locus-tag	class	description
CpPA07_RS00010	COG0592	DNA-directed DNA polymerase activity
CpPA07_RS00025	COG0187	DNA topoisomerase II activity
CpPA07_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CpPA07_RS00135	COG1120	ATPase activity
CpPA07_RS00140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS00145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS00150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CpPA07_RS00160	COG2815	serine threonine protein kinase
CpPA07_RS00160	COG0515	serine threonine protein kinase
CpPA07_RS00165	COG0515	serine threonine protein kinase
CpPA07_RS00170	COG0768	penicillin binding
CpPA07_RS00190	COG1716	ATPase activity
CpPA07_RS00190	COG1716	ATPase activity
CpPA07_RS00220	COG1120	ATPase activity
CpPA07_RS00225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS00230	COG2239	Acts as a magnesium transporter
CpPA07_RS00235	COG0366	Alpha amylase catalytic
CpPA07_RS00290	COG0517	IMP dehydrogenase activity
CpPA07_RS00290	COG1125	glycine betaine transport
CpPA07_RS00300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CpPA07_RS00320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CpPA07_RS00330	COG3409	Peptidoglycan-binding domain 1 protein
CpPA07_RS00330	COG3757	hydrolase, family 25
CpPA07_RS00355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CpPA07_RS00380	COG1846	Transcriptional regulator
CpPA07_RS00395	COG3180	Ammonia monooxygenase
CpPA07_RS00405	COG0730	response to heat
CpPA07_RS00420	COG1643	Atp-dependent helicase
CpPA07_RS00430	COG0519	Catalyzes the synthesis of GMP from XMP
CpPA07_RS00440	COG0393	Putative heavy-metal-binding
CpPA07_RS00445	COG2501	S4 domain
CpPA07_RS00470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CpPA07_RS00475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CpPA07_RS00485	COG3590	peptidase
CpPA07_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
CpPA07_RS00520	COG0277	FAD linked oxidase domain protein
CpPA07_RS00550	COG1216	Glycosyl transferase, family 2
CpPA07_RS00560	COG1121	(ABC) transporter
CpPA07_RS00565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpPA07_RS00570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpPA07_RS00575	COG0803	Belongs to the bacterial solute-binding protein 9 family
CpPA07_RS00600	COG0604	alcohol dehydrogenase
CpPA07_RS00625	COG0471	metal ion transport
CpPA07_RS00640	COG1263	PTS System
CpPA07_RS00640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CpPA07_RS00645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CpPA07_RS00645	COG2190	(PTS) system
CpPA07_RS00645	COG1263	PTS System
CpPA07_RS00670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CpPA07_RS00685	COG0287	Prephenate dehydrogenase
CpPA07_RS00705	COG2409	Drug exporters of the RND superfamily
CpPA07_RS00710	COG0343	queuine tRNA-ribosyltransferase activity
CpPA07_RS00720	COG2610	gluconate transmembrane transporter activity
CpPA07_RS00725	COG3265	gluconokinase activity
CpPA07_RS00730	COG1063	alcohol dehydrogenase
CpPA07_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
CpPA07_RS00750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CpPA07_RS00775	COG2610	gluconate transmembrane transporter activity
CpPA07_RS00780	COG2084	Dehydrogenase
CpPA07_RS00795	COG0179	Fumarylacetoacetate (FAA) hydrolase
CpPA07_RS00805	COG3442	glutamine amidotransferase
CpPA07_RS00810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CpPA07_RS00820	COG0778	Nitroreductase
CpPA07_RS00825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CpPA07_RS00830	COG2390	Transcriptional regulator
CpPA07_RS00835	COG0813	purine-nucleoside phosphorylase activity
CpPA07_RS00850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CpPA07_RS00875	COG0697	spore germination
CpPA07_RS00880	COG0527	aspartate kinase activity
CpPA07_RS00940	COG1840	ABC-type Fe3 transport system, periplasmic component
CpPA07_RS00975	COG0651	ATP synthesis coupled electron transport
CpPA07_RS00985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CpPA07_RS00985	COG2111	Na H antiporter
CpPA07_RS01005	COG4152	abc transporter atp-binding protein
CpPA07_RS01035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CpPA07_RS01060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CpPA07_RS01080	COG0494	nUDIX hydrolase
CpPA07_RS01150	COG1205	dead DEAH box helicase
CpPA07_RS01150	COG1111	helicase
CpPA07_RS01160	COG1754	DNA topoisomerase type I activity
CpPA07_RS01160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CpPA07_RS01165	COG1297	OPT oligopeptide transporter protein
CpPA07_RS01175	COG0470	DNA polymerase III
CpPA07_RS01190	COG0318	PFAM AMP-dependent synthetase and ligase
CpPA07_RS01200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CpPA07_RS01210	COG1088	dTDP-glucose 4,6-dehydratase activity
CpPA07_RS01220	COG1505	serine-type exopeptidase activity
CpPA07_RS01235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CpPA07_RS01240	COG1396	sequence-specific DNA binding
