locus-tag	class	description
CGLAR1_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGLAR1_RS00010	COG0592	DNA-directed DNA polymerase activity
CGLAR1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGLAR1_RS00025	COG0187	DNA topoisomerase II activity
CGLAR1_RS00080	COG2855	membrane
CGLAR1_RS00085	COG0583	DNA-binding transcription factor activity
CGLAR1_RS00100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CGLAR1_RS00100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CGLAR1_RS00140	COG1764	response to oxidative stress
CGLAR1_RS00155	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGLAR1_RS00165	COG1121	(ABC) transporter
CGLAR1_RS00175	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGLAR1_RS00180	COG1129	ABC transporter
CGLAR1_RS00220	COG2815	serine threonine protein kinase
CGLAR1_RS00220	COG0515	serine threonine protein kinase
CGLAR1_RS00225	COG0515	serine threonine protein kinase
CGLAR1_RS00230	COG0768	penicillin binding
CGLAR1_RS00250	COG1716	ATPase activity
CGLAR1_RS00350	COG2801	Transposase and inactivated derivatives
CGLAR1_RS00360	COG2801	Transposase and inactivated derivatives
CGLAR1_RS00510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGLAR1_RS00515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGLAR1_RS00520	COG1937	Protein conserved in bacteria
CGLAR1_RS00565	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CGLAR1_RS00575	COG2851	Citrate transporter
CGLAR1_RS00580	COG3290	protein histidine kinase activity
CGLAR1_RS00585	COG4565	transcriptional regulatory protein
CGLAR1_RS00590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGLAR1_RS00600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGLAR1_RS00640	COG0402	S-adenosylhomocysteine deaminase activity
CGLAR1_RS00655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CGLAR1_RS00690	COG0804	urea catabolic process
CGLAR1_RS00700	COG0830	nickel cation binding
CGLAR1_RS00705	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CGLAR1_RS00710	COG0829	nickel cation binding
CGLAR1_RS00715	COG2814	Major facilitator Superfamily
CGLAR1_RS00725	COG0326	Molecular chaperone. Has ATPase activity
CGLAR1_RS00730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGLAR1_RS00745	COG1012	belongs to the aldehyde dehydrogenase family
CGLAR1_RS00750	COG0667	Aldo Keto reductase
CGLAR1_RS00755	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CGLAR1_RS00765	COG2149	membrane
CGLAR1_RS00790	COG0346	lactoylglutathione lyase activity
CGLAR1_RS00810	COG2814	Major facilitator Superfamily
CGLAR1_RS00820	COG1070	Carbohydrate kinase
CGLAR1_RS00825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGLAR1_RS00835	COG3177	Filamentation induced by cAMP protein fic
CGLAR1_RS00850	COG0657	acetylesterase activity
CGLAR1_RS00860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGLAR1_RS00915	COG2860	membrane
CGLAR1_RS00935	COG3180	Ammonia monooxygenase
CGLAR1_RS00945	COG0730	response to heat
CGLAR1_RS00955	COG1643	Atp-dependent helicase
CGLAR1_RS00960	COG0110	maltose O-acetyltransferase activity
CGLAR1_RS00970	COG2818	Glycosylase
CGLAR1_RS00975	COG1280	lysine exporter protein (LysE YggA)
CGLAR1_RS01005	COG0251	oxidation-reduction process
CGLAR1_RS01015	COG3590	peptidase
CGLAR1_RS01030	COG2188	Transcriptional regulator
CGLAR1_RS01035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGLAR1_RS01050	COG3718	enzyme involved in inositol metabolism
CGLAR1_RS01055	COG3962	Belongs to the TPP enzyme family
CGLAR1_RS01065	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS01070	COG1082	Xylose isomerase domain protein TIM barrel
CGLAR1_RS01100	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS01120	COG1278	Cold shock
CGLAR1_RS01145	COG1609	Transcriptional regulator
CGLAR1_RS01155	COG2814	Major facilitator Superfamily
CGLAR1_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
CGLAR1_RS01195	COG0277	FAD linked oxidase domain protein
CGLAR1_RS01230	COG2258	MOSC domain
CGLAR1_RS01235	COG1216	Glycosyl transferase, family 2
CGLAR1_RS01280	COG1115	amino acid carrier protein
CGLAR1_RS01305	COG0315	cyclic pyranopterin monophosphate synthase activity
CGLAR1_RS01305	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGLAR1_RS01325	COG0725	ABC transporter, periplasmic molybdate-binding protein
CGLAR1_RS01335	COG3842	ATPase activity
CGLAR1_RS01340	COG1950	PFAM Membrane protein of
CGLAR1_RS01345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGLAR1_RS01360	COG2239	Acts as a magnesium transporter
CGLAR1_RS01365	COG0471	metal ion transport
CGLAR1_RS01375	COG0287	Prephenate dehydrogenase
CGLAR1_RS01390	COG3237	CsbD-like
CGLAR1_RS01405	COG2409	Drug exporters of the RND superfamily
CGLAR1_RS01410	COG0343	queuine tRNA-ribosyltransferase activity
CGLAR1_RS01430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGLAR1_RS01445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGLAR1_RS01470	COG3442	glutamine amidotransferase
CGLAR1_RS01475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CGLAR1_RS01495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGLAR1_RS01500	COG0697	spore germination
CGLAR1_RS01505	COG0527	aspartate kinase activity
CGLAR1_RS01540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CGLAR1_RS01565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGLAR1_RS01585	COG0651	ATP synthesis coupled electron transport
CGLAR1_RS01590	COG1006	Multisubunit Na H antiporter MnhC subunit
CGLAR1_RS01595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGLAR1_RS01595	COG2111	Na H antiporter
CGLAR1_RS01610	COG0745	RESPONSE REGULATOR receiver
CGLAR1_RS01615	COG3850	Histidine kinase
CGLAR1_RS01615	COG5002	protein histidine kinase activity
CGLAR1_RS01645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGLAR1_RS01670	COG0477	Major facilitator Superfamily
CGLAR1_RS01680	COG1846	Transcriptional regulator
CGLAR1_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
CGLAR1_RS01695	COG1960	acyl-CoA dehydrogenase activity
CGLAR1_RS01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGLAR1_RS01710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGLAR1_RS01725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGLAR1_RS01790	COG1111	helicase
CGLAR1_RS01790	COG1205	dead DEAH box helicase
CGLAR1_RS01795	COG1278	Cold shock
CGLAR1_RS01800	COG1754	DNA topoisomerase type I activity
CGLAR1_RS01800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGLAR1_RS01900	COG0564	pseudouridine synthase activity
CGLAR1_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
CGLAR1_RS01960	COG0737	Belongs to the 5'-nucleotidase family
CGLAR1_RS01960	COG1525	nuclease
CGLAR1_RS01960	COG4085	toxin activity
CGLAR1_RS01965	COG1064	alcohol dehydrogenase
CGLAR1_RS01980	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGLAR1_RS01990	COG1088	dTDP-glucose 4,6-dehydratase activity
CGLAR1_RS01995	COG0778	Nitroreductase
CGLAR1_RS02000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGLAR1_RS02020	COG1505	serine-type exopeptidase activity
CGLAR1_RS02065	COG3547	Transposase (IS116 IS110 IS902 family)
CGLAR1_RS02100	COG1134	teichoic acid transport
CGLAR1_RS02130	COG0438	transferase activity, transferring glycosyl groups
CGLAR1_RS02140	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS02145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGLAR1_RS02150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGLAR1_RS02160	COG3800	Transcriptional regulator
CGLAR1_RS02160	COG1396	sequence-specific DNA binding
CGLAR1_RS02170	COG1053	succinate dehydrogenase
CGLAR1_RS02175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGLAR1_RS02215	COG2733	membrane
CGLAR1_RS02230	COG1309	transcriptional regulator
CGLAR1_RS02245	COG0788	formyltetrahydrofolate deformylase activity
CGLAR1_RS02250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGLAR1_RS02260	COG1937	Protein conserved in bacteria
