locus-tag	class	description
IT773_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IT773_RS00010	COG0592	DNA-directed DNA polymerase activity
IT773_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IT773_RS00025	COG0187	DNA topoisomerase II activity
IT773_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
IT773_RS00040	COG0629	single-stranded DNA binding
IT773_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IT773_RS00065	COG0359	binds to the 23S rRNA
IT773_RS00070	COG0305	Participates in initiation and elongation during chromosome replication
IT773_RS00080	COG0702	epimerase
IT773_RS00085	COG1959	2 iron, 2 sulfur cluster binding
IT773_RS00100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IT773_RS00105	COG0531	amino acid
IT773_RS00110	COG1316	TRANSCRIPTIONal
IT773_RS00115	COG0488	(ABC) transporter
IT773_RS00140	COG2814	Major facilitator Superfamily
IT773_RS00155	COG0730	response to heat
IT773_RS00175	COG1846	Transcriptional regulator
IT773_RS00180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IT773_RS00185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IT773_RS00190	COG1780	Probably involved in ribonucleotide reductase function
IT773_RS00195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IT773_RS00215	COG0194	GDP metabolic process
IT773_RS00225	COG0477	Major facilitator Superfamily
IT773_RS00230	COG1846	Transcriptional regulator
IT773_RS00235	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IT773_RS00240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IT773_RS00260	COG4608	Belongs to the ABC transporter superfamily
IT773_RS00265	COG0444	Belongs to the ABC transporter superfamily
IT773_RS00270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IT773_RS00275	COG0601	transmembrane transport
IT773_RS00280	COG4166	transmembrane transport
IT773_RS00285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IT773_RS00305	COG1725	Transcriptional regulator
IT773_RS00310	COG1131	(ABC) transporter
IT773_RS00320	COG1131	(ABC) transporter
IT773_RS00345	COG0095	Lipoate-protein ligase
IT773_RS00355	COG0667	Aldo Keto reductase
IT773_RS00360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IT773_RS00365	COG0531	amino acid
IT773_RS00380	COG1136	(ABC) transporter
IT773_RS00395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT773_RS00400	COG0765	amino acid transport
IT773_RS00405	COG0765	amino acid transport
IT773_RS00410	COG1757	Na H antiporter
IT773_RS00420	COG1136	(ABC) transporter
IT773_RS00425	COG0577	efflux transmembrane transporter activity
IT773_RS00465	COG1447	Phosphotransferase system cellobiose-specific component IIA
IT773_RS00470	COG2723	6-phospho-beta-galactosidase activity
IT773_RS00475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS00475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS00490	COG0626	cystathionine gamma-synthase activity
IT773_RS00505	COG2910	NAD(P)H-binding
IT773_RS00510	COG0716	FMN binding
IT773_RS00530	COG4221	oxidoreductase activity
IT773_RS00540	COG3684	Belongs to the aldolase LacD family
IT773_RS00545	COG1105	Belongs to the carbohydrate kinase PfkB family
IT773_RS00550	COG0698	ribose 5-phosphate isomerase
IT773_RS00555	COG0698	ribose 5-phosphate isomerase
IT773_RS00560	COG1349	DNA-binding transcription factor activity
IT773_RS00595	COG1215	transferase activity, transferring glycosyl groups
IT773_RS00610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IT773_RS00615	COG2267	carboxylic ester hydrolase activity
IT773_RS00645	COG2608	mercury ion transmembrane transporter activity
IT773_RS00655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IT773_RS00665	COG2116	formate transmembrane transporter activity
IT773_RS00670	COG3973	AAA domain
IT773_RS00675	COG3706	GGDEF domain
IT773_RS00680	COG1376	ErfK ybiS ycfS ynhG family protein
IT773_RS00685	COG1053	succinate dehydrogenase
IT773_RS00685	COG3976	FMN-binding domain protein
IT773_RS00695	COG0583	DNA-binding transcription factor activity
IT773_RS00715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IT773_RS00715	COG0519	Catalyzes the synthesis of GMP from XMP
IT773_RS00805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IT773_RS00815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IT773_RS00835	COG0778	Nitroreductase
IT773_RS00840	COG0583	DNA-binding transcription factor activity
IT773_RS00850	COG4221	oxidoreductase activity
IT773_RS00855	COG0656	L-ascorbic acid biosynthetic process
IT773_RS00860	COG3153	acetyltransferase
IT773_RS00880	COG0656	L-ascorbic acid biosynthetic process
IT773_RS00890	COG0656	L-ascorbic acid biosynthetic process
IT773_RS00905	COG4221	oxidoreductase activity
IT773_RS00930	COG2801	Transposase and inactivated derivatives
IT773_RS00955	COG0308	aminopeptidase N
IT773_RS00960	COG1121	(ABC) transporter
IT773_RS00965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IT773_RS00970	COG0803	Belongs to the bacterial solute-binding protein 9 family
IT773_RS00980	COG0670	Belongs to the BI1 family
IT773_RS01020	COG2502	aspartate--ammonia ligase
IT773_RS01040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IT773_RS01070	COG0505	Belongs to the CarA family
IT773_RS01080	COG0419	ATPase involved in DNA repair
IT773_RS01085	COG0420	3'-5' exonuclease activity
IT773_RS01090	COG4690	dipeptidase activity
IT773_RS01095	COG0668	transmembrane transport
IT773_RS01115	COG0583	DNA-binding transcription factor activity
IT773_RS01120	COG2855	membrane
IT773_RS01155	COG0656	L-ascorbic acid biosynthetic process
IT773_RS01170	COG1914	H( )-stimulated, divalent metal cation uptake system
IT773_RS01175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IT773_RS01185	COG0702	epimerase
IT773_RS01190	COG0110	maltose O-acetyltransferase activity
IT773_RS01225	COG1554	hydrolase, family 65, central catalytic
IT773_RS01240	COG0300	oxidoreductase activity
IT773_RS01245	COG0137	argininosuccinate synthase activity
IT773_RS01250	COG0165	Argininosuccinate lyase
IT773_RS01270	COG0318	PFAM AMP-dependent synthetase and ligase
IT773_RS01295	COG1116	anion transmembrane transporter activity
IT773_RS01300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IT773_RS01305	COG0318	PFAM AMP-dependent synthetase and ligase
IT773_RS01315	COG5002	protein histidine kinase activity
IT773_RS01320	COG0745	RESPONSE REGULATOR receiver
IT773_RS01325	COG0735	belongs to the Fur family
IT773_RS01335	COG1121	(ABC) transporter
IT773_RS01350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IT773_RS01355	COG0735	belongs to the Fur family
IT773_RS01375	COG3118	belongs to the thioredoxin family
IT773_RS01390	COG1316	TRANSCRIPTIONal
IT773_RS01395	COG2188	Transcriptional regulator
IT773_RS01400	COG2723	6-phospho-beta-galactosidase activity
IT773_RS01415	COG1297	OPT oligopeptide transporter protein
IT773_RS01430	COG1760	l-serine dehydratase
IT773_RS01435	COG1760	l-serine dehydratase
IT773_RS01450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IT773_RS01465	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IT773_RS01475	COG2188	Transcriptional regulator
IT773_RS01480	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IT773_RS01495	COG1733	regulation of RNA biosynthetic process
IT773_RS01500	COG2814	Major facilitator Superfamily
IT773_RS01510	COG4120	Belongs to the binding-protein-dependent transport system permease family
IT773_RS01515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IT773_RS01520	COG2365	Tyrosine phosphatase family
IT773_RS01525	COG1929	Belongs to the glycerate kinase type-1 family
IT773_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
IT773_RS01545	COG1137	ATPase activity
IT773_RS01565	COG0367	asparagine synthase
IT773_RS01595	COG3590	peptidase
IT773_RS01615	COG0789	Transcriptional regulator
IT773_RS01635	COG3842	ATPase activity
IT773_RS01640	COG1175	transmembrane transport
IT773_RS01650	COG1653	transport
IT773_RS01660	COG0697	spore germination
IT773_RS01665	COG4152	abc transporter atp-binding protein
IT773_RS01670	COG1668	transmembrane transport
IT773_RS01675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IT773_RS01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IT773_RS01695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IT773_RS01705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IT773_RS01720	COG1073	alpha beta
