locus-tag	class	description
CIMIT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIMIT_RS00010	COG0592	DNA-directed DNA polymerase activity
CIMIT_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIMIT_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CIMIT_RS00025	COG0187	DNA topoisomerase II activity
CIMIT_RS00055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIMIT_RS00090	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CIMIT_RS00130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CIMIT_RS00150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIMIT_RS00170	COG2815	serine threonine protein kinase
CIMIT_RS00170	COG0515	serine threonine protein kinase
CIMIT_RS00175	COG0515	serine threonine protein kinase
CIMIT_RS00180	COG0768	penicillin binding
CIMIT_RS00200	COG1716	ATPase activity
CIMIT_RS00200	COG1716	ATPase activity
CIMIT_RS00230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIMIT_RS00235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CIMIT_RS00250	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CIMIT_RS00250	COG3266	domain, Protein
CIMIT_RS00250	COG4932	domain protein
CIMIT_RS00260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CIMIT_RS00270	COG1104	cysteine desulfurase activity
CIMIT_RS00275	COG1619	proteins homologs of microcin C7 resistance protein MccF
CIMIT_RS00280	COG0477	Major facilitator Superfamily
CIMIT_RS00325	COG1476	TRANSCRIPTIONal
CIMIT_RS00330	COG2066	Belongs to the glutaminase family
CIMIT_RS00350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CIMIT_RS00375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIMIT_RS00380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CIMIT_RS00385	COG1301	dicarboxylic acid transport
CIMIT_RS00405	COG3180	Ammonia monooxygenase
CIMIT_RS00420	COG0531	amino acid
CIMIT_RS00425	COG1643	Atp-dependent helicase
CIMIT_RS00445	COG1280	lysine exporter protein (LysE YggA)
CIMIT_RS00460	COG2501	S4 domain
CIMIT_RS00475	COG3590	peptidase
CIMIT_RS00495	COG2197	response regulator
CIMIT_RS00505	COG1136	(ABC) transporter
CIMIT_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
CIMIT_RS00520	COG0277	FAD linked oxidase domain protein
CIMIT_RS00540	COG1216	Glycosyl transferase, family 2
CIMIT_RS00615	COG0287	Prephenate dehydrogenase
CIMIT_RS00625	COG0590	tRNA wobble adenosine to inosine editing
CIMIT_RS00625	COG0037	tRNA processing
CIMIT_RS00640	COG2409	Drug exporters of the RND superfamily
CIMIT_RS00645	COG0343	queuine tRNA-ribosyltransferase activity
CIMIT_RS00655	COG0577	efflux transmembrane transporter activity
CIMIT_RS00655	COG1136	(ABC) transporter
CIMIT_RS00660	COG2801	Transposase and inactivated derivatives
CIMIT_RS00660	COG3415	Transposase
CIMIT_RS00710	COG1136	(ABC) transporter
CIMIT_RS00710	COG0577	efflux transmembrane transporter activity
CIMIT_RS00720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CIMIT_RS00740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CIMIT_RS00760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIMIT_RS00765	COG3442	glutamine amidotransferase
CIMIT_RS00770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIMIT_RS00790	COG0697	spore germination
CIMIT_RS00795	COG0527	aspartate kinase activity
CIMIT_RS00800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIMIT_RS00810	COG3949	Membrane
CIMIT_RS00815	COG3949	Membrane
CIMIT_RS00830	COG1131	(ABC) transporter
CIMIT_RS00840	COG4585	Histidine kinase
CIMIT_RS00865	COG0651	ATP synthesis coupled electron transport
CIMIT_RS00875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CIMIT_RS00875	COG2111	Na H antiporter
CIMIT_RS00900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CIMIT_RS00915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIMIT_RS00920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIMIT_RS00930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CIMIT_RS00935	COG0494	nUDIX hydrolase
CIMIT_RS00945	COG2267	carboxylic ester hydrolase activity
CIMIT_RS01000	COG1111	helicase
CIMIT_RS01000	COG1205	dead DEAH box helicase
CIMIT_RS01005	COG1278	Cold shock
CIMIT_RS01015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIMIT_RS01015	COG1754	DNA topoisomerase type I activity
CIMIT_RS01060	COG0318	PFAM AMP-dependent synthetase and ligase
CIMIT_RS01085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIMIT_RS01105	COG0463	Glycosyl transferase, family 2
CIMIT_RS01130	COG1088	dTDP-glucose 4,6-dehydratase activity
CIMIT_RS01140	COG1505	serine-type exopeptidase activity
CIMIT_RS01155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CIMIT_RS01165	COG1053	succinate dehydrogenase
CIMIT_RS01170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CIMIT_RS01180	COG2733	membrane
CIMIT_RS01215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CIMIT_RS01220	COG0318	PFAM AMP-dependent synthetase and ligase
CIMIT_RS01225	COG0318	PFAM AMP-dependent synthetase and ligase
CIMIT_RS01245	COG0588	phosphoglycerate mutase activity
CIMIT_RS01250	COG5002	protein histidine kinase activity
CIMIT_RS01255	COG0745	RESPONSE REGULATOR receiver
CIMIT_RS01275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIMIT_RS01295	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CIMIT_RS01300	COG0181	hydroxymethylbilane synthase activity
CIMIT_RS01310	COG0113	porphobilinogen synthase activity
CIMIT_RS01325	COG2217	Heavy metal translocating P-type atpase
CIMIT_RS01330	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CIMIT_RS01340	COG0477	Major facilitator Superfamily
CIMIT_RS01360	COG0406	alpha-ribazole phosphatase activity
CIMIT_RS01370	COG0785	Cytochrome C biogenesis protein
CIMIT_RS01375	COG1333	cytochrome c biogenesis protein
CIMIT_RS01380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CIMIT_RS01460	COG2197	response regulator
CIMIT_RS01465	COG1131	(ABC) transporter
CIMIT_RS01510	COG4948	Mandelate Racemase Muconate Lactonizing
CIMIT_RS01515	COG0471	metal ion transport
CIMIT_RS01525	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CIMIT_RS01535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIMIT_RS01535	COG0438	transferase activity, transferring glycosyl groups
CIMIT_RS01540	COG1321	iron dependent repressor
CIMIT_RS01545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CIMIT_RS01550	COG1121	(ABC) transporter
CIMIT_RS01560	COG2226	methyltransferase
CIMIT_RS01565	COG0644	oxidoreductase
CIMIT_RS01570	COG0142	geranyltranstransferase activity
CIMIT_RS01595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CIMIT_RS01605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIMIT_RS01610	COG0081	regulation of translation
