locus_tag old_locus_tag gene Name start end strand product note type ID NCBI AFK63_RS00005 AFK63_00005 malQ malQ 4362039 4364138 + 4-alpha-glucanotransferase amylomaltase%3B acts to release glucose from maltodextrins gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00005 AFK63_RS00010 AFK63_00010 AFK63_RS00010 298 510 + cold-shock protein gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00010 AFK63_RS00015 AFK63_00015 AFK63_RS00015 670 1245 - fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00015 AFK63_RS00020 AFK63_00020 AFK63_RS00020 1304 1945 - phosphoribosyltransferase gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00020 AFK63_RS00025 AFK63_00025 AFK63_RS00025 2021 2800 + pimeloyl-[acyl-carrier protein] methyl ester esterase Shows carboxylesterase activity with a preference for short chain fatty acid esters%3B involved in pimeloyl-CoA synthesis gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00025 AFK63_RS00030 AFK63_00030 AFK63_RS00030 2885 3154 + hypothetical protein gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00030 AFK63_RS00035 AFK63_00035 AFK63_RS00035 3188 3424 - ferrous iron transporter C regulatory protein that controls transcription of feoABC genes gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00035 AFK63_RS00040 AFK63_00040 feoB feoB 3424 5739 - ferrous iron transporter B cytoplasmic membrane ferrous uptake system permease%3B mutations disrupt the ability of Escherichia coli to take up ferrous iron%3B GTP-binding protein which requires GTP for efficient iron(II) uptake gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00040 AFK63_RS00045 AFK63_00045 feoA feoA 5766 5990 - ferrous iron transporter A gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00045 AFK63_RS00050 AFK63_00050 AFK63_RS00050 6258 6470 + hypothetical protein gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00050 AFK63_RS00055 AFK63_00055 AFK63_RS00055 6589 8913 - transcription accessory protein gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00055 AFK63_RS00060 AFK63_00060 greB greB 9026 9499 - transcription elongation factor GreB necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00060 AFK63_RS00065 AFK63_00065 ompR ompR 9843 10562 + two-component system response regulator part of two-component system EnvZ/OmpR%3B regulates transcription of outer membrane porin genes ompC/F%3B under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR%3B the result is increased expression of ompC and repression of ompF%3B also functions in regulation of other genes%3B forms dimers upon phosphorylation gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00065 AFK63_RS00070 AFK63_00070 envZ envZ 10559 11905 + two-component system sensor histidine kinase membrane-localized osmosensor%3B histidine kinase%3B in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00070 AFK63_RS00075 AFK63_00075 AFK63_RS00075 11963 13582 - phosphoenolpyruvate carboxykinase PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00075 AFK63_RS00080 AFK63_00080 AFK63_RS00080 14011 15723 + hypothetical protein gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00080 AFK63_RS00085 AFK63_00085 hslO hslO 15774 16652 - molecular chaperone Hsp33 becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00085 AFK63_RS00090 AFK63_00090 AFK63_RS00090 16676 17077 - heat-shock protein Hsp15 gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00090 AFK63_RS00095 AFK63_00095 AFK63_RS00095 17077 17757 - nucleotidase gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00095 AFK63_RS00100 AFK63_00100 AFK63_RS00100 17820 19958 - intracellular growth attenuator protein IgaA gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00100 AFK63_RS00105 AFK63_00105 nudE nudE 20296 20856 + adenosine nucleotide hydrolase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00105 AFK63_RS00110 AFK63_00110 mrcA mrcA 20935 23487 - penicillin-binding protein 1A bifunctional murein transglycosylase/murein transpeptidase%3B penicillin-binding protein 1A%3B involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation%3B penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00110 AFK63_RS00115 AFK63_00115 AFK63_RS00115 23607 24398 + pilus assembly protein gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00115 AFK63_RS00120 AFK63_00120 AFK63_RS00120 24398 24949 + pilus assembly protein HofN gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00120 AFK63_RS00125 AFK63_00125 AFK63_RS00125 24933 25409 + hypothetical protein gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00125 AFK63_RS00130 AFK63_00130 AFK63_RS00130 25429 25806 + hypothetical protein gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00130 AFK63_RS00135 AFK63_00135 hofQ hofQ 25796 26971 + porin outer membrane porin probably involved in uptake of extracellular double-stranded DNA%3B similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00135 AFK63_RS00140 AFK63_00140 aroK aroK 27267 27788 + shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00140 AFK63_RS00145 AFK63_00145 aroB aroB 27845 28933 + 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00145 AFK63_RS00150 AFK63_00150 AFK63_RS00150 29026 30339 + cell division protein DamX binds the septal ring gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00150 AFK63_RS00155 AFK63_00155 AFK63_RS00155 30410 31228 + DNA adenine methylase gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00155 AFK63_RS00160 AFK63_00160 AFK63_RS00160 31273 31950 + ribulose-phosphate 3-epimerase gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00160 AFK63_RS00165 AFK63_00165 AFK63_RS00165 31943 32701 + phosphoglycolate phosphatase catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00165 AFK63_RS00170 AFK63_00170 AFK63_RS00170 32694 33698 + tryptophanyl-tRNA synthetase gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00170 AFK63_RS00175 AFK63_00175 AFK63_RS00175 34116 34847 - transcriptional regulator may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM%2C yhfN%2C yhfO%2C yhfP%2C yhfQ%2C and yhfR genes gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00175 AFK63_RS00180 AFK63_00180 AFK63_RS00180 34949 35734 - fructoselysine kinase gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00180 AFK63_RS00185 AFK63_00185 AFK63_RS00185 35731 36561 - fructoselysine 3-epimerase YhfOP%3B YhfP%3B YhfO%3B FrlC%3B catalyzes the interconversion of fructoselysine and psicoselysine gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00185 AFK63_RS00190 AFK63_00190 frlB frlB 36612 37634 - fructoselysine-6-P-deglycase catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00190 AFK63_RS00195 AFK63_00195 frlA frlA 37656 38996 - fructoselysine transporter inner membrane protein possibly involved in fructoselysine transport%3B member of the flr operon gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00195 AFK63_RS00200 AFK63_00200 cysG cysG 39280 40653 - siroheme synthase multifunction enzyme consisting of uroporphyrin-III C-methyltransferase%2C precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase%3B catalyzes the methylation of uroporphyrinogen III to form precorrin-2%2C then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00200 AFK63_RS00205 AFK63_00205 AFK63_RS00205 40666 41469 - nitrite transporter NirC member of the FNT family of formate and nitrite transporters gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00205 AFK63_RS00210 AFK63_00210 nirD nirD 41749 42075 - nitrite reductase involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+%3B bounds to NirB%2C the cytoplasmic subunit%2C whose expression is induced at high nitrate concentrations gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00210 AFK63_RS00215 AFK63_00215 AFK63_RS00215 42072 44618 - nitrite reductase gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00215 AFK63_RS00220 AFK63_00220 AFK63_RS00220 44942 46129 - transporter gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00220 AFK63_RS00225 AFK63_00225 AFK63_RS00225 46405 46977 + peptidyl-prolyl cis-trans isomerase gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00225 AFK63_RS00230 AFK63_00230 AFK63_RS00230 47245 47847 + cell filamentation protein Fic gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00230 AFK63_RS00235 AFK63_00235 AFK63_RS00235 47878 48441 + anthranilate synthase component II TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00235 AFK63_RS00240 AFK63_00240 argD argD 48528 49748 + acetylornithine aminotransferase DapATase%3B bifunctional enzyme that functions in arginine and lysine biosynthetic pathways%3B catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2%2C6-diaminoheptanedioate gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00240 AFK63_RS00245 AFK63_00245 AFK63_RS00245 49749 51833 - membrane protein gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00245 AFK63_RS00250 AFK63_00250 AFK63_RS00250 51899 52531 - cAMP-activated global transcriptional regulator CRP cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00250 AFK63_RS00255 AFK63_00255 AFK63_RS00255 52840 53244 + hypothetical protein gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00255 AFK63_RS00260 AFK63_00260 AFK63_RS00260 53306 54175 - phosphoribulokinase gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00260 AFK63_RS00265 AFK63_00265 AFK63_RS00265 54224 54442 - hypothetical protein gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00265 AFK63_RS00270 AFK63_00270 AFK63_RS00270 54443 55459 - hydrolase gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00270 AFK63_RS00275 AFK63_00275 AFK63_RS00275 55534 56253 - NUDIX hydrolase gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00275 AFK63_RS00280 AFK63_00280 AFK63_RS00280 56449 57306 + ribose-phosphate pyrophosphokinase gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00280 AFK63_RS00285 AFK63_00285 AFK63_RS00285 57318 58808 + nicotinate phosphoribosyltransferase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00285 AFK63_RS00290 AFK63_00290 AFK63_RS00290 58898 59872 - hypothetical protein gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00290 AFK63_RS00295 AFK63_00295 AFK63_RS00295 59932 61053 - Tellurite resistance protein gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00295 AFK63_RS00300 AFK63_00300 AFK63_RS00300 61465 63375 - ABC transporter ATP-binding protein gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00300 AFK63_RS00305 AFK63_00305 AFK63_RS00305 63503 64054 + potassium transporter KefG required for KefB activity gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00305 AFK63_RS00310 AFK63_00310 AFK63_RS00310 64054 65859 + potassium transporter KefB involved in potassium efflux gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00310 AFK63_RS00315 AFK63_00315 AFK63_RS00315 65870 66070 + hypothetical protein gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00315 AFK63_RS00320 AFK63_00320 AFK63_RS00320 66165 66749 + peptidylprolyl isomerase rotamase gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00320 AFK63_RS00325 AFK63_00325 AFK63_RS00325 66804 67022 - protein slyX required for phi X174 lysis gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00325 AFK63_RS00330 AFK63_00330 AFK63_RS00330 67238 68065 + peptidylprolyl isomerase rotamase gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00330 AFK63_RS00335 AFK63_00335 AFK63_RS00335 68241 68963 + hypothetical protein gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00335 AFK63_RS00340 AFK63_00340 AFK63_RS00340 68963 69349 + sulfur transfer complex subunit TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00340 AFK63_RS00345 AFK63_00345 AFK63_RS00345 69349 69708 + sulfur relay protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur transfer that results in thiouridation to U34 position in some tRNAs gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00345 AFK63_RS00350 AFK63_00350 AFK63_RS00350 69717 70004 + sulfur transfer complex subunit TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00350 AFK63_RS00355 AFK63_00355 AFK63_RS00355 70129 70503 + 30S ribosomal protein S12 gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00355 AFK63_RS00360 AFK63_00360 AFK63_RS00360 70599 71069 + 30S ribosomal protein S7 gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00360 AFK63_RS00365 AFK63_00365 fusA fusA 71167 73281 + elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00365 AFK63_RS00370 AFK63_00370 tuf tuf 73349 74533 + elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00370 AFK63_RS00375 AFK63_00375 AFK63_RS00375 74632 74775 - ferredoxin gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00375 AFK63_RS00380 AFK63_00380 AFK63_RS00380 74970 75446 + bacterioferritin iron storage protein gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00380 AFK63_RS00385 AFK63_00385 AFK63_RS00385 75450 75917 - peptidase A24 gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00385 AFK63_RS00390 AFK63_00390 rpsJ rpsJ 76297 76608 + 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00390 AFK63_RS00395 AFK63_00395 AFK63_RS00395 76641 77270 + 50S ribosomal protein L3 gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00395 AFK63_RS00400 AFK63_00400 rplD rplD 77281 77886 + 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00400 AFK63_RS00405 AFK63_00405 rplW rplW 77883 78185 + 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00405 AFK63_RS00410 AFK63_00410 AFK63_RS00410 78203 79024 + 50S ribosomal protein L2 gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00410 AFK63_RS00415 AFK63_00415 AFK63_RS00415 79041 79319 + 30S ribosomal protein S19 gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00415 AFK63_RS00420 AFK63_00420 AFK63_RS00420 79333 79665 + 50S ribosomal protein L22 gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00420 AFK63_RS00425 AFK63_00425 AFK63_RS00425 79683 80384 + 30S ribosomal protein S3 gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00425 AFK63_RS00430 AFK63_00430 AFK63_RS00430 80397 80807 + 50S ribosomal protein L16 gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00430 AFK63_RS00435 AFK63_00435 AFK63_RS00435 80807 80998 + 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00435 AFK63_RS00440 AFK63_00440 AFK63_RS00440 80998 81252 + 30S ribosomal protein S17 gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00440 AFK63_RS00445 AFK63_00445 AFK63_RS00445 81419 81790 + 50S ribosomal protein L14 gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00445 AFK63_RS00450 AFK63_00450 rplX rplX 81801 82115 + 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00450 AFK63_RS00455 AFK63_00455 AFK63_RS00455 82130 82669 + 50S ribosomal protein L5 gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00455 AFK63_RS00460 AFK63_00460 rpsN rpsN 82684 82989 + 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00460 AFK63_RS00465 AFK63_00465 AFK63_RS00465 83023 83415 + 30S ribosomal protein S8 gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00465 AFK63_RS00470 AFK63_00470 AFK63_RS00470 83428 83961 + 50S ribosomal protein L6 gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00470 AFK63_RS00475 AFK63_00475 AFK63_RS00475 83971 84324 + 50S ribosomal protein L18 gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00475 AFK63_RS00480 AFK63_00480 AFK63_RS00480 84339 84839 + 30S ribosomal protein S5 gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00480 AFK63_RS00485 AFK63_00485 rpmD rpmD 84846 85025 + 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00485 AFK63_RS00490 AFK63_00490 AFK63_RS00490 85029 85463 + 50S ribosomal protein L15 gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00490 AFK63_RS00495 AFK63_00495 secY secY 85471 86802 + preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00495 AFK63_RS00500 AFK63_00500 AFK63_RS00500 87096 87452 + 30S ribosomal protein S13 gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00500 AFK63_RS00505 AFK63_00505 AFK63_RS00505 87469 87858 + 30S ribosomal protein S11 gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00505 AFK63_RS00510 AFK63_00510 AFK63_RS00510 87890 88510 + 30S ribosomal protein S4 gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00510 AFK63_RS00515 AFK63_00515 AFK63_RS00515 88536 89525 + DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00515 AFK63_RS00520 AFK63_00520 rplQ rplQ 89566 89952 + 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00520 AFK63_RS00525 AFK63_00525 AFK63_RS00525 90063 90428 + hypothetical protein gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00525 AFK63_RS00530 AFK63_00530 zntR zntR 90431 90856 + zinc-responsive transcriptional regulator mediates expression of the zinc export protein ZntA in response to high levels of zinc%3B member of MerR family of transcriptional regulators gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00530 AFK63_RS00535 AFK63_00535 AFK63_RS00535 90909 91169 + ribosome rescue factor A gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00535 AFK63_RS00540 AFK63_00540 mscL mscL 91123 91527 - large-conductance mechanosensitive channel forms homopentamer%3B channel that opens in response to pressure or hypoosmotic shock gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00540 AFK63_RS00545 AFK63_00545 trkA trkA 91681 93057 - potassium transporter peripheral membrane component involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00545 AFK63_RS00550 AFK63_00550 AFK63_RS00550 93098 94387 - 16S rRNA methyltransferase catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA%3B SAM-dependent methyltransferase gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00550 AFK63_RS00555 AFK63_00555 fmt fmt 94456 95403 - methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00555 AFK63_RS00560 AFK63_00560 AFK63_RS00560 95422 95937 - peptide deformylase gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00560 AFK63_RS00565 AFK63_00565 AFK63_RS00565 96067 97179 + DNA processing protein DprA gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00565 AFK63_RS00570 AFK63_00570 AFK63_RS00570 97151 97624 + hypothetical protein gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00570 AFK63_RS00575 AFK63_00575 AFK63_RS00575 97669 97986 - hypothetical protein gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00575 AFK63_RS00580 AFK63_00580 AFK63_RS00580 98195 98767 + tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00580 AFK63_RS00585 AFK63_00585 AFK63_RS00585 98771 99589 + shikimate dehydrogenase gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00585 AFK63_RS00590 AFK63_00590 AFK63_RS00590 99586 99843 + hypothetical protein gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00590 AFK63_RS00595 AFK63_00595 AFK63_RS00595 99819 100373 - hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00595 AFK63_RS00600 AFK63_00600 AFK63_RS00600 100401 100598 + hypothetical protein gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00600 AFK63_RS00605 AFK63_00605 AFK63_RS00605 100849 102402 + 16S ribosomal RNA rRNA gene120 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00605 AFK63_RS00610 AFK63_00610 AFK63_RS00610 102480 102554 + tRNA-Glu tRNA gene121 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00610 AFK63_RS00615 AFK63_00615 AFK63_RS00615 102748 105676 + 23S ribosomal RNA rRNA gene122 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00615 AFK63_RS00620 AFK63_00620 AFK63_RS00620 105754 105869 + 5S ribosomal RNA rRNA gene123 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00620 AFK63_RS00625 AFK63_00625 AFK63_RS00625 106425 107354 + homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00625 AFK63_RS00630 AFK63_00630 AFK63_RS00630 107627 109225 + malate synthase Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00630 AFK63_RS00635 AFK63_00635 AFK63_RS00635 109257 110564 + isocitrate lyase gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00635 AFK63_RS00640 AFK63_00640 aceK aceK 110711 112549 + isocitrate dehydrogenase catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity%3B unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00640 AFK63_RS00645 AFK63_00645 AFK63_RS00645 112592 113428 - IclR family transcriptional regulator regulates the glyoxylate bypass operon (aceBAK)%2C which encodes isocitrate lyase%2C malate synthase and isocitrate dehydrogenase kinase/phosphorylase gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00645 AFK63_RS00650 AFK63_00650 metH metH 113626 117309 + B12-dependent methionine synthase one of two methionine synthases in Escherichia coli%3B MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine%3B requires zinc for activity gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00650 AFK63_RS00655 AFK63_00655 AFK63_RS00655 117843 119474 + membrane protein gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00655 AFK63_RS00660 AFK63_00660 AFK63_RS00660 119566 119838 - hypothetical protein gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00660 AFK63_RS00665 AFK63_00665 AFK63_RS00665 119929 120876 - bile acid:sodium symporter gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00665 AFK63_RS00670 AFK63_00670 AFK63_RS00670 121059 122651 - transcriptional regulator sigma 54-dependent%3B regulates genes involved in forming a 2'%2C3'-cyclic phosphodiester on RNA gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00670 AFK63_RS00675 AFK63_00675 AFK63_RS00675 123127 124260 + SPFH domain / Band 7 family protein gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00675 AFK63_RS00680 AFK63_00680 AFK63_RS00680 124263 125486 + RNA ligase gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00680 AFK63_RS00685 AFK63_00685 AFK63_RS00685 125503 126288 + nucleotidyltransferase gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00685 AFK63_RS00690 AFK63_00690 AFK63_RS00690 126311 127663 - aspartate kinase catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B functions in amino acid biosynthesis%3B lysine sensitive gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00690 AFK63_RS00695 AFK63_RS00695 AFK63_RS00695 127693 128106 + hypothetical protein gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00695 AFK63_RS00700 AFK63_00700 pgi pgi 128802 130451 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00700 AFK63_RS00705 AFK63_00705 AFK63_RS00705 130832 131080 + hypothetical protein gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00705 AFK63_RS00710 AFK63_00710 AFK63_RS00710 131149 131784 + hypothetical protein gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00710 AFK63_RS00715 AFK63_00715 AFK63_RS00715 131784 132518 + hypothetical protein gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00715 AFK63_RS00720 AFK63_00720 AFK63_RS00720 132518 134614 + membrane protein gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00720 AFK63_RS00725 AFK63_00725 AFK63_RS00725 134850 135317 - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00725 AFK63_RS00730 AFK63_00730 AFK63_RS00730 135317 135958 - glutamate racemase gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00730 AFK63_RS00735 AFK63_00735 malG malG 136182 137072 - maltose transporter permease with MalKFE is involved in the transport of maltose into the cell gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00735 AFK63_RS00740 AFK63_00740 malF malF 137084 138625 - maltose transporter membrane protein with MalKGE is involved in maltose transport into the cell gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00740 AFK63_RS00745 AFK63_00745 malE malE 138788 139978 - sugar ABC transporter substrate-binding protein functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00745 AFK63_RS00750 AFK63_00750 AFK63_RS00750 140348 141457 + Maltose/maltodextrin transport ATP-binding protein MalK with malEFG is involved in import of maltose/maltodextrin gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00750 AFK63_RS00755 AFK63_00755 lamB lamB 141502 142791 + maltoporin porin involved in the transport of maltose and maltodextrins gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00755 AFK63_RS00760 AFK63_00760 AFK63_RS00760 142908 143879 + maltose-binding protein gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00760 AFK63_RS00765 AFK63_00765 ubiC ubiC 144062 144571 + chorismate--pyruvate lyase catalyzes the formation of 4-hydroxybenzoate from chorismate gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00765 AFK63_RS00770 AFK63_00770 ubiA ubiA 144571 145443 + 4-hydroxybenzoate polyprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00770 AFK63_RS00775 AFK63_00775 AFK63_RS00775 145491 147917 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00775 AFK63_RS00780 AFK63_00780 AFK63_RS00780 148050 148418 + diacylglycerol kinase catalyzes the phosphorylation of diacylglycerol to form diacylglycerol phosphate gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00780 AFK63_RS00785 AFK63_00785 AFK63_RS00785 148527 149135 + LexA repressor Represses a number of genes involved in the response to DNA damage gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00785 AFK63_RS00790 AFK63_00790 AFK63_RS00790 149258 150565 + MATE family efflux transporter gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00790 AFK63_RS00795 AFK63_00795 AFK63_RS00795 150777 150986 + hypothetical protein gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00795 AFK63_RS00800 AFK63_00800 AFK63_RS00800 151067 151582 - transcriptional regulator Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00800 AFK63_RS00805 AFK63_00805 AFK63_RS00805 151691 152197 + cupin gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00805 AFK63_RS00810 AFK63_00810 AFK63_RS00810 152344 153624 + conjugal transfer protein gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00810 AFK63_RS00815 AFK63_00815 AFK63_RS00815 153715 154710 + tRNA-dihydrouridine synthase A gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00815 AFK63_RS00820 AFK63_00820 pspG pspG 154842 155102 + hypothetical protein coordinately regulated along with pspA%3B PspF-dependent induction in response to secretin overexpression in Yersinia gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00820 AFK63_RS00825 AFK63_00825 AFK63_RS00825 155283 156266 - quinone oxidoreductase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00825 AFK63_RS00830 AFK63_00830 AFK63_RS00830 156387 157793 + DNA helicase unwinds double stranded DNA gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00830 AFK63_RS00835 AFK63_00835 alr alr 157967 159046 + alanine racemase converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00835 AFK63_RS00840 AFK63_00840 AFK63_RS00840 159306 160499 + aromatic amino acid aminotransferase catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00840 AFK63_RS00845 AFK63_00845 AFK63_RS00845 160932 162614 + hemolysin activator protein precursor gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00845 AFK63_RS00850 AFK63_00850 AFK63_RS00850 162742 163164 + hypothetical protein gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00850 AFK63_RS00855 AFK63_00855 AFK63_RS00855 163161 163514 + hypothetical protein gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00855 AFK63_RS00860 AFK63_00860 AFK63_RS00860 164024 165748 + hemolysin gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00860 AFK63_RS00865 AFK63_00865 AFK63_RS00865 166529 169357 - excinuclease ABC subunit A gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00865 AFK63_RS00870 AFK63_00870 AFK63_RS00870 169588 170130 + Single-stranded DNA-binding protein binds to single stranded DNA and PriA helcase facilitate replication restart gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00870 AFK63_RS00875 AFK63_00875 AFK63_RS00875 170558 171604 + diguanylate cyclase gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00875 AFK63_RS00880 AFK63_00880 AFK63_RS00880 171780 172124 + hypothetical protein gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00880 AFK63_RS00885 AFK63_00885 AFK63_RS00885 172180 172458 - membrane protein gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00885 AFK63_RS00890 AFK63_00890 AFK63_RS00890 173089 174648 + hypothetical protein gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00890 AFK63_RS00895 AFK63_00895 AFK63_RS00895 174636 174959 - transcriptional regulator regulates genes involved in response to oxidative stress gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00895 AFK63_RS00900 AFK63_00900 AFK63_RS00900 175046 175504 + transcriptional regulator gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00900 AFK63_RS00905 AFK63_00905 AFK63_RS00905 175582 176250 + glutathione S-transferase gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00905 AFK63_RS00910 AFK63_00910 AFK63_RS00910 176566 177915 + permease gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00910 AFK63_RS00915 AFK63_00915 AFK63_RS00915 178054 179700 + sodium:proton antiporter gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00915 AFK63_RS00920 AFK63_00920 AFK63_RS00920 179734 181029 - dehydrogenase gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00920 AFK63_RS00925 AFK63_00925 actP actP 181171 182820 - acetate permease member of the sodium:solute symporter family%3B cotranscribed with the acs gene which encodes acetyl coenzyme A synthase%3B mutations affect acetate uptake gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00925 AFK63_RS00930 AFK63_00930 AFK63_RS00930 182817 183128 - membrane protein gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00930 AFK63_RS00935 AFK63_00935 AFK63_RS00935 183225 185183 - acetyl-CoA synthetase Acs%3B catalyzes the conversion of acetate and CoA to acetyl-CoA gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00935 AFK63_RS00940 AFK63_00940 AFK63_RS00940 185608 186921 + glutamate:protein symporter gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00940 AFK63_RS00945 AFK63_00945 AFK63_RS00945 187181 187333 - Hok/gef cell toxic protein gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00945 AFK63_RS00950 AFK63_00950 AFK63_RS00950 187732 187884 - Hok/gef cell toxic protein gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00950 AFK63_RS00955 AFK63_00955 AFK63_RS00955 188432 190288 + histidine kinase gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00955 AFK63_RS00960 AFK63_00960 AFK63_RS00960 190288 192603 + hypothetical protein gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00960 AFK63_RS00965 AFK63_00965 AFK63_RS00965 192710 193051 + membrane protein gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00965 AFK63_RS00970 AFK63_00970 phnH phnH 193048 193644 - carbon-phosphorus lyase complex subunit gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00970 AFK63_RS00975 AFK63_00975 AFK63_RS00975 194358 194693 - hypothetical protein gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00975 AFK63_RS00980 AFK63_00980 AFK63_RS00980 195257 197620 + vimentin gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00980 AFK63_RS00985 AFK63_00985 AFK63_RS00985 197626 198477 + methyl-accepting chemotaxis protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00985 AFK63_RS00990 AFK63_00990 AFK63_RS00990 198510 199505 - 2-keto-3-deoxygluconate permease transports degraded pectin products into the bacterial cell gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00990 AFK63_RS00995 AFK63_00995 AFK63_RS00995 199905 200741 + 5-keto-4-deoxyuronate isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase%3B catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS00995 AFK63_RS01000 AFK63_01000 AFK63_RS01000 200801 201667 - S-transferase YghU%3B B2989%3B one of eight putative glutathione transferase proteins from E. coli gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01000 AFK63_RS01005 AFK63_01005 AFK63_RS01005 201777 202739 - nickel transporter gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01005 AFK63_RS01010 AFK63_01010 AFK63_RS01010 202778 203005 + hypothetical protein gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01010 AFK63_RS01015 AFK63_01015 AFK63_RS01015 203248 203323 - tRNA-Phe tRNA gene202 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01015 AFK63_RS01020 AFK63_01020 AFK63_RS01020 203438 204013 - transcriptional regulator gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01020 AFK63_RS01025 AFK63_01025 dipZ dipZ 204064 205809 - thiol:disulfide interchange protein precursor two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm%3B DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01025 AFK63_RS01030 AFK63_01030 AFK63_RS01030 205785 206132 - cation tolerance protein CutA copper binding protein required for copper tolerance%3B involved in resistance toward heavy metals gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01030 AFK63_RS01035 AFK63_01035 AFK63_RS01035 206258 207559 - C4-dicarboxylate transporter functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to dcuB gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01035 AFK63_RS01040 AFK63_01040 aspA aspA 207672 209108 - aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01040 AFK63_RS01045 AFK63_01045 fxsA fxsA 209446 209922 + phage T7 F exclusion suppressor FxsA F exclusion of bacteriophage T7%3B overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7%3B interacts with the F plasmid-encoded PifA protein%3B inner membrane protein gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01045 AFK63_RS01050 AFK63_01050 groES groES 210058 210351 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01050 AFK63_RS01055 AFK63_01055 groEL groEL 210400 212043 + molecular chaperone GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01055 AFK63_RS01060 AFK63_01060 AFK63_RS01060 212195 212548 + membrane protein gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01060 AFK63_RS01065 AFK63_01065 AFK63_RS01065 212693 213721 - EF-P beta-lysylation protein EpmB gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01065 AFK63_RS01070 AFK63_01070 AFK63_RS01070 213762 214328 + elongation factor P gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01070 AFK63_RS01075 AFK63_01075 AFK63_RS01075 214618 214764 + entericidin B gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01075 AFK63_RS01080 AFK63_01080 AFK63_RS01080 214802 215407 - transcriptional regulator gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01080 AFK63_RS01085 AFK63_01085 AFK63_RS01085 215686 216003 + multidrug transporter member of the SMR family of proton-dependent drug efflux transporters%3B quaternary ammonium compound efflux pump%3B confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01085 AFK63_RS01090 AFK63_01090 AFK63_RS01090 216000 216533 - membrane protein lipocalin%3B globomycin-sensitive outer membrane lipoprotein gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01090 AFK63_RS01095 AFK63_01095 AFK63_RS01095 216656 217015 - fumarate reductase gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01095 AFK63_RS01100 AFK63_01100 AFK63_RS01100 217026 217421 - fumarate reductase part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01100 AFK63_RS01105 AFK63_01105 AFK63_RS01105 217421 218167 - fumarate reductase part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01105 AFK63_RS01110 AFK63_01110 AFK63_RS01110 218160 219950 - fumarate reductase part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01110 AFK63_RS01115 AFK63_01115 AFK63_RS01115 220253 221230 + poxB regulator PoxA poxA%3B regulates pyruvate oxidase poxB gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01115 AFK63_RS01120 AFK63_01120 AFK63_RS01120 221378 224710 - mechanosensitive channel protein gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01120 AFK63_RS01125 AFK63_01125 psd psd 224728 225690 - phosphatidylserine decarboxylase catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01125 AFK63_RS01130 AFK63_01130 AFK63_RS01130 225787 226833 - GTPase RsgA EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01130 AFK63_RS01135 AFK63_01135 AFK63_RS01135 226946 227491 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01135 AFK63_RS01140 AFK63_01140 AFK63_RS01140 227659 227734 + tRNA-Gly tRNA gene227 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01140 AFK63_RS01145 AFK63_01145 AFK63_RS01145 227769 227844 + tRNA-Gly tRNA gene228 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01145 AFK63_RS01150 AFK63_01150 AFK63_RS01150 227878 227953 + tRNA-Gly tRNA gene229 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01150 AFK63_RS01155 AFK63_01155 AFK63_RS01155 228223 229362 - epoxyqueuosine reductase gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01155 AFK63_RS01160 AFK63_01160 AFK63_RS01160 229376 230884 + carbohydrate kinase gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01160 AFK63_RS01165 AFK63_01165 AFK63_RS01165 230881 231339 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE needed for nucleoid integrity%3B possibly involved in cell wall synthesis gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01165 AFK63_RS01170 AFK63_01170 AFK63_RS01170 231356 232690 + N-acetylmuramoyl-L-alanine amidase gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01170 AFK63_RS01175 AFK63_01175 AFK63_RS01175 232700 234595 + DNA mismatch repair protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01175 AFK63_RS01180 AFK63_01180 miaA miaA 234588 235538 + tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01180 AFK63_RS01185 AFK63_01185 hfq hfq 235639 235947 + RNA chaperone Hfq HF-I%2C host factor for RNA phage Q beta replication gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01185 AFK63_RS01190 AFK63_01190 AFK63_RS01190 236021 237301 + GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01190 AFK63_RS01195 AFK63_01195 AFK63_RS01195 237473 238717 + cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01195 AFK63_RS01200 AFK63_01200 AFK63_RS01200 238720 239724 + cell division protein FtsH with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01200 AFK63_RS01205 AFK63_01205 AFK63_RS01205 239788 239985 + hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01205 AFK63_RS01210 AFK63_01210 AFK63_RS01210 240089 241387 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01210 AFK63_RS01215 AFK63_01215 AFK63_RS01215 241542 241967 + transcriptional regulator negatively regulates the transcription of genes upregulated by nitrosative stress gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01215 AFK63_RS01220 AFK63_01220 AFK63_RS01220 242004 244433 + exoribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01220 AFK63_RS01225 AFK63_01225 AFK63_RS01225 244529 245260 + 23S rRNA methyltransferase Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01225 AFK63_RS01230 AFK63_01230 AFK63_RS01230 245469 245846 + membrane protein gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01230 AFK63_RS01235 AFK63_01235 AFK63_RS01235 245869 246519 + hypothetical protein gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01235 AFK63_RS01240 AFK63_01240 AFK63_RS01240 246520 247707 + hypothetical protein gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01240 AFK63_RS01245 AFK63_01245 AFK63_RS01245 247797 249431 + isovaleryl-CoA dehydrogenase catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01245 AFK63_RS01250 AFK63_01250 AFK63_RS01250 249432 251363 - chemotaxis protein gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01250 AFK63_RS01255 AFK63_01255 AFK63_RS01255 251512 251787 - membrane protein gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01255 AFK63_RS01260 AFK63_01260 AFK63_RS01260 251923 252231 - biofilm stress and motility protein A in Escherichia coli%2C mutation of this gene affects biofilm maturation%2C stress response%2C and motility gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01260 AFK63_RS01265 AFK63_01265 AFK63_RS01265 252435 253163 + esterase YjfP%3B esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro%3B unknown function and substrate in vivo gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01265 AFK63_RS01270 AFK63_01270 rpsF rpsF 253341 253736 + 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01270 AFK63_RS01275 AFK63_01275 AFK63_RS01275 253742 254056 + primosomal replication protein n binds single-stranded DNA at the primosome assembly site gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01275 AFK63_RS01280 AFK63_01280 rpsR rpsR 254061 254288 + 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01280 AFK63_RS01285 AFK63_01285 rplI rplI 254330 254779 + 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01285 AFK63_RS01290 AFK63_01290 AFK63_RS01290 254852 255430 - opacity-associated protein OapA gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01290 AFK63_RS01295 AFK63_01295 AFK63_RS01295 255622 256242 + FKBP-type peptidyl-prolyl cis-trans isomerase FKBP-type%3B rotamase%3B catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01295 AFK63_RS01300 AFK63_01300 AFK63_RS01300 256531 257943 + amino acid permease gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01300 AFK63_RS01305 AFK63_01305 AFK63_RS01305 258011 258676 - iron-sulfur cluster repair di-iron protein Involved in anaerobic NO protection and iron metabolism gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01305 AFK63_RS01310 AFK63_01310 AFK63_RS01310 258920 260593 + chemotaxis protein serine sensor receptor gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01310 AFK63_RS01315 AFK63_01315 AFK63_RS01315 260625 261593 - membrane protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01315 AFK63_RS01320 AFK63_01320 AFK63_RS01320 261673 262254 - hypothetical protein gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01320 AFK63_RS01325 AFK63_01325 AFK63_RS01325 262314 263138 - AraC family transcriptional regulator gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01325 AFK63_RS01330 AFK63_01330 AFK63_RS01330 263224 263595 - hypothetical protein gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01330 AFK63_RS01335 AFK63_01335 AFK63_RS01335 263704 264558 - quinone oxidoreductase gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01335 AFK63_RS01340 AFK63_01340 AFK63_RS01340 