locus-tag	class	description
CAURI_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAURI_RS00140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAURI_RS00145	COG0592	DNA-directed DNA polymerase activity
CAURI_RS00150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CAURI_RS00160	COG0187	DNA topoisomerase II activity
CAURI_RS00185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CAURI_RS00215	COG0726	polysaccharide deacetylase
CAURI_RS00235	COG1132	(ABC) transporter
CAURI_RS00255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAURI_RS00300	COG0515	serine threonine protein kinase
CAURI_RS00300	COG2815	serine threonine protein kinase
CAURI_RS00305	COG0515	serine threonine protein kinase
CAURI_RS00310	COG0768	penicillin binding
CAURI_RS00325	COG1716	ATPase activity
CAURI_RS00330	COG1716	ATPase activity
CAURI_RS00330	COG1716	ATPase activity
CAURI_RS00350	COG2801	Transposase and inactivated derivatives
CAURI_RS00385	COG2801	Transposase and inactivated derivatives
CAURI_RS00390	COG2963	transposase activity
CAURI_RS00405	COG2801	Transposase and inactivated derivatives
CAURI_RS00410	COG2963	transposase activity
CAURI_RS00435	COG2963	transposase activity
CAURI_RS00440	COG2801	Transposase and inactivated derivatives
CAURI_RS00480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAURI_RS00485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CAURI_RS00495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAURI_RS00505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAURI_RS00510	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CAURI_RS00515	COG0659	secondary active sulfate transmembrane transporter activity
CAURI_RS00520	COG1528	Iron-storage protein
CAURI_RS00550	COG3180	Ammonia monooxygenase
CAURI_RS00555	COG0730	response to heat
CAURI_RS00560	COG1643	Atp-dependent helicase
CAURI_RS00565	COG0110	maltose O-acetyltransferase activity
CAURI_RS00580	COG1012	belongs to the aldehyde dehydrogenase family
CAURI_RS00585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAURI_RS00595	COG1280	lysine exporter protein (LysE YggA)
CAURI_RS00600	COG2501	S4 domain
CAURI_RS00635	COG3590	peptidase
CAURI_RS00660	COG0277	FAD linked oxidase domain protein
CAURI_RS00690	COG1216	Glycosyl transferase, family 2
CAURI_RS00725	COG0604	alcohol dehydrogenase
CAURI_RS00725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAURI_RS00725	COG3321	synthase
CAURI_RS00725	COG4221	oxidoreductase activity
CAURI_RS00745	COG2026	Addiction module toxin, RelE StbE family
CAURI_RS00755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAURI_RS00780	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAURI_RS00780	COG0315	cyclic pyranopterin monophosphate synthase activity
CAURI_RS00795	COG1950	PFAM Membrane protein of
CAURI_RS00805	COG3961	Belongs to the TPP enzyme family
CAURI_RS00810	COG1113	amino acid transport
CAURI_RS00815	COG3835	regulator
CAURI_RS00860	COG1511	domain protein
CAURI_RS00865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAURI_RS00870	COG0569	domain protein
CAURI_RS00875	COG2149	membrane
CAURI_RS00885	COG0471	metal ion transport
CAURI_RS00890	COG0523	cobalamin synthesis protein
CAURI_RS00920	COG0287	Prephenate dehydrogenase
CAURI_RS00945	COG2409	Drug exporters of the RND superfamily
CAURI_RS00950	COG0343	queuine tRNA-ribosyltransferase activity
CAURI_RS01000	COG1100	Small GTP-binding protein
CAURI_RS01015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAURI_RS01035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAURI_RS01065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAURI_RS01090	COG0697	spore germination
CAURI_RS01095	COG0527	aspartate kinase activity
CAURI_RS01100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAURI_RS01120	COG3764	Sortase (surface protein transpeptidase)
CAURI_RS01130	COG3949	Membrane
CAURI_RS01175	COG1408	metallophosphoesterase
CAURI_RS01200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAURI_RS01205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAURI_RS01215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAURI_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAURI_RS01245	COG0601	transmembrane transport
CAURI_RS01250	COG4166	transmembrane transport
CAURI_RS01255	COG0596	Alpha beta hydrolase
CAURI_RS01310	COG1205	dead DEAH box helicase
CAURI_RS01310	COG1111	helicase
CAURI_RS01315	COG1278	Cold shock
CAURI_RS01325	COG1754	DNA topoisomerase type I activity
CAURI_RS01325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAURI_RS01365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CAURI_RS01370	COG0363	glucosamine-6-phosphate deaminase activity
CAURI_RS01375	COG2190	(PTS) system
CAURI_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAURI_RS01375	COG1263	PTS System
CAURI_RS01380	COG0318	PFAM AMP-dependent synthetase and ligase
CAURI_RS01395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAURI_RS01405	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CAURI_RS01405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAURI_RS01425	COG1088	dTDP-glucose 4,6-dehydratase activity
CAURI_RS01445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAURI_RS01450	COG1396	sequence-specific DNA binding
CAURI_RS01450	COG3800	Transcriptional regulator
CAURI_RS01460	COG1053	succinate dehydrogenase
CAURI_RS01465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CAURI_RS01475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CAURI_RS01480	COG1061	Type III restriction enzyme res subunit
CAURI_RS01485	COG1002	Type II restriction enzyme, methylase subunits
CAURI_RS01490	COG2801	Transposase and inactivated derivatives
CAURI_RS01500	COG1002	Type II restriction enzyme, methylase subunits
CAURI_RS01505	COG2733	membrane
CAURI_RS01520	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CAURI_RS01540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CAURI_RS01545	COG1854	S-ribosylhomocysteine lyase activity
CAURI_RS01560	COG1690	Belongs to the RtcB family
CAURI_RS01570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAURI_RS01580	COG0318	PFAM AMP-dependent synthetase and ligase
CAURI_RS01585	COG0318	PFAM AMP-dependent synthetase and ligase
CAURI_RS01590	COG0438	transferase activity, transferring glycosyl groups
CAURI_RS01600	COG5002	protein histidine kinase activity
CAURI_RS01605	COG0745	RESPONSE REGULATOR receiver
CAURI_RS01625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CAURI_RS01655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CAURI_RS01660	COG0181	hydroxymethylbilane synthase activity
CAURI_RS01665	COG1648	precorrin-2 dehydrogenase activity
CAURI_RS01665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAURI_RS01670	COG0113	porphobilinogen synthase activity
CAURI_RS01685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CAURI_RS01690	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CAURI_RS01695	COG4115	mRNA cleavage
CAURI_RS01700	COG2161	toxin-antitoxin pair type II binding
CAURI_RS01705	COG0488	(ABC) transporter
CAURI_RS01730	COG2076	Multidrug Resistance protein
CAURI_RS01750	COG0577	efflux transmembrane transporter activity
CAURI_RS01750	COG1136	(ABC) transporter
CAURI_RS01755	COG1136	(ABC) transporter
CAURI_RS01770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAURI_RS01775	COG0406	alpha-ribazole phosphatase activity
CAURI_RS01785	COG0785	Cytochrome C biogenesis protein
CAURI_RS01790	COG1333	cytochrome c biogenesis protein
CAURI_RS01795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAURI_RS01815	COG1575	Belongs to the MenA family. Type 1 subfamily
CAURI_RS01820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAURI_RS01825	COG1321	iron dependent repressor
CAURI_RS01825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAURI_RS01830	COG1121	(ABC) transporter
CAURI_RS01835	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAURI_RS01840	COG1321	iron dependent repressor
CAURI_RS01850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CAURI_RS01865	COG3069	C4-dicarboxylate transmembrane transporter activity
CAURI_RS01870	COG4948	Mandelate Racemase Muconate Lactonizing
CAURI_RS01895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CAURI_RS01895	COG0438	transferase activity, transferring glycosyl groups
CAURI_RS01900	COG2226	methyltransferase
CAURI_RS01910	COG0142	geranyltranstransferase activity
CAURI_RS01920	COG0435	Glutathione S-transferase
CAURI_RS01940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAURI_RS01950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CAURI_RS01955	COG0081	regulation of translation
CAURI_RS01960	COG0019	diaminopimelate decarboxylase activity
CAURI_RS01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS01990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS01995	COG1120	ATPase activity
CAURI_RS02000	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAURI_RS02005	COG0222	ribosome binding
CAURI_RS02025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CAURI_RS02035	COG4721	ABC-type cobalt transport system, permease component
CAURI_RS02040	COG1122	ATPase activity
CAURI_RS02055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CAURI_RS02060	COG0049	tRNA binding
CAURI_RS02065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAURI_RS02070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAURI_RS02110	COG1302	Protein conserved in bacteria
CAURI_RS02115	COG0051	transcription antitermination factor activity, RNA binding
CAURI_RS02120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CAURI_RS02125	COG0088	Forms part of the polypeptide exit tunnel
CAURI_RS02130	COG0089	rRNA binding
CAURI_RS02135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAURI_RS02140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CAURI_RS02145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CAURI_RS02150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CAURI_RS02155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CAURI_RS02160	COG0255	Belongs to the universal ribosomal protein uL29 family
CAURI_RS02165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CAURI_RS02185	COG1621	beta-fructofuranosidase activity
CAURI_RS02195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAURI_RS02205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CAURI_RS02210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAURI_RS02215	COG1215	transferase activity, transferring glycosyl groups
CAURI_RS02225	COG1215	transferase activity, transferring glycosyl groups
CAURI_RS02255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAURI_RS02265	COG2963	transposase activity
CAURI_RS02285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CAURI_RS02290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CAURI_RS02295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAURI_RS02305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAURI_RS02320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CAURI_RS02325	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CAURI_RS02330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CAURI_RS02335	COG1841	ribosomal large subunit assembly
CAURI_RS02340	COG0200	Binds to the 23S rRNA
CAURI_RS02350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAURI_RS02355	COG0201	protein transport
CAURI_RS02360	COG0563	adenylate kinase activity
CAURI_RS02380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAURI_RS02385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CAURI_RS02390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CAURI_RS02395	COG0202	RNA polymerase activity
CAURI_RS02400	COG0203	ribosomal protein L17
CAURI_RS02405	COG0101	tRNA pseudouridine synthase activity
CAURI_RS02415	COG1404	Belongs to the peptidase S8 family
CAURI_RS02425	COG1674	ftsk spoiiie
CAURI_RS02450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CAURI_RS02455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAURI_RS02485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CAURI_RS02490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAURI_RS02500	COG0569	domain protein
CAURI_RS02500	COG2985	domain, Protein
CAURI_RS02515	COG0456	acetyltransferase
CAURI_RS02520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAURI_RS02540	COG0577	efflux transmembrane transporter activity
CAURI_RS02540	COG1136	(ABC) transporter
CAURI_RS02550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAURI_RS02590	COG0516	GMP reductase activity
CAURI_RS02665	COG2011	ABC-type metal ion transport system permease component
CAURI_RS02675	COG1464	Belongs to the NlpA lipoprotein family
CAURI_RS02685	COG0587	DNA-directed DNA polymerase activity
CAURI_RS02725	COG0469	pyruvate kinase activity
CAURI_RS02730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CAURI_RS02735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CAURI_RS02745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAURI_RS02750	COG2873	o-acetylhomoserine
CAURI_RS02770	COG1595	DNA-templated transcription, initiation
CAURI_RS02780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAURI_RS02815	COG2838	Isocitrate dehydrogenase
CAURI_RS02820	COG2814	Major facilitator Superfamily
CAURI_RS02835	COG0180	Tryptophanyl-tRNA synthetase
CAURI_RS02850	COG1686	Belongs to the peptidase S11 family
CAURI_RS02875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAURI_RS02880	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CAURI_RS02880	COG1473	amidohydrolase
CAURI_RS02895	COG1396	sequence-specific DNA binding
CAURI_RS02895	COG3800	Transcriptional regulator
CAURI_RS02900	COG2079	MmgE PrpD family protein
CAURI_RS02905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CAURI_RS02910	COG0372	Belongs to the citrate synthase family
CAURI_RS02920	COG1136	(ABC) transporter
CAURI_RS02940	COG3547	Transposase (IS116 IS110 IS902 family)
CAURI_RS02945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CAURI_RS02950	COG1484	DNA-dependent DNA replication
CAURI_RS02965	COG4770	biotin carboxylase activity
CAURI_RS02970	COG2897	thiosulfate sulfurtransferase activity
CAURI_RS02975	COG0189	ligase activity
CAURI_RS02990	COG0424	maF-like protein
CAURI_RS03000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAURI_RS03005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAURI_RS03040	COG3842	ATPase activity
CAURI_RS03050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CAURI_RS03050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CAURI_RS03060	COG3527	Alpha-acetolactate decarboxylase
CAURI_RS03075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAURI_RS03115	COG1024	Enoyl-CoA hydratase
CAURI_RS03115	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAURI_RS03125	COG1914	H( )-stimulated, divalent metal cation uptake system
CAURI_RS03130	COG4336	lyase activity
CAURI_RS03140	COG4770	biotin carboxylase activity
CAURI_RS03145	COG1984	allophanate hydrolase subunit 2
CAURI_RS03150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CAURI_RS03210	COG0814	amino acid
CAURI_RS03215	COG2235	arginine
CAURI_RS03240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAURI_RS03255	COG2186	Transcriptional regulator
CAURI_RS03260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAURI_RS03265	COG2113	Glycine betaine
CAURI_RS03280	COG0517	IMP dehydrogenase activity
CAURI_RS03280	COG4175	Glycine betaine
CAURI_RS03285	COG2040	homocysteine
CAURI_RS03295	COG3265	gluconokinase activity
CAURI_RS03300	COG2610	gluconate transmembrane transporter activity
CAURI_RS03325	COG3835	regulator
CAURI_RS03335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAURI_RS03345	COG2315	Protein conserved in bacteria
CAURI_RS03350	COG1024	Enoyl-CoA hydratase
CAURI_RS03365	COG1960	acyl-CoA dehydrogenase activity
CAURI_RS03370	COG0659	secondary active sulfate transmembrane transporter activity
CAURI_RS03380	COG3835	regulator
CAURI_RS03405	COG0657	acetylesterase activity
CAURI_RS03410	COG2072	flavoprotein involved in K transport
CAURI_RS03445	COG1012	belongs to the aldehyde dehydrogenase family
CAURI_RS03450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAURI_RS03455	COG0814	amino acid
CAURI_RS03460	COG0028	Belongs to the TPP enzyme family
CAURI_RS03485	COG1316	TRANSCRIPTIONal
CAURI_RS03525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAURI_RS03540	COG0730	response to heat
CAURI_RS03545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAURI_RS03545	COG1648	precorrin-2 dehydrogenase activity
CAURI_RS03555	COG1482	cell wall glycoprotein biosynthetic process
CAURI_RS03575	COG0745	RESPONSE REGULATOR receiver
CAURI_RS03580	COG5002	protein histidine kinase activity
CAURI_RS03585	COG5401	PFAM Sporulation and spore germination
CAURI_RS03595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAURI_RS03600	COG0653	protein targeting
CAURI_RS03630	COG1162	GTPase activity
CAURI_RS03635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CAURI_RS03640	COG2135	peptidase activity
CAURI_RS03645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAURI_RS03655	COG5662	AntiSigma factor
CAURI_RS03675	COG0513	Belongs to the DEAD box helicase family
CAURI_RS03705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAURI_RS03710	COG2816	NAD+ diphosphatase activity
CAURI_RS03715	COG0210	DNA helicase
CAURI_RS03735	COG3480	Lon protease (S16) C-terminal proteolytic domain
CAURI_RS03760	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CAURI_RS03770	COG3878	Protein conserved in bacteria
CAURI_RS03775	COG4762	Protein conserved in bacteria
CAURI_RS03780	COG2311	Membrane
CAURI_RS03820	COG1120	ATPase activity
CAURI_RS03830	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS03835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS03860	COG0483	inositol monophosphate 1-phosphatase activity
CAURI_RS03865	COG0483	inositol monophosphate 1-phosphatase activity
CAURI_RS03870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CAURI_RS03875	COG2884	Cell division ATP-binding protein ftsE
CAURI_RS03880	COG2177	Part of the ABC transporter FtsEX involved in
CAURI_RS03895	COG0814	amino acid
CAURI_RS03900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAURI_RS03910	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CAURI_RS03920	COG4607	ABC-type enterochelin transport system periplasmic component
CAURI_RS03990	COG1061	Type III restriction enzyme res subunit
CAURI_RS04015	COG1652	LysM domain
CAURI_RS04040	COG2252	PERMEase
CAURI_RS04045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAURI_RS04065	COG0372	Belongs to the citrate synthase family
CAURI_RS04070	COG0545	Peptidyl-prolyl cis-trans isomerase
CAURI_RS04085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAURI_RS04095	COG3757	hydrolase, family 25
CAURI_RS04105	COG1765	OsmC-like protein
CAURI_RS04130	COG2801	Transposase and inactivated derivatives
CAURI_RS04150	COG1132	(ABC) transporter
CAURI_RS04155	COG2375	cellular response to nickel ion
CAURI_RS04155	COG1132	(ABC) transporter
CAURI_RS04160	COG1129	ABC transporter
CAURI_RS04185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAURI_RS04195	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAURI_RS04200	COG1218	3'(2'),5'-bisphosphate nucleotidase
CAURI_RS04205	COG1201	RNA secondary structure unwinding
CAURI_RS04215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAURI_RS04220	COG3304	Inner membrane component domain
CAURI_RS04240	COG1605	Chorismate mutase
CAURI_RS04270	COG0739	heme binding
CAURI_RS04285	COG0138	bifunctional purine biosynthesis protein purh
CAURI_RS04335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CAURI_RS04340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CAURI_RS04345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CAURI_RS04350	COG0254	rRNA binding
CAURI_RS04365	COG2205	protein histidine kinase activity
CAURI_RS04370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAURI_RS04375	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAURI_RS04375	COG0315	cyclic pyranopterin monophosphate synthase activity
CAURI_RS04385	COG1970	mechanosensitive ion channel activity
CAURI_RS04400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CAURI_RS04420	COG0519	Catalyzes the synthesis of GMP from XMP
CAURI_RS04435	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CAURI_RS04445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAURI_RS04470	COG0456	acetyltransferase
CAURI_RS04475	COG0084	hydrolase, TatD family'
CAURI_RS04480	COG3583	domain protein
CAURI_RS04500	COG0488	(ABC) transporter
CAURI_RS04530	COG0561	phosphatase activity
CAURI_RS04545	COG0438	transferase activity, transferring glycosyl groups
CAURI_RS04575	COG2985	domain, Protein
CAURI_RS04575	COG0569	domain protein
CAURI_RS04580	COG0183	Belongs to the thiolase family
CAURI_RS04585	COG1024	Enoyl-CoA hydratase
CAURI_RS04600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAURI_RS04610	COG1960	acyl-CoA dehydrogenase activity
CAURI_RS04620	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAURI_RS04645	COG2610	gluconate transmembrane transporter activity
CAURI_RS04650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAURI_RS04655	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CAURI_RS04665	COG0193	aminoacyl-tRNA hydrolase activity
CAURI_RS04670	COG2070	2-Nitropropane dioxygenase
CAURI_RS04680	COG2326	polyphosphate kinase activity
CAURI_RS04690	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAURI_RS04695	COG0193	aminoacyl-tRNA hydrolase activity
CAURI_RS04705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CAURI_RS04710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CAURI_RS04720	COG2132	Multicopper oxidase
CAURI_RS04750	COG1857	crispr-associated protein
CAURI_RS04765	COG1518	maintenance of DNA repeat elements
CAURI_RS04770	COG2860	membrane
CAURI_RS04795	COG0531	amino acid
CAURI_RS04800	COG3956	TIGRFAM MazG family protein
CAURI_RS04815	COG0148	phosphopyruvate hydratase activity
CAURI_RS04885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CAURI_RS04900	COG1072	(Pantothenic acid kinase))
CAURI_RS04925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAURI_RS04940	COG0477	Major facilitator Superfamily
CAURI_RS04950	COG0114	fumarate hydratase activity
CAURI_RS04955	COG1494	fructose-1,6-bisphosphatase
CAURI_RS04970	COG1722	exodeoxyribonuclease VII activity
CAURI_RS04975	COG1570	exodeoxyribonuclease VII activity
CAURI_RS04990	COG1322	Protein conserved in bacteria
CAURI_RS05000	COG0012	GTP binding
CAURI_RS05010	COG0693	protein deglycase activity
CAURI_RS05015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CAURI_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