CIMIT_RS01630	COG1121	(ABC) transporter
CIMIT_RS01635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CIMIT_RS01645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIMIT_RS01670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIMIT_RS01685	COG0049	tRNA binding
CIMIT_RS01690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIMIT_RS01695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIMIT_RS01730	COG1302	Protein conserved in bacteria
CIMIT_RS01735	COG0051	transcription antitermination factor activity, RNA binding
CIMIT_RS01745	COG0088	Forms part of the polypeptide exit tunnel
CIMIT_RS01750	COG0089	rRNA binding
CIMIT_RS01755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIMIT_RS01760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIMIT_RS01765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIMIT_RS01775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIMIT_RS01785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIMIT_RS01805	COG0659	secondary active sulfate transmembrane transporter activity
CIMIT_RS01810	COG2146	nitrite reductase [NAD(P)H] activity
CIMIT_RS01810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIMIT_RS01815	COG2146	nitrite reductase [NAD(P)H] activity
CIMIT_RS01815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIMIT_RS01820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CIMIT_RS01830	COG1621	beta-fructofuranosidase activity
CIMIT_RS01850	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIMIT_RS01860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CIMIT_RS01880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CIMIT_RS01910	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIMIT_RS01915	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIMIT_RS01920	COG1841	ribosomal large subunit assembly
CIMIT_RS01925	COG0200	Binds to the 23S rRNA
CIMIT_RS01935	COG2011	ABC-type metal ion transport system permease component
CIMIT_RS01940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIMIT_RS01950	COG0201	protein transport
CIMIT_RS01975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIMIT_RS01980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIMIT_RS02000	COG0101	tRNA pseudouridine synthase activity
CIMIT_RS02010	COG3266	domain, Protein
CIMIT_RS02015	COG1404	Belongs to the peptidase S8 family
CIMIT_RS02025	COG1674	ftsk spoiiie
CIMIT_RS02075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CIMIT_RS02080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIMIT_RS02110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIMIT_RS02115	COG0802	atpase or kinase
CIMIT_RS02130	COG0456	acetyltransferase
CIMIT_RS02145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIMIT_RS02150	COG0459	protein refolding
CIMIT_RS02180	COG0516	GMP reductase activity
CIMIT_RS02195	COG0519	Catalyzes the synthesis of GMP from XMP
CIMIT_RS02195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CIMIT_RS02210	COG2197	response regulator
CIMIT_RS02240	COG2011	ABC-type metal ion transport system permease component
CIMIT_RS02255	COG1464	Belongs to the NlpA lipoprotein family
CIMIT_RS02265	COG2318	DinB family
CIMIT_RS02270	COG0587	DNA-directed DNA polymerase activity
CIMIT_RS02295	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CIMIT_RS02315	COG3842	ATPase activity
CIMIT_RS02325	COG1178	ABC-type Fe3 transport system permease component
CIMIT_RS02335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIMIT_RS02340	COG2873	o-acetylhomoserine
CIMIT_RS02355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CIMIT_RS02365	COG1131	(ABC) transporter
CIMIT_RS02370	COG2186	Transcriptional regulator
CIMIT_RS02380	COG2838	Isocitrate dehydrogenase
CIMIT_RS02390	COG2860	membrane
CIMIT_RS02395	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CIMIT_RS02405	COG0180	Tryptophanyl-tRNA synthetase
CIMIT_RS02410	COG1295	ribonuclease BN
CIMIT_RS02415	COG1686	Belongs to the peptidase S11 family
CIMIT_RS02420	COG2860	membrane
CIMIT_RS02445	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CIMIT_RS02445	COG1473	amidohydrolase
CIMIT_RS02460	COG2079	MmgE PrpD family protein
CIMIT_RS02465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CIMIT_RS02470	COG0372	Belongs to the citrate synthase family
CIMIT_RS02490	COG0456	acetyltransferase
CIMIT_RS02500	COG4770	biotin carboxylase activity
CIMIT_RS02505	COG2897	thiosulfate sulfurtransferase activity
CIMIT_RS02510	COG0189	ligase activity
CIMIT_RS02530	COG0424	maF-like protein
CIMIT_RS02540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIMIT_RS02545	COG1074	ATP-dependent DNA helicase activity
CIMIT_RS02555	COG1074	ATP-dependent DNA helicase activity
CIMIT_RS02580	COG0604	alcohol dehydrogenase
CIMIT_RS02580	COG3321	synthase
CIMIT_RS02585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIMIT_RS02590	COG0736	holo-[acyl-carrier-protein] synthase activity
CIMIT_RS02595	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CIMIT_RS02595	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CIMIT_RS02605	COG3527	Alpha-acetolactate decarboxylase
CIMIT_RS02640	COG2022	thiamine diphosphate biosynthetic process
CIMIT_RS02650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIMIT_RS02655	COG0352	thiamine-phosphate diphosphorylase activity
CIMIT_RS02660	COG0352	thiamine-phosphate diphosphorylase activity
CIMIT_RS02660	COG0351	phosphomethylpyrimidine kinase
CIMIT_RS02660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIMIT_RS02700	COG1316	TRANSCRIPTIONal
CIMIT_RS02740	COG1482	cell wall glycoprotein biosynthetic process
CIMIT_RS02765	COG0745	RESPONSE REGULATOR receiver
CIMIT_RS02770	COG5002	protein histidine kinase activity
CIMIT_RS02785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIMIT_RS02805	COG1162	GTPase activity
CIMIT_RS02810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CIMIT_RS02815	COG2135	peptidase activity
CIMIT_RS02830	COG5662	AntiSigma factor
CIMIT_RS02855	COG0513	Belongs to the DEAD box helicase family
CIMIT_RS02875	COG1074	ATP-dependent DNA helicase activity
CIMIT_RS02890	COG2816	NAD+ diphosphatase activity
CIMIT_RS02935	COG2271	Major facilitator Superfamily
CIMIT_RS02950	COG2375	cellular response to nickel ion
CIMIT_RS02950	COG1132	(ABC) transporter
CIMIT_RS02955	COG1132	(ABC) transporter
CIMIT_RS02965	COG2204	response regulator
CIMIT_RS02970	COG3852	Histidine kinase
CIMIT_RS02975	COG0471	metal ion transport
