locus-tag	class	description
N24_RS00015	COG0592	DNA-directed DNA polymerase activity
N24_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N24_RS00030	COG0187	DNA topoisomerase II activity
N24_RS00085	COG2855	membrane
N24_RS00090	COG0583	DNA-binding transcription factor activity
N24_RS00130	COG0803	Belongs to the bacterial solute-binding protein 9 family
N24_RS00135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N24_RS00140	COG1120	ATPase activity
N24_RS00150	COG1172	Belongs to the binding-protein-dependent transport system permease family
N24_RS00175	COG2207	Transcriptional regulator
N24_RS00185	COG4592	Periplasmic binding protein
N24_RS00190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS00195	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS00200	COG1120	ATPase activity
N24_RS00220	COG0515	serine threonine protein kinase
N24_RS00220	COG2815	serine threonine protein kinase
N24_RS00225	COG0515	serine threonine protein kinase
N24_RS00230	COG0768	penicillin binding
N24_RS00250	COG1716	ATPase activity
N24_RS00275	COG1053	succinate dehydrogenase
N24_RS00275	COG3976	FMN-binding domain protein
N24_RS00280	COG0477	Major facilitator Superfamily
N24_RS00290	COG1053	succinate dehydrogenase
N24_RS00300	COG1414	Transcriptional regulator
N24_RS00305	COG2409	Drug exporters of the RND superfamily
N24_RS00330	COG1126	abc transporter atp-binding protein
N24_RS00345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N24_RS00355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N24_RS00445	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N24_RS00455	COG2851	Citrate transporter
N24_RS00460	COG3290	protein histidine kinase activity
N24_RS00465	COG4565	transcriptional regulatory protein
N24_RS00470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N24_RS00480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N24_RS00525	COG0402	S-adenosylhomocysteine deaminase activity
N24_RS00540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N24_RS00545	COG0477	Major facilitator Superfamily
N24_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS00590	COG2610	gluconate transmembrane transporter activity
N24_RS00595	COG1846	Transcriptional regulator
N24_RS00630	COG0804	urea catabolic process
N24_RS00635	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
N24_RS00640	COG0830	nickel cation binding
N24_RS00645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N24_RS00650	COG0829	nickel cation binding
N24_RS00665	COG2814	Major facilitator Superfamily
N24_RS00675	COG0326	Molecular chaperone. Has ATPase activity
N24_RS00680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N24_RS00700	COG2132	Multicopper oxidase
N24_RS00710	COG0745	RESPONSE REGULATOR receiver
N24_RS00715	COG2205	protein histidine kinase activity
N24_RS00725	COG2217	Heavy metal translocating P-type atpase
N24_RS00730	COG1388	LysM domain
N24_RS00780	COG1401	restriction endodeoxyribonuclease activity
N24_RS00800	COG1012	belongs to the aldehyde dehydrogenase family
N24_RS00805	COG0667	Aldo Keto reductase
N24_RS00810	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N24_RS00825	COG1012	belongs to the aldehyde dehydrogenase family
N24_RS00830	COG0477	Major facilitator Superfamily
N24_RS00835	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N24_RS00845	COG0583	DNA-binding transcription factor activity
N24_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS00875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N24_RS00880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N24_RS00885	COG2814	Major facilitator Superfamily
N24_RS00900	COG2094	Belongs to the DNA glycosylase MPG family
N24_RS00910	COG0666	response to abiotic stimulus
N24_RS00920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N24_RS00955	COG1053	succinate dehydrogenase
N24_RS00955	COG3976	FMN-binding domain protein
N24_RS00995	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N24_RS01030	COG2149	membrane
N24_RS01050	COG0346	lactoylglutathione lyase activity
N24_RS01055	COG2062	phosphohistidine phosphatase, SixA
N24_RS01075	COG1070	Carbohydrate kinase
N24_RS01110	COG3177	Filamentation induced by cAMP protein fic
N24_RS01125	COG3311	Transcriptional regulator
N24_RS01130	COG1569	PIN domain
N24_RS01150	COG2094	Belongs to the DNA glycosylase MPG family
N24_RS01155	COG0657	acetylesterase activity
N24_RS01165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N24_RS01215	COG1349	DNA-binding transcription factor activity
N24_RS01220	COG0800	Aldolase
N24_RS01225	COG2271	Major facilitator Superfamily
N24_RS01245	COG2860	membrane
N24_RS01265	COG3180	Ammonia monooxygenase
N24_RS01275	COG0730	response to heat
N24_RS01290	COG1643	Atp-dependent helicase
N24_RS01310	COG2818	Glycosylase
N24_RS01315	COG1280	lysine exporter protein (LysE YggA)
N24_RS01345	COG0251	oxidation-reduction process
N24_RS01360	COG1120	ATPase activity
N24_RS01365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS01370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS01400	COG1132	(ABC) transporter
N24_RS01405	COG3590	peptidase
N24_RS01425	COG2188	Transcriptional regulator
N24_RS01430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N24_RS01445	COG3718	enzyme involved in inositol metabolism
N24_RS01450	COG3962	Belongs to the TPP enzyme family
N24_RS01465	COG1082	Xylose isomerase domain protein TIM barrel
N24_RS01475	COG0673	inositol 2-dehydrogenase activity
N24_RS01485	COG1609	Transcriptional regulator
N24_RS01490	COG0673	inositol 2-dehydrogenase activity
N24_RS01505	COG1278	Cold shock
N24_RS01545	COG2814	Major facilitator Superfamily
N24_RS01555	COG0070	glutamate synthase
N24_RS01555	COG0067	glutamate synthase
N24_RS01555	COG0069	glutamate synthase activity
N24_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS01585	COG0277	FAD linked oxidase domain protein
N24_RS01620	COG2258	MOSC domain
N24_RS01625	COG1216	Glycosyl transferase, family 2
N24_RS01650	COG0604	alcohol dehydrogenase
N24_RS01670	COG1115	amino acid carrier protein
N24_RS01690	COG0521	Mo-molybdopterin cofactor biosynthetic process
N24_RS01690	COG0315	cyclic pyranopterin monophosphate synthase activity
N24_RS01695	COG0315	cyclic pyranopterin monophosphate synthase activity
N24_RS01710	COG0725	ABC transporter, periplasmic molybdate-binding protein
N24_RS01720	COG3842	ATPase activity
N24_RS01725	COG1950	PFAM Membrane protein of
N24_RS01730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N24_RS01775	COG0477	Major facilitator Superfamily
N24_RS01780	COG1414	Transcriptional regulator
N24_RS01785	COG2239	Acts as a magnesium transporter
N24_RS01790	COG0471	metal ion transport
N24_RS01800	COG0287	Prephenate dehydrogenase
N24_RS01815	COG3237	CsbD-like
N24_RS01830	COG2409	Drug exporters of the RND superfamily
N24_RS01835	COG0343	queuine tRNA-ribosyltransferase activity
N24_RS01855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N24_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N24_RS01900	COG3442	glutamine amidotransferase
N24_RS01905	COG0189	ligase activity
N24_RS01905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N24_RS01920	COG0697	spore germination
N24_RS01925	COG0527	aspartate kinase activity
N24_RS01960	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N24_RS01980	COG0798	PFAM Bile acid sodium symporter
N24_RS01985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N24_RS02005	COG0651	ATP synthesis coupled electron transport
N24_RS02010	COG1006	Multisubunit Na H antiporter MnhC subunit
N24_RS02015	COG2111	Na H antiporter
N24_RS02015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N24_RS02040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N24_RS02070	COG0745	RESPONSE REGULATOR receiver
N24_RS02075	COG3850	Histidine kinase
N24_RS02075	COG5002	protein histidine kinase activity