CAURI_RS05040	COG2814	Major facilitator Superfamily
CAURI_RS05055	COG1484	DNA-dependent DNA replication
CAURI_RS05060	COG1823	symporter activity
CAURI_RS05065	COG0095	Lipoate-protein ligase
CAURI_RS05070	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CAURI_RS05075	COG0243	molybdopterin cofactor binding
CAURI_RS05075	COG3383	formate dehydrogenase (NAD+) activity
CAURI_RS05080	COG3383	formate dehydrogenase (NAD+) activity
CAURI_RS05080	COG0243	molybdopterin cofactor binding
CAURI_RS05085	COG0437	4 iron, 4 sulfur cluster binding
CAURI_RS05095	COG0709	Synthesizes selenophosphate from selenide and ATP
CAURI_RS05125	COG0428	transporter
CAURI_RS05130	COG2354	Protein conserved in bacteria
CAURI_RS05145	COG1217	gtp-binding protein TYPA
CAURI_RS05175	COG0564	pseudouridine synthase activity
CAURI_RS05185	COG1476	TRANSCRIPTIONal
CAURI_RS05195	COG1113	amino acid transport
CAURI_RS05205	COG1113	amino acid transport
CAURI_RS05210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAURI_RS05215	COG1611	Belongs to the LOG family
CAURI_RS05220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CAURI_RS05225	COG0463	Glycosyl transferase, family 2
CAURI_RS05245	COG0297	glycogen (starch) synthase activity
CAURI_RS05250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CAURI_RS05260	COG1595	DNA-templated transcription, initiation
CAURI_RS05295	COG1484	DNA-dependent DNA replication
CAURI_RS05300	COG0567	Dehydrogenase, E1 component
CAURI_RS05300	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAURI_RS05310	COG2272	Belongs to the type-B carboxylesterase lipase family
CAURI_RS05335	COG2814	Major facilitator Superfamily
CAURI_RS05345	COG0494	nUDIX hydrolase
CAURI_RS05350	COG0010	Belongs to the arginase family
CAURI_RS05360	COG3314	Sporulation integral membrane protein YlbJ
CAURI_RS05370	COG2986	histidine ammonia-lyase
CAURI_RS05380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CAURI_RS05385	COG1228	amidohydrolase
CAURI_RS05405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAURI_RS05410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CAURI_RS05420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAURI_RS05460	COG1556	Lactate utilization protein
CAURI_RS05465	COG1139	Iron-sulfur cluster binding protein
CAURI_RS05470	COG0247	lactate metabolic process
CAURI_RS05475	COG1620	l-lactate permease
CAURI_RS05490	COG1620	l-lactate permease
CAURI_RS05495	COG0018	arginyl-trna synthetase
CAURI_RS05500	COG0019	diaminopimelate decarboxylase activity
CAURI_RS05505	COG0460	homoserine dehydrogenase
CAURI_RS05510	COG0083	homoserine kinase activity
CAURI_RS05525	COG0725	ABC transporter, periplasmic molybdate-binding protein
CAURI_RS05545	COG0746	molybdenum cofactor guanylyltransferase activity
CAURI_RS05550	COG0315	cyclic pyranopterin monophosphate synthase activity
CAURI_RS05575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CAURI_RS05590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAURI_RS05600	COG0356	it plays a direct role in the translocation of protons across the membrane
CAURI_RS05605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAURI_RS05610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CAURI_RS05615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAURI_RS05620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CAURI_RS05625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAURI_RS05630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CAURI_RS05635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAURI_RS05645	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CAURI_RS05660	COG0747	negative chemotaxis
CAURI_RS05665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAURI_RS05675	COG0366	Alpha amylase catalytic
CAURI_RS05680	COG1119	ATPase activity
CAURI_RS05700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CAURI_RS05710	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CAURI_RS05715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CAURI_RS05735	COG0482	sulfurtransferase activity
CAURI_RS05765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CAURI_RS05780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAURI_RS05800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAURI_RS05825	COG0205	6-phosphofructokinase activity
CAURI_RS05830	COG0569	domain protein
CAURI_RS05830	COG2985	domain, Protein
CAURI_RS05840	COG1064	alcohol dehydrogenase
CAURI_RS05845	COG3949	Membrane
CAURI_RS05855	COG0583	DNA-binding transcription factor activity
CAURI_RS05870	COG3547	Transposase (IS116 IS110 IS902 family)
CAURI_RS05885	COG5650	phosphatidylinositol metabolic process
CAURI_RS05890	COG0129	dihydroxy-acid dehydratase activity
CAURI_RS05900	COG0028	Belongs to the TPP enzyme family
CAURI_RS05910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAURI_RS05930	COG0473	3-isopropylmalate dehydrogenase activity
CAURI_RS05945	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAURI_RS05960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAURI_RS05965	COG1121	(ABC) transporter
CAURI_RS06045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAURI_RS06050	COG0066	3-isopropylmalate dehydratase activity
CAURI_RS06060	COG0406	alpha-ribazole phosphatase activity
CAURI_RS06060	COG0494	nUDIX hydrolase
CAURI_RS06065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CAURI_RS06070	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAURI_RS06080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CAURI_RS06085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CAURI_RS06090	COG1461	Dihydroxyacetone kinase
CAURI_RS06095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAURI_RS06100	COG0742	ribosomal rna small subunit methyltransferase
CAURI_RS06105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CAURI_RS06115	COG2326	polyphosphate kinase activity
CAURI_RS06140	COG1090	epimerase
CAURI_RS06150	COG0540	Belongs to the ATCase OTCase family
CAURI_RS06155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAURI_RS06160	COG0505	Belongs to the CarA family
CAURI_RS06165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAURI_RS06170	COG0284	orotidine-5'-phosphate decarboxylase activity
CAURI_RS06185	COG1758	RNA polymerase activity
CAURI_RS06195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CAURI_RS06205	COG0242	peptide deformylase activity
CAURI_RS06210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAURI_RS06240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CAURI_RS06250	COG0322	excinuclease ABC activity
CAURI_RS06255	COG1660	Displays ATPase and GTPase activities
CAURI_RS06265	COG1481	regulation of sporulation
CAURI_RS06270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAURI_RS06275	COG0126	phosphoglycerate kinase activity
CAURI_RS06280	COG0149	triose-phosphate isomerase activity
CAURI_RS06285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAURI_RS06305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAURI_RS06360	COG0396	ATPase activity
CAURI_RS06370	COG0822	iron-sulfur transferase activity
CAURI_RS06380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAURI_RS06380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAURI_RS06380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAURI_RS06385	COG0488	(ABC) transporter
CAURI_RS06420	COG2848	UPF0210 protein
CAURI_RS06425	COG3830	Belongs to the UPF0237 family
CAURI_RS06455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CAURI_RS06465	COG3883	PFAM NLP P60 protein