CIMIT_RS02980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CIMIT_RS02990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIMIT_RS02995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CIMIT_RS03030	COG0483	inositol monophosphate 1-phosphatase activity
CIMIT_RS03035	COG0483	inositol monophosphate 1-phosphatase activity
CIMIT_RS03050	COG0477	Major facilitator Superfamily
CIMIT_RS03055	COG0511	ligase activity, forming carbon-carbon bonds
CIMIT_RS03055	COG5016	pyruvate
CIMIT_RS03060	COG0511	ligase activity, forming carbon-carbon bonds
CIMIT_RS03065	COG0439	Biotin carboxylase
CIMIT_RS03095	COG1012	belongs to the aldehyde dehydrogenase family
CIMIT_RS03100	COG2884	Cell division ATP-binding protein ftsE
CIMIT_RS03105	COG2177	Part of the ABC transporter FtsEX involved in
CIMIT_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
CIMIT_RS03180	COG1652	LysM domain
CIMIT_RS03210	COG2252	PERMEase
CIMIT_RS03215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIMIT_RS03235	COG0372	Belongs to the citrate synthase family
CIMIT_RS03240	COG0545	Peptidyl-prolyl cis-trans isomerase
CIMIT_RS03255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIMIT_RS03265	COG3757	hydrolase, family 25
CIMIT_RS03290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CIMIT_RS03295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIMIT_RS03300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIMIT_RS03305	COG1218	3'(2'),5'-bisphosphate nucleotidase
CIMIT_RS03310	COG1201	RNA secondary structure unwinding
CIMIT_RS03315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CIMIT_RS03320	COG0586	Pfam SNARE associated Golgi protein
CIMIT_RS03340	COG1605	Chorismate mutase
CIMIT_RS03410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CIMIT_RS03425	COG2197	response regulator
CIMIT_RS03430	COG4585	Histidine kinase
CIMIT_RS03440	COG0254	rRNA binding
CIMIT_RS03455	COG2205	protein histidine kinase activity
CIMIT_RS03460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIMIT_RS03465	COG0521	Mo-molybdopterin cofactor biosynthetic process
CIMIT_RS03465	COG0315	cyclic pyranopterin monophosphate synthase activity
CIMIT_RS03485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIMIT_RS03490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CIMIT_RS03515	COG0464	growth
CIMIT_RS03530	COG2818	Glycosylase
CIMIT_RS03535	COG2259	Doxx family
CIMIT_RS03545	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CIMIT_RS03555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CIMIT_RS03565	COG2267	carboxylic ester hydrolase activity
CIMIT_RS03575	COG0084	hydrolase, TatD family'
CIMIT_RS03580	COG3583	domain protein
CIMIT_RS03585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CIMIT_RS03590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIMIT_RS03595	COG0488	(ABC) transporter
CIMIT_RS03615	COG2326	polyphosphate kinase activity
CIMIT_RS03620	COG2094	Belongs to the DNA glycosylase MPG family
CIMIT_RS03625	COG0561	phosphatase activity
CIMIT_RS03630	COG1024	Enoyl-CoA hydratase
CIMIT_RS03645	COG0438	transferase activity, transferring glycosyl groups
CIMIT_RS03680	COG0471	metal ion transport
CIMIT_RS03715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CIMIT_RS03725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CIMIT_RS03730	COG0569	domain protein
CIMIT_RS03735	COG0431	NADPH-dependent FMN reductase
CIMIT_RS03740	COG0193	aminoacyl-tRNA hydrolase activity
CIMIT_RS03750	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIMIT_RS03755	COG0193	aminoacyl-tRNA hydrolase activity
CIMIT_RS03760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CIMIT_RS03775	COG1113	amino acid transport
CIMIT_RS03780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIMIT_RS03785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIMIT_RS03795	COG2132	Multicopper oxidase
CIMIT_RS03800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CIMIT_RS03800	COG2755	lipolytic protein G-D-S-L family
CIMIT_RS03850	COG1028	Short-chain dehydrogenase reductase Sdr
CIMIT_RS03880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CIMIT_RS03895	COG1072	(Pantothenic acid kinase))
CIMIT_RS03900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIMIT_RS03950	COG0114	fumarate hydratase activity
CIMIT_RS03955	COG1494	fructose-1,6-bisphosphatase
CIMIT_RS03965	COG1722	exodeoxyribonuclease VII activity
CIMIT_RS03985	COG1322	Protein conserved in bacteria
CIMIT_RS03995	COG0012	GTP binding
CIMIT_RS04010	COG1136	(ABC) transporter
CIMIT_RS04010	COG0577	efflux transmembrane transporter activity
CIMIT_RS04020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CIMIT_RS04045	COG0640	Transcriptional regulator
CIMIT_RS04090	COG0789	Transcriptional regulator
CIMIT_RS04100	COG1120	ATPase activity
CIMIT_RS04105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIMIT_RS04120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIMIT_RS04170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIMIT_RS04190	COG1136	(ABC) transporter
CIMIT_RS04190	COG0577	efflux transmembrane transporter activity
CIMIT_RS04225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIMIT_RS04230	COG4120	Belongs to the binding-protein-dependent transport system permease family
CIMIT_RS04255	COG0789	Transcriptional regulator
CIMIT_RS04270	COG0243	molybdopterin cofactor binding
CIMIT_RS04275	COG0243	molybdopterin cofactor binding
CIMIT_RS04275	COG3383	formate dehydrogenase (NAD+) activity
CIMIT_RS04280	COG0437	4 iron, 4 sulfur cluster binding
CIMIT_RS04290	COG0709	Synthesizes selenophosphate from selenide and ATP
CIMIT_RS04320	COG2354	Protein conserved in bacteria
CIMIT_RS04325	COG4166	transmembrane transport
CIMIT_RS04330	COG0601	transmembrane transport
CIMIT_RS04335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIMIT_RS04345	COG4721	ABC-type cobalt transport system, permease component
CIMIT_RS04350	COG1122	ATPase activity
CIMIT_RS04360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CIMIT_RS04360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CIMIT_RS04375	COG1217	gtp-binding protein TYPA
CIMIT_RS04420	COG1113	amino acid transport
CIMIT_RS04425	COG1113	amino acid transport
CIMIT_RS04435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CIMIT_RS04445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CIMIT_RS04450	COG0463	Glycosyl transferase, family 2
CIMIT_RS04460	COG2226	methyltransferase
CIMIT_RS04470	COG0297	glycogen (starch) synthase activity
CIMIT_RS04475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CIMIT_RS04500	COG0489	protein tyrosine kinase activity
CIMIT_RS04500	COG2151	metal-sulfur cluster biosynthetic enzyme
