locus-tag	class	description
ATN04_RS00025	COG1061	Type III restriction enzyme res subunit
ATN04_RS00040	COG1652	LysM domain
ATN04_RS00065	COG2252	PERMEase
ATN04_RS00070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATN04_RS00090	COG0372	Belongs to the citrate synthase family
ATN04_RS00095	COG0545	Peptidyl-prolyl cis-trans isomerase
ATN04_RS00110	COG0656	L-ascorbic acid biosynthetic process
ATN04_RS00115	COG1024	Enoyl-CoA hydratase
ATN04_RS00125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATN04_RS00135	COG3757	hydrolase, family 25
ATN04_RS00150	COG0534	Mate efflux family protein
ATN04_RS00155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ATN04_RS00160	COG0019	diaminopimelate decarboxylase activity
ATN04_RS00175	COG4166	transmembrane transport
ATN04_RS00180	COG0601	transmembrane transport
ATN04_RS00190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ATN04_RS00210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ATN04_RS00225	COG1218	3'(2'),5'-bisphosphate nucleotidase
ATN04_RS00230	COG1201	RNA secondary structure unwinding
ATN04_RS00240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATN04_RS00295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATN04_RS00300	COG0765	amino acid transport
ATN04_RS00305	COG0765	amino acid transport
ATN04_RS00315	COG1309	transcriptional regulator
ATN04_RS00345	COG0254	rRNA binding
ATN04_RS00355	COG0745	RESPONSE REGULATOR receiver
ATN04_RS00360	COG2205	protein histidine kinase activity
ATN04_RS00365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATN04_RS00370	COG0315	cyclic pyranopterin monophosphate synthase activity
ATN04_RS00370	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATN04_RS00390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ATN04_RS00410	COG2259	Doxx family
ATN04_RS00430	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
ATN04_RS00435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ATN04_RS00440	COG3949	Membrane
ATN04_RS00455	COG0084	hydrolase, TatD family'
ATN04_RS00460	COG3583	domain protein
ATN04_RS00475	COG0488	(ABC) transporter
ATN04_RS00490	COG2326	polyphosphate kinase activity
ATN04_RS00500	COG0561	phosphatase activity
ATN04_RS00525	COG0596	Alpha beta hydrolase
ATN04_RS00530	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ATN04_RS00540	COG0193	aminoacyl-tRNA hydrolase activity
ATN04_RS00545	COG2070	2-Nitropropane dioxygenase
ATN04_RS00565	COG1523	belongs to the glycosyl hydrolase 13 family
ATN04_RS00570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATN04_RS00575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATN04_RS00595	COG1309	transcriptional regulator
ATN04_RS00610	COG3956	TIGRFAM MazG family protein
ATN04_RS00675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ATN04_RS00745	COG0114	fumarate hydratase activity
ATN04_RS00750	COG1494	fructose-1,6-bisphosphatase
ATN04_RS00775	COG2801	Transposase and inactivated derivatives
ATN04_RS00795	COG0012	GTP binding
ATN04_RS00805	COG2824	Alkylphosphonate utilization operon protein PhnA
ATN04_RS00810	COG1132	(ABC) transporter
ATN04_RS00815	COG1132	(ABC) transporter
ATN04_RS00820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATN04_RS00825	COG2354	Protein conserved in bacteria
ATN04_RS00835	COG4721	ABC-type cobalt transport system, permease component
ATN04_RS00840	COG1122	ATPase activity
ATN04_RS00860	COG4166	transmembrane transport
ATN04_RS00865	COG0601	transmembrane transport
ATN04_RS00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATN04_RS00900	COG1217	gtp-binding protein TYPA
ATN04_RS00905	COG4166	transmembrane transport
ATN04_RS00940	COG1113	amino acid transport
ATN04_RS00950	COG1113	amino acid transport
ATN04_RS00960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATN04_RS00965	COG1611	Belongs to the LOG family
ATN04_RS00970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATN04_RS00975	COG0463	Glycosyl transferase, family 2
ATN04_RS00995	COG3527	Alpha-acetolactate decarboxylase
ATN04_RS01000	COG0297	glycogen (starch) synthase activity
ATN04_RS01010	COG4122	O-methyltransferase activity
ATN04_RS01040	COG2239	Acts as a magnesium transporter
ATN04_RS01055	COG1132	(ABC) transporter
ATN04_RS01070	COG2272	Belongs to the type-B carboxylesterase lipase family
ATN04_RS01085	COG2017	converts alpha-aldose to the beta-anomer
ATN04_RS01105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ATN04_RS01135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATN04_RS01140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATN04_RS01165	COG1846	Transcriptional regulator
ATN04_RS01195	COG1556	Lactate utilization protein
ATN04_RS01200	COG1139	Iron-sulfur cluster binding protein
ATN04_RS01205	COG0247	lactate metabolic process
ATN04_RS01220	COG0019	diaminopimelate decarboxylase activity
ATN04_RS01225	COG0460	homoserine dehydrogenase