CpPA07_RS01240	COG3800	Transcriptional regulator
CpPA07_RS01250	COG1053	succinate dehydrogenase
CpPA07_RS01255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CpPA07_RS01265	COG2733	membrane
CpPA07_RS01275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CpPA07_RS01295	COG1882	Formate acetyltransferase
CpPA07_RS01315	COG0318	PFAM AMP-dependent synthetase and ligase
CpPA07_RS01330	COG5002	protein histidine kinase activity
CpPA07_RS01335	COG0745	RESPONSE REGULATOR receiver
CpPA07_RS01355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CpPA07_RS01375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CpPA07_RS01375	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CpPA07_RS01405	COG1648	precorrin-2 dehydrogenase activity
CpPA07_RS01405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CpPA07_RS01420	COG2217	Heavy metal translocating P-type atpase
CpPA07_RS01430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CpPA07_RS01445	COG0406	alpha-ribazole phosphatase activity
CpPA07_RS01455	COG0785	Cytochrome C biogenesis protein
CpPA07_RS01465	COG0275	rRNA processing
CpPA07_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS01485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CpPA07_RS01515	COG3069	C4-dicarboxylate transmembrane transporter activity
CpPA07_RS01520	COG4948	Mandelate Racemase Muconate Lactonizing
CpPA07_RS01545	COG0039	L-malate dehydrogenase activity
CpPA07_RS01550	COG0644	oxidoreductase
CpPA07_RS01555	COG0142	geranyltranstransferase activity
CpPA07_RS01580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CpPA07_RS01610	COG1902	pentaerythritol trinitrate reductase activity
CpPA07_RS01630	COG0803	Belongs to the bacterial solute-binding protein 9 family
CpPA07_RS01640	COG1121	(ABC) transporter
CpPA07_RS01645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpPA07_RS01675	COG2197	response regulator
CpPA07_RS01685	COG1131	(ABC) transporter
CpPA07_RS01700	COG0701	Predicted permease
CpPA07_RS01770	COG1302	Protein conserved in bacteria
CpPA07_RS01870	COG0814	amino acid
CpPA07_RS01875	COG1760	l-serine dehydratase
CpPA07_RS01880	COG0252	asparaginase activity
CpPA07_RS01885	COG0671	phosphoesterase, PA-phosphatase related
CpPA07_RS01935	COG1175	transmembrane transport
CpPA07_RS01940	COG3833	ABC-type maltose transport systems, permease component
CpPA07_RS01960	COG3842	ATPase activity
CpPA07_RS01965	COG0201	protein transport
CpPA07_RS02020	COG0203	ribosomal protein L17
CpPA07_RS02040	COG1404	Belongs to the peptidase S8 family
CpPA07_RS02110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CpPA07_RS02180	COG0516	GMP reductase activity
CpPA07_RS02225	COG2011	ABC-type metal ion transport system permease component
CpPA07_RS02235	COG1464	Belongs to the NlpA lipoprotein family
CpPA07_RS02240	COG1464	Belongs to the NlpA lipoprotein family
CpPA07_RS02260	COG0803	Belongs to the bacterial solute-binding protein 9 family
CpPA07_RS02265	COG1121	(ABC) transporter
CpPA07_RS02275	COG1321	iron dependent repressor
CpPA07_RS02275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CpPA07_RS02280	COG1321	iron dependent repressor
CpPA07_RS02285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CpPA07_RS02290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CpPA07_RS02325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS02330	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CpPA07_RS02345	COG2838	Isocitrate dehydrogenase
CpPA07_RS02350	COG2814	Major facilitator Superfamily
CpPA07_RS02355	COG4978	Transcriptional regulator
CpPA07_RS02355	COG0789	Transcriptional regulator
CpPA07_RS02370	COG0180	Tryptophanyl-tRNA synthetase
CpPA07_RS02375	COG1295	ribonuclease BN
CpPA07_RS02380	COG1686	Belongs to the peptidase S11 family
CpPA07_RS02415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CpPA07_RS02420	COG1473	amidohydrolase
CpPA07_RS02420	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CpPA07_RS02445	COG4770	biotin carboxylase activity
CpPA07_RS02450	COG2897	thiosulfate sulfurtransferase activity
CpPA07_RS02455	COG0189	ligase activity
CpPA07_RS02460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CpPA07_RS02460	COG2755	lipolytic protein G-D-S-L family
CpPA07_RS02470	COG0424	maF-like protein
CpPA07_RS02475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CpPA07_RS02480	COG1609	Transcriptional regulator
CpPA07_RS02490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CpPA07_RS02495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CpPA07_RS02500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CpPA07_RS02500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CpPA07_RS02550	COG1316	TRANSCRIPTIONal
CpPA07_RS02560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CpPA07_RS02595	COG1482	cell wall glycoprotein biosynthetic process
CpPA07_RS02620	COG0745	RESPONSE REGULATOR receiver
CpPA07_RS02625	COG5002	protein histidine kinase activity