CAURI_RS06465	COG0791	NLP P60 protein
CAURI_RS06470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CAURI_RS06490	COG0398	Pfam SNARE associated Golgi protein
CAURI_RS06510	COG1881	PFAM PEBP family protein
CAURI_RS06515	COG0167	dihydroorotate dehydrogenase activity
CAURI_RS06525	COG1968	undecaprenyl-diphosphatase activity
CAURI_RS06530	COG0215	cysteine-tRNA ligase activity
CAURI_RS06540	COG0546	phosphoglycolate phosphatase activity
CAURI_RS06545	COG0140	phosphoribosyl-ATP diphosphatase activity
CAURI_RS06550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CAURI_RS06555	COG1027	Aspartate ammonia-lyase
CAURI_RS06560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CAURI_RS06575	COG1362	aminopeptidase activity
CAURI_RS06585	COG1222	aaa ATPase
CAURI_RS06590	COG4122	O-methyltransferase activity
CAURI_RS06600	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CAURI_RS06615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAURI_RS06620	COG0805	protein transport
CAURI_RS06640	COG0300	oxidoreductase activity
CAURI_RS06660	COG0463	Glycosyl transferase, family 2
CAURI_RS06665	COG3842	ATPase activity
CAURI_RS06715	COG0477	Major facilitator Superfamily
CAURI_RS06740	COG0352	thiamine-phosphate diphosphorylase activity
CAURI_RS06740	COG0351	phosphomethylpyrimidine kinase
CAURI_RS06740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CAURI_RS06750	COG0598	Magnesium transport protein CorA
CAURI_RS06760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CAURI_RS06775	COG0513	Belongs to the DEAD box helicase family
CAURI_RS06805	COG1716	ATPase activity
CAURI_RS06810	COG0653	protein targeting
CAURI_RS06820	COG3012	SEC-C Motif Domain Protein
CAURI_RS06860	COG1131	(ABC) transporter
CAURI_RS06870	COG4585	Histidine kinase
CAURI_RS06875	COG2197	response regulator
CAURI_RS06880	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CAURI_RS06885	COG1160	GTP binding
CAURI_RS06890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CAURI_RS06900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CAURI_RS06920	COG4974	Belongs to the 'phage' integrase family
CAURI_RS06925	COG0494	nUDIX hydrolase
CAURI_RS06945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CAURI_RS06955	COG0647	UMP catabolic process
CAURI_RS06980	COG2801	Transposase and inactivated derivatives
CAURI_RS06995	COG2801	Transposase and inactivated derivatives
CAURI_RS07010	COG2835	tetraacyldisaccharide 4'-kinase activity
CAURI_RS07020	COG2304	oxidoreductase activity
CAURI_RS07040	COG0165	Argininosuccinate lyase
CAURI_RS07045	COG0137	argininosuccinate synthase activity
CAURI_RS07050	COG1438	arginine binding
CAURI_RS07055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CAURI_RS07060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAURI_RS07070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CAURI_RS07075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAURI_RS07085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAURI_RS07085	COG0072	phenylalanine-tRNA ligase activity
CAURI_RS07095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAURI_RS07105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CAURI_RS07110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CAURI_RS07140	COG3973	AAA domain
CAURI_RS07175	COG0237	dephospho-CoA kinase activity
CAURI_RS07180	COG0539	negative regulation of cytoplasmic translation
CAURI_RS07215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAURI_RS07220	COG0765	amino acid transport
CAURI_RS07225	COG1126	abc transporter atp-binding protein
CAURI_RS07230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAURI_RS07235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAURI_RS07240	COG0006	proline dipeptidase activity
CAURI_RS07245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAURI_RS07255	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAURI_RS07260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CAURI_RS07270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAURI_RS07280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAURI_RS07300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CAURI_RS07330	COG1760	l-serine dehydratase
CAURI_RS07335	COG0124	histidyl-tRNA synthetase
CAURI_RS07340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAURI_RS07345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CAURI_RS07365	COG2323	membrane
CAURI_RS07370	COG0737	Belongs to the 5'-nucleotidase family
CAURI_RS07375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAURI_RS07390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAURI_RS07395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAURI_RS07405	COG2255	four-way junction helicase activity
CAURI_RS07410	COG0632	four-way junction helicase activity
CAURI_RS07415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CAURI_RS07420	COG0778	Nitroreductase
CAURI_RS07425	COG0217	transcriptional regulatory protein
CAURI_RS07430	COG1946	Acyl-CoA thioesterase
CAURI_RS07445	COG2801	Transposase and inactivated derivatives
CAURI_RS07460	COG0438	transferase activity, transferring glycosyl groups
CAURI_RS07465	COG1560	Kdo2-lipid A biosynthetic process
CAURI_RS07470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAURI_RS07480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAURI_RS07485	COG2837	iron assimilation
CAURI_RS07555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAURI_RS07560	COG3253	May function as heme-dependent peroxidase
CAURI_RS07570	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CAURI_RS07575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CAURI_RS07580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAURI_RS07625	COG1461	Dihydroxyacetone kinase
CAURI_RS07630	COG2376	Dihydroxyacetone kinase
CAURI_RS07635	COG1061	Type III restriction enzyme res subunit
CAURI_RS07665	COG1321	iron dependent repressor
CAURI_RS07670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAURI_RS07705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAURI_RS07710	COG0450	alkyl hydroperoxide reductase
CAURI_RS07725	COG1643	Atp-dependent helicase
CAURI_RS07730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAURI_RS07740	COG1349	DNA-binding transcription factor activity
CAURI_RS07745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAURI_RS07750	COG1105	Belongs to the carbohydrate kinase PfkB family
CAURI_RS07755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CAURI_RS07755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAURI_RS07755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAURI_RS07760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAURI_RS07765	COG2233	PERMEase
CAURI_RS07770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAURI_RS07785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CAURI_RS07800	COG1196	nuclear chromosome segregation
CAURI_RS07810	COG1902	pentaerythritol trinitrate reductase activity
CAURI_RS07825	COG1126	abc transporter atp-binding protein
CAURI_RS07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAURI_RS07835	COG0765	amino acid transport
CAURI_RS07840	COG0765	amino acid transport
CAURI_RS07845	COG2137	regulation of response to DNA damage stimulus
CAURI_RS07850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAURI_RS07865	COG1268	BioY protein
CAURI_RS07870	COG1122	ATPase activity
CAURI_RS07875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CAURI_RS07880	COG1842	Phage shock protein A
CAURI_RS07885	COG1396	sequence-specific DNA binding
