locus-tag	class	description
SB89_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SB89_RS00010	COG0592	DNA-directed DNA polymerase activity
SB89_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SB89_RS00025	COG0187	DNA topoisomerase II activity
SB89_RS00080	COG2855	membrane
SB89_RS00085	COG0583	DNA-binding transcription factor activity
SB89_RS00100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SB89_RS00100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SB89_RS00120	COG0737	Belongs to the 5'-nucleotidase family
SB89_RS00150	COG0803	Belongs to the bacterial solute-binding protein 9 family
SB89_RS00155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SB89_RS00160	COG1120	ATPase activity
SB89_RS00170	COG1172	Belongs to the binding-protein-dependent transport system permease family
SB89_RS00175	COG1129	ABC transporter
SB89_RS00205	COG1120	ATPase activity
SB89_RS00220	COG0515	serine threonine protein kinase
SB89_RS00220	COG2815	serine threonine protein kinase
SB89_RS00225	COG0515	serine threonine protein kinase
SB89_RS00230	COG0768	penicillin binding
SB89_RS00250	COG1716	ATPase activity
SB89_RS00310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SB89_RS00315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SB89_RS00320	COG1937	Protein conserved in bacteria
SB89_RS00365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SB89_RS00375	COG2851	Citrate transporter
SB89_RS00380	COG3290	protein histidine kinase activity
SB89_RS00385	COG4565	transcriptional regulatory protein
SB89_RS00390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SB89_RS00400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SB89_RS00435	COG0402	S-adenosylhomocysteine deaminase activity
SB89_RS00445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SB89_RS00475	COG0832	Belongs to the urease beta subunit family
SB89_RS00480	COG0804	urea catabolic process
SB89_RS00490	COG0830	nickel cation binding
SB89_RS00510	COG2814	Major facilitator Superfamily
SB89_RS00520	COG0326	Molecular chaperone. Has ATPase activity
SB89_RS00525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SB89_RS00555	COG1012	belongs to the aldehyde dehydrogenase family
SB89_RS00560	COG0667	Aldo Keto reductase
SB89_RS00565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SB89_RS00575	COG2149	membrane
SB89_RS00585	COG1396	sequence-specific DNA binding
SB89_RS00595	COG0346	lactoylglutathione lyase activity
SB89_RS00610	COG2814	Major facilitator Superfamily
SB89_RS00620	COG1070	Carbohydrate kinase
SB89_RS00625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SB89_RS00635	COG3177	Filamentation induced by cAMP protein fic
SB89_RS00660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SB89_RS00695	COG2860	membrane
SB89_RS00715	COG3180	Ammonia monooxygenase
SB89_RS00725	COG0730	response to heat
SB89_RS00735	COG1643	Atp-dependent helicase
SB89_RS00740	COG0110	maltose O-acetyltransferase activity
SB89_RS00750	COG2818	Glycosylase
SB89_RS00755	COG1280	lysine exporter protein (LysE YggA)
SB89_RS00785	COG0251	oxidation-reduction process
SB89_RS00795	COG3590	peptidase
SB89_RS00810	COG2188	Transcriptional regulator
SB89_RS00815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SB89_RS00830	COG3718	enzyme involved in inositol metabolism
SB89_RS00835	COG3962	Belongs to the TPP enzyme family
SB89_RS00850	COG1082	Xylose isomerase domain protein TIM barrel
SB89_RS00875	COG1609	Transcriptional regulator
SB89_RS00885	COG1609	Transcriptional regulator
SB89_RS00890	COG0673	inositol 2-dehydrogenase activity
SB89_RS00900	COG1278	Cold shock
SB89_RS00915	COG3842	ATPase activity
SB89_RS00940	COG1609	Transcriptional regulator
SB89_RS00950	COG2814	Major facilitator Superfamily
SB89_RS00960	COG0069	glutamate synthase activity
SB89_RS00960	COG0070	glutamate synthase
SB89_RS00960	COG0067	glutamate synthase
SB89_RS00975	COG2197	response regulator
SB89_RS00995	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS01000	COG1396	sequence-specific DNA binding
SB89_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS01020	COG0277	FAD linked oxidase domain protein
SB89_RS01055	COG2258	MOSC domain
SB89_RS01060	COG1216	Glycosyl transferase, family 2
SB89_RS01105	COG1115	amino acid carrier protein
SB89_RS01130	COG0521	Mo-molybdopterin cofactor biosynthetic process
SB89_RS01130	COG0315	cyclic pyranopterin monophosphate synthase activity
SB89_RS01150	COG0725	ABC transporter, periplasmic molybdate-binding protein
SB89_RS01160	COG3842	ATPase activity
SB89_RS01165	COG1950	PFAM Membrane protein of
SB89_RS01170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SB89_RS01185	COG2239	Acts as a magnesium transporter
SB89_RS01190	COG0471	metal ion transport
SB89_RS01200	COG0287	Prephenate dehydrogenase
SB89_RS01215	COG3237	CsbD-like
SB89_RS01230	COG2409	Drug exporters of the RND superfamily
SB89_RS01235	COG0343	queuine tRNA-ribosyltransferase activity
SB89_RS01265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SB89_RS01290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SB89_RS01310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SB89_RS01330	COG3442	glutamine amidotransferase
SB89_RS01335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SB89_RS01360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SB89_RS01365	COG0697	spore germination
SB89_RS01370	COG0527	aspartate kinase activity
SB89_RS01375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SB89_RS01410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SB89_RS01430	COG0798	PFAM Bile acid sodium symporter
SB89_RS01435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SB89_RS01455	COG0651	ATP synthesis coupled electron transport
SB89_RS01460	COG1006	Multisubunit Na H antiporter MnhC subunit
SB89_RS01465	COG2111	Na H antiporter
SB89_RS01465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SB89_RS01480	COG0745	RESPONSE REGULATOR receiver
SB89_RS01485	COG5002	protein histidine kinase activity
SB89_RS01485	COG3850	Histidine kinase
SB89_RS01515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SB89_RS01540	COG0477	Major facilitator Superfamily
SB89_RS01550	COG1846	Transcriptional regulator
SB89_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS01565	COG1960	acyl-CoA dehydrogenase activity
SB89_RS01575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SB89_RS01580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SB89_RS01595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SB89_RS01660	COG1205	dead DEAH box helicase
SB89_RS01660	COG1111	helicase
SB89_RS01665	COG1278	Cold shock
SB89_RS01670	COG1754	DNA topoisomerase type I activity
SB89_RS01670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SB89_RS01740	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS01745	COG2814	Major facilitator Superfamily
SB89_RS01775	COG0737	Belongs to the 5'-nucleotidase family
SB89_RS01800	COG1518	maintenance of DNA repeat elements
SB89_RS01840	COG1064	alcohol dehydrogenase
SB89_RS01855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SB89_RS01865	COG1088	dTDP-glucose 4,6-dehydratase activity
SB89_RS01870	COG0778	Nitroreductase
SB89_RS01875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SB89_RS01895	COG1505	serine-type exopeptidase activity
SB89_RS01935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SB89_RS01945	COG0438	transferase activity, transferring glycosyl groups
SB89_RS01955	COG2963	transposase activity
