locus-tag	class	description
Cop2CBH44_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Cop2CBH44_RS00025	COG1131	(ABC) transporter
Cop2CBH44_RS00030	COG1131	(ABC) transporter
Cop2CBH44_RS00035	COG0842	Transport permease protein
Cop2CBH44_RS00040	COG1129	ABC transporter
Cop2CBH44_RS00040	COG0842	Transport permease protein
Cop2CBH44_RS00045	COG3591	Belongs to the peptidase S1B family
Cop2CBH44_RS00050	COG0351	phosphomethylpyrimidine kinase
Cop2CBH44_RS00065	COG0352	thiamine-phosphate diphosphorylase activity
Cop2CBH44_RS00075	COG2022	thiamine diphosphate biosynthetic process
Cop2CBH44_RS00080	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Cop2CBH44_RS00085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Cop2CBH44_RS00090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Cop2CBH44_RS00095	COG1970	mechanosensitive ion channel activity
Cop2CBH44_RS00130	COG0534	Mate efflux family protein
Cop2CBH44_RS00145	COG0778	Nitroreductase
Cop2CBH44_RS00150	COG2205	protein histidine kinase activity
Cop2CBH44_RS00150	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS00150	COG3292	Two component regulator propeller
Cop2CBH44_RS00165	COG4771	TonB-dependent receptor
Cop2CBH44_RS00170	COG0702	epimerase
Cop2CBH44_RS00175	COG3119	arylsulfatase activity
Cop2CBH44_RS00180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS00185	COG3119	arylsulfatase activity
Cop2CBH44_RS00190	COG3250	beta-galactosidase activity
Cop2CBH44_RS00195	COG3250	beta-galactosidase activity
Cop2CBH44_RS00205	COG2205	protein histidine kinase activity
Cop2CBH44_RS00205	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS00205	COG2205	protein histidine kinase activity
Cop2CBH44_RS00205	COG3292	Two component regulator propeller
Cop2CBH44_RS00205	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS00205	COG3292	Two component regulator propeller
Cop2CBH44_RS00225	COG4771	TonB-dependent receptor
Cop2CBH44_RS00235	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS00245	COG3250	beta-galactosidase activity
Cop2CBH44_RS00250	COG3119	arylsulfatase activity
Cop2CBH44_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
Cop2CBH44_RS00280	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS00285	COG1640	4-alpha-glucanotransferase
Cop2CBH44_RS00295	COG4771	TonB-dependent receptor
Cop2CBH44_RS00300	COG0702	epimerase
Cop2CBH44_RS00320	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS00320	COG3292	Two component regulator propeller
Cop2CBH44_RS00320	COG2205	protein histidine kinase activity
Cop2CBH44_RS00335	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS00340	COG1979	alcohol dehydrogenase
Cop2CBH44_RS00345	COG1012	belongs to the aldehyde dehydrogenase family
Cop2CBH44_RS00370	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS00390	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Cop2CBH44_RS00400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Cop2CBH44_RS00405	COG2211	Major facilitator Superfamily
Cop2CBH44_RS00475	COG0656	L-ascorbic acid biosynthetic process
Cop2CBH44_RS00495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Cop2CBH44_RS00500	COG0656	L-ascorbic acid biosynthetic process
Cop2CBH44_RS00510	COG0667	Aldo Keto reductase
Cop2CBH44_RS00600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Cop2CBH44_RS00610	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS00620	COG0667	Aldo Keto reductase
Cop2CBH44_RS00650	COG4680	protein conserved in bacteria
Cop2CBH44_RS00655	COG2818	Glycosylase
Cop2CBH44_RS00670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Cop2CBH44_RS00680	COG1663	tetraacyldisaccharide 4'-kinase activity
Cop2CBH44_RS00685	COG0616	signal peptide processing
Cop2CBH44_RS00720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Cop2CBH44_RS00725	COG4804	nuclease activity
Cop2CBH44_RS00735	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Cop2CBH44_RS00810	COG3177	Filamentation induced by cAMP protein fic
Cop2CBH44_RS00905	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS00960	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS00965	COG1966	Carbon starvation protein
Cop2CBH44_RS00970	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Cop2CBH44_RS00975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Cop2CBH44_RS01015	COG3940	Belongs to the glycosyl hydrolase 43 family
Cop2CBH44_RS01025	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS01025	COG2205	protein histidine kinase activity
Cop2CBH44_RS01025	COG3292	Two component regulator propeller
Cop2CBH44_RS01035	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS01050	COG3408	Glycogen debranching enzyme
Cop2CBH44_RS01055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS01065	COG2382	esterase
Cop2CBH44_RS01070	COG1629	transport
Cop2CBH44_RS01080	COG4771	TonB-dependent receptor
Cop2CBH44_RS01110	COG1785	Belongs to the alkaline phosphatase family
Cop2CBH44_RS01150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Cop2CBH44_RS01175	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS01210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Cop2CBH44_RS01210	COG0551	DNA topoisomerase type I activity
Cop2CBH44_RS01240	COG0582	viral genome integration into host DNA
Cop2CBH44_RS01265	COG0784	Response regulator, receiver
Cop2CBH44_RS01265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Cop2CBH44_RS01265	COG2198	Histidine kinase
Cop2CBH44_RS01265	COG2205	protein histidine kinase activity
Cop2CBH44_RS01385	COG0358	DNA primase activity
Cop2CBH44_RS01475	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS01485	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS01490	COG5434	Belongs to the glycosyl hydrolase 28 family
Cop2CBH44_RS01495	COG0306	phosphate transporter
Cop2CBH44_RS01515	COG1629	transport
Cop2CBH44_RS01525	COG2755	lipolytic protein G-D-S-L family
Cop2CBH44_RS01525	COG0657	acetylesterase activity
Cop2CBH44_RS01535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS01575	COG2205	protein histidine kinase activity
Cop2CBH44_RS01575	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS01575	COG3292	Two component regulator propeller
Cop2CBH44_RS01585	COG4771	TonB-dependent receptor
Cop2CBH44_RS01605	COG4771	TonB-dependent receptor
Cop2CBH44_RS01645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Cop2CBH44_RS01650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Cop2CBH44_RS01655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Cop2CBH44_RS01660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Cop2CBH44_RS01680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Cop2CBH44_RS01690	COG0129	dihydroxy-acid dehydratase activity
Cop2CBH44_RS01695	COG0028	Belongs to the TPP enzyme family
Cop2CBH44_RS01710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Cop2CBH44_RS01725	COG0482	sulfurtransferase activity
Cop2CBH44_RS01730	COG3591	Belongs to the peptidase S1B family
Cop2CBH44_RS01765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Cop2CBH44_RS01765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Cop2CBH44_RS01770	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Cop2CBH44_RS01780	COG0347	Belongs to the P(II) protein family
Cop2CBH44_RS01785	COG0004	ammonium transporteR
Cop2CBH44_RS01810	COG0708	Exodeoxyribonuclease III
Cop2CBH44_RS01840	COG0588	phosphoglycerate mutase activity
Cop2CBH44_RS01845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Cop2CBH44_RS01855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Cop2CBH44_RS01860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Cop2CBH44_RS01875	COG0037	tRNA processing
Cop2CBH44_RS01890	COG0697	spore germination
Cop2CBH44_RS01900	COG3119	arylsulfatase activity
Cop2CBH44_RS01920	COG0656	L-ascorbic acid biosynthetic process
Cop2CBH44_RS01925	COG0583	DNA-binding transcription factor activity
Cop2CBH44_RS01930	COG0783	Belongs to the Dps family
Cop2CBH44_RS01955	COG0583	DNA-binding transcription factor activity
Cop2CBH44_RS01960	COG0724	RNA recognition motif
Cop2CBH44_RS01965	COG0544	peptidyl-prolyl cis-trans isomerase activity
Cop2CBH44_RS01975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Cop2CBH44_RS01995	COG0058	SHG alpha-glucan phosphorylase activity
Cop2CBH44_RS02000	COG0442	prolyl-tRNA aminoacylation
Cop2CBH44_RS02035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Cop2CBH44_RS02040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Cop2CBH44_RS02045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Cop2CBH44_RS02095	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS02095	COG2205	protein histidine kinase activity
Cop2CBH44_RS02095	COG3292	Two component regulator propeller
Cop2CBH44_RS02120	COG0457	Tetratricopeptide repeat
Cop2CBH44_RS02140	COG1629	transport
Cop2CBH44_RS02140	COG4206	TonB-dependent receptor
Cop2CBH44_RS02155	COG0702	epimerase
Cop2CBH44_RS02200	COG0588	phosphoglycerate mutase activity
Cop2CBH44_RS02220	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS02240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Cop2CBH44_RS02250	COG1668	transmembrane transport
Cop2CBH44_RS02255	COG4152	abc transporter atp-binding protein
Cop2CBH44_RS02260	COG0358	DNA primase activity
Cop2CBH44_RS02270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Cop2CBH44_RS02285	COG2311	Membrane
Cop2CBH44_RS02325	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS02350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Cop2CBH44_RS02355	COG0542	response to heat
Cop2CBH44_RS02360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Cop2CBH44_RS02380	COG3279	Response regulator of the LytR AlgR family
Cop2CBH44_RS02385	COG3275	phosphorelay sensor kinase activity
Cop2CBH44_RS02390	COG1136	(ABC) transporter
Cop2CBH44_RS02390	COG0577	efflux transmembrane transporter activity
Cop2CBH44_RS02395	COG1136	(ABC) transporter
Cop2CBH44_RS02435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Cop2CBH44_RS02440	COG0735	belongs to the Fur family
Cop2CBH44_RS02465	COG1285	pathogenesis
Cop2CBH44_RS02480	COG2814	Major facilitator Superfamily
Cop2CBH44_RS02495	COG1846	Transcriptional regulator
Cop2CBH44_RS02500	COG0360	Binds together with S18 to 16S ribosomal RNA
Cop2CBH44_RS02505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Cop2CBH44_RS02510	COG0359	binds to the 23S rRNA
Cop2CBH44_RS02535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Cop2CBH44_RS02545	COG0343	queuine tRNA-ribosyltransferase activity
Cop2CBH44_RS02555	COG0542	response to heat
Cop2CBH44_RS02560	COG4452	Inner membrane protein CreD
Cop2CBH44_RS02600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Cop2CBH44_RS02600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Cop2CBH44_RS02615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Cop2CBH44_RS02620	COG0534	Mate efflux family protein
Cop2CBH44_RS02640	COG0210	DNA helicase
Cop2CBH44_RS02675	COG0823	Involved in the tonB-independent uptake of proteins
Cop2CBH44_RS02675	COG1506	peptidase
Cop2CBH44_RS02680	COG1032	radical SAM domain protein
Cop2CBH44_RS02685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Cop2CBH44_RS02690	COG0556	nucleotide-excision repair