CGLAR1_RS02280	COG4558	Periplasmic binding protein
CGLAR1_RS02285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS02290	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CGLAR1_RS02320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CGLAR1_RS02330	COG0318	PFAM AMP-dependent synthetase and ligase
CGLAR1_RS02345	COG5002	protein histidine kinase activity
CGLAR1_RS02350	COG0745	RESPONSE REGULATOR receiver
CGLAR1_RS02360	COG0577	efflux transmembrane transporter activity
CGLAR1_RS02380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGLAR1_RS02400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CGLAR1_RS02405	COG0181	hydroxymethylbilane synthase activity
CGLAR1_RS02420	COG0477	Major facilitator Superfamily
CGLAR1_RS02425	COG1082	Xylose isomerase domain protein TIM barrel
CGLAR1_RS02425	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CGLAR1_RS02430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CGLAR1_RS02440	COG0222	ribosome binding
CGLAR1_RS02445	COG3842	ATPase activity
CGLAR1_RS02460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGLAR1_RS02460	COG1648	precorrin-2 dehydrogenase activity
CGLAR1_RS02470	COG0113	porphobilinogen synthase activity
CGLAR1_RS02485	COG2217	Heavy metal translocating P-type atpase
CGLAR1_RS02500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CGLAR1_RS02505	COG0406	alpha-ribazole phosphatase activity
CGLAR1_RS02515	COG0785	Cytochrome C biogenesis protein
CGLAR1_RS02520	COG1333	cytochrome c biogenesis protein
CGLAR1_RS02525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGLAR1_RS02580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGLAR1_RS02585	COG0583	DNA-binding transcription factor activity
CGLAR1_RS02625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGLAR1_RS02630	COG2154	pterin-4-alpha-carbinolamine dehydratase
CGLAR1_RS02635	COG3340	Belongs to the peptidase S51 family
CGLAR1_RS02640	COG4948	Mandelate Racemase Muconate Lactonizing
CGLAR1_RS02655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGLAR1_RS02655	COG0438	transferase activity, transferring glycosyl groups
CGLAR1_RS02660	COG1113	amino acid transport
CGLAR1_RS02675	COG0142	geranyltranstransferase activity
CGLAR1_RS02715	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGLAR1_RS02775	COG0085	RNA polymerase activity
CGLAR1_RS02810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGLAR1_RS02820	COG2826	transposase and inactivated derivatives, IS30 family
CGLAR1_RS02830	COG1120	ATPase activity
CGLAR1_RS02835	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS02840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS02860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGLAR1_RS02950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CGLAR1_RS02975	COG3845	ABC transporter
CGLAR1_RS03010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CGLAR1_RS03020	COG1841	ribosomal large subunit assembly
CGLAR1_RS03050	COG3396	Phenylacetate-CoA oxygenase
CGLAR1_RS03055	COG3460	Phenylacetate-CoA oxygenase
CGLAR1_RS03060	COG3396	Phenylacetate-CoA oxygenase
CGLAR1_RS03065	COG2151	metal-sulfur cluster biosynthetic enzyme
CGLAR1_RS03070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGLAR1_RS03075	COG1024	Enoyl-CoA hydratase
CGLAR1_RS03085	COG1024	Enoyl-CoA hydratase
CGLAR1_RS03090	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGLAR1_RS03095	COG2050	protein possibly involved in aromatic compounds catabolism
CGLAR1_RS03100	COG1012	belongs to the aldehyde dehydrogenase family
CGLAR1_RS03100	COG2030	dehydratase
CGLAR1_RS03135	COG3848	Pyruvate phosphate dikinase
CGLAR1_RS03135	COG0574	Belongs to the PEP-utilizing enzyme family
CGLAR1_RS03150	COG1414	Transcriptional regulator
CGLAR1_RS03155	COG0201	protein transport
CGLAR1_RS03190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGLAR1_RS03195	COG0202	RNA polymerase activity
CGLAR1_RS03200	COG0203	ribosomal protein L17
CGLAR1_RS03205	COG0101	tRNA pseudouridine synthase activity
CGLAR1_RS03230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CGLAR1_RS03240	COG1404	Belongs to the peptidase S8 family
CGLAR1_RS03250	COG1674	ftsk spoiiie
CGLAR1_RS03280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGLAR1_RS03315	COG2985	domain, Protein
CGLAR1_RS03315	COG0569	domain protein
CGLAR1_RS03330	COG0456	acetyltransferase
CGLAR1_RS03340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CGLAR1_RS03340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CGLAR1_RS03355	COG0459	protein refolding
CGLAR1_RS03385	COG0516	GMP reductase activity
CGLAR1_RS03395	COG0583	DNA-binding transcription factor activity
CGLAR1_RS03400	COG0519	Catalyzes the synthesis of GMP from XMP
CGLAR1_RS03400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CGLAR1_RS03420	COG2197	response regulator
CGLAR1_RS03445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGLAR1_RS03485	COG2409	Drug exporters of the RND superfamily
CGLAR1_RS03505	COG0702	epimerase
CGLAR1_RS03510	COG0415	Belongs to the DNA photolyase family
CGLAR1_RS03515	COG1216	Glycosyl transferase, family 2
CGLAR1_RS03525	COG0577	efflux transmembrane transporter activity
CGLAR1_RS03525	COG1136	(ABC) transporter
CGLAR1_RS03530	COG2011	ABC-type metal ion transport system permease component
CGLAR1_RS03535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CGLAR1_RS03540	COG1464	Belongs to the NlpA lipoprotein family
CGLAR1_RS03545	COG0587	DNA-directed DNA polymerase activity
CGLAR1_RS03570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CGLAR1_RS03580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGLAR1_RS03585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CGLAR1_RS03610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGLAR1_RS03615	COG2873	o-acetylhomoserine
CGLAR1_RS03620	COG1966	Carbon starvation protein
CGLAR1_RS03630	COG2079	MmgE PrpD family protein
CGLAR1_RS03635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGLAR1_RS03640	COG0372	Belongs to the citrate synthase family
CGLAR1_RS03665	COG2838	Isocitrate dehydrogenase
CGLAR1_RS03675	COG1120	ATPase activity
CGLAR1_RS03680	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS03695	COG2814	Major facilitator Superfamily
CGLAR1_RS03705	COG2860	membrane
CGLAR1_RS03720	COG1120	ATPase activity
CGLAR1_RS03725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS03730	COG0180	Tryptophanyl-tRNA synthetase
CGLAR1_RS03735	COG1295	ribonuclease BN
CGLAR1_RS03745	COG1686	Belongs to the peptidase S11 family
CGLAR1_RS03755	COG0791	NLP P60 protein
CGLAR1_RS03755	COG0741	lytic transglycosylase activity
CGLAR1_RS03775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGLAR1_RS03780	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGLAR1_RS03780	COG1473	amidohydrolase
CGLAR1_RS03790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CGLAR1_RS03805	COG0523	cobalamin synthesis protein
CGLAR1_RS03810	COG0492	ferredoxin-NADP+ reductase activity
CGLAR1_RS03815	COG2079	MmgE PrpD family protein
CGLAR1_RS03820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGLAR1_RS03825	COG0372	Belongs to the citrate synthase family
CGLAR1_RS03835	COG3800	Transcriptional regulator
CGLAR1_RS03835	COG1396	sequence-specific DNA binding
CGLAR1_RS03845	COG4770	biotin carboxylase activity
CGLAR1_RS03850	COG2897	thiosulfate sulfurtransferase activity
CGLAR1_RS03855	COG0189	ligase activity
CGLAR1_RS03870	COG0424	maF-like protein
CGLAR1_RS03880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGLAR1_RS03885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGLAR1_RS03930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGLAR1_RS03980	COG3842	ATPase activity
CGLAR1_RS04005	COG0210	DNA helicase
CGLAR1_RS04010	COG1201	RNA secondary structure unwinding
CGLAR1_RS04020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGLAR1_RS04025	COG1316	TRANSCRIPTIONal
CGLAR1_RS04065	COG1482	cell wall glycoprotein biosynthetic process
