locus-tag	class	description
ccrud_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ccrud_RS00015	COG0592	DNA-directed DNA polymerase activity
ccrud_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ccrud_RS00030	COG0187	DNA topoisomerase II activity
ccrud_RS00090	COG0583	DNA-binding transcription factor activity
ccrud_RS00095	COG0737	Belongs to the 5'-nucleotidase family
ccrud_RS00095	COG1525	nuclease
ccrud_RS00095	COG4085	toxin activity
ccrud_RS00120	COG1172	Belongs to the binding-protein-dependent transport system permease family
ccrud_RS00135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ccrud_RS00150	COG2815	serine threonine protein kinase
ccrud_RS00150	COG0515	serine threonine protein kinase
ccrud_RS00155	COG0515	serine threonine protein kinase
ccrud_RS00160	COG0768	penicillin binding
ccrud_RS00180	COG1716	ATPase activity
ccrud_RS00195	COG1053	succinate dehydrogenase
ccrud_RS00200	COG0477	Major facilitator Superfamily
ccrud_RS00210	COG1053	succinate dehydrogenase
ccrud_RS00275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ccrud_RS00280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ccrud_RS00285	COG1937	Protein conserved in bacteria
ccrud_RS00330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ccrud_RS00340	COG2851	Citrate transporter
ccrud_RS00345	COG3290	protein histidine kinase activity
ccrud_RS00350	COG4565	transcriptional regulatory protein
ccrud_RS00355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ccrud_RS00365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ccrud_RS00390	COG2226	methyltransferase
ccrud_RS00415	COG0477	Major facilitator Superfamily
ccrud_RS00420	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS00430	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS00460	COG2610	gluconate transmembrane transporter activity
ccrud_RS00500	COG0804	urea catabolic process
ccrud_RS00510	COG0830	nickel cation binding
ccrud_RS00515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ccrud_RS00545	COG0326	Molecular chaperone. Has ATPase activity
ccrud_RS00550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ccrud_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
ccrud_RS00565	COG0667	Aldo Keto reductase
ccrud_RS00570	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ccrud_RS00580	COG2149	membrane
ccrud_RS00595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS00600	COG0346	lactoylglutathione lyase activity
ccrud_RS00605	COG2062	phosphohistidine phosphatase, SixA
ccrud_RS00615	COG2814	Major facilitator Superfamily
ccrud_RS00625	COG1070	Carbohydrate kinase
ccrud_RS00630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ccrud_RS00640	COG3177	Filamentation induced by cAMP protein fic
ccrud_RS00650	COG1396	sequence-specific DNA binding
ccrud_RS00655	COG2094	Belongs to the DNA glycosylase MPG family
ccrud_RS00660	COG0322	excinuclease ABC activity
ccrud_RS00675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ccrud_RS00700	COG2860	membrane
ccrud_RS00720	COG3180	Ammonia monooxygenase
ccrud_RS00730	COG0730	response to heat
ccrud_RS00740	COG1643	Atp-dependent helicase
ccrud_RS00750	COG0110	maltose O-acetyltransferase activity
ccrud_RS00765	COG1280	lysine exporter protein (LysE YggA)
ccrud_RS00795	COG0251	oxidation-reduction process
ccrud_RS00805	COG3590	peptidase
ccrud_RS00820	COG2188	Transcriptional regulator
ccrud_RS00825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ccrud_RS00840	COG3718	enzyme involved in inositol metabolism
ccrud_RS00845	COG3962	Belongs to the TPP enzyme family
ccrud_RS00860	COG1082	Xylose isomerase domain protein TIM barrel
ccrud_RS00890	COG0673	inositol 2-dehydrogenase activity
ccrud_RS00910	COG3842	ATPase activity
ccrud_RS00920	COG1609	Transcriptional regulator
ccrud_RS00930	COG2814	Major facilitator Superfamily
ccrud_RS00975	COG0069	glutamate synthase activity
ccrud_RS00975	COG0070	glutamate synthase
ccrud_RS00975	COG0067	glutamate synthase
ccrud_RS00990	COG2197	response regulator
ccrud_RS01010	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS01015	COG0277	FAD linked oxidase domain protein
ccrud_RS01055	COG1216	Glycosyl transferase, family 2
ccrud_RS01080	COG0604	alcohol dehydrogenase
ccrud_RS01100	COG1115	amino acid carrier protein
ccrud_RS01120	COG0521	Mo-molybdopterin cofactor biosynthetic process
ccrud_RS01120	COG0315	cyclic pyranopterin monophosphate synthase activity
ccrud_RS01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
ccrud_RS01150	COG3842	ATPase activity
ccrud_RS01155	COG1950	PFAM Membrane protein of
ccrud_RS01160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ccrud_RS01175	COG2239	Acts as a magnesium transporter
ccrud_RS01180	COG0471	metal ion transport
ccrud_RS01190	COG0287	Prephenate dehydrogenase
ccrud_RS01205	COG3237	CsbD-like
ccrud_RS01220	COG2409	Drug exporters of the RND superfamily
ccrud_RS01225	COG0343	queuine tRNA-ribosyltransferase activity
ccrud_RS01245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ccrud_RS01265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ccrud_RS01305	COG3442	glutamine amidotransferase
ccrud_RS01310	COG0189	ligase activity
ccrud_RS01310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ccrud_RS01340	COG0697	spore germination
ccrud_RS01345	COG0527	aspartate kinase activity
ccrud_RS01390	COG0651	ATP synthesis coupled electron transport
ccrud_RS01395	COG1006	Multisubunit Na H antiporter MnhC subunit
ccrud_RS01400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ccrud_RS01400	COG2111	Na H antiporter
ccrud_RS01410	COG0745	RESPONSE REGULATOR receiver
ccrud_RS01415	COG3850	Histidine kinase
ccrud_RS01415	COG5002	protein histidine kinase activity
ccrud_RS01445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ccrud_RS01460	COG0477	Major facilitator Superfamily
ccrud_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS01485	COG1960	acyl-CoA dehydrogenase activity
ccrud_RS01495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ccrud_RS01500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ccrud_RS01515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ccrud_RS01530	COG0596	Alpha beta hydrolase
ccrud_RS01580	COG1205	dead DEAH box helicase
ccrud_RS01580	COG1111	helicase
ccrud_RS01585	COG1278	Cold shock
ccrud_RS01595	COG1754	DNA topoisomerase type I activity
ccrud_RS01595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ccrud_RS01610	COG0470	DNA polymerase III
ccrud_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS01665	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS01700	COG0737	Belongs to the 5'-nucleotidase family
ccrud_RS01700	COG1525	nuclease
ccrud_RS01700	COG4085	toxin activity
ccrud_RS01705	COG1064	alcohol dehydrogenase
ccrud_RS01710	COG2207	Transcriptional regulator
ccrud_RS01710	COG3708	Transcriptional regulator
ccrud_RS01715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ccrud_RS01725	COG1088	dTDP-glucose 4,6-dehydratase activity
ccrud_RS01730	COG2391	methyltransferase activity
ccrud_RS01755	COG1505	serine-type exopeptidase activity
ccrud_RS01790	COG2149	membrane
ccrud_RS01805	COG2340	Cysteine-rich secretory protein family
ccrud_RS01825	COG0489	protein tyrosine kinase activity
ccrud_RS01840	COG1086	Polysaccharide biosynthesis protein
ccrud_RS01845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ccrud_RS01860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ccrud_RS01880	COG1215	transferase activity, transferring glycosyl groups
ccrud_RS01885	COG2801	Transposase and inactivated derivatives