ATN04_RS01275	COG0356	it plays a direct role in the translocation of protons across the membrane
ATN04_RS01280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATN04_RS01285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATN04_RS01325	COG0346	lactoylglutathione lyase activity
ATN04_RS01350	COG1119	ATPase activity
ATN04_RS01370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ATN04_RS01435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS01440	COG1120	ATPase activity
ATN04_RS01450	COG0205	6-phosphofructokinase activity
ATN04_RS01460	COG0667	Aldo Keto reductase
ATN04_RS01470	COG0583	DNA-binding transcription factor activity
ATN04_RS01495	COG0668	transmembrane transport
ATN04_RS01500	COG0028	Belongs to the TPP enzyme family
ATN04_RS01535	COG0473	3-isopropylmalate dehydrogenase activity
ATN04_RS01555	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATN04_RS01585	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ATN04_RS01620	COG0406	alpha-ribazole phosphatase activity
ATN04_RS01620	COG0494	nUDIX hydrolase
ATN04_RS01640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ATN04_RS01645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ATN04_RS01650	COG1461	Dihydroxyacetone kinase
ATN04_RS01660	COG0511	ligase activity, forming carbon-carbon bonds
ATN04_RS01665	COG0742	ribosomal rna small subunit methyltransferase
ATN04_RS01690	COG0765	amino acid transport
ATN04_RS01735	COG2226	methyltransferase
ATN04_RS01740	COG0539	negative regulation of cytoplasmic translation
ATN04_RS01750	COG0237	dephospho-CoA kinase activity
ATN04_RS01770	COG3973	AAA domain
ATN04_RS01795	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ATN04_RS01810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATN04_RS01825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ATN04_RS01840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATN04_RS01860	COG0165	Argininosuccinate lyase
ATN04_RS01865	COG2835	tetraacyldisaccharide 4'-kinase activity
ATN04_RS01900	COG0647	UMP catabolic process
ATN04_RS01930	COG0494	nUDIX hydrolase
ATN04_RS01935	COG4974	Belongs to the 'phage' integrase family
ATN04_RS01955	COG3104	oligopeptide transport
ATN04_RS01960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATN04_RS01970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATN04_RS01985	COG1160	GTP binding
ATN04_RS01990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ATN04_RS02000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATN04_RS02005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ATN04_RS02010	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ATN04_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS02025	COG1120	ATPase activity
ATN04_RS02030	COG4264	IucA IucC family
ATN04_RS02050	COG0653	protein targeting
ATN04_RS02090	COG1253	flavin adenine dinucleotide binding
ATN04_RS02095	COG0513	Belongs to the DEAD box helicase family
ATN04_RS02100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ATN04_RS02110	COG0598	Magnesium transport protein CorA
ATN04_RS02130	COG0477	Major facilitator Superfamily
ATN04_RS02155	COG0463	Glycosyl transferase, family 2
ATN04_RS02205	COG0300	oxidoreductase activity
ATN04_RS02220	COG0805	protein transport
ATN04_RS02230	COG2378	regulation of single-species biofilm formation
ATN04_RS02250	COG4122	O-methyltransferase activity
ATN04_RS02265	COG1362	aminopeptidase activity
ATN04_RS02285	COG1027	Aspartate ammonia-lyase
ATN04_RS02290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ATN04_RS02310	COG0646	methionine synthase
ATN04_RS02310	COG1410	methionine synthase
ATN04_RS02330	COG0667	Aldo Keto reductase
ATN04_RS02340	COG0167	dihydroorotate dehydrogenase activity
ATN04_RS02365	COG1461	Dihydroxyacetone kinase
ATN04_RS02370	COG2376	Dihydroxyacetone kinase
ATN04_RS02380	COG0488	(ABC) transporter
ATN04_RS02445	COG3883	PFAM NLP P60 protein
ATN04_RS02445	COG0791	NLP P60 protein
ATN04_RS02475	COG2848	UPF0210 protein
ATN04_RS02490	COG4932	domain protein
ATN04_RS02490	COG1388	LysM domain
ATN04_RS02495	COG0488	(ABC) transporter
ATN04_RS02500	COG2151	metal-sulfur cluster biosynthetic enzyme
ATN04_RS02505	COG0822	iron-sulfur transferase activity
ATN04_RS02515	COG0396	ATPase activity
ATN04_RS02560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ATN04_RS02565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATN04_RS02585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATN04_RS02605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ATN04_RS02625	COG0322	excinuclease ABC activity
ATN04_RS02655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATN04_RS02670	COG0242	peptide deformylase activity
ATN04_RS02710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATN04_RS02720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATN04_RS02735	COG1090	epimerase
ATN04_RS02760	COG0006	proline dipeptidase activity
ATN04_RS02765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATN04_RS02770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATN04_RS02775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATN04_RS02780	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATN04_RS02790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATN04_RS02800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATN04_RS02855	COG1760	l-serine dehydratase
ATN04_RS02885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATN04_RS02890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ATN04_RS02905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATN04_RS02920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATN04_RS02925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATN04_RS02955	COG1946	Acyl-CoA thioesterase
ATN04_RS02970	COG0156	8-amino-7-oxononanoate synthase activity
ATN04_RS02985	COG1560	Kdo2-lipid A biosynthetic process
ATN04_RS02990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATN04_RS03005	COG2837	iron assimilation
ATN04_RS03070	COG3253	May function as heme-dependent peroxidase
ATN04_RS03155	COG2890	protein-(glutamine-N5) methyltransferase activity
ATN04_RS03195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATN04_RS03200	COG0450	alkyl hydroperoxide reductase
ATN04_RS03215	COG1643	Atp-dependent helicase
ATN04_RS03235	COG1349	DNA-binding transcription factor activity
ATN04_RS03240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATN04_RS03245	COG1349	DNA-binding transcription factor activity
ATN04_RS03250	COG1105	Belongs to the carbohydrate kinase PfkB family
ATN04_RS03255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATN04_RS03255	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ATN04_RS03255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATN04_RS03260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATN04_RS03275	COG2233	PERMEase
ATN04_RS03280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATN04_RS03295	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ATN04_RS03310	COG1196	nuclear chromosome segregation
ATN04_RS03330	COG2137	regulation of response to DNA damage stimulus
ATN04_RS03335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATN04_RS03345	COG1268	BioY protein
ATN04_RS03350	COG1122	ATPase activity
ATN04_RS03360	COG1842	Phage shock protein A
ATN04_RS03365	COG1396	sequence-specific DNA binding
ATN04_RS03390	COG1674	ftsk spoiiie
ATN04_RS03400	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ATN04_RS03440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ATN04_RS03450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ATN04_RS03455	COG0534	Mate efflux family protein
ATN04_RS03500	COG3022	response to hydroperoxide
ATN04_RS03505	COG1648	precorrin-2 dehydrogenase activity
ATN04_RS03505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATN04_RS03510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ATN04_RS03515	COG0523	cobalamin synthesis protein
ATN04_RS03520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATN04_RS03520	COG2169	Transcriptional regulator
ATN04_RS03585	COG0750	zinc metalloprotease
ATN04_RS03645	COG4974	Belongs to the 'phage' integrase family
ATN04_RS03675	COG0681	Belongs to the peptidase S26 family
ATN04_RS03690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATN04_RS03690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATN04_RS03690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATN04_RS03700	COG0336	Belongs to the RNA methyltransferase TrmD family
ATN04_RS03705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATN04_RS03755	COG1115	amino acid carrier protein
ATN04_RS03760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATN04_RS03785	COG0686	Belongs to the AlaDH PNT family
ATN04_RS03790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATN04_RS03800	COG1929	Belongs to the glycerate kinase type-1 family
ATN04_RS03820	COG0058	SHG alpha-glucan phosphorylase activity
ATN04_RS03830	COG0469	pyruvate kinase activity
ATN04_RS03840	COG0134	indole-3-glycerol-phosphate synthase activity
ATN04_RS03860	COG0483	inositol monophosphate 1-phosphatase activity
ATN04_RS03950	COG1739	Uncharacterized protein family UPF0029
ATN04_RS03955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATN04_RS03980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ATN04_RS03995	COG0252	asparaginase activity
ATN04_RS04015	COG3599	regulation of cell shape
ATN04_RS04025	COG1799	cell septum assembly
ATN04_RS04030	COG1496	oxidoreductase activity
ATN04_RS04035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATN04_RS04045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATN04_RS04075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATN04_RS04080	COG0768	penicillin binding
