locus-tag	class	description
CARG_RS00010	COG0592	DNA-directed DNA polymerase activity
CARG_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CARG_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CARG_RS00025	COG0187	DNA topoisomerase II activity
CARG_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CARG_RS00125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CARG_RS00140	COG0515	serine threonine protein kinase
CARG_RS00140	COG2815	serine threonine protein kinase
CARG_RS00145	COG0515	serine threonine protein kinase
CARG_RS00150	COG0768	penicillin binding
CARG_RS00155	COG0772	Belongs to the SEDS family
CARG_RS00165	COG1716	ATPase activity
CARG_RS00170	COG1716	ATPase activity
CARG_RS00170	COG1716	ATPase activity
CARG_RS00180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CARG_RS00190	COG3180	Ammonia monooxygenase
CARG_RS00195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CARG_RS00205	COG2610	gluconate transmembrane transporter activity
CARG_RS00210	COG1309	transcriptional regulator
CARG_RS00225	COG0393	Putative heavy-metal-binding
CARG_RS00235	COG1643	Atp-dependent helicase
CARG_RS00240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CARG_RS00240	COG2169	Transcriptional regulator
CARG_RS00245	COG2818	Glycosylase
CARG_RS00260	COG2501	S4 domain
CARG_RS00280	COG3590	peptidase
CARG_RS00310	COG1028	Short-chain dehydrogenase reductase Sdr
CARG_RS00315	COG0277	FAD linked oxidase domain protein
CARG_RS00335	COG1216	Glycosyl transferase, family 2
CARG_RS00365	COG0477	Major facilitator Superfamily
CARG_RS00375	COG3237	CsbD-like
CARG_RS00390	COG0287	Prephenate dehydrogenase
CARG_RS00395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CARG_RS00415	COG2409	Drug exporters of the RND superfamily
CARG_RS00420	COG0343	queuine tRNA-ribosyltransferase activity
CARG_RS00430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CARG_RS00440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CARG_RS00455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CARG_RS00460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CARG_RS00465	COG1492	cobalamin metabolic process
CARG_RS00470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CARG_RS00490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CARG_RS00495	COG0697	spore germination
CARG_RS00500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CARG_RS00510	COG0527	aspartate kinase activity
CARG_RS00550	COG0651	ATP synthesis coupled electron transport
CARG_RS00555	COG1006	Multisubunit Na H antiporter MnhC subunit
CARG_RS00560	COG2111	Na H antiporter
CARG_RS00560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CARG_RS00580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CARG_RS00595	COG0251	oxidation-reduction process
CARG_RS00600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CARG_RS00605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CARG_RS00620	COG0494	nUDIX hydrolase
CARG_RS00675	COG1205	dead DEAH box helicase
CARG_RS00675	COG1111	helicase
CARG_RS00680	COG1278	Cold shock
CARG_RS00685	COG1754	DNA topoisomerase type I activity
CARG_RS00685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CARG_RS00700	COG5479	isomerase activity
CARG_RS00700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CARG_RS00715	COG1088	dTDP-glucose 4,6-dehydratase activity
CARG_RS00735	COG0463	Glycosyl transferase, family 2
CARG_RS00745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CARG_RS00745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CARG_RS00775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CARG_RS00780	COG1396	sequence-specific DNA binding
CARG_RS00780	COG3800	Transcriptional regulator
CARG_RS00790	COG1053	succinate dehydrogenase
CARG_RS00795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CARG_RS00805	COG2733	membrane
CARG_RS00815	COG0788	formyltetrahydrofolate deformylase activity
CARG_RS00820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CARG_RS00840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CARG_RS00845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CARG_RS00850	COG0318	PFAM AMP-dependent synthetase and ligase
CARG_RS00885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CARG_RS00895	COG0560	Phosphoserine phosphatase
CARG_RS00905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CARG_RS00910	COG0181	hydroxymethylbilane synthase activity
CARG_RS00915	COG1648	precorrin-2 dehydrogenase activity
CARG_RS00915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CARG_RS00920	COG0113	porphobilinogen synthase activity
CARG_RS00930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CARG_RS00935	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CARG_RS00945	COG0406	alpha-ribazole phosphatase activity
CARG_RS00950	COG0386	Belongs to the glutathione peroxidase family
CARG_RS00955	COG0785	Cytochrome C biogenesis protein
CARG_RS00965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CARG_RS01020	COG1129	ABC transporter
CARG_RS01045	COG4948	Mandelate Racemase Muconate Lactonizing
CARG_RS01060	COG0438	transferase activity, transferring glycosyl groups
CARG_RS01060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CARG_RS01070	COG0644	oxidoreductase
