locus-tag	class	description
CPI37_RS00015	COG0592	DNA-directed DNA polymerase activity
CPI37_RS00030	COG0187	DNA topoisomerase II activity
CPI37_RS00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPI37_RS00150	COG1518	maintenance of DNA repeat elements
CPI37_RS00195	COG1120	ATPase activity
CPI37_RS00200	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS00205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS00210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPI37_RS00220	COG0515	serine threonine protein kinase
CPI37_RS00220	COG2815	serine threonine protein kinase
CPI37_RS00225	COG0515	serine threonine protein kinase
CPI37_RS00230	COG0768	penicillin binding
CPI37_RS00250	COG1716	ATPase activity
CPI37_RS00250	COG1716	ATPase activity
CPI37_RS00280	COG1120	ATPase activity
CPI37_RS00285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS00290	COG2239	Acts as a magnesium transporter
CPI37_RS00295	COG0366	Alpha amylase catalytic
CPI37_RS00350	COG0517	IMP dehydrogenase activity
CPI37_RS00350	COG1125	glycine betaine transport
CPI37_RS00365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPI37_RS00385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPI37_RS00395	COG3757	hydrolase, family 25
CPI37_RS00395	COG3409	Peptidoglycan-binding domain 1 protein
CPI37_RS00420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CPI37_RS00445	COG1846	Transcriptional regulator
CPI37_RS00480	COG0730	response to heat
CPI37_RS00495	COG1643	Atp-dependent helicase
CPI37_RS00505	COG0519	Catalyzes the synthesis of GMP from XMP
CPI37_RS00515	COG0393	Putative heavy-metal-binding
CPI37_RS00520	COG2501	S4 domain
CPI37_RS00540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPI37_RS00545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CPI37_RS00555	COG3590	peptidase
CPI37_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
CPI37_RS00590	COG0277	FAD linked oxidase domain protein
CPI37_RS00620	COG1216	Glycosyl transferase, family 2
CPI37_RS00625	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPI37_RS00630	COG1121	(ABC) transporter
CPI37_RS00635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPI37_RS00640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPI37_RS00645	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPI37_RS00670	COG0604	alcohol dehydrogenase
CPI37_RS00705	COG0393	Putative heavy-metal-binding
CPI37_RS00740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPI37_RS00740	COG1263	PTS System
CPI37_RS00745	COG2190	(PTS) system
CPI37_RS00745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPI37_RS00745	COG1263	PTS System
CPI37_RS00770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPI37_RS00785	COG0287	Prephenate dehydrogenase
CPI37_RS00795	COG0590	tRNA wobble adenosine to inosine editing
CPI37_RS00795	COG0037	tRNA processing
CPI37_RS00805	COG2409	Drug exporters of the RND superfamily
CPI37_RS00810	COG0343	queuine tRNA-ribosyltransferase activity
CPI37_RS00820	COG2610	gluconate transmembrane transporter activity
CPI37_RS00825	COG3265	gluconokinase activity
CPI37_RS00830	COG1063	alcohol dehydrogenase
CPI37_RS00850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPI37_RS00875	COG2610	gluconate transmembrane transporter activity
CPI37_RS00880	COG2084	Dehydrogenase
CPI37_RS00895	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPI37_RS00905	COG3442	glutamine amidotransferase
CPI37_RS00910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPI37_RS00920	COG0778	Nitroreductase
CPI37_RS00925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPI37_RS00930	COG2390	Transcriptional regulator
CPI37_RS00935	COG0813	purine-nucleoside phosphorylase activity
CPI37_RS00950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPI37_RS00980	COG0697	spore germination
CPI37_RS00985	COG0527	aspartate kinase activity
CPI37_RS01040	COG1840	ABC-type Fe3 transport system, periplasmic component
CPI37_RS01045	COG2271	Major facilitator Superfamily
CPI37_RS01075	COG0651	ATP synthesis coupled electron transport
CPI37_RS01085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPI37_RS01085	COG2111	Na H antiporter
CPI37_RS01115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPI37_RS01135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPI37_RS01155	COG0494	nUDIX hydrolase
CPI37_RS01235	COG1754	DNA topoisomerase type I activity
CPI37_RS01235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPI37_RS01240	COG1297	OPT oligopeptide transporter protein
CPI37_RS01250	COG0470	DNA polymerase III
CPI37_RS01265	COG0318	PFAM AMP-dependent synthetase and ligase
CPI37_RS01275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CPI37_RS01285	COG1088	dTDP-glucose 4,6-dehydratase activity
CPI37_RS01295	COG1505	serine-type exopeptidase activity
CPI37_RS01310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPI37_RS01315	COG1396	sequence-specific DNA binding