N24_RS02105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N24_RS02120	COG0251	oxidation-reduction process
N24_RS02125	COG0477	Major facilitator Superfamily
N24_RS02135	COG1846	Transcriptional regulator
N24_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS02150	COG1960	acyl-CoA dehydrogenase activity
N24_RS02160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N24_RS02165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N24_RS02180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N24_RS02245	COG1111	helicase
N24_RS02245	COG1205	dead DEAH box helicase
N24_RS02250	COG1278	Cold shock
N24_RS02255	COG1754	DNA topoisomerase type I activity
N24_RS02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N24_RS02360	COG0737	Belongs to the 5'-nucleotidase family
N24_RS02360	COG4085	toxin activity
N24_RS02360	COG1525	nuclease
N24_RS02390	COG1064	alcohol dehydrogenase
N24_RS02405	COG1088	dTDP-glucose 4,6-dehydratase activity
N24_RS02410	COG0778	Nitroreductase
N24_RS02415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N24_RS02445	COG1505	serine-type exopeptidase activity
N24_RS02460	COG2186	Transcriptional regulator
N24_RS02470	COG2084	Dehydrogenase
N24_RS02475	COG2610	gluconate transmembrane transporter activity
N24_RS02480	COG3237	CsbD-like
N24_RS02510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N24_RS02520	COG1086	Polysaccharide biosynthesis protein
N24_RS02585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N24_RS02590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N24_RS02595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N24_RS02600	COG1396	sequence-specific DNA binding
N24_RS02600	COG3800	Transcriptional regulator
N24_RS02610	COG1053	succinate dehydrogenase
N24_RS02615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N24_RS02640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N24_RS02645	COG0601	transmembrane transport
N24_RS02655	COG0277	FAD linked oxidase domain protein
N24_RS02665	COG2733	membrane
N24_RS02680	COG1309	transcriptional regulator
N24_RS02695	COG0788	formyltetrahydrofolate deformylase activity
N24_RS02700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N24_RS02710	COG1937	Protein conserved in bacteria
N24_RS02730	COG4558	Periplasmic binding protein
N24_RS02735	COG4139	cobalamin transport
N24_RS02740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N24_RS02780	COG0318	PFAM AMP-dependent synthetase and ligase
N24_RS02795	COG5002	protein histidine kinase activity
N24_RS02800	COG0745	RESPONSE REGULATOR receiver
N24_RS02820	COG0577	efflux transmembrane transporter activity
N24_RS02855	COG2826	transposase and inactivated derivatives, IS30 family
N24_RS02870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N24_RS02890	COG0477	Major facilitator Superfamily
N24_RS02895	COG1082	Xylose isomerase domain protein TIM barrel
N24_RS02895	COG3185	4-Hydroxyphenylpyruvate dioxygenase
N24_RS02900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N24_RS02910	COG0222	ribosome binding
N24_RS02915	COG3842	ATPase activity
N24_RS02930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N24_RS02930	COG1648	precorrin-2 dehydrogenase activity
N24_RS02975	COG0406	alpha-ribazole phosphatase activity
N24_RS02985	COG0785	Cytochrome C biogenesis protein
N24_RS02995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N24_RS03000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N24_RS03065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N24_RS03070	COG0583	DNA-binding transcription factor activity
N24_RS03090	COG1309	transcriptional regulator
N24_RS03105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N24_RS03110	COG2154	pterin-4-alpha-carbinolamine dehydratase
N24_RS03115	COG3340	Belongs to the peptidase S51 family
N24_RS03120	COG4948	Mandelate Racemase Muconate Lactonizing
N24_RS03135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N24_RS03135	COG0438	transferase activity, transferring glycosyl groups
N24_RS03155	COG0142	geranyltranstransferase activity
N24_RS03165	COG2826	transposase and inactivated derivatives, IS30 family
N24_RS03190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N24_RS03240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N24_RS03255	COG0085	RNA polymerase activity
N24_RS03260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N24_RS03280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N24_RS03310	COG1132	(ABC) transporter
N24_RS03315	COG1132	(ABC) transporter
N24_RS03325	COG2375	cellular response to nickel ion
N24_RS03330	COG1120	ATPase activity
N24_RS03335	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS03340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS03450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N24_RS03475	COG3845	ABC transporter
N24_RS03510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N24_RS03520	COG1841	ribosomal large subunit assembly
N24_RS03560	COG0574	Belongs to the PEP-utilizing enzyme family
N24_RS03560	COG3848	Pyruvate phosphate dikinase
N24_RS03565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N24_RS03565	COG0574	Belongs to the PEP-utilizing enzyme family
N24_RS03575	COG1414	Transcriptional regulator
N24_RS03580	COG0201	protein transport
N24_RS03625	COG0203	ribosomal protein L17
N24_RS03630	COG0101	tRNA pseudouridine synthase activity
N24_RS03660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N24_RS03680	COG1404	Belongs to the peptidase S8 family
N24_RS03690	COG1674	ftsk spoiiie
N24_RS03760	COG2985	domain, Protein
N24_RS03760	COG0569	domain protein
N24_RS03775	COG0456	acetyltransferase
N24_RS03785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N24_RS03785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N24_RS03800	COG0459	protein refolding
N24_RS03830	COG0516	GMP reductase activity
N24_RS03840	COG0583	DNA-binding transcription factor activity
N24_RS03845	COG0519	Catalyzes the synthesis of GMP from XMP
N24_RS03845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N24_RS03865	COG2197	response regulator
N24_RS03890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N24_RS03930	COG2409	Drug exporters of the RND superfamily
N24_RS03950	COG0702	epimerase
N24_RS03955	COG0415	Belongs to the DNA photolyase family
N24_RS03970	COG0577	efflux transmembrane transporter activity
N24_RS03970	COG1136	(ABC) transporter
N24_RS03975	COG2011	ABC-type metal ion transport system permease component
N24_RS03980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N24_RS03985	COG1464	Belongs to the NlpA lipoprotein family
N24_RS03990	COG0587	DNA-directed DNA polymerase activity
N24_RS04015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N24_RS04030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N24_RS04055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N24_RS04060	COG2873	o-acetylhomoserine
N24_RS04065	COG1966	Carbon starvation protein
N24_RS04075	COG2079	MmgE PrpD family protein
N24_RS04080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N24_RS04085	COG0372	Belongs to the citrate synthase family
N24_RS04090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N24_RS04105	COG2838	Isocitrate dehydrogenase
N24_RS04115	COG1120	ATPase activity
N24_RS04120	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS04125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS04135	COG2814	Major facilitator Superfamily
N24_RS04145	COG2860	membrane
N24_RS04160	COG1120	ATPase activity
N24_RS04165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS04170	COG0180	Tryptophanyl-tRNA synthetase
N24_RS04175	COG1295	ribonuclease BN
N24_RS04185	COG1686	Belongs to the peptidase S11 family
N24_RS04195	COG1388	LysM domain
N24_RS04195	COG0791	NLP P60 protein
N24_RS04215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N24_RS04220	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
N24_RS04220	COG1473	amidohydrolase
N24_RS04230	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N24_RS04240	COG0523	cobalamin synthesis protein
N24_RS04245	COG0492	ferredoxin-NADP+ reductase activity
N24_RS04260	COG1396	sequence-specific DNA binding
N24_RS04260	COG3800	Transcriptional regulator
N24_RS04265	COG4770	biotin carboxylase activity
N24_RS04270	COG2897	thiosulfate sulfurtransferase activity
N24_RS04275	COG0189	ligase activity
N24_RS04305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N24_RS04310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N24_RS04315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N24_RS04315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N24_RS04420	COG3842	ATPase activity
N24_RS04435	COG1316	TRANSCRIPTIONal
N24_RS04475	COG1482	cell wall glycoprotein biosynthetic process
N24_RS04500	COG0745	RESPONSE REGULATOR receiver
N24_RS04505	COG5002	protein histidine kinase activity
N24_RS04510	COG5401	PFAM Sporulation and spore germination
N24_RS04520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N24_RS04525	COG0653	protein targeting
N24_RS04535	COG1011	Hydrolase
N24_RS04545	COG1162	GTPase activity
N24_RS04550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N24_RS04615	COG0210	DNA helicase
N24_RS04620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N24_RS04625	COG2816	NAD+ diphosphatase activity
N24_RS04650	COG3480	Lon protease (S16) C-terminal proteolytic domain
N24_RS04670	COG1615	UPF0182 protein
N24_RS04675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N24_RS04680	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N24_RS04705	COG0483	inositol monophosphate 1-phosphatase activity
N24_RS04710	COG0483	inositol monophosphate 1-phosphatase activity
N24_RS04720	COG2884	Cell division ATP-binding protein ftsE
N24_RS04725	COG2177	Part of the ABC transporter FtsEX involved in
N24_RS04735	COG3189	MarR family transcriptional regulator
N24_RS04750	COG1132	(ABC) transporter
N24_RS04750	COG2375	cellular response to nickel ion
N24_RS04755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N24_RS04815	COG1061	Type III restriction enzyme res subunit
N24_RS04830	COG1652	LysM domain
N24_RS04855	COG2252	PERMEase
N24_RS04860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N24_RS04880	COG0372	Belongs to the citrate synthase family
N24_RS04885	COG0545	Peptidyl-prolyl cis-trans isomerase
N24_RS04900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N24_RS04910	COG3757	hydrolase, family 25
N24_RS04915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N24_RS04915	COG2070	2-Nitropropane dioxygenase
N24_RS04920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N24_RS04960	COG0588	phosphoglycerate mutase activity
N24_RS04995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N24_RS05010	COG1218	3'(2'),5'-bisphosphate nucleotidase
N24_RS05015	COG1201	RNA secondary structure unwinding
N24_RS05020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N24_RS05025	COG3304	Inner membrane component domain
N24_RS05030	COG0586	Pfam SNARE associated Golgi protein
N24_RS05040	COG0166	Belongs to the GPI family
N24_RS05050	COG1605	Chorismate mutase
N24_RS05065	COG0577	efflux transmembrane transporter activity
N24_RS05065	COG1136	(ABC) transporter
N24_RS05075	COG0739	heme binding
N24_RS05090	COG0138	bifunctional purine biosynthesis protein purh
N24_RS05100	COG1309	transcriptional regulator
N24_RS05120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N24_RS05130	COG0659	secondary active sulfate transmembrane transporter activity
N24_RS05150	COG0745	RESPONSE REGULATOR receiver
N24_RS05160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N24_RS05175	COG1970	mechanosensitive ion channel activity
N24_RS05185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N24_RS05190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N24_RS05210	COG2807	transmembrane transport
N24_RS05230	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
N24_RS05240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N24_RS05255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
N24_RS05260	COG0084	hydrolase, TatD family'
N24_RS05265	COG3583	domain protein
N24_RS05270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N24_RS05280	COG0488	(ABC) transporter
N24_RS05305	COG2326	polyphosphate kinase activity
N24_RS05310	COG0561	phosphatase activity
N24_RS05340	COG2409	Drug exporters of the RND superfamily
N24_RS05345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N24_RS05365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N24_RS05385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N24_RS05395	COG0193	aminoacyl-tRNA hydrolase activity
N24_RS05415	COG0193	aminoacyl-tRNA hydrolase activity
N24_RS05435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N24_RS05440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N24_RS05450	COG2132	Multicopper oxidase
N24_RS05455	COG1131	(ABC) transporter
N24_RS05465	COG4585	Histidine kinase
N24_RS05470	COG2201	protein-glutamate methylesterase activity
N24_RS05485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N24_RS05505	COG1132	(ABC) transporter
N24_RS05510	COG1132	(ABC) transporter
N24_RS05515	COG0405	Gamma-glutamyltransferase
N24_RS05530	COG1309	transcriptional regulator
N24_RS05555	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N24_RS05560	COG0531	amino acid
N24_RS05570	COG3956	TIGRFAM MazG family protein
N24_RS05620	COG1733	regulation of RNA biosynthetic process
N24_RS05625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N24_RS05630	COG2814	Major facilitator Superfamily
N24_RS05640	COG2207	Transcriptional regulator
N24_RS05655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N24_RS05665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N24_RS05675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N24_RS05680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N24_RS05740	COG1914	H( )-stimulated, divalent metal cation uptake system
N24_RS05745	COG1802	Transcriptional regulator
N24_RS05755	COG0114	fumarate hydratase activity
N24_RS05800	COG1494	fructose-1,6-bisphosphatase
N24_RS05820	COG1570	exodeoxyribonuclease VII activity
N24_RS05835	COG0628	permease
N24_RS05845	COG0733	neurotransmitter:sodium symporter activity
N24_RS05850	COG0012	GTP binding
N24_RS05855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N24_RS05895	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
N24_RS05910	COG0494	nUDIX hydrolase
N24_RS05930	COG2814	Major facilitator Superfamily
N24_RS05940	COG4221	oxidoreductase activity
N24_RS05955	COG0656	L-ascorbic acid biosynthetic process
N24_RS06015	COG0488	(ABC) transporter
N24_RS06025	COG2824	Alkylphosphonate utilization operon protein PhnA
N24_RS06035	COG2814	Major facilitator Superfamily
N24_RS06040	COG1104	cysteine desulfurase activity
N24_RS06050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N24_RS06070	COG2315	Protein conserved in bacteria
N24_RS06075	COG0095	Lipoate-protein ligase
N24_RS06085	COG2814	Major facilitator Superfamily
N24_RS06095	COG4721	ABC-type cobalt transport system, permease component
N24_RS06100	COG1122	ATPase activity
N24_RS06105	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N24_RS06115	COG0387	Pfam Sodium calcium exchanger
N24_RS06130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N24_RS06135	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N24_RS06145	COG2354	Protein conserved in bacteria
N24_RS06150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N24_RS06160	COG0494	nUDIX hydrolase
N24_RS06180	COG3949	Membrane
N24_RS06195	COG1217	gtp-binding protein TYPA
N24_RS06200	COG0747	negative chemotaxis
N24_RS06235	COG2171	N-acyltransferase activity