CARG_RS01075	COG0142	geranyltranstransferase activity
CARG_RS01100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CARG_RS01115	COG0081	regulation of translation
CARG_RS01150	COG0701	Predicted permease
CARG_RS01170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CARG_RS01200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CARG_RS01205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CARG_RS01220	COG4821	SIS domain
CARG_RS01245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CARG_RS01255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CARG_RS01280	COG0789	Transcriptional regulator
CARG_RS01285	COG2375	cellular response to nickel ion
CARG_RS01295	COG1028	Short-chain dehydrogenase reductase Sdr
CARG_RS01300	COG1012	belongs to the aldehyde dehydrogenase family
CARG_RS01320	COG0833	amino acid
CARG_RS01355	COG1136	(ABC) transporter
CARG_RS01370	COG1172	Belongs to the binding-protein-dependent transport system permease family
CARG_RS01380	COG0778	Nitroreductase
CARG_RS01395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CARG_RS01405	COG1841	ribosomal large subunit assembly
CARG_RS01410	COG0200	Binds to the 23S rRNA
CARG_RS01420	COG0201	protein transport
CARG_RS01440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CARG_RS01450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CARG_RS01455	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CARG_RS01465	COG0203	ribosomal protein L17
CARG_RS01470	COG0101	tRNA pseudouridine synthase activity
CARG_RS01485	COG0318	PFAM AMP-dependent synthetase and ligase
CARG_RS01495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CARG_RS01515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CARG_RS01525	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CARG_RS01530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CARG_RS01550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CARG_RS01550	COG3321	synthase
CARG_RS01550	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CARG_RS01565	COG0736	holo-[acyl-carrier-protein] synthase activity
CARG_RS01590	COG1376	ErfK ybiS ycfS ynhG family protein
CARG_RS01605	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CARG_RS01645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CARG_RS01650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CARG_RS01660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CARG_RS01700	COG3842	ATPase activity
CARG_RS01710	COG1316	TRANSCRIPTIONal
CARG_RS01720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CARG_RS01745	COG1482	cell wall glycoprotein biosynthetic process
CARG_RS01760	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CARG_RS01775	COG0326	Molecular chaperone. Has ATPase activity
CARG_RS01790	COG0745	RESPONSE REGULATOR receiver
CARG_RS01795	COG5002	protein histidine kinase activity
CARG_RS01795	COG5000	phosphorelay sensor kinase activity
CARG_RS01800	COG5401	PFAM Sporulation and spore germination
CARG_RS01810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CARG_RS01815	COG0653	protein targeting
CARG_RS01850	COG1162	GTPase activity
CARG_RS01855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CARG_RS01865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CARG_RS01895	COG0513	Belongs to the DEAD box helicase family
CARG_RS01920	COG0210	DNA helicase
CARG_RS01925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CARG_RS01930	COG2816	NAD+ diphosphatase activity
CARG_RS01950	COG3480	Lon protease (S16) C-terminal proteolytic domain
CARG_RS01965	COG1615	UPF0182 protein
CARG_RS02010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CARG_RS02015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CARG_RS02075	COG0483	inositol monophosphate 1-phosphatase activity
CARG_RS02080	COG0483	inositol monophosphate 1-phosphatase activity
CARG_RS02095	COG2884	Cell division ATP-binding protein ftsE
CARG_RS02100	COG2177	Part of the ABC transporter FtsEX involved in
CARG_RS02155	COG2217	Heavy metal translocating P-type atpase
CARG_RS02180	COG1309	transcriptional regulator
CARG_RS02240	COG1652	LysM domain
CARG_RS02245	COG1278	Cold shock
CARG_RS02270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CARG_RS02270	COG0512	Glutamine amidotransferase of anthranilate synthase
CARG_RS02275	COG2252	PERMEase
CARG_RS02300	COG0372	Belongs to the citrate synthase family
CARG_RS02305	COG0545	Peptidyl-prolyl cis-trans isomerase
CARG_RS02315	COG0656	L-ascorbic acid biosynthetic process
CARG_RS02325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CARG_RS02335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CARG_RS02345	COG0475	glutathione-regulated potassium exporter activity
CARG_RS02350	COG3757	hydrolase, family 25
CARG_RS02365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CARG_RS02650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CARG_RS02655	COG1218	3'(2'),5'-bisphosphate nucleotidase
CARG_RS02660	COG1201	RNA secondary structure unwinding
CARG_RS02665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CARG_RS02705	COG0138	bifunctional purine biosynthesis protein purh
CARG_RS02715	COG1309	transcriptional regulator