264648 265028 + HxlR family transcriptional regulator gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01340 AFK63_RS01345 AFK63_01345 cpdB cpdB 265149 267092 - 2'%2C 3'-cyclic nucleotide 2'-phosphodiesterase periplasmic enzyme%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01345 AFK63_RS01350 AFK63_01350 AFK63_RS01350 267312 268055 + adenosine-3'(2')%2C5'-bisphosphate nucleotidase catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01350 AFK63_RS01355 AFK63_01355 AFK63_RS01355 268045 268602 - hypothetical protein gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01355 AFK63_RS01360 AFK63_01360 AFK63_RS01360 268931 269137 + hypothetical protein gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01360 AFK63_RS01365 AFK63_01365 AFK63_RS01365 269202 270533 - membrane protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01365 AFK63_RS01370 AFK63_01370 AFK63_RS01370 270732 272147 - periplasmic or exported protein gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01370 AFK63_RS01375 AFK63_01375 AFK63_RS01375 272253 272891 - methionine sulfoxide reductase A this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form%3B provides protection against oxidative stress gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01375 AFK63_RS01380 AFK63_01380 AFK63_RS01380 273116 274849 + membrane protein gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01380 AFK63_RS01385 AFK63_01385 AFK63_RS01385 274846 278622 + translocation and assembly module TamB gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01385 AFK63_RS01390 AFK63_01390 AFK63_RS01390 278625 278960 + gamma-glutamylcyclotransferase gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01390 AFK63_RS01395 AFK63_01395 AFK63_RS01395 279378 279911 + fimbria A protein gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01395 AFK63_RS01400 AFK63_01400 AFK63_RS01400 280099 280536 + fimbrial protein gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01400 AFK63_RS01405 AFK63_01405 AFK63_RS01405 280692 283106 + fimbrial assembly protein gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01405 AFK63_RS01410 AFK63_01410 AFK63_RS01410 283149 283907 + molecular chaperone gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01410 AFK63_RS01415 AFK63_01415 AFK63_RS01415 283929 284504 + fimbrial protein gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01415 AFK63_RS01420 AFK63_01420 AFK63_RS01420 284581 285033 + fimbrial protein gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01420 AFK63_RS01425 AFK63_01425 AFK63_RS01425 285065 285649 + MrfF gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01425 AFK63_RS01430 AFK63_01430 AFK63_RS01430 285661 286176 + fimbrial protein gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01430 AFK63_RS01435 AFK63_01435 AFK63_RS01435 287480 289090 + lipid A core--O-antigen ligase gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01435 AFK63_RS01440 AFK63_01440 AFK63_RS01440 289257 290852 + chemotaxis protein gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01440 AFK63_RS01445 AFK63_01445 AFK63_RS01445 290901 291428 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01445 AFK63_RS01450 AFK63_01450 AFK63_RS01450 291829 292785 + sugar ABC transporter substrate-binding protein gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01450 AFK63_RS01455 AFK63_01455 AFK63_RS01455 292974 294476 + sugar ABC transporter ATP-binding protein gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01455 AFK63_RS01460 AFK63_01460 AFK63_RS01460 294490 295512 + sugar ABC transporter permease gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01460 AFK63_RS01465 AFK63_01465 AFK63_RS01465 295499 296488 + ABC transporter permease membrane component of a putative sugar ABC transporter system gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01465 AFK63_RS01470 AFK63_01470 AFK63_RS01470 296599 298164 + chemotaxis protein gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01470 AFK63_RS01475 AFK63_01475 AFK63_RS01475 298377 299375 - fructose 1%2C6-bisphosphatase catalyzes the formation of D-fructose 6-phosphate from fructose-1%2C6-bisphosphate gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01475 AFK63_RS01480 AFK63_01480 AFK63_RS01480 299551 300930 + UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase ligates L-alanyl-gamma-D-glutamyl-meso-diaminopimelate to UDP-N-acetylmuramic acid for reincorporation into peptidoglycan gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01480 AFK63_RS01485 AFK63_01485 AFK63_RS01485 300988 302196 - thioredoxin gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01485 AFK63_RS01490 AFK63_01490 AFK63_RS01490 302521 303072 - hypothetical protein gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01490 AFK63_RS01495 AFK63_01495 pmbA pmbA 303180 304532 + peptidase PMbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01495 AFK63_RS01500 AFK63_01500 AFK63_RS01500 304590 304976 + cytochrome b562 electron transport protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01500 AFK63_RS01505 AFK63_01505 AFK63_RS01505 305298 305621 + glycine dehydrogenase gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01505 AFK63_RS01510 AFK63_01510 AFK63_RS01510 305638 306000 + hypothetical protein gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01510 AFK63_RS01515 AFK63_01515 AFK63_RS01515 306004 306306 + hypothetical protein gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01515 AFK63_RS01520 AFK63_01520 AFK63_RS01520 306329 307105 + membrane protein gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01520 AFK63_RS01525 AFK63_01525 AFK63_RS01525 307116 307760 + membrane protein gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01525 AFK63_RS01530 AFK63_01530 AFK63_RS01530 307800 308933 + dihydroorotase Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01530 AFK63_RS01535 AFK63_01535 AFK63_RS01535 308917 310035 + L-seryl-tRNA selenium transferase gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01535 AFK63_RS01540 AFK63_01540 AFK63_RS01540 310032 310772 + 2-dehydro-3-deoxyphosphooctonate aldolase gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01540 AFK63_RS01545 AFK63_01545 AFK63_RS01545 310884 312794 + transcription antiterminator BglG gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01545 AFK63_RS01550 AFK63_01550 AFK63_RS01550 312824 313288 - anaerobic ribonucleoside-triphosphate reductase activating protein activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01550 AFK63_RS01555 AFK63_01555 AFK63_RS01555 313468 315603 - ribonucleoside-triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01555 AFK63_RS01560 AFK63_01560 AFK63_RS01560 315901 316782 - LysR family transcriptional regulator gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01560 AFK63_RS01565 AFK63_01565 AFK63_RS01565 316885 317415 + oxidoreductase gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01565 AFK63_RS01570 AFK63_01570 AFK63_RS01570 317440 319095 - trehalose-6-phosphate hydrolase gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01570 AFK63_RS01575 AFK63_01575 AFK63_RS01575 319156 320574 - PTS trehalose(maltose) transporter subunits IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01575 AFK63_RS01580 AFK63_01580 treR treR 320711 321658 - trehalose repressor regulates genes involved in trehalose metabolism%3B binds the intermediate trehalose-6-phosphate%3B binds a dimer%3B regulates treBC operon gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01580 AFK63_RS01585 AFK63_01585 AFK63_RS01585 321653 321853 + hypothetical protein gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01585 AFK63_RS01590 AFK63_01590 AFK63_RS01590 321899 322525 - transcriptional regulator gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01590 AFK63_RS01595 AFK63_01595 AFK63_RS01595 322718 323353 + glutaredoxin gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01595 AFK63_RS01600 AFK63_01600 AFK63_RS01600 323408 323710 + antibiotic biosynthesis monooxygenase gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01600 AFK63_RS01605 AFK63_01605 AFK63_RS01605 323777 324286 - hypothetical protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01605 AFK63_RS01610 AFK63_01610 dkgA dkgA 324363 325190 - 2%2C5-diketo-D-gluconic acid reductase methylglyoxal reductase/beta-keto ester reductase%3B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid%3B also catalyzes the reduction of methylglyoxal%2C ethyl-2-methylacetoacetate and ethyl-acetoacetate gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01610 AFK63_RS01615 AFK63_01615 AFK63_RS01615 325296 326459 - aldehyde reductase gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01615 AFK63_RS01620 AFK63_01620 AFK63_RS01620 326452 326643 + hypothetical protein gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01620 AFK63_RS01625 AFK63_01625 AFK63_RS01625 326647 327540 + AraC family transcriptional regulator gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01625 AFK63_RS01630 AFK63_01630 AFK63_RS01630 327569 328222 - membrane protein gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01630 AFK63_RS01635 AFK63_01635 AFK63_RS01635 328341 329528 - cystathionine beta-lyase catalyzes the formation of L-homocysteine from cystathionine gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01635 AFK63_RS01640 AFK63_01640 AFK63_RS01640 329777 330511 + biopolymer transporter ExbB membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01640 AFK63_RS01645 AFK63_01645 AFK63_RS01645 330518 330943 + biopolymer transporter ExbD membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01645 AFK63_RS01650 AFK63_01650 AFK63_RS01650 331017 331913 - oxidoreductase gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01650 AFK63_RS01655 AFK63_01655 AFK63_RS01655 332085 332825 + DeoR family transcriptional regulator gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01655 AFK63_RS01660 AFK63_01660 AFK63_RS01660 332811 333230 - hypothetical protein gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01660 AFK63_RS01665 AFK63_01665 AFK63_RS01665 333236 333637 - hypothetical protein gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01665 AFK63_RS01670 AFK63_01670 AFK63_RS01670 333743 334243 + RNA helicase gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01670 AFK63_RS01675 AFK63_01675 AFK63_RS01675 334365 334862 + hypothetical protein gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01675 AFK63_RS01680 AFK63_01680 AFK63_RS01680 334929 335969 - glyceraldehyde 3-phosphate reductase gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01680 AFK63_RS01685 AFK63_01685 AFK63_RS01685 336167 337297 + mechanosensitive ion channel protein MscS gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01685 AFK63_RS01690 AFK63_01690 AFK63_RS01690 337394 338773 - maltoporin gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01690 AFK63_RS01695 AFK63_01695 AFK63_RS01695 338922 339227 - molecular chaperone TorD gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01695 AFK63_RS01700 AFK63_01700 AFK63_RS01700 339364 340689 - cytochrome C biogenesis protein CcmF gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01700 AFK63_RS01705 AFK63_01705 AFK63_RS01705 340706 341020 - PTS lactose transporter subunit IIB gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01705 AFK63_RS01710 AFK63_01710 AFK63_RS01710 341311 342264 + LacI family transcriptional regulator gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01710 AFK63_RS01715 AFK63_01715 AFK63_RS01715 342306 342923 - hypothetical protein gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01715 AFK63_RS01720 AFK63_01720 AFK63_RS01720 343192 346311 - transporter gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01720 AFK63_RS01725 AFK63_01725 AFK63_RS01725 346506 347345 + esterase gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01725 AFK63_RS01730 AFK63_01730 AFK63_RS01730 347689 347764 - tRNA-Phe tRNA gene345 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01730 AFK63_RS01735 AFK63_01735 AFK63_RS01735 347877 348596 - membrane protein gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01735 AFK63_RS01740 AFK63_01740 AFK63_RS01740 349140 351278 + ornithine decarboxylase gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01740 AFK63_RS01745 AFK63_01745 dpiA dpiA 351383 352081 - transcriptional regulator regulates the expression of citrate fermentation genes gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01745 AFK63_RS01750 AFK63_01750 AFK63_RS01750 352071 353705 - histidine kinase gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01750 AFK63_RS01755 AFK63_01755 AFK63_RS01755 354043 355407 + malate permease gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01755 AFK63_RS01760 AFK63_01760 AFK63_RS01760 355426 356289 + 5-oxopent-3-ene-1%2C2%2C5-tricarboxylate decarboxylase gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01760 AFK63_RS01765 AFK63_01765 AFK63_RS01765 356308 357339 + [citrate (pro-3S)-lyase] ligase gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01765 AFK63_RS01770 AFK63_01770 AFK63_RS01770 357365 357658 + citrate lyase subunit gamma acyl carrier protein%3B with CitE and CitF catalyzes the formation of oxaloacetate from citrate gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01770 AFK63_RS01775 AFK63_01775 AFK63_RS01775 357655 358530 + citrate lyase subunit beta citryl-ACP lyase%3B catalyzes the formation of acetate and oxaloacetate from citrate gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01775 AFK63_RS01780 AFK63_01780 AFK63_RS01780 358541 360058 + citrate lyase subunit alpha citrate-ACP transferase%2C the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01780 AFK63_RS01785 AFK63_01785 AFK63_RS01785 360062 360601 + apo-citrate lyase phosphoribosyl-dephospho-CoA transferase gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01785 AFK63_RS01790 AFK63_01790 AFK63_RS01790 360579 361421 + 2-(5'-triphosphoribosyl)-3'-dephospho CoA synthase gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01790 AFK63_RS01795 AFK63_01795 mltC mltC 361574 362656 - murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01795 AFK63_RS01800 AFK63_01800 AFK63_RS01800 362701 362976 - oxidative damage protection protein protects iron-sulfur proteins against oxidative damage gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01800 AFK63_RS01805 AFK63_01805 AFK63_RS01805 362979 364064 - A/G-specific adenine glycosylase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01805 AFK63_RS01810 AFK63_01810 trmB trmB 364217 364936 + tRNA (guanine-N7)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01810 AFK63_RS01815 AFK63_01815 AFK63_RS01815 364936 365262 + hypothetical protein gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01815 AFK63_RS01820 AFK63_01820 AFK63_RS01820 365314 366030 + hypothetical protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01820 AFK63_RS01825 AFK63_01825 AFK63_RS01825 366178 366558 + hypothetical protein gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01825 AFK63_RS01830 AFK63_01830 AFK63_RS01830 366734 366922 + toxin HicA gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01830 AFK63_RS01835 AFK63_01835 AFK63_RS01835 366939 367376 + CopG family transcriptional regulator gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01835 AFK63_RS01840 AFK63_01840 AFK63_RS01840 367436 368404 - GTP-binding protein gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01840 AFK63_RS01845 AFK63_01845 AFK63_RS01845 368423 368626 - hypothetical protein gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01845 AFK63_RS01850 AFK63_01850 AFK63_RS01850 368745 370898 - carbon starvation protein A gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01850 AFK63_RS01855 AFK63_01855 AFK63_RS01855 371892 373841 + methyl-accepting chemotaxis protein I gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01855 AFK63_RS01860 AFK63_01860 AFK63_RS01860 374018 374551 + beta-carotene hydroxylase gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01860 AFK63_RS01865 AFK63_01865 AFK63_RS01865 374448 375419 - phytoene synthase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01865 AFK63_RS01870 AFK63_01870 AFK63_RS01870 375416 376894 - phytoene dehydrogenase gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01870 AFK63_RS01875 AFK63_01875 AFK63_RS01875 376887 378062 - lycopene cyclase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01875 AFK63_RS01880 AFK63_01880 AFK63_RS01880 378059 379333 - Zeaxanthin glucosyltransferase gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01880 AFK63_RS01885 AFK63_01885 AFK63_RS01885 379330 380373 - isopentenyl pyrophosphate isomerase catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01885 AFK63_RS01890 AFK63_01890 AFK63_RS01890 380419 381324 - geranylgeranyl pyrophosphate synthase gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01890 AFK63_RS01895 AFK63_01895 AFK63_RS01895 381583 382131 - hypothetical protein gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01895 AFK63_RS01900 AFK63_01905 AFK63_RS01900 382651 382726 - tRNA-Met tRNA gene379 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01900 AFK63_RS01905 AFK63_01910 AFK63_RS01905 382852 383358 + formamidopyrimidine-DNA glycosylase gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01905 AFK63_RS01910 AFK63_01915 AFK63_RS01910 383405 383824 - hypothetical protein gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01910 AFK63_RS01915 AFK63_01920 AFK63_RS01915 384071 385915 - RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01915 AFK63_RS01920 AFK63_01925 dnaG dnaG 386153 387898 - DNA primase synthesizes RNA primers at the replication forks gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01920 AFK63_RS01925 AFK63_01930 rpsU rpsU 388011 388226 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01925 AFK63_RS01930 AFK63_01935 AFK63_RS01930 388474 389487 + UGMP family protein universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01930 AFK63_RS01935 AFK63_01940 AFK63_RS01935 389528 390145 - glycerol-3-phosphate acyltransferase involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01935 AFK63_RS01940 AFK63_01945 folB folB 390253 390612 + dihydroneopterin aldolase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01940 AFK63_RS01945 AFK63_01950 AFK63_RS01945 390737 391555 + UDP pyrophosphate phosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01945 AFK63_RS01950 AFK63_01955 AFK63_RS01950 391561 392808 - tRNA nucleotidyl transferase gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01950 AFK63_RS01955 AFK63_01960 AFK63_RS01955 392904 393518 - hypothetical protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01955 AFK63_RS01960 AFK63_01965 AFK63_RS01960 393768 395069 + adenylate cyclase gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01960 AFK63_RS01965 AFK63_01970 AFK63_RS01965 395090 397927 + bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase%3B also catalyzes the reverse reaction - deadenylation%3B adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01965 AFK63_RS01970 AFK63_01975 AFK63_RS01970 397995 399422 + heptose 1-phosphate adenyltransferase catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01970 AFK63_RS01975 AFK63_01980 AFK63_RS01975 399476 399841 - hypothetical protein gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01975 AFK63_RS01980 AFK63_01985 ribB ribB 400256 400909 + 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01980 AFK63_RS01985 AFK63_01990 AFK63_RS01985 400977 401759 - zinc transporter ZupT gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01985 AFK63_RS01990 AFK63_01995 AFK63_RS01990 401955 402743 + dioxygenase seems to be involved in biofilm formation%3B in asymptomatic bacteriuria E. coli strains 83972 and VR50%2C the ygiD gene is upregulated during biofilm formation in urine gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01990 AFK63_RS01995 AFK63_02000 AFK63_RS01995 402771 403931 - hypothetical protein gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS01995 AFK63_RS02000 AFK63_02005 AFK63_RS02000 403935 404588 - hypothetical protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02000 AFK63_RS02005 AFK63_02010 AFK63_RS02005 404741 406231 - membrane protein gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02005 AFK63_RS02010 AFK63_02015 nudF nudF 406445 407077 + ADP-ribose pyrophosphatase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02010 AFK63_RS02015 AFK63_02020 AFK63_RS02015 407080 407502 + dehydrogenase gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02015 AFK63_RS02020 AFK63_02025 AFK63_RS02020 407527 408354 + diguanylate phosphodiesterase gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02020 AFK63_RS02025 AFK63_02030 AFK63_RS02025 408354 408929 + esterase Displays esterase activity toward palmitoyl-CoA and pNP-butyrate gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02025 AFK63_RS02030 AFK63_02035 AFK63_RS02030 408972 410864 + DNA topoisomerase IV subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02030 AFK63_RS02035 AFK63_02040 AFK63_RS02035 411123 412778 + malonate decarboxylase subunit alpha gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02035 AFK63_RS02040 AFK63_02045 AFK63_RS02040 412778 413638 + triphosphoribosyl-dephospho-CoA synthase catalyzes the reversible formation of 2'-(5''-triphosphoribosyl)-3'dephospho-CoA from 3-dephospho-CoA gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02040 AFK63_RS02045 AFK63_02050 AFK63_RS02045 413648 413947 + malonate decarboxylase ACP gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02045 AFK63_RS02050 AFK63_02055 AFK63_RS02050 413940 414773 + malonate decarboxylase subunit beta The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02050 AFK63_RS02055 AFK63_02060 AFK63_RS02055 414773 415573 + malonate decarboxylase subunit gamma gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02055 AFK63_RS02060 AFK63_02065 AFK63_RS02060 415749 416708 + transporter gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02060 AFK63_RS02065 AFK63_02070 AFK63_RS02065 416712 417329 + phosphoribosyl-dephospho-CoA transferase Catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02065 AFK63_RS02070 AFK63_02075 AFK63_RS02070 417326 418228 + malonate decarboxylase subunit epsilon gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02070 AFK63_RS02075 AFK63_02080 AFK63_RS02075 418225 419154 - LysR family transcriptional regulator gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02075 AFK63_RS02080 AFK63_02085 AFK63_RS02080 419337 421517 + peroxidase gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02080 AFK63_RS02085 AFK63_02090 AFK63_RS02085 421616 421930 - quinol monooxygenase catalyzes the oxidation of menadiol to menadione gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02085 AFK63_RS02090 AFK63_02095 AFK63_RS02090 421962 422543 - NADPH quinone reductase MdaB involved in drug resistance gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02090 AFK63_RS02095 AFK63_02100 AFK63_RS02095 422926 425196 + DNA topoisomerase IV subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02095 AFK63_RS02100 AFK63_02105 AFK63_RS02100 425445 426182 + acyl-phosphate glycerol 3-phosphate acyltransferase catalyzes the formation of 1%2C2-diacyl-sn-glycerol 3-phosphate from 1-acyl-sn-glycerol 3-phosphate using either acyl-CoA or acyl-ACP gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02100 AFK63_RS02105 AFK63_02110 AFK63_RS02105 426232 427644 + cell division protein FtsI septal ring component that protects the divisome from stress gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02105 AFK63_RS02110 AFK63_02115 AFK63_RS02110 427817 428953 - coproporphyrinogen III oxidase gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02110 AFK63_RS02115 AFK63_02120 AFK63_RS02115 428946 429539 - nucleoside-triphosphate diphosphatase HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02115 AFK63_RS02120 AFK63_02125 AFK63_RS02120 429543 429845 - hypothetical protein gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02120 AFK63_RS02125 AFK63_02130 AFK63_RS02125 429842 430396 - membrane protein gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02125 AFK63_RS02130 AFK63_02135 AFK63_RS02130 430412 431125 - YggS family pyridoxal phosphate enzyme gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02130 AFK63_RS02135 AFK63_02140 AFK63_RS02135 431141 432157 + Twitching motility protein PilT gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02135 AFK63_RS02140 AFK63_02145 AFK63_RS02140 432154 434412 - fumarate reductase gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02140 AFK63_RS02145 AFK63_02150 AFK63_RS02145 434475 435167 + IclR family transcriptional regulator gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02145 AFK63_RS02150 AFK63_02155 AFK63_RS02150 435322 435738 - Holliday junction DNA helicase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02150 AFK63_RS02155 AFK63_02160 AFK63_RS02155 435738 436301 - hypothetical protein gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02155 AFK63_RS02160 AFK63_02165 AFK63_RS02160 436413 437360 - glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02160 AFK63_RS02165 AFK63_02170 AFK63_RS02165 437373 438104 - 16S rRNA methyltransferase in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02165 AFK63_RS02170 AFK63_02175 AFK63_RS02170 438178 438885 - DNA-specific endonuclease I gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02170 AFK63_RS02175 AFK63_02180 AFK63_RS02175 438974 439474 - hypothetical protein gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02175 AFK63_RS02180 AFK63_02185 AFK63_RS02180 439814 440662 + nucleoside-specific channel-forming protein Tsx receptor of phage T6 and colicin K%3B involved in the transfer of deoxyribo- and ribo-nucleotides across the outer membrane gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02180 AFK63_RS02185 AFK63_02190 AFK63_RS02185 440723 442117 - D-galactose transporter GalP gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02185 AFK63_RS02190 AFK63_02195 AFK63_RS02190 442533 443687 - S-adenosylmethionine synthetase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02190 AFK63_RS02195 AFK63_02200 AFK63_RS02195 444483 446459 + arginine decarboxylase catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02195 AFK63_RS02200 AFK63_02205 AFK63_RS02200 446685 447605 + agmatinase catalyzes the formation of putrescine from agmatine gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02200 AFK63_RS02205 AFK63_02210 AFK63_RS02205 447715 448473 - metalloprotease gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02205 AFK63_RS02210 AFK63_02215 AFK63_RS02210 448751 450742 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02210 AFK63_RS02215 AFK63_02220 AFK63_RS02215 450799 451935 - ADP-ribosylglycohydrolase gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02215 AFK63_RS02220 AFK63_02225 gapA gapA 452291 453310 + glyceraldehyde-3-phosphate dehydrogenase required for glycolysis%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02220 AFK63_RS02225 AFK63_02230 AFK63_RS02225 453386 454549 + phosphoglycerate kinase gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02225 AFK63_RS02230 AFK63_02235 AFK63_RS02230 454646 455725 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02230 AFK63_RS02235 AFK63_02240 AFK63_RS02235 455915 456853 + mechanosensitive ion channel protein MscS participates in the regulation of osmotic pressure changes within the cel gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02235 AFK63_RS02240 AFK63_02245 AFK63_RS02240 457000 457635 + arginine exporter protein Involved in the export of arginine gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02240 AFK63_RS02245 AFK63_02250 AFK63_RS02245 457739 458524 + hypothetical protein gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02245 AFK63_RS02250 AFK63_02255 AFK63_RS02250 458553 459446 - chromosome replication initiation inhibitor protein specific inhibitor of chromosomal initiation of replication in vitro%3B binds the three 13-mers in the origin (oriC) to block initiation of replication%3B also controls genes involved in arginine transport gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02250 AFK63_RS02255 AFK63_02260 AFK63_RS02255 459614 460273 + ribose 5-phosphate isomerase catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02255 AFK63_RS02260 AFK63_02265 AFK63_RS02260 460542 461780 + D-3-phosphoglycerate dehydrogenase catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis%3B can also reduce alpha ketoglutarate to form 2-hydroxyglutarate gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02260 AFK63_RS02265 AFK63_02270 AFK63_RS02265 461883 462479 - 5-formyltetrahydrofolate cyclo-ligase ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms%3B unknown function gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02265 AFK63_RS02270 AFK63_02275 AFK63_RS02270 462720 463049 - cell division protein ZapA gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02270 AFK63_RS02275 AFK63_02280 AFK63_RS02275 463205 463789 + hypothetical protein the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers%3B function unknown gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02275 AFK63_RS02280 AFK63_02285 AFK63_RS02280 463813 465129 + proline aminopeptidase P II exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue%3B substrate can be as short as a dipeptide gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02280 AFK63_RS02285 AFK63_02290 AFK63_RS02285 465126 466304 + 2-octaprenyl-6-methoxyphenyl hydroxylase Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1%2C4-benzoquinone gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02285 AFK63_RS02290 AFK63_02295 AFK63_RS02290 466315 467517 + oxidoreductase gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02290 AFK63_RS02295 AFK63_02300 gcvT gcvT 467940 469037 + glycine cleavage system protein T catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate%2C causing the release of ammonia and the generation of reduced GcvH protein gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02295 AFK63_RS02300 AFK63_02305 AFK63_RS02300 469061 469450 + glycine cleavage system protein H part of multienzyme complex composed of H%2C L%2C P%2C and T proteins which catalyzes oxidation of glycine to yield carbon dioxide%2C ammonia%2C 5%2C10-CH2-H4folate and a reduced pyridine nucleotide%3B protein H is involved in transfer of methylamine group from the P to T protein%3B covalently bound to a lipoyl cofactor gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02300 AFK63_RS02305 AFK63_02310 AFK63_RS02305 469584 472457 + glycine dehydrogenase acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02305 AFK63_RS02310 AFK63_02315 AFK63_RS02310 472658 473401 + hypothetical protein gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02310 AFK63_RS02315 AFK63_02320 AFK63_RS02315 473575 475008 - 6-phospho-beta-glucosidase gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02315 AFK63_RS02320 AFK63_02325 AFK63_RS02320 475160 475888 - transcriptional regulator gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02320 AFK63_RS02325 AFK63_02330 AFK63_RS02325 476067 476381 + valyl-tRNA synthetase gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02325 AFK63_RS02330 AFK63_02335 AFK63_RS02330 476546 477199 + hemolysin gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02330 AFK63_RS02335 AFK63_02340 ygfZ ygfZ 477330 478319 - global regulator physiological role is not clear%3B not essential for growth but mutants grow poorly%3B mutations suppress hda null mutations%3B may be involved in regulation of ATP-DnaA levels%3B may also be involved in regulation of tRNA modifications%3B can bind folic acid and tetrahydrofolate%3B forms a three domain ring-like structure with a central channel%3B structurally similar to DMGO protein from A. globiformis%3B shows sequence similarity to yeast CAF17 transcriptional regulato%3B Hda supressor gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02335 AFK63_RS02340 AFK63_02345 AFK63_RS02340 478596 478862 + hypothetical protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02340 AFK63_RS02345 AFK63_02350 AFK63_RS02345 478843 479259 + membrane protein gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02345 AFK63_RS02350 AFK63_02355 AFK63_RS02350 479291 479812 - flavodoxin FldB An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02350 AFK63_RS02355 AFK63_02360 xerD xerD 479914 480810 + site-specific tyrosine recombinase XerD site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B XerD specifically exchanges the bottom strands%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02355 AFK63_RS02360 AFK63_02365 AFK63_RS02360 480833 481552 + protein-disulfide isomerase DsbC%3B periplasmic protein with protein disulfide isomerase activity%3B this protein also shows disulfide oxidoreductase activity gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02360 AFK63_RS02365 AFK63_02370 AFK63_RS02365 481556 483289 + ssDNA exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02365 AFK63_RS02370 AFK63_02375 AFK63_RS02370 483603 484484 + peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02370 AFK63_RS02375 AFK63_02380 lysS lysS 484494 486011 + lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02375 AFK63_RS02380 AFK63_02385 AFK63_RS02380 486156 486905 + lipoprotein gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02380 AFK63_RS02385 AFK63_02390 AFK63_RS02385 487015 487088 + tRNA-Gly tRNA gene476 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02385 AFK63_RS02390 AFK63_02395 AFK63_RS02390 487297 487524 + hypothetical protein gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02390 AFK63_RS02395 AFK63_02400 AFK63_RS02395 488055 488675 + lysine transporter LysE gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02395 AFK63_RS02400 AFK63_02405 AFK63_RS02400 488837 489457 + hypothetical protein gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02400 AFK63_RS02405 AFK63_02410 AFK63_RS02405 489609 490790 + acetyl-CoA acetyltransferase gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02405 AFK63_RS02410 AFK63_02415 AFK63_RS02410 491178 491858 + porin gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02410 AFK63_RS02415 AFK63_02420 AFK63_RS02415 492120 493298 - oligogalacturonate lyase gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02415 AFK63_RS02420 AFK63_02425 AFK63_RS02420 493539 493787 + hypothetical protein gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02420 AFK63_RS02425 AFK63_02430 AFK63_RS02425 493923 494684 + 2-deoxy-D-gluconate 3-dehydrogenase catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02425 AFK63_RS02430 AFK63_02435 AFK63_RS02430 495143 496273 - oligogalacturonate lyase gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02430 AFK63_RS02435 AFK63_02440 AFK63_RS02435 496344 497633 - sugar ABC transporter substrate-binding protein gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02435 AFK63_RS02440 AFK63_02445 AFK63_RS02440 497647 498774 - sugar ABC transporter ATP-binding protein gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02440 AFK63_RS02445 AFK63_02450 AFK63_RS02445 498787 499701 - sugar ABC transporter permease gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02445 AFK63_RS02450 AFK63_02455 AFK63_RS02450 499694 500584 - sugar ABC transporter gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02450 AFK63_RS02455 AFK63_02460 AFK63_RS02455 501184 502326 + O-antigen length regulator in Salmonella is responsible for long O-antigen polymerization%3B may be part of the ferric enterobactin transport system%3B necessary for enetrobactin uptake gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02455 AFK63_RS02460 AFK63_02465 AFK63_RS02460 502382 502705 - cupin gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02460 AFK63_RS02465 AFK63_02470 AFK63_RS02465 502857 503585 + racemase gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02465 AFK63_RS02470 AFK63_02475 AFK63_RS02470 503536 504474 - transcriptional regulator gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02470 AFK63_RS02475 AFK63_02480 AFK63_RS02475 504752 506014 + diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02475 AFK63_RS02480 AFK63_02485 AFK63_RS02480 505991 507028 - LacI family transcriptional regulator gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02480 AFK63_RS02485 AFK63_02490 AFK63_RS02485 507314 508651 + PTS lactose transporter subunit IIC gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02485 AFK63_RS02490 AFK63_02495 AFK63_RS02490 508659 510086 + 6-phospho-beta-glucosidase gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02490 AFK63_RS02495 AFK63_02500 AFK63_RS02495 510097 510414 + PTS cellobiose transporter subunit IIB gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02495 AFK63_RS02500 AFK63_02505 AFK63_RS02500 510476 511249 + transcriptional regulator gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02500 AFK63_RS02505 AFK63_02510 AFK63_RS02505 511246 511740 + GNAT family acetyltransferase gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02505 AFK63_RS02510 AFK63_02515 AFK63_RS02510 511701 512717 - transcriptional regulator controls transcription of galETKM gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02510 AFK63_RS02515 AFK63_02520 AFK63_RS02515 513213 515372 + acyl-ACP synthetase Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02515 AFK63_RS02520 AFK63_02525 AFK63_RS02520 515365 516558 + lysophospholipid transporter LplT gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02520 AFK63_RS02525 AFK63_02530 tas tas 516606 517646 - aldo/keto reductase complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain%3B member of the aldo/keto reductase 2 family%3B crystal structure of purified Escherichia coli protein shows bound NADPH gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02525 AFK63_RS02530 AFK63_02535 AFK63_RS02530 517783 518001 - hypothetical protein gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02530 AFK63_RS02535 AFK63_02540 AFK63_RS02535 518130 518843 - membrane protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02535 AFK63_RS02540 AFK63_02545 AFK63_RS02540 518921 519607 - DNA mismatch repair protein MutH%3B Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02540 AFK63_RS02545 AFK63_02550 AFK63_RS02545 520291 520824 + RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02545 AFK63_RS02550 AFK63_02555 AFK63_RS02550 520837 523083 + phosphoenolpyruvate-protein phosphotransferase member of a second PTS chain involved in nitrogen metabolism%3B PtsP phosphorylates NPr gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02550 AFK63_RS02555 AFK63_02560 AFK63_RS02555 523245 524120 + prolipoprotein diacylglyceryl transferase gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02555 AFK63_RS02560 AFK63_02565 AFK63_RS02560 524127 524921 + thymidylate synthase gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02560 AFK63_RS02565 AFK63_02570 AFK63_RS02565 525101 525574 + hypothetical protein gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02565 AFK63_RS02570 AFK63_02575 AFK63_RS02570 525565 526128 + hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02570 AFK63_RS02575 AFK63_02580 AFK63_RS02575 526531 526860 + hypothetical protein gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02575 AFK63_RS02580 AFK63_02585 recC recC 526876 530250 + exonuclease V subunit gamma catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02580 AFK63_RS02585 AFK63_02590 AFK63_RS02585 530352 533240 + protease degrades small peptides gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02585 AFK63_RS02590 AFK63_02595 recB recB 533237 536779 + exonuclease V subunit beta helicase/nuclease%3B with RecCD catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02590 AFK63_RS02595 AFK63_02600 recD recD 536776 538608 + exonuclease V subunit alpha helicase/nuclease%3B with RecBC catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02595 AFK63_RS02600 AFK63_02605 AFK63_RS02600 538646 539977 - N-acetylglutamate synthase catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02600 AFK63_RS02605 AFK63_02610 amiC amiC 540204 541457 + N-acetylmuramoyl-L-alanine amidase hydrolyzes the bond between N-acetylmuramic acid and amino acid residues in peptidoglycan gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02605 AFK63_RS02610 AFK63_02615 AFK63_RS02610 541549 541625 - tRNA-Met tRNA gene521 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02610 AFK63_RS02615 AFK63_02620 AFK63_RS02615 541667 541743 - tRNA-Met tRNA gene522 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02615 AFK63_RS02620 AFK63_02625 mltA mltA 541947 543044 + murein transglycosylase membrane-bound%2C lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02620 AFK63_RS02625 AFK63_02630 AFK63_RS02625 543154 543963 + sulfur acceptor protein CsdL accepts sulfur from CsdA gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02625 AFK63_RS02630 AFK63_02635 AFK63_RS02630 543964 544407 - Fe-S metabolism protein SufE gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02630 AFK63_RS02635 AFK63_02640 AFK63_RS02635 544408 545610 - cysteine sulfinate desulfinase gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02635 AFK63_RS02640 AFK63_02645 AFK63_RS02640 545803 546030 + hypothetical protein gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02640 AFK63_RS02645 AFK63_02650 AFK63_RS02645 546371 547288 + glycine cleavage system transcriptional activator GcvA Glycine cleavage system transcriptional activator%3B activates the gcvTHP operon in the presence of glycine and represses the operon in its absence gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02645 AFK63_RS02650 AFK63_02655 AFK63_RS02650 547334 547729 + hypothetical protein gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02650 AFK63_RS02655 AFK63_02660 AFK63_RS02655 547722 548822 + 23S rRNA