N24_RS06240	COG1113	amino acid transport
N24_RS06250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N24_RS06260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N24_RS06265	COG0463	Glycosyl transferase, family 2
N24_RS06290	COG0297	glycogen (starch) synthase activity
N24_RS06295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N24_RS06300	COG4122	O-methyltransferase activity
N24_RS06305	COG1595	DNA-templated transcription, initiation
N24_RS06345	COG0508	dehydrogenase complex catalyzes the overall conversion of
N24_RS06345	COG0567	Dehydrogenase, E1 component
N24_RS06350	COG1132	(ABC) transporter
N24_RS06360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N24_RS06365	COG2272	Belongs to the type-B carboxylesterase lipase family
N24_RS06430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N24_RS06435	COG4988	ABC transporter
N24_RS06440	COG1294	oxidase, subunit
N24_RS06445	COG1271	oxidase subunit
N24_RS06490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N24_RS06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N24_RS06520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N24_RS06545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N24_RS06550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N24_RS06565	COG2031	fatty acid transporter
N24_RS06570	COG2353	YceI-like domain
N24_RS06575	COG1846	Transcriptional regulator
N24_RS06605	COG0019	diaminopimelate decarboxylase activity
N24_RS06610	COG0460	homoserine dehydrogenase
N24_RS06640	COG1140	nitrate reductase beta subunit
N24_RS06655	COG0315	cyclic pyranopterin monophosphate synthase activity
N24_RS06655	COG0521	Mo-molybdopterin cofactor biosynthetic process
N24_RS06660	COG1253	flavin adenine dinucleotide binding
N24_RS06665	COG1253	flavin adenine dinucleotide binding
N24_RS06680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N24_RS06695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N24_RS06725	COG0356	it plays a direct role in the translocation of protons across the membrane
N24_RS06730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N24_RS06745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N24_RS06750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N24_RS06760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N24_RS06770	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
N24_RS06795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N24_RS06800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N24_RS06805	COG1116	anion transmembrane transporter activity
N24_RS06810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N24_RS06815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N24_RS06820	COG0366	Alpha amylase catalytic
N24_RS06825	COG1119	ATPase activity
N24_RS06845	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N24_RS06850	COG1104	cysteine desulfurase activity
N24_RS06865	COG1396	sequence-specific DNA binding
N24_RS06925	COG0154	amidase activity
N24_RS06940	COG0205	6-phosphofructokinase activity
N24_RS06945	COG1609	Transcriptional regulator
N24_RS06950	COG1129	ABC transporter
N24_RS06955	COG1172	Belongs to the binding-protein-dependent transport system permease family
N24_RS06960	COG1879	ABC-type sugar transport system periplasmic component
N24_RS06975	COG4607	ABC-type enterochelin transport system periplasmic component
N24_RS06980	COG0385	Bile acid
N24_RS07000	COG0667	Aldo Keto reductase
N24_RS07005	COG1279	arginine transmembrane transporter activity
N24_RS07010	COG0583	DNA-binding transcription factor activity
N24_RS07015	COG0435	Glutathione S-transferase
N24_RS07030	COG0129	dihydroxy-acid dehydratase activity
N24_RS07040	COG0668	transmembrane transport
N24_RS07045	COG0028	Belongs to the TPP enzyme family
N24_RS07050	COG0440	acetolactate synthase activity
N24_RS07085	COG0473	3-isopropylmalate dehydrogenase activity
N24_RS07105	COG0179	Fumarylacetoacetate (FAA) hydrolase
N24_RS07110	COG4106	trans-aconitate 2-methyltransferase activity
N24_RS07175	COG4115	mRNA cleavage
N24_RS07220	COG0406	alpha-ribazole phosphatase activity
N24_RS07220	COG0494	nUDIX hydrolase
N24_RS07240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N24_RS07245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N24_RS07250	COG1461	Dihydroxyacetone kinase
N24_RS07255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N24_RS07265	COG0742	ribosomal rna small subunit methyltransferase
N24_RS07280	COG2826	transposase and inactivated derivatives, IS30 family
N24_RS07285	COG1126	abc transporter atp-binding protein
N24_RS07295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N24_RS07330	COG2226	methyltransferase
N24_RS07340	COG0539	negative regulation of cytoplasmic translation
N24_RS07350	COG0237	dephospho-CoA kinase activity
N24_RS07370	COG0477	Major facilitator Superfamily
N24_RS07380	COG1609	Transcriptional regulator
N24_RS07405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N24_RS07425	COG1733	regulation of RNA biosynthetic process
N24_RS07430	COG0702	epimerase
N24_RS07435	COG3973	AAA domain
N24_RS07445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N24_RS07480	COG1175	transmembrane transport
N24_RS07485	COG0395	ABC-type sugar transport system, permease component
N24_RS07495	COG3842	ATPase activity
N24_RS07505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N24_RS07510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N24_RS07515	COG0072	phenylalanine-tRNA ligase activity
N24_RS07515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N24_RS07545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N24_RS07560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N24_RS07565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N24_RS07575	COG0137	argininosuccinate synthase activity
N24_RS07580	COG0165	Argininosuccinate lyase
N24_RS07600	COG2835	tetraacyldisaccharide 4'-kinase activity
N24_RS07605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N24_RS07615	COG2814	Major facilitator Superfamily
N24_RS07645	COG0647	UMP catabolic process
N24_RS07660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N24_RS07690	COG0494	nUDIX hydrolase
N24_RS07695	COG4974	Belongs to the 'phage' integrase family
N24_RS07715	COG2897	thiosulfate sulfurtransferase activity
N24_RS07720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N24_RS07730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N24_RS07735	COG1160	GTP binding
N24_RS07750	COG1132	(ABC) transporter
N24_RS07755	COG1132	(ABC) transporter
N24_RS07760	COG0428	transporter
N24_RS07765	COG0025	NhaP-type Na H and K H
N24_RS07785	COG3012	SEC-C Motif Domain Protein
N24_RS07795	COG0653	protein targeting
N24_RS07800	COG1716	ATPase activity
N24_RS07835	COG1253	flavin adenine dinucleotide binding
N24_RS07840	COG1253	flavin adenine dinucleotide binding
N24_RS07845	COG0513	Belongs to the DEAD box helicase family
N24_RS07850	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N24_RS07870	COG0842	Transport permease protein
N24_RS07880	COG3639	organic phosphonate transmembrane transporter activity
N24_RS07885	COG3639	organic phosphonate transmembrane transporter activity
N24_RS07890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
N24_RS07905	COG0351	phosphomethylpyrimidine kinase
N24_RS07905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N24_RS07905	COG0352	thiamine-phosphate diphosphorylase activity
N24_RS07915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N24_RS07925	COG0477	Major facilitator Superfamily
N24_RS07930	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
N24_RS07955	COG0659	secondary active sulfate transmembrane transporter activity
N24_RS07985	COG0463	Glycosyl transferase, family 2
N24_RS08015	COG0300	oxidoreductase activity
N24_RS08030	COG4581	dead DEAH box helicase
N24_RS08035	COG0805	protein transport
N24_RS08040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N24_RS08045	COG2378	regulation of single-species biofilm formation
N24_RS08080	COG1362	aminopeptidase activity
N24_RS08095	COG2814	Major facilitator Superfamily
N24_RS08100	COG1027	Aspartate ammonia-lyase
N24_RS08115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N24_RS08120	COG1410	methionine synthase
N24_RS08120	COG0646	methionine synthase
N24_RS08130	COG2072	flavoprotein involved in K transport
N24_RS08140	COG0798	PFAM Bile acid sodium symporter
N24_RS08145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N24_RS08150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N24_RS08165	COG1968	undecaprenyl-diphosphatase activity
N24_RS08170	COG0667	Aldo Keto reductase
N24_RS08180	COG0167	dihydroorotate dehydrogenase activity
N24_RS08185	COG2197	response regulator
N24_RS08210	COG1881	PFAM PEBP family protein
N24_RS08215	COG1132	(ABC) transporter
N24_RS08220	COG1132	(ABC) transporter
N24_RS08240	COG0398	Pfam SNARE associated Golgi protein
N24_RS08270	COG2826	transposase and inactivated derivatives, IS30 family
N24_RS08275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N24_RS08280	COG3883	PFAM NLP P60 protein
N24_RS08280	COG0791	NLP P60 protein
N24_RS08290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N24_RS08295	COG1309	transcriptional regulator
N24_RS08315	COG3830	Belongs to the UPF0237 family
N24_RS08320	COG2848	UPF0210 protein
N24_RS08325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N24_RS08345	COG0488	(ABC) transporter
N24_RS08355	COG2151	metal-sulfur cluster biosynthetic enzyme
N24_RS08360	COG0822	iron-sulfur transferase activity
N24_RS08370	COG0396	ATPase activity
N24_RS08425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N24_RS08430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N24_RS08455	COG2423	ornithine cyclodeaminase activity
N24_RS08460	COG0004	ammonium transporteR
N24_RS08465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N24_RS08485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N24_RS08495	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N24_RS08505	COG0322	excinuclease ABC activity
N24_RS08550	COG0242	peptide deformylase activity
N24_RS08555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N24_RS08560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N24_RS08575	COG1758	RNA polymerase activity
N24_RS08580	COG0194	GDP metabolic process
N24_RS08595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N24_RS08600	COG0505	Belongs to the CarA family
N24_RS08605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N24_RS08660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N24_RS08670	COG0006	proline dipeptidase activity
N24_RS08680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N24_RS08685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N24_RS08700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS08710	COG1120	ATPase activity
N24_RS08720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N24_RS08725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N24_RS08760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N24_RS08770	COG1129	ABC transporter
N24_RS08785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N24_RS08795	COG1760	l-serine dehydratase
N24_RS08800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N24_RS08805	COG0124	histidyl-tRNA synthetase
N24_RS08815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N24_RS08830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N24_RS08835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N24_RS08845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N24_RS08850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N24_RS08865	COG0632	four-way junction helicase activity
N24_RS08870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N24_RS08880	COG1946	Acyl-CoA thioesterase
N24_RS08895	COG0438	transferase activity, transferring glycosyl groups
N24_RS08900	COG1560	Kdo2-lipid A biosynthetic process
N24_RS08905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N24_RS08915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N24_RS09265	COG2453	phosphatase
N24_RS09265	COG0671	phosphoesterase, PA-phosphatase related
N24_RS09285	COG2186	Transcriptional regulator
N24_RS09310	COG3177	Filamentation induced by cAMP protein fic
N24_RS09550	COG0542	response to heat
N24_RS09895	COG0471	metal ion transport
N24_RS09900	COG0583	DNA-binding transcription factor activity
N24_RS09910	COG1929	Belongs to the glycerate kinase type-1 family
N24_RS09935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N24_RS09950	COG3253	May function as heme-dependent peroxidase
N24_RS09960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N24_RS09980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N24_RS09985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N24_RS10015	COG0483	inositol monophosphate 1-phosphatase activity
N24_RS10030	COG2311	Membrane
N24_RS10040	COG1061	Type III restriction enzyme res subunit
N24_RS10070	COG1321	iron dependent repressor
N24_RS10075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N24_RS10095	COG0583	DNA-binding transcription factor activity
N24_RS10105	COG1643	Atp-dependent helicase
N24_RS10125	COG1349	DNA-binding transcription factor activity
N24_RS10135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N24_RS10140	COG1349	DNA-binding transcription factor activity
N24_RS10145	COG1105	Belongs to the carbohydrate kinase PfkB family
N24_RS10150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N24_RS10150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N24_RS10150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N24_RS10165	COG2233	PERMEase
N24_RS10170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N24_RS10185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N24_RS10200	COG1196	nuclear chromosome segregation
N24_RS10230	COG1126	abc transporter atp-binding protein
N24_RS10235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N24_RS10240	COG0765	amino acid transport
N24_RS10245	COG0765	amino acid transport
N24_RS10250	COG2137	regulation of response to DNA damage stimulus
N24_RS10265	COG1268	BioY protein
N24_RS10270	COG1122	ATPase activity
N24_RS10280	COG1842	Phage shock protein A
N24_RS10285	COG1396	sequence-specific DNA binding
N24_RS10310	COG1674	ftsk spoiiie
N24_RS10320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N24_RS10325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N24_RS10330	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
N24_RS10335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N24_RS10345	COG1185	polyribonucleotide nucleotidyltransferase activity
N24_RS10375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N24_RS10385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N24_RS10410	COG0779	Required for maturation of 30S ribosomal subunits
N24_RS10420	COG4166	transmembrane transport
N24_RS10425	COG0601	transmembrane transport
N24_RS10430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N24_RS10435	COG4172	Belongs to the ABC transporter superfamily
N24_RS10445	COG3022	response to hydroperoxide
N24_RS10460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N24_RS10460	COG1648	precorrin-2 dehydrogenase activity
N24_RS10465	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N24_RS10515	COG2197	response regulator
N24_RS10520	COG3850	Histidine kinase
N24_RS10525	COG0577	efflux transmembrane transporter activity
N24_RS10530	COG1136	(ABC) transporter
N24_RS10535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N24_RS10540	COG0750	zinc metalloprotease
N24_RS10560	COG4555	ABC transporter
N24_RS10590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N24_RS10605	COG4974	Belongs to the 'phage' integrase family