ATN04_RS04120	COG0142	geranyltranstransferase activity
ATN04_RS04135	COG0515	serine threonine protein kinase
ATN04_RS04135	COG2815	serine threonine protein kinase
ATN04_RS04140	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ATN04_RS04160	COG1940	carbohydrate kinase activity
ATN04_RS04165	COG0438	transferase activity, transferring glycosyl groups
ATN04_RS04175	COG0791	NLP P60 protein
ATN04_RS04225	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ATN04_RS04230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ATN04_RS04240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATN04_RS04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATN04_RS04260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATN04_RS04260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATN04_RS04265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ATN04_RS04270	COG0509	glycine decarboxylation via glycine cleavage system
ATN04_RS04300	COG0174	glutamine synthetase
ATN04_RS04335	COG3547	Transposase (IS116 IS110 IS902 family)
ATN04_RS04365	COG2056	Na+-H+ antiporter family
ATN04_RS04375	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATN04_RS04400	COG0174	glutamine synthetase
ATN04_RS04420	COG0557	exoribonuclease II activity
ATN04_RS04440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ATN04_RS04440	COG3323	Protein of unknown function (DUF1653)
ATN04_RS04480	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ATN04_RS04485	COG0596	Alpha beta hydrolase
ATN04_RS04510	COG2860	membrane
ATN04_RS04580	COG0423	glycine-tRNA ligase activity
ATN04_RS04605	COG1381	Involved in DNA repair and RecF pathway recombination
ATN04_RS04660	COG1022	Amp-dependent synthetase and ligase
ATN04_RS04710	COG1132	(ABC) transporter
ATN04_RS04715	COG1114	Component of the transport system for branched-chain amino acids
ATN04_RS04730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ATN04_RS04745	COG0747	negative chemotaxis
ATN04_RS04750	COG0601	transmembrane transport
ATN04_RS04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATN04_RS04760	COG4172	Belongs to the ABC transporter superfamily
ATN04_RS04770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATN04_RS04775	COG2391	methyltransferase activity
ATN04_RS04785	COG0601	transmembrane transport
ATN04_RS04800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ATN04_RS04805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ATN04_RS04825	COG1280	lysine exporter protein (LysE YggA)
ATN04_RS04845	COG1555	photosystem II stabilization
ATN04_RS04845	COG1596	polysaccharide export
ATN04_RS04850	COG1307	EDD domain protein, DegV family
ATN04_RS04855	COG0406	alpha-ribazole phosphatase activity
ATN04_RS04865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATN04_RS04880	COG2832	Protein of unknown function (DUF454)
ATN04_RS04885	COG2985	domain, Protein
ATN04_RS04885	COG0569	domain protein
ATN04_RS04910	COG1530	ribonuclease E activity
ATN04_RS04925	COG2423	ornithine cyclodeaminase activity
ATN04_RS04935	COG0285	dihydrofolate synthase activity
ATN04_RS04975	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATN04_RS05010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ATN04_RS05020	COG0668	transmembrane transport
ATN04_RS05095	COG1131	(ABC) transporter
ATN04_RS05100	COG3336	cytochrome c oxidase
ATN04_RS05105	COG1966	Carbon starvation protein
ATN04_RS05125	COG0604	alcohol dehydrogenase
ATN04_RS05150	COG1376	ErfK ybiS ycfS ynhG family protein
ATN04_RS05195	COG2130	NADP-dependent
ATN04_RS05200	COG1335	isochorismatase
ATN04_RS05245	COG2197	response regulator
ATN04_RS05290	COG1234	tRNA 3'-trailer cleavage
ATN04_RS05315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ATN04_RS05445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATN04_RS05455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATN04_RS05475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATN04_RS05495	COG2217	Heavy metal translocating P-type atpase
ATN04_RS05540	COG0577	efflux transmembrane transporter activity
ATN04_RS05540	COG1136	(ABC) transporter
ATN04_RS05545	COG1136	(ABC) transporter
ATN04_RS05545	COG0577	efflux transmembrane transporter activity
ATN04_RS05590	COG0288	reversible hydration of carbon dioxide
ATN04_RS05620	COG2177	Part of the ABC transporter FtsEX involved in
ATN04_RS05625	COG2884	Cell division ATP-binding protein ftsE
ATN04_RS05630	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ATN04_RS05645	COG0483	inositol monophosphate 1-phosphatase activity
ATN04_RS05650	COG0483	inositol monophosphate 1-phosphatase activity
ATN04_RS05755	COG3480	Lon protease (S16) C-terminal proteolytic domain
ATN04_RS05780	COG2816	NAD+ diphosphatase activity
ATN04_RS05815	COG0513	Belongs to the DEAD box helicase family
ATN04_RS05850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ATN04_RS05855	COG2135	peptidase activity
ATN04_RS05860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATN04_RS05900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ATN04_RS05915	COG5002	protein histidine kinase activity
ATN04_RS05920	COG0745	RESPONSE REGULATOR receiver
ATN04_RS05945	COG1482	cell wall glycoprotein biosynthetic process
ATN04_RS05975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ATN04_RS05985	COG1316	TRANSCRIPTIONal
ATN04_RS06035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ATN04_RS06035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ATN04_RS06040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATN04_RS06045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATN04_RS06055	COG1609	Transcriptional regulator
ATN04_RS06060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATN04_RS06065	COG0424	maF-like protein
ATN04_RS06075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ATN04_RS06075	COG2755	lipolytic protein G-D-S-L family
ATN04_RS06080	COG0189	ligase activity
ATN04_RS06085	COG2897	thiosulfate sulfurtransferase activity
ATN04_RS06090	COG4770	biotin carboxylase activity
ATN04_RS06115	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ATN04_RS06115	COG1473	amidohydrolase
ATN04_RS06120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATN04_RS06155	COG1686	Belongs to the peptidase S11 family
ATN04_RS06160	COG1295	ribonuclease BN
ATN04_RS06165	COG0180	Tryptophanyl-tRNA synthetase
ATN04_RS06185	COG2814	Major facilitator Superfamily
ATN04_RS06190	COG2838	Isocitrate dehydrogenase
ATN04_RS06195	COG2873	o-acetylhomoserine
ATN04_RS06210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS06245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATN04_RS06250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ATN04_RS06255	COG1321	iron dependent repressor
ATN04_RS06260	COG1321	iron dependent repressor
ATN04_RS06260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATN04_RS06270	COG1121	(ABC) transporter
ATN04_RS06275	COG0803	Belongs to the bacterial solute-binding protein 9 family
ATN04_RS06290	COG1464	Belongs to the NlpA lipoprotein family
ATN04_RS06295	COG1464	Belongs to the NlpA lipoprotein family
ATN04_RS06305	COG2011	ABC-type metal ion transport system permease component
ATN04_RS06350	COG0516	GMP reductase activity
ATN04_RS06415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATN04_RS06470	COG1674	ftsk spoiiie
ATN04_RS06480	COG1404	Belongs to the peptidase S8 family
ATN04_RS06500	COG0203	ribosomal protein L17
ATN04_RS06550	COG0201	protein transport
ATN04_RS06555	COG3842	ATPase activity
ATN04_RS06575	COG3833	ABC-type maltose transport systems, permease component
ATN04_RS06580	COG1175	transmembrane transport
ATN04_RS06625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ATN04_RS06635	COG0315	cyclic pyranopterin monophosphate synthase activity
ATN04_RS06640	COG0746	molybdenum cofactor guanylyltransferase activity
ATN04_RS06665	COG1140	nitrate reductase beta subunit
ATN04_RS06705	COG0252	asparaginase activity
ATN04_RS06710	COG1760	l-serine dehydratase
ATN04_RS06715	COG0814	amino acid
ATN04_RS06810	COG1302	Protein conserved in bacteria
ATN04_RS06880	COG0701	Predicted permease
ATN04_RS06895	COG1131	(ABC) transporter
ATN04_RS06900	COG2197	response regulator
ATN04_RS06930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATN04_RS06935	COG1121	(ABC) transporter
ATN04_RS06945	COG0803	Belongs to the bacterial solute-binding protein 9 family
ATN04_RS06965	COG1902	pentaerythritol trinitrate reductase activity
ATN04_RS06970	COG3579	cysteine-type endopeptidase activity
ATN04_RS06995	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATN04_RS07020	COG0142	geranyltranstransferase activity
ATN04_RS07025	COG0644	oxidoreductase
ATN04_RS07030	COG0039	L-malate dehydrogenase activity
ATN04_RS07040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ATN04_RS07040	COG0438	transferase activity, transferring glycosyl groups
ATN04_RS07055	COG4948	Mandelate Racemase Muconate Lactonizing
ATN04_RS07060	COG3069	C4-dicarboxylate transmembrane transporter activity
ATN04_RS07090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATN04_RS07095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS07110	COG0275	rRNA processing
ATN04_RS07120	COG0785	Cytochrome C biogenesis protein
ATN04_RS07130	COG0406	alpha-ribazole phosphatase activity
ATN04_RS07145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ATN04_RS07155	COG2217	Heavy metal translocating P-type atpase
ATN04_RS07170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATN04_RS07170	COG1648	precorrin-2 dehydrogenase activity
ATN04_RS07200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATN04_RS07200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATN04_RS07210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ATN04_RS07230	COG0745	RESPONSE REGULATOR receiver
