locus-tag	class	description
CPC231_RS10440	COG0592	DNA-directed DNA polymerase activity
CPC231_RS10455	COG0187	DNA topoisomerase II activity
CPC231_RS10475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPC231_RS10565	COG1120	ATPase activity
CPC231_RS10570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS10575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS10580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPC231_RS10590	COG2815	serine threonine protein kinase
CPC231_RS10590	COG0515	serine threonine protein kinase
CPC231_RS10595	COG0515	serine threonine protein kinase
CPC231_RS10600	COG0768	penicillin binding
CPC231_RS10620	COG1716	ATPase activity
CPC231_RS10620	COG1716	ATPase activity
CPC231_RS10650	COG1120	ATPase activity
CPC231_RS10655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS10660	COG2239	Acts as a magnesium transporter
CPC231_RS10665	COG0366	Alpha amylase catalytic
CPC231_RS10720	COG1125	glycine betaine transport
CPC231_RS10720	COG0517	IMP dehydrogenase activity
CPC231_RS10725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPC231_RS10745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPC231_RS10755	COG3409	Peptidoglycan-binding domain 1 protein
CPC231_RS10755	COG3757	hydrolase, family 25
CPC231_RS10780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CPC231_RS10805	COG1846	Transcriptional regulator
CPC231_RS10820	COG3180	Ammonia monooxygenase
CPC231_RS10830	COG0730	response to heat
CPC231_RS10845	COG1643	Atp-dependent helicase
CPC231_RS10855	COG0519	Catalyzes the synthesis of GMP from XMP
CPC231_RS10865	COG0393	Putative heavy-metal-binding
CPC231_RS10870	COG2501	S4 domain
CPC231_RS10895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPC231_RS10900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CPC231_RS10910	COG3590	peptidase
CPC231_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
CPC231_RS10945	COG0277	FAD linked oxidase domain protein
CPC231_RS10975	COG1216	Glycosyl transferase, family 2
CPC231_RS10985	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPC231_RS10990	COG1121	(ABC) transporter
CPC231_RS10995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPC231_RS11000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPC231_RS11005	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPC231_RS11030	COG0604	alcohol dehydrogenase
CPC231_RS11055	COG0471	metal ion transport
CPC231_RS11070	COG1263	PTS System
CPC231_RS11070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPC231_RS11075	COG2190	(PTS) system
CPC231_RS11075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPC231_RS11075	COG1263	PTS System
CPC231_RS11100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPC231_RS11115	COG0287	Prephenate dehydrogenase
CPC231_RS11135	COG2409	Drug exporters of the RND superfamily
CPC231_RS11140	COG0343	queuine tRNA-ribosyltransferase activity
CPC231_RS11150	COG2610	gluconate transmembrane transporter activity
CPC231_RS11155	COG3265	gluconokinase activity
CPC231_RS11160	COG1063	alcohol dehydrogenase
CPC231_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
CPC231_RS11175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPC231_RS11200	COG2610	gluconate transmembrane transporter activity
CPC231_RS11205	COG2084	Dehydrogenase
CPC231_RS11220	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPC231_RS11225	COG3442	glutamine amidotransferase
CPC231_RS11230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPC231_RS11245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPC231_RS11250	COG2390	Transcriptional regulator
CPC231_RS11255	COG0813	purine-nucleoside phosphorylase activity
CPC231_RS11270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPC231_RS11300	COG0697	spore germination
CPC231_RS11305	COG0527	aspartate kinase activity
CPC231_RS11365	COG1840	ABC-type Fe3 transport system, periplasmic component
CPC231_RS11370	COG2271	Major facilitator Superfamily
CPC231_RS11380	COG3852	Histidine kinase
CPC231_RS11400	COG0651	ATP synthesis coupled electron transport
CPC231_RS11410	COG2111	Na H antiporter
CPC231_RS11410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPC231_RS11470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPC231_RS11490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPC231_RS11510	COG0494	nUDIX hydrolase
CPC231_RS11575	COG1205	dead DEAH box helicase
CPC231_RS11575	COG1111	helicase
CPC231_RS11585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPC231_RS11585	COG1754	DNA topoisomerase type I activity
CPC231_RS11590	COG1297	OPT oligopeptide transporter protein
CPC231_RS11600	COG0470	DNA polymerase III
CPC231_RS11615	COG0318	PFAM AMP-dependent synthetase and ligase
CPC231_RS11625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CPC231_RS11635	COG1088	dTDP-glucose 4,6-dehydratase activity
CPC231_RS11645	COG1505	serine-type exopeptidase activity
CPC231_RS11655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPC231_RS11660	COG3800	Transcriptional regulator