N24_RS10620	COG0792	nuclease activity
N24_RS10630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N24_RS10635	COG0681	Belongs to the peptidase S26 family
N24_RS10655	COG0352	thiamine-phosphate diphosphorylase activity
N24_RS10660	COG2022	thiamine diphosphate biosynthetic process
N24_RS10660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N24_RS10670	COG2022	thiamine diphosphate biosynthetic process
N24_RS10675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N24_RS10685	COG1609	Transcriptional regulator
N24_RS10690	COG0471	metal ion transport
N24_RS10710	COG0336	Belongs to the RNA methyltransferase TrmD family
N24_RS10720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N24_RS10755	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N24_RS10785	COG1196	nuclear chromosome segregation
N24_RS10790	COG1254	Belongs to the acylphosphatase family
N24_RS10815	COG0604	alcohol dehydrogenase
N24_RS10840	COG0571	ribonuclease III activity
N24_RS10855	COG5265	(ABC) transporter
N24_RS10860	COG1132	(ABC) transporter
N24_RS10865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N24_RS10870	COG1929	Belongs to the glycerate kinase type-1 family
N24_RS10890	COG0058	SHG alpha-glucan phosphorylase activity
N24_RS10895	COG2514	catechol 2,3-dioxygenase activity
N24_RS10900	COG0469	pyruvate kinase activity
N24_RS10910	COG0134	indole-3-glycerol-phosphate synthase activity
N24_RS10930	COG0483	inositol monophosphate 1-phosphatase activity
N24_RS10935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N24_RS10940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N24_RS10965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N24_RS10995	COG2226	methyltransferase
N24_RS11005	COG0673	inositol 2-dehydrogenase activity
N24_RS11010	COG1609	Transcriptional regulator
N24_RS11015	COG2375	cellular response to nickel ion
N24_RS11015	COG1132	(ABC) transporter
N24_RS11065	COG1739	Uncharacterized protein family UPF0029
N24_RS11075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N24_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS11115	COG0019	diaminopimelate decarboxylase activity
N24_RS11135	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N24_RS11145	COG0488	(ABC) transporter
N24_RS11155	COG0252	asparaginase activity
N24_RS11180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N24_RS11190	COG3599	regulation of cell shape
N24_RS11200	COG1799	cell septum assembly
N24_RS11205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N24_RS11210	COG1496	oxidoreductase activity
N24_RS11215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N24_RS11220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N24_RS11230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N24_RS11240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N24_RS11245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N24_RS11255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N24_RS11260	COG0768	penicillin binding
N24_RS11270	COG0275	rRNA processing
N24_RS11290	COG0456	acetyltransferase
N24_RS11300	COG0142	geranyltranstransferase activity
N24_RS11315	COG0515	serine threonine protein kinase
N24_RS11315	COG2815	serine threonine protein kinase
N24_RS11320	COG5650	phosphatidylinositol metabolic process
N24_RS11325	COG5650	phosphatidylinositol metabolic process
N24_RS11330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
N24_RS11360	COG1940	carbohydrate kinase activity
N24_RS11365	COG0438	transferase activity, transferring glycosyl groups
N24_RS11370	COG0791	NLP P60 protein
N24_RS11380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N24_RS11385	COG0723	plastoquinol--plastocyanin reductase activity
N24_RS11390	COG2010	Cytochrome c
N24_RS11395	COG1845	cytochrome c oxidase, subunit III
N24_RS11410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N24_RS11445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N24_RS11450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N24_RS11460	COG0508	dehydrogenase complex catalyzes the overall conversion of
N24_RS11480	COG2985	domain, Protein
N24_RS11480	COG0569	domain protein
N24_RS11495	COG0174	glutamine synthetase
N24_RS11515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N24_RS11520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N24_RS11550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N24_RS11555	COG0174	glutamine synthetase
N24_RS11580	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
N24_RS11600	COG3323	Protein of unknown function (DUF1653)
N24_RS11600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N24_RS11625	COG1280	lysine exporter protein (LysE YggA)
N24_RS11645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
N24_RS11670	COG0596	Alpha beta hydrolase
N24_RS11675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N24_RS11760	COG3387	PFAM Glycoside hydrolase 15-related
N24_RS11770	COG0358	DNA primase activity
N24_RS11785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N24_RS11790	COG0246	Mannitol dehydrogenase
N24_RS11795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N24_RS11795	COG2213	PTS system mannitol-specific
N24_RS11800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N24_RS11825	COG0423	glycine-tRNA ligase activity
N24_RS11850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N24_RS11860	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N24_RS11885	COG0484	heat shock protein binding
N24_RS11925	COG1132	(ABC) transporter
N24_RS11940	COG0339	signal peptide processing
N24_RS11950	COG0366	Alpha amylase catalytic
N24_RS11955	COG3281	Trehalose synthase
N24_RS11985	COG1114	Component of the transport system for branched-chain amino acids
N24_RS11990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N24_RS11995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N24_RS12010	COG0747	negative chemotaxis
N24_RS12015	COG0601	transmembrane transport
N24_RS12020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N24_RS12025	COG4172	Belongs to the ABC transporter superfamily
N24_RS12030	COG0300	oxidoreductase activity
N24_RS12035	COG0583	DNA-binding transcription factor activity
N24_RS12040	COG2851	Citrate transporter
N24_RS12060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N24_RS12075	COG0676	glucose-6-phosphate 1-epimerase activity
N24_RS12080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N24_RS12085	COG2224	Isocitrate lyase
N24_RS12100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N24_RS12105	COG2826	transposase and inactivated derivatives, IS30 family
N24_RS12140	COG1058	Belongs to the CinA family
N24_RS12140	COG1546	Belongs to the CinA family
N24_RS12160	COG2801	Transposase and inactivated derivatives
N24_RS12175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N24_RS12185	COG0481	GTPase activity
N24_RS12200	COG1280	lysine exporter protein (LysE YggA)
N24_RS12225	COG1307	EDD domain protein, DegV family
N24_RS12230	COG0406	alpha-ribazole phosphatase activity
N24_RS12240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N24_RS12260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N24_RS12295	COG1530	ribonuclease E activity
N24_RS12335	COG0285	dihydrofolate synthase activity
N24_RS12340	COG0525	valine-tRNA ligase activity
N24_RS12345	COG4166	transmembrane transport
N24_RS12350	COG0443	Heat shock 70 kDa protein
N24_RS12360	COG0039	L-malate dehydrogenase activity
N24_RS12365	COG1309	transcriptional regulator
N24_RS12380	COG0633	Ferredoxin
N24_RS12380	COG0543	2 iron, 2 sulfur cluster binding
N24_RS12385	COG2814	Major facilitator Superfamily
N24_RS12415	COG1414	Transcriptional regulator
N24_RS12420	COG0183	Belongs to the thiolase family