CAURI_RS07895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAURI_RS07910	COG1674	ftsk spoiiie
CAURI_RS07920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CAURI_RS07925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAURI_RS07930	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CAURI_RS07935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CAURI_RS07955	COG1185	polyribonucleotide nucleotidyltransferase activity
CAURI_RS07960	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAURI_RS07975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CAURI_RS07980	COG2977	Belongs to the P-Pant transferase superfamily
CAURI_RS07985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAURI_RS07990	COG0534	Mate efflux family protein
CAURI_RS07995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CAURI_RS08000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CAURI_RS08005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CAURI_RS08020	COG0779	Required for maturation of 30S ribosomal subunits
CAURI_RS08035	COG0442	prolyl-tRNA aminoacylation
CAURI_RS08040	COG3022	response to hydroperoxide
CAURI_RS08055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CAURI_RS08060	COG0579	oxidoreductase
CAURI_RS08100	COG0768	penicillin binding
CAURI_RS08105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CAURI_RS08115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CAURI_RS08130	COG1131	(ABC) transporter
CAURI_RS08135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAURI_RS08145	COG0575	Belongs to the CDS family
CAURI_RS08150	COG0233	cytoplasmic translational termination
CAURI_RS08155	COG0528	UMP kinase activity
CAURI_RS08160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CAURI_RS08175	COG4974	Belongs to the 'phage' integrase family
CAURI_RS08190	COG0792	nuclease activity
CAURI_RS08200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAURI_RS08205	COG0681	Belongs to the peptidase S26 family
CAURI_RS08210	COG0681	Belongs to the peptidase S26 family
CAURI_RS08225	COG0352	thiamine-phosphate diphosphorylase activity
CAURI_RS08240	COG2022	thiamine diphosphate biosynthetic process
CAURI_RS08270	COG0336	Belongs to the RNA methyltransferase TrmD family
CAURI_RS08290	COG0228	four-way junction DNA binding
CAURI_RS08295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAURI_RS08295	COG2755	lipolytic protein G-D-S-L family
CAURI_RS08305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CAURI_RS08335	COG0651	ATP synthesis coupled electron transport
CAURI_RS08340	COG1006	Multisubunit Na H antiporter MnhC subunit
CAURI_RS08345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAURI_RS08345	COG2111	Na H antiporter
CAURI_RS08360	COG1254	Belongs to the acylphosphatase family
CAURI_RS08365	COG1115	amino acid carrier protein
CAURI_RS08370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAURI_RS08375	COG0571	ribonuclease III activity
CAURI_RS08395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAURI_RS08400	COG1929	Belongs to the glycerate kinase type-1 family
CAURI_RS08415	COG0058	SHG alpha-glucan phosphorylase activity
CAURI_RS08420	COG0469	pyruvate kinase activity
CAURI_RS08425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAURI_RS08445	COG0107	imidazoleglycerol-phosphate synthase activity
CAURI_RS08450	COG0483	inositol monophosphate 1-phosphatase activity
CAURI_RS08460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CAURI_RS08475	COG0131	Imidazoleglycerol-phosphate dehydratase
CAURI_RS08480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAURI_RS08485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAURI_RS08515	COG2176	DNA-directed DNA polymerase activity
CAURI_RS08540	COG1739	Uncharacterized protein family UPF0029
CAURI_RS08545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAURI_RS08570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAURI_RS08615	COG0252	asparaginase activity
CAURI_RS08635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CAURI_RS08650	COG3599	regulation of cell shape
CAURI_RS08660	COG1799	cell septum assembly
CAURI_RS08665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CAURI_RS08670	COG1496	oxidoreductase activity
CAURI_RS08675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CAURI_RS08680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAURI_RS08685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAURI_RS08690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CAURI_RS08705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAURI_RS08715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAURI_RS08720	COG0768	penicillin binding
CAURI_RS08730	COG0275	rRNA processing
CAURI_RS08745	COG1136	(ABC) transporter
CAURI_RS08770	COG0142	geranyltranstransferase activity
CAURI_RS08790	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CAURI_RS08810	COG1940	carbohydrate kinase activity
CAURI_RS08815	COG0438	transferase activity, transferring glycosyl groups
CAURI_RS08875	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CAURI_RS08880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAURI_RS08890	COG2066	Belongs to the glutaminase family
CAURI_RS08895	COG1335	isochorismatase
CAURI_RS08905	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAURI_RS08915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAURI_RS08915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAURI_RS08920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAURI_RS08925	COG0509	glycine decarboxylation via glycine cleavage system
CAURI_RS08930	COG0321	lipoyl(octanoyl) transferase activity
CAURI_RS08935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CAURI_RS08950	COG0174	glutamine synthetase
CAURI_RS08965	COG1120	ATPase activity
CAURI_RS09010	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CAURI_RS09015	COG2271	Major facilitator Superfamily
CAURI_RS09030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CAURI_RS09035	COG0174	glutamine synthetase
CAURI_RS09075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CAURI_RS09100	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CAURI_RS09105	COG2267	carboxylic ester hydrolase activity
CAURI_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAURI_RS09135	COG0668	transmembrane transport
CAURI_RS09145	COG2860	membrane
CAURI_RS09165	COG3311	Transcriptional regulator
CAURI_RS09185	COG4988	ABC transporter
CAURI_RS09270	COG2801	Transposase and inactivated derivatives
CAURI_RS09275	COG2963	transposase activity
CAURI_RS09285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CAURI_RS09295	COG1134	teichoic acid transport
CAURI_RS09305	COG0463	Glycosyl transferase, family 2
CAURI_RS09320	COG0438	transferase activity, transferring glycosyl groups
CAURI_RS09325	COG0297	glycogen (starch) synthase activity
CAURI_RS09345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CAURI_RS09400	COG0423	glycine-tRNA ligase activity
CAURI_RS09415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAURI_RS09420	COG1381	Involved in DNA repair and RecF pathway recombination
CAURI_RS09435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CAURI_RS09455	COG1420	regulation of RNA biosynthetic process
CAURI_RS09470	COG1253	flavin adenine dinucleotide binding
CAURI_RS09475	COG1253	flavin adenine dinucleotide binding
CAURI_RS09485	COG1022	Amp-dependent synthetase and ligase
CAURI_RS09500	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CAURI_RS09510	COG1132	(ABC) transporter
CAURI_RS09520	COG1114	Component of the transport system for branched-chain amino acids