CPI37_RS01315	COG3800	Transcriptional regulator
CPI37_RS01325	COG1053	succinate dehydrogenase
CPI37_RS01330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPI37_RS01340	COG2733	membrane
CPI37_RS01350	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CPI37_RS01370	COG1882	Formate acetyltransferase
CPI37_RS01390	COG0318	PFAM AMP-dependent synthetase and ligase
CPI37_RS01405	COG5002	protein histidine kinase activity
CPI37_RS01410	COG0745	RESPONSE REGULATOR receiver
CPI37_RS01430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPI37_RS01450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CPI37_RS01450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CPI37_RS01480	COG1648	precorrin-2 dehydrogenase activity
CPI37_RS01480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CPI37_RS01495	COG2217	Heavy metal translocating P-type atpase
CPI37_RS01505	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CPI37_RS01520	COG0406	alpha-ribazole phosphatase activity
CPI37_RS01530	COG0785	Cytochrome C biogenesis protein
CPI37_RS01540	COG0275	rRNA processing
CPI37_RS01555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS01560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPI37_RS01595	COG4948	Mandelate Racemase Muconate Lactonizing
CPI37_RS01620	COG0039	L-malate dehydrogenase activity
CPI37_RS01625	COG0644	oxidoreductase
CPI37_RS01630	COG0142	geranyltranstransferase activity
CPI37_RS01655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPI37_RS01680	COG3579	cysteine-type endopeptidase activity
CPI37_RS01685	COG1902	pentaerythritol trinitrate reductase activity
CPI37_RS01705	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPI37_RS01715	COG1121	(ABC) transporter
CPI37_RS01720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPI37_RS01750	COG2197	response regulator
CPI37_RS01755	COG1131	(ABC) transporter
CPI37_RS01770	COG0701	Predicted permease
CPI37_RS01840	COG1302	Protein conserved in bacteria
CPI37_RS01935	COG0814	amino acid
CPI37_RS01940	COG1760	l-serine dehydratase
CPI37_RS01945	COG0252	asparaginase activity
CPI37_RS01985	COG1140	nitrate reductase beta subunit
CPI37_RS02010	COG0746	molybdenum cofactor guanylyltransferase activity
CPI37_RS02015	COG0315	cyclic pyranopterin monophosphate synthase activity
CPI37_RS02025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CPI37_RS02075	COG1175	transmembrane transport
CPI37_RS02080	COG3833	ABC-type maltose transport systems, permease component
CPI37_RS02100	COG3842	ATPase activity
CPI37_RS02105	COG0201	protein transport
CPI37_RS02155	COG0203	ribosomal protein L17
CPI37_RS02175	COG1404	Belongs to the peptidase S8 family
CPI37_RS02185	COG1674	ftsk spoiiie
CPI37_RS02240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CPI37_RS02315	COG0516	GMP reductase activity
CPI37_RS02360	COG2011	ABC-type metal ion transport system permease component
CPI37_RS02370	COG1464	Belongs to the NlpA lipoprotein family
CPI37_RS02380	COG1464	Belongs to the NlpA lipoprotein family
CPI37_RS02395	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPI37_RS02400	COG1121	(ABC) transporter
CPI37_RS02410	COG1321	iron dependent repressor
CPI37_RS02410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPI37_RS02415	COG1321	iron dependent repressor
CPI37_RS02420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CPI37_RS02425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CPI37_RS02465	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CPI37_RS02475	COG2873	o-acetylhomoserine
CPI37_RS02480	COG2838	Isocitrate dehydrogenase
CPI37_RS02485	COG2814	Major facilitator Superfamily
CPI37_RS02490	COG4978	Transcriptional regulator
CPI37_RS02490	COG0789	Transcriptional regulator
CPI37_RS02505	COG0180	Tryptophanyl-tRNA synthetase
CPI37_RS02510	COG1295	ribonuclease BN
CPI37_RS02515	COG1686	Belongs to the peptidase S11 family
CPI37_RS02550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPI37_RS02555	COG1473	amidohydrolase
CPI37_RS02555	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CPI37_RS02570	COG2814	Major facilitator Superfamily
CPI37_RS02580	COG4770	biotin carboxylase activity
CPI37_RS02585	COG2897	thiosulfate sulfurtransferase activity
CPI37_RS02590	COG0189	ligase activity
CPI37_RS02595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CPI37_RS02595	COG2755	lipolytic protein G-D-S-L family
CPI37_RS02605	COG0424	maF-like protein
CPI37_RS02610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPI37_RS02615	COG1609	Transcriptional regulator
CPI37_RS02625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPI37_RS02630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPI37_RS02635	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CPI37_RS02635	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CPI37_RS02685	COG1316	TRANSCRIPTIONal
CPI37_RS02695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CPI37_RS02730	COG1482	cell wall glycoprotein biosynthetic process