N24_RS12425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N24_RS12435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N24_RS12440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N24_RS12445	COG3485	protocatechuate 3,4-dioxygenase
N24_RS12450	COG3485	protocatechuate 3,4-dioxygenase
N24_RS12460	COG4829	muconolactone delta-isomerase
N24_RS12465	COG4948	Mandelate Racemase Muconate Lactonizing
N24_RS12470	COG3485	protocatechuate 3,4-dioxygenase
N24_RS12475	COG4638	Rieske (2fe-2S)
N24_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS12500	COG2814	Major facilitator Superfamily
N24_RS12515	COG1960	acyl-CoA dehydrogenase activity
N24_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS12540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N24_RS12555	COG0154	amidase activity
N24_RS12590	COG0740	serine-type endopeptidase activity
N24_RS12595	COG0740	serine-type endopeptidase activity
N24_RS12630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N24_RS12695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N24_RS12705	COG0747	negative chemotaxis
N24_RS12715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N24_RS12730	COG4221	oxidoreductase activity
N24_RS12745	COG1119	ATPase activity
N24_RS12750	COG0668	transmembrane transport
N24_RS12790	COG1785	Belongs to the alkaline phosphatase family
N24_RS12820	COG1396	sequence-specific DNA binding
N24_RS12835	COG1606	tRNA processing
N24_RS12840	COG1691	(AIR) carboxylase
N24_RS12850	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
N24_RS12855	COG3622	Belongs to the hyi family
N24_RS12860	COG4221	oxidoreductase activity
N24_RS12875	COG1376	ErfK ybiS ycfS ynhG family protein
N24_RS12890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N24_RS12910	COG2066	Belongs to the glutaminase family
N24_RS12915	COG1609	Transcriptional regulator
N24_RS12920	COG1904	glucuronate isomerase
N24_RS12925	COG0246	Mannitol dehydrogenase
N24_RS12935	COG3265	gluconokinase activity
N24_RS12945	COG1335	isochorismatase
N24_RS12970	COG2814	Major facilitator Superfamily
N24_RS12995	COG3835	regulator
N24_RS13010	COG4585	Histidine kinase
N24_RS13015	COG2197	response regulator
N24_RS13025	COG1566	PFAM secretion protein HlyD family protein
N24_RS13035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N24_RS13055	COG1234	tRNA 3'-trailer cleavage
N24_RS13060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N24_RS13070	COG1846	Transcriptional regulator
N24_RS13080	COG3191	aminopeptidase activity
N24_RS13100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N24_RS13125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N24_RS13155	COG2186	Transcriptional regulator
N24_RS13170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N24_RS13180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N24_RS13190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N24_RS13200	COG0604	alcohol dehydrogenase
N24_RS13205	COG2079	MmgE PrpD family protein
N24_RS13230	COG0033	Phosphoglucomutase
N24_RS13235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N24_RS13240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N24_RS13255	COG1823	symporter activity
N24_RS13260	COG0577	efflux transmembrane transporter activity
N24_RS13260	COG1136	(ABC) transporter
N24_RS13265	COG1136	(ABC) transporter
N24_RS13275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N24_RS13275	COG1042	CoA-binding domain protein
N24_RS13275	COG0045	succinate-CoA ligase (ADP-forming) activity
N24_RS13290	COG2814	Major facilitator Superfamily
N24_RS13330	COG0673	inositol 2-dehydrogenase activity
N24_RS13345	COG2211	Major facilitator Superfamily
N24_RS13375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N24_RS13385	COG2197	response regulator
N24_RS13400	COG1045	serine acetyltransferase
N24_RS13425	COG0045	succinate-CoA ligase (ADP-forming) activity
N24_RS13440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N24_RS13495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N24_RS13500	COG0581	inorganic phosphate transmembrane transporter activity
N24_RS13515	COG0456	acetyltransferase
N24_RS13525	COG1597	lipid kinase activity
N24_RS13555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N24_RS13590	COG0047	phosphoribosylformylglycinamidine synthase activity
N24_RS13595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N24_RS13600	COG0386	Belongs to the glutathione peroxidase family
N24_RS13625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N24_RS13630	COG0436	Aminotransferase
N24_RS13635	COG0151	Belongs to the GarS family
N24_RS13640	COG0537	adenosine 5'-monophosphoramidase activity
N24_RS13650	COG2205	protein histidine kinase activity
N24_RS13655	COG0745	RESPONSE REGULATOR receiver
N24_RS13660	COG0789	Transcriptional regulator
N24_RS13670	COG0028	Belongs to the TPP enzyme family
N24_RS13680	COG1309	transcriptional regulator
N24_RS13695	COG1053	succinate dehydrogenase
N24_RS13700	COG1053	succinate dehydrogenase
N24_RS13705	COG1063	alcohol dehydrogenase
N24_RS13715	COG0477	Major facilitator Superfamily
N24_RS13720	COG0583	DNA-binding transcription factor activity
N24_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS13735	COG1748	Saccharopine dehydrogenase
N24_RS13775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N24_RS13790	COG1609	Transcriptional regulator
N24_RS13800	COG1121	(ABC) transporter
N24_RS13805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N24_RS13810	COG1053	succinate dehydrogenase
N24_RS13820	COG0673	inositol 2-dehydrogenase activity
N24_RS13825	COG0477	Major facilitator Superfamily
N24_RS13845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N24_RS13860	COG1621	beta-fructofuranosidase activity
N24_RS13870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N24_RS13875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N24_RS13900	COG4166	transmembrane transport
N24_RS13910	COG0444	Belongs to the ABC transporter superfamily
N24_RS13915	COG4608	Belongs to the ABC transporter superfamily
N24_RS13925	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N24_RS13930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N24_RS13940	COG0745	RESPONSE REGULATOR receiver
N24_RS13945	COG2205	protein histidine kinase activity
N24_RS13950	COG2847	Copper chaperone PCu(A)C
N24_RS13960	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N24_RS13980	COG1194	a g-specific adenine glycosylase
N24_RS14005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N24_RS14015	COG0542	response to heat
N24_RS14025	COG2207	Transcriptional regulator
N24_RS14045	COG2814	Major facilitator Superfamily
N24_RS14060	COG2814	Major facilitator Superfamily
N24_RS14070	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N24_RS14075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N24_RS14095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N24_RS14110	COG0302	gtp cyclohydrolase
N24_RS14115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N24_RS14125	COG0037	tRNA processing
N24_RS14130	COG2027	D-alanyl-D-alanine carboxypeptidase
N24_RS14135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N24_RS14140	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N24_RS14145	COG3766	membrane
N24_RS14165	COG3711	transcriptional antiterminator
N24_RS14170	COG2723	6-phospho-beta-galactosidase activity
N24_RS14195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N24_RS14200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS14205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS14210	COG1120	ATPase activity
N24_RS14215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N24_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
N24_RS14255	COG2326	polyphosphate kinase activity
N24_RS14270	COG1100	Small GTP-binding protein
N24_RS14320	COG2111	Na H antiporter
N24_RS14320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N24_RS14325	COG1006	Multisubunit Na H antiporter MnhC subunit