ATN04_RS07235	COG5002	protein histidine kinase activity
ATN04_RS07250	COG0318	PFAM AMP-dependent synthetase and ligase
ATN04_RS07270	COG1882	Formate acetyltransferase
ATN04_RS07290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATN04_RS07300	COG2733	membrane
ATN04_RS07310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ATN04_RS07315	COG1053	succinate dehydrogenase
ATN04_RS07325	COG3800	Transcriptional regulator
ATN04_RS07325	COG1396	sequence-specific DNA binding
ATN04_RS07330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATN04_RS07340	COG1505	serine-type exopeptidase activity
ATN04_RS07350	COG1088	dTDP-glucose 4,6-dehydratase activity
ATN04_RS07360	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ATN04_RS07370	COG0318	PFAM AMP-dependent synthetase and ligase
ATN04_RS07385	COG0470	DNA polymerase III
ATN04_RS07395	COG1297	OPT oligopeptide transporter protein
ATN04_RS07400	COG1754	DNA topoisomerase type I activity
ATN04_RS07400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATN04_RS07475	COG0494	nUDIX hydrolase
ATN04_RS07495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATN04_RS07515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATN04_RS07545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATN04_RS07545	COG2111	Na H antiporter
ATN04_RS07555	COG0651	ATP synthesis coupled electron transport
ATN04_RS07585	COG2271	Major facilitator Superfamily
ATN04_RS07590	COG1840	ABC-type Fe3 transport system, periplasmic component
ATN04_RS07645	COG0527	aspartate kinase activity
ATN04_RS07650	COG0697	spore germination
ATN04_RS07685	COG0813	purine-nucleoside phosphorylase activity
ATN04_RS07690	COG2390	Transcriptional regulator
ATN04_RS07695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATN04_RS07700	COG0778	Nitroreductase
ATN04_RS07710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ATN04_RS07715	COG3442	glutamine amidotransferase
ATN04_RS07720	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATN04_RS07725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATN04_RS07735	COG2084	Dehydrogenase
ATN04_RS07740	COG2610	gluconate transmembrane transporter activity
ATN04_RS07765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATN04_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
ATN04_RS07785	COG1063	alcohol dehydrogenase
ATN04_RS07790	COG3265	gluconokinase activity
ATN04_RS07795	COG2610	gluconate transmembrane transporter activity
ATN04_RS07805	COG0343	queuine tRNA-ribosyltransferase activity
ATN04_RS07810	COG2409	Drug exporters of the RND superfamily
ATN04_RS07830	COG0287	Prephenate dehydrogenase
ATN04_RS07845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATN04_RS07870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ATN04_RS07870	COG1263	PTS System
ATN04_RS07870	COG2190	(PTS) system
ATN04_RS07875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ATN04_RS07875	COG1263	PTS System
ATN04_RS07885	COG0471	metal ion transport
ATN04_RS07945	COG0604	alcohol dehydrogenase
ATN04_RS07970	COG0803	Belongs to the bacterial solute-binding protein 9 family
ATN04_RS07975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATN04_RS07980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATN04_RS07985	COG1121	(ABC) transporter
ATN04_RS07990	COG0803	Belongs to the bacterial solute-binding protein 9 family
ATN04_RS07995	COG1216	Glycosyl transferase, family 2
ATN04_RS08025	COG0277	FAD linked oxidase domain protein
ATN04_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
ATN04_RS08060	COG3590	peptidase
ATN04_RS08070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATN04_RS08075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATN04_RS08095	COG2501	S4 domain
ATN04_RS08100	COG0393	Putative heavy-metal-binding
ATN04_RS08110	COG0519	Catalyzes the synthesis of GMP from XMP
ATN04_RS08120	COG1643	Atp-dependent helicase
ATN04_RS08135	COG0730	response to heat
ATN04_RS08145	COG3180	Ammonia monooxygenase
ATN04_RS08160	COG1846	Transcriptional regulator
ATN04_RS08190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ATN04_RS08215	COG3757	hydrolase, family 25
ATN04_RS08215	COG3409	Peptidoglycan-binding domain 1 protein
ATN04_RS08225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ATN04_RS08245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATN04_RS08255	COG0517	IMP dehydrogenase activity
ATN04_RS08255	COG1125	glycine betaine transport
ATN04_RS08310	COG0366	Alpha amylase catalytic
ATN04_RS08315	COG2239	Acts as a magnesium transporter
ATN04_RS08360	COG1716	ATPase activity
ATN04_RS08360	COG1716	ATPase activity
ATN04_RS08375	COG0772	Belongs to the SEDS family
ATN04_RS08380	COG0768	penicillin binding
ATN04_RS08385	COG0515	serine threonine protein kinase
ATN04_RS08390	COG0515	serine threonine protein kinase
ATN04_RS08390	COG2815	serine threonine protein kinase
ATN04_RS08400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ATN04_RS08405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS08410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS08415	COG1120	ATPase activity
ATN04_RS08460	COG1518	maintenance of DNA repeat elements
ATN04_RS08565	COG0187	DNA topoisomerase II activity
ATN04_RS08580	COG0592	DNA-directed DNA polymerase activity
ATN04_RS08590	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ATN04_RS08600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ATN04_RS08615	COG1192	Involved in chromosome partitioning
ATN04_RS08630	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATN04_RS08630	COG3409	Peptidoglycan-binding domain 1 protein
ATN04_RS08665	COG0617	tRNA 3'-terminal CCA addition
ATN04_RS08670	COG1678	Uncharacterized ACR, COG1678
ATN04_RS08675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ATN04_RS08680	COG1687	branched-chain amino acid
ATN04_RS08715	COG0135	phosphoribosylanthranilate isomerase activity
ATN04_RS08715	COG0134	indole-3-glycerol-phosphate synthase activity
ATN04_RS08725	COG0512	Glutamine amidotransferase of anthranilate synthase
ATN04_RS08730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATN04_RS08750	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ATN04_RS08765	COG3422	double-strand break repair
ATN04_RS08805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATN04_RS08810	COG4608	Belongs to the ABC transporter superfamily
ATN04_RS08815	COG0444	Belongs to the ABC transporter superfamily
ATN04_RS08820	COG0601	transmembrane transport
ATN04_RS08825	COG0747	negative chemotaxis
ATN04_RS08830	COG2186	Transcriptional regulator
ATN04_RS08845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATN04_RS08860	COG2197	response regulator
ATN04_RS08865	COG4585	Histidine kinase
ATN04_RS08890	COG1511	domain protein
ATN04_RS08900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATN04_RS08900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ATN04_RS08905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATN04_RS08910	COG0783	Belongs to the Dps family
ATN04_RS08915	COG0586	Pfam SNARE associated Golgi protein
ATN04_RS08950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATN04_RS08985	COG0305	Participates in initiation and elongation during chromosome replication
ATN04_RS08990	COG0477	Major facilitator Superfamily
ATN04_RS09005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATN04_RS09010	COG1842	Phage shock protein A
ATN04_RS09055	COG0564	pseudouridine synthase activity
ATN04_RS09080	COG0706	membrane insertase activity
ATN04_RS09085	COG3764	Sortase (surface protein transpeptidase)
ATN04_RS09100	COG2197	response regulator
ATN04_RS09135	COG2271	Major facilitator Superfamily
ATN04_RS09150	COG2814	Major facilitator Superfamily
ATN04_RS09155	COG0431	NADPH-dependent FMN reductase
ATN04_RS09220	COG1316	TRANSCRIPTIONal
ATN04_RS09230	COG0154	amidase activity
ATN04_RS09235	COG0077	Prephenate dehydratase
ATN04_RS09255	COG2188	Transcriptional regulator
ATN04_RS09270	COG0561	phosphatase activity
ATN04_RS09280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ATN04_RS09285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATN04_RS09300	COG2271	Major facilitator Superfamily
ATN04_RS09305	COG0584	glycerophosphoryl diester phosphodiesterase
ATN04_RS09325	COG1216	Glycosyl transferase, family 2
ATN04_RS09330	COG0671	phosphoesterase, PA-phosphatase related
ATN04_RS09335	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATN04_RS09340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ATN04_RS09345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATN04_RS09355	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATN04_RS09355	COG5479	isomerase activity
ATN04_RS09365	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ATN04_RS09370	COG0318	PFAM AMP-dependent synthetase and ligase
ATN04_RS09375	COG3321	synthase
ATN04_RS09375	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ATN04_RS09375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATN04_RS09380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATN04_RS09425	COG0500	methyltransferase
ATN04_RS09430	COG0438	transferase activity, transferring glycosyl groups
ATN04_RS09450	COG2755	lipolytic protein G-D-S-L family
ATN04_RS09450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ATN04_RS09455	COG4981	capsule polysaccharide biosynthetic process
ATN04_RS09465	COG1472	Belongs to the glycosyl hydrolase 3 family
ATN04_RS09475	COG1012	belongs to the aldehyde dehydrogenase family
ATN04_RS09490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ATN04_RS09510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATN04_RS09510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ATN04_RS09530	COG0831	urea catabolic process