Cop2CBH44_RS02695	COG1983	PspC domain protein
Cop2CBH44_RS02700	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Cop2CBH44_RS02725	COG0864	Transcriptional regulator
Cop2CBH44_RS02730	COG4771	TonB-dependent receptor
Cop2CBH44_RS02740	COG0505	Belongs to the CarA family
Cop2CBH44_RS02745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Cop2CBH44_RS02750	COG0436	Aminotransferase
Cop2CBH44_RS02760	COG0067	glutamate synthase
Cop2CBH44_RS02760	COG0070	glutamate synthase
Cop2CBH44_RS02760	COG0069	glutamate synthase activity
Cop2CBH44_RS02775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Cop2CBH44_RS02785	COG0534	Mate efflux family protein
Cop2CBH44_RS02800	COG1538	Outer membrane efflux protein
Cop2CBH44_RS02815	COG0582	viral genome integration into host DNA
Cop2CBH44_RS02840	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Cop2CBH44_RS02850	COG0436	Aminotransferase
Cop2CBH44_RS02860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Cop2CBH44_RS02865	COG0367	asparagine synthase
Cop2CBH44_RS02900	COG0542	response to heat
Cop2CBH44_RS02910	COG0167	dihydroorotate dehydrogenase activity
Cop2CBH44_RS02915	COG0543	2 iron, 2 sulfur cluster binding
Cop2CBH44_RS02945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Cop2CBH44_RS02950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Cop2CBH44_RS02960	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS02990	COG2003	Belongs to the UPF0758 family
Cop2CBH44_RS03020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Cop2CBH44_RS03030	COG3279	Response regulator of the LytR AlgR family
Cop2CBH44_RS03035	COG3275	phosphorelay sensor kinase activity
Cop2CBH44_RS03040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Cop2CBH44_RS03060	COG3387	PFAM Glycoside hydrolase 15-related
Cop2CBH44_RS03075	COG1918	ferrous iron import across plasma membrane
Cop2CBH44_RS03075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Cop2CBH44_RS03095	COG0668	transmembrane transport
Cop2CBH44_RS03100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Cop2CBH44_RS03100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Cop2CBH44_RS03105	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Cop2CBH44_RS03110	COG0538	isocitrate dehydrogenase activity
Cop2CBH44_RS03115	COG0372	Belongs to the citrate synthase family
Cop2CBH44_RS03135	COG0514	ATP-dependent DNA helicase (RecQ)
Cop2CBH44_RS03140	COG1380	Effector of murein hydrolase LrgA
Cop2CBH44_RS03145	COG1346	cytolysis
Cop2CBH44_RS03160	COG0321	lipoyl(octanoyl) transferase activity
Cop2CBH44_RS03160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Cop2CBH44_RS03165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Cop2CBH44_RS03175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Cop2CBH44_RS03175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Cop2CBH44_RS03180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Cop2CBH44_RS03180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Cop2CBH44_RS03190	COG2830	Protein of unknown function (DUF452)
Cop2CBH44_RS03215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Cop2CBH44_RS03220	COG0602	queuosine metabolic process
Cop2CBH44_RS03235	COG1193	negative regulation of DNA recombination
Cop2CBH44_RS03250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Cop2CBH44_RS03255	COG0481	GTPase activity
Cop2CBH44_RS03260	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS03265	COG5002	protein histidine kinase activity
Cop2CBH44_RS03275	COG0318	PFAM AMP-dependent synthetase and ligase
Cop2CBH44_RS03280	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Cop2CBH44_RS03290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Cop2CBH44_RS03295	COG3250	beta-galactosidase activity
Cop2CBH44_RS03315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Cop2CBH44_RS03320	COG0375	protein maturation
Cop2CBH44_RS03325	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Cop2CBH44_RS03350	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Cop2CBH44_RS03355	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Cop2CBH44_RS03360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Cop2CBH44_RS03365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Cop2CBH44_RS03370	COG1252	NADH dehydrogenase
Cop2CBH44_RS03375	COG4677	pectinesterase activity
Cop2CBH44_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
Cop2CBH44_RS03385	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Cop2CBH44_RS03395	COG2264	protein methyltransferase activity
Cop2CBH44_RS03405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Cop2CBH44_RS03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Cop2CBH44_RS03445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Cop2CBH44_RS03450	COG0336	Belongs to the RNA methyltransferase TrmD family
Cop2CBH44_RS03455	COG0363	glucosamine-6-phosphate deaminase activity
Cop2CBH44_RS03460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Cop2CBH44_RS03470	COG3263	regulation of cellular component size
Cop2CBH44_RS03475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Cop2CBH44_RS03480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Cop2CBH44_RS03485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Cop2CBH44_RS03490	COG0284	orotidine-5'-phosphate decarboxylase activity
Cop2CBH44_RS03495	COG0126	phosphoglycerate kinase activity
Cop2CBH44_RS03515	COG2996	Protein conserved in bacteria
Cop2CBH44_RS03525	COG2249	NAD(P)H dehydrogenase (quinone) activity
Cop2CBH44_RS03540	COG1605	Chorismate mutase
Cop2CBH44_RS03540	COG0077	Prephenate dehydratase
Cop2CBH44_RS03545	COG0436	Aminotransferase
Cop2CBH44_RS03550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Cop2CBH44_RS03560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Cop2CBH44_RS03565	COG0569	domain protein
Cop2CBH44_RS03575	COG1674	ftsk spoiiie
Cop2CBH44_RS03585	COG0492	ferredoxin-NADP+ reductase activity
Cop2CBH44_RS03610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Cop2CBH44_RS03630	COG2205	protein histidine kinase activity
Cop2CBH44_RS03635	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS03645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Cop2CBH44_RS03675	COG0564	pseudouridine synthase activity
Cop2CBH44_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
Cop2CBH44_RS03690	COG1309	transcriptional regulator
Cop2CBH44_RS03710	COG0357	Ribosomal RNA small subunit methyltransferase G
Cop2CBH44_RS03715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Cop2CBH44_RS03735	COG0459	protein refolding
Cop2CBH44_RS03740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Cop2CBH44_RS03745	COG1082	Xylose isomerase domain protein TIM barrel
Cop2CBH44_RS03750	COG2131	deaminase
Cop2CBH44_RS03755	COG0793	Belongs to the peptidase S41A family
Cop2CBH44_RS03760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Cop2CBH44_RS03770	COG2197	response regulator
Cop2CBH44_RS03775	COG0612	Peptidase, M16
Cop2CBH44_RS03795	COG0463	Glycosyl transferase, family 2
Cop2CBH44_RS03815	COG1752	Esterase of the alpha-beta hydrolase superfamily
Cop2CBH44_RS03845	COG1858	cytochrome C peroxidase
Cop2CBH44_RS03850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Cop2CBH44_RS03855	COG1482	cell wall glycoprotein biosynthetic process
Cop2CBH44_RS03860	COG1649	PFAM Uncharacterised BCR, COG1649
Cop2CBH44_RS03885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Cop2CBH44_RS03910	COG0346	lactoylglutathione lyase activity
Cop2CBH44_RS03925	COG2130	NADP-dependent
Cop2CBH44_RS03930	COG0671	phosphoesterase, PA-phosphatase related
Cop2CBH44_RS03975	COG0714	Associated with various cellular activities
Cop2CBH44_RS03990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Cop2CBH44_RS03995	COG0583	DNA-binding transcription factor activity
Cop2CBH44_RS04000	COG2855	membrane
Cop2CBH44_RS04025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Cop2CBH44_RS04040	COG0791	NLP P60 protein
Cop2CBH44_RS04050	COG0237	dephospho-CoA kinase activity
Cop2CBH44_RS04060	COG1862	Preprotein translocase
Cop2CBH44_RS04065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Cop2CBH44_RS04075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Cop2CBH44_RS04080	COG1388	LysM domain
Cop2CBH44_RS04080	COG0741	lytic transglycosylase activity
Cop2CBH44_RS04090	COG3942	CHAP domain
Cop2CBH44_RS04090	COG1388	LysM domain
Cop2CBH44_RS04105	COG2076	Multidrug Resistance protein
Cop2CBH44_RS04140	COG1595	DNA-templated transcription, initiation
Cop2CBH44_RS04145	COG1592	Rubrerythrin
Cop2CBH44_RS04145	COG1773	rubredoxin
Cop2CBH44_RS04155	COG0019	diaminopimelate decarboxylase activity
Cop2CBH44_RS04160	COG0527	aspartate kinase activity
Cop2CBH44_RS04165	COG2884	Cell division ATP-binding protein ftsE
Cop2CBH44_RS04170	COG0140	phosphoribosyl-ATP diphosphatase activity
Cop2CBH44_RS04170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Cop2CBH44_RS04175	COG0107	imidazoleglycerol-phosphate synthase activity
Cop2CBH44_RS04180	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Cop2CBH44_RS04185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Cop2CBH44_RS04190	COG0788	formyltetrahydrofolate deformylase activity
Cop2CBH44_RS04195	COG1393	Belongs to the ArsC family
Cop2CBH44_RS04220	COG0110	maltose O-acetyltransferase activity
Cop2CBH44_RS04235	COG1063	alcohol dehydrogenase
Cop2CBH44_RS04255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Cop2CBH44_RS04275	COG3550	peptidyl-serine autophosphorylation
Cop2CBH44_RS04285	COG0537	adenosine 5'-monophosphoramidase activity
Cop2CBH44_RS04370	COG0653	protein targeting
Cop2CBH44_RS04405	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS04420	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Cop2CBH44_RS04430	COG2195	Cleaves the N-terminal amino acid of tripeptides
Cop2CBH44_RS04435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Cop2CBH44_RS04460	COG1595	DNA-templated transcription, initiation
Cop2CBH44_RS04465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Cop2CBH44_RS04470	COG2333	competence protein COMEC
Cop2CBH44_RS04470	COG0658	competence protein
Cop2CBH44_RS04485	COG0778	Nitroreductase
Cop2CBH44_RS04495	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Cop2CBH44_RS04500	COG0424	maF-like protein
Cop2CBH44_RS04505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Cop2CBH44_RS04515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Cop2CBH44_RS04530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Cop2CBH44_RS04535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Cop2CBH44_RS04555	COG1830	Aldolase
Cop2CBH44_RS04565	COG3119	arylsulfatase activity
Cop2CBH44_RS04575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Cop2CBH44_RS04605	COG3250	beta-galactosidase activity
Cop2CBH44_RS04610	COG3458	cephalosporin-C deacetylase activity
Cop2CBH44_RS04620	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Cop2CBH44_RS04625	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS04630	COG4948	Mandelate Racemase Muconate Lactonizing
Cop2CBH44_RS04660	COG4206	TonB-dependent receptor
Cop2CBH44_RS04660	COG1629	transport