N24_RS14330	COG0651	ATP synthesis coupled electron transport
N24_RS14340	COG2212	antiporter activity
N24_RS14375	COG0242	peptide deformylase activity
N24_RS14390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N24_RS14400	COG2814	Major facilitator Superfamily
N24_RS14420	COG1131	(ABC) transporter
N24_RS14440	COG0515	serine threonine protein kinase
N24_RS14450	COG0280	phosphate acetyltransferase
N24_RS14490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N24_RS14505	COG4129	membrane
N24_RS14510	COG0191	fructose-bisphosphate aldolase activity
N24_RS14525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N24_RS14555	COG0542	response to heat
N24_RS14565	COG0492	ferredoxin-NADP+ reductase activity
N24_RS14615	COG1012	belongs to the aldehyde dehydrogenase family
N24_RS14620	COG0789	Transcriptional regulator
N24_RS14625	COG0484	heat shock protein binding
N24_RS14630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N24_RS14675	COG2382	esterase
N24_RS14680	COG4592	Periplasmic binding protein
N24_RS14690	COG0667	Aldo Keto reductase
N24_RS14715	COG0730	response to heat
N24_RS14745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N24_RS14800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N24_RS14810	COG3842	ATPase activity
N24_RS14850	COG2818	Glycosylase
N24_RS14855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N24_RS14855	COG1017	nitric oxide dioxygenase activity
N24_RS14865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N24_RS14870	COG3711	transcriptional antiterminator
N24_RS14880	COG1263	PTS System
N24_RS14880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N24_RS14880	COG2190	(PTS) system
N24_RS14885	COG4592	Periplasmic binding protein
N24_RS14890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS14895	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N24_RS14900	COG1120	ATPase activity
N24_RS14915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N24_RS14940	COG1472	Belongs to the glycosyl hydrolase 3 family
N24_RS14955	COG4981	capsule polysaccharide biosynthetic process
N24_RS14985	COG0438	transferase activity, transferring glycosyl groups
N24_RS15040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N24_RS15045	COG3321	synthase
N24_RS15045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N24_RS15045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N24_RS15050	COG0318	PFAM AMP-dependent synthetase and ligase
N24_RS15055	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
N24_RS15065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N24_RS15065	COG5479	isomerase activity
N24_RS15070	COG2610	gluconate transmembrane transporter activity
N24_RS15085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N24_RS15090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N24_RS15095	COG0671	phosphoesterase, PA-phosphatase related
N24_RS15100	COG1216	Glycosyl transferase, family 2
N24_RS15110	COG0671	phosphoesterase, PA-phosphatase related
N24_RS15140	COG0561	phosphatase activity
N24_RS15150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N24_RS15155	COG2188	Transcriptional regulator
N24_RS15180	COG0077	Prephenate dehydratase
N24_RS15185	COG0154	amidase activity
N24_RS15225	COG1316	TRANSCRIPTIONal
N24_RS15250	COG2610	gluconate transmembrane transporter activity
N24_RS15260	COG2186	Transcriptional regulator
N24_RS15270	COG1027	Aspartate ammonia-lyase
N24_RS15280	COG0469	pyruvate kinase activity
N24_RS15305	COG2188	Transcriptional regulator
N24_RS15310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N24_RS15315	COG0477	Major facilitator Superfamily
N24_RS15330	COG3093	addiction module antidote protein HigA
N24_RS15355	COG0583	DNA-binding transcription factor activity
N24_RS15360	COG2814	Major facilitator Superfamily
N24_RS15380	COG2197	response regulator
N24_RS15385	COG3850	Histidine kinase
N24_RS15400	COG3764	Sortase (surface protein transpeptidase)
N24_RS15430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N24_RS15480	COG1842	Phage shock protein A
N24_RS15485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N24_RS15495	COG0477	Major facilitator Superfamily
N24_RS15505	COG1695	Transcriptional regulator
N24_RS15510	COG0305	Participates in initiation and elongation during chromosome replication
N24_RS15520	COG0629	single-stranded DNA binding
N24_RS15525	COG0360	Binds together with S18 to 16S ribosomal RNA
N24_RS15540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N24_RS15550	COG1846	Transcriptional regulator
N24_RS15570	COG1054	Belongs to the UPF0176 family
N24_RS15580	COG1136	(ABC) transporter
N24_RS15590	COG1260	myo-inositol-1-phosphate synthase
N24_RS15605	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS15610	COG3959	Transketolase, thiamine diphosphate binding domain
N24_RS15615	COG3958	Transketolase
N24_RS15630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N24_RS15630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N24_RS15630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N24_RS15635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N24_RS15645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N24_RS15650	COG4868	Belongs to the UPF0371 family
N24_RS15655	COG0783	Belongs to the Dps family
N24_RS15660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N24_RS15665	COG1690	Belongs to the RtcB family
N24_RS15675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N24_RS15730	COG0778	Nitroreductase
N24_RS15745	COG2832	Protein of unknown function (DUF454)
N24_RS15760	COG0179	Fumarylacetoacetate (FAA) hydrolase
N24_RS15770	COG1414	Transcriptional regulator
N24_RS15775	COG2814	Major facilitator Superfamily
N24_RS15780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N24_RS15785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N24_RS15805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N24_RS15810	COG0512	Glutamine amidotransferase of anthranilate synthase
N24_RS15820	COG0135	phosphoribosylanthranilate isomerase activity
N24_RS15820	COG0134	indole-3-glycerol-phosphate synthase activity
N24_RS15825	COG0133	tryptophan synthase activity
N24_RS15830	COG0159	tryptophan synthase activity
N24_RS15835	COG1131	(ABC) transporter
N24_RS15870	COG1902	pentaerythritol trinitrate reductase activity
N24_RS15890	COG3104	oligopeptide transport
N24_RS15895	COG1309	transcriptional regulator
N24_RS15910	COG2814	Major facilitator Superfamily
N24_RS15915	COG1414	Transcriptional regulator
N24_RS15920	COG0673	inositol 2-dehydrogenase activity
N24_RS15930	COG0673	inositol 2-dehydrogenase activity
N24_RS15935	COG0673	inositol 2-dehydrogenase activity
N24_RS15940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N24_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
N24_RS15955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N24_RS15960	COG2271	Major facilitator Superfamily
N24_RS15965	COG1414	Transcriptional regulator
N24_RS15975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N24_RS15980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N24_RS15985	COG1802	Transcriptional regulator
N24_RS16005	COG0477	Major facilitator Superfamily
N24_RS16065	COG0351	phosphomethylpyrimidine kinase
N24_RS16075	COG2608	mercury ion transmembrane transporter activity
N24_RS16080	COG1687	branched-chain amino acid
N24_RS16085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N24_RS16090	COG1678	Uncharacterized ACR, COG1678
N24_RS16095	COG0617	tRNA 3'-terminal CCA addition
N24_RS16125	COG3118	belongs to the thioredoxin family
N24_RS16130	COG0860	N-Acetylmuramoyl-L-alanine amidase
N24_RS16130	COG3409	Peptidoglycan-binding domain 1 protein
N24_RS16145	COG1192	Involved in chromosome partitioning
N24_RS16160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N24_RS16165	COG0594	ribonuclease P activity