CARG_RS02730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CARG_RS02735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CARG_RS02740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CARG_RS02745	COG0254	rRNA binding
CARG_RS02755	COG0745	RESPONSE REGULATOR receiver
CARG_RS02765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CARG_RS02770	COG0521	Mo-molybdopterin cofactor biosynthetic process
CARG_RS02770	COG0315	cyclic pyranopterin monophosphate synthase activity
CARG_RS02775	COG1970	mechanosensitive ion channel activity
CARG_RS02790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CARG_RS02820	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CARG_RS02830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CARG_RS02840	COG0084	hydrolase, TatD family'
CARG_RS02845	COG3583	domain protein
CARG_RS02870	COG3971	2-oxopent-4-enoate hydratase activity
CARG_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
CARG_RS02895	COG0477	Major facilitator Superfamily
CARG_RS02910	COG1012	belongs to the aldehyde dehydrogenase family
CARG_RS02915	COG3961	Belongs to the TPP enzyme family
CARG_RS02925	COG1760	l-serine dehydratase
CARG_RS02930	COG0488	(ABC) transporter
CARG_RS02950	COG2326	polyphosphate kinase activity
CARG_RS02975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CARG_RS02980	COG0193	aminoacyl-tRNA hydrolase activity
CARG_RS03000	COG4139	cobalamin transport
CARG_RS03005	COG1120	ATPase activity
CARG_RS03020	COG1473	amidohydrolase
CARG_RS03025	COG0477	Major facilitator Superfamily
CARG_RS03050	COG1129	ABC transporter
CARG_RS03055	COG0010	Belongs to the arginase family
CARG_RS03060	COG1414	Transcriptional regulator
CARG_RS03065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CARG_RS03075	COG1228	amidohydrolase
CARG_RS03085	COG0193	aminoacyl-tRNA hydrolase activity
CARG_RS03105	COG0745	RESPONSE REGULATOR receiver
CARG_RS03110	COG2205	protein histidine kinase activity
CARG_RS03125	COG3971	2-oxopent-4-enoate hydratase activity
CARG_RS03140	COG4638	Rieske (2fe-2S)
CARG_RS03145	COG2146	nitrite reductase [NAD(P)H] activity
CARG_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
CARG_RS03165	COG0318	PFAM AMP-dependent synthetase and ligase
CARG_RS03180	COG0477	Major facilitator Superfamily
CARG_RS03205	COG1414	Transcriptional regulator
CARG_RS03230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CARG_RS03235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CARG_RS03245	COG1309	transcriptional regulator
CARG_RS03255	COG2837	iron assimilation
CARG_RS03265	COG0672	)-iron permease
CARG_RS03270	COG3956	TIGRFAM MazG family protein
CARG_RS03335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CARG_RS03380	COG1309	transcriptional regulator
CARG_RS03390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CARG_RS03395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CARG_RS03400	COG1914	H( )-stimulated, divalent metal cation uptake system
CARG_RS03410	COG0114	fumarate hydratase activity
CARG_RS03415	COG1494	fructose-1,6-bisphosphatase
CARG_RS03430	COG1570	exodeoxyribonuclease VII activity
CARG_RS03445	COG0628	permease
CARG_RS03455	COG0733	neurotransmitter:sodium symporter activity
CARG_RS03460	COG0012	GTP binding
CARG_RS03505	COG2354	Protein conserved in bacteria
CARG_RS03520	COG1122	ATPase activity
CARG_RS03530	COG4166	transmembrane transport
CARG_RS03535	COG0601	transmembrane transport
CARG_RS03540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CARG_RS03560	COG1217	gtp-binding protein TYPA
CARG_RS03565	COG0747	negative chemotaxis
CARG_RS03595	COG2171	N-acyltransferase activity
CARG_RS03600	COG1113	amino acid transport
CARG_RS03610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CARG_RS03615	COG1611	Belongs to the LOG family
CARG_RS03625	COG1621	beta-fructofuranosidase activity
CARG_RS03630	COG0297	glycogen (starch) synthase activity
CARG_RS03680	COG0598	Magnesium transport protein CorA
CARG_RS03690	COG0508	dehydrogenase complex catalyzes the overall conversion of
CARG_RS03690	COG0567	Dehydrogenase, E1 component
CARG_RS03695	COG1132	(ABC) transporter
CARG_RS03735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CARG_RS03765	COG1556	Lactate utilization protein
CARG_RS03770	COG1139	Iron-sulfur cluster binding protein
CARG_RS03775	COG0247	lactate metabolic process
CARG_RS03780	COG1620	l-lactate permease
CARG_RS03790	COG0019	diaminopimelate decarboxylase activity
CARG_RS03800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CARG_RS03810	COG0482	sulfurtransferase activity
CARG_RS03850	COG0154	amidase activity
CARG_RS03860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CARG_RS03865	COG1120	ATPase activity
CARG_RS03880	COG0205	6-phosphofructokinase activity
CARG_RS03890	COG3949	Membrane
CARG_RS03895	COG0583	DNA-binding transcription factor activity
CARG_RS03905	COG0129	dihydroxy-acid dehydratase activity
CARG_RS03915	COG0668	transmembrane transport
CARG_RS03920	COG0028	Belongs to the TPP enzyme family
CARG_RS03965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CARG_RS03970	COG0473	3-isopropylmalate dehydrogenase activity
CARG_RS03990	COG0179	Fumarylacetoacetate (FAA) hydrolase