SB89_RS01960	COG2801	Transposase and inactivated derivatives
SB89_RS02010	COG1134	teichoic acid transport
SB89_RS02030	COG3547	Transposase (IS116 IS110 IS902 family)
SB89_RS02050	COG2963	transposase activity
SB89_RS02055	COG2801	Transposase and inactivated derivatives
SB89_RS02070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SB89_RS02075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SB89_RS02080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SB89_RS02085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SB89_RS02095	COG3800	Transcriptional regulator
SB89_RS02095	COG1396	sequence-specific DNA binding
SB89_RS02105	COG1053	succinate dehydrogenase
SB89_RS02110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SB89_RS02130	COG2733	membrane
SB89_RS02145	COG1309	transcriptional regulator
SB89_RS02160	COG0788	formyltetrahydrofolate deformylase activity
SB89_RS02165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SB89_RS02175	COG1937	Protein conserved in bacteria
SB89_RS02195	COG4558	Periplasmic binding protein
SB89_RS02200	COG4139	cobalamin transport
SB89_RS02205	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SB89_RS02235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SB89_RS02245	COG0318	PFAM AMP-dependent synthetase and ligase
SB89_RS02260	COG5002	protein histidine kinase activity
SB89_RS02265	COG0745	RESPONSE REGULATOR receiver
SB89_RS02275	COG0577	efflux transmembrane transporter activity
SB89_RS02315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SB89_RS02320	COG0181	hydroxymethylbilane synthase activity
SB89_RS02335	COG0477	Major facilitator Superfamily
SB89_RS02340	COG1082	Xylose isomerase domain protein TIM barrel
SB89_RS02340	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SB89_RS02345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SB89_RS02355	COG0222	ribosome binding
SB89_RS02360	COG3842	ATPase activity
SB89_RS02375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SB89_RS02375	COG1648	precorrin-2 dehydrogenase activity
SB89_RS02385	COG0113	porphobilinogen synthase activity
SB89_RS02400	COG2217	Heavy metal translocating P-type atpase
SB89_RS02415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SB89_RS02420	COG0406	alpha-ribazole phosphatase activity
SB89_RS02430	COG0785	Cytochrome C biogenesis protein
SB89_RS02435	COG1333	cytochrome c biogenesis protein
SB89_RS02440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SB89_RS02495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SB89_RS02500	COG0583	DNA-binding transcription factor activity
SB89_RS02540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SB89_RS02550	COG3340	Belongs to the peptidase S51 family
SB89_RS02555	COG4948	Mandelate Racemase Muconate Lactonizing
SB89_RS02570	COG0438	transferase activity, transferring glycosyl groups
SB89_RS02570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SB89_RS02575	COG1113	amino acid transport
SB89_RS02590	COG0142	geranyltranstransferase activity
SB89_RS02620	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SB89_RS02630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SB89_RS02690	COG0085	RNA polymerase activity
SB89_RS02715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SB89_RS02725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SB89_RS02740	COG1120	ATPase activity
SB89_RS02745	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS02750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS02755	COG0427	acetyl-CoA hydrolase
SB89_RS02860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SB89_RS02885	COG3845	ABC transporter
SB89_RS02920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SB89_RS02930	COG1841	ribosomal large subunit assembly
SB89_RS02985	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS02990	COG3848	Pyruvate phosphate dikinase
SB89_RS02990	COG0574	Belongs to the PEP-utilizing enzyme family
SB89_RS03005	COG1414	Transcriptional regulator
SB89_RS03010	COG0201	protein transport
SB89_RS03055	COG0203	ribosomal protein L17
SB89_RS03060	COG0101	tRNA pseudouridine synthase activity
SB89_RS03080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SB89_RS03090	COG1404	Belongs to the peptidase S8 family
SB89_RS03100	COG1674	ftsk spoiiie
SB89_RS03170	COG0569	domain protein
SB89_RS03170	COG2985	domain, Protein
SB89_RS03185	COG0456	acetyltransferase
SB89_RS03195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SB89_RS03195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SB89_RS03210	COG0459	protein refolding
SB89_RS03240	COG0516	GMP reductase activity
SB89_RS03250	COG0583	DNA-binding transcription factor activity
SB89_RS03255	COG0519	Catalyzes the synthesis of GMP from XMP
SB89_RS03255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SB89_RS03275	COG2197	response regulator
SB89_RS03300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SB89_RS03340	COG2409	Drug exporters of the RND superfamily
SB89_RS03360	COG0702	epimerase
SB89_RS03365	COG0415	Belongs to the DNA photolyase family
SB89_RS03380	COG0577	efflux transmembrane transporter activity
SB89_RS03380	COG1136	(ABC) transporter
SB89_RS03385	COG2011	ABC-type metal ion transport system permease component
SB89_RS03390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SB89_RS03395	COG1464	Belongs to the NlpA lipoprotein family
SB89_RS03400	COG0587	DNA-directed DNA polymerase activity
SB89_RS03425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SB89_RS03435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SB89_RS03440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SB89_RS03465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SB89_RS03470	COG2873	o-acetylhomoserine
SB89_RS03475	COG1966	Carbon starvation protein
SB89_RS03485	COG2079	MmgE PrpD family protein
SB89_RS03490	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SB89_RS03495	COG0372	Belongs to the citrate synthase family
SB89_RS03500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SB89_RS03515	COG2838	Isocitrate dehydrogenase
SB89_RS03525	COG1120	ATPase activity
SB89_RS03530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS03535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS03545	COG2814	Major facilitator Superfamily
SB89_RS03555	COG2860	membrane
SB89_RS03570	COG1120	ATPase activity
SB89_RS03575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS03580	COG0180	Tryptophanyl-tRNA synthetase
SB89_RS03585	COG1295	ribonuclease BN
SB89_RS03595	COG1686	Belongs to the peptidase S11 family
SB89_RS03605	COG0741	lytic transglycosylase activity
SB89_RS03605	COG0791	NLP P60 protein
SB89_RS03625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SB89_RS03630	COG1473	amidohydrolase
SB89_RS03630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SB89_RS03640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SB89_RS03655	COG0523	cobalamin synthesis protein
SB89_RS03660	COG0492	ferredoxin-NADP+ reductase activity
SB89_RS03665	COG2079	MmgE PrpD family protein
SB89_RS03670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SB89_RS03675	COG0372	Belongs to the citrate synthase family
SB89_RS03685	COG1396	sequence-specific DNA binding
SB89_RS03685	COG3800	Transcriptional regulator
SB89_RS03695	COG4770	biotin carboxylase activity
SB89_RS03700	COG2897	thiosulfate sulfurtransferase activity
SB89_RS03705	COG0189	ligase activity