CIMIT_RS04515	COG0508	dehydrogenase complex catalyzes the overall conversion of
CIMIT_RS04515	COG0567	Dehydrogenase, E1 component
CIMIT_RS04520	COG1132	(ABC) transporter
CIMIT_RS04530	COG2272	Belongs to the type-B carboxylesterase lipase family
CIMIT_RS04565	COG1122	ATPase activity
CIMIT_RS04575	COG0039	L-malate dehydrogenase activity
CIMIT_RS04595	COG0745	RESPONSE REGULATOR receiver
CIMIT_RS04600	COG2205	protein histidine kinase activity
CIMIT_RS04605	COG2851	Citrate transporter
CIMIT_RS04635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIMIT_RS04640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CIMIT_RS04650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CIMIT_RS04685	COG0640	Transcriptional regulator
CIMIT_RS04690	COG0798	PFAM Bile acid sodium symporter
CIMIT_RS04695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIMIT_RS04730	COG1484	DNA-dependent DNA replication
CIMIT_RS04760	COG1556	Lactate utilization protein
CIMIT_RS04765	COG1139	Iron-sulfur cluster binding protein
CIMIT_RS04770	COG0247	lactate metabolic process
CIMIT_RS04775	COG1620	l-lactate permease
CIMIT_RS04780	COG0018	arginyl-trna synthetase
CIMIT_RS04785	COG0019	diaminopimelate decarboxylase activity
CIMIT_RS04790	COG0460	homoserine dehydrogenase
CIMIT_RS04795	COG0083	homoserine kinase activity
CIMIT_RS04810	COG0521	Mo-molybdopterin cofactor biosynthetic process
CIMIT_RS04830	COG0725	ABC transporter, periplasmic molybdate-binding protein
CIMIT_RS04855	COG0315	cyclic pyranopterin monophosphate synthase activity
CIMIT_RS04865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CIMIT_RS04905	COG0356	it plays a direct role in the translocation of protons across the membrane
CIMIT_RS04910	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIMIT_RS04920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIMIT_RS04925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIMIT_RS04930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIMIT_RS04935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIMIT_RS04950	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CIMIT_RS04975	COG0366	Alpha amylase catalytic
CIMIT_RS04980	COG1119	ATPase activity
CIMIT_RS05020	COG1131	(ABC) transporter
CIMIT_RS05025	COG2197	response regulator
CIMIT_RS05030	COG4585	Histidine kinase
CIMIT_RS05035	COG0482	sulfurtransferase activity
CIMIT_RS05060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIMIT_RS05090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIMIT_RS05095	COG0154	amidase activity
CIMIT_RS05105	COG0205	6-phosphofructokinase activity
CIMIT_RS05115	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIMIT_RS05120	COG3949	Membrane
CIMIT_RS05130	COG0435	Glutathione S-transferase
CIMIT_RS05155	COG0668	transmembrane transport
CIMIT_RS05160	COG0028	Belongs to the TPP enzyme family
CIMIT_RS05170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CIMIT_RS05205	COG0473	3-isopropylmalate dehydrogenase activity
CIMIT_RS05225	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIMIT_RS05300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CIMIT_RS05305	COG0066	3-isopropylmalate dehydratase activity
CIMIT_RS05320	COG0494	nUDIX hydrolase
CIMIT_RS05320	COG0406	alpha-ribazole phosphatase activity
CIMIT_RS05340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CIMIT_RS05345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIMIT_RS05350	COG1461	Dihydroxyacetone kinase
CIMIT_RS05355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIMIT_RS05360	COG0742	ribosomal rna small subunit methyltransferase
CIMIT_RS05380	COG0765	amino acid transport
CIMIT_RS05400	COG2814	Major facilitator Superfamily
CIMIT_RS05675	COG0539	negative regulation of cytoplasmic translation
CIMIT_RS05680	COG0237	dephospho-CoA kinase activity
CIMIT_RS05695	COG4172	Belongs to the ABC transporter superfamily
CIMIT_RS05710	COG0747	negative chemotaxis
CIMIT_RS05715	COG1309	transcriptional regulator
CIMIT_RS05735	COG3973	AAA domain
CIMIT_RS05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIMIT_RS05765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIMIT_RS05775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIMIT_RS05785	COG0072	phenylalanine-tRNA ligase activity
CIMIT_RS05785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIMIT_RS05795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CIMIT_RS05805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CIMIT_RS05810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIMIT_RS05820	COG0137	argininosuccinate synthase activity
CIMIT_RS05825	COG0165	Argininosuccinate lyase
CIMIT_RS05845	COG1663	tetraacyldisaccharide 4'-kinase activity
CIMIT_RS05845	COG2835	tetraacyldisaccharide 4'-kinase activity
CIMIT_RS05850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIMIT_RS05875	COG0647	UMP catabolic process
CIMIT_RS05885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIMIT_RS05905	COG0494	nUDIX hydrolase
CIMIT_RS05910	COG4974	Belongs to the 'phage' integrase family
CIMIT_RS05925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIMIT_RS05930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIMIT_RS05935	COG1187	pseudouridine synthase activity
CIMIT_RS05940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CIMIT_RS05945	COG1160	GTP binding
CIMIT_RS05960	COG1597	lipid kinase activity
CIMIT_RS05990	COG0405	Gamma-glutamyltransferase
CIMIT_RS06010	COG3012	SEC-C Motif Domain Protein
CIMIT_RS06020	COG0653	protein targeting
CIMIT_RS06025	COG1716	ATPase activity
CIMIT_RS06050	COG1253	flavin adenine dinucleotide binding
CIMIT_RS06055	COG1253	flavin adenine dinucleotide binding
CIMIT_RS06060	COG0513	Belongs to the DEAD box helicase family
CIMIT_RS06070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIMIT_RS06080	COG0598	Magnesium transport protein CorA
CIMIT_RS06085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIMIT_RS06095	COG1882	Formate acetyltransferase
CIMIT_RS06100	COG0446	pyridine nucleotide-disulphide oxidoreductase
CIMIT_RS06110	COG2353	YceI-like domain
CIMIT_RS06125	COG0463	Glycosyl transferase, family 2
CIMIT_RS06145	COG0300	oxidoreductase activity
CIMIT_RS06165	COG0805	protein transport
CIMIT_RS06185	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CIMIT_RS06200	COG3104	oligopeptide transport
CIMIT_RS06205	COG0133	tryptophan synthase activity
CIMIT_RS06235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CIMIT_RS06240	COG0385	Bile acid
CIMIT_RS06245	COG1222	aaa ATPase
CIMIT_RS06255	COG1362	aminopeptidase activity