CARG_RS04035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CARG_RS04040	COG0066	3-isopropylmalate dehydratase activity
CARG_RS04045	COG0494	nUDIX hydrolase
CARG_RS04045	COG0406	alpha-ribazole phosphatase activity
CARG_RS04050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CARG_RS04065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CARG_RS04070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CARG_RS04075	COG1461	Dihydroxyacetone kinase
CARG_RS04080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CARG_RS04090	COG0742	ribosomal rna small subunit methyltransferase
CARG_RS04095	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CARG_RS04115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CARG_RS04165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CARG_RS04190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CARG_RS04195	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CARG_RS04205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CARG_RS04210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CARG_RS04230	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CARG_RS04240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CARG_RS04245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CARG_RS04265	COG0137	argininosuccinate synthase activity
CARG_RS04280	COG0028	Belongs to the TPP enzyme family
CARG_RS04290	COG2835	tetraacyldisaccharide 4'-kinase activity
CARG_RS04295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CARG_RS04330	COG0647	UMP catabolic process
CARG_RS04340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CARG_RS04360	COG0494	nUDIX hydrolase
CARG_RS04365	COG4974	Belongs to the 'phage' integrase family
CARG_RS04375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CARG_RS04380	COG2897	thiosulfate sulfurtransferase activity
CARG_RS04385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CARG_RS04390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CARG_RS04405	COG1160	GTP binding
CARG_RS04425	COG0653	protein targeting
CARG_RS04430	COG1716	ATPase activity
CARG_RS04460	COG1253	flavin adenine dinucleotide binding
CARG_RS04465	COG0513	Belongs to the DEAD box helicase family
CARG_RS04470	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CARG_RS04480	COG0352	thiamine-phosphate diphosphorylase activity
CARG_RS04490	COG2022	thiamine diphosphate biosynthetic process
CARG_RS04500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CARG_RS04505	COG0351	phosphomethylpyrimidine kinase
CARG_RS04505	COG0352	thiamine-phosphate diphosphorylase activity
CARG_RS04505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CARG_RS04525	COG0277	FAD linked oxidase domain protein
CARG_RS04525	COG0247	lactate metabolic process
CARG_RS04530	COG0477	Major facilitator Superfamily
CARG_RS04550	COG0463	Glycosyl transferase, family 2
CARG_RS04570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CARG_RS04610	COG0805	protein transport
CARG_RS04625	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CARG_RS04640	COG4122	O-methyltransferase activity
CARG_RS04660	COG4592	Periplasmic binding protein
CARG_RS04665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CARG_RS04670	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CARG_RS04675	COG1120	ATPase activity
CARG_RS04690	COG1362	aminopeptidase activity
CARG_RS04700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CARG_RS04705	COG1027	Aspartate ammonia-lyase
CARG_RS04710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CARG_RS04715	COG0140	phosphoribosyl-ATP diphosphatase activity
CARG_RS04720	COG0560	Phosphoserine phosphatase
CARG_RS04725	COG1410	methionine synthase
CARG_RS04725	COG0646	methionine synthase
CARG_RS04735	COG0215	cysteine-tRNA ligase activity
CARG_RS04745	COG0667	Aldo Keto reductase
CARG_RS04755	COG0167	dihydroorotate dehydrogenase activity
CARG_RS04770	COG1132	(ABC) transporter
CARG_RS04825	COG3883	PFAM NLP P60 protein
CARG_RS04825	COG0791	NLP P60 protein
CARG_RS04845	COG0519	Catalyzes the synthesis of GMP from XMP
CARG_RS04860	COG0733	neurotransmitter:sodium symporter activity
CARG_RS04865	COG0488	(ABC) transporter
CARG_RS04875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CARG_RS04880	COG2151	metal-sulfur cluster biosynthetic enzyme
CARG_RS04895	COG0396	ATPase activity
CARG_RS04920	COG1131	(ABC) transporter
CARG_RS04940	COG0109	protoheme IX farnesyltransferase activity
CARG_RS04965	COG1136	(ABC) transporter
CARG_RS04970	COG4591	ABC-type transport system involved in lipoprotein release permease component
CARG_RS04975	COG5650	phosphatidylinositol metabolic process
CARG_RS04980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CARG_RS04990	COG0126	phosphoglycerate kinase activity
CARG_RS04995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CARG_RS05000	COG1481	regulation of sporulation
CARG_RS05015	COG0322	excinuclease ABC activity
CARG_RS05035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CARG_RS05040	COG0242	peptide deformylase activity
CARG_RS05060	COG1758	RNA polymerase activity
CARG_RS05065	COG0194	GDP metabolic process