CpPA07_RS02640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CpPA07_RS02680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CpPA07_RS02685	COG2135	peptidase activity
CpPA07_RS02690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CpPA07_RS02730	COG0513	Belongs to the DEAD box helicase family
CpPA07_RS02755	COG0210	DNA helicase
CpPA07_RS02765	COG2816	NAD+ diphosphatase activity
CpPA07_RS02790	COG3480	Lon protease (S16) C-terminal proteolytic domain
CpPA07_RS02915	COG0483	inositol monophosphate 1-phosphatase activity
CpPA07_RS02920	COG0483	inositol monophosphate 1-phosphatase activity
CpPA07_RS02935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CpPA07_RS02945	COG2884	Cell division ATP-binding protein ftsE
CpPA07_RS02950	COG2177	Part of the ABC transporter FtsEX involved in
CpPA07_RS02965	COG0288	reversible hydration of carbon dioxide
CpPA07_RS03025	COG1061	Type III restriction enzyme res subunit
CpPA07_RS03035	COG1652	LysM domain
CpPA07_RS03060	COG2252	PERMEase
CpPA07_RS03065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CpPA07_RS03085	COG0372	Belongs to the citrate synthase family
CpPA07_RS03090	COG0545	Peptidyl-prolyl cis-trans isomerase
CpPA07_RS03105	COG0656	L-ascorbic acid biosynthetic process
CpPA07_RS03110	COG1024	Enoyl-CoA hydratase
CpPA07_RS03120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CpPA07_RS03130	COG3757	hydrolase, family 25
CpPA07_RS03145	COG0534	Mate efflux family protein
CpPA07_RS03150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CpPA07_RS03155	COG0019	diaminopimelate decarboxylase activity
CpPA07_RS03170	COG4166	transmembrane transport
CpPA07_RS03175	COG0601	transmembrane transport
CpPA07_RS03185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CpPA07_RS03210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CpPA07_RS03225	COG1218	3'(2'),5'-bisphosphate nucleotidase
CpPA07_RS03235	COG1201	RNA secondary structure unwinding
CpPA07_RS03245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CpPA07_RS03295	COG1126	abc transporter atp-binding protein
CpPA07_RS03300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CpPA07_RS03305	COG0765	amino acid transport
CpPA07_RS03310	COG0765	amino acid transport
CpPA07_RS03320	COG1309	transcriptional regulator
CpPA07_RS03350	COG0254	rRNA binding
CpPA07_RS03360	COG0745	RESPONSE REGULATOR receiver
CpPA07_RS03365	COG2205	protein histidine kinase activity
CpPA07_RS03370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CpPA07_RS03375	COG0521	Mo-molybdopterin cofactor biosynthetic process
CpPA07_RS03375	COG0315	cyclic pyranopterin monophosphate synthase activity
CpPA07_RS03400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CpPA07_RS03420	COG2259	Doxx family
CpPA07_RS03430	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CpPA07_RS03440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CpPA07_RS03445	COG3949	Membrane
CpPA07_RS03460	COG0084	hydrolase, TatD family'
CpPA07_RS03465	COG3583	domain protein
CpPA07_RS03480	COG0488	(ABC) transporter
CpPA07_RS03495	COG2326	polyphosphate kinase activity
CpPA07_RS03540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CpPA07_RS03550	COG0193	aminoacyl-tRNA hydrolase activity
CpPA07_RS03575	COG1523	belongs to the glycosyl hydrolase 13 family
CpPA07_RS03585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CpPA07_RS03590	COG2132	Multicopper oxidase
CpPA07_RS03605	COG1309	transcriptional regulator
CpPA07_RS03615	COG0531	amino acid
CpPA07_RS03620	COG3956	TIGRFAM MazG family protein
CpPA07_RS03685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CpPA07_RS03755	COG0114	fumarate hydratase activity
CpPA07_RS03760	COG1494	fructose-1,6-bisphosphatase
CpPA07_RS03795	COG0012	GTP binding
CpPA07_RS03810	COG2824	Alkylphosphonate utilization operon protein PhnA
CpPA07_RS03815	COG1132	(ABC) transporter
CpPA07_RS03825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CpPA07_RS03830	COG2354	Protein conserved in bacteria
CpPA07_RS03840	COG4721	ABC-type cobalt transport system, permease component
CpPA07_RS03845	COG1122	ATPase activity
CpPA07_RS03855	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CpPA07_RS03865	COG4166	transmembrane transport
CpPA07_RS03870	COG0601	transmembrane transport
CpPA07_RS03875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CpPA07_RS03905	COG1217	gtp-binding protein TYPA
CpPA07_RS03910	COG4166	transmembrane transport
CpPA07_RS03945	COG1113	amino acid transport
CpPA07_RS03955	COG1113	amino acid transport
CpPA07_RS03965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CpPA07_RS03970	COG1611	Belongs to the LOG family
CpPA07_RS03975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CpPA07_RS03980	COG0463	Glycosyl transferase, family 2
CpPA07_RS04010	COG0297	glycogen (starch) synthase activity
CpPA07_RS04020	COG4122	O-methyltransferase activity
CpPA07_RS04050	COG2239	Acts as a magnesium transporter
CpPA07_RS04060	COG0508	dehydrogenase complex catalyzes the overall conversion of