CPI37_RS02760	COG0745	RESPONSE REGULATOR receiver
CPI37_RS02765	COG5002	protein histidine kinase activity
CPI37_RS02780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CPI37_RS02820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CPI37_RS02825	COG2135	peptidase activity
CPI37_RS02830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPI37_RS02865	COG0513	Belongs to the DEAD box helicase family
CPI37_RS02900	COG2816	NAD+ diphosphatase activity
CPI37_RS02925	COG3480	Lon protease (S16) C-terminal proteolytic domain
CPI37_RS03040	COG0483	inositol monophosphate 1-phosphatase activity
CPI37_RS03045	COG0483	inositol monophosphate 1-phosphatase activity
CPI37_RS03060	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CPI37_RS03070	COG2884	Cell division ATP-binding protein ftsE
CPI37_RS03075	COG2177	Part of the ABC transporter FtsEX involved in
CPI37_RS03095	COG0288	reversible hydration of carbon dioxide
CPI37_RS03175	COG0012	GTP binding
CPI37_RS03190	COG2824	Alkylphosphonate utilization operon protein PhnA
CPI37_RS03195	COG1132	(ABC) transporter
CPI37_RS03200	COG1132	(ABC) transporter
CPI37_RS03210	COG2354	Protein conserved in bacteria
CPI37_RS03220	COG4721	ABC-type cobalt transport system, permease component
CPI37_RS03225	COG1122	ATPase activity
CPI37_RS03245	COG4166	transmembrane transport
CPI37_RS03250	COG0601	transmembrane transport
CPI37_RS03255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPI37_RS03285	COG1217	gtp-binding protein TYPA
CPI37_RS03290	COG4166	transmembrane transport
CPI37_RS03325	COG1113	amino acid transport
CPI37_RS03335	COG1113	amino acid transport
CPI37_RS03345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPI37_RS03350	COG1611	Belongs to the LOG family
CPI37_RS03355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPI37_RS03360	COG0463	Glycosyl transferase, family 2
CPI37_RS03385	COG3527	Alpha-acetolactate decarboxylase
CPI37_RS03390	COG0297	glycogen (starch) synthase activity
CPI37_RS03400	COG4122	O-methyltransferase activity
CPI37_RS03430	COG2239	Acts as a magnesium transporter
CPI37_RS03440	COG0567	Dehydrogenase, E1 component
CPI37_RS03440	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPI37_RS03445	COG1132	(ABC) transporter
CPI37_RS03455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPI37_RS03460	COG2272	Belongs to the type-B carboxylesterase lipase family
CPI37_RS03480	COG2017	converts alpha-aldose to the beta-anomer
CPI37_RS03500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CPI37_RS03535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CPI37_RS03560	COG1846	Transcriptional regulator
CPI37_RS03575	COG1349	DNA-binding transcription factor activity
CPI37_RS03590	COG1556	Lactate utilization protein
CPI37_RS03595	COG1139	Iron-sulfur cluster binding protein
CPI37_RS03600	COG0247	lactate metabolic process
CPI37_RS03605	COG1620	l-lactate permease
CPI37_RS03615	COG0019	diaminopimelate decarboxylase activity
CPI37_RS03620	COG0460	homoserine dehydrogenase
CPI37_RS03670	COG0356	it plays a direct role in the translocation of protons across the membrane
CPI37_RS03675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPI37_RS03680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CPI37_RS03725	COG0346	lactoylglutathione lyase activity
CPI37_RS03750	COG1119	ATPase activity
CPI37_RS03770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CPI37_RS03835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS03840	COG1120	ATPase activity
CPI37_RS03850	COG0205	6-phosphofructokinase activity
CPI37_RS03860	COG0667	Aldo Keto reductase
CPI37_RS03870	COG0583	DNA-binding transcription factor activity
CPI37_RS03895	COG0668	transmembrane transport
CPI37_RS03900	COG0028	Belongs to the TPP enzyme family
CPI37_RS03935	COG0473	3-isopropylmalate dehydrogenase activity
CPI37_RS03955	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPI37_RS03985	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CPI37_RS04020	COG0406	alpha-ribazole phosphatase activity
CPI37_RS04020	COG0494	nUDIX hydrolase
CPI37_RS04040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CPI37_RS04045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CPI37_RS04050	COG1461	Dihydroxyacetone kinase
CPI37_RS04060	COG0511	ligase activity, forming carbon-carbon bonds
CPI37_RS04065	COG0742	ribosomal rna small subunit methyltransferase
CPI37_RS04090	COG0765	amino acid transport
CPI37_RS04115	COG2226	methyltransferase
CPI37_RS04120	COG0539	negative regulation of cytoplasmic translation
CPI37_RS04130	COG0237	dephospho-CoA kinase activity
CPI37_RS04150	COG3973	AAA domain
CPI37_RS04175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPI37_RS04190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPI37_RS04205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CPI37_RS04220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CPI37_RS04240	COG0165	Argininosuccinate lyase