CARG_RS05085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CARG_RS05095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CARG_RS05110	COG1090	epimerase
CARG_RS05125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CARG_RS05135	COG0006	proline dipeptidase activity
CARG_RS05140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CARG_RS05145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CARG_RS05150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CARG_RS05155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CARG_RS05165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CARG_RS05170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CARG_RS05175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CARG_RS05215	COG0124	histidyl-tRNA synthetase
CARG_RS05220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CARG_RS05235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CARG_RS05250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CARG_RS05255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CARG_RS05260	COG2255	four-way junction helicase activity
CARG_RS05265	COG0632	four-way junction helicase activity
CARG_RS05270	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CARG_RS05275	COG0217	transcriptional regulatory protein
CARG_RS05290	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CARG_RS05300	COG0438	transferase activity, transferring glycosyl groups
CARG_RS05305	COG1560	Kdo2-lipid A biosynthetic process
CARG_RS05310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CARG_RS05325	COG2837	iron assimilation
CARG_RS05380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CARG_RS05385	COG3253	May function as heme-dependent peroxidase
CARG_RS05395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CARG_RS05400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CARG_RS05435	COG1061	Type III restriction enzyme res subunit
CARG_RS05450	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CARG_RS05465	COG1321	iron dependent repressor
CARG_RS05470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CARG_RS05495	COG0450	alkyl hydroperoxide reductase
CARG_RS05510	COG1643	Atp-dependent helicase
CARG_RS05520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CARG_RS05525	COG1349	DNA-binding transcription factor activity
CARG_RS05530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CARG_RS05540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CARG_RS05540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CARG_RS05540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CARG_RS05545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CARG_RS05550	COG2233	PERMEase
CARG_RS05555	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CARG_RS05560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CARG_RS05575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CARG_RS05580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CARG_RS05585	COG1196	nuclear chromosome segregation
CARG_RS05595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CARG_RS05600	COG2137	regulation of response to DNA damage stimulus
CARG_RS05605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CARG_RS05615	COG1842	Phage shock protein A
CARG_RS05620	COG1396	sequence-specific DNA binding
CARG_RS05625	COG1546	Belongs to the CinA family
CARG_RS05625	COG1058	Belongs to the CinA family
CARG_RS05640	COG1674	ftsk spoiiie
CARG_RS05650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CARG_RS05655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CARG_RS05660	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CARG_RS05665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CARG_RS05695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CARG_RS05725	COG0779	Required for maturation of 30S ribosomal subunits
CARG_RS05735	COG0442	prolyl-tRNA aminoacylation
CARG_RS05740	COG3022	response to hydroperoxide
CARG_RS05750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CARG_RS05750	COG1648	precorrin-2 dehydrogenase activity
CARG_RS05760	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CARG_RS05770	COG4166	transmembrane transport
CARG_RS05780	COG1301	dicarboxylic acid transport
CARG_RS05795	COG0579	oxidoreductase
CARG_RS05840	COG0750	zinc metalloprotease
CARG_RS05845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CARG_RS05855	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CARG_RS05895	COG4974	Belongs to the 'phage' integrase family
CARG_RS05910	COG0792	nuclease activity
CARG_RS05925	COG0681	Belongs to the peptidase S26 family
CARG_RS05940	COG0336	Belongs to the RNA methyltransferase TrmD family
CARG_RS05945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CARG_RS05950	COG0385	Bile acid
CARG_RS05975	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CARG_RS05995	COG1196	nuclear chromosome segregation
CARG_RS06000	COG1115	amino acid carrier protein
CARG_RS06005	COG0571	ribonuclease III activity
CARG_RS06025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CARG_RS06055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CARG_RS06060	COG0058	SHG alpha-glucan phosphorylase activity
CARG_RS06065	COG0469	pyruvate kinase activity