CGLAR1_RS04090	COG0745	RESPONSE REGULATOR receiver
CGLAR1_RS04095	COG5002	protein histidine kinase activity
CGLAR1_RS04100	COG5401	PFAM Sporulation and spore germination
CGLAR1_RS04110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGLAR1_RS04115	COG0653	protein targeting
CGLAR1_RS04125	COG1011	Hydrolase
CGLAR1_RS04135	COG1162	GTPase activity
CGLAR1_RS04140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CGLAR1_RS04175	COG0513	Belongs to the DEAD box helicase family
CGLAR1_RS04200	COG0210	DNA helicase
CGLAR1_RS04205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGLAR1_RS04210	COG2816	NAD+ diphosphatase activity
CGLAR1_RS04235	COG3480	Lon protease (S16) C-terminal proteolytic domain
CGLAR1_RS04250	COG1615	UPF0182 protein
CGLAR1_RS04255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGLAR1_RS04260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGLAR1_RS04265	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CGLAR1_RS04285	COG0483	inositol monophosphate 1-phosphatase activity
CGLAR1_RS04290	COG0483	inositol monophosphate 1-phosphatase activity
CGLAR1_RS04300	COG2884	Cell division ATP-binding protein ftsE
CGLAR1_RS04305	COG2177	Part of the ABC transporter FtsEX involved in
CGLAR1_RS04315	COG3189	MarR family transcriptional regulator
CGLAR1_RS04325	COG1132	(ABC) transporter
CGLAR1_RS04325	COG2375	cellular response to nickel ion
CGLAR1_RS04330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGLAR1_RS04385	COG1061	Type III restriction enzyme res subunit
CGLAR1_RS04400	COG1652	LysM domain
CGLAR1_RS04405	COG1278	Cold shock
CGLAR1_RS04425	COG2252	PERMEase
CGLAR1_RS04430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGLAR1_RS04450	COG0372	Belongs to the citrate synthase family
CGLAR1_RS04455	COG0545	Peptidyl-prolyl cis-trans isomerase
CGLAR1_RS04470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGLAR1_RS04480	COG3757	hydrolase, family 25
CGLAR1_RS04485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CGLAR1_RS04520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CGLAR1_RS04535	COG1218	3'(2'),5'-bisphosphate nucleotidase
CGLAR1_RS04540	COG1201	RNA secondary structure unwinding
CGLAR1_RS04545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGLAR1_RS04550	COG3304	Inner membrane component domain
CGLAR1_RS04555	COG0586	Pfam SNARE associated Golgi protein
CGLAR1_RS04565	COG0166	Belongs to the GPI family
CGLAR1_RS04575	COG1605	Chorismate mutase
CGLAR1_RS04590	COG1136	(ABC) transporter
CGLAR1_RS04590	COG0577	efflux transmembrane transporter activity
CGLAR1_RS04600	COG0739	heme binding
CGLAR1_RS04620	COG0138	bifunctional purine biosynthesis protein purh
CGLAR1_RS04660	COG0659	secondary active sulfate transmembrane transporter activity
CGLAR1_RS04680	COG0745	RESPONSE REGULATOR receiver
CGLAR1_RS04690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGLAR1_RS04710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGLAR1_RS04715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGLAR1_RS04735	COG2807	transmembrane transport
CGLAR1_RS04755	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CGLAR1_RS04765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGLAR1_RS04770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGLAR1_RS04780	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CGLAR1_RS04790	COG0657	acetylesterase activity
CGLAR1_RS04800	COG2801	Transposase and inactivated derivatives
CGLAR1_RS04810	COG0277	FAD linked oxidase domain protein
CGLAR1_RS04830	COG2801	Transposase and inactivated derivatives
CGLAR1_RS04845	COG0084	hydrolase, TatD family'
CGLAR1_RS04850	COG3583	domain protein
CGLAR1_RS04865	COG0488	(ABC) transporter
CGLAR1_RS04890	COG2326	polyphosphate kinase activity
CGLAR1_RS04895	COG0561	phosphatase activity
CGLAR1_RS04925	COG2409	Drug exporters of the RND superfamily
CGLAR1_RS04930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGLAR1_RS04950	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CGLAR1_RS04970	COG0411	ABC transporter
CGLAR1_RS04980	COG0193	aminoacyl-tRNA hydrolase activity
CGLAR1_RS04995	COG0193	aminoacyl-tRNA hydrolase activity
CGLAR1_RS05000	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGLAR1_RS05015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGLAR1_RS05020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGLAR1_RS05035	COG1131	(ABC) transporter
CGLAR1_RS05045	COG4585	Histidine kinase
CGLAR1_RS05050	COG2201	protein-glutamate methylesterase activity
CGLAR1_RS05065	COG1132	(ABC) transporter
CGLAR1_RS05070	COG1132	(ABC) transporter
CGLAR1_RS05075	COG0405	Gamma-glutamyltransferase
CGLAR1_RS05090	COG1309	transcriptional regulator
CGLAR1_RS05110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGLAR1_RS05115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGLAR1_RS05120	COG0531	amino acid
CGLAR1_RS05130	COG3956	TIGRFAM MazG family protein
CGLAR1_RS05180	COG2207	Transcriptional regulator
CGLAR1_RS05195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGLAR1_RS05205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGLAR1_RS05215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CGLAR1_RS05220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGLAR1_RS05275	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CGLAR1_RS05280	COG1914	H( )-stimulated, divalent metal cation uptake system
CGLAR1_RS05285	COG2188	Transcriptional regulator
CGLAR1_RS05295	COG0114	fumarate hydratase activity
CGLAR1_RS05325	COG1960	acyl-CoA dehydrogenase activity
CGLAR1_RS05340	COG1494	fructose-1,6-bisphosphatase
CGLAR1_RS05355	COG2814	Major facilitator Superfamily
CGLAR1_RS05365	COG1570	exodeoxyribonuclease VII activity
CGLAR1_RS05380	COG0628	permease
CGLAR1_RS05390	COG0733	neurotransmitter:sodium symporter activity
CGLAR1_RS05400	COG0012	GTP binding
CGLAR1_RS05415	COG3609	addiction module antidote protein, CC2985 family
CGLAR1_RS05420	COG1733	regulation of RNA biosynthetic process
CGLAR1_RS05435	COG0494	nUDIX hydrolase
CGLAR1_RS05460	COG2814	Major facilitator Superfamily
CGLAR1_RS05475	COG0656	L-ascorbic acid biosynthetic process
CGLAR1_RS05480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGLAR1_RS05525	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CGLAR1_RS05530	COG0406	alpha-ribazole phosphatase activity
CGLAR1_RS05545	COG0488	(ABC) transporter
CGLAR1_RS05555	COG2824	Alkylphosphonate utilization operon protein PhnA
CGLAR1_RS05565	COG2814	Major facilitator Superfamily
CGLAR1_RS05570	COG1104	cysteine desulfurase activity
CGLAR1_RS05580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGLAR1_RS05595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CGLAR1_RS05600	COG2315	Protein conserved in bacteria
CGLAR1_RS05605	COG0095	Lipoate-protein ligase
CGLAR1_RS05615	COG2814	Major facilitator Superfamily
CGLAR1_RS05625	COG4721	ABC-type cobalt transport system, permease component
CGLAR1_RS05630	COG1122	ATPase activity
CGLAR1_RS05645	COG0387	Pfam Sodium calcium exchanger
CGLAR1_RS05660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGLAR1_RS05665	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CGLAR1_RS05675	COG2354	Protein conserved in bacteria
CGLAR1_RS05680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGLAR1_RS05700	COG5640	endopeptidase activity
CGLAR1_RS05710	COG3949	Membrane
CGLAR1_RS05725	COG1217	gtp-binding protein TYPA
CGLAR1_RS05730	COG0747	negative chemotaxis
CGLAR1_RS05765	COG2171	N-acyltransferase activity
CGLAR1_RS05770	COG1113	amino acid transport
CGLAR1_RS05780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGLAR1_RS05790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CGLAR1_RS05795	COG0463	Glycosyl transferase, family 2
CGLAR1_RS05820	COG0297	glycogen (starch) synthase activity
CGLAR1_RS05830	COG4122	O-methyltransferase activity
CGLAR1_RS05835	COG1595	DNA-templated transcription, initiation