CPI37_RS04245	COG2835	tetraacyldisaccharide 4'-kinase activity
CPI37_RS04280	COG0647	UMP catabolic process
CPI37_RS04310	COG0494	nUDIX hydrolase
CPI37_RS04315	COG4974	Belongs to the 'phage' integrase family
CPI37_RS04335	COG3104	oligopeptide transport
CPI37_RS04340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CPI37_RS04350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CPI37_RS04365	COG1160	GTP binding
CPI37_RS04370	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPI37_RS04380	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CPI37_RS04385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CPI37_RS04390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CPI37_RS04395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS04400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS04405	COG1120	ATPase activity
CPI37_RS04410	COG4264	IucA IucC family
CPI37_RS04425	COG3012	SEC-C Motif Domain Protein
CPI37_RS04435	COG0653	protein targeting
CPI37_RS04475	COG1253	flavin adenine dinucleotide binding
CPI37_RS04480	COG0513	Belongs to the DEAD box helicase family
CPI37_RS04485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CPI37_RS04495	COG0598	Magnesium transport protein CorA
CPI37_RS04515	COG0477	Major facilitator Superfamily
CPI37_RS04540	COG0463	Glycosyl transferase, family 2
CPI37_RS04590	COG0300	oxidoreductase activity
CPI37_RS04605	COG0805	protein transport
CPI37_RS04615	COG2378	regulation of single-species biofilm formation
CPI37_RS04635	COG4122	O-methyltransferase activity
CPI37_RS04650	COG1362	aminopeptidase activity
CPI37_RS04670	COG1027	Aspartate ammonia-lyase
CPI37_RS04675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPI37_RS04695	COG0646	methionine synthase
CPI37_RS04695	COG1410	methionine synthase
CPI37_RS04715	COG0667	Aldo Keto reductase
CPI37_RS04725	COG0167	dihydroorotate dehydrogenase activity
CPI37_RS04750	COG1461	Dihydroxyacetone kinase
CPI37_RS04755	COG2376	Dihydroxyacetone kinase
CPI37_RS04765	COG0488	(ABC) transporter
CPI37_RS04830	COG0791	NLP P60 protein
CPI37_RS04830	COG3883	PFAM NLP P60 protein
CPI37_RS04860	COG2848	UPF0210 protein
CPI37_RS04885	COG2151	metal-sulfur cluster biosynthetic enzyme
CPI37_RS04890	COG0822	iron-sulfur transferase activity
CPI37_RS04900	COG0396	ATPase activity
CPI37_RS04945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPI37_RS04950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPI37_RS04970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPI37_RS04990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPI37_RS05000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CPI37_RS05010	COG0322	excinuclease ABC activity
CPI37_RS05040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPI37_RS05055	COG0242	peptide deformylase activity
CPI37_RS05095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPI37_RS05105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CPI37_RS05120	COG1090	epimerase
CPI37_RS05145	COG0006	proline dipeptidase activity
CPI37_RS05150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CPI37_RS05155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CPI37_RS05160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPI37_RS05165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CPI37_RS05180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CPI37_RS05185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPI37_RS05240	COG1760	l-serine dehydratase
CPI37_RS05265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPI37_RS05270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPI37_RS05285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPI37_RS05300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPI37_RS05305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPI37_RS05350	COG0156	8-amino-7-oxononanoate synthase activity
CPI37_RS05365	COG1560	Kdo2-lipid A biosynthetic process
CPI37_RS05370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CPI37_RS05385	COG2837	iron assimilation
CPI37_RS05440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPI37_RS05445	COG3253	May function as heme-dependent peroxidase
CPI37_RS05530	COG2890	protein-(glutamine-N5) methyltransferase activity
CPI37_RS05570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CPI37_RS05575	COG0450	alkyl hydroperoxide reductase
CPI37_RS05590	COG1643	Atp-dependent helicase
CPI37_RS05610	COG1349	DNA-binding transcription factor activity
CPI37_RS05615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPI37_RS05620	COG1349	DNA-binding transcription factor activity
CPI37_RS05625	COG1105	Belongs to the carbohydrate kinase PfkB family
CPI37_RS05630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPI37_RS05630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPI37_RS05630	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CPI37_RS05640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPI37_RS05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPI37_RS05655	COG2233	PERMEase
