locus-tag	class	description
CP106_RS00010	COG0592	DNA-directed DNA polymerase activity
CP106_RS00025	COG0187	DNA topoisomerase II activity
CP106_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP106_RS00140	COG1120	ATPase activity
CP106_RS00145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS00150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS00155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP106_RS00165	COG0515	serine threonine protein kinase
CP106_RS00165	COG2815	serine threonine protein kinase
CP106_RS00170	COG0515	serine threonine protein kinase
CP106_RS00175	COG0768	penicillin binding
CP106_RS00180	COG0772	Belongs to the SEDS family
CP106_RS00195	COG1716	ATPase activity
CP106_RS00195	COG1716	ATPase activity
CP106_RS00230	COG0366	Alpha amylase catalytic
CP106_RS00285	COG1125	glycine betaine transport
CP106_RS00285	COG0517	IMP dehydrogenase activity
CP106_RS00290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP106_RS00310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP106_RS00320	COG3757	hydrolase, family 25
CP106_RS00320	COG3409	Peptidoglycan-binding domain 1 protein
CP106_RS00345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CP106_RS00375	COG1846	Transcriptional regulator
CP106_RS00390	COG3180	Ammonia monooxygenase
CP106_RS00400	COG0730	response to heat
CP106_RS00415	COG1643	Atp-dependent helicase
CP106_RS00425	COG0519	Catalyzes the synthesis of GMP from XMP
CP106_RS00435	COG0393	Putative heavy-metal-binding
CP106_RS00440	COG2501	S4 domain
CP106_RS00465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP106_RS00470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP106_RS00480	COG3590	peptidase
CP106_RS00510	COG1028	Short-chain dehydrogenase reductase Sdr
CP106_RS00515	COG0277	FAD linked oxidase domain protein
CP106_RS00545	COG1216	Glycosyl transferase, family 2
CP106_RS00555	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP106_RS00560	COG1121	(ABC) transporter
CP106_RS00565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP106_RS00570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP106_RS00600	COG0604	alcohol dehydrogenase
CP106_RS00635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP106_RS00635	COG1263	PTS System
CP106_RS00640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP106_RS00640	COG1263	PTS System
CP106_RS00640	COG2190	(PTS) system
CP106_RS00665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP106_RS00670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP106_RS00685	COG0287	Prephenate dehydrogenase
CP106_RS00705	COG2409	Drug exporters of the RND superfamily
CP106_RS00710	COG0343	queuine tRNA-ribosyltransferase activity
CP106_RS00720	COG2610	gluconate transmembrane transporter activity
CP106_RS00725	COG3265	gluconokinase activity
CP106_RS00730	COG1063	alcohol dehydrogenase
CP106_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
CP106_RS00745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP106_RS00770	COG2610	gluconate transmembrane transporter activity
CP106_RS00775	COG2084	Dehydrogenase
CP106_RS00785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP106_RS00790	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP106_RS00795	COG3442	glutamine amidotransferase
CP106_RS00800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP106_RS00815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP106_RS00820	COG2390	Transcriptional regulator
CP106_RS00825	COG0813	purine-nucleoside phosphorylase activity
CP106_RS00840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP106_RS00870	COG0527	aspartate kinase activity
CP106_RS00925	COG1840	ABC-type Fe3 transport system, periplasmic component
CP106_RS00930	COG2271	Major facilitator Superfamily
CP106_RS00960	COG0651	ATP synthesis coupled electron transport
CP106_RS01000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP106_RS01020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP106_RS01040	COG0494	nUDIX hydrolase
CP106_RS01120	COG1754	DNA topoisomerase type I activity
CP106_RS01120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP106_RS01125	COG1297	OPT oligopeptide transporter protein
CP106_RS01135	COG0470	DNA polymerase III
CP106_RS01150	COG0318	PFAM AMP-dependent synthetase and ligase
CP106_RS01160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CP106_RS01170	COG1088	dTDP-glucose 4,6-dehydratase activity
CP106_RS01180	COG1505	serine-type exopeptidase activity
CP106_RS01190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP106_RS01195	COG1396	sequence-specific DNA binding
CP106_RS01195	COG3800	Transcriptional regulator
CP106_RS01205	COG1053	succinate dehydrogenase
CP106_RS01210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP106_RS01220	COG2733	membrane
CP106_RS01245	COG1882	Formate acetyltransferase
CP106_RS01265	COG0318	PFAM AMP-dependent synthetase and ligase
CP106_RS01280	COG5002	protein histidine kinase activity
CP106_RS01285	COG0745	RESPONSE REGULATOR receiver
CP106_RS01305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP106_RS01315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP106_RS01315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP106_RS01345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP106_RS01345	COG1648	precorrin-2 dehydrogenase activity
CP106_RS01360	COG2217	Heavy metal translocating P-type atpase
CP106_RS01370	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP106_RS01385	COG0406	alpha-ribazole phosphatase activity
CP106_RS01405	COG0275	rRNA processing
CP106_RS01420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS01455	COG3069	C4-dicarboxylate transmembrane transporter activity
CP106_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
CP106_RS01475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP106_RS01475	COG0438	transferase activity, transferring glycosyl groups
CP106_RS01485	COG0039	L-malate dehydrogenase activity
CP106_RS01490	COG0644	oxidoreductase
CP106_RS01495	COG0142	geranyltranstransferase activity
CP106_RS01520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP106_RS01545	COG3579	cysteine-type endopeptidase activity
CP106_RS01550	COG1902	pentaerythritol trinitrate reductase activity
CP106_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP106_RS01580	COG1121	(ABC) transporter
CP106_RS01585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP106_RS01625	COG1131	(ABC) transporter
CP106_RS01640	COG0701	Predicted permease
CP106_RS01710	COG1302	Protein conserved in bacteria
CP106_RS01805	COG0814	amino acid
CP106_RS01810	COG1760	l-serine dehydratase
CP106_RS01815	COG0252	asparaginase activity
CP106_RS01865	COG3833	ABC-type maltose transport systems, permease component
CP106_RS01885	COG3842	ATPase activity
CP106_RS01890	COG0201	protein transport
CP106_RS01940	COG0203	ribosomal protein L17
CP106_RS01960	COG1404	Belongs to the peptidase S8 family
CP106_RS01970	COG1674	ftsk spoiiie
CP106_RS02030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP106_RS02100	COG0516	GMP reductase activity
CP106_RS02145	COG2011	ABC-type metal ion transport system permease component
CP106_RS02155	COG1464	Belongs to the NlpA lipoprotein family
CP106_RS02160	COG1464	Belongs to the NlpA lipoprotein family
CP106_RS02175	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP106_RS02180	COG1121	(ABC) transporter
CP106_RS02190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP106_RS02190	COG1321	iron dependent repressor
CP106_RS02195	COG1321	iron dependent repressor
CP106_RS02200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CP106_RS02205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP106_RS02240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS02245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP106_RS02260	COG2838	Isocitrate dehydrogenase
CP106_RS02265	COG2814	Major facilitator Superfamily
CP106_RS02285	COG0180	Tryptophanyl-tRNA synthetase
CP106_RS02290	COG1295	ribonuclease BN
CP106_RS02295	COG1686	Belongs to the peptidase S11 family
CP106_RS02330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP106_RS02335	COG1473	amidohydrolase
CP106_RS02335	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP106_RS02360	COG4770	biotin carboxylase activity
CP106_RS02365	COG2897	thiosulfate sulfurtransferase activity
CP106_RS02370	COG0189	ligase activity
CP106_RS02375	COG2755	lipolytic protein G-D-S-L family
CP106_RS02375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP106_RS02385	COG0424	maF-like protein
CP106_RS02390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP106_RS02395	COG1609	Transcriptional regulator
CP106_RS02405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP106_RS02415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CP106_RS02415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CP106_RS02465	COG1316	TRANSCRIPTIONal
CP106_RS02530	COG0745	RESPONSE REGULATOR receiver
CP106_RS02535	COG5002	protein histidine kinase activity
CP106_RS02550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP106_RS02590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP106_RS02595	COG2135	peptidase activity
CP106_RS02600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP106_RS02635	COG0513	Belongs to the DEAD box helicase family
CP106_RS02670	COG2816	NAD+ diphosphatase activity
CP106_RS02695	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP106_RS02795	COG0483	inositol monophosphate 1-phosphatase activity
CP106_RS02800	COG0483	inositol monophosphate 1-phosphatase activity
CP106_RS02815	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CP106_RS02820	COG2884	Cell division ATP-binding protein ftsE
CP106_RS02825	COG2177	Part of the ABC transporter FtsEX involved in
CP106_RS02835	COG0288	reversible hydration of carbon dioxide
CP106_RS02885	COG1061	Type III restriction enzyme res subunit
CP106_RS02900	COG1652	LysM domain
CP106_RS02925	COG2252	PERMEase
CP106_RS02950	COG0372	Belongs to the citrate synthase family
CP106_RS02955	COG0545	Peptidyl-prolyl cis-trans isomerase
CP106_RS02970	COG0656	L-ascorbic acid biosynthetic process
CP106_RS02975	COG1024	Enoyl-CoA hydratase
CP106_RS02985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP106_RS02995	COG3757	hydrolase, family 25
CP106_RS03010	COG0534	Mate efflux family protein
CP106_RS03015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP106_RS03020	COG0019	diaminopimelate decarboxylase activity
CP106_RS03035	COG4166	transmembrane transport
CP106_RS03040	COG0601	transmembrane transport
CP106_RS03050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP106_RS03070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CP106_RS03085	COG1218	3'(2'),5'-bisphosphate nucleotidase
CP106_RS03090	COG1201	RNA secondary structure unwinding
CP106_RS03100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP106_RS03150	COG1126	abc transporter atp-binding protein
CP106_RS03155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP106_RS03160	COG0765	amino acid transport
CP106_RS03165	COG0765	amino acid transport
CP106_RS03175	COG1309	transcriptional regulator
CP106_RS03205	COG0254	rRNA binding
CP106_RS03215	COG0745	RESPONSE REGULATOR receiver
CP106_RS03220	COG2205	protein histidine kinase activity
CP106_RS03225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP106_RS03230	COG0315	cyclic pyranopterin monophosphate synthase activity
CP106_RS03230	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP106_RS03250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP106_RS03270	COG2259	Doxx family
CP106_RS03280	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CP106_RS03285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP106_RS03290	COG3949	Membrane
CP106_RS03305	COG0084	hydrolase, TatD family'
CP106_RS03310	COG3583	domain protein
CP106_RS03325	COG0488	(ABC) transporter
CP106_RS03340	COG2326	polyphosphate kinase activity
CP106_RS03375	COG0596	Alpha beta hydrolase
CP106_RS03380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CP106_RS03390	COG0193	aminoacyl-tRNA hydrolase activity
CP106_RS03395	COG2070	2-Nitropropane dioxygenase
CP106_RS03415	COG1523	belongs to the glycosyl hydrolase 13 family
CP106_RS03420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP106_RS03425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP106_RS03445	COG1309	transcriptional regulator
CP106_RS03455	COG0531	amino acid
CP106_RS03460	COG3956	TIGRFAM MazG family protein
CP106_RS03520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP106_RS03590	COG0114	fumarate hydratase activity
CP106_RS03595	COG1494	fructose-1,6-bisphosphatase
CP106_RS03630	COG0012	GTP binding
CP106_RS03645	COG2824	Alkylphosphonate utilization operon protein PhnA
CP106_RS03650	COG1132	(ABC) transporter
CP106_RS03655	COG1132	(ABC) transporter
CP106_RS03665	COG2354	Protein conserved in bacteria
CP106_RS03675	COG4721	ABC-type cobalt transport system, permease component
CP106_RS03680	COG1122	ATPase activity
CP106_RS03690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP106_RS03700	COG4166	transmembrane transport
CP106_RS03705	COG0601	transmembrane transport
CP106_RS03710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP106_RS03740	COG1217	gtp-binding protein TYPA
CP106_RS03745	COG4166	transmembrane transport
CP106_RS03780	COG1113	amino acid transport
CP106_RS03790	COG1113	amino acid transport
CP106_RS03800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP106_RS03805	COG1611	Belongs to the LOG family
CP106_RS03810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP106_RS03815	COG0463	Glycosyl transferase, family 2
CP106_RS03835	COG3527	Alpha-acetolactate decarboxylase
CP106_RS03840	COG0297	glycogen (starch) synthase activity
CP106_RS03850	COG4122	O-methyltransferase activity
CP106_RS03880	COG2239	Acts as a magnesium transporter
CP106_RS03890	COG0567	Dehydrogenase, E1 component
CP106_RS03890	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP106_RS03895	COG1132	(ABC) transporter
CP106_RS03905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP106_RS03910	COG2272	Belongs to the type-B carboxylesterase lipase family
CP106_RS03925	COG2017	converts alpha-aldose to the beta-anomer
CP106_RS03945	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP106_RS03975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP106_RS03980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP106_RS04005	COG1846	Transcriptional regulator
CP106_RS04020	COG1349	DNA-binding transcription factor activity
CP106_RS04035	COG1556	Lactate utilization protein
CP106_RS04040	COG1139	Iron-sulfur cluster binding protein
CP106_RS04045	COG0247	lactate metabolic process
CP106_RS04050	COG1620	l-lactate permease
CP106_RS04060	COG0019	diaminopimelate decarboxylase activity
CP106_RS04065	COG0460	homoserine dehydrogenase
CP106_RS04115	COG0356	it plays a direct role in the translocation of protons across the membrane
CP106_RS04120	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP106_RS04125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP106_RS04165	COG0346	lactoylglutathione lyase activity
CP106_RS04190	COG1119	ATPase activity
CP106_RS04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS04280	COG1120	ATPase activity
CP106_RS04290	COG0205	6-phosphofructokinase activity
CP106_RS04300	COG0667	Aldo Keto reductase
CP106_RS04310	COG0583	DNA-binding transcription factor activity
CP106_RS04335	COG0668	transmembrane transport
CP106_RS04375	COG0473	3-isopropylmalate dehydrogenase activity
CP106_RS04395	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP106_RS04425	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CP106_RS04460	COG0494	nUDIX hydrolase
CP106_RS04460	COG0406	alpha-ribazole phosphatase activity
CP106_RS04480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CP106_RS04485	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP106_RS04490	COG1461	Dihydroxyacetone kinase
CP106_RS04500	COG0511	ligase activity, forming carbon-carbon bonds
CP106_RS04505	COG0742	ribosomal rna small subunit methyltransferase
CP106_RS04530	COG0765	amino acid transport
CP106_RS04555	COG2226	methyltransferase
CP106_RS04560	COG0539	negative regulation of cytoplasmic translation
CP106_RS04570	COG0237	dephospho-CoA kinase activity
CP106_RS04590	COG3973	AAA domain
CP106_RS04615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP106_RS04630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP106_RS04645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP106_RS04660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP106_RS04665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP106_RS04685	COG0165	Argininosuccinate lyase
CP106_RS04690	COG2835	tetraacyldisaccharide 4'-kinase activity
CP106_RS04720	COG0647	UMP catabolic process
CP106_RS04750	COG0494	nUDIX hydrolase
CP106_RS04755	COG4974	Belongs to the 'phage' integrase family
CP106_RS04775	COG3104	oligopeptide transport
CP106_RS04780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP106_RS04790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP106_RS04805	COG1160	GTP binding
CP106_RS04810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CP106_RS04815	COG4106	trans-aconitate 2-methyltransferase activity
CP106_RS04820	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP106_RS04825	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP106_RS04830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP106_RS04835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS04840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS04845	COG1120	ATPase activity
CP106_RS04850	COG4264	IucA IucC family
CP106_RS04870	COG0653	protein targeting
CP106_RS04910	COG1253	flavin adenine dinucleotide binding
CP106_RS04915	COG0513	Belongs to the DEAD box helicase family
CP106_RS04920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP106_RS04930	COG0598	Magnesium transport protein CorA
CP106_RS04950	COG0477	Major facilitator Superfamily
CP106_RS04970	COG0463	Glycosyl transferase, family 2
CP106_RS05020	COG0300	oxidoreductase activity
CP106_RS05035	COG0805	protein transport
CP106_RS05045	COG2378	regulation of single-species biofilm formation
CP106_RS05065	COG4122	O-methyltransferase activity
CP106_RS05080	COG1362	aminopeptidase activity
CP106_RS05100	COG1027	Aspartate ammonia-lyase
CP106_RS05105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CP106_RS05145	COG0667	Aldo Keto reductase
CP106_RS05155	COG0167	dihydroorotate dehydrogenase activity
CP106_RS05180	COG1461	Dihydroxyacetone kinase
CP106_RS05185	COG2376	Dihydroxyacetone kinase
CP106_RS05195	COG0488	(ABC) transporter
CP106_RS05260	COG3883	PFAM NLP P60 protein
CP106_RS05260	COG0791	NLP P60 protein
CP106_RS05290	COG2848	UPF0210 protein
CP106_RS05305	COG1388	LysM domain
CP106_RS05305	COG4932	domain protein
CP106_RS05310	COG0488	(ABC) transporter
CP106_RS05315	COG2151	metal-sulfur cluster biosynthetic enzyme
CP106_RS05320	COG0822	iron-sulfur transferase activity
CP106_RS05330	COG0396	ATPase activity
CP106_RS05375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP106_RS05380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP106_RS05400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP106_RS05420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP106_RS05430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP106_RS05440	COG0322	excinuclease ABC activity
CP106_RS05470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP106_RS05485	COG0242	peptide deformylase activity
CP106_RS05525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP106_RS05535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP106_RS05550	COG1090	epimerase
CP106_RS05575	COG0006	proline dipeptidase activity
CP106_RS05580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP106_RS05585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP106_RS05590	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP106_RS05595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP106_RS05605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP106_RS05615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP106_RS05670	COG1760	l-serine dehydratase
CP106_RS05700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP106_RS05705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CP106_RS05720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP106_RS05735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP106_RS05740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP106_RS05770	COG1946	Acyl-CoA thioesterase
CP106_RS05785	COG0156	8-amino-7-oxononanoate synthase activity
CP106_RS05800	COG1560	Kdo2-lipid A biosynthetic process
CP106_RS05805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP106_RS05820	COG2837	iron assimilation
CP106_RS05870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP106_RS05875	COG3253	May function as heme-dependent peroxidase
CP106_RS05960	COG2890	protein-(glutamine-N5) methyltransferase activity
CP106_RS06000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP106_RS06005	COG0450	alkyl hydroperoxide reductase
CP106_RS06020	COG1643	Atp-dependent helicase
CP106_RS06040	COG1349	DNA-binding transcription factor activity
CP106_RS06045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP106_RS06050	COG1349	DNA-binding transcription factor activity
CP106_RS06055	COG1105	Belongs to the carbohydrate kinase PfkB family
CP106_RS06060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CP106_RS06060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP106_RS06060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP106_RS06065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP106_RS06070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP106_RS06080	COG2233	PERMEase
CP106_RS06085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP106_RS06100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP106_RS06115	COG1196	nuclear chromosome segregation
CP106_RS06135	COG2137	regulation of response to DNA damage stimulus
CP106_RS06140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP106_RS06150	COG1268	BioY protein
CP106_RS06155	COG1122	ATPase activity
CP106_RS06165	COG1842	Phage shock protein A
CP106_RS06170	COG1396	sequence-specific DNA binding
CP106_RS06195	COG1674	ftsk spoiiie
CP106_RS06205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP106_RS06245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP106_RS06255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP106_RS06260	COG0534	Mate efflux family protein
CP106_RS06305	COG3022	response to hydroperoxide
CP106_RS06310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP106_RS06310	COG1648	precorrin-2 dehydrogenase activity
CP106_RS06315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CP106_RS06320	COG0523	cobalamin synthesis protein
CP106_RS06325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP106_RS06325	COG2169	Transcriptional regulator
CP106_RS06390	COG0750	zinc metalloprotease
CP106_RS06450	COG4974	Belongs to the 'phage' integrase family
CP106_RS06485	COG0681	Belongs to the peptidase S26 family
CP106_RS06500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP106_RS06500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP106_RS06500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP106_RS06510	COG0336	Belongs to the RNA methyltransferase TrmD family
CP106_RS06515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP106_RS06535	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP106_RS06565	COG1115	amino acid carrier protein
CP106_RS06570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP106_RS06595	COG0686	Belongs to the AlaDH PNT family
CP106_RS06600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP106_RS06610	COG1929	Belongs to the glycerate kinase type-1 family
CP106_RS06630	COG0058	SHG alpha-glucan phosphorylase activity
CP106_RS06640	COG0469	pyruvate kinase activity
CP106_RS06650	COG0134	indole-3-glycerol-phosphate synthase activity
CP106_RS06670	COG0483	inositol monophosphate 1-phosphatase activity
CP106_RS06760	COG1739	Uncharacterized protein family UPF0029
CP106_RS06765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP106_RS06790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP106_RS06805	COG0252	asparaginase activity
CP106_RS06825	COG3599	regulation of cell shape
CP106_RS06835	COG1799	cell septum assembly
CP106_RS06840	COG1496	oxidoreductase activity
CP106_RS06845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP106_RS06855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP106_RS06885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP106_RS06890	COG0768	penicillin binding
CP106_RS06930	COG0142	geranyltranstransferase activity
CP106_RS06945	COG0515	serine threonine protein kinase
CP106_RS06945	COG2815	serine threonine protein kinase
CP106_RS06950	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP106_RS06970	COG1940	carbohydrate kinase activity
CP106_RS06975	COG0438	transferase activity, transferring glycosyl groups
CP106_RS06985	COG0791	NLP P60 protein
CP106_RS07035	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CP106_RS07040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP106_RS07050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP106_RS07065	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP106_RS07075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP106_RS07075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP106_RS07080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP106_RS07085	COG0509	glycine decarboxylation via glycine cleavage system
CP106_RS07115	COG0174	glutamine synthetase
CP106_RS07150	COG2056	Na+-H+ antiporter family
CP106_RS07160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP106_RS07185	COG0174	glutamine synthetase
CP106_RS07205	COG0557	exoribonuclease II activity
CP106_RS07220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP106_RS07220	COG3323	Protein of unknown function (DUF1653)
CP106_RS07260	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP106_RS07265	COG0596	Alpha beta hydrolase
CP106_RS07290	COG2860	membrane
CP106_RS07360	COG0423	glycine-tRNA ligase activity
CP106_RS07385	COG1381	Involved in DNA repair and RecF pathway recombination
CP106_RS07440	COG1022	Amp-dependent synthetase and ligase
CP106_RS07490	COG1114	Component of the transport system for branched-chain amino acids
CP106_RS07495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP106_RS07505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP106_RS07520	COG0747	negative chemotaxis
CP106_RS07525	COG0601	transmembrane transport
CP106_RS07530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP106_RS07535	COG4172	Belongs to the ABC transporter superfamily
CP106_RS07545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CP106_RS07550	COG2391	methyltransferase activity
CP106_RS07555	COG0601	transmembrane transport
CP106_RS07570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP106_RS07575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP106_RS07595	COG1280	lysine exporter protein (LysE YggA)
CP106_RS07620	COG1307	EDD domain protein, DegV family
CP106_RS07625	COG0406	alpha-ribazole phosphatase activity
CP106_RS07635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP106_RS07650	COG2832	Protein of unknown function (DUF454)
CP106_RS07655	COG0569	domain protein
CP106_RS07655	COG2985	domain, Protein
CP106_RS07680	COG1530	ribonuclease E activity
CP106_RS07695	COG2423	ornithine cyclodeaminase activity
CP106_RS07705	COG0285	dihydrofolate synthase activity
CP106_RS07745	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP106_RS07780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP106_RS07795	COG0668	transmembrane transport
CP106_RS07875	COG1131	(ABC) transporter
CP106_RS07880	COG3336	cytochrome c oxidase
CP106_RS07885	COG1966	Carbon starvation protein
CP106_RS07905	COG0604	alcohol dehydrogenase
CP106_RS07930	COG1376	ErfK ybiS ycfS ynhG family protein
CP106_RS07940	COG2130	NADP-dependent
CP106_RS07945	COG1335	isochorismatase
CP106_RS07990	COG2197	response regulator
CP106_RS08040	COG1234	tRNA 3'-trailer cleavage
CP106_RS08065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CP106_RS08100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP106_RS08110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP106_RS08130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP106_RS08185	COG0033	Phosphoglucomutase
CP106_RS08200	COG0577	efflux transmembrane transporter activity
CP106_RS08200	COG1136	(ABC) transporter
CP106_RS08205	COG1136	(ABC) transporter
CP106_RS08205	COG0577	efflux transmembrane transporter activity
CP106_RS08235	COG2197	response regulator
CP106_RS08245	COG1045	serine acetyltransferase
CP106_RS08265	COG0371	Dehydrogenase
CP106_RS08285	COG1271	oxidase subunit
CP106_RS08290	COG1294	oxidase, subunit
CP106_RS08295	COG4988	ABC transporter
CP106_RS08300	COG4988	ABC transporter
CP106_RS08325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP106_RS08355	COG1597	lipid kinase activity
CP106_RS08370	COG0354	folic acid binding
CP106_RS08395	COG1780	Probably involved in ribonucleotide reductase function
CP106_RS08400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP106_RS08410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP106_RS08415	COG0047	phosphoribosylformylglycinamidine synthase activity
CP106_RS08420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP106_RS08425	COG0386	Belongs to the glutathione peroxidase family
CP106_RS08445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP106_RS08450	COG0569	domain protein
CP106_RS08455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CP106_RS08460	COG0151	Belongs to the GarS family
CP106_RS08465	COG0537	adenosine 5'-monophosphoramidase activity
CP106_RS08475	COG2205	protein histidine kinase activity
CP106_RS08480	COG0745	RESPONSE REGULATOR receiver
CP106_RS08510	COG0028	Belongs to the TPP enzyme family
CP106_RS08555	COG1609	Transcriptional regulator
CP106_RS08565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP106_RS08585	COG1329	Transcriptional regulator
CP106_RS08590	COG2847	Copper chaperone PCu(A)C
CP106_RS08615	COG0288	reversible hydration of carbon dioxide
CP106_RS08640	COG0477	Major facilitator Superfamily
CP106_RS08645	COG1957	nucleoside hydrolase
CP106_RS08660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP106_RS08675	COG1301	dicarboxylic acid transport
CP106_RS08680	COG1012	belongs to the aldehyde dehydrogenase family
CP106_RS08685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP106_RS08690	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CP106_RS08695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP106_RS08725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP106_RS08730	COG0302	gtp cyclohydrolase
CP106_RS08735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP106_RS08740	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CP106_RS08750	COG2027	D-alanyl-D-alanine carboxypeptidase
CP106_RS08755	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP106_RS08760	COG0425	Belongs to the sulfur carrier protein TusA family
CP106_RS08760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP106_RS08765	COG1301	dicarboxylic acid transport
CP106_RS08820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP106_RS08820	COG2111	Na H antiporter
CP106_RS08825	COG1006	Multisubunit Na H antiporter MnhC subunit
CP106_RS08830	COG0651	ATP synthesis coupled electron transport
CP106_RS08850	COG1051	belongs to the nudix hydrolase family
CP106_RS08870	COG0242	peptide deformylase activity
CP106_RS08875	COG0456	acetyltransferase
CP106_RS08885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP106_RS08910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP106_RS08925	COG0280	phosphate acetyltransferase
CP106_RS08945	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CP106_RS08950	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CP106_RS08980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP106_RS08985	COG1333	cytochrome c biogenesis protein
CP106_RS08995	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CP106_RS09000	COG3005	denitrification pathway
CP106_RS09025	COG4129	membrane
CP106_RS09070	COG0191	fructose-bisphosphate aldolase activity
CP106_RS09085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP106_RS09100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP106_RS09185	COG1136	(ABC) transporter
CP106_RS09190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP106_RS09230	COG0789	Transcriptional regulator
CP106_RS09245	COG0443	Heat shock 70 kDa protein
CP106_RS09280	COG0601	transmembrane transport
CP106_RS09300	COG2181	nitrate reductase activity
CP106_RS09300	COG0247	lactate metabolic process
CP106_RS09315	COG1120	ATPase activity
CP106_RS09320	COG4139	cobalamin transport
CP106_RS09330	COG0829	nickel cation binding
CP106_RS09335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP106_RS09340	COG0830	nickel cation binding
CP106_RS09345	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CP106_RS09350	COG0804	urea catabolic process
CP106_RS09355	COG0832	Belongs to the urease beta subunit family
CP106_RS09360	COG0831	urea catabolic process
CP106_RS09380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP106_RS09380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP106_RS09400	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP106_RS09415	COG1012	belongs to the aldehyde dehydrogenase family
CP106_RS09425	COG1472	Belongs to the glycosyl hydrolase 3 family
CP106_RS09435	COG4981	capsule polysaccharide biosynthetic process
CP106_RS09440	COG2755	lipolytic protein G-D-S-L family
CP106_RS09440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP106_RS09450	COG0438	transferase activity, transferring glycosyl groups
CP106_RS09455	COG0500	methyltransferase
CP106_RS09505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP106_RS09510	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CP106_RS09510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP106_RS09510	COG3321	synthase
CP106_RS09515	COG0318	PFAM AMP-dependent synthetase and ligase
CP106_RS09520	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CP106_RS09530	COG5479	isomerase activity
CP106_RS09530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP106_RS09545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP106_RS09550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP106_RS09555	COG0671	phosphoesterase, PA-phosphatase related
CP106_RS09570	COG0671	phosphoesterase, PA-phosphatase related
CP106_RS09580	COG0584	glycerophosphoryl diester phosphodiesterase
CP106_RS09585	COG2271	Major facilitator Superfamily
CP106_RS09600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP106_RS09605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP106_RS09615	COG0561	phosphatase activity
CP106_RS09630	COG2188	Transcriptional regulator
CP106_RS09650	COG0077	Prephenate dehydratase
CP106_RS09655	COG0154	amidase activity
CP106_RS09665	COG1316	TRANSCRIPTIONal
CP106_RS09680	COG1115	amino acid carrier protein
CP106_RS09695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CP106_RS09725	COG0431	NADPH-dependent FMN reductase
CP106_RS09730	COG2814	Major facilitator Superfamily
CP106_RS09775	COG2197	response regulator
CP106_RS09795	COG3764	Sortase (surface protein transpeptidase)
CP106_RS09800	COG0706	membrane insertase activity
CP106_RS09825	COG0564	pseudouridine synthase activity
CP106_RS09850	COG1131	(ABC) transporter
CP106_RS09865	COG1842	Phage shock protein A
CP106_RS09870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP106_RS09885	COG0477	Major facilitator Superfamily
CP106_RS09890	COG0305	Participates in initiation and elongation during chromosome replication
CP106_RS09895	COG3387	PFAM Glycoside hydrolase 15-related
CP106_RS09925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP106_RS09945	COG0300	oxidoreductase activity
CP106_RS09960	COG0586	Pfam SNARE associated Golgi protein
CP106_RS09965	COG0783	Belongs to the Dps family
CP106_RS09970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP106_RS09975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CP106_RS09975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CP106_RS09985	COG1511	domain protein
CP106_RS09995	COG0577	efflux transmembrane transporter activity
CP106_RS09995	COG1136	(ABC) transporter
CP106_RS10015	COG4585	Histidine kinase
CP106_RS10020	COG2197	response regulator
CP106_RS10035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP106_RS10050	COG2186	Transcriptional regulator
CP106_RS10055	COG0747	negative chemotaxis
CP106_RS10060	COG0601	transmembrane transport
CP106_RS10065	COG0444	Belongs to the ABC transporter superfamily
CP106_RS10070	COG4608	Belongs to the ABC transporter superfamily
CP106_RS10075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP106_RS10115	COG3422	double-strand break repair
CP106_RS10130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CP106_RS10150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP106_RS10155	COG0512	Glutamine amidotransferase of anthranilate synthase
CP106_RS10165	COG0134	indole-3-glycerol-phosphate synthase activity
CP106_RS10165	COG0135	phosphoribosylanthranilate isomerase activity
CP106_RS10195	COG1687	branched-chain amino acid
CP106_RS10200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CP106_RS10205	COG1678	Uncharacterized ACR, COG1678
CP106_RS10210	COG0617	tRNA 3'-terminal CCA addition
CP106_RS10245	COG3409	Peptidoglycan-binding domain 1 protein
CP106_RS10245	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP106_RS10255	COG1192	Involved in chromosome partitioning
CP106_RS10270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP106_RS10280	COG0230	Belongs to the bacterial ribosomal protein bL34 family