IT773_RS01725	COG0477	Major facilitator Superfamily
IT773_RS01755	COG0028	Belongs to the TPP enzyme family
IT773_RS01805	COG0531	amino acid
IT773_RS01925	COG1388	LysM domain
IT773_RS01925	COG1705	Flagellar rod assembly protein muramidase FlgJ
IT773_RS01955	COG0628	permease
IT773_RS01975	COG0588	phosphoglycerate mutase activity
IT773_RS02000	COG2801	Transposase and inactivated derivatives
IT773_RS02020	COG1215	transferase activity, transferring glycosyl groups
IT773_RS02055	COG0386	Belongs to the glutathione peroxidase family
IT773_RS02060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IT773_RS02070	COG0583	DNA-binding transcription factor activity
IT773_RS02090	COG2814	Major facilitator Superfamily
IT773_RS02105	COG1215	transferase activity, transferring glycosyl groups
IT773_RS02120	COG2190	(PTS) system
IT773_RS02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS02120	COG1263	PTS System
IT773_RS02130	COG1486	melibiose metabolic process
IT773_RS02135	COG1609	Transcriptional regulator
IT773_RS02140	COG0697	spore germination
IT773_RS02150	COG0697	spore germination
IT773_RS02155	COG3527	Alpha-acetolactate decarboxylase
IT773_RS02160	COG0028	Belongs to the TPP enzyme family
IT773_RS02185	COG1914	H( )-stimulated, divalent metal cation uptake system
IT773_RS02195	COG0242	peptide deformylase activity
IT773_RS02205	COG1442	glycosyl transferase family 8
IT773_RS02240	COG2801	Transposase and inactivated derivatives
IT773_RS02245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IT773_RS02260	COG0583	DNA-binding transcription factor activity
IT773_RS02265	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT773_RS02290	COG2217	Heavy metal translocating P-type atpase
IT773_RS02305	COG2252	PERMEase
IT773_RS02320	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IT773_RS02375	COG0833	amino acid
IT773_RS02380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IT773_RS02410	COG3976	FMN-binding domain protein
IT773_RS02410	COG1053	succinate dehydrogenase
IT773_RS02420	COG1053	succinate dehydrogenase
IT773_RS02420	COG0431	NADPH-dependent FMN reductase
IT773_RS02420	COG3976	FMN-binding domain protein
IT773_RS02430	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT773_RS02445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IT773_RS02450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IT773_RS02455	COG3104	oligopeptide transport
IT773_RS02480	COG3201	nicotinamide mononucleotide transporter
IT773_RS02485	COG2188	Transcriptional regulator
IT773_RS02520	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IT773_RS02535	COG0436	Aminotransferase
IT773_RS02545	COG0463	Glycosyl transferase, family 2
IT773_RS02555	COG3091	SprT-like family
IT773_RS02605	COG1869	D-ribose catabolic process
IT773_RS02615	COG1278	Cold shock
IT773_RS02620	COG2814	Major facilitator Superfamily
IT773_RS02625	COG1705	Flagellar rod assembly protein muramidase FlgJ
IT773_RS02630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IT773_RS02635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IT773_RS02640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IT773_RS02650	COG4978	Transcriptional regulator
IT773_RS02650	COG0789	Transcriptional regulator
IT773_RS02655	COG0210	DNA helicase
IT773_RS02660	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IT773_RS02665	COG4851	CamS sex pheromone cAM373 precursor
IT773_RS02670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IT773_RS02680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IT773_RS02685	COG1597	lipid kinase activity
IT773_RS02690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IT773_RS02705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS02715	COG0531	amino acid
IT773_RS02720	COG0673	inositol 2-dehydrogenase activity
IT773_RS02735	COG1607	acyl-coa hydrolase
IT773_RS02770	COG2199	diguanylate cyclase activity
IT773_RS02775	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT773_RS02795	COG2199	diguanylate cyclase activity
IT773_RS02805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IT773_RS02825	COG0716	FMN binding
IT773_RS02830	COG0024	Methionine aminopeptidase
IT773_RS02835	COG1295	ribonuclease BN
IT773_RS02840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IT773_RS02850	COG0183	Belongs to the thiolase family
IT773_RS02860	COG3425	synthase
IT773_RS02885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IT773_RS02905	COG1609	Transcriptional regulator
IT773_RS02910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IT773_RS02915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IT773_RS02920	COG1307	EDD domain protein, DegV family
IT773_RS02930	COG2188	Transcriptional regulator
IT773_RS02950	COG0500	methyltransferase
IT773_RS02955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IT773_RS02960	COG2137	regulation of response to DNA damage stimulus
IT773_RS02970	COG3557	Belongs to the UPF0374 family
IT773_RS02975	COG0583	DNA-binding transcription factor activity
IT773_RS02985	COG0667	Aldo Keto reductase
IT773_RS03005	COG0406	alpha-ribazole phosphatase activity
IT773_RS03010	COG0588	phosphoglycerate mutase activity
IT773_RS03020	COG1126	abc transporter atp-binding protein
IT773_RS03025	COG0765	amino acid transport
IT773_RS03030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT773_RS03050	COG1253	flavin adenine dinucleotide binding
IT773_RS03060	COG1705	Flagellar rod assembly protein muramidase FlgJ
IT773_RS03060	COG1388	LysM domain
IT773_RS03070	COG1114	Component of the transport system for branched-chain amino acids
IT773_RS03110	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IT773_RS03130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IT773_RS03135	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IT773_RS03140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IT773_RS03145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IT773_RS03150	COG0131	Imidazoleglycerol-phosphate dehydratase
IT773_RS03155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IT773_RS03160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IT773_RS03165	COG0107	imidazoleglycerol-phosphate synthase activity
IT773_RS03170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IT773_RS03175	COG0140	phosphoribosyl-ATP diphosphatase activity
IT773_RS03200	COG0306	phosphate transporter
IT773_RS03205	COG1392	Phosphate transport regulator
IT773_RS03230	COG3212	peptidase
IT773_RS03235	COG0542	response to heat
IT773_RS03240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS03250	COG1309	transcriptional regulator
IT773_RS03255	COG1033	growth of symbiont in host cell
IT773_RS03255	COG2409	Drug exporters of the RND superfamily
IT773_RS03285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IT773_RS03305	COG2205	protein histidine kinase activity
IT773_RS03310	COG0745	RESPONSE REGULATOR receiver
IT773_RS03315	COG1136	(ABC) transporter
IT773_RS03330	COG1234	tRNA 3'-trailer cleavage
IT773_RS03335	COG1393	Belongs to the ArsC family
IT773_RS03345	COG4862	establishment of competence for transformation
IT773_RS03365	COG2357	RelA SpoT domain protein
IT773_RS03370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IT773_RS03375	COG0564	pseudouridine synthase activity
IT773_RS03380	COG2239	Acts as a magnesium transporter
IT773_RS03385	COG3142	Participates in the control of copper homeostasis
IT773_RS03400	COG2706	6-phosphogluconolactonase activity
IT773_RS03405	COG0628	permease
IT773_RS03420	COG1674	ftsk spoiiie
IT773_RS03425	COG0612	Peptidase, M16
IT773_RS03430	COG0612	Peptidase, M16
IT773_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
IT773_RS03440	COG1426	Protein conserved in bacteria
IT773_RS03445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IT773_RS03450	COG1546	Belongs to the CinA family
IT773_RS03450	COG1058	Belongs to the CinA family
IT773_RS03455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IT773_RS03460	COG1418	mRNA catabolic process
IT773_RS03465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IT773_RS03470	COG3620	sequence-specific DNA binding
IT773_RS03475	COG1739	Uncharacterized protein family UPF0029
IT773_RS03480	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IT773_RS03495	COG0653	protein targeting