SB89_RS03735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SB89_RS03740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SB89_RS03785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS03835	COG3842	ATPase activity
SB89_RS03860	COG0210	DNA helicase
SB89_RS03865	COG1201	RNA secondary structure unwinding
SB89_RS03875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SB89_RS03880	COG1316	TRANSCRIPTIONal
SB89_RS03920	COG1482	cell wall glycoprotein biosynthetic process
SB89_RS03945	COG0745	RESPONSE REGULATOR receiver
SB89_RS03950	COG5002	protein histidine kinase activity
SB89_RS03965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SB89_RS03980	COG1011	Hydrolase
SB89_RS03990	COG1162	GTPase activity
SB89_RS03995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SB89_RS04030	COG0513	Belongs to the DEAD box helicase family
SB89_RS04055	COG0210	DNA helicase
SB89_RS04060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SB89_RS04065	COG2816	NAD+ diphosphatase activity
SB89_RS04090	COG3480	Lon protease (S16) C-terminal proteolytic domain
SB89_RS04110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SB89_RS04115	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SB89_RS04175	COG0483	inositol monophosphate 1-phosphatase activity
SB89_RS04180	COG0483	inositol monophosphate 1-phosphatase activity
SB89_RS04190	COG2884	Cell division ATP-binding protein ftsE
SB89_RS04195	COG2177	Part of the ABC transporter FtsEX involved in
SB89_RS04205	COG3189	MarR family transcriptional regulator
SB89_RS04220	COG3833	ABC-type maltose transport systems, permease component
SB89_RS04225	COG1175	transmembrane transport
SB89_RS04260	COG2375	cellular response to nickel ion
SB89_RS04260	COG1132	(ABC) transporter
SB89_RS04265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SB89_RS04330	COG1061	Type III restriction enzyme res subunit
SB89_RS04345	COG1652	LysM domain
SB89_RS04370	COG2252	PERMEase
SB89_RS04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SB89_RS04395	COG0372	Belongs to the citrate synthase family
SB89_RS04400	COG0545	Peptidyl-prolyl cis-trans isomerase
SB89_RS04415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SB89_RS04425	COG3757	hydrolase, family 25
SB89_RS04430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SB89_RS04445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SB89_RS04465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SB89_RS04480	COG1218	3'(2'),5'-bisphosphate nucleotidase
SB89_RS04485	COG1201	RNA secondary structure unwinding
SB89_RS04490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SB89_RS04495	COG3304	Inner membrane component domain
SB89_RS04500	COG0586	Pfam SNARE associated Golgi protein
SB89_RS04510	COG0166	Belongs to the GPI family
SB89_RS04520	COG1605	Chorismate mutase
SB89_RS04535	COG1136	(ABC) transporter
SB89_RS04535	COG0577	efflux transmembrane transporter activity
SB89_RS04545	COG0739	heme binding
SB89_RS04565	COG0138	bifunctional purine biosynthesis protein purh
SB89_RS04575	COG1309	transcriptional regulator
SB89_RS04605	COG0659	secondary active sulfate transmembrane transporter activity
SB89_RS04625	COG0745	RESPONSE REGULATOR receiver
SB89_RS04635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SB89_RS04655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SB89_RS04660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SB89_RS04680	COG2807	transmembrane transport
SB89_RS04700	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
SB89_RS04710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SB89_RS04715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SB89_RS04725	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SB89_RS04745	COG2801	Transposase and inactivated derivatives
SB89_RS04755	COG0277	FAD linked oxidase domain protein
SB89_RS04775	COG2801	Transposase and inactivated derivatives
SB89_RS04790	COG0084	hydrolase, TatD family'
SB89_RS04795	COG3583	domain protein
SB89_RS04810	COG0488	(ABC) transporter
SB89_RS04835	COG2326	polyphosphate kinase activity
SB89_RS04840	COG0561	phosphatase activity
SB89_RS04860	COG5479	isomerase activity
SB89_RS04860	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SB89_RS04870	COG2409	Drug exporters of the RND superfamily
SB89_RS04875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SB89_RS04895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SB89_RS04915	COG0411	ABC transporter
SB89_RS04925	COG0193	aminoacyl-tRNA hydrolase activity
SB89_RS04940	COG0193	aminoacyl-tRNA hydrolase activity
SB89_RS04960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SB89_RS04965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SB89_RS04975	COG2132	Multicopper oxidase
SB89_RS04980	COG1131	(ABC) transporter
SB89_RS04990	COG4585	Histidine kinase
SB89_RS04995	COG2909	trisaccharide binding
SB89_RS05010	COG1132	(ABC) transporter
SB89_RS05015	COG1132	(ABC) transporter
SB89_RS05020	COG0405	Gamma-glutamyltransferase
SB89_RS05060	COG1309	transcriptional regulator
SB89_RS05080	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SB89_RS05085	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SB89_RS05090	COG0531	amino acid
SB89_RS05100	COG3956	TIGRFAM MazG family protein
SB89_RS05150	COG2207	Transcriptional regulator
SB89_RS05175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SB89_RS05185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SB89_RS05195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SB89_RS05200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SB89_RS05255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SB89_RS05265	COG2188	Transcriptional regulator
SB89_RS05275	COG0114	fumarate hydratase activity
SB89_RS05295	COG1960	acyl-CoA dehydrogenase activity
SB89_RS05310	COG1494	fructose-1,6-bisphosphatase
SB89_RS05340	COG1570	exodeoxyribonuclease VII activity
SB89_RS05355	COG0628	permease
SB89_RS05365	COG0733	neurotransmitter:sodium symporter activity
SB89_RS05375	COG0012	GTP binding
SB89_RS05415	COG2801	Transposase and inactivated derivatives
SB89_RS05465	COG2814	Major facilitator Superfamily
SB89_RS05540	COG0488	(ABC) transporter
SB89_RS05550	COG2824	Alkylphosphonate utilization operon protein PhnA
SB89_RS05560	COG2814	Major facilitator Superfamily
SB89_RS05565	COG1104	cysteine desulfurase activity
SB89_RS05575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SB89_RS05590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SB89_RS05595	COG2315	Protein conserved in bacteria
SB89_RS05600	COG0095	Lipoate-protein ligase
SB89_RS05610	COG2814	Major facilitator Superfamily
SB89_RS05620	COG4721	ABC-type cobalt transport system, permease component
SB89_RS05625	COG1122	ATPase activity
SB89_RS05640	COG0387	Pfam Sodium calcium exchanger
SB89_RS05655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SB89_RS05660	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SB89_RS05670	COG2354	Protein conserved in bacteria
SB89_RS05675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SB89_RS05685	COG0494	nUDIX hydrolase
SB89_RS05705	COG3949	Membrane
SB89_RS05720	COG1217	gtp-binding protein TYPA
SB89_RS05725	COG0747	negative chemotaxis
SB89_RS05760	COG2171	N-acyltransferase activity
SB89_RS05765	COG1113	amino acid transport
SB89_RS05775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SB89_RS05785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SB89_RS05790	COG0463	Glycosyl transferase, family 2
SB89_RS05815	COG0297	glycogen (starch) synthase activity