CARG_RS06070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CARG_RS06085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CARG_RS06095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CARG_RS06110	COG0131	Imidazoleglycerol-phosphate dehydratase
CARG_RS06120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CARG_RS06165	COG1739	Uncharacterized protein family UPF0029
CARG_RS06170	COG0477	Major facilitator Superfamily
CARG_RS06175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CARG_RS06190	COG1119	ATPase activity
CARG_RS06195	COG0366	Alpha amylase catalytic
CARG_RS06210	COG0346	lactoylglutathione lyase activity
CARG_RS06215	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CARG_RS06245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CARG_RS06250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CARG_RS06255	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CARG_RS06260	COG0356	it plays a direct role in the translocation of protons across the membrane
CARG_RS06295	COG0318	PFAM AMP-dependent synthetase and ligase
CARG_RS06305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CARG_RS06310	COG0460	homoserine dehydrogenase
CARG_RS06335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CARG_RS06340	COG0583	DNA-binding transcription factor activity
CARG_RS06350	COG1024	Enoyl-CoA hydratase
CARG_RS06380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CARG_RS06390	COG0156	8-amino-7-oxononanoate synthase activity
CARG_RS06405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CARG_RS06420	COG0252	asparaginase activity
CARG_RS06430	COG2824	Alkylphosphonate utilization operon protein PhnA
CARG_RS06440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CARG_RS06445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CARG_RS06465	COG1496	oxidoreductase activity
CARG_RS06470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CARG_RS06475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CARG_RS06480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CARG_RS06495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CARG_RS06510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CARG_RS06515	COG0768	penicillin binding
CARG_RS06555	COG0142	geranyltranstransferase activity
CARG_RS06570	COG0515	serine threonine protein kinase
CARG_RS06570	COG2815	serine threonine protein kinase
CARG_RS06575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CARG_RS06595	COG1940	carbohydrate kinase activity
CARG_RS06600	COG0438	transferase activity, transferring glycosyl groups
CARG_RS06605	COG0791	NLP P60 protein
CARG_RS06610	COG0791	NLP P60 protein
CARG_RS06625	COG0723	plastoquinol--plastocyanin reductase activity
CARG_RS06630	COG2010	Cytochrome c
CARG_RS06670	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CARG_RS06675	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CARG_RS06680	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CARG_RS06685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CARG_RS06690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CARG_RS06700	COG0508	dehydrogenase complex catalyzes the overall conversion of
CARG_RS06705	COG0321	lipoyl(octanoyl) transferase activity
CARG_RS06725	COG0174	glutamine synthetase
CARG_RS06740	COG2271	Major facilitator Superfamily
CARG_RS06755	COG0174	glutamine synthetase
CARG_RS06790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CARG_RS06795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CARG_RS06820	COG0477	Major facilitator Superfamily
CARG_RS06835	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CARG_RS06860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CARG_RS06895	COG2860	membrane
CARG_RS06930	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CARG_RS06945	COG0423	glycine-tRNA ligase activity
CARG_RS06965	COG1381	Involved in DNA repair and RecF pathway recombination
CARG_RS06980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CARG_RS07015	COG1022	Amp-dependent synthetase and ligase
CARG_RS07040	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CARG_RS07045	COG1233	COG1233 Phytoene dehydrogenase and related
CARG_RS07065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CARG_RS07075	COG0601	transmembrane transport
CARG_RS07080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CARG_RS07085	COG4172	Belongs to the ABC transporter superfamily
CARG_RS07110	COG1879	ABC-type sugar transport system periplasmic component
CARG_RS07115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CARG_RS07120	COG1869	D-ribose catabolic process
CARG_RS07140	COG0656	L-ascorbic acid biosynthetic process
CARG_RS07150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CARG_RS07155	COG1120	ATPase activity
CARG_RS07160	COG1132	(ABC) transporter
CARG_RS07175	COG2226	methyltransferase
CARG_RS07175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CARG_RS07175	COG3433	isochorismatase activity
CARG_RS07200	COG3842	ATPase activity
CARG_RS07230	COG0268	Binds directly to 16S ribosomal RNA
CARG_RS07245	COG1555	photosystem II stabilization
CARG_RS07245	COG1596	polysaccharide export
CARG_RS07250	COG1307	EDD domain protein, DegV family
CARG_RS07255	COG0406	alpha-ribazole phosphatase activity
