locus-tag	class	description
CLAC_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLAC_RS00010	COG0592	DNA-directed DNA polymerase activity
CLAC_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLAC_RS00025	COG0187	DNA topoisomerase II activity
CLAC_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLAC_RS00055	COG1620	l-lactate permease
CLAC_RS00065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLAC_RS00080	COG0515	serine threonine protein kinase
CLAC_RS00080	COG2815	serine threonine protein kinase
CLAC_RS00085	COG0515	serine threonine protein kinase
CLAC_RS00090	COG0768	penicillin binding
CLAC_RS00105	COG1716	ATPase activity
CLAC_RS00110	COG1716	ATPase activity
CLAC_RS00110	COG1716	ATPase activity
CLAC_RS00145	COG1652	LysM domain
CLAC_RS00155	COG0730	response to heat
CLAC_RS00160	COG0667	Aldo Keto reductase
CLAC_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
CLAC_RS00195	COG3268	Saccharopine dehydrogenase
CLAC_RS00205	COG2814	Major facilitator Superfamily
CLAC_RS00215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLAC_RS00220	COG5650	phosphatidylinositol metabolic process
CLAC_RS00230	COG1643	Atp-dependent helicase
CLAC_RS00235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLAC_RS00245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLAC_RS00255	COG1902	pentaerythritol trinitrate reductase activity
CLAC_RS00255	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLAC_RS00270	COG0657	acetylesterase activity
CLAC_RS00280	COG0300	oxidoreductase activity
CLAC_RS00285	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS00295	COG0070	glutamate synthase
CLAC_RS00295	COG0067	glutamate synthase
CLAC_RS00295	COG0069	glutamate synthase activity
CLAC_RS00310	COG0702	epimerase
CLAC_RS00320	COG1086	Polysaccharide biosynthesis protein
CLAC_RS00335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLAC_RS00345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLAC_RS00365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLAC_RS00375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CLAC_RS00390	COG2501	S4 domain
CLAC_RS00400	COG0473	3-isopropylmalate dehydrogenase activity
CLAC_RS00400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLAC_RS00415	COG4558	Periplasmic binding protein
CLAC_RS00420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS00425	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLAC_RS00435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLAC_RS00455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLAC_RS00465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLAC_RS00470	COG2390	Transcriptional regulator
CLAC_RS00475	COG3590	peptidase
CLAC_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
CLAC_RS00505	COG0277	FAD linked oxidase domain protein
CLAC_RS00530	COG1216	Glycosyl transferase, family 2
CLAC_RS00545	COG1216	Glycosyl transferase, family 2
CLAC_RS00565	COG4221	oxidoreductase activity
CLAC_RS00565	COG3321	synthase
CLAC_RS00565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLAC_RS00565	COG0604	alcohol dehydrogenase
CLAC_RS00615	COG0601	transmembrane transport
CLAC_RS00620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAC_RS00625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLAC_RS00635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLAC_RS00640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLAC_RS00645	COG0287	Prephenate dehydrogenase
CLAC_RS00660	COG3237	CsbD-like
CLAC_RS00670	COG2409	Drug exporters of the RND superfamily
CLAC_RS00675	COG0343	queuine tRNA-ribosyltransferase activity
CLAC_RS00680	COG1131	(ABC) transporter
CLAC_RS00695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLAC_RS00720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLAC_RS00740	COG1937	Protein conserved in bacteria
CLAC_RS00770	COG4585	Histidine kinase
CLAC_RS00775	COG2197	response regulator
CLAC_RS00780	COG0659	secondary active sulfate transmembrane transporter activity
CLAC_RS00785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLAC_RS00820	COG3442	glutamine amidotransferase
CLAC_RS00825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLAC_RS00840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLAC_RS00855	COG0697	spore germination
CLAC_RS00860	COG0527	aspartate kinase activity
CLAC_RS00910	COG1136	(ABC) transporter
CLAC_RS00910	COG0577	efflux transmembrane transporter activity
CLAC_RS00945	COG1863	multisubunit Na H antiporter MnhE subunit
CLAC_RS00950	COG0651	ATP synthesis coupled electron transport
CLAC_RS00955	COG1006	Multisubunit Na H antiporter MnhC subunit
CLAC_RS00960	COG2111	Na H antiporter
CLAC_RS00960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLAC_RS00970	COG1408	metallophosphoesterase
CLAC_RS01000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLAC_RS01015	COG0494	nUDIX hydrolase
CLAC_RS01045	COG2826	transposase and inactivated derivatives, IS30 family
CLAC_RS01085	COG1111	helicase
CLAC_RS01085	COG1205	dead DEAH box helicase
CLAC_RS01095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLAC_RS01095	COG1754	DNA topoisomerase type I activity
CLAC_RS01115	COG3655	Transcriptional regulator
CLAC_RS01125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLAC_RS01135	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLAC_RS01145	COG1113	amino acid transport
CLAC_RS01150	COG0477	Major facilitator Superfamily
CLAC_RS01160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLAC_RS01200	COG1505	serine-type exopeptidase activity
CLAC_RS01205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLAC_RS01210	COG3800	Transcriptional regulator
CLAC_RS01210	COG1396	sequence-specific DNA binding
CLAC_RS01230	COG2224	Isocitrate lyase
CLAC_RS01235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLAC_RS01260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLAC_RS01285	COG1053	succinate dehydrogenase
CLAC_RS01290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLAC_RS01300	COG2733	membrane
CLAC_RS01330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLAC_RS01335	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS01340	COG0438	transferase activity, transferring glycosyl groups
CLAC_RS01350	COG0588	phosphoglycerate mutase activity
CLAC_RS01355	COG5002	protein histidine kinase activity
CLAC_RS01380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLAC_RS01400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLAC_RS01405	COG0181	hydroxymethylbilane synthase activity
CLAC_RS01410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLAC_RS01410	COG1587	Uroporphyrinogen-III synthase
CLAC_RS01440	COG0406	alpha-ribazole phosphatase activity
CLAC_RS01450	COG0785	Cytochrome C biogenesis protein
CLAC_RS01460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLAC_RS01475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLAC_RS01490	COG0596	Alpha beta hydrolase
CLAC_RS01510	COG3949	Membrane
CLAC_RS01525	COG1131	(ABC) transporter
CLAC_RS01530	COG2197	response regulator
CLAC_RS01540	COG1002	Type II restriction enzyme, methylase subunits
CLAC_RS01545	COG2184	nucleotidyltransferase activity
CLAC_RS01570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLAC_RS01590	COG0601	transmembrane transport
CLAC_RS01595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAC_RS01600	COG0444	Belongs to the ABC transporter superfamily
CLAC_RS01605	COG4608	Belongs to the ABC transporter superfamily
CLAC_RS01620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS01625	COG1120	ATPase activity
CLAC_RS01635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLAC_RS01640	COG4948	Mandelate Racemase Muconate Lactonizing
CLAC_RS01645	COG2814	Major facilitator Superfamily
CLAC_RS01650	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CLAC_RS01660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLAC_RS01660	COG0438	transferase activity, transferring glycosyl groups
CLAC_RS01675	COG0142	geranyltranstransferase activity
CLAC_RS01690	COG1132	(ABC) transporter
CLAC_RS01695	COG1132	(ABC) transporter
CLAC_RS01700	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CLAC_RS01735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS01740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS01775	COG0250	Participates in transcription elongation, termination and antitermination
CLAC_RS01780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLAC_RS01795	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLAC_RS01800	COG0222	ribosome binding
CLAC_RS01820	COG1121	(ABC) transporter
CLAC_RS01825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLAC_RS01840	COG0085	RNA polymerase activity
CLAC_RS01845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLAC_RS01850	COG0829	nickel cation binding
CLAC_RS01855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLAC_RS01865	COG0804	urea catabolic process
CLAC_RS01875	COG0831	urea catabolic process
CLAC_RS01890	COG0049	tRNA binding
CLAC_RS01900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLAC_RS01905	COG0051	transcription antitermination factor activity, RNA binding
CLAC_RS01910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLAC_RS01915	COG0088	Forms part of the polypeptide exit tunnel
CLAC_RS01920	COG0089	rRNA binding
CLAC_RS01925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLAC_RS01930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLAC_RS01940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLAC_RS01945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLAC_RS01950	COG0255	Belongs to the universal ribosomal protein uL29 family
CLAC_RS01965	COG2072	flavoprotein involved in K transport
CLAC_RS01970	COG2813	Specifically methylates the guanine in position
CLAC_RS01995	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLAC_RS02015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLAC_RS02025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLAC_RS02030	COG1841	ribosomal large subunit assembly
CLAC_RS02035	COG0200	Binds to the 23S rRNA
CLAC_RS02040	COG0156	8-amino-7-oxononanoate synthase activity
CLAC_RS02045	COG0201	protein transport
CLAC_RS02070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLAC_RS02080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLAC_RS02085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLAC_RS02125	COG1404	Belongs to the peptidase S8 family
CLAC_RS02135	COG1674	ftsk spoiiie
CLAC_RS02175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLAC_RS02180	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CLAC_RS02205	COG3425	synthase
CLAC_RS02230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLAC_RS02245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLAC_RS02245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLAC_RS02250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLAC_RS02260	COG0456	acetyltransferase
CLAC_RS02265	COG0028	Belongs to the TPP enzyme family
CLAC_RS02280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLAC_RS02285	COG0459	protein refolding
CLAC_RS02305	COG0516	GMP reductase activity
CLAC_RS02330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLAC_RS02345	COG2011	ABC-type metal ion transport system permease component
CLAC_RS02350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLAC_RS02355	COG1464	Belongs to the NlpA lipoprotein family
CLAC_RS02360	COG0587	DNA-directed DNA polymerase activity
CLAC_RS02370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLAC_RS02375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLAC_RS02385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLAC_RS02390	COG2873	o-acetylhomoserine
CLAC_RS02395	COG1201	RNA secondary structure unwinding
CLAC_RS02400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLAC_RS02405	COG2838	Isocitrate dehydrogenase
CLAC_RS02415	COG2814	Major facilitator Superfamily
CLAC_RS02435	COG0180	Tryptophanyl-tRNA synthetase
CLAC_RS02440	COG1295	ribonuclease BN
CLAC_RS02445	COG1686	Belongs to the peptidase S11 family
CLAC_RS02460	COG0791	NLP P60 protein
CLAC_RS02470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLAC_RS02480	COG1473	amidohydrolase
CLAC_RS02480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CLAC_RS02490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLAC_RS02495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLAC_RS02500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLAC_RS02505	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLAC_RS02510	COG3304	Inner membrane component domain
CLAC_RS02535	COG1605	Chorismate mutase
CLAC_RS02565	COG0138	bifunctional purine biosynthesis protein purh
CLAC_RS02575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLAC_RS02585	COG1960	acyl-CoA dehydrogenase activity
CLAC_RS02600	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS02605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLAC_RS02615	COG0183	Belongs to the thiolase family
CLAC_RS02620	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS02635	COG0298	carbon dioxide binding
CLAC_RS02640	COG0309	Hydrogenase expression formation protein (HypE)
CLAC_RS02645	COG1279	arginine transmembrane transporter activity
CLAC_RS02650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLAC_RS02655	COG0375	protein maturation
CLAC_RS02670	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CLAC_RS02675	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CLAC_RS02680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLAC_RS02685	COG0375	protein maturation
CLAC_RS02690	COG3259	Nickel-dependent hydrogenase
CLAC_RS02695	COG0298	carbon dioxide binding
CLAC_RS02700	COG1316	TRANSCRIPTIONal
CLAC_RS02745	COG1482	cell wall glycoprotein biosynthetic process
CLAC_RS02770	COG0745	RESPONSE REGULATOR receiver
CLAC_RS02775	COG5002	protein histidine kinase activity
CLAC_RS02780	COG5401	PFAM Sporulation and spore germination
CLAC_RS02790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLAC_RS02795	COG0653	protein targeting
CLAC_RS02830	COG1162	GTPase activity
CLAC_RS02835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLAC_RS02845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLAC_RS02850	COG1595	DNA-templated transcription, initiation
CLAC_RS02855	COG5662	AntiSigma factor
CLAC_RS02870	COG1597	lipid kinase activity
CLAC_RS02885	COG0513	Belongs to the DEAD box helicase family
CLAC_RS02905	COG1074	ATP-dependent DNA helicase activity
CLAC_RS02915	COG0475	glutathione-regulated potassium exporter activity
CLAC_RS02915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLAC_RS02940	COG3480	Lon protease (S16) C-terminal proteolytic domain
CLAC_RS02945	COG1115	amino acid carrier protein
CLAC_RS02955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLAC_RS02990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLAC_RS02995	COG2814	Major facilitator Superfamily
CLAC_RS03000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLAC_RS03015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLAC_RS03020	COG0813	purine-nucleoside phosphorylase activity
CLAC_RS03030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLAC_RS03035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLAC_RS03050	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS03060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLAC_RS03065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLAC_RS03075	COG3191	aminopeptidase activity
CLAC_RS03085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLAC_RS03090	COG1234	tRNA 3'-trailer cleavage
CLAC_RS03095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLAC_RS03100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLAC_RS03165	COG1376	ErfK ybiS ycfS ynhG family protein
CLAC_RS03170	COG2197	response regulator
CLAC_RS03175	COG4585	Histidine kinase
CLAC_RS03180	COG0577	efflux transmembrane transporter activity
CLAC_RS03185	COG1136	(ABC) transporter
CLAC_RS03185	COG0577	efflux transmembrane transporter activity
CLAC_RS03195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLAC_RS03460	COG3336	cytochrome c oxidase
CLAC_RS03515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CLAC_RS03520	COG0535	radical SAM domain protein
CLAC_RS03525	COG0698	ribose 5-phosphate isomerase
CLAC_RS03555	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLAC_RS03560	COG0740	serine-type endopeptidase activity
CLAC_RS03565	COG0740	serine-type endopeptidase activity
CLAC_RS03580	COG0039	L-malate dehydrogenase activity
CLAC_RS03585	COG0525	valine-tRNA ligase activity
CLAC_RS03590	COG0285	dihydrofolate synthase activity
CLAC_RS03600	COG0105	UTP biosynthetic process
CLAC_RS03605	COG1530	ribonuclease E activity
CLAC_RS03610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLAC_RS03615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLAC_RS03620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLAC_RS03625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLAC_RS03630	COG3764	Sortase (surface protein transpeptidase)
CLAC_RS03635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLAC_RS03640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLAC_RS03645	COG1780	Probably involved in ribonucleotide reductase function
CLAC_RS03655	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLAC_RS03660	COG0799	negative regulation of ribosome biogenesis
CLAC_RS03665	COG0406	alpha-ribazole phosphatase activity
CLAC_RS03670	COG1307	EDD domain protein, DegV family
CLAC_RS03690	COG0268	Binds directly to 16S ribosomal RNA
CLAC_RS03710	COG0385	Bile acid
CLAC_RS03720	COG2873	o-acetylhomoserine
CLAC_RS03730	COG0406	alpha-ribazole phosphatase activity
CLAC_RS03740	COG0095	Lipoate-protein ligase
CLAC_RS03755	COG0789	Transcriptional regulator
CLAC_RS03790	COG2130	NADP-dependent
CLAC_RS03800	COG2860	membrane
CLAC_RS03830	COG1966	Carbon starvation protein
CLAC_RS03835	COG2271	Major facilitator Superfamily
CLAC_RS03850	COG1121	(ABC) transporter
CLAC_RS03855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLAC_RS03880	COG1113	amino acid transport
CLAC_RS03885	COG3321	synthase
CLAC_RS03885	COG0604	alcohol dehydrogenase
CLAC_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
CLAC_RS03890	COG0385	Bile acid
CLAC_RS03900	COG1914	H( )-stimulated, divalent metal cation uptake system
CLAC_RS03905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLAC_RS03910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLAC_RS03915	COG1984	allophanate hydrolase subunit 2
CLAC_RS03935	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CLAC_RS03940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CLAC_RS03965	COG0477	Major facilitator Superfamily
CLAC_RS03975	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLAC_RS03980	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLAC_RS03985	COG0493	'glutamate synthase
CLAC_RS03995	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CLAC_RS04010	COG1362	aminopeptidase activity
CLAC_RS04015	COG1473	amidohydrolase
CLAC_RS04020	COG0366	Alpha amylase catalytic
CLAC_RS04035	COG4721	ABC-type cobalt transport system, permease component
CLAC_RS04040	COG1122	ATPase activity
CLAC_RS04085	COG1217	gtp-binding protein TYPA
CLAC_RS04090	COG4166	transmembrane transport
CLAC_RS04115	COG0564	pseudouridine synthase activity
CLAC_RS04145	COG1113	amino acid transport
CLAC_RS04160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLAC_RS04165	COG1611	Belongs to the LOG family
CLAC_RS04170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLAC_RS04180	COG3527	Alpha-acetolactate decarboxylase
CLAC_RS04185	COG0297	glycogen (starch) synthase activity
CLAC_RS04190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLAC_RS04195	COG4122	O-methyltransferase activity
CLAC_RS04210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLAC_RS04215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLAC_RS04240	COG0598	Magnesium transport protein CorA
CLAC_RS04250	COG0567	Dehydrogenase, E1 component
CLAC_RS04250	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLAC_RS04255	COG1132	(ABC) transporter
CLAC_RS04300	COG2814	Major facilitator Superfamily
CLAC_RS04305	COG0385	Bile acid
CLAC_RS04310	COG1301	dicarboxylic acid transport
CLAC_RS04330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLAC_RS04335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLAC_RS04375	COG4139	cobalamin transport
CLAC_RS04380	COG1120	ATPase activity
CLAC_RS04405	COG1556	Lactate utilization protein
CLAC_RS04410	COG1139	Iron-sulfur cluster binding protein
CLAC_RS04415	COG0247	lactate metabolic process
CLAC_RS04420	COG0018	arginyl-trna synthetase
CLAC_RS04425	COG0019	diaminopimelate decarboxylase activity
CLAC_RS04430	COG0460	homoserine dehydrogenase
CLAC_RS04435	COG0083	homoserine kinase activity
CLAC_RS04440	COG3384	dioxygenase
CLAC_RS04445	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS04455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLAC_RS04470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLAC_RS04480	COG0356	it plays a direct role in the translocation of protons across the membrane
CLAC_RS04485	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLAC_RS04490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLAC_RS04495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLAC_RS04500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLAC_RS04505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLAC_RS04510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLAC_RS04525	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CLAC_RS04560	COG0366	Alpha amylase catalytic
CLAC_RS04565	COG1119	ATPase activity
CLAC_RS04585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CLAC_RS04595	COG0482	sulfurtransferase activity
CLAC_RS04615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLAC_RS04620	COG0058	SHG alpha-glucan phosphorylase activity
CLAC_RS04630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLAC_RS04635	COG0154	amidase activity
CLAC_RS04640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS04645	COG1120	ATPase activity
CLAC_RS04655	COG0205	6-phosphofructokinase activity
CLAC_RS04660	COG3949	Membrane
CLAC_RS04690	COG0129	dihydroxy-acid dehydratase activity
CLAC_RS04700	COG0668	transmembrane transport
CLAC_RS04705	COG0028	Belongs to the TPP enzyme family
CLAC_RS04715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLAC_RS04735	COG0523	cobalamin synthesis protein
CLAC_RS04745	COG0473	3-isopropylmalate dehydrogenase activity
CLAC_RS04755	COG0517	IMP dehydrogenase activity
CLAC_RS04760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLAC_RS04765	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLAC_RS04780	COG3622	Belongs to the hyi family
CLAC_RS04790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLAC_RS04815	COG0039	L-malate dehydrogenase activity
CLAC_RS04880	COG2271	Major facilitator Superfamily
CLAC_RS04890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLAC_RS04895	COG0066	3-isopropylmalate dehydratase activity
CLAC_RS04900	COG0406	alpha-ribazole phosphatase activity
CLAC_RS04900	COG0494	nUDIX hydrolase
CLAC_RS04905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLAC_RS04910	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLAC_RS04920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLAC_RS04925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLAC_RS04930	COG1461	Dihydroxyacetone kinase
CLAC_RS04935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLAC_RS04945	COG0742	ribosomal rna small subunit methyltransferase
CLAC_RS04965	COG0571	ribonuclease III activity
CLAC_RS04975	COG1115	amino acid carrier protein
CLAC_RS04980	COG1254	Belongs to the acylphosphatase family
CLAC_RS04985	COG1196	nuclear chromosome segregation
CLAC_RS05030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLAC_RS05035	COG0336	Belongs to the RNA methyltransferase TrmD family
CLAC_RS05045	COG0671	phosphoesterase, PA-phosphatase related
CLAC_RS05065	COG0335	large ribosomal subunit rRNA binding
CLAC_RS05070	COG0681	Belongs to the peptidase S26 family
CLAC_RS05085	COG0792	nuclease activity
CLAC_RS05100	COG4974	Belongs to the 'phage' integrase family
CLAC_RS05110	COG0052	Belongs to the universal ribosomal protein uS2 family
CLAC_RS05125	COG0233	cytoplasmic translational termination
CLAC_RS05140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLAC_RS05155	COG0768	penicillin binding
CLAC_RS05180	COG0579	oxidoreductase
CLAC_RS05215	COG3022	response to hydroperoxide
CLAC_RS05220	COG0442	prolyl-tRNA aminoacylation
CLAC_RS05230	COG0779	Required for maturation of 30S ribosomal subunits
CLAC_RS05245	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLAC_RS05255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLAC_RS05260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CLAC_RS05275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLAC_RS05285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLAC_RS05290	COG1185	polyribonucleotide nucleotidyltransferase activity
CLAC_RS05295	COG2017	converts alpha-aldose to the beta-anomer
CLAC_RS05315	COG2814	Major facilitator Superfamily
CLAC_RS05320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLAC_RS05330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLAC_RS05335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLAC_RS05345	COG1674	ftsk spoiiie
CLAC_RS05365	COG1396	sequence-specific DNA binding
CLAC_RS05370	COG1842	Phage shock protein A
CLAC_RS05375	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLAC_RS05380	COG1122	ATPase activity
CLAC_RS05400	COG2137	regulation of response to DNA damage stimulus
CLAC_RS05405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLAC_RS05415	COG1196	nuclear chromosome segregation
CLAC_RS05425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLAC_RS05430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLAC_RS05450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLAC_RS05455	COG2233	PERMEase
CLAC_RS05465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLAC_RS05465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLAC_RS05465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLAC_RS05470	COG1105	Belongs to the carbohydrate kinase PfkB family
CLAC_RS05475	COG1349	DNA-binding transcription factor activity
CLAC_RS05480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLAC_RS05490	COG1643	Atp-dependent helicase
CLAC_RS05495	COG1054	Belongs to the UPF0176 family
CLAC_RS05500	COG4868	Belongs to the UPF0371 family
CLAC_RS05525	COG0450	alkyl hydroperoxide reductase
CLAC_RS05530	COG0583	DNA-binding transcription factor activity
CLAC_RS05555	COG1321	iron dependent repressor
CLAC_RS05570	COG2890	protein-(glutamine-N5) methyltransferase activity
CLAC_RS05595	COG0471	metal ion transport
CLAC_RS05625	COG0756	dUTP diphosphatase activity
CLAC_RS05635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLAC_RS05660	COG3253	May function as heme-dependent peroxidase
CLAC_RS05665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLAC_RS05680	COG1528	Iron-storage protein
CLAC_RS05730	COG2837	iron assimilation
CLAC_RS05745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLAC_RS05750	COG1560	Kdo2-lipid A biosynthetic process
CLAC_RS05755	COG0438	transferase activity, transferring glycosyl groups
CLAC_RS05765	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CLAC_RS05770	COG1946	Acyl-CoA thioesterase
CLAC_RS05780	COG0217	transcriptional regulatory protein
CLAC_RS05790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLAC_RS05795	COG0632	four-way junction helicase activity
CLAC_RS05810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLAC_RS05815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLAC_RS05825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLAC_RS05830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLAC_RS05845	COG1760	l-serine dehydratase
CLAC_RS05855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLAC_RS05875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLAC_RS05885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLAC_RS05895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLAC_RS05900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLAC_RS05905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLAC_RS05915	COG0006	proline dipeptidase activity
CLAC_RS05920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLAC_RS05925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLAC_RS05930	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLAC_RS05935	COG0540	Belongs to the ATCase OTCase family
CLAC_RS05940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLAC_RS05950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLAC_RS05965	COG0194	GDP metabolic process
CLAC_RS05970	COG1758	RNA polymerase activity
CLAC_RS05980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLAC_RS05985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLAC_RS05990	COG0242	peptide deformylase activity
CLAC_RS06025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLAC_RS06035	COG0322	excinuclease ABC activity
CLAC_RS06040	COG1660	Displays ATPase and GTPase activities
CLAC_RS06050	COG1481	regulation of sporulation
CLAC_RS06055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLAC_RS06060	COG0126	phosphoglycerate kinase activity
CLAC_RS06070	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CLAC_RS06075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLAC_RS06095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLAC_RS06105	COG0109	protoheme IX farnesyltransferase activity
CLAC_RS06120	COG1131	(ABC) transporter
CLAC_RS06145	COG0396	ATPase activity
CLAC_RS06155	COG0822	iron-sulfur transferase activity
CLAC_RS06160	COG2151	metal-sulfur cluster biosynthetic enzyme
CLAC_RS06165	COG0833	amino acid
CLAC_RS06175	COG0488	(ABC) transporter
CLAC_RS06215	COG3883	PFAM NLP P60 protein
CLAC_RS06215	COG0791	NLP P60 protein
CLAC_RS06220	COG0714	Associated with various cellular activities
CLAC_RS06230	COG2304	oxidoreductase activity
CLAC_RS06235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLAC_RS06285	COG0640	Transcriptional regulator
CLAC_RS06290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLAC_RS06305	COG0167	dihydroorotate dehydrogenase activity
CLAC_RS06315	COG0667	Aldo Keto reductase
CLAC_RS06325	COG0215	cysteine-tRNA ligase activity
CLAC_RS06335	COG1410	methionine synthase
CLAC_RS06335	COG0646	methionine synthase
CLAC_RS06345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLAC_RS06350	COG0140	phosphoribosyl-ATP diphosphatase activity
CLAC_RS06360	COG1027	Aspartate ammonia-lyase
CLAC_RS06365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLAC_RS06380	COG1222	aaa ATPase
CLAC_RS06415	COG0805	protein transport
CLAC_RS06425	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS06530	COG1253	flavin adenine dinucleotide binding
CLAC_RS06540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLAC_RS06550	COG3573	Dehydrogenase
CLAC_RS06570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLAC_RS06575	COG0352	thiamine-phosphate diphosphorylase activity
CLAC_RS06575	COG0351	phosphomethylpyrimidine kinase
CLAC_RS06575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLAC_RS06585	COG1253	flavin adenine dinucleotide binding
CLAC_RS06620	COG1716	ATPase activity
CLAC_RS06625	COG0653	protein targeting
CLAC_RS06630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLAC_RS06680	COG1160	GTP binding
CLAC_RS06695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLAC_RS06700	COG3104	oligopeptide transport
CLAC_RS06705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLAC_RS06710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLAC_RS06720	COG4974	Belongs to the 'phage' integrase family
CLAC_RS06725	COG0494	nUDIX hydrolase
CLAC_RS06730	COG0504	CTP synthase activity
CLAC_RS06735	COG1132	(ABC) transporter
CLAC_RS06740	COG1132	(ABC) transporter
CLAC_RS06740	COG2375	cellular response to nickel ion
CLAC_RS06755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAC_RS06760	COG4608	Belongs to the ABC transporter superfamily
CLAC_RS06765	COG2211	Major facilitator Superfamily
CLAC_RS06815	COG0497	DNA recombination
CLAC_RS06820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLAC_RS06835	COG0647	UMP catabolic process
CLAC_RS06845	COG0328	RNA-DNA hybrid ribonuclease activity
CLAC_RS06885	COG0531	amino acid
CLAC_RS06905	COG2094	Belongs to the DNA glycosylase MPG family
CLAC_RS06910	COG2835	tetraacyldisaccharide 4'-kinase activity
CLAC_RS06920	COG0137	argininosuccinate synthase activity
CLAC_RS06930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLAC_RS06935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLAC_RS06945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLAC_RS06950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLAC_RS06960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLAC_RS06960	COG0072	phenylalanine-tRNA ligase activity
CLAC_RS06965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLAC_RS06970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLAC_RS06975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLAC_RS06980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CLAC_RS07040	COG1131	(ABC) transporter
CLAC_RS07050	COG4585	Histidine kinase
CLAC_RS07055	COG2197	response regulator
CLAC_RS07070	COG0237	dephospho-CoA kinase activity
CLAC_RS07075	COG0435	Glutathione S-transferase
CLAC_RS07080	COG2826	transposase and inactivated derivatives, IS30 family
CLAC_RS07105	COG0539	negative regulation of cytoplasmic translation
CLAC_RS07355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLAC_RS07360	COG0765	amino acid transport
CLAC_RS07375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLAC_RS07390	COG1473	amidohydrolase
CLAC_RS07395	COG0469	pyruvate kinase activity
CLAC_RS07405	COG0159	tryptophan synthase activity
CLAC_RS07415	COG0134	indole-3-glycerol-phosphate synthase activity
CLAC_RS07425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLAC_RS07430	COG0657	acetylesterase activity
CLAC_RS07440	COG0107	imidazoleglycerol-phosphate synthase activity
CLAC_RS07445	COG0483	inositol monophosphate 1-phosphatase activity
CLAC_RS07450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLAC_RS07455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLAC_RS07475	COG0131	Imidazoleglycerol-phosphate dehydratase
CLAC_RS07485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLAC_RS07515	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLAC_RS07535	COG1309	transcriptional regulator
CLAC_RS07540	COG2056	Na+-H+ antiporter family
CLAC_RS07600	COG1739	Uncharacterized protein family UPF0029
CLAC_RS07615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLAC_RS07650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLAC_RS07665	COG0252	asparaginase activity
CLAC_RS07670	COG0110	maltose O-acetyltransferase activity
CLAC_RS07675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLAC_RS07680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLAC_RS07685	COG3599	regulation of cell shape
CLAC_RS07700	COG1496	oxidoreductase activity
CLAC_RS07705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLAC_RS07715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLAC_RS07720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLAC_RS07730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLAC_RS07735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLAC_RS07745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLAC_RS07750	COG0768	penicillin binding
CLAC_RS07765	COG2001	Belongs to the MraZ family
CLAC_RS07780	COG0456	acetyltransferase
CLAC_RS07795	COG0142	geranyltranstransferase activity
CLAC_RS07825	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CLAC_RS07845	COG0438	transferase activity, transferring glycosyl groups
CLAC_RS07855	COG0791	NLP P60 protein
CLAC_RS07865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLAC_RS07880	COG0723	plastoquinol--plastocyanin reductase activity
CLAC_RS07890	COG0488	(ABC) transporter
CLAC_RS07925	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CLAC_RS07930	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLAC_RS07940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLAC_RS07945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLAC_RS07950	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLAC_RS07960	COG0321	lipoyl(octanoyl) transferase activity
CLAC_RS07975	COG2985	domain, Protein
CLAC_RS07975	COG0569	domain protein
CLAC_RS07985	COG0174	glutamine synthetase
CLAC_RS07990	COG0477	Major facilitator Superfamily
CLAC_RS08020	COG2818	Glycosylase
CLAC_RS08035	COG2190	(PTS) system
CLAC_RS08035	COG1263	PTS System
CLAC_RS08035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLAC_RS08040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLAC_RS08045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLAC_RS08055	COG1114	Component of the transport system for branched-chain amino acids
CLAC_RS08065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLAC_RS08085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CLAC_RS08090	COG0174	glutamine synthetase
CLAC_RS08095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLAC_RS08105	COG2259	Doxx family
CLAC_RS08120	COG0557	exoribonuclease II activity
CLAC_RS08145	COG0546	phosphoglycolate phosphatase activity
CLAC_RS08180	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLAC_RS08200	COG1823	symporter activity
CLAC_RS08215	COG1435	thymidine kinase activity
CLAC_RS08220	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CLAC_RS08220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLAC_RS08250	COG3842	ATPase activity
CLAC_RS08255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLAC_RS08265	COG1136	(ABC) transporter
CLAC_RS08275	COG2197	response regulator
CLAC_RS08280	COG1012	belongs to the aldehyde dehydrogenase family
CLAC_RS08325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLAC_RS08350	COG0423	glycine-tRNA ligase activity
CLAC_RS08360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLAC_RS08365	COG1381	Involved in DNA repair and RecF pathway recombination
CLAC_RS08380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLAC_RS08385	COG1702	phosphate starvation-inducible protein PhoH
CLAC_RS08400	COG1420	regulation of RNA biosynthetic process
CLAC_RS08415	COG1022	Amp-dependent synthetase and ligase
CLAC_RS08430	COG0339	signal peptide processing
CLAC_RS08440	COG3402	PFAM membrane-flanked domain
CLAC_RS08450	COG0366	Alpha amylase catalytic
CLAC_RS08460	COG1132	(ABC) transporter
CLAC_RS08470	COG0277	FAD linked oxidase domain protein
CLAC_RS08485	COG0671	phosphoesterase, PA-phosphatase related
CLAC_RS08505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLAC_RS08510	COG1335	isochorismatase
CLAC_RS08515	COG2354	Protein conserved in bacteria
CLAC_RS08520	COG3012	SEC-C Motif Domain Protein
CLAC_RS08530	COG1070	Carbohydrate kinase
CLAC_RS08550	COG0277	FAD linked oxidase domain protein
CLAC_RS08555	COG2066	Belongs to the glutaminase family
CLAC_RS08600	COG0012	GTP binding
CLAC_RS08605	COG0628	permease
CLAC_RS08615	COG1570	exodeoxyribonuclease VII activity
CLAC_RS08630	COG1494	fructose-1,6-bisphosphatase
CLAC_RS08635	COG0114	fumarate hydratase activity
CLAC_RS08640	COG1090	epimerase
CLAC_RS08645	COG0415	Belongs to the DNA photolyase family
CLAC_RS08650	COG2409	Drug exporters of the RND superfamily
CLAC_RS08655	COG1309	transcriptional regulator
CLAC_RS08680	COG2267	carboxylic ester hydrolase activity
CLAC_RS08685	COG1960	acyl-CoA dehydrogenase activity
CLAC_RS08690	COG0733	neurotransmitter:sodium symporter activity
CLAC_RS08700	COG1024	Enoyl-CoA hydratase
CLAC_RS08730	COG1072	(Pantothenic acid kinase))
CLAC_RS08740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLAC_RS08750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CLAC_RS08760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLAC_RS08780	COG1012	belongs to the aldehyde dehydrogenase family
CLAC_RS08805	COG0148	phosphopyruvate hydratase activity
CLAC_RS08815	COG3956	TIGRFAM MazG family protein
CLAC_RS08835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLAC_RS08840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLAC_RS08845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLAC_RS08850	COG1120	ATPase activity
CLAC_RS08855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS08860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS08865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CLAC_RS08870	COG0193	aminoacyl-tRNA hydrolase activity
CLAC_RS08885	COG0561	phosphatase activity
CLAC_RS08890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLAC_RS08910	COG1024	Enoyl-CoA hydratase
CLAC_RS08915	COG2326	polyphosphate kinase activity
CLAC_RS08920	COG2177	Part of the ABC transporter FtsEX involved in
CLAC_RS08925	COG2884	Cell division ATP-binding protein ftsE
CLAC_RS08935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLAC_RS08940	COG0483	inositol monophosphate 1-phosphatase activity
CLAC_RS08945	COG0483	inositol monophosphate 1-phosphatase activity
CLAC_RS08970	COG1937	Protein conserved in bacteria
CLAC_RS09065	COG1192	Involved in chromosome partitioning
CLAC_RS09095	COG1132	(ABC) transporter
CLAC_RS09105	COG2963	transposase activity
CLAC_RS09155	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLAC_RS09160	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CLAC_RS09180	COG0488	(ABC) transporter
CLAC_RS09185	COG0494	nUDIX hydrolase
CLAC_RS09190	COG2755	lipolytic protein G-D-S-L family
CLAC_RS09190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CLAC_RS09200	COG3583	domain protein
CLAC_RS09205	COG0084	hydrolase, TatD family'
CLAC_RS09215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLAC_RS09220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLAC_RS09230	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CLAC_RS09240	COG2259	Doxx family
CLAC_RS09260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLAC_RS09265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLAC_RS09285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLAC_RS09290	COG2205	protein histidine kinase activity
CLAC_RS09295	COG0745	RESPONSE REGULATOR receiver
CLAC_RS09305	COG0254	rRNA binding
CLAC_RS09310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLAC_RS09315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLAC_RS09320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLAC_RS09340	COG0069	glutamate synthase activity
CLAC_RS09365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLAC_RS09370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLAC_RS09385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS09400	COG1476	TRANSCRIPTIONal
CLAC_RS09410	COG0189	ligase activity
CLAC_RS09415	COG2897	thiosulfate sulfurtransferase activity
CLAC_RS09420	COG4770	biotin carboxylase activity
CLAC_RS09680	COG4974	Belongs to the 'phage' integrase family
CLAC_RS09705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLAC_RS09710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLAC_RS09720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLAC_RS09725	COG1024	Enoyl-CoA hydratase
CLAC_RS09730	COG0656	L-ascorbic acid biosynthetic process
CLAC_RS09745	COG4152	abc transporter atp-binding protein
CLAC_RS09750	COG1668	transmembrane transport
CLAC_RS09755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLAC_RS09775	COG0545	Peptidyl-prolyl cis-trans isomerase
CLAC_RS09780	COG0372	Belongs to the citrate synthase family
CLAC_RS09800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLAC_RS09805	COG2252	PERMEase
CLAC_RS09825	COG1278	Cold shock
CLAC_RS09830	COG1652	LysM domain
CLAC_RS09875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLAC_RS09885	COG2197	response regulator
CLAC_RS09890	COG1122	ATPase activity
CLAC_RS09900	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CLAC_RS09905	COG0310	cobalt ion transport
CLAC_RS09915	COG1045	serine acetyltransferase
CLAC_RS09970	COG1271	oxidase subunit
CLAC_RS09975	COG1294	oxidase, subunit
CLAC_RS09980	COG4988	ABC transporter
CLAC_RS09985	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLAC_RS10000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLAC_RS10020	COG0456	acetyltransferase
CLAC_RS10030	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CLAC_RS10050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLAC_RS10065	COG1607	acyl-coa hydrolase
CLAC_RS10075	COG1120	ATPase activity
CLAC_RS10090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLAC_RS10100	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLAC_RS10110	COG0386	Belongs to the glutathione peroxidase family
CLAC_RS10120	COG0778	Nitroreductase
CLAC_RS10145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CLAC_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
CLAC_RS10165	COG0431	NADPH-dependent FMN reductase
CLAC_RS10230	COG1131	(ABC) transporter
CLAC_RS10235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLAC_RS10245	COG2814	Major facilitator Superfamily
CLAC_RS10250	COG1126	abc transporter atp-binding protein
CLAC_RS10260	COG0765	amino acid transport
CLAC_RS10265	COG0765	amino acid transport
CLAC_RS10270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLAC_RS10290	COG2022	thiamine diphosphate biosynthetic process
CLAC_RS10300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLAC_RS10300	COG2022	thiamine diphosphate biosynthetic process
CLAC_RS10305	COG0352	thiamine-phosphate diphosphorylase activity
CLAC_RS10310	COG0569	domain protein
CLAC_RS10315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLAC_RS10325	COG0133	tryptophan synthase activity
CLAC_RS10355	COG0436	Aminotransferase
CLAC_RS10360	COG0151	Belongs to the GarS family
CLAC_RS10365	COG0537	adenosine 5'-monophosphoramidase activity
CLAC_RS10410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLAC_RS10415	COG1609	Transcriptional regulator
CLAC_RS10425	COG1121	(ABC) transporter
CLAC_RS10430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLAC_RS10435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLAC_RS10450	COG2847	Copper chaperone PCu(A)C
CLAC_RS10470	COG1194	a g-specific adenine glycosylase
CLAC_RS10485	COG0542	response to heat
CLAC_RS10495	COG1595	DNA-templated transcription, initiation
CLAC_RS10510	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS10530	COG1960	acyl-CoA dehydrogenase activity
CLAC_RS10535	COG1960	acyl-CoA dehydrogenase activity
CLAC_RS10555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLAC_RS10565	COG3766	membrane
CLAC_RS10590	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CLAC_RS10595	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLAC_RS10620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLAC_RS10630	COG0302	gtp cyclohydrolase
CLAC_RS10635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLAC_RS10645	COG0037	tRNA processing
CLAC_RS10650	COG0154	amidase activity
CLAC_RS10655	COG2027	D-alanyl-D-alanine carboxypeptidase
CLAC_RS10660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLAC_RS10675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLAC_RS10685	COG0318	PFAM AMP-dependent synthetase and ligase
CLAC_RS10690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLAC_RS10695	COG2837	iron assimilation
CLAC_RS10700	COG2326	polyphosphate kinase activity
CLAC_RS10720	COG2111	Na H antiporter
CLAC_RS10720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLAC_RS10725	COG1006	Multisubunit Na H antiporter MnhC subunit
CLAC_RS10730	COG0651	ATP synthesis coupled electron transport
CLAC_RS10740	COG2212	antiporter activity
CLAC_RS10745	COG1320	monovalent cation:proton antiporter activity
CLAC_RS10770	COG0242	peptide deformylase activity
CLAC_RS10810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLAC_RS10830	COG0280	phosphate acetyltransferase
CLAC_RS10845	COG2895	sulfate adenylyltransferase (ATP) activity
CLAC_RS10860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLAC_RS10865	COG0730	response to heat
CLAC_RS10875	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CLAC_RS10900	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLAC_RS10915	COG0431	NADPH-dependent FMN reductase
CLAC_RS10920	COG4129	membrane
CLAC_RS10945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLAC_RS10970	COG0542	response to heat
CLAC_RS10975	COG3588	fructose-bisphosphate aldolase
CLAC_RS10985	COG0586	Pfam SNARE associated Golgi protein
CLAC_RS10995	COG2860	membrane
CLAC_RS11000	COG1113	amino acid transport
CLAC_RS11005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLAC_RS11010	COG1960	acyl-CoA dehydrogenase activity
CLAC_RS11015	COG1012	belongs to the aldehyde dehydrogenase family
CLAC_RS11020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLAC_RS11045	COG0789	Transcriptional regulator
CLAC_RS11050	COG0484	heat shock protein binding
CLAC_RS11060	COG0443	Heat shock 70 kDa protein
CLAC_RS11085	COG2271	Major facilitator Superfamily
CLAC_RS11090	COG0666	response to abiotic stimulus
CLAC_RS11115	COG0019	diaminopimelate decarboxylase activity
CLAC_RS11125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLAC_RS11130	COG1024	Enoyl-CoA hydratase
CLAC_RS11135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLAC_RS11145	COG1960	acyl-CoA dehydrogenase activity
CLAC_RS11155	COG0123	including yeast histone deacetylase and acetoin utilization protein
CLAC_RS11180	COG0814	amino acid
CLAC_RS11190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLAC_RS11200	COG0247	lactate metabolic process
CLAC_RS11200	COG2181	nitrate reductase activity
CLAC_RS11210	COG2197	response regulator
CLAC_RS11235	COG0431	NADPH-dependent FMN reductase
CLAC_RS11265	COG1129	ABC transporter
CLAC_RS11270	COG2375	cellular response to nickel ion
CLAC_RS11270	COG1132	(ABC) transporter
CLAC_RS11275	COG1132	(ABC) transporter
CLAC_RS11285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CLAC_RS11295	COG1174	glycine betaine transport
CLAC_RS11305	COG0517	IMP dehydrogenase activity
CLAC_RS11305	COG1125	glycine betaine transport
CLAC_RS11320	COG2197	response regulator
CLAC_RS11330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLAC_RS11335	COG2807	transmembrane transport
CLAC_RS11365	COG4981	capsule polysaccharide biosynthetic process
CLAC_RS11365	COG4981	capsule polysaccharide biosynthetic process
CLAC_RS11385	COG0438	transferase activity, transferring glycosyl groups
CLAC_RS11405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS11410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS11415	COG1120	ATPase activity
CLAC_RS11430	COG0183	Belongs to the thiolase family
CLAC_RS11435	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLAC_RS11435	COG1024	Enoyl-CoA hydratase
CLAC_RS11445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLAC_RS11455	COG0601	transmembrane transport
CLAC_RS11460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAC_RS11480	COG2391	methyltransferase activity
CLAC_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
CLAC_RS11500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLAC_RS11505	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLAC_RS11515	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CLAC_RS11535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLAC_RS11555	COG3104	oligopeptide transport
CLAC_RS11560	COG3830	Belongs to the UPF0237 family
CLAC_RS11565	COG2848	UPF0210 protein
CLAC_RS11570	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CLAC_RS11590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLAC_RS11595	COG0671	phosphoesterase, PA-phosphatase related
CLAC_RS11600	COG1216	Glycosyl transferase, family 2
CLAC_RS11605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLAC_RS11610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS11615	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAC_RS11620	COG1120	ATPase activity
CLAC_RS11630	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CLAC_RS11645	COG2963	transposase activity
CLAC_RS11735	COG0561	phosphatase activity
CLAC_RS11745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLAC_RS11750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLAC_RS11755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLAC_RS11765	COG1280	lysine exporter protein (LysE YggA)
CLAC_RS11790	COG0077	Prephenate dehydratase
CLAC_RS11805	COG1316	TRANSCRIPTIONal
CLAC_RS11820	COG0469	pyruvate kinase activity
CLAC_RS11835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLAC_RS11865	COG0706	membrane insertase activity
CLAC_RS11890	COG0577	efflux transmembrane transporter activity
CLAC_RS11890	COG1136	(ABC) transporter
CLAC_RS11940	COG1842	Phage shock protein A
CLAC_RS11955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLAC_RS11970	COG0305	Participates in initiation and elongation during chromosome replication
CLAC_RS11975	COG0359	binds to the 23S rRNA
CLAC_RS11980	COG0629	single-stranded DNA binding
CLAC_RS11985	COG0360	Binds together with S18 to 16S ribosomal RNA
CLAC_RS11995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLAC_RS12000	COG1260	myo-inositol-1-phosphate synthase
CLAC_RS12020	COG0495	leucyl-tRNA aminoacylation
CLAC_RS12040	COG0477	Major facilitator Superfamily
CLAC_RS12055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CLAC_RS12060	COG1678	Uncharacterized ACR, COG1678
CLAC_RS12095	COG3118	belongs to the thioredoxin family
CLAC_RS12100	COG3409	Peptidoglycan-binding domain 1 protein
CLAC_RS12100	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLAC_RS12115	COG1192	Involved in chromosome partitioning
CLAC_RS12135	COG0230	Belongs to the bacterial ribosomal protein bL34 family