CPC231_RS11660	COG1396	sequence-specific DNA binding
CPC231_RS11670	COG1053	succinate dehydrogenase
CPC231_RS11675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPC231_RS11685	COG2733	membrane
CPC231_RS11695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CPC231_RS11715	COG1882	Formate acetyltransferase
CPC231_RS11735	COG0318	PFAM AMP-dependent synthetase and ligase
CPC231_RS11750	COG5002	protein histidine kinase activity
CPC231_RS11755	COG0745	RESPONSE REGULATOR receiver
CPC231_RS11775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPC231_RS11785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CPC231_RS11785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CPC231_RS11815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CPC231_RS11815	COG1648	precorrin-2 dehydrogenase activity
CPC231_RS11830	COG2217	Heavy metal translocating P-type atpase
CPC231_RS11840	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CPC231_RS11855	COG0406	alpha-ribazole phosphatase activity
CPC231_RS11865	COG0785	Cytochrome C biogenesis protein
CPC231_RS11875	COG0275	rRNA processing
CPC231_RS11890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS11895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPC231_RS11930	COG4948	Mandelate Racemase Muconate Lactonizing
CPC231_RS11945	COG0438	transferase activity, transferring glycosyl groups
CPC231_RS11945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPC231_RS11955	COG0039	L-malate dehydrogenase activity
CPC231_RS11960	COG0644	oxidoreductase
CPC231_RS11965	COG0142	geranyltranstransferase activity
CPC231_RS11990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPC231_RS12015	COG3579	cysteine-type endopeptidase activity
CPC231_RS12020	COG1902	pentaerythritol trinitrate reductase activity
CPC231_RS12040	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPC231_RS12050	COG1121	(ABC) transporter
CPC231_RS12055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPC231_RS12085	COG2197	response regulator
CPC231_RS12110	COG0701	Predicted permease
CPC231_RS12180	COG1302	Protein conserved in bacteria
CPC231_RS12275	COG0814	amino acid
CPC231_RS12280	COG1760	l-serine dehydratase
CPC231_RS12285	COG0252	asparaginase activity
CPC231_RS12290	COG0671	phosphoesterase, PA-phosphatase related
CPC231_RS12335	COG1175	transmembrane transport
CPC231_RS12340	COG3833	ABC-type maltose transport systems, permease component
CPC231_RS12360	COG3842	ATPase activity
CPC231_RS12365	COG0201	protein transport
CPC231_RS12420	COG0203	ribosomal protein L17
CPC231_RS12440	COG1404	Belongs to the peptidase S8 family
CPC231_RS12450	COG1674	ftsk spoiiie
CPC231_RS12505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CPC231_RS12575	COG0516	GMP reductase activity
CPC231_RS12620	COG2011	ABC-type metal ion transport system permease component
CPC231_RS12630	COG1464	Belongs to the NlpA lipoprotein family
CPC231_RS12635	COG1464	Belongs to the NlpA lipoprotein family
CPC231_RS12655	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPC231_RS12660	COG1121	(ABC) transporter
CPC231_RS12670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPC231_RS12670	COG1321	iron dependent repressor
CPC231_RS12675	COG1321	iron dependent repressor
CPC231_RS12680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CPC231_RS12685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CPC231_RS12720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS12725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CPC231_RS12740	COG2838	Isocitrate dehydrogenase
CPC231_RS12745	COG2814	Major facilitator Superfamily
CPC231_RS12750	COG0789	Transcriptional regulator
CPC231_RS12750	COG4978	Transcriptional regulator
CPC231_RS12765	COG0180	Tryptophanyl-tRNA synthetase
CPC231_RS12770	COG1295	ribonuclease BN
CPC231_RS12775	COG1686	Belongs to the peptidase S11 family
CPC231_RS12810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPC231_RS12815	COG1473	amidohydrolase
CPC231_RS12815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CPC231_RS12830	COG2814	Major facilitator Superfamily
CPC231_RS12840	COG4770	biotin carboxylase activity
CPC231_RS12845	COG2897	thiosulfate sulfurtransferase activity
CPC231_RS12850	COG0189	ligase activity
CPC231_RS12855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CPC231_RS12855	COG2755	lipolytic protein G-D-S-L family
CPC231_RS12865	COG0424	maF-like protein
CPC231_RS12870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPC231_RS12875	COG1609	Transcriptional regulator
CPC231_RS12885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPC231_RS12890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPC231_RS12895	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CPC231_RS12895	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CPC231_RS12945	COG1316	TRANSCRIPTIONal
CPC231_RS12955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CPC231_RS12985	COG1482	cell wall glycoprotein biosynthetic process