ccrud_RS01900	COG2801	Transposase and inactivated derivatives
ccrud_RS01945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ccrud_RS01950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ccrud_RS01970	COG1396	sequence-specific DNA binding
ccrud_RS01970	COG3800	Transcriptional regulator
ccrud_RS01980	COG1053	succinate dehydrogenase
ccrud_RS01985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ccrud_RS02025	COG2733	membrane
ccrud_RS02055	COG0788	formyltetrahydrofolate deformylase activity
ccrud_RS02060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ccrud_RS02070	COG1937	Protein conserved in bacteria
ccrud_RS02105	COG0318	PFAM AMP-dependent synthetase and ligase
ccrud_RS02120	COG5002	protein histidine kinase activity
ccrud_RS02125	COG0745	RESPONSE REGULATOR receiver
ccrud_RS02135	COG0577	efflux transmembrane transporter activity
ccrud_RS02175	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ccrud_RS02200	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ccrud_RS02200	COG1082	Xylose isomerase domain protein TIM barrel
ccrud_RS02215	COG0222	ribosome binding
ccrud_RS02220	COG3842	ATPase activity
ccrud_RS02235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ccrud_RS02235	COG1648	precorrin-2 dehydrogenase activity
ccrud_RS02245	COG0113	porphobilinogen synthase activity
ccrud_RS02280	COG0406	alpha-ribazole phosphatase activity
ccrud_RS02290	COG0785	Cytochrome C biogenesis protein
ccrud_RS02295	COG1333	cytochrome c biogenesis protein
ccrud_RS02300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ccrud_RS02305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ccrud_RS02315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ccrud_RS02375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ccrud_RS02380	COG0583	DNA-binding transcription factor activity
ccrud_RS02415	COG2154	pterin-4-alpha-carbinolamine dehydratase
ccrud_RS02420	COG3340	Belongs to the peptidase S51 family
ccrud_RS02425	COG4948	Mandelate Racemase Muconate Lactonizing
ccrud_RS02440	COG0438	transferase activity, transferring glycosyl groups
ccrud_RS02440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ccrud_RS02445	COG1113	amino acid transport
ccrud_RS02460	COG0142	geranyltranstransferase activity
ccrud_RS02490	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ccrud_RS02500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ccrud_RS02525	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ccrud_RS02550	COG0085	RNA polymerase activity
ccrud_RS02555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ccrud_RS02585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ccrud_RS02630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ccrud_RS02705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ccrud_RS02730	COG3845	ABC transporter
ccrud_RS02765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ccrud_RS02775	COG1841	ribosomal large subunit assembly
ccrud_RS02810	COG3848	Pyruvate phosphate dikinase
ccrud_RS02810	COG0574	Belongs to the PEP-utilizing enzyme family
ccrud_RS02815	COG0574	Belongs to the PEP-utilizing enzyme family
ccrud_RS02815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ccrud_RS02825	COG1414	Transcriptional regulator
ccrud_RS02830	COG0201	protein transport
ccrud_RS02865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ccrud_RS02875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ccrud_RS02895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ccrud_RS02905	COG0203	ribosomal protein L17
ccrud_RS02910	COG0101	tRNA pseudouridine synthase activity
ccrud_RS02930	COG1404	Belongs to the peptidase S8 family
ccrud_RS02940	COG1674	ftsk spoiiie
ccrud_RS03000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ccrud_RS03010	COG2985	domain, Protein
ccrud_RS03010	COG0569	domain protein
ccrud_RS03025	COG0456	acetyltransferase
ccrud_RS03035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ccrud_RS03035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ccrud_RS03050	COG0459	protein refolding
ccrud_RS03080	COG0516	GMP reductase activity
ccrud_RS03105	COG2197	response regulator
ccrud_RS03165	COG2409	Drug exporters of the RND superfamily
ccrud_RS03185	COG0702	epimerase
ccrud_RS03190	COG0415	Belongs to the DNA photolyase family
ccrud_RS03205	COG1136	(ABC) transporter
ccrud_RS03205	COG0577	efflux transmembrane transporter activity
ccrud_RS03210	COG2011	ABC-type metal ion transport system permease component
ccrud_RS03215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ccrud_RS03220	COG1464	Belongs to the NlpA lipoprotein family
ccrud_RS03245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ccrud_RS03255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ccrud_RS03280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ccrud_RS03285	COG2873	o-acetylhomoserine
ccrud_RS03290	COG1966	Carbon starvation protein
ccrud_RS03300	COG2838	Isocitrate dehydrogenase
ccrud_RS03315	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ccrud_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ccrud_RS03330	COG2814	Major facilitator Superfamily
ccrud_RS03340	COG2860	membrane
ccrud_RS03355	COG1120	ATPase activity
ccrud_RS03360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ccrud_RS03365	COG0180	Tryptophanyl-tRNA synthetase
ccrud_RS03370	COG1295	ribonuclease BN
ccrud_RS03380	COG1686	Belongs to the peptidase S11 family
ccrud_RS03390	COG1388	LysM domain
ccrud_RS03390	COG0791	NLP P60 protein
ccrud_RS03410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ccrud_RS03415	COG1473	amidohydrolase
ccrud_RS03415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ccrud_RS03425	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ccrud_RS03430	COG0492	ferredoxin-NADP+ reductase activity
ccrud_RS03435	COG2079	MmgE PrpD family protein
ccrud_RS03440	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ccrud_RS03445	COG0372	Belongs to the citrate synthase family
ccrud_RS03450	COG4770	biotin carboxylase activity
ccrud_RS03455	COG2897	thiosulfate sulfurtransferase activity
ccrud_RS03460	COG0189	ligase activity
ccrud_RS03485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ccrud_RS03490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ccrud_RS03535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS03585	COG3842	ATPase activity
ccrud_RS03605	COG1316	TRANSCRIPTIONal
ccrud_RS03645	COG1482	cell wall glycoprotein biosynthetic process
ccrud_RS03670	COG0745	RESPONSE REGULATOR receiver
ccrud_RS03675	COG5002	protein histidine kinase activity
ccrud_RS03680	COG5401	PFAM Sporulation and spore germination
ccrud_RS03690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ccrud_RS03705	COG1011	Hydrolase
ccrud_RS03715	COG1162	GTPase activity
ccrud_RS03720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ccrud_RS03785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ccrud_RS03790	COG2816	NAD+ diphosphatase activity
ccrud_RS03815	COG3480	Lon protease (S16) C-terminal proteolytic domain
ccrud_RS03840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ccrud_RS03845	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ccrud_RS03865	COG2314	TM2 domain
ccrud_RS03875	COG0483	inositol monophosphate 1-phosphatase activity
ccrud_RS03880	COG0483	inositol monophosphate 1-phosphatase activity
ccrud_RS03890	COG2884	Cell division ATP-binding protein ftsE
ccrud_RS03895	COG2177	Part of the ABC transporter FtsEX involved in
ccrud_RS03905	COG3189	MarR family transcriptional regulator
ccrud_RS04020	COG1061	Type III restriction enzyme res subunit