CAURI_RS09525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAURI_RS09530	COG2186	Transcriptional regulator
CAURI_RS09535	COG0747	negative chemotaxis
CAURI_RS09550	COG4172	Belongs to the ABC transporter superfamily
CAURI_RS09560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAURI_RS09570	COG2197	response regulator
CAURI_RS09575	COG4585	Histidine kinase
CAURI_RS09595	COG1473	amidohydrolase
CAURI_RS09615	COG0481	GTPase activity
CAURI_RS09625	COG0268	Binds directly to 16S ribosomal RNA
CAURI_RS09665	COG1307	EDD domain protein, DegV family
CAURI_RS09670	COG0406	alpha-ribazole phosphatase activity
CAURI_RS09680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAURI_RS09710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAURI_RS09730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CAURI_RS09735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAURI_RS09740	COG1530	ribonuclease E activity
CAURI_RS09750	COG0798	PFAM Bile acid sodium symporter
CAURI_RS09755	COG0640	Transcriptional regulator
CAURI_RS09760	COG0105	UTP biosynthetic process
CAURI_RS09780	COG0285	dihydrofolate synthase activity
CAURI_RS09790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CAURI_RS09800	COG0039	L-malate dehydrogenase activity
CAURI_RS09810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAURI_RS09815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CAURI_RS09825	COG0295	cytidine deaminase activity
CAURI_RS09830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAURI_RS09835	COG2390	Transcriptional regulator
CAURI_RS09840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CAURI_RS09845	COG2814	Major facilitator Superfamily
CAURI_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
CAURI_RS09855	COG0740	serine-type endopeptidase activity
CAURI_RS09870	COG1780	Probably involved in ribonucleotide reductase function
CAURI_RS09875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAURI_RS09880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAURI_RS09885	COG0431	NADPH-dependent FMN reductase
CAURI_RS09890	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAURI_RS09965	COG0739	heme binding
CAURI_RS10110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAURI_RS10115	COG0756	dUTP diphosphatase activity
CAURI_RS10130	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CAURI_RS10225	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CAURI_RS10265	COG3723	Recombinational DNA repair protein, rece pathway
CAURI_RS10315	COG0739	heme binding
CAURI_RS10425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAURI_RS10430	COG1121	(ABC) transporter
CAURI_RS10460	COG0756	dUTP diphosphatase activity
CAURI_RS10650	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CAURI_RS10680	COG2188	Transcriptional regulator
CAURI_RS10685	COG0300	oxidoreductase activity
CAURI_RS10700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAURI_RS10705	COG0601	transmembrane transport
CAURI_RS10710	COG0747	negative chemotaxis
CAURI_RS10725	COG0668	transmembrane transport
CAURI_RS10735	COG0686	Belongs to the AlaDH PNT family
CAURI_RS10760	COG1276	copper resistance
CAURI_RS10765	COG0583	DNA-binding transcription factor activity
CAURI_RS10785	COG4221	oxidoreductase activity
CAURI_RS10790	COG1115	amino acid carrier protein
CAURI_RS10795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CAURI_RS10810	COG2094	Belongs to the DNA glycosylase MPG family
CAURI_RS10820	COG0045	succinate-CoA ligase (ADP-forming) activity
CAURI_RS10825	COG1376	ErfK ybiS ycfS ynhG family protein
CAURI_RS10850	COG1120	ATPase activity
CAURI_RS10855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS10860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAURI_RS10925	COG0747	negative chemotaxis
CAURI_RS10940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CAURI_RS10950	COG1882	Formate acetyltransferase
CAURI_RS10970	COG1349	DNA-binding transcription factor activity
CAURI_RS10995	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CAURI_RS11020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CAURI_RS11030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CAURI_RS11050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAURI_RS11055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAURI_RS11060	COG2186	Transcriptional regulator
CAURI_RS11065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAURI_RS11080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CAURI_RS11085	COG2814	Major facilitator Superfamily
CAURI_RS11090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CAURI_RS11130	COG0033	Phosphoglucomutase
CAURI_RS11135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAURI_RS11140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAURI_RS11145	COG1136	(ABC) transporter
CAURI_RS11145	COG0577	efflux transmembrane transporter activity
CAURI_RS11150	COG0577	efflux transmembrane transporter activity
CAURI_RS11150	COG1136	(ABC) transporter
CAURI_RS11170	COG2239	Acts as a magnesium transporter
CAURI_RS11185	COG4584	PFAM Integrase catalytic
CAURI_RS11185	COG2390	Transcriptional regulator
CAURI_RS11200	COG2801	Transposase and inactivated derivatives
CAURI_RS11205	COG2963	transposase activity
CAURI_RS11210	COG2801	Transposase and inactivated derivatives
CAURI_RS11235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAURI_RS11240	COG2197	response regulator
CAURI_RS11245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CAURI_RS11250	COG1045	serine acetyltransferase
CAURI_RS11280	COG1937	Protein conserved in bacteria
CAURI_RS11305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAURI_RS11325	COG0456	acetyltransferase
CAURI_RS11335	COG1597	lipid kinase activity
CAURI_RS11360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAURI_RS11380	COG2030	dehydratase
CAURI_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
CAURI_RS11390	COG0183	Belongs to the thiolase family
CAURI_RS11405	COG1272	protein, Hemolysin III
CAURI_RS11420	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAURI_RS11425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAURI_RS11435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAURI_RS11440	COG0047	phosphoribosylformylglycinamidine synthase activity
CAURI_RS11445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAURI_RS11480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CAURI_RS11495	COG2205	protein histidine kinase activity
CAURI_RS11500	COG0745	RESPONSE REGULATOR receiver
CAURI_RS11505	COG0789	Transcriptional regulator
CAURI_RS11505	COG4978	Transcriptional regulator
CAURI_RS11515	COG0028	Belongs to the TPP enzyme family
CAURI_RS11520	COG0477	Major facilitator Superfamily
CAURI_RS11525	COG2801	Transposase and inactivated derivatives
CAURI_RS11555	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CAURI_RS11565	COG1877	trehalose-phosphatase activity
CAURI_RS11570	COG1609	Transcriptional regulator
CAURI_RS11580	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CAURI_RS11580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CAURI_RS11585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAURI_RS11600	COG1129	ABC transporter
CAURI_RS11605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAURI_RS11630	COG2847	Copper chaperone PCu(A)C
CAURI_RS11635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CAURI_RS11650	COG1194	a g-specific adenine glycosylase
CAURI_RS11685	COG0542	response to heat
CAURI_RS11695	COG0477	Major facilitator Superfamily