CPC231_RS13010	COG0745	RESPONSE REGULATOR receiver
CPC231_RS13015	COG5002	protein histidine kinase activity
CPC231_RS13030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CPC231_RS13070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CPC231_RS13075	COG2135	peptidase activity
CPC231_RS13080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPC231_RS13115	COG0513	Belongs to the DEAD box helicase family
CPC231_RS13140	COG0210	DNA helicase
CPC231_RS13150	COG2816	NAD+ diphosphatase activity
CPC231_RS13175	COG3480	Lon protease (S16) C-terminal proteolytic domain
CPC231_RS13290	COG0483	inositol monophosphate 1-phosphatase activity
CPC231_RS13295	COG0483	inositol monophosphate 1-phosphatase activity
CPC231_RS13315	COG2884	Cell division ATP-binding protein ftsE
CPC231_RS13320	COG2177	Part of the ABC transporter FtsEX involved in
CPC231_RS13330	COG0288	reversible hydration of carbon dioxide
CPC231_RS13380	COG1061	Type III restriction enzyme res subunit
CPC231_RS13395	COG1652	LysM domain
CPC231_RS13420	COG2252	PERMEase
CPC231_RS13425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPC231_RS13445	COG0372	Belongs to the citrate synthase family
CPC231_RS13450	COG0545	Peptidyl-prolyl cis-trans isomerase
CPC231_RS13465	COG0656	L-ascorbic acid biosynthetic process
CPC231_RS13470	COG1024	Enoyl-CoA hydratase
CPC231_RS13480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPC231_RS13490	COG3757	hydrolase, family 25
CPC231_RS13505	COG0534	Mate efflux family protein
CPC231_RS13510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPC231_RS13515	COG0019	diaminopimelate decarboxylase activity
CPC231_RS13530	COG4166	transmembrane transport
CPC231_RS13535	COG0601	transmembrane transport
CPC231_RS13545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPC231_RS13565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPC231_RS13580	COG1218	3'(2'),5'-bisphosphate nucleotidase
CPC231_RS13585	COG1201	RNA secondary structure unwinding
CPC231_RS13595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPC231_RS13645	COG1126	abc transporter atp-binding protein
CPC231_RS13650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPC231_RS13655	COG0765	amino acid transport
CPC231_RS13660	COG0765	amino acid transport
CPC231_RS13670	COG1309	transcriptional regulator
CPC231_RS13700	COG0254	rRNA binding
CPC231_RS13710	COG0745	RESPONSE REGULATOR receiver
CPC231_RS13715	COG2205	protein histidine kinase activity
CPC231_RS13720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPC231_RS13725	COG0315	cyclic pyranopterin monophosphate synthase activity
CPC231_RS13725	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPC231_RS13745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPC231_RS13765	COG2259	Doxx family
CPC231_RS13775	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CPC231_RS13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPC231_RS13785	COG3949	Membrane
CPC231_RS13800	COG0084	hydrolase, TatD family'
CPC231_RS13805	COG3583	domain protein
CPC231_RS13820	COG0488	(ABC) transporter
CPC231_RS13835	COG2326	polyphosphate kinase activity
CPC231_RS13870	COG0596	Alpha beta hydrolase
CPC231_RS13875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CPC231_RS13885	COG0193	aminoacyl-tRNA hydrolase activity
CPC231_RS13890	COG2070	2-Nitropropane dioxygenase
CPC231_RS13910	COG1523	belongs to the glycosyl hydrolase 13 family
CPC231_RS13915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPC231_RS13920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CPC231_RS13925	COG2132	Multicopper oxidase
CPC231_RS13940	COG1309	transcriptional regulator
CPC231_RS13950	COG0531	amino acid
CPC231_RS13955	COG3956	TIGRFAM MazG family protein
CPC231_RS14015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CPC231_RS14085	COG0114	fumarate hydratase activity
CPC231_RS14090	COG1494	fructose-1,6-bisphosphatase
CPC231_RS14125	COG0012	GTP binding
CPC231_RS14140	COG2824	Alkylphosphonate utilization operon protein PhnA
CPC231_RS14145	COG1132	(ABC) transporter
CPC231_RS14160	COG2354	Protein conserved in bacteria
CPC231_RS14170	COG4721	ABC-type cobalt transport system, permease component
CPC231_RS14175	COG1122	ATPase activity
CPC231_RS14185	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CPC231_RS14195	COG4166	transmembrane transport
CPC231_RS14200	COG0601	transmembrane transport
CPC231_RS14205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPC231_RS14235	COG1217	gtp-binding protein TYPA
CPC231_RS14240	COG4166	transmembrane transport
CPC231_RS14275	COG1113	amino acid transport
CPC231_RS14285	COG1113	amino acid transport
CPC231_RS14295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPC231_RS14300	COG1611	Belongs to the LOG family
CPC231_RS14305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPC231_RS14310	COG0463	Glycosyl transferase, family 2