methyltransferase gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02655 AFK63_RS02660 AFK63_02665 AFK63_RS02660 548897 549652 - flap endonuclease-like protein similar to flap endonuclease%3B FEN family%3B protein from E. coli does not have exonuclease activity gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02660 AFK63_RS02665 AFK63_02670 AFK63_RS02665 549783 551150 - serine dehydratase catalyzes the formation of pyruvate from serine gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02665 AFK63_RS02670 AFK63_02675 AFK63_RS02670 551217 552503 - serine/threonine protein kinase gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02670 AFK63_RS02675 AFK63_02680 AFK63_RS02675 552956 554320 - LOG family protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02675 AFK63_RS02680 AFK63_02685 queF queF 554438 555283 - 7-cyano-7-deazaguanine reductase catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02680 AFK63_RS02685 AFK63_02690 AFK63_RS02685 555353 555898 + secretion protein gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02685 AFK63_RS02690 AFK63_02695 AFK63_RS02690 556538 556867 + hypothetical protein gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02690 AFK63_RS02695 AFK63_02700 AFK63_RS02695 556864 557661 + tRNA pseudouridine synthase C catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02695 AFK63_RS02700 AFK63_02705 AFK63_RS02700 557665 558114 + flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02700 AFK63_RS02705 AFK63_02710 AFK63_RS02705 558158 560917 - two-component system sensor histidine kinase/response regulator part of the two-component regulatory system with UvrY%3B involved in the regulation of carbon metabolism via the csrA/csrB regulatory system gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02705 AFK63_RS02710 AFK63_02715 rumA rumA 560975 562273 + 23S rRNA methyltransferase in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA%3B binds an iron-sulfur cluster [4Fe-4S] gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02710 AFK63_RS02715 AFK63_02720 relA relA 562326 564560 + (p)ppGpp synthetase (p)ppGpp synthetase%3B catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02715 AFK63_RS02720 AFK63_02725 mazG mazG 564670 565461 + nucleoside triphosphate hydrolase functions in degradation of stringent response intracellular messenger ppGpp%3B in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF%3B activity of MazG is inhibited by MazEF in vitro%3B ppGpp inhibits mazEF expression%3B MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation%3B MazG also interacts with the GTPase protein Era gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02720 AFK63_RS02725 AFK63_02730 pyrG pyrG 565687 567324 + CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02725 AFK63_RS02730 AFK63_02735 eno eno 567410 568708 + enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02730 AFK63_RS02735 AFK63_02740 AFK63_RS02735 568826 569653 - RpiR family transcriptional regulator gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02735 AFK63_RS02740 AFK63_02745 AFK63_RS02740 569823 571376 + PTS glucose transporter subunit IIB gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02740 AFK63_RS02745 AFK63_02750 AFK63_RS02745 571385 572074 + N-acetylmannosamine-6-phosphate 2-epimerase gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02745 AFK63_RS02750 AFK63_02755 AFK63_RS02750 572060 573019 - hypothetical protein gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02750 AFK63_RS02755 AFK63_02760 AFK63_RS02755 573216 573887 + 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02755 AFK63_RS02760 AFK63_02765 AFK63_RS02760 573965 574327 - 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02760 AFK63_RS02765 AFK63_02770 cysJ cysJ 574632 576434 + sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02765 AFK63_RS02770 AFK63_02775 AFK63_RS02770 576434 578146 + sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02770 AFK63_RS02775 AFK63_02780 AFK63_RS02775 578308 579042 + phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02775 AFK63_RS02780 AFK63_02785 AFK63_RS02780 579070 580059 - alkaline phosphatase catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02780 AFK63_RS02785 AFK63_02790 AFK63_RS02785 580304 581719 + sirohydrochlorin ferrochelatase gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02785 AFK63_RS02790 AFK63_02795 AFK63_RS02790 581729 582637 + sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02790 AFK63_RS02795 AFK63_02800 cysN cysN 582647 584074 + sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02795 AFK63_RS02800 AFK63_02805 AFK63_RS02800 584074 584679 + adenylylsulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02800 AFK63_RS02805 AFK63_02810 AFK63_RS02805 584729 585052 + hypothetical protein gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02805 AFK63_RS02810 AFK63_02815 ftsB ftsB 585215 585526 + hypothetical protein forms a complex with FtsL and FtsQ%3B colocalizes to the septal region of the dividing cell%3B membrane protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02810 AFK63_RS02815 AFK63_02820 AFK63_RS02815 585546 586256 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02815 AFK63_RS02820 AFK63_02825 ispF ispF 586256 586735 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02820 AFK63_RS02825 AFK63_02830 truD truD 586732 587781 + tRNA pseudouridine synthase D catalyzes the modification of U13 in tRNA(Glu) gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02825 AFK63_RS02830 AFK63_02835 surE surE 588249 589010 + stationary phase survival protein SurE broad specificity 5'(3')-nucleotidase and polyphosphatase gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02830 AFK63_RS02835 AFK63_02840 pcm pcm 589004 589630 + protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02835 AFK63_RS02840 AFK63_02845 nlpD nlpD 589758 590897 + lipoprotein NlpD outer membrane lipoprotein involved in stationary-phase cell survival%3B similar to LppB virulence determinant from Haemophilus somnus gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02840 AFK63_RS02845 AFK63_02850 AFK63_RS02845 590957 591949 + RNA polymerase sigma factor RpoS sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor controls a regulon of genes required for protection against external stresses gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02845 AFK63_RS02850 AFK63_02855 AFK63_RS02850 592010 592384 - hypothetical protein gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02850 AFK63_RS02855 AFK63_02860 AFK63_RS02855 592384 593763 - DSBA oxidoreductase gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02855 AFK63_RS02860 AFK63_02865 AFK63_RS02860 593872 594768 + LysR family transcriptional regulator gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02860 AFK63_RS02865 AFK63_02870 AFK63_RS02865 594771 595181 - transcriptional regulator gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02865 AFK63_RS02870 AFK63_02875 AFK63_RS02870 595371 595970 + phenolic acid decarboxylase subunit B gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02870 AFK63_RS02875 AFK63_02880 AFK63_RS02875 595960 597390 + phenolic acid decarboxylase gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02875 AFK63_RS02880 AFK63_02885 AFK63_RS02880 597400 597636 + 4-hydroxybenzoate decarboxylase gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02880 AFK63_RS02885 AFK63_02890 AFK63_RS02885 597757 600318 - DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02885 AFK63_RS02890 AFK63_02895 AFK63_RS02890 600815 601216 + hypothetical protein gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02890 AFK63_RS02895 AFK63_02900 AFK63_RS02895 601203 601568 + hypothetical protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02895 AFK63_RS02900 AFK63_02905 AFK63_RS02900 601672 602376 - GNAT family acetyltransferase gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02900 AFK63_RS02905 AFK63_02910 AFK63_RS02905 602584 604251 + chemotaxis protein serine sensor receptor gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02905 AFK63_RS02910 AFK63_02915 AFK63_RS02910 604319 604531 - hypothetical protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02910 AFK63_RS02915 AFK63_02920 AFK63_RS02915 604705 605472 + ABC transporter substrate-binding protein gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02915 AFK63_RS02920 AFK63_02925 AFK63_RS02920 605542 606306 + amino acid ABC transporter permease gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02920 AFK63_RS02925 AFK63_02930 AFK63_RS02925 606293 607015 + amino acid ABC transporter ATPase gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02925 AFK63_RS02930 AFK63_02935 AFK63_RS02930 607131 608213 + murein hydrolase effector LrgB membrane-bound lytic murein transglycosylase B%3B catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02930 AFK63_RS02935 AFK63_02940 AFK63_RS02935 608354 608851 + hypothetical protein gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02935 AFK63_RS02940 AFK63_02945 recA recA 608940 610004 + recombinase RecA catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02940 AFK63_RS02945 AFK63_02950 recX recX 610062 610559 + recombination regulator RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02945 AFK63_RS02950 AFK63_02955 AFK63_RS02950 610695 613322 + alanyl-tRNA synthetase gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02950 AFK63_RS02955 AFK63_02960 AFK63_RS02955 613567 613752 + pleiotropic regulatory protein for carbon source metabolism affects carbohydrate metabolism%3B has regulatory role in many processes gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02955 AFK63_RS02960 AFK63_02965 AFK63_RS02960 614071 614163 + tRNA-Ser tRNA gene591 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02960 AFK63_RS02965 AFK63_02970 AFK63_RS02965 614168 614244 + tRNA-Arg tRNA gene592 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02965 AFK63_RS02970 AFK63_02975 AFK63_RS02970 614308 614384 + tRNA-Arg tRNA gene593 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02970 AFK63_RS02975 AFK63_02980 AFK63_RS02975 614580 614656 + tRNA-Arg tRNA gene594 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02975 AFK63_RS02980 AFK63_02985 AFK63_RS02980 614851 614927 + tRNA-Arg tRNA gene595 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02980 AFK63_RS02985 AFK63_02990 AFK63_RS02985 615234 615800 + 6-phosphogluconate phosphatase YqaB%3B catalyzes the dephosphorylation of fructose 1-phosphate%2C 6-phosphogluconate and p-nitrophenyl phosphate (pNPP)%3B presents beta-phosphoglucomutase activity at a lower extent gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02985 AFK63_RS02990 AFK63_02995 AFK63_RS02990 615797 616225 + hypothetical protein gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02990 AFK63_RS02995 AFK63_03000 AFK63_RS02995 616318 617874 + glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS02995 AFK63_RS03000 AFK63_03005 AFK63_RS03000 618028 618543 + S-ribosylhomocysteinase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03000 AFK63_RS03005 AFK63_03010 AFK63_RS03005 618970 621510 + diguanylate cyclase gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03005 AFK63_RS03010 AFK63_03015 emrB emrB 621569 623110 - multidrug resistance protein B multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03010 AFK63_RS03015 AFK63_03020 AFK63_RS03015 623125 624300 - multidrug transporter with ErmA and TolC forms a multidrug efflux system gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03015 AFK63_RS03020 AFK63_03025 AFK63_RS03020 624437 624967 - transcriptional regulator DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux%3B negative regulator of the multidrug operon emrAB gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03020 AFK63_RS03025 AFK63_03030 AFK63_RS03025 625516 626700 - transporter gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03025 AFK63_RS03030 AFK63_03035 proX proX 626942 627937 - glycine/betaine ABC transporter substrate-binding protein with ProVW%2C part of the high-affinity transport system for the osmoprotectant glycine betaine gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03030 AFK63_RS03035 AFK63_03040 AFK63_RS03035 627991 629061 - glycine/betaine ABC transporter permease with ProVX is involved in the high-affinity uptake of glycine betaine gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03035 AFK63_RS03040 AFK63_03045 AFK63_RS03040 629054 630256 - glycine/betaine ABC transporter ATP-binding protein with ProWX is involved in the high-affinity uptake of glycine betaine gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03040 AFK63_RS03045 AFK63_03050 AFK63_RS03045 630611 631573 - ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03045 AFK63_RS03050 AFK63_03055 AFK63_RS03050 631583 633733 - hypothetical protein gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03050 AFK63_RS03055 AFK63_03060 nrdI nrdI 633715 634116 - ribonucleotide reductase stimulatory protein in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03055 AFK63_RS03060 AFK63_03065 AFK63_RS03060 634113 634358 - glutaredoxin gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03060 AFK63_RS03065 AFK63_03070 AFK63_RS03065 634638 634964 - hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03065 AFK63_RS03070 AFK63_03075 AFK63_RS03070 635125 635469 + hypothetical protein gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03070 AFK63_RS03075 AFK63_03080 AFK63_RS03075 635481 635936 - alanine transporter gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03075 AFK63_RS03080 AFK63_03085 AFK63_RS03080 636219 636422 + hypothetical protein gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03080 AFK63_RS03085 AFK63_03090 AFK63_RS03085 636479 636856 - hypothetical protein gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03085 AFK63_RS03090 AFK63_03095 AFK63_RS03090 636904 637083 - hypothetical protein gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03090 AFK63_RS03095 AFK63_03100 AFK63_RS03095 637804 639681 + chemoreceptor gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03095 AFK63_RS03100 AFK63_03105 AFK63_RS03100 639857 640231 + hypothetical protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03100 AFK63_RS03105 AFK63_03110 AFK63_RS03105 640412 640813 - hypothetical protein gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03105 AFK63_RS03110 AFK63_03115 AFK63_RS03110 642071 654259 + hypothetical protein gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03110 AFK63_RS03115 AFK63_03120 AFK63_RS03115 654347 655696 + type I secretion system outer membrane protein gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03115 AFK63_RS03120 AFK63_03125 AFK63_RS03120 655720 657855 + ATP-binding protein gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03120 AFK63_RS03125 AFK63_03130 AFK63_RS03125 657865 659034 + secretion protein HlyD gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03125 AFK63_RS03130 AFK63_03135 smpB smpB 659267 659749 - SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03130 AFK63_RS03135 AFK63_03140 AFK63_RS03135 659898 660335 + hypothetical protein gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03135 AFK63_RS03140 AFK63_03145 AFK63_RS03140 660325 660615 + hypothetical protein gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03140 AFK63_RS03145 AFK63_03150 AFK63_RS03145 660733 661080 - membrane biogenesis protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03145 AFK63_RS03150 AFK63_03155 AFK63_RS03150 661299 662960 - DNA repair protein RecN gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03150 AFK63_RS03155 AFK63_03160 ppnK ppnK 663047 663925 - inorganic polyphosphate kinase catalyzes the phosphorylation of NAD to NADP gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03155 AFK63_RS03160 AFK63_03165 AFK63_RS03160 664048 664641 + co-chaperone GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03160 AFK63_RS03165 AFK63_03170 AFK63_RS03165 664701 665990 - hypothetical protein gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03165 AFK63_RS03170 AFK63_03175 AFK63_RS03170 666018 666809 - membrane protein gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03170 AFK63_RS03175 AFK63_03180 AFK63_RS03175 666972 668333 + signal recognition particle protein gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03175 AFK63_RS03180 AFK63_03185 AFK63_RS03180 668592 668840 + 30S ribosomal protein S16 gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03180 AFK63_RS03185 AFK63_03190 rimM rimM 668859 669407 + 16S rRNA-processing protein RimM Essential for efficient processing of 16S rRNA gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03185 AFK63_RS03190 AFK63_03195 trmD trmD 669438 670211 + tRNA (guanine(37)-N(1))-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03190 AFK63_RS03195 AFK63_03200 AFK63_RS03195 670257 670604 + 50S ribosomal protein L19 gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03195 AFK63_RS03200 AFK63_03205 AFK63_RS03200 670770 671207 + hypothetical protein gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03200 AFK63_RS03205 AFK63_03210 AFK63_RS03205 671262 672629 + membrane protein gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03205 AFK63_RS03210 AFK63_03215 AFK63_RS03210 672828 673898 + phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03210 AFK63_RS03215 AFK63_03220 tyrA tyrA 673909 675030 + chorismate mutase catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03215 AFK63_RS03220 AFK63_03225 AFK63_RS03220 675106 675975 + gluconolactonase gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03220 AFK63_RS03225 AFK63_03230 pheA pheA 676008 677168 - chorismate mutase catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03225 AFK63_RS03230 AFK63_03235 AFK63_RS03230 677420 677761 - translation inhibitor protein RaiA associated with 30S ribosomal subunit%3B interferes with translation elongation gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03230 AFK63_RS03235 AFK63_03240 AFK63_RS03235 678114 679325 + hypothetical protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03235 AFK63_RS03240 AFK63_03245 AFK63_RS03240 679379 680116 - membrane biogenesis protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03240 AFK63_RS03245 AFK63_03250 rluD rluD 680246 681226 + 23S rRNA pseudouridylate synthase responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03245 AFK63_RS03250 AFK63_03255 AFK63_RS03250 681223 681951 + hypothetical protein gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03250 AFK63_RS03255 AFK63_03260 AFK63_RS03255 682081 684654 + protein disaggregation chaperone gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03255 AFK63_RS03260 AFK63_03265 AFK63_RS03260 685089 686644 + 16S ribosomal RNA rRNA gene651 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03260 AFK63_RS03265 AFK63_03270 AFK63_RS03265 686714 686789 + tRNA-Glu tRNA gene652 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03265 AFK63_RS03270 AFK63_03275 AFK63_RS03270 686983 689912 + 23S ribosomal RNA rRNA gene653 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03270 AFK63_RS03275 AFK63_03280 AFK63_RS03275 689989 690104 + 5S ribosomal RNA rRNA gene654 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03275 AFK63_RS03280 AFK63_03285 AFK63_RS03280 691107 692903 - thiamine pyrophosphate-binding protein gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03280 AFK63_RS03285 AFK63_03290 AFK63_RS03285 693059 693514 + hypothetical protein gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03285 AFK63_RS03290 AFK63_03295 AFK63_RS03290 693638 694939 + alpha-ketoglutarate transporter gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03290 AFK63_RS03295 AFK63_03300 AFK63_RS03295 694936 695259 - lipoprotein required for high salt suppression of motility gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03295 AFK63_RS03300 AFK63_03305 pssA pssA 695313 696668 - phosphatidylserine synthase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03300 AFK63_RS03305 AFK63_03310 AFK63_RS03305 696781 699441 - protein acetyltransferase catalyzes the acetylation of lysine gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03305 AFK63_RS03310 AFK63_03315 AFK63_RS03310 699475 700176 - DTW domain-containing protein YfiP gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03310 AFK63_RS03315 AFK63_03320 AFK63_RS03315 700242 700673 - thioredoxin gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03315 AFK63_RS03320 AFK63_03325 AFK63_RS03320 700883 701947 + methyltransferase gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03320 AFK63_RS03325 AFK63_03330 AFK63_RS03325 702004 702693 - uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03325 AFK63_RS03330 AFK63_03335 AFK63_RS03330 703000 703383 + autonomous glycyl radical cofactor GrcA stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03330 AFK63_RS03335 AFK63_03340 AFK63_RS03335 703457 704794 - ATP-dependent RNA helicase SrmB facilitates an early step in the assembly of the 50S subunit of the ribosome gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03335 AFK63_RS03340 AFK63_03345 AFK63_RS03340 704923 705660 + tRNA (adenine-N6)-methyltransferase gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03340 AFK63_RS03345 AFK63_03350 AFK63_RS03345 705645 707264 - L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03345 AFK63_RS03350 AFK63_03355 AFK63_RS03350 707690 708265 + RNA polymerase sigma factor AlgU Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor is involved in heat shock and oxidative stress response gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03350 AFK63_RS03355 AFK63_03360 AFK63_RS03355 708297 708947 + anti-RNA polymerase sigma factor SigE gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03355 AFK63_RS03360 AFK63_03365 rseB rseB 708947 709900 + anti-sigma E factor periplasmic protein%3B interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03360 AFK63_RS03365 AFK63_03370 AFK63_RS03365 709897 710376 + SoxR reducing system protein RseC involved in the reduction of the SoxR iron-sulfur cluster gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03365 AFK63_RS03370 AFK63_03375 AFK63_RS03370 710577 712376 + elongation factor 4 gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03370 AFK63_RS03375 AFK63_03380 AFK63_RS03375 712391 713356 + signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03375 AFK63_RS03380 AFK63_03385 rnc rnc 713528 714208 + ribonuclease III cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03380 AFK63_RS03385 AFK63_03390 AFK63_RS03385 714205 715110 + GTPase Era gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03385 AFK63_RS03390 AFK63_03395 recO recO 715120 715857 + DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03390 AFK63_RS03395 AFK63_03400 AFK63_RS03395 715932 716663 + pyridoxine 5'-phosphate synthase involved in the de novo synthesis of pyridoxine (Vitamin B6) gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03395 AFK63_RS03400 AFK63_03405 acpS acpS 716663 717043 + 4'-phosphopantetheinyl transferase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03400 AFK63_RS03405 AFK63_03410 AFK63_RS03405 717040 717300 - ferredoxin gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03405 AFK63_RS03410 AFK63_03415 AFK63_RS03410 717357 718205 - transcriptional regulator gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03410 AFK63_RS03415 AFK63_03420 murQ murQ 718327 719220 + N-acetylmuramic acid 6-phosphate etherase catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate%3B involved in MurNAc dissimilation pathway gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03415 AFK63_RS03420 AFK63_03425 AFK63_RS03420 719234 720601 + PTS sugar transporter subunit IIC gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03420 AFK63_RS03425 AFK63_03430 AFK63_RS03425 720605 721240 + hypothetical protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03425 AFK63_RS03430 AFK63_03435 AFK63_RS03430 721702 723261 - murein transglycosylase gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03430 AFK63_RS03435 AFK63_03440 AFK63_RS03435 723529 727419 + phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03435 AFK63_RS03440 AFK63_03445 AFK63_RS03440 728025 729416 + histidine kinase part of the GlrKR two-component signal transduction system involved in the regulation of glmY gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03440 AFK63_RS03445 AFK63_03450 AFK63_RS03445 729413 730189 + membrane protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03445 AFK63_RS03450 AFK63_03455 AFK63_RS03450 730186 731523 + transcriptional regulator with GlrK is part of a two-component signal transduction system regulating glmY gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03450 AFK63_RS03455 AFK63_03460 AFK63_RS03455 731622 731960 + nitrogen regulatory protein P-II indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03455 AFK63_RS03460 AFK63_03465 AFK63_RS03460 732163 733353 - dihydropteridine reductase flavohemoprotein%3B catalyzes the formation of nitrate from nitric oxide%3B can also catalyze the reduction of dihydropteridine gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03460 AFK63_RS03465 AFK63_03470 AFK63_RS03465 733679 734932 + serine hydroxymethyltransferase gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03465 AFK63_RS03470 AFK63_03475 AFK63_RS03470 735002 735364 + MerR family transcriptional regulator gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03470 AFK63_RS03475 AFK63_03480 AFK63_RS03475 735420 735797 + 4-carboxymuconolactone decarboxylase gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03475 AFK63_RS03480 AFK63_03485 AFK63_RS03480 735923 737062 + 3-phenylpropionic acid transporter transporter of 3-phenylpropionate across the inner membrane%3B member of the major facilitator superfamily of transporters gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03480 AFK63_RS03485 AFK63_03490 AFK63_RS03485 737059 738339 - stationary phase inducible protein CsiE gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03485 AFK63_RS03490 AFK63_03495 AFK63_RS03490 738465 739112 + membrane protein gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03490 AFK63_RS03495 AFK63_03500 AFK63_RS03495 739103 740080 + nickel transporter gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03495 AFK63_RS03500 AFK63_03505 AFK63_RS03500 740281 741084 - inositol-1-monophosphatase gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03500 AFK63_RS03505 AFK63_03510 AFK63_RS03505 741206 741949 + tRNA (cytidine/uridine-2'-O-)-methyltransferase catalyzes the fromation of 2'O-methylated cytidine or 2'O-methylated uridine at position 32 in tRNA gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03505 AFK63_RS03510 AFK63_03515 AFK63_RS03510 742074 742562 + Fe-S cluster assembly transcriptional regulator IscR regulates the expression of the iscRSUA operon gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03510 AFK63_RS03515 AFK63_03520 AFK63_RS03515 742679 743893 + cysteine desulfurase catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03515 AFK63_RS03520 AFK63_03525 AFK63_RS03520 743922 744308 + Fe-S cluster assembly scaffold IscU gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03520 AFK63_RS03525 AFK63_03530 iscA iscA 744333 744656 + iron-binding protein forms iron-sulfur clusters of ferredoxin [2FE-2S]%3B binds iron in the presence of the thioredoxin reductase system%3B forms homodimers and tetramers%3B similar to SufA protein gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03525 AFK63_RS03530 AFK63_03535 hscB hscB 744739 745254 + co-chaperone HscB J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone%3B may function in biogenesis of iron-sulfur proteins gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03530 AFK63_RS03535 AFK63_03540 hscA hscA 745270 747120 + chaperone protein HscA involved in the maturation of iron-sulfur cluster-containing proteins gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03535 AFK63_RS03540 AFK63_03545 AFK63_RS03540 747122 747457 + (2Fe-2S) ferredoxin gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03540 AFK63_RS03545 AFK63_03550 AFK63_RS03545 747459 747659 + hypothetical protein gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03545 AFK63_RS03550 AFK63_03555 AFK63_RS03550 747723 749009 + aminopeptidase B catalyzes the removal of an N-terminal amino acid from a peptide or arylamide gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03550 AFK63_RS03555 AFK63_03560 AFK63_RS03555 749175 749972 + enhanced serine sensitivity protein SseB enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03555 AFK63_RS03560 AFK63_03565 AFK63_RS03560 750182 752290 + hypothetical protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03560 AFK63_RS03565 AFK63_03570 AFK63_RS03565 752403 754526 + hypothetical protein gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03565 AFK63_RS03570 AFK63_03575 AFK63_RS03570 754597 755370 - RpiR family transcriptional regulator gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03570 AFK63_RS03575 AFK63_03580 sseA sseA 755374 756219 - 3-mercaptopyruvate sulfurtransferase catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03575 AFK63_RS03580 AFK63_03585 AFK63_RS03580 756312 757676 - 6-phospho-alpha-glucosidase gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03580 AFK63_RS03585 AFK63_03590 AFK63_RS03585 757689 759233 - PTS glucose transporter subunit IIBC gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03585 AFK63_RS03590 AFK63_03595 AFK63_RS03590 759569 764518 + hypothetical protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03590 AFK63_RS03595 AFK63_03600 AFK63_RS03595 764532 766862 + penicillin-binding protein 1C penicillin-insensitive transglycosylase/transpeptidase gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03595 AFK63_RS03600 AFK63_03605 AFK63_RS03600 767030 767461 + nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03600 AFK63_RS03605 AFK63_03610 AFK63_RS03605 767642 768808 + 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03605 AFK63_RS03610 AFK63_03615 AFK63_RS03610 769229 770236 + cytoskeletal protein RodZ gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03610 AFK63_RS03615 AFK63_03620 AFK63_RS03615 770263 771381 + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03615 AFK63_RS03620 AFK63_03625 hisS hisS 771496 772770 + histidyl-tRNA synthetase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03620 AFK63_RS03625 AFK63_03630 AFK63_RS03625 772806 773426 + membrane protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03625 AFK63_RS03630 AFK63_03635 AFK63_RS03630 773437 774618 + membrane biogenesis protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03630 AFK63_RS03635 AFK63_03640 AFK63_RS03635 774738 776216 + GTPase Der gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03635 AFK63_RS03640 AFK63_03645 AFK63_RS03640 776267 776488 + hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03640 AFK63_RS03645 AFK63_03650 AFK63_RS03645 776485 776835 - hypothetical protein gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03645 AFK63_RS03650 AFK63_03655 AFK63_RS03650 776835 777860 - peptidase M4 gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03650 AFK63_RS03655 AFK63_03660 xseA xseA 777942 779315 - exodeoxyribonuclease VII large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03655 AFK63_RS03660 AFK63_03665 AFK63_RS03660 779486 780952 + inosine-5-monophosphate dehydrogenase gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03660 AFK63_RS03665 AFK63_03670 guaA guaA 781019 782596 + GMP synthase contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03665 AFK63_RS03670 AFK63_03675 AFK63_RS03670 782904 784094 + integrase gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03670 AFK63_RS03675 AFK63_03680 AFK63_RS03675 784218 784847 + hypothetical protein gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03675 AFK63_RS03680 AFK63_03690 AFK63_RS03680 789000 789794 + conjugal transfer protein TrbJ gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03680 AFK63_RS03685 AFK63_03695 AFK63_RS03685 790272 790520 - hypothetical protein gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03685 AFK63_RS03690 AFK63_03700 AFK63_RS03690 791455 791874 + plasmid maintenance system antidote protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03690 AFK63_RS03695 AFK63_03705 AFK63_RS03695 792154 792387 + hypothetical protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03695 AFK63_RS03700 AFK63_03710 AFK63_RS03700 792393 792737 + hypothetical protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03700 AFK63_RS03705 AFK63_03715 AFK63_RS03705 792885 797768 + damage-inducible protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03705 AFK63_RS03710 AFK63_03720 AFK63_RS03710 797871 798680 - hypothetical protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03710 AFK63_RS03715 AFK63_03725 AFK63_RS03715 800066 802315 + c-di-GMP phosphodiesterase gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03715 AFK63_RS03720 AFK63_03730 AFK63_RS03720 802355 803896 - exopolyphosphatase gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03720 AFK63_RS03725 AFK63_03735 AFK63_RS03725 803900 805960 - polyphosphate kinase gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03725 AFK63_RS03730 AFK63_03740 purN purN 806195 806836 - phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03730 AFK63_RS03735 AFK63_03745 AFK63_RS03735 806836 807873 - phosphoribosylaminoimidazole synthetase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03735 AFK63_RS03740 AFK63_03750 upp upp 808106 808732 + uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03740 AFK63_RS03745 AFK63_03755 AFK63_RS03745 808813 810102 + uracil transporter gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03745 AFK63_RS03750 AFK63_03760 AFK63_RS03750 810223 810900 + DnaA regulatory inactivator Hda controls initiation of DNA replication by inhibiting re-initiation of replication%2C promotes hydrolysis of DnaA-bound ATP gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03750 AFK63_RS03755 AFK63_03765 AFK63_RS03755 810947 811306 - arsenate reductase gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03755 AFK63_RS03760 AFK63_03770 AFK63_RS03760 811318 812784 - hypothetical protein gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03760 AFK63_RS03765 AFK63_03775 AFK63_RS03765 813008 814072 + permease gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03765 AFK63_RS03770 AFK63_03780 bcp bcp 814168 814638 - thiol peroxidase bacterioferritin comigratory protein%3B thiol peroxidase%3B thioredoxin-dependent%3B hydroperoxide peroxidase%3B in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide%3B contains an active site cysteine gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03770 AFK63_RS03775 AFK63_03785 gcvR gcvR 814641 815210 - glycine cleavage system transcriptional antiactivator GcvR negative transcriptional regulator of the gcvTHP operon gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03775 AFK63_RS03780 AFK63_03790 AFK63_RS03780 815358 816236 + 4-hydroxy-tetrahydrodipicolinate synthase gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03780 AFK63_RS03785 AFK63_03795 AFK63_RS03785 816253 817287 + lipoprotein gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03785 AFK63_RS03790 AFK63_03800 AFK63_RS03790 817417 818130 + phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03790 AFK63_RS03795 AFK63_03805 AFK63_RS03795 818262 819122 + hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03795 AFK63_RS03800 AFK63_03810 AFK63_RS03800 819171 821165 + methionine tRNA cytidine acetyltransferase cetylates the wobble base C34 of the elongation-specific methionine tRNA gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03800 AFK63_RS03805 AFK63_03815 AFK63_RS03805 821239 821937 + hydrolase gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03805 AFK63_RS03810 AFK63_03820 AFK63_RS03810 822010 822198 - hypothetical protein gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03810 AFK63_RS03815 AFK63_03825 AFK63_RS03815 822227 823354 - succinyl-diaminopimelate desuccinylase gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03815 AFK63_RS03820 AFK63_03830 AFK63_RS03820 823359 823715 - reductase gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03820 AFK63_RS03825 AFK63_03835 AFK63_RS03825 823820 824251 - acetyltransferase gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03825 AFK63_RS03830 AFK63_03840 AFK63_RS03830 824617 827733 - multidrug efflux RND transporter permease subunit gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03830 AFK63_RS03835 AFK63_03845 AFK63_RS03835 827871 828515 - transcriptional regulator NarP nitrate/nitrite response regulator NarP%3B NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems%3B represses expression of other anaerobic genes gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03835 AFK63_RS03840 AFK63_03850 AFK63_RS03840 828759 829334 + GDP-mannose pyrophosphatase gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03840 AFK63_RS03845 AFK63_03855 AFK63_RS03845 829466 830509 + hypothetical protein gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03845 AFK63_RS03850 AFK63_03860 AFK63_RS03850 830585 831529 + hypothetical protein gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03850 AFK63_RS03855 AFK63_03865 AFK63_RS03855 831988 832167 + hypothetical protein gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03855 AFK63_RS03860 AFK63_03870 AFK63_RS03860 832361 834355 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03860 AFK63_RS03865 AFK63_03875 AFK63_RS03865 834376 835326 - transaldolase gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03865 AFK63_RS03870 AFK63_03880 AFK63_RS03870 835609 837888 + malic enzyme NADP-dependent%3B catalyzes the oxidative decarboxylation of malate to form pyruvate%3B decarboxylates oxaloacetate gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03870 AFK63_RS03875 AFK63_03885 AFK63_RS03875 838077 838868 - iron-enterobactin transporter ATP-binding protein with FepBDE is involved in the transport of ferric enterobactin gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03875 AFK63_RS03880 AFK63_03890 AFK63_RS03880 838865 839857 - iron-enterobactin transporter permease with FepBCD is involved in the transport of ferric enterobactin gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03880 AFK63_RS03885 AFK63_03895 AFK63_RS03885 839854 840861 - iron-enterobactin transporter membrane protein with FepBCG is involved in the transport of ferric enterobactin gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03885 AFK63_RS03890 AFK63_03900 AFK63_RS03890 840969 842213 + enterobactin exporter EntS protein p43%3B inner membrane protein that exports enterobactin to the periplasmic space%3B member of the major facilitator superfamily (MFS) of transporters gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03890 AFK63_RS03895 AFK63_03905 AFK63_RS03895 842240 843199 - iron-enterobactin ABC transporter substrate-binding protein with FepCDG is involved in the transport of ferric enterobactin gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03895 AFK63_RS03900 AFK63_03910 AFK63_RS03900 843387 844556 + isochorismate synthase gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03900 AFK63_RS03905 AFK63_03915 entE entE 844567 846171 + enterobactin synthase subunit E bifunctional 2%2C3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase%3B activates the carboxylate group of 2%2C3-dihydroxy-benzoate forming (2%2C3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2%2C3-dihydroxy-benzoate adenylate gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03905 AFK63_RS03910 AFK63_03920 AFK63_RS03910 846181 847050 + isochorismatase 2%2C3 dihydro-2%2C3 dihydroxybenzoate synthase%3B catalyzes the formation of 2%2C3 dihydro-2%2C3 dihydroxybenzoate and pyruvate from isochorismate%3B with Ent DEF is involved in enterobactin synthesis gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03910 AFK63_RS03915 AFK63_03925 AFK63_RS03915 847047 847799 + 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase catalyzes the formation of 2%2C3-dihydroxybenzoate from 2%2C3-dihydro-2%2C3-dihydroxybenzoate%3B involved in the biosynthesis of siderophores%2C enterobactin%2C bacillibactin or vibriobactin gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03915 AFK63_RS03920 AFK63_03930 AFK63_RS03920 847800 848213 + proofreading thioesterase EntH required for efficient enterobactin production gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03920 AFK63_RS03925 AFK63_03935 AFK63_RS03925 848782 850887 + carbon starvation protein A gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03925 AFK63_RS03930 AFK63_03940 AFK63_RS03930 851045 851242 + hypothetical protein gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03930 AFK63_RS03935 AFK63_03945 AFK63_RS03935 851250 851630 - 2-hydroxyacid dehydrogenase gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03935 AFK63_RS03940 AFK63_03950 AFK63_RS03940 851644 851904 - hypothetical protein gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03940 AFK63_RS03945 AFK63_03955 AFK63_RS03945 852087 853331 - MFS transporter gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03945 AFK63_RS03950 AFK63_03960 AFK63_RS03950 853445 854533 - oxidoreductase member of the iron-containing alcohol dehydrogenase family gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03950 AFK63_RS03955 AFK63_03965 AFK63_RS03955 854796 856301 + ABC transporter gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03955 AFK63_RS03960 AFK63_03970 AFK63_RS03960 856298 857293 + sugar ABC transporter permease gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03960 AFK63_RS03965 AFK63_03975 AFK63_RS03965 857316 858380 + sugar ABC transporter substrate-binding protein gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03965 AFK63_RS03970 