Cop2CBH44_RS04670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Cop2CBH44_RS04675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Cop2CBH44_RS04690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Cop2CBH44_RS04705	COG0612	Peptidase, M16
Cop2CBH44_RS04720	COG4771	TonB-dependent receptor
Cop2CBH44_RS04725	COG2207	Transcriptional regulator
Cop2CBH44_RS04730	COG1070	Carbohydrate kinase
Cop2CBH44_RS04735	COG4806	L-rhamnose isomerase
Cop2CBH44_RS04745	COG0235	Class ii aldolase
Cop2CBH44_RS04750	COG2755	lipolytic protein G-D-S-L family
Cop2CBH44_RS04750	COG0657	acetylesterase activity
Cop2CBH44_RS04770	COG1773	rubredoxin
Cop2CBH44_RS04780	COG0490	domain, Protein
Cop2CBH44_RS04780	COG0471	metal ion transport
Cop2CBH44_RS04785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Cop2CBH44_RS04785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Cop2CBH44_RS04790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Cop2CBH44_RS04800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Cop2CBH44_RS04810	COG3956	TIGRFAM MazG family protein
Cop2CBH44_RS04830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Cop2CBH44_RS04835	COG1538	Outer membrane efflux protein
Cop2CBH44_RS04845	COG0281	malic enzyme
Cop2CBH44_RS04845	COG0280	phosphate acetyltransferase
Cop2CBH44_RS04850	COG1785	Belongs to the alkaline phosphatase family
Cop2CBH44_RS04855	COG3590	peptidase
Cop2CBH44_RS04860	COG0488	(ABC) transporter
Cop2CBH44_RS04885	COG0302	gtp cyclohydrolase
Cop2CBH44_RS04895	COG0149	triose-phosphate isomerase activity
Cop2CBH44_RS04910	COG2814	Major facilitator Superfamily
Cop2CBH44_RS04935	COG1245	4Fe-4S binding domain
Cop2CBH44_RS04935	COG2878	Part of a membrane complex involved in electron transport
Cop2CBH44_RS04940	COG4656	Part of a membrane complex involved in electron transport
Cop2CBH44_RS04945	COG4658	electron transport chain
Cop2CBH44_RS04950	COG4659	FMN binding
Cop2CBH44_RS04955	COG4660	Part of a membrane complex involved in electron transport
Cop2CBH44_RS04960	COG4657	Part of a membrane complex involved in electron transport
Cop2CBH44_RS04965	COG0784	Response regulator, receiver
Cop2CBH44_RS04965	COG2205	protein histidine kinase activity
Cop2CBH44_RS04995	COG2957	Belongs to the agmatine deiminase family
Cop2CBH44_RS05040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Cop2CBH44_RS05045	COG0574	Belongs to the PEP-utilizing enzyme family
Cop2CBH44_RS05045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Cop2CBH44_RS05060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Cop2CBH44_RS05095	COG0778	Nitroreductase
Cop2CBH44_RS05105	COG3408	Glycogen debranching enzyme
Cop2CBH44_RS05125	COG3118	belongs to the thioredoxin family
Cop2CBH44_RS05145	COG0285	dihydrofolate synthase activity
Cop2CBH44_RS05150	COG0251	oxidation-reduction process
Cop2CBH44_RS05155	COG0561	phosphatase activity
Cop2CBH44_RS05160	COG2311	Membrane
Cop2CBH44_RS05175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Cop2CBH44_RS05185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Cop2CBH44_RS05195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Cop2CBH44_RS05200	COG0517	IMP dehydrogenase activity
Cop2CBH44_RS05200	COG0516	GMP reductase activity
Cop2CBH44_RS05210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Cop2CBH44_RS05215	COG0740	serine-type endopeptidase activity
Cop2CBH44_RS05230	COG3290	protein histidine kinase activity
Cop2CBH44_RS05255	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS05275	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS05295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Cop2CBH44_RS05310	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Cop2CBH44_RS05325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Cop2CBH44_RS05330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Cop2CBH44_RS05335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Cop2CBH44_RS05340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Cop2CBH44_RS05345	COG0066	3-isopropylmalate dehydratase activity
Cop2CBH44_RS05355	COG0473	3-isopropylmalate dehydrogenase activity
Cop2CBH44_RS05375	COG4948	Mandelate Racemase Muconate Lactonizing
Cop2CBH44_RS05385	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Cop2CBH44_RS05390	COG0750	zinc metalloprotease
Cop2CBH44_RS05395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Cop2CBH44_RS05400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Cop2CBH44_RS05410	COG1629	transport
Cop2CBH44_RS05450	COG0716	FMN binding
Cop2CBH44_RS05455	COG0148	phosphopyruvate hydratase activity
Cop2CBH44_RS05465	COG1690	Belongs to the RtcB family
Cop2CBH44_RS05470	COG3541	Predicted nucleotidyltransferase
Cop2CBH44_RS05535	COG0629	single-stranded DNA binding
Cop2CBH44_RS05540	COG1192	Involved in chromosome partitioning
Cop2CBH44_RS05600	COG3118	belongs to the thioredoxin family
Cop2CBH44_RS05655	COG1373	ATPase (AAA superfamily
Cop2CBH44_RS05695	COG1705	Flagellar rod assembly protein muramidase FlgJ
Cop2CBH44_RS05700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Cop2CBH44_RS05760	COG0739	heme binding
Cop2CBH44_RS05810	COG0500	methyltransferase
Cop2CBH44_RS06000	COG0443	Heat shock 70 kDa protein
Cop2CBH44_RS06005	COG0346	lactoylglutathione lyase activity
Cop2CBH44_RS06010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Cop2CBH44_RS06020	COG4770	biotin carboxylase activity
Cop2CBH44_RS06025	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Cop2CBH44_RS06030	COG1309	transcriptional regulator
Cop2CBH44_RS06040	COG2375	cellular response to nickel ion
Cop2CBH44_RS06040	COG1132	(ABC) transporter
Cop2CBH44_RS06045	COG1132	(ABC) transporter
Cop2CBH44_RS06055	COG2217	Heavy metal translocating P-type atpase
Cop2CBH44_RS06075	COG0602	queuosine metabolic process
Cop2CBH44_RS06080	COG1328	CTP reductase activity
Cop2CBH44_RS06085	COG0778	Nitroreductase
Cop2CBH44_RS06090	COG2966	Psort location CytoplasmicMembrane, score
Cop2CBH44_RS06130	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Cop2CBH44_RS06135	COG1518	maintenance of DNA repeat elements
Cop2CBH44_RS06170	COG0564	pseudouridine synthase activity
Cop2CBH44_RS06180	COG2183	response to ionizing radiation
Cop2CBH44_RS06195	COG1408	metallophosphoesterase
Cop2CBH44_RS06200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Cop2CBH44_RS06200	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Cop2CBH44_RS06210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Cop2CBH44_RS06215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Cop2CBH44_RS06220	COG2198	Histidine kinase
Cop2CBH44_RS06220	COG5002	protein histidine kinase activity
Cop2CBH44_RS06220	COG0784	Response regulator, receiver
Cop2CBH44_RS06225	COG2204	response regulator
Cop2CBH44_RS06235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Cop2CBH44_RS06240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Cop2CBH44_RS06245	COG0513	Belongs to the DEAD box helicase family
Cop2CBH44_RS06255	COG0739	heme binding
Cop2CBH44_RS06260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Cop2CBH44_RS06265	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Cop2CBH44_RS06270	COG1702	phosphate starvation-inducible protein PhoH
Cop2CBH44_RS06275	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Cop2CBH44_RS06280	COG2226	methyltransferase
Cop2CBH44_RS06300	COG1629	transport
Cop2CBH44_RS06325	COG0339	signal peptide processing
Cop2CBH44_RS06340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Cop2CBH44_RS06340	COG0519	Catalyzes the synthesis of GMP from XMP
Cop2CBH44_RS06345	COG4651	solute:proton antiporter activity
Cop2CBH44_RS06345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Cop2CBH44_RS06350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Cop2CBH44_RS06365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Cop2CBH44_RS06375	COG0484	heat shock protein binding
Cop2CBH44_RS06380	COG0028	Belongs to the TPP enzyme family
Cop2CBH44_RS06385	COG0738	Major facilitator superfamily
Cop2CBH44_RS06395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Cop2CBH44_RS06400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Cop2CBH44_RS06410	COG1214	PFAM Peptidase M22, glycoprotease
Cop2CBH44_RS06420	COG0194	GDP metabolic process
Cop2CBH44_RS06425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Cop2CBH44_RS06470	COG0047	phosphoribosylformylglycinamidine synthase activity
Cop2CBH44_RS06470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Cop2CBH44_RS06475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Cop2CBH44_RS06480	COG2086	electron transfer activity
Cop2CBH44_RS06500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Cop2CBH44_RS06505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Cop2CBH44_RS06510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Cop2CBH44_RS06510	COG0731	radical SAM domain protein
Cop2CBH44_RS06545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Cop2CBH44_RS06550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Cop2CBH44_RS06555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Cop2CBH44_RS06560	COG1253	flavin adenine dinucleotide binding
Cop2CBH44_RS06590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Cop2CBH44_RS06590	COG0596	Alpha beta hydrolase
Cop2CBH44_RS06590	COG2226	methyltransferase
Cop2CBH44_RS06595	COG4413	Urea transporter
Cop2CBH44_RS06610	COG0525	valine-tRNA ligase activity
Cop2CBH44_RS06615	COG1649	PFAM Uncharacterised BCR, COG1649
Cop2CBH44_RS06620	COG3022	response to hydroperoxide
Cop2CBH44_RS06635	COG0586	Pfam SNARE associated Golgi protein
Cop2CBH44_RS06640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Cop2CBH44_RS06650	COG0439	Biotin carboxylase
Cop2CBH44_RS06670	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS06675	COG4771	TonB-dependent receptor
Cop2CBH44_RS06680	COG0702	epimerase
Cop2CBH44_RS06720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS06725	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS06725	COG2205	protein histidine kinase activity
Cop2CBH44_RS06725	COG3292	Two component regulator propeller
Cop2CBH44_RS06750	COG0702	epimerase
Cop2CBH44_RS06755	COG4771	TonB-dependent receptor
Cop2CBH44_RS06760	COG2721	sulfolactate sulfo-lyase activity
Cop2CBH44_RS06765	COG0488	(ABC) transporter
Cop2CBH44_RS06770	COG3250	beta-galactosidase activity
Cop2CBH44_RS06780	COG2954	triphosphatase activity
Cop2CBH44_RS06825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Cop2CBH44_RS06840	COG4206	TonB-dependent receptor
Cop2CBH44_RS06840	COG1629	transport
Cop2CBH44_RS06860	COG1404	Belongs to the peptidase S8 family
Cop2CBH44_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
Cop2CBH44_RS06875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Cop2CBH44_RS06905	COG0039	L-malate dehydrogenase activity
Cop2CBH44_RS06940	COG0702	epimerase
Cop2CBH44_RS06945	COG4771	TonB-dependent receptor
Cop2CBH44_RS06950	COG2205	protein histidine kinase activity
Cop2CBH44_RS06950	COG3292	Two component regulator propeller
Cop2CBH44_RS06950	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS06955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Cop2CBH44_RS06965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Cop2CBH44_RS06970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Cop2CBH44_RS06985	COG1904	glucuronate isomerase