CpPA07_RS04060	COG0567	Dehydrogenase, E1 component
CpPA07_RS04065	COG1132	(ABC) transporter
CpPA07_RS04075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CpPA07_RS04080	COG2272	Belongs to the type-B carboxylesterase lipase family
CpPA07_RS04100	COG2017	converts alpha-aldose to the beta-anomer
CpPA07_RS04120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CpPA07_RS04150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CpPA07_RS04155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CpPA07_RS04210	COG1556	Lactate utilization protein
CpPA07_RS04215	COG1139	Iron-sulfur cluster binding protein
CpPA07_RS04220	COG0247	lactate metabolic process
CpPA07_RS04225	COG1620	l-lactate permease
CpPA07_RS04235	COG0019	diaminopimelate decarboxylase activity
CpPA07_RS04240	COG0460	homoserine dehydrogenase
CpPA07_RS04290	COG0356	it plays a direct role in the translocation of protons across the membrane
CpPA07_RS04295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CpPA07_RS04300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CpPA07_RS04345	COG0346	lactoylglutathione lyase activity
CpPA07_RS04370	COG1119	ATPase activity
CpPA07_RS04390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CpPA07_RS04455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS04460	COG1120	ATPase activity
CpPA07_RS04470	COG0205	6-phosphofructokinase activity
CpPA07_RS04480	COG0667	Aldo Keto reductase
CpPA07_RS04490	COG0583	DNA-binding transcription factor activity
CpPA07_RS04515	COG0668	transmembrane transport
CpPA07_RS04555	COG0473	3-isopropylmalate dehydrogenase activity
CpPA07_RS04575	COG0179	Fumarylacetoacetate (FAA) hydrolase
CpPA07_RS04605	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CpPA07_RS04660	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CpPA07_RS04665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CpPA07_RS04670	COG1461	Dihydroxyacetone kinase
CpPA07_RS04680	COG0511	ligase activity, forming carbon-carbon bonds
CpPA07_RS04685	COG0742	ribosomal rna small subunit methyltransferase
CpPA07_RS04710	COG0765	amino acid transport
CpPA07_RS04735	COG2226	methyltransferase
CpPA07_RS04740	COG0539	negative regulation of cytoplasmic translation
CpPA07_RS04750	COG0237	dephospho-CoA kinase activity
CpPA07_RS04770	COG3973	AAA domain
CpPA07_RS04780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CpPA07_RS04795	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CpPA07_RS04810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CpPA07_RS04825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CpPA07_RS04840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CpPA07_RS04860	COG0165	Argininosuccinate lyase
CpPA07_RS04865	COG2835	tetraacyldisaccharide 4'-kinase activity
CpPA07_RS04900	COG0647	UMP catabolic process
CpPA07_RS04915	COG0497	DNA recombination
CpPA07_RS04930	COG0494	nUDIX hydrolase
CpPA07_RS04935	COG4974	Belongs to the 'phage' integrase family
CpPA07_RS04955	COG3104	oligopeptide transport
CpPA07_RS04960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CpPA07_RS04970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CpPA07_RS04985	COG1160	GTP binding
CpPA07_RS05000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CpPA07_RS05005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CpPA07_RS05010	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CpPA07_RS05015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS05020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS05025	COG1120	ATPase activity
CpPA07_RS05030	COG4264	IucA IucC family
CpPA07_RS05040	COG3547	Transposase (IS116 IS110 IS902 family)
CpPA07_RS05065	COG3012	SEC-C Motif Domain Protein
CpPA07_RS05075	COG0653	protein targeting
CpPA07_RS05115	COG1253	flavin adenine dinucleotide binding
CpPA07_RS05120	COG0513	Belongs to the DEAD box helicase family
CpPA07_RS05125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CpPA07_RS05135	COG0598	Magnesium transport protein CorA
CpPA07_RS05155	COG0477	Major facilitator Superfamily
CpPA07_RS05185	COG0463	Glycosyl transferase, family 2
CpPA07_RS05235	COG0300	oxidoreductase activity
CpPA07_RS05250	COG0805	protein transport
CpPA07_RS05260	COG2378	regulation of single-species biofilm formation
CpPA07_RS05280	COG4122	O-methyltransferase activity
CpPA07_RS05295	COG1362	aminopeptidase activity
CpPA07_RS05315	COG1027	Aspartate ammonia-lyase
CpPA07_RS05320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CpPA07_RS05340	COG1410	methionine synthase
CpPA07_RS05340	COG0646	methionine synthase
CpPA07_RS05360	COG0667	Aldo Keto reductase
CpPA07_RS05370	COG0167	dihydroorotate dehydrogenase activity
CpPA07_RS05395	COG1461	Dihydroxyacetone kinase
CpPA07_RS05400	COG2376	Dihydroxyacetone kinase
CpPA07_RS05410	COG3842	ATPase activity
CpPA07_RS05415	COG0488	(ABC) transporter
CpPA07_RS05480	COG3883	PFAM NLP P60 protein
CpPA07_RS05480	COG0791	NLP P60 protein
CpPA07_RS05510	COG2848	UPF0210 protein
