locus-tag	class	description
CCASEI_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCASEI_RS00020	COG0592	DNA-directed DNA polymerase activity
CCASEI_RS00065	COG3328	transposase activity
CCASEI_RS00095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CCASEI_RS00255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCASEI_RS00435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCASEI_RS00525	COG3328	transposase activity
CCASEI_RS00575	COG2217	Heavy metal translocating P-type atpase
CCASEI_RS00760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCASEI_RS00775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCASEI_RS01480	COG2801	Transposase and inactivated derivatives
CCASEI_RS01935	COG0747	negative chemotaxis
CCASEI_RS02085	COG1088	dTDP-glucose 4,6-dehydratase activity
CCASEI_RS02310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCASEI_RS02335	COG1648	precorrin-2 dehydrogenase activity
CCASEI_RS02335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCASEI_RS02385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCASEI_RS02700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCASEI_RS02825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCASEI_RS03275	COG4988	ABC transporter
CCASEI_RS03320	COG2873	o-acetylhomoserine
CCASEI_RS03485	COG2079	MmgE PrpD family protein
CCASEI_RS03605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCASEI_RS03740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCASEI_RS03795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CCASEI_RS03805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCASEI_RS04075	COG1012	belongs to the aldehyde dehydrogenase family
CCASEI_RS04425	COG1022	Amp-dependent synthetase and ligase
CCASEI_RS05170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCASEI_RS05370	COG1940	carbohydrate kinase activity
CCASEI_RS05525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCASEI_RS05640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCASEI_RS05750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCASEI_RS05770	COG0058	SHG alpha-glucan phosphorylase activity
CCASEI_RS05800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCASEI_RS05820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCASEI_RS05830	COG1196	nuclear chromosome segregation
CCASEI_RS05850	COG2111	Na H antiporter
CCASEI_RS05965	COG0681	Belongs to the peptidase S26 family
CCASEI_RS06135	COG0442	prolyl-tRNA aminoacylation
CCASEI_RS06155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCASEI_RS06210	COG1185	polyribonucleotide nucleotidyltransferase activity
CCASEI_RS06240	COG1674	ftsk spoiiie
CCASEI_RS06260	COG0861	Integral membrane protein TerC family
CCASEI_RS06315	COG0765	amino acid transport
CCASEI_RS06375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCASEI_RS06430	COG1643	Atp-dependent helicase
CCASEI_RS06685	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCASEI_RS06770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCASEI_RS06910	COG0006	proline dipeptidase activity
CCASEI_RS06995	COG0653	protein targeting
CCASEI_RS07000	COG0653	protein targeting
CCASEI_RS07780	COG0165	Argininosuccinate lyase
CCASEI_RS08615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCASEI_RS09080	COG0747	negative chemotaxis
CCASEI_RS09170	COG1823	symporter activity
CCASEI_RS09420	COG2315	Protein conserved in bacteria
CCASEI_RS09515	COG0114	fumarate hydratase activity
CCASEI_RS09645	COG0148	phosphopyruvate hydratase activity
CCASEI_RS09865	COG0488	(ABC) transporter
CCASEI_RS10210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCASEI_RS10250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCASEI_RS10705	COG0653	protein targeting
CCASEI_RS10725	COG5401	PFAM Sporulation and spore germination
CCASEI_RS10995	COG3104	oligopeptide transport
CCASEI_RS11030	COG3328	transposase activity
CCASEI_RS11495	COG0515	serine threonine protein kinase
CCASEI_RS11535	COG0587	DNA-directed DNA polymerase activity
CCASEI_RS11655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCASEI_RS11785	COG0477	Major facilitator Superfamily
CCASEI_RS11795	COG4335	DNA alkylation repair
CCASEI_RS12595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCASEI_RS12600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCASEI_RS12680	COG2111	Na H antiporter
CCASEI_RS12680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCASEI_RS12700	COG0651	ATP synthesis coupled electron transport
CCASEI_RS13195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CCASEI_RS13290	COG1984	allophanate hydrolase subunit 2
CCASEI_RS13440	COG2814	Major facilitator Superfamily
CCASEI_RS14225	COG0187	DNA topoisomerase II activity
CCASEI_RS14400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCASEI_RS14410	COG0647	UMP catabolic process