SB89_RS05825	COG4122	O-methyltransferase activity
SB89_RS05830	COG1595	DNA-templated transcription, initiation
SB89_RS05875	COG0508	dehydrogenase complex catalyzes the overall conversion of
SB89_RS05875	COG0567	Dehydrogenase, E1 component
SB89_RS05880	COG1132	(ABC) transporter
SB89_RS05890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SB89_RS05895	COG2272	Belongs to the type-B carboxylesterase lipase family
SB89_RS05915	COG2814	Major facilitator Superfamily
SB89_RS05975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SB89_RS05980	COG4988	ABC transporter
SB89_RS05985	COG1294	oxidase, subunit
SB89_RS05990	COG1271	oxidase subunit
SB89_RS06050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SB89_RS06055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SB89_RS06075	COG0657	acetylesterase activity
SB89_RS06085	COG2353	YceI-like domain
SB89_RS06090	COG1846	Transcriptional regulator
SB89_RS06105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SB89_RS06110	COG2217	Heavy metal translocating P-type atpase
SB89_RS06120	COG2357	RelA SpoT domain protein
SB89_RS06140	COG0019	diaminopimelate decarboxylase activity
SB89_RS06195	COG2826	transposase and inactivated derivatives, IS30 family
SB89_RS06200	COG0315	cyclic pyranopterin monophosphate synthase activity
SB89_RS06200	COG0521	Mo-molybdopterin cofactor biosynthetic process
SB89_RS06210	COG1253	flavin adenine dinucleotide binding
SB89_RS06220	COG0746	molybdenum cofactor guanylyltransferase activity
SB89_RS06230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SB89_RS06275	COG0356	it plays a direct role in the translocation of protons across the membrane
SB89_RS06280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SB89_RS06285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SB89_RS06295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SB89_RS06300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SB89_RS06310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SB89_RS06330	COG0346	lactoylglutathione lyase activity
SB89_RS06345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS06350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SB89_RS06355	COG1116	anion transmembrane transporter activity
SB89_RS06360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SB89_RS06365	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SB89_RS06370	COG0366	Alpha amylase catalytic
SB89_RS06375	COG1119	ATPase activity
SB89_RS06400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SB89_RS06405	COG1104	cysteine desulfurase activity
SB89_RS06420	COG1396	sequence-specific DNA binding
SB89_RS06480	COG0154	amidase activity
SB89_RS06495	COG0205	6-phosphofructokinase activity
SB89_RS06500	COG1609	Transcriptional regulator
SB89_RS06505	COG1129	ABC transporter
SB89_RS06525	COG0385	Bile acid
SB89_RS06540	COG0667	Aldo Keto reductase
SB89_RS06545	COG1279	arginine transmembrane transporter activity
SB89_RS06550	COG0583	DNA-binding transcription factor activity
SB89_RS06555	COG0435	Glutathione S-transferase
SB89_RS06570	COG0129	dihydroxy-acid dehydratase activity
SB89_RS06580	COG0668	transmembrane transport
SB89_RS06585	COG0028	Belongs to the TPP enzyme family
SB89_RS06590	COG0440	acetolactate synthase activity
SB89_RS06600	COG1116	anion transmembrane transporter activity
SB89_RS06605	COG1116	anion transmembrane transporter activity
SB89_RS06630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SB89_RS06660	COG0473	3-isopropylmalate dehydrogenase activity
SB89_RS06680	COG0179	Fumarylacetoacetate (FAA) hydrolase
SB89_RS06700	COG3655	Transcriptional regulator
SB89_RS06765	COG0058	SHG alpha-glucan phosphorylase activity
SB89_RS06775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SB89_RS06790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SB89_RS06800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SB89_RS06810	COG0494	nUDIX hydrolase
SB89_RS06810	COG0406	alpha-ribazole phosphatase activity
SB89_RS06835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SB89_RS06840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SB89_RS06845	COG1461	Dihydroxyacetone kinase
SB89_RS06850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SB89_RS06860	COG0742	ribosomal rna small subunit methyltransferase
SB89_RS06880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SB89_RS06915	COG2801	Transposase and inactivated derivatives
SB89_RS06920	COG2963	transposase activity
SB89_RS06995	COG0656	L-ascorbic acid biosynthetic process
SB89_RS07010	COG0539	negative regulation of cytoplasmic translation
SB89_RS07015	COG1263	PTS System
SB89_RS07015	COG2190	(PTS) system
SB89_RS07015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SB89_RS07025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SB89_RS07045	COG0477	Major facilitator Superfamily
SB89_RS07050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SB89_RS07055	COG1609	Transcriptional regulator
SB89_RS07080	COG1733	regulation of RNA biosynthetic process
SB89_RS07085	COG0702	epimerase
SB89_RS07090	COG3973	AAA domain
SB89_RS07140	COG4209	transmembrane transport
SB89_RS07155	COG3842	ATPase activity
SB89_RS07165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SB89_RS07170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SB89_RS07175	COG0072	phenylalanine-tRNA ligase activity
SB89_RS07175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SB89_RS07195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SB89_RS07210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SB89_RS07215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SB89_RS07225	COG0137	argininosuccinate synthase activity
SB89_RS07245	COG2835	tetraacyldisaccharide 4'-kinase activity
SB89_RS07250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SB89_RS07280	COG0647	UMP catabolic process
SB89_RS07295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SB89_RS07320	COG0494	nUDIX hydrolase
SB89_RS07325	COG4974	Belongs to the 'phage' integrase family
SB89_RS07330	COG0488	(ABC) transporter
SB89_RS07340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SB89_RS07350	COG2897	thiosulfate sulfurtransferase activity
SB89_RS07355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SB89_RS07365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SB89_RS07370	COG1160	GTP binding
SB89_RS07395	COG1132	(ABC) transporter
SB89_RS07400	COG0428	transporter
SB89_RS07405	COG0025	NhaP-type Na H and K H
SB89_RS07420	COG3012	SEC-C Motif Domain Protein
SB89_RS07430	COG0653	protein targeting
SB89_RS07435	COG1716	ATPase activity
SB89_RS07470	COG1253	flavin adenine dinucleotide binding
SB89_RS07475	COG1253	flavin adenine dinucleotide binding
SB89_RS07480	COG0513	Belongs to the DEAD box helicase family
SB89_RS07490	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SB89_RS07510	COG0842	Transport permease protein
SB89_RS07520	COG3639	organic phosphonate transmembrane transporter activity
SB89_RS07525	COG3639	organic phosphonate transmembrane transporter activity
SB89_RS07530	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SB89_RS07545	COG0351	phosphomethylpyrimidine kinase
SB89_RS07545	COG0352	thiamine-phosphate diphosphorylase activity
SB89_RS07545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SB89_RS07550	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SB89_RS07555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SB89_RS07565	COG0477	Major facilitator Superfamily
SB89_RS07570	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SB89_RS07595	COG0659	secondary active sulfate transmembrane transporter activity
SB89_RS07625	COG0463	Glycosyl transferase, family 2
SB89_RS07690	COG0805	protein transport
SB89_RS07695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SB89_RS07720	COG4122	O-methyltransferase activity
SB89_RS07735	COG1362	aminopeptidase activity
SB89_RS07750	COG2814	Major facilitator Superfamily
SB89_RS07755	COG1027	Aspartate ammonia-lyase
SB89_RS07770	COG0546	phosphoglycolate phosphatase activity
SB89_RS07775	COG0646	methionine synthase
SB89_RS07775	COG1410	methionine synthase
SB89_RS07785	COG2072	flavoprotein involved in K transport
SB89_RS07790	COG0798	PFAM Bile acid sodium symporter
SB89_RS07795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SB89_RS07800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SB89_RS07815	COG1968	undecaprenyl-diphosphatase activity
SB89_RS07820	COG0667	Aldo Keto reductase
SB89_RS07845	COG1881	PFAM PEBP family protein
SB89_RS07850	COG1132	(ABC) transporter
SB89_RS07855	COG1132	(ABC) transporter
SB89_RS07925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SB89_RS07930	COG3883	PFAM NLP P60 protein
SB89_RS07930	COG0791	NLP P60 protein
SB89_RS07940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SB89_RS07945	COG1309	transcriptional regulator
SB89_RS07965	COG3830	Belongs to the UPF0237 family
SB89_RS07970	COG2848	UPF0210 protein
SB89_RS07975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SB89_RS07995	COG0488	(ABC) transporter
SB89_RS08020	COG0822	iron-sulfur transferase activity
SB89_RS08030	COG0396	ATPase activity
SB89_RS08085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SB89_RS08090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SB89_RS08115	COG2423	ornithine cyclodeaminase activity
SB89_RS08120	COG0004	ammonium transporteR
SB89_RS08125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SB89_RS08130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SB89_RS08135	COG0149	triose-phosphate isomerase activity
SB89_RS08140	COG0126	phosphoglycerate kinase activity
SB89_RS08145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SB89_RS08150	COG1481	regulation of sporulation
SB89_RS08165	COG0322	excinuclease ABC activity
SB89_RS08210	COG0242	peptide deformylase activity
SB89_RS08220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SB89_RS08230	COG1758	RNA polymerase activity
SB89_RS08235	COG0194	GDP metabolic process
SB89_RS08250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SB89_RS08255	COG0505	Belongs to the CarA family
SB89_RS08260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SB89_RS08265	COG0540	Belongs to the ATCase OTCase family
SB89_RS08270	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SB89_RS08295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SB89_RS08305	COG0006	proline dipeptidase activity
SB89_RS08310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SB89_RS08315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SB89_RS08320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SB89_RS08325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SB89_RS08335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS08345	COG1120	ATPase activity
SB89_RS08350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SB89_RS08355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SB89_RS08360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SB89_RS08390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SB89_RS08415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS08425	COG1760	l-serine dehydratase
SB89_RS08430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SB89_RS08435	COG0124	histidyl-tRNA synthetase
SB89_RS08445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SB89_RS08460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SB89_RS08465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SB89_RS08470	COG0747	negative chemotaxis
SB89_RS08475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SB89_RS08480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SB89_RS08495	COG0632	four-way junction helicase activity
SB89_RS08500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SB89_RS08505	COG0217	transcriptional regulatory protein
SB89_RS08510	COG1946	Acyl-CoA thioesterase
SB89_RS08525	COG0438	transferase activity, transferring glycosyl groups
SB89_RS08530	COG1560	Kdo2-lipid A biosynthetic process
SB89_RS08535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SB89_RS08545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SB89_RS08550	COG2837	iron assimilation
SB89_RS08555	COG2847	Copper chaperone PCu(A)C
SB89_RS08600	COG1929	Belongs to the glycerate kinase type-1 family
SB89_RS08620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SB89_RS08625	COG3253	May function as heme-dependent peroxidase
SB89_RS08635	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SB89_RS08645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SB89_RS08655	COG0756	dUTP diphosphatase activity
SB89_RS08675	COG0483	inositol monophosphate 1-phosphatase activity
SB89_RS08690	COG2311	Membrane
SB89_RS08700	COG1061	Type III restriction enzyme res subunit
SB89_RS08730	COG1321	iron dependent repressor
SB89_RS08735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SB89_RS08755	COG0583	DNA-binding transcription factor activity
SB89_RS08765	COG1643	Atp-dependent helicase
SB89_RS08785	COG1349	DNA-binding transcription factor activity
SB89_RS08795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SB89_RS08805	COG1105	Belongs to the carbohydrate kinase PfkB family
SB89_RS08810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SB89_RS08810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SB89_RS08810	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SB89_RS08825	COG2233	PERMEase
SB89_RS08830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SB89_RS08845	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SB89_RS08850	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SB89_RS08860	COG1196	nuclear chromosome segregation
SB89_RS08880	COG1126	abc transporter atp-binding protein
SB89_RS08885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SB89_RS08890	COG0765	amino acid transport
SB89_RS08895	COG0765	amino acid transport
SB89_RS08900	COG2137	regulation of response to DNA damage stimulus
SB89_RS08920	COG1268	BioY protein
SB89_RS08925	COG1122	ATPase activity
SB89_RS08935	COG1842	Phage shock protein A
SB89_RS08940	COG1396	sequence-specific DNA binding
SB89_RS08965	COG1674	ftsk spoiiie
SB89_RS08975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SB89_RS08980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SB89_RS08985	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SB89_RS09000	COG1185	polyribonucleotide nucleotidyltransferase activity
SB89_RS09030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SB89_RS09040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SB89_RS09045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SB89_RS09075	COG4166	transmembrane transport
SB89_RS09085	COG0601	transmembrane transport
SB89_RS09090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SB89_RS09095	COG4172	Belongs to the ABC transporter superfamily
SB89_RS09100	COG0442	prolyl-tRNA aminoacylation
SB89_RS09105	COG3022	response to hydroperoxide
SB89_RS09125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SB89_RS09165	COG2197	response regulator
SB89_RS09170	COG3850	Histidine kinase
SB89_RS09175	COG0577	efflux transmembrane transporter activity
SB89_RS09180	COG0577	efflux transmembrane transporter activity
SB89_RS09180	COG1136	(ABC) transporter
SB89_RS09195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SB89_RS09200	COG0750	zinc metalloprotease
SB89_RS09220	COG1131	(ABC) transporter
SB89_RS09225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SB89_RS09240	COG0233	cytoplasmic translational termination
SB89_RS09250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SB89_RS09265	COG4974	Belongs to the 'phage' integrase family
SB89_RS09275	COG0606	chelatase, subunit chli
SB89_RS09280	COG0792	nuclease activity
SB89_RS09290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SB89_RS09295	COG0681	Belongs to the peptidase S26 family
SB89_RS09310	COG0352	thiamine-phosphate diphosphorylase activity
SB89_RS09315	COG2022	thiamine diphosphate biosynthetic process
SB89_RS09315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SB89_RS09330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SB89_RS09340	COG1609	Transcriptional regulator
SB89_RS09345	COG0471	metal ion transport
SB89_RS09365	COG0336	Belongs to the RNA methyltransferase TrmD family
SB89_RS09375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SB89_RS09410	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SB89_RS09445	COG1254	Belongs to the acylphosphatase family
SB89_RS09475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SB89_RS09480	COG0571	ribonuclease III activity
SB89_RS09495	COG1132	(ABC) transporter
SB89_RS09500	COG1132	(ABC) transporter
SB89_RS09505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SB89_RS09510	COG1929	Belongs to the glycerate kinase type-1 family
SB89_RS09540	COG0058	SHG alpha-glucan phosphorylase activity
SB89_RS09545	COG2514	catechol 2,3-dioxygenase activity
SB89_RS09550	COG0469	pyruvate kinase activity
SB89_RS09560	COG0134	indole-3-glycerol-phosphate synthase activity
SB89_RS09570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SB89_RS09580	COG0483	inositol monophosphate 1-phosphatase activity
SB89_RS09585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SB89_RS09590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SB89_RS09615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SB89_RS09645	COG2264	protein methyltransferase activity
SB89_RS09655	COG0673	inositol 2-dehydrogenase activity
SB89_RS09660	COG1609	Transcriptional regulator
SB89_RS09665	COG1120	ATPase activity
SB89_RS09670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SB89_RS09720	COG1739	Uncharacterized protein family UPF0029
SB89_RS09730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SB89_RS09765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SB89_RS09775	COG0488	(ABC) transporter
SB89_RS09785	COG0252	asparaginase activity
SB89_RS09815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SB89_RS09825	COG3599	regulation of cell shape
SB89_RS09835	COG1799	cell septum assembly
SB89_RS09840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SB89_RS09845	COG1496	oxidoreductase activity
SB89_RS09850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SB89_RS09855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SB89_RS09865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SB89_RS09875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SB89_RS09890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SB89_RS09895	COG0768	penicillin binding
SB89_RS09905	COG0275	rRNA processing
SB89_RS09925	COG0456	acetyltransferase
SB89_RS09935	COG0142	geranyltranstransferase activity
SB89_RS09950	COG0515	serine threonine protein kinase
SB89_RS09950	COG2815	serine threonine protein kinase
SB89_RS09955	COG5650	phosphatidylinositol metabolic process
SB89_RS09965	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SB89_RS09980	COG5479	isomerase activity
SB89_RS09980	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SB89_RS10000	COG1940	carbohydrate kinase activity
SB89_RS10005	COG0438	transferase activity, transferring glycosyl groups
SB89_RS10020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SB89_RS10025	COG0723	plastoquinol--plastocyanin reductase activity
SB89_RS10030	COG2010	Cytochrome c
SB89_RS10035	COG1845	cytochrome c oxidase, subunit III
SB89_RS10050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SB89_RS10090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SB89_RS10095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SB89_RS10105	COG0508	dehydrogenase complex catalyzes the overall conversion of
SB89_RS10125	COG2985	domain, Protein
SB89_RS10125	COG0569	domain protein
SB89_RS10135	COG0174	glutamine synthetase
SB89_RS10155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS10165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SB89_RS10195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SB89_RS10200	COG0174	glutamine synthetase
SB89_RS10235	COG1136	(ABC) transporter
SB89_RS10235	COG0577	efflux transmembrane transporter activity
SB89_RS10250	COG1132	(ABC) transporter
SB89_RS10275	COG3323	Protein of unknown function (DUF1653)
SB89_RS10275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SB89_RS10280	COG0546	phosphoglycolate phosphatase activity
SB89_RS10320	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SB89_RS10330	COG4120	Belongs to the binding-protein-dependent transport system permease family
SB89_RS10350	COG0596	Alpha beta hydrolase
SB89_RS10355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SB89_RS10485	COG3387	PFAM Glycoside hydrolase 15-related
SB89_RS10510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SB89_RS10520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SB89_RS10555	COG0423	glycine-tRNA ligase activity
SB89_RS10580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SB89_RS10590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SB89_RS10615	COG0484	heat shock protein binding
SB89_RS10655	COG1132	(ABC) transporter
SB89_RS10675	COG0366	Alpha amylase catalytic
SB89_RS10710	COG1114	Component of the transport system for branched-chain amino acids
SB89_RS10715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS10720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SB89_RS10735	COG0277	FAD linked oxidase domain protein
SB89_RS10735	COG0247	lactate metabolic process
SB89_RS10760	COG0747	negative chemotaxis
SB89_RS10765	COG0601	transmembrane transport
SB89_RS10770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SB89_RS10785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SB89_RS10800	COG0676	glucose-6-phosphate 1-epimerase activity
SB89_RS10805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SB89_RS10810	COG2224	Isocitrate lyase
SB89_RS10825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SB89_RS10855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SB89_RS10865	COG0481	GTPase activity
SB89_RS10880	COG1280	lysine exporter protein (LysE YggA)
SB89_RS10905	COG1307	EDD domain protein, DegV family
SB89_RS10910	COG0406	alpha-ribazole phosphatase activity
SB89_RS10920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SB89_RS10935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SB89_RS10940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SB89_RS10945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SB89_RS10980	COG1530	ribonuclease E activity
SB89_RS11025	COG0285	dihydrofolate synthase activity
SB89_RS11030	COG0525	valine-tRNA ligase activity
SB89_RS11040	COG0443	Heat shock 70 kDa protein
SB89_RS11050	COG0039	L-malate dehydrogenase activity
SB89_RS11055	COG1309	transcriptional regulator
SB89_RS11075	COG2814	Major facilitator Superfamily
SB89_RS11105	COG1414	Transcriptional regulator
SB89_RS11110	COG0183	Belongs to the thiolase family
SB89_RS11115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SB89_RS11130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SB89_RS11135	COG3485	protocatechuate 3,4-dioxygenase
SB89_RS11140	COG3485	protocatechuate 3,4-dioxygenase
SB89_RS11150	COG4829	muconolactone delta-isomerase
SB89_RS11155	COG4948	Mandelate Racemase Muconate Lactonizing
SB89_RS11160	COG3485	protocatechuate 3,4-dioxygenase
SB89_RS11165	COG4638	Rieske (2fe-2S)
SB89_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS11190	COG2814	Major facilitator Superfamily
SB89_RS11200	COG0740	serine-type endopeptidase activity
SB89_RS11205	COG0740	serine-type endopeptidase activity
SB89_RS11270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SB89_RS11305	COG4172	Belongs to the ABC transporter superfamily
SB89_RS11310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SB89_RS11315	COG0601	transmembrane transport
SB89_RS11320	COG0747	negative chemotaxis
SB89_RS11330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SB89_RS11345	COG4221	oxidoreductase activity
SB89_RS11360	COG1119	ATPase activity
SB89_RS11365	COG0668	transmembrane transport
SB89_RS11460	COG3842	ATPase activity
SB89_RS11465	COG0463	Glycosyl transferase, family 2
SB89_RS11505	COG1335	isochorismatase
SB89_RS11510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS11515	COG1606	tRNA processing
SB89_RS11520	COG1691	(AIR) carboxylase
SB89_RS11530	COG3622	Belongs to the hyi family
SB89_RS11535	COG4221	oxidoreductase activity
SB89_RS11550	COG1376	ErfK ybiS ycfS ynhG family protein
SB89_RS11590	COG2066	Belongs to the glutaminase family
SB89_RS11605	COG1904	glucuronate isomerase
SB89_RS11605	COG1102	Psort location Cytoplasmic, score
SB89_RS11610	COG3265	gluconokinase activity
SB89_RS11620	COG1335	isochorismatase
SB89_RS11645	COG2814	Major facilitator Superfamily
SB89_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
SB89_RS11685	COG3835	regulator
SB89_RS11695	COG3311	Transcriptional regulator
SB89_RS11700	COG1569	PIN domain
SB89_RS11740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SB89_RS11745	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SB89_RS11755	COG1234	tRNA 3'-trailer cleavage
SB89_RS11760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SB89_RS11780	COG3191	aminopeptidase activity
SB89_RS11800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SB89_RS11825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SB89_RS11855	COG2186	Transcriptional regulator
SB89_RS11870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SB89_RS11890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SB89_RS11905	COG0604	alcohol dehydrogenase
SB89_RS11920	COG0033	Phosphoglucomutase
SB89_RS11925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SB89_RS11930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SB89_RS11955	COG1136	(ABC) transporter
SB89_RS12005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SB89_RS12015	COG2197	response regulator
SB89_RS12025	COG1045	serine acetyltransferase
SB89_RS12050	COG0045	succinate-CoA ligase (ADP-forming) activity
SB89_RS12065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SB89_RS12095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SB89_RS12115	COG0456	acetyltransferase
SB89_RS12125	COG1597	lipid kinase activity
SB89_RS12140	COG0354	folic acid binding
SB89_RS12150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SB89_RS12175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SB89_RS12180	COG0047	phosphoribosylformylglycinamidine synthase activity
SB89_RS12185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SB89_RS12190	COG0386	Belongs to the glutathione peroxidase family
SB89_RS12215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SB89_RS12225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SB89_RS12230	COG0436	Aminotransferase
SB89_RS12235	COG0151	Belongs to the GarS family
SB89_RS12240	COG0537	adenosine 5'-monophosphoramidase activity
SB89_RS12245	COG2226	methyltransferase
SB89_RS12245	COG2267	carboxylic ester hydrolase activity
SB89_RS12250	COG3104	oligopeptide transport
SB89_RS12255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SB89_RS12260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SB89_RS12265	COG2205	protein histidine kinase activity
SB89_RS12270	COG0745	RESPONSE REGULATOR receiver
SB89_RS12275	COG0789	Transcriptional regulator
SB89_RS12285	COG0028	Belongs to the TPP enzyme family
SB89_RS12295	COG1309	transcriptional regulator
SB89_RS12310	COG1053	succinate dehydrogenase
SB89_RS12315	COG1053	succinate dehydrogenase
SB89_RS12330	COG0477	Major facilitator Superfamily
SB89_RS12335	COG0583	DNA-binding transcription factor activity
SB89_RS12340	COG1748	Saccharopine dehydrogenase
SB89_RS12380	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SB89_RS12395	COG1609	Transcriptional regulator
SB89_RS12405	COG1121	(ABC) transporter
SB89_RS12410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SB89_RS12415	COG1053	succinate dehydrogenase
SB89_RS12430	COG0477	Major facilitator Superfamily
SB89_RS12440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SB89_RS12455	COG1621	beta-fructofuranosidase activity
SB89_RS12465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SB89_RS12470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SB89_RS12515	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SB89_RS12520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SB89_RS12535	COG2205	protein histidine kinase activity
SB89_RS12540	COG2847	Copper chaperone PCu(A)C
SB89_RS12545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SB89_RS12550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SB89_RS12605	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SB89_RS12610	COG0714	Associated with various cellular activities
SB89_RS12620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SB89_RS12640	COG2207	Transcriptional regulator
SB89_RS12655	COG2814	Major facilitator Superfamily
SB89_RS12660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SB89_RS12665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SB89_RS12685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SB89_RS12700	COG0302	gtp cyclohydrolase
SB89_RS12705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SB89_RS12715	COG0037	tRNA processing
SB89_RS12720	COG2027	D-alanyl-D-alanine carboxypeptidase
SB89_RS12725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SB89_RS12730	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SB89_RS12735	COG3766	membrane
SB89_RS12760	COG2190	(PTS) system
SB89_RS12760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SB89_RS12760	COG1263	PTS System
SB89_RS12770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SB89_RS12785	COG1012	belongs to the aldehyde dehydrogenase family
SB89_RS12790	COG2326	polyphosphate kinase activity
SB89_RS12810	COG1100	Small GTP-binding protein