Cop2CBH44_RS06990	COG1609	Transcriptional regulator
Cop2CBH44_RS06995	COG0246	Mannitol dehydrogenase
Cop2CBH44_RS07000	COG2721	sulfolactate sulfo-lyase activity
Cop2CBH44_RS07005	COG1760	l-serine dehydratase
Cop2CBH44_RS07015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Cop2CBH44_RS07020	COG0497	DNA recombination
Cop2CBH44_RS07035	COG2176	DNA-directed DNA polymerase activity
Cop2CBH44_RS07035	COG5002	protein histidine kinase activity
Cop2CBH44_RS07040	COG0592	DNA-directed DNA polymerase activity
Cop2CBH44_RS07050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Cop2CBH44_RS07055	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Cop2CBH44_RS07060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Cop2CBH44_RS07060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Cop2CBH44_RS07095	COG0488	(ABC) transporter
Cop2CBH44_RS07120	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Cop2CBH44_RS07125	COG1030	water channel activity
Cop2CBH44_RS07130	COG1595	DNA-templated transcription, initiation
Cop2CBH44_RS07135	COG0038	chloride channel
Cop2CBH44_RS07155	COG1127	ABC transporter
Cop2CBH44_RS07160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Cop2CBH44_RS07185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Cop2CBH44_RS07225	COG2003	Belongs to the UPF0758 family
Cop2CBH44_RS07270	COG1266	CAAX protease self-immunity
Cop2CBH44_RS07275	COG1575	Belongs to the MenA family. Type 1 subfamily
Cop2CBH44_RS07285	COG0307	riboflavin synthase, alpha
Cop2CBH44_RS07290	COG0778	Nitroreductase
Cop2CBH44_RS07295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Cop2CBH44_RS07320	COG0402	S-adenosylhomocysteine deaminase activity
Cop2CBH44_RS07335	COG0228	four-way junction DNA binding
Cop2CBH44_RS07385	COG2873	o-acetylhomoserine
Cop2CBH44_RS07410	COG1404	Belongs to the peptidase S8 family
Cop2CBH44_RS07425	COG1454	alcohol dehydrogenase
Cop2CBH44_RS07435	COG1070	Carbohydrate kinase
Cop2CBH44_RS07445	COG0738	Major facilitator superfamily
Cop2CBH44_RS07475	COG0582	viral genome integration into host DNA
Cop2CBH44_RS07525	COG2205	protein histidine kinase activity
Cop2CBH44_RS07525	COG2198	Histidine kinase
Cop2CBH44_RS07525	COG0784	Response regulator, receiver
Cop2CBH44_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Cop2CBH44_RS07540	COG4221	oxidoreductase activity
Cop2CBH44_RS07570	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS07595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Cop2CBH44_RS07610	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Cop2CBH44_RS07650	COG0366	Alpha amylase catalytic
Cop2CBH44_RS07655	COG0475	glutathione-regulated potassium exporter activity
Cop2CBH44_RS07660	COG4948	Mandelate Racemase Muconate Lactonizing
Cop2CBH44_RS07670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Cop2CBH44_RS07675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Cop2CBH44_RS07680	COG0463	Glycosyl transferase, family 2
Cop2CBH44_RS07685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Cop2CBH44_RS07690	COG1739	Uncharacterized protein family UPF0029
Cop2CBH44_RS07695	COG0534	Mate efflux family protein
Cop2CBH44_RS07700	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Cop2CBH44_RS07710	COG0297	glycogen (starch) synthase activity
Cop2CBH44_RS07725	COG1757	Na H antiporter
Cop2CBH44_RS07745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Cop2CBH44_RS07750	COG0131	Imidazoleglycerol-phosphate dehydratase
Cop2CBH44_RS07755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Cop2CBH44_RS07760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Cop2CBH44_RS07765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Cop2CBH44_RS07780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Cop2CBH44_RS07785	COG1169	isochorismate synthase
Cop2CBH44_RS07790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Cop2CBH44_RS07795	COG0552	protein localization to endoplasmic reticulum
Cop2CBH44_RS07800	COG1058	Belongs to the CinA family
Cop2CBH44_RS07800	COG1546	Belongs to the CinA family
Cop2CBH44_RS07805	COG0501	Belongs to the peptidase M48B family
Cop2CBH44_RS07810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Cop2CBH44_RS07820	COG1924	4 iron, 4 sulfur cluster binding
Cop2CBH44_RS07825	COG1309	transcriptional regulator
Cop2CBH44_RS07840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Cop2CBH44_RS07845	COG1011	Hydrolase
Cop2CBH44_RS07855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Cop2CBH44_RS07860	COG0726	polysaccharide deacetylase
Cop2CBH44_RS07885	COG0438	transferase activity, transferring glycosyl groups
Cop2CBH44_RS07895	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS07930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Cop2CBH44_RS07935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Cop2CBH44_RS07955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Cop2CBH44_RS07965	COG1136	(ABC) transporter
Cop2CBH44_RS07975	COG2247	cell wall binding repeat
Cop2CBH44_RS07975	COG2385	sporulation resulting in formation of a cellular spore
Cop2CBH44_RS07985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Cop2CBH44_RS07990	COG1215	transferase activity, transferring glycosyl groups
Cop2CBH44_RS08000	COG2211	Major facilitator Superfamily
Cop2CBH44_RS08005	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Cop2CBH44_RS08025	COG1629	transport
Cop2CBH44_RS08040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Cop2CBH44_RS08045	COG0006	proline dipeptidase activity
Cop2CBH44_RS08050	COG0617	tRNA 3'-terminal CCA addition
Cop2CBH44_RS08050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Cop2CBH44_RS08050	COG0517	IMP dehydrogenase activity
Cop2CBH44_RS08055	COG2095	MarC family integral membrane protein
Cop2CBH44_RS08070	COG1774	PSP1 C-terminal conserved region
Cop2CBH44_RS08075	COG1418	mRNA catabolic process
Cop2CBH44_RS08090	COG1523	belongs to the glycosyl hydrolase 13 family
Cop2CBH44_RS08105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Cop2CBH44_RS08115	COG1538	Outer membrane efflux protein
Cop2CBH44_RS08120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Cop2CBH44_RS08130	COG5492	domain, Protein
Cop2CBH44_RS08140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Cop2CBH44_RS08165	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Cop2CBH44_RS08175	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Cop2CBH44_RS08180	COG1805	sodium ion transport
Cop2CBH44_RS08185	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Cop2CBH44_RS08200	COG0632	four-way junction helicase activity
Cop2CBH44_RS08240	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS08255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Cop2CBH44_RS08275	COG2814	Major facilitator Superfamily
Cop2CBH44_RS08280	COG0805	protein transport
Cop2CBH44_RS08285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Cop2CBH44_RS08290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Cop2CBH44_RS08305	COG2204	response regulator
Cop2CBH44_RS08315	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Cop2CBH44_RS08320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Cop2CBH44_RS08325	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Cop2CBH44_RS08335	COG2205	protein histidine kinase activity
Cop2CBH44_RS08340	COG2205	protein histidine kinase activity
Cop2CBH44_RS08355	COG1082	Xylose isomerase domain protein TIM barrel
Cop2CBH44_RS08370	COG0561	phosphatase activity
Cop2CBH44_RS08375	COG4206	TonB-dependent receptor
Cop2CBH44_RS08375	COG1629	transport
Cop2CBH44_RS08415	COG0076	glutamate decarboxylase activity
Cop2CBH44_RS08420	COG2066	Belongs to the glutaminase family
Cop2CBH44_RS08430	COG0531	amino acid
Cop2CBH44_RS08435	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS08440	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS08455	COG3458	cephalosporin-C deacetylase activity
Cop2CBH44_RS08460	COG3459	Glycosyltransferase 36 associated
Cop2CBH44_RS08465	COG2211	Major facilitator Superfamily
Cop2CBH44_RS08470	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Cop2CBH44_RS08485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS08490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Cop2CBH44_RS08510	COG0702	epimerase
Cop2CBH44_RS08515	COG4771	TonB-dependent receptor
Cop2CBH44_RS08530	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Cop2CBH44_RS08535	COG2205	protein histidine kinase activity
Cop2CBH44_RS08535	COG3292	Two component regulator propeller
Cop2CBH44_RS08535	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS08550	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS08570	COG1940	carbohydrate kinase activity
Cop2CBH44_RS08575	COG0166	Belongs to the GPI family
Cop2CBH44_RS08580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Cop2CBH44_RS08585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Cop2CBH44_RS08590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Cop2CBH44_RS08595	COG1217	gtp-binding protein TYPA
Cop2CBH44_RS08605	COG2095	MarC family integral membrane protein
Cop2CBH44_RS08620	COG0438	transferase activity, transferring glycosyl groups
Cop2CBH44_RS08645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Cop2CBH44_RS08650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Cop2CBH44_RS08660	COG0839	Belongs to the complex I subunit 6 family
Cop2CBH44_RS08670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Cop2CBH44_RS08675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Cop2CBH44_RS08680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Cop2CBH44_RS08685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Cop2CBH44_RS08690	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Cop2CBH44_RS08695	COG0356	it plays a direct role in the translocation of protons across the membrane
Cop2CBH44_RS08700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Cop2CBH44_RS08710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Cop2CBH44_RS08715	COG0649	NAD binding
Cop2CBH44_RS08720	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Cop2CBH44_RS08725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Cop2CBH44_RS08735	COG1703	isobutyryl-CoA mutase activity
Cop2CBH44_RS08760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Cop2CBH44_RS08765	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Cop2CBH44_RS08780	COG3345	alpha-galactosidase
Cop2CBH44_RS08800	COG1242	4 iron, 4 sulfur cluster binding
Cop2CBH44_RS08805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Cop2CBH44_RS08810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Cop2CBH44_RS08825	COG1253	flavin adenine dinucleotide binding
Cop2CBH44_RS08830	COG0776	regulation of translation
Cop2CBH44_RS08835	COG1530	ribonuclease E activity
Cop2CBH44_RS08870	COG0811	peptide transport
Cop2CBH44_RS08895	COG0813	purine-nucleoside phosphorylase activity
Cop2CBH44_RS08900	COG0124	histidyl-tRNA synthetase
Cop2CBH44_RS08910	COG3119	arylsulfatase activity
Cop2CBH44_RS08920	COG0697	spore germination
Cop2CBH44_RS08940	COG0802	atpase or kinase