AFK63_03980 AFK63_RS03970 858380 859624 + hypothetical protein gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03970 AFK63_RS03975 AFK63_03985 AFK63_RS03975 860374 861573 - methylthioribose kinase gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03975 AFK63_RS03980 AFK63_03990 AFK63_RS03980 861679 862698 + methylthioribose-1-phosphate isomerase gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03980 AFK63_RS03985 AFK63_03995 AFK63_RS03985 862732 863634 - coproporphyrinogen III oxidase catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03985 AFK63_RS03990 AFK63_04000 AFK63_RS03990 863637 864512 - N-acetylmuramoyl-L-alanine amidase gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03990 AFK63_RS03995 AFK63_04005 AFK63_RS03995 864727 865152 + acetyltransferase gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS03995 AFK63_RS04000 AFK63_04010 AFK63_RS04000 865191 865589 - hypothetical protein gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04000 AFK63_RS04005 AFK63_04015 AFK63_RS04005 865689 866123 + membrane protein gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04005 AFK63_RS04010 AFK63_04020 AFK63_RS04010 866185 866769 + RpoE-regulated lipoprotein gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04010 AFK63_RS04015 AFK63_04025 AFK63_RS04015 866860 867762 + peroxidase gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04015 AFK63_RS04020 AFK63_04030 AFK63_RS04020 867922 868938 + thiosulfate transporter subunit gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04020 AFK63_RS04025 AFK63_04035 AFK63_RS04025 868938 869768 + sulfate/thiosulfate transporter subunit gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04025 AFK63_RS04030 AFK63_04040 cysW cysW 869768 870637 + sulfate/thiosulfate transporter permease subunit Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04030 AFK63_RS04035 AFK63_04045 AFK63_RS04035 870627 871721 + sulfate/thiosulfate transporter subunit gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04035 AFK63_RS04040 AFK63_04050 cysM cysM 871839 872750 + cysteine synthase catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04040 AFK63_RS04045 AFK63_04055 AFK63_RS04045 872780 873304 - hypothetical protein gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04045 AFK63_RS04050 AFK63_04060 AFK63_RS04050 873379 873882 - PTS glucose transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04050 AFK63_RS04055 AFK63_04065 AFK63_RS04055 873926 875653 - phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04055 AFK63_RS04060 AFK63_04070 AFK63_RS04060 875697 875954 - phosphocarrier protein HPr gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04060 AFK63_RS04065 AFK63_04075 AFK63_RS04065 876340 877311 - cysteine synthase gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04065 AFK63_RS04070 AFK63_04080 AFK63_RS04070 877458 878219 - sulfate transporter gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04070 AFK63_RS04075 AFK63_04085 AFK63_RS04075 878450 879403 + cell division protein ZipA gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04075 AFK63_RS04080 AFK63_04090 ligA ligA 879473 881491 + NAD-dependent DNA ligase LigA this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04080 AFK63_RS04085 AFK63_04095 AFK63_RS04085 881493 881708 + hypothetical protein gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04085 AFK63_RS04090 AFK63_04100 AFK63_RS04090 881790 882122 - FlxA protein gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04090 AFK63_RS04095 AFK63_04105 AFK63_RS04095 882467 882542 - tRNA-Lys tRNA gene818 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04095 AFK63_RS04100 AFK63_04110 AFK63_RS04100 882547 882622 - tRNA-Val tRNA gene819 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04100 AFK63_RS04105 AFK63_04115 AFK63_RS04105 882672 882747 - tRNA-Val tRNA gene820 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04105 AFK63_RS04110 AFK63_04120 AFK63_RS04110 882792 882867 - tRNA-Val tRNA gene821 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04110 AFK63_RS04115 AFK63_04125 gltX gltX 883128 884543 + glutamate--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04115 AFK63_RS04120 AFK63_04130 AFK63_RS04120 884570 884959 - negative regulator gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04120 AFK63_RS04125 AFK63_04135 AFK63_RS04125 884963 885322 - hypothetical protein gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04125 AFK63_RS04130 AFK63_04140 AFK63_RS04130 885542 885617 + tRNA-Ala tRNA gene825 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04130 AFK63_RS04135 AFK63_04145 AFK63_RS04135 885662 885737 + tRNA-Ala tRNA gene826 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04135 AFK63_RS04140 AFK63_04150 AFK63_RS04140 885921 888104 + hypothetical protein gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04140 AFK63_RS04145 AFK63_04155 AFK63_RS04145 888150 889334 - nucleoside permease gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04145 AFK63_RS04150 AFK63_04160 AFK63_RS04150 889690 890928 + manganese transporter MntH gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04150 AFK63_RS04155 AFK63_04165 AFK63_RS04155 890984 891346 - hypothetical protein gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04155 AFK63_RS04160 AFK63_04170 AFK63_RS04160 891483 892472 - glyceraldehyde 3-phosphate reductase gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04160 AFK63_RS04165 AFK63_04175 AFK63_RS04165 892692 894359 + indolepyruvate decarboxylase thiamindiphosphate-dependent%3B catalyzes the formation of indoleacetaldehyde from indolepyruvate gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04165 AFK63_RS04170 AFK63_04180 glk glk 894513 895478 + glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04170 AFK63_RS04175 AFK63_04185 AFK63_RS04175 895515 896246 - two-component system response regulator gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04175 AFK63_RS04180 AFK63_04190 AFK63_RS04180 896259 897950 - membrane protein gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04180 AFK63_RS04185 AFK63_04195 AFK63_RS04185 898030 899271 - hypothetical protein gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04185 AFK63_RS04190 AFK63_04200 AFK63_RS04190 899513 900754 + glutamate--pyruvate aminotransferase gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04190 AFK63_RS04195 AFK63_04205 AFK63_RS04195 901215 901571 + cupin gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04195 AFK63_RS04200 AFK63_04210 AFK63_RS04200 901549 902517 - magnesium transporter CorA gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04200 AFK63_RS04205 AFK63_04215 AFK63_RS04205 902613 903485 - transcriptional regulator gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04205 AFK63_RS04210 AFK63_04220 AFK63_RS04210 903592 904371 + alpha-acetolactate decarboxylase gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04210 AFK63_RS04215 AFK63_04225 AFK63_RS04215 904393 906072 + acetolactate synthase gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04215 AFK63_RS04220 AFK63_04230 AFK63_RS04220 906093 906863 + acetoin reductase gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04220 AFK63_RS04225 AFK63_04235 AFK63_RS04225 906975 907334 + hypothetical protein gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04225 AFK63_RS04230 AFK63_04240 AFK63_RS04230 907454 908149 - hypothetical protein gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04230 AFK63_RS04235 AFK63_04245 AFK63_RS04235 908395 908841 - hypothetical protein gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04235 AFK63_RS04240 AFK63_04250 AFK63_RS04240 908956 909390 - hypothetical protein gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04240 AFK63_RS04245 AFK63_04255 AFK63_RS04245 909550 909783 - hypothetical protein gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04245 AFK63_RS04250 AFK63_04260 AFK63_RS04250 910121 911041 - LysR family transcriptional regulator gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04250 AFK63_RS04255 AFK63_04265 AFK63_RS04255 911280 912608 + D-galactonate transporter gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04255 AFK63_RS04260 AFK63_04270 AFK63_RS04260 912660 913409 + short-chain dehydrogenase gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04260 AFK63_RS04265 AFK63_04275 AFK63_RS04265 913425 914258 + transketolase gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04265 AFK63_RS04270 AFK63_04280 AFK63_RS04270 914269 915267 + transketolase gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04270 AFK63_RS04275 AFK63_04285 AFK63_RS04275 915413 915847 - hypothetical protein gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04275 AFK63_RS04280 AFK63_04290 AFK63_RS04280 917118 917936 + CAAX amino protease gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04280 AFK63_RS04285 AFK63_04295 AFK63_RS04285 918012 918428 - hypothetical protein gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04285 AFK63_RS04290 AFK63_04300 AFK63_RS04290 918964 919038 - tRNA-Arg tRNA gene857 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04290 AFK63_RS04295 AFK63_04305 AFK63_RS04295 919115 920065 - membrane protein gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04295 AFK63_RS04300 AFK63_04310 AFK63_RS04300 920266 920883 + cytochrome C biogenesis protein CcmA ATP-binding protein%3B required for proper cytochrome c maturation gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04300 AFK63_RS04305 AFK63_04315 AFK63_RS04305 920880 921539 + heme ABC transporter permease with CcmABCE is involved in the transport of protoheme IX%3B CcmB is required for the release of holoCcmE from CcmC gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04305 AFK63_RS04310 AFK63_04320 AFK63_RS04310 921580 922332 + heme ABC transporter permease with CcmABDE is involved in the transport of protoheme IX%3B CcmC is required for heme transfer to CcmE gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04310 AFK63_RS04315 AFK63_04325 AFK63_RS04315 922317 922523 + cytochrome C biogenesis protein CcmD is invovled in heme transfer during cytochrome c biogenesis%3B acts to stabilize CcmC and CcmE gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04315 AFK63_RS04320 AFK63_04330 AFK63_RS04320 922520 922999 + cytochrome C biogenesis protein CcmE CycJ%3B periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes%3B requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome%3B part of the cytochrome c maturation system%3B periplasmic protein anchored to the inner membrane gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04320 AFK63_RS04325 AFK63_04335 AFK63_RS04325 922996 924954 + cytochrome C biogenesis protein CcmF cytochrome c-type biogenesis protein%3B required for the transfer of heme to apocytochrome c gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04325 AFK63_RS04330 AFK63_04340 AFK63_RS04330 924951 925508 + thiol:disulfide interchange protein DsbE cytochrome c-type biogenesis thioredoxin%3B involved in the reduction of disulfide bonds to allow heme bonding gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04330 AFK63_RS04335 AFK63_04345 AFK63_RS04335 925505 925966 + cytochrome C gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04335 AFK63_RS04340 AFK63_04350 AFK63_RS04340 925963 927162 + cytochrome C gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04340 AFK63_RS04345 AFK63_04355 AFK63_RS04345 927186 927941 + ABC transporter permease involved in maintaining OM lipid asymmetry gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04345 AFK63_RS04350 AFK63_04360 AFK63_RS04350 928079 929440 - long-chain fatty acid outer membrane transporter gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04350 AFK63_RS04355 AFK63_04365 AFK63_RS04355 929799 930083 + hypothetical protein gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04355 AFK63_RS04360 AFK63_04370 fadI fadI 930251 931561 + 3-ketoacyl-CoA thiolase FadI%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadJ%3B similar to FadA2B2 complex%3B functions in beta-oxidation of fatty acids during anaerobic growth gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04360 AFK63_RS04365 AFK63_04375 fadJ fadJ 931561 933714 + multifunctional fatty acid oxidation complex subunit alpha multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI%3B similar to FadA2B2 complex%3B involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04365 AFK63_RS04370 AFK63_04380 AFK63_RS04370 933920 934408 + phosphohistidine phosphatase gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04370 AFK63_RS04375 AFK63_04385 AFK63_RS04375 934503 935054 - hypothetical protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04375 AFK63_RS04380 AFK63_04390 AFK63_RS04380 935216 936148 + ribosomal protein L3 methyltransferase involved in methylation of ribosomal protein L3 gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04380 AFK63_RS04385 AFK63_04395 AFK63_RS04385 936213 937298 + chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04385 AFK63_RS04390 AFK63_04400 mepA mepA 937303 938127 + murein endopeptidase D-alanyl-D-alanine endopeptidase%3B functions in hydrolyzing cell wall peptidoglycan%3B similar to LAS metallopeptidases%3B forms a dimer in periplasm gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04390 AFK63_RS04395 AFK63_04405 AFK63_RS04395 938146 938943 + hypothetical protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04395 AFK63_RS04400 AFK63_04410 AFK63_RS04400 938943 939488 + elongation factor P hydroxylase gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04400 AFK63_RS04405 AFK63_04415 AFK63_RS04405 939517 939795 + hypothetical protein gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04405 AFK63_RS04410 AFK63_04420 mnmC mnmC 940123 942135 - FAD-dependent oxidoreductase 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase/FAD-dependent demodification enzyme gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04410 AFK63_RS04415 AFK63_04425 AFK63_RS04415 942292 943509 + 3-oxoacyl-ACP synthase FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04415 AFK63_RS04420 AFK63_04430 AFK63_RS04420 944076 946850 + serine protease gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04420 AFK63_RS04425 AFK63_04435 flk flk 946905 947909 - flagella biosynthesis regulator in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system%3B lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm%3B inner membrane-anchored protein gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04425 AFK63_RS04430 AFK63_04440 AFK63_RS04430 948032 949168 + erythronate-4-phosphate dehydrogenase catalyzes the formation of 3-hydroxy-2-oxo-4-phosphonooxybutanoate from erythronate-4-phosphate gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04430 AFK63_RS04435 AFK63_04445 AFK63_RS04435 949238 950251 + semialdehyde dehydrogenase gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04435 AFK63_RS04440 AFK63_04450 truA truA 950251 951063 + tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04440 AFK63_RS04445 AFK63_04455 AFK63_RS04445 951089 951748 + hypothetical protein gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04445 AFK63_RS04450 AFK63_04460 AFK63_RS04450 951899 952819 + acetyl-CoA carboxylase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04450 AFK63_RS04455 AFK63_04465 AFK63_RS04455 952890 954158 + bifunctional folylpolyglutamate synthase/ dihydrofolate synthase gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04455 AFK63_RS04460 AFK63_04470 AFK63_RS04460 954148 954870 + cell division protein DedD gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04460 AFK63_RS04465 AFK63_04475 AFK63_RS04465 955103 955588 + colicin V production protein membrane protein required for colicin V production gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04465 AFK63_RS04470 AFK63_04480 AFK63_RS04470 955628 957145 + amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04470 AFK63_RS04475 AFK63_04485 AFK63_RS04475 957258 957827 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04475 AFK63_RS04480 AFK63_04490 AFK63_RS04480 958105 958887 + histidine ABC transporter substrate-binding protein HisJ with HisPMQ is involved in the transport of histidine gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04480 AFK63_RS04485 AFK63_04495 AFK63_RS04485 959123 959905 + histidine ABC transporter substrate-binding protein HisJ with HisPMQ is involved in the transport of histidine gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04485 AFK63_RS04490 AFK63_04500 AFK63_RS04490 959979 960665 + amino acid ABC transporter permease with HisJMP is involved in the transport of histidine/lysine/arginine/ornithine gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04490 AFK63_RS04495 AFK63_04505 AFK63_RS04495 960662 961378 + amino acid ABC transporter permease with HisJPQ is involved in transport of histidine%2C lysine%2C arginine and ornithine gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04495 AFK63_RS04500 AFK63_04510 AFK63_RS04500 961389 962162 + histidine ABC transporter ATP-binding protein gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04500 AFK63_RS04505 AFK63_04515 AFK63_RS04505 962206 962850 - hypothetical protein gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04505 AFK63_RS04510 AFK63_04520 AFK63_RS04510 962843 963541 - hypothetical protein gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04510 AFK63_RS04515 AFK63_04525 AFK63_RS04515 963670 964572 - epimerase gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04515 AFK63_RS04520 AFK63_04530 AFK63_RS04520 964776 965405 - glutathione S-transferase gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04520 AFK63_RS04525 AFK63_04535 AFK63_RS04525 965550 966194 + glutathione S-transferase catalyzes the formation of 2%2C4-dinitrophenyl-S-glutathione from 1-chloro-2%2C4-dinitrobenzene and glutathione gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04525 AFK63_RS04530 AFK63_04540 AFK63_RS04530 966254 966805 + phosphodiesterase gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04530 AFK63_RS04535 AFK63_04545 AFK63_RS04535 966860 967426 + NUDIX hydrolase gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04535 AFK63_RS04540 AFK63_04550 AFK63_RS04540 967485 968069 - TetR family transcriptional regulator gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04540 AFK63_RS04545 AFK63_04555 AFK63_RS04545 968347 968694 + transcriptional regulator gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04545 AFK63_RS04550 AFK63_04560 AFK63_RS04550 968760 969008 + membrane protein gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04550 AFK63_RS04555 AFK63_04565 AFK63_RS04555 969073 971211 - phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04555 AFK63_RS04560 AFK63_04570 AFK63_RS04560 971295 972497 - acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04560 AFK63_RS04565 AFK63_04575 AFK63_RS04565 972832 973287 + hypothetical protein gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04565 AFK63_RS04570 AFK63_04580 AFK63_RS04570 973375 973869 + hypothetical protein gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04570 AFK63_RS04575 AFK63_04585 AFK63_RS04575 973882 974541 + phosphatase gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04575 AFK63_RS04580 AFK63_04590 AFK63_RS04580 974642 976474 + citrate transporter gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04580 AFK63_RS04585 AFK63_04595 AFK63_RS04585 976479 977078 - 5'-nucleotidase gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04585 AFK63_RS04590 AFK63_04600 AFK63_RS04590 977159 978373 - aminotransferase broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04590 AFK63_RS04595 AFK63_04605 AFK63_RS04595 979324 980259 + transcriptional regulator gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04595 AFK63_RS04600 AFK63_04610 AFK63_RS04600 980879 981328 + NADH-quinone oxidoreductase subunit A gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04600 AFK63_RS04605 AFK63_04615 AFK63_RS04605 981344 982018 + NADH-quinone oxidoreductase subunit B gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04605 AFK63_RS04610 AFK63_04620 AFK63_RS04610 982118 983917 + NADH:ubiquinone oxidoreductase NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04610 AFK63_RS04615 AFK63_04625 AFK63_RS04615 983920 984420 + NADH dehydrogenase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04615 AFK63_RS04620 AFK63_04630 AFK63_RS04620 984417 985754 + NADH dehydrogenase part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04620 AFK63_RS04625 AFK63_04635 AFK63_RS04625 985809 988535 + NADH dehydrogenase Catalyzes the transfer of electrons from NADH to quinone gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04625 AFK63_RS04630 AFK63_04640 AFK63_RS04630 988532 989512 + NADH:ubiquinone oxidoreductase gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04630 AFK63_RS04635 AFK63_04645 AFK63_RS04635 989527 990069 + NADH-ubiquinone oxidoreductase chain I gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04635 AFK63_RS04640 AFK63_04650 AFK63_RS04640 990080 990643 + NADH:ubiquinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04640 AFK63_RS04645 AFK63_04655 AFK63_RS04645 990640 990942 + NADH-quinone oxidoreductase subunit K gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04645 AFK63_RS04650 AFK63_04660 AFK63_RS04650 990939 992780 + NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04650 AFK63_RS04655 AFK63_04665 AFK63_RS04655 992950 994479 + NADH:ubiquinone oxidoreductase subunit M gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04655 AFK63_RS04660 AFK63_04670 AFK63_RS04660 994486 995961 + NADH:ubiquinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04660 AFK63_RS04665 AFK63_04675 AFK63_RS04665 996017 996931 - ribonuclease Z RNase BN%3B member of metallo-beta-lactamase family%3B the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase%3B in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not%3B associates with two zinc ions gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04665 AFK63_RS04670 AFK63_04680 AFK63_RS04670 997005 997475 + acyltransferase gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04670 AFK63_RS04675 AFK63_04685 AFK63_RS04675 997525 997836 + protein ElaB gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04675 AFK63_RS04680 AFK63_04690 AFK63_RS04680 997937 999211 + isochorismate synthase gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04680 AFK63_RS04685 AFK63_04695 AFK63_RS04685 999297 1000964 + 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase SEPHCHC synthase%3B forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04685 AFK63_RS04690 AFK63_04700 AFK63_RS04690 1000964 1001755 + 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase catalyzes the formation of (1 R%2C6 R)-2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04690 AFK63_RS04695 AFK63_04705 AFK63_RS04695 1001742 1002599 + dihydroxynaphthoic acid synthetase catalyzes the formation of 1%2C4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04695 AFK63_RS04700 AFK63_04710 AFK63_RS04700 1002599 1003564 + O-succinylbenzoate synthase catalyzes the dehydration of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04700 AFK63_RS04705 AFK63_04715 AFK63_RS04705 1003561 1004952 + O-succinylbenzoic acid--CoA ligase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04705 AFK63_RS04710 AFK63_04720 AFK63_RS04710 1004929 1005552 - hypothetical protein gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04710 AFK63_RS04715 AFK63_04725 AFK63_RS04715 1005657 1007174 - tripartite tricarboxylate transporter TctA gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04715 AFK63_RS04720 AFK63_04730 AFK63_RS04720 1007186 1007617 - membrane protein gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04720 AFK63_RS04725 AFK63_04735 AFK63_RS04725 1007632 1008612 - tricarboxylic transport membrane protein gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04725 AFK63_RS04730 AFK63_04740 AFK63_RS04730 1008746 1009426 + two-component system response regulator transcriptional activator of tricarboxylate transport system genes gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04730 AFK63_RS04735 AFK63_04745 AFK63_RS04735 1009407 1010843 + histidine kinase gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04735 AFK63_RS04740 AFK63_04750 AFK63_RS04740 1010986 1011528 + membrane protein gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04740 AFK63_RS04745 AFK63_04755 AFK63_RS04745 1011621 1012817 + hypothetical protein gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04745 AFK63_RS04750 AFK63_04760 glpT glpT 1013149 1014501 + sn-glycerol-3-phosphate transporter catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04750 AFK63_RS04755 AFK63_04765 glpQ glpQ 1014511 1015566 + glycerophosphodiester phosphodiesterase hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols%3B periplasmic gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04755 AFK63_RS04760 AFK63_04770 AFK63_RS04760 1015704 1015958 - Ferredoxin plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor%2C essential for nucleotide reduction catalyzed by ribonucleotide reductases gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04760 AFK63_RS04765 AFK63_04775 AFK63_RS04765 1015960 1017090 - ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04765 AFK63_RS04770 AFK63_04780 AFK63_RS04770 1017249 1019534 - ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04770 AFK63_RS04775 AFK63_04785 AFK63_RS04775 1019875 1020606 - 3-demethylubiquinone-9 3-methyltransferase Involved in ubiquinone biosynthesis gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04775 AFK63_RS04780 AFK63_04790 AFK63_RS04780 1020766 1023402 + DNA gyrase subunit A gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04780 AFK63_RS04785 AFK63_04795 AFK63_RS04785 1023598 1026447 + histidine kinase gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04785 AFK63_RS04790 AFK63_04800 AFK63_RS04790 1026611 1027261 - transcriptional regulator two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division%3B probably phosphorylated by RcsC or RcsF gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04790 AFK63_RS04795 AFK63_04805 AFK63_RS04795 1027278 1029932 - phosphotransfer intermediate protein in two-component regulatory system with RcsBC gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04795 AFK63_RS04800 AFK63_04810 AFK63_RS04800 1030773 1031915 + membrane protein gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04800 AFK63_RS04805 AFK63_04815 AFK63_RS04805 1032012 1033055 + thiamine biosynthesis protein ApbE catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine%3B involved in the maintenance and/or assembly of sulfur clusters%3B periplasmic lipoporotein anchored to the inner membrane%3B part of the thiamine pyrophosphate biosynthesis pathway gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04805 AFK63_RS04810 AFK63_04820 AFK63_RS04810 1033128 1034192 + 6-O-methylguanine DNA methyltransferase regulates genes involved in the repair of alkylated DNA%3B repairs DNA containing 6-O-methylguanine gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04810 AFK63_RS04815 AFK63_04825 AFK63_RS04815 1034192 1034836 + alpha-ketoglutarate-dependent dioxygenase gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04815 AFK63_RS04820 AFK63_04830 AFK63_RS04820 1034916 1036562 + multidrug transporter membrane component/ATP-binding protein efflux pump for the antibacterial peptide microcin J25 gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04820 AFK63_RS04825 AFK63_04835 AFK63_RS04825 1036640 1038133 - transporter gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04825 AFK63_RS04830 AFK63_04840 AFK63_RS04830 1038242 1039759 - transcriptional regulator Required for the expression of anaerobic nitric oxide (NO) reductase%3B acts as a transcriptional activator for the norVW operon gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04830 AFK63_RS04835 AFK63_04845 AFK63_RS04835 1039917 1041347 + nitric oxide reductase detoxifies nitric oxide using NADH gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04835 AFK63_RS04840 AFK63_04850 AFK63_RS04840 1041351 1042493 + NADH:flavorubredoxin oxidoreductase gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04840 AFK63_RS04845 AFK63_04855 AFK63_RS04845 1042498 1042710 - hypothetical protein gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04845 AFK63_RS04850 AFK63_04860 AFK63_RS04850 1042801 1043148 + hypothetical protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04850 AFK63_RS04855 AFK63_04865 AFK63_RS04855 1043375 1045645 + restriction endonuclease subunit M gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04855 AFK63_RS04860 AFK63_04870 AFK63_RS04860 1045645 1046955 + hypothetical protein gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04860 AFK63_RS04865 AFK63_04875 AFK63_RS04865 1046952 1050218 + type I restriction endonuclease subunit R gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04865 AFK63_RS04870 AFK63_04880 AFK63_RS04870 1050230 1051003 - AraC family transcriptional regulator gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04870 AFK63_RS04875 AFK63_04885 AFK63_RS04875 1051120 1051848 + glutamine amidotransferase Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04875 AFK63_RS04880 AFK63_04890 AFK63_RS04880 1051914 1052543 - glutathione S-transferase gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04880 AFK63_RS04885 AFK63_04895 AFK63_RS04885 1052971 1053540 + outer membrane protein gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04885 AFK63_RS04890 AFK63_04900 AFK63_RS04890 1053735 1053811 - tRNA-Pro tRNA gene977 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04890 AFK63_RS04895 AFK63_04905 AFK63_RS04895 1053886 1055649 - membrane protein gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04895 AFK63_RS04900 AFK63_04910 AFK63_RS04900 1055669 1055896 - hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04900 AFK63_RS04905 AFK63_04915 AFK63_RS04905 1056031 1057035 + nucleoid-associated protein gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04905 AFK63_RS04910 AFK63_04920 AFK63_RS04910 1057134 1057418 - 50S ribosomal protein L25 the Ctc family of proteins consists of two types%2C one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04910 AFK63_RS04915 AFK63_04925 AFK63_RS04915 1057545 1059305 - hypothetical protein gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04915 AFK63_RS04920 AFK63_04930 AFK63_RS04920 1059493 1060200 + 16S rRNA pseudouridylate synthase catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04920 AFK63_RS04925 AFK63_04935 AFK63_RS04925 1060216 1061412 + Bcr/CflA family drug resistance efflux transporter Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04925 AFK63_RS04930 AFK63_04940 AFK63_RS04930 1061747 1062091 + hypothetical protein gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04930 AFK63_RS04935 AFK63_04945 AFK63_RS04935 1062095 1063684 - microcin ABC transporter ATP-binding protein with YejAEF is involved in resistance to microcin C gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04935 AFK63_RS04940 AFK63_04950 AFK63_RS04940 1063686 1064711 - microcin ABC transporter permease part of the microcin C transport system gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04940 AFK63_RS04945 AFK63_04955 AFK63_RS04945 1064708 1065808 - microcin ABC transporter permease with YejAEF is involved in resistance to microcin C gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04945 AFK63_RS04950 AFK63_04960 AFK63_RS04950 1065817 1067622 - antibiotic ABC transporter substrate-binding protein with YejBEF is involved in resistance to microcin C gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04950 AFK63_RS04955 AFK63_04965 AFK63_RS04955 1067718 1069280 - phage resistance protein involved in resistance to the phages N4 and lambda gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04955 AFK63_RS04960 AFK63_04970 spr spr 1069447 1070016 - membrane protein mutational suppressor of prc thermosensitivity gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04960 AFK63_RS04965 AFK63_04975 AFK63_RS04965 1070442 1071149 - membrane protein gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04965 AFK63_RS04970 AFK63_04980 AFK63_RS04970 1071181 1072167 - hypothetical protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04970 AFK63_RS04975 AFK63_04985 AFK63_RS04975 1072298 1073764 - D-mannonate oxidoreductase gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04975 AFK63_RS04980 AFK63_04990 AFK63_RS04980 1073971 1075161 + mannonate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04980 AFK63_RS04985 AFK63_04995 AFK63_RS04985 1075228 1075800 - elongation factor P-like protein Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro%2C suggesting its involvement in the formation of the first peptide bond of a protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04985 AFK63_RS04990 AFK63_05000 AFK63_RS04990 1075994 1076437 + acetyltransferase gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04990 AFK63_RS04995 AFK63_05005 AFK63_RS04995 1076458 1076712 + hypothetical protein gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS04995 AFK63_RS05000 AFK63_05010 AFK63_RS05000 1076709 1077890 - sugar transporter gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05000 AFK63_RS05005 AFK63_05015 AFK63_RS05005 1078259 1079392 + bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein phosphoenolpyruvate (PEP)-dependent%2C sugar transporting phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05005 AFK63_RS05010 AFK63_05020 fruK fruK 1079389 1080327 + 1-phosphofructokinase converts fructose-1-phosphate and ATP to fructose-1%2C6-bisphosphate and ADP%3B highly specific for fructose-1-phopshate%3B similar to PfkB%3B forms homodimers gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05010 AFK63_RS05015 AFK63_05025 AFK63_RS05015 1080344 1082050 + PTS fructose transporter subunits IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05015 AFK63_RS05020 AFK63_05030 AFK63_RS05020 1082181 1082996 + xylose isomerase gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05020 AFK63_RS05025 AFK63_05035 AFK63_RS05025 1083009 1083869 - endonuclease 4 gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05025 AFK63_RS05030 AFK63_05040 AFK63_RS05030 1083943 1084992 - membrane protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05030 AFK63_RS05035 AFK63_05045 AFK63_RS05035 1085109 1085975 + transcriptional regulator gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05035 AFK63_RS05040 AFK63_05050 AFK63_RS05040 1086162 1087631 + lysine transporter gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05040 AFK63_RS05045 AFK63_05055 AFK63_RS05045 1087725 1088555 - S-formylglutathione hydrolase gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05045 AFK63_RS05050 AFK63_05060 AFK63_RS05050 1088679 1089803 + MFS transporter gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05050 AFK63_RS05055 AFK63_05065 folE folE 1089929 1090600 + GTP cyclohydrolase I involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05055 AFK63_RS05060 AFK63_05070 AFK63_RS05060 1090610 1091767 + hypothetical protein gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05060 AFK63_RS05065 AFK63_05075 AFK63_RS05065 1091923 1092948 + transcriptional regulator controls transcription of galETKM gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05065 AFK63_RS05070 AFK63_05080 AFK63_RS05070 1093231 1094226 + sugar ABC transporter substrate-binding protein wtih MglAC is involved in the transport of beta-methylgalactoside gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05070 AFK63_RS05075 AFK63_05085 AFK63_RS05075 1094313 1095833 + sugar ABC transporter ATP-binding protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05075 AFK63_RS05080 AFK63_05090 mglC mglC 1095849 1096859 + beta-methylgalactoside transporter permease ABC transporter%3B functions in galactose transport%3B part of MglA2C2B transporter complex gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05080 AFK63_RS05085 AFK63_05095 AFK63_RS05085 1097032 1097745 - vancomycin high temperature exclusion protein involved in vancomycin sensitivity and other barrier functions of the cell envelope gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05085 AFK63_RS05090 AFK63_05100 AFK63_RS05090 1097870 1098754 - cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05090 AFK63_RS05095 AFK63_05105 AFK63_RS05095 1098883 1099578 - hypothetical protein gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05095 AFK63_RS05100 AFK63_05110 AFK63_RS05100 1099575 1099976 - hypothetical protein gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05100 AFK63_RS05105 AFK63_05115 AFK63_RS05105 1100168 1101100 + tRNA-dihydrouridine synthase C gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05105 AFK63_RS05110 AFK63_05120 AFK63_RS05110 1101087 1102025 - LysR family transcriptional regulator gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05110 AFK63_RS05115 AFK63_05125 AFK63_RS05115 1102101 1103057 + MBL fold metallo-hydrolase gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05115 AFK63_RS05120 AFK63_05130 AFK63_RS05120 1103351 1104127 + oxidoreductase gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05120 AFK63_RS05125 AFK63_05135 AFK63_RS05125 1104124 1104690 - membrane protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05125 AFK63_RS05130 AFK63_05140 AFK63_RS05130 1104875 1105462 + membrane protein gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05130 AFK63_RS05135 AFK63_05145 pbpG pbpG 1105629 1106561 + D-alanyl-D-alanine endopeptidase specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi%3B Penicillin-binding protein 7 gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05135 AFK63_RS05140 AFK63_05150 AFK63_RS05140 1106563 1107117 - GCN5 family acetyltransferase gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05140 AFK63_RS05145 AFK63_05155 AFK63_RS05145 1107210 1108961 - lactate dehydrogenase component of the membrane-bound D-lactate oxidase%2C FAD-binding%2C NADH independent gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05145 AFK63_RS05150 AFK63_05160 AFK63_RS05150 1109155 1111452 + beta-D-glucoside glucohydrolase catalyzes the hydrolysis of terminal beta-D-glucosyl residues gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05150 AFK63_RS05155 AFK63_05165 AFK63_RS05155 1111609 1112517 + osmoprotectant uptake system substrate-binding protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05155 AFK63_RS05160 AFK63_05170 AFK63_RS05160 1112514 1113704 + osmoprotectant uptake system permease gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05160 AFK63_RS05165 AFK63_05175 AFK63_RS05165 1113697 1114638 + ATP-binding protein gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05165 AFK63_RS05170 AFK63_05180 AFK63_RS05170 1114631 1115362 + osmoprotectant uptake system permease gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05170 AFK63_RS05175 AFK63_05185 AFK63_RS05175 1115510 1116253 - transcriptional regulator gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05175 AFK63_RS05180 AFK63_05190 metG metG 1116447 1118480 - methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05180 AFK63_RS05185 AFK63_05195 AFK63_RS05185 1119174 1120391 + hypothetical protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05185 AFK63_RS05190 AFK63_05200 AFK63_RS05190 1120415 1121803 + chemotaxis protein CheY gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05190 AFK63_RS05195 AFK63_05205 AFK63_RS05195 1122178 1123287 + antiporter gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05195 AFK63_RS05200 AFK63_05210 AFK63_RS05200 1123333 1123764 - GCN5 family acetyltransferase gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05200 AFK63_RS05205 AFK63_05215 AFK63_RS05205 1123879 1125564 + histidine kinase gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05205 AFK63_RS05210 AFK63_05220 AFK63_RS05210 1125561 1126286 + two-component system response regulator unknown function%3B when overproduced it confers drug-resistance gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05210 AFK63_RS05215 AFK63_05225 AFK63_RS05215 1126397 1127941 + chemotaxis protein gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05215 AFK63_RS05220 AFK63_05230 AFK63_RS05220 1129136 1129741 + hypothetical protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05220 AFK63_RS05225 AFK63_05235 AFK63_RS05225 1129818 1131545 - ABC transporter gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05225 AFK63_RS05230 AFK63_05240 AFK63_RS05230 1131896 1132222 - nickel/cobalt efflux protein RcnB gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05230 AFK63_RS05235 AFK63_05245 AFK63_RS05235 1132865 1133050 - hypothetical protein gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05235 AFK63_RS05240 AFK63_05255 AFK63_RS05240 1136455 1137252 + hydroxyethylthiazole kinase gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05240 AFK63_RS05245 AFK63_05260 AFK63_RS05245 1137239 1138039 + hydroxymethylpyrimidine kinase catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05245 AFK63_RS05250 AFK63_05265 AFK63_RS05250 1138185 1139237 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1%2C6-bisphosphate gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05250 AFK63_RS05255 AFK63_05270 AFK63_RS05255 1139697 1140596 - lipid kinase cytosolic protein with phosphatidylglycerol kinase activity%3B undetermined physiological role gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05255 AFK63_RS05260 AFK63_05275 AFK63_RS05260 1140847 1142208 - protease gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05260 AFK63_RS05265 AFK63_05280 AFK63_RS05265 1142585 1143307 - two-component system response regulator response regulator in two-component regulatory system with BaeS%3B regulator of RNA synthesis%2C flagellar