CIMIT_RS06270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CIMIT_RS06275	COG1027	Aspartate ammonia-lyase
CIMIT_RS06280	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CIMIT_RS06285	COG0140	phosphoribosyl-ATP diphosphatase activity
CIMIT_RS06290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CIMIT_RS06300	COG0215	cysteine-tRNA ligase activity
CIMIT_RS06305	COG1968	undecaprenyl-diphosphatase activity
CIMIT_RS06365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CIMIT_RS06370	COG0791	NLP P60 protein
CIMIT_RS06370	COG3883	PFAM NLP P60 protein
CIMIT_RS06380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CIMIT_RS06400	COG3830	Belongs to the UPF0237 family
CIMIT_RS06405	COG2848	UPF0210 protein
CIMIT_RS06430	COG0488	(ABC) transporter
CIMIT_RS06435	COG2151	metal-sulfur cluster biosynthetic enzyme
CIMIT_RS06440	COG0822	iron-sulfur transferase activity
CIMIT_RS06445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIMIT_RS06450	COG0396	ATPase activity
CIMIT_RS06485	COG1612	heme a metabolic process
CIMIT_RS06505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CIMIT_RS06520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CIMIT_RS06525	COG0149	triose-phosphate isomerase activity
CIMIT_RS06530	COG0126	phosphoglycerate kinase activity
CIMIT_RS06535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CIMIT_RS06540	COG1481	regulation of sporulation
CIMIT_RS06550	COG1660	Displays ATPase and GTPase activities
CIMIT_RS06555	COG0322	excinuclease ABC activity
CIMIT_RS06565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CIMIT_RS06595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIMIT_RS06600	COG0242	peptide deformylase activity
CIMIT_RS06610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIMIT_RS06625	COG1758	RNA polymerase activity
CIMIT_RS06630	COG0194	GDP metabolic process
CIMIT_RS06640	COG0284	orotidine-5'-phosphate decarboxylase activity
CIMIT_RS06645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CIMIT_RS06650	COG0505	Belongs to the CarA family
CIMIT_RS06655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CIMIT_RS06660	COG0540	Belongs to the ATCase OTCase family
CIMIT_RS06665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIMIT_RS06680	COG2326	polyphosphate kinase activity
CIMIT_RS06685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIMIT_RS06695	COG0006	proline dipeptidase activity
CIMIT_RS06700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CIMIT_RS06710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CIMIT_RS06715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CIMIT_RS06735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIMIT_RS06755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CIMIT_RS06780	COG1760	l-serine dehydratase
CIMIT_RS06785	COG0124	histidyl-tRNA synthetase
CIMIT_RS06795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CIMIT_RS06800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIMIT_RS06810	COG0737	Belongs to the 5'-nucleotidase family
CIMIT_RS06815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIMIT_RS06830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CIMIT_RS06835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CIMIT_RS06845	COG2255	four-way junction helicase activity
CIMIT_RS06850	COG0632	four-way junction helicase activity
CIMIT_RS06855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CIMIT_RS06865	COG1946	Acyl-CoA thioesterase
CIMIT_RS06875	COG0438	transferase activity, transferring glycosyl groups
CIMIT_RS06880	COG1560	Kdo2-lipid A biosynthetic process
CIMIT_RS06885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIMIT_RS06895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIMIT_RS06900	COG2837	iron assimilation
CIMIT_RS06950	COG0482	sulfurtransferase activity
CIMIT_RS06965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIMIT_RS06990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIMIT_RS07000	COG0756	dUTP diphosphatase activity
CIMIT_RS07040	COG1061	Type III restriction enzyme res subunit
CIMIT_RS07055	COG2890	protein-(glutamine-N5) methyltransferase activity
CIMIT_RS07070	COG1321	iron dependent repressor
CIMIT_RS07075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIMIT_RS07095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIMIT_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
CIMIT_RS07110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIMIT_RS07115	COG0450	alkyl hydroperoxide reductase
CIMIT_RS07120	COG0583	DNA-binding transcription factor activity
CIMIT_RS07125	COG1643	Atp-dependent helicase
CIMIT_RS07130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIMIT_RS07145	COG1349	DNA-binding transcription factor activity
CIMIT_RS07155	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CIMIT_RS07155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CIMIT_RS07155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CIMIT_RS07160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CIMIT_RS07165	COG2233	PERMEase
CIMIT_RS07170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIMIT_RS07185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIMIT_RS07190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIMIT_RS07200	COG1196	nuclear chromosome segregation
CIMIT_RS07220	COG1126	abc transporter atp-binding protein
CIMIT_RS07225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIMIT_RS07230	COG0765	amino acid transport
CIMIT_RS07235	COG0765	amino acid transport
CIMIT_RS07240	COG2137	regulation of response to DNA damage stimulus
CIMIT_RS07255	COG1268	BioY protein
CIMIT_RS07260	COG1122	ATPase activity
CIMIT_RS07270	COG1842	Phage shock protein A
CIMIT_RS07275	COG1396	sequence-specific DNA binding
CIMIT_RS07280	COG1058	Belongs to the CinA family
CIMIT_RS07280	COG1546	Belongs to the CinA family
CIMIT_RS07305	COG1674	ftsk spoiiie
CIMIT_RS07320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIMIT_RS07325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIMIT_RS07330	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CIMIT_RS07375	COG1012	belongs to the aldehyde dehydrogenase family
CIMIT_RS07380	COG1185	polyribonucleotide nucleotidyltransferase activity
CIMIT_RS07385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIMIT_RS07400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIMIT_RS07405	COG2977	Belongs to the P-Pant transferase superfamily