CPI37_RS05660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPI37_RS05675	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPI37_RS05690	COG1196	nuclear chromosome segregation
CPI37_RS05710	COG2137	regulation of response to DNA damage stimulus
CPI37_RS05715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPI37_RS05725	COG1268	BioY protein
CPI37_RS05730	COG1122	ATPase activity
CPI37_RS05740	COG1842	Phage shock protein A
CPI37_RS05745	COG1396	sequence-specific DNA binding
CPI37_RS05770	COG1674	ftsk spoiiie
CPI37_RS05780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPI37_RS05820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CPI37_RS05830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CPI37_RS05835	COG0534	Mate efflux family protein
CPI37_RS05880	COG3022	response to hydroperoxide
CPI37_RS05885	COG1648	precorrin-2 dehydrogenase activity
CPI37_RS05885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CPI37_RS05895	COG0523	cobalamin synthesis protein
CPI37_RS05900	COG2169	Transcriptional regulator
CPI37_RS05900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPI37_RS05965	COG0750	zinc metalloprotease
CPI37_RS06025	COG4974	Belongs to the 'phage' integrase family
CPI37_RS06050	COG0681	Belongs to the peptidase S26 family
CPI37_RS06065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPI37_RS06065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPI37_RS06065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPI37_RS06075	COG0336	Belongs to the RNA methyltransferase TrmD family
CPI37_RS06080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CPI37_RS06100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CPI37_RS06125	COG1254	Belongs to the acylphosphatase family
CPI37_RS06130	COG1115	amino acid carrier protein
CPI37_RS06135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPI37_RS06160	COG0686	Belongs to the AlaDH PNT family
CPI37_RS06165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CPI37_RS06175	COG1929	Belongs to the glycerate kinase type-1 family
CPI37_RS06195	COG0058	SHG alpha-glucan phosphorylase activity
CPI37_RS06205	COG0469	pyruvate kinase activity
CPI37_RS06215	COG0134	indole-3-glycerol-phosphate synthase activity
CPI37_RS06235	COG0483	inositol monophosphate 1-phosphatase activity
CPI37_RS06300	COG2176	DNA-directed DNA polymerase activity
CPI37_RS06325	COG1739	Uncharacterized protein family UPF0029
CPI37_RS06330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPI37_RS06355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPI37_RS06370	COG0252	asparaginase activity
CPI37_RS06390	COG3599	regulation of cell shape
CPI37_RS06400	COG1799	cell septum assembly
CPI37_RS06410	COG1496	oxidoreductase activity
CPI37_RS06415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPI37_RS06425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPI37_RS06455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPI37_RS06460	COG0768	penicillin binding
CPI37_RS06505	COG0142	geranyltranstransferase activity
CPI37_RS06525	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CPI37_RS06545	COG1940	carbohydrate kinase activity
CPI37_RS06550	COG0438	transferase activity, transferring glycosyl groups
CPI37_RS06560	COG0791	NLP P60 protein
CPI37_RS06610	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CPI37_RS06615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CPI37_RS06625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPI37_RS06640	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPI37_RS06645	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPI37_RS06645	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPI37_RS06650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CPI37_RS06655	COG0509	glycine decarboxylation via glycine cleavage system
CPI37_RS06685	COG0174	glutamine synthetase
CPI37_RS06730	COG2056	Na+-H+ antiporter family
CPI37_RS06755	COG1494	fructose-1,6-bisphosphatase
CPI37_RS06760	COG0114	fumarate hydratase activity
CPI37_RS06830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CPI37_RS06895	COG3956	TIGRFAM MazG family protein
CPI37_RS06900	COG0531	amino acid
CPI37_RS06910	COG1309	transcriptional regulator
CPI37_RS06925	COG2132	Multicopper oxidase
CPI37_RS06930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CPI37_RS06935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPI37_RS06940	COG1523	belongs to the glycosyl hydrolase 13 family
CPI37_RS06960	COG2070	2-Nitropropane dioxygenase
CPI37_RS06965	COG0193	aminoacyl-tRNA hydrolase activity
CPI37_RS06975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CPI37_RS06980	COG0596	Alpha beta hydrolase
CPI37_RS07010	COG0561	phosphatase activity
CPI37_RS07020	COG2326	polyphosphate kinase activity
