locus-tag	class	description
ITJ83_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ITJ83_RS00010	COG0592	DNA-directed DNA polymerase activity
ITJ83_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ITJ83_RS00025	COG0187	DNA topoisomerase II activity
ITJ83_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
ITJ83_RS00040	COG0629	single-stranded DNA binding
ITJ83_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ITJ83_RS00065	COG0359	binds to the 23S rRNA
ITJ83_RS00070	COG0305	Participates in initiation and elongation during chromosome replication
ITJ83_RS00080	COG0702	epimerase
ITJ83_RS00085	COG1959	2 iron, 2 sulfur cluster binding
ITJ83_RS00100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITJ83_RS00105	COG0531	amino acid
ITJ83_RS00110	COG1316	TRANSCRIPTIONal
ITJ83_RS00115	COG0488	(ABC) transporter
ITJ83_RS00140	COG2814	Major facilitator Superfamily
ITJ83_RS00155	COG0730	response to heat
ITJ83_RS00175	COG1846	Transcriptional regulator
ITJ83_RS00180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ITJ83_RS00185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ITJ83_RS00190	COG1780	Probably involved in ribonucleotide reductase function
ITJ83_RS00195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ITJ83_RS00215	COG0194	GDP metabolic process
ITJ83_RS00225	COG0477	Major facilitator Superfamily
ITJ83_RS00230	COG1846	Transcriptional regulator
ITJ83_RS00235	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ITJ83_RS00240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ITJ83_RS00260	COG4608	Belongs to the ABC transporter superfamily
ITJ83_RS00265	COG0444	Belongs to the ABC transporter superfamily
ITJ83_RS00270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ITJ83_RS00275	COG0601	transmembrane transport
ITJ83_RS00280	COG4166	transmembrane transport
ITJ83_RS00285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ITJ83_RS00305	COG1725	Transcriptional regulator
ITJ83_RS00310	COG1131	(ABC) transporter
ITJ83_RS00320	COG1131	(ABC) transporter
ITJ83_RS00345	COG0095	Lipoate-protein ligase
ITJ83_RS00355	COG0667	Aldo Keto reductase
ITJ83_RS00360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ITJ83_RS00365	COG0531	amino acid
ITJ83_RS00380	COG1136	(ABC) transporter
ITJ83_RS00395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITJ83_RS00400	COG0765	amino acid transport
ITJ83_RS00405	COG0765	amino acid transport
ITJ83_RS00410	COG1757	Na H antiporter
ITJ83_RS00420	COG1136	(ABC) transporter
ITJ83_RS00425	COG0577	efflux transmembrane transporter activity
ITJ83_RS00465	COG1447	Phosphotransferase system cellobiose-specific component IIA
ITJ83_RS00470	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS00475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS00475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS00490	COG0626	cystathionine gamma-synthase activity
ITJ83_RS00505	COG2910	NAD(P)H-binding
ITJ83_RS00510	COG0716	FMN binding
ITJ83_RS00530	COG4221	oxidoreductase activity
ITJ83_RS00540	COG3684	Belongs to the aldolase LacD family
ITJ83_RS00545	COG1105	Belongs to the carbohydrate kinase PfkB family
ITJ83_RS00550	COG0698	ribose 5-phosphate isomerase
ITJ83_RS00555	COG0698	ribose 5-phosphate isomerase
ITJ83_RS00560	COG1349	DNA-binding transcription factor activity
ITJ83_RS00595	COG1215	transferase activity, transferring glycosyl groups
ITJ83_RS00610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ITJ83_RS00615	COG2267	carboxylic ester hydrolase activity
ITJ83_RS00645	COG2608	mercury ion transmembrane transporter activity
ITJ83_RS00655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ITJ83_RS00665	COG2116	formate transmembrane transporter activity
ITJ83_RS00670	COG3973	AAA domain
ITJ83_RS00675	COG3706	GGDEF domain
ITJ83_RS00680	COG1376	ErfK ybiS ycfS ynhG family protein
ITJ83_RS00685	COG3976	FMN-binding domain protein
ITJ83_RS00685	COG1053	succinate dehydrogenase
ITJ83_RS00695	COG0583	DNA-binding transcription factor activity
ITJ83_RS00715	COG0519	Catalyzes the synthesis of GMP from XMP
ITJ83_RS00715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ITJ83_RS00805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ITJ83_RS00815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ITJ83_RS00835	COG0778	Nitroreductase
ITJ83_RS00840	COG0583	DNA-binding transcription factor activity
ITJ83_RS00850	COG4221	oxidoreductase activity
ITJ83_RS00855	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS00860	COG3153	acetyltransferase
ITJ83_RS00880	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS00890	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS00905	COG4221	oxidoreductase activity
ITJ83_RS00930	COG2801	Transposase and inactivated derivatives
ITJ83_RS00955	COG0308	aminopeptidase N
ITJ83_RS00960	COG1121	(ABC) transporter
ITJ83_RS00965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ITJ83_RS00970	COG0803	Belongs to the bacterial solute-binding protein 9 family
ITJ83_RS00980	COG0670	Belongs to the BI1 family
ITJ83_RS01020	COG2502	aspartate--ammonia ligase
ITJ83_RS01040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ITJ83_RS01065	COG0505	Belongs to the CarA family
ITJ83_RS01075	COG0419	ATPase involved in DNA repair
ITJ83_RS01080	COG0420	3'-5' exonuclease activity
ITJ83_RS01085	COG4690	dipeptidase activity
ITJ83_RS01090	COG0668	transmembrane transport
ITJ83_RS01110	COG0583	DNA-binding transcription factor activity
ITJ83_RS01115	COG2855	membrane
ITJ83_RS01150	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS01165	COG1914	H( )-stimulated, divalent metal cation uptake system
ITJ83_RS01170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ITJ83_RS01180	COG0702	epimerase
ITJ83_RS01185	COG0110	maltose O-acetyltransferase activity
ITJ83_RS01220	COG1554	hydrolase, family 65, central catalytic
ITJ83_RS01235	COG0300	oxidoreductase activity
ITJ83_RS01240	COG0137	argininosuccinate synthase activity
ITJ83_RS01245	COG0165	Argininosuccinate lyase
ITJ83_RS01265	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ83_RS01290	COG1116	anion transmembrane transporter activity
ITJ83_RS01295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ITJ83_RS01300	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ83_RS01310	COG5002	protein histidine kinase activity
ITJ83_RS01315	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS01320	COG0735	belongs to the Fur family
ITJ83_RS01330	COG1121	(ABC) transporter
ITJ83_RS01345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ITJ83_RS01350	COG0735	belongs to the Fur family
ITJ83_RS01370	COG3118	belongs to the thioredoxin family
ITJ83_RS01385	COG1316	TRANSCRIPTIONal
ITJ83_RS01390	COG2188	Transcriptional regulator
ITJ83_RS01395	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS01410	COG1297	OPT oligopeptide transporter protein
ITJ83_RS01425	COG1760	l-serine dehydratase
ITJ83_RS01430	COG1760	l-serine dehydratase
ITJ83_RS01445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ITJ83_RS01460	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ITJ83_RS01470	COG2188	Transcriptional regulator
ITJ83_RS01475	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ITJ83_RS01490	COG1733	regulation of RNA biosynthetic process
ITJ83_RS01495	COG2814	Major facilitator Superfamily
ITJ83_RS01505	COG4120	Belongs to the binding-protein-dependent transport system permease family
ITJ83_RS01510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ITJ83_RS01515	COG2365	Tyrosine phosphatase family
ITJ83_RS01520	COG1929	Belongs to the glycerate kinase type-1 family
ITJ83_RS01530	COG0519	Catalyzes the synthesis of GMP from XMP
ITJ83_RS01540	COG1137	ATPase activity
ITJ83_RS01560	COG0367	asparagine synthase
ITJ83_RS01590	COG3590	peptidase
ITJ83_RS01610	COG0789	Transcriptional regulator
ITJ83_RS01630	COG3842	ATPase activity
ITJ83_RS01635	COG1175	transmembrane transport
ITJ83_RS01645	COG1653	transport
ITJ83_RS01655	COG0697	spore germination
ITJ83_RS01660	COG4152	abc transporter atp-binding protein
ITJ83_RS01665	COG1668	transmembrane transport
ITJ83_RS01670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ITJ83_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ITJ83_RS01690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ITJ83_RS01700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ITJ83_RS01715	COG1073	alpha beta
ITJ83_RS01720	COG0477	Major facilitator Superfamily
ITJ83_RS01750	COG0028	Belongs to the TPP enzyme family