CPC231_RS14330	COG3527	Alpha-acetolactate decarboxylase
CPC231_RS14335	COG0297	glycogen (starch) synthase activity
CPC231_RS14345	COG4122	O-methyltransferase activity
CPC231_RS14375	COG2239	Acts as a magnesium transporter
CPC231_RS14385	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPC231_RS14385	COG0567	Dehydrogenase, E1 component
CPC231_RS14390	COG1132	(ABC) transporter
CPC231_RS14400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPC231_RS14405	COG2272	Belongs to the type-B carboxylesterase lipase family
CPC231_RS14420	COG2017	converts alpha-aldose to the beta-anomer
CPC231_RS14440	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CPC231_RS14470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPC231_RS14475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CPC231_RS14500	COG1846	Transcriptional regulator
CPC231_RS14530	COG1556	Lactate utilization protein
CPC231_RS14535	COG1139	Iron-sulfur cluster binding protein
CPC231_RS14540	COG0247	lactate metabolic process
CPC231_RS14545	COG1620	l-lactate permease
CPC231_RS14555	COG0019	diaminopimelate decarboxylase activity
CPC231_RS14560	COG0460	homoserine dehydrogenase
CPC231_RS14610	COG0356	it plays a direct role in the translocation of protons across the membrane
CPC231_RS14615	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPC231_RS14620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CPC231_RS14660	COG0346	lactoylglutathione lyase activity
CPC231_RS14685	COG1119	ATPase activity
CPC231_RS14705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CPC231_RS14770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS14775	COG1120	ATPase activity
CPC231_RS14785	COG0205	6-phosphofructokinase activity
CPC231_RS14795	COG0667	Aldo Keto reductase
CPC231_RS14805	COG0583	DNA-binding transcription factor activity
CPC231_RS14830	COG0668	transmembrane transport
CPC231_RS14870	COG0473	3-isopropylmalate dehydrogenase activity
CPC231_RS14890	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPC231_RS14920	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CPC231_RS14955	COG0406	alpha-ribazole phosphatase activity
CPC231_RS14955	COG0494	nUDIX hydrolase
CPC231_RS14975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CPC231_RS14980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CPC231_RS14985	COG1461	Dihydroxyacetone kinase
CPC231_RS14995	COG0511	ligase activity, forming carbon-carbon bonds
CPC231_RS15000	COG0742	ribosomal rna small subunit methyltransferase
CPC231_RS15025	COG0765	amino acid transport
CPC231_RS15050	COG2226	methyltransferase
CPC231_RS15055	COG0539	negative regulation of cytoplasmic translation
CPC231_RS15065	COG0237	dephospho-CoA kinase activity
CPC231_RS15095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPC231_RS15110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPC231_RS15125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPC231_RS15140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CPC231_RS15155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CPC231_RS15175	COG0165	Argininosuccinate lyase
CPC231_RS15180	COG2835	tetraacyldisaccharide 4'-kinase activity
CPC231_RS15210	COG0647	UMP catabolic process
CPC231_RS15240	COG0494	nUDIX hydrolase
CPC231_RS15245	COG4974	Belongs to the 'phage' integrase family
CPC231_RS15265	COG3104	oligopeptide transport
CPC231_RS15270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CPC231_RS15280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CPC231_RS15295	COG1160	GTP binding
CPC231_RS15300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPC231_RS15305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CPC231_RS15310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CPC231_RS15315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CPC231_RS15320	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CPC231_RS15325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS15330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS15335	COG1120	ATPase activity
CPC231_RS15340	COG4264	IucA IucC family
CPC231_RS15370	COG0653	protein targeting
CPC231_RS15410	COG1253	flavin adenine dinucleotide binding
CPC231_RS15415	COG0513	Belongs to the DEAD box helicase family
CPC231_RS15420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CPC231_RS15430	COG0598	Magnesium transport protein CorA
CPC231_RS15450	COG0477	Major facilitator Superfamily
CPC231_RS15475	COG0463	Glycosyl transferase, family 2
CPC231_RS15525	COG0300	oxidoreductase activity
CPC231_RS15540	COG0805	protein transport
CPC231_RS15550	COG2378	regulation of single-species biofilm formation
CPC231_RS15570	COG4122	O-methyltransferase activity
CPC231_RS15585	COG1362	aminopeptidase activity
CPC231_RS15605	COG1027	Aspartate ammonia-lyase
CPC231_RS15610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPC231_RS15630	COG1410	methionine synthase
CPC231_RS15630	COG0646	methionine synthase
CPC231_RS15650	COG0667	Aldo Keto reductase
CPC231_RS15660	COG0167	dihydroorotate dehydrogenase activity
CPC231_RS15685	COG1461	Dihydroxyacetone kinase
CPC231_RS15690	COG2376	Dihydroxyacetone kinase
CPC231_RS15700	COG0488	(ABC) transporter
CPC231_RS15765	COG0791	NLP P60 protein
CPC231_RS15765	COG3883	PFAM NLP P60 protein
CPC231_RS15795	COG2848	UPF0210 protein
CPC231_RS15820	COG2151	metal-sulfur cluster biosynthetic enzyme
CPC231_RS15825	COG0822	iron-sulfur transferase activity
CPC231_RS15835	COG0396	ATPase activity
CPC231_RS15880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPC231_RS15885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPC231_RS15905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPC231_RS15925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPC231_RS15935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CPC231_RS15945	COG0322	excinuclease ABC activity
CPC231_RS15975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPC231_RS15990	COG0242	peptide deformylase activity
CPC231_RS16030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPC231_RS16040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CPC231_RS16055	COG1090	epimerase
CPC231_RS16080	COG0006	proline dipeptidase activity
CPC231_RS16085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CPC231_RS16090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CPC231_RS16095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPC231_RS16100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CPC231_RS16120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPC231_RS16175	COG1760	l-serine dehydratase
CPC231_RS16200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPC231_RS16205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPC231_RS16220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPC231_RS16235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPC231_RS16240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPC231_RS16270	COG1946	Acyl-CoA thioesterase
CPC231_RS16285	COG0156	8-amino-7-oxononanoate synthase activity
CPC231_RS16300	COG1560	Kdo2-lipid A biosynthetic process
CPC231_RS16305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CPC231_RS16320	COG2837	iron assimilation
CPC231_RS16370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPC231_RS16375	COG3253	May function as heme-dependent peroxidase
CPC231_RS16460	COG2890	protein-(glutamine-N5) methyltransferase activity
CPC231_RS16500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CPC231_RS16505	COG0450	alkyl hydroperoxide reductase
CPC231_RS16520	COG1643	Atp-dependent helicase
CPC231_RS16540	COG1349	DNA-binding transcription factor activity
CPC231_RS16545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPC231_RS16550	COG1349	DNA-binding transcription factor activity
CPC231_RS16555	COG1105	Belongs to the carbohydrate kinase PfkB family
CPC231_RS16560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPC231_RS16560	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CPC231_RS16560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPC231_RS16565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPC231_RS16570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPC231_RS16580	COG2233	PERMEase
CPC231_RS16585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPC231_RS16600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPC231_RS16615	COG1196	nuclear chromosome segregation
CPC231_RS16635	COG2137	regulation of response to DNA damage stimulus
CPC231_RS16640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPC231_RS16650	COG1268	BioY protein
CPC231_RS16655	COG1122	ATPase activity
CPC231_RS16665	COG1842	Phage shock protein A
CPC231_RS16670	COG1396	sequence-specific DNA binding
CPC231_RS16695	COG1674	ftsk spoiiie
CPC231_RS16705	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPC231_RS16745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CPC231_RS16755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CPC231_RS16760	COG0534	Mate efflux family protein
CPC231_RS16805	COG3022	response to hydroperoxide
CPC231_RS16810	COG1648	precorrin-2 dehydrogenase activity
CPC231_RS16810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CPC231_RS16815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CPC231_RS16820	COG0523	cobalamin synthesis protein
CPC231_RS16825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPC231_RS16825	COG2169	Transcriptional regulator
CPC231_RS16890	COG0750	zinc metalloprotease
CPC231_RS16945	COG4974	Belongs to the 'phage' integrase family
CPC231_RS16970	COG0681	Belongs to the peptidase S26 family
CPC231_RS16985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPC231_RS16985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPC231_RS16985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPC231_RS16995	COG0336	Belongs to the RNA methyltransferase TrmD family
CPC231_RS17000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CPC231_RS17020	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CPC231_RS17050	COG1115	amino acid carrier protein
CPC231_RS17055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPC231_RS17080	COG0686	Belongs to the AlaDH PNT family
CPC231_RS17085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CPC231_RS17090	COG1929	Belongs to the glycerate kinase type-1 family
CPC231_RS17110	COG0058	SHG alpha-glucan phosphorylase activity
CPC231_RS17120	COG0469	pyruvate kinase activity
CPC231_RS17130	COG0134	indole-3-glycerol-phosphate synthase activity
CPC231_RS17150	COG0483	inositol monophosphate 1-phosphatase activity
CPC231_RS17215	COG2176	DNA-directed DNA polymerase activity
CPC231_RS17240	COG1739	Uncharacterized protein family UPF0029
CPC231_RS17245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPC231_RS17270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPC231_RS17285	COG0252	asparaginase activity
CPC231_RS17305	COG3599	regulation of cell shape
CPC231_RS17315	COG1799	cell septum assembly
CPC231_RS17320	COG1496	oxidoreductase activity
CPC231_RS17325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPC231_RS17335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPC231_RS17365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPC231_RS17370	COG0768	penicillin binding
CPC231_RS17410	COG0142	geranyltranstransferase activity
CPC231_RS17425	COG0515	serine threonine protein kinase
CPC231_RS17425	COG2815	serine threonine protein kinase
CPC231_RS17430	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CPC231_RS17450	COG1940	carbohydrate kinase activity
CPC231_RS17455	COG0438	transferase activity, transferring glycosyl groups
CPC231_RS17465	COG0791	NLP P60 protein
CPC231_RS17515	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CPC231_RS17520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CPC231_RS17530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPC231_RS17545	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPC231_RS17550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPC231_RS17550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPC231_RS17555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CPC231_RS17560	COG0509	glycine decarboxylation via glycine cleavage system
CPC231_RS17590	COG0174	glutamine synthetase
CPC231_RS17740	COG2056	Na+-H+ antiporter family
CPC231_RS17750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CPC231_RS17775	COG0174	glutamine synthetase
CPC231_RS17800	COG0557	exoribonuclease II activity
CPC231_RS17815	COG3323	Protein of unknown function (DUF1653)
CPC231_RS17815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPC231_RS17855	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CPC231_RS17860	COG0596	Alpha beta hydrolase
CPC231_RS17885	COG2860	membrane
CPC231_RS17955	COG0423	glycine-tRNA ligase activity
CPC231_RS17980	COG1381	Involved in DNA repair and RecF pathway recombination
CPC231_RS18035	COG1022	Amp-dependent synthetase and ligase
CPC231_RS18085	COG1114	Component of the transport system for branched-chain amino acids
CPC231_RS18090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPC231_RS18100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPC231_RS18115	COG0747	negative chemotaxis
CPC231_RS18120	COG0601	transmembrane transport
CPC231_RS18125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPC231_RS18130	COG4172	Belongs to the ABC transporter superfamily
CPC231_RS18140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPC231_RS18145	COG2391	methyltransferase activity
CPC231_RS18170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPC231_RS18175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPC231_RS18200	COG1280	lysine exporter protein (LysE YggA)
CPC231_RS18225	COG1307	EDD domain protein, DegV family
CPC231_RS18230	COG0406	alpha-ribazole phosphatase activity
CPC231_RS18240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CPC231_RS18255	COG2832	Protein of unknown function (DUF454)
CPC231_RS18260	COG0569	domain protein
CPC231_RS18260	COG2985	domain, Protein
CPC231_RS18285	COG1530	ribonuclease E activity
CPC231_RS18300	COG2423	ornithine cyclodeaminase activity
CPC231_RS18310	COG0285	dihydrofolate synthase activity
CPC231_RS18350	COG0544	peptidyl-prolyl cis-trans isomerase activity
CPC231_RS18385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CPC231_RS18400	COG0668	transmembrane transport
CPC231_RS18475	COG1131	(ABC) transporter
CPC231_RS18480	COG3336	cytochrome c oxidase
CPC231_RS18485	COG1966	Carbon starvation protein
CPC231_RS18505	COG0604	alcohol dehydrogenase
CPC231_RS18530	COG1376	ErfK ybiS ycfS ynhG family protein
CPC231_RS18540	COG2130	NADP-dependent
CPC231_RS18545	COG1335	isochorismatase
CPC231_RS18590	COG2197	response regulator
CPC231_RS18640	COG1234	tRNA 3'-trailer cleavage
CPC231_RS18665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CPC231_RS18715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPC231_RS18725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPC231_RS18745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPC231_RS18810	COG2197	response regulator
CPC231_RS18825	COG1045	serine acetyltransferase
CPC231_RS18845	COG0371	Dehydrogenase
CPC231_RS18865	COG1271	oxidase subunit
CPC231_RS18870	COG1294	oxidase, subunit
CPC231_RS18875	COG4988	ABC transporter
CPC231_RS18880	COG1132	(ABC) transporter
CPC231_RS18905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CPC231_RS18935	COG1597	lipid kinase activity
CPC231_RS18950	COG0354	folic acid binding
CPC231_RS18975	COG1780	Probably involved in ribonucleotide reductase function
CPC231_RS18980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPC231_RS18990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPC231_RS18995	COG0047	phosphoribosylformylglycinamidine synthase activity
CPC231_RS19000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPC231_RS19005	COG0386	Belongs to the glutathione peroxidase family
CPC231_RS19025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPC231_RS19030	COG0569	domain protein
CPC231_RS19035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPC231_RS19040	COG0151	Belongs to the GarS family
CPC231_RS19045	COG0537	adenosine 5'-monophosphoramidase activity
CPC231_RS19055	COG2205	protein histidine kinase activity
CPC231_RS19060	COG0745	RESPONSE REGULATOR receiver
CPC231_RS19090	COG0028	Belongs to the TPP enzyme family
CPC231_RS19130	COG1609	Transcriptional regulator
CPC231_RS19140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPC231_RS19160	COG1329	Transcriptional regulator
CPC231_RS19165	COG2847	Copper chaperone PCu(A)C
CPC231_RS19180	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPC231_RS19190	COG0288	reversible hydration of carbon dioxide
CPC231_RS19205	COG0542	response to heat
CPC231_RS19215	COG0477	Major facilitator Superfamily
CPC231_RS19220	COG1957	nucleoside hydrolase
CPC231_RS19235	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPC231_RS19250	COG1301	dicarboxylic acid transport
CPC231_RS19255	COG1012	belongs to the aldehyde dehydrogenase family
CPC231_RS19265	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CPC231_RS19270	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CPC231_RS19300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPC231_RS19305	COG0302	gtp cyclohydrolase
CPC231_RS19310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPC231_RS19315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CPC231_RS19325	COG2027	D-alanyl-D-alanine carboxypeptidase
CPC231_RS19330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CPC231_RS19335	COG0425	Belongs to the sulfur carrier protein TusA family
CPC231_RS19335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPC231_RS19340	COG1301	dicarboxylic acid transport
CPC231_RS19355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPC231_RS19360	COG2326	polyphosphate kinase activity
CPC231_RS19400	COG2111	Na H antiporter
CPC231_RS19400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPC231_RS19405	COG1006	Multisubunit Na H antiporter MnhC subunit
CPC231_RS19410	COG0651	ATP synthesis coupled electron transport
CPC231_RS19430	COG1051	belongs to the nudix hydrolase family
CPC231_RS19450	COG0242	peptide deformylase activity
CPC231_RS19455	COG0456	acetyltransferase
CPC231_RS19465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPC231_RS19490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPC231_RS19505	COG0280	phosphate acetyltransferase
CPC231_RS19525	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CPC231_RS19530	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CPC231_RS19560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPC231_RS19565	COG1333	cytochrome c biogenesis protein
CPC231_RS19575	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CPC231_RS19580	COG3005	denitrification pathway
CPC231_RS19595	COG4129	membrane
CPC231_RS19605	COG4129	membrane
CPC231_RS19640	COG0191	fructose-bisphosphate aldolase activity
CPC231_RS19655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPC231_RS19670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CPC231_RS19710	COG1131	(ABC) transporter
CPC231_RS19740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CPC231_RS19760	COG0577	efflux transmembrane transporter activity
CPC231_RS19760	COG1136	(ABC) transporter
CPC231_RS19765	COG1136	(ABC) transporter
CPC231_RS19770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPC231_RS19810	COG0789	Transcriptional regulator
CPC231_RS19825	COG0443	Heat shock 70 kDa protein
CPC231_RS19860	COG0601	transmembrane transport
CPC231_RS19880	COG2181	nitrate reductase activity
CPC231_RS19880	COG0247	lactate metabolic process
CPC231_RS19895	COG1120	ATPase activity
CPC231_RS19900	COG4139	cobalamin transport
CPC231_RS19910	COG0829	nickel cation binding
CPC231_RS19915	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CPC231_RS19920	COG0830	nickel cation binding
CPC231_RS19925	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CPC231_RS19930	COG0804	urea catabolic process
CPC231_RS19935	COG0832	Belongs to the urease beta subunit family
CPC231_RS19940	COG0831	urea catabolic process
CPC231_RS19960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPC231_RS19960	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CPC231_RS19995	COG1012	belongs to the aldehyde dehydrogenase family
CPC231_RS20005	COG1472	Belongs to the glycosyl hydrolase 3 family
CPC231_RS20015	COG4981	capsule polysaccharide biosynthetic process
CPC231_RS20020	COG2755	lipolytic protein G-D-S-L family
CPC231_RS20020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CPC231_RS20030	COG0438	transferase activity, transferring glycosyl groups
CPC231_RS20075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPC231_RS20080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPC231_RS20080	COG3321	synthase
CPC231_RS20080	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CPC231_RS20085	COG0318	PFAM AMP-dependent synthetase and ligase
CPC231_RS20090	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CPC231_RS20100	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CPC231_RS20100	COG5479	isomerase activity
CPC231_RS20115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CPC231_RS20120	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CPC231_RS20125	COG0671	phosphoesterase, PA-phosphatase related
CPC231_RS20130	COG1216	Glycosyl transferase, family 2
CPC231_RS20140	COG0671	phosphoesterase, PA-phosphatase related
CPC231_RS20150	COG0584	glycerophosphoryl diester phosphodiesterase
CPC231_RS20155	COG2271	Major facilitator Superfamily
CPC231_RS20170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPC231_RS20175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPC231_RS20185	COG0561	phosphatase activity
CPC231_RS20200	COG2188	Transcriptional regulator
CPC231_RS20220	COG0077	Prephenate dehydratase
CPC231_RS20225	COG0154	amidase activity
CPC231_RS20235	COG1316	TRANSCRIPTIONal
CPC231_RS20265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPC231_RS20295	COG0431	NADPH-dependent FMN reductase
CPC231_RS20300	COG2814	Major facilitator Superfamily
CPC231_RS20325	COG5650	phosphatidylinositol metabolic process
CPC231_RS20345	COG2197	response regulator
CPC231_RS20365	COG3764	Sortase (surface protein transpeptidase)
CPC231_RS20370	COG0706	membrane insertase activity
CPC231_RS20395	COG0564	pseudouridine synthase activity
CPC231_RS20420	COG1131	(ABC) transporter
CPC231_RS20435	COG1842	Phage shock protein A
CPC231_RS20440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPC231_RS20455	COG0477	Major facilitator Superfamily
CPC231_RS20460	COG0305	Participates in initiation and elongation during chromosome replication
CPC231_RS20465	COG3387	PFAM Glycoside hydrolase 15-related
CPC231_RS20475	COG0629	single-stranded DNA binding
CPC231_RS20495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPC231_RS20515	COG0300	oxidoreductase activity
CPC231_RS20530	COG0586	Pfam SNARE associated Golgi protein
CPC231_RS20535	COG0783	Belongs to the Dps family
CPC231_RS20540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPC231_RS20545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPC231_RS20545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPC231_RS20555	COG1511	domain protein
CPC231_RS20565	COG1136	(ABC) transporter
CPC231_RS20565	COG0577	efflux transmembrane transporter activity
CPC231_RS20585	COG4585	Histidine kinase
CPC231_RS20590	COG2197	response regulator
CPC231_RS20605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPC231_RS20620	COG2186	Transcriptional regulator
CPC231_RS20625	COG0747	negative chemotaxis
CPC231_RS20630	COG0601	transmembrane transport
CPC231_RS20635	COG0444	Belongs to the ABC transporter superfamily
CPC231_RS20640	COG4608	Belongs to the ABC transporter superfamily
CPC231_RS20645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPC231_RS20685	COG3422	double-strand break repair
CPC231_RS20700	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CPC231_RS20720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPC231_RS20725	COG0512	Glutamine amidotransferase of anthranilate synthase
CPC231_RS20735	COG0135	phosphoribosylanthranilate isomerase activity
CPC231_RS20735	COG0134	indole-3-glycerol-phosphate synthase activity
CPC231_RS20770	COG1687	branched-chain amino acid
CPC231_RS20775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CPC231_RS20780	COG1678	Uncharacterized ACR, COG1678
CPC231_RS20785	COG0617	tRNA 3'-terminal CCA addition
CPC231_RS20820	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPC231_RS20820	COG3409	Peptidoglycan-binding domain 1 protein
CPC231_RS20835	COG1192	Involved in chromosome partitioning
CPC231_RS20850	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CPC231_RS20860	COG0230	Belongs to the bacterial ribosomal protein bL34 family