CIMIT_RS07410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CIMIT_RS07420	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CIMIT_RS07425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIMIT_RS07430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIMIT_RS07445	COG0779	Required for maturation of 30S ribosomal subunits
CIMIT_RS07455	COG0442	prolyl-tRNA aminoacylation
CIMIT_RS07460	COG3022	response to hydroperoxide
CIMIT_RS07480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CIMIT_RS07490	COG1648	precorrin-2 dehydrogenase activity
CIMIT_RS07490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CIMIT_RS07495	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CIMIT_RS07500	COG0579	oxidoreductase
CIMIT_RS07530	COG0768	penicillin binding
CIMIT_RS07535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CIMIT_RS07540	COG0750	zinc metalloprotease
CIMIT_RS07545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CIMIT_RS07555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CIMIT_RS07575	COG0528	UMP kinase activity
CIMIT_RS07580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIMIT_RS07595	COG4974	Belongs to the 'phage' integrase family
CIMIT_RS07610	COG0792	nuclease activity
CIMIT_RS07620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIMIT_RS07625	COG0681	Belongs to the peptidase S26 family
CIMIT_RS07640	COG0336	Belongs to the RNA methyltransferase TrmD family
CIMIT_RS07645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIMIT_RS07655	COG0228	four-way junction DNA binding
CIMIT_RS07660	COG2755	lipolytic protein G-D-S-L family
CIMIT_RS07660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CIMIT_RS07675	COG1196	nuclear chromosome segregation
CIMIT_RS07685	COG1115	amino acid carrier protein
CIMIT_RS07690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CIMIT_RS07710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CIMIT_RS07715	COG1929	Belongs to the glycerate kinase type-1 family
CIMIT_RS07735	COG0058	SHG alpha-glucan phosphorylase activity
CIMIT_RS07740	COG0512	Glutamine amidotransferase of anthranilate synthase
CIMIT_RS07740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CIMIT_RS07755	COG0469	pyruvate kinase activity
CIMIT_RS07760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIMIT_RS07765	COG0134	indole-3-glycerol-phosphate synthase activity
CIMIT_RS07780	COG0107	imidazoleglycerol-phosphate synthase activity
CIMIT_RS07785	COG0483	inositol monophosphate 1-phosphatase activity
CIMIT_RS07790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CIMIT_RS07815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CIMIT_RS07820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CIMIT_RS07885	COG1739	Uncharacterized protein family UPF0029
CIMIT_RS07895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CIMIT_RS07920	COG0577	efflux transmembrane transporter activity
CIMIT_RS07925	COG1136	(ABC) transporter
CIMIT_RS07955	COG0488	(ABC) transporter
CIMIT_RS07965	COG0252	asparaginase activity
CIMIT_RS07975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIMIT_RS07980	COG3599	regulation of cell shape
CIMIT_RS07990	COG1799	cell septum assembly
CIMIT_RS07995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CIMIT_RS08000	COG1496	oxidoreductase activity
CIMIT_RS08005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIMIT_RS08015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CIMIT_RS08020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIMIT_RS08035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIMIT_RS08045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIMIT_RS08050	COG0768	penicillin binding
CIMIT_RS08060	COG0275	rRNA processing
CIMIT_RS08085	COG0142	geranyltranstransferase activity
CIMIT_RS08110	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CIMIT_RS08130	COG1940	carbohydrate kinase activity
CIMIT_RS08135	COG0438	transferase activity, transferring glycosyl groups
CIMIT_RS08145	COG0791	NLP P60 protein
CIMIT_RS08150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CIMIT_RS08155	COG0723	plastoquinol--plastocyanin reductase activity
CIMIT_RS08160	COG2010	Cytochrome c
CIMIT_RS08165	COG1845	cytochrome c oxidase, subunit III
CIMIT_RS08175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CIMIT_RS08200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CIMIT_RS08205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CIMIT_RS08220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CIMIT_RS08225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIMIT_RS08225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIMIT_RS08230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CIMIT_RS08235	COG0509	glycine decarboxylation via glycine cleavage system
CIMIT_RS08240	COG0321	lipoyl(octanoyl) transferase activity
CIMIT_RS08265	COG0174	glutamine synthetase
CIMIT_RS08340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CIMIT_RS08360	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CIMIT_RS08365	COG0174	glutamine synthetase
CIMIT_RS08450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CIMIT_RS08475	COG1012	belongs to the aldehyde dehydrogenase family
CIMIT_RS08500	COG0477	Major facilitator Superfamily
CIMIT_RS08515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CIMIT_RS08520	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CIMIT_RS08620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CIMIT_RS08625	COG1388	LysM domain
CIMIT_RS08625	COG1134	teichoic acid transport
CIMIT_RS08660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CIMIT_RS08710	COG3956	TIGRFAM MazG family protein
CIMIT_RS08725	COG0358	DNA primase activity
CIMIT_RS08750	COG1966	Carbon starvation protein
CIMIT_RS08760	COG0003	Pfam Anion-transporting ATPase
CIMIT_RS08765	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CIMIT_RS08785	COG0423	glycine-tRNA ligase activity
CIMIT_RS08800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIMIT_RS08805	COG1381	Involved in DNA repair and RecF pathway recombination
CIMIT_RS08865	COG0484	heat shock protein binding
CIMIT_RS08870	COG1420	regulation of RNA biosynthetic process
CIMIT_RS08885	COG1022	Amp-dependent synthetase and ligase
CIMIT_RS08910	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CIMIT_RS08920	COG1132	(ABC) transporter
CIMIT_RS08930	COG0366	Alpha amylase catalytic
CIMIT_RS08935	COG3281	Trehalose synthase
CIMIT_RS08940	COG1114	Component of the transport system for branched-chain amino acids
CIMIT_RS08945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIMIT_RS08950	COG2188	Transcriptional regulator
CIMIT_RS08955	COG0747	negative chemotaxis