ITJ83_RS01800	COG0531	amino acid
ITJ83_RS01920	COG1388	LysM domain
ITJ83_RS01920	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITJ83_RS01950	COG0628	permease
ITJ83_RS01970	COG0588	phosphoglycerate mutase activity
ITJ83_RS01995	COG2801	Transposase and inactivated derivatives
ITJ83_RS02015	COG1215	transferase activity, transferring glycosyl groups
ITJ83_RS02050	COG0386	Belongs to the glutathione peroxidase family
ITJ83_RS02055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ITJ83_RS02065	COG0583	DNA-binding transcription factor activity
ITJ83_RS02085	COG2814	Major facilitator Superfamily
ITJ83_RS02100	COG1215	transferase activity, transferring glycosyl groups
ITJ83_RS02115	COG1263	PTS System
ITJ83_RS02115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS02115	COG2190	(PTS) system
ITJ83_RS02125	COG1486	melibiose metabolic process
ITJ83_RS02130	COG1609	Transcriptional regulator
ITJ83_RS02135	COG0697	spore germination
ITJ83_RS02145	COG0697	spore germination
ITJ83_RS02150	COG3527	Alpha-acetolactate decarboxylase
ITJ83_RS02155	COG0028	Belongs to the TPP enzyme family
ITJ83_RS02180	COG1914	H( )-stimulated, divalent metal cation uptake system
ITJ83_RS02190	COG0242	peptide deformylase activity
ITJ83_RS02200	COG1442	glycosyl transferase family 8
ITJ83_RS02235	COG2801	Transposase and inactivated derivatives
ITJ83_RS02240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ITJ83_RS02255	COG0583	DNA-binding transcription factor activity
ITJ83_RS02260	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITJ83_RS02285	COG2217	Heavy metal translocating P-type atpase
ITJ83_RS02300	COG2252	PERMEase
ITJ83_RS02315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ITJ83_RS02370	COG0833	amino acid
ITJ83_RS02375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ITJ83_RS02405	COG1053	succinate dehydrogenase
ITJ83_RS02405	COG3976	FMN-binding domain protein
ITJ83_RS02415	COG0431	NADPH-dependent FMN reductase
ITJ83_RS02415	COG3976	FMN-binding domain protein
ITJ83_RS02415	COG1053	succinate dehydrogenase
ITJ83_RS02425	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITJ83_RS02440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ITJ83_RS02445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ITJ83_RS02450	COG3104	oligopeptide transport
ITJ83_RS02475	COG3201	nicotinamide mononucleotide transporter
ITJ83_RS02480	COG2188	Transcriptional regulator
ITJ83_RS02515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ITJ83_RS02530	COG0436	Aminotransferase
ITJ83_RS02540	COG0463	Glycosyl transferase, family 2
ITJ83_RS02550	COG3091	SprT-like family
ITJ83_RS02600	COG1869	D-ribose catabolic process
ITJ83_RS02610	COG1278	Cold shock
ITJ83_RS02615	COG2814	Major facilitator Superfamily
ITJ83_RS02620	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITJ83_RS02625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ITJ83_RS02630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ITJ83_RS02635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ITJ83_RS02645	COG4978	Transcriptional regulator
ITJ83_RS02645	COG0789	Transcriptional regulator
ITJ83_RS02650	COG0210	DNA helicase
ITJ83_RS02655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ITJ83_RS02660	COG4851	CamS sex pheromone cAM373 precursor
ITJ83_RS02665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ITJ83_RS02675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ITJ83_RS02680	COG1597	lipid kinase activity
ITJ83_RS02685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ITJ83_RS02700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS02710	COG0531	amino acid
ITJ83_RS02715	COG0673	inositol 2-dehydrogenase activity
ITJ83_RS02730	COG1607	acyl-coa hydrolase
ITJ83_RS02765	COG2199	diguanylate cyclase activity
ITJ83_RS02770	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITJ83_RS02790	COG2199	diguanylate cyclase activity
ITJ83_RS02800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ITJ83_RS02820	COG0716	FMN binding
ITJ83_RS02825	COG0024	Methionine aminopeptidase
ITJ83_RS02830	COG1295	ribonuclease BN
ITJ83_RS02835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ITJ83_RS02845	COG0183	Belongs to the thiolase family
ITJ83_RS02855	COG3425	synthase
ITJ83_RS02880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ITJ83_RS02900	COG1609	Transcriptional regulator
ITJ83_RS02905	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ITJ83_RS02910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ITJ83_RS02915	COG1307	EDD domain protein, DegV family
ITJ83_RS02925	COG2188	Transcriptional regulator
ITJ83_RS02945	COG0500	methyltransferase
ITJ83_RS02950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ITJ83_RS02955	COG2137	regulation of response to DNA damage stimulus
ITJ83_RS02965	COG3557	Belongs to the UPF0374 family
ITJ83_RS02970	COG0583	DNA-binding transcription factor activity
ITJ83_RS02980	COG0667	Aldo Keto reductase
ITJ83_RS03000	COG0406	alpha-ribazole phosphatase activity
ITJ83_RS03005	COG0588	phosphoglycerate mutase activity
ITJ83_RS03015	COG1126	abc transporter atp-binding protein
ITJ83_RS03020	COG0765	amino acid transport
ITJ83_RS03025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITJ83_RS03045	COG1253	flavin adenine dinucleotide binding
ITJ83_RS03055	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITJ83_RS03055	COG1388	LysM domain
ITJ83_RS03065	COG1114	Component of the transport system for branched-chain amino acids
ITJ83_RS03105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ITJ83_RS03125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ITJ83_RS03130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ITJ83_RS03135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ITJ83_RS03140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ITJ83_RS03145	COG0131	Imidazoleglycerol-phosphate dehydratase
ITJ83_RS03150	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ITJ83_RS03155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ITJ83_RS03160	COG0107	imidazoleglycerol-phosphate synthase activity
ITJ83_RS03165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ITJ83_RS03170	COG0140	phosphoribosyl-ATP diphosphatase activity
ITJ83_RS03195	COG0306	phosphate transporter
ITJ83_RS03200	COG1392	Phosphate transport regulator
ITJ83_RS03230	COG0542	response to heat
ITJ83_RS03235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS03245	COG1309	transcriptional regulator
ITJ83_RS03250	COG2409	Drug exporters of the RND superfamily
ITJ83_RS03250	COG1033	growth of symbiont in host cell
ITJ83_RS03280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ITJ83_RS03300	COG2205	protein histidine kinase activity
ITJ83_RS03305	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS03310	COG1136	(ABC) transporter
ITJ83_RS03325	COG1234	tRNA 3'-trailer cleavage
ITJ83_RS03330	COG1393	Belongs to the ArsC family
ITJ83_RS03340	COG4862	establishment of competence for transformation
ITJ83_RS03360	COG2357	RelA SpoT domain protein
ITJ83_RS03365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ITJ83_RS03370	COG0564	pseudouridine synthase activity
ITJ83_RS03375	COG2239	Acts as a magnesium transporter
ITJ83_RS03380	COG3142	Participates in the control of copper homeostasis
ITJ83_RS03395	COG2706	6-phosphogluconolactonase activity
ITJ83_RS03400	COG0628	permease
ITJ83_RS03415	COG1674	ftsk spoiiie
ITJ83_RS03420	COG0612	Peptidase, M16
ITJ83_RS03425	COG0612	Peptidase, M16
ITJ83_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ83_RS03435	COG1426	Protein conserved in bacteria
ITJ83_RS03440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ITJ83_RS03445	COG1546	Belongs to the CinA family
ITJ83_RS03445	COG1058	Belongs to the CinA family
ITJ83_RS03450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ITJ83_RS03455	COG1418	mRNA catabolic process
ITJ83_RS03460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITJ83_RS03465	COG3620	sequence-specific DNA binding
ITJ83_RS03470	COG1739	Uncharacterized protein family UPF0029
ITJ83_RS03475	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ITJ83_RS03490	COG0653	protein targeting
ITJ83_RS03500	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS03505	COG5002	protein histidine kinase activity
ITJ83_RS03515	COG0573	inorganic phosphate transmembrane transporter activity
ITJ83_RS03520	COG0581	inorganic phosphate transmembrane transporter activity