ccrud_RS04035	COG1652	LysM domain
ccrud_RS04040	COG1278	Cold shock
ccrud_RS04060	COG2252	PERMEase
ccrud_RS04065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ccrud_RS04085	COG0372	Belongs to the citrate synthase family
ccrud_RS04090	COG0545	Peptidyl-prolyl cis-trans isomerase
ccrud_RS04105	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ccrud_RS04115	COG3757	hydrolase, family 25
ccrud_RS04120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ccrud_RS04150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ccrud_RS04165	COG1218	3'(2'),5'-bisphosphate nucleotidase
ccrud_RS04170	COG1201	RNA secondary structure unwinding
ccrud_RS04175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ccrud_RS04180	COG3304	Inner membrane component domain
ccrud_RS04185	COG0586	Pfam SNARE associated Golgi protein
ccrud_RS04195	COG2807	transmembrane transport
ccrud_RS04200	COG0166	Belongs to the GPI family
ccrud_RS04215	COG1605	Chorismate mutase
ccrud_RS04240	COG0739	heme binding
ccrud_RS04255	COG0138	bifunctional purine biosynthesis protein purh
ccrud_RS04265	COG1309	transcriptional regulator
ccrud_RS04280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ccrud_RS04295	COG0659	secondary active sulfate transmembrane transporter activity
ccrud_RS04325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ccrud_RS04340	COG1970	mechanosensitive ion channel activity
ccrud_RS04355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ccrud_RS04365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ccrud_RS04375	COG2807	transmembrane transport
ccrud_RS04390	COG0366	Alpha amylase catalytic
ccrud_RS04395	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
ccrud_RS04405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ccrud_RS04415	COG0514	ATP-dependent DNA helicase (RecQ)
ccrud_RS04430	COG4762	Protein conserved in bacteria
ccrud_RS04435	COG0698	ribose 5-phosphate isomerase
ccrud_RS04450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ccrud_RS04455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ccrud_RS04455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ccrud_RS04470	COG2084	Dehydrogenase
ccrud_RS04490	COG0084	hydrolase, TatD family'
ccrud_RS04495	COG3583	domain protein
ccrud_RS04500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ccrud_RS04510	COG0488	(ABC) transporter
ccrud_RS04535	COG2326	polyphosphate kinase activity
ccrud_RS04540	COG0561	phosphatase activity
ccrud_RS04560	COG5479	isomerase activity
ccrud_RS04560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ccrud_RS04570	COG2409	Drug exporters of the RND superfamily
ccrud_RS04575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ccrud_RS04595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ccrud_RS04615	COG1129	ABC transporter
ccrud_RS04625	COG0193	aminoacyl-tRNA hydrolase activity
ccrud_RS04645	COG0193	aminoacyl-tRNA hydrolase activity
ccrud_RS04665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ccrud_RS04670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ccrud_RS04680	COG2132	Multicopper oxidase
ccrud_RS04685	COG1131	(ABC) transporter
ccrud_RS04695	COG4585	Histidine kinase
ccrud_RS04720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ccrud_RS04735	COG0405	Gamma-glutamyltransferase
ccrud_RS04750	COG1309	transcriptional regulator
ccrud_RS04770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ccrud_RS04775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ccrud_RS04780	COG0531	amino acid
ccrud_RS04790	COG3956	TIGRFAM MazG family protein
ccrud_RS04835	COG2207	Transcriptional regulator
ccrud_RS04850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ccrud_RS04860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ccrud_RS04870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ccrud_RS04875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ccrud_RS04940	COG1914	H( )-stimulated, divalent metal cation uptake system
ccrud_RS04945	COG1802	Transcriptional regulator
ccrud_RS04955	COG0114	fumarate hydratase activity
ccrud_RS04960	COG1802	Transcriptional regulator
ccrud_RS04965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ccrud_RS04985	COG1494	fructose-1,6-bisphosphatase
ccrud_RS04995	COG2814	Major facilitator Superfamily
ccrud_RS05010	COG1570	exodeoxyribonuclease VII activity
ccrud_RS05025	COG0628	permease
ccrud_RS05035	COG0733	neurotransmitter:sodium symporter activity
ccrud_RS05040	COG0012	GTP binding
ccrud_RS05045	COG1278	Cold shock
ccrud_RS05095	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ccrud_RS05100	COG0406	alpha-ribazole phosphatase activity
ccrud_RS05115	COG0488	(ABC) transporter
ccrud_RS05125	COG2824	Alkylphosphonate utilization operon protein PhnA
ccrud_RS05135	COG2814	Major facilitator Superfamily
ccrud_RS05150	COG1104	cysteine desulfurase activity
ccrud_RS05160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ccrud_RS05180	COG2315	Protein conserved in bacteria
ccrud_RS05185	COG0095	Lipoate-protein ligase
ccrud_RS05200	COG4721	ABC-type cobalt transport system, permease component
ccrud_RS05205	COG1122	ATPase activity
ccrud_RS05220	COG0387	Pfam Sodium calcium exchanger
ccrud_RS05230	COG5522	Integral membrane protein (intg_mem_TP0381)
ccrud_RS05235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ccrud_RS05240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ccrud_RS05250	COG2354	Protein conserved in bacteria
ccrud_RS05255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ccrud_RS05265	COG0494	nUDIX hydrolase
ccrud_RS05285	COG3949	Membrane
ccrud_RS05300	COG1217	gtp-binding protein TYPA
ccrud_RS05340	COG2171	N-acyltransferase activity
ccrud_RS05345	COG1113	amino acid transport
ccrud_RS05355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ccrud_RS05360	COG1611	Belongs to the LOG family
ccrud_RS05365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ccrud_RS05370	COG0463	Glycosyl transferase, family 2
ccrud_RS05395	COG0297	glycogen (starch) synthase activity
ccrud_RS05405	COG4122	O-methyltransferase activity
ccrud_RS05410	COG1595	DNA-templated transcription, initiation
ccrud_RS05455	COG0567	Dehydrogenase, E1 component
ccrud_RS05455	COG0508	dehydrogenase complex catalyzes the overall conversion of
ccrud_RS05460	COG1132	(ABC) transporter
ccrud_RS05470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ccrud_RS05475	COG2272	Belongs to the type-B carboxylesterase lipase family
ccrud_RS05495	COG2814	Major facilitator Superfamily
ccrud_RS05530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ccrud_RS05535	COG4988	ABC transporter
ccrud_RS05540	COG1294	oxidase, subunit
ccrud_RS05545	COG1271	oxidase subunit
ccrud_RS05575	COG1454	alcohol dehydrogenase
ccrud_RS05595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ccrud_RS05600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ccrud_RS05625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ccrud_RS05645	COG2031	fatty acid transporter
ccrud_RS05650	COG2353	YceI-like domain
ccrud_RS05655	COG1846	Transcriptional regulator
ccrud_RS05670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ccrud_RS05705	COG0019	diaminopimelate decarboxylase activity
ccrud_RS05710	COG0460	homoserine dehydrogenase
ccrud_RS05735	COG1140	nitrate reductase beta subunit
ccrud_RS05750	COG0315	cyclic pyranopterin monophosphate synthase activity
ccrud_RS05750	COG0521	Mo-molybdopterin cofactor biosynthetic process
ccrud_RS05760	COG1253	flavin adenine dinucleotide binding
ccrud_RS05765	COG1253	flavin adenine dinucleotide binding