CpPA07_RS05530	COG0488	(ABC) transporter
CpPA07_RS05535	COG2151	metal-sulfur cluster biosynthetic enzyme
CpPA07_RS05540	COG0822	iron-sulfur transferase activity
CpPA07_RS05550	COG0396	ATPase activity
CpPA07_RS05595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CpPA07_RS05600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CpPA07_RS05620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CpPA07_RS05640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CpPA07_RS05650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CpPA07_RS05660	COG0322	excinuclease ABC activity
CpPA07_RS05690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CpPA07_RS05705	COG0242	peptide deformylase activity
CpPA07_RS05745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CpPA07_RS05755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CpPA07_RS05770	COG1090	epimerase
CpPA07_RS05795	COG0006	proline dipeptidase activity
CpPA07_RS05800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CpPA07_RS05805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CpPA07_RS05810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CpPA07_RS05815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CpPA07_RS05835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CpPA07_RS05890	COG1760	l-serine dehydratase
CpPA07_RS05915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CpPA07_RS05920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CpPA07_RS05935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CpPA07_RS05950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CpPA07_RS05955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CpPA07_RS05985	COG1946	Acyl-CoA thioesterase
CpPA07_RS06000	COG0156	8-amino-7-oxononanoate synthase activity
CpPA07_RS06015	COG1560	Kdo2-lipid A biosynthetic process
CpPA07_RS06020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CpPA07_RS06035	COG2837	iron assimilation
CpPA07_RS06090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CpPA07_RS06095	COG3253	May function as heme-dependent peroxidase
CpPA07_RS06180	COG2890	protein-(glutamine-N5) methyltransferase activity
CpPA07_RS06220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CpPA07_RS06225	COG0450	alkyl hydroperoxide reductase
CpPA07_RS06240	COG1643	Atp-dependent helicase
CpPA07_RS06260	COG1349	DNA-binding transcription factor activity
CpPA07_RS06265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CpPA07_RS06270	COG1349	DNA-binding transcription factor activity
CpPA07_RS06275	COG1105	Belongs to the carbohydrate kinase PfkB family
CpPA07_RS06280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpPA07_RS06280	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CpPA07_RS06280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpPA07_RS06290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CpPA07_RS06295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CpPA07_RS06305	COG2233	PERMEase
CpPA07_RS06310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CpPA07_RS06325	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CpPA07_RS06340	COG1196	nuclear chromosome segregation
CpPA07_RS06360	COG2137	regulation of response to DNA damage stimulus
CpPA07_RS06365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CpPA07_RS06375	COG1268	BioY protein
CpPA07_RS06380	COG1122	ATPase activity
CpPA07_RS06390	COG1842	Phage shock protein A
CpPA07_RS06395	COG1396	sequence-specific DNA binding
CpPA07_RS06420	COG1674	ftsk spoiiie
CpPA07_RS06430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CpPA07_RS06470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CpPA07_RS06480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CpPA07_RS06485	COG0534	Mate efflux family protein
CpPA07_RS06530	COG3022	response to hydroperoxide
CpPA07_RS06535	COG1648	precorrin-2 dehydrogenase activity
CpPA07_RS06535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CpPA07_RS06545	COG0523	cobalamin synthesis protein
CpPA07_RS06550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CpPA07_RS06550	COG2169	Transcriptional regulator
CpPA07_RS06615	COG0750	zinc metalloprotease
CpPA07_RS06675	COG4974	Belongs to the 'phage' integrase family
CpPA07_RS06700	COG0681	Belongs to the peptidase S26 family
CpPA07_RS06715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpPA07_RS06715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CpPA07_RS06715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CpPA07_RS06725	COG0336	Belongs to the RNA methyltransferase TrmD family
CpPA07_RS06730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CpPA07_RS06750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CpPA07_RS06780	COG1115	amino acid carrier protein
CpPA07_RS06785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CpPA07_RS06810	COG0686	Belongs to the AlaDH PNT family
CpPA07_RS06815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CpPA07_RS06820	COG1929	Belongs to the glycerate kinase type-1 family
CpPA07_RS06845	COG0058	SHG alpha-glucan phosphorylase activity
CpPA07_RS06855	COG0469	pyruvate kinase activity
CpPA07_RS06865	COG0134	indole-3-glycerol-phosphate synthase activity
CpPA07_RS06885	COG0483	inositol monophosphate 1-phosphatase activity
CpPA07_RS06950	COG2176	DNA-directed DNA polymerase activity
CpPA07_RS06975	COG1739	Uncharacterized protein family UPF0029
CpPA07_RS06980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CpPA07_RS07005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CpPA07_RS07020	COG0252	asparaginase activity
CpPA07_RS07040	COG3599	regulation of cell shape
CpPA07_RS07050	COG1799	cell septum assembly
CpPA07_RS07060	COG1496	oxidoreductase activity
CpPA07_RS07065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CpPA07_RS07075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CpPA07_RS07105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CpPA07_RS07110	COG0768	penicillin binding
CpPA07_RS07155	COG0142	geranyltranstransferase activity
CpPA07_RS07170	COG2815	serine threonine protein kinase
CpPA07_RS07170	COG0515	serine threonine protein kinase
CpPA07_RS07175	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CpPA07_RS07195	COG1940	carbohydrate kinase activity
CpPA07_RS07200	COG0438	transferase activity, transferring glycosyl groups
CpPA07_RS07210	COG0791	NLP P60 protein
CpPA07_RS07260	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CpPA07_RS07265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CpPA07_RS07275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CpPA07_RS07290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CpPA07_RS07295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CpPA07_RS07295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CpPA07_RS07300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CpPA07_RS07305	COG0509	glycine decarboxylation via glycine cleavage system
CpPA07_RS07335	COG0174	glutamine synthetase
CpPA07_RS07480	COG2056	Na+-H+ antiporter family
CpPA07_RS07490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CpPA07_RS07515	COG0174	glutamine synthetase
CpPA07_RS07540	COG0557	exoribonuclease II activity
CpPA07_RS07560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CpPA07_RS07560	COG3323	Protein of unknown function (DUF1653)
CpPA07_RS07600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CpPA07_RS07605	COG0596	Alpha beta hydrolase
CpPA07_RS07630	COG2860	membrane
CpPA07_RS07700	COG0423	glycine-tRNA ligase activity
CpPA07_RS07730	COG1381	Involved in DNA repair and RecF pathway recombination
CpPA07_RS07785	COG1022	Amp-dependent synthetase and ligase
CpPA07_RS07835	COG1132	(ABC) transporter
CpPA07_RS07840	COG1114	Component of the transport system for branched-chain amino acids
CpPA07_RS07845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CpPA07_RS07855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CpPA07_RS07870	COG0747	negative chemotaxis
CpPA07_RS07875	COG0601	transmembrane transport
CpPA07_RS07880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CpPA07_RS07885	COG4172	Belongs to the ABC transporter superfamily
CpPA07_RS07895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CpPA07_RS07900	COG2391	methyltransferase activity
CpPA07_RS07910	COG4171	peptide transport system, permease
CpPA07_RS07925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CpPA07_RS07930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CpPA07_RS07955	COG1280	lysine exporter protein (LysE YggA)
CpPA07_RS07980	COG1307	EDD domain protein, DegV family
CpPA07_RS07985	COG0406	alpha-ribazole phosphatase activity
CpPA07_RS07995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CpPA07_RS08010	COG2832	Protein of unknown function (DUF454)
CpPA07_RS08015	COG2985	domain, Protein
CpPA07_RS08015	COG0569	domain protein
CpPA07_RS08040	COG1530	ribonuclease E activity
CpPA07_RS08055	COG2423	ornithine cyclodeaminase activity
CpPA07_RS08065	COG0285	dihydrofolate synthase activity
CpPA07_RS08105	COG0544	peptidyl-prolyl cis-trans isomerase activity
CpPA07_RS08140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CpPA07_RS08150	COG0668	transmembrane transport
CpPA07_RS08230	COG1131	(ABC) transporter
CpPA07_RS08235	COG3336	cytochrome c oxidase
CpPA07_RS08240	COG1966	Carbon starvation protein
CpPA07_RS08260	COG0604	alcohol dehydrogenase
CpPA07_RS08285	COG1376	ErfK ybiS ycfS ynhG family protein
CpPA07_RS08295	COG2130	NADP-dependent
CpPA07_RS08300	COG1335	isochorismatase
CpPA07_RS08345	COG2197	response regulator
CpPA07_RS08395	COG1234	tRNA 3'-trailer cleavage
CpPA07_RS08420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CpPA07_RS08465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CpPA07_RS08475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CpPA07_RS08495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CpPA07_RS08565	COG0033	Phosphoglucomutase
CpPA07_RS08580	COG0577	efflux transmembrane transporter activity
CpPA07_RS08580	COG1136	(ABC) transporter
CpPA07_RS08585	COG0577	efflux transmembrane transporter activity
CpPA07_RS08585	COG1136	(ABC) transporter
CpPA07_RS08620	COG2197	response regulator
CpPA07_RS08635	COG1045	serine acetyltransferase
CpPA07_RS08655	COG0371	Dehydrogenase
CpPA07_RS08675	COG1271	oxidase subunit
CpPA07_RS08680	COG1294	oxidase, subunit
CpPA07_RS08685	COG4988	ABC transporter
CpPA07_RS08690	COG1132	(ABC) transporter
CpPA07_RS08715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CpPA07_RS08745	COG1597	lipid kinase activity
CpPA07_RS08760	COG0354	folic acid binding
CpPA07_RS08785	COG1780	Probably involved in ribonucleotide reductase function
CpPA07_RS08790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CpPA07_RS08800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CpPA07_RS08805	COG0047	phosphoribosylformylglycinamidine synthase activity
CpPA07_RS08810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CpPA07_RS08815	COG0386	Belongs to the glutathione peroxidase family
CpPA07_RS08835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CpPA07_RS08840	COG0569	domain protein
CpPA07_RS08845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CpPA07_RS08850	COG0151	Belongs to the GarS family
CpPA07_RS08855	COG0537	adenosine 5'-monophosphoramidase activity
CpPA07_RS08865	COG2205	protein histidine kinase activity
CpPA07_RS08870	COG0745	RESPONSE REGULATOR receiver
CpPA07_RS08900	COG0028	Belongs to the TPP enzyme family
CpPA07_RS08950	COG1609	Transcriptional regulator
CpPA07_RS08960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CpPA07_RS08980	COG1329	Transcriptional regulator
CpPA07_RS08985	COG2847	Copper chaperone PCu(A)C
CpPA07_RS09000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CpPA07_RS09010	COG0288	reversible hydration of carbon dioxide
CpPA07_RS09040	COG0477	Major facilitator Superfamily
CpPA07_RS09045	COG1957	nucleoside hydrolase
CpPA07_RS09060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CpPA07_RS09075	COG1301	dicarboxylic acid transport
CpPA07_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
CpPA07_RS09085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CpPA07_RS09090	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CpPA07_RS09095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CpPA07_RS09125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CpPA07_RS09130	COG0302	gtp cyclohydrolase
CpPA07_RS09135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CpPA07_RS09140	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CpPA07_RS09150	COG2027	D-alanyl-D-alanine carboxypeptidase
CpPA07_RS09155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CpPA07_RS09160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CpPA07_RS09160	COG0425	Belongs to the sulfur carrier protein TusA family
CpPA07_RS09165	COG1301	dicarboxylic acid transport
CpPA07_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CpPA07_RS09190	COG2326	polyphosphate kinase activity
CpPA07_RS09235	COG2111	Na H antiporter
CpPA07_RS09235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CpPA07_RS09240	COG1006	Multisubunit Na H antiporter MnhC subunit
CpPA07_RS09245	COG0651	ATP synthesis coupled electron transport
CpPA07_RS09265	COG1051	belongs to the nudix hydrolase family
CpPA07_RS09285	COG0242	peptide deformylase activity
CpPA07_RS09290	COG0456	acetyltransferase
CpPA07_RS09300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CpPA07_RS09325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CpPA07_RS09340	COG0280	phosphate acetyltransferase
CpPA07_RS09360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CpPA07_RS09365	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CpPA07_RS09395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CpPA07_RS09400	COG1333	cytochrome c biogenesis protein
CpPA07_RS09410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CpPA07_RS09415	COG3005	denitrification pathway
CpPA07_RS09430	COG4129	membrane
CpPA07_RS09440	COG4129	membrane
CpPA07_RS09475	COG0191	fructose-bisphosphate aldolase activity
CpPA07_RS09490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CpPA07_RS09505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CpPA07_RS09545	COG1131	(ABC) transporter
CpPA07_RS09595	COG0577	efflux transmembrane transporter activity
CpPA07_RS09595	COG1136	(ABC) transporter
CpPA07_RS09600	COG1136	(ABC) transporter
CpPA07_RS09605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CpPA07_RS09645	COG0789	Transcriptional regulator
CpPA07_RS09660	COG0443	Heat shock 70 kDa protein
CpPA07_RS09715	COG0247	lactate metabolic process
CpPA07_RS09715	COG2181	nitrate reductase activity
CpPA07_RS09730	COG1120	ATPase activity
CpPA07_RS09735	COG4139	cobalamin transport
CpPA07_RS09745	COG0829	nickel cation binding
CpPA07_RS09750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CpPA07_RS09760	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CpPA07_RS09765	COG0804	urea catabolic process