SB89_RS12860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SB89_RS12860	COG2111	Na H antiporter
SB89_RS12865	COG1006	Multisubunit Na H antiporter MnhC subunit
SB89_RS12870	COG0651	ATP synthesis coupled electron transport
SB89_RS12880	COG2212	antiporter activity
SB89_RS12885	COG1320	monovalent cation:proton antiporter activity
SB89_RS12910	COG0242	peptide deformylase activity
SB89_RS12925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SB89_RS12930	COG2814	Major facilitator Superfamily
SB89_RS12950	COG1131	(ABC) transporter
SB89_RS12970	COG0515	serine threonine protein kinase
SB89_RS12975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SB89_RS12980	COG0280	phosphate acetyltransferase
SB89_RS13025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SB89_RS13030	COG4129	membrane
SB89_RS13035	COG0191	fructose-bisphosphate aldolase activity
SB89_RS13050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SB89_RS13060	COG2897	thiosulfate sulfurtransferase activity
SB89_RS13080	COG0542	response to heat
SB89_RS13090	COG0640	Transcriptional regulator
SB89_RS13160	COG1012	belongs to the aldehyde dehydrogenase family
SB89_RS13165	COG0789	Transcriptional regulator
SB89_RS13170	COG0484	heat shock protein binding
SB89_RS13175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SB89_RS13180	COG0443	Heat shock 70 kDa protein
SB89_RS13235	COG0730	response to heat
SB89_RS13260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SB89_RS13305	COG1162	GTPase activity
SB89_RS13315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SB89_RS13325	COG1122	ATPase activity
SB89_RS13360	COG2818	Glycosylase
SB89_RS13365	COG1017	nitric oxide dioxygenase activity
SB89_RS13365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SB89_RS13375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SB89_RS13410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SB89_RS13435	COG1472	Belongs to the glycosyl hydrolase 3 family
SB89_RS13450	COG4981	capsule polysaccharide biosynthetic process
SB89_RS13475	COG0438	transferase activity, transferring glycosyl groups
SB89_RS13485	COG0500	methyltransferase
SB89_RS13490	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SB89_RS13530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SB89_RS13535	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SB89_RS13535	COG3321	synthase
SB89_RS13535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SB89_RS13540	COG0318	PFAM AMP-dependent synthetase and ligase
SB89_RS13545	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
SB89_RS13570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SB89_RS13575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SB89_RS13580	COG0671	phosphoesterase, PA-phosphatase related
SB89_RS13585	COG1216	Glycosyl transferase, family 2
SB89_RS13595	COG0671	phosphoesterase, PA-phosphatase related
SB89_RS13625	COG0561	phosphatase activity
SB89_RS13635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SB89_RS13640	COG2188	Transcriptional regulator
SB89_RS13665	COG0077	Prephenate dehydratase
SB89_RS13685	COG1316	TRANSCRIPTIONal
SB89_RS13715	COG2610	gluconate transmembrane transporter activity
SB89_RS13720	COG0469	pyruvate kinase activity
SB89_RS13725	COG0039	L-malate dehydrogenase activity
SB89_RS13745	COG2188	Transcriptional regulator
SB89_RS13750	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SB89_RS13755	COG0477	Major facilitator Superfamily
SB89_RS13810	COG0583	DNA-binding transcription factor activity
SB89_RS13815	COG2814	Major facilitator Superfamily
SB89_RS13855	COG2197	response regulator
SB89_RS13875	COG3764	Sortase (surface protein transpeptidase)
SB89_RS13880	COG0706	membrane insertase activity
SB89_RS13900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SB89_RS13940	COG1842	Phage shock protein A
SB89_RS14020	COG2217	Heavy metal translocating P-type atpase
SB89_RS14030	COG2205	protein histidine kinase activity
SB89_RS14035	COG0745	RESPONSE REGULATOR receiver
SB89_RS14140	COG0739	heme binding
SB89_RS14190	COG0789	Transcriptional regulator
SB89_RS14210	COG0531	amino acid
SB89_RS14215	COG2132	Multicopper oxidase
SB89_RS14225	COG2801	Transposase and inactivated derivatives
SB89_RS14235	COG2608	mercury ion transmembrane transporter activity
SB89_RS14255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SB89_RS14265	COG0477	Major facilitator Superfamily
SB89_RS14275	COG1695	Transcriptional regulator
SB89_RS14285	COG0305	Participates in initiation and elongation during chromosome replication
SB89_RS14295	COG0629	single-stranded DNA binding
SB89_RS14300	COG0360	Binds together with S18 to 16S ribosomal RNA
SB89_RS14315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SB89_RS14325	COG1846	Transcriptional regulator
SB89_RS14360	COG1136	(ABC) transporter
SB89_RS14370	COG1260	myo-inositol-1-phosphate synthase
SB89_RS14380	COG4868	Belongs to the UPF0371 family
SB89_RS14385	COG0783	Belongs to the Dps family
SB89_RS14390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SB89_RS14395	COG1690	Belongs to the RtcB family
SB89_RS14400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SB89_RS14440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SB89_RS14445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SB89_RS14460	COG0778	Nitroreductase
SB89_RS14475	COG2832	Protein of unknown function (DUF454)
SB89_RS14490	COG0179	Fumarylacetoacetate (FAA) hydrolase
SB89_RS14505	COG2814	Major facilitator Superfamily
SB89_RS14510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SB89_RS14535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SB89_RS14540	COG0512	Glutamine amidotransferase of anthranilate synthase
SB89_RS14550	COG0134	indole-3-glycerol-phosphate synthase activity
SB89_RS14550	COG0135	phosphoribosylanthranilate isomerase activity
SB89_RS14555	COG0133	tryptophan synthase activity
SB89_RS14560	COG0159	tryptophan synthase activity
SB89_RS14570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SB89_RS14575	COG1131	(ABC) transporter
SB89_RS14610	COG1902	pentaerythritol trinitrate reductase activity
SB89_RS14645	COG3104	oligopeptide transport
SB89_RS14650	COG1309	transcriptional regulator
SB89_RS14660	COG1454	alcohol dehydrogenase
SB89_RS14665	COG2814	Major facilitator Superfamily
SB89_RS14670	COG1414	Transcriptional regulator
SB89_RS14675	COG0673	inositol 2-dehydrogenase activity
SB89_RS14685	COG0673	inositol 2-dehydrogenase activity
SB89_RS14690	COG0673	inositol 2-dehydrogenase activity
SB89_RS14700	COG0477	Major facilitator Superfamily
SB89_RS14725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SB89_RS14745	COG0351	phosphomethylpyrimidine kinase
SB89_RS14760	COG1687	branched-chain amino acid
SB89_RS14765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SB89_RS14770	COG1678	Uncharacterized ACR, COG1678
SB89_RS14775	COG0617	tRNA 3'-terminal CCA addition
SB89_RS14795	COG1595	DNA-templated transcription, initiation
SB89_RS14805	COG3118	belongs to the thioredoxin family
SB89_RS14810	COG0860	N-Acetylmuramoyl-L-alanine amidase
SB89_RS14810	COG3409	Peptidoglycan-binding domain 1 protein
SB89_RS14825	COG1192	Involved in chromosome partitioning
SB89_RS14840	COG0594	ribonuclease P activity
SB89_RS14940	COG0438	transferase activity, transferring glycosyl groups
SB89_RS14955	COG0745	RESPONSE REGULATOR receiver
SB89_RS14995	COG2190	(PTS) system
SB89_RS14995	COG1263	PTS System
SB89_RS14995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity