644_RS08565	COG2814	Major facilitator Superfamily
FT644_RS08590	COG1643	Atp-dependent helicase
FT644_RS08595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FT644_RS08610	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS08620	COG3276	selenocysteine insertion sequence binding
FT644_RS08625	COG1921	L-seryl-tRNASec selenium transferase activity
FT644_RS08635	COG2864	formate dehydrogenase
FT644_RS08640	COG0437	4 iron, 4 sulfur cluster binding
FT644_RS08655	COG0567	Dehydrogenase, E1 component
FT644_RS08660	COG0508	dehydrogenase complex catalyzes the overall conversion of
FT644_RS08665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FT644_RS08670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FT644_RS08685	COG1199	ATP-dependent helicase activity
FT644_RS08700	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FT644_RS08705	COG0542	response to heat
FT644_RS08710	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FT644_RS08725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FT644_RS08730	COG1845	cytochrome c oxidase, subunit III
FT644_RS08735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FT644_RS08740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FT644_RS08745	COG0477	Major facilitator Superfamily
FT644_RS08755	COG0583	DNA-binding transcription factor activity
FT644_RS08765	COG1414	Transcriptional regulator
FT644_RS08770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FT644_RS08795	COG0642	Histidine kinase
FT644_RS08805	COG3258	Cytochrome c
FT644_RS08810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FT644_RS08815	COG3384	dioxygenase
FT644_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS08840	COG0410	ABC transporter
FT644_RS08855	COG0559	Belongs to the binding-protein-dependent transport system permease family
FT644_RS08865	COG0564	pseudouridine synthase activity
FT644_RS08875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FT644_RS08875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FT644_RS08885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FT644_RS08900	COG2814	Major facilitator Superfamily
FT644_RS08905	COG1566	PFAM secretion protein HlyD family protein
FT644_RS08910	COG1538	Outer membrane efflux protein
FT644_RS08925	COG3639	organic phosphonate transmembrane transporter activity
FT644_RS08935	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FT644_RS08945	COG3039	Transposase
FT644_RS08955	COG3316	Transposase and inactivated derivatives
FT644_RS08965	COG3173	Aminoglycoside phosphotransferase
FT644_RS08970	COG3316	Transposase and inactivated derivatives
FT644_RS09020	COG0583	DNA-binding transcription factor activity
FT644_RS09065	COG3316	Transposase and inactivated derivatives
FT644_RS09095	COG3039	Transposase
FT644_RS09115	COG0402	S-adenosylhomocysteine deaminase activity
FT644_RS09135	COG0519	Catalyzes the synthesis of GMP from XMP
FT644_RS09135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FT644_RS09170	COG2867	negative regulation of translational initiation
FT644_RS09175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FT644_RS09185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FT644_RS09195	COG3706	GGDEF domain
FT644_RS09200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FT644_RS09205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT644_RS09215	COG0583	DNA-binding transcription factor activity
FT644_RS09220	COG1741	Belongs to the pirin family
FT644_RS09240	COG0455	bacterial-type flagellum organization
FT644_RS09245	COG3706	GGDEF domain
FT644_RS09250	COG0659	secondary active sulfate transmembrane transporter activity
FT644_RS09265	COG0833	amino acid
FT644_RS09270	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FT644_RS09275	COG4120	Belongs to the binding-protein-dependent transport system permease family
FT644_RS09300	COG1739	Uncharacterized protein family UPF0029
FT644_RS09305	COG2197	response regulator
FT644_RS09345	COG0625	glutathione transferase activity
FT644_RS09360	COG3243	poly(R)-hydroxyalkanoic acid synthase
FT644_RS09365	COG0183	Belongs to the thiolase family
FT644_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS09385	COG2271	Major facilitator Superfamily
FT644_RS09400	COG0531	amino acid
FT644_RS09420	COG0791	NLP P60 protein
FT644_RS09430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT644_RS09455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FT644_RS09470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FT644_RS09490	COG0259	pyridoxamine-phosphate oxidase activity
FT644_RS09495	COG0583	DNA-binding transcription factor activity
FT644_RS09500	COG2032	superoxide dismutase activity
FT644_RS09520	COG0346	lactoylglutathione lyase activity
FT644_RS09565	COG2199	diguanylate cyclase activity
FT644_RS09565	COG2200	EAL domain
FT644_RS09565	COG2202	Pas domain
FT644_RS09570	COG0840	transmembrane signaling receptor activity
FT644_RS09590	COG4974	Belongs to the 'phage' integrase family
FT644_RS09630	COG0559	Belongs to the binding-protein-dependent transport system permease family
FT644_RS09660	COG0439	Biotin carboxylase
FT644_RS09665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FT644_RS09670	COG1703	isobutyryl-CoA mutase activity
FT644_RS09675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FT644_RS09675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FT644_RS09680	COG1802	Transcriptional regulator
FT644_RS09690	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS09700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FT644_RS09710	COG2878	Part of a membrane complex involved in electron transport
FT644_RS09715	COG0436	Aminotransferase
FT644_RS09720	COG2171	N-acyltransferase activity
FT644_RS09730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FT644_RS09735	COG2890	protein-(glutamine-N5) methyltransferase activity
FT644_RS09750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FT644_RS09775	COG2824	Alkylphosphonate utilization operon protein PhnA
FT644_RS09780	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS09785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FT644_RS09795	COG0508	dehydrogenase complex catalyzes the overall conversion of
FT644_RS09800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FT644_RS09810	COG4566	intracellular signal transduction
FT644_RS09815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FT644_RS09830	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FT644_RS09835	COG0167	dihydroorotate dehydrogenase activity
FT644_RS09875	COG3339	Conserved Protein
FT644_RS09885	COG1752	Esterase of the alpha-beta hydrolase superfamily
FT644_RS09890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FT644_RS09900	COG1196	nuclear chromosome segregation
FT644_RS09905	COG1742	UPF0060 membrane protein
FT644_RS09930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FT644_RS09940	COG2814	Major facilitator Superfamily
FT644_RS09945	COG2814	Major facilitator Superfamily
FT644_RS09960	COG2130	NADP-dependent
FT644_RS09975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FT644_RS09990	COG0590	tRNA wobble adenosine to inosine editing
FT644_RS09995	COG2807	transmembrane transport
FT644_RS10020	COG0633	Ferredoxin
FT644_RS10025	COG0443	Heat shock 70 kDa protein
FT644_RS10040	COG0822	iron-sulfur transferase activity
FT644_RS10045	COG1104	cysteine desulfurase activity
FT644_RS10050	COG1959	2 iron, 2 sulfur cluster binding
FT644_RS10080	COG0564	pseudouridine synthase activity
FT644_RS10085	COG0840	transmembrane signaling receptor activity
FT644_RS10090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FT644_RS10110	COG3177	Filamentation induced by cAMP protein fic
FT644_RS10120	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS10195	COG1612	heme a metabolic process
FT644_RS10200	COG0109	protoheme IX farnesyltransferase activity
FT644_RS10205	COG0667	Aldo Keto reductase
FT644_RS10235	COG2159	amidohydrolase
FT644_RS10240	COG2814	Major facilitator Superfamily
FT644_RS10270	COG0393	Putative heavy-metal-binding
FT644_RS10315	COG1960	acyl-CoA dehydrogenase activity
FT644_RS10335	COG2388	GCN5-related N-acetyl-transferase
FT644_RS10355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT644_RS10370	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FT644_RS10375	COG1115	amino acid carrier protein
FT644_RS10415	COG3384	dioxygenase
FT644_RS10420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FT644_RS10425	COG1570	exodeoxyribonuclease VII activity
FT644_RS10430	COG0811	peptide transport
FT644_RS10440	COG2837	iron assimilation
FT644_RS10465	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS10475	COG1663	tetraacyldisaccharide 4'-kinase activity
FT644_RS10480	COG2835	tetraacyldisaccharide 4'-kinase activity
FT644_RS10485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FT644_RS10490	COG0563	adenylate kinase activity
FT644_RS10495	COG0252	asparaginase activity
FT644_RS10500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FT644_RS10515	COG1530	ribonuclease E activity
FT644_RS10520	COG0424	maF-like protein
FT644_RS10525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FT644_RS10530	COG0799	negative regulation of ribosome biogenesis
FT644_RS10535	COG0408	coproporphyrinogen oxidase activity
FT644_RS10540	COG0151	Belongs to the GarS family
FT644_RS10545	COG0217	transcriptional regulatory protein
FT644_RS10550	COG0433	COG0433 Predicted ATPase
FT644_RS10555	COG1024	Enoyl-CoA hydratase
FT644_RS10565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FT644_RS10580	COG1858	cytochrome C peroxidase
FT644_RS10585	COG4771	TonB-dependent receptor
FT644_RS10595	COG0217	transcriptional regulatory protein
FT644_RS10600	COG2133	pyrroloquinoline quinone binding
FT644_RS10605	COG0700	Nucleoside recognition
FT644_RS10615	COG2925	Exonuclease
FT644_RS10625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FT644_RS10645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FT644_RS10655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FT644_RS10660	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FT644_RS10665	COG4181	ATPase activity
FT644_RS10705	COG1752	Esterase of the alpha-beta hydrolase superfamily
FT644_RS10710	COG1960	acyl-CoA dehydrogenase activity
FT644_RS10715	COG0183	Belongs to the thiolase family
FT644_RS10720	COG1024	Enoyl-CoA hydratase
FT644_RS10720	COG1250	3-hydroxyacyl-CoA dehydrogenase
FT644_RS10735	COG0411	ABC transporter
FT644_RS10745	COG0559	Belongs to the binding-protein-dependent transport system permease family
FT644_RS10770	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS10775	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FT644_RS10780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FT644_RS10785	COG2917	probably involved in intracellular septation
FT644_RS10795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT644_RS10815	COG0351	phosphomethylpyrimidine kinase
FT644_RS10830	COG2022	thiamine diphosphate biosynthetic process
FT644_RS10840	COG3706	GGDEF domain
FT644_RS10845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT644_RS10855	COG1960	acyl-CoA dehydrogenase activity
FT644_RS10865	COG0308	aminopeptidase N
FT644_RS10875	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FT644_RS11045	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FT644_RS11050	COG3657	addiction module killer protein
FT644_RS11055	COG0582	viral genome integration into host DNA
FT644_RS11070	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS11100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FT644_RS11110	COG0583	DNA-binding transcription factor activity
FT644_RS11135	COG1619	proteins homologs of microcin C7 resistance protein MccF
FT644_RS11140	COG0590	tRNA wobble adenosine to inosine editing
FT644_RS11150	COG0826	peptidase U32
FT644_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS11170	COG4221	oxidoreductase activity
FT644_RS11185	COG3047	cAMP biosynthetic process
FT644_RS11190	COG2354	Protein conserved in bacteria
FT644_RS11200	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FT644_RS11205	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FT644_RS11210	COG0714	Associated with various cellular activities
FT644_RS11230	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS11240	COG0047	phosphoribosylformylglycinamidine synthase activity
FT644_RS11240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FT644_RS11245	COG0024	Methionine aminopeptidase
FT644_RS11260	COG0688	phosphatidylethanolamine metabolic process
FT644_RS11265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FT644_RS11285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT644_RS11300	COG3706	GGDEF domain
FT644_RS11350	COG1346	cytolysis
FT644_RS11375	COG3772	lysozyme
FT644_RS11400	COG3039	Transposase
FT644_RS11475	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FT644_RS11485	COG3646	Phage regulatory protein
FT644_RS11580	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FT644_RS11620	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS11640	COG3042	response to heat
FT644_RS11670	COG0776	regulation of translation
FT644_RS11680	COG0322	excinuclease ABC activity
FT644_RS11690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FT644_RS11695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FT644_RS11700	COG0583	DNA-binding transcription factor activity
FT644_RS11710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FT644_RS11715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FT644_RS11720	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FT644_RS11725	COG1414	Transcriptional regulator
FT644_RS11735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FT644_RS11740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FT644_RS11745	COG1183	phosphatidylcholine synthase activity
FT644_RS11750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FT644_RS11755	COG0440	acetolactate synthase activity
FT644_RS11760	COG0028	Belongs to the TPP enzyme family
FT644_RS11785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FT644_RS11795	COG0347	Belongs to the P(II) protein family
FT644_RS11810	COG0840	transmembrane signaling receptor activity
FT644_RS11820	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FT644_RS11830	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS11835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT644_RS11845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FT644_RS11850	COG0746	molybdenum cofactor guanylyltransferase activity
FT644_RS11865	COG0328	RNA-DNA hybrid ribonuclease activity
FT644_RS11870	COG2226	methyltransferase
FT644_RS11875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT644_RS11880	COG1388	LysM domain
FT644_RS11880	COG0741	lytic transglycosylase activity
FT644_RS11885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FT644_RS11890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FT644_RS11895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FT644_RS11910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FT644_RS11925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FT644_RS11935	COG2885	chlorophyll binding
FT644_RS11940	COG0823	Involved in the tonB-independent uptake of proteins
FT644_RS11945	COG1132	(ABC) transporter
FT644_RS11955	COG0084	hydrolase, TatD family'
FT644_RS11970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FT644_RS11975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FT644_RS11980	COG0354	folic acid binding
FT644_RS11985	COG4191	Histidine kinase
FT644_RS11990	COG4566	intracellular signal transduction
FT644_RS12005	COG2153	protein acetylation
FT644_RS12020	COG0628	permease
FT644_RS12035	COG2183	response to ionizing radiation
FT644_RS12045	COG1024	Enoyl-CoA hydratase
FT644_RS12050	COG2832	Protein of unknown function (DUF454)
FT644_RS12055	COG0417	DNA replication proofreading
FT644_RS12065	COG3039	Transposase
FT644_RS12070	COG0583	DNA-binding transcription factor activity
FT644_RS12080	COG0431	NADPH-dependent FMN reductase
FT644_RS12085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FT644_RS12135	COG0789	Transcriptional regulator
FT644_RS12165	COG2132	Multicopper oxidase
FT644_RS12195	COG1464	Belongs to the NlpA lipoprotein family
FT644_RS12200	COG3191	aminopeptidase activity
FT644_RS12210	COG0488	(ABC) transporter
FT644_RS12215	COG0513	Belongs to the DEAD box helicase family
FT644_RS12235	COG3311	Transcriptional regulator
FT644_RS12290	COG0582	viral genome integration into host DNA
FT644_RS12295	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS12310	COG0582	viral genome integration into host DNA
FT644_RS12325	COG3039	Transposase
FT644_RS12335	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS12345	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS12405	COG0582	viral genome integration into host DNA
FT644_RS12420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FT644_RS12435	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FT644_RS12450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FT644_RS12460	COG0776	regulation of translation
FT644_RS12470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FT644_RS12480	COG1322	Protein conserved in bacteria
FT644_RS12490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FT644_RS12500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FT644_RS12505	COG0824	Thioesterase
FT644_RS12615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FT644_RS12640	COG0285	dihydrofolate synthase activity
FT644_RS12645	COG1393	Belongs to the ArsC family
FT644_RS12655	COG3123	guanosine phosphorylase activity
FT644_RS12660	COG0137	argininosuccinate synthase activity
FT644_RS12670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FT644_RS12675	COG4175	Glycine betaine
FT644_RS12680	COG4176	ABC-type proline glycine betaine transport system permease component
FT644_RS12685	COG2113	Glycine betaine
FT644_RS12690	COG2113	Glycine betaine
FT644_RS12695	COG2113	Glycine betaine
FT644_RS12715	COG2814	Major facilitator Superfamily
FT644_RS12720	COG0114	fumarate hydratase activity
FT644_RS12770	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS12780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FT644_RS12790	COG2212	antiporter activity
FT644_RS12795	COG1863	multisubunit Na H antiporter MnhE subunit
FT644_RS12800	COG0651	ATP synthesis coupled electron transport
FT644_RS12805	COG1006	Multisubunit Na H antiporter MnhC subunit
FT644_RS12810	COG2111	Na H antiporter
FT644_RS12810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FT644_RS12830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FT644_RS12835	COG1451	nucleotide metabolic process
FT644_RS12875	COG1960	acyl-CoA dehydrogenase activity
FT644_RS12880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FT644_RS12960	COG1960	acyl-CoA dehydrogenase activity
FT644_RS12965	COG1960	acyl-CoA dehydrogenase activity
FT644_RS12970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT644_RS12980	COG1960	acyl-CoA dehydrogenase activity
FT644_RS12995	COG1960	acyl-CoA dehydrogenase activity
FT644_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS13025	COG0641	radical SAM
FT644_RS13030	COG3039	Transposase
FT644_RS13045	COG3119	arylsulfatase activity
FT644_RS13070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT644_RS13085	COG0446	pyridine nucleotide-disulphide oxidoreductase
FT644_RS13085	COG1902	pentaerythritol trinitrate reductase activity
FT644_RS13090	COG1902	pentaerythritol trinitrate reductase activity
FT644_RS13090	COG0446	pyridine nucleotide-disulphide oxidoreductase
FT644_RS13110	COG1012	belongs to the aldehyde dehydrogenase family
FT644_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS13140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FT644_RS13150	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS13155	COG2814	Major facilitator Superfamily
FT644_RS13160	COG1960	acyl-CoA dehydrogenase activity
FT644_RS13175	COG1250	3-hydroxyacyl-CoA dehydrogenase
FT644_RS13175	COG1024	Enoyl-CoA hydratase
FT644_RS13180	COG0183	Belongs to the thiolase family
FT644_RS13185	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS13195	COG3226	Transcriptional regulator
FT644_RS13200	COG0738	Major facilitator superfamily
FT644_RS13210	COG0183	Belongs to the thiolase family
FT644_RS13225	COG1960	acyl-CoA dehydrogenase activity
FT644_RS13230	COG1960	acyl-CoA dehydrogenase activity
FT644_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS13250	COG0183	Belongs to the thiolase family
FT644_RS13255	COG1960	acyl-CoA dehydrogenase activity
FT644_RS13260	COG1960	acyl-CoA dehydrogenase activity
FT644_RS13275	COG1024	Enoyl-CoA hydratase
FT644_RS13290	COG0346	lactoylglutathione lyase activity
FT644_RS13295	COG1902	pentaerythritol trinitrate reductase activity
FT644_RS13305	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS13310	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS13315	COG3800	Transcriptional regulator
FT644_RS13315	COG1396	sequence-specific DNA binding
FT644_RS13325	COG1802	Transcriptional regulator
FT644_RS13335	COG2828	Protein conserved in bacteria
FT644_RS13345	COG3829	transcription factor binding
FT644_RS13360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT644_RS13375	COG0583	DNA-binding transcription factor activity
FT644_RS13380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FT644_RS13400	COG1294	oxidase, subunit
FT644_RS13410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FT644_RS13415	COG4988	ABC transporter
FT644_RS13440	COG1024	Enoyl-CoA hydratase
FT644_RS13445	COG0123	including yeast histone deacetylase and acetoin utilization protein
FT644_RS13450	COG0714	Associated with various cellular activities
FT644_RS13465	COG2951	lytic endotransglycosylase activity
FT644_RS13475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FT644_RS13490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FT644_RS13500	COG1607	acyl-coa hydrolase
FT644_RS13510	COG2081	HI0933 family
FT644_RS13515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FT644_RS13525	COG0583	DNA-binding transcription factor activity
FT644_RS13530	COG0473	3-isopropylmalate dehydrogenase activity
FT644_RS13560	COG0312	modulator of DNA gyrase
FT644_RS13565	COG3028	Belongs to the UPF0307 family
FT644_RS13570	COG0521	Mo-molybdopterin cofactor biosynthetic process
FT644_RS13600	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS13610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FT644_RS13615	COG0778	Nitroreductase
FT644_RS13615	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FT644_RS13620	COG1045	serine acetyltransferase
FT644_RS13635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FT644_RS13650	COG1968	undecaprenyl-diphosphatase activity
FT644_RS13675	COG1538	Outer membrane efflux protein
FT644_RS13685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FT644_RS13690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT644_RS13705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FT644_RS13710	COG2205	protein histidine kinase activity
FT644_RS13715	COG0745	RESPONSE REGULATOR receiver
FT644_RS13720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT644_RS13830	COG0741	lytic transglycosylase activity
FT644_RS13860	COG4373	Mu-like prophage FluMu protein gp28
FT644_RS13865	COG4383	Mu-like prophage protein gp29
FT644_RS13890	COG4397	Mu-like prophage major head subunit gpT
FT644_RS13970	COG4771	TonB-dependent receptor
FT644_RS13990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FT644_RS13995	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FT644_RS14000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FT644_RS14005	COG0142	geranyltranstransferase activity
FT644_RS14010	COG1722	exodeoxyribonuclease VII activity
FT644_RS14040	COG0745	RESPONSE REGULATOR receiver
FT644_RS14040	COG3706	GGDEF domain
FT644_RS14055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FT644_RS14060	COG0181	hydroxymethylbilane synthase activity
FT644_RS14105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FT644_RS14110	COG0425	Belongs to the sulfur carrier protein TusA family
FT644_RS14140	COG1346	cytolysis
FT644_RS14145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FT644_RS14145	COG0352	thiamine-phosphate diphosphorylase activity
FT644_RS14145	COG0351	phosphomethylpyrimidine kinase
FT644_RS14150	COG0583	DNA-binding transcription factor activity
FT644_RS14155	COG1960	acyl-CoA dehydrogenase activity
FT644_RS14160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FT644_RS14185	COG2910	NAD(P)H-binding
FT644_RS14190	COG0583	DNA-binding transcription factor activity
FT644_RS14235	COG0617	tRNA 3'-terminal CCA addition
FT644_RS14245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FT644_RS14250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FT644_RS14265	COG0728	peptidoglycan biosynthetic process
FT644_RS14270	COG0268	Binds directly to 16S ribosomal RNA
FT644_RS14280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FT644_RS14285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FT644_RS14320	COG0631	protein serine/threonine phosphatase activity
FT644_RS14335	COG1113	amino acid transport
FT644_RS14340	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FT644_RS14350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FT644_RS14355	COG2169	Transcriptional regulator
FT644_RS14355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FT644_RS14360	COG3483	tryptophan 2,3-dioxygenase activity
FT644_RS14370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FT644_RS14375	COG2916	Histone family protein nucleoid-structuring protein H-NS
FT644_RS14405	COG4584	PFAM Integrase catalytic
FT644_RS14405	COG2390	Transcriptional regulator
FT644_RS14410	COG1484	DNA-dependent DNA replication
FT644_RS14415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FT644_RS14420	COG0513	Belongs to the DEAD box helicase family