CAURI_RS11705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CAURI_RS11720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CAURI_RS11740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAURI_RS11755	COG0302	gtp cyclohydrolase
CAURI_RS11760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAURI_RS11775	COG2027	D-alanyl-D-alanine carboxypeptidase
CAURI_RS11780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CAURI_RS11800	COG1136	(ABC) transporter
CAURI_RS11820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAURI_RS11840	COG2326	polyphosphate kinase activity
CAURI_RS11855	COG1297	OPT oligopeptide transporter protein
CAURI_RS11865	COG2111	Na H antiporter
CAURI_RS11865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAURI_RS11870	COG1006	Multisubunit Na H antiporter MnhC subunit
CAURI_RS11875	COG0651	ATP synthesis coupled electron transport
CAURI_RS11885	COG2212	antiporter activity
CAURI_RS11895	COG1051	belongs to the nudix hydrolase family
CAURI_RS11915	COG0242	peptide deformylase activity
CAURI_RS11935	COG2814	Major facilitator Superfamily
CAURI_RS11945	COG1131	(ABC) transporter
CAURI_RS11960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAURI_RS11970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAURI_RS11975	COG0280	phosphate acetyltransferase
CAURI_RS11985	COG3711	transcriptional antiterminator
CAURI_RS12010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAURI_RS12030	COG4129	membrane
CAURI_RS12035	COG0471	metal ion transport
CAURI_RS12040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CAURI_RS12055	COG0191	fructose-bisphosphate aldolase activity
CAURI_RS12070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAURI_RS12105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAURI_RS12120	COG0789	Transcriptional regulator
CAURI_RS12135	COG0443	Heat shock 70 kDa protein
CAURI_RS12140	COG1120	ATPase activity
CAURI_RS12145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAURI_RS12155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAURI_RS12160	COG1012	belongs to the aldehyde dehydrogenase family
CAURI_RS12170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAURI_RS12205	COG0175	sulfate reduction
CAURI_RS12225	COG2181	nitrate reductase activity
CAURI_RS12225	COG0247	lactate metabolic process
CAURI_RS12255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CAURI_RS12280	COG1132	(ABC) transporter
CAURI_RS12290	COG1472	Belongs to the glycosyl hydrolase 3 family
CAURI_RS12305	COG4981	capsule polysaccharide biosynthetic process
CAURI_RS12325	COG0297	glycogen (starch) synthase activity
CAURI_RS12335	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CAURI_RS12370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAURI_RS12375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAURI_RS12375	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CAURI_RS12375	COG3321	synthase
CAURI_RS12380	COG0318	PFAM AMP-dependent synthetase and ligase
CAURI_RS12385	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CAURI_RS12395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CAURI_RS12395	COG5479	isomerase activity
CAURI_RS12405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAURI_RS12410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CAURI_RS12420	COG1216	Glycosyl transferase, family 2
CAURI_RS12465	COG2801	Transposase and inactivated derivatives
CAURI_RS12470	COG0561	phosphatase activity
CAURI_RS12475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CAURI_RS12480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CAURI_RS12485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CAURI_RS12495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CAURI_RS12500	COG2188	Transcriptional regulator
CAURI_RS12520	COG0077	Prephenate dehydratase
CAURI_RS12535	COG1316	TRANSCRIPTIONal
CAURI_RS12545	COG0584	glycerophosphoryl diester phosphodiesterase
CAURI_RS12560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAURI_RS12570	COG1966	Carbon starvation protein
CAURI_RS12585	COG0583	DNA-binding transcription factor activity
CAURI_RS12590	COG2814	Major facilitator Superfamily
CAURI_RS12615	COG2197	response regulator
CAURI_RS12620	COG2203	Gaf domain
CAURI_RS12620	COG4585	Histidine kinase
CAURI_RS12635	COG3764	Sortase (surface protein transpeptidase)
CAURI_RS12640	COG0706	membrane insertase activity
CAURI_RS12660	COG0564	pseudouridine synthase activity
CAURI_RS12690	COG1131	(ABC) transporter
CAURI_RS12705	COG1842	Phage shock protein A
CAURI_RS12710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAURI_RS12725	COG0477	Major facilitator Superfamily
CAURI_RS12735	COG0305	Participates in initiation and elongation during chromosome replication
CAURI_RS12740	COG0359	binds to the 23S rRNA
CAURI_RS12750	COG0360	Binds together with S18 to 16S ribosomal RNA
CAURI_RS12765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAURI_RS12775	COG1846	Transcriptional regulator
CAURI_RS12790	COG1054	Belongs to the UPF0176 family
CAURI_RS12795	COG4868	Belongs to the UPF0371 family
CAURI_RS12815	COG1136	(ABC) transporter
CAURI_RS12820	COG0577	efflux transmembrane transporter activity
CAURI_RS12825	COG4585	Histidine kinase
CAURI_RS12830	COG2197	response regulator
CAURI_RS12845	COG0604	alcohol dehydrogenase
CAURI_RS12855	COG0733	neurotransmitter:sodium symporter activity
CAURI_RS12860	COG3573	Dehydrogenase
CAURI_RS12880	COG2801	Transposase and inactivated derivatives
CAURI_RS12895	COG0495	leucyl-tRNA aminoacylation
CAURI_RS12900	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CAURI_RS12905	COG3311	Transcriptional regulator
CAURI_RS12910	COG1715	Restriction endonuclease
CAURI_RS12960	COG3177	Filamentation induced by cAMP protein fic
CAURI_RS13000	COG1012	belongs to the aldehyde dehydrogenase family
CAURI_RS13030	COG3971	2-oxopent-4-enoate hydratase activity
CAURI_RS13040	COG1012	belongs to the aldehyde dehydrogenase family
CAURI_RS13045	COG1802	Transcriptional regulator
CAURI_RS13055	COG0477	Major facilitator Superfamily
CAURI_RS13065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAURI_RS13065	COG1116	anion transmembrane transporter activity
CAURI_RS13080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CAURI_RS13085	COG0512	Glutamine amidotransferase of anthranilate synthase
CAURI_RS13090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CAURI_RS13095	COG0135	phosphoribosylanthranilate isomerase activity
CAURI_RS13095	COG0134	indole-3-glycerol-phosphate synthase activity
CAURI_RS13105	COG0159	tryptophan synthase activity
CAURI_RS13115	COG4584	PFAM Integrase catalytic
CAURI_RS13115	COG2390	Transcriptional regulator
CAURI_RS13120	COG1484	DNA-dependent DNA replication
CAURI_RS13160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CAURI_RS13165	COG1678	Uncharacterized ACR, COG1678
CAURI_RS13170	COG0617	tRNA 3'-terminal CCA addition
CAURI_RS13190	COG2353	YceI-like domain
CAURI_RS13210	COG3118	belongs to the thioredoxin family
CAURI_RS13215	COG3409	Peptidoglycan-binding domain 1 protein
CAURI_RS13215	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAURI_RS13230	COG1192	Involved in chromosome partitioning
CAURI_RS13245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAURI_RS13250	COG0594	ribonuclease P activity
CAURI_RS13255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CAURI_RS13295	COG2801	Transposase and inactivated derivatives
CAURI_RS13375	COG2755	lipolytic protein G-D-S-L family
CAURI_RS13375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups