locus-tag	class	description
CpOVI2C_RS00015	COG0592	DNA-directed DNA polymerase activity
CpOVI2C_RS00030	COG0187	DNA topoisomerase II activity
CpOVI2C_RS00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CpOVI2C_RS00140	COG1120	ATPase activity
CpOVI2C_RS00145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS00150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS00155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CpOVI2C_RS00165	COG0515	serine threonine protein kinase
CpOVI2C_RS00165	COG2815	serine threonine protein kinase
CpOVI2C_RS00170	COG0515	serine threonine protein kinase
CpOVI2C_RS00175	COG0768	penicillin binding
CpOVI2C_RS00195	COG1716	ATPase activity
CpOVI2C_RS00195	COG1716	ATPase activity
CpOVI2C_RS00225	COG1120	ATPase activity
CpOVI2C_RS00230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS00235	COG2239	Acts as a magnesium transporter
CpOVI2C_RS00240	COG0366	Alpha amylase catalytic
CpOVI2C_RS00295	COG1125	glycine betaine transport
CpOVI2C_RS00295	COG0517	IMP dehydrogenase activity
CpOVI2C_RS00305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CpOVI2C_RS00325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CpOVI2C_RS00335	COG3409	Peptidoglycan-binding domain 1 protein
CpOVI2C_RS00335	COG3757	hydrolase, family 25
CpOVI2C_RS00360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CpOVI2C_RS00385	COG1846	Transcriptional regulator
CpOVI2C_RS00400	COG3180	Ammonia monooxygenase
CpOVI2C_RS00410	COG0730	response to heat
CpOVI2C_RS00425	COG1643	Atp-dependent helicase
CpOVI2C_RS00435	COG0519	Catalyzes the synthesis of GMP from XMP
CpOVI2C_RS00445	COG0393	Putative heavy-metal-binding
CpOVI2C_RS00450	COG2501	S4 domain
CpOVI2C_RS00475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CpOVI2C_RS00480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CpOVI2C_RS00490	COG3590	peptidase
CpOVI2C_RS00520	COG1028	Short-chain dehydrogenase reductase Sdr
CpOVI2C_RS00525	COG0277	FAD linked oxidase domain protein
CpOVI2C_RS00555	COG1216	Glycosyl transferase, family 2
CpOVI2C_RS00565	COG1121	(ABC) transporter
CpOVI2C_RS00570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpOVI2C_RS00575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpOVI2C_RS00580	COG0803	Belongs to the bacterial solute-binding protein 9 family
CpOVI2C_RS00605	COG0604	alcohol dehydrogenase
CpOVI2C_RS00630	COG0471	metal ion transport
CpOVI2C_RS00645	COG1263	PTS System
CpOVI2C_RS00645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CpOVI2C_RS00650	COG1263	PTS System
CpOVI2C_RS00650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CpOVI2C_RS00650	COG2190	(PTS) system
CpOVI2C_RS00675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CpOVI2C_RS00690	COG0287	Prephenate dehydrogenase
CpOVI2C_RS00710	COG2409	Drug exporters of the RND superfamily
CpOVI2C_RS00715	COG0343	queuine tRNA-ribosyltransferase activity
CpOVI2C_RS00725	COG2610	gluconate transmembrane transporter activity
CpOVI2C_RS00730	COG3265	gluconokinase activity
CpOVI2C_RS00735	COG1063	alcohol dehydrogenase
CpOVI2C_RS00740	COG1028	Short-chain dehydrogenase reductase Sdr
CpOVI2C_RS00755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CpOVI2C_RS00780	COG2610	gluconate transmembrane transporter activity
CpOVI2C_RS00785	COG2084	Dehydrogenase
CpOVI2C_RS00800	COG0179	Fumarylacetoacetate (FAA) hydrolase
CpOVI2C_RS00810	COG3442	glutamine amidotransferase
CpOVI2C_RS00815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CpOVI2C_RS00830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CpOVI2C_RS00835	COG2390	Transcriptional regulator
CpOVI2C_RS00840	COG0813	purine-nucleoside phosphorylase activity
CpOVI2C_RS00855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CpOVI2C_RS00885	COG0697	spore germination
CpOVI2C_RS00890	COG0527	aspartate kinase activity
CpOVI2C_RS00950	COG1840	ABC-type Fe3 transport system, periplasmic component
CpOVI2C_RS00955	COG2271	Major facilitator Superfamily
CpOVI2C_RS00965	COG3852	Histidine kinase
CpOVI2C_RS00985	COG0651	ATP synthesis coupled electron transport
CpOVI2C_RS00995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CpOVI2C_RS00995	COG2111	Na H antiporter
CpOVI2C_RS01015	COG4152	abc transporter atp-binding protein
CpOVI2C_RS01045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CpOVI2C_RS01070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CpOVI2C_RS01090	COG0494	nUDIX hydrolase
CpOVI2C_RS01160	COG1205	dead DEAH box helicase
CpOVI2C_RS01160	COG1111	helicase
CpOVI2C_RS01170	COG1754	DNA topoisomerase type I activity
CpOVI2C_RS01170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CpOVI2C_RS01175	COG1297	OPT oligopeptide transporter protein
CpOVI2C_RS01185	COG0470	DNA polymerase III
CpOVI2C_RS01200	COG0318	PFAM AMP-dependent synthetase and ligase
CpOVI2C_RS01210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CpOVI2C_RS01220	COG1088	dTDP-glucose 4,6-dehydratase activity
CpOVI2C_RS01230	COG1505	serine-type exopeptidase activity
CpOVI2C_RS01245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CpOVI2C_RS01250	COG3800	Transcriptional regulator
CpOVI2C_RS01250	COG1396	sequence-specific DNA binding
CpOVI2C_RS01260	COG1053	succinate dehydrogenase
CpOVI2C_RS01265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CpOVI2C_RS01275	COG2733	membrane
CpOVI2C_RS01285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CpOVI2C_RS01305	COG1882	Formate acetyltransferase
CpOVI2C_RS01325	COG0318	PFAM AMP-dependent synthetase and ligase
CpOVI2C_RS01340	COG5002	protein histidine kinase activity
CpOVI2C_RS01345	COG0745	RESPONSE REGULATOR receiver
CpOVI2C_RS01365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CpOVI2C_RS01385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CpOVI2C_RS01385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CpOVI2C_RS01415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CpOVI2C_RS01415	COG1648	precorrin-2 dehydrogenase activity
CpOVI2C_RS01430	COG2217	Heavy metal translocating P-type atpase
CpOVI2C_RS01440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CpOVI2C_RS01455	COG0406	alpha-ribazole phosphatase activity
CpOVI2C_RS01465	COG0785	Cytochrome C biogenesis protein
CpOVI2C_RS01475	COG0275	rRNA processing
CpOVI2C_RS01490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS01495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CpOVI2C_RS01525	COG3069	C4-dicarboxylate transmembrane transporter activity
CpOVI2C_RS01530	COG4948	Mandelate Racemase Muconate Lactonizing
CpOVI2C_RS01545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CpOVI2C_RS01545	COG0438	transferase activity, transferring glycosyl groups
CpOVI2C_RS01555	COG0039	L-malate dehydrogenase activity
CpOVI2C_RS01560	COG0644	oxidoreductase
CpOVI2C_RS01565	COG0142	geranyltranstransferase activity
CpOVI2C_RS01590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CpOVI2C_RS01615	COG3579	cysteine-type endopeptidase activity
CpOVI2C_RS01620	COG1902	pentaerythritol trinitrate reductase activity
CpOVI2C_RS01640	COG0803	Belongs to the bacterial solute-binding protein 9 family
CpOVI2C_RS01650	COG1121	(ABC) transporter
CpOVI2C_RS01655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpOVI2C_RS01685	COG2197	response regulator
CpOVI2C_RS01695	COG1131	(ABC) transporter
CpOVI2C_RS01710	COG0701	Predicted permease
CpOVI2C_RS01780	COG1302	Protein conserved in bacteria
CpOVI2C_RS01880	COG0814	amino acid
CpOVI2C_RS01885	COG1760	l-serine dehydratase
CpOVI2C_RS01890	COG0252	asparaginase activity
CpOVI2C_RS01945	COG1175	transmembrane transport
CpOVI2C_RS01950	COG3833	ABC-type maltose transport systems, permease component
CpOVI2C_RS01970	COG3842	ATPase activity
CpOVI2C_RS01975	COG0201	protein transport
CpOVI2C_RS02030	COG0203	ribosomal protein L17
CpOVI2C_RS02050	COG1404	Belongs to the peptidase S8 family
CpOVI2C_RS02060	COG1674	ftsk spoiiie
CpOVI2C_RS02115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CpOVI2C_RS02185	COG0516	GMP reductase activity
CpOVI2C_RS02230	COG2011	ABC-type metal ion transport system permease component
CpOVI2C_RS02240	COG1464	Belongs to the NlpA lipoprotein family
CpOVI2C_RS02245	COG1464	Belongs to the NlpA lipoprotein family
CpOVI2C_RS02265	COG0803	Belongs to the bacterial solute-binding protein 9 family
CpOVI2C_RS02270	COG1121	(ABC) transporter
CpOVI2C_RS02280	COG1321	iron dependent repressor
CpOVI2C_RS02280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpOVI2C_RS02285	COG1321	iron dependent repressor
CpOVI2C_RS02290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CpOVI2C_RS02295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CpOVI2C_RS02330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS02335	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CpOVI2C_RS02350	COG2838	Isocitrate dehydrogenase
CpOVI2C_RS02355	COG2814	Major facilitator Superfamily
CpOVI2C_RS02360	COG4978	Transcriptional regulator
CpOVI2C_RS02360	COG0789	Transcriptional regulator
CpOVI2C_RS02375	COG0180	Tryptophanyl-tRNA synthetase
CpOVI2C_RS02380	COG1295	ribonuclease BN
CpOVI2C_RS02385	COG1686	Belongs to the peptidase S11 family
CpOVI2C_RS02420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CpOVI2C_RS02425	COG1473	amidohydrolase
CpOVI2C_RS02425	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CpOVI2C_RS02440	COG2814	Major facilitator Superfamily
CpOVI2C_RS02450	COG4770	biotin carboxylase activity
CpOVI2C_RS02455	COG2897	thiosulfate sulfurtransferase activity
CpOVI2C_RS02465	COG2755	lipolytic protein G-D-S-L family
CpOVI2C_RS02465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CpOVI2C_RS02475	COG0424	maF-like protein
CpOVI2C_RS02480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CpOVI2C_RS02485	COG1609	Transcriptional regulator
CpOVI2C_RS02495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CpOVI2C_RS02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CpOVI2C_RS02505	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CpOVI2C_RS02505	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CpOVI2C_RS02555	COG1316	TRANSCRIPTIONal
CpOVI2C_RS02565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CpOVI2C_RS02600	COG1482	cell wall glycoprotein biosynthetic process
CpOVI2C_RS02625	COG0745	RESPONSE REGULATOR receiver
CpOVI2C_RS02630	COG5002	protein histidine kinase activity
CpOVI2C_RS02645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CpOVI2C_RS02685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CpOVI2C_RS02690	COG2135	peptidase activity
CpOVI2C_RS02695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CpOVI2C_RS02730	COG0513	Belongs to the DEAD box helicase family
CpOVI2C_RS02755	COG0210	DNA helicase
CpOVI2C_RS02765	COG2816	NAD+ diphosphatase activity
CpOVI2C_RS02790	COG3480	Lon protease (S16) C-terminal proteolytic domain
CpOVI2C_RS02915	COG0483	inositol monophosphate 1-phosphatase activity
CpOVI2C_RS02920	COG0483	inositol monophosphate 1-phosphatase activity
CpOVI2C_RS02935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CpOVI2C_RS02945	COG2884	Cell division ATP-binding protein ftsE
CpOVI2C_RS02950	COG2177	Part of the ABC transporter FtsEX involved in
CpOVI2C_RS02965	COG0288	reversible hydration of carbon dioxide
CpOVI2C_RS03015	COG0564	pseudouridine synthase activity
CpOVI2C_RS03040	COG0706	membrane insertase activity
CpOVI2C_RS03045	COG3764	Sortase (surface protein transpeptidase)
CpOVI2C_RS03060	COG2197	response regulator
CpOVI2C_RS03080	COG5650	phosphatidylinositol metabolic process
CpOVI2C_RS03095	COG2271	Major facilitator Superfamily
CpOVI2C_RS03115	COG2814	Major facilitator Superfamily
CpOVI2C_RS03120	COG0431	NADPH-dependent FMN reductase
CpOVI2C_RS03150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CpOVI2C_RS03180	COG1316	TRANSCRIPTIONal
CpOVI2C_RS03190	COG0154	amidase activity
CpOVI2C_RS03215	COG2188	Transcriptional regulator
CpOVI2C_RS03230	COG0561	phosphatase activity
CpOVI2C_RS03240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CpOVI2C_RS03245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS03260	COG2271	Major facilitator Superfamily
CpOVI2C_RS03265	COG0584	glycerophosphoryl diester phosphodiesterase
CpOVI2C_RS03275	COG0671	phosphoesterase, PA-phosphatase related
CpOVI2C_RS03285	COG1216	Glycosyl transferase, family 2
CpOVI2C_RS03290	COG0671	phosphoesterase, PA-phosphatase related
CpOVI2C_RS03295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CpOVI2C_RS03300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CpOVI2C_RS03315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CpOVI2C_RS03315	COG5479	isomerase activity
CpOVI2C_RS03325	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CpOVI2C_RS03330	COG0318	PFAM AMP-dependent synthetase and ligase
CpOVI2C_RS03335	COG3321	synthase
CpOVI2C_RS03335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CpOVI2C_RS03335	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CpOVI2C_RS03340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CpOVI2C_RS03385	COG0500	methyltransferase
CpOVI2C_RS03390	COG0438	transferase activity, transferring glycosyl groups
CpOVI2C_RS03405	COG2755	lipolytic protein G-D-S-L family
CpOVI2C_RS03405	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CpOVI2C_RS03410	COG4981	capsule polysaccharide biosynthetic process
CpOVI2C_RS03420	COG1472	Belongs to the glycosyl hydrolase 3 family
CpOVI2C_RS03430	COG1012	belongs to the aldehyde dehydrogenase family
CpOVI2C_RS03445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CpOVI2C_RS03465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CpOVI2C_RS03465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CpOVI2C_RS03490	COG0831	urea catabolic process
CpOVI2C_RS03495	COG0832	Belongs to the urease beta subunit family
CpOVI2C_RS03500	COG0804	urea catabolic process
CpOVI2C_RS03505	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CpOVI2C_RS03510	COG0830	nickel cation binding
CpOVI2C_RS03515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CpOVI2C_RS03520	COG0829	nickel cation binding
CpOVI2C_RS03530	COG4139	cobalamin transport
CpOVI2C_RS03535	COG1120	ATPase activity
CpOVI2C_RS03550	COG2181	nitrate reductase activity
CpOVI2C_RS03550	COG0247	lactate metabolic process
CpOVI2C_RS03575	COG0601	transmembrane transport
CpOVI2C_RS03610	COG0443	Heat shock 70 kDa protein
CpOVI2C_RS03625	COG0789	Transcriptional regulator
CpOVI2C_RS03665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CpOVI2C_RS03670	COG1136	(ABC) transporter
CpOVI2C_RS03675	COG1136	(ABC) transporter
CpOVI2C_RS03675	COG0577	efflux transmembrane transporter activity
CpOVI2C_RS03725	COG1131	(ABC) transporter
CpOVI2C_RS03765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CpOVI2C_RS03780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CpOVI2C_RS03795	COG0191	fructose-bisphosphate aldolase activity
CpOVI2C_RS03840	COG4129	membrane
CpOVI2C_RS03855	COG3005	denitrification pathway
CpOVI2C_RS03860	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CpOVI2C_RS03870	COG1333	cytochrome c biogenesis protein
CpOVI2C_RS03875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CpOVI2C_RS03905	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CpOVI2C_RS03910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CpOVI2C_RS03930	COG0280	phosphate acetyltransferase
CpOVI2C_RS03945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CpOVI2C_RS03970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CpOVI2C_RS03980	COG0456	acetyltransferase
CpOVI2C_RS03985	COG0242	peptide deformylase activity
CpOVI2C_RS04005	COG1051	belongs to the nudix hydrolase family
CpOVI2C_RS04025	COG0651	ATP synthesis coupled electron transport
CpOVI2C_RS04030	COG1006	Multisubunit Na H antiporter MnhC subunit
CpOVI2C_RS04035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CpOVI2C_RS04035	COG2111	Na H antiporter
CpOVI2C_RS04080	COG2326	polyphosphate kinase activity
CpOVI2C_RS04085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CpOVI2C_RS04105	COG1301	dicarboxylic acid transport
CpOVI2C_RS04110	COG0425	Belongs to the sulfur carrier protein TusA family
CpOVI2C_RS04110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CpOVI2C_RS04115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CpOVI2C_RS04120	COG2027	D-alanyl-D-alanine carboxypeptidase
CpOVI2C_RS04130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CpOVI2C_RS04135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CpOVI2C_RS04140	COG0302	gtp cyclohydrolase
CpOVI2C_RS04145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CpOVI2C_RS04175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CpOVI2C_RS04180	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CpOVI2C_RS04185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CpOVI2C_RS04190	COG1012	belongs to the aldehyde dehydrogenase family
CpOVI2C_RS04195	COG1301	dicarboxylic acid transport
CpOVI2C_RS04210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CpOVI2C_RS04225	COG1957	nucleoside hydrolase
CpOVI2C_RS04230	COG0477	Major facilitator Superfamily
CpOVI2C_RS04240	COG0542	response to heat
CpOVI2C_RS04260	COG0288	reversible hydration of carbon dioxide
CpOVI2C_RS04270	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CpOVI2C_RS04285	COG2847	Copper chaperone PCu(A)C
CpOVI2C_RS04290	COG1329	Transcriptional regulator
CpOVI2C_RS04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CpOVI2C_RS04320	COG1609	Transcriptional regulator
CpOVI2C_RS04370	COG0028	Belongs to the TPP enzyme family
CpOVI2C_RS04400	COG0745	RESPONSE REGULATOR receiver
CpOVI2C_RS04405	COG2205	protein histidine kinase activity
CpOVI2C_RS04415	COG0537	adenosine 5'-monophosphoramidase activity
CpOVI2C_RS04420	COG0151	Belongs to the GarS family
CpOVI2C_RS04425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CpOVI2C_RS04430	COG0569	domain protein
CpOVI2C_RS04435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CpOVI2C_RS04455	COG0386	Belongs to the glutathione peroxidase family
CpOVI2C_RS04460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CpOVI2C_RS04465	COG0047	phosphoribosylformylglycinamidine synthase activity
CpOVI2C_RS04470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CpOVI2C_RS04480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CpOVI2C_RS04485	COG1780	Probably involved in ribonucleotide reductase function
CpOVI2C_RS04510	COG0354	folic acid binding
CpOVI2C_RS04525	COG1597	lipid kinase activity
CpOVI2C_RS04555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CpOVI2C_RS04580	COG1132	(ABC) transporter
CpOVI2C_RS04585	COG4988	ABC transporter
CpOVI2C_RS04590	COG1294	oxidase, subunit
CpOVI2C_RS04595	COG1271	oxidase subunit
CpOVI2C_RS04635	COG1045	serine acetyltransferase
CpOVI2C_RS04650	COG2197	response regulator
CpOVI2C_RS04685	COG1136	(ABC) transporter
CpOVI2C_RS04685	COG0577	efflux transmembrane transporter activity
CpOVI2C_RS04690	COG0577	efflux transmembrane transporter activity
CpOVI2C_RS04690	COG1136	(ABC) transporter
CpOVI2C_RS04705	COG0033	Phosphoglucomutase
CpOVI2C_RS04775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CpOVI2C_RS04795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CpOVI2C_RS04805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CpOVI2C_RS04850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CpOVI2C_RS04875	COG1234	tRNA 3'-trailer cleavage
CpOVI2C_RS04925	COG2197	response regulator
CpOVI2C_RS04970	COG1335	isochorismatase
CpOVI2C_RS04975	COG2130	NADP-dependent
CpOVI2C_RS04985	COG1376	ErfK ybiS ycfS ynhG family protein
CpOVI2C_RS05010	COG0604	alcohol dehydrogenase
CpOVI2C_RS05030	COG1966	Carbon starvation protein
CpOVI2C_RS05035	COG3336	cytochrome c oxidase
CpOVI2C_RS05040	COG1131	(ABC) transporter
CpOVI2C_RS05120	COG0668	transmembrane transport
CpOVI2C_RS05130	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CpOVI2C_RS05165	COG0544	peptidyl-prolyl cis-trans isomerase activity
CpOVI2C_RS05205	COG0285	dihydrofolate synthase activity
CpOVI2C_RS05215	COG2423	ornithine cyclodeaminase activity
CpOVI2C_RS05230	COG1530	ribonuclease E activity
CpOVI2C_RS05255	COG2985	domain, Protein
CpOVI2C_RS05255	COG0569	domain protein
CpOVI2C_RS05260	COG2832	Protein of unknown function (DUF454)
CpOVI2C_RS05275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CpOVI2C_RS05285	COG0406	alpha-ribazole phosphatase activity
CpOVI2C_RS05290	COG1307	EDD domain protein, DegV family
CpOVI2C_RS05315	COG1280	lysine exporter protein (LysE YggA)
CpOVI2C_RS05340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CpOVI2C_RS05345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CpOVI2C_RS05365	COG0601	transmembrane transport
CpOVI2C_RS05375	COG2391	methyltransferase activity
CpOVI2C_RS05380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CpOVI2C_RS05390	COG4172	Belongs to the ABC transporter superfamily
CpOVI2C_RS05395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CpOVI2C_RS05400	COG0601	transmembrane transport
CpOVI2C_RS05405	COG0747	negative chemotaxis
CpOVI2C_RS05420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CpOVI2C_RS05430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CpOVI2C_RS05435	COG1114	Component of the transport system for branched-chain amino acids
CpOVI2C_RS05490	COG1022	Amp-dependent synthetase and ligase
CpOVI2C_RS05545	COG1381	Involved in DNA repair and RecF pathway recombination
CpOVI2C_RS05575	COG0423	glycine-tRNA ligase activity
CpOVI2C_RS05645	COG2860	membrane
CpOVI2C_RS05675	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CpOVI2C_RS05715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CpOVI2C_RS05715	COG3323	Protein of unknown function (DUF1653)
CpOVI2C_RS05735	COG0557	exoribonuclease II activity
CpOVI2C_RS05760	COG0174	glutamine synthetase
CpOVI2C_RS05785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CpOVI2C_RS05795	COG2056	Na+-H+ antiporter family
CpOVI2C_RS05940	COG0174	glutamine synthetase
CpOVI2C_RS05970	COG0509	glycine decarboxylation via glycine cleavage system
CpOVI2C_RS05975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CpOVI2C_RS05980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CpOVI2C_RS05980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CpOVI2C_RS05985	COG0508	dehydrogenase complex catalyzes the overall conversion of
CpOVI2C_RS06000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CpOVI2C_RS06010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CpOVI2C_RS06015	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CpOVI2C_RS06065	COG0791	NLP P60 protein
CpOVI2C_RS06075	COG0438	transferase activity, transferring glycosyl groups
CpOVI2C_RS06080	COG1940	carbohydrate kinase activity
CpOVI2C_RS06100	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CpOVI2C_RS06105	COG0515	serine threonine protein kinase
CpOVI2C_RS06105	COG2815	serine threonine protein kinase
CpOVI2C_RS06120	COG0142	geranyltranstransferase activity
CpOVI2C_RS06165	COG0768	penicillin binding
CpOVI2C_RS06170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CpOVI2C_RS06200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CpOVI2C_RS06210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CpOVI2C_RS06215	COG1496	oxidoreductase activity
CpOVI2C_RS06225	COG1799	cell septum assembly
CpOVI2C_RS06235	COG3599	regulation of cell shape
CpOVI2C_RS06255	COG0252	asparaginase activity
CpOVI2C_RS06270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CpOVI2C_RS06295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CpOVI2C_RS06300	COG1739	Uncharacterized protein family UPF0029
CpOVI2C_RS06325	COG2176	DNA-directed DNA polymerase activity
CpOVI2C_RS06390	COG0483	inositol monophosphate 1-phosphatase activity
CpOVI2C_RS06410	COG0134	indole-3-glycerol-phosphate synthase activity
CpOVI2C_RS06420	COG0469	pyruvate kinase activity
CpOVI2C_RS06430	COG0058	SHG alpha-glucan phosphorylase activity
CpOVI2C_RS06455	COG1929	Belongs to the glycerate kinase type-1 family
CpOVI2C_RS06460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CpOVI2C_RS06465	COG0686	Belongs to the AlaDH PNT family
CpOVI2C_RS06490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CpOVI2C_RS06495	COG1115	amino acid carrier protein
CpOVI2C_RS06525	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CpOVI2C_RS06545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CpOVI2C_RS06550	COG0336	Belongs to the RNA methyltransferase TrmD family
CpOVI2C_RS06560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CpOVI2C_RS06560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpOVI2C_RS06560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpOVI2C_RS06575	COG0681	Belongs to the peptidase S26 family
CpOVI2C_RS06600	COG4974	Belongs to the 'phage' integrase family
CpOVI2C_RS06660	COG0750	zinc metalloprotease
CpOVI2C_RS06725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CpOVI2C_RS06725	COG2169	Transcriptional regulator
CpOVI2C_RS06730	COG0523	cobalamin synthesis protein
CpOVI2C_RS06735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CpOVI2C_RS06740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CpOVI2C_RS06740	COG1648	precorrin-2 dehydrogenase activity
CpOVI2C_RS06745	COG3022	response to hydroperoxide
CpOVI2C_RS06790	COG0534	Mate efflux family protein
CpOVI2C_RS06795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CpOVI2C_RS06805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CpOVI2C_RS06845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CpOVI2C_RS06855	COG1674	ftsk spoiiie
CpOVI2C_RS06880	COG1396	sequence-specific DNA binding
CpOVI2C_RS06885	COG1842	Phage shock protein A
CpOVI2C_RS06895	COG1122	ATPase activity
CpOVI2C_RS06900	COG1268	BioY protein
CpOVI2C_RS06910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CpOVI2C_RS06915	COG2137	regulation of response to DNA damage stimulus
CpOVI2C_RS06935	COG1196	nuclear chromosome segregation
CpOVI2C_RS06950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CpOVI2C_RS06965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CpOVI2C_RS06970	COG2233	PERMEase
CpOVI2C_RS06980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CpOVI2C_RS06985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CpOVI2C_RS06995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpOVI2C_RS06995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpOVI2C_RS06995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CpOVI2C_RS07000	COG1105	Belongs to the carbohydrate kinase PfkB family
CpOVI2C_RS07005	COG1349	DNA-binding transcription factor activity
CpOVI2C_RS07010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CpOVI2C_RS07015	COG1349	DNA-binding transcription factor activity
CpOVI2C_RS07035	COG1643	Atp-dependent helicase
CpOVI2C_RS07050	COG0450	alkyl hydroperoxide reductase
CpOVI2C_RS07055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CpOVI2C_RS07095	COG2890	protein-(glutamine-N5) methyltransferase activity
CpOVI2C_RS07180	COG3253	May function as heme-dependent peroxidase
CpOVI2C_RS07185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CpOVI2C_RS07240	COG2837	iron assimilation
CpOVI2C_RS07255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CpOVI2C_RS07260	COG1560	Kdo2-lipid A biosynthetic process
CpOVI2C_RS07275	COG0156	8-amino-7-oxononanoate synthase activity
CpOVI2C_RS07290	COG1946	Acyl-CoA thioesterase
CpOVI2C_RS07320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CpOVI2C_RS07325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CpOVI2C_RS07340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CpOVI2C_RS07355	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CpOVI2C_RS07360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CpOVI2C_RS07385	COG1760	l-serine dehydratase
CpOVI2C_RS07440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CpOVI2C_RS07460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CpOVI2C_RS07465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CpOVI2C_RS07470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CpOVI2C_RS07475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CpOVI2C_RS07480	COG0006	proline dipeptidase activity
CpOVI2C_RS07505	COG1090	epimerase
CpOVI2C_RS07520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CpOVI2C_RS07530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CpOVI2C_RS07570	COG0242	peptide deformylase activity
CpOVI2C_RS07585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CpOVI2C_RS07615	COG0322	excinuclease ABC activity
CpOVI2C_RS07625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CpOVI2C_RS07635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CpOVI2C_RS07655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CpOVI2C_RS07675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CpOVI2C_RS07680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CpOVI2C_RS07725	COG0396	ATPase activity
CpOVI2C_RS07735	COG0822	iron-sulfur transferase activity
CpOVI2C_RS07740	COG2151	metal-sulfur cluster biosynthetic enzyme
CpOVI2C_RS07765	COG2848	UPF0210 protein
CpOVI2C_RS07795	COG3883	PFAM NLP P60 protein
CpOVI2C_RS07795	COG0791	NLP P60 protein
CpOVI2C_RS07860	COG0488	(ABC) transporter
CpOVI2C_RS07865	COG3842	ATPase activity
CpOVI2C_RS07875	COG2376	Dihydroxyacetone kinase
CpOVI2C_RS07880	COG1461	Dihydroxyacetone kinase
CpOVI2C_RS07905	COG0167	dihydroorotate dehydrogenase activity
CpOVI2C_RS07915	COG0667	Aldo Keto reductase
CpOVI2C_RS07935	COG1410	methionine synthase
CpOVI2C_RS07935	COG0646	methionine synthase
CpOVI2C_RS07955	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CpOVI2C_RS07960	COG1027	Aspartate ammonia-lyase
CpOVI2C_RS07980	COG1362	aminopeptidase activity
CpOVI2C_RS07995	COG4122	O-methyltransferase activity
CpOVI2C_RS08015	COG2378	regulation of single-species biofilm formation
CpOVI2C_RS08025	COG0805	protein transport
CpOVI2C_RS08040	COG0300	oxidoreductase activity
CpOVI2C_RS08090	COG0463	Glycosyl transferase, family 2
CpOVI2C_RS08115	COG0477	Major facilitator Superfamily
CpOVI2C_RS08135	COG0598	Magnesium transport protein CorA
CpOVI2C_RS08145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CpOVI2C_RS08150	COG0513	Belongs to the DEAD box helicase family
CpOVI2C_RS08155	COG1253	flavin adenine dinucleotide binding
CpOVI2C_RS08195	COG0653	protein targeting
CpOVI2C_RS08205	COG3012	SEC-C Motif Domain Protein
CpOVI2C_RS08230	COG3547	Transposase (IS116 IS110 IS902 family)
CpOVI2C_RS08240	COG4264	IucA IucC family
CpOVI2C_RS08245	COG1120	ATPase activity
CpOVI2C_RS08250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS08255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS08260	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CpOVI2C_RS08265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CpOVI2C_RS08270	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CpOVI2C_RS08275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CpOVI2C_RS08280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CpOVI2C_RS08285	COG1160	GTP binding
CpOVI2C_RS08300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CpOVI2C_RS08310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CpOVI2C_RS08315	COG3104	oligopeptide transport
CpOVI2C_RS08335	COG4974	Belongs to the 'phage' integrase family
CpOVI2C_RS08340	COG0494	nUDIX hydrolase
CpOVI2C_RS08370	COG0647	UMP catabolic process
CpOVI2C_RS08405	COG2835	tetraacyldisaccharide 4'-kinase activity
CpOVI2C_RS08410	COG0165	Argininosuccinate lyase
CpOVI2C_RS08430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CpOVI2C_RS08445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CpOVI2C_RS08460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CpOVI2C_RS08475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CpOVI2C_RS08490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CpOVI2C_RS08500	COG3973	AAA domain
CpOVI2C_RS08520	COG0237	dephospho-CoA kinase activity
CpOVI2C_RS08530	COG0539	negative regulation of cytoplasmic translation
CpOVI2C_RS08535	COG2226	methyltransferase
CpOVI2C_RS08560	COG0765	amino acid transport
CpOVI2C_RS08585	COG0742	ribosomal rna small subunit methyltransferase
CpOVI2C_RS08590	COG0511	ligase activity, forming carbon-carbon bonds
CpOVI2C_RS08600	COG1461	Dihydroxyacetone kinase
CpOVI2C_RS08605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CpOVI2C_RS08610	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CpOVI2C_RS08630	COG0494	nUDIX hydrolase
CpOVI2C_RS08630	COG0406	alpha-ribazole phosphatase activity
CpOVI2C_RS08665	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CpOVI2C_RS08695	COG0179	Fumarylacetoacetate (FAA) hydrolase
CpOVI2C_RS08715	COG0473	3-isopropylmalate dehydrogenase activity
CpOVI2C_RS08755	COG0668	transmembrane transport
CpOVI2C_RS08780	COG0583	DNA-binding transcription factor activity
CpOVI2C_RS08790	COG0667	Aldo Keto reductase
CpOVI2C_RS08800	COG0205	6-phosphofructokinase activity
CpOVI2C_RS08810	COG1120	ATPase activity
CpOVI2C_RS08815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpOVI2C_RS08880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CpOVI2C_RS08900	COG1119	ATPase activity
CpOVI2C_RS08925	COG0346	lactoylglutathione lyase activity
CpOVI2C_RS08970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CpOVI2C_RS08975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CpOVI2C_RS08980	COG0356	it plays a direct role in the translocation of protons across the membrane
CpOVI2C_RS09030	COG0460	homoserine dehydrogenase
CpOVI2C_RS09035	COG0019	diaminopimelate decarboxylase activity
CpOVI2C_RS09045	COG1620	l-lactate permease
CpOVI2C_RS09050	COG0247	lactate metabolic process
CpOVI2C_RS09055	COG1139	Iron-sulfur cluster binding protein
CpOVI2C_RS09060	COG1556	Lactate utilization protein
CpOVI2C_RS09090	COG1846	Transcriptional regulator
CpOVI2C_RS09115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CpOVI2C_RS09120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CpOVI2C_RS09150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CpOVI2C_RS09170	COG2017	converts alpha-aldose to the beta-anomer
CpOVI2C_RS09190	COG2272	Belongs to the type-B carboxylesterase lipase family
CpOVI2C_RS09195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CpOVI2C_RS09205	COG1132	(ABC) transporter
CpOVI2C_RS09210	COG0567	Dehydrogenase, E1 component
CpOVI2C_RS09210	COG0508	dehydrogenase complex catalyzes the overall conversion of
CpOVI2C_RS09220	COG2239	Acts as a magnesium transporter
CpOVI2C_RS09250	COG4122	O-methyltransferase activity
CpOVI2C_RS09260	COG0297	glycogen (starch) synthase activity
CpOVI2C_RS09265	COG3527	Alpha-acetolactate decarboxylase
CpOVI2C_RS09290	COG0463	Glycosyl transferase, family 2
CpOVI2C_RS09295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CpOVI2C_RS09300	COG1611	Belongs to the LOG family
CpOVI2C_RS09305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CpOVI2C_RS09315	COG1113	amino acid transport
CpOVI2C_RS09325	COG1113	amino acid transport
CpOVI2C_RS09360	COG4166	transmembrane transport
CpOVI2C_RS09365	COG1217	gtp-binding protein TYPA
CpOVI2C_RS09395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CpOVI2C_RS09400	COG0601	transmembrane transport
CpOVI2C_RS09405	COG4166	transmembrane transport
CpOVI2C_RS09415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CpOVI2C_RS09425	COG1122	ATPase activity
CpOVI2C_RS09430	COG4721	ABC-type cobalt transport system, permease component
CpOVI2C_RS09440	COG2354	Protein conserved in bacteria
CpOVI2C_RS09445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CpOVI2C_RS09455	COG1132	(ABC) transporter
CpOVI2C_RS09460	COG2824	Alkylphosphonate utilization operon protein PhnA
CpOVI2C_RS09475	COG0012	GTP binding
CpOVI2C_RS09510	COG1494	fructose-1,6-bisphosphatase
CpOVI2C_RS09515	COG0114	fumarate hydratase activity
CpOVI2C_RS09585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CpOVI2C_RS09650	COG3956	TIGRFAM MazG family protein
CpOVI2C_RS09655	COG0531	amino acid
CpOVI2C_RS09665	COG1309	transcriptional regulator
CpOVI2C_RS09680	COG2132	Multicopper oxidase
CpOVI2C_RS09685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CpOVI2C_RS09690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CpOVI2C_RS09695	COG1523	belongs to the glycosyl hydrolase 13 family
CpOVI2C_RS09715	COG2070	2-Nitropropane dioxygenase
CpOVI2C_RS09720	COG0193	aminoacyl-tRNA hydrolase activity
CpOVI2C_RS09730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CpOVI2C_RS09735	COG0596	Alpha beta hydrolase
CpOVI2C_RS09775	COG2326	polyphosphate kinase activity
CpOVI2C_RS09790	COG0488	(ABC) transporter
CpOVI2C_RS09805	COG3583	domain protein
CpOVI2C_RS09810	COG0084	hydrolase, TatD family'
CpOVI2C_RS09825	COG3949	Membrane
CpOVI2C_RS09830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CpOVI2C_RS09840	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CpOVI2C_RS09850	COG2259	Doxx family
CpOVI2C_RS09870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CpOVI2C_RS09895	COG0315	cyclic pyranopterin monophosphate synthase activity
CpOVI2C_RS09895	COG0521	Mo-molybdopterin cofactor biosynthetic process
CpOVI2C_RS09900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CpOVI2C_RS09905	COG2205	protein histidine kinase activity
CpOVI2C_RS09910	COG0745	RESPONSE REGULATOR receiver
CpOVI2C_RS09920	COG0254	rRNA binding
CpOVI2C_RS09950	COG1309	transcriptional regulator
CpOVI2C_RS09960	COG0765	amino acid transport
CpOVI2C_RS09965	COG0765	amino acid transport
CpOVI2C_RS09970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CpOVI2C_RS09975	COG1126	abc transporter atp-binding protein
CpOVI2C_RS10025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CpOVI2C_RS10035	COG1201	RNA secondary structure unwinding
CpOVI2C_RS10045	COG1218	3'(2'),5'-bisphosphate nucleotidase
CpOVI2C_RS10060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CpOVI2C_RS10085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CpOVI2C_RS10100	COG4166	transmembrane transport
CpOVI2C_RS10115	COG0019	diaminopimelate decarboxylase activity
CpOVI2C_RS10120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CpOVI2C_RS10125	COG0534	Mate efflux family protein
CpOVI2C_RS10140	COG3757	hydrolase, family 25
CpOVI2C_RS10150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CpOVI2C_RS10160	COG1024	Enoyl-CoA hydratase
CpOVI2C_RS10165	COG0656	L-ascorbic acid biosynthetic process
CpOVI2C_RS10180	COG0545	Peptidyl-prolyl cis-trans isomerase
CpOVI2C_RS10185	COG0372	Belongs to the citrate synthase family
CpOVI2C_RS10205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CpOVI2C_RS10210	COG2252	PERMEase
CpOVI2C_RS10235	COG1652	LysM domain
CpOVI2C_RS10245	COG1061	Type III restriction enzyme res subunit
CpOVI2C_RS10285	COG1131	(ABC) transporter
CpOVI2C_RS10300	COG1842	Phage shock protein A
CpOVI2C_RS10305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CpOVI2C_RS10320	COG0477	Major facilitator Superfamily
CpOVI2C_RS10325	COG0305	Participates in initiation and elongation during chromosome replication
CpOVI2C_RS10330	COG3387	PFAM Glycoside hydrolase 15-related
CpOVI2C_RS10345	COG0629	single-stranded DNA binding
CpOVI2C_RS10370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CpOVI2C_RS10390	COG0300	oxidoreductase activity
CpOVI2C_RS10405	COG0586	Pfam SNARE associated Golgi protein
CpOVI2C_RS10410	COG0783	Belongs to the Dps family
CpOVI2C_RS10415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CpOVI2C_RS10420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CpOVI2C_RS10420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CpOVI2C_RS10430	COG1511	domain protein
CpOVI2C_RS10440	COG1136	(ABC) transporter
CpOVI2C_RS10440	COG0577	efflux transmembrane transporter activity
CpOVI2C_RS10460	COG4585	Histidine kinase
CpOVI2C_RS10465	COG2197	response regulator
CpOVI2C_RS10480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CpOVI2C_RS10495	COG2186	Transcriptional regulator
CpOVI2C_RS10500	COG0747	negative chemotaxis
CpOVI2C_RS10505	COG0601	transmembrane transport
CpOVI2C_RS10510	COG0444	Belongs to the ABC transporter superfamily
CpOVI2C_RS10515	COG4608	Belongs to the ABC transporter superfamily
CpOVI2C_RS10520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CpOVI2C_RS10560	COG3422	double-strand break repair
CpOVI2C_RS10575	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CpOVI2C_RS10595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CpOVI2C_RS10600	COG0512	Glutamine amidotransferase of anthranilate synthase
CpOVI2C_RS10610	COG0134	indole-3-glycerol-phosphate synthase activity
CpOVI2C_RS10610	COG0135	phosphoribosylanthranilate isomerase activity
CpOVI2C_RS10645	COG1687	branched-chain amino acid
CpOVI2C_RS10650	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CpOVI2C_RS10655	COG1678	Uncharacterized ACR, COG1678
CpOVI2C_RS10660	COG0617	tRNA 3'-terminal CCA addition
CpOVI2C_RS10695	COG0860	N-Acetylmuramoyl-L-alanine amidase
CpOVI2C_RS10695	COG3409	Peptidoglycan-binding domain 1 protein
CpOVI2C_RS10710	COG1192	Involved in chromosome partitioning
CpOVI2C_RS10725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CpOVI2C_RS10735	COG0230	Belongs to the bacterial ribosomal protein bL34 family