IT773_RS03505	COG0745	RESPONSE REGULATOR receiver
IT773_RS03510	COG5002	protein histidine kinase activity
IT773_RS03520	COG0573	inorganic phosphate transmembrane transporter activity
IT773_RS03525	COG0581	inorganic phosphate transmembrane transporter activity
IT773_RS03530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IT773_RS03535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IT773_RS03540	COG0704	Plays a role in the regulation of phosphate uptake
IT773_RS03545	COG1983	PspC domain protein
IT773_RS03550	COG1950	PFAM Membrane protein of
IT773_RS03560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IT773_RS03565	COG0492	ferredoxin-NADP+ reductase activity
IT773_RS03570	COG3620	sequence-specific DNA binding
IT773_RS03575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IT773_RS03585	COG2270	Major facilitator Superfamily
IT773_RS03595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IT773_RS03605	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IT773_RS03610	COG1481	regulation of sporulation
IT773_RS03635	COG2814	Major facilitator Superfamily
IT773_RS03645	COG0740	serine-type endopeptidase activity
IT773_RS03660	COG0583	DNA-binding transcription factor activity
IT773_RS03680	COG3052	prosthetic group binding
IT773_RS03705	COG2390	Transcriptional regulator
IT773_RS03725	COG0148	phosphopyruvate hydratase activity
IT773_RS03730	COG0673	inositol 2-dehydrogenase activity
IT773_RS03750	COG0557	exoribonuclease II activity
IT773_RS03765	COG1619	proteins homologs of microcin C7 resistance protein MccF
IT773_RS03785	COG1428	Deoxynucleoside kinase
IT773_RS03790	COG4708	membrane
IT773_RS03795	COG0438	transferase activity, transferring glycosyl groups
IT773_RS03800	COG0438	transferase activity, transferring glycosyl groups
IT773_RS03810	COG1368	sulfuric ester hydrolase activity
IT773_RS03855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IT773_RS03860	COG0527	aspartate kinase activity
IT773_RS03865	COG0019	diaminopimelate decarboxylase activity
IT773_RS03870	COG2171	N-acyltransferase activity
IT773_RS03875	COG1473	amidohydrolase
IT773_RS03880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IT773_RS03885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IT773_RS03890	COG0436	Aminotransferase
IT773_RS03895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IT773_RS03905	COG1328	CTP reductase activity
IT773_RS03910	COG0602	queuosine metabolic process
IT773_RS03920	COG2094	Belongs to the DNA glycosylase MPG family
IT773_RS03940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IT773_RS03945	COG0477	Major facilitator Superfamily
IT773_RS03950	COG0671	phosphoesterase, PA-phosphatase related
IT773_RS03955	COG1705	Flagellar rod assembly protein muramidase FlgJ
IT773_RS03955	COG1388	LysM domain
IT773_RS03960	COG0495	leucyl-tRNA aminoacylation
IT773_RS03965	COG2244	polysaccharide biosynthetic process
IT773_RS03970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IT773_RS03980	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT773_RS04005	COG5002	protein histidine kinase activity
IT773_RS04010	COG0745	RESPONSE REGULATOR receiver
IT773_RS04015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IT773_RS04050	COG0516	GMP reductase activity
IT773_RS04070	COG0582	viral genome integration into host DNA
IT773_RS04090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IT773_RS04120	COG3646	Phage regulatory protein
IT773_RS04400	COG2235	arginine
IT773_RS04415	COG0436	Aminotransferase
IT773_RS04425	COG0018	arginyl-trna synthetase
IT773_RS04430	COG1575	Belongs to the MenA family. Type 1 subfamily
IT773_RS04435	COG0564	pseudouridine synthase activity
IT773_RS04440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IT773_RS04450	COG0420	3'-5' exonuclease activity
IT773_RS04455	COG4717	serine-type aminopeptidase activity
IT773_RS04460	COG3481	metal-dependent phosphohydrolase, HD sub domain
IT773_RS04475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IT773_RS04485	COG0537	adenosine 5'-monophosphoramidase activity
IT773_RS04490	COG1131	(ABC) transporter
IT773_RS04500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IT773_RS04510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IT773_RS04515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT773_RS04520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IT773_RS04530	COG1228	amidohydrolase
IT773_RS04550	COG2814	Major facilitator Superfamily
IT773_RS04555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IT773_RS04555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IT773_RS04565	COG0237	dephospho-CoA kinase activity
IT773_RS04575	COG3611	Membrane attachment protein
IT773_RS04580	COG1484	DNA-dependent DNA replication
IT773_RS04590	COG0604	alcohol dehydrogenase
IT773_RS04595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IT773_RS04620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IT773_RS04630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IT773_RS04635	COG1713	HD superfamily hydrolase involved in NAD metabolism
IT773_RS04640	COG0799	negative regulation of ribosome biogenesis
IT773_RS04645	COG2226	methyltransferase
IT773_RS04650	COG1323	Belongs to the UPF0348 family
IT773_RS04660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IT773_RS04665	COG0745	RESPONSE REGULATOR receiver
IT773_RS04670	COG5002	protein histidine kinase activity
IT773_RS04675	COG0706	membrane insertase activity
IT773_RS04680	COG1254	Belongs to the acylphosphatase family
IT773_RS04685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IT773_RS04695	COG0072	phenylalanine-tRNA ligase activity
IT773_RS04700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IT773_RS04705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IT773_RS04710	COG4841	protein insertion into membrane
IT773_RS04715	COG0768	penicillin binding
IT773_RS04720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IT773_RS04725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IT773_RS04730	COG0457	Tetratricopeptide repeat
IT773_RS04730	COG0705	Rhomboid family
IT773_RS04740	COG1940	carbohydrate kinase activity
IT773_RS04745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IT773_RS04755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IT773_RS04760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IT773_RS04790	COG2272	Belongs to the type-B carboxylesterase lipase family
IT773_RS04805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IT773_RS04815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IT773_RS04820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IT773_RS04830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IT773_RS04835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IT773_RS04840	COG1570	exodeoxyribonuclease VII activity
IT773_RS04845	COG1722	exodeoxyribonuclease VII activity
IT773_RS04855	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IT773_RS04860	COG0497	DNA recombination
IT773_RS04870	COG0194	GDP metabolic process
IT773_RS04875	COG1758	RNA polymerase activity
IT773_RS04880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IT773_RS04890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IT773_RS04890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IT773_RS04895	COG0631	protein serine/threonine phosphatase activity
IT773_RS04900	COG2815	serine threonine protein kinase
IT773_RS04900	COG0515	serine threonine protein kinase
IT773_RS04905	COG1162	GTPase activity
IT773_RS04910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IT773_RS04925	COG1464	Belongs to the NlpA lipoprotein family
IT773_RS04940	COG0693	protein deglycase activity
IT773_RS04945	COG0626	cystathionine gamma-synthase activity
IT773_RS04955	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IT773_RS04960	COG1302	Protein conserved in bacteria
IT773_RS04970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IT773_RS04975	COG0416	fatty acid biosynthetic process
IT773_RS04980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IT773_RS04985	COG0571	ribonuclease III activity
IT773_RS04990	COG1196	nuclear chromosome segregation
IT773_RS04995	COG0552	protein localization to endoplasmic reticulum
IT773_RS05000	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IT773_RS05005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IT773_RS05010	COG0228	four-way junction DNA binding
IT773_RS05015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IT773_RS05020	COG0336	Belongs to the RNA methyltransferase TrmD family
IT773_RS05025	COG0335	large ribosomal subunit rRNA binding
IT773_RS05030	COG1737	Transcriptional regulator
IT773_RS05035	COG0673	inositol 2-dehydrogenase activity
IT773_RS05050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IT773_RS05055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IT773_RS05065	COG4224	UPF0291 protein
IT773_RS05075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IT773_RS05085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IT773_RS05090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IT773_RS05095	COG0047	phosphoribosylformylglycinamidine synthase activity
IT773_RS05100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IT773_RS05110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IT773_RS05115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IT773_RS05120	COG0138	bifunctional purine biosynthesis protein purh
IT773_RS05125	COG0151	Belongs to the GarS family
IT773_RS05130	COG0204	Acyl-transferase
IT773_RS05135	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IT773_RS05140	COG2827	Endonuclease containing a URI domain
IT773_RS05145	COG0052	Belongs to the universal ribosomal protein uS2 family
IT773_RS05160	COG0233	cytoplasmic translational termination
IT773_RS05165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IT773_RS05170	COG4589	Belongs to the CDS family
IT773_RS05175	COG0750	zinc metalloprotease
IT773_RS05180	COG0442	prolyl-tRNA aminoacylation
IT773_RS05185	COG2176	DNA-directed DNA polymerase activity
IT773_RS05190	COG0779	Required for maturation of 30S ribosomal subunits
IT773_RS05195	COG0195	Participates in both transcription termination and antitermination
IT773_RS05200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IT773_RS05210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IT773_RS05215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IT773_RS05220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IT773_RS05225	COG0196	riboflavin kinase activity
IT773_RS05230	COG1420	regulation of RNA biosynthetic process
IT773_RS05235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IT773_RS05240	COG0443	Heat shock 70 kDa protein
IT773_RS05270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IT773_RS05275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IT773_RS05280	COG3764	Sortase (surface protein transpeptidase)
IT773_RS05285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IT773_RS05285	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IT773_RS05315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IT773_RS05335	COG0589	response to stress
IT773_RS05345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IT773_RS05350	COG1418	mRNA catabolic process
IT773_RS05355	COG0450	alkyl hydroperoxide reductase
IT773_RS05490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IT773_RS05495	COG3561	AntA/AntB antirepressor
IT773_RS05510	COG0629	single-stranded DNA binding
IT773_RS05655	COG3842	ATPase activity
IT773_RS05675	COG2017	converts alpha-aldose to the beta-anomer
IT773_RS05680	COG0346	lactoylglutathione lyase activity
IT773_RS05690	COG0561	phosphatase activity
IT773_RS05695	COG2271	Major facilitator Superfamily
IT773_RS05750	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT773_RS05755	COG5001	Diguanylate cyclase
IT773_RS05755	COG2203	Gaf domain
IT773_RS05755	COG3706	GGDEF domain
IT773_RS05755	COG4251	negative regulation of phosphorylation
IT773_RS05765	COG0488	(ABC) transporter
IT773_RS05770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS05780	COG1737	Transcriptional regulator
IT773_RS05785	COG1263	PTS System
IT773_RS05785	COG2190	(PTS) system
IT773_RS05785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS05790	COG2723	6-phospho-beta-galactosidase activity
IT773_RS05815	COG0656	L-ascorbic acid biosynthetic process
IT773_RS05820	COG0561	phosphatase activity
IT773_RS05830	COG0589	response to stress
IT773_RS05835	COG0561	phosphatase activity
IT773_RS05840	COG0561	phosphatase activity
IT773_RS05855	COG1476	TRANSCRIPTIONal
IT773_RS05880	COG2183	response to ionizing radiation
IT773_RS05890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IT773_RS05900	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IT773_RS05915	COG0148	phosphopyruvate hydratase activity
IT773_RS05930	COG4372	Transposase
IT773_RS05955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IT773_RS05985	COG2801	Transposase and inactivated derivatives
IT773_RS05990	COG2264	protein methyltransferase activity
IT773_RS05995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IT773_RS06005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IT773_RS06025	COG2814	Major facilitator Superfamily
IT773_RS06030	COG0860	N-Acetylmuramoyl-L-alanine amidase
IT773_RS06035	COG0124	histidyl-tRNA synthetase
IT773_RS06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IT773_RS06060	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IT773_RS06065	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IT773_RS06070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IT773_RS06075	COG1702	phosphate starvation-inducible protein PhoH
IT773_RS06095	COG0752	glycyl-tRNA synthetase alpha subunit
IT773_RS06100	COG0751	glycine-tRNA ligase activity
IT773_RS06110	COG0358	DNA primase activity
IT773_RS06115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IT773_RS06120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IT773_RS06125	COG2384	SAM-dependent methyltransferase
IT773_RS06130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IT773_RS06135	COG2195	Cleaves the N-terminal amino acid of tripeptides
IT773_RS06140	COG1942	4-Oxalocrotonate Tautomerase
IT773_RS06160	COG0681	Belongs to the peptidase S26 family
IT773_RS06180	COG1304	FMN binding
IT773_RS06200	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IT773_RS06210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IT773_RS06210	COG1199	ATP-dependent helicase activity
IT773_RS06230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IT773_RS06235	COG3331	DNA recombination
IT773_RS06255	COG0116	Belongs to the methyltransferase superfamily
IT773_RS06265	COG0095	Lipoate-protein ligase
IT773_RS06270	COG0328	RNA-DNA hybrid ribonuclease activity
IT773_RS06280	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IT773_RS06285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IT773_RS06290	COG0564	pseudouridine synthase activity
IT773_RS06295	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IT773_RS06300	COG0505	Belongs to the CarA family
IT773_RS06315	COG2801	Transposase and inactivated derivatives
IT773_RS06320	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IT773_RS06325	COG1307	EDD domain protein, DegV family
IT773_RS06375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IT773_RS06410	COG4115	mRNA cleavage
IT773_RS06420	COG1131	(ABC) transporter
IT773_RS06440	COG1473	amidohydrolase
IT773_RS06470	COG0514	ATP-dependent DNA helicase (RecQ)
IT773_RS06475	COG1309	transcriptional regulator
IT773_RS06490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IT773_RS06500	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IT773_RS06505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS06505	COG1263	PTS System
IT773_RS06510	COG1737	Transcriptional regulator
IT773_RS06515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS06515	COG2190	(PTS) system
IT773_RS06515	COG1263	PTS System
IT773_RS06525	COG1611	Belongs to the LOG family
IT773_RS06530	COG4975	Glucose uptake
IT773_RS06535	COG1227	inorganic diphosphatase activity
IT773_RS06550	COG0187	DNA topoisomerase II activity
IT773_RS06555	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IT773_RS06565	COG1132	(ABC) transporter
IT773_RS06600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IT773_RS06605	COG0758	DNA mediated transformation
IT773_RS06610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IT773_RS06615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IT773_RS06620	COG4479	Belongs to the UPF0346 family
IT773_RS06625	COG4698	Protein conserved in bacteria