ITJ83_RS03525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ITJ83_RS03530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ITJ83_RS03535	COG0704	Plays a role in the regulation of phosphate uptake
ITJ83_RS03540	COG1983	PspC domain protein
ITJ83_RS03545	COG1950	PFAM Membrane protein of
ITJ83_RS03555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ITJ83_RS03560	COG0492	ferredoxin-NADP+ reductase activity
ITJ83_RS03565	COG3620	sequence-specific DNA binding
ITJ83_RS03570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ITJ83_RS03580	COG2270	Major facilitator Superfamily
ITJ83_RS03590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ITJ83_RS03600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ITJ83_RS03605	COG1481	regulation of sporulation
ITJ83_RS03630	COG2814	Major facilitator Superfamily
ITJ83_RS03640	COG0740	serine-type endopeptidase activity
ITJ83_RS03655	COG0583	DNA-binding transcription factor activity
ITJ83_RS03675	COG3052	prosthetic group binding
ITJ83_RS03700	COG2390	Transcriptional regulator
ITJ83_RS03720	COG0148	phosphopyruvate hydratase activity
ITJ83_RS03725	COG0673	inositol 2-dehydrogenase activity
ITJ83_RS03745	COG0557	exoribonuclease II activity
ITJ83_RS03760	COG1619	proteins homologs of microcin C7 resistance protein MccF
ITJ83_RS03780	COG1428	Deoxynucleoside kinase
ITJ83_RS03785	COG4708	membrane
ITJ83_RS03790	COG0438	transferase activity, transferring glycosyl groups
ITJ83_RS03795	COG0438	transferase activity, transferring glycosyl groups
ITJ83_RS03805	COG1368	sulfuric ester hydrolase activity
ITJ83_RS03850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ITJ83_RS03855	COG0527	aspartate kinase activity
ITJ83_RS03860	COG0019	diaminopimelate decarboxylase activity
ITJ83_RS03865	COG2171	N-acyltransferase activity
ITJ83_RS03870	COG1473	amidohydrolase
ITJ83_RS03875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ITJ83_RS03880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ITJ83_RS03885	COG0436	Aminotransferase
ITJ83_RS03890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ITJ83_RS03900	COG1328	CTP reductase activity
ITJ83_RS03905	COG0602	queuosine metabolic process
ITJ83_RS03915	COG2094	Belongs to the DNA glycosylase MPG family
ITJ83_RS03935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ITJ83_RS03940	COG0477	Major facilitator Superfamily
ITJ83_RS03945	COG0671	phosphoesterase, PA-phosphatase related
ITJ83_RS03950	COG1388	LysM domain
ITJ83_RS03950	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITJ83_RS03955	COG0495	leucyl-tRNA aminoacylation
ITJ83_RS03960	COG2244	polysaccharide biosynthetic process
ITJ83_RS03965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ITJ83_RS03975	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITJ83_RS04000	COG5002	protein histidine kinase activity
ITJ83_RS04005	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS04010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ITJ83_RS04045	COG0516	GMP reductase activity
ITJ83_RS04065	COG0582	viral genome integration into host DNA
ITJ83_RS04085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ITJ83_RS04115	COG3646	Phage regulatory protein
ITJ83_RS04395	COG2235	arginine
ITJ83_RS04410	COG0436	Aminotransferase
ITJ83_RS04420	COG0018	arginyl-trna synthetase
ITJ83_RS04425	COG1575	Belongs to the MenA family. Type 1 subfamily
ITJ83_RS04430	COG0564	pseudouridine synthase activity
ITJ83_RS04435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITJ83_RS04445	COG0420	3'-5' exonuclease activity
ITJ83_RS04450	COG4717	serine-type aminopeptidase activity
ITJ83_RS04455	COG3481	metal-dependent phosphohydrolase, HD sub domain
ITJ83_RS04470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ITJ83_RS04480	COG0537	adenosine 5'-monophosphoramidase activity
ITJ83_RS04485	COG1131	(ABC) transporter
ITJ83_RS04495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ITJ83_RS04505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ITJ83_RS04510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITJ83_RS04515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ITJ83_RS04525	COG1228	amidohydrolase
ITJ83_RS04545	COG2814	Major facilitator Superfamily
ITJ83_RS04550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITJ83_RS04550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITJ83_RS04560	COG0237	dephospho-CoA kinase activity
ITJ83_RS04570	COG3611	Membrane attachment protein
ITJ83_RS04575	COG1484	DNA-dependent DNA replication
ITJ83_RS04585	COG0604	alcohol dehydrogenase
ITJ83_RS04590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ITJ83_RS04615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ITJ83_RS04625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ITJ83_RS04630	COG1713	HD superfamily hydrolase involved in NAD metabolism
ITJ83_RS04635	COG0799	negative regulation of ribosome biogenesis
ITJ83_RS04640	COG2226	methyltransferase
ITJ83_RS04645	COG1323	Belongs to the UPF0348 family
ITJ83_RS04655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ITJ83_RS04660	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS04665	COG5002	protein histidine kinase activity
ITJ83_RS04670	COG0706	membrane insertase activity
ITJ83_RS04675	COG1254	Belongs to the acylphosphatase family
ITJ83_RS04680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITJ83_RS04690	COG0072	phenylalanine-tRNA ligase activity
ITJ83_RS04695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ITJ83_RS04700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ITJ83_RS04705	COG4841	protein insertion into membrane
ITJ83_RS04710	COG0768	penicillin binding
ITJ83_RS04715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ITJ83_RS04720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ITJ83_RS04725	COG0705	Rhomboid family
ITJ83_RS04725	COG0457	Tetratricopeptide repeat
ITJ83_RS04735	COG1940	carbohydrate kinase activity
ITJ83_RS04740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ITJ83_RS04750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ITJ83_RS04755	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ITJ83_RS04785	COG2272	Belongs to the type-B carboxylesterase lipase family
ITJ83_RS04800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ITJ83_RS04810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ITJ83_RS04815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ITJ83_RS04825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ITJ83_RS04830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ITJ83_RS04835	COG1570	exodeoxyribonuclease VII activity
ITJ83_RS04840	COG1722	exodeoxyribonuclease VII activity
ITJ83_RS04850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ITJ83_RS04855	COG0497	DNA recombination
ITJ83_RS04865	COG0194	GDP metabolic process
ITJ83_RS04870	COG1758	RNA polymerase activity
ITJ83_RS04875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ITJ83_RS04885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ITJ83_RS04885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ITJ83_RS04890	COG0631	protein serine/threonine phosphatase activity
ITJ83_RS04895	COG0515	serine threonine protein kinase
ITJ83_RS04895	COG2815	serine threonine protein kinase
ITJ83_RS04900	COG1162	GTPase activity
ITJ83_RS04905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ITJ83_RS04920	COG1464	Belongs to the NlpA lipoprotein family
ITJ83_RS04935	COG0693	protein deglycase activity
ITJ83_RS04940	COG0626	cystathionine gamma-synthase activity
ITJ83_RS04950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ITJ83_RS04955	COG1302	Protein conserved in bacteria
ITJ83_RS04965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ITJ83_RS04970	COG0416	fatty acid biosynthetic process
ITJ83_RS04975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ITJ83_RS04980	COG0571	ribonuclease III activity
ITJ83_RS04985	COG1196	nuclear chromosome segregation
ITJ83_RS04990	COG0552	protein localization to endoplasmic reticulum
ITJ83_RS04995	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ITJ83_RS05000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ITJ83_RS05005	COG0228	four-way junction DNA binding
ITJ83_RS05010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ITJ83_RS05015	COG0336	Belongs to the RNA methyltransferase TrmD family
ITJ83_RS05020	COG0335	large ribosomal subunit rRNA binding
ITJ83_RS05025	COG1737	Transcriptional regulator
ITJ83_RS05030	COG0673	inositol 2-dehydrogenase activity