FT644_RS14425	COG2321	neutral zinc metallopeptidase
FT644_RS14435	COG2423	ornithine cyclodeaminase activity
FT644_RS14440	COG0717	Belongs to the dCTP deaminase family
FT644_RS14445	COG0402	S-adenosylhomocysteine deaminase activity
FT644_RS14455	COG0583	DNA-binding transcription factor activity
FT644_RS14475	COG1304	FMN binding
FT644_RS14480	COG0537	adenosine 5'-monophosphoramidase activity
FT644_RS14485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FT644_RS14515	COG1129	ABC transporter
FT644_RS14525	COG5001	Diguanylate cyclase
FT644_RS14525	COG3447	MASE1 domain protein
FT644_RS14525	COG5002	protein histidine kinase activity
FT644_RS14565	COG0405	Gamma-glutamyltransferase
FT644_RS14575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT644_RS14580	COG1131	(ABC) transporter
FT644_RS14585	COG0842	Transport permease protein
FT644_RS14590	COG0842	Transport permease protein
FT644_RS14595	COG1538	Outer membrane efflux protein
FT644_RS14600	COG2084	Dehydrogenase
FT644_RS14605	COG3622	Belongs to the hyi family
FT644_RS14610	COG3960	tartronate-semialdehyde synthase activity
FT644_RS14615	COG0583	DNA-binding transcription factor activity
FT644_RS14625	COG2186	Transcriptional regulator
FT644_RS14645	COG2233	PERMEase
FT644_RS14650	COG0280	phosphate acetyltransferase
FT644_RS14650	COG0281	malic enzyme
FT644_RS14725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FT644_RS14740	COG5377	YqaJ viral recombinase family
FT644_RS14805	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FT644_RS14845	COG0753	catalase activity
FT644_RS14850	COG0633	Ferredoxin
FT644_RS14850	COG0543	2 iron, 2 sulfur cluster binding
FT644_RS14860	COG1959	2 iron, 2 sulfur cluster binding
FT644_RS14885	COG3039	Transposase
FT644_RS14900	COG3039	Transposase
FT644_RS14915	COG3038	cytochrome b561
FT644_RS14985	COG0668	transmembrane transport
FT644_RS15005	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS15035	COG1250	3-hydroxyacyl-CoA dehydrogenase
FT644_RS15035	COG1024	Enoyl-CoA hydratase
FT644_RS15040	COG2080	2 iron, 2 sulfur cluster binding
FT644_RS15045	COG2010	Cytochrome c
FT644_RS15045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FT644_RS15050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FT644_RS15050	COG2010	Cytochrome c
FT644_RS15055	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FT644_RS15055	COG3608	succinylglutamate desuccinylase aspartoacylase
FT644_RS15070	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FT644_RS15075	COG0425	Belongs to the sulfur carrier protein TusA family
FT644_RS15080	COG2391	methyltransferase activity
FT644_RS15090	COG2188	Transcriptional regulator
FT644_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS15115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FT644_RS15120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FT644_RS15135	COG1561	YicC-like family, N-terminal region
FT644_RS15140	COG0194	GDP metabolic process
FT644_RS15145	COG1758	RNA polymerase activity
FT644_RS15150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FT644_RS15155	COG2951	lytic endotransglycosylase activity
FT644_RS15175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FT644_RS15180	COG1113	amino acid transport
FT644_RS15190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FT644_RS15195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FT644_RS15200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FT644_RS15225	COG1414	Transcriptional regulator
FT644_RS15240	COG2855	membrane
FT644_RS15255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FT644_RS15260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FT644_RS15270	COG2003	Belongs to the UPF0758 family
FT644_RS15285	COG0501	Belongs to the peptidase M48B family
FT644_RS15290	COG1704	LemA family
FT644_RS15305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FT644_RS15310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FT644_RS15325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FT644_RS15340	COG0489	protein tyrosine kinase activity
FT644_RS15360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT644_RS15360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT644_RS15380	COG0446	pyridine nucleotide-disulphide oxidoreductase
FT644_RS15385	COG2391	methyltransferase activity
FT644_RS15435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FT644_RS15450	COG4682	membrane
FT644_RS15480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FT644_RS15490	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FT644_RS15505	COG0659	secondary active sulfate transmembrane transporter activity
FT644_RS15510	COG0583	DNA-binding transcription factor activity
FT644_RS15515	COG0019	diaminopimelate decarboxylase activity
FT644_RS15520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FT644_RS15525	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FT644_RS15530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FT644_RS15535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FT644_RS15540	COG0588	phosphoglycerate mutase activity
FT644_RS15545	COG0793	Belongs to the peptidase S41A family
FT644_RS15550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FT644_RS15560	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS15565	COG2197	response regulator
FT644_RS15575	COG5487	UPF0391 membrane protein
FT644_RS15595	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FT644_RS15600	COG0742	ribosomal rna small subunit methyltransferase
FT644_RS15605	COG0612	Peptidase, M16
FT644_RS15610	COG0612	Peptidase, M16
FT644_RS15625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FT644_RS15630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FT644_RS15635	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS15660	COG1999	signal sequence binding
FT644_RS15665	COG0109	protoheme IX farnesyltransferase activity
FT644_RS15695	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FT644_RS15710	COG2226	methyltransferase
FT644_RS15720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FT644_RS15735	COG1280	lysine exporter protein (LysE YggA)
FT644_RS15755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FT644_RS15835	COG0582	viral genome integration into host DNA
FT644_RS15840	COG2199	diguanylate cyclase activity
FT644_RS15840	COG2203	Gaf domain
FT644_RS15845	COG0642	Histidine kinase
FT644_RS15850	COG0745	RESPONSE REGULATOR receiver
FT644_RS15860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FT644_RS15865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FT644_RS15890	COG0626	cystathionine gamma-synthase activity
FT644_RS15895	COG1522	sequence-specific DNA binding
FT644_RS15905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FT644_RS15910	COG0540	Belongs to the ATCase OTCase family
FT644_RS15915	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FT644_RS15920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FT644_RS15925	COG1678	Uncharacterized ACR, COG1678
FT644_RS15930	COG0415	Belongs to the DNA photolyase family
FT644_RS15960	COG1773	rubredoxin
FT644_RS15970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FT644_RS15975	COG2818	Glycosylase
FT644_RS15980	COG0531	amino acid
FT644_RS15990	COG4654	Cytochrome c, class I
FT644_RS15995	COG0138	bifunctional purine biosynthesis protein purh
FT644_RS16000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FT644_RS16005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FT644_RS16015	COG1238	metal cluster binding
FT644_RS16025	COG3181	Tripartite tricarboxylate transporter family receptor
FT644_RS16040	COG0012	GTP binding
FT644_RS16045	COG0582	viral genome integration into host DNA
FT644_RS16080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FT644_RS16085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FT644_RS16095	COG1024	Enoyl-CoA hydratase
FT644_RS16115	COG2814	Major facilitator Superfamily
FT644_RS16150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FT644_RS16155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FT644_RS16160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT644_RS16170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FT644_RS16190	COG0791	NLP P60 protein
FT644_RS16195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FT644_RS16225	COG5001	Diguanylate cyclase
FT644_RS16225	COG2203	Gaf domain
FT644_RS16225	COG4251	negative regulation of phosphorylation
FT644_RS16225	COG3706	GGDEF domain
FT644_RS16255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FT644_RS16255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FT644_RS16260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FT644_RS16280	COG2264	protein methyltransferase activity
FT644_RS16285	COG0439	Biotin carboxylase
FT644_RS16290	COG0511	ligase activity, forming carbon-carbon bonds
FT644_RS16295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FT644_RS16305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FT644_RS16315	COG3098	single-species biofilm formation
FT644_RS16320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT644_RS16325	COG0312	modulator of DNA gyrase
FT644_RS16330	COG0772	Belongs to the SEDS family
FT644_RS16335	COG3150	esterase
FT644_RS16340	COG0557	exoribonuclease II activity
FT644_RS16350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FT644_RS16355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FT644_RS16360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FT644_RS16370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FT644_RS16375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FT644_RS16385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FT644_RS16390	COG1181	Belongs to the D-alanine--D-alanine ligase family
FT644_RS16395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FT644_RS16400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FT644_RS16405	COG0772	Belongs to the SEDS family
FT644_RS16410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FT644_RS16415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FT644_RS16420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FT644_RS16425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FT644_RS16435	COG3116	cell division
FT644_RS16440	COG0275	rRNA processing
FT644_RS16445	COG2001	Belongs to the MraZ family
FT644_RS16450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FT644_RS16455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FT644_RS16465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FT644_RS16470	COG0523	cobalamin synthesis protein
FT644_RS16475	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FT644_RS16485	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FT644_RS16495	COG1960	acyl-CoA dehydrogenase activity
FT644_RS16515	COG1024	Enoyl-CoA hydratase
FT644_RS16520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FT644_RS16555	COG1132	(ABC) transporter
FT644_RS16565	COG0420	3'-5' exonuclease activity
FT644_RS16570	COG0419	ATPase involved in DNA repair
FT644_RS16575	COG3039	Transposase
FT644_RS16580	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FT644_RS16595	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FT644_RS16600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FT644_RS16615	COG0501	Belongs to the peptidase M48B family
FT644_RS16640	COG0418	dihydroorotase activity
FT644_RS16650	COG0010	Belongs to the arginase family
FT644_RS16655	COG1126	abc transporter atp-binding protein
FT644_RS16660	COG0765	amino acid transport
FT644_RS16665	COG0765	amino acid transport
FT644_RS16670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FT644_RS16675	COG0583	DNA-binding transcription factor activity
FT644_RS16690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FT644_RS16695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FT644_RS16720	COG5265	(ABC) transporter
FT644_RS16725	COG1607	acyl-coa hydrolase
FT644_RS16735	COG2050	protein possibly involved in aromatic compounds catabolism
FT644_RS16740	COG1024	Enoyl-CoA hydratase
FT644_RS16755	COG0183	Belongs to the thiolase family
FT644_RS16760	COG1250	3-hydroxyacyl-CoA dehydrogenase
FT644_RS16760	COG1024	Enoyl-CoA hydratase
FT644_RS16770	COG1960	acyl-CoA dehydrogenase activity
FT644_RS16780	COG1309	transcriptional regulator
FT644_RS16785	COG0642	Histidine kinase
FT644_RS16790	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS16795	COG0745	RESPONSE REGULATOR receiver
FT644_RS16800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FT644_RS16805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FT644_RS16815	COG0463	Glycosyl transferase, family 2
FT644_RS16835	COG2244	polysaccharide biosynthetic process
FT644_RS16840	COG0751	glycine-tRNA ligase activity
FT644_RS16845	COG0752	glycyl-tRNA synthetase alpha subunit
FT644_RS16850	COG4260	virion core protein, lumpy skin disease virus
FT644_RS16880	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FT644_RS16885	COG1652	LysM domain
FT644_RS16890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FT644_RS16910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FT644_RS16920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FT644_RS16925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FT644_RS16940	COG1522	sequence-specific DNA binding
FT644_RS16960	COG3186	Phenylalanine-4-hydroxylase
FT644_RS16965	COG1196	nuclear chromosome segregation
FT644_RS16965	COG3264	Mechanosensitive ion channel
FT644_RS16975	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS17015	COG4774	siderophore transport
FT644_RS17020	COG1196	nuclear chromosome segregation
FT644_RS17020	COG0739	heme binding
FT644_RS17020	COG0741	lytic transglycosylase activity
FT644_RS17040	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FT644_RS17045	COG0625	glutathione transferase activity
FT644_RS17050	COG0617	tRNA 3'-terminal CCA addition
FT644_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
FT644_RS17085	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS17095	COG0037	tRNA processing
FT644_RS17125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FT644_RS17130	COG1473	amidohydrolase
FT644_RS17155	COG1285	pathogenesis
FT644_RS17160	COG2255	four-way junction helicase activity
FT644_RS17165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FT644_RS17170	COG0632	four-way junction helicase activity
FT644_RS17175	COG1702	phosphate starvation-inducible protein PhoH
FT644_RS17180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FT644_RS17195	COG0730	response to heat
FT644_RS17200	COG0513	Belongs to the DEAD box helicase family
FT644_RS17205	COG1490	D-aminoacyl-tRNA deacylase activity
FT644_RS17210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FT644_RS17220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FT644_RS17225	COG3706	GGDEF domain
FT644_RS17230	COG1250	3-hydroxyacyl-CoA dehydrogenase
FT644_RS17240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FT644_RS17250	COG1764	response to oxidative stress
FT644_RS17260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FT644_RS17270	COG1309	transcriptional regulator
FT644_RS17280	COG0326	Molecular chaperone. Has ATPase activity
FT644_RS17285	COG1187	pseudouridine synthase activity
FT644_RS17295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FT644_RS17300	COG1022	Amp-dependent synthetase and ligase
FT644_RS17310	COG0559	Belongs to the binding-protein-dependent transport system permease family
FT644_RS17335	COG3039	Transposase
FT644_RS17350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FT644_RS17365	COG2194	sulfuric ester hydrolase activity
FT644_RS17375	COG1473	amidohydrolase
FT644_RS17385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FT644_RS17390	COG3706	GGDEF domain
FT644_RS17395	COG1231	oxidoreductase activity
FT644_RS17465	COG0583	DNA-binding transcription factor activity
FT644_RS17480	COG0277	FAD linked oxidase domain protein
FT644_RS17520	COG0642	Histidine kinase
FT644_RS17535	COG2733	membrane
FT644_RS17545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FT644_RS17545	COG1017	nitric oxide dioxygenase activity
FT644_RS17555	COG0545	Peptidyl-prolyl cis-trans isomerase
FT644_RS17565	COG4770	biotin carboxylase activity
FT644_RS17570	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS17585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FT644_RS17600	COG2084	Dehydrogenase
FT644_RS17605	COG2823	Periplasmic or secreted lipoprotein
FT644_RS17610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FT644_RS17615	COG0792	nuclease activity
FT644_RS17625	COG0443	Heat shock 70 kDa protein
FT644_RS17635	COG0203	ribosomal protein L17
FT644_RS17640	COG0202	RNA polymerase activity
FT644_RS17645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FT644_RS17650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FT644_RS17655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FT644_RS17660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FT644_RS17665	COG0201	protein transport
FT644_RS17670	COG0200	Binds to the 23S rRNA
FT644_RS17675	COG1841	ribosomal large subunit assembly
FT644_RS17680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FT644_RS17685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FT644_RS17690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FT644_RS17695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FT644_RS17700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FT644_RS17705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FT644_RS17710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FT644_RS17715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FT644_RS17720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FT644_RS17735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FT644_RS17740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FT644_RS17755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FT644_RS17765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FT644_RS17775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FT644_RS17785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FT644_RS17795	COG0134	indole-3-glycerol-phosphate synthase activity
FT644_RS17800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FT644_RS17805	COG0512	Glutamine amidotransferase of anthranilate synthase
FT644_RS17825	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FT644_RS17830	COG0546	phosphoglycolate phosphatase activity
FT644_RS17835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FT644_RS17840	COG2967	ApaG domain
FT644_RS17850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FT644_RS17860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FT644_RS17880	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS17885	COG3039	Transposase
FT644_RS17895	COG2885	chlorophyll binding
FT644_RS17910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FT644_RS17935	COG4964	Belongs to the GSP D family
FT644_RS17985	COG2204	response regulator
FT644_RS18000	COG3012	SEC-C Motif Domain Protein
FT644_RS18000	COG3318	Belongs to the UPF0149 family
FT644_RS18005	COG0069	glutamate synthase activity
FT644_RS18015	COG1301	dicarboxylic acid transport
FT644_RS18045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FT644_RS18055	COG1414	Transcriptional regulator
FT644_RS18075	COG0456	acetyltransferase
FT644_RS18085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FT644_RS18090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FT644_RS18095	COG1028	Short-chain dehydrogenase reductase Sdr
FT644_RS18105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FT644_RS18105	COG0116	Belongs to the methyltransferase superfamily
FT644_RS18110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT644_RS18110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FT644_RS18120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FT644_RS18125	COG1137	ATPase activity
FT644_RS18130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FT644_RS18135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FT644_RS18145	COG0018	arginyl-trna synthetase
FT644_RS18165	COG0745	RESPONSE REGULATOR receiver
FT644_RS18175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FT644_RS18185	COG1942	4-Oxalocrotonate Tautomerase
FT644_RS18190	COG1942	4-Oxalocrotonate Tautomerase
FT644_RS18195	COG0121	glutamine amidotransferase
FT644_RS18225	COG0189	ligase activity
FT644_RS18230	COG3135	benzoate transporter
FT644_RS18235	COG3158	transport of potassium into the cell
FT644_RS18245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FT644_RS18250	COG0569	domain protein
FT644_RS18255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FT644_RS18275	COG0495	leucyl-tRNA aminoacylation
FT644_RS18280	COG0668	transmembrane transport
FT644_RS18285	COG0693	protein deglycase activity
FT644_RS18320	COG3118	belongs to the thioredoxin family
FT644_RS18325	COG3842	ATPase activity
FT644_RS18340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FT644_RS18345	COG0009	L-threonylcarbamoyladenylate synthase
FT644_RS18360	COG1214	PFAM Peptidase M22, glycoprotease
FT644_RS18365	COG0456	acetyltransferase
FT644_RS18375	COG0598	Magnesium transport protein CorA
FT644_RS18380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FT644_RS18390	COG0318	PFAM AMP-dependent synthetase and ligase
FT644_RS18400	COG0642	Histidine kinase
FT644_RS18405	COG0745	RESPONSE REGULATOR receiver
FT644_RS18410	COG0671	phosphoesterase, PA-phosphatase related
FT644_RS18420	COG0671	phosphoesterase, PA-phosphatase related
FT644_RS18425	COG0469	pyruvate kinase activity
FT644_RS18435	COG0006	proline dipeptidase activity
FT644_RS18450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FT644_RS18455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FT644_RS18505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FT644_RS18510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FT644_RS18515	COG0735	belongs to the Fur family
FT644_RS18520	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FT644_RS18530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FT644_RS18535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FT644_RS18550	COG0625	glutathione transferase activity
FT644_RS18565	COG2755	lipolytic protein G-D-S-L family
FT644_RS18565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FT644_RS18610	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS18615	COG1074	ATP-dependent DNA helicase activity
FT644_RS18625	COG1733	regulation of RNA biosynthetic process
FT644_RS18630	COG1335	isochorismatase
FT644_RS18640	COG0386	Belongs to the glutathione peroxidase family
FT644_RS18650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FT644_RS18665	COG0861	Integral membrane protein TerC family
FT644_RS18685	COG4585	Histidine kinase
FT644_RS18690	COG0482	sulfurtransferase activity
FT644_RS18715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FT644_RS18720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FT644_RS18725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FT644_RS18735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FT644_RS18745	COG2267	carboxylic ester hydrolase activity
FT644_RS18755	COG0840	transmembrane signaling receptor activity
FT644_RS18760	COG2813	Specifically methylates the guanine in position
FT644_RS18760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FT644_RS18765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FT644_RS18770	COG2119	membrane
FT644_RS18775	COG0724	RNA recognition motif
FT644_RS18780	COG2826	transposase and inactivated derivatives, IS30 family
FT644_RS18785	COG0724	RNA recognition motif
FT644_RS18795	COG0300	oxidoreductase activity
FT644_RS18815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FT644_RS18830	COG0126	phosphoglycerate kinase activity
FT644_RS18845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FT644_RS18855	COG0242	peptide deformylase activity
FT644_RS18865	COG0758	DNA mediated transformation
FT644_RS18880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FT644_RS18885	COG1862	Preprotein translocase
FT644_RS18895	COG1522	sequence-specific DNA binding
FT644_RS18925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FT644_RS18935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FT644_RS18940	COG0625	glutathione transferase activity
FT644_RS18950	COG4681	YaeQ
FT644_RS18960	COG0861	Integral membrane protein TerC family
FT644_RS18970	COG1950	PFAM Membrane protein of
FT644_RS18975	COG4783	chaperone-mediated protein folding
FT644_RS18980	COG0315	cyclic pyranopterin monophosphate synthase activity
FT644_RS19000	COG0629	single-stranded DNA binding
FT644_RS19005	COG2814	Major facilitator Superfamily
FT644_RS19025	COG0583	DNA-binding transcription factor activity
FT644_RS19030	COG0284	orotidine-5'-phosphate decarboxylase activity
FT644_RS19045	COG0861	Integral membrane protein TerC family
FT644_RS19050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FT644_RS19055	COG0045	succinate-CoA ligase (ADP-forming) activity
FT644_RS19060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FT644_RS19080	COG2137	regulation of response to DNA damage stimulus
FT644_RS19085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FT644_RS19095	COG0745	RESPONSE REGULATOR receiver
FT644_RS19100	COG0642	Histidine kinase
FT644_RS19115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FT644_RS19115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FT644_RS19130	COG2365	Tyrosine phosphatase family
FT644_RS19140	COG0281	malic enzyme
FT644_RS19140	COG0280	phosphate acetyltransferase
FT644_RS19150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FT644_RS19155	COG0706	membrane insertase activity
FT644_RS19160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FT644_RS19170	COG0230	Belongs to the bacterial ribosomal protein bL34 family