IT773_RS06630	COG2755	lipolytic protein G-D-S-L family
IT773_RS06635	COG1307	EDD domain protein, DegV family
IT773_RS06640	COG1272	protein, Hemolysin III
IT773_RS06645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IT773_RS06650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IT773_RS06655	COG0488	(ABC) transporter
IT773_RS06680	COG2723	6-phospho-beta-galactosidase activity
IT773_RS06695	COG2223	nitrite transmembrane transporter activity
IT773_RS06710	COG0235	Class ii aldolase
IT773_RS06715	COG4806	L-rhamnose isomerase
IT773_RS06720	COG1070	Carbohydrate kinase
IT773_RS06740	COG1472	Belongs to the glycosyl hydrolase 3 family
IT773_RS06750	COG1917	Cupin 2, conserved barrel domain protein
IT773_RS06750	COG2207	Transcriptional regulator
IT773_RS06760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS06760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS06760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS06795	COG1757	Na H antiporter
IT773_RS06820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IT773_RS06830	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IT773_RS06840	COG1187	pseudouridine synthase activity
IT773_RS06845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IT773_RS06850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IT773_RS06865	COG2996	Protein conserved in bacteria
IT773_RS06880	COG1131	(ABC) transporter
IT773_RS06885	COG0842	Transport permease protein
IT773_RS06890	COG4585	Histidine kinase
IT773_RS06895	COG2197	response regulator
IT773_RS06915	COG0587	DNA-directed DNA polymerase activity
IT773_RS06940	COG0300	oxidoreductase activity
IT773_RS06945	COG1234	tRNA 3'-trailer cleavage
IT773_RS06950	COG2755	lipolytic protein G-D-S-L family
IT773_RS06950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IT773_RS06955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IT773_RS06960	COG1349	DNA-binding transcription factor activity
IT773_RS06965	COG1105	Belongs to the carbohydrate kinase PfkB family
IT773_RS06970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS06970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS06970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS06995	COG3775	system Galactitol-specific IIC component
IT773_RS07005	COG2223	nitrite transmembrane transporter activity
IT773_RS07010	COG1917	Cupin 2, conserved barrel domain protein
IT773_RS07010	COG2207	Transcriptional regulator
IT773_RS07015	COG0457	Tetratricopeptide repeat
IT773_RS07020	COG2017	converts alpha-aldose to the beta-anomer
IT773_RS07030	COG0024	Methionine aminopeptidase
IT773_RS07035	COG0322	excinuclease ABC activity
IT773_RS07060	COG1285	pathogenesis
IT773_RS07070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS07070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS07070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS07085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IT773_RS07095	COG0583	DNA-binding transcription factor activity
IT773_RS07125	COG1929	Belongs to the glycerate kinase type-1 family
IT773_RS07130	COG2610	gluconate transmembrane transporter activity
IT773_RS07135	COG3835	regulator
IT773_RS07145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IT773_RS07150	COG0656	L-ascorbic acid biosynthetic process
IT773_RS07155	COG0561	phosphatase activity
IT773_RS07165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IT773_RS07165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IT773_RS07170	COG0307	riboflavin synthase, alpha
IT773_RS07175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IT773_RS07175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IT773_RS07180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IT773_RS07205	COG1447	Phosphotransferase system cellobiose-specific component IIA
IT773_RS07215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS07215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS07220	COG1447	Phosphotransferase system cellobiose-specific component IIA
IT773_RS07225	COG3711	transcriptional antiterminator
IT773_RS07230	COG0561	phosphatase activity
IT773_RS07240	COG0402	S-adenosylhomocysteine deaminase activity
IT773_RS07245	COG2233	PERMEase
IT773_RS07250	COG3706	GGDEF domain
IT773_RS07275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS07280	COG1737	Transcriptional regulator
IT773_RS07285	COG2723	6-phospho-beta-galactosidase activity
IT773_RS07290	COG2723	6-phospho-beta-galactosidase activity
IT773_RS07295	COG1447	Phosphotransferase system cellobiose-specific component IIA
IT773_RS07300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS07305	COG0561	phosphatase activity
IT773_RS07310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IT773_RS07315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IT773_RS07320	COG1288	antiporter activity
IT773_RS07330	COG1607	acyl-coa hydrolase
IT773_RS07340	COG1620	l-lactate permease
IT773_RS07345	COG0167	dihydroorotate dehydrogenase activity
IT773_RS07355	COG0284	orotidine-5'-phosphate decarboxylase activity
IT773_RS07360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IT773_RS07365	COG0540	Belongs to the ATCase OTCase family
IT773_RS07375	COG0588	phosphoglycerate mutase activity
IT773_RS07380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IT773_RS07385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IT773_RS07390	COG0544	peptidyl-prolyl cis-trans isomerase activity
IT773_RS07410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IT773_RS07420	COG1466	dna polymerase III delta subunit
IT773_RS07425	COG0658	competence protein
IT773_RS07425	COG2333	competence protein COMEC
IT773_RS07430	COG1596	polysaccharide export
IT773_RS07430	COG1555	photosystem II stabilization
IT773_RS07435	COG3480	Lon protease (S16) C-terminal proteolytic domain
IT773_RS07445	COG0742	ribosomal rna small subunit methyltransferase
IT773_RS07450	COG4471	UPF0298 protein
IT773_RS07455	COG0772	Belongs to the SEDS family
IT773_RS07460	COG1217	gtp-binding protein TYPA
IT773_RS07485	COG0508	dehydrogenase complex catalyzes the overall conversion of
IT773_RS07500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IT773_RS07505	COG0242	peptide deformylase activity
IT773_RS07510	COG5503	Protein of unknown function (DUF1447)
IT773_RS07515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IT773_RS07520	COG1597	lipid kinase activity
IT773_RS07525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IT773_RS07535	COG0406	alpha-ribazole phosphatase activity
IT773_RS07540	COG0482	sulfurtransferase activity
IT773_RS07550	COG1104	cysteine desulfurase activity
IT773_RS07565	COG0494	nUDIX hydrolase
IT773_RS07580	COG3599	regulation of cell shape
IT773_RS07585	COG2302	S4 RNA-binding domain
IT773_RS07605	COG0849	cell division
IT773_RS07615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IT773_RS07625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IT773_RS07630	COG0768	penicillin binding
IT773_RS07640	COG0275	rRNA processing
IT773_RS07645	COG2001	Belongs to the MraZ family
IT773_RS07660	COG2894	cell division
IT773_RS07665	COG0850	regulation of cytokinetic process
IT773_RS07675	COG1792	Involved in formation and maintenance of cell shape
IT773_RS07680	COG1077	Cell shape determining protein MreB Mrl
IT773_RS07695	COG0525	valine-tRNA ligase activity
IT773_RS07700	COG0301	tRNA thio-modification
IT773_RS07705	COG1104	cysteine desulfurase activity
IT773_RS07710	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IT773_RS07720	COG4493	Belongs to the UPF0637 family
IT773_RS07725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IT773_RS07735	COG0589	response to stress
IT773_RS07745	COG0509	glycine decarboxylation via glycine cleavage system
IT773_RS07750	COG0772	Belongs to the SEDS family
IT773_RS07760	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IT773_RS07770	COG1077	Cell shape determining protein MreB Mrl
IT773_RS07780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IT773_RS07790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IT773_RS07795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IT773_RS07800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IT773_RS07810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IT773_RS07815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IT773_RS07825	COG0356	it plays a direct role in the translocation of protons across the membrane
