locus-tag	class	description
I6I75_RS00025	COG2017	converts alpha-aldose to the beta-anomer
I6I75_RS00045	COG2272	Belongs to the type-B carboxylesterase lipase family
I6I75_RS00050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I6I75_RS00060	COG1132	(ABC) transporter
I6I75_RS00065	COG0567	Dehydrogenase, E1 component
I6I75_RS00065	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I75_RS00075	COG2239	Acts as a magnesium transporter
I6I75_RS00100	COG1595	DNA-templated transcription, initiation
I6I75_RS00105	COG4122	O-methyltransferase activity
I6I75_RS00115	COG0297	glycogen (starch) synthase activity
I6I75_RS00120	COG3527	Alpha-acetolactate decarboxylase
I6I75_RS00145	COG0463	Glycosyl transferase, family 2
I6I75_RS00150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I6I75_RS00160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I6I75_RS00170	COG1113	amino acid transport
I6I75_RS00180	COG1113	amino acid transport
I6I75_RS00220	COG1217	gtp-binding protein TYPA
I6I75_RS00250	COG1136	(ABC) transporter
I6I75_RS00265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6I75_RS00270	COG0601	transmembrane transport
I6I75_RS00275	COG4166	transmembrane transport
I6I75_RS00280	COG1051	belongs to the nudix hydrolase family
I6I75_RS00285	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
I6I75_RS00295	COG4172	Belongs to the ABC transporter superfamily
I6I75_RS00300	COG4721	ABC-type cobalt transport system, permease component
I6I75_RS00310	COG2354	Protein conserved in bacteria
I6I75_RS00315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
I6I75_RS00320	COG1132	(ABC) transporter
I6I75_RS00325	COG1132	(ABC) transporter
I6I75_RS00330	COG2824	Alkylphosphonate utilization operon protein PhnA
I6I75_RS00340	COG0012	GTP binding
I6I75_RS00375	COG1494	fructose-1,6-bisphosphatase
I6I75_RS00380	COG0114	fumarate hydratase activity
I6I75_RS00450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I6I75_RS00515	COG3956	TIGRFAM MazG family protein
I6I75_RS00520	COG0531	amino acid
I6I75_RS00530	COG1309	transcriptional regulator
I6I75_RS00540	COG2132	Multicopper oxidase
I6I75_RS00545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I6I75_RS00550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
I6I75_RS00555	COG1523	belongs to the glycosyl hydrolase 13 family
I6I75_RS00575	COG2070	2-Nitropropane dioxygenase
I6I75_RS00580	COG0193	aminoacyl-tRNA hydrolase activity
I6I75_RS00590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
I6I75_RS00595	COG0596	Alpha beta hydrolase
I6I75_RS00640	COG2326	polyphosphate kinase activity
I6I75_RS00665	COG0488	(ABC) transporter
I6I75_RS00680	COG3583	domain protein
I6I75_RS00685	COG0084	hydrolase, TatD family'
I6I75_RS00700	COG3949	Membrane
I6I75_RS00705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I6I75_RS00710	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
I6I75_RS00720	COG2259	Doxx family
I6I75_RS00740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I6I75_RS00755	COG1970	mechanosensitive ion channel activity
I6I75_RS00765	COG0521	Mo-molybdopterin cofactor biosynthetic process
I6I75_RS00765	COG0315	cyclic pyranopterin monophosphate synthase activity
I6I75_RS00770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6I75_RS00775	COG2205	protein histidine kinase activity
I6I75_RS00780	COG0745	RESPONSE REGULATOR receiver
I6I75_RS00790	COG0254	rRNA binding
I6I75_RS00820	COG1309	transcriptional regulator
I6I75_RS00830	COG0765	amino acid transport
I6I75_RS00835	COG0765	amino acid transport
I6I75_RS00840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I75_RS00845	COG1126	abc transporter atp-binding protein
I6I75_RS00875	COG1605	Chorismate mutase
I6I75_RS00895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I6I75_RS00905	COG1201	RNA secondary structure unwinding
I6I75_RS00910	COG1218	3'(2'),5'-bisphosphate nucleotidase
I6I75_RS00925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I6I75_RS00980	COG4171	peptide transport system, permease
I6I75_RS00985	COG0601	transmembrane transport
I6I75_RS00990	COG4166	transmembrane transport
I6I75_RS01005	COG0019	diaminopimelate decarboxylase activity
I6I75_RS01010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I6I75_RS01015	COG0534	Mate efflux family protein
I6I75_RS01030	COG3757	hydrolase, family 25
I6I75_RS01040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I6I75_RS01050	COG1024	Enoyl-CoA hydratase
I6I75_RS01055	COG0656	L-ascorbic acid biosynthetic process
I6I75_RS01070	COG0545	Peptidyl-prolyl cis-trans isomerase
I6I75_RS01075	COG0372	Belongs to the citrate synthase family
I6I75_RS01095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I75_RS01100	COG2252	PERMEase
I6I75_RS01120	COG1278	Cold shock
I6I75_RS01125	COG1652	LysM domain
I6I75_RS01195	COG0288	reversible hydration of carbon dioxide
I6I75_RS01210	COG2177	Part of the ABC transporter FtsEX involved in
I6I75_RS01215	COG2884	Cell division ATP-binding protein ftsE
I6I75_RS01220	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
I6I75_RS01230	COG0483	inositol monophosphate 1-phosphatase activity
I6I75_RS01235	COG0483	inositol monophosphate 1-phosphatase activity
I6I75_RS01325	COG3480	Lon protease (S16) C-terminal proteolytic domain
I6I75_RS01360	COG0210	DNA helicase
I6I75_RS01385	COG0513	Belongs to the DEAD box helicase family
I6I75_RS01420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6I75_RS01425	COG2135	peptidase activity
I6I75_RS01435	COG1162	GTPase activity
I6I75_RS01470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I6I75_RS01475	COG1040	competence protein
I6I75_RS01485	COG5002	protein histidine kinase activity
I6I75_RS01490	COG0745	RESPONSE REGULATOR receiver
I6I75_RS01515	COG1482	cell wall glycoprotein biosynthetic process
I6I75_RS01545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
I6I75_RS01555	COG1316	TRANSCRIPTIONal
I6I75_RS01585	COG1120	ATPase activity
I6I75_RS01590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS01615	COG4555	ABC transporter
I6I75_RS01635	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
I6I75_RS01635	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
I6I75_RS01640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I6I75_RS01645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I6I75_RS01655	COG1609	Transcriptional regulator
I6I75_RS01660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I75_RS01665	COG0424	maF-like protein
I6I75_RS01675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I6I75_RS01675	COG2755	lipolytic protein G-D-S-L family
I6I75_RS01680	COG0189	ligase activity
I6I75_RS01685	COG2897	thiosulfate sulfurtransferase activity
I6I75_RS01690	COG4770	biotin carboxylase activity
I6I75_RS01700	COG2814	Major facilitator Superfamily
I6I75_RS01705	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I6I75_RS01715	COG1473	amidohydrolase
I6I75_RS01715	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
I6I75_RS01720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I6I75_RS01755	COG1686	Belongs to the peptidase S11 family
I6I75_RS01760	COG1295	ribonuclease BN
I6I75_RS01765	COG0180	Tryptophanyl-tRNA synthetase
I6I75_RS01785	COG4978	Transcriptional regulator
I6I75_RS01785	COG0789	Transcriptional regulator
I6I75_RS01790	COG2814	Major facilitator Superfamily
I6I75_RS01795	COG2838	Isocitrate dehydrogenase
I6I75_RS01800	COG2873	o-acetylhomoserine
I6I75_RS01810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
I6I75_RS01815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS01855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I6I75_RS01865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I75_RS01865	COG1321	iron dependent repressor
I6I75_RS01870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I75_RS01875	COG1121	(ABC) transporter
I6I75_RS01880	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6I75_RS01895	COG1464	Belongs to the NlpA lipoprotein family
I6I75_RS01900	COG1464	Belongs to the NlpA lipoprotein family
I6I75_RS01910	COG2011	ABC-type metal ion transport system permease component
I6I75_RS01955	COG0516	GMP reductase activity
I6I75_RS02000	COG0456	acetyltransferase
I6I75_RS02025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I6I75_RS02080	COG1674	ftsk spoiiie
I6I75_RS02090	COG1404	Belongs to the peptidase S8 family
I6I75_RS02110	COG0203	ribosomal protein L17
I6I75_RS02155	COG0563	adenylate kinase activity
I6I75_RS02160	COG0201	protein transport
I6I75_RS02165	COG3842	ATPase activity
I6I75_RS02185	COG3833	ABC-type maltose transport systems, permease component
I6I75_RS02190	COG1175	transmembrane transport
I6I75_RS02235	COG0671	phosphoesterase, PA-phosphatase related
I6I75_RS02240	COG0252	asparaginase activity
I6I75_RS02245	COG1760	l-serine dehydratase
I6I75_RS02250	COG0814	amino acid
I6I75_RS02285	COG0747	negative chemotaxis
I6I75_RS02345	COG1302	Protein conserved in bacteria
I6I75_RS02420	COG0701	Predicted permease
I6I75_RS02435	COG1131	(ABC) transporter
I6I75_RS02455	COG2197	response regulator
I6I75_RS02495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I75_RS02500	COG1121	(ABC) transporter
I6I75_RS02510	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6I75_RS02530	COG1902	pentaerythritol trinitrate reductase activity
I6I75_RS02560	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I6I75_RS02585	COG0142	geranyltranstransferase activity
I6I75_RS02590	COG0644	oxidoreductase
I6I75_RS02595	COG0039	L-malate dehydrogenase activity
I6I75_RS02605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I6I75_RS02605	COG0438	transferase activity, transferring glycosyl groups
I6I75_RS02620	COG4948	Mandelate Racemase Muconate Lactonizing
I6I75_RS02625	COG3069	C4-dicarboxylate transmembrane transporter activity
I6I75_RS02635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
I6I75_RS02665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I75_RS02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS02680	COG1120	ATPase activity
I6I75_RS02695	COG0785	Cytochrome C biogenesis protein
I6I75_RS02705	COG0406	alpha-ribazole phosphatase activity
I6I75_RS02720	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I6I75_RS02730	COG2217	Heavy metal translocating P-type atpase
I6I75_RS02745	COG1648	precorrin-2 dehydrogenase activity
I6I75_RS02745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I6I75_RS02775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6I75_RS02775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
I6I75_RS02790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I6I75_RS02810	COG0745	RESPONSE REGULATOR receiver
I6I75_RS02815	COG5002	protein histidine kinase activity
I6I75_RS02830	COG0318	PFAM AMP-dependent synthetase and ligase
I6I75_RS02850	COG1882	Formate acetyltransferase
I6I75_RS02860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6I75_RS02870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
I6I75_RS02880	COG2733	membrane
I6I75_RS02890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I6I75_RS02895	COG1053	succinate dehydrogenase
I6I75_RS02905	COG1396	sequence-specific DNA binding
I6I75_RS02905	COG3800	Transcriptional regulator
I6I75_RS02910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I75_RS02920	COG1505	serine-type exopeptidase activity
I6I75_RS02930	COG1088	dTDP-glucose 4,6-dehydratase activity
I6I75_RS02950	COG0318	PFAM AMP-dependent synthetase and ligase
I6I75_RS02965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I6I75_RS02975	COG1297	OPT oligopeptide transporter protein
I6I75_RS02980	COG1754	DNA topoisomerase type I activity
I6I75_RS02980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I6I75_RS02990	COG1111	helicase
I6I75_RS02990	COG1205	dead DEAH box helicase
I6I75_RS03060	COG0494	nUDIX hydrolase
I6I75_RS03080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I6I75_RS03105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6I75_RS03125	COG4152	abc transporter atp-binding protein
I6I75_RS03145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I6I75_RS03145	COG2111	Na H antiporter
I6I75_RS03155	COG0651	ATP synthesis coupled electron transport
I6I75_RS03205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I6I75_RS03215	COG0527	aspartate kinase activity
I6I75_RS03225	COG1131	(ABC) transporter
I6I75_RS03230	COG0697	spore germination
I6I75_RS03240	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
I6I75_RS03240	COG3266	domain, Protein
I6I75_RS03240	COG4932	domain protein
I6I75_RS03250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I6I75_RS03260	COG2814	Major facilitator Superfamily
I6I75_RS03265	COG0813	purine-nucleoside phosphorylase activity
I6I75_RS03270	COG2390	Transcriptional regulator
I6I75_RS03280	COG0778	Nitroreductase
I6I75_RS03295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
I6I75_RS03300	COG3442	glutamine amidotransferase
I6I75_RS03315	COG2186	Transcriptional regulator
I6I75_RS03325	COG2084	Dehydrogenase
I6I75_RS03330	COG2610	gluconate transmembrane transporter activity
I6I75_RS03355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6I75_RS03370	COG1028	Short-chain dehydrogenase reductase Sdr
I6I75_RS03375	COG1063	alcohol dehydrogenase
I6I75_RS03380	COG3265	gluconokinase activity
I6I75_RS03385	COG2610	gluconate transmembrane transporter activity
I6I75_RS03395	COG0343	queuine tRNA-ribosyltransferase activity
I6I75_RS03400	COG2409	Drug exporters of the RND superfamily
I6I75_RS03420	COG0287	Prephenate dehydrogenase
I6I75_RS03440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6I75_RS03465	COG2190	(PTS) system
I6I75_RS03465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I75_RS03465	COG1263	PTS System
I6I75_RS03470	COG1263	PTS System
I6I75_RS03470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I75_RS03480	COG0471	metal ion transport
I6I75_RS03515	COG0604	alcohol dehydrogenase
I6I75_RS03540	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6I75_RS03545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I75_RS03550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I75_RS03555	COG1121	(ABC) transporter
I6I75_RS03560	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6I75_RS03565	COG1216	Glycosyl transferase, family 2
I6I75_RS03595	COG0277	FAD linked oxidase domain protein
I6I75_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
I6I75_RS03630	COG3590	peptidase
I6I75_RS03640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I6I75_RS03645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I6I75_RS03665	COG2501	S4 domain
I6I75_RS03670	COG0393	Putative heavy-metal-binding
I6I75_RS03675	COG1280	lysine exporter protein (LysE YggA)
I6I75_RS03685	COG0519	Catalyzes the synthesis of GMP from XMP
I6I75_RS03695	COG0110	maltose O-acetyltransferase activity
I6I75_RS03700	COG1643	Atp-dependent helicase
I6I75_RS03705	COG3037	sugar-specific permease SgaT UlaA
I6I75_RS03715	COG0730	response to heat
I6I75_RS03725	COG3180	Ammonia monooxygenase
I6I75_RS03740	COG1846	Transcriptional regulator
I6I75_RS03765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I6I75_RS03805	COG1518	maintenance of DNA repeat elements
I6I75_RS03805	COG1468	defense response to virus
I6I75_RS03825	COG3177	Filamentation induced by cAMP protein fic
I6I75_RS03830	COG0477	Major facilitator Superfamily
I6I75_RS03850	COG3757	hydrolase, family 25
I6I75_RS03850	COG3409	Peptidoglycan-binding domain 1 protein
I6I75_RS03865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I6I75_RS03885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I6I75_RS03910	COG2197	response regulator
I6I75_RS03935	COG0517	IMP dehydrogenase activity
I6I75_RS03935	COG1125	glycine betaine transport
I6I75_RS03995	COG2197	response regulator
I6I75_RS04005	COG1131	(ABC) transporter
I6I75_RS04015	COG0366	Alpha amylase catalytic
I6I75_RS04020	COG2239	Acts as a magnesium transporter
I6I75_RS04025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS04030	COG1120	ATPase activity
I6I75_RS04050	COG2897	thiosulfate sulfurtransferase activity
I6I75_RS04075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I6I75_RS04085	COG1716	ATPase activity
I6I75_RS04085	COG1716	ATPase activity
I6I75_RS04105	COG0768	penicillin binding
I6I75_RS04110	COG0515	serine threonine protein kinase
I6I75_RS04115	COG2815	serine threonine protein kinase
I6I75_RS04115	COG0515	serine threonine protein kinase
I6I75_RS04125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6I75_RS04130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS04135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS04140	COG1120	ATPase activity
I6I75_RS04185	COG1518	maintenance of DNA repeat elements
I6I75_RS04270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I6I75_RS04290	COG0187	DNA topoisomerase II activity
I6I75_RS04305	COG0592	DNA-directed DNA polymerase activity
I6I75_RS04315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
I6I75_RS04325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
I6I75_RS04340	COG1192	Involved in chromosome partitioning
I6I75_RS04355	COG0860	N-Acetylmuramoyl-L-alanine amidase
I6I75_RS04355	COG3409	Peptidoglycan-binding domain 1 protein
I6I75_RS04390	COG0617	tRNA 3'-terminal CCA addition
I6I75_RS04395	COG1678	Uncharacterized ACR, COG1678
I6I75_RS04400	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I6I75_RS04430	COG0133	tryptophan synthase activity
I6I75_RS04435	COG0135	phosphoribosylanthranilate isomerase activity
I6I75_RS04435	COG0134	indole-3-glycerol-phosphate synthase activity
I6I75_RS04445	COG0512	Glutamine amidotransferase of anthranilate synthase
I6I75_RS04450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I6I75_RS04470	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
I6I75_RS04485	COG3422	double-strand break repair
I6I75_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
I6I75_RS04555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I6I75_RS04560	COG4608	Belongs to the ABC transporter superfamily
I6I75_RS04565	COG0444	Belongs to the ABC transporter superfamily
I6I75_RS04570	COG0601	transmembrane transport
I6I75_RS04575	COG0747	negative chemotaxis
I6I75_RS04580	COG2186	Transcriptional regulator
I6I75_RS04585	COG1940	carbohydrate kinase activity
I6I75_RS04595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
I6I75_RS04625	COG2197	response regulator
I6I75_RS04630	COG3851	Histidine kinase
I6I75_RS04655	COG1511	domain protein
I6I75_RS04665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
I6I75_RS04665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I6I75_RS04670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I6I75_RS04675	COG0783	Belongs to the Dps family
I6I75_RS04685	COG0586	Pfam SNARE associated Golgi protein
I6I75_RS04700	COG4221	oxidoreductase activity
I6I75_RS04720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6I75_RS04740	COG0629	single-stranded DNA binding
I6I75_RS04750	COG3387	PFAM Glycoside hydrolase 15-related
I6I75_RS04755	COG0305	Participates in initiation and elongation during chromosome replication
I6I75_RS04760	COG0477	Major facilitator Superfamily
I6I75_RS04780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6I75_RS04785	COG1842	Phage shock protein A
I6I75_RS04820	COG0564	pseudouridine synthase activity
I6I75_RS04850	COG0706	membrane insertase activity
I6I75_RS04855	COG3764	Sortase (surface protein transpeptidase)
I6I75_RS04875	COG2197	response regulator
I6I75_RS04895	COG5650	phosphatidylinositol metabolic process
I6I75_RS04900	COG2814	Major facilitator Superfamily
I6I75_RS04905	COG0583	DNA-binding transcription factor activity
I6I75_RS04910	COG0431	NADPH-dependent FMN reductase
I6I75_RS04955	COG1115	amino acid carrier protein
I6I75_RS04970	COG1316	TRANSCRIPTIONal
I6I75_RS04985	COG0077	Prephenate dehydratase
I6I75_RS05005	COG2188	Transcriptional regulator
I6I75_RS05020	COG0561	phosphatase activity
I6I75_RS05030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6I75_RS05035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS05040	COG1120	ATPase activity
I6I75_RS05050	COG2271	Major facilitator Superfamily
I6I75_RS05055	COG0584	glycerophosphoryl diester phosphodiesterase
I6I75_RS05060	COG0671	phosphoesterase, PA-phosphatase related
I6I75_RS05070	COG1216	Glycosyl transferase, family 2
I6I75_RS05075	COG0671	phosphoesterase, PA-phosphatase related
I6I75_RS05080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
I6I75_RS05085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
I6I75_RS05095	COG5650	phosphatidylinositol metabolic process
I6I75_RS05100	COG5479	isomerase activity
I6I75_RS05100	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
I6I75_RS05110	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
I6I75_RS05115	COG0318	PFAM AMP-dependent synthetase and ligase
I6I75_RS05120	COG3321	synthase
I6I75_RS05120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I6I75_RS05120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I6I75_RS05125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I6I75_RS05170	COG0500	methyltransferase
I6I75_RS05185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I6I75_RS05185	COG2755	lipolytic protein G-D-S-L family
I6I75_RS05190	COG4981	capsule polysaccharide biosynthetic process
I6I75_RS05200	COG1472	Belongs to the glycosyl hydrolase 3 family
I6I75_RS05220	COG1129	ABC transporter
I6I75_RS05230	COG1132	(ABC) transporter
I6I75_RS05240	COG1012	belongs to the aldehyde dehydrogenase family
I6I75_RS05255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I6I75_RS05275	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
I6I75_RS05275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
I6I75_RS05295	COG0831	urea catabolic process
I6I75_RS05300	COG0832	Belongs to the urease beta subunit family
I6I75_RS05305	COG0804	urea catabolic process
I6I75_RS05310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
I6I75_RS05315	COG0830	nickel cation binding
I6I75_RS05320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
I6I75_RS05325	COG0829	nickel cation binding
I6I75_RS05335	COG4139	cobalamin transport
I6I75_RS05340	COG1120	ATPase activity
I6I75_RS05355	COG2181	nitrate reductase activity
I6I75_RS05355	COG0247	lactate metabolic process
I6I75_RS05375	COG0601	transmembrane transport
I6I75_RS05380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6I75_RS05410	COG0443	Heat shock 70 kDa protein
I6I75_RS05425	COG0789	Transcriptional regulator
I6I75_RS05440	COG1012	belongs to the aldehyde dehydrogenase family
I6I75_RS05455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6I75_RS05460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I75_RS05465	COG1136	(ABC) transporter
I6I75_RS05470	COG0577	efflux transmembrane transporter activity
I6I75_RS05470	COG1136	(ABC) transporter
I6I75_RS05525	COG1131	(ABC) transporter
I6I75_RS05565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I6I75_RS05580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
I6I75_RS05595	COG0191	fructose-bisphosphate aldolase activity
I6I75_RS05630	COG4129	membrane
I6I75_RS05640	COG4129	membrane
I6I75_RS05655	COG3005	denitrification pathway
I6I75_RS05660	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
I6I75_RS05675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I75_RS05720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
I6I75_RS05725	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
I6I75_RS05745	COG0280	phosphate acetyltransferase
I6I75_RS05760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I75_RS05775	COG1131	(ABC) transporter
I6I75_RS05785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6I75_RS05790	COG0708	Exodeoxyribonuclease III
I6I75_RS05800	COG0242	peptide deformylase activity
I6I75_RS05820	COG1051	belongs to the nudix hydrolase family
I6I75_RS05840	COG0651	ATP synthesis coupled electron transport
I6I75_RS05845	COG1006	Multisubunit Na H antiporter MnhC subunit
I6I75_RS05850	COG2111	Na H antiporter
I6I75_RS05850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I6I75_RS05890	COG2326	polyphosphate kinase activity
I6I75_RS05920	COG1301	dicarboxylic acid transport
I6I75_RS05925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6I75_RS05930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
I6I75_RS05935	COG2027	D-alanyl-D-alanine carboxypeptidase
I6I75_RS05940	COG0037	tRNA processing
I6I75_RS05945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I6I75_RS05950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I6I75_RS05955	COG0302	gtp cyclohydrolase
I6I75_RS05990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
I6I75_RS05995	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
I6I75_RS06000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I6I75_RS06005	COG1012	belongs to the aldehyde dehydrogenase family
I6I75_RS06010	COG1301	dicarboxylic acid transport
I6I75_RS06025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
I6I75_RS06050	COG1957	nucleoside hydrolase
I6I75_RS06055	COG0477	Major facilitator Superfamily
I6I75_RS06065	COG0542	response to heat
I6I75_RS06085	COG0288	reversible hydration of carbon dioxide
I6I75_RS06095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I6I75_RS06105	COG2847	Copper chaperone PCu(A)C
I6I75_RS06110	COG1329	Transcriptional regulator
I6I75_RS06130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I75_RS06140	COG1609	Transcriptional regulator
I6I75_RS06185	COG0028	Belongs to the TPP enzyme family
I6I75_RS06210	COG0477	Major facilitator Superfamily
I6I75_RS06215	COG0745	RESPONSE REGULATOR receiver
I6I75_RS06220	COG2205	protein histidine kinase activity
I6I75_RS06230	COG0537	adenosine 5'-monophosphoramidase activity
I6I75_RS06235	COG0151	Belongs to the GarS family
I6I75_RS06240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I6I75_RS06245	COG0569	domain protein
I6I75_RS06250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I6I75_RS06270	COG0386	Belongs to the glutathione peroxidase family
I6I75_RS06275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I6I75_RS06280	COG0047	phosphoribosylformylglycinamidine synthase activity
I6I75_RS06285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I6I75_RS06295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6I75_RS06300	COG1780	Probably involved in ribonucleotide reductase function
I6I75_RS06325	COG0354	folic acid binding
I6I75_RS06340	COG1597	lipid kinase activity
I6I75_RS06370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I6I75_RS06395	COG4988	ABC transporter
I6I75_RS06400	COG4988	ABC transporter
I6I75_RS06405	COG1294	oxidase, subunit
I6I75_RS06410	COG1271	oxidase subunit
I6I75_RS06430	COG0371	Dehydrogenase
I6I75_RS06450	COG1045	serine acetyltransferase
I6I75_RS06460	COG2197	response regulator
I6I75_RS06490	COG0577	efflux transmembrane transporter activity
I6I75_RS06490	COG1136	(ABC) transporter
I6I75_RS06495	COG1136	(ABC) transporter
I6I75_RS06495	COG0577	efflux transmembrane transporter activity
I6I75_RS06510	COG0033	Phosphoglucomutase
I6I75_RS06600	COG2217	Heavy metal translocating P-type atpase
I6I75_RS06605	COG0640	Transcriptional regulator
I6I75_RS06635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
I6I75_RS06655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6I75_RS06665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6I75_RS06725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
I6I75_RS06750	COG1234	tRNA 3'-trailer cleavage
I6I75_RS06785	COG2197	response regulator
I6I75_RS06830	COG1335	isochorismatase
I6I75_RS06835	COG2130	NADP-dependent
I6I75_RS06845	COG1376	ErfK ybiS ycfS ynhG family protein
I6I75_RS06870	COG0604	alcohol dehydrogenase
I6I75_RS06895	COG1966	Carbon starvation protein
I6I75_RS06900	COG3336	cytochrome c oxidase
I6I75_RS06905	COG1131	(ABC) transporter
I6I75_RS06985	COG0668	transmembrane transport
I6I75_RS06995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I6I75_RS07030	COG0544	peptidyl-prolyl cis-trans isomerase activity
I6I75_RS07070	COG0285	dihydrofolate synthase activity
I6I75_RS07080	COG2423	ornithine cyclodeaminase activity
I6I75_RS07100	COG1530	ribonuclease E activity
I6I75_RS07130	COG2832	Protein of unknown function (DUF454)
I6I75_RS07145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
I6I75_RS07155	COG0406	alpha-ribazole phosphatase activity
I6I75_RS07160	COG1307	EDD domain protein, DegV family
I6I75_RS07185	COG1280	lysine exporter protein (LysE YggA)
I6I75_RS07210	COG1116	anion transmembrane transporter activity
I6I75_RS07215	COG4172	Belongs to the ABC transporter superfamily
I6I75_RS07235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
I6I75_RS07240	COG2391	methyltransferase activity
I6I75_RS07245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I6I75_RS07255	COG4172	Belongs to the ABC transporter superfamily
I6I75_RS07260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6I75_RS07265	COG0601	transmembrane transport
I6I75_RS07270	COG0747	negative chemotaxis
I6I75_RS07285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I6I75_RS07295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I6I75_RS07300	COG1114	Component of the transport system for branched-chain amino acids
I6I75_RS07305	COG1132	(ABC) transporter
I6I75_RS07355	COG1022	Amp-dependent synthetase and ligase
I6I75_RS07410	COG1381	Involved in DNA repair and RecF pathway recombination
I6I75_RS07435	COG0423	glycine-tRNA ligase activity
I6I75_RS07505	COG2860	membrane
I6I75_RS07530	COG0596	Alpha beta hydrolase
I6I75_RS07535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
I6I75_RS07550	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
I6I75_RS07575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
I6I75_RS07575	COG3323	Protein of unknown function (DUF1653)
I6I75_RS07595	COG0557	exoribonuclease II activity
I6I75_RS07620	COG0174	glutamine synthetase
I6I75_RS07650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I6I75_RS07665	COG2056	Na+-H+ antiporter family
I6I75_RS07670	COG3237	CsbD-like
I6I75_RS07710	COG0174	glutamine synthetase
I6I75_RS07735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS07740	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS07745	COG1120	ATPase activity
I6I75_RS07765	COG0509	glycine decarboxylation via glycine cleavage system
I6I75_RS07770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
I6I75_RS07775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I6I75_RS07775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I6I75_RS07780	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I75_RS07795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I6I75_RS07805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
I6I75_RS07860	COG0791	NLP P60 protein
I6I75_RS07870	COG0438	transferase activity, transferring glycosyl groups
I6I75_RS07875	COG1940	carbohydrate kinase activity
I6I75_RS07895	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
I6I75_RS07900	COG0515	serine threonine protein kinase
I6I75_RS07900	COG2815	serine threonine protein kinase
I6I75_RS07915	COG0142	geranyltranstransferase activity
I6I75_RS07955	COG0768	penicillin binding
I6I75_RS07960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I6I75_RS07990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I6I75_RS07995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
I6I75_RS08000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I6I75_RS08005	COG1496	oxidoreductase activity
I6I75_RS08010	COG1799	cell septum assembly
I6I75_RS08020	COG3599	regulation of cell shape
I6I75_RS08040	COG0252	asparaginase activity
I6I75_RS08055	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
I6I75_RS08080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I6I75_RS08085	COG1739	Uncharacterized protein family UPF0029
I6I75_RS08110	COG2176	DNA-directed DNA polymerase activity
I6I75_RS08175	COG0483	inositol monophosphate 1-phosphatase activity
I6I75_RS08195	COG0134	indole-3-glycerol-phosphate synthase activity
I6I75_RS08205	COG0469	pyruvate kinase activity
I6I75_RS08215	COG0058	SHG alpha-glucan phosphorylase activity
I6I75_RS08240	COG1929	Belongs to the glycerate kinase type-1 family
I6I75_RS08245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I6I75_RS08250	COG0686	Belongs to the AlaDH PNT family
I6I75_RS08280	COG1115	amino acid carrier protein
I6I75_RS08285	COG1254	Belongs to the acylphosphatase family
I6I75_RS08310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
I6I75_RS08330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
I6I75_RS08335	COG0336	Belongs to the RNA methyltransferase TrmD family
I6I75_RS08345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I75_RS08345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I75_RS08345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I75_RS08360	COG0681	Belongs to the peptidase S26 family
I6I75_RS08375	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I6I75_RS08375	COG0352	thiamine-phosphate diphosphorylase activity
I6I75_RS08375	COG0351	phosphomethylpyrimidine kinase
I6I75_RS08380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I6I75_RS08385	COG2022	thiamine diphosphate biosynthetic process
I6I75_RS08395	COG2022	thiamine diphosphate biosynthetic process
I6I75_RS08395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I6I75_RS08400	COG0352	thiamine-phosphate diphosphorylase activity
I6I75_RS08410	COG0792	nuclease activity
I6I75_RS08425	COG4974	Belongs to the 'phage' integrase family
I6I75_RS08480	COG0750	zinc metalloprotease
I6I75_RS08490	COG0768	penicillin binding
I6I75_RS08545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I6I75_RS08545	COG2169	Transcriptional regulator
I6I75_RS08550	COG0523	cobalamin synthesis protein
I6I75_RS08555	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
I6I75_RS08560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I6I75_RS08560	COG1648	precorrin-2 dehydrogenase activity
I6I75_RS08565	COG3022	response to hydroperoxide
I6I75_RS08610	COG0534	Mate efflux family protein
I6I75_RS08615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I6I75_RS08625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
I6I75_RS08665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I6I75_RS08675	COG1674	ftsk spoiiie
I6I75_RS08695	COG1546	Belongs to the CinA family
I6I75_RS08695	COG1058	Belongs to the CinA family
I6I75_RS08700	COG1396	sequence-specific DNA binding
I6I75_RS08705	COG1842	Phage shock protein A
I6I75_RS08710	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I6I75_RS08715	COG1122	ATPase activity
I6I75_RS08720	COG1268	BioY protein
I6I75_RS08730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
I6I75_RS08735	COG2137	regulation of response to DNA damage stimulus
I6I75_RS08755	COG1196	nuclear chromosome segregation
I6I75_RS08770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
I6I75_RS08785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I6I75_RS08790	COG2233	PERMEase
I6I75_RS08805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I6I75_RS08810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I75_RS08815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I75_RS08815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I75_RS08815	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I6I75_RS08825	COG1349	DNA-binding transcription factor activity
I6I75_RS08830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6I75_RS08835	COG1349	DNA-binding transcription factor activity
I6I75_RS08855	COG1643	Atp-dependent helicase
I6I75_RS08870	COG0450	alkyl hydroperoxide reductase
I6I75_RS08875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6I75_RS09000	COG3253	May function as heme-dependent peroxidase
I6I75_RS09005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I6I75_RS09075	COG2837	iron assimilation
I6I75_RS09090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I6I75_RS09095	COG1560	Kdo2-lipid A biosynthetic process
I6I75_RS09100	COG0438	transferase activity, transferring glycosyl groups
I6I75_RS09110	COG0156	8-amino-7-oxononanoate synthase activity
I6I75_RS09125	COG1946	Acyl-CoA thioesterase
I6I75_RS09135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
I6I75_RS09155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6I75_RS09160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6I75_RS09165	COG0747	negative chemotaxis
I6I75_RS09175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6I75_RS09190	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I6I75_RS09195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I6I75_RS09205	COG1760	l-serine dehydratase
I6I75_RS09260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
I6I75_RS09280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
I6I75_RS09290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
I6I75_RS09295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
I6I75_RS09300	COG0006	proline dipeptidase activity
I6I75_RS09325	COG1090	epimerase
I6I75_RS09340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I6I75_RS09350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I6I75_RS09390	COG0242	peptide deformylase activity
I6I75_RS09435	COG0322	excinuclease ABC activity
I6I75_RS09445	COG0391	Required for morphogenesis under gluconeogenic growth conditions
I6I75_RS09455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I6I75_RS09475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I6I75_RS09495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I6I75_RS09500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I6I75_RS09545	COG0396	ATPase activity
I6I75_RS09555	COG0822	iron-sulfur transferase activity
I6I75_RS09560	COG2151	metal-sulfur cluster biosynthetic enzyme
I6I75_RS09580	COG2848	UPF0210 protein
I6I75_RS09610	COG3883	PFAM NLP P60 protein
I6I75_RS09610	COG0791	NLP P60 protein
I6I75_RS09675	COG0488	(ABC) transporter
I6I75_RS09685	COG2376	Dihydroxyacetone kinase
I6I75_RS09690	COG1461	Dihydroxyacetone kinase
I6I75_RS09700	COG1881	PFAM PEBP family protein
I6I75_RS09715	COG0167	dihydroorotate dehydrogenase activity
I6I75_RS09725	COG0667	Aldo Keto reductase
I6I75_RS09745	COG0646	methionine synthase
I6I75_RS09745	COG1410	methionine synthase
I6I75_RS09750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I75_RS09765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6I75_RS09770	COG1027	Aspartate ammonia-lyase
I6I75_RS09790	COG1362	aminopeptidase activity
I6I75_RS09805	COG4122	O-methyltransferase activity
I6I75_RS09825	COG2378	regulation of single-species biofilm formation
I6I75_RS09835	COG0805	protein transport
I6I75_RS09850	COG0300	oxidoreductase activity
I6I75_RS09905	COG0463	Glycosyl transferase, family 2
I6I75_RS09935	COG0277	FAD linked oxidase domain protein
I6I75_RS09940	COG0477	Major facilitator Superfamily
I6I75_RS09960	COG0598	Magnesium transport protein CorA
I6I75_RS09970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I6I75_RS09975	COG0513	Belongs to the DEAD box helicase family
I6I75_RS09980	COG1253	flavin adenine dinucleotide binding
I6I75_RS10030	COG3012	SEC-C Motif Domain Protein
I6I75_RS10050	COG4264	IucA IucC family
I6I75_RS10055	COG1120	ATPase activity
I6I75_RS10060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS10070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
I6I75_RS10075	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
I6I75_RS10080	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
I6I75_RS10085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I6I75_RS10090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6I75_RS10095	COG1160	GTP binding
I6I75_RS10110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I6I75_RS10120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I6I75_RS10125	COG3104	oligopeptide transport
I6I75_RS10145	COG4974	Belongs to the 'phage' integrase family
I6I75_RS10150	COG0494	nUDIX hydrolase
I6I75_RS10180	COG0647	UMP catabolic process
I6I75_RS10210	COG2835	tetraacyldisaccharide 4'-kinase activity
I6I75_RS10215	COG0165	Argininosuccinate lyase
I6I75_RS10230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I6I75_RS10235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I6I75_RS10265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I75_RS10280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
I6I75_RS10295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I6I75_RS10305	COG3973	AAA domain
I6I75_RS10335	COG0539	negative regulation of cytoplasmic translation
I6I75_RS10365	COG0765	amino acid transport
I6I75_RS10390	COG0742	ribosomal rna small subunit methyltransferase
I6I75_RS10395	COG0511	ligase activity, forming carbon-carbon bonds
I6I75_RS10405	COG1461	Dihydroxyacetone kinase
I6I75_RS10410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
I6I75_RS10415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I6I75_RS10435	COG0406	alpha-ribazole phosphatase activity
I6I75_RS10435	COG0494	nUDIX hydrolase
I6I75_RS10470	COG4608	Belongs to the ABC transporter superfamily
I6I75_RS10475	COG0444	Belongs to the ABC transporter superfamily
I6I75_RS10480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6I75_RS10485	COG0601	transmembrane transport
I6I75_RS10500	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
I6I75_RS10535	COG0179	Fumarylacetoacetate (FAA) hydrolase
I6I75_RS10555	COG0473	3-isopropylmalate dehydrogenase activity
I6I75_RS10595	COG0028	Belongs to the TPP enzyme family
I6I75_RS10600	COG0668	transmembrane transport
I6I75_RS10625	COG0435	Glutathione S-transferase
I6I75_RS10630	COG0583	DNA-binding transcription factor activity
I6I75_RS10640	COG0667	Aldo Keto reductase
I6I75_RS10650	COG0205	6-phosphofructokinase activity
I6I75_RS10670	COG1120	ATPase activity
I6I75_RS10675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I75_RS10740	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I6I75_RS10760	COG1119	ATPase activity
I6I75_RS10785	COG0346	lactoylglutathione lyase activity
I6I75_RS10830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
I6I75_RS10835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
I6I75_RS10840	COG0356	it plays a direct role in the translocation of protons across the membrane
I6I75_RS10890	COG0460	homoserine dehydrogenase
I6I75_RS10895	COG0019	diaminopimelate decarboxylase activity
I6I75_RS10905	COG1620	l-lactate permease
I6I75_RS10910	COG0247	lactate metabolic process
I6I75_RS10915	COG1139	Iron-sulfur cluster binding protein
I6I75_RS10920	COG1556	Lactate utilization protein
I6I75_RS10950	COG1846	Transcriptional regulator
I6I75_RS10975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I6I75_RS10980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family