CARG_RS07265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CARG_RS07270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CARG_RS07275	COG1122	ATPase activity
CARG_RS07280	COG1268	BioY protein
CARG_RS07315	COG1530	ribonuclease E activity
CARG_RS07330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CARG_RS07335	COG4608	Belongs to the ABC transporter superfamily
CARG_RS07345	COG0747	negative chemotaxis
CARG_RS07350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CARG_RS07365	COG0285	dihydrofolate synthase activity
CARG_RS07380	COG0039	L-malate dehydrogenase activity
CARG_RS07385	COG1309	transcriptional regulator
CARG_RS07395	COG0740	serine-type endopeptidase activity
CARG_RS07405	COG0544	peptidyl-prolyl cis-trans isomerase activity
CARG_RS07440	COG0300	oxidoreductase activity
CARG_RS07445	COG4172	Belongs to the ABC transporter superfamily
CARG_RS07455	COG0601	transmembrane transport
CARG_RS07460	COG0747	negative chemotaxis
CARG_RS07475	COG0668	transmembrane transport
CARG_RS07500	COG3336	cytochrome c oxidase
CARG_RS07550	COG0189	ligase activity
CARG_RS07555	COG2897	thiosulfate sulfurtransferase activity
CARG_RS07560	COG4770	biotin carboxylase activity
CARG_RS07595	COG1473	amidohydrolase
CARG_RS07595	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CARG_RS07605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CARG_RS07610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CARG_RS07630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CARG_RS07635	COG1686	Belongs to the peptidase S11 family
CARG_RS07640	COG1295	ribonuclease BN
CARG_RS07645	COG0180	Tryptophanyl-tRNA synthetase
CARG_RS07655	COG2814	Major facilitator Superfamily
CARG_RS07660	COG2838	Isocitrate dehydrogenase
CARG_RS07680	COG2873	o-acetylhomoserine
CARG_RS07690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CARG_RS07695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CARG_RS07730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CARG_RS07735	COG1321	iron dependent repressor
CARG_RS07750	COG1121	(ABC) transporter
CARG_RS07755	COG0803	Belongs to the bacterial solute-binding protein 9 family
CARG_RS07770	COG0587	DNA-directed DNA polymerase activity
CARG_RS07775	COG1464	Belongs to the NlpA lipoprotein family
CARG_RS07790	COG2011	ABC-type metal ion transport system permease component
CARG_RS07815	COG2197	response regulator
CARG_RS07835	COG0516	GMP reductase activity
CARG_RS07875	COG0456	acetyltransferase
CARG_RS07885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CARG_RS07900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CARG_RS07925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CARG_RS07965	COG1674	ftsk spoiiie
CARG_RS07975	COG1404	Belongs to the peptidase S8 family
CARG_RS08000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CARG_RS08015	COG3265	gluconokinase activity
CARG_RS08020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CARG_RS08035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CARG_RS08040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CARG_RS08070	COG1115	amino acid carrier protein
CARG_RS08120	COG2197	response regulator
CARG_RS08125	COG1045	serine acetyltransferase
CARG_RS08135	COG0310	cobalt ion transport
CARG_RS08140	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CARG_RS08190	COG0183	Belongs to the thiolase family
CARG_RS08195	COG1024	Enoyl-CoA hydratase
CARG_RS08200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CARG_RS08205	COG1960	acyl-CoA dehydrogenase activity
CARG_RS08215	COG0123	including yeast histone deacetylase and acetoin utilization protein
CARG_RS08225	COG0456	acetyltransferase
CARG_RS08245	COG0354	folic acid binding
CARG_RS08280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CARG_RS08285	COG0047	phosphoribosylformylglycinamidine synthase activity
CARG_RS08290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CARG_RS08305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CARG_RS08310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CARG_RS08315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CARG_RS08320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CARG_RS08325	COG0436	Aminotransferase
CARG_RS08330	COG0569	domain protein
CARG_RS08335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CARG_RS08340	COG0151	Belongs to the GarS family
CARG_RS08345	COG0537	adenosine 5'-monophosphoramidase activity
CARG_RS08360	COG2205	protein histidine kinase activity
CARG_RS08365	COG0745	RESPONSE REGULATOR receiver
CARG_RS08370	COG0028	Belongs to the TPP enzyme family
CARG_RS08375	COG1335	isochorismatase
CARG_RS08410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CARG_RS08415	COG0215	cysteine-tRNA ligase activity
CARG_RS08420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CARG_RS08425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CARG_RS08430	COG1329	Transcriptional regulator
CARG_RS08435	COG2847	Copper chaperone PCu(A)C
CARG_RS08445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CARG_RS08455	COG0288	reversible hydration of carbon dioxide
CARG_RS08460	COG1194	a g-specific adenine glycosylase