ccrud_RS05770	COG0746	molybdenum cofactor guanylyltransferase activity
ccrud_RS05820	COG0356	it plays a direct role in the translocation of protons across the membrane
ccrud_RS05825	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ccrud_RS05840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ccrud_RS05845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ccrud_RS05855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ccrud_RS05865	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ccrud_RS05870	COG0346	lactoylglutathione lyase activity
ccrud_RS05885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ccrud_RS05890	COG0366	Alpha amylase catalytic
ccrud_RS05895	COG1119	ATPase activity
ccrud_RS05915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ccrud_RS05920	COG1104	cysteine desulfurase activity
ccrud_RS05935	COG1396	sequence-specific DNA binding
ccrud_RS06000	COG0154	amidase activity
ccrud_RS06015	COG0205	6-phosphofructokinase activity
ccrud_RS06020	COG1609	Transcriptional regulator
ccrud_RS06025	COG1129	ABC transporter
ccrud_RS06030	COG1172	Belongs to the binding-protein-dependent transport system permease family
ccrud_RS06050	COG0385	Bile acid
ccrud_RS06065	COG0667	Aldo Keto reductase
ccrud_RS06070	COG1279	arginine transmembrane transporter activity
ccrud_RS06075	COG0583	DNA-binding transcription factor activity
ccrud_RS06080	COG0435	Glutathione S-transferase
ccrud_RS06095	COG0129	dihydroxy-acid dehydratase activity
ccrud_RS06105	COG0668	transmembrane transport
ccrud_RS06110	COG0028	Belongs to the TPP enzyme family
ccrud_RS06150	COG0473	3-isopropylmalate dehydrogenase activity
ccrud_RS06160	COG0517	IMP dehydrogenase activity
ccrud_RS06160	COG0516	GMP reductase activity
ccrud_RS06170	COG0179	Fumarylacetoacetate (FAA) hydrolase
ccrud_RS06190	COG3655	Transcriptional regulator
ccrud_RS06325	COG1074	ATP-dependent DNA helicase activity
ccrud_RS06355	COG0488	(ABC) transporter
ccrud_RS06400	COG2197	response regulator
ccrud_RS06405	COG0477	Major facilitator Superfamily
ccrud_RS06410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ccrud_RS06420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ccrud_RS06425	COG0066	3-isopropylmalate dehydratase activity
ccrud_RS06430	COG3311	Transcriptional regulator
ccrud_RS06440	COG0494	nUDIX hydrolase
ccrud_RS06440	COG0406	alpha-ribazole phosphatase activity
ccrud_RS06460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ccrud_RS06465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ccrud_RS06470	COG1461	Dihydroxyacetone kinase
ccrud_RS06475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ccrud_RS06485	COG0742	ribosomal rna small subunit methyltransferase
ccrud_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ccrud_RS06540	COG2226	methyltransferase
ccrud_RS06545	COG0539	negative regulation of cytoplasmic translation
ccrud_RS06550	COG1263	PTS System
ccrud_RS06550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ccrud_RS06550	COG2190	(PTS) system
ccrud_RS06555	COG0237	dephospho-CoA kinase activity
ccrud_RS06580	COG1733	regulation of RNA biosynthetic process
ccrud_RS06585	COG0702	epimerase
ccrud_RS06590	COG3973	AAA domain
ccrud_RS06600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ccrud_RS06615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ccrud_RS06630	COG1175	transmembrane transport
ccrud_RS06645	COG3842	ATPase activity
ccrud_RS06655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ccrud_RS06660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ccrud_RS06665	COG0072	phenylalanine-tRNA ligase activity
ccrud_RS06665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ccrud_RS06685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ccrud_RS06700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ccrud_RS06705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ccrud_RS06715	COG0137	argininosuccinate synthase activity
ccrud_RS06740	COG2835	tetraacyldisaccharide 4'-kinase activity
ccrud_RS06745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ccrud_RS06770	COG0647	UMP catabolic process
ccrud_RS06780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ccrud_RS06805	COG0494	nUDIX hydrolase
ccrud_RS06810	COG4974	Belongs to the 'phage' integrase family
ccrud_RS06830	COG2897	thiosulfate sulfurtransferase activity
ccrud_RS06835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ccrud_RS06845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ccrud_RS06850	COG1160	GTP binding
ccrud_RS06930	COG1132	(ABC) transporter
ccrud_RS06935	COG1132	(ABC) transporter
ccrud_RS06940	COG0428	transporter
ccrud_RS06945	COG0025	NhaP-type Na H and K H
ccrud_RS06955	COG3012	SEC-C Motif Domain Protein
ccrud_RS06965	COG0653	protein targeting
ccrud_RS06970	COG1716	ATPase activity
ccrud_RS07010	COG1253	flavin adenine dinucleotide binding
ccrud_RS07015	COG1253	flavin adenine dinucleotide binding
ccrud_RS07020	COG0513	Belongs to the DEAD box helicase family
ccrud_RS07025	COG1309	transcriptional regulator
ccrud_RS07030	COG1902	pentaerythritol trinitrate reductase activity
ccrud_RS07040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ccrud_RS07055	COG1131	(ABC) transporter
ccrud_RS07070	COG3639	organic phosphonate transmembrane transporter activity
ccrud_RS07075	COG3639	organic phosphonate transmembrane transporter activity
ccrud_RS07080	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ccrud_RS07095	COG0351	phosphomethylpyrimidine kinase
ccrud_RS07095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ccrud_RS07095	COG0352	thiamine-phosphate diphosphorylase activity
ccrud_RS07105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ccrud_RS07115	COG0477	Major facilitator Superfamily
ccrud_RS07120	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ccrud_RS07150	COG0659	secondary active sulfate transmembrane transporter activity
ccrud_RS07175	COG0463	Glycosyl transferase, family 2
ccrud_RS07215	COG0300	oxidoreductase activity
ccrud_RS07230	COG4581	dead DEAH box helicase
ccrud_RS07235	COG0805	protein transport
ccrud_RS07240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ccrud_RS07245	COG2378	regulation of single-species biofilm formation
ccrud_RS07280	COG1362	aminopeptidase activity
ccrud_RS07295	COG2814	Major facilitator Superfamily
ccrud_RS07300	COG1027	Aspartate ammonia-lyase
ccrud_RS07315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ccrud_RS07320	COG1410	methionine synthase
ccrud_RS07320	COG0646	methionine synthase
ccrud_RS07335	COG0798	PFAM Bile acid sodium symporter
ccrud_RS07340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ccrud_RS07380	COG1968	undecaprenyl-diphosphatase activity
ccrud_RS07385	COG0667	Aldo Keto reductase
ccrud_RS07405	COG1881	PFAM PEBP family protein
ccrud_RS07410	COG1132	(ABC) transporter
ccrud_RS07415	COG1132	(ABC) transporter
ccrud_RS07490	COG0791	NLP P60 protein
ccrud_RS07490	COG3883	PFAM NLP P60 protein
ccrud_RS07500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ccrud_RS07505	COG1309	transcriptional regulator
ccrud_RS07545	COG0488	(ABC) transporter
ccrud_RS07550	COG2151	metal-sulfur cluster biosynthetic enzyme
ccrud_RS07555	COG0822	iron-sulfur transferase activity
ccrud_RS07565	COG0396	ATPase activity
ccrud_RS07590	COG1131	(ABC) transporter
ccrud_RS07605	COG0604	alcohol dehydrogenase
ccrud_RS07605	COG3321	synthase
ccrud_RS07605	COG4221	oxidoreductase activity
ccrud_RS07605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ccrud_RS07615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ccrud_RS07620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ccrud_RS07645	COG2423	ornithine cyclodeaminase activity
ccrud_RS07650	COG0004	ammonium transporteR
ccrud_RS07655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ccrud_RS07660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ccrud_RS07665	COG0149	triose-phosphate isomerase activity
ccrud_RS07670	COG0126	phosphoglycerate kinase activity
ccrud_RS07675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ccrud_RS07685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ccrud_RS07695	COG0322	excinuclease ABC activity
ccrud_RS07740	COG0242	peptide deformylase activity
ccrud_RS07745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ccrud_RS07750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ccrud_RS07760	COG1758	RNA polymerase activity
ccrud_RS07765	COG0194	GDP metabolic process
ccrud_RS07780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ccrud_RS07785	COG0505	Belongs to the CarA family
ccrud_RS07790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ccrud_RS07800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ccrud_RS07820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ccrud_RS07830	COG0006	proline dipeptidase activity
ccrud_RS07835	COG2801	Transposase and inactivated derivatives
ccrud_RS07850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ccrud_RS07855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ccrud_RS07875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ccrud_RS07885	COG1120	ATPase activity
ccrud_RS07890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ccrud_RS07895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ccrud_RS07900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ccrud_RS07930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ccrud_RS07940	COG1129	ABC transporter
ccrud_RS07955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS07965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ccrud_RS07970	COG0124	histidyl-tRNA synthetase
ccrud_RS07995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ccrud_RS08000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ccrud_RS08005	COG0747	negative chemotaxis
ccrud_RS08010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ccrud_RS08015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ccrud_RS08030	COG0632	four-way junction helicase activity
ccrud_RS08035	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ccrud_RS08045	COG1946	Acyl-CoA thioesterase
ccrud_RS08065	COG0438	transferase activity, transferring glycosyl groups
ccrud_RS08070	COG1560	Kdo2-lipid A biosynthetic process
ccrud_RS08075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ccrud_RS08085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ccrud_RS08090	COG2837	iron assimilation
ccrud_RS08095	COG2847	Copper chaperone PCu(A)C
ccrud_RS08145	COG0583	DNA-binding transcription factor activity
ccrud_RS08155	COG1929	Belongs to the glycerate kinase type-1 family
ccrud_RS08175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ccrud_RS08180	COG3253	May function as heme-dependent peroxidase
ccrud_RS08190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ccrud_RS08200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ccrud_RS08225	COG0483	inositol monophosphate 1-phosphatase activity
ccrud_RS08240	COG2311	Membrane
ccrud_RS08250	COG1061	Type III restriction enzyme res subunit
ccrud_RS08265	COG2890	protein-(glutamine-N5) methyltransferase activity
ccrud_RS08280	COG1321	iron dependent repressor
ccrud_RS08285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ccrud_RS08305	COG0583	DNA-binding transcription factor activity
ccrud_RS08315	COG1643	Atp-dependent helicase
ccrud_RS08335	COG1349	DNA-binding transcription factor activity
ccrud_RS08345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ccrud_RS08350	COG1349	DNA-binding transcription factor activity
ccrud_RS08355	COG1105	Belongs to the carbohydrate kinase PfkB family
ccrud_RS08360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ccrud_RS08360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ccrud_RS08360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ccrud_RS08375	COG2233	PERMEase
ccrud_RS08380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ccrud_RS08410	COG1196	nuclear chromosome segregation
ccrud_RS08430	COG1126	abc transporter atp-binding protein
ccrud_RS08435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ccrud_RS08440	COG0765	amino acid transport
ccrud_RS08445	COG0765	amino acid transport
ccrud_RS08450	COG2137	regulation of response to DNA damage stimulus
ccrud_RS08465	COG1268	BioY protein
ccrud_RS08470	COG1122	ATPase activity
ccrud_RS08480	COG1842	Phage shock protein A
ccrud_RS08485	COG1396	sequence-specific DNA binding
ccrud_RS08510	COG1674	ftsk spoiiie
ccrud_RS08540	COG1053	succinate dehydrogenase
ccrud_RS08545	COG1802	Transcriptional regulator
ccrud_RS08550	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ccrud_RS08555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ccrud_RS08560	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ccrud_RS08565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ccrud_RS08575	COG1185	polyribonucleotide nucleotidyltransferase activity
ccrud_RS08605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ccrud_RS08615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ccrud_RS08650	COG4166	transmembrane transport
ccrud_RS08655	COG0601	transmembrane transport
ccrud_RS08660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ccrud_RS08665	COG4172	Belongs to the ABC transporter superfamily
ccrud_RS08675	COG3022	response to hydroperoxide
ccrud_RS08690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ccrud_RS08695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ccrud_RS08745	COG2197	response regulator
ccrud_RS08750	COG3850	Histidine kinase
ccrud_RS08755	COG0577	efflux transmembrane transporter activity
ccrud_RS08760	COG1136	(ABC) transporter
ccrud_RS08765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ccrud_RS08770	COG0750	zinc metalloprotease
ccrud_RS08790	COG1131	(ABC) transporter
ccrud_RS08795	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ccrud_RS08820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ccrud_RS08835	COG4974	Belongs to the 'phage' integrase family
ccrud_RS08850	COG0792	nuclease activity
ccrud_RS08860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ccrud_RS08865	COG0681	Belongs to the peptidase S26 family
ccrud_RS08875	COG0352	thiamine-phosphate diphosphorylase activity
ccrud_RS08880	COG2022	thiamine diphosphate biosynthetic process
ccrud_RS08880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ccrud_RS08890	COG2022	thiamine diphosphate biosynthetic process
ccrud_RS08895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ccrud_RS08905	COG1609	Transcriptional regulator
ccrud_RS08910	COG0471	metal ion transport
ccrud_RS08930	COG0336	Belongs to the RNA methyltransferase TrmD family
ccrud_RS08940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ccrud_RS08975	COG1131	(ABC) transporter
ccrud_RS08985	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ccrud_RS09010	COG1196	nuclear chromosome segregation
ccrud_RS09015	COG1254	Belongs to the acylphosphatase family
ccrud_RS09075	COG0571	ribonuclease III activity
ccrud_RS09090	COG1132	(ABC) transporter
ccrud_RS09095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ccrud_RS09100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ccrud_RS09105	COG1929	Belongs to the glycerate kinase type-1 family
ccrud_RS09125	COG0058	SHG alpha-glucan phosphorylase activity
ccrud_RS09130	COG2514	catechol 2,3-dioxygenase activity
ccrud_RS09135	COG0469	pyruvate kinase activity
ccrud_RS09145	COG0134	indole-3-glycerol-phosphate synthase activity
ccrud_RS09165	COG0483	inositol monophosphate 1-phosphatase activity
ccrud_RS09170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ccrud_RS09175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ccrud_RS09200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ccrud_RS09230	COG1120	ATPase activity
ccrud_RS09235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ccrud_RS09295	COG1739	Uncharacterized protein family UPF0029
ccrud_RS09305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ccrud_RS09340	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS09345	COG0019	diaminopimelate decarboxylase activity
ccrud_RS09365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ccrud_RS09375	COG0488	(ABC) transporter
ccrud_RS09385	COG0252	asparaginase activity
ccrud_RS09400	COG0789	Transcriptional regulator
ccrud_RS09410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ccrud_RS09415	COG3599	regulation of cell shape
ccrud_RS09425	COG1799	cell septum assembly
ccrud_RS09430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ccrud_RS09435	COG1496	oxidoreductase activity
ccrud_RS09440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ccrud_RS09445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ccrud_RS09455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ccrud_RS09465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ccrud_RS09470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ccrud_RS09480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ccrud_RS09485	COG0768	penicillin binding
ccrud_RS09495	COG0275	rRNA processing
ccrud_RS09515	COG0456	acetyltransferase
ccrud_RS09525	COG0142	geranyltranstransferase activity
ccrud_RS09540	COG0515	serine threonine protein kinase
ccrud_RS09540	COG2815	serine threonine protein kinase
ccrud_RS09545	COG5650	phosphatidylinositol metabolic process
ccrud_RS09555	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ccrud_RS09585	COG1940	carbohydrate kinase activity
ccrud_RS09590	COG0438	transferase activity, transferring glycosyl groups
ccrud_RS09610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ccrud_RS09615	COG0723	plastoquinol--plastocyanin reductase activity
ccrud_RS09620	COG2010	Cytochrome c
ccrud_RS09625	COG1845	cytochrome c oxidase, subunit III
ccrud_RS09635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ccrud_RS09655	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ccrud_RS09665	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ccrud_RS09685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ccrud_RS09705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ccrud_RS09710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ccrud_RS09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
ccrud_RS09740	COG2985	domain, Protein
ccrud_RS09740	COG0569	domain protein
ccrud_RS09760	COG0174	glutamine synthetase
ccrud_RS09770	COG0494	nUDIX hydrolase
ccrud_RS09775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS09785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ccrud_RS09810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ccrud_RS09815	COG0174	glutamine synthetase
ccrud_RS09840	COG0557	exoribonuclease II activity
ccrud_RS09870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ccrud_RS09870	COG3323	Protein of unknown function (DUF1653)
ccrud_RS09900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ccrud_RS09930	COG2267	carboxylic ester hydrolase activity
ccrud_RS09935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ccrud_RS09985	COG3387	PFAM Glycoside hydrolase 15-related
ccrud_RS10010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ccrud_RS10015	COG0246	Mannitol dehydrogenase
ccrud_RS10020	COG2213	PTS system mannitol-specific
ccrud_RS10020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ccrud_RS10025	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ccrud_RS10050	COG0423	glycine-tRNA ligase activity
ccrud_RS10075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ccrud_RS10080	COG1381	Involved in DNA repair and RecF pathway recombination
ccrud_RS10085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ccrud_RS10110	COG0484	heat shock protein binding
ccrud_RS10140	COG1022	Amp-dependent synthetase and ligase
ccrud_RS10150	COG1132	(ABC) transporter
ccrud_RS10160	COG0339	signal peptide processing
ccrud_RS10170	COG0366	Alpha amylase catalytic
ccrud_RS10175	COG3281	Trehalose synthase
ccrud_RS10205	COG1114	Component of the transport system for branched-chain amino acids
ccrud_RS10210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS10220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ccrud_RS10225	COG3639	organic phosphonate transmembrane transporter activity
ccrud_RS10230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ccrud_RS10235	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ccrud_RS10245	COG2188	Transcriptional regulator
ccrud_RS10260	COG0247	lactate metabolic process
ccrud_RS10260	COG0277	FAD linked oxidase domain protein
ccrud_RS10280	COG0747	negative chemotaxis
ccrud_RS10285	COG0601	transmembrane transport
ccrud_RS10290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ccrud_RS10295	COG4172	Belongs to the ABC transporter superfamily
ccrud_RS10300	COG0583	DNA-binding transcription factor activity
ccrud_RS10305	COG2851	Citrate transporter
ccrud_RS10325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ccrud_RS10335	COG0676	glucose-6-phosphate 1-epimerase activity
ccrud_RS10340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ccrud_RS10345	COG2224	Isocitrate lyase
ccrud_RS10360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ccrud_RS10395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ccrud_RS10405	COG0481	GTPase activity
ccrud_RS10420	COG1280	lysine exporter protein (LysE YggA)
ccrud_RS10445	COG1307	EDD domain protein, DegV family
ccrud_RS10450	COG0406	alpha-ribazole phosphatase activity
ccrud_RS10460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ccrud_RS10480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ccrud_RS10520	COG1530	ribonuclease E activity
ccrud_RS10565	COG0285	dihydrofolate synthase activity
ccrud_RS10570	COG0525	valine-tRNA ligase activity
ccrud_RS10575	COG4166	transmembrane transport
ccrud_RS10580	COG0443	Heat shock 70 kDa protein
ccrud_RS10590	COG0039	L-malate dehydrogenase activity
ccrud_RS10595	COG1309	transcriptional regulator
ccrud_RS10615	COG2814	Major facilitator Superfamily
ccrud_RS10645	COG1414	Transcriptional regulator
ccrud_RS10650	COG0183	Belongs to the thiolase family
ccrud_RS10655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ccrud_RS10665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ccrud_RS10675	COG3485	protocatechuate 3,4-dioxygenase
ccrud_RS10680	COG3485	protocatechuate 3,4-dioxygenase
ccrud_RS10690	COG4829	muconolactone delta-isomerase
ccrud_RS10695	COG4948	Mandelate Racemase Muconate Lactonizing
ccrud_RS10700	COG3485	protocatechuate 3,4-dioxygenase
ccrud_RS10705	COG4638	Rieske (2fe-2S)
ccrud_RS10740	COG0740	serine-type endopeptidase activity
ccrud_RS10745	COG0740	serine-type endopeptidase activity
ccrud_RS10780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ccrud_RS10820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ccrud_RS10835	COG0366	Alpha amylase catalytic
ccrud_RS10840	COG1609	Transcriptional regulator
ccrud_RS10845	COG3842	ATPase activity
ccrud_RS10850	COG3153	acetyltransferase
ccrud_RS10850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ccrud_RS10870	COG0395	ABC-type sugar transport system, permease component
ccrud_RS10875	COG1175	transmembrane transport
ccrud_RS10885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ccrud_RS10900	COG4172	Belongs to the ABC transporter superfamily
ccrud_RS10905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ccrud_RS10910	COG0601	transmembrane transport
ccrud_RS10915	COG0747	negative chemotaxis
ccrud_RS10925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ccrud_RS10950	COG4221	oxidoreductase activity
ccrud_RS10965	COG1119	ATPase activity
ccrud_RS10995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ccrud_RS11010	COG1840	ABC-type Fe3 transport system, periplasmic component
ccrud_RS11015	COG0546	phosphoglycolate phosphatase activity
ccrud_RS11020	COG2188	Transcriptional regulator
ccrud_RS11045	COG1785	Belongs to the alkaline phosphatase family
ccrud_RS11080	COG1606	tRNA processing
ccrud_RS11085	COG1691	(AIR) carboxylase
ccrud_RS11095	COG3622	Belongs to the hyi family
ccrud_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS11115	COG1376	ErfK ybiS ycfS ynhG family protein
ccrud_RS11130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ccrud_RS11145	COG2066	Belongs to the glutaminase family
ccrud_RS11150	COG1609	Transcriptional regulator
ccrud_RS11155	COG1904	glucuronate isomerase
ccrud_RS11160	COG0246	Mannitol dehydrogenase
ccrud_RS11165	COG1102	Psort location Cytoplasmic, score
ccrud_RS11165	COG1904	glucuronate isomerase
ccrud_RS11170	COG3265	gluconokinase activity
ccrud_RS11180	COG1335	isochorismatase
ccrud_RS11205	COG2814	Major facilitator Superfamily
ccrud_RS11220	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ccrud_RS11220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ccrud_RS11220	COG3321	synthase
ccrud_RS11230	COG3835	regulator
ccrud_RS11250	COG1566	PFAM secretion protein HlyD family protein
ccrud_RS11265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ccrud_RS11270	COG1234	tRNA 3'-trailer cleavage
ccrud_RS11275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ccrud_RS11295	COG3191	aminopeptidase activity
ccrud_RS11315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ccrud_RS11340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ccrud_RS11355	COG2186	Transcriptional regulator
ccrud_RS11360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ccrud_RS11370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ccrud_RS11380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ccrud_RS11395	COG0604	alcohol dehydrogenase
ccrud_RS11410	COG0033	Phosphoglucomutase
ccrud_RS11415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ccrud_RS11420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ccrud_RS11435	COG1823	symporter activity
ccrud_RS11440	COG0577	efflux transmembrane transporter activity
ccrud_RS11440	COG1136	(ABC) transporter
ccrud_RS11445	COG1136	(ABC) transporter
ccrud_RS11475	COG0673	inositol 2-dehydrogenase activity
ccrud_RS11485	COG2211	Major facilitator Superfamily
ccrud_RS11505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ccrud_RS11515	COG2197	response regulator
ccrud_RS11525	COG1045	serine acetyltransferase
ccrud_RS11550	COG0045	succinate-CoA ligase (ADP-forming) activity
ccrud_RS11595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ccrud_RS11615	COG0456	acetyltransferase
ccrud_RS11625	COG1597	lipid kinase activity
ccrud_RS11650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ccrud_RS11675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ccrud_RS11680	COG0047	phosphoribosylformylglycinamidine synthase activity
ccrud_RS11685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ccrud_RS11690	COG0386	Belongs to the glutathione peroxidase family
ccrud_RS11705	COG1301	dicarboxylic acid transport
ccrud_RS11720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ccrud_RS11725	COG0436	Aminotransferase
ccrud_RS11730	COG0151	Belongs to the GarS family
ccrud_RS11735	COG0537	adenosine 5'-monophosphoramidase activity
ccrud_RS11740	COG2205	protein histidine kinase activity
ccrud_RS11745	COG0745	RESPONSE REGULATOR receiver
ccrud_RS11750	COG0789	Transcriptional regulator
ccrud_RS11765	COG1309	transcriptional regulator
ccrud_RS11780	COG1053	succinate dehydrogenase
ccrud_RS11785	COG1053	succinate dehydrogenase
ccrud_RS11800	COG0477	Major facilitator Superfamily
ccrud_RS11805	COG0583	DNA-binding transcription factor activity
ccrud_RS11810	COG0657	acetylesterase activity
ccrud_RS11820	COG1748	Saccharopine dehydrogenase
ccrud_RS11850	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ccrud_RS11865	COG1609	Transcriptional regulator
ccrud_RS11875	COG1121	(ABC) transporter
ccrud_RS11880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ccrud_RS11885	COG1053	succinate dehydrogenase
ccrud_RS11895	COG0673	inositol 2-dehydrogenase activity
ccrud_RS11900	COG0477	Major facilitator Superfamily
ccrud_RS11910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ccrud_RS11925	COG1621	beta-fructofuranosidase activity
ccrud_RS11935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ccrud_RS11940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ccrud_RS11960	COG4166	transmembrane transport
ccrud_RS11970	COG0444	Belongs to the ABC transporter superfamily
ccrud_RS11975	COG4608	Belongs to the ABC transporter superfamily
ccrud_RS11985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ccrud_RS11990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ccrud_RS12005	COG2205	protein histidine kinase activity
ccrud_RS12010	COG2847	Copper chaperone PCu(A)C
ccrud_RS12015	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ccrud_RS12050	COG0542	response to heat
ccrud_RS12070	COG2207	Transcriptional regulator
ccrud_RS12080	COG2814	Major facilitator Superfamily
ccrud_RS12095	COG2814	Major facilitator Superfamily
ccrud_RS12105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ccrud_RS12110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ccrud_RS12145	COG0302	gtp cyclohydrolase
ccrud_RS12150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ccrud_RS12160	COG0037	tRNA processing
ccrud_RS12165	COG2027	D-alanyl-D-alanine carboxypeptidase
ccrud_RS12170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ccrud_RS12175	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ccrud_RS12180	COG3766	membrane
ccrud_RS12200	COG3711	transcriptional antiterminator
ccrud_RS12205	COG2723	6-phospho-beta-galactosidase activity
ccrud_RS12220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ccrud_RS12235	COG1012	belongs to the aldehyde dehydrogenase family
ccrud_RS12250	COG2326	polyphosphate kinase activity
ccrud_RS12270	COG1100	Small GTP-binding protein
ccrud_RS12320	COG2111	Na H antiporter
ccrud_RS12320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ccrud_RS12325	COG1006	Multisubunit Na H antiporter MnhC subunit
ccrud_RS12330	COG0651	ATP synthesis coupled electron transport
ccrud_RS12340	COG2212	antiporter activity
ccrud_RS12345	COG1320	monovalent cation:proton antiporter activity
ccrud_RS12370	COG0242	peptide deformylase activity
ccrud_RS12380	COG0708	Exodeoxyribonuclease III
ccrud_RS12390	COG2814	Major facilitator Superfamily
ccrud_RS12400	COG0384	phenazine biosynthesis protein PhzF