CPI37_RS07035	COG0488	(ABC) transporter
CPI37_RS07050	COG3583	domain protein
CPI37_RS07055	COG0084	hydrolase, TatD family'
CPI37_RS07070	COG3949	Membrane
CPI37_RS07075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPI37_RS07085	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CPI37_RS07095	COG2259	Doxx family
CPI37_RS07115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPI37_RS07140	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPI37_RS07140	COG0315	cyclic pyranopterin monophosphate synthase activity
CPI37_RS07145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPI37_RS07150	COG2205	protein histidine kinase activity
CPI37_RS07155	COG0745	RESPONSE REGULATOR receiver
CPI37_RS07165	COG0254	rRNA binding
CPI37_RS07195	COG1309	transcriptional regulator
CPI37_RS07205	COG0765	amino acid transport
CPI37_RS07210	COG0765	amino acid transport
CPI37_RS07215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPI37_RS07220	COG1126	abc transporter atp-binding protein
CPI37_RS07270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPI37_RS07305	COG1201	RNA secondary structure unwinding
CPI37_RS07315	COG1218	3'(2'),5'-bisphosphate nucleotidase
CPI37_RS07330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPI37_RS07355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPI37_RS07365	COG0601	transmembrane transport
CPI37_RS07370	COG4166	transmembrane transport
CPI37_RS07385	COG0019	diaminopimelate decarboxylase activity
CPI37_RS07390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPI37_RS07395	COG0534	Mate efflux family protein
CPI37_RS07415	COG3757	hydrolase, family 25
CPI37_RS07425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPI37_RS07435	COG1024	Enoyl-CoA hydratase
CPI37_RS07440	COG0656	L-ascorbic acid biosynthetic process
CPI37_RS07455	COG0545	Peptidyl-prolyl cis-trans isomerase
CPI37_RS07460	COG0372	Belongs to the citrate synthase family
CPI37_RS07480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPI37_RS07485	COG2252	PERMEase
CPI37_RS07510	COG1652	LysM domain
CPI37_RS07525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CPI37_RS07550	COG0174	glutamine synthetase
CPI37_RS07575	COG0557	exoribonuclease II activity
CPI37_RS07595	COG3323	Protein of unknown function (DUF1653)
CPI37_RS07595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPI37_RS07635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CPI37_RS07640	COG0596	Alpha beta hydrolase
CPI37_RS07665	COG2860	membrane
CPI37_RS07735	COG0423	glycine-tRNA ligase activity
CPI37_RS07765	COG1381	Involved in DNA repair and RecF pathway recombination
CPI37_RS07820	COG1022	Amp-dependent synthetase and ligase
CPI37_RS07865	COG1132	(ABC) transporter
CPI37_RS07870	COG1114	Component of the transport system for branched-chain amino acids
CPI37_RS07875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPI37_RS07885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPI37_RS07900	COG0747	negative chemotaxis
CPI37_RS07905	COG0601	transmembrane transport
CPI37_RS07910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPI37_RS07915	COG4172	Belongs to the ABC transporter superfamily
CPI37_RS07925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPI37_RS07930	COG2391	methyltransferase activity
CPI37_RS07940	COG4171	peptide transport system, permease
CPI37_RS07955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPI37_RS07960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPI37_RS07980	COG1280	lysine exporter protein (LysE YggA)
CPI37_RS08000	COG1555	photosystem II stabilization
CPI37_RS08000	COG1596	polysaccharide export
CPI37_RS08005	COG1307	EDD domain protein, DegV family
CPI37_RS08010	COG0406	alpha-ribazole phosphatase activity
CPI37_RS08020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CPI37_RS08035	COG2832	Protein of unknown function (DUF454)
CPI37_RS08040	COG0569	domain protein
CPI37_RS08040	COG2985	domain, Protein
CPI37_RS08080	COG2423	ornithine cyclodeaminase activity
CPI37_RS08090	COG0285	dihydrofolate synthase activity
CPI37_RS08130	COG0544	peptidyl-prolyl cis-trans isomerase activity
CPI37_RS08165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CPI37_RS08175	COG0668	transmembrane transport
CPI37_RS08255	COG1131	(ABC) transporter
CPI37_RS08260	COG3336	cytochrome c oxidase
CPI37_RS08265	COG1966	Carbon starvation protein
CPI37_RS08285	COG0604	alcohol dehydrogenase
CPI37_RS08310	COG1376	ErfK ybiS ycfS ynhG family protein
CPI37_RS08340	COG2130	NADP-dependent
CPI37_RS08345	COG1335	isochorismatase
CPI37_RS08390	COG2197	response regulator
CPI37_RS08435	COG1234	tRNA 3'-trailer cleavage
CPI37_RS08460	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CPI37_RS08595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPI37_RS08605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPI37_RS08625	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPI37_RS08645	COG2217	Heavy metal translocating P-type atpase