CpPA07_RS09770	COG0832	Belongs to the urease beta subunit family
CpPA07_RS09775	COG0831	urea catabolic process
CpPA07_RS09800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CpPA07_RS09800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CpPA07_RS09815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CpPA07_RS09830	COG1012	belongs to the aldehyde dehydrogenase family
CpPA07_RS09840	COG1472	Belongs to the glycosyl hydrolase 3 family
CpPA07_RS09850	COG4981	capsule polysaccharide biosynthetic process
CpPA07_RS09855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CpPA07_RS09855	COG2755	lipolytic protein G-D-S-L family
CpPA07_RS09870	COG0438	transferase activity, transferring glycosyl groups
CpPA07_RS09875	COG0500	methyltransferase
CpPA07_RS09920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CpPA07_RS09925	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CpPA07_RS09925	COG3321	synthase
CpPA07_RS09925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CpPA07_RS09930	COG0318	PFAM AMP-dependent synthetase and ligase
CpPA07_RS09935	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CpPA07_RS09945	COG5479	isomerase activity
CpPA07_RS09945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CpPA07_RS09960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CpPA07_RS09965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CpPA07_RS09970	COG0671	phosphoesterase, PA-phosphatase related
CpPA07_RS09975	COG1216	Glycosyl transferase, family 2
CpPA07_RS09985	COG0671	phosphoesterase, PA-phosphatase related
CpPA07_RS09995	COG0584	glycerophosphoryl diester phosphodiesterase
CpPA07_RS10000	COG2271	Major facilitator Superfamily
CpPA07_RS10015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CpPA07_RS10020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CpPA07_RS10030	COG0561	phosphatase activity
CpPA07_RS10045	COG2188	Transcriptional regulator
CpPA07_RS10070	COG0154	amidase activity
CpPA07_RS10080	COG1316	TRANSCRIPTIONal
CpPA07_RS10110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CpPA07_RS10140	COG0431	NADPH-dependent FMN reductase
CpPA07_RS10145	COG2814	Major facilitator Superfamily
CpPA07_RS10165	COG2271	Major facilitator Superfamily
CpPA07_RS10180	COG5650	phosphatidylinositol metabolic process
CpPA07_RS10200	COG2197	response regulator
CpPA07_RS10220	COG3764	Sortase (surface protein transpeptidase)
CpPA07_RS10225	COG0706	membrane insertase activity
CpPA07_RS10250	COG0564	pseudouridine synthase activity
CpPA07_RS10280	COG1131	(ABC) transporter
CpPA07_RS10295	COG1842	Phage shock protein A
CpPA07_RS10300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CpPA07_RS10315	COG0477	Major facilitator Superfamily
CpPA07_RS10320	COG0305	Participates in initiation and elongation during chromosome replication
CpPA07_RS10325	COG3387	PFAM Glycoside hydrolase 15-related
CpPA07_RS10340	COG0629	single-stranded DNA binding
CpPA07_RS10365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CpPA07_RS10385	COG0300	oxidoreductase activity
CpPA07_RS10400	COG0586	Pfam SNARE associated Golgi protein
CpPA07_RS10405	COG0783	Belongs to the Dps family
CpPA07_RS10410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CpPA07_RS10415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CpPA07_RS10415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CpPA07_RS10425	COG1511	domain protein
CpPA07_RS10435	COG0577	efflux transmembrane transporter activity
CpPA07_RS10435	COG1136	(ABC) transporter
CpPA07_RS10455	COG4585	Histidine kinase
CpPA07_RS10460	COG2197	response regulator
CpPA07_RS10475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CpPA07_RS10490	COG2186	Transcriptional regulator
CpPA07_RS10495	COG0747	negative chemotaxis
CpPA07_RS10500	COG0601	transmembrane transport
CpPA07_RS10505	COG0444	Belongs to the ABC transporter superfamily
CpPA07_RS10510	COG4608	Belongs to the ABC transporter superfamily
CpPA07_RS10515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CpPA07_RS10555	COG3422	double-strand break repair
CpPA07_RS10570	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CpPA07_RS10590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CpPA07_RS10595	COG0512	Glutamine amidotransferase of anthranilate synthase
CpPA07_RS10605	COG0135	phosphoribosylanthranilate isomerase activity
CpPA07_RS10605	COG0134	indole-3-glycerol-phosphate synthase activity
CpPA07_RS10640	COG1687	branched-chain amino acid
CpPA07_RS10645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CpPA07_RS10650	COG1678	Uncharacterized ACR, COG1678
CpPA07_RS10655	COG0617	tRNA 3'-terminal CCA addition
CpPA07_RS10690	COG3409	Peptidoglycan-binding domain 1 protein
CpPA07_RS10690	COG0860	N-Acetylmuramoyl-L-alanine amidase
CpPA07_RS10705	COG1192	Involved in chromosome partitioning
CpPA07_RS10720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CpPA07_RS10730	COG0230	Belongs to the bacterial ribosomal protein bL34 family