ITJ83_RS05045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ITJ83_RS05050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ITJ83_RS05060	COG4224	UPF0291 protein
ITJ83_RS05070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ITJ83_RS05080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ITJ83_RS05085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ITJ83_RS05090	COG0047	phosphoribosylformylglycinamidine synthase activity
ITJ83_RS05095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ITJ83_RS05105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ITJ83_RS05110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ITJ83_RS05115	COG0138	bifunctional purine biosynthesis protein purh
ITJ83_RS05120	COG0151	Belongs to the GarS family
ITJ83_RS05125	COG0204	Acyl-transferase
ITJ83_RS05130	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ITJ83_RS05135	COG2827	Endonuclease containing a URI domain
ITJ83_RS05140	COG0052	Belongs to the universal ribosomal protein uS2 family
ITJ83_RS05155	COG0233	cytoplasmic translational termination
ITJ83_RS05160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ITJ83_RS05165	COG4589	Belongs to the CDS family
ITJ83_RS05170	COG0750	zinc metalloprotease
ITJ83_RS05175	COG0442	prolyl-tRNA aminoacylation
ITJ83_RS05180	COG2176	DNA-directed DNA polymerase activity
ITJ83_RS05185	COG0779	Required for maturation of 30S ribosomal subunits
ITJ83_RS05190	COG0195	Participates in both transcription termination and antitermination
ITJ83_RS05195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ITJ83_RS05205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ITJ83_RS05210	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ITJ83_RS05215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ITJ83_RS05220	COG0196	riboflavin kinase activity
ITJ83_RS05225	COG1420	regulation of RNA biosynthetic process
ITJ83_RS05230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ITJ83_RS05235	COG0443	Heat shock 70 kDa protein
ITJ83_RS05265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITJ83_RS05270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ITJ83_RS05275	COG3764	Sortase (surface protein transpeptidase)
ITJ83_RS05280	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ITJ83_RS05280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ITJ83_RS05310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ITJ83_RS05330	COG0589	response to stress
ITJ83_RS05340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ITJ83_RS05345	COG1418	mRNA catabolic process
ITJ83_RS05350	COG0450	alkyl hydroperoxide reductase
ITJ83_RS05485	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ITJ83_RS05490	COG3561	AntA/AntB antirepressor
ITJ83_RS05505	COG0629	single-stranded DNA binding
ITJ83_RS05650	COG3842	ATPase activity
ITJ83_RS05670	COG2017	converts alpha-aldose to the beta-anomer
ITJ83_RS05675	COG0346	lactoylglutathione lyase activity
ITJ83_RS05685	COG0561	phosphatase activity
ITJ83_RS05690	COG2271	Major facilitator Superfamily
ITJ83_RS05705	COG1011	Hydrolase
ITJ83_RS05745	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITJ83_RS05750	COG3706	GGDEF domain
ITJ83_RS05750	COG4251	negative regulation of phosphorylation
ITJ83_RS05750	COG2203	Gaf domain
ITJ83_RS05750	COG5001	Diguanylate cyclase
ITJ83_RS05760	COG0488	(ABC) transporter
ITJ83_RS05765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS05775	COG1737	Transcriptional regulator
ITJ83_RS05780	COG1263	PTS System
ITJ83_RS05780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS05780	COG2190	(PTS) system
ITJ83_RS05785	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS05810	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS05815	COG0561	phosphatase activity
ITJ83_RS05825	COG0589	response to stress
ITJ83_RS05830	COG0561	phosphatase activity
ITJ83_RS05835	COG0561	phosphatase activity
ITJ83_RS05850	COG1476	TRANSCRIPTIONal
ITJ83_RS05875	COG2183	response to ionizing radiation
ITJ83_RS05885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITJ83_RS05895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ITJ83_RS05910	COG0148	phosphopyruvate hydratase activity
ITJ83_RS05925	COG4372	Transposase
ITJ83_RS05950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ITJ83_RS05980	COG2801	Transposase and inactivated derivatives
ITJ83_RS05985	COG2264	protein methyltransferase activity
ITJ83_RS05990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ITJ83_RS06000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ITJ83_RS06020	COG2814	Major facilitator Superfamily
ITJ83_RS06025	COG0860	N-Acetylmuramoyl-L-alanine amidase
ITJ83_RS06030	COG0124	histidyl-tRNA synthetase
ITJ83_RS06050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITJ83_RS06055	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ITJ83_RS06060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ITJ83_RS06065	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ITJ83_RS06070	COG1702	phosphate starvation-inducible protein PhoH
ITJ83_RS06090	COG0752	glycyl-tRNA synthetase alpha subunit
ITJ83_RS06095	COG0751	glycine-tRNA ligase activity
ITJ83_RS06105	COG0358	DNA primase activity
ITJ83_RS06110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ITJ83_RS06115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ITJ83_RS06120	COG2384	SAM-dependent methyltransferase
ITJ83_RS06125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ITJ83_RS06130	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITJ83_RS06135	COG1942	4-Oxalocrotonate Tautomerase
ITJ83_RS06155	COG0681	Belongs to the peptidase S26 family
ITJ83_RS06175	COG1304	FMN binding
ITJ83_RS06195	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ITJ83_RS06205	COG1199	ATP-dependent helicase activity
ITJ83_RS06205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ITJ83_RS06225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITJ83_RS06230	COG3331	DNA recombination
ITJ83_RS06250	COG0116	Belongs to the methyltransferase superfamily
ITJ83_RS06260	COG0095	Lipoate-protein ligase
ITJ83_RS06265	COG0328	RNA-DNA hybrid ribonuclease activity
ITJ83_RS06275	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ITJ83_RS06280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ITJ83_RS06285	COG0564	pseudouridine synthase activity
ITJ83_RS06290	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ITJ83_RS06295	COG0505	Belongs to the CarA family
ITJ83_RS06310	COG2801	Transposase and inactivated derivatives
ITJ83_RS06315	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ITJ83_RS06320	COG1307	EDD domain protein, DegV family
ITJ83_RS06370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ITJ83_RS06405	COG4115	mRNA cleavage
ITJ83_RS06415	COG1131	(ABC) transporter
ITJ83_RS06435	COG1473	amidohydrolase
ITJ83_RS06465	COG0514	ATP-dependent DNA helicase (RecQ)
ITJ83_RS06470	COG1309	transcriptional regulator
ITJ83_RS06485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ITJ83_RS06495	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ITJ83_RS06500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS06500	COG1263	PTS System
ITJ83_RS06505	COG1737	Transcriptional regulator
ITJ83_RS06510	COG1263	PTS System
ITJ83_RS06510	COG2190	(PTS) system
ITJ83_RS06510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS06520	COG1611	Belongs to the LOG family
ITJ83_RS06525	COG4975	Glucose uptake
ITJ83_RS06530	COG1227	inorganic diphosphatase activity
ITJ83_RS06545	COG0187	DNA topoisomerase II activity
ITJ83_RS06550	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ITJ83_RS06560	COG1132	(ABC) transporter
ITJ83_RS06595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITJ83_RS06600	COG0758	DNA mediated transformation
ITJ83_RS06605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ITJ83_RS06610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ITJ83_RS06615	COG4479	Belongs to the UPF0346 family
ITJ83_RS06620	COG4698	Protein conserved in bacteria
ITJ83_RS06625	COG2755	lipolytic protein G-D-S-L family
ITJ83_RS06630	COG1307	EDD domain protein, DegV family
ITJ83_RS06635	COG1272	protein, Hemolysin III
ITJ83_RS06640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ITJ83_RS06645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ITJ83_RS06650	COG0488	(ABC) transporter
ITJ83_RS06675	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS06690	COG2223	nitrite transmembrane transporter activity