Cop2CBH44_RS08945	COG2204	response regulator
Cop2CBH44_RS08955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Cop2CBH44_RS08970	COG0084	hydrolase, TatD family'
Cop2CBH44_RS08990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Cop2CBH44_RS08995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Cop2CBH44_RS09000	COG0205	6-phosphofructokinase activity
Cop2CBH44_RS09010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Cop2CBH44_RS09015	COG1480	7TM receptor with intracellular HD hydrolase
Cop2CBH44_RS09020	COG2195	Cleaves the N-terminal amino acid of tripeptides
Cop2CBH44_RS09065	COG4771	TonB-dependent receptor
Cop2CBH44_RS09070	COG1595	DNA-templated transcription, initiation
Cop2CBH44_RS09090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Cop2CBH44_RS09100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Cop2CBH44_RS09105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Cop2CBH44_RS09110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Cop2CBH44_RS09125	COG2217	Heavy metal translocating P-type atpase
Cop2CBH44_RS09155	COG1166	arginine decarboxylase activity
Cop2CBH44_RS09160	COG0191	fructose-bisphosphate aldolase activity
Cop2CBH44_RS09165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Cop2CBH44_RS09170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Cop2CBH44_RS09200	COG0670	Belongs to the BI1 family
Cop2CBH44_RS09205	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Cop2CBH44_RS09210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Cop2CBH44_RS09220	COG0733	neurotransmitter:sodium symporter activity
Cop2CBH44_RS09230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Cop2CBH44_RS09230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Cop2CBH44_RS09275	COG0423	glycine-tRNA ligase activity
Cop2CBH44_RS09280	COG1704	LemA family
Cop2CBH44_RS09285	COG0545	Peptidyl-prolyl cis-trans isomerase
Cop2CBH44_RS09295	COG0534	Mate efflux family protein
Cop2CBH44_RS09300	COG0573	inorganic phosphate transmembrane transporter activity
Cop2CBH44_RS09305	COG0581	inorganic phosphate transmembrane transporter activity
Cop2CBH44_RS09310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Cop2CBH44_RS09370	COG0598	Magnesium transport protein CorA
Cop2CBH44_RS09375	COG2356	endonuclease I
Cop2CBH44_RS09380	COG2356	endonuclease I
Cop2CBH44_RS09400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Cop2CBH44_RS09410	COG2271	Major facilitator Superfamily
Cop2CBH44_RS09415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Cop2CBH44_RS09445	COG0564	pseudouridine synthase activity
Cop2CBH44_RS09450	COG1181	Belongs to the D-alanine--D-alanine ligase family
Cop2CBH44_RS09460	COG1940	carbohydrate kinase activity
Cop2CBH44_RS09465	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Cop2CBH44_RS09475	COG0719	Fe-S assembly protein
Cop2CBH44_RS09480	COG0396	ATPase activity
Cop2CBH44_RS09485	COG0719	Fe-S assembly protein
Cop2CBH44_RS09495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Cop2CBH44_RS09500	COG0195	Participates in both transcription termination and antitermination
Cop2CBH44_RS09505	COG0779	Required for maturation of 30S ribosomal subunits
Cop2CBH44_RS09515	COG1695	Transcriptional regulator
Cop2CBH44_RS09525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Cop2CBH44_RS09540	COG0811	peptide transport
Cop2CBH44_RS09545	COG0848	biopolymer transport protein
Cop2CBH44_RS09555	COG0456	acetyltransferase
Cop2CBH44_RS09560	COG0017	Asparaginyl-tRNA synthetase
Cop2CBH44_RS09565	COG1187	pseudouridine synthase activity
Cop2CBH44_RS09570	COG1047	Peptidyl-prolyl cis-trans
Cop2CBH44_RS09585	COG0739	heme binding
Cop2CBH44_RS09600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Cop2CBH44_RS09615	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS09625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Cop2CBH44_RS09630	COG0318	PFAM AMP-dependent synthetase and ligase
Cop2CBH44_RS09640	COG1160	GTP binding
Cop2CBH44_RS09645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Cop2CBH44_RS09650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Cop2CBH44_RS09670	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Cop2CBH44_RS09675	COG0052	Belongs to the universal ribosomal protein uS2 family
Cop2CBH44_RS09680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cop2CBH44_RS09685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Cop2CBH44_RS09720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Cop2CBH44_RS09730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Cop2CBH44_RS09755	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS09765	COG0489	protein tyrosine kinase activity
Cop2CBH44_RS09780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Cop2CBH44_RS09800	COG1475	DNA binding
Cop2CBH44_RS09805	COG1192	Involved in chromosome partitioning
Cop2CBH44_RS09810	COG4948	Mandelate Racemase Muconate Lactonizing
Cop2CBH44_RS09815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Cop2CBH44_RS09825	COG1438	arginine binding
Cop2CBH44_RS09835	COG0137	argininosuccinate synthase activity
Cop2CBH44_RS09840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Cop2CBH44_RS09845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Cop2CBH44_RS09850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Cop2CBH44_RS09855	COG0629	single-stranded DNA binding
Cop2CBH44_RS09905	COG0799	negative regulation of ribosome biogenesis
Cop2CBH44_RS09910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Cop2CBH44_RS09915	COG4589	Belongs to the CDS family
Cop2CBH44_RS09920	COG0488	(ABC) transporter
Cop2CBH44_RS09925	COG4770	biotin carboxylase activity
Cop2CBH44_RS09930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Cop2CBH44_RS09935	COG0242	peptide deformylase activity
Cop2CBH44_RS09940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Cop2CBH44_RS09950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Cop2CBH44_RS10180	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS10200	COG0551	DNA topoisomerase type I activity
Cop2CBH44_RS10200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Cop2CBH44_RS10215	COG4804	nuclease activity
Cop2CBH44_RS10240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Cop2CBH44_RS10245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Cop2CBH44_RS10275	COG3420	alginic acid biosynthetic process
Cop2CBH44_RS10290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Cop2CBH44_RS10295	COG0009	L-threonylcarbamoyladenylate synthase
Cop2CBH44_RS10305	COG1312	Catalyzes the dehydration of D-mannonate
Cop2CBH44_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
Cop2CBH44_RS10315	COG1609	Transcriptional regulator
Cop2CBH44_RS10320	COG0546	phosphoglycolate phosphatase activity
Cop2CBH44_RS10335	COG0367	asparagine synthase
Cop2CBH44_RS10385	COG0148	phosphopyruvate hydratase activity
Cop2CBH44_RS10395	COG0203	ribosomal protein L17
Cop2CBH44_RS10400	COG0202	RNA polymerase activity
Cop2CBH44_RS10405	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Cop2CBH44_RS10410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Cop2CBH44_RS10415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Cop2CBH44_RS10420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Cop2CBH44_RS10425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Cop2CBH44_RS10430	COG0024	Methionine aminopeptidase
Cop2CBH44_RS10440	COG0200	Binds to the 23S rRNA
Cop2CBH44_RS10445	COG1841	ribosomal large subunit assembly
Cop2CBH44_RS10450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Cop2CBH44_RS10455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Cop2CBH44_RS10460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Cop2CBH44_RS10465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Cop2CBH44_RS10470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Cop2CBH44_RS10475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Cop2CBH44_RS10480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Cop2CBH44_RS10485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Cop2CBH44_RS10490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Cop2CBH44_RS10495	COG0255	Belongs to the universal ribosomal protein uL29 family
Cop2CBH44_RS10500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Cop2CBH44_RS10505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Cop2CBH44_RS10510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Cop2CBH44_RS10515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Cop2CBH44_RS10520	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Cop2CBH44_RS10525	COG0089	rRNA binding
Cop2CBH44_RS10530	COG0088	Forms part of the polypeptide exit tunnel
Cop2CBH44_RS10535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Cop2CBH44_RS10540	COG0051	transcription antitermination factor activity, RNA binding
Cop2CBH44_RS10545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Cop2CBH44_RS10550	COG0049	tRNA binding
Cop2CBH44_RS10555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Cop2CBH44_RS10565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Cop2CBH44_RS10575	COG3104	oligopeptide transport
Cop2CBH44_RS10585	COG2234	aminopeptidase activity
Cop2CBH44_RS10590	COG1619	proteins homologs of microcin C7 resistance protein MccF
Cop2CBH44_RS10595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Cop2CBH44_RS10600	COG0589	response to stress
Cop2CBH44_RS10600	COG0475	glutathione-regulated potassium exporter activity
Cop2CBH44_RS10645	COG0358	DNA primase activity
Cop2CBH44_RS10680	COG0561	phosphatase activity
Cop2CBH44_RS10690	COG1629	transport
Cop2CBH44_RS10700	COG4771	TonB-dependent receptor
Cop2CBH44_RS10705	COG0702	epimerase
Cop2CBH44_RS10720	COG3250	beta-galactosidase activity
Cop2CBH44_RS10740	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS10780	COG1741	Belongs to the pirin family
Cop2CBH44_RS10790	COG2194	sulfuric ester hydrolase activity
Cop2CBH44_RS10795	COG1185	polyribonucleotide nucleotidyltransferase activity
Cop2CBH44_RS10805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Cop2CBH44_RS10810	COG3292	Two component regulator propeller
Cop2CBH44_RS10810	COG2205	protein histidine kinase activity
Cop2CBH44_RS10810	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS10810	COG3292	Two component regulator propeller
Cop2CBH44_RS10810	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS10810	COG2205	protein histidine kinase activity
Cop2CBH44_RS10815	COG5492	domain, Protein
Cop2CBH44_RS10820	COG3119	arylsulfatase activity
Cop2CBH44_RS10825	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS10840	COG4771	TonB-dependent receptor
Cop2CBH44_RS10845	COG0702	epimerase
Cop2CBH44_RS10855	COG1368	sulfuric ester hydrolase activity
Cop2CBH44_RS10865	COG4591	ABC-type transport system involved in lipoprotein release permease component
Cop2CBH44_RS10870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Cop2CBH44_RS10885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Cop2CBH44_RS10890	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS10905	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Cop2CBH44_RS10925	COG0482	sulfurtransferase activity
Cop2CBH44_RS10935	COG0612	Peptidase, M16
Cop2CBH44_RS10980	COG0513	Belongs to the DEAD box helicase family
Cop2CBH44_RS10990	COG1785	Belongs to the alkaline phosphatase family
Cop2CBH44_RS11025	COG1083	cytidylyl-transferase
Cop2CBH44_RS11030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Cop2CBH44_RS11035	COG2089	acid synthase
Cop2CBH44_RS11050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Cop2CBH44_RS11055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Cop2CBH44_RS11080	COG1215	transferase activity, transferring glycosyl groups
Cop2CBH44_RS11090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Cop2CBH44_RS11095	COG0700	Nucleoside recognition
Cop2CBH44_RS11100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Cop2CBH44_RS11105	COG0445	tRNA wobble uridine modification
Cop2CBH44_RS11110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Cop2CBH44_RS11115	COG0322	excinuclease ABC activity
Cop2CBH44_RS11120	COG1490	D-aminoacyl-tRNA deacylase activity
Cop2CBH44_RS11125	COG1694	Mazg nucleotide pyrophosphohydrolase
Cop2CBH44_RS11130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Cop2CBH44_RS11135	COG0142	geranyltranstransferase activity
Cop2CBH44_RS11140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Cop2CBH44_RS11140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Cop2CBH44_RS11145	COG0363	glucosamine-6-phosphate deaminase activity
Cop2CBH44_RS11150	COG0363	glucosamine-6-phosphate deaminase activity
Cop2CBH44_RS11165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Cop2CBH44_RS11170	COG0793	Belongs to the peptidase S41A family
Cop2CBH44_RS11180	COG0668	transmembrane transport
Cop2CBH44_RS11185	COG2814	Major facilitator Superfamily
Cop2CBH44_RS11190	COG0012	GTP binding
Cop2CBH44_RS11205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Cop2CBH44_RS11210	COG1592	Rubrerythrin
Cop2CBH44_RS11225	COG4771	TonB-dependent receptor
Cop2CBH44_RS11260	COG2223	nitrite transmembrane transporter activity
Cop2CBH44_RS11270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Cop2CBH44_RS11275	COG0681	Belongs to the peptidase S26 family
Cop2CBH44_RS11275	COG0681	Belongs to the peptidase S26 family
Cop2CBH44_RS11280	COG0681	Belongs to the peptidase S26 family
Cop2CBH44_RS11290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Cop2CBH44_RS11290	COG3153	acetyltransferase
Cop2CBH44_RS11295	COG1045	serine acetyltransferase
Cop2CBH44_RS11300	COG0116	Belongs to the methyltransferase superfamily
Cop2CBH44_RS11305	COG0823	Involved in the tonB-independent uptake of proteins
Cop2CBH44_RS11305	COG1506	peptidase
Cop2CBH44_RS11315	COG1238	metal cluster binding
Cop2CBH44_RS11320	COG0606	chelatase, subunit chli
Cop2CBH44_RS11330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Cop2CBH44_RS11335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Cop2CBH44_RS11335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Cop2CBH44_RS11340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Cop2CBH44_RS11345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Cop2CBH44_RS11350	COG1968	undecaprenyl-diphosphatase activity
Cop2CBH44_RS11360	COG2177	Part of the ABC transporter FtsEX involved in
Cop2CBH44_RS11365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Cop2CBH44_RS11375	COG0427	acetyl-CoA hydrolase
Cop2CBH44_RS11380	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Cop2CBH44_RS11380	COG0731	radical SAM domain protein
Cop2CBH44_RS11395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Cop2CBH44_RS11415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Cop2CBH44_RS11420	COG0495	leucyl-tRNA aminoacylation
Cop2CBH44_RS11425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Cop2CBH44_RS11435	COG3292	Two component regulator propeller
Cop2CBH44_RS11435	COG2205	protein histidine kinase activity
Cop2CBH44_RS11435	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS11445	COG4771	TonB-dependent receptor
Cop2CBH44_RS11450	COG4771	TonB-dependent receptor
Cop2CBH44_RS11455	COG0702	epimerase
Cop2CBH44_RS11470	COG5652	VanZ like family
Cop2CBH44_RS11475	COG5652	VanZ like family
Cop2CBH44_RS11480	COG3250	beta-galactosidase activity
Cop2CBH44_RS11495	COG3119	arylsulfatase activity
Cop2CBH44_RS11505	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS11510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Cop2CBH44_RS11515	COG1053	succinate dehydrogenase
Cop2CBH44_RS11530	COG0784	Response regulator, receiver
Cop2CBH44_RS11530	COG2205	protein histidine kinase activity
Cop2CBH44_RS11535	COG2205	protein histidine kinase activity
Cop2CBH44_RS11535	COG3292	Two component regulator propeller
Cop2CBH44_RS11535	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS11560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Cop2CBH44_RS11560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Cop2CBH44_RS11610	COG2885	chlorophyll binding
Cop2CBH44_RS11625	COG3507	Belongs to the glycosyl hydrolase 43 family
Cop2CBH44_RS11630	COG5434	Belongs to the glycosyl hydrolase 28 family
Cop2CBH44_RS11645	COG5434	Belongs to the glycosyl hydrolase 28 family
Cop2CBH44_RS11660	COG0702	epimerase
Cop2CBH44_RS11665	COG1629	transport
Cop2CBH44_RS11675	COG4771	TonB-dependent receptor
Cop2CBH44_RS11680	COG5434	Belongs to the glycosyl hydrolase 28 family
Cop2CBH44_RS11685	COG3345	alpha-galactosidase
Cop2CBH44_RS11690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Cop2CBH44_RS11695	COG0084	hydrolase, TatD family'
Cop2CBH44_RS11700	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Cop2CBH44_RS11705	COG0594	ribonuclease P activity
Cop2CBH44_RS11720	COG1611	Belongs to the LOG family
Cop2CBH44_RS11725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Cop2CBH44_RS11740	COG0726	polysaccharide deacetylase
Cop2CBH44_RS11745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Cop2CBH44_RS11750	COG0018	arginyl-trna synthetase
Cop2CBH44_RS11755	COG0659	secondary active sulfate transmembrane transporter activity
Cop2CBH44_RS11765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Cop2CBH44_RS11770	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Cop2CBH44_RS11780	COG0826	peptidase U32
Cop2CBH44_RS11785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Cop2CBH44_RS11810	COG0793	Belongs to the peptidase S41A family
Cop2CBH44_RS11815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Cop2CBH44_RS11825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Cop2CBH44_RS11830	COG0557	exoribonuclease II activity
Cop2CBH44_RS11835	COG0187	DNA topoisomerase II activity
Cop2CBH44_RS11845	COG0268	Binds directly to 16S ribosomal RNA
Cop2CBH44_RS11855	COG1381	Involved in DNA repair and RecF pathway recombination
Cop2CBH44_RS11865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Cop2CBH44_RS11890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Cop2CBH44_RS11895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Cop2CBH44_RS11905	COG0215	cysteine-tRNA ligase activity
Cop2CBH44_RS11925	COG1136	(ABC) transporter
Cop2CBH44_RS11930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Cop2CBH44_RS11935	COG0657	acetylesterase activity
Cop2CBH44_RS11945	COG0493	'glutamate synthase
Cop2CBH44_RS11950	COG0543	2 iron, 2 sulfur cluster binding
Cop2CBH44_RS11965	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS11970	COG4804	nuclease activity
Cop2CBH44_RS12025	COG0662	Cupin 2, conserved barrel domain protein
Cop2CBH44_RS12025	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Cop2CBH44_RS12040	COG2255	four-way junction helicase activity
Cop2CBH44_RS12050	COG0859	PFAM glycosyl transferase family 9
Cop2CBH44_RS12070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Cop2CBH44_RS12075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Cop2CBH44_RS12080	COG0571	ribonuclease III activity
Cop2CBH44_RS12090	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS12095	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS12105	COG1442	glycosyl transferase family 8
Cop2CBH44_RS12105	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS12110	COG0438	transferase activity, transferring glycosyl groups
Cop2CBH44_RS12120	COG0328	RNA-DNA hybrid ribonuclease activity
Cop2CBH44_RS12120	COG3341	Caulimovirus viroplasmin
Cop2CBH44_RS12125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Cop2CBH44_RS12130	COG0686	Belongs to the AlaDH PNT family
Cop2CBH44_RS12140	COG0674	pyruvate-flavodoxin oxidoreductase activity
Cop2CBH44_RS12140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Cop2CBH44_RS12145	COG1013	pyruvate-flavodoxin oxidoreductase activity
Cop2CBH44_RS12155	COG1011	Hydrolase
Cop2CBH44_RS12160	COG0346	lactoylglutathione lyase activity
Cop2CBH44_RS12165	COG2382	esterase
Cop2CBH44_RS12180	COG2096	Adenosyltransferase
Cop2CBH44_RS12200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Cop2CBH44_RS12220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Cop2CBH44_RS12225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Cop2CBH44_RS12230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Cop2CBH44_RS12240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Cop2CBH44_RS12245	COG2113	Glycine betaine
Cop2CBH44_RS12250	COG4176	ABC-type proline glycine betaine transport system permease component
Cop2CBH44_RS12270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Cop2CBH44_RS12285	COG0196	riboflavin kinase activity
Cop2CBH44_RS12290	COG1522	sequence-specific DNA binding
Cop2CBH44_RS12300	COG0545	Peptidyl-prolyl cis-trans isomerase
Cop2CBH44_RS12305	COG0545	Peptidyl-prolyl cis-trans isomerase
Cop2CBH44_RS12310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Cop2CBH44_RS12315	COG1283	sodium-dependent phosphate transmembrane transporter activity
Cop2CBH44_RS12320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Cop2CBH44_RS12325	COG1011	Hydrolase
Cop2CBH44_RS12345	COG4409	exo-alpha-(2->6)-sialidase activity
Cop2CBH44_RS12350	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS12355	COG0737	Belongs to the 5'-nucleotidase family
Cop2CBH44_RS12360	COG0737	Belongs to the 5'-nucleotidase family
Cop2CBH44_RS12365	COG0335	large ribosomal subunit rRNA binding
Cop2CBH44_RS12375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Cop2CBH44_RS12385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Cop2CBH44_RS12390	COG1610	YqeY-like protein
Cop2CBH44_RS12395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Cop2CBH44_RS12410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Cop2CBH44_RS12415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Cop2CBH44_RS12420	COG0772	Belongs to the SEDS family
Cop2CBH44_RS12425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Cop2CBH44_RS12430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Cop2CBH44_RS12435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Cop2CBH44_RS12440	COG0768	penicillin binding
Cop2CBH44_RS12450	COG0275	rRNA processing
Cop2CBH44_RS12485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Cop2CBH44_RS12495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Cop2CBH44_RS12515	COG0482	sulfurtransferase activity
Cop2CBH44_RS12520	COG1404	Belongs to the peptidase S8 family