CGLAR1_RS05880	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGLAR1_RS05880	COG0567	Dehydrogenase, E1 component
CGLAR1_RS05895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGLAR1_RS05900	COG2272	Belongs to the type-B carboxylesterase lipase family
CGLAR1_RS05920	COG2814	Major facilitator Superfamily
CGLAR1_RS05965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CGLAR1_RS05970	COG4988	ABC transporter
CGLAR1_RS05975	COG1294	oxidase, subunit
CGLAR1_RS05980	COG1271	oxidase subunit
CGLAR1_RS06020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGLAR1_RS06025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGLAR1_RS06045	COG0657	acetylesterase activity
CGLAR1_RS06050	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGLAR1_RS06080	COG2353	YceI-like domain
CGLAR1_RS06085	COG1846	Transcriptional regulator
CGLAR1_RS06100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGLAR1_RS06105	COG2217	Heavy metal translocating P-type atpase
CGLAR1_RS06115	COG2357	RelA SpoT domain protein
CGLAR1_RS06135	COG0019	diaminopimelate decarboxylase activity
CGLAR1_RS06160	COG0460	homoserine dehydrogenase
CGLAR1_RS06165	COG0083	homoserine kinase activity
CGLAR1_RS06185	COG1140	nitrate reductase beta subunit
CGLAR1_RS06200	COG0315	cyclic pyranopterin monophosphate synthase activity
CGLAR1_RS06200	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGLAR1_RS06210	COG1253	flavin adenine dinucleotide binding
CGLAR1_RS06220	COG0746	molybdenum cofactor guanylyltransferase activity
CGLAR1_RS06230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CGLAR1_RS06275	COG0356	it plays a direct role in the translocation of protons across the membrane
CGLAR1_RS06280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGLAR1_RS06285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGLAR1_RS06295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGLAR1_RS06300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGLAR1_RS06310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CGLAR1_RS06320	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CGLAR1_RS06330	COG0346	lactoylglutathione lyase activity
CGLAR1_RS06345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGLAR1_RS06350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGLAR1_RS06355	COG1116	anion transmembrane transporter activity
CGLAR1_RS06360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CGLAR1_RS06365	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CGLAR1_RS06370	COG0366	Alpha amylase catalytic
CGLAR1_RS06375	COG1119	ATPase activity
CGLAR1_RS06400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGLAR1_RS06405	COG1104	cysteine desulfurase activity
CGLAR1_RS06420	COG1396	sequence-specific DNA binding
CGLAR1_RS06480	COG0154	amidase activity
CGLAR1_RS06500	COG0205	6-phosphofructokinase activity
CGLAR1_RS06505	COG1609	Transcriptional regulator
CGLAR1_RS06510	COG1129	ABC transporter
CGLAR1_RS06515	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGLAR1_RS06520	COG1879	ABC-type sugar transport system periplasmic component
CGLAR1_RS06540	COG0385	Bile acid
CGLAR1_RS06555	COG0667	Aldo Keto reductase
CGLAR1_RS06560	COG1279	arginine transmembrane transporter activity
CGLAR1_RS06565	COG0583	DNA-binding transcription factor activity
CGLAR1_RS06570	COG0435	Glutathione S-transferase
CGLAR1_RS06585	COG0129	dihydroxy-acid dehydratase activity
CGLAR1_RS06595	COG0668	transmembrane transport
CGLAR1_RS06600	COG0028	Belongs to the TPP enzyme family
CGLAR1_RS06605	COG0440	acetolactate synthase activity
CGLAR1_RS06635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGLAR1_RS06665	COG0473	3-isopropylmalate dehydrogenase activity
CGLAR1_RS06685	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGLAR1_RS06705	COG3655	Transcriptional regulator
CGLAR1_RS06760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGLAR1_RS06770	COG0058	SHG alpha-glucan phosphorylase activity
CGLAR1_RS06780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGLAR1_RS06785	COG0730	response to heat
CGLAR1_RS06825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGLAR1_RS06835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGLAR1_RS06840	COG0066	3-isopropylmalate dehydratase activity
CGLAR1_RS06850	COG0406	alpha-ribazole phosphatase activity
CGLAR1_RS06850	COG0494	nUDIX hydrolase
CGLAR1_RS06875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CGLAR1_RS06880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGLAR1_RS06885	COG1461	Dihydroxyacetone kinase
CGLAR1_RS06890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CGLAR1_RS06900	COG0742	ribosomal rna small subunit methyltransferase
CGLAR1_RS06920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGLAR1_RS06955	COG2801	Transposase and inactivated derivatives
CGLAR1_RS06960	COG2963	transposase activity
CGLAR1_RS07050	COG0656	L-ascorbic acid biosynthetic process
CGLAR1_RS07065	COG0539	negative regulation of cytoplasmic translation
CGLAR1_RS07070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGLAR1_RS07070	COG1263	PTS System
CGLAR1_RS07070	COG2190	(PTS) system
CGLAR1_RS07075	COG0237	dephospho-CoA kinase activity
CGLAR1_RS07080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGLAR1_RS07100	COG0477	Major facilitator Superfamily
CGLAR1_RS07105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGLAR1_RS07110	COG1609	Transcriptional regulator
CGLAR1_RS07135	COG1733	regulation of RNA biosynthetic process
CGLAR1_RS07140	COG0702	epimerase
CGLAR1_RS07145	COG3973	AAA domain
CGLAR1_RS07170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGLAR1_RS07190	COG4209	transmembrane transport
CGLAR1_RS07205	COG3842	ATPase activity
CGLAR1_RS07215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGLAR1_RS07220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGLAR1_RS07225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGLAR1_RS07225	COG0072	phenylalanine-tRNA ligase activity
CGLAR1_RS07245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGLAR1_RS07260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGLAR1_RS07265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGLAR1_RS07275	COG0137	argininosuccinate synthase activity
CGLAR1_RS07280	COG0165	Argininosuccinate lyase
CGLAR1_RS07300	COG2835	tetraacyldisaccharide 4'-kinase activity
CGLAR1_RS07305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGLAR1_RS07335	COG0647	UMP catabolic process
CGLAR1_RS07350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGLAR1_RS07375	COG0494	nUDIX hydrolase
CGLAR1_RS07380	COG4974	Belongs to the 'phage' integrase family
CGLAR1_RS07385	COG0488	(ABC) transporter
CGLAR1_RS07405	COG2897	thiosulfate sulfurtransferase activity
CGLAR1_RS07410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CGLAR1_RS07420	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CGLAR1_RS07425	COG1160	GTP binding
CGLAR1_RS07445	COG1132	(ABC) transporter
CGLAR1_RS07450	COG1132	(ABC) transporter
CGLAR1_RS07455	COG0428	transporter
CGLAR1_RS07460	COG0025	NhaP-type Na H and K H
CGLAR1_RS07475	COG3012	SEC-C Motif Domain Protein
CGLAR1_RS07485	COG0653	protein targeting
CGLAR1_RS07490	COG1716	ATPase activity
CGLAR1_RS07525	COG1253	flavin adenine dinucleotide binding
CGLAR1_RS07530	COG1253	flavin adenine dinucleotide binding
CGLAR1_RS07535	COG0513	Belongs to the DEAD box helicase family
CGLAR1_RS07545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGLAR1_RS07565	COG0842	Transport permease protein
CGLAR1_RS07575	COG3639	organic phosphonate transmembrane transporter activity
CGLAR1_RS07580	COG3639	organic phosphonate transmembrane transporter activity
CGLAR1_RS07585	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CGLAR1_RS07600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CGLAR1_RS07600	COG0352	thiamine-phosphate diphosphorylase activity
CGLAR1_RS07600	COG0351	phosphomethylpyrimidine kinase
CGLAR1_RS07605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CGLAR1_RS07610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGLAR1_RS07620	COG0477	Major facilitator Superfamily
CGLAR1_RS07625	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CGLAR1_RS07650	COG0659	secondary active sulfate transmembrane transporter activity
CGLAR1_RS07680	COG0463	Glycosyl transferase, family 2
CGLAR1_RS07735	COG0805	protein transport
CGLAR1_RS07740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGLAR1_RS07765	COG4122	O-methyltransferase activity
CGLAR1_RS07780	COG1362	aminopeptidase activity
CGLAR1_RS07795	COG2814	Major facilitator Superfamily
CGLAR1_RS07800	COG1027	Aspartate ammonia-lyase
CGLAR1_RS07815	COG0546	phosphoglycolate phosphatase activity
CGLAR1_RS07820	COG0646	methionine synthase
CGLAR1_RS07820	COG1410	methionine synthase
CGLAR1_RS07830	COG2072	flavoprotein involved in K transport
CGLAR1_RS07835	COG0798	PFAM Bile acid sodium symporter
CGLAR1_RS07840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGLAR1_RS07845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGLAR1_RS07860	COG1968	undecaprenyl-diphosphatase activity
CGLAR1_RS07865	COG0667	Aldo Keto reductase
CGLAR1_RS07890	COG1881	PFAM PEBP family protein
CGLAR1_RS07895	COG1132	(ABC) transporter
CGLAR1_RS07900	COG1132	(ABC) transporter
CGLAR1_RS07965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CGLAR1_RS07970	COG0791	NLP P60 protein
CGLAR1_RS07970	COG3883	PFAM NLP P60 protein
CGLAR1_RS07980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGLAR1_RS07985	COG1309	transcriptional regulator
CGLAR1_RS08005	COG3830	Belongs to the UPF0237 family
CGLAR1_RS08010	COG2848	UPF0210 protein
CGLAR1_RS08015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CGLAR1_RS08035	COG0488	(ABC) transporter
CGLAR1_RS08060	COG0822	iron-sulfur transferase activity
CGLAR1_RS08070	COG0396	ATPase activity
CGLAR1_RS08125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CGLAR1_RS08130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGLAR1_RS08155	COG2423	ornithine cyclodeaminase activity
CGLAR1_RS08160	COG0004	ammonium transporteR
CGLAR1_RS08165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGLAR1_RS08170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CGLAR1_RS08175	COG0149	triose-phosphate isomerase activity
CGLAR1_RS08180	COG0126	phosphoglycerate kinase activity
CGLAR1_RS08185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGLAR1_RS08190	COG1481	regulation of sporulation
CGLAR1_RS08205	COG0322	excinuclease ABC activity
CGLAR1_RS08250	COG0242	peptide deformylase activity
CGLAR1_RS08260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGLAR1_RS08270	COG1758	RNA polymerase activity
CGLAR1_RS08275	COG0194	GDP metabolic process
CGLAR1_RS08290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGLAR1_RS08295	COG0505	Belongs to the CarA family
CGLAR1_RS08300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGLAR1_RS08305	COG0540	Belongs to the ATCase OTCase family
CGLAR1_RS08310	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGLAR1_RS08335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGLAR1_RS08345	COG0006	proline dipeptidase activity
CGLAR1_RS08350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGLAR1_RS08355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGLAR1_RS08360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGLAR1_RS08375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS08385	COG1120	ATPase activity
CGLAR1_RS08390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGLAR1_RS08395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGLAR1_RS08400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGLAR1_RS08430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGLAR1_RS08455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGLAR1_RS08465	COG1760	l-serine dehydratase
CGLAR1_RS08470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGLAR1_RS08475	COG0124	histidyl-tRNA synthetase
CGLAR1_RS08485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CGLAR1_RS08500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGLAR1_RS08505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGLAR1_RS08515	COG2826	transposase and inactivated derivatives, IS30 family
CGLAR1_RS08520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGLAR1_RS08525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGLAR1_RS08540	COG0632	four-way junction helicase activity
CGLAR1_RS08545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CGLAR1_RS08550	COG0217	transcriptional regulatory protein
CGLAR1_RS08555	COG1946	Acyl-CoA thioesterase
CGLAR1_RS08570	COG0438	transferase activity, transferring glycosyl groups
CGLAR1_RS08575	COG1560	Kdo2-lipid A biosynthetic process
CGLAR1_RS08580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGLAR1_RS08590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGLAR1_RS08595	COG2837	iron assimilation
CGLAR1_RS08600	COG2847	Copper chaperone PCu(A)C
CGLAR1_RS08635	COG1929	Belongs to the glycerate kinase type-1 family
CGLAR1_RS08655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGLAR1_RS08660	COG3253	May function as heme-dependent peroxidase
CGLAR1_RS08670	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CGLAR1_RS08680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGLAR1_RS08690	COG0756	dUTP diphosphatase activity
CGLAR1_RS08710	COG0483	inositol monophosphate 1-phosphatase activity
CGLAR1_RS08725	COG2311	Membrane
CGLAR1_RS08735	COG1061	Type III restriction enzyme res subunit
CGLAR1_RS08765	COG1321	iron dependent repressor
CGLAR1_RS08770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGLAR1_RS08790	COG0583	DNA-binding transcription factor activity
CGLAR1_RS08800	COG1643	Atp-dependent helicase
CGLAR1_RS08820	COG1349	DNA-binding transcription factor activity
CGLAR1_RS08830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGLAR1_RS08840	COG1105	Belongs to the carbohydrate kinase PfkB family
CGLAR1_RS08845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGLAR1_RS08845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGLAR1_RS08845	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CGLAR1_RS08860	COG2233	PERMEase
CGLAR1_RS08865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGLAR1_RS08880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGLAR1_RS08885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGLAR1_RS08895	COG1196	nuclear chromosome segregation
CGLAR1_RS08915	COG1126	abc transporter atp-binding protein
CGLAR1_RS08920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGLAR1_RS08925	COG0765	amino acid transport
CGLAR1_RS08930	COG0765	amino acid transport
CGLAR1_RS08935	COG2137	regulation of response to DNA damage stimulus
CGLAR1_RS08955	COG1268	BioY protein
CGLAR1_RS08960	COG1122	ATPase activity
CGLAR1_RS08970	COG1842	Phage shock protein A
CGLAR1_RS08975	COG1396	sequence-specific DNA binding
CGLAR1_RS09000	COG1674	ftsk spoiiie
CGLAR1_RS09010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGLAR1_RS09015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGLAR1_RS09020	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CGLAR1_RS09035	COG1185	polyribonucleotide nucleotidyltransferase activity
CGLAR1_RS09065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CGLAR1_RS09075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CGLAR1_RS09080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGLAR1_RS09085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGLAR1_RS09100	COG0779	Required for maturation of 30S ribosomal subunits
CGLAR1_RS09110	COG4166	transmembrane transport
CGLAR1_RS09115	COG0601	transmembrane transport
CGLAR1_RS09120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGLAR1_RS09125	COG4172	Belongs to the ABC transporter superfamily
CGLAR1_RS09130	COG0442	prolyl-tRNA aminoacylation
CGLAR1_RS09135	COG3022	response to hydroperoxide