ATN04_RS09535	COG0832	Belongs to the urease beta subunit family
ATN04_RS09540	COG0804	urea catabolic process
ATN04_RS09545	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ATN04_RS09550	COG0830	nickel cation binding
ATN04_RS09555	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ATN04_RS09560	COG0829	nickel cation binding
ATN04_RS09570	COG4139	cobalamin transport
ATN04_RS09575	COG1120	ATPase activity
ATN04_RS09610	COG0601	transmembrane transport
ATN04_RS09615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATN04_RS09645	COG0443	Heat shock 70 kDa protein
ATN04_RS09660	COG0789	Transcriptional regulator
ATN04_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
ATN04_RS09700	COG1136	(ABC) transporter
ATN04_RS09705	COG0577	efflux transmembrane transporter activity
ATN04_RS09705	COG1136	(ABC) transporter
ATN04_RS09725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATN04_RS09795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ATN04_RS09810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATN04_RS09825	COG0191	fructose-bisphosphate aldolase activity
ATN04_RS09860	COG4129	membrane
ATN04_RS09885	COG3005	denitrification pathway
ATN04_RS09890	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ATN04_RS09900	COG1333	cytochrome c biogenesis protein
ATN04_RS09905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATN04_RS09935	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ATN04_RS09940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ATN04_RS09960	COG0280	phosphate acetyltransferase
ATN04_RS09975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATN04_RS10000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATN04_RS10010	COG0456	acetyltransferase
ATN04_RS10015	COG0242	peptide deformylase activity
ATN04_RS10035	COG1051	belongs to the nudix hydrolase family
ATN04_RS10055	COG0651	ATP synthesis coupled electron transport
ATN04_RS10060	COG1006	Multisubunit Na H antiporter MnhC subunit
ATN04_RS10065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATN04_RS10065	COG2111	Na H antiporter
ATN04_RS10100	COG2801	Transposase and inactivated derivatives
ATN04_RS10115	COG2326	polyphosphate kinase activity
ATN04_RS10135	COG1301	dicarboxylic acid transport
ATN04_RS10140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATN04_RS10140	COG0425	Belongs to the sulfur carrier protein TusA family
ATN04_RS10145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ATN04_RS10150	COG2027	D-alanyl-D-alanine carboxypeptidase
ATN04_RS10160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATN04_RS10165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATN04_RS10170	COG0302	gtp cyclohydrolase
ATN04_RS10175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATN04_RS10205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATN04_RS10210	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ATN04_RS10215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ATN04_RS10220	COG1012	belongs to the aldehyde dehydrogenase family
ATN04_RS10225	COG1301	dicarboxylic acid transport
ATN04_RS10240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATN04_RS10255	COG1957	nucleoside hydrolase
ATN04_RS10260	COG0477	Major facilitator Superfamily
ATN04_RS10285	COG0288	reversible hydration of carbon dioxide
ATN04_RS10295	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ATN04_RS10310	COG2847	Copper chaperone PCu(A)C
ATN04_RS10315	COG1329	Transcriptional regulator
ATN04_RS10335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATN04_RS10345	COG1609	Transcriptional regulator
ATN04_RS10390	COG0028	Belongs to the TPP enzyme family
ATN04_RS10420	COG0745	RESPONSE REGULATOR receiver
ATN04_RS10425	COG2205	protein histidine kinase activity
ATN04_RS10435	COG0537	adenosine 5'-monophosphoramidase activity
ATN04_RS10450	COG0569	domain protein
ATN04_RS10455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATN04_RS10475	COG0386	Belongs to the glutathione peroxidase family
ATN04_RS10480	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATN04_RS10485	COG0047	phosphoribosylformylglycinamidine synthase activity
ATN04_RS10490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATN04_RS10500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATN04_RS10505	COG1780	Probably involved in ribonucleotide reductase function
ATN04_RS10530	COG0354	folic acid binding
ATN04_RS10545	COG1597	lipid kinase activity
ATN04_RS10575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATN04_RS10600	COG4988	ABC transporter
ATN04_RS10605	COG4988	ABC transporter
ATN04_RS10610	COG1294	oxidase, subunit
ATN04_RS10615	COG1271	oxidase subunit
ATN04_RS10635	COG0371	Dehydrogenase
ATN04_RS10655	COG1045	serine acetyltransferase
ATN04_RS10670	COG2197	response regulator