CARG_RS08485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CARG_RS08510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CARG_RS08515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CARG_RS08525	COG0302	gtp cyclohydrolase
CARG_RS08530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CARG_RS08535	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CARG_RS08540	COG0037	tRNA processing
CARG_RS08545	COG2027	D-alanyl-D-alanine carboxypeptidase
CARG_RS08550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CARG_RS08565	COG2326	polyphosphate kinase activity
CARG_RS08570	COG0459	protein refolding
CARG_RS08600	COG0242	peptide deformylase activity
CARG_RS08610	COG0708	Exodeoxyribonuclease III
CARG_RS08615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CARG_RS08625	COG1131	(ABC) transporter
CARG_RS08650	COG0280	phosphate acetyltransferase
CARG_RS08660	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CARG_RS08665	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CARG_RS08675	COG4166	transmembrane transport
CARG_RS08685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CARG_RS08690	COG4129	membrane
CARG_RS08695	COG0191	fructose-bisphosphate aldolase activity
CARG_RS08725	COG0542	response to heat
CARG_RS08755	COG0789	Transcriptional regulator
CARG_RS08765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CARG_RS08785	COG0247	lactate metabolic process
CARG_RS08785	COG2181	nitrate reductase activity
CARG_RS08805	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CARG_RS08815	COG1174	glycine betaine transport
CARG_RS08820	COG1174	glycine betaine transport
CARG_RS08830	COG0717	Belongs to the dCTP deaminase family
CARG_RS08835	COG0586	Pfam SNARE associated Golgi protein
CARG_RS08860	COG1511	domain protein
CARG_RS08880	COG1472	Belongs to the glycosyl hydrolase 3 family
CARG_RS08895	COG4981	capsule polysaccharide biosynthetic process
CARG_RS08910	COG2755	lipolytic protein G-D-S-L family
CARG_RS08910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CARG_RS08915	COG0438	transferase activity, transferring glycosyl groups
CARG_RS08920	COG0500	methyltransferase
CARG_RS08925	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CARG_RS08955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CARG_RS08960	COG3321	synthase
CARG_RS08960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CARG_RS08960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CARG_RS08965	COG0318	PFAM AMP-dependent synthetase and ligase
CARG_RS08970	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CARG_RS08980	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CARG_RS08980	COG5479	isomerase activity
CARG_RS08990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CARG_RS08995	COG0671	phosphoesterase, PA-phosphatase related
CARG_RS09000	COG1216	Glycosyl transferase, family 2
CARG_RS09005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CARG_RS09020	COG1690	Belongs to the RtcB family
CARG_RS09035	COG0561	phosphatase activity
CARG_RS09050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CARG_RS09055	COG2188	Transcriptional regulator
CARG_RS09070	COG0588	phosphoglycerate mutase activity
CARG_RS09075	COG0077	Prephenate dehydratase
CARG_RS09105	COG1316	TRANSCRIPTIONal
CARG_RS09110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CARG_RS09120	COG2814	Major facilitator Superfamily
CARG_RS09140	COG2197	response regulator
CARG_RS09165	COG0706	membrane insertase activity
CARG_RS09170	COG1309	transcriptional regulator
CARG_RS09180	COG0589	response to stress
CARG_RS09220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CARG_RS09245	COG0305	Participates in initiation and elongation during chromosome replication
CARG_RS09270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CARG_RS09290	COG1054	Belongs to the UPF0176 family
CARG_RS09305	COG0495	leucyl-tRNA aminoacylation
CARG_RS09315	COG3715	PTS system
CARG_RS09320	COG3716	PTS system mannose fructose sorbose family IID component
CARG_RS09345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CARG_RS09350	COG0512	Glutamine amidotransferase of anthranilate synthase
CARG_RS09355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CARG_RS09360	COG0135	phosphoribosylanthranilate isomerase activity
CARG_RS09360	COG0134	indole-3-glycerol-phosphate synthase activity
CARG_RS09370	COG0159	tryptophan synthase activity
CARG_RS09410	COG1595	DNA-templated transcription, initiation
CARG_RS09420	COG3118	belongs to the thioredoxin family
CARG_RS09425	COG0860	N-Acetylmuramoyl-L-alanine amidase
CARG_RS09425	COG3409	Peptidoglycan-binding domain 1 protein
CARG_RS09435	COG1192	Involved in chromosome partitioning
CARG_RS09440	COG0357	Ribosomal RNA small subunit methyltransferase G
CARG_RS09445	COG0706	membrane insertase activity
CARG_RS09450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CARG_RS09455	COG0594	ribonuclease P activity
CARG_RS09550	COG0629	single-stranded DNA binding
CARG_RS09590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CARG_RS09630	COG2378	regulation of single-species biofilm formation
CARG_RS09680	COG0366	Alpha amylase catalytic
CARG_RS09685	COG0492	ferredoxin-NADP+ reductase activity
CARG_RS09705	COG0791	NLP P60 protein