ccrud_RS12410	COG1131	(ABC) transporter
ccrud_RS12430	COG0515	serine threonine protein kinase
ccrud_RS12435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ccrud_RS12440	COG0280	phosphate acetyltransferase
ccrud_RS12475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ccrud_RS12485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ccrud_RS12490	COG4129	membrane
ccrud_RS12495	COG0191	fructose-bisphosphate aldolase activity
ccrud_RS12510	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ccrud_RS12540	COG0542	response to heat
ccrud_RS12550	COG2072	flavoprotein involved in K transport
ccrud_RS12555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS12590	COG1012	belongs to the aldehyde dehydrogenase family
ccrud_RS12595	COG0789	Transcriptional regulator
ccrud_RS12600	COG0484	heat shock protein binding
ccrud_RS12605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ccrud_RS12620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ccrud_RS12640	COG0730	response to heat
ccrud_RS12660	COG0175	sulfate reduction
ccrud_RS12665	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ccrud_RS12720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ccrud_RS12725	COG2011	ABC-type metal ion transport system permease component
ccrud_RS12730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ccrud_RS12745	COG1122	ATPase activity
ccrud_RS12800	COG2818	Glycosylase
ccrud_RS12805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ccrud_RS12805	COG1017	nitric oxide dioxygenase activity
ccrud_RS12815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ccrud_RS12830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ccrud_RS12830	COG1263	PTS System
ccrud_RS12830	COG2190	(PTS) system
ccrud_RS12845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ccrud_RS12875	COG0154	amidase activity
ccrud_RS12885	COG4566	intracellular signal transduction
ccrud_RS12890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ccrud_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS12920	COG2205	protein histidine kinase activity
ccrud_RS12935	COG2175	clavaminate synthase activity
ccrud_RS12940	COG0747	negative chemotaxis
ccrud_RS12945	COG0747	negative chemotaxis
ccrud_RS12950	COG0601	transmembrane transport
ccrud_RS12955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ccrud_RS12975	COG1472	Belongs to the glycosyl hydrolase 3 family
ccrud_RS12990	COG4981	capsule polysaccharide biosynthetic process
ccrud_RS12995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ccrud_RS12995	COG2755	lipolytic protein G-D-S-L family
ccrud_RS13010	COG0438	transferase activity, transferring glycosyl groups
ccrud_RS13065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ccrud_RS13070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ccrud_RS13070	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ccrud_RS13070	COG3321	synthase
ccrud_RS13075	COG0318	PFAM AMP-dependent synthetase and ligase
ccrud_RS13080	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ccrud_RS13095	COG2610	gluconate transmembrane transporter activity
ccrud_RS13110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ccrud_RS13115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ccrud_RS13120	COG0671	phosphoesterase, PA-phosphatase related
ccrud_RS13125	COG1216	Glycosyl transferase, family 2
ccrud_RS13135	COG0671	phosphoesterase, PA-phosphatase related
ccrud_RS13165	COG0561	phosphatase activity
ccrud_RS13175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ccrud_RS13180	COG2188	Transcriptional regulator
ccrud_RS13200	COG0077	Prephenate dehydratase
ccrud_RS13205	COG0154	amidase activity
ccrud_RS13220	COG3764	Sortase (surface protein transpeptidase)
ccrud_RS13240	COG1316	TRANSCRIPTIONal
ccrud_RS13255	COG0657	acetylesterase activity
ccrud_RS13260	COG2610	gluconate transmembrane transporter activity
ccrud_RS13265	COG0469	pyruvate kinase activity
ccrud_RS13270	COG0039	L-malate dehydrogenase activity
ccrud_RS13290	COG2188	Transcriptional regulator
ccrud_RS13295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ccrud_RS13300	COG0477	Major facilitator Superfamily
ccrud_RS13340	COG0583	DNA-binding transcription factor activity
ccrud_RS13345	COG2814	Major facilitator Superfamily
ccrud_RS13365	COG2197	response regulator
ccrud_RS13370	COG3850	Histidine kinase
ccrud_RS13385	COG3764	Sortase (surface protein transpeptidase)
ccrud_RS13390	COG0706	membrane insertase activity
ccrud_RS13410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ccrud_RS13450	COG2188	Transcriptional regulator
ccrud_RS13460	COG1842	Phage shock protein A
ccrud_RS13465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ccrud_RS13475	COG0477	Major facilitator Superfamily
ccrud_RS13480	COG1695	Transcriptional regulator
ccrud_RS13485	COG0305	Participates in initiation and elongation during chromosome replication
ccrud_RS13495	COG0629	single-stranded DNA binding
ccrud_RS13500	COG0360	Binds together with S18 to 16S ribosomal RNA
ccrud_RS13515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ccrud_RS13525	COG1846	Transcriptional regulator
ccrud_RS13545	COG1054	Belongs to the UPF0176 family
ccrud_RS13550	COG1260	myo-inositol-1-phosphate synthase
ccrud_RS13555	COG4868	Belongs to the UPF0371 family
ccrud_RS13565	COG1690	Belongs to the RtcB family
ccrud_RS13575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ccrud_RS13610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ccrud_RS13615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ccrud_RS13625	COG0778	Nitroreductase
ccrud_RS13635	COG3093	addiction module antidote protein HigA
ccrud_RS13645	COG0179	Fumarylacetoacetate (FAA) hydrolase
ccrud_RS13655	COG1414	Transcriptional regulator
ccrud_RS13660	COG2814	Major facilitator Superfamily
ccrud_RS13665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ccrud_RS13670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ccrud_RS13690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ccrud_RS13695	COG0512	Glutamine amidotransferase of anthranilate synthase
ccrud_RS13705	COG0135	phosphoribosylanthranilate isomerase activity
ccrud_RS13705	COG0134	indole-3-glycerol-phosphate synthase activity
ccrud_RS13710	COG0133	tryptophan synthase activity
ccrud_RS13715	COG0159	tryptophan synthase activity
ccrud_RS13730	COG1131	(ABC) transporter
ccrud_RS13745	COG1902	pentaerythritol trinitrate reductase activity
ccrud_RS13770	COG3104	oligopeptide transport
ccrud_RS13775	COG1028	Short-chain dehydrogenase reductase Sdr
ccrud_RS13790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ccrud_RS13800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ccrud_RS13805	COG2814	Major facilitator Superfamily
ccrud_RS13810	COG1414	Transcriptional regulator
ccrud_RS13825	COG0477	Major facilitator Superfamily
ccrud_RS13855	COG0351	phosphomethylpyrimidine kinase
ccrud_RS13870	COG1687	branched-chain amino acid
ccrud_RS13875	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ccrud_RS13880	COG1678	Uncharacterized ACR, COG1678
ccrud_RS13885	COG0617	tRNA 3'-terminal CCA addition
ccrud_RS13905	COG1595	DNA-templated transcription, initiation
ccrud_RS13915	COG3118	belongs to the thioredoxin family
ccrud_RS13920	COG3409	Peptidoglycan-binding domain 1 protein
ccrud_RS13920	COG0860	N-Acetylmuramoyl-L-alanine amidase
ccrud_RS13935	COG1192	Involved in chromosome partitioning
ccrud_RS13950	COG0594	ribonuclease P activity
ccrud_RS13955	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ccrud_RS13985	COG0187	DNA topoisomerase II activity