IT773_RS07830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IT773_RS07835	COG0009	L-threonylcarbamoyladenylate synthase
IT773_RS07840	COG2890	protein-(glutamine-N5) methyltransferase activity
IT773_RS07845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IT773_RS07850	COG1435	thymidine kinase activity
IT773_RS07855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IT773_RS07970	COG0778	Nitroreductase
IT773_RS07980	COG1051	belongs to the nudix hydrolase family
IT773_RS08000	COG1704	LemA family
IT773_RS08005	COG0501	Belongs to the peptidase M48B family
IT773_RS08015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IT773_RS08020	COG0640	Transcriptional regulator
IT773_RS08025	COG1902	pentaerythritol trinitrate reductase activity
IT773_RS08025	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT773_RS08040	COG0531	amino acid
IT773_RS08050	COG0393	Putative heavy-metal-binding
IT773_RS08115	COG4974	Belongs to the 'phage' integrase family
IT773_RS08185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IT773_RS08190	COG2814	Major facilitator Superfamily
IT773_RS08200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IT773_RS08210	COG1125	glycine betaine transport
IT773_RS08210	COG0517	IMP dehydrogenase activity
IT773_RS08235	COG0017	Asparaginyl-tRNA synthetase
IT773_RS08265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IT773_RS08270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IT773_RS08280	COG1132	(ABC) transporter
IT773_RS08285	COG1132	(ABC) transporter
IT773_RS08290	COG1304	FMN binding
IT773_RS08295	COG0569	domain protein
IT773_RS08295	COG0475	glutathione-regulated potassium exporter activity
IT773_RS08300	COG2814	Major facilitator Superfamily
IT773_RS08315	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IT773_RS08320	COG1063	alcohol dehydrogenase
IT773_RS08330	COG1122	ATPase activity
IT773_RS08340	COG1902	pentaerythritol trinitrate reductase activity
IT773_RS08365	COG0477	Major facilitator Superfamily
IT773_RS08380	COG1846	Transcriptional regulator
IT773_RS08410	COG2249	NAD(P)H dehydrogenase (quinone) activity
IT773_RS08440	COG1070	Carbohydrate kinase
IT773_RS08445	COG2190	(PTS) system
IT773_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS08445	COG1263	PTS System
IT773_RS08450	COG1554	hydrolase, family 65, central catalytic
IT773_RS08465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IT773_RS08485	COG0561	phosphatase activity
IT773_RS08490	COG0561	phosphatase activity
IT773_RS08495	COG0110	maltose O-acetyltransferase activity
IT773_RS08500	COG2096	Adenosyltransferase
IT773_RS08505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IT773_RS08535	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IT773_RS08540	COG1461	Dihydroxyacetone kinase
IT773_RS08545	COG2376	Dihydroxyacetone kinase
IT773_RS08550	COG2252	PERMEase
IT773_RS08570	COG1114	Component of the transport system for branched-chain amino acids
IT773_RS08580	COG0166	Belongs to the GPI family
IT773_RS08590	COG1368	sulfuric ester hydrolase activity
IT773_RS08595	COG1368	sulfuric ester hydrolase activity
IT773_RS08600	COG5002	protein histidine kinase activity
IT773_RS08600	COG3850	Histidine kinase
IT773_RS08605	COG0745	RESPONSE REGULATOR receiver
IT773_RS08610	COG0561	phosphatase activity
IT773_RS08630	COG0431	NADPH-dependent FMN reductase
IT773_RS08640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IT773_RS08645	COG2801	Transposase and inactivated derivatives
IT773_RS08660	COG0163	prenyltransferase activity
IT773_RS08665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IT773_RS08675	COG0210	DNA helicase
IT773_RS08680	COG0583	DNA-binding transcription factor activity
IT773_RS08690	COG0561	phosphatase activity
IT773_RS08710	COG1464	Belongs to the NlpA lipoprotein family
IT773_RS08715	COG1464	Belongs to the NlpA lipoprotein family
IT773_RS08720	COG2011	ABC-type metal ion transport system permease component
IT773_RS08725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IT773_RS08775	COG2814	Major facilitator Superfamily
IT773_RS08820	COG2814	Major facilitator Superfamily
IT773_RS08825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IT773_RS08835	COG2076	Multidrug Resistance protein
IT773_RS08845	COG0584	glycerophosphoryl diester phosphodiesterase
IT773_RS08850	COG2270	Major facilitator Superfamily
IT773_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
IT773_RS08855	COG1454	alcohol dehydrogenase
IT773_RS08865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IT773_RS08870	COG0827	DNA restriction-modification system
IT773_RS08895	COG4537	Required for transformation and DNA binding
IT773_RS08900	COG1459	type II secretion system
IT773_RS08905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IT773_RS08910	COG0217	transcriptional regulatory protein
IT773_RS08925	COG0531	amino acid
IT773_RS08930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IT773_RS08945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IT773_RS08955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IT773_RS08960	COG0708	Exodeoxyribonuclease III
IT773_RS08975	COG0802	atpase or kinase
IT773_RS08980	COG0280	phosphate acetyltransferase
IT773_RS08985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IT773_RS08990	COG0561	phosphatase activity
IT773_RS09175	COG1098	S1 RNA binding domain
IT773_RS09180	COG0492	ferredoxin-NADP+ reductase activity
IT773_RS09185	COG0586	Pfam SNARE associated Golgi protein
IT773_RS09195	COG0647	UMP catabolic process
IT773_RS09200	COG4470	Protein conserved in bacteria
IT773_RS09205	COG0737	Belongs to the 5'-nucleotidase family
IT773_RS09220	COG0584	glycerophosphoryl diester phosphodiesterase
IT773_RS09230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IT773_RS09240	COG1609	Transcriptional regulator
IT773_RS09245	COG0006	proline dipeptidase activity
IT773_RS09270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IT773_RS09275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IT773_RS09285	COG3118	belongs to the thioredoxin family
IT773_RS09305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IT773_RS09310	COG4472	Bacterial protein of unknown function (DUF965)
IT773_RS09320	COG0513	Belongs to the DEAD box helicase family
IT773_RS09325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IT773_RS09330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IT773_RS09335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IT773_RS09340	COG1862	Preprotein translocase
IT773_RS09345	COG0343	queuine tRNA-ribosyltransferase activity
IT773_RS09350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IT773_RS09355	COG2255	four-way junction helicase activity
IT773_RS09360	COG0632	four-way junction helicase activity
IT773_RS09375	COG1692	metallophosphoesterase
IT773_RS09410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IT773_RS09415	COG1715	Restriction endonuclease
IT773_RS09420	COG1811	Na channel or pump
IT773_RS09425	COG4978	Transcriptional regulator
IT773_RS09425	COG0789	Transcriptional regulator
IT773_RS09450	COG1266	CAAX protease self-immunity
IT773_RS09470	COG1482	cell wall glycoprotein biosynthetic process
IT773_RS09480	COG0488	(ABC) transporter
IT773_RS09495	COG2848	UPF0210 protein
IT773_RS09515	COG1518	maintenance of DNA repeat elements
IT773_RS09525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IT773_RS09535	COG1214	PFAM Peptidase M22, glycoprotease
IT773_RS09540	COG2801	Transposase and inactivated derivatives
IT773_RS09565	COG4467	Involved in initiation control of chromosome replication
IT773_RS09570	COG0470	DNA polymerase III
IT773_RS09575	COG3870	Protein conserved in bacteria
IT773_RS09595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IT773_RS09600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IT773_RS09610	COG0590	tRNA wobble adenosine to inosine editing
IT773_RS09620	COG2813	Specifically methylates the guanine in position
IT773_RS09625	COG0222	ribosome binding
IT773_RS09630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IT773_RS09635	COG0081	regulation of translation
IT773_RS09640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IT773_RS09645	COG0250	Participates in transcription elongation, termination and antitermination