CGLAR1_RS09155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CGLAR1_RS09205	COG2197	response regulator
CGLAR1_RS09210	COG3850	Histidine kinase
CGLAR1_RS09215	COG0577	efflux transmembrane transporter activity
CGLAR1_RS09220	COG0577	efflux transmembrane transporter activity
CGLAR1_RS09220	COG1136	(ABC) transporter
CGLAR1_RS09225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGLAR1_RS09230	COG0750	zinc metalloprotease
CGLAR1_RS09250	COG1131	(ABC) transporter
CGLAR1_RS09255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CGLAR1_RS09270	COG0233	cytoplasmic translational termination
CGLAR1_RS09280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGLAR1_RS09285	COG0052	Belongs to the universal ribosomal protein uS2 family
CGLAR1_RS09295	COG4974	Belongs to the 'phage' integrase family
CGLAR1_RS09305	COG0606	chelatase, subunit chli
CGLAR1_RS09310	COG0792	nuclease activity
CGLAR1_RS09320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGLAR1_RS09325	COG0681	Belongs to the peptidase S26 family
CGLAR1_RS09335	COG0335	large ribosomal subunit rRNA binding
CGLAR1_RS09340	COG0352	thiamine-phosphate diphosphorylase activity
CGLAR1_RS09345	COG2022	thiamine diphosphate biosynthetic process
CGLAR1_RS09345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGLAR1_RS09360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CGLAR1_RS09370	COG1609	Transcriptional regulator
CGLAR1_RS09375	COG0471	metal ion transport
CGLAR1_RS09380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGLAR1_RS09395	COG0336	Belongs to the RNA methyltransferase TrmD family
CGLAR1_RS09405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGLAR1_RS09440	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CGLAR1_RS09470	COG1254	Belongs to the acylphosphatase family
CGLAR1_RS09500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGLAR1_RS09505	COG0571	ribonuclease III activity
CGLAR1_RS09520	COG1132	(ABC) transporter
CGLAR1_RS09525	COG1132	(ABC) transporter
CGLAR1_RS09530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGLAR1_RS09535	COG1929	Belongs to the glycerate kinase type-1 family
CGLAR1_RS09565	COG0058	SHG alpha-glucan phosphorylase activity
CGLAR1_RS09570	COG2514	catechol 2,3-dioxygenase activity
CGLAR1_RS09575	COG0469	pyruvate kinase activity
CGLAR1_RS09585	COG0134	indole-3-glycerol-phosphate synthase activity
CGLAR1_RS09595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CGLAR1_RS09605	COG0483	inositol monophosphate 1-phosphatase activity
CGLAR1_RS09610	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGLAR1_RS09675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGLAR1_RS09695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGLAR1_RS09700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGLAR1_RS09730	COG2264	protein methyltransferase activity
CGLAR1_RS09740	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS09745	COG1609	Transcriptional regulator
CGLAR1_RS09750	COG1120	ATPase activity
CGLAR1_RS09755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGLAR1_RS09815	COG1739	Uncharacterized protein family UPF0029
CGLAR1_RS09825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGLAR1_RS09860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGLAR1_RS09870	COG0488	(ABC) transporter
CGLAR1_RS09880	COG0252	asparaginase activity
CGLAR1_RS09910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGLAR1_RS09920	COG3599	regulation of cell shape
CGLAR1_RS09930	COG1799	cell septum assembly
CGLAR1_RS09935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGLAR1_RS09940	COG1496	oxidoreductase activity
CGLAR1_RS09945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGLAR1_RS09950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CGLAR1_RS09960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGLAR1_RS09970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGLAR1_RS09985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGLAR1_RS09990	COG0768	penicillin binding
CGLAR1_RS10000	COG0275	rRNA processing
CGLAR1_RS10020	COG0456	acetyltransferase
CGLAR1_RS10030	COG0142	geranyltranstransferase activity
CGLAR1_RS10045	COG0515	serine threonine protein kinase
CGLAR1_RS10045	COG2815	serine threonine protein kinase
CGLAR1_RS10060	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CGLAR1_RS10075	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGLAR1_RS10075	COG5479	isomerase activity
CGLAR1_RS10095	COG1940	carbohydrate kinase activity
CGLAR1_RS10100	COG0438	transferase activity, transferring glycosyl groups
CGLAR1_RS10110	COG0791	NLP P60 protein
CGLAR1_RS10115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CGLAR1_RS10120	COG0723	plastoquinol--plastocyanin reductase activity
CGLAR1_RS10125	COG2010	Cytochrome c
CGLAR1_RS10130	COG1845	cytochrome c oxidase, subunit III
CGLAR1_RS10145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CGLAR1_RS10170	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CGLAR1_RS10175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CGLAR1_RS10185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGLAR1_RS10190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGLAR1_RS10200	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGLAR1_RS10205	COG3547	Transposase (IS116 IS110 IS902 family)
CGLAR1_RS10225	COG2985	domain, Protein
CGLAR1_RS10225	COG0569	domain protein
CGLAR1_RS10235	COG0174	glutamine synthetase
CGLAR1_RS10255	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CGLAR1_RS10290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGLAR1_RS10300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGLAR1_RS10330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CGLAR1_RS10335	COG0174	glutamine synthetase
CGLAR1_RS10360	COG0557	exoribonuclease II activity
CGLAR1_RS10380	COG3323	Protein of unknown function (DUF1653)
CGLAR1_RS10380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGLAR1_RS10415	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGLAR1_RS10445	COG0596	Alpha beta hydrolase
CGLAR1_RS10450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGLAR1_RS10540	COG3387	PFAM Glycoside hydrolase 15-related
CGLAR1_RS10550	COG0358	DNA primase activity
CGLAR1_RS10565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGLAR1_RS10575	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CGLAR1_RS10600	COG0423	glycine-tRNA ligase activity
CGLAR1_RS10625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGLAR1_RS10635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGLAR1_RS10660	COG0484	heat shock protein binding
CGLAR1_RS10700	COG1132	(ABC) transporter
CGLAR1_RS10725	COG0366	Alpha amylase catalytic
CGLAR1_RS10735	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGLAR1_RS10760	COG1114	Component of the transport system for branched-chain amino acids
CGLAR1_RS10765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGLAR1_RS10770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGLAR1_RS10785	COG0247	lactate metabolic process
CGLAR1_RS10785	COG0277	FAD linked oxidase domain protein
CGLAR1_RS10810	COG0747	negative chemotaxis
CGLAR1_RS10815	COG0601	transmembrane transport
CGLAR1_RS10820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGLAR1_RS10835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGLAR1_RS10845	COG0385	Bile acid
CGLAR1_RS10850	COG0676	glucose-6-phosphate 1-epimerase activity
CGLAR1_RS10855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CGLAR1_RS10860	COG2224	Isocitrate lyase
CGLAR1_RS10875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGLAR1_RS10915	COG0481	GTPase activity
CGLAR1_RS10930	COG1280	lysine exporter protein (LysE YggA)
CGLAR1_RS10955	COG1307	EDD domain protein, DegV family
CGLAR1_RS10960	COG0406	alpha-ribazole phosphatase activity