CPI37_RS08690	COG0033	Phosphoglucomutase
CPI37_RS08705	COG1136	(ABC) transporter
CPI37_RS08705	COG0577	efflux transmembrane transporter activity
CPI37_RS08710	COG1136	(ABC) transporter
CPI37_RS08710	COG0577	efflux transmembrane transporter activity
CPI37_RS08745	COG2197	response regulator
CPI37_RS08760	COG1045	serine acetyltransferase
CPI37_RS08780	COG0371	Dehydrogenase
CPI37_RS08800	COG1271	oxidase subunit
CPI37_RS08805	COG1294	oxidase, subunit
CPI37_RS08810	COG4988	ABC transporter
CPI37_RS08815	COG1132	(ABC) transporter
CPI37_RS08840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CPI37_RS08870	COG1597	lipid kinase activity
CPI37_RS08885	COG0354	folic acid binding
CPI37_RS08910	COG1780	Probably involved in ribonucleotide reductase function
CPI37_RS08915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPI37_RS08925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPI37_RS08930	COG0047	phosphoribosylformylglycinamidine synthase activity
CPI37_RS08935	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPI37_RS08940	COG0386	Belongs to the glutathione peroxidase family
CPI37_RS08960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPI37_RS08965	COG0569	domain protein
CPI37_RS08970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPI37_RS08975	COG0151	Belongs to the GarS family
CPI37_RS08980	COG0537	adenosine 5'-monophosphoramidase activity
CPI37_RS08990	COG2205	protein histidine kinase activity
CPI37_RS08995	COG0745	RESPONSE REGULATOR receiver
CPI37_RS09025	COG0028	Belongs to the TPP enzyme family
CPI37_RS09075	COG1609	Transcriptional regulator
CPI37_RS09085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPI37_RS09105	COG1329	Transcriptional regulator
CPI37_RS09110	COG2847	Copper chaperone PCu(A)C
CPI37_RS09125	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPI37_RS09135	COG0288	reversible hydration of carbon dioxide
CPI37_RS09165	COG0477	Major facilitator Superfamily
CPI37_RS09170	COG1957	nucleoside hydrolase
CPI37_RS09190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPI37_RS09205	COG1301	dicarboxylic acid transport
CPI37_RS09210	COG1012	belongs to the aldehyde dehydrogenase family
CPI37_RS09215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPI37_RS09220	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CPI37_RS09225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CPI37_RS09255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPI37_RS09260	COG0302	gtp cyclohydrolase
CPI37_RS09265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPI37_RS09270	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CPI37_RS09280	COG2027	D-alanyl-D-alanine carboxypeptidase
CPI37_RS09285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CPI37_RS09290	COG0425	Belongs to the sulfur carrier protein TusA family
CPI37_RS09290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPI37_RS09295	COG1301	dicarboxylic acid transport
CPI37_RS09320	COG2326	polyphosphate kinase activity
CPI37_RS09365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPI37_RS09365	COG2111	Na H antiporter
CPI37_RS09370	COG1006	Multisubunit Na H antiporter MnhC subunit
CPI37_RS09375	COG0651	ATP synthesis coupled electron transport
CPI37_RS09395	COG1051	belongs to the nudix hydrolase family
CPI37_RS09415	COG0242	peptide deformylase activity
CPI37_RS09420	COG0456	acetyltransferase
CPI37_RS09430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPI37_RS09455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPI37_RS09470	COG0280	phosphate acetyltransferase
CPI37_RS09490	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CPI37_RS09525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPI37_RS09530	COG1333	cytochrome c biogenesis protein
CPI37_RS09540	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CPI37_RS09545	COG3005	denitrification pathway
CPI37_RS09560	COG4129	membrane
CPI37_RS09570	COG4129	membrane
CPI37_RS09605	COG0191	fructose-bisphosphate aldolase activity
CPI37_RS09620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPI37_RS09635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CPI37_RS09675	COG1131	(ABC) transporter
CPI37_RS09710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CPI37_RS09720	COG0577	efflux transmembrane transporter activity
CPI37_RS09720	COG1136	(ABC) transporter
CPI37_RS09725	COG1136	(ABC) transporter
CPI37_RS09730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPI37_RS09755	COG1012	belongs to the aldehyde dehydrogenase family
CPI37_RS09770	COG0789	Transcriptional regulator
CPI37_RS09785	COG0443	Heat shock 70 kDa protein
CPI37_RS09815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPI37_RS09820	COG0601	transmembrane transport
CPI37_RS09840	COG0247	lactate metabolic process
CPI37_RS09840	COG2181	nitrate reductase activity
CPI37_RS09855	COG1120	ATPase activity