IT773_RS09655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IT773_RS09665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IT773_RS09670	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IT773_RS09675	COG0215	cysteine-tRNA ligase activity
IT773_RS09685	COG4956	integral membrane protein (PIN domain superfamily)
IT773_RS09690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IT773_RS09715	COG2936	dipeptidyl-peptidase activity
IT773_RS09735	COG0561	phosphatase activity
IT773_RS09740	COG4975	Glucose uptake
IT773_RS09745	COG0588	phosphoglycerate mutase activity
IT773_RS09780	COG3716	PTS system mannose fructose sorbose family IID component
IT773_RS09785	COG3715	PTS system
IT773_RS09800	COG2190	(PTS) system
IT773_RS09800	COG1263	PTS System
IT773_RS09800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS09805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IT773_RS09810	COG2801	Transposase and inactivated derivatives
IT773_RS09830	COG0573	inorganic phosphate transmembrane transporter activity
IT773_RS09835	COG0581	inorganic phosphate transmembrane transporter activity
IT773_RS09870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IT773_RS09885	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IT773_RS09900	COG0656	L-ascorbic acid biosynthetic process
IT773_RS09905	COG0527	aspartate kinase activity
IT773_RS09910	COG0460	homoserine dehydrogenase
IT773_RS09925	COG4977	sequence-specific DNA binding
IT773_RS09925	COG1917	Cupin 2, conserved barrel domain protein
IT773_RS09930	COG2382	esterase
IT773_RS09935	COG2190	(PTS) system
IT773_RS09935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS09935	COG1263	PTS System
IT773_RS09940	COG1349	DNA-binding transcription factor activity
IT773_RS09945	COG0546	phosphoglycolate phosphatase activity
IT773_RS09950	COG1053	succinate dehydrogenase
IT773_RS09955	COG0114	fumarate hydratase activity
IT773_RS09960	COG1288	antiporter activity
IT773_RS09985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IT773_RS09985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IT773_RS09990	COG1914	H( )-stimulated, divalent metal cation uptake system
IT773_RS09995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IT773_RS10000	COG0439	Biotin carboxylase
IT773_RS10010	COG1984	allophanate hydrolase subunit 2
IT773_RS10015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IT773_RS10020	COG0159	tryptophan synthase activity
IT773_RS10050	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IT773_RS10055	COG0561	phosphatase activity
IT773_RS10085	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IT773_RS10090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IT773_RS10095	COG0101	tRNA pseudouridine synthase activity
IT773_RS10115	COG0203	ribosomal protein L17
IT773_RS10130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IT773_RS10135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IT773_RS10140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IT773_RS10145	COG0563	adenylate kinase activity
IT773_RS10155	COG0200	Binds to the 23S rRNA
IT773_RS10165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IT773_RS10170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IT773_RS10175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IT773_RS10180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IT773_RS10195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IT773_RS10205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IT773_RS10210	COG0255	Belongs to the universal ribosomal protein uL29 family
IT773_RS10215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IT773_RS10220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IT773_RS10230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IT773_RS10235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IT773_RS10240	COG0089	rRNA binding
IT773_RS10245	COG0088	Forms part of the polypeptide exit tunnel
IT773_RS10250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IT773_RS10255	COG0051	transcription antitermination factor activity, RNA binding
IT773_RS10275	COG0049	tRNA binding
IT773_RS10280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IT773_RS10305	COG0542	response to heat
IT773_RS10330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IT773_RS10335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IT773_RS10340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IT773_RS10350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IT773_RS10355	COG0037	tRNA processing
IT773_RS10360	COG1098	S1 RNA binding domain
IT773_RS10370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IT773_RS10375	COG2244	polysaccharide biosynthetic process
IT773_RS10380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IT773_RS10385	COG0193	aminoacyl-tRNA hydrolase activity
IT773_RS10390	COG0039	L-malate dehydrogenase activity
IT773_RS10400	COG0686	Belongs to the AlaDH PNT family
IT773_RS10405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IT773_RS10410	COG0736	holo-[acyl-carrier-protein] synthase activity
IT773_RS10420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IT773_RS10430	COG0254	rRNA binding
IT773_RS10435	COG0488	(ABC) transporter
IT773_RS10440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IT773_RS10450	COG3343	RNA polymerase activity
IT773_RS10460	COG0095	Lipoate-protein ligase
IT773_RS10465	COG1078	dGTPase activity
IT773_RS10470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IT773_RS10485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IT773_RS10490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IT773_RS10495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IT773_RS10500	COG4466	Protein conserved in bacteria
IT773_RS10510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IT773_RS10515	COG0084	hydrolase, TatD family'
IT773_RS10520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT773_RS10520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT773_RS10525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IT773_RS10535	COG1881	PFAM PEBP family protein
IT773_RS10540	COG0248	Ppx GppA phosphatase
IT773_RS10550	COG0390	transport system, permease component
IT773_RS10555	COG4619	ABC transporter
IT773_RS10575	COG4990	cell redox homeostasis
IT773_RS10585	COG2814	Major facilitator Superfamily
IT773_RS10600	COG3973	AAA domain
IT773_RS10605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT773_RS10670	COG0765	amino acid transport
IT773_RS10675	COG1126	abc transporter atp-binding protein
IT773_RS10680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT773_RS10685	COG1397	ADP-ribosylglycohydrolase
IT773_RS10700	COG2807	transmembrane transport
IT773_RS10705	COG0546	phosphoglycolate phosphatase activity
IT773_RS10715	COG2814	Major facilitator Superfamily
IT773_RS10735	COG0628	permease
IT773_RS10760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IT773_RS10765	COG2086	electron transfer activity
IT773_RS10770	COG1960	acyl-CoA dehydrogenase activity
IT773_RS10775	COG0789	Transcriptional regulator
IT773_RS10780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IT773_RS10790	COG1696	Membrane protein involved in D-alanine export
IT773_RS10795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IT773_RS10805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IT773_RS10840	COG2186	Transcriptional regulator
IT773_RS10845	COG0366	Alpha amylase catalytic
IT773_RS10855	COG2357	RelA SpoT domain protein
IT773_RS10860	COG0402	S-adenosylhomocysteine deaminase activity
IT773_RS10875	COG2814	Major facilitator Superfamily
IT773_RS10890	COG0577	efflux transmembrane transporter activity
IT773_RS10890	COG1136	(ABC) transporter
IT773_RS10895	COG3428	Bacterial PH domain
IT773_RS10930	COG1307	EDD domain protein, DegV family
IT773_RS10940	COG0531	amino acid
IT773_RS10945	COG0531	amino acid
IT773_RS10955	COG0577	efflux transmembrane transporter activity
IT773_RS10960	COG1136	(ABC) transporter
IT773_RS10970	COG0667	Aldo Keto reductase
IT773_RS10975	COG0697	spore germination
IT773_RS10985	COG1368	sulfuric ester hydrolase activity
IT773_RS10995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IT773_RS11010	COG2084	Dehydrogenase