CGLAR1_RS10970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGLAR1_RS10985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGLAR1_RS10990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGLAR1_RS10995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGLAR1_RS11030	COG1530	ribonuclease E activity
CGLAR1_RS11075	COG0285	dihydrofolate synthase activity
CGLAR1_RS11080	COG0525	valine-tRNA ligase activity
CGLAR1_RS11090	COG0443	Heat shock 70 kDa protein
CGLAR1_RS11100	COG0039	L-malate dehydrogenase activity
CGLAR1_RS11105	COG1309	transcriptional regulator
CGLAR1_RS11125	COG2814	Major facilitator Superfamily
CGLAR1_RS11135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGLAR1_RS11155	COG1414	Transcriptional regulator
CGLAR1_RS11160	COG0183	Belongs to the thiolase family
CGLAR1_RS11165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGLAR1_RS11180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGLAR1_RS11185	COG3485	protocatechuate 3,4-dioxygenase
CGLAR1_RS11190	COG3485	protocatechuate 3,4-dioxygenase
CGLAR1_RS11200	COG4829	muconolactone delta-isomerase
CGLAR1_RS11205	COG4948	Mandelate Racemase Muconate Lactonizing
CGLAR1_RS11210	COG3485	protocatechuate 3,4-dioxygenase
CGLAR1_RS11215	COG4638	Rieske (2fe-2S)
CGLAR1_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
CGLAR1_RS11240	COG2814	Major facilitator Superfamily
CGLAR1_RS11250	COG0740	serine-type endopeptidase activity
CGLAR1_RS11255	COG0740	serine-type endopeptidase activity
CGLAR1_RS11320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGLAR1_RS11370	COG4172	Belongs to the ABC transporter superfamily
CGLAR1_RS11375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGLAR1_RS11380	COG0601	transmembrane transport
CGLAR1_RS11385	COG0747	negative chemotaxis
CGLAR1_RS11395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGLAR1_RS11410	COG4221	oxidoreductase activity
CGLAR1_RS11425	COG1119	ATPase activity
CGLAR1_RS11480	COG1785	Belongs to the alkaline phosphatase family
CGLAR1_RS11520	COG3842	ATPase activity
CGLAR1_RS11525	COG0463	Glycosyl transferase, family 2
CGLAR1_RS11550	COG1691	(AIR) carboxylase
CGLAR1_RS11560	COG2963	transposase activity
CGLAR1_RS11565	COG2801	Transposase and inactivated derivatives
CGLAR1_RS11570	COG3622	Belongs to the hyi family
CGLAR1_RS11575	COG4221	oxidoreductase activity
CGLAR1_RS11580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CGLAR1_RS11590	COG1376	ErfK ybiS ycfS ynhG family protein
CGLAR1_RS11630	COG2066	Belongs to the glutaminase family
CGLAR1_RS11645	COG1904	glucuronate isomerase
CGLAR1_RS11645	COG1102	Psort location Cytoplasmic, score
CGLAR1_RS11650	COG3265	gluconokinase activity
CGLAR1_RS11660	COG1335	isochorismatase
CGLAR1_RS11680	COG0736	holo-[acyl-carrier-protein] synthase activity
CGLAR1_RS11685	COG2814	Major facilitator Superfamily
CGLAR1_RS11700	COG2030	dehydratase
CGLAR1_RS11715	COG3835	regulator
CGLAR1_RS11740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGLAR1_RS11745	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CGLAR1_RS11755	COG1234	tRNA 3'-trailer cleavage
CGLAR1_RS11760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CGLAR1_RS11780	COG3191	aminopeptidase activity
CGLAR1_RS11800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CGLAR1_RS11825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGLAR1_RS11840	COG2186	Transcriptional regulator
CGLAR1_RS11855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGLAR1_RS11875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CGLAR1_RS11890	COG0604	alcohol dehydrogenase
CGLAR1_RS11905	COG0033	Phosphoglucomutase
CGLAR1_RS11910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGLAR1_RS11915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGLAR1_RS11940	COG1136	(ABC) transporter
CGLAR1_RS11995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGLAR1_RS12005	COG2197	response regulator
CGLAR1_RS12015	COG1045	serine acetyltransferase
CGLAR1_RS12040	COG0045	succinate-CoA ligase (ADP-forming) activity
CGLAR1_RS12055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGLAR1_RS12085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGLAR1_RS12105	COG0456	acetyltransferase
CGLAR1_RS12115	COG1597	lipid kinase activity
CGLAR1_RS12130	COG0354	folic acid binding
CGLAR1_RS12140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CGLAR1_RS12170	COG0047	phosphoribosylformylglycinamidine synthase activity
CGLAR1_RS12175	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGLAR1_RS12180	COG0386	Belongs to the glutathione peroxidase family
CGLAR1_RS12200	COG1301	dicarboxylic acid transport
CGLAR1_RS12210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CGLAR1_RS12220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGLAR1_RS12225	COG0436	Aminotransferase
CGLAR1_RS12230	COG0151	Belongs to the GarS family
CGLAR1_RS12240	COG1484	DNA-dependent DNA replication
CGLAR1_RS12250	COG2226	methyltransferase
CGLAR1_RS12250	COG2267	carboxylic ester hydrolase activity
CGLAR1_RS12255	COG3104	oligopeptide transport
CGLAR1_RS12260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGLAR1_RS12265	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CGLAR1_RS12270	COG2205	protein histidine kinase activity
CGLAR1_RS12275	COG0745	RESPONSE REGULATOR receiver
CGLAR1_RS12290	COG0028	Belongs to the TPP enzyme family
CGLAR1_RS12300	COG1309	transcriptional regulator
CGLAR1_RS12315	COG1053	succinate dehydrogenase
CGLAR1_RS12320	COG1053	succinate dehydrogenase
CGLAR1_RS12335	COG0477	Major facilitator Superfamily
CGLAR1_RS12340	COG0583	DNA-binding transcription factor activity
CGLAR1_RS12350	COG1748	Saccharopine dehydrogenase
CGLAR1_RS12375	COG0582	viral genome integration into host DNA
CGLAR1_RS12450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CGLAR1_RS12465	COG1609	Transcriptional regulator
CGLAR1_RS12475	COG1121	(ABC) transporter
CGLAR1_RS12480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGLAR1_RS12490	COG1053	succinate dehydrogenase
CGLAR1_RS12500	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS12505	COG0477	Major facilitator Superfamily
CGLAR1_RS12520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGLAR1_RS12525	COG0215	cysteine-tRNA ligase activity
CGLAR1_RS12535	COG1621	beta-fructofuranosidase activity
CGLAR1_RS12545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGLAR1_RS12550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGLAR1_RS12575	COG4166	transmembrane transport
CGLAR1_RS12580	COG0601	transmembrane transport
CGLAR1_RS12585	COG0444	Belongs to the ABC transporter superfamily
CGLAR1_RS12590	COG4608	Belongs to the ABC transporter superfamily
CGLAR1_RS12595	COG1280	lysine exporter protein (LysE YggA)
CGLAR1_RS12600	COG1522	sequence-specific DNA binding
CGLAR1_RS12610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CGLAR1_RS12615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CGLAR1_RS12630	COG2205	protein histidine kinase activity
CGLAR1_RS12635	COG2847	Copper chaperone PCu(A)C
CGLAR1_RS12640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CGLAR1_RS12690	COG0542	response to heat
CGLAR1_RS12705	COG2207	Transcriptional regulator
CGLAR1_RS12720	COG2814	Major facilitator Superfamily
CGLAR1_RS12730	COG2826	transposase and inactivated derivatives, IS30 family
CGLAR1_RS12735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CGLAR1_RS12740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGLAR1_RS12760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CGLAR1_RS12775	COG0302	gtp cyclohydrolase
CGLAR1_RS12780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGLAR1_RS12790	COG0037	tRNA processing
CGLAR1_RS12795	COG2027	D-alanyl-D-alanine carboxypeptidase
CGLAR1_RS12800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CGLAR1_RS12805	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGLAR1_RS12810	COG3766	membrane
CGLAR1_RS12830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGLAR1_RS12830	COG2190	(PTS) system