CIMIT_RS08965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIMIT_RS08970	COG4172	Belongs to the ABC transporter superfamily
CIMIT_RS08975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIMIT_RS08995	COG0481	GTPase activity
CIMIT_RS09035	COG1555	photosystem II stabilization
CIMIT_RS09035	COG3568	Endonuclease Exonuclease Phosphatase
CIMIT_RS09040	COG1307	EDD domain protein, DegV family
CIMIT_RS09045	COG0406	alpha-ribazole phosphatase activity
CIMIT_RS09055	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIMIT_RS09065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIMIT_RS09095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CIMIT_RS09100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CIMIT_RS09105	COG1530	ribonuclease E activity
CIMIT_RS09115	COG0105	UTP biosynthetic process
CIMIT_RS09125	COG0318	PFAM AMP-dependent synthetase and ligase
CIMIT_RS09140	COG0285	dihydrofolate synthase activity
CIMIT_RS09160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIMIT_RS09165	COG2267	carboxylic ester hydrolase activity
CIMIT_RS09180	COG0740	serine-type endopeptidase activity
CIMIT_RS09190	COG0544	peptidyl-prolyl cis-trans isomerase activity
CIMIT_RS09210	COG2086	electron transfer activity
CIMIT_RS09215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CIMIT_RS09230	COG0156	8-amino-7-oxononanoate synthase activity
CIMIT_RS09235	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CIMIT_RS09240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CIMIT_RS09250	COG1373	ATPase (AAA superfamily
CIMIT_RS09255	COG0698	ribose 5-phosphate isomerase
CIMIT_RS09260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CIMIT_RS09275	COG0668	transmembrane transport
CIMIT_RS09305	COG1276	copper resistance
CIMIT_RS09330	COG4221	oxidoreductase activity
CIMIT_RS09335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CIMIT_RS09360	COG1376	ErfK ybiS ycfS ynhG family protein
CIMIT_RS09370	COG1335	isochorismatase
CIMIT_RS09415	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CIMIT_RS09425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CIMIT_RS09435	COG3191	aminopeptidase activity
CIMIT_RS09455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIMIT_RS09475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIMIT_RS09480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIMIT_RS09485	COG2186	Transcriptional regulator
CIMIT_RS09490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIMIT_RS09515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CIMIT_RS09520	COG2814	Major facilitator Superfamily
CIMIT_RS09525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CIMIT_RS09545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIMIT_RS09545	COG2169	Transcriptional regulator
CIMIT_RS09590	COG1115	amino acid carrier protein
CIMIT_RS09595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIMIT_RS09620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIMIT_RS09625	COG2197	response regulator
CIMIT_RS09635	COG1045	serine acetyltransferase
CIMIT_RS09655	COG1228	amidohydrolase
CIMIT_RS09660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CIMIT_RS09665	COG3314	Sporulation integral membrane protein YlbJ
CIMIT_RS09670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIMIT_RS09675	COG1960	acyl-CoA dehydrogenase activity
CIMIT_RS09680	COG2986	histidine ammonia-lyase
CIMIT_RS09685	COG0010	Belongs to the arginase family
CIMIT_RS09690	COG3314	Sporulation integral membrane protein YlbJ
CIMIT_RS09725	COG1937	Protein conserved in bacteria
CIMIT_RS09750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CIMIT_RS09770	COG0456	acetyltransferase
CIMIT_RS09830	COG0047	phosphoribosylformylglycinamidine synthase activity
CIMIT_RS09835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIMIT_RS09860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CIMIT_RS09870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIMIT_RS09875	COG0151	Belongs to the GarS family
CIMIT_RS09880	COG0537	adenosine 5'-monophosphoramidase activity
CIMIT_RS09885	COG2205	protein histidine kinase activity
CIMIT_RS09890	COG0745	RESPONSE REGULATOR receiver
CIMIT_RS09910	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CIMIT_RS09925	COG1609	Transcriptional regulator
CIMIT_RS09940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CIMIT_RS09945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIMIT_RS09950	COG0215	cysteine-tRNA ligase activity
CIMIT_RS09960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CIMIT_RS09970	COG2847	Copper chaperone PCu(A)C
CIMIT_RS09975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIMIT_RS09990	COG1194	a g-specific adenine glycosylase
CIMIT_RS09995	COG0428	transporter
CIMIT_RS10005	COG0542	response to heat
CIMIT_RS10015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIMIT_RS10020	COG3711	transcriptional antiterminator
CIMIT_RS10035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CIMIT_RS10040	COG2814	Major facilitator Superfamily
CIMIT_RS10050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CIMIT_RS10070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CIMIT_RS10085	COG0302	gtp cyclohydrolase
CIMIT_RS10090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIMIT_RS10100	COG0037	tRNA processing
CIMIT_RS10105	COG2027	D-alanyl-D-alanine carboxypeptidase
CIMIT_RS10110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CIMIT_RS10130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIMIT_RS10140	COG2326	polyphosphate kinase activity
CIMIT_RS10145	COG0459	protein refolding
CIMIT_RS10155	COG2111	Na H antiporter
CIMIT_RS10155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CIMIT_RS10160	COG1006	Multisubunit Na H antiporter MnhC subunit
CIMIT_RS10165	COG0651	ATP synthesis coupled electron transport
CIMIT_RS10225	COG0242	peptide deformylase activity
CIMIT_RS10245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIMIT_RS10255	COG1131	(ABC) transporter
CIMIT_RS10270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIMIT_RS10275	COG0515	serine threonine protein kinase
CIMIT_RS10300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIMIT_RS10305	COG0280	phosphate acetyltransferase
CIMIT_RS10320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CIMIT_RS10325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIMIT_RS10340	COG4129	membrane
CIMIT_RS10345	COG0191	fructose-bisphosphate aldolase activity
CIMIT_RS10380	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CIMIT_RS10385	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CIMIT_RS10400	COG0542	response to heat