IT773_RS11035	COG2226	methyltransferase
IT773_RS11040	COG2135	peptidase activity
IT773_RS11050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IT773_RS11055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IT773_RS11060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IT773_RS11070	COG1253	flavin adenine dinucleotide binding
IT773_RS11100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IT773_RS11130	COG2723	6-phospho-beta-galactosidase activity
IT773_RS11135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS11135	COG1263	PTS System
IT773_RS11135	COG2190	(PTS) system
IT773_RS11140	COG3711	transcriptional antiterminator
IT773_RS11150	COG3655	Transcriptional regulator
IT773_RS11170	COG0702	epimerase
IT773_RS11175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IT773_RS11230	COG1442	glycosyl transferase family 8
IT773_RS11230	COG1216	Glycosyl transferase, family 2
IT773_RS11235	COG2365	Tyrosine phosphatase family
IT773_RS11250	COG0584	glycerophosphoryl diester phosphodiesterase
IT773_RS11260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IT773_RS11265	COG2222	sugar isomerase
IT773_RS11280	COG3716	PTS system mannose fructose sorbose family IID component
IT773_RS11285	COG3715	PTS system
IT773_RS11290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS11290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS11295	COG2188	Transcriptional regulator
IT773_RS11310	COG1181	Belongs to the D-alanine--D-alanine ligase family
IT773_RS11320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IT773_RS11335	COG0328	RNA-DNA hybrid ribonuclease activity
IT773_RS11355	COG2738	Putative neutral zinc metallopeptidase
IT773_RS11360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IT773_RS11385	COG1131	(ABC) transporter
IT773_RS11395	COG0667	Aldo Keto reductase
IT773_RS11405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IT773_RS11490	COG3620	sequence-specific DNA binding
IT773_RS11515	COG2801	Transposase and inactivated derivatives
IT773_RS11555	COG1914	H( )-stimulated, divalent metal cation uptake system
IT773_RS11565	COG0861	Integral membrane protein TerC family
IT773_RS11570	COG0531	amino acid
IT773_RS11575	COG0531	amino acid
IT773_RS11590	COG3189	MarR family transcriptional regulator
IT773_RS11605	COG1609	Transcriptional regulator
IT773_RS11610	COG2226	methyltransferase
IT773_RS11615	COG0406	alpha-ribazole phosphatase activity
IT773_RS11630	COG0656	L-ascorbic acid biosynthetic process
IT773_RS11650	COG2233	PERMEase
IT773_RS11660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IT773_RS11665	COG0697	spore germination
IT773_RS11670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IT773_RS11675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IT773_RS11680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IT773_RS11690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IT773_RS11700	COG2814	Major facilitator Superfamily
IT773_RS11705	COG2199	diguanylate cyclase activity
IT773_RS11710	COG0477	Major facilitator Superfamily
IT773_RS11730	COG1957	nucleoside hydrolase
IT773_RS11735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IT773_RS11745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IT773_RS11750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IT773_RS11755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IT773_RS11760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IT773_RS11795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IT773_RS11800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IT773_RS11815	COG5002	protein histidine kinase activity
IT773_RS11820	COG0745	RESPONSE REGULATOR receiver
IT773_RS11840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IT773_RS11855	COG0025	NhaP-type Na H and K H
IT773_RS11860	COG2040	homocysteine
IT773_RS11890	COG2217	Heavy metal translocating P-type atpase
IT773_RS11940	COG2190	(PTS) system
IT773_RS11945	COG2190	(PTS) system
IT773_RS11945	COG1263	PTS System
IT773_RS11945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS11955	COG0584	glycerophosphoryl diester phosphodiesterase
IT773_RS11980	COG3964	amidohydrolase
IT773_RS11990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT773_RS11995	COG2188	Transcriptional regulator
IT773_RS12000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IT773_RS12005	COG2188	Transcriptional regulator
IT773_RS12015	COG0191	fructose-bisphosphate aldolase activity
IT773_RS12020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS12020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS12020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS12030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT773_RS12030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS12030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT773_RS12060	COG3414	Phosphotransferase system galactitol-specific IIB component
IT773_RS12065	COG3775	system Galactitol-specific IIC component
IT773_RS12085	COG3711	transcriptional antiterminator
IT773_RS12120	COG3716	PTS system mannose fructose sorbose family IID component
IT773_RS12125	COG3715	PTS system
IT773_RS12130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT773_RS12135	COG4989	oxidoreductase activity
IT773_RS12140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IT773_RS12150	COG0366	Alpha amylase catalytic
IT773_RS12170	COG4120	Belongs to the binding-protein-dependent transport system permease family
IT773_RS12175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IT773_RS12205	COG2151	metal-sulfur cluster biosynthetic enzyme
IT773_RS12210	COG0719	Fe-S assembly protein
IT773_RS12220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IT773_RS12255	COG1113	amino acid transport
IT773_RS12260	COG0778	Nitroreductase
IT773_RS12265	COG1012	belongs to the aldehyde dehydrogenase family
IT773_RS12275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IT773_RS12280	COG0531	amino acid
IT773_RS12285	COG0517	IMP dehydrogenase activity
IT773_RS12285	COG0516	GMP reductase activity
IT773_RS12305	COG0745	RESPONSE REGULATOR receiver
IT773_RS12310	COG5002	protein histidine kinase activity
IT773_RS12355	COG2246	polysaccharide biosynthetic process
IT773_RS12360	COG1940	carbohydrate kinase activity
IT773_RS12365	COG2244	polysaccharide biosynthetic process
IT773_RS12405	COG0492	ferredoxin-NADP+ reductase activity
IT773_RS12410	COG0640	Transcriptional regulator
IT773_RS12420	COG0012	GTP binding
IT773_RS12425	COG4481	Protein conserved in bacteria
IT773_RS12430	COG1475	DNA binding
IT773_RS12435	COG1192	Involved in chromosome partitioning
IT773_RS12440	COG0357	Ribosomal RNA small subunit methyltransferase G
IT773_RS12445	COG2153	protein acetylation
IT773_RS12470	COG3442	glutamine amidotransferase
IT773_RS12480	COG4684	Psort location CytoplasmicMembrane, score
IT773_RS12485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IT773_RS12500	COG0789	Transcriptional regulator
IT773_RS12515	COG0351	phosphomethylpyrimidine kinase
IT773_RS12530	COG1271	oxidase subunit
IT773_RS12535	COG1294	oxidase, subunit
IT773_RS12540	COG4988	ABC transporter
IT773_RS12545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IT773_RS12550	COG0142	geranyltranstransferase activity
IT773_RS12570	COG0463	Glycosyl transferase, family 2
IT773_RS12585	COG1252	NADH dehydrogenase
IT773_RS12595	COG0004	ammonium transporteR
IT773_RS12600	COG3158	transport of potassium into the cell
IT773_RS12605	COG1335	isochorismatase
IT773_RS12620	COG2267	carboxylic ester hydrolase activity
IT773_RS12630	COG0363	glucosamine-6-phosphate deaminase activity
IT773_RS12635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IT773_RS12645	COG0531	amino acid
IT773_RS12675	COG0698	ribose 5-phosphate isomerase
IT773_RS12690	COG0673	inositol 2-dehydrogenase activity
IT773_RS12700	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IT773_RS12705	COG1840	ABC-type Fe3 transport system, periplasmic component
IT773_RS12720	COG1176	ABC-type spermidine putrescine transport system, permease component I
IT773_RS12730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IT773_RS12735	COG0706	membrane insertase activity
IT773_RS12785	COG0577	efflux transmembrane transporter activity
IT773_RS12790	COG1136	(ABC) transporter
IT773_RS12875	COG2226	methyltransferase