CPI37_RS09860	COG4139	cobalamin transport
CPI37_RS09870	COG0829	nickel cation binding
CPI37_RS09875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CPI37_RS09880	COG0830	nickel cation binding
CPI37_RS09885	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CPI37_RS09890	COG0804	urea catabolic process
CPI37_RS09895	COG0832	Belongs to the urease beta subunit family
CPI37_RS09900	COG0831	urea catabolic process
CPI37_RS09925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPI37_RS09925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CPI37_RS09945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CPI37_RS09960	COG1012	belongs to the aldehyde dehydrogenase family
CPI37_RS09970	COG1472	Belongs to the glycosyl hydrolase 3 family
CPI37_RS09980	COG4981	capsule polysaccharide biosynthetic process
CPI37_RS09985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CPI37_RS09985	COG2755	lipolytic protein G-D-S-L family
CPI37_RS10000	COG0438	transferase activity, transferring glycosyl groups
CPI37_RS10005	COG0500	methyltransferase
CPI37_RS10050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPI37_RS10055	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CPI37_RS10055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPI37_RS10055	COG3321	synthase
CPI37_RS10060	COG0318	PFAM AMP-dependent synthetase and ligase
CPI37_RS10065	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CPI37_RS10075	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CPI37_RS10075	COG5479	isomerase activity
CPI37_RS10090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CPI37_RS10100	COG1216	Glycosyl transferase, family 2
CPI37_RS10110	COG0671	phosphoesterase, PA-phosphatase related
CPI37_RS10120	COG0584	glycerophosphoryl diester phosphodiesterase
CPI37_RS10125	COG2271	Major facilitator Superfamily
CPI37_RS10135	COG1120	ATPase activity
CPI37_RS10140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPI37_RS10145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPI37_RS10155	COG0561	phosphatase activity
CPI37_RS10170	COG2188	Transcriptional regulator
CPI37_RS10195	COG0154	amidase activity
CPI37_RS10205	COG1316	TRANSCRIPTIONal
CPI37_RS10220	COG1115	amino acid carrier protein
CPI37_RS10240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPI37_RS10265	COG3547	Transposase (IS116 IS110 IS902 family)
CPI37_RS10275	COG0431	NADPH-dependent FMN reductase
CPI37_RS10280	COG2814	Major facilitator Superfamily
CPI37_RS10305	COG5650	phosphatidylinositol metabolic process
CPI37_RS10325	COG2197	response regulator
CPI37_RS10340	COG3764	Sortase (surface protein transpeptidase)
CPI37_RS10345	COG0706	membrane insertase activity
CPI37_RS10370	COG0564	pseudouridine synthase activity
CPI37_RS10400	COG1131	(ABC) transporter
CPI37_RS10415	COG1842	Phage shock protein A
CPI37_RS10420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPI37_RS10435	COG0477	Major facilitator Superfamily
CPI37_RS10440	COG0305	Participates in initiation and elongation during chromosome replication
CPI37_RS10485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPI37_RS10525	COG0783	Belongs to the Dps family
CPI37_RS10530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPI37_RS10535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPI37_RS10535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPI37_RS10545	COG1511	domain protein
CPI37_RS10555	COG1136	(ABC) transporter
CPI37_RS10555	COG0577	efflux transmembrane transporter activity
CPI37_RS10570	COG4585	Histidine kinase
CPI37_RS10575	COG2197	response regulator
CPI37_RS10590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPI37_RS10605	COG2186	Transcriptional regulator
CPI37_RS10610	COG0747	negative chemotaxis
CPI37_RS10615	COG0601	transmembrane transport
CPI37_RS10620	COG0444	Belongs to the ABC transporter superfamily
CPI37_RS10625	COG4608	Belongs to the ABC transporter superfamily
CPI37_RS10630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPI37_RS10670	COG3422	double-strand break repair
CPI37_RS10685	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CPI37_RS10705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPI37_RS10710	COG0512	Glutamine amidotransferase of anthranilate synthase
CPI37_RS10720	COG0135	phosphoribosylanthranilate isomerase activity
CPI37_RS10720	COG0134	indole-3-glycerol-phosphate synthase activity
CPI37_RS10755	COG1687	branched-chain amino acid
CPI37_RS10760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CPI37_RS10765	COG1678	Uncharacterized ACR, COG1678
CPI37_RS10770	COG0617	tRNA 3'-terminal CCA addition
CPI37_RS10805	COG3409	Peptidoglycan-binding domain 1 protein
CPI37_RS10805	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPI37_RS10820	COG1192	Involved in chromosome partitioning
CPI37_RS10835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CPI37_RS10845	COG0230	Belongs to the bacterial ribosomal protein bL34 family