CIMIT_RS10440	COG0028	Belongs to the TPP enzyme family
CIMIT_RS10445	COG0789	Transcriptional regulator
CIMIT_RS10450	COG0484	heat shock protein binding
CIMIT_RS10455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIMIT_RS10460	COG0443	Heat shock 70 kDa protein
CIMIT_RS10470	COG1012	belongs to the aldehyde dehydrogenase family
CIMIT_RS10485	COG0693	protein deglycase activity
CIMIT_RS10490	COG0730	response to heat
CIMIT_RS10520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIMIT_RS10525	COG0493	'glutamate synthase
CIMIT_RS10565	COG1283	sodium-dependent phosphate transmembrane transporter activity
CIMIT_RS10590	COG0069	glutamate synthase activity
CIMIT_RS10595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CIMIT_RS10625	COG1472	Belongs to the glycosyl hydrolase 3 family
CIMIT_RS10635	COG4981	capsule polysaccharide biosynthetic process
CIMIT_RS10665	COG0438	transferase activity, transferring glycosyl groups
CIMIT_RS10670	COG0500	methyltransferase
CIMIT_RS10685	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CIMIT_RS10690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CIMIT_RS10730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIMIT_RS10735	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CIMIT_RS10735	COG3321	synthase
CIMIT_RS10735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIMIT_RS10740	COG0318	PFAM AMP-dependent synthetase and ligase
CIMIT_RS10745	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CIMIT_RS10755	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CIMIT_RS10755	COG5479	isomerase activity
CIMIT_RS10765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIMIT_RS10770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CIMIT_RS10775	COG0671	phosphoesterase, PA-phosphatase related
CIMIT_RS10780	COG1216	Glycosyl transferase, family 2
CIMIT_RS10795	COG4948	Mandelate Racemase Muconate Lactonizing
CIMIT_RS10800	COG3485	protocatechuate 3,4-dioxygenase
CIMIT_RS10815	COG0543	2 iron, 2 sulfur cluster binding
CIMIT_RS10815	COG0633	Ferredoxin
CIMIT_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
CIMIT_RS10830	COG4829	muconolactone delta-isomerase
CIMIT_RS10845	COG1414	Transcriptional regulator
CIMIT_RS10850	COG0183	Belongs to the thiolase family
CIMIT_RS10870	COG1120	ATPase activity
CIMIT_RS10875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIMIT_RS10880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIMIT_RS10920	COG0561	phosphatase activity
CIMIT_RS10930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIMIT_RS10935	COG2188	Transcriptional regulator
CIMIT_RS10950	COG0077	Prephenate dehydratase
CIMIT_RS10960	COG1316	TRANSCRIPTIONal
CIMIT_RS10965	COG3842	ATPase activity
CIMIT_RS10980	COG1175	transmembrane transport
CIMIT_RS11005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIMIT_RS11030	COG2197	response regulator
CIMIT_RS11035	COG4585	Histidine kinase
CIMIT_RS11060	COG0706	membrane insertase activity
CIMIT_RS11070	COG2261	transglycosylase associated protein
CIMIT_RS11080	COG0564	pseudouridine synthase activity
CIMIT_RS11105	COG1129	ABC transporter
CIMIT_RS11110	COG2186	Transcriptional regulator
CIMIT_RS11120	COG1842	Phage shock protein A
CIMIT_RS11125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CIMIT_RS11150	COG0305	Participates in initiation and elongation during chromosome replication
CIMIT_RS11155	COG0514	ATP-dependent DNA helicase (RecQ)
CIMIT_RS11165	COG0359	binds to the 23S rRNA
CIMIT_RS11170	COG0629	single-stranded DNA binding
CIMIT_RS11190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CIMIT_RS11220	COG3311	Transcriptional regulator
CIMIT_RS11225	COG4868	Belongs to the UPF0371 family
CIMIT_RS11235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIMIT_RS11235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CIMIT_RS11240	COG0492	ferredoxin-NADP+ reductase activity
CIMIT_RS11285	COG2197	response regulator
CIMIT_RS11290	COG2814	Major facilitator Superfamily
CIMIT_RS11340	COG0495	leucyl-tRNA aminoacylation
CIMIT_RS11375	COG1518	maintenance of DNA repeat elements
CIMIT_RS11375	COG1468	defense response to virus
CIMIT_RS11380	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CIMIT_RS11400	COG2358	TRAP transporter, solute receptor (TAXI family
CIMIT_RS11435	COG3177	Filamentation induced by cAMP protein fic
CIMIT_RS11480	COG0477	Major facilitator Superfamily
CIMIT_RS11500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CIMIT_RS11530	COG2267	carboxylic ester hydrolase activity
CIMIT_RS11550	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CIMIT_RS11565	COG2239	Acts as a magnesium transporter
CIMIT_RS11590	COG1250	3-hydroxyacyl-CoA dehydrogenase
CIMIT_RS11595	COG0385	Bile acid
CIMIT_RS11605	COG0738	Major facilitator superfamily
CIMIT_RS11610	COG4948	Mandelate Racemase Muconate Lactonizing
CIMIT_RS11630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIMIT_RS11635	COG1012	belongs to the aldehyde dehydrogenase family
CIMIT_RS11640	COG3485	protocatechuate 3,4-dioxygenase
CIMIT_RS11680	COG0814	amino acid
CIMIT_RS11690	COG0604	alcohol dehydrogenase
CIMIT_RS11695	COG0814	amino acid
CIMIT_RS11705	COG3842	ATPase activity
CIMIT_RS11770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CIMIT_RS11775	COG0512	Glutamine amidotransferase of anthranilate synthase
CIMIT_RS11780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CIMIT_RS11785	COG0134	indole-3-glycerol-phosphate synthase activity
CIMIT_RS11785	COG0135	phosphoribosylanthranilate isomerase activity
CIMIT_RS11795	COG0159	tryptophan synthase activity
CIMIT_RS11805	COG1902	pentaerythritol trinitrate reductase activity
CIMIT_RS11835	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CIMIT_RS11845	COG0617	tRNA 3'-terminal CCA addition
CIMIT_RS11875	COG3118	belongs to the thioredoxin family
CIMIT_RS11880	COG3409	Peptidoglycan-binding domain 1 protein
CIMIT_RS11880	COG0860	N-Acetylmuramoyl-L-alanine amidase
CIMIT_RS11900	COG1192	Involved in chromosome partitioning
CIMIT_RS11905	COG0357	Ribosomal RNA small subunit methyltransferase G
CIMIT_RS11915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CIMIT_RS11925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CIMIT_RS11970	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIMIT_RS11995	COG4585	Histidine kinase
CIMIT_RS12110	COG1129	ABC transporter
CIMIT_RS12110	COG0842	Transport permease protein
CIMIT_RS12125	COG0740	serine-type endopeptidase activity
CIMIT_RS12145	COG1525	nuclease
CIMIT_RS12185	COG0464	growth
CIMIT_RS12190	COG3226	Transcriptional regulator