ITJ83_RS06705	COG0235	Class ii aldolase
ITJ83_RS06710	COG4806	L-rhamnose isomerase
ITJ83_RS06715	COG1070	Carbohydrate kinase
ITJ83_RS06735	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ83_RS06745	COG1917	Cupin 2, conserved barrel domain protein
ITJ83_RS06745	COG2207	Transcriptional regulator
ITJ83_RS06755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS06755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS06755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS06790	COG1757	Na H antiporter
ITJ83_RS06815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ITJ83_RS06825	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ITJ83_RS06835	COG1187	pseudouridine synthase activity
ITJ83_RS06840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ITJ83_RS06845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ITJ83_RS06860	COG2996	Protein conserved in bacteria
ITJ83_RS06875	COG1131	(ABC) transporter
ITJ83_RS06880	COG0842	Transport permease protein
ITJ83_RS06885	COG4585	Histidine kinase
ITJ83_RS06890	COG2197	response regulator
ITJ83_RS06910	COG0587	DNA-directed DNA polymerase activity
ITJ83_RS06935	COG0300	oxidoreductase activity
ITJ83_RS06940	COG1234	tRNA 3'-trailer cleavage
ITJ83_RS06945	COG2755	lipolytic protein G-D-S-L family
ITJ83_RS06945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ITJ83_RS06950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ITJ83_RS06955	COG1349	DNA-binding transcription factor activity
ITJ83_RS06960	COG1105	Belongs to the carbohydrate kinase PfkB family
ITJ83_RS06965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS06965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS06965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS06990	COG3775	system Galactitol-specific IIC component
ITJ83_RS07000	COG2223	nitrite transmembrane transporter activity
ITJ83_RS07005	COG2207	Transcriptional regulator
ITJ83_RS07005	COG1917	Cupin 2, conserved barrel domain protein
ITJ83_RS07010	COG0457	Tetratricopeptide repeat
ITJ83_RS07015	COG2017	converts alpha-aldose to the beta-anomer
ITJ83_RS07025	COG0024	Methionine aminopeptidase
ITJ83_RS07030	COG0322	excinuclease ABC activity
ITJ83_RS07055	COG1285	pathogenesis
ITJ83_RS07065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS07065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS07065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS07080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ITJ83_RS07090	COG0583	DNA-binding transcription factor activity
ITJ83_RS07120	COG1929	Belongs to the glycerate kinase type-1 family
ITJ83_RS07125	COG2610	gluconate transmembrane transporter activity
ITJ83_RS07130	COG3835	regulator
ITJ83_RS07140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ITJ83_RS07145	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS07150	COG0561	phosphatase activity
ITJ83_RS07160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ITJ83_RS07160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ITJ83_RS07165	COG0307	riboflavin synthase, alpha
ITJ83_RS07170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITJ83_RS07170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITJ83_RS07175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ITJ83_RS07200	COG1447	Phosphotransferase system cellobiose-specific component IIA
ITJ83_RS07210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS07210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS07215	COG1447	Phosphotransferase system cellobiose-specific component IIA
ITJ83_RS07220	COG3711	transcriptional antiterminator
ITJ83_RS07225	COG0561	phosphatase activity
ITJ83_RS07235	COG0402	S-adenosylhomocysteine deaminase activity
ITJ83_RS07240	COG2233	PERMEase
ITJ83_RS07245	COG3706	GGDEF domain
ITJ83_RS07270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS07275	COG1737	Transcriptional regulator
ITJ83_RS07280	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS07285	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS07290	COG1447	Phosphotransferase system cellobiose-specific component IIA
ITJ83_RS07295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS07300	COG0561	phosphatase activity
ITJ83_RS07305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ITJ83_RS07310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ITJ83_RS07315	COG1288	antiporter activity
ITJ83_RS07325	COG1607	acyl-coa hydrolase
ITJ83_RS07335	COG1620	l-lactate permease
ITJ83_RS07340	COG0167	dihydroorotate dehydrogenase activity
ITJ83_RS07350	COG0284	orotidine-5'-phosphate decarboxylase activity
ITJ83_RS07355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ITJ83_RS07360	COG0540	Belongs to the ATCase OTCase family
ITJ83_RS07370	COG0588	phosphoglycerate mutase activity
ITJ83_RS07375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ITJ83_RS07380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ITJ83_RS07385	COG0544	peptidyl-prolyl cis-trans isomerase activity
ITJ83_RS07405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ITJ83_RS07415	COG1466	dna polymerase III delta subunit
ITJ83_RS07420	COG0658	competence protein
ITJ83_RS07420	COG2333	competence protein COMEC
ITJ83_RS07425	COG1596	polysaccharide export
ITJ83_RS07425	COG1555	photosystem II stabilization
ITJ83_RS07430	COG3480	Lon protease (S16) C-terminal proteolytic domain
ITJ83_RS07440	COG0742	ribosomal rna small subunit methyltransferase
ITJ83_RS07445	COG4471	UPF0298 protein
ITJ83_RS07450	COG0772	Belongs to the SEDS family
ITJ83_RS07455	COG1217	gtp-binding protein TYPA
ITJ83_RS07480	COG0508	dehydrogenase complex catalyzes the overall conversion of
ITJ83_RS07495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITJ83_RS07500	COG0242	peptide deformylase activity
ITJ83_RS07505	COG5503	Protein of unknown function (DUF1447)
ITJ83_RS07510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ITJ83_RS07515	COG1597	lipid kinase activity
ITJ83_RS07520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ITJ83_RS07530	COG0406	alpha-ribazole phosphatase activity
ITJ83_RS07535	COG0482	sulfurtransferase activity
ITJ83_RS07545	COG1104	cysteine desulfurase activity
ITJ83_RS07560	COG0494	nUDIX hydrolase
ITJ83_RS07575	COG3599	regulation of cell shape
ITJ83_RS07580	COG2302	S4 RNA-binding domain
ITJ83_RS07600	COG0849	cell division
ITJ83_RS07610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ITJ83_RS07620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITJ83_RS07625	COG0768	penicillin binding
ITJ83_RS07635	COG0275	rRNA processing
ITJ83_RS07640	COG2001	Belongs to the MraZ family
ITJ83_RS07655	COG2894	cell division
ITJ83_RS07660	COG0850	regulation of cytokinetic process
ITJ83_RS07670	COG1792	Involved in formation and maintenance of cell shape
ITJ83_RS07675	COG1077	Cell shape determining protein MreB Mrl
ITJ83_RS07690	COG0525	valine-tRNA ligase activity
ITJ83_RS07695	COG0301	tRNA thio-modification
ITJ83_RS07700	COG1104	cysteine desulfurase activity
ITJ83_RS07705	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ITJ83_RS07715	COG4493	Belongs to the UPF0637 family
ITJ83_RS07720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ITJ83_RS07730	COG0589	response to stress
ITJ83_RS07740	COG0509	glycine decarboxylation via glycine cleavage system
ITJ83_RS07745	COG0772	Belongs to the SEDS family
ITJ83_RS07755	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ITJ83_RS07765	COG1077	Cell shape determining protein MreB Mrl
ITJ83_RS07775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ITJ83_RS07785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ITJ83_RS07790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ITJ83_RS07795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ITJ83_RS07805	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ITJ83_RS07810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ITJ83_RS07820	COG0356	it plays a direct role in the translocation of protons across the membrane
ITJ83_RS07825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ITJ83_RS07830	COG0009	L-threonylcarbamoyladenylate synthase
ITJ83_RS07835	COG2890	protein-(glutamine-N5) methyltransferase activity
ITJ83_RS07840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ITJ83_RS07845	COG1435	thymidine kinase activity
ITJ83_RS07850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ITJ83_RS07965	COG0778	Nitroreductase
ITJ83_RS07975	COG1051	belongs to the nudix hydrolase family
ITJ83_RS07995	COG1704	LemA family
ITJ83_RS08000	COG0501	Belongs to the peptidase M48B family
ITJ83_RS08010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ITJ83_RS08015	COG0640	Transcriptional regulator
ITJ83_RS08020	COG1902	pentaerythritol trinitrate reductase activity
ITJ83_RS08020	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITJ83_RS08035	COG0531	amino acid
ITJ83_RS08045	COG0393	Putative heavy-metal-binding
ITJ83_RS08110	COG4974	Belongs to the 'phage' integrase family
ITJ83_RS08180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITJ83_RS08185	COG2814	Major facilitator Superfamily
ITJ83_RS08195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITJ83_RS08205	COG1125	glycine betaine transport
ITJ83_RS08205	COG0517	IMP dehydrogenase activity
ITJ83_RS08230	COG0017	Asparaginyl-tRNA synthetase
ITJ83_RS08260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ITJ83_RS08265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ITJ83_RS08275	COG1132	(ABC) transporter
ITJ83_RS08280	COG1132	(ABC) transporter
ITJ83_RS08285	COG1304	FMN binding
ITJ83_RS08290	COG0569	domain protein
ITJ83_RS08290	COG0475	glutathione-regulated potassium exporter activity
ITJ83_RS08295	COG2814	Major facilitator Superfamily
ITJ83_RS08310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ITJ83_RS08315	COG1063	alcohol dehydrogenase
ITJ83_RS08325	COG1122	ATPase activity
ITJ83_RS08335	COG1902	pentaerythritol trinitrate reductase activity
ITJ83_RS08360	COG0477	Major facilitator Superfamily
ITJ83_RS08375	COG1846	Transcriptional regulator
ITJ83_RS08405	COG2249	NAD(P)H dehydrogenase (quinone) activity
ITJ83_RS08435	COG1070	Carbohydrate kinase
ITJ83_RS08440	COG1263	PTS System
ITJ83_RS08440	COG2190	(PTS) system
ITJ83_RS08440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS08445	COG1554	hydrolase, family 65, central catalytic
ITJ83_RS08460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITJ83_RS08480	COG0561	phosphatase activity
ITJ83_RS08485	COG0561	phosphatase activity
ITJ83_RS08490	COG0110	maltose O-acetyltransferase activity
ITJ83_RS08495	COG2096	Adenosyltransferase
ITJ83_RS08500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ITJ83_RS08530	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ITJ83_RS08535	COG1461	Dihydroxyacetone kinase
ITJ83_RS08540	COG2376	Dihydroxyacetone kinase
ITJ83_RS08545	COG2252	PERMEase
ITJ83_RS08565	COG1114	Component of the transport system for branched-chain amino acids
ITJ83_RS08575	COG0166	Belongs to the GPI family
ITJ83_RS08585	COG1368	sulfuric ester hydrolase activity
ITJ83_RS08590	COG1368	sulfuric ester hydrolase activity
ITJ83_RS08595	COG5002	protein histidine kinase activity
ITJ83_RS08595	COG3850	Histidine kinase
ITJ83_RS08600	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS08605	COG0561	phosphatase activity
ITJ83_RS08625	COG0431	NADPH-dependent FMN reductase
ITJ83_RS08635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ITJ83_RS08640	COG2801	Transposase and inactivated derivatives
ITJ83_RS08655	COG0163	prenyltransferase activity
ITJ83_RS08660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ITJ83_RS08670	COG0210	DNA helicase
ITJ83_RS08675	COG0583	DNA-binding transcription factor activity
ITJ83_RS08685	COG0561	phosphatase activity
ITJ83_RS08705	COG1464	Belongs to the NlpA lipoprotein family
ITJ83_RS08710	COG1464	Belongs to the NlpA lipoprotein family
ITJ83_RS08715	COG2011	ABC-type metal ion transport system permease component
ITJ83_RS08720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ITJ83_RS08770	COG2814	Major facilitator Superfamily
ITJ83_RS08815	COG2814	Major facilitator Superfamily
ITJ83_RS08820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ITJ83_RS08830	COG2076	Multidrug Resistance protein
ITJ83_RS08840	COG0584	glycerophosphoryl diester phosphodiesterase
ITJ83_RS08845	COG2270	Major facilitator Superfamily
ITJ83_RS08850	COG1012	belongs to the aldehyde dehydrogenase family
ITJ83_RS08850	COG1454	alcohol dehydrogenase
ITJ83_RS08860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ITJ83_RS08865	COG0827	DNA restriction-modification system
ITJ83_RS08890	COG4537	Required for transformation and DNA binding
ITJ83_RS08895	COG1459	type II secretion system
ITJ83_RS08900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ITJ83_RS08905	COG0217	transcriptional regulatory protein
ITJ83_RS08920	COG0531	amino acid
ITJ83_RS08925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ITJ83_RS08940	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ITJ83_RS08950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ITJ83_RS08955	COG0708	Exodeoxyribonuclease III
ITJ83_RS08970	COG0802	atpase or kinase
ITJ83_RS08975	COG0280	phosphate acetyltransferase
ITJ83_RS08980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ITJ83_RS08985	COG0561	phosphatase activity
ITJ83_RS09170	COG1098	S1 RNA binding domain
ITJ83_RS09175	COG0492	ferredoxin-NADP+ reductase activity
ITJ83_RS09180	COG0586	Pfam SNARE associated Golgi protein
ITJ83_RS09190	COG0647	UMP catabolic process
ITJ83_RS09195	COG4470	Protein conserved in bacteria
ITJ83_RS09200	COG0737	Belongs to the 5'-nucleotidase family
ITJ83_RS09215	COG0584	glycerophosphoryl diester phosphodiesterase
ITJ83_RS09225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITJ83_RS09235	COG1609	Transcriptional regulator
ITJ83_RS09240	COG0006	proline dipeptidase activity
ITJ83_RS09265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ITJ83_RS09270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ITJ83_RS09280	COG3118	belongs to the thioredoxin family
ITJ83_RS09300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ITJ83_RS09305	COG4472	Bacterial protein of unknown function (DUF965)
ITJ83_RS09315	COG0513	Belongs to the DEAD box helicase family
ITJ83_RS09320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ITJ83_RS09325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ITJ83_RS09330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ITJ83_RS09335	COG1862	Preprotein translocase
ITJ83_RS09340	COG0343	queuine tRNA-ribosyltransferase activity
ITJ83_RS09345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ITJ83_RS09350	COG2255	four-way junction helicase activity
ITJ83_RS09355	COG0632	four-way junction helicase activity
ITJ83_RS09370	COG1692	metallophosphoesterase
ITJ83_RS09405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ITJ83_RS09410	COG1715	Restriction endonuclease
ITJ83_RS09415	COG1811	Na channel or pump
ITJ83_RS09420	COG4978	Transcriptional regulator
ITJ83_RS09420	COG0789	Transcriptional regulator
ITJ83_RS09445	COG1266	CAAX protease self-immunity
ITJ83_RS09465	COG1482	cell wall glycoprotein biosynthetic process
ITJ83_RS09475	COG0488	(ABC) transporter
ITJ83_RS09490	COG2848	UPF0210 protein
ITJ83_RS09510	COG1518	maintenance of DNA repeat elements
ITJ83_RS09520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ITJ83_RS09530	COG1214	PFAM Peptidase M22, glycoprotease
ITJ83_RS09535	COG2801	Transposase and inactivated derivatives
ITJ83_RS09560	COG4467	Involved in initiation control of chromosome replication
ITJ83_RS09565	COG0470	DNA polymerase III
ITJ83_RS09570	COG3870	Protein conserved in bacteria
ITJ83_RS09590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ITJ83_RS09595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ITJ83_RS09605	COG0590	tRNA wobble adenosine to inosine editing
ITJ83_RS09615	COG2813	Specifically methylates the guanine in position
ITJ83_RS09620	COG0222	ribosome binding
ITJ83_RS09625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ITJ83_RS09630	COG0081	regulation of translation
ITJ83_RS09635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ITJ83_RS09640	COG0250	Participates in transcription elongation, termination and antitermination
ITJ83_RS09650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ITJ83_RS09660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITJ83_RS09665	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ITJ83_RS09670	COG0215	cysteine-tRNA ligase activity
ITJ83_RS09680	COG4956	integral membrane protein (PIN domain superfamily)
ITJ83_RS09685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ITJ83_RS09710	COG2936	dipeptidyl-peptidase activity
ITJ83_RS09730	COG0561	phosphatase activity
ITJ83_RS09735	COG4975	Glucose uptake
ITJ83_RS09740	COG0588	phosphoglycerate mutase activity
ITJ83_RS09775	COG3716	PTS system mannose fructose sorbose family IID component
ITJ83_RS09780	COG3715	PTS system
ITJ83_RS09795	COG1263	PTS System
ITJ83_RS09795	COG2190	(PTS) system
ITJ83_RS09795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS09800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ITJ83_RS09805	COG2801	Transposase and inactivated derivatives
ITJ83_RS09825	COG0573	inorganic phosphate transmembrane transporter activity
ITJ83_RS09830	COG0581	inorganic phosphate transmembrane transporter activity
ITJ83_RS09865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITJ83_RS09880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ITJ83_RS09895	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS09900	COG0527	aspartate kinase activity
ITJ83_RS09905	COG0460	homoserine dehydrogenase
ITJ83_RS09920	COG4977	sequence-specific DNA binding
ITJ83_RS09920	COG1917	Cupin 2, conserved barrel domain protein
ITJ83_RS09925	COG2382	esterase
ITJ83_RS09930	COG1263	PTS System
ITJ83_RS09930	COG2190	(PTS) system
ITJ83_RS09930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS09935	COG1349	DNA-binding transcription factor activity
ITJ83_RS09940	COG0546	phosphoglycolate phosphatase activity
ITJ83_RS09945	COG1053	succinate dehydrogenase
ITJ83_RS09950	COG0114	fumarate hydratase activity
ITJ83_RS09955	COG1288	antiporter activity
ITJ83_RS09980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ITJ83_RS09980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ITJ83_RS09985	COG1914	H( )-stimulated, divalent metal cation uptake system
ITJ83_RS09990	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ITJ83_RS09995	COG0439	Biotin carboxylase
ITJ83_RS10005	COG1984	allophanate hydrolase subunit 2
ITJ83_RS10010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ITJ83_RS10015	COG0159	tryptophan synthase activity
ITJ83_RS10045	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ITJ83_RS10050	COG0561	phosphatase activity
ITJ83_RS10080	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ITJ83_RS10085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ITJ83_RS10090	COG0101	tRNA pseudouridine synthase activity
ITJ83_RS10110	COG0203	ribosomal protein L17
ITJ83_RS10125	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ITJ83_RS10130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ITJ83_RS10135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ITJ83_RS10140	COG0563	adenylate kinase activity
ITJ83_RS10150	COG0200	Binds to the 23S rRNA
ITJ83_RS10160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ITJ83_RS10165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ITJ83_RS10170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ITJ83_RS10175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ITJ83_RS10190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ITJ83_RS10200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ITJ83_RS10205	COG0255	Belongs to the universal ribosomal protein uL29 family
ITJ83_RS10210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ITJ83_RS10215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ITJ83_RS10225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ITJ83_RS10230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ITJ83_RS10235	COG0089	rRNA binding
ITJ83_RS10240	COG0088	Forms part of the polypeptide exit tunnel
ITJ83_RS10245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ITJ83_RS10250	COG0051	transcription antitermination factor activity, RNA binding
ITJ83_RS10270	COG0049	tRNA binding
ITJ83_RS10275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ITJ83_RS10300	COG0542	response to heat
ITJ83_RS10325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ITJ83_RS10330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITJ83_RS10335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ITJ83_RS10345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ITJ83_RS10350	COG0037	tRNA processing
ITJ83_RS10355	COG1098	S1 RNA binding domain
ITJ83_RS10365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ITJ83_RS10370	COG2244	polysaccharide biosynthetic process
ITJ83_RS10375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ITJ83_RS10380	COG0193	aminoacyl-tRNA hydrolase activity
ITJ83_RS10385	COG0039	L-malate dehydrogenase activity
ITJ83_RS10395	COG0686	Belongs to the AlaDH PNT family
ITJ83_RS10400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ITJ83_RS10405	COG0736	holo-[acyl-carrier-protein] synthase activity
ITJ83_RS10415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ITJ83_RS10425	COG0254	rRNA binding
ITJ83_RS10430	COG0488	(ABC) transporter
ITJ83_RS10435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ITJ83_RS10445	COG3343	RNA polymerase activity
ITJ83_RS10455	COG0095	Lipoate-protein ligase
ITJ83_RS10460	COG1078	dGTPase activity
ITJ83_RS10465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ITJ83_RS10480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ITJ83_RS10485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ITJ83_RS10490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ITJ83_RS10495	COG4466	Protein conserved in bacteria
ITJ83_RS10505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ITJ83_RS10510	COG0084	hydrolase, TatD family'
ITJ83_RS10515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITJ83_RS10515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITJ83_RS10520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ITJ83_RS10530	COG1881	PFAM PEBP family protein
ITJ83_RS10535	COG0248	Ppx GppA phosphatase
ITJ83_RS10545	COG0390	transport system, permease component
ITJ83_RS10550	COG4619	ABC transporter
ITJ83_RS10570	COG4990	cell redox homeostasis
ITJ83_RS10580	COG2814	Major facilitator Superfamily
ITJ83_RS10595	COG3973	AAA domain
ITJ83_RS10600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ITJ83_RS10665	COG0765	amino acid transport
ITJ83_RS10670	COG1126	abc transporter atp-binding protein
ITJ83_RS10675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITJ83_RS10680	COG1397	ADP-ribosylglycohydrolase
ITJ83_RS10695	COG2807	transmembrane transport
ITJ83_RS10700	COG0546	phosphoglycolate phosphatase activity
ITJ83_RS10710	COG2814	Major facilitator Superfamily
ITJ83_RS10730	COG0628	permease
ITJ83_RS10755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ITJ83_RS10760	COG2086	electron transfer activity
ITJ83_RS10765	COG1960	acyl-CoA dehydrogenase activity
ITJ83_RS10770	COG0789	Transcriptional regulator
ITJ83_RS10775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ITJ83_RS10785	COG1696	Membrane protein involved in D-alanine export
ITJ83_RS10790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ITJ83_RS10800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ITJ83_RS10835	COG2186	Transcriptional regulator
ITJ83_RS10840	COG0366	Alpha amylase catalytic
ITJ83_RS10850	COG2357	RelA SpoT domain protein
ITJ83_RS10855	COG0402	S-adenosylhomocysteine deaminase activity
ITJ83_RS10870	COG2814	Major facilitator Superfamily
ITJ83_RS10885	COG1136	(ABC) transporter
ITJ83_RS10885	COG0577	efflux transmembrane transporter activity
ITJ83_RS10890	COG3428	Bacterial PH domain
ITJ83_RS10925	COG1307	EDD domain protein, DegV family
ITJ83_RS10935	COG0531	amino acid
ITJ83_RS10940	COG0531	amino acid
ITJ83_RS10950	COG0577	efflux transmembrane transporter activity
ITJ83_RS10955	COG1136	(ABC) transporter
ITJ83_RS10965	COG0667	Aldo Keto reductase
ITJ83_RS10970	COG0697	spore germination
ITJ83_RS10980	COG1368	sulfuric ester hydrolase activity
ITJ83_RS10990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITJ83_RS11005	COG2084	Dehydrogenase
ITJ83_RS11030	COG2226	methyltransferase
ITJ83_RS11035	COG2135	peptidase activity
ITJ83_RS11045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ITJ83_RS11050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ITJ83_RS11055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ITJ83_RS11065	COG1253	flavin adenine dinucleotide binding
ITJ83_RS11095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ITJ83_RS11125	COG2723	6-phospho-beta-galactosidase activity
ITJ83_RS11130	COG2190	(PTS) system
ITJ83_RS11130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS11130	COG1263	PTS System
ITJ83_RS11135	COG3711	transcriptional antiterminator
ITJ83_RS11145	COG3655	Transcriptional regulator
ITJ83_RS11165	COG0702	epimerase
ITJ83_RS11170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ITJ83_RS11225	COG1442	glycosyl transferase family 8
ITJ83_RS11225	COG1216	Glycosyl transferase, family 2
ITJ83_RS11230	COG2365	Tyrosine phosphatase family
ITJ83_RS11245	COG0584	glycerophosphoryl diester phosphodiesterase
ITJ83_RS11255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ITJ83_RS11260	COG2222	sugar isomerase
ITJ83_RS11275	COG3716	PTS system mannose fructose sorbose family IID component
ITJ83_RS11280	COG3715	PTS system
ITJ83_RS11285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS11285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS11290	COG2188	Transcriptional regulator
ITJ83_RS11305	COG1181	Belongs to the D-alanine--D-alanine ligase family
ITJ83_RS11315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ITJ83_RS11330	COG0328	RNA-DNA hybrid ribonuclease activity
ITJ83_RS11350	COG2738	Putative neutral zinc metallopeptidase
ITJ83_RS11355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ITJ83_RS11380	COG1131	(ABC) transporter
ITJ83_RS11390	COG0667	Aldo Keto reductase
ITJ83_RS11400	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ITJ83_RS11485	COG3620	sequence-specific DNA binding
ITJ83_RS11510	COG2801	Transposase and inactivated derivatives
ITJ83_RS11550	COG1914	H( )-stimulated, divalent metal cation uptake system
ITJ83_RS11560	COG0861	Integral membrane protein TerC family
ITJ83_RS11565	COG0531	amino acid
ITJ83_RS11570	COG0531	amino acid
ITJ83_RS11585	COG3189	MarR family transcriptional regulator
ITJ83_RS11600	COG1609	Transcriptional regulator
ITJ83_RS11605	COG2226	methyltransferase
ITJ83_RS11610	COG0406	alpha-ribazole phosphatase activity
ITJ83_RS11625	COG0656	L-ascorbic acid biosynthetic process
ITJ83_RS11645	COG2233	PERMEase
ITJ83_RS11655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ITJ83_RS11660	COG0697	spore germination
ITJ83_RS11665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ITJ83_RS11670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITJ83_RS11675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITJ83_RS11685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ITJ83_RS11695	COG2814	Major facilitator Superfamily
ITJ83_RS11700	COG2199	diguanylate cyclase activity
ITJ83_RS11705	COG0477	Major facilitator Superfamily
ITJ83_RS11725	COG1957	nucleoside hydrolase
ITJ83_RS11730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ITJ83_RS11740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ITJ83_RS11745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ITJ83_RS11750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ITJ83_RS11755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ITJ83_RS11790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ITJ83_RS11795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ITJ83_RS11810	COG5002	protein histidine kinase activity
ITJ83_RS11815	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS11835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ITJ83_RS11850	COG0025	NhaP-type Na H and K H
ITJ83_RS11855	COG2040	homocysteine
ITJ83_RS11890	COG2217	Heavy metal translocating P-type atpase
ITJ83_RS11940	COG2190	(PTS) system
ITJ83_RS11945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS11945	COG1263	PTS System
ITJ83_RS11945	COG2190	(PTS) system
ITJ83_RS11955	COG0584	glycerophosphoryl diester phosphodiesterase
ITJ83_RS11980	COG3964	amidohydrolase
ITJ83_RS11990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ITJ83_RS11995	COG2188	Transcriptional regulator
ITJ83_RS12000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ITJ83_RS12005	COG2188	Transcriptional regulator
ITJ83_RS12015	COG0191	fructose-bisphosphate aldolase activity
ITJ83_RS12020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS12020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS12020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS12030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS12030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITJ83_RS12030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITJ83_RS12060	COG3414	Phosphotransferase system galactitol-specific IIB component
ITJ83_RS12065	COG3775	system Galactitol-specific IIC component
ITJ83_RS12085	COG3711	transcriptional antiterminator
ITJ83_RS12120	COG3716	PTS system mannose fructose sorbose family IID component
ITJ83_RS12125	COG3715	PTS system
ITJ83_RS12130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITJ83_RS12135	COG4989	oxidoreductase activity
ITJ83_RS12140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ITJ83_RS12150	COG0366	Alpha amylase catalytic
ITJ83_RS12170	COG4120	Belongs to the binding-protein-dependent transport system permease family
ITJ83_RS12175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ITJ83_RS12205	COG2151	metal-sulfur cluster biosynthetic enzyme
ITJ83_RS12210	COG0719	Fe-S assembly protein
ITJ83_RS12220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ITJ83_RS12255	COG1113	amino acid transport
ITJ83_RS12260	COG0778	Nitroreductase
ITJ83_RS12265	COG1012	belongs to the aldehyde dehydrogenase family
ITJ83_RS12275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ITJ83_RS12280	COG0531	amino acid
ITJ83_RS12285	COG0516	GMP reductase activity
ITJ83_RS12285	COG0517	IMP dehydrogenase activity
ITJ83_RS12305	COG0745	RESPONSE REGULATOR receiver
ITJ83_RS12310	COG5002	protein histidine kinase activity
ITJ83_RS12355	COG2246	polysaccharide biosynthetic process
ITJ83_RS12360	COG1940	carbohydrate kinase activity
ITJ83_RS12365	COG2244	polysaccharide biosynthetic process
ITJ83_RS12405	COG0492	ferredoxin-NADP+ reductase activity
ITJ83_RS12410	COG0640	Transcriptional regulator
ITJ83_RS12420	COG0012	GTP binding
ITJ83_RS12425	COG4481	Protein conserved in bacteria
ITJ83_RS12430	COG1475	DNA binding
ITJ83_RS12435	COG1192	Involved in chromosome partitioning
ITJ83_RS12440	COG0357	Ribosomal RNA small subunit methyltransferase G
ITJ83_RS12445	COG2153	protein acetylation
ITJ83_RS12470	COG3442	glutamine amidotransferase
ITJ83_RS12480	COG4684	Psort location CytoplasmicMembrane, score
ITJ83_RS12485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ITJ83_RS12500	COG0789	Transcriptional regulator
ITJ83_RS12515	COG0351	phosphomethylpyrimidine kinase
ITJ83_RS12530	COG1271	oxidase subunit
ITJ83_RS12535	COG1294	oxidase, subunit
ITJ83_RS12540	COG4988	ABC transporter
ITJ83_RS12545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ITJ83_RS12550	COG0142	geranyltranstransferase activity
ITJ83_RS12570	COG0463	Glycosyl transferase, family 2
ITJ83_RS12585	COG1252	NADH dehydrogenase
ITJ83_RS12595	COG0004	ammonium transporteR
ITJ83_RS12600	COG3158	transport of potassium into the cell
ITJ83_RS12605	COG1335	isochorismatase
ITJ83_RS12620	COG2267	carboxylic ester hydrolase activity
ITJ83_RS12630	COG0363	glucosamine-6-phosphate deaminase activity
ITJ83_RS12635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ITJ83_RS12645	COG0531	amino acid
ITJ83_RS12675	COG0698	ribose 5-phosphate isomerase
ITJ83_RS12690	COG0673	inositol 2-dehydrogenase activity
ITJ83_RS12700	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ITJ83_RS12705	COG1840	ABC-type Fe3 transport system, periplasmic component
ITJ83_RS12720	COG1176	ABC-type spermidine putrescine transport system, permease component I
ITJ83_RS12730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ITJ83_RS12735	COG0706	membrane insertase activity
ITJ83_RS12885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ITJ83_RS12895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ITJ83_RS12950	COG2261	transglycosylase associated protein
ITJ83_RS12965	COG0489	protein tyrosine kinase activity
ITJ83_RS12970	COG4464	protein tyrosine phosphatase activity
ITJ83_RS12975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ITJ83_RS12995	COG1192	Involved in chromosome partitioning
ITJ83_RS13005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ITJ83_RS13020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ITJ83_RS13025	COG0438	transferase activity, transferring glycosyl groups
ITJ83_RS13040	COG0463	Glycosyl transferase, family 2
ITJ83_RS13040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ITJ83_RS13065	COG1192	Involved in chromosome partitioning
ITJ83_RS13105	COG0577	efflux transmembrane transporter activity
ITJ83_RS13110	COG1136	(ABC) transporter
ITJ83_RS13155	COG1309	transcriptional regulator
ITJ83_RS13165	COG1131	(ABC) transporter
ITJ83_RS13170	COG0783	Belongs to the Dps family
ITJ83_RS13260	COG2226	methyltransferase