locus-tag	class	description
Csp1_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Csp1_RS00015	COG0592	DNA-directed DNA polymerase activity
Csp1_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Csp1_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Csp1_RS00030	COG0187	DNA topoisomerase II activity
Csp1_RS00050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Csp1_RS00055	COG4521	taurine ABC transporter
Csp1_RS00060	COG1116	anion transmembrane transporter activity
Csp1_RS00075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Csp1_RS00155	COG2910	NAD(P)H-binding
Csp1_RS00165	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS00170	COG1609	Transcriptional regulator
Csp1_RS00185	COG0252	asparaginase activity
Csp1_RS00195	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS00245	COG1335	isochorismatase
Csp1_RS00250	COG3842	ATPase activity
Csp1_RS00270	COG1175	transmembrane transport
Csp1_RS00275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Csp1_RS00280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS00285	COG2264	protein methyltransferase activity
Csp1_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS00295	COG0702	epimerase
Csp1_RS00315	COG0561	phosphatase activity
Csp1_RS00400	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS00410	COG1929	Belongs to the glycerate kinase type-1 family
Csp1_RS00420	COG2205	protein histidine kinase activity
Csp1_RS00425	COG0745	RESPONSE REGULATOR receiver
Csp1_RS00445	COG0300	oxidoreductase activity
Csp1_RS00455	COG2815	serine threonine protein kinase
Csp1_RS00455	COG0515	serine threonine protein kinase
Csp1_RS00465	COG0768	penicillin binding
Csp1_RS00480	COG1716	ATPase activity
Csp1_RS00485	COG1716	ATPase activity
Csp1_RS00510	COG0604	alcohol dehydrogenase
Csp1_RS00520	COG0667	Aldo Keto reductase
Csp1_RS00535	COG2030	dehydratase
Csp1_RS00545	COG1902	pentaerythritol trinitrate reductase activity
Csp1_RS00555	COG3328	transposase activity
Csp1_RS00570	COG0508	dehydrogenase complex catalyzes the overall conversion of
Csp1_RS00570	COG0596	Alpha beta hydrolase
Csp1_RS00640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS00650	COG3842	ATPase activity
Csp1_RS00670	COG0789	Transcriptional regulator
Csp1_RS00690	COG0640	Transcriptional regulator
Csp1_RS00720	COG1278	Cold shock
Csp1_RS00725	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS00730	COG0577	efflux transmembrane transporter activity
Csp1_RS00730	COG1136	(ABC) transporter
Csp1_RS00750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Csp1_RS00750	COG2755	lipolytic protein G-D-S-L family
Csp1_RS00770	COG4592	Periplasmic binding protein
Csp1_RS00785	COG0488	(ABC) transporter
Csp1_RS00800	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS00810	COG0667	Aldo Keto reductase
Csp1_RS00820	COG1253	flavin adenine dinucleotide binding
Csp1_RS00830	COG0783	Belongs to the Dps family
Csp1_RS00835	COG1051	belongs to the nudix hydrolase family
Csp1_RS00850	COG1301	dicarboxylic acid transport
Csp1_RS00890	COG1119	ATPase activity
Csp1_RS00895	COG0681	Belongs to the peptidase S26 family
Csp1_RS00900	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Csp1_RS00910	COG1802	Transcriptional regulator
Csp1_RS00930	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS01010	COG2094	Belongs to the DNA glycosylase MPG family
Csp1_RS01020	COG0747	negative chemotaxis
Csp1_RS01030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Csp1_RS01050	COG0667	Aldo Keto reductase
Csp1_RS01085	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS01095	COG1132	(ABC) transporter
Csp1_RS01100	COG4988	ABC transporter
Csp1_RS01105	COG1294	oxidase, subunit
Csp1_RS01110	COG1271	oxidase subunit
Csp1_RS01115	COG1937	Protein conserved in bacteria
Csp1_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Csp1_RS01155	COG0583	DNA-binding transcription factor activity
Csp1_RS01160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Csp1_RS01165	COG0393	Putative heavy-metal-binding
Csp1_RS01175	COG0494	nUDIX hydrolase
Csp1_RS01190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Csp1_RS01205	COG0477	Major facilitator Superfamily
Csp1_RS01215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Csp1_RS01230	COG0154	amidase activity
Csp1_RS01235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Csp1_RS01245	COG1090	epimerase
Csp1_RS01250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Csp1_RS01270	COG0667	Aldo Keto reductase
Csp1_RS01280	COG0601	transmembrane transport
Csp1_RS01300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS01305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS01325	COG0583	DNA-binding transcription factor activity
Csp1_RS01330	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS01335	COG2072	flavoprotein involved in K transport
Csp1_RS01380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Csp1_RS01390	COG1802	Transcriptional regulator
Csp1_RS01405	COG0596	Alpha beta hydrolase
Csp1_RS01410	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS01420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS01430	COG0402	S-adenosylhomocysteine deaminase activity
Csp1_RS01440	COG2351	hydroxyisourate hydrolase activity
Csp1_RS01450	COG0531	amino acid
Csp1_RS01460	COG0740	serine-type endopeptidase activity
Csp1_RS01465	COG0740	serine-type endopeptidase activity
Csp1_RS01470	COG0402	S-adenosylhomocysteine deaminase activity
Csp1_RS01475	COG0259	pyridoxamine-phosphate oxidase activity
Csp1_RS01510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Csp1_RS01530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Csp1_RS01550	COG2072	flavoprotein involved in K transport
Csp1_RS01555	COG4266	Belongs to the allantoicase family
Csp1_RS01560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Csp1_RS01570	COG1953	Uracil, thiamine, allantoin
Csp1_RS01580	COG0477	Major facilitator Superfamily
Csp1_RS01585	COG1309	transcriptional regulator
Csp1_RS01590	COG0492	ferredoxin-NADP+ reductase activity
Csp1_RS01595	COG0477	Major facilitator Superfamily
Csp1_RS01630	COG1120	ATPase activity
Csp1_RS01635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Csp1_RS01640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS01655	COG0831	urea catabolic process
Csp1_RS01665	COG0831	urea catabolic process
Csp1_RS01665	COG0832	Belongs to the urease beta subunit family
Csp1_RS01670	COG0804	urea catabolic process
Csp1_RS01675	COG0830	nickel cation binding
Csp1_RS01680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Csp1_RS01685	COG0829	nickel cation binding
Csp1_RS01715	COG2801	Transposase and inactivated derivatives
Csp1_RS01730	COG2070	2-Nitropropane dioxygenase
Csp1_RS01735	COG3189	MarR family transcriptional regulator
Csp1_RS01745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Csp1_RS01755	COG1643	Atp-dependent helicase
Csp1_RS01765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Csp1_RS01780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Csp1_RS01810	COG3328	transposase activity
Csp1_RS01865	COG2197	response regulator
Csp1_RS01870	COG4585	Histidine kinase
Csp1_RS01895	COG0287	Prephenate dehydrogenase
Csp1_RS01930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Csp1_RS01930	COG2755	lipolytic protein G-D-S-L family
Csp1_RS01935	COG2409	Drug exporters of the RND superfamily
Csp1_RS01940	COG0343	queuine tRNA-ribosyltransferase activity
Csp1_RS01950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Csp1_RS01965	COG1024	Enoyl-CoA hydratase
Csp1_RS02000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS02005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS02010	COG1120	ATPase activity
Csp1_RS02020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Csp1_RS02020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Csp1_RS02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Csp1_RS02060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Csp1_RS02075	COG4770	biotin carboxylase activity
Csp1_RS02080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Csp1_RS02085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Csp1_RS02095	COG0180	Tryptophanyl-tRNA synthetase
Csp1_RS02100	COG1492	cobalamin metabolic process
Csp1_RS02105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Csp1_RS02135	COG0697	spore germination
Csp1_RS02140	COG4592	Periplasmic binding protein
Csp1_RS02145	COG4592	Periplasmic binding protein
Csp1_RS02155	COG0527	aspartate kinase activity
Csp1_RS02165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Csp1_RS02170	COG0446	pyridine nucleotide-disulphide oxidoreductase
Csp1_RS02175	COG0346	lactoylglutathione lyase activity
Csp1_RS02205	COG0651	ATP synthesis coupled electron transport
Csp1_RS02215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Csp1_RS02215	COG2111	Na H antiporter
Csp1_RS02240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Csp1_RS02255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Csp1_RS02260	COG0019	diaminopimelate decarboxylase activity
Csp1_RS02265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Csp1_RS02270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Csp1_RS02280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Csp1_RS02285	COG0494	nUDIX hydrolase
Csp1_RS02340	COG1205	dead DEAH box helicase
Csp1_RS02340	COG1111	helicase
Csp1_RS02360	COG1754	DNA topoisomerase type I activity
Csp1_RS02360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Csp1_RS02370	COG0671	phosphoesterase, PA-phosphatase related
Csp1_RS02430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Csp1_RS02440	COG2224	Isocitrate lyase
Csp1_RS02445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Csp1_RS02465	COG1053	succinate dehydrogenase
Csp1_RS02470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Csp1_RS02480	COG2733	membrane
Csp1_RS02490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Csp1_RS02510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Csp1_RS02515	COG0438	transferase activity, transferring glycosyl groups
Csp1_RS02525	COG0588	phosphoglycerate mutase activity
Csp1_RS02530	COG5002	protein histidine kinase activity
Csp1_RS02535	COG0745	RESPONSE REGULATOR receiver
Csp1_RS02555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Csp1_RS02575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Csp1_RS02585	COG1648	precorrin-2 dehydrogenase activity
Csp1_RS02585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Csp1_RS02590	COG0113	porphobilinogen synthase activity
Csp1_RS02605	COG2217	Heavy metal translocating P-type atpase
Csp1_RS02610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Csp1_RS02620	COG0406	alpha-ribazole phosphatase activity
Csp1_RS02630	COG0785	Cytochrome C biogenesis protein
Csp1_RS02640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Csp1_RS02655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Csp1_RS02695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Csp1_RS02700	COG4948	Mandelate Racemase Muconate Lactonizing
Csp1_RS02705	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Csp1_RS02715	COG2226	methyltransferase
Csp1_RS02720	COG0644	oxidoreductase
Csp1_RS02725	COG0142	geranyltranstransferase activity
Csp1_RS02760	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Csp1_RS02765	COG0081	regulation of translation
Csp1_RS02775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Csp1_RS02790	COG0085	RNA polymerase activity
Csp1_RS02795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Csp1_RS02805	COG0049	tRNA binding
Csp1_RS02815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Csp1_RS02845	COG1302	Protein conserved in bacteria
Csp1_RS02850	COG0051	transcription antitermination factor activity, RNA binding
Csp1_RS02860	COG0088	Forms part of the polypeptide exit tunnel
Csp1_RS02865	COG0089	rRNA binding
Csp1_RS02870	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Csp1_RS02875	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Csp1_RS02880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Csp1_RS02885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Csp1_RS02890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Csp1_RS02895	COG0255	Belongs to the universal ribosomal protein uL29 family
Csp1_RS02900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Csp1_RS02905	COG1021	2,3-dihydroxybenzoate-AMP ligase
Csp1_RS02920	COG1535	isochorismatase
Csp1_RS02920	COG3433	isochorismatase activity
Csp1_RS02945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Csp1_RS02985	COG1120	ATPase activity
Csp1_RS02990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS02995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS03000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Csp1_RS03005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Csp1_RS03010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Csp1_RS03025	COG1648	precorrin-2 dehydrogenase activity
Csp1_RS03025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Csp1_RS03035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Csp1_RS03035	COG2146	nitrite reductase [NAD(P)H] activity
Csp1_RS03040	COG0243	molybdopterin cofactor binding
Csp1_RS03045	COG2223	nitrite transmembrane transporter activity
Csp1_RS03065	COG4149	molybdate abc transporter
Csp1_RS03085	COG0303	'Molybdopterin
Csp1_RS03110	COG0314	molybdopterin synthase activity
Csp1_RS03120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Csp1_RS03155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Csp1_RS03160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Csp1_RS03165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Csp1_RS03170	COG1841	ribosomal large subunit assembly
Csp1_RS03180	COG0201	protein transport
Csp1_RS03185	COG0563	adenylate kinase activity
Csp1_RS03195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Csp1_RS03205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Csp1_RS03215	COG0202	RNA polymerase activity
Csp1_RS03220	COG0203	ribosomal protein L17
Csp1_RS03230	COG0101	tRNA pseudouridine synthase activity
Csp1_RS03260	COG1404	Belongs to the peptidase S8 family
Csp1_RS03270	COG1674	ftsk spoiiie
Csp1_RS03295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Csp1_RS03305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Csp1_RS03340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Csp1_RS03355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Csp1_RS03360	COG0459	protein refolding
Csp1_RS03390	COG0516	GMP reductase activity
Csp1_RS03420	COG2011	ABC-type metal ion transport system permease component
Csp1_RS03425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Csp1_RS03430	COG1464	Belongs to the NlpA lipoprotein family
Csp1_RS03435	COG1396	sequence-specific DNA binding
Csp1_RS03440	COG0587	DNA-directed DNA polymerase activity
Csp1_RS03465	COG3579	cysteine-type endopeptidase activity
Csp1_RS03470	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Csp1_RS03470	COG2308	Evidence 4 Homologs of previously reported genes of
Csp1_RS03480	COG1362	aminopeptidase activity
Csp1_RS03485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Csp1_RS03490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Csp1_RS03510	COG4208	sulfate ABC transporter
Csp1_RS03515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Csp1_RS03525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Csp1_RS03530	COG2873	o-acetylhomoserine
Csp1_RS03545	COG2838	Isocitrate dehydrogenase
Csp1_RS03550	COG2814	Major facilitator Superfamily
Csp1_RS03565	COG0583	DNA-binding transcription factor activity
Csp1_RS03570	COG0180	Tryptophanyl-tRNA synthetase
Csp1_RS03575	COG1295	ribonuclease BN
Csp1_RS03580	COG1686	Belongs to the peptidase S11 family
Csp1_RS03585	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Csp1_RS03595	COG1132	(ABC) transporter
Csp1_RS03625	COG1172	Belongs to the binding-protein-dependent transport system permease family
Csp1_RS03640	COG2815	serine threonine protein kinase
Csp1_RS03640	COG0515	serine threonine protein kinase
Csp1_RS03670	COG0741	lytic transglycosylase activity
Csp1_RS03670	COG0791	NLP P60 protein
Csp1_RS03690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Csp1_RS03700	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Csp1_RS03700	COG1473	amidohydrolase
Csp1_RS03710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Csp1_RS03715	COG4770	biotin carboxylase activity
Csp1_RS03720	COG2897	thiosulfate sulfurtransferase activity
Csp1_RS03725	COG0424	maF-like protein
Csp1_RS03735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Csp1_RS03740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Csp1_RS03740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Csp1_RS03785	COG3842	ATPase activity
Csp1_RS03790	COG4585	Histidine kinase
Csp1_RS03795	COG2197	response regulator
Csp1_RS03820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Csp1_RS03820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Csp1_RS03825	COG1316	TRANSCRIPTIONal
Csp1_RS03830	COG1091	dTDP-4-dehydrorhamnose reductase activity
Csp1_RS03840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Csp1_RS03865	COG1482	cell wall glycoprotein biosynthetic process
Csp1_RS03880	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Csp1_RS03890	COG0745	RESPONSE REGULATOR receiver
Csp1_RS03895	COG5000	phosphorelay sensor kinase activity
Csp1_RS03895	COG5002	protein histidine kinase activity
Csp1_RS03900	COG5401	PFAM Sporulation and spore germination
Csp1_RS03910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Csp1_RS03915	COG0653	protein targeting
Csp1_RS03925	COG1011	Hydrolase
Csp1_RS03935	COG1162	GTPase activity
Csp1_RS03940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Csp1_RS03975	COG0513	Belongs to the DEAD box helicase family
Csp1_RS04035	COG3480	Lon protease (S16) C-terminal proteolytic domain
Csp1_RS04045	COG1615	UPF0182 protein
Csp1_RS04055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Csp1_RS04075	COG1126	abc transporter atp-binding protein
Csp1_RS04090	COG0300	oxidoreductase activity
Csp1_RS04095	COG0693	protein deglycase activity
Csp1_RS04105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Csp1_RS04105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Csp1_RS04105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Csp1_RS04110	COG1105	Belongs to the carbohydrate kinase PfkB family
Csp1_RS04115	COG1349	DNA-binding transcription factor activity
Csp1_RS04165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Csp1_RS04175	COG1960	acyl-CoA dehydrogenase activity
Csp1_RS04190	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS04195	COG0183	Belongs to the thiolase family
Csp1_RS04200	COG0679	Auxin Efflux Carrier
Csp1_RS04215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Csp1_RS04220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Csp1_RS04225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Csp1_RS04230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Csp1_RS04235	COG0254	rRNA binding
Csp1_RS04245	COG0745	RESPONSE REGULATOR receiver
Csp1_RS04250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Csp1_RS04255	COG0521	Mo-molybdopterin cofactor biosynthetic process
Csp1_RS04270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Csp1_RS04290	COG2259	Doxx family
Csp1_RS04300	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
Csp1_RS04310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Csp1_RS04320	COG0084	hydrolase, TatD family'
Csp1_RS04325	COG3583	domain protein
Csp1_RS04330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Csp1_RS04335	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Csp1_RS04340	COG0488	(ABC) transporter
Csp1_RS04365	COG4638	Rieske (2fe-2S)
Csp1_RS04370	COG0583	DNA-binding transcription factor activity
Csp1_RS04380	COG1414	Transcriptional regulator
Csp1_RS04385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Csp1_RS04390	COG2326	polyphosphate kinase activity
Csp1_RS04400	COG1024	Enoyl-CoA hydratase
Csp1_RS04425	COG2409	Drug exporters of the RND superfamily
Csp1_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS04445	COG3433	isochorismatase activity
Csp1_RS04445	COG1535	isochorismatase
Csp1_RS04450	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Csp1_RS04465	COG2376	Dihydroxyacetone kinase
Csp1_RS04470	COG0193	aminoacyl-tRNA hydrolase activity
Csp1_RS04475	COG0193	aminoacyl-tRNA hydrolase activity
Csp1_RS04480	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Csp1_RS04485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Csp1_RS04490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Csp1_RS04505	COG3956	TIGRFAM MazG family protein
Csp1_RS04510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Csp1_RS04515	COG1121	(ABC) transporter
Csp1_RS04520	COG0803	Belongs to the bacterial solute-binding protein 9 family
Csp1_RS04535	COG0148	phosphopyruvate hydratase activity
Csp1_RS04560	COG0477	Major facilitator Superfamily
Csp1_RS04595	COG3425	synthase
Csp1_RS04605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Csp1_RS04610	COG0431	NADPH-dependent FMN reductase
Csp1_RS04640	COG0640	Transcriptional regulator
Csp1_RS04645	COG0604	alcohol dehydrogenase
Csp1_RS04650	COG1733	regulation of RNA biosynthetic process
Csp1_RS04670	COG4221	oxidoreductase activity
Csp1_RS04675	COG2226	methyltransferase
Csp1_RS04675	COG1073	alpha beta
Csp1_RS04680	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS04690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Csp1_RS04700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Csp1_RS04715	COG1072	(Pantothenic acid kinase))
Csp1_RS04720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Csp1_RS04725	COG1335	isochorismatase
Csp1_RS04730	COG1024	Enoyl-CoA hydratase
Csp1_RS04735	COG1960	acyl-CoA dehydrogenase activity
Csp1_RS04750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Csp1_RS04765	COG1309	transcriptional regulator
Csp1_RS04770	COG0328	RNA-DNA hybrid ribonuclease activity
Csp1_RS04780	COG0114	fumarate hydratase activity
Csp1_RS04785	COG1494	fructose-1,6-bisphosphatase
Csp1_RS04795	COG1722	exodeoxyribonuclease VII activity
Csp1_RS04800	COG1570	exodeoxyribonuclease VII activity
Csp1_RS04810	COG0628	permease
Csp1_RS04815	COG0012	GTP binding
Csp1_RS04820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Csp1_RS04835	COG0024	Methionine aminopeptidase
Csp1_RS04850	COG2354	Protein conserved in bacteria
Csp1_RS04885	COG1217	gtp-binding protein TYPA
Csp1_RS04895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Csp1_RS04915	COG2171	N-acyltransferase activity
Csp1_RS04920	COG1113	amino acid transport
Csp1_RS04925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Csp1_RS04930	COG1611	Belongs to the LOG family
Csp1_RS04940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Csp1_RS04955	COG0586	Pfam SNARE associated Golgi protein
Csp1_RS04965	COG1595	DNA-templated transcription, initiation
Csp1_RS04970	COG5662	AntiSigma factor
Csp1_RS04975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Csp1_RS04990	COG2239	Acts as a magnesium transporter
Csp1_RS04995	COG0598	Magnesium transport protein CorA
Csp1_RS05005	COG0508	dehydrogenase complex catalyzes the overall conversion of
Csp1_RS05005	COG0567	Dehydrogenase, E1 component
Csp1_RS05035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Csp1_RS05045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Csp1_RS05060	COG0018	arginyl-trna synthetase
Csp1_RS05065	COG0019	diaminopimelate decarboxylase activity
Csp1_RS05070	COG0460	homoserine dehydrogenase
Csp1_RS05075	COG0083	homoserine kinase activity
Csp1_RS05080	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS05085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Csp1_RS05095	COG2890	protein-(glutamine-N5) methyltransferase activity
Csp1_RS05115	COG0356	it plays a direct role in the translocation of protons across the membrane
Csp1_RS05120	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Csp1_RS05125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Csp1_RS05130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Csp1_RS05135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Csp1_RS05140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Csp1_RS05145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Csp1_RS05150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Csp1_RS05160	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Csp1_RS05175	COG1119	ATPase activity
Csp1_RS05195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Csp1_RS05200	COG0025	NhaP-type Na H and K H
Csp1_RS05210	COG0482	sulfurtransferase activity
Csp1_RS05225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Csp1_RS05235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Csp1_RS05250	COG0154	amidase activity
Csp1_RS05265	COG0205	6-phosphofructokinase activity
Csp1_RS05270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Csp1_RS05275	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Csp1_RS05280	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Csp1_RS05285	COG0435	Glutathione S-transferase
Csp1_RS05295	COG1279	arginine transmembrane transporter activity
Csp1_RS05300	COG0583	DNA-binding transcription factor activity
Csp1_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS05315	COG0129	dihydroxy-acid dehydratase activity
Csp1_RS05325	COG0668	transmembrane transport
Csp1_RS05330	COG0028	Belongs to the TPP enzyme family
Csp1_RS05335	COG0440	acetolactate synthase activity
Csp1_RS05340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Csp1_RS05360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Csp1_RS05365	COG1846	Transcriptional regulator
Csp1_RS05370	COG2814	Major facilitator Superfamily
Csp1_RS05375	COG2837	iron assimilation
Csp1_RS05390	COG0473	3-isopropylmalate dehydrogenase activity
Csp1_RS05400	COG0446	pyridine nucleotide-disulphide oxidoreductase
Csp1_RS05400	COG1902	pentaerythritol trinitrate reductase activity
Csp1_RS05410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Csp1_RS05410	COG0517	IMP dehydrogenase activity
Csp1_RS05420	COG0179	Fumarylacetoacetate (FAA) hydrolase
Csp1_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS05435	COG3622	Belongs to the hyi family
Csp1_RS05440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Csp1_RS05465	COG0588	phosphoglycerate mutase activity
Csp1_RS05490	COG1132	(ABC) transporter
Csp1_RS05505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Csp1_RS05515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Csp1_RS05520	COG0066	3-isopropylmalate dehydratase activity
Csp1_RS05525	COG0406	alpha-ribazole phosphatase activity
Csp1_RS05525	COG0494	nUDIX hydrolase
Csp1_RS05530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Csp1_RS05535	COG1181	Belongs to the D-alanine--D-alanine ligase family
Csp1_RS05545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Csp1_RS05550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Csp1_RS05555	COG1461	Dihydroxyacetone kinase
Csp1_RS05560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Csp1_RS05565	COG0511	ligase activity, forming carbon-carbon bonds
Csp1_RS05565	COG5016	pyruvate
Csp1_RS05570	COG0742	ribosomal rna small subunit methyltransferase
Csp1_RS05575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Csp1_RS05590	COG0571	ribonuclease III activity
Csp1_RS05595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Csp1_RS05600	COG1254	Belongs to the acylphosphatase family
Csp1_RS05635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Csp1_RS05640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Csp1_RS05645	COG0336	Belongs to the RNA methyltransferase TrmD family
Csp1_RS05660	COG0335	large ribosomal subunit rRNA binding
Csp1_RS05665	COG0681	Belongs to the peptidase S26 family
Csp1_RS05670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Csp1_RS05700	COG4974	Belongs to the 'phage' integrase family
Csp1_RS05710	COG0052	Belongs to the universal ribosomal protein uS2 family
Csp1_RS05715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Csp1_RS05725	COG0233	cytoplasmic translational termination
Csp1_RS05740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Csp1_RS05750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Csp1_RS05785	COG2814	Major facilitator Superfamily
Csp1_RS05795	COG1070	Carbohydrate kinase
Csp1_RS05820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Csp1_RS05825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Csp1_RS05850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Csp1_RS05875	COG1609	Transcriptional regulator
Csp1_RS05880	COG2233	PERMEase
Csp1_RS05885	COG0402	S-adenosylhomocysteine deaminase activity
Csp1_RS05895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Csp1_RS05900	COG2855	membrane
Csp1_RS05920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Csp1_RS05940	COG0579	oxidoreductase
Csp1_RS05950	COG3022	response to hydroperoxide
Csp1_RS05955	COG0442	prolyl-tRNA aminoacylation
Csp1_RS05965	COG0779	Required for maturation of 30S ribosomal subunits
Csp1_RS05980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Csp1_RS05985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Csp1_RS05995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Csp1_RS06010	COG2079	MmgE PrpD family protein
Csp1_RS06020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Csp1_RS06030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Csp1_RS06035	COG1185	polyribonucleotide nucleotidyltransferase activity
Csp1_RS06040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Csp1_RS06050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Csp1_RS06055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Csp1_RS06065	COG1674	ftsk spoiiie
Csp1_RS06080	COG1546	Belongs to the CinA family
Csp1_RS06080	COG1058	Belongs to the CinA family
Csp1_RS06085	COG1396	sequence-specific DNA binding
Csp1_RS06090	COG1842	Phage shock protein A
Csp1_RS06095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Csp1_RS06100	COG1122	ATPase activity
Csp1_RS06105	COG1268	BioY protein
Csp1_RS06115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Csp1_RS06125	COG0765	amino acid transport
Csp1_RS06130	COG0765	amino acid transport
Csp1_RS06135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Csp1_RS06140	COG1126	abc transporter atp-binding protein
Csp1_RS06145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Csp1_RS06155	COG1196	nuclear chromosome segregation
Csp1_RS06160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Csp1_RS06165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Csp1_RS06180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Csp1_RS06185	COG2233	PERMEase
Csp1_RS06190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Csp1_RS06200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Csp1_RS06205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Csp1_RS06215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Csp1_RS06220	COG1643	Atp-dependent helicase
Csp1_RS06235	COG0450	alkyl hydroperoxide reductase
Csp1_RS06240	COG0583	DNA-binding transcription factor activity
Csp1_RS06265	COG1321	iron dependent repressor
Csp1_RS06275	COG1490	D-aminoacyl-tRNA deacylase activity
Csp1_RS06330	COG0756	dUTP diphosphatase activity
Csp1_RS06345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Csp1_RS06350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Csp1_RS06355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Csp1_RS06370	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Csp1_RS06375	COG3253	May function as heme-dependent peroxidase
Csp1_RS06380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Csp1_RS06435	COG2837	iron assimilation
Csp1_RS06440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Csp1_RS06450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Csp1_RS06455	COG1560	Kdo2-lipid A biosynthetic process
Csp1_RS06460	COG0438	transferase activity, transferring glycosyl groups
Csp1_RS06470	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Csp1_RS06475	COG1946	Acyl-CoA thioesterase
Csp1_RS06480	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Csp1_RS06485	COG0217	transcriptional regulatory protein
Csp1_RS06500	COG0632	four-way junction helicase activity
Csp1_RS06505	COG2255	four-way junction helicase activity
Csp1_RS06520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Csp1_RS06530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Csp1_RS06535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Csp1_RS06545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Csp1_RS06550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Csp1_RS06555	COG0124	histidyl-tRNA synthetase
Csp1_RS06560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Csp1_RS06565	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS06580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Csp1_RS06585	COG1597	lipid kinase activity
Csp1_RS06610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Csp1_RS06625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Csp1_RS06630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Csp1_RS06640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Csp1_RS06650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Csp1_RS06655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Csp1_RS06660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Csp1_RS06670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Csp1_RS06675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Csp1_RS06680	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Csp1_RS06685	COG0540	Belongs to the ATCase OTCase family
Csp1_RS06690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Csp1_RS06700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Csp1_RS06715	COG0194	GDP metabolic process
Csp1_RS06720	COG1758	RNA polymerase activity
Csp1_RS06730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Csp1_RS06740	COG0242	peptide deformylase activity
Csp1_RS06745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Csp1_RS06755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Csp1_RS06760	COG0067	glutamate synthase
Csp1_RS06760	COG0070	glutamate synthase
Csp1_RS06760	COG0069	glutamate synthase activity
Csp1_RS06785	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Csp1_RS06795	COG0322	excinuclease ABC activity
Csp1_RS06800	COG1660	Displays ATPase and GTPase activities
Csp1_RS06810	COG1481	regulation of sporulation
Csp1_RS06815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Csp1_RS06820	COG0126	phosphoglycerate kinase activity
Csp1_RS06825	COG0149	triose-phosphate isomerase activity
Csp1_RS06835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Csp1_RS06840	COG0363	glucosamine-6-phosphate deaminase activity
Csp1_RS06855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Csp1_RS06865	COG0109	protoheme IX farnesyltransferase activity
Csp1_RS06920	COG0719	Fe-S assembly protein
Csp1_RS06925	COG0396	ATPase activity
Csp1_RS06935	COG0822	iron-sulfur transferase activity
Csp1_RS06950	COG0488	(ABC) transporter
Csp1_RS06960	COG2848	UPF0210 protein
Csp1_RS06970	COG1309	transcriptional regulator
Csp1_RS06975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Csp1_RS06980	COG0791	NLP P60 protein
Csp1_RS06980	COG3883	PFAM NLP P60 protein
Csp1_RS07015	COG0167	dihydroorotate dehydrogenase activity
Csp1_RS07025	COG1968	undecaprenyl-diphosphatase activity
Csp1_RS07030	COG0215	cysteine-tRNA ligase activity
Csp1_RS07040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Csp1_RS07050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Csp1_RS07055	COG1027	Aspartate ammonia-lyase
Csp1_RS07060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Csp1_RS07070	COG0277	FAD linked oxidase domain protein
Csp1_RS07075	COG0277	FAD linked oxidase domain protein
Csp1_RS07090	COG1222	aaa ATPase
Csp1_RS07095	COG4122	O-methyltransferase activity
Csp1_RS07105	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Csp1_RS07110	COG2378	regulation of single-species biofilm formation
Csp1_RS07120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Csp1_RS07125	COG0805	protein transport
Csp1_RS07140	COG0300	oxidoreductase activity
Csp1_RS07155	COG0463	Glycosyl transferase, family 2
Csp1_RS07185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Csp1_RS07220	COG2226	methyltransferase
Csp1_RS07225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Csp1_RS07235	COG0561	phosphatase activity
Csp1_RS07240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Csp1_RS07260	COG0351	phosphomethylpyrimidine kinase
Csp1_RS07270	COG1764	response to oxidative stress
Csp1_RS07275	COG1846	Transcriptional regulator
Csp1_RS07295	COG3573	Dehydrogenase
Csp1_RS07300	COG0477	Major facilitator Superfamily
Csp1_RS07315	COG1252	NADH dehydrogenase
Csp1_RS07320	COG0351	phosphomethylpyrimidine kinase
Csp1_RS07320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Csp1_RS07320	COG0352	thiamine-phosphate diphosphorylase activity
Csp1_RS07330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Csp1_RS07335	COG0513	Belongs to the DEAD box helicase family
Csp1_RS07340	COG1253	flavin adenine dinucleotide binding
Csp1_RS07370	COG1716	ATPase activity
Csp1_RS07375	COG0653	protein targeting
Csp1_RS07385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Csp1_RS07400	COG1305	Transglutaminase-like
Csp1_RS07430	COG2207	Transcriptional regulator
Csp1_RS07435	COG4607	ABC-type enterochelin transport system periplasmic component
Csp1_RS07445	COG1160	GTP binding
Csp1_RS07450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Csp1_RS07460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Csp1_RS07465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Csp1_RS07480	COG0494	nUDIX hydrolase
Csp1_RS07485	COG0504	CTP synthase activity
Csp1_RS07505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Csp1_RS07520	COG0647	UMP catabolic process
Csp1_RS07545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Csp1_RS07550	COG2835	tetraacyldisaccharide 4'-kinase activity
Csp1_RS07560	COG0137	argininosuccinate synthase activity
Csp1_RS07570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Csp1_RS07575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Csp1_RS07580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Csp1_RS07585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Csp1_RS07590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Csp1_RS07595	COG0072	phenylalanine-tRNA ligase activity
Csp1_RS07595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Csp1_RS07600	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Csp1_RS07610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Csp1_RS07655	COG0237	dephospho-CoA kinase activity
Csp1_RS07670	COG0183	Belongs to the thiolase family
Csp1_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS07680	COG2030	dehydratase
Csp1_RS07685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Csp1_RS07695	COG0583	DNA-binding transcription factor activity
Csp1_RS07700	COG0789	Transcriptional regulator
Csp1_RS07705	COG2814	Major facilitator Superfamily
Csp1_RS07710	COG0604	alcohol dehydrogenase
Csp1_RS07715	COG2249	NAD(P)H dehydrogenase (quinone) activity
Csp1_RS07765	COG0477	Major facilitator Superfamily
Csp1_RS07780	COG2814	Major facilitator Superfamily
Csp1_RS07785	COG0657	acetylesterase activity
Csp1_RS07795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS07820	COG0604	alcohol dehydrogenase
Csp1_RS07835	COG0473	3-isopropylmalate dehydrogenase activity
Csp1_RS07845	COG1309	transcriptional regulator
Csp1_RS07865	COG2365	Tyrosine phosphatase family
Csp1_RS07870	COG0189	ligase activity
Csp1_RS07875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Csp1_RS07885	COG1126	abc transporter atp-binding protein
Csp1_RS07915	COG0469	pyruvate kinase activity
Csp1_RS07920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Csp1_RS07925	COG0159	tryptophan synthase activity
Csp1_RS07935	COG0134	indole-3-glycerol-phosphate synthase activity
Csp1_RS07945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Csp1_RS07950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Csp1_RS07960	COG0483	inositol monophosphate 1-phosphatase activity
Csp1_RS07965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Csp1_RS07980	COG0131	Imidazoleglycerol-phosphate dehydratase
Csp1_RS07985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Csp1_RS08040	COG1739	Uncharacterized protein family UPF0029
Csp1_RS08065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Csp1_RS08095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Csp1_RS08110	COG0252	asparaginase activity
Csp1_RS08130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Csp1_RS08135	COG3599	regulation of cell shape
Csp1_RS08150	COG1496	oxidoreductase activity
Csp1_RS08155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Csp1_RS08160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Csp1_RS08165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Csp1_RS08170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Csp1_RS08180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Csp1_RS08185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Csp1_RS08195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Csp1_RS08200	COG0768	penicillin binding
Csp1_RS08210	COG0275	rRNA processing
Csp1_RS08215	COG2001	Belongs to the MraZ family
Csp1_RS08240	COG0142	geranyltranstransferase activity
Csp1_RS08255	COG0515	serine threonine protein kinase
Csp1_RS08255	COG2815	serine threonine protein kinase
Csp1_RS08260	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Csp1_RS08275	COG5650	phosphatidylinositol metabolic process
Csp1_RS08280	COG0204	Acyl-transferase
Csp1_RS08280	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS08285	COG1940	carbohydrate kinase activity
Csp1_RS08290	COG0438	transferase activity, transferring glycosyl groups
Csp1_RS08295	COG0791	NLP P60 protein
Csp1_RS08300	COG0791	NLP P60 protein
Csp1_RS08325	COG1845	cytochrome c oxidase, subunit III
Csp1_RS08330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Csp1_RS08340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Csp1_RS08365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Csp1_RS08375	COG0508	dehydrogenase complex catalyzes the overall conversion of
Csp1_RS08380	COG0321	lipoyl(octanoyl) transferase activity
Csp1_RS08385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Csp1_RS08400	COG0174	glutamine synthetase
Csp1_RS08405	COG1064	alcohol dehydrogenase
Csp1_RS08410	COG1960	acyl-CoA dehydrogenase activity
Csp1_RS08415	COG1960	acyl-CoA dehydrogenase activity
Csp1_RS08435	COG0352	thiamine-phosphate diphosphorylase activity
Csp1_RS08440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Csp1_RS08450	COG2022	thiamine diphosphate biosynthetic process
Csp1_RS08460	COG2223	nitrite transmembrane transporter activity
Csp1_RS08480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Csp1_RS08485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS08505	COG0174	glutamine synthetase
Csp1_RS08510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Csp1_RS08525	COG2149	membrane
Csp1_RS08545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Csp1_RS08545	COG3323	Protein of unknown function (DUF1653)
Csp1_RS08585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Csp1_RS08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Csp1_RS08615	COG1741	Belongs to the pirin family
Csp1_RS08620	COG1937	Protein conserved in bacteria
Csp1_RS08650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Csp1_RS08670	COG0423	glycine-tRNA ligase activity
Csp1_RS08685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Csp1_RS08690	COG1381	Involved in DNA repair and RecF pathway recombination
Csp1_RS08725	COG1420	regulation of RNA biosynthetic process
Csp1_RS08750	COG0339	signal peptide processing
Csp1_RS08765	COG1132	(ABC) transporter
Csp1_RS08770	COG3237	CsbD-like
Csp1_RS08805	COG1250	3-hydroxyacyl-CoA dehydrogenase
Csp1_RS08810	COG1309	transcriptional regulator
Csp1_RS08815	COG2423	ornithine cyclodeaminase activity
Csp1_RS08835	COG0745	RESPONSE REGULATOR receiver
Csp1_RS08840	COG3290	protein histidine kinase activity
Csp1_RS08845	COG2851	Citrate transporter
Csp1_RS08850	COG0004	ammonium transporteR
Csp1_RS08875	COG0004	ammonium transporteR
Csp1_RS08895	COG0544	peptidyl-prolyl cis-trans isomerase activity
Csp1_RS08905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Csp1_RS08915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Csp1_RS08930	COG2197	response regulator
Csp1_RS08965	COG3135	benzoate transporter
Csp1_RS08970	COG1063	alcohol dehydrogenase
Csp1_RS08980	COG0402	S-adenosylhomocysteine deaminase activity
Csp1_RS08985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Csp1_RS08995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Csp1_RS09000	COG1609	Transcriptional regulator
Csp1_RS09015	COG2966	Psort location CytoplasmicMembrane, score
Csp1_RS09025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Csp1_RS09055	COG4172	Belongs to the ABC transporter superfamily
Csp1_RS09090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Csp1_RS09095	COG1116	anion transmembrane transporter activity
Csp1_RS09110	COG2271	Major facilitator Superfamily
Csp1_RS09115	COG1301	dicarboxylic acid transport
Csp1_RS09140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Csp1_RS09155	COG0583	DNA-binding transcription factor activity
Csp1_RS09170	COG2851	Citrate transporter
Csp1_RS09175	COG0583	DNA-binding transcription factor activity
Csp1_RS09220	COG0481	GTPase activity
Csp1_RS09235	COG2818	Glycosylase
Csp1_RS09240	COG0268	Binds directly to 16S ribosomal RNA
Csp1_RS09245	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS09285	COG1307	EDD domain protein, DegV family
Csp1_RS09290	COG0406	alpha-ribazole phosphatase activity
Csp1_RS09300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Csp1_RS09315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Csp1_RS09320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Csp1_RS09325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Csp1_RS09330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Csp1_RS09335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Csp1_RS09340	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Csp1_RS09345	COG1530	ribonuclease E activity
Csp1_RS09350	COG0105	UTP biosynthetic process
Csp1_RS09365	COG0285	dihydrofolate synthase activity
Csp1_RS09370	COG0525	valine-tRNA ligase activity
Csp1_RS09375	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS09390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Csp1_RS09395	COG0508	dehydrogenase complex catalyzes the overall conversion of
Csp1_RS09395	COG0508	dehydrogenase complex catalyzes the overall conversion of
Csp1_RS09400	COG0022	dehydrogenase e1 component
Csp1_RS09405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Csp1_RS09410	COG3284	Transcriptional regulator
Csp1_RS09445	COG2233	PERMEase
Csp1_RS09450	COG0039	L-malate dehydrogenase activity
Csp1_RS09460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Csp1_RS09475	COG0740	serine-type endopeptidase activity
Csp1_RS09485	COG0544	peptidyl-prolyl cis-trans isomerase activity
Csp1_RS09520	COG3237	CsbD-like
Csp1_RS09530	COG0028	Belongs to the TPP enzyme family
Csp1_RS09555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Csp1_RS09565	COG2346	COG2346, Truncated hemoglobins
Csp1_RS09570	COG0730	response to heat
Csp1_RS09580	COG0824	Thioesterase
Csp1_RS09595	COG3336	cytochrome c oxidase
Csp1_RS09605	COG0300	oxidoreductase activity
Csp1_RS09610	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Csp1_RS09630	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Csp1_RS09630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Csp1_RS09635	COG0514	ATP-dependent DNA helicase (RecQ)
Csp1_RS09640	COG0095	Lipoate-protein ligase
Csp1_RS09660	COG1132	(ABC) transporter
Csp1_RS09665	COG1132	(ABC) transporter
Csp1_RS09695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS09730	COG0439	Biotin carboxylase
Csp1_RS09735	COG3665	Urea carboxylase-associated protein
Csp1_RS09745	COG2076	Multidrug Resistance protein
Csp1_RS09755	COG1376	ErfK ybiS ycfS ynhG family protein
Csp1_RS09785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Csp1_RS09790	COG2814	Major facilitator Superfamily
Csp1_RS09795	COG1024	Enoyl-CoA hydratase
Csp1_RS09800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS09810	COG4974	Belongs to the 'phage' integrase family
Csp1_RS09815	COG1950	PFAM Membrane protein of
Csp1_RS09920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Csp1_RS09930	COG1566	PFAM secretion protein HlyD family protein
Csp1_RS09940	COG1473	amidohydrolase
Csp1_RS09955	COG1234	tRNA 3'-trailer cleavage
Csp1_RS09980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Csp1_RS09985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Csp1_RS09995	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS10005	COG0560	Phosphoserine phosphatase
Csp1_RS10005	COG3830	Belongs to the UPF0237 family
Csp1_RS10010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Csp1_RS10025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Csp1_RS10045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Csp1_RS10075	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS10095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Csp1_RS10100	COG2177	Part of the ABC transporter FtsEX involved in
Csp1_RS10105	COG2884	Cell division ATP-binding protein ftsE
Csp1_RS10115	COG0483	inositol monophosphate 1-phosphatase activity
Csp1_RS10120	COG0366	Alpha amylase catalytic
Csp1_RS10140	COG0483	inositol monophosphate 1-phosphatase activity
Csp1_RS10145	COG0166	Belongs to the GPI family
Csp1_RS10150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Csp1_RS10155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Csp1_RS10165	COG0415	Belongs to the DNA photolyase family
Csp1_RS10170	COG1201	RNA secondary structure unwinding
Csp1_RS10180	COG1215	transferase activity, transferring glycosyl groups
Csp1_RS10225	COG3764	Sortase (surface protein transpeptidase)
Csp1_RS10235	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Csp1_RS10245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Csp1_RS10255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Csp1_RS10270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS10275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Csp1_RS10285	COG0656	L-ascorbic acid biosynthetic process
Csp1_RS10300	COG4152	abc transporter atp-binding protein
Csp1_RS10305	COG1668	transmembrane transport
Csp1_RS10315	COG0545	Peptidyl-prolyl cis-trans isomerase
Csp1_RS10320	COG0372	Belongs to the citrate synthase family
Csp1_RS10340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Csp1_RS10345	COG2252	PERMEase
Csp1_RS10360	COG2814	Major facilitator Superfamily
Csp1_RS10370	COG1278	Cold shock
Csp1_RS10375	COG1652	LysM domain
Csp1_RS10390	COG1061	Type III restriction enzyme res subunit
Csp1_RS10400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Csp1_RS10410	COG4770	biotin carboxylase activity
Csp1_RS10420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Csp1_RS10425	COG1228	amidohydrolase
Csp1_RS10430	COG0402	S-adenosylhomocysteine deaminase activity
Csp1_RS10450	COG1174	glycine betaine transport
Csp1_RS10460	COG0517	IMP dehydrogenase activity
Csp1_RS10460	COG1125	glycine betaine transport
Csp1_RS10475	COG4336	lyase activity
Csp1_RS10480	COG1914	H( )-stimulated, divalent metal cation uptake system
Csp1_RS10525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Csp1_RS10530	COG2197	response regulator
Csp1_RS10540	COG1024	Enoyl-CoA hydratase
Csp1_RS10545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Csp1_RS10550	COG1045	serine acetyltransferase
Csp1_RS10590	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Csp1_RS10620	COG3265	gluconokinase activity
Csp1_RS10625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Csp1_RS10645	COG0456	acetyltransferase
Csp1_RS10650	COG0745	RESPONSE REGULATOR receiver
Csp1_RS10660	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Csp1_RS10680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Csp1_RS10690	COG1607	acyl-coa hydrolase
Csp1_RS10695	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Csp1_RS10700	COG0463	Glycosyl transferase, family 2
Csp1_RS10705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Csp1_RS10710	COG0047	phosphoribosylformylglycinamidine synthase activity
Csp1_RS10715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Csp1_RS10720	COG1301	dicarboxylic acid transport
Csp1_RS10730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Csp1_RS10740	COG0601	transmembrane transport
Csp1_RS10745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Csp1_RS10755	COG2079	MmgE PrpD family protein
Csp1_RS10760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Csp1_RS10765	COG0372	Belongs to the citrate synthase family
Csp1_RS10770	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Csp1_RS10780	COG1280	lysine exporter protein (LysE YggA)
Csp1_RS10785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Csp1_RS10805	COG0151	Belongs to the GarS family
Csp1_RS10810	COG0537	adenosine 5'-monophosphoramidase activity
Csp1_RS10825	COG5002	protein histidine kinase activity
Csp1_RS10830	COG0745	RESPONSE REGULATOR receiver
Csp1_RS10855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Csp1_RS10860	COG1396	sequence-specific DNA binding
Csp1_RS10875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Csp1_RS10880	COG3048	D-serine ammonia-lyase activity
Csp1_RS10915	COG0601	transmembrane transport
Csp1_RS10920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Csp1_RS10970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Csp1_RS10985	COG1609	Transcriptional regulator
Csp1_RS10990	COG0803	Belongs to the bacterial solute-binding protein 9 family
Csp1_RS10995	COG3842	ATPase activity
Csp1_RS11000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Csp1_RS11005	COG1902	pentaerythritol trinitrate reductase activity
Csp1_RS11015	COG0477	Major facilitator Superfamily
Csp1_RS11020	COG0215	cysteine-tRNA ligase activity
Csp1_RS11025	COG0179	Fumarylacetoacetate (FAA) hydrolase
Csp1_RS11045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Csp1_RS11055	COG0288	reversible hydration of carbon dioxide
Csp1_RS11060	COG1194	a g-specific adenine glycosylase
Csp1_RS11070	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS11080	COG2072	flavoprotein involved in K transport
Csp1_RS11085	COG1960	acyl-CoA dehydrogenase activity
Csp1_RS11095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Csp1_RS11130	COG1959	2 iron, 2 sulfur cluster binding
Csp1_RS11135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Csp1_RS11140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Csp1_RS11175	COG0302	gtp cyclohydrolase
Csp1_RS11180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Csp1_RS11195	COG2027	D-alanyl-D-alanine carboxypeptidase
Csp1_RS11210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Csp1_RS11220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Csp1_RS11230	COG2326	polyphosphate kinase activity
Csp1_RS11235	COG0459	protein refolding
Csp1_RS11250	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Csp1_RS11265	COG0477	Major facilitator Superfamily
Csp1_RS11285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Csp1_RS11295	COG2814	Major facilitator Superfamily
Csp1_RS11305	COG1131	(ABC) transporter
Csp1_RS11315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Csp1_RS11325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Csp1_RS11330	COG0280	phosphate acetyltransferase
Csp1_RS11335	COG0730	response to heat
Csp1_RS11360	COG1132	(ABC) transporter
Csp1_RS11365	COG1132	(ABC) transporter
Csp1_RS11375	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Csp1_RS11425	COG1054	Belongs to the UPF0176 family
Csp1_RS11435	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Csp1_RS11460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Csp1_RS11475	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS11495	COG1960	acyl-CoA dehydrogenase activity
Csp1_RS11545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Csp1_RS11555	COG1116	anion transmembrane transporter activity
Csp1_RS11560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Csp1_RS11590	COG4129	membrane
Csp1_RS11605	COG0191	fructose-bisphosphate aldolase activity
Csp1_RS11625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Csp1_RS11635	COG0509	glycine decarboxylation via glycine cleavage system
Csp1_RS11640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Csp1_RS11645	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Csp1_RS11645	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Csp1_RS11680	COG2860	membrane
Csp1_RS11705	COG0542	response to heat
Csp1_RS11720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Csp1_RS11725	COG4172	Belongs to the ABC transporter superfamily
Csp1_RS11740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS11780	COG0659	secondary active sulfate transmembrane transporter activity
Csp1_RS11805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Csp1_RS11820	COG0531	amino acid
Csp1_RS11830	COG0789	Transcriptional regulator
Csp1_RS11835	COG0484	heat shock protein binding
Csp1_RS11850	COG0443	Heat shock 70 kDa protein
Csp1_RS11875	COG2197	response regulator
Csp1_RS11885	COG0717	Belongs to the dCTP deaminase family
Csp1_RS11910	COG0489	protein tyrosine kinase activity
Csp1_RS11940	COG0247	lactate metabolic process
Csp1_RS11945	COG1139	Iron-sulfur cluster binding protein
Csp1_RS11950	COG1556	Lactate utilization protein
Csp1_RS11965	COG0477	Major facilitator Superfamily
Csp1_RS11970	COG1902	pentaerythritol trinitrate reductase activity
Csp1_RS11980	COG1472	Belongs to the glycosyl hydrolase 3 family
Csp1_RS12030	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Csp1_RS12030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Csp1_RS12045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Csp1_RS12060	COG4176	ABC-type proline glycine betaine transport system permease component
Csp1_RS12065	COG3448	diguanylate cyclase activity
Csp1_RS12065	COG4175	Glycine betaine
Csp1_RS12070	COG0438	transferase activity, transferring glycosyl groups
Csp1_RS12085	COG2814	Major facilitator Superfamily
Csp1_RS12095	COG0500	methyltransferase
Csp1_RS12100	COG0183	Belongs to the thiolase family
Csp1_RS12105	COG1250	3-hydroxyacyl-CoA dehydrogenase
Csp1_RS12105	COG1024	Enoyl-CoA hydratase
Csp1_RS12110	COG0586	Pfam SNARE associated Golgi protein
Csp1_RS12115	COG2197	response regulator
Csp1_RS12120	COG4585	Histidine kinase
Csp1_RS12125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Csp1_RS12130	COG0805	protein transport
Csp1_RS12135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Csp1_RS12165	COG1309	transcriptional regulator
Csp1_RS12195	COG2391	methyltransferase activity
Csp1_RS12210	COG3527	Alpha-acetolactate decarboxylase
Csp1_RS12220	COG0803	Belongs to the bacterial solute-binding protein 9 family
Csp1_RS12230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Csp1_RS12235	COG1121	(ABC) transporter
Csp1_RS12240	COG0523	cobalamin synthesis protein
Csp1_RS12250	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Csp1_RS12265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Csp1_RS12285	COG0583	DNA-binding transcription factor activity
Csp1_RS12290	COG2814	Major facilitator Superfamily
Csp1_RS12310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Csp1_RS12315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Csp1_RS12315	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Csp1_RS12315	COG3321	synthase
Csp1_RS12320	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS12325	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
Csp1_RS12335	COG5479	isomerase activity
Csp1_RS12335	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Csp1_RS12340	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Csp1_RS12345	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Csp1_RS12350	COG0671	phosphoesterase, PA-phosphatase related
Csp1_RS12355	COG1216	Glycosyl transferase, family 2
Csp1_RS12365	COG1120	ATPase activity
Csp1_RS12370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS12375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS12380	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Csp1_RS12395	COG2375	cellular response to nickel ion
Csp1_RS12410	COG1132	(ABC) transporter
Csp1_RS12415	COG1132	(ABC) transporter
Csp1_RS12420	COG0318	PFAM AMP-dependent synthetase and ligase
Csp1_RS12430	COG0604	alcohol dehydrogenase
Csp1_RS12445	COG1780	Probably involved in ribonucleotide reductase function
Csp1_RS12455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Csp1_RS12460	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Csp1_RS12470	COG0561	phosphatase activity
Csp1_RS12480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Csp1_RS12495	COG0477	Major facilitator Superfamily
Csp1_RS12505	COG0077	Prephenate dehydratase
Csp1_RS12510	COG0154	amidase activity
Csp1_RS12525	COG1316	TRANSCRIPTIONal
Csp1_RS12535	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Csp1_RS12555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Csp1_RS12560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Csp1_RS12565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Csp1_RS12585	COG2197	response regulator
Csp1_RS12620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Csp1_RS12675	COG0564	pseudouridine synthase activity
Csp1_RS12710	COG3590	peptidase
Csp1_RS12725	COG2501	S4 domain
Csp1_RS12730	COG1280	lysine exporter protein (LysE YggA)
Csp1_RS12755	COG0604	alcohol dehydrogenase
Csp1_RS12805	COG1216	Glycosyl transferase, family 2
Csp1_RS12845	COG0277	FAD linked oxidase domain protein
Csp1_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS12880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Csp1_RS12885	COG0183	Belongs to the thiolase family
Csp1_RS12890	COG1472	Belongs to the glycosyl hydrolase 3 family
Csp1_RS12900	COG3265	gluconokinase activity
Csp1_RS12905	COG3265	gluconokinase activity
Csp1_RS12915	COG1113	amino acid transport
Csp1_RS12955	COG1012	belongs to the aldehyde dehydrogenase family
Csp1_RS12975	COG2409	Drug exporters of the RND superfamily
Csp1_RS12980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Csp1_RS13015	COG2132	Multicopper oxidase
Csp1_RS13030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Csp1_RS13040	COG1984	allophanate hydrolase subunit 2
Csp1_RS13045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Csp1_RS13050	COG0439	Biotin carboxylase
Csp1_RS13060	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Csp1_RS13070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Csp1_RS13075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS13080	COG1120	ATPase activity
Csp1_RS13110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Csp1_RS13115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Csp1_RS13120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Csp1_RS13130	COG0154	amidase activity
Csp1_RS13135	COG1028	Short-chain dehydrogenase reductase Sdr
Csp1_RS13175	COG1468	defense response to virus
Csp1_RS13175	COG1518	maintenance of DNA repeat elements
Csp1_RS13210	COG1414	Transcriptional regulator
Csp1_RS13215	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Csp1_RS13225	COG0758	DNA mediated transformation
Csp1_RS13235	COG1715	Restriction endonuclease
Csp1_RS13250	COG0076	glutamate decarboxylase activity
Csp1_RS13255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Csp1_RS13260	COG1535	isochorismatase
Csp1_RS13260	COG3433	isochorismatase activity
Csp1_RS13265	COG4592	Periplasmic binding protein
Csp1_RS13270	COG1120	ATPase activity
Csp1_RS13275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS13280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Csp1_RS13285	COG1021	2,3-dihydroxybenzoate-AMP ligase
Csp1_RS13295	COG1169	isochorismate synthase
Csp1_RS13300	COG2814	Major facilitator Superfamily
Csp1_RS13305	COG1842	Phage shock protein A
Csp1_RS13320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Csp1_RS13325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Csp1_RS13330	COG2353	YceI-like domain
Csp1_RS13340	COG0305	Participates in initiation and elongation during chromosome replication
Csp1_RS13345	COG0359	binds to the 23S rRNA
Csp1_RS13350	COG0629	single-stranded DNA binding
Csp1_RS13355	COG0360	Binds together with S18 to 16S ribosomal RNA
Csp1_RS13365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Csp1_RS13375	COG1260	myo-inositol-1-phosphate synthase
Csp1_RS13395	COG0495	leucyl-tRNA aminoacylation
Csp1_RS13415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Csp1_RS13420	COG1216	Glycosyl transferase, family 2
Csp1_RS13460	COG1215	transferase activity, transferring glycosyl groups
Csp1_RS13475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Csp1_RS13495	COG4607	ABC-type enterochelin transport system periplasmic component
Csp1_RS13505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Csp1_RS13510	COG0617	tRNA 3'-terminal CCA addition
Csp1_RS13535	COG1595	DNA-templated transcription, initiation
Csp1_RS13545	COG3118	belongs to the thioredoxin family
Csp1_RS13550	COG3409	Peptidoglycan-binding domain 1 protein
Csp1_RS13550	COG0860	N-Acetylmuramoyl-L-alanine amidase
Csp1_RS13565	COG1192	Involved in chromosome partitioning
Csp1_RS13570	COG0357	Ribosomal RNA small subunit methyltransferase G
Csp1_RS13575	COG0706	membrane insertase activity
Csp1_RS13580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Csp1_RS13585	COG0594	ribonuclease P activity
Csp1_RS13590	COG0230	Belongs to the bacterial ribosomal protein bL34 family