Cop2CBH44_RS12525	COG1570	exodeoxyribonuclease VII activity
Cop2CBH44_RS12530	COG1722	exodeoxyribonuclease VII activity
Cop2CBH44_RS12535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Cop2CBH44_RS12555	COG2207	Transcriptional regulator
Cop2CBH44_RS12560	COG0280	phosphate acetyltransferase
Cop2CBH44_RS12565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Cop2CBH44_RS12570	COG0598	Magnesium transport protein CorA
Cop2CBH44_RS12580	COG2151	metal-sulfur cluster biosynthetic enzyme
Cop2CBH44_RS12595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Cop2CBH44_RS12605	COG0039	L-malate dehydrogenase activity
Cop2CBH44_RS12610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Cop2CBH44_RS12625	COG0179	Fumarylacetoacetate (FAA) hydrolase
Cop2CBH44_RS12630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Cop2CBH44_RS12640	COG1074	ATP-dependent DNA helicase activity
Cop2CBH44_RS12645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Cop2CBH44_RS12650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Cop2CBH44_RS12655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Cop2CBH44_RS12665	COG0463	Glycosyl transferase, family 2
Cop2CBH44_RS12665	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS12670	COG2003	Belongs to the UPF0758 family
Cop2CBH44_RS12680	COG2252	PERMEase
Cop2CBH44_RS12685	COG0628	permease
Cop2CBH44_RS12700	COG2304	oxidoreductase activity
Cop2CBH44_RS12715	COG0159	tryptophan synthase activity
Cop2CBH44_RS12720	COG0135	phosphoribosylanthranilate isomerase activity
Cop2CBH44_RS12725	COG0134	indole-3-glycerol-phosphate synthase activity
Cop2CBH44_RS12740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Cop2CBH44_RS12745	COG0133	tryptophan synthase activity
Cop2CBH44_RS12755	COG2205	protein histidine kinase activity
Cop2CBH44_RS12755	COG0784	Response regulator, receiver
Cop2CBH44_RS12780	COG0667	Aldo Keto reductase
Cop2CBH44_RS12785	COG0165	Argininosuccinate lyase
Cop2CBH44_RS12795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Cop2CBH44_RS12800	COG1040	competence protein
Cop2CBH44_RS12805	COG2137	regulation of response to DNA damage stimulus
Cop2CBH44_RS12810	COG2890	protein-(glutamine-N5) methyltransferase activity
Cop2CBH44_RS12815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Cop2CBH44_RS12815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Cop2CBH44_RS12830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Cop2CBH44_RS12835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Cop2CBH44_RS12850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Cop2CBH44_RS12855	COG1187	pseudouridine synthase activity
Cop2CBH44_RS12860	COG3250	beta-galactosidase activity
Cop2CBH44_RS12875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS12880	COG3292	Two component regulator propeller
Cop2CBH44_RS12880	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS12880	COG2205	protein histidine kinase activity
Cop2CBH44_RS12895	COG4771	TonB-dependent receptor
Cop2CBH44_RS12900	COG0702	epimerase
Cop2CBH44_RS12905	COG5492	domain, Protein
Cop2CBH44_RS12930	COG3408	Glycogen debranching enzyme
Cop2CBH44_RS12930	COG3119	arylsulfatase activity
Cop2CBH44_RS12940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Cop2CBH44_RS12945	COG0006	proline dipeptidase activity
Cop2CBH44_RS12950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Cop2CBH44_RS12955	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS12985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Cop2CBH44_RS13005	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Cop2CBH44_RS13010	COG0081	regulation of translation
Cop2CBH44_RS13015	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Cop2CBH44_RS13020	COG0222	ribosome binding
Cop2CBH44_RS13025	COG0085	RNA polymerase activity
Cop2CBH44_RS13030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Cop2CBH44_RS13045	COG1914	H( )-stimulated, divalent metal cation uptake system
Cop2CBH44_RS13050	COG0534	Mate efflux family protein
Cop2CBH44_RS13055	COG0180	Tryptophanyl-tRNA synthetase
Cop2CBH44_RS13065	COG1522	sequence-specific DNA binding
Cop2CBH44_RS13075	COG1473	amidohydrolase
Cop2CBH44_RS13085	COG1121	(ABC) transporter
Cop2CBH44_RS13090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Cop2CBH44_RS13090	COG0758	DNA mediated transformation
Cop2CBH44_RS13105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Cop2CBH44_RS13110	COG3022	response to hydroperoxide
Cop2CBH44_RS13115	COG5492	domain, Protein
Cop2CBH44_RS13120	COG0318	PFAM AMP-dependent synthetase and ligase
Cop2CBH44_RS13155	COG0756	dUTP diphosphatase activity
Cop2CBH44_RS13200	COG1215	transferase activity, transferring glycosyl groups
Cop2CBH44_RS13205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Cop2CBH44_RS13215	COG1022	Amp-dependent synthetase and ligase
Cop2CBH44_RS13225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Cop2CBH44_RS13235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Cop2CBH44_RS13240	COG3104	oligopeptide transport
Cop2CBH44_RS13250	COG0563	adenylate kinase activity
Cop2CBH44_RS13255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Cop2CBH44_RS13260	COG1496	oxidoreductase activity
Cop2CBH44_RS13270	COG0295	cytidine deaminase activity
Cop2CBH44_RS13275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Cop2CBH44_RS13285	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Cop2CBH44_RS13290	COG1120	ATPase activity
Cop2CBH44_RS13305	COG2197	response regulator
Cop2CBH44_RS13315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Cop2CBH44_RS13320	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Cop2CBH44_RS13325	COG0460	homoserine dehydrogenase
Cop2CBH44_RS13325	COG0527	aspartate kinase activity
Cop2CBH44_RS13335	COG0252	asparaginase activity
Cop2CBH44_RS13345	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Cop2CBH44_RS13350	COG1629	transport
Cop2CBH44_RS13350	COG4206	TonB-dependent receptor
Cop2CBH44_RS13355	COG3681	Belongs to the UPF0597 family
Cop2CBH44_RS13365	COG1132	(ABC) transporter
Cop2CBH44_RS13375	COG0641	radical SAM
Cop2CBH44_RS13380	COG1971	Probably functions as a manganese efflux pump
Cop2CBH44_RS13385	COG1477	protein flavinylation
Cop2CBH44_RS13390	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Cop2CBH44_RS13405	COG0436	Aminotransferase
Cop2CBH44_RS13415	COG1595	DNA-templated transcription, initiation
Cop2CBH44_RS13425	COG2205	protein histidine kinase activity
Cop2CBH44_RS13430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Cop2CBH44_RS13430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Cop2CBH44_RS13455	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS13475	COG1472	Belongs to the glycosyl hydrolase 3 family
Cop2CBH44_RS13480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS13520	COG0668	transmembrane transport
Cop2CBH44_RS13535	COG0653	protein targeting
Cop2CBH44_RS13545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Cop2CBH44_RS13555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Cop2CBH44_RS13560	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Cop2CBH44_RS13610	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS13635	COG3345	alpha-galactosidase
Cop2CBH44_RS13650	COG1629	transport
Cop2CBH44_RS13650	COG4206	TonB-dependent receptor
Cop2CBH44_RS13660	COG4771	TonB-dependent receptor
Cop2CBH44_RS13675	COG3940	Belongs to the glycosyl hydrolase 43 family
Cop2CBH44_RS13680	COG3119	arylsulfatase activity
Cop2CBH44_RS13695	COG4771	TonB-dependent receptor
Cop2CBH44_RS13700	COG0702	epimerase
Cop2CBH44_RS13735	COG0024	Methionine aminopeptidase
Cop2CBH44_RS13780	COG2239	Acts as a magnesium transporter
Cop2CBH44_RS13785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Cop2CBH44_RS13795	COG2195	Cleaves the N-terminal amino acid of tripeptides
Cop2CBH44_RS13805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Cop2CBH44_RS13820	COG0702	epimerase
Cop2CBH44_RS13825	COG4771	TonB-dependent receptor
Cop2CBH44_RS13855	COG1940	carbohydrate kinase activity
Cop2CBH44_RS13865	COG3119	arylsulfatase activity
Cop2CBH44_RS13870	COG5492	domain, Protein
Cop2CBH44_RS13880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS13885	COG2205	protein histidine kinase activity
Cop2CBH44_RS13885	COG3292	Two component regulator propeller
Cop2CBH44_RS13885	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS13895	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Cop2CBH44_RS13900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Cop2CBH44_RS13900	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Cop2CBH44_RS13905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Cop2CBH44_RS13910	COG0156	8-amino-7-oxononanoate synthase activity
Cop2CBH44_RS13950	COG1131	(ABC) transporter
Cop2CBH44_RS13970	COG1629	transport
Cop2CBH44_RS14000	COG0037	tRNA processing
Cop2CBH44_RS14020	COG4864	UPF0365 protein
Cop2CBH44_RS14025	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Cop2CBH44_RS14030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Cop2CBH44_RS14045	COG2211	Major facilitator Superfamily
Cop2CBH44_RS14050	COG2942	2-epimerase
Cop2CBH44_RS14060	COG3292	Two component regulator propeller
Cop2CBH44_RS14060	COG2205	protein histidine kinase activity
Cop2CBH44_RS14060	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS14065	COG4771	TonB-dependent receptor
Cop2CBH44_RS14070	COG0702	epimerase
Cop2CBH44_RS14085	COG3940	Belongs to the glycosyl hydrolase 43 family
Cop2CBH44_RS14105	COG0438	transferase activity, transferring glycosyl groups
Cop2CBH44_RS14105	COG0297	glycogen (starch) synthase activity
Cop2CBH44_RS14115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Cop2CBH44_RS14135	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS14170	COG1215	transferase activity, transferring glycosyl groups
Cop2CBH44_RS14175	COG0071	Belongs to the small heat shock protein (HSP20) family
Cop2CBH44_RS14185	COG3876	Protein conserved in bacteria
Cop2CBH44_RS14190	COG2502	aspartate--ammonia ligase
Cop2CBH44_RS14205	COG0657	acetylesterase activity
Cop2CBH44_RS14205	COG2755	lipolytic protein G-D-S-L family
Cop2CBH44_RS14210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Cop2CBH44_RS14215	COG0572	uridine kinase
Cop2CBH44_RS14225	COG1752	Esterase of the alpha-beta hydrolase superfamily
Cop2CBH44_RS14235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Cop2CBH44_RS14240	COG0488	(ABC) transporter
Cop2CBH44_RS14255	COG2895	sulfate adenylyltransferase (ATP) activity
Cop2CBH44_RS14260	COG0175	sulfate reduction
Cop2CBH44_RS14265	COG0529	Catalyzes the synthesis of activated sulfate
Cop2CBH44_RS14270	COG0471	metal ion transport
Cop2CBH44_RS14270	COG3273	potassium ion transport
Cop2CBH44_RS14275	COG1218	3'(2'),5'-bisphosphate nucleotidase
Cop2CBH44_RS14285	COG0706	membrane insertase activity
Cop2CBH44_RS14290	COG0504	CTP synthase activity
Cop2CBH44_RS14305	COG3345	alpha-galactosidase
Cop2CBH44_RS14320	COG1678	Uncharacterized ACR, COG1678
Cop2CBH44_RS14330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Cop2CBH44_RS14335	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
Cop2CBH44_RS14340	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Cop2CBH44_RS14345	COG0590	tRNA wobble adenosine to inosine editing
Cop2CBH44_RS14355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Cop2CBH44_RS14375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Cop2CBH44_RS14400	COG0737	Belongs to the 5'-nucleotidase family
Cop2CBH44_RS14455	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Cop2CBH44_RS14460	COG0646	methionine synthase
Cop2CBH44_RS14460	COG1410	methionine synthase
Cop2CBH44_RS14475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Cop2CBH44_RS14480	COG0305	Participates in initiation and elongation during chromosome replication
Cop2CBH44_RS14485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Cop2CBH44_RS14495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Cop2CBH44_RS14500	COG0484	heat shock protein binding
Cop2CBH44_RS14505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Cop2CBH44_RS14510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Cop2CBH44_RS14515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Cop2CBH44_RS14520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Cop2CBH44_RS14535	COG3408	Glycogen debranching enzyme
Cop2CBH44_RS14545	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS14550	COG3119	arylsulfatase activity
Cop2CBH44_RS14560	COG3119	arylsulfatase activity
Cop2CBH44_RS14590	COG3119	arylsulfatase activity
Cop2CBH44_RS14600	COG4771	TonB-dependent receptor
Cop2CBH44_RS14605	COG0702	epimerase
Cop2CBH44_RS14610	COG1629	transport
Cop2CBH44_RS14610	COG4206	TonB-dependent receptor
Cop2CBH44_RS14630	COG0470	DNA polymerase III
Cop2CBH44_RS14665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Cop2CBH44_RS14700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Cop2CBH44_RS14725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Cop2CBH44_RS14730	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Cop2CBH44_RS14740	COG0110	maltose O-acetyltransferase activity
Cop2CBH44_RS14770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Cop2CBH44_RS14785	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS14790	COG1388	LysM domain
Cop2CBH44_RS14790	COG4641	Protein conserved in bacteria
Cop2CBH44_RS14795	COG1216	Glycosyl transferase, family 2
Cop2CBH44_RS14795	COG1442	glycosyl transferase family 8
Cop2CBH44_RS14805	COG2244	polysaccharide biosynthetic process
Cop2CBH44_RS14825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Cop2CBH44_RS14840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Cop2CBH44_RS14855	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Cop2CBH44_RS14860	COG0540	Belongs to the ATCase OTCase family
Cop2CBH44_RS14865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Cop2CBH44_RS14885	COG2431	L-lysine efflux transmembrane transporter activity
Cop2CBH44_RS14895	COG4464	protein tyrosine phosphatase activity
Cop2CBH44_RS14900	COG0254	rRNA binding
Cop2CBH44_RS14905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Cop2CBH44_RS14910	COG4753	response regulator
Cop2CBH44_RS14910	COG2207	Transcriptional regulator
Cop2CBH44_RS14930	COG2885	chlorophyll binding
Cop2CBH44_RS14945	COG1917	Cupin 2, conserved barrel domain protein
Cop2CBH44_RS14950	COG0671	phosphoesterase, PA-phosphatase related
Cop2CBH44_RS14960	COG3969	phosphoadenosine phosphosulfate
Cop2CBH44_RS14965	COG1475	DNA binding
Cop2CBH44_RS14970	COG0622	Phosphoesterase
Cop2CBH44_RS14975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Cop2CBH44_RS14975	COG1333	cytochrome c biogenesis protein
Cop2CBH44_RS14990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS14995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Cop2CBH44_RS15010	COG4206	TonB-dependent receptor
Cop2CBH44_RS15010	COG1629	transport
Cop2CBH44_RS15015	COG0513	Belongs to the DEAD box helicase family
Cop2CBH44_RS15030	COG0697	spore germination
Cop2CBH44_RS15035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Cop2CBH44_RS15040	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS15060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Cop2CBH44_RS15065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Cop2CBH44_RS15070	COG1136	(ABC) transporter
Cop2CBH44_RS15075	COG0577	efflux transmembrane transporter activity
Cop2CBH44_RS15075	COG1136	(ABC) transporter
Cop2CBH44_RS15080	COG1136	(ABC) transporter
Cop2CBH44_RS15080	COG0577	efflux transmembrane transporter activity
Cop2CBH44_RS15095	COG1162	GTPase activity
Cop2CBH44_RS15100	COG3345	alpha-galactosidase
Cop2CBH44_RS15105	COG0233	cytoplasmic translational termination
Cop2CBH44_RS15110	COG0528	UMP kinase activity
Cop2CBH44_RS15130	COG0792	nuclease activity
Cop2CBH44_RS15145	COG0590	tRNA wobble adenosine to inosine editing
Cop2CBH44_RS15150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Cop2CBH44_RS15155	COG2183	response to ionizing radiation
Cop2CBH44_RS15155	COG0539	negative regulation of cytoplasmic translation
Cop2CBH44_RS15160	COG0673	inositol 2-dehydrogenase activity
Cop2CBH44_RS15165	COG1234	tRNA 3'-trailer cleavage
Cop2CBH44_RS15190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Cop2CBH44_RS15190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Cop2CBH44_RS15195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Cop2CBH44_RS15200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Cop2CBH44_RS15205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Cop2CBH44_RS15210	COG0193	aminoacyl-tRNA hydrolase activity
Cop2CBH44_RS15215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Cop2CBH44_RS15220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Cop2CBH44_RS15225	COG1522	sequence-specific DNA binding
Cop2CBH44_RS15230	COG2873	o-acetylhomoserine
Cop2CBH44_RS15240	COG1592	Rubrerythrin
Cop2CBH44_RS15260	COG1119	ATPase activity
Cop2CBH44_RS15265	COG0698	ribose 5-phosphate isomerase
Cop2CBH44_RS15285	COG1929	Belongs to the glycerate kinase type-1 family
Cop2CBH44_RS15290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Cop2CBH44_RS15295	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Cop2CBH44_RS15310	COG1609	Transcriptional regulator
Cop2CBH44_RS15325	COG0738	Major facilitator superfamily
Cop2CBH44_RS15330	COG1069	ribulokinase activity
Cop2CBH44_RS15340	COG2832	Protein of unknown function (DUF454)
Cop2CBH44_RS15345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Cop2CBH44_RS15355	COG2843	Capsule synthesis protein
Cop2CBH44_RS15380	COG1271	oxidase subunit
Cop2CBH44_RS15390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Cop2CBH44_RS15395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Cop2CBH44_RS15410	COG3408	Glycogen debranching enzyme
Cop2CBH44_RS15415	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Cop2CBH44_RS15420	COG4124	Belongs to the glycosyl hydrolase 26 family
Cop2CBH44_RS15430	COG1629	transport
Cop2CBH44_RS15435	COG0702	epimerase
Cop2CBH44_RS15455	COG3458	cephalosporin-C deacetylase activity
Cop2CBH44_RS15515	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Cop2CBH44_RS15525	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS15530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS15535	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS15565	COG4771	TonB-dependent receptor
Cop2CBH44_RS15580	COG3119	arylsulfatase activity
Cop2CBH44_RS15595	COG4206	TonB-dependent receptor
Cop2CBH44_RS15595	COG1629	transport
Cop2CBH44_RS15615	COG0688	phosphatidylethanolamine metabolic process
Cop2CBH44_RS15620	COG1183	phosphatidylcholine synthase activity
Cop2CBH44_RS15630	COG0564	pseudouridine synthase activity
Cop2CBH44_RS15640	COG0217	transcriptional regulatory protein
Cop2CBH44_RS15655	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
Cop2CBH44_RS15665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Cop2CBH44_RS15675	COG0612	Peptidase, M16
Cop2CBH44_RS15685	COG1196	nuclear chromosome segregation
Cop2CBH44_RS15700	COG0514	ATP-dependent DNA helicase (RecQ)
Cop2CBH44_RS15710	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS15725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Cop2CBH44_RS15790	COG3292	Two component regulator propeller
Cop2CBH44_RS15790	COG2205	protein histidine kinase activity
Cop2CBH44_RS15790	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS15805	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS15820	COG0738	Major facilitator superfamily
Cop2CBH44_RS15825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Cop2CBH44_RS15845	COG0702	epimerase
Cop2CBH44_RS15850	COG4771	TonB-dependent receptor
Cop2CBH44_RS15860	COG2315	Protein conserved in bacteria
Cop2CBH44_RS15865	COG1733	regulation of RNA biosynthetic process
Cop2CBH44_RS15885	COG0628	permease
Cop2CBH44_RS15890	COG1435	thymidine kinase activity
Cop2CBH44_RS15900	COG2801	Transposase and inactivated derivatives
Cop2CBH44_RS15905	COG2027	D-alanyl-D-alanine carboxypeptidase
Cop2CBH44_RS15915	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Cop2CBH44_RS15955	COG3408	Glycogen debranching enzyme
Cop2CBH44_RS15960	COG3292	Two component regulator propeller
Cop2CBH44_RS15960	COG2205	protein histidine kinase activity
Cop2CBH44_RS15960	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS15995	COG4771	TonB-dependent receptor
Cop2CBH44_RS16005	COG3250	beta-galactosidase activity
Cop2CBH44_RS16030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Cop2CBH44_RS16035	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Cop2CBH44_RS16055	COG1629	transport
Cop2CBH44_RS16060	COG0702	epimerase
Cop2CBH44_RS16075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Cop2CBH44_RS16080	COG0745	RESPONSE REGULATOR receiver
Cop2CBH44_RS16080	COG2205	protein histidine kinase activity
Cop2CBH44_RS16080	COG3292	Two component regulator propeller
Cop2CBH44_RS16085	COG3458	cephalosporin-C deacetylase activity
Cop2CBH44_RS16095	COG0826	peptidase U32
Cop2CBH44_RS16100	COG0138	bifunctional purine biosynthesis protein purh
Cop2CBH44_RS16105	COG1077	Cell shape determining protein MreB Mrl
Cop2CBH44_RS16120	COG0768	penicillin binding
Cop2CBH44_RS16125	COG0772	Belongs to the SEDS family
Cop2CBH44_RS16160	COG1396	sequence-specific DNA binding
Cop2CBH44_RS16215	COG3561	AntA/AntB antirepressor
Cop2CBH44_RS16240	COG4974	Belongs to the 'phage' integrase family
Cop2CBH44_RS16250	COG1979	alcohol dehydrogenase
Cop2CBH44_RS16255	COG0523	cobalamin synthesis protein
Cop2CBH44_RS16295	COG0445	tRNA wobble uridine modification
Cop2CBH44_RS16310	COG4771	TonB-dependent receptor
Cop2CBH44_RS16315	COG0702	epimerase
Cop2CBH44_RS16340	COG0446	pyridine nucleotide-disulphide oxidoreductase
Cop2CBH44_RS16340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Cop2CBH44_RS16360	COG0446	pyridine nucleotide-disulphide oxidoreductase
Cop2CBH44_RS16360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Cop2CBH44_RS16365	COG3537	Alpha-1,2-mannosidase
Cop2CBH44_RS16370	COG0561	phosphatase activity
Cop2CBH44_RS16375	COG0738	Major facilitator superfamily
Cop2CBH44_RS16380	COG1349	DNA-binding transcription factor activity
Cop2CBH44_RS16390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Cop2CBH44_RS16405	COG0860	N-Acetylmuramoyl-L-alanine amidase