CGLAR1_RS12830	COG1263	PTS System
CGLAR1_RS12845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGLAR1_RS12860	COG1012	belongs to the aldehyde dehydrogenase family
CGLAR1_RS12865	COG2326	polyphosphate kinase activity
CGLAR1_RS12875	COG0459	protein refolding
CGLAR1_RS12885	COG1100	Small GTP-binding protein
CGLAR1_RS12935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGLAR1_RS12935	COG2111	Na H antiporter
CGLAR1_RS12940	COG1006	Multisubunit Na H antiporter MnhC subunit
CGLAR1_RS12945	COG0651	ATP synthesis coupled electron transport
CGLAR1_RS12955	COG2212	antiporter activity
CGLAR1_RS12960	COG1320	monovalent cation:proton antiporter activity
CGLAR1_RS12985	COG0242	peptide deformylase activity
CGLAR1_RS13000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGLAR1_RS13005	COG2814	Major facilitator Superfamily
CGLAR1_RS13025	COG1131	(ABC) transporter
CGLAR1_RS13045	COG0515	serine threonine protein kinase
CGLAR1_RS13050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGLAR1_RS13055	COG0280	phosphate acetyltransferase
CGLAR1_RS13100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGLAR1_RS13105	COG4129	membrane
CGLAR1_RS13110	COG0191	fructose-bisphosphate aldolase activity
CGLAR1_RS13125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGLAR1_RS13135	COG2897	thiosulfate sulfurtransferase activity
CGLAR1_RS13155	COG0542	response to heat
CGLAR1_RS13165	COG0640	Transcriptional regulator
CGLAR1_RS13235	COG1012	belongs to the aldehyde dehydrogenase family
CGLAR1_RS13240	COG0789	Transcriptional regulator
CGLAR1_RS13245	COG0484	heat shock protein binding
CGLAR1_RS13250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGLAR1_RS13255	COG0443	Heat shock 70 kDa protein
CGLAR1_RS13295	COG0730	response to heat
CGLAR1_RS13320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGLAR1_RS13365	COG3845	ABC transporter
CGLAR1_RS13375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGLAR1_RS13385	COG1122	ATPase activity
CGLAR1_RS13460	COG2818	Glycosylase
CGLAR1_RS13465	COG1017	nitric oxide dioxygenase activity
CGLAR1_RS13465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGLAR1_RS13475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CGLAR1_RS13480	COG3711	transcriptional antiterminator
CGLAR1_RS13510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGLAR1_RS13535	COG1472	Belongs to the glycosyl hydrolase 3 family
CGLAR1_RS13550	COG4981	capsule polysaccharide biosynthetic process
CGLAR1_RS13575	COG0438	transferase activity, transferring glycosyl groups
CGLAR1_RS13585	COG0500	methyltransferase
CGLAR1_RS13590	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CGLAR1_RS13625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGLAR1_RS13630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGLAR1_RS13630	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CGLAR1_RS13630	COG3321	synthase
CGLAR1_RS13635	COG0318	PFAM AMP-dependent synthetase and ligase
CGLAR1_RS13640	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CGLAR1_RS13650	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGLAR1_RS13650	COG5479	isomerase activity
CGLAR1_RS13665	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CGLAR1_RS13670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CGLAR1_RS13675	COG0671	phosphoesterase, PA-phosphatase related
CGLAR1_RS13680	COG1216	Glycosyl transferase, family 2
CGLAR1_RS13690	COG0671	phosphoesterase, PA-phosphatase related
CGLAR1_RS13720	COG0561	phosphatase activity
CGLAR1_RS13730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGLAR1_RS13735	COG2188	Transcriptional regulator
CGLAR1_RS13760	COG0077	Prephenate dehydratase
CGLAR1_RS13780	COG1316	TRANSCRIPTIONal
CGLAR1_RS13810	COG2610	gluconate transmembrane transporter activity
CGLAR1_RS13815	COG0469	pyruvate kinase activity
CGLAR1_RS13820	COG0039	L-malate dehydrogenase activity
CGLAR1_RS13840	COG2188	Transcriptional regulator
CGLAR1_RS13845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CGLAR1_RS13850	COG0477	Major facilitator Superfamily
CGLAR1_RS13905	COG0583	DNA-binding transcription factor activity
CGLAR1_RS13910	COG2814	Major facilitator Superfamily
CGLAR1_RS13940	COG2197	response regulator
CGLAR1_RS13960	COG3764	Sortase (surface protein transpeptidase)
CGLAR1_RS13965	COG0706	membrane insertase activity
CGLAR1_RS13985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGLAR1_RS13995	COG0564	pseudouridine synthase activity
CGLAR1_RS14025	COG1842	Phage shock protein A
CGLAR1_RS14080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGLAR1_RS14090	COG0477	Major facilitator Superfamily
CGLAR1_RS14095	COG1695	Transcriptional regulator
CGLAR1_RS14105	COG0305	Participates in initiation and elongation during chromosome replication
CGLAR1_RS14115	COG0629	single-stranded DNA binding
CGLAR1_RS14120	COG0360	Binds together with S18 to 16S ribosomal RNA
CGLAR1_RS14135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGLAR1_RS14145	COG1846	Transcriptional regulator
CGLAR1_RS14165	COG1054	Belongs to the UPF0176 family
CGLAR1_RS14175	COG1136	(ABC) transporter
CGLAR1_RS14185	COG1260	myo-inositol-1-phosphate synthase
CGLAR1_RS14195	COG4868	Belongs to the UPF0371 family
CGLAR1_RS14205	COG0783	Belongs to the Dps family
CGLAR1_RS14210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGLAR1_RS14215	COG1690	Belongs to the RtcB family
CGLAR1_RS14225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGLAR1_RS14260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGLAR1_RS14265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGLAR1_RS14285	COG0778	Nitroreductase
CGLAR1_RS14300	COG2832	Protein of unknown function (DUF454)
CGLAR1_RS14315	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGLAR1_RS14330	COG2814	Major facilitator Superfamily
CGLAR1_RS14335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGLAR1_RS14365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGLAR1_RS14370	COG0512	Glutamine amidotransferase of anthranilate synthase
CGLAR1_RS14380	COG0135	phosphoribosylanthranilate isomerase activity
CGLAR1_RS14380	COG0134	indole-3-glycerol-phosphate synthase activity
CGLAR1_RS14385	COG0133	tryptophan synthase activity
CGLAR1_RS14390	COG0159	tryptophan synthase activity
CGLAR1_RS14400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGLAR1_RS14405	COG1131	(ABC) transporter
CGLAR1_RS14435	COG0640	Transcriptional regulator
CGLAR1_RS14440	COG1902	pentaerythritol trinitrate reductase activity
CGLAR1_RS14445	COG0702	epimerase
CGLAR1_RS14475	COG3104	oligopeptide transport
CGLAR1_RS14480	COG1309	transcriptional regulator
CGLAR1_RS14490	COG1454	alcohol dehydrogenase
CGLAR1_RS14495	COG2814	Major facilitator Superfamily
CGLAR1_RS14500	COG1414	Transcriptional regulator
CGLAR1_RS14505	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS14515	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS14520	COG0673	inositol 2-dehydrogenase activity
CGLAR1_RS14525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CGLAR1_RS14535	COG0477	Major facilitator Superfamily
CGLAR1_RS14560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGLAR1_RS14580	COG0351	phosphomethylpyrimidine kinase
CGLAR1_RS14595	COG1687	branched-chain amino acid
CGLAR1_RS14600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CGLAR1_RS14605	COG1678	Uncharacterized ACR, COG1678
CGLAR1_RS14610	COG0617	tRNA 3'-terminal CCA addition
CGLAR1_RS14630	COG1595	DNA-templated transcription, initiation
CGLAR1_RS14640	COG3118	belongs to the thioredoxin family
CGLAR1_RS14645	COG3409	Peptidoglycan-binding domain 1 protein
CGLAR1_RS14645	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGLAR1_RS14660	COG1192	Involved in chromosome partitioning
CGLAR1_RS14675	COG0594	ribonuclease P activity
CGLAR1_RS14865	COG1263	PTS System
CGLAR1_RS14865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGLAR1_RS14865	COG2190	(PTS) system