biosynthesis%2C chemotaxis and transport gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05265 AFK63_RS05270 AFK63_05285 AFK63_RS05270 1143304 1144728 - histidine kinase gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05270 AFK63_RS05275 AFK63_05290 AFK63_RS05275 1144725 1146140 - transporter gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05275 AFK63_RS05280 AFK63_05295 AFK63_RS05280 1146144 1149233 - multidrug transporter Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05280 AFK63_RS05285 AFK63_05300 AFK63_RS05285 1149234 1152356 - multidrug transporter Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05285 AFK63_RS05290 AFK63_05305 AFK63_RS05290 1152356 1153597 - multidrug transporter gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05290 AFK63_RS05295 AFK63_05310 AFK63_RS05295 1153828 1154193 + toxin RelE gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05295 AFK63_RS05300 AFK63_05315 AFK63_RS05300 1154180 1154476 + transcriptional regulator gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05300 AFK63_RS05305 AFK63_05320 AFK63_RS05305 1154482 1155834 - chaperone gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05305 AFK63_RS05310 AFK63_05325 AFK63_RS05310 1155971 1156819 + 3-methyladenine DNA glycosylase inducible%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine and 7-methyladenine gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05310 AFK63_RS05315 AFK63_05330 AFK63_RS05315 1156809 1160147 - diguanylate cyclase gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05315 AFK63_RS05320 AFK63_05335 AFK63_RS05320 1160499 1161140 + uridine kinase gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05320 AFK63_RS05325 AFK63_05340 AFK63_RS05325 1161224 1161805 + deoxycytidine triphosphate deaminase gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05325 AFK63_RS05330 AFK63_05345 AFK63_RS05330 1161836 1163677 + assembly protein YegA%3B inner membrane protein involved in the assembly of outer membrane proteins (OMPs)%3B asmA-null mutants show low lipopolysaccharide (LPS) levels%2C suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity%2C resulting on altered assembly of OMPs gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05330 AFK63_RS05335 AFK63_05350 AFK63_RS05335 1163729 1165318 - membrane protein gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05335 AFK63_RS05340 AFK63_05355 AFK63_RS05340 1166144 1167190 + polysaccharide export protein Wza required for the translocation of capsular polysaccharide through the outer membrane gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05340 AFK63_RS05345 AFK63_05360 AFK63_RS05345 1167196 1167639 + protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05345 AFK63_RS05350 AFK63_05365 AFK63_RS05350 1167642 1169804 + tyrosine protein kinase Wzc%3B catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05350 AFK63_RS05355 AFK63_05370 AFK63_RS05355 1169994 1170839 + glycosyl transferase gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05355 AFK63_RS05360 AFK63_05375 AFK63_RS05360 1170839 1171330 + colanic acid biosynthesis acetyltransferase WcaB acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)%3B wcaB is induced in sessile bacteria and by osmotic shock%2C and repressed when grown in rich medium gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05360 AFK63_RS05365 AFK63_05380 AFK63_RS05365 1171327 1172544 + colanic acid biosynthesis glycosyltransferase WcaC gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05365 AFK63_RS05370 AFK63_05385 wcaD wcaD 1172519 1173739 + colanic acid biosynthesis protein essential for colanic acid biosynthesis%3B colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05370 AFK63_RS05375 AFK63_05390 AFK63_RS05375 1173754 1174506 + colanic acid biosynthesis glycosyltransferase WcaE gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05375 AFK63_RS05380 AFK63_05395 AFK63_RS05380 1174529 1175077 + colanic acid biosynthesis acetyltransferase WcaF gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05380 AFK63_RS05385 AFK63_05400 AFK63_RS05385 1175212 1176333 + GDP-mannose 4%2C6-dehydratase catalyzes the formation of GDP-4-dehydro-6-deoxy-D-mannose from GDP mannose gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05385 AFK63_RS05390 AFK63_05405 AFK63_RS05390 1176336 1177301 + GDP-fucose synthetase bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase%3Bcatalyzes the formation of GDP-fucose from GDP-4-dehydro-6-deoxy-D-mannose gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05390 AFK63_RS05395 AFK63_05410 AFK63_RS05395 1177304 1177783 + GDP-mannose mannosyl hydrolase catalyzes the formation of GDP and D-mannose from GDP-D-mannose%3B also hydrolyzes GDP-glucose gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05395 AFK63_RS05400 AFK63_05415 AFK63_RS05400 1177780 1179003 + glycosyl transferase gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05400 AFK63_RS05405 AFK63_05420 cpsB cpsB 1179007 1180449 + mannose-1-phosphate guanyltransferase capsular polysaccharide colanic acid biosynthesis protein%3B catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05405 AFK63_RS05410 AFK63_05425 AFK63_RS05410 1180570 1181940 + phosphomannomutase capsular polysaccharide biosynthesis protein%3B catalyzes the formation of D-mannose 6-phosphate from alpha-D-mannose 1-phosphate gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05410 AFK63_RS05415 AFK63_05430 AFK63_RS05415 1182055 1183449 + UDP-glucose lipid carrier transferase WcaJ%3B glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05415 AFK63_RS05420 AFK63_05435 AFK63_RS05420 1183462 1184940 + colanic acid exporter gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05420 AFK63_RS05425 AFK63_05440 AFK63_RS05425 1185021 1186301 + colanic acid biosynthesis pyruvyl transferase WcaK gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05425 AFK63_RS05430 AFK63_05445 AFK63_RS05430 1186298 1187518 + colanic acid biosynthesis glycosyltransferase WcaL gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05430 AFK63_RS05435 AFK63_05450 wcaM wcaM 1187530 1188948 + colanic acid biosynthesis protein WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface%3B may be involved in the biosynthesis of colanic acid gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05435 AFK63_RS05440 AFK63_05455 AFK63_RS05440 1189120 1190010 + UTP--glucose-1-phosphate uridylyltransferase gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05440 AFK63_RS05445 AFK63_05460 AFK63_RS05445 1190400 1191482 + dTDP-glucose 4%2C6-dehydratase gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05445 AFK63_RS05450 AFK63_05465 AFK63_RS05450 1191485 1192381 + dTDP-4-dehydrorhamnose reductase with dTDP-4-dehydrorhamnose 3%2C5-epimerase forms a complex known as dTDP-L-rhamnose synthetase%3B catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05450 AFK63_RS05455 AFK63_05470 AFK63_RS05455 1192430 1193308 + glucose-1-phosphate thymidylyltransferase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05455 AFK63_RS05460 AFK63_05475 AFK63_RS05460 1193312 1193860 + dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05460 AFK63_RS05465 AFK63_05480 AFK63_RS05465 1193863 1194282 + dTDP-6-deoxy-3%2C4-keto-hexulose isomerase gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05465 AFK63_RS05470 AFK63_05485 AFK63_RS05470 1194257 1194727 + dTDP-6-deoxy-3%2C4-keto-hexulose isomerase gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05470 AFK63_RS05475 AFK63_05490 AFK63_RS05475 1194720 1195823 + aminotransferase gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05475 AFK63_RS05480 AFK63_05495 AFK63_RS05480 1195820 1197070 + WzxB protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05480 AFK63_RS05485 AFK63_05500 AFK63_RS05485 1197124 1198032 + hypothetical protein gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05485 AFK63_RS05490 AFK63_05505 AFK63_RS05490 1198139 1199221 + glycosyl transferase gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05490 AFK63_RS05495 AFK63_05510 AFK63_RS05495 1200459 1201277 + hypothetical protein gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05495 AFK63_RS05500 AFK63_05515 AFK63_RS05500 1202498 1203904 + 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05500 AFK63_RS05505 AFK63_05520 AFK63_RS05505 1204118 1205110 + chain length determinant protein WzzB regulator of length of O-antigen component of lipopolysaccharide chains gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05505 AFK63_RS05510 AFK63_05525 AFK63_RS05510 1205170 1205781 - phosphoribosyl-ATP pyrophosphatase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05510 AFK63_RS05515 AFK63_05530 AFK63_RS05515 1205775 1206551 - imidazole glycerol phosphate synthase gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05515 AFK63_RS05520 AFK63_05535 AFK63_RS05520 1206533 1207270 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05520 AFK63_RS05525 AFK63_05540 hisH hisH 1207271 1207861 - imidazole glycerol phosphate synthase with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05525 AFK63_RS05530 AFK63_05545 AFK63_RS05530 1207861 1208928 - imidazoleglycerol-phosphate dehydratase catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05530 AFK63_RS05535 AFK63_05550 AFK63_RS05535 1208925 1210007 - histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05535 AFK63_RS05540 AFK63_05555 hisD hisD 1210004 1211308 - histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05540 AFK63_RS05545 AFK63_05560 hisG hisG 1211314 1212213 - ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05545 AFK63_RS05550 AFK63_05565 AFK63_RS05550 1212588 1213412 + hypothetical protein gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05550 AFK63_RS05555 AFK63_05570 AFK63_RS05555 1213396 1214175 - gamma-glutamyl-gamma-aminobutyrate hydrolase gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05555 AFK63_RS05560 AFK63_05575 AFK63_RS05560 1214435 1215730 + 4-aminobutyrate aminotransferase catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05560 AFK63_RS05565 AFK63_05580 AFK63_RS05565 1215921 1217282 + putrescine/spermidine ABC transporter gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05565 AFK63_RS05570 AFK63_05585 sbcB sbcB 1217449 1218924 - exonuclease I Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05570 AFK63_RS05575 AFK63_05590 AFK63_RS05575 1218954 1220105 - acyltransferase gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05575 AFK63_RS05580 AFK63_05595 AFK63_RS05580 1220384 1221514 + D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 5%3B removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05580 AFK63_RS05585 AFK63_05600 AFK63_RS05585 1221601 1222074 + DNA gyrase inhibitor gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05585 AFK63_RS05590 AFK63_05605 AFK63_RS05590 1222277 1223335 + membrane protein gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05590 AFK63_RS05595 AFK63_05610 AFK63_RS05595 1223504 1223842 + hypothetical protein gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05595 AFK63_RS05600 AFK63_05615 AFK63_RS05600 1224856 1225225 + integrase gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05600 AFK63_RS05605 AFK63_05620 AFK63_RS05605 1225754 1225990 - hypothetical protein gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05605 AFK63_RS05610 AFK63_05625 AFK63_RS05610 1226156 1226231 - tRNA-Asn tRNA gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05610 AFK63_RS05615 AFK63_05630 AFK63_RS05615 1226422 1227894 + MATE family multidrug exporter gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05615 AFK63_RS05620 AFK63_05635 AFK63_RS05620 1228044 1228540 + integrase gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05620 AFK63_RS05625 AFK63_05640 AFK63_RS05625 1228943 1229962 + hypothetical protein gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05625 AFK63_RS05630 AFK63_05645 AFK63_RS05630 1230543 1230618 - tRNA-Asn tRNA gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05630 AFK63_RS05635 AFK63_05650 AFK63_RS05635 1230744 1232198 - AMP nucleosidase Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05635 AFK63_RS05640 AFK63_05655 AFK63_RS05640 1232533 1233774 + diguanylate phosphodiesterase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05640 AFK63_RS05645 AFK63_05660 AFK63_RS05645 1234001 1235026 + alkane 1-monooxygenase gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05645 AFK63_RS05650 AFK63_05665 AFK63_RS05650 1235082 1235157 - tRNA-Asn tRNA gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05650 AFK63_RS05655 AFK63_05670 AFK63_RS05655 1235475 1236392 + nitrogen assimilation transcriptional regulator Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05655 AFK63_RS05660 AFK63_05675 cbl cbl 1236494 1237447 + transcriptional regulator Cbl LysR-type transcriptional regulator similar to CysB%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon%3B regulated by CysB%3B DNA-binding transcriptional activator for the ssuEADCB and tauABCD operons gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05660 AFK63_RS05665 AFK63_05680 AFK63_RS05665 1237489 1238808 - shikimate transporter gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05665 AFK63_RS05670 AFK63_05685 AFK63_RS05670 1239072 1239147 - tRNA-Asn tRNA gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05670 AFK63_RS05675 AFK63_05690 AFK63_RS05675 1239249 1240046 - DgsA anti-repressor MtfA Mlc anti-repressor%3B regulates ptsG by binding and inactivating Mlc gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05675 AFK63_RS05680 AFK63_05695 AFK63_RS05680 1240140 1240229 + tRNA-Ser tRNA gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05680 AFK63_RS05685 AFK63_05700 AFK63_RS05685 1240481 1241200 + hypothetical protein gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05685 AFK63_RS05690 AFK63_05705 AFK63_RS05690 1241483 1243024 + cellulose synthase gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05690 AFK63_RS05695 AFK63_05710 AFK63_RS05695 1243036 1243938 - LuxR family transcriptional regulator gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05695 AFK63_RS05700 AFK63_05715 AFK63_RS05700 1244062 1244928 + thiamine biosynthesis protein ThiJ gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05700 AFK63_RS05705 AFK63_05720 AFK63_RS05705 1244938 1245732 + oxidoreductase gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05705 AFK63_RS05710 AFK63_05725 AFK63_RS05710 1245801 1247327 - arylsulfotransferase gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05710 AFK63_RS05715 AFK63_05730 AFK63_RS05715 1247387 1248946 - 5'-nucleotidase gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05715 AFK63_RS05720 AFK63_05735 AFK63_RS05720 1249114 1250367 + hypothetical protein gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05720 AFK63_RS05725 AFK63_05740 AFK63_RS05725 1250413 1250652 - virulence protein MsgA gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05725 AFK63_RS05730 AFK63_05745 AFK63_RS05730 1250802 1251926 - porin allows for ions and hydrophilic solutes to cross the outer membrane gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05730 AFK63_RS05735 AFK63_05750 AFK63_RS05735 1252566 1253264 + hydrolase gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05735 AFK63_RS05740 AFK63_05755 AFK63_RS05740 1253346 1254758 + DNA cytosine methylase gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05740 AFK63_RS05745 AFK63_05760 AFK63_RS05745 1254742 1255239 + very short patch repair endonuclease DNA mismatch endonuclease%3B recognizes and repairs T:G mismatches gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05745 AFK63_RS05750 AFK63_05765 AFK63_RS05750 1255243 1256154 - multidrug DMT transporter gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05750 AFK63_RS05755 AFK63_05770 AFK63_RS05755 1256333 1257247 + hypothetical protein gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05755 AFK63_RS05760 AFK63_05775 AFK63_RS05760 1257337 1257519 + hypothetical protein gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05760 AFK63_RS05765 AFK63_05780 AFK63_RS05765 1257721 1259391 + diguanylate cyclase catalyzes the formation of cyclic di-3'%2C5'-guanylate from guanosine triphosphate%3B involved in the regulation of cellulose biosynthesis gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05765 AFK63_RS05770 AFK63_05785 AFK63_RS05770 1259395 1260210 - mannosyl-3-phosphoglycerate phosphatase gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05770 AFK63_RS05775 AFK63_05790 AFK63_RS05775 1260514 1260726 - hypothetical protein gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05775 AFK63_RS05780 AFK63_05795 AFK63_RS05780 1260850 1261038 + hypothetical protein gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05780 AFK63_RS05785 AFK63_05800 AFK63_RS05785 1261206 1261829 - colanic acid capsular biosynthesis activation protein A gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05785 AFK63_RS05790 AFK63_05805 fliR fliR 1262178 1262966 - flagellar biosynthesis protein FliR FliR%2C with proteins FliP and FliQ%2C forms the core of the central channel in the flagella export apparatus gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05790 AFK63_RS05795 AFK63_05810 fliQ fliQ 1262978 1263247 - flagellar biosynthesis protein FliQ with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05795 AFK63_RS05800 AFK63_05815 fliP fliP 1263259 1263996 - flagellar biosynthesis protein flip FliP%2C with proteins FliQ and FliR%2C forms the core of the central channel in the flagella export apparatus gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05800 AFK63_RS05805 AFK63_05820 AFK63_RS05805 1263996 1264373 - flagellar biosynthesis protein FliO gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05805 AFK63_RS05810 AFK63_05825 fliN fliN 1264374 1264838 - flagellar motor switch protein FliN One of three proteins involved in switching the direction of the flagellar rotation gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05810 AFK63_RS05815 AFK63_05830 fliM fliM 1264831 1265835 - flagellar motor switch protein FliM with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05815 AFK63_RS05820 AFK63_05835 fliL fliL 1265840 1266313 - flagellar basal body-associated protein FliL interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05820 AFK63_RS05825 AFK63_05840 AFK63_RS05825 1266417 1267682 - flagellar hook-length control protein gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05825 AFK63_RS05830 AFK63_05845 fliJ fliJ 1267679 1268122 - flagellar biosynthesis chaperone rod/hook and filament chaperone gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05830 AFK63_RS05835 AFK63_05850 fliI fliI 1268144 1269514 - ATP synthase involved in type III protein export during flagellum assembly gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05835 AFK63_RS05840 AFK63_05855 fliH fliH 1269514 1270218 - flagellar assembly protein H binds to and inhibits the function of flagella specific ATPase FliI gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05840 AFK63_RS05845 AFK63_05860 fliG fliG 1270211 1271233 - flagellar motor switch protein G One of three proteins involved in switching the direction of the flagellar rotation gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05845 AFK63_RS05850 AFK63_05865 AFK63_RS05850 1271230 1272942 - flagellar M-ring protein FliF gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05850 AFK63_RS05855 AFK63_05870 AFK63_RS05855 1273172 1273483 + flagellar hook-basal body protein FliE gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05855 AFK63_RS05860 AFK63_05875 AFK63_RS05860 1273984 1274667 - hypothetical protein gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05860 AFK63_RS05865 AFK63_05880 AFK63_RS05865 1274878 1275420 + type IV secretion protein Rhs gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05865 AFK63_RS05870 AFK63_05885 AFK63_RS05870 1275413 1275835 + hypothetical protein gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05870 AFK63_RS05875 AFK63_05890 AFK63_RS05875 1275952 1276185 - hypothetical protein gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05875 AFK63_RS05880 AFK63_05895 AFK63_RS05880 1276182 1277399 - hypothetical protein gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05880 AFK63_RS05885 AFK63_05900 AFK63_RS05885 1277603 1278016 + lipoprotein gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05885 AFK63_RS05890 AFK63_05905 AFK63_RS05890 1278218 1278580 - flagellar biosynthesis protein FliT gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05890 AFK63_RS05895 AFK63_05910 fliS fliS 1278580 1278990 - flagellar export chaperone FliS flagellin specific chaperone gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05895 AFK63_RS05900 AFK63_05915 AFK63_RS05900 1279000 1280427 - flagellar cap protein FliD gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05900 AFK63_RS05905 AFK63_05920 AFK63_RS05905 1280865 1281701 + flagellin gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05905 AFK63_RS05910 AFK63_05925 AFK63_RS05910 1281975 1283396 + hypothetical protein gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05910 AFK63_RS05915 AFK63_05930 AFK63_RS05915 1283418 1286771 + O-linked N-acetylglucosamine transferase gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05915 AFK63_RS05920 AFK63_05935 AFK63_RS05920 1286841 1287974 + aminotransferase gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05920 AFK63_RS05925 AFK63_05940 AFK63_RS05925 1287971 1288609 + sugar O-acyltransferase gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05925 AFK63_RS05930 AFK63_05945 AFK63_RS05930 1288647 1288886 + hypothetical protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05930 AFK63_RS05935 AFK63_05950 AFK63_RS05935 1288903 1289646 + 3-oxoacyl-ACP reductase gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05935 AFK63_RS05940 AFK63_05955 AFK63_RS05940 1289664 1290407 + 3-oxoacyl-ACP reductase gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05940 AFK63_RS05945 AFK63_05960 AFK63_RS05945 1290404 1291225 + transketolase gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05945 AFK63_RS05950 AFK63_05965 AFK63_RS05950 1291222 1292190 + transketolase gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05950 AFK63_RS05955 AFK63_05970 AFK63_RS05955 1292187 1293602 + AMP-dependent synthetase gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05955 AFK63_RS05960 AFK63_05975 AFK63_RS05960 1293595 1294677 + acyl-protein synthetase gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05960 AFK63_RS05965 AFK63_05980 AFK63_RS05965 1294661 1295863 + acyl-CoA reductase gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05965 AFK63_RS05970 AFK63_05985 fliA fliA 1295996 1296715 + flagellar biosynthesis sigma factor sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor directs late flagellar biosynthesis genes gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05970 AFK63_RS05975 AFK63_05990 AFK63_RS05975 1296776 1297324 + flagella biosynthesis protein FliZ expression activator of the class 2 type of flagellar operons%2C essential to achieve maximal cell motility%3B activator of type 1 fimbrial gene expression%3B cell density-responsive regulator%3B FliZ in Salmonella typhimurium induces HilA%2C an activator of invasion genes necessary to achieve full virulence gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05975 AFK63_RS05980 AFK63_05995 AFK63_RS05980 1297410 1298210 + cystine transporter subunit gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05980 AFK63_RS05985 AFK63_06000 AFK63_RS05985 1298318 1299298 + cysteine desulfhydrase catalyzes the formation of pyruvate from D-cysteine gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05985 AFK63_RS05990 AFK63_06005 AFK63_RS05990 1299320 1299988 + amino acid ABC transporter permease gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05990 AFK63_RS05995 AFK63_06010 AFK63_RS05995 1299985 1300737 + amino acid ABC transporter ATP-binding protein gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS05995 AFK63_RS06000 AFK63_06015 AFK63_RS06000 1300989 1301714 + LuxR family transcriptional regulator gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06000 AFK63_RS06005 AFK63_06020 AFK63_RS06005 1301787 1302011 - hypothetical protein gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06005 AFK63_RS06010 AFK63_06025 sirA sirA 1302494 1303150 + transcriptional regulator in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system%3B in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06010 AFK63_RS06015 AFK63_06030 uvrC uvrC 1303147 1304979 + excinuclease ABC subunit C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06015 AFK63_RS06020 AFK63_06035 AFK63_RS06020 1305036 1305584 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06020 AFK63_RS06025 AFK63_06040 AFK63_RS06025 1305750 1305825 + tRNA-Gly tRNA gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06025 AFK63_RS06030 AFK63_06045 AFK63_RS06030 1305879 1305952 + tRNA-Cys tRNA gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06030 AFK63_RS06035 AFK63_06050 AFK63_RS06035 1305965 1306051 + tRNA-Leu tRNA gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06035 AFK63_RS06040 AFK63_06055 AFK63_RS06040 1306222 1306641 + biotin transporter BioY gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06040 AFK63_RS06045 AFK63_06060 AFK63_RS06045 1306679 1307887 - tyrosine transporter TyrP tyrosine specific permease gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06045 AFK63_RS06050 AFK63_06065 AFK63_RS06050 1308126 1308623 - ferritin cytoplasmic iron storage protein gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06050 AFK63_RS06055 AFK63_06070 AFK63_RS06055 1308905 1309240 - hypothetical protein gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06055 AFK63_RS06060 AFK63_06075 AFK63_RS06060 1309532 1310788 + chemotaxis protein gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06060 AFK63_RS06065 AFK63_06080 AFK63_RS06065 1310926 1311564 + hypothetical protein gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06065 AFK63_RS06070 AFK63_06085 AFK63_RS06070 1311605 1313026 - MFS transporter gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06070 AFK63_RS06075 AFK63_06090 AFK63_RS06075 1313505 1313753 + hypothetical protein gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06075 AFK63_RS06080 AFK63_06095 AFK63_RS06080 1313782 1314384 - lysine transporter LysE gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06080 AFK63_RS06085 AFK63_06100 AFK63_RS06085 1314423 1315265 - AraC family transcriptional regulator gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06085 AFK63_RS06090 AFK63_06105 AFK63_RS06090 1315367 1316710 - C4-dicarboxylate transporter functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to DcuA%3B DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate%2C malate%2C fumarate and succinate) transporters gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06090 AFK63_RS06095 AFK63_06110 AFK63_RS06095 1316918 1317418 - ferritin gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06095 AFK63_RS06100 AFK63_06115 AFK63_RS06100 1317703 1318260 + thiamine biosynthesis protein ThiJ gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06100 AFK63_RS06105 AFK63_06120 AFK63_RS06105 1318315 1318821 + cupin gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06105 AFK63_RS06110 AFK63_06125 AFK63_RS06110 1319111 1320100 + arabinose ABC transporter substrate-binding protein with AraGH is involved in the transport of arabinose into the cell gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06110 AFK63_RS06115 AFK63_06130 araG araG 1320164 1321678 + L-arabinose transporter ATP-binding protein Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06115 AFK63_RS06120 AFK63_06135 araH araH 1321692 1322672 + arabinose ABC transporter permease Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06120 AFK63_RS06125 AFK63_06140 AFK63_RS06125 1322849 1323655 + trehalose phosphatase biosynthetic%3B catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate%3B expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06125 AFK63_RS06130 AFK63_06145 AFK63_RS06130 1323630 1325054 + trehalose-6-phosphate synthase gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06130 AFK63_RS06135 AFK63_06150 AFK63_RS06135 1325100 1325522 - universal stress protein UspC ppGpp-dependent%3B membrane-associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06135 AFK63_RS06140 AFK63_06155 AFK63_RS06140 1326339 1326689 + transcriptional activator FlhD with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06140 AFK63_RS06145 AFK63_06160 AFK63_RS06145 1326693 1327274 + transcriptional regulator With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06145 AFK63_RS06150 AFK63_06165 AFK63_RS06150 1327406 1328293 + flagellar motor protein MotA With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06150 AFK63_RS06155 AFK63_06170 motB motB 1328290 1329219 + flagellar motor protein MotB with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06155 AFK63_RS06160 AFK63_06175 AFK63_RS06160 1329230 1331242 + chemotaxis protein CheA gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06160 AFK63_RS06165 AFK63_06180 AFK63_RS06165 1331271 1331774 + Positive regulator of CheA protein activity (CheW) gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06165 AFK63_RS06170 AFK63_06185 AFK63_RS06170 1332179 1332745 + polyketide synthase gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06170 AFK63_RS06175 AFK63_06190 AFK63_RS06175 1332808 1333320 + fimbrial protein gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06175 AFK63_RS06180 AFK63_06195 AFK63_RS06180 1333340 1334095 + sigma-fimbriae chaperone protein gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06180 AFK63_RS06185 AFK63_06200 AFK63_RS06185 1334074 1336464 + fimbrial assembly protein gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06185 AFK63_RS06190 AFK63_06205 AFK63_RS06190 1336461 1337414 + fimbrial protein gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06190 AFK63_RS06195 AFK63_06210 AFK63_RS06195 1337511 1339178 + chemotaxis protein serine sensor receptor gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06195 AFK63_RS06200 AFK63_06215 AFK63_RS06200 1339215 1339439 + hypothetical protein gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06200 AFK63_RS06205 AFK63_06220 AFK63_RS06205 1339459 1340325 + chemotaxis protein CheR methylates the MCP gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06205 AFK63_RS06210 AFK63_06225 AFK63_RS06210 1340322 1341371 + two-component system protein-glutamate methylesterase response regulator regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06210 AFK63_RS06215 AFK63_06230 AFK63_RS06215 1341389 1341778 + chemotaxis protein CheY chemotaxis regulator that%2C when phosphorylated%2C interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06215 AFK63_RS06220 AFK63_06235 AFK63_RS06220 1341789 1342430 + chemotaxis protein CheZ cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06220 AFK63_RS06225 AFK63_06240 AFK63_RS06225 1342461 1343255 - hypothetical protein gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06225 AFK63_RS06230 AFK63_06245 AFK63_RS06230 1343218 1344780 - deoxyguanosinetriphosphate triphosphohydrolase gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06230 AFK63_RS06235 AFK63_06250 flhB flhB 1345135 1346181 + flagellar biosynthesis protein FlhB membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06235 AFK63_RS06240 AFK63_06255 AFK63_RS06240 1346174 1348252 + flagellar biosynthesis protein FlhA gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06240 AFK63_RS06245 AFK63_06260 AFK63_RS06245 1348252 1348650 + flagellar protein flhE gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06245 AFK63_RS06250 AFK63_06265 AFK63_RS06250 1348932 1350518 + MFS transporter gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06250 AFK63_RS06255 AFK63_06270 AFK63_RS06255 1350518 1351657 + glycosyl hydrolase family 88 gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06255 AFK63_RS06260 AFK63_06275 AFK63_RS06260 1352260 1352886 + hypothetical protein gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06260 AFK63_RS06265 AFK63_06280 AFK63_RS06265 1352944 1354677 - arginyl-tRNA synthetase gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06265 AFK63_RS06270 AFK63_06285 AFK63_RS06270 1354863 1355426 + hypothetical protein gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06270 AFK63_RS06275 AFK63_06290 AFK63_RS06275 1355572 1356114 + cyclase gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06275 AFK63_RS06280 AFK63_06295 AFK63_RS06280 1356118 1357284 + alcohol dehydrogenase gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06280 AFK63_RS06285 AFK63_06300 AFK63_RS06285 1357274 1358425 - aspartate aminotransferase gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06285 AFK63_RS06290 AFK63_06305 AFK63_RS06290 1358511 1359251 + copper homeostasis protein CutC gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06290 AFK63_RS06295 AFK63_06310 AFK63_RS06295 1359261 1359479 - hypothetical protein gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06295 AFK63_RS06300 AFK63_06315 AFK63_RS06300 1359466 1361166 + 2-alkenal reductase gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06300 AFK63_RS06305 AFK63_06320 AFK63_RS06305 1361166 1363007 + hypothetical protein gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06305 AFK63_RS06310 AFK63_06325 AFK63_RS06310 1363176 1363622 + peptidoglycan-binding protein gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06310 AFK63_RS06315 AFK63_06330 AFK63_RS06315 1363664 1364635 - tRNA (mo5U34)-methyltransferase catalyzes the conversion of 5-hydroxyuridine to 5-methoxyuridine in tRNA gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06315 AFK63_RS06320 AFK63_06335 AFK63_RS06320 1364632 1365375 - tRNA (cmo5U34)-methyltransferase catalyzes the conversion of 5-methoxyuridine to uridine-5-oxyacetic acid in tRNA gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06320 AFK63_RS06325 AFK63_06340 AFK63_RS06325 1365416 1365811 - hypothetical protein gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06325 AFK63_RS06330 AFK63_06345 AFK63_RS06330 1365879 1366697 - hypothetical protein gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06330 AFK63_RS06335 AFK63_06350 AFK63_RS06335 1366694 1367260 - hydrolase gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06335 AFK63_RS06340 AFK63_06355 AFK63_RS06340 1367527 1369287 + aspartyl-tRNA synthetase gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06340 AFK63_RS06345 AFK63_06360 nudB nudB 1369517 1369960 + dihydroneopterin triphosphate pyrophosphatase catalyzes the formation of dihydroneopterin phosphate from dihydroneopterin triphosphate gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06345 AFK63_RS06350 AFK63_06365 AFK63_RS06350 1369988 1370728 + transcriptional regulator gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06350 AFK63_RS06355 AFK63_06370 ruvC ruvC 1370763 1371284 + Holliday junction DNA helicase endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06355 AFK63_RS06360 AFK63_06375 ruvA ruvA 1371429 1372040 + ATP-dependent DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06360 AFK63_RS06365 AFK63_06380 AFK63_RS06365 1372049 1373059 + Holliday junction DNA helicase RuvB gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06365 AFK63_RS06370 AFK63_06385 znuB znuB 1373144 1373929 - zinc ABC transporter permease involved in transport of zinc(II) with ZnuA and C gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06370 AFK63_RS06375 AFK63_06390 znuC znuC 1373926 1374681 - zinc ABC transporter ATPase involved in transport of zinc(II) with ZnuA and C gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06375 AFK63_RS06380 AFK63_06395 znuA znuA 1374760 1375704 + zinc ABC transporter substrate-binding protein involved in transport of zinc(II) with ZnuA and C gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06380 AFK63_RS06385 AFK63_06400 AFK63_RS06385 1375783 1377045 + peptidase gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06385 AFK63_RS06390 AFK63_06405 AFK63_RS06390 1377172 1378140 + lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase Transfers myristate or laurate%2C activated on ACP%2C to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06390 AFK63_RS06395 AFK63_06410 AFK63_RS06395 1378377 1379576 + integrase gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06395 AFK63_RS06400 AFK63_06415 AFK63_RS06400 1379573 1380637 + hypothetical protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06400 AFK63_RS06405 AFK63_06420 AFK63_RS06405 1380997 1381506 + DNA repair protein RadC gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06405 AFK63_RS06410 AFK63_06425 AFK63_RS06410 1381572 1383875 - hypothetical protein gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06410 AFK63_RS06415 AFK63_06430 AFK63_RS06415 1384425 1385252 + hypothetical protein gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06415 AFK63_RS06420 AFK63_06435 AFK63_RS06420 1385333 1387408 + chromosome partitioning protein ParB gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06420 AFK63_RS06425 AFK63_06440 AFK63_RS06425 1387470 1387679 + hypothetical protein gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06425 AFK63_RS06430 AFK63_06445 AFK63_RS06430 1388455 1388769 + hypothetical protein gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06430 AFK63_RS06435 AFK63_06450 AFK63_RS06435 1389082 1389318 - TRANSCRIPTION REGULATOR PROTEIN gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06435 AFK63_RS06440 AFK63_06455 AFK63_RS06440 1389693 1390010 + lipoprotein gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06440 AFK63_RS06445 AFK63_06460 AFK63_RS06445 1390353 1391123 + hypothetical protein gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06445 AFK63_RS06450 AFK63_06465 AFK63_RS06450 1391237 1391554 + transcriptional regulator gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06450 AFK63_RS06455 AFK63_06470 AFK63_RS06455 1391581 1392426 + Plasmid replication initiator protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06455 AFK63_RS06460 AFK63_06475 AFK63_RS06460 1392668 1393306 + ATPase gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06460 AFK63_RS06465 AFK63_06480 AFK63_RS06465 1393303 1393566 + chromosome partitioning protein ParB gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06465 AFK63_RS06470 AFK63_06485 AFK63_RS06470 1393563 1394120 + transposase gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06470 AFK63_RS06475 AFK63_06490 AFK63_RS06475 1394117 1394704 + peptidase gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06475 AFK63_RS06480 AFK63_06495 AFK63_RS06480 1394701 1395156 + hypothetical protein gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06480 AFK63_RS06485 AFK63_06500 AFK63_RS06485 1395153 1397132 + type VI secretion protein gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06485 AFK63_RS06490 AFK63_06505 AFK63_RS06490 1397196 1397780 - TetR family transcriptional regulator gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06490 AFK63_RS06495 AFK63_06510 AFK63_RS06495 1397859 1398731 + alpha/beta hydrolase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06495 AFK63_RS06500 AFK63_06515 AFK63_RS06500 1398933 1399235 - 4Fe-4S ferredoxin gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06500 AFK63_RS06505 AFK63_06520 AFK63_RS06505 1399378 1399968 + TetR family transcriptional regulator gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06505 AFK63_RS06510 AFK63_06525 AFK63_RS06510 1400099 1402024 - hypothetical protein gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06510 AFK63_RS06515 AFK63_06530 AFK63_RS06515 1402286 1402876 + TetR family transcriptional regulator gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06515 AFK63_RS06520 AFK63_06535 AFK63_RS06520 1403086 1404609 + OprM gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06520 AFK63_RS06525 AFK63_06540 AFK63_RS06525 1404654 1405739 + hemolysin D gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06525 AFK63_RS06530 AFK63_06545 AFK63_RS06530 1405736 1408825 + ACR family transporter gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06530 AFK63_RS06535 AFK63_06550 AFK63_RS06535 1409227 1409919 + membrane protein gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06535 AFK63_RS06540 AFK63_06555 AFK63_RS06540 1410085 1411044 + outer membrane protein romA gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06540 AFK63_RS06545 AFK63_06560 AFK63_RS06545 1411244 1412266 + hypothetical protein gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06545 AFK63_RS06550 AFK63_06565 AFK63_RS06550 1412346 1413260 + dehydrogenase gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06550 AFK63_RS06555 AFK63_06570 AFK63_RS06555 1413391 1414335 + hypothetical protein gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06555 AFK63_RS06560 AFK63_06575 AFK63_RS06560 1414443 1415372 - alcohol dehydrogenase gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06560 AFK63_RS06565 AFK63_06580 AFK63_RS06565 1415382 1416710 - lysophospholipase gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06565 AFK63_RS06570 AFK63_06585 AFK63_RS06570 1416694 1417563 - oxidoreductase gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06570 AFK63_RS06575 AFK63_06590 AFK63_RS06575 1417619 1418743 - alpha/beta hydrolase gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06575 AFK63_RS06580 AFK63_06595 AFK63_RS06580 1418995 1419690 - TetR family transcriptional regulator gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06580 AFK63_RS06585 AFK63_06600 AFK63_RS06585 1419806 1420750 + LysR family transcriptional regulator gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06585 AFK63_RS06590 AFK63_06605 AFK63_RS06590 1420747 1421010 + lipoprotein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06590 AFK63_RS06595 AFK63_06610 AFK63_RS06595 1421244 1423241 + conjugal transfer protein TraG gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06595 AFK63_RS06600 AFK63_06615 AFK63_RS06600 1423238 1423714 + CopG family transcriptional regulator gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06600 AFK63_RS06605 AFK63_06620 AFK63_RS06605 1423711 1424790 + conjugal transfer protein TrbB gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06605 AFK63_RS06610 AFK63_06625 AFK63_RS06610 1424777 1425163 + hypothetical protein gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06610 AFK63_RS06615 AFK63_06630 AFK63_RS06615 1425160 1425429 + type IV secretion system protein VirB3 gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06615 AFK63_RS06620 AFK63_06635 AFK63_RS06620 1425442 1427892 + conjugal transfer protein TrbE gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06620 AFK63_RS06625 AFK63_06640 AFK63_RS06625 1427889 1428632 + hypothetical protein gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06625 AFK63_RS06630 AFK63_06645 AFK63_RS06630 1428645 1428971 + lipoprotein gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06630 AFK63_RS06635 AFK63_06650 AFK63_RS06635 1428968 1430335 + conjugal transfer protein TrbL gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06635 AFK63_RS06640 AFK63_06655 AFK63_RS06640 1430354 1431058 + hypothetical protein gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06640 AFK63_RS06645 AFK63_06660 AFK63_RS06645 1431055 1432047 + conjugal transfer protein TrbG gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06645 AFK63_RS06650 AFK63_06665 AFK63_RS06650 1432050 1433333 + conjugal transfer protein TrbI gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06650 AFK63_RS06655 AFK63_06670 AFK63_RS06655 1433330 1433575 + hypothetical protein gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06655 AFK63_RS06660 AFK63_06675 AFK63_RS06660 1433876 1435318 - pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06660 AFK63_RS06665 AFK63_06680 AFK63_RS06665 1435447 1436313 - transcriptional regulator Represses the expression of the zwf%2C eda%2C glp and gap gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06665 AFK63_RS06670 AFK63_06685 AFK63_RS06670 1436668 1438143 + glucose-6-phosphate dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06670 AFK63_RS06675 AFK63_06690 AFK63_RS06675 1438374 1440185 + phosphogluconate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06675 AFK63_RS06680 AFK63_06695 AFK63_RS06680 1440243 1440881 + keto-deoxy-phosphogluconate aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06680 AFK63_RS06685 AFK63_06700 AFK63_RS06685 1440933 1442111 - phosphoribosylglycinamide formyltransferase gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06685 AFK63_RS06690 AFK63_06705 AFK63_RS06690 1442245 1442595 + LexA family transcriptional regulator gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06690 AFK63_RS06695 AFK63_06710 AFK63_RS06695 1442739 1442978 - hypothetical protein gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06695 AFK63_RS06700 AFK63_06715 AFK63_RS06700 1442980 1443327 + hypothetical protein secreted protein%3B unknown function gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06700 AFK63_RS06705 AFK63_06720 AFK63_RS06705 1443443 1444126 + membrane protein gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06705 AFK63_RS06710 AFK63_06725 AFK63_RS06710 1444216 1446279 + protease 2 PtrB%3B oligopeptidase that cleaves peptide bonds following arginine and lysine residues gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06710 AFK63_RS06715 AFK63_06730 AFK63_RS06715 1446276 1446938 - exodeoxyribonuclease X 3'-5' exonuclease activity on single or double-strand DNA gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06715 AFK63_RS06720 AFK63_06735 AFK63_RS06720 1447015 1447245 - DNA polymerase III theta subunit gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06720 AFK63_RS06725 AFK63_06740 AFK63_RS06725 1447392 1447766 + hypothetical protein gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06725 AFK63_RS06730 AFK63_06745 AFK63_RS06730 1447771 1448640 + membrane protein gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06730 AFK63_RS06735 AFK63_06750 AFK63_RS06735 1448655 1448993 + hypothetical protein gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06735 AFK63_RS06740 AFK63_06755 AFK63_RS06740 1449970 1450614 + serine/threonine protein phosphatase gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06740 AFK63_RS06745 AFK63_06760 AFK63_RS06745 1450615 1450806 - hypothetical protein gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06745 AFK63_RS06750 AFK63_06765 AFK63_RS06750 1450917 1451156 - hypothetical protein gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06750 AFK63_RS06755 AFK63_06770 yebU yebU 1451267 1452709 - RNA methyltransferase RsmF in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06755 AFK63_RS06760 AFK63_06775 AFK63_RS06760 1452786 1455419 - hypothetical protein gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06760 AFK63_RS06765 AFK63_06780 AFK63_RS06765 1455388 1456671 - membrane protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06765 AFK63_RS06770 AFK63_06785 AFK63_RS06770 1456800 1457294 + methionine-R-sulfoxide reductase gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06770 AFK63_RS06775 AFK63_06790 AFK63_RS06775 1457395 1458084 + prop expression regulator affects solute and DNA transport through an unknown mechanism gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06775 AFK63_RS06780 AFK63_06795 AFK63_RS06780 1458104 1460152 + carboxyl-terminal processing protease Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06780 AFK63_RS06785 AFK63_06800 AFK63_RS06785 1460348 1461229 + protease HtpX metalloprotease gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06785 AFK63_RS06790 AFK63_06805 AFK63_RS06790 1461490 1462281 + transcriptional regulator KdgR%2C KDG operon repressor regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06790 AFK63_RS06795 AFK63_06810 AFK63_RS06795 1462340 1462579 - membrane protein gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06795 AFK63_RS06800 AFK63_06815 AFK63_RS06800 1462738 1462881 + PhoP family transcriptional regulator gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06800 AFK63_RS06805 AFK63_06820 AFK63_RS06805 1462948 1463229 + hypothetical protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06805 AFK63_RS06810 AFK63_06825 AFK63_RS06810 1463250 1464257 + MBL fold metallo-hydrolase gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06810 AFK63_RS06815 AFK63_06830 AFK63_RS06815 1464935 1465144 + cold-shock protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06815 AFK63_RS06820 AFK63_06835 rrmA rrmA 1465298 1466113 + 23S rRNA methyltransferase methylates the guanosine in position 745 of 23S rRNA%3B required for translation and cell growth gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06820 AFK63_RS06825 AFK63_06840 AFK63_RS06825 1466110 1466676 - hypothetical protein membrane protein YebN gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06825 AFK63_RS06830 AFK63_06845 AFK63_RS06830 1467052 1467510 - hypothetical protein gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06830 AFK63_RS06835 AFK63_06850 AFK63_RS06835 1467571 1468422 - PTS mannose transporter subunit IID hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06835 AFK63_RS06840 AFK63_06855 AFK63_RS06840 1468435 1469235 - PTS mannose transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06840 AFK63_RS06845 AFK63_06860 AFK63_RS06845 1469301 1470263 - PTS mannose transporter subunit IIAB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06845 AFK63_RS06850 AFK63_06865 AFK63_RS06850 1470726 1472285 + membrane protein gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06850 AFK63_RS06855 AFK63_06870 AFK63_RS06855 1472289 1473887 - c-di-GMP phosphodiesterase gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06855 AFK63_RS06860 AFK63_06875 AFK63_RS06860 1474020 1475384 - serine dehydratase catalyzes the formation of pyruvate from serine gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06860 AFK63_RS06865 AFK63_06880 AFK63_RS06865 1475556 1476134 - NUDIX hydrolase gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06865 AFK63_RS06870 AFK63_06885 pabB pabB 1476137 1477501 - aminodeoxychorismate synthase para-aminobenzoate synthase component 1%3B catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and L-glutamine gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06870 AFK63_RS06875 AFK63_06890 AFK63_RS06875 1477594 1477776 + hypothetical protein gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06875 AFK63_RS06880 AFK63_06895 AFK63_RS06880 1477918 1478925 + 3-oxoacyl-ACP synthase gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06880 AFK63_RS06885 AFK63_06900 AFK63_RS06885 1478922 1479926 + hypothetical protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06885 AFK63_RS06890 AFK63_06905 AFK63_RS06890 1479927 1480733 + MBL fold hydrolase gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06890 AFK63_RS06895 AFK63_06910 AFK63_RS06895 1480730 1482016 + coenzyme F390 synthetase gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06895 AFK63_RS06900 AFK63_06915 AFK63_RS06900 1482013 1482630 + acid phosphatase gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06900 AFK63_RS06905 AFK63_06920 AFK63_RS06905 1482623 1483741 + fatty acid hydroxylase gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06905 AFK63_RS06910 AFK63_06925 AFK63_RS06910 1483734 1484825 + linoleoyl-CoA desaturase gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06910 AFK63_RS06915 AFK63_06930 AFK63_RS06915 1484815 1485915 + linoleoyl-CoA desaturase gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06915 AFK63_RS06920 AFK63_06935 AFK63_RS06920 1485933 1486277 - endoribonuclease L-PSP gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06920 AFK63_RS06925 AFK63_06940 AFK63_RS06925 1486407 1488317 + ATP-dependent helicase gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06925 AFK63_RS06930 AFK63_06945 AFK63_RS06930 1488387 1489082 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06930 AFK63_RS06935 AFK63_06950 AFK63_RS06935 1489123 1489707 + membrane protein gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06935 AFK63_RS06940 AFK63_06955 AFK63_RS06940 1489913 1491598 + long-chain fatty acid--CoA ligase Activates fatty acids by binding to coenzyme A gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06940 AFK63_RS06945 AFK63_06960 AFK63_RS06945 1491681 1492793 + ribonuclease D gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06945 AFK63_RS06950 AFK63_06965 minE minE 1492895 1493161 - cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06950 AFK63_RS06955 AFK63_06970 AFK63_RS06955 1493165 1493977 - cell division inhibitor MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06955 AFK63_RS06960 AFK63_06975 minC minC 1494002 1494697 - septum formation inhibitor blocks the formation of polar Z-ring septums gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06960 AFK63_RS06965 AFK63_06980 AFK63_RS06965 1494823 1495098 + hypothetical protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06965 AFK63_RS06970 AFK63_06985 AFK63_RS06970 1495236 1495895 + hypothetical protein gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06970 AFK63_RS06975 AFK63_06990 AFK63_RS06975 1495984 1496430 + hypothetical protein gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06975 AFK63_RS06980 AFK63_06995 AFK63_RS06980 1496875 1497102 - hypothetical protein gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06980 AFK63_RS06985 AFK63_07000 AFK63_RS06985 1497566 1498099 - disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06985 AFK63_RS06990 AFK63_07005 nhaB nhaB 1498235 1499797 - sodium/proton antiporter involved in regulation of intracellular pH under alkaline conditions gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06990 AFK63_RS06995 AFK63_07010 AFK63_RS06995 1500009 1500728 + fatty acid metabolism regulator Multifunctional regulator of fatty acid metabolism gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS06995 AFK63_RS07000 AFK63_07015 AFK63_RS07000 1500790 1502325 - SpoVR family protein gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07000 AFK63_RS07005 AFK63_07020 AFK63_RS07005 1502649 1503947 + amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07005 AFK63_RS07010 AFK63_07025 AFK63_RS07010 1503960 1505030 + alanine racemase converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07010 AFK63_RS07015 AFK63_07030 cvrA cvrA 1505106 1506836 - potassium/proton antiporter the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter%3B can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07015 AFK63_RS07020 AFK63_07035 AFK63_RS07020 1507096 1508001 - LysR family transcriptional regulator gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07020 AFK63_RS07025 AFK63_07040 AFK63_RS07025 1508181 1509239 + aldo/keto reductase gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07025 AFK63_RS07030 AFK63_07045 AFK63_RS07030 1509308 1509601 + hypothetical protein gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07030 AFK63_RS07035 AFK63_07050 AFK63_RS07035 1509740 1510321 - NADPH:quinone oxidoreductase gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07035 AFK63_RS07040 AFK63_07055 AFK63_RS07040 1510393 1511583 - membrane protein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07040 AFK63_RS07045 AFK63_07060 AFK63_RS07045 1511672 1512466 + AraC family transcriptional regulator gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07045 AFK63_RS07050 AFK63_07065 AFK63_RS07050 1512718 1513113 + membrane protein gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07050 AFK63_RS07055 AFK63_07070 AFK63_RS07055 1513110 1513742 + TetR family transcriptional regulator gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07055 AFK63_RS07060 AFK63_07075 AFK63_RS07060 1513915 1514100 - hypothetical protein gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07060 AFK63_RS07065 AFK63_07080 AFK63_RS07065 1514157 1515092 - peptidase S66 gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07065 AFK63_RS07070 AFK63_07085 AFK63_RS07070 1515222 1515833 + murein transglycosylase gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07070 AFK63_RS07075 AFK63_07090 AFK63_RS07075 1515834 1516565 - flagellar brake protein gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07075 AFK63_RS07080 AFK63_07095 AFK63_RS07080 1516782 1517036 + hypothetical protein gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07080 AFK63_RS07085 AFK63_07100 AFK63_RS07085 1517092 1519206 - ferrioxamine B receptor gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07085 AFK63_RS07090 AFK63_07105 treA treA 1519412 1521343 - trehalase periplasmic%3B catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07090 AFK63_RS07095 AFK63_07110 AFK63_RS07095 1521477 1522493 - LacI family transcriptional regulator gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07095 AFK63_RS07100 AFK63_07115 AFK63_RS07100 1522490 1523239 - ribonuclease Z gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07100 AFK63_RS07105 AFK63_07120 AFK63_RS07105 1523395 1524372 + putrescine/spermidine ABC transporter ATPase gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07105 AFK63_RS07110 AFK63_07125 AFK63_RS07110 1524405 1525550 + ABC transporter substrate-binding protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07110 AFK63_RS07115 AFK63_07130 AFK63_RS07115 1525611 1526444 + ABC transporter permease gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07115 AFK63_RS07120 AFK63_07135 AFK63_RS07120 1526492 1527301 + spermidine/putrescine ABC transporter permease gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07120 AFK63_RS07125 AFK63_07140 AFK63_RS07125 1527308 1528705 - GntR family transcriptional regulator gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07125 AFK63_RS07130 AFK63_07145 AFK63_RS07130 1528827 1529306 + alkylhydroperoxidase gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07130 AFK63_RS07135 AFK63_07150 AFK63_RS07135 1529564 1530271 + Uncharacterized phage-encoded protein gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07135 AFK63_RS07140 AFK63_07155 AFK63_RS07140 1530464 1532122 + hypothetical protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07140 AFK63_RS07145 AFK63_07160 AFK63_RS07145 1532129 1532725 - NAD(P)H dehydrogenase gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07145 AFK63_RS07150 AFK63_07165 AFK63_RS07150 1532839 1533426 + TetR family transcriptional regulator gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07150 AFK63_RS07155 AFK63_07170 AFK63_RS07155 1533586 1534371 + hypothetical protein gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07155 AFK63_RS07160 AFK63_07175 AFK63_RS07160 1534568 1535236 - hypothetical protein gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07160 AFK63_RS07165 AFK63_07180 ychF ychF 1535464 1536555 - GTP-binding protein EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07165 AFK63_RS07170 AFK63_07185 AFK63_RS07170 1536695 1537279 - peptidyl-tRNA hydrolase gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07170 AFK63_RS07175 AFK63_07190 AFK63_RS07175 1537547 1537819 + hypothetical protein YchH%3B transcription activated by CRP (cyclic AMP receptor protein)%2C a global transcription factor involved in regulation of metabolism in enteric bacteria%3B ychH presents a class II promoter to bind CRP%3B unknown function gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07175 AFK63_RS07180 AFK63_07195 AFK63_RS07180 1537937 1538983 + MerR family transcriptional regulator gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07180 AFK63_RS07185 AFK63_07200 AFK63_RS07185 1538990 1540669 - transporter role in sulfate transport across the inner membrane%3B member of the SulP family of sulfate transporters%3B seems to mediate transport via sulfate/proton symport gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07185 AFK63_RS07190 AFK63_07205 AFK63_RS07190 1540789 1541754 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07190 AFK63_RS07195 AFK63_07210 AFK63_RS07195 1541864 1542733 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07195 AFK63_RS07200 AFK63_07215 lolB lolB 1542730 1543353 - outer membrane lipoprotein LolB Incorporates lipoproteins in the outer membrane after they are released by the LolA protein gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07200 AFK63_RS07205 AFK63_07220 hemA hemA 1543553 1544809 + glutamyl-tRNA reductase catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH%3B the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid%3B functions in porphyrin (tetrapyrroles) biosynthesis%3B the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07205 AFK63_RS07210 AFK63_07225 prfA prfA 1544847 1545929 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07210 AFK63_RS07215 AFK63_07230 AFK63_RS07215 1545929 1546771 + SAM-dependent methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07215 AFK63_RS07220 AFK63_07235 AFK63_RS07220 1546778 1547173 + protein sirB2 gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07220 AFK63_RS07225 AFK63_07240 AFK63_RS07225 1547170 1547979 + hypothetical protein gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07225 AFK63_RS07230 AFK63_07245 AFK63_RS07230 1548022 1548876 + 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07230 AFK63_RS07235 AFK63_07250 AFK63_RS07235 1548994 1550097 - calcium/sodium:proton antiporter gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07235 AFK63_RS07240 AFK63_07255 chaB chaB 1550372 1550602 + cation transport regulator in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA%3B has weak affinity for calcium and magnesium ions gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07240 AFK63_RS07245 AFK63_07260 AFK63_RS07245 1550819 1551517 + transporter gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07245 AFK63_RS07250 AFK63_07265 AFK63_RS07250 1551566 1551811 - hypothetical protein gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07250 AFK63_RS07255 AFK63_07270 AFK63_RS07255 1552022 1553809 - chemotaxis protein gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07255 AFK63_RS07260 AFK63_07275 AFK63_RS07260 1553959 1554312 - hypothetical protein gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07260 AFK63_RS07265 AFK63_07280 AFK63_RS07265 1554384 1555589 + nitrate regulatory protein gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07265 AFK63_RS07270 AFK63_07285 AFK63_RS07270 1556294 1557544 + nitrate ABC transporter substrate-binding protein gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07270 AFK63_RS07275 AFK63_07290 AFK63_RS07275 1557554 1558435 + nitrate ABC transporter permease gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07275 AFK63_RS07280 AFK63_07295 AFK63_RS07280 1558445 1559233 + nitrate ABC transporter ATP-binding protein gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07280 AFK63_RS07285 AFK63_07300 AFK63_RS07285 1560437 1563310 + nitrite reductase gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07285 AFK63_RS07290 AFK63_07305 AFK63_RS07290 1563307 1565997 + nitrate reductase gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07290 AFK63_RS07295 AFK63_07310 AFK63_RS07295 1565905 1566456 - phosphatidylethanolamine-binding protein gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07295 AFK63_RS07300 AFK63_07315 AFK63_RS07300 1566584 1568050 + invasin gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07300 AFK63_RS07305 AFK63_07320 AFK63_RS07305 1568047 1568697 - transcriptional regulator two-component response regulator NarL%3B phosphorylated by NarQ%3B activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07305 AFK63_RS07310 AFK63_07325 AFK63_RS07310 1568690 1570498 - nitrate/nitrite two-component system sensor histidine kinase gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07310 AFK63_RS07315 AFK63_07330 AFK63_RS07315 1570796 1572202 + nitrate/nitrite transporter NarK involved in the transport of nitrate and nitrite gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07315 AFK63_RS07320 AFK63_07335 narZ narZ 1572630 1576376 + nitrate reductase with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07320 AFK63_RS07325 AFK63_07340 narH narH 1576373 1577908 + nitrate reductase with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07325 AFK63_RS07330 AFK63_07345 AFK63_RS07330 1577905 1578615 + nitrate reductase delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07330 AFK63_RS07335 AFK63_07350 narI narI 1578615 1579292 + nitrate reductase with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07335 AFK63_RS07340 AFK63_07355 AFK63_RS07340 1579721 1579900 + hypothetical protein gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07340 AFK63_RS07345 AFK63_07360 AFK63_RS07345 1579929 1580873 - AraC family transcriptional regulator gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07345 AFK63_RS07350 AFK63_07365 AFK63_RS07350 1580968 1581738 + dehydrogenase gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07350 AFK63_RS07355 AFK63_07370 AFK63_RS07355 1581807 1582604 - XRE family transcriptional regulator gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07355 AFK63_RS07360 AFK63_07375 AFK63_RS07360 1582708 1584156 + MFS transporter gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07360 AFK63_RS07365 AFK63_07380 AFK63_RS07365 1584443 1584527 - tRNA-Tyr tRNA gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07365 AFK63_RS07370 AFK63_07385 AFK63_RS07370 1584557 1584641 - tRNA-Tyr tRNA gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07370 AFK63_RS07375 AFK63_07390 AFK63_RS07375 1584797 1585639 - formyltetrahydrofolate deformylase gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07375 AFK63_RS07380 AFK63_07395 AFK63_RS07380 1585691 1586050 - SEC-C protein gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07380 AFK63_RS07385 AFK63_07400 AFK63_RS07385 1586551 1587564 + transcriptional regulator gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07385 AFK63_RS07390 AFK63_07405 AFK63_RS07390 1587766 1588674 + UTP--glucose-1-phosphate uridylyltransferase together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase%2C an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate%3B regulates cellular levels of UDP-glucose gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07390 AFK63_RS07395 AFK63_07410 AFK63_RS07395 1588697 1590037 + UDP-glucose 6-dehydrogenase gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07395 AFK63_RS07400 AFK63_07415 AFK63_RS07400 1590052 1591065 + protein CapI gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07400 AFK63_RS07405 AFK63_07420 AFK63_RS07405 1591174 1591587 - DNA-binding protein gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07405 AFK63_RS07410 AFK63_07425 AFK63_RS07410 1592129 1592734 + thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07410 AFK63_RS07415 AFK63_07430 AFK63_RS07415 1593044 1595725 - acetaldehyde dehydrogenase gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07415 AFK63_RS07420 AFK63_07435 AFK63_RS07420 1596207 1596845 + hypothetical protein gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07420 AFK63_RS07425 AFK63_07440 AFK63_RS07425 1597637 1599265 + peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07425 AFK63_RS07430 AFK63_07445 oppB oppB 1599349 1600269 + oligopeptide transporter permease gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07430 AFK63_RS07435 AFK63_07450 AFK63_RS07435 1600284 1601192 + peptide ABC transporter permease with OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07435 AFK63_RS07440 AFK63_07455 oppD oppD 1601204 1602217 + peptide ABC transporter ATP-binding protein gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07440 AFK63_RS07445 AFK63_07460 AFK63_RS07445 1602214 1603218 + peptide ABC transporter ATP-binding protein with OppABCD is involved in the transport of oligopeptides%3B OppF and OppD are ATP-binding proteins gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07445 AFK63_RS07450 AFK63_07465 AFK63_RS07450 1603264 1604100 + transporter gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07450 AFK63_RS07455 AFK63_07470 AFK63_RS07455 1604127 1604450 - dsDNA-mimic protein highly acidic protein%3B the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi)%3B binds heat-unstable protein (HU-alpha) which is a histone-like protein gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07455 AFK63_RS07460 AFK63_07475 cls cls 1604491 1605951 - cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07460 AFK63_RS07465 AFK63_07480 AFK63_RS07465 1606765 1607034 + hypothetical protein gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07465 AFK63_RS07470 AFK63_07485 AFK63_RS07470 1607119 1607415 - hypothetical protein unknown function%3B YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase%2C but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07470 AFK63_RS07475 AFK63_07490 AFK63_RS07475 1607638 1608372 + energy transducer TonB membrane spanning protein in TonB-ExbB-ExbD complex%3B transduces proton motive force of the cytoplasmic membrane to outer membrane transporters%3B involved in the transport of ron-siderophore complexes%2C vitamin B12 and colicins gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07475 AFK63_RS07480 AFK63_07495 AFK63_RS07480 1608592 1608993 - acyl-CoA esterase gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07480 AFK63_RS07485 AFK63_07500 AFK63_RS07485 1609167 1611356 - outer membrane receptor protein Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07485 AFK63_RS07490 AFK63_07505 AFK63_RS07490 1611597 1612133 - intracellular septation protein A Involved in cell division%3B probably involved in intracellular septation gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07490 AFK63_RS07495 AFK63_07510 AFK63_RS07495 1612187 1612930 - hypothetical protein gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07495 AFK63_RS07500 AFK63_07515 AFK63_RS07500 1612955 1613362 - ferredoxin gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07500 AFK63_RS07505 AFK63_07520 AFK63_RS07505 1613645 1614277 + membrane protein receptor for colicin S4 gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07505 AFK63_RS07510 AFK63_07525 AFK63_RS07510 1614417 1614698 - hypothetical protein gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07510 AFK63_RS07515 AFK63_07530 AFK63_RS07515 1614948 1615757 - tryptophan synthase subunit alpha gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07515 AFK63_RS07520 AFK63_07535 AFK63_RS07520 1615757 1616950 - tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07520 AFK63_RS07525 AFK63_07540 AFK63_RS07525 1616963 1618321 - indole-3-glycerol phosphate synthase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07525 AFK63_RS07530 AFK63_07545 AFK63_RS07530 1618325 1619920 - glutamine amidotransferase bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase%3B TrpD%3B forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine%3B also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate%3B functions in tryptophan biosynthesis gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07530 AFK63_RS07535 AFK63_07550 AFK63_RS07535 1619920 1621482 - anthranilate synthase component I with component II%2C the glutamine amidotransferase%2C catalyzes the formation of anthranilate from chorismate and glutamine gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07535 AFK63_RS07540 AFK63_07555 AFK63_RS07540 1621760 1622638 + S-adenosylmethionine tRNA ribosyltransferase gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07540 AFK63_RS07545 AFK63_07560 AFK63_RS07545 1622635 1623255 + hypothetical protein gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07545 AFK63_RS07550 AFK63_07565 AFK63_RS07550 1623384 1624520 + ribosomal large subunit pseudouridine synthase B gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07550 AFK63_RS07555 AFK63_07570 AFK63_RS07555 1624575 1625165 - cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase catalyzes the formation of adenosylcobalamide from cobinamide and the formation of coenzyme B12 from cob(I)alamin gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07555 AFK63_RS07560 AFK63_07575 AFK63_RS07560 1625162 1625923 - 3-oxoacyl-ACP reductase gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07560 AFK63_RS07565 AFK63_07580 AFK63_RS07565 1626184 1627233 + peptidase multicopy suppressor of htrA(degP) gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07565 AFK63_RS07570 AFK63_07585 AFK63_RS07570 1627312 1627563 - hypothetical protein gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07570 AFK63_RS07575 AFK63_07590 AFK63_RS07575 1627965 1630562 + DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07575 AFK63_RS07580 AFK63_07595 cysB cysB 1630751 1631725 + CysB family transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07580 AFK63_RS07585 AFK63_07600 AFK63_RS07585 1632803 1635478 + aconitate hydratase Catalyzes the conversion of citrate to isocitrate gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07585 AFK63_RS07590 AFK63_07605 ribA ribA 1635534 1636127 - GTP cyclohydrolase catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07590 AFK63_RS07595 AFK63_07610 AFK63_RS07595 1636326 1637090 + phosphatidylglycerophosphatase gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07595 AFK63_RS07600 AFK63_07615 AFK63_RS07600 1637238 1637546 + membrane protein gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07600 AFK63_RS07605 AFK63_07620 AFK63_RS07605 1637553 1638722 + tetratricopeptide repeat protein gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07605 AFK63_RS07610 AFK63_07625 AFK63_RS07610 1638900 1639691 + orotidine 5'-phosphate decarboxylase gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07610 AFK63_RS07615 AFK63_07630 AFK63_RS07615 1639691 1640017 + translation initiation factor Sui1 involved in start site selection during the initiation of translation gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07615 AFK63_RS07620 AFK63_07635 AFK63_RS07620 1640139 1640354 - lipoprotein gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07620 AFK63_RS07625 AFK63_07640 AFK63_RS07625 1640641 1641396 - DeoR family transcriptional regulator gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07625 AFK63_RS07630 AFK63_07645 AFK63_RS07630 1641442 1643874 - formate acetyltransferase gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07630 AFK63_RS07635 AFK63_07650 AFK63_RS07635 1643880 1644779 - pyruvate formate lyase-activating protein gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07635 AFK63_RS07640 AFK63_07655 AFK63_RS07640 1644916 1645578 + fructose-6-phosphate aldolase similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07640 AFK63_RS07645 AFK63_07660 AFK63_RS07645 1645594 1645776 - hypothetical protein gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07645 AFK63_RS07650 AFK63_07665 AFK63_RS07650 1645989 1646858 + enoyl-CoA hydratase regulator of pathogenicity factor RpfF%3B involved in synthesis of a diffusible signal factor involved in the regulation of extracellular enzymes gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07650 AFK63_RS07655 AFK63_07670 AFK63_RS07655 1646881 1648875 - RNase II stability modulator c-di-GMP phosphodiesterase%3B probably degrades signalling molecule c-di-GMP gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07655 AFK63_RS07660 AFK63_07675 AFK63_RS07660 1649185 1651119 - exoribonuclease II Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07660 AFK63_RS07665 AFK63_07680 AFK63_RS07665 1651208 1652362 - hypothetical protein gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07665 AFK63_RS07670 AFK63_07685 AFK63_RS07670 1652552 1653340 - enoyl-ACP reductase Catalyzes a key regulatory step in fatty acid biosynthesis gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07670 AFK63_RS07675 AFK63_07690 AFK63_RS07675 1653461 1654267 - peptide ABC transporter ATP-binding protein gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07675 AFK63_RS07680 AFK63_07695 AFK63_RS07680 1654269 1655261 - peptide ABC transporter ATP-binding protein involved in resistance to antimibial peptides gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07680 AFK63_RS07685 AFK63_07700 AFK63_RS07685 1655261 1656151 - peptide ABC transporter permease gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07685 AFK63_RS07690 AFK63_07705 AFK63_RS07690 1656138 1657103 - peptide ABC transporter permease gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07690 AFK63_RS07695 AFK63_07710 AFK63_RS07695 1657100 1658740 - peptide ABC transporter substrate-binding protein gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07695 AFK63_RS07700 AFK63_07715 pspF pspF 1658838 1659824 - phage shock protein transcriptional activator for pspABCE which are induced in response to phage proteins%2C membrane altering stresses%2C and impaired proton expor gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07700 AFK63_RS07705 AFK63_07720 AFK63_RS07705 1659993 1660664 + phage shock protein involved in maintaining membrane potential under membrane stress conditions%3B also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07705 AFK63_RS07710 AFK63_07725 pspB pspB 1660730 1660954 + phage-shock protein DNA-binding transcriptional regulator%3B acts together with PspC to induce psp operon during infection with phage%2C exposure to ethanol or osmotic shock%3B forms a complex with PspA and C%3B PspC is required for PspAB binding gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07710 AFK63_RS07715 AFK63_07730 AFK63_RS07715 1660954 1661310 + phage shock protein C with PsbB forms toxin/antitoxin pair%3B activates the psp operon in response to phage infection%2C exposure to ethanol or osmotic shock gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07715 AFK63_RS07720 AFK63_07735 AFK63_RS07720 1661355 1661597 + phage-shock protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07720 AFK63_RS07725 AFK63_07740 AFK63_RS07725 1661774 1663489 + sugar phosphorylase gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07725 AFK63_RS07730 AFK63_07745 AFK63_RS07730 1663501 1664793 + sugar ABC transporter substrate-binding protein gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07730 AFK63_RS07735 AFK63_07750 AFK63_RS07735 1664817 1665698 + sugar ABC transporter permease gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07735 AFK63_RS07740 AFK63_07755 AFK63_RS07740 1665685 1666527 + sugar ABC transporter permease gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07740 AFK63_RS07745 AFK63_07760 AFK63_RS07745 1666553 1667602 + alcohol dehydrogenase gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07745 AFK63_RS07750 AFK63_07765 AFK63_RS07750 1667621 1668361 + hypothetical protein gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07750 AFK63_RS07755 AFK63_07770 AFK63_RS07755 1669599 1669850 - excisionase gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07755 AFK63_RS07760 AFK63_07775 AFK63_RS07760 1669931 1671031 - bacteriophage protein gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07760 AFK63_RS07765 AFK63_07780 AFK63_RS07765 1671033 1671323 - host-nuclease inhibitor protein gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07765 AFK63_RS07770 AFK63_07785 AFK63_RS07770 1671810 1672217 - transcriptional regulator gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07770 AFK63_RS07775 AFK63_07790 AFK63_RS07775 1672296 1672535 + transcriptional regulator gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07775 AFK63_RS07780 AFK63_07795 AFK63_RS07780 1672535 1672987 + hypothetical protein gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07780 AFK63_RS07785 AFK63_07800 AFK63_RS07785 1673026 1673895 + hypothetical protein gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07785 AFK63_RS07790 AFK63_07805 AFK63_RS07790 1676448 1676663 + hypothetical protein gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07790 AFK63_RS07795 AFK63_07810 AFK63_RS07795 1676820 1677275 + hypothetical protein DLP12 prophage gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07795 AFK63_RS07800 AFK63_07815 AFK63_RS07800 1677278 1677478 + hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07800 AFK63_RS07805 AFK63_07820 AFK63_RS07805 1677469 1677765 + hypothetical protein gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07805 AFK63_RS07810 AFK63_07825 AFK63_RS07810 1677762 1678124 + Holliday junction DNA helicase / Crossover junction endodeoxyribonuclease rusA gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07810 AFK63_RS07815 AFK63_07830 AFK63_RS07815 1678121 1678816 + antiterminator gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07815 AFK63_RS07820 AFK63_07835 AFK63_RS07820 1678950 1679183 + hypothetical protein gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07820 AFK63_RS07825 AFK63_07840 AFK63_RS07825 1679675 1679890 + phage lysis protein S gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07825 AFK63_RS07830 AFK63_07845 AFK63_RS07830 1679890 1680375 + lysozyme gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07830 AFK63_RS07835 AFK63_07850 AFK63_RS07835 1680375 1680725 + lipoprotein gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07835 AFK63_RS07840 AFK63_07855 AFK63_RS07840 1681263 1681514 + hypothetical protein gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07840 AFK63_RS07845 AFK63_07865 AFK63_RS07845 1683837 1684265 + terminase gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07845 AFK63_RS07850 AFK63_07870 AFK63_RS07850 1684269 1685996 + terminase gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07850 AFK63_RS07855 AFK63_07875 AFK63_RS07855 1686142 1687383 + phage portal protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07855 AFK63_RS07860 AFK63_07880 AFK63_RS07860 1687376 1687999 + peptidase gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07860 AFK63_RS07865 AFK63_07885 AFK63_RS07865 1688076 1689296 + phage capsid protein gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07865 AFK63_RS07870 AFK63_07895 AFK63_RS07870 1689603 1689920 + phage gp6-like head-tail connector family protein gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07870 AFK63_RS07875 AFK63_07900 AFK63_RS07875 1689917 1690312 + phage head-tail adapter protein gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07875 AFK63_RS07880 AFK63_07905 AFK63_RS07880 1690305 1690823 + hypothetical protein gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07880 AFK63_RS07885 AFK63_07910 AFK63_RS07885 1690820 1691380 + transposase gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07885 AFK63_RS07890 AFK63_07915 AFK63_RS07890 1691542 1693383 + phage tail sheath protein gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07890 AFK63_RS07895 AFK63_07920 AFK63_RS07895 1693376 1693732 + phage tail tube protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07895 AFK63_RS07900 AFK63_07925 AFK63_RS07900 1693729 1694055 + phage small tail protein E gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07900 AFK63_RS07905 AFK63_07930 AFK63_RS07905 1694143 1696056 + phage tail tape measure protein gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07905 AFK63_RS07910 AFK63_07935 AFK63_RS07910 1696092 1697411 + DNA circularization protein gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07910 AFK63_RS07915 AFK63_07940 AFK63_RS07915 1697408 1698472 + baseplate protein gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07915 AFK63_RS07920 AFK63_07945 AFK63_RS07920 1698472 1699056 + phage baseplate assembly protein gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07920 AFK63_RS07925 AFK63_07950 AFK63_RS07925 1699060 1699476 + hypothetical protein gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07925 AFK63_RS07930 AFK63_07955 AFK63_RS07930 1699469 1700872 + phage baseplate protein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07930 AFK63_RS07935 AFK63_07960 AFK63_RS07935 1700863 1701435 + phage tail protein gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07935 AFK63_RS07940 AFK63_07965 AFK63_RS07940 1701491 1702714 + phage tail fiber protein gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07940 AFK63_RS07945 AFK63_07970 AFK63_RS07945 1702720 1703151 + tail fiber assembly protein gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07945 AFK63_RS07950 AFK63_07975 AFK63_RS07950 1703328 1703615 + hypothetical protein gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07950 AFK63_RS07955 AFK63_07980 AFK63_RS07955 1703867 1704220 + Arsenical resistance operon repressor regulates the expression of of the arsRBC involved in resistance to arsenic gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07955 AFK63_RS07960 AFK63_07985 AFK63_RS07960 1704310 1705593 + arsenical pump membrane protein gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07960 AFK63_RS07965 AFK63_07990 AFK63_RS07965 1705643 1706071 + arsenate reductase gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07965 AFK63_RS07970 AFK63_07995 AFK63_RS07970 1706138 1706851 - FMN reductase gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07970 AFK63_RS07975 AFK63_08000 AFK63_RS07975 1706857 1707189 - ArsR family transcriptional regulator gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07975 AFK63_RS07980 AFK63_08005 AFK63_RS07980 1707238 1708464 - hypothetical protein gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07980 AFK63_RS07985 AFK63_08010 AFK63_RS07985 1708461 1708988 - phosphinothricin acetyltransferase gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07985 AFK63_RS07990 AFK63_08015 AFK63_RS07990 1709087 1709992 + LysR family transcriptional regulator gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07990 AFK63_RS07995 AFK63_08020 AFK63_RS07995 1710489 1711541 + oxidoreductase gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS07995 AFK63_RS08000 AFK63_08025 AFK63_RS08000 1711538 1713799 + glycosyl hydrolase family 65 gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08000 AFK63_RS08005 AFK63_08030 AFK63_RS08005 1713781 1714464 + beta-phosphoglucomutase catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08005 AFK63_RS08010 AFK63_08035 AFK63_RS08010 1714474 1715556 + sugar ABC transporter ATP-binding protein gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08010 AFK63_RS08015 AFK63_08040 AFK63_RS08015 1716118 1717038 + MarR family transcriptional regulator gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08015 AFK63_RS08020 AFK63_08045 AFK63_RS08020 1717375 1718367 - LacI family transcriptional regulator gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08020 AFK63_RS08025 AFK63_08050 AFK63_RS08025 1718531 1719931 + hypothetical protein gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08025 AFK63_RS08030 AFK63_08055 AFK63_RS08030 1719928 1720983 + hypothetical protein gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08030 AFK63_RS08035 AFK63_08060 AFK63_RS08035 1721132 1722694 + transcriptional regulator regulates genes involved in the biosynthesis and transport of aromatic amino acids gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08035 AFK63_RS08040 AFK63_08065 tpx tpx 1722744 1723250 - peroxidase antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08040 AFK63_RS08045 AFK63_08070 AFK63_RS08045 1723387 1724385 + L-alanine-DL-glutamate epimerase catalyzes the epimerization of L-alanyl-D-glutamate to L-alanyl-L-glutamate gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08045 AFK63_RS08050 AFK63_08075 AFK63_RS08050 1724367 1725080 - murein peptide amidase A gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08050 AFK63_RS08055 AFK63_08080 AFK63_RS08055 1725329 1726945 + peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08055 AFK63_RS08060 AFK63_08085 AFK63_RS08060 1727003 1727443 - hypothetical protein gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08060 AFK63_RS08065 AFK63_08090 AFK63_RS08065 1727566 1727763 + hypothetical protein gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08065 AFK63_RS08070 AFK63_08095 AFK63_RS08070 1728349 1730505 - ferrichrysobactin receptor gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08070 AFK63_RS08075 AFK63_08100 AFK63_RS08075 1730686 1732236 + enterochelin esterase gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08075 AFK63_RS08080 AFK63_08105 AFK63_RS08080 1732237 1732818 - hypothetical protein gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08080 AFK63_RS08085 AFK63_08110 AFK63_RS08085 1733060 1733317 + hypothetical protein gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08085 AFK63_RS08090 AFK63_08115 AFK63_RS08090 1733450 1733689 - stress-induced protein gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08090 AFK63_RS08095 AFK63_08120 AFK63_RS08095 1734429 1736180 - histidine kinase gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08095 AFK63_RS08100 AFK63_08125 AFK63_RS08100 1736389 1736580 - hypothetical protein gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08100 AFK63_RS08105 AFK63_08130 AFK63_RS08105 1736654 1736977 - hypothetical protein gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08105 AFK63_RS08110 AFK63_08135 AFK63_RS08110 1737434 1737637 + hypothetical protein gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08110 AFK63_RS08115 AFK63_08140 zntB zntB 1737702 1738685 + zinc transporter gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08115 AFK63_RS08120 AFK63_08145 AFK63_RS08120 1739213 1740145 - tRNA 2-thiocytidine biosynthesis protein TtcA TtcA%3B YdaO%3B catalyzes the thiolation of cytosine 32 in specific tRNAs%3B forms 2-thiocytidine (s(2)C) gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08120 AFK63_RS08125 AFK63_08150 AFK63_RS08125 1740431 1741543 + endonuclease/exonuclease/phosphatase gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08125 AFK63_RS08130 AFK63_08155 AFK63_RS08130 1741954 1742811 + dehydrogenase gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08130 AFK63_RS08135 AFK63_08160 AFK63_RS08135 1742828 1743895 + mannose-6-phosphate isomerase gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08135 AFK63_RS08140 AFK63_08165 AFK63_RS08140 1743892 1745688 - ATPase AAA gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08140 AFK63_RS08145 AFK63_08170 AFK63_RS08145 1745959 1747479 + aldehyde dehydrogenase gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08145 AFK63_RS08150 AFK63_08175 AFK63_RS08150 1747512 1748543 + alcohol dehydrogenase gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08150 AFK63_RS08155 AFK63_08180 AFK63_RS08155 1748886 1749929 + hypothetical protein gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08155 AFK63_RS08160 AFK63_08185 AFK63_RS08160 1749943 1753452 - pyruvate-flavodoxin oxidoreductase gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08160 AFK63_RS08165 AFK63_08190 AFK63_RS08165 1753730 1753996 + hypothetical protein gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08165 AFK63_RS08170 AFK63_08195 AFK63_RS08170 1753997 1754425 - heat-inducible protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08170 AFK63_RS08175 AFK63_08200 AFK63_RS08175 1754480 1755469 - lactate dehydrogenase fermentative%3B catalyzes the formationof pyruvate from lactate gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08175 AFK63_RS08180 AFK63_08205 AFK63_RS08180 1755681 1758323 + hypothetical protein gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08180 AFK63_RS08185 AFK63_08210 AFK63_RS08185 1758320 1758511 + hypothetical protein gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08185 AFK63_RS08190 AFK63_08215 AFK63_RS08190 1758524 1758844 + hypothetical protein gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08190 AFK63_RS08195 AFK63_08220 AFK63_RS08195 1758923 1759243 + hypothetical protein gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08195 AFK63_RS08200 AFK63_08225 AFK63_RS08200 1759304 1759909 - FMN-dependent NADH-azoreductase FMN-dependent%3B requires NADH%3B catalyzes the cleavage of azo bond in aromatic azo compounds gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08200 AFK63_RS08205 AFK63_08230 AFK63_RS08205 1760116 1764018 + ATP-dependent RNA helicase HrpA involved in the post-transcriptional processing of the daa operon mRNA%2C which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08205 AFK63_RS08210 AFK63_08235 AFK63_RS08210 1764180 1764836 - methyltransferase gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08210 AFK63_RS08215 AFK63_08240 AFK63_RS08215 1764878 1766302 - transporter gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08215 AFK63_RS08220 AFK63_08245 AFK63_RS08220 1766302 1767384 - DSBA oxidoreductase gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08220 AFK63_RS08225 AFK63_08250 AFK63_RS08225 1767423 1769078 - MFS transporter gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08225 AFK63_RS08230 AFK63_08255 AFK63_RS08230 1769078 1769509 - MarR family transcriptional regulator gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08230 AFK63_RS08235 AFK63_08260 AFK63_RS08235 1769699 1770187 + acetyltransferase gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08235 AFK63_RS08240 AFK63_08265 AFK63_RS08240 1770171 1770578 + glutathione transferase gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08240 AFK63_RS08245 AFK63_08270 AFK63_RS08245 1770579 1771901 - MFS transporter gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08245 AFK63_RS08250 AFK63_08275 AFK63_RS08250 1772307 1773110 + hypothetical protein gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08250 AFK63_RS08255 AFK63_08280 AFK63_RS08255 1773319 1774758 + aldehyde dehydrogenase NAD-linked gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08255 AFK63_RS08260 AFK63_08285 AFK63_RS08260 1774792 1775724 - pectin acetylesterase gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08260 AFK63_RS08265 AFK63_08290 AFK63_RS08265 1775830 1776360 + cytochrome b561 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08265 AFK63_RS08270 AFK63_08295 AFK63_RS08270 1776528 1777856 + MFS transporter gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08270 AFK63_RS08275 AFK63_08300 AFK63_RS08275 1777872 1778231 - hypothetical protein gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08275 AFK63_RS08280 AFK63_08305 AFK63_RS08280 1778508 1778728 + hypothetical protein gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08280 AFK63_RS08285 AFK63_08310 AFK63_RS08285 1778833 1779060 - hypothetical protein gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08285 AFK63_RS08290 AFK63_08315 AFK63_RS08290 1779899 1780174 + hypothetical protein gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08290 AFK63_RS08295 AFK63_08320 AFK63_RS08295 1780206 1781324 + S-(hydroxymethyl)glutathione dehydrogenase catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione%3B also catalyzes the formation of aldehyde or ketone from alcohols gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08295 AFK63_RS08300 AFK63_08325 AFK63_RS08300 1781498 1783195 + chemotaxis protein gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08300 AFK63_RS08305 AFK63_08330 AFK63_RS08305 1783393 1783893 + hypothetical protein gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08305 AFK63_RS08310 AFK63_08335 AFK63_RS08310 1784045 1785112 - NADH:flavin oxidoreductase gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08310 AFK63_RS08315 AFK63_08340 AFK63_RS08315 1785231 1786154 - LysR family transcriptional regulator gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08315 AFK63_RS08320 AFK63_08345 AFK63_RS08320 1786510 1787853 + hypothetical protein gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08320 AFK63_RS08325 AFK63_08350 AFK63_RS08325 1787898 1789409 + carboxylesterase gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08325 AFK63_RS08330 AFK63_08355 mdoD mdoD 1789968 1791623 + glucan biosynthesis protein D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08330 AFK63_RS08335 AFK63_08360 AFK63_RS08335 1791787 1792359 + ribosomal-protein-serine acetyltransferase gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08335 AFK63_RS08340 AFK63_08365 AFK63_RS08340 1792356 1793336 - acetyltransferase gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08340 AFK63_RS08345 AFK63_08370 AFK63_RS08345 1793508 1794101 + tellurite resistance methyltransferase TehB with TehA confers resistance to tellurite gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08345 AFK63_RS08350 AFK63_08375 AFK63_RS08350 1794317 1794985 + hypothetical protein gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08350 AFK63_RS08355 AFK63_08380 AFK63_RS08355 1795016 1796179 - benzoate transporter gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08355 AFK63_RS08360 AFK63_08385 AFK63_RS08360 1796274 1796804 + XRE family transcriptional regulator gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08360 AFK63_RS08365 AFK63_08390 AFK63_RS08365 1797040 1799004 + protease gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08365 AFK63_RS08370 AFK63_08395 AFK63_RS08370 1799210 1799629 + DNA polymerase V subunit UmuD gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08370 AFK63_RS08375 AFK63_08400 AFK63_RS08375 1799631 1800899 + DNA polymerase V subunit UmuC binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08375 AFK63_RS08380 AFK63_08405 AFK63_RS08380 1800854 1801579 - hypothetical protein gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08380 AFK63_RS08385 AFK63_08410 AFK63_RS08385 1801797 1802207 - hypothetical protein gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08385 AFK63_RS08390 AFK63_08415 AFK63_RS08390 1802738 1803097 + multidrug transporter with MdtI is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08390 AFK63_RS08395 AFK63_08420 AFK63_RS08395 1803084 1803413 + multidrug transporter with MdtJ is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08395 AFK63_RS08400 AFK63_08425 AFK63_RS08400 1803460 1804281 - serine protease gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08400 AFK63_RS08405 AFK63_08430 AFK63_RS08405 1804676 1806160 - peptidase M32 gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08405 AFK63_RS08410 AFK63_08435 AFK63_RS08410 1806234 1807484 - membrane protein gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08410 AFK63_RS08415 AFK63_08440 AFK63_RS08415 1807606 1808526 + LysR family transcriptional regulator gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08415 AFK63_RS08420 AFK63_08445 AFK63_RS08420 1808633 1809850 + transcriptional regulator mlc%2C controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems%2C regulates genes involved in the uptake of sugars gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08420 AFK63_RS08425 AFK63_08450 AFK63_RS08425 1809966 1810657 + dethiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08425 AFK63_RS08430 AFK63_08455 AFK63_RS08430 1810876 1812024 - glycine/betaine ABC transporter ATP-binding protein gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08430 AFK63_RS08435 AFK63_08460 AFK63_RS08435 1812024 1812671 - choline ABC transporter permease gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08435 AFK63_RS08440 AFK63_08465 AFK63_RS08440 1812681 1813583 - glycine/betaine ABC transporter substrate-binding protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08440 AFK63_RS08445 AFK63_08470 AFK63_RS08445 1813600 1814313 - glycine/betaine ABC transporter permease gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08445 AFK63_RS08450 AFK63_08475 AFK63_RS08450 1814643 1814978 + membrane protein gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08450 AFK63_RS08455 AFK63_08480 AFK63_RS08455 1814975 1815583 - twin-argninine leader-binding protein DmsD binds to the twin-arginine signal peptides of certain proteins%2C including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08455 AFK63_RS08460 AFK63_08485 AFK63_RS08460 1815628 1816476 - dimethyl sulfoxide reductase gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08460 AFK63_RS08465 AFK63_08490 AFK63_RS08465 1816478 1817095 - dimethyl sulfoxide reductase oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08465 AFK63_RS08470 AFK63_08495 AFK63_RS08470 1817105 1819540 - dimethyl sulfoxide reductase gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08470 AFK63_RS08475 AFK63_08500 AFK63_RS08475 1819826 1820122 - membrane protein gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08475 AFK63_RS08480 AFK63_08505 AFK63_RS08480 1820238 1820945 + lipoprotein gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08480 AFK63_RS08485 AFK63_08510 AFK63_RS08485 1821000 1821560 - spermidine acetyltransferase catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08485 AFK63_RS08490 AFK63_08515 AFK63_RS08490 1821627 1821956 - hypothetical protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08490 AFK63_RS08495 AFK63_08520 AFK63_RS08495 1822073 1822399 + membrane protein gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08495 AFK63_RS08500 AFK63_08525 AFK63_RS08500 1822556 1823770 + bifunctional D-altronate/D-mannonate dehydratase starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08500 AFK63_RS08505 AFK63_08530 AFK63_RS08505 1823821 1825098 + hexuronate transporter involved in the transport of aldohexuronates gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08505 AFK63_RS08510 AFK63_08535 AFK63_RS08510 1825263 1826729 + D-mannonate oxidoreductase gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08510 AFK63_RS08515 AFK63_08540 AFK63_RS08515 1826901 1827104 - selenoprotein YdfZ gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08515 AFK63_RS08520 AFK63_08545 AFK63_RS08520 1827229 1828125 - hypothetical protein gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08520 AFK63_RS08525 AFK63_08550 AFK63_RS08525 1828159 1828845 - GntR family transcriptional regulator gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08525 AFK63_RS08530 AFK63_08555 AFK63_RS08530 1828937 1829683 - malonic semialdehyde reductase NADP(+)-dependent%3B catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde%2C catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine%3B can also use 3-hydroxybutyrate%2C 3-hydroxy-isobutyrate%2C D-threonine%2C L-allo-threonine%2CD-serine gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08530 AFK63_RS08535 AFK63_08560 AFK63_RS08535 1829844 1831889 + dipeptidyl carboxypeptidase II gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08535 AFK63_RS08540 AFK63_08565 AFK63_RS08540 1832215 1833018 - MerR family transcriptional regulator gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08540 AFK63_RS08545 AFK63_08570 AFK63_RS08545 1833181 1834092 - hypothetical protein gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08545 AFK63_RS08550 AFK63_08575 AFK63_RS08550 1834651 1834821 + stress-induced protein gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08550 AFK63_RS08555 AFK63_08580 AFK63_RS08555 1834936 1835709 + outer membrane or secreted lipoprotein gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08555 AFK63_RS08560 AFK63_08585 AFK63_RS08560 1835911 1837014 + methionine synthase gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08560 AFK63_RS08565 AFK63_08590 AFK63_RS08565 1837572 1839386 + allophanate hydrolase catalyzes the hydrolysis of allophanate gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08565 AFK63_RS08570 AFK63_08595 AFK63_RS08570 1839399 1843007 + urea carboxylase gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08570 AFK63_RS08575 AFK63_08600 AFK63_RS08575 1843192 1843893 + GntR family transcriptional regulator gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08575 AFK63_RS08580 AFK63_08605 AFK63_RS08580 1843930 1845201 + branched-chain amino acid ABC transporter substrate-binding protein gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08580 AFK63_RS08585 AFK63_08610 AFK63_RS08585 1845392 1846957 + urea ABC transporter permease gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08585 AFK63_RS08590 AFK63_08615 AFK63_RS08590 1846954 1848027 + amino acid ABC transporter permease gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08590 AFK63_RS08595 AFK63_08620 AFK63_RS08595 1848027 1848824 + urea ABC transporter ATP-binding protein gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08595 AFK63_RS08600 AFK63_08625 AFK63_RS08600 1848834 1849532 + urea ABC transporter ATP-binding protein gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08600 AFK63_RS08605 AFK63_08630 AFK63_RS08605 1849669 1850862 - transporter YdeF%3B uncharacterized member of the major facilitator superfamily (MFS) of transporters gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08605 AFK63_RS08610 AFK63_08635 AFK63_RS08610 1851071 1851967 + acetylserine transporter gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08610 AFK63_RS08615 AFK63_08640 AFK63_RS08615 1852005 1852208 - hypothetical protein gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08615 AFK63_RS08620 AFK63_08645 AFK63_RS08620 1852277 1852651 - transcriptional regulator transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype%3B also activates sodA%2C zwf and micF gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08620 AFK63_RS08625 AFK63_08650 AFK63_RS08625 1852670 1853104 - transcriptional regulator Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08625 AFK63_RS08630 AFK63_08655 AFK63_RS08630 1853352 1854551 - arabinose transporter gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08630 AFK63_RS08635 AFK63_08660 AFK63_RS08635 1854761 1855558 + isomerase gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08635 AFK63_RS08640 AFK63_08665 ldh ldh 1855592 1856536 - L-lactate dehydrogenase Converts (S)-lactate and NAD(+) to pyruvate and NADH gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08640 AFK63_RS08645 AFK63_08670 AFK63_RS08645 1856705 1857181 + GCN5 family acetyltransferase gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08645 AFK63_RS08650 AFK63_08675 AFK63_RS08650 1857138 1858013 - LysR family transcriptional regulator gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08650 AFK63_RS08655 AFK63_08680 AFK63_RS08655 1858152 1859540 + succinate dehydrogenase gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08655 AFK63_RS08660 AFK63_08685 AFK63_RS08660 1859758 1861347 + chemotaxis protein gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08660 AFK63_RS08665 AFK63_08690 AFK63_RS08665 1861395 1862321 + glutaminase catalyzes the formation of glutamate from glutamine gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08665 AFK63_RS08670 AFK63_08695 AFK63_RS08670 1862331 1862678 + hypothetical protein gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08670 AFK63_RS08675 AFK63_08700 AFK63_RS08675 1862797 1864242 + diguanylate cyclase gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08675 AFK63_RS08680 AFK63_08705 AFK63_RS08680 1864456 1865448 + diguanylate cyclase gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08680 AFK63_RS08685 AFK63_08710 AFK63_RS08685 1865518 1866489 + diguanylate cyclase gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08685 AFK63_RS08690 AFK63_08715 AFK63_RS08690 1866578 1867105 + GCN5 family acetyltransferase gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08690 AFK63_RS08695 AFK63_08720 AFK63_RS08695 1867223 1868674 + altronate oxidoreductase catalyzes the formation of D-tagaturonate from D-altronate gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08695 AFK63_RS08700 AFK63_08725 AFK63_RS08700 1868968 1870947 + lipase gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08700 AFK63_RS08705 AFK63_08730 treF treF 1871036 1872676 - trehalase cytoplasmic%3B catalyzes the hydrolysis of trehalose to glucose gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08705 AFK63_RS08710 AFK63_08735 AFK63_RS08710 1872821 1875028 - glycoside hydrolase gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08710 AFK63_RS08715 AFK63_08740 AFK63_RS08715 1875028 1877706 - PAS domain-containing two-component system sensor histidine kinase/response regulator gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08715 AFK63_RS08720 AFK63_08745 AFK63_RS08720 1877703 1878140 - hypothetical protein gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08720 AFK63_RS08725 AFK63_08750 AFK63_RS08725 1878137 1879534 - hypothetical protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08725 AFK63_RS08730 AFK63_08755 AFK63_RS08730 1879519 1881069 - hypothetical protein gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08730 AFK63_RS08735 AFK63_08760 AFK63_RS08735 1881066 1882406 - hypothetical protein gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08735 AFK63_RS08740 AFK63_08765 AFK63_RS08740 1882403 1884217 - cellulose synthase gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08740 AFK63_RS08745 AFK63_08770 AFK63_RS08745 1884546 1885766 + OpgC protein gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08745 AFK63_RS08750 AFK63_08775 AFK63_RS08750 1885781 1886695 + hypothetical protein gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08750 AFK63_RS08755 AFK63_08780 AFK63_RS08755 1886705 1887925 + transcriptional regulator gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08755 AFK63_RS08760 AFK63_08785 AFK63_RS08760 1887915 1888253 + anti-anti-sigma factor gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08760 AFK63_RS08765 AFK63_08790 AFK63_RS08765 1888258 1888689 + hypothetical protein gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08765 AFK63_RS08770 AFK63_08795 AFK63_RS08770 1888699 1889298 - XRE family transcriptional regulator gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08770 AFK63_RS08775 AFK63_08800 AFK63_RS08775 1889342 1890031 + hypothetical protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08775 AFK63_RS08780 AFK63_08805 AFK63_RS08780 1890051 1890560 + hypothetical protein gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08780 AFK63_RS08785 AFK63_08810 AFK63_RS08785 1890585 1890815 + acyl carrier protein gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08785 AFK63_RS08790 AFK63_08815 AFK63_RS08790 1891202 1892089 - alpha/beta hydrolase gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08790 AFK63_RS08795 AFK63_08820 AFK63_RS08795 1892172 1892540 + MerR family transcriptional regulator gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08795 AFK63_RS08800 AFK63_08825 AFK63_RS08800 1892823 1893392 + lipoprotein nlpC gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08800 AFK63_RS08805 AFK63_08830 AFK63_RS08805 1893394 1893720 - cupin gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08805 AFK63_RS08810 AFK63_08835 AFK63_RS08810 1893976 1894350 + hypothetical protein gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08810 AFK63_RS08815 AFK63_RS08815 AFK63_RS08815 1894357 1894659 - hypothetical protein gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08815 AFK63_RS08820 AFK63_08845 AFK63_RS08820 1894729 1895088 - hypothetical protein gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08820 AFK63_RS08825 AFK63_08850 AFK63_RS08825 1895185 1896486 - L-sorbosone dehydrogenase gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08825 AFK63_RS08830 AFK63_08855 AFK63_RS08830 1896499 1896924 - membrane protein gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08830 AFK63_RS08835 AFK63_08860 AFK63_RS08835 1897095 1898309 - signal transduction protein gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08835 AFK63_RS08840 AFK63_08865 AFK63_RS08840 1898535 1899671 - hypothetical protein gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08840 AFK63_RS08845 AFK63_08870 AFK63_RS08845 1899726 1900061 - hypothetical protein gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08845 AFK63_RS08850 AFK63_08875 AFK63_RS08850 1900209 1901183 + UV damage repair endonuclease UvdE gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08850 AFK63_RS08855 AFK63_08880 AFK63_RS08855 1901308 1902225 - hypothetical protein gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08855 AFK63_RS08860 AFK63_08885 AFK63_RS08860 1902240 1906367 - type IV secretion protein Rhs gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08860 AFK63_RS08865 AFK63_08890 AFK63_RS08865 1906524 1907066 - hypothetical protein gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08865 AFK63_RS08870 AFK63_08895 AFK63_RS08870 1907504 1907815 - hypothetical protein gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08870 AFK63_RS08875 AFK63_08900 AFK63_RS08875 1907828 1910044 - type IV secretion protein Rhs gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08875 AFK63_RS08880 AFK63_08905 AFK63_RS08880 1910472 1911407 - AraC family transcriptional regulator gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08880 AFK63_RS08885 AFK63_08910 AFK63_RS08885 1911593 1912330 + oxidoreductase gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08885 AFK63_RS08890 AFK63_08915 AFK63_RS08890 1912501 1913502 + alpha/beta hydrolase gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08890 AFK63_RS08895 AFK63_08920 AFK63_RS08895 1913624 1913821 + hypothetical protein gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08895 AFK63_RS08900 AFK63_08925 AFK63_RS08900 1913823 1914587 + hypothetical protein gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08900 AFK63_RS08905 AFK63_08930 AFK63_RS08905 1914651 1915244 + flavin reductase gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08905 AFK63_RS08910 AFK63_08935 AFK63_RS08910 1915416 1915832 - TfoX-like protein gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08910 AFK63_RS08915 AFK63_08940 AFK63_RS08915 1916292 1917056 + 3-oxoacyl-ACP reductase gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08915 AFK63_RS08920 AFK63_08945 AFK63_RS08920 1917102 1918187 - hydroxyacid dehydrogenase gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08920 AFK63_RS08925 AFK63_08950 AFK63_RS08925 1918348 1918884 - alkylhydroperoxidase gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08925 AFK63_RS08930 AFK63_08955 AFK63_RS08930 1919004 1919918 + AraC family transcriptional regulator gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08930 AFK63_RS08935 AFK63_08960 AFK63_RS08935 1919915 1920736 - N-hydroxyarylamine O-acetyltransferase gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08935 AFK63_RS08940 AFK63_08965 AFK63_RS08940 1921215 1921724 + hypothetical protein gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08940 AFK63_RS08945 AFK63_08970 AFK63_RS08945 1921798 1922703 + Mn-containing catalase gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08945 AFK63_RS08950 AFK63_08975 AFK63_RS08950 1922750 1922980 - Tautomerase PptA gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08950 AFK63_RS08955 AFK63_08980 AFK63_RS08955 1923251 1923895 + dihydropteridine reductase gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08955 AFK63_RS08960 AFK63_08985 ampC ampC 1923948 1925075 - class C beta-lactamase gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08960 AFK63_RS08965 AFK63_08990 AFK63_RS08965 1925408 1926865 + L-asparagine permease involved in the transporte of L-asparagine gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08965 AFK63_RS08970 AFK63_08995 AFK63_RS08970 1926989 1928035 + hypothetical protein gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08970 AFK63_RS08975 AFK63_09000 AFK63_RS08975 1928209 1929207 + sulfonate ABC transporter substrate-binding protein gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08975 AFK63_RS08980 AFK63_09005 AFK63_RS08980 1929235 1930142 + taurine dioxygenase gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08980 AFK63_RS08985 AFK63_09010 AFK63_RS08985 1930154 1930996 + sulfonate ABC transporter ATP-binding protein gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08985 AFK63_RS08990 AFK63_09015 AFK63_RS08990 1930956 1931822 + ABC transporter permease gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08990 AFK63_RS08995 AFK63_09020 AFK63_RS08995 1931852 1932910 - hypothetical protein gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS08995 AFK63_RS09000 AFK63_09025 AFK63_RS09000 1933182 1935296 + TonB-dependent receptor gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09000 AFK63_RS09005 AFK63_09030 AFK63_RS09005 1935413 1937017 + glycosidase gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09005 AFK63_RS09010 AFK63_09035 AFK63_RS09010 1937021 1938007 - short-chain dehydrogenase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09010 AFK63_RS09015 AFK63_09040 AFK63_RS09015 1938121 1940061 - hypothetical protein gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09015 AFK63_RS09020 AFK63_09045 AFK63_RS09020 1940272 1940451 - hypothetical protein gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09020 AFK63_RS09025 AFK63_09050 AFK63_RS09025 1940562 1941221 - GntR family transcriptional regulator gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09025 AFK63_RS09030 AFK63_09055 AFK63_RS09030 1941399 1942892 + ABC transporter substrate-binding protein gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09030 AFK63_RS09035 AFK63_09060 AFK63_RS09035 1942889 1943734 + peptide ABC transporter permease gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09035 AFK63_RS09040 AFK63_09065 AFK63_RS09040 1943734 1944648 + ABC transporter permease gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09040 AFK63_RS09045 AFK63_09070 AFK63_RS09045 1944645 1945991 + peptidase M20 gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09045 AFK63_RS09050 AFK63_09075 AFK63_RS09050 1946010 1946987 + ornithine cyclodeaminase gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09050 AFK63_RS09055 AFK63_RS09055 AFK63_RS09055 1946984 1947742 - peptide ABC transporter ATP-binding protein gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09055 AFK63_RS09060 AFK63_09085 AFK63_RS09060 1948673 1949713 - NADP-dependent oxidoreductase gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09060 AFK63_RS09065 AFK63_09090 AFK63_RS09065 1949763 1950338 - LacI family transcriptional regulator gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09065 AFK63_RS09070 AFK63_09095 AFK63_RS09070 1950377 1950895 + acetyltransferase gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09070 AFK63_RS09075 AFK63_09100 AFK63_RS09075 1950892 1951341 + membrane protein gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09075 AFK63_RS09080 AFK63_09105 AFK63_RS09080 1951345 1952229 - oxidoreductase gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09080 AFK63_RS09085 AFK63_09110 AFK63_RS09085 1952239 1952484 - hypothetical protein gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09085 AFK63_RS09090 AFK63_09115 AFK63_RS09090 1952532 1954127 - peptide ABC transporter substrate-binding protein DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09090 AFK63_RS09095 AFK63_09120 AFK63_RS09095 1954442 1955854 + ssrAB activated gene gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09095 AFK63_RS09100 AFK63_09125 AFK63_RS09100 1955858 1958845 + virulence factor SrfB gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09100 AFK63_RS09105 AFK63_09130 AFK63_RS09105 1958842 1961040 + virulence factor gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09105 AFK63_RS09110 AFK63_09135 AFK63_RS09110 1961072 1962262 - acyl-CoA thioesterase gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09110 AFK63_RS09115 AFK63_09140 AFK63_RS09115 1962568 1963089 + membrane protein gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09115 AFK63_RS09120 AFK63_09145 AFK63_RS09120 1963135 1964199 - AP endonuclease gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09120 AFK63_RS09125 AFK63_09150 AFK63_RS09125 1964429 1965967 + methyl-accepting chemotaxis protein gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09125 AFK63_RS09130 AFK63_09155 AFK63_RS09130 1966031 1967386 - esterase gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09130 AFK63_RS09135 AFK63_09160 AFK63_RS09135 1967487 1968335 - polyferredoxin gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09135 AFK63_RS09140 AFK63_09165 AFK63_RS09140 1968335 1969171 - dimethyl sulfoxide reductase subunit C gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09140 AFK63_RS09145 AFK63_09170 AFK63_RS09145 1969164 1969793 - 4Fe-4S ferredoxin gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09145 AFK63_RS09150 AFK63_09175 AFK63_RS09150 1969780 1972161 - DMSO reductase gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09150 AFK63_RS09155 AFK63_09180 AFK63_RS09155 1972324 1973520 - alcohol dehydrogenase gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09155 AFK63_RS09160 AFK63_09185 AFK63_RS09160 1973517 1975415 - spermidine dehydrogenase gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09160 AFK63_RS09165 AFK63_09190 AFK63_RS09165 1975519 1975719 - hypothetical protein gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09165 AFK63_RS09170 AFK63_09195 AFK63_RS09170 1975774 1976112 - hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09170 AFK63_RS09175 AFK63_09200 AFK63_RS09175 1976239 1976661 - hypothetical protein gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09175 AFK63_RS09180 AFK63_09205 AFK63_RS09180 1976658 1977101 - GNAT family acetyltransferase gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09180 AFK63_RS09185 AFK63_09210 AFK63_RS09185 1977363 1977719 - hypothetical protein gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09185 AFK63_RS09190 AFK63_09215 AFK63_RS09190 1977869 1979293 - gamma-aminobutyraldehyde dehydrogenase catalyzes the formation of 4-aminobutanoate from 4-aminobutanal%3B involved in putrescine degradation gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09190 AFK63_RS09195 AFK63_09220 AFK63_RS09195 1979311 1980117 - spermidine/putrescine ABC transporter permease gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09195 AFK63_RS09200 AFK63_09225 AFK63_RS09200 1980107 1981051 - spermidine/putrescine ABC transporter permease gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09200 AFK63_RS09205 AFK63_09230 AFK63_RS09205 1981053 1982063 - spermidine/putrescine ABC transporter ATP-binding protein gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09205 AFK63_RS09210 AFK63_09235 AFK63_RS09210 1982077 1983222 - spermidine/putrescine ABC transporter substrate-binding protein gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09210 AFK63_RS09215 AFK63_09240 AFK63_RS09215 1983592 1985034 - GntR family transcriptional regulator gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09215 AFK63_RS09220 AFK63_09245 AFK63_RS09220 1985232 1986641 + cytochrome D ubiquinol oxidase subunit I gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09220 AFK63_RS09225 AFK63_09250 AFK63_RS09225 1986641 1987651 + ubiquinol oxidase subunit II gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09225 AFK63_RS09230 AFK63_09255 AFK63_RS09230 1987937 1988506 + TetR family transcriptional regulator gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09230 AFK63_RS09235 AFK63_09260 AFK63_RS09235 1988510 1988839 + multidrug transporter gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09235 AFK63_RS09240 AFK63_09265 AFK63_RS09240 1989249 1990652 + GPH family transporter for arabinosides gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09240 AFK63_RS09245 AFK63_09270 AFK63_RS09245 1990665 1992185 + alpha-N-arabinofuranosidase gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09245 AFK63_RS09250 AFK63_09275 AFK63_RS09250 1992300 1993487 + porin gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09250 AFK63_RS09255 AFK63_09280 AFK63_RS09255 1993634 1995250 + ABC transporter substrate-binding protein gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09255 AFK63_RS09260 AFK63_09285 AFK63_RS09260 1995250 1996194 + peptide ABC transporter permease gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09260 AFK63_RS09265 AFK63_09290 AFK63_RS09265 1996194 1997042 + ABC transporter permease gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09265 AFK63_RS09270 AFK63_09295 AFK63_RS09270 1997042 1998652 + ABC transporter ATP-binding protein gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09270 AFK63_RS09275 AFK63_09300 AFK63_RS09275 1998649 1999698 + luciferase gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09275 AFK63_RS09280 AFK63_09305 AFK63_RS09280 1999695 2000788 + alkylhydroperoxidase gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09280 AFK63_RS09285 AFK63_09310 AFK63_RS09285 2000814 2001632 - sugar phosphatase gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09285 AFK63_RS09290 AFK63_09315 AFK63_RS09290 2001838 2002401 - DNA endonuclease SmrA gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09290 AFK63_RS09295 AFK63_09320 AFK63_RS09295 2003000 2003515 + cysteine methyltransferase gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09295 AFK63_RS09300 AFK63_09325 AFK63_RS09300 2003692 2004444 + fumarate/nitrate reduction transcriptional regulator Global transcription factor that controls the expression of over 100 target genes in response to anoxia gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09300 AFK63_RS09305 AFK63_09330 AFK63_RS09305 2004581 2005537 + universal stress protein UspE with UspC and UspD is involved in resistance to UV irradiation gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09305 AFK63_RS09310 AFK63_09335 pntB pntB 2005647 2007035 - pyridine nucleotide transhydrogenase catalyzes reversible transfer of hydride ion equivalent between NAD and NADP%3B membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane%3B forms a tetramer composed of two alpha and 2 beta subunits%3B AB-stereospecific enzyme gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09310 AFK63_RS09315 AFK63_09340 pntA pntA 2007046 2008578 - NAD(P) transhydrogenase subunit alpha forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane%3B involved in catalyzing transfer of hydride ion equivalents between NAD and NADP%3B stereospecific (AB-specific)%3B functions as a proton pump by translocating protons from cytoplasm to periplasm gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09315 AFK63_RS09320 AFK63_09345 AFK63_RS09320 2009104 2010048 + hypothetical protein gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09320 AFK63_RS09325 AFK63_09350 AFK63_RS09325 2010234 2011616 + arginine:ornithine antiporter gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09325 AFK63_RS09330 AFK63_09355 AFK63_RS09330 2011647 2012369 + dihydromonapterin reductase gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09330 AFK63_RS09335 AFK63_09360 AFK63_RS09335 2012445 2013170 + two-component system response regulator response regulator in two-component regulatory system with RstB gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09335 AFK63_RS09340 AFK63_09365 AFK63_RS09340 2013208 2013960 - oxidoreductase gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09340 AFK63_RS09345 AFK63_09370 AFK63_RS09345 2014072 2014977 + LysR family transcriptional regulator gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09345 AFK63_RS09350 AFK63_09375 AFK63_RS09350 2015004 2016290 + two-component system sensor histidine kinase gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09350 AFK63_RS09355 AFK63_09380 AFK63_RS09355 2016696 2017625 + DNA replication terminus site-binding protein binds to DNA replication terminator sequences to prevent passage of replication forks gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09355 AFK63_RS09360 AFK63_09385 fumC fumC 2017626 2019023 - fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09360 AFK63_RS09365 AFK63_09390 AFK63_RS09365 2019244 2020890 - fumarate hydratase catalyzes the formation of malate from fumerate gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09365 AFK63_RS09370 AFK63_09395 AFK63_RS09370 2021096 2022274 + mannose-6-phosphate isomerase catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09370 AFK63_RS09375 AFK63_09400 AFK63_RS09375 2022374 2023951 + hypothetical protein gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09375 AFK63_RS09380 AFK63_09405 AFK63_RS09380 2023994 2025022 - transcriptional regulator regulates malXY which are involved in maltose-glucose transport gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09380 AFK63_RS09385 AFK63_09410 AFK63_RS09385 2025195 2026784 + bifunctional PTS system maltose and glucose-specific transporter subunits IICB phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%3B catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane%3B component IIB catalyzes the phosphorylation of the sugar molecule%3B IIC forms the translocation channel and contains the substrate specific binding site gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09385 AFK63_RS09390 AFK63_09415 AFK63_RS09390 2026799 2027968 + bifunctional beta-cystathionase/maltose regulon regulatory protein catalyzes the formation of homocysteine and pyruvate from cystathionine%3B also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09390 AFK63_RS09395 AFK63_09420 AFK63_RS09395 2028074 2029075 + adenosine deaminase gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09395 AFK63_RS09400 AFK63_09425 AFK63_RS09400 2029091 2030089 - hypothetical protein gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09400 AFK63_RS09405 AFK63_09430 AFK63_RS09405 2030253 2031296 - oxidoreductase gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09405 AFK63_RS09410 AFK63_09435 AFK63_RS09410 2031932 2032147 + nucleoid-associated protein YdgT%3B in E. coli%2C when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC%3B seems to play a role in optimizing the activity of oriC%3B non-essential%3B Hha protein paralog%3B in an hha mutant background%2C cnu is overexpressed and can compensate hha-induced phenotypes gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09410 AFK63_RS09415 AFK63_09440 AFK63_RS09415 2032242 2032685 + membrane protein gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09415 AFK63_RS09420 AFK63_09445 AFK63_RS09420 2032760 2033341 + electron transport complex subunit A gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09420 AFK63_RS09425 AFK63_09450 AFK63_RS09425 2033341 2033919 + electron transporter RnfB part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09425 AFK63_RS09430 AFK63_09455 AFK63_RS09430 2033912 2036218 + electron transporter RnfC part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09430 AFK63_RS09435 AFK63_09460 rnfD rnfD 2036219 2037271 + electron transporter RnfD RnfD%3B RsxD%3B required for nitrogen fixation in Rhodobacter capsulatus%3B part of a membrane-bound complex thought to be involved in electron transport to nitrogenase%3B in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09435 AFK63_RS09440 AFK63_09465 AFK63_RS09440 2037281 2037910 + electron transporter RnfG part of membrane-bound complex hought to be involved in electron transport to nitrogen gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09440 AFK63_RS09445 AFK63_09470 AFK63_RS09445 2037903 2038589 + elongation factor G gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09445 AFK63_RS09450 AFK63_09475 AFK63_RS09450 2038586 2039221 + endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09450 AFK63_RS09455 AFK63_09480 tppB tppB 2039812 2041311 + peptide ABC transporter permease mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09455 AFK63_RS09460 AFK63_09485 AFK63_RS09460 2041420 2042028 + glutathione S-transferase gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09460 AFK63_RS09465 AFK63_09490 AFK63_RS09465 2042069 2042929 - pyridoxamine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09465 AFK63_RS09470 AFK63_09495 AFK63_RS09470 2043004 2044278 - tyrosyl-tRNA synthetase gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09470 AFK63_RS09475 AFK63_09500 AFK63_RS09475 2044418 2045074 - pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09475 AFK63_RS09480 AFK63_09505 AFK63_RS09480 2045131 2045454 - lysozyme inhibitor MliC%3B membrane-bound lysozyme inhibitor of c-type lysozyme gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09480 AFK63_RS09485 AFK63_09510 anmK anmK 2045510 2046664 - anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1%2C6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate%3B involved in murein recycling gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09485 AFK63_RS09490 AFK63_09515 AFK63_RS09490 2046941 2047408 + membrane protein gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09490 AFK63_RS09495 AFK63_09520 AFK63_RS09495 2047522 2047962 - SlyA family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09495 AFK63_RS09500 AFK63_09525 AFK63_RS09500 2048139 2048375 + membrane protein gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09500 AFK63_RS09505 AFK63_09530 AFK63_RS09505 2048380 2049237 + membrane protein gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09505 AFK63_RS09510 AFK63_09535 AFK63_RS09510 2049249 2051282 + fusaric acid resistance protein gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09510 AFK63_RS09515 AFK63_09540 AFK63_RS09515 2051275 2051793 - superoxide dismutase SodC%3B copper and zinc binding%3B converts superoxide radicals to hydrogen peroxide and water gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09515 AFK63_RS09520 AFK63_09545 AFK63_RS09520 2051874 2052770 - oxidoreductase gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09520 AFK63_RS09525 AFK63_09550 AFK63_RS09525 2052824 2053063 - oxidoreductase gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09525 AFK63_RS09530 AFK63_09555 AFK63_RS09530 2053271 2054899 + hydrolase gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09530 AFK63_RS09535 AFK63_09560 AFK63_RS09535 2054964 2055545 + transcriptional regulator represses nemA which is involved in degradation of N-ethylmaleimide gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09535 AFK63_RS09540 AFK63_09565 AFK63_RS09540 2055618 2056715 + N-ethylmaleimide reductase FMN-linked%3B catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09540 AFK63_RS09545 AFK63_09570 AFK63_RS09545 2056807 2057214 + glyoxalase I Ni-dependent%3B catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09545 AFK63_RS09550 AFK63_09575 AFK63_RS09550 2057310 2057981 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09550 AFK63_RS09555 AFK63_09580 AFK63_RS09555 2058048 2058395 - glutaredoxin gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09555 AFK63_RS09560 AFK63_09585 AFK63_RS09560 2058740 2059567 + endopeptidase gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09560 AFK63_RS09565 AFK63_09590 AFK63_RS09565 2059631 2060797 - MFS transporter gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09565 AFK63_RS09570 AFK63_09595 AFK63_RS09570 2061445 2062470 + purine nucleotide synthesis repressor binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09570 AFK63_RS09575 AFK63_09600 AFK63_RS09575 2062489 2063403 - transcriptional regulator gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09575 AFK63_RS09580 AFK63_09605 AFK63_RS09580 2063515 2064678 + Bcr/CflA family drug resistance efflux transporter uncharacterized member of the major facilitator superfamily (MFS) gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09580 AFK63_RS09585 AFK63_09610 AFK63_RS09585 2064978 2066126 + cyclopropane fatty acyl phospholipid synthase catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09585 AFK63_RS09590 AFK63_09615 AFK63_RS09590 2066321 2067640 + cytochrome C biogenesis protein CcmF gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09590 AFK63_RS09595 AFK63_09620 AFK63_RS09595 2067695 2069080 + 6-phospho-beta-glucosidase gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09595 AFK63_RS09600 AFK63_09625 AFK63_RS09600 2069125 2070045 + LacI family transcriptional regulator gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09600 AFK63_RS09605 AFK63_09630 AFK63_RS09605 2070063 2070713 - riboflavin synthase subunit alpha catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09605 AFK63_RS09610 AFK63_09635 AFK63_RS09610 2070950 2072323 + MATE family efflux transporter NorM%3B MdtK%3B functions as a Na(+)/drug antiporter%3B inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09610 AFK63_RS09615 AFK63_09640 AFK63_RS09615 2072524 2072600 + tRNA-Val tRNA gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09615 AFK63_RS09620 AFK63_09645 AFK63_RS09620 2072610 2072686 + tRNA-Val tRNA gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09620 AFK63_RS09625 AFK63_09650 AFK63_RS09625 2072941 2073483 - hypothetical protein gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09625 AFK63_RS09630 AFK63_09655 AFK63_RS09630 2073622 2073915 - hypothetical protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09630 AFK63_RS09635 AFK63_09660 AFK63_RS09635 2074234 2075010 + hypothetical protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09635 AFK63_RS09640 AFK63_09665 AFK63_RS09640 2075097 2076098 + AraC family transcriptional regulator gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09640 AFK63_RS09645 AFK63_09670 AFK63_RS09645 2076121 2076798 - hypothetical protein gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09645 AFK63_RS09650 AFK63_09675 AFK63_RS09650 2077180 2077585 + tolA family protein gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09650 AFK63_RS09655 AFK63_09680 AFK63_RS09655 2077643 2078104 - membrane protein gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09655 AFK63_RS09660 AFK63_09685 AFK63_RS09660 2078267 2078650 + MarR family transcriptional regulator gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09660 AFK63_RS09665 AFK63_09690 AFK63_RS09665 2078688 2079353 - hypothetical protein gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09665 AFK63_RS09670 AFK63_09695 AFK63_RS09670 2079420 2081450 - choline transporter proton-motive-force-driven choline transporter gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09670 AFK63_RS09675 AFK63_09700 AFK63_RS09675 2081698 2082294 + BetI family transcriptional regulator HTH-type%3B bet1%3B Repressor involved in choline regulation of the bet genes gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09675 AFK63_RS09680 AFK63_09705 AFK63_RS09680 2082307 2083779 + betaine-aldehyde dehydrogenase gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09680 AFK63_RS09685 AFK63_09710 AFK63_RS09685 2083806 2085485 + choline dehydrogenase catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09685 AFK63_RS09690 AFK63_09715 AFK63_RS09690 2085562 2086449 - LysR family transcriptional regulator gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09690 AFK63_RS09695 AFK63_09720 AFK63_RS09695 2086588 2087433 + MBL fold metallo-hydrolase gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09695 AFK63_RS09700 AFK63_09725 AFK63_RS09700 2087458 2087874 - aldehyde-activating protein gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09700 AFK63_RS09705 AFK63_09730 AFK63_RS09705 2088201 2088545 + hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09705 AFK63_RS09710 AFK63_09735 AFK63_RS09710 2088591 2088809 - hypothetical protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09710 AFK63_RS09715 AFK63_09740 AFK63_RS09715 2088907 2090289 - transporter gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09715 AFK63_RS09720 AFK63_09745 AFK63_RS09720 2090418 2091332 + LysR family transcriptional regulator gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09720 AFK63_RS09725 AFK63_09750 AFK63_RS09725 2091393 2093072 - formate dehydrogenase gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09725 AFK63_RS09730 AFK63_09755 AFK63_RS09730 2093121 2093540 - spermidine/putrescine ABC transporter substrate-binding protein gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09730 AFK63_RS09735 AFK63_09760 AFK63_RS09735 2093709 2094731 - nickel transporter gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09735 AFK63_RS09740 AFK63_09765 AFK63_RS09740 2094725 2096965 - carbamoyl phosphate phosphatase carbamoyltransferase%3B involved in the formation of the cyanate group of hydrogenase%3B catalyzes the formation of carbamoyladenylate from carbamoylphosphate and then transfers the carbamoyl group to HypE gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09740 AFK63_RS09745 AFK63_09770 AFK63_RS09745 2097014 2099164 - formate dehydrogenase selenocysteine-containing polypeptide%3B hydrogen linked formate dehydrogenase which catalyzes the oxidation of formate gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09745 AFK63_RS09750 AFK63_09775 AFK63_RS09750 2099199 2099744 - formate dehydrogenase involved in electron transport from formate to hydrogen gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09750 AFK63_RS09755 AFK63_09780 AFK63_RS09755 2099948 2100169 - glycogen synthase gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09755 AFK63_RS09760 AFK63_09785 hycI hycI 2100846 2101319 - hydrogenase 3 maturation protease involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09760 AFK63_RS09765 AFK63_09790 AFK63_RS09765 2101312 2101719 - formate hydrogenlyase maturation protein HycH required for the maturation of the formate hydrogenlyase complex gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09765 AFK63_RS09770 AFK63_09795 AFK63_RS09770 2101716 2102483 - formate hydrogenlyase gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09770 AFK63_RS09775 AFK63_09800 AFK63_RS09775 2102480 2103022 - formate hydrogenlyase complex iron-sulfur subunit electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09775 AFK63_RS09780 AFK63_09805 hycE hycE 2103148 2104857 - hydrogenase 3 large subunit formate hydrogenlyase subunit 5%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09780 AFK63_RS09785 AFK63_09810 hycD hycD 2104873 2105799 - hydrogenase 3 membrane subunit formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09785 AFK63_RS09790 AFK63_09815 AFK63_RS09790 2105801 2107627 - formate hydrogenlyase subunit 3 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen%3B formate hydrogenlyase comprises of a formate dehydrogenase%2C unidentified electron carriers and a hydrogenase (subunit 3) gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09790 AFK63_RS09795 AFK63_09820 AFK63_RS09795 2107624 2108232 - formate hydrogenlyase gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09795 AFK63_RS09800 AFK63_09825 AFK63_RS09800 2108314 2108778 - formate hydrogenlyase regulatory protein HycA regulates several genes involved in the formate hydrogenlyase system%3B seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09800 AFK63_RS09805 AFK63_09830 AFK63_RS09805 2108998 2109348 + hydrogenase nickel incorporation protein gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09805 AFK63_RS09810 AFK63_09835 AFK63_RS09810 2109352 2110224 + hydrogenase nickel incorporation protein HypB GTP hydrolase involved in nickel liganding into hydrogenases gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09810 AFK63_RS09815 AFK63_09840 AFK63_RS09815 2110215 2110493 + hydrogenase assembly chaperone HypC%3B accessory protein necessary for maturation of the hydrogenase isoforms 1%2C 2 and 3%3B forms a complex with HypD%2C HypE%2C and HypF proteins%2C which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09815 AFK63_RS09820 AFK63_09845 AFK63_RS09820 2110493 2111614 + hydrogenase isoenzymes formation protein HypD necessary for the synthesis of all three hydrogenase isoenzymes gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09820 AFK63_RS09825 AFK63_09850 AFK63_RS09825 2111611 2112621 + carbamoyl dehydratase HypE hydrogenase isoenzymes formation protein%3B involved in the formation of the cyanate group of the large subunit of the hydrogenase%3B catalyzes the formation of thiocyanate from thiocarbamate gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09825 AFK63_RS09830 AFK63_09855 AFK63_RS09830 2112715 2114790 + transcriptional regulator regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09830 AFK63_RS09835 AFK63_09860 AFK63_RS09835 2114853 2116214 - putrescine importer PuuP gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09835 AFK63_RS09840 AFK63_09865 AFK63_RS09840 2116604 2118022 - gamma-glutamylputrescine synthetase gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09840 AFK63_RS09845 AFK63_09870 AFK63_RS09845 2118236 2119003 + gamma-glutamyl-gamma-aminobutyrate hydrolase gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09845 AFK63_RS09850 AFK63_09875 AFK63_RS09850 2119028 2119585 + transcriptional regulator regulates genes involved in putrescine degradation gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09850 AFK63_RS09855 AFK63_09880 AFK63_RS09855 2119752 2121251 + aldehyde dehydrogenase gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09855 AFK63_RS09860 AFK63_09885 AFK63_RS09860 2121244 2122524 + gamma-glutamylputrescine oxidoreductase catalyzes the formation of gamma-glutamyl-gamma-aminobutyraldehyde from gamma-glutamylputrescine gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09860 AFK63_RS09865 AFK63_09890 AFK63_RS09865 2123078 2131072 - hypothetical protein gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09865 AFK63_RS09870 AFK63_09895 AFK63_RS09870 2131104 2132366 - glycosyl transferase gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09870 AFK63_RS09875 AFK63_09900 AFK63_RS09875 2133373 2134785 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09875 AFK63_RS09880 AFK63_09905 AFK63_RS09880 2135098 2135334 + murein lipoprotein major outer membrane lipoprotein%3B interacts with peptidoglycan to maintain the integrity of the cell envelope gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09880 AFK63_RS09885 AFK63_09910 AFK63_RS09885 2135496 2136518 - peptidoglycan-binding protein LysM gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09885 AFK63_RS09890 AFK63_09915 AFK63_RS09890 2136614 2137030 - cysteine desufuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09890 AFK63_RS09895 AFK63_09920 AFK63_RS09895 2137042 2138262 - cysteine sulfinate desulfinase gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09895 AFK63_RS09900 AFK63_09925 AFK63_RS09900 2138259 2139533 - Fe-S cluster assembly protein SufD with SufBC activates cysteine desulfurase SufS gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09900 AFK63_RS09905 AFK63_09930 sufC sufC 2139508 2140254 - Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09905 AFK63_RS09910 AFK63_09935 AFK63_RS09910 2140275 2141765 - Fe-S cluster assembly protein SufB with SufCD activates cysteine desulfurase SufS gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09910 AFK63_RS09915 AFK63_09940 sufA sufA 2141768 2142145 - (Fe-S)-cluster assembly protein functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09915 AFK63_RS09920 AFK63_09945 AFK63_RS09920 2142511 2142921 - thioesterase required for efficient enterobactin production gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09920 AFK63_RS09925 AFK63_09950 AFK63_RS09925 2142918 2145974 - hypothetical protein gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09925 AFK63_RS09930 AFK63_09955 AFK63_RS09930 2146189 2147307 + hypothetical protein YdiK%3B inner membrane protein%3B ydiK promoter presents a PurR sequence%2C suggesting that its expression is purine-regulated%3B unknown function gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09930 AFK63_RS09935 AFK63_09960 AFK63_RS09935 2147611 2149980 - beta-D-glucoside glucohydrolase gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09935 AFK63_RS09940 AFK63_09965 AFK63_RS09940 2149984 2151372 - symporter YagG uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09940 AFK63_RS09945 AFK63_09970 AFK63_RS09945 2151593 2153971 - phosphoenolpyruvate synthase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09945 AFK63_RS09950 AFK63_09975 AFK63_RS09950 2154306 2155139 + PEP synthetase regulatory protein gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09950 AFK63_RS09955 AFK63_09980 AFK63_RS09955 2155294 2156340 + phospho-2-dehydro-3-deoxyheptonate aldolase gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09955 AFK63_RS09960 AFK63_09985 AFK63_RS09960 2156401 2157849 - hypothetical protein gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09960 AFK63_RS09965 AFK63_09990 AFK63_RS09965 2157911 2158630 - cyclic di-GMP regulator CdgR gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09965 AFK63_RS09970 AFK63_09995 AFK63_RS09970 2159024 2160340 - diacetylchitobiose-6-phosphate hydrolase catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09970 AFK63_RS09975 AFK63_10000 AFK63_RS09975 2160507 2160971 - endopeptidase gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09975 AFK63_RS09980 AFK63_10005 AFK63_RS09980 2161049 2161795 - vitamin B12-transporter ATPase ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09980 AFK63_RS09985 AFK63_10010 btuE btuE 2161795 2162346 - glutathione peroxidase similar to glutathione peroxidase%3B member of the btuCED operon which is required for vitamin B12 transport across the inner membrane gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09985 AFK63_RS09990 AFK63_10015 AFK63_RS09990 2162378 2163379 - Vitamin B12 import system permease BtuC gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09990 AFK63_RS09995 AFK63_10020 ihfA ihfA 2163457 2163756 - integration host factor subunit alpha This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS09995 AFK63_RS10000 AFK63_10025 pheT pheT 2163761 2166148 - phenylalanine--tRNA ligase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10000 AFK63_RS10005 AFK63_10030 AFK63_RS10005 2166164 2167147 - phenylalanine--tRNA ligase subunit alpha gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10005 AFK63_RS10010 AFK63_10035 rplT rplT 2167534 2167890 - 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10010 AFK63_RS10015 AFK63_10040 AFK63_RS10015 2167938 2168135 - 50S ribosomal protein L35 gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10015 AFK63_RS10020 AFK63_10045 AFK63_RS10020 2168233 2168667 - translation initiation factor IF-3 gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10020 AFK63_RS10025 AFK63_10050 thrS thrS 2168779 2170707 - threonyl-tRNA synthetase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10025 AFK63_RS10030 AFK63_10055 AFK63_RS10030 2170985 2171461 - GCN5 family acetyltransferase gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10030 AFK63_RS10035 AFK63_10060 AFK63_RS10035 2171556 2172497 + LysR family transcriptional regulator gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10035 AFK63_RS10040 AFK63_10065 AFK63_RS10040 2172641 2173087 - GCN5-related N-acetyltransferase gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10040 AFK63_RS10045 AFK63_10070 AFK63_RS10045 2173771 2174280 - ecotin gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10045 AFK63_RS10050 AFK63_10075 AFK63_RS10050 2174462 2174911 - hypothetical protein gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10050 AFK63_RS10055 AFK63_10080 AFK63_RS10055 2175059 2175892 - catalase gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10055 AFK63_RS10060 AFK63_10085 AFK63_RS10060 2176246 2177751 - glycine/betaine ABC transporter gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10060 AFK63_RS10065 AFK63_10090 AFK63_RS10065 2178272 2178499 - hypothetical protein gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10065 AFK63_RS10070 AFK63_10095 AFK63_RS10070 2178775 2179533 - membrane protein gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10070 AFK63_RS10075 AFK63_10100 AFK63_RS10075 2179828 2180757 + 6-phosphofructokinase gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10075 AFK63_RS10080 AFK63_10105 AFK63_RS10080 2180810 2181106 + hypothetical protein gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10080 AFK63_RS10085 AFK63_10110 AFK63_RS10085 2181203 2182063 + hypothetical protein gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10085 AFK63_RS10090 AFK63_10115 AFK63_RS10090 2182093 2182629 - membrane protein gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10090 AFK63_RS10095 AFK63_10120 AFK63_RS10095 2182789 2183457 + 2-deoxyglucose-6-phosphatase YniC%3B catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate%2C mannose 6-phosphate and p-nitrophenyl phosphate gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10095 AFK63_RS10100 AFK63_10125 AFK63_RS10100 2183642 2184397 + 2-deoxy-D-gluconate 3-dehydrogenase catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10100 AFK63_RS10105 AFK63_10130 AFK63_RS10105 2184511 2185101 + membrane protein gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10105 AFK63_RS10110 AFK63_10135 AFK63_RS10110 2185237 2186628 + L-cystine transporter tcyP gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10110 AFK63_RS10115 AFK63_10140 AFK63_RS10115 2186788 2187018 - cell division modulator gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10115 AFK63_RS10120 AFK63_10145 katE katE 2187230 2189485 + hydroperoxidase Catalase HPII%3B monofunctional catalase that decomposes hydrogen peroxide into water and oxygen%3B serves to protect cells from the toxic effects of hydrogen peroxide gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10120 AFK63_RS10125 AFK63_10150 AFK63_RS10125 2189600 2189944 - transcriptional regulator osmotically-inducible lipoprotein E%3B activator of ntr-like gene protein gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10125 AFK63_RS10130 AFK63_10155 nadE nadE 2190199 2191026 + NAD synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10130 AFK63_RS10135 AFK63_10160 AFK63_RS10135 2191117 2192007 + aromatic amino acid exporter gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10135 AFK63_RS10140 AFK63_10165 AFK63_RS10140 2192076 2192951 + nucleotide excision repair endonuclease 3' incision activity%3B acts with UvrC gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10140 AFK63_RS10145 AFK63_10170 AFK63_RS10145 2192948 2193493 - hypothetical protein gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10145 AFK63_RS10150 AFK63_10175 AFK63_RS10150 2193775 2194257 - periplasmic protein periplasmic protein induced by stress response via Cpx and BaeSR system%3B similar to CpxP gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10150 AFK63_RS10155 AFK63_10180 AFK63_RS10155 2194555 2195514 - succinylglutamate desuccinylase gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10155 AFK63_RS10160 AFK63_10185 AFK63_RS10160 2195524 2196849 - succinylarginine dihydrolase catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine%2C ammonia and carbon dioxide in arginine degradation gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10160 AFK63_RS10165 AFK63_10190 astD astD 2196846 2198324 - succinylglutamate-semialdehyde dehydrogenase a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity%3B converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10165 AFK63_RS10170 AFK63_10195 AFK63_RS10170 2198321 2199358 - arginine succinyltransferase gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10170 AFK63_RS10175 AFK63_10200 AFK63_RS10175 2199355 2200575 - acetylornithine aminotransferase catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate%3B also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10175 AFK63_RS10180 AFK63_10205 AFK63_RS10180 2201016 2201822 + hypothetical protein gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10180 AFK63_RS10185 AFK63_10210 AFK63_RS10185 2201868 2202281 + pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10185 AFK63_RS10190 AFK63_10215 AFK63_RS10190 2202241 2202513 - hypothetical protein gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10190 AFK63_RS10195 AFK63_10220 AFK63_RS10195 2202643 2204589 - DNA topoisomerase III decatenates replicating daughter chromosomes gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10195 AFK63_RS10200 AFK63_10225 AFK63_RS10200 2204593 2205636 - selenophosphate synthase catalyzes the formation of selenophosphate from selenide and ATP gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10200 AFK63_RS10205 AFK63_10230 AFK63_RS10205 2205788 2206339 - oxidoreductase gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10205 AFK63_RS10210 AFK63_10235 AFK63_RS10210 2206514 2208364 + signal peptide peptidase SppA SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10210 AFK63_RS10215 AFK63_10240 ansA ansA 2208465 2209481 + asparaginase converts asparagine to aspartate and ammonia gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10215 AFK63_RS10220 AFK63_10245 AFK63_RS10220 2209492 2210133 + nicotinamidase/pyrazinamidase catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10220 AFK63_RS10225 AFK63_10250 AFK63_RS10225 2210207 2210485 - hypothetical protein gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10225 AFK63_RS10230 AFK63_10255 AFK63_RS10230 2210526 2210939 - methionine sulfoxide reductase B gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10230 AFK63_RS10235 AFK63_10260 AFK63_RS10235 2211284 2212279 + glyceraldehyde-3-phosphate dehydrogenase gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10235 AFK63_RS10240 AFK63_10265 AFK63_RS10240 2212356 2213243 + glucose-6-phosphate 1-epimerase gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10240 AFK63_RS10245 AFK63_10270 AFK63_RS10245 2213398 2214144 - MltA-interacting protein MipA scaffolding protein for the murein polymerase MrcB and the lytic transglycosylase MltA gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10245 AFK63_RS10250 AFK63_10275 AFK63_RS10250 2214579 2216513 + serine/threonine protein kinase gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10250 AFK63_RS10255 AFK63_10280 AFK63_RS10255 2216627 2217910 + hypothetical protein gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10255 AFK63_RS10260 AFK63_10285 AFK63_RS10260 2218193 2219713 + hypothetical protein gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10260 AFK63_RS10265 AFK63_10290 AFK63_RS10265 2220370 2220894 + hypothetical protein gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10265 AFK63_RS10270 AFK63_10295 AFK63_RS10270 2221074 2221520 + hypothetical protein gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10270 AFK63_RS10275 AFK63_10300 AFK63_RS10275 2221597 2222778 + membrane protein gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10275 AFK63_RS10280 AFK63_10305 AFK63_RS10280 2222782 2223489 - hypothetical protein gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10280 AFK63_RS10285 AFK63_10310 AFK63_RS10285 2223699 2224058 + MarR family transcriptional regulator gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10285 AFK63_RS10290 AFK63_10315 AFK63_RS10290 2224063 2224368 - periplasmic protein gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10290 AFK63_RS10295 AFK63_10320 AFK63_RS10295 2224808 2225749 + Virulence factor VirK gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10295 AFK63_RS10300 AFK63_10325 AFK63_RS10300 2226138 2227106 - chemotaxis protein CheV gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10300 AFK63_RS10305 AFK63_10330 AFK63_RS10305 2227665 2227901 + hypothetical protein gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10305 AFK63_RS10310 AFK63_10335 AFK63_RS10310 2228328 2228540 - cold-shock protein gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10310 AFK63_RS10315 AFK63_10340 AFK63_RS10315 2229049 2229705 + hypothetical protein gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10315 AFK63_RS10320 AFK63_10345 AFK63_RS10320 2229773 2230246 - hypothetical protein gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10320 AFK63_RS10325 AFK63_10350 AFK63_RS10325 2231028 2231252 + hypothetical protein gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10325 AFK63_RS10330 AFK63_10355 AFK63_RS10330 2231574 2231903 + hypothetical protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10330 AFK63_RS10335 AFK63_10360 AFK63_RS10335 2232265 2233170 - nucleoside-diphosphate sugar epimerase gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10335 AFK63_RS10340 AFK63_10365 AFK63_RS10340 2233311 2234228 + LysR family transcriptional regulator gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10340 AFK63_RS10345 AFK63_10370 AFK63_RS10345 2234506 2235066 + hypothetical protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10345 AFK63_RS10350 AFK63_10375 AFK63_RS10350 2235599 2235832 - hypothetical protein gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10350 AFK63_RS10355 AFK63_10380 AFK63_RS10355 2235920 2236162 - hypothetical protein gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10355 AFK63_RS10360 AFK63_10385 AFK63_RS10360 2238005 2238751 - membrane protein gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10360 AFK63_RS10365 AFK63_10390 AFK63_RS10365 2239011 2240117 - DNA polymerase V subunit UmuC binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10365 AFK63_RS10370 AFK63_10395 AFK63_RS10370 2240406 2240732 - ferredoxin gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10370 AFK63_RS10375 AFK63_10400 AFK63_RS10375 2241027 2241257 - hypothetical protein gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10375 AFK63_RS10380 AFK63_10405 AFK63_RS10380 2241549 2243369 + copper oxidase gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10380 AFK63_RS10385 AFK63_10410 AFK63_RS10385 2243404 2244339 + copper resistance protein CopB gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10385 AFK63_RS10390 AFK63_10415 AFK63_RS10390 2244369 2244755 + copper resistance protein CopC gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10390 AFK63_RS10395 AFK63_10420 AFK63_RS10395 2244760 2245692 + copper resistance protein CopD gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10395 AFK63_RS10400 AFK63_10425 AFK63_RS10400 2245721 2246401 + two-component system response regulator gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10400 AFK63_RS10405 AFK63_10430 AFK63_RS10405 2246398 2247795 + two-component system sensor histidine kinase gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10405 AFK63_RS10410 AFK63_10435 AFK63_RS10410 2247940 2248290 + hypothetical protein gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10410 AFK63_RS10415 AFK63_10440 AFK63_RS10415 2248521 2249087 - integrase gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10415 AFK63_RS10420 AFK63_10445 AFK63_RS10420 2249178 2250026 - hypothetical protein gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10420 AFK63_RS10425 AFK63_RS10425 AFK63_RS10425 2250093 2250275 + hypothetical protein gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10425 AFK63_RS10430 AFK63_10450 AFK63_RS10430 2250312 2250542 - hypothetical protein gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10430 AFK63_RS10435 AFK63_10455 AFK63_RS10435 2250526 2250963 - DNA polymerase V subunit UmuD binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10435 AFK63_RS10440 AFK63_10460 AFK63_RS10440 2251105 2252154 - hypothetical protein phage-associated protein gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10440 AFK63_RS10445 AFK63_10465 AFK63_RS10445 2253085 2253837 - phage tail protein gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10445 AFK63_RS10450 AFK63_10470 AFK63_RS10450 2253890 2254423 - hypothetical protein gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10450 AFK63_RS10455 AFK63_10475 AFK63_RS10455 2254537 2254827 - hypothetical protein gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10455 AFK63_RS10460 AFK63_10480 AFK63_RS10460 2254827 2258081 - host specificity protein gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10460 AFK63_RS10465 AFK63_10485 AFK63_RS10465 2258131 2258727 - phage tail assembly protein gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10465 AFK63_RS10470 AFK63_10490 AFK63_RS10470 2258724 2259428 - peptidase P60 gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10470 AFK63_RS10475 AFK63_10495 AFK63_RS10475 2259431 2260183 - phage tail protein gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10475 AFK63_RS10480 AFK63_10500 AFK63_RS10480 2260190 2260528 - phage tail protein gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10480 AFK63_RS10485 AFK63_10505 AFK63_RS10485 2260575 2262932 - tail length tape measure protein gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10485 AFK63_RS10490 AFK63_10510 AFK63_RS10490 2263507 2263989 - phage tail assembly protein gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10490 AFK63_RS10495 AFK63_10515 AFK63_RS10495 2264038 2264541 - phage tail fibers gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10495 AFK63_RS10500 AFK63_10520 AFK63_RS10500 2264590 2264955 - hypothetical protein gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10500 AFK63_RS10505 AFK63_10525 AFK63_RS10505 2264952 2265437 - hypothetical protein gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10505 AFK63_RS10510 AFK63_10530 AFK63_RS10510 2265430 2265762 - head-tail adaptor protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10510 AFK63_RS10515 AFK63_10535 AFK63_RS10515 2265765 2265971 - hypothetical protein gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10515 AFK63_RS10520 AFK63_10540 AFK63_RS10520 2266043 2266369 - DNA-packaging protein gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10520 AFK63_RS10525 AFK63_10545 AFK63_RS10525 2266366 2267583 - phage portal protein gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10525 AFK63_RS10530 AFK63_10550 AFK63_RS10530 2267580 2268929 - phage portal protein gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10530 AFK63_RS10535 AFK63_10555 AFK63_RS10535 2269134 2271074 - phage capsid protein gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10535 AFK63_RS10540 AFK63_10560 AFK63_RS10540 2271133 2272791 - terminase gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10540 AFK63_RS10545 AFK63_10565 AFK63_RS10545 2272795 2273292 - phage terminase small subunit gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10545 AFK63_RS10550 AFK63_10570 AFK63_RS10550 2273398 2273766 - HNH nuclease gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10550 AFK63_RS10555 AFK63_10575 AFK63_RS10555 2273759 2274352 - hypothetical protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10555 AFK63_RS10560 AFK63_10580 AFK63_RS10560 2274334 2275791 - glycosyltransferase gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10560 AFK63_RS10565 AFK63_10585 AFK63_RS10565 2275959 2276447 - hypothetical protein gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10565 AFK63_RS10570 AFK63_10590 AFK63_RS10570 2276550 2276978 - hypothetical protein gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10570 AFK63_RS10575 AFK63_10595 AFK63_RS10575 2277002 2277466 - lysozyme gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10575 AFK63_RS10580 AFK63_10600 AFK63_RS10580 2277466 2278089 - endolysin gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10580 AFK63_RS10585 AFK63_10605 AFK63_RS10585 2278086 2278370 - holin gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10585 AFK63_RS10590 AFK63_10610 AFK63_RS10590 2278357 2278737 - membrane protein gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10590 AFK63_RS10595 AFK63_10615 AFK63_RS10595 2278810 2279862 - DNA adenine methylase gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10595 AFK63_RS10600 AFK63_10620 AFK63_RS10600 2280406 2281164 - antitermination protein gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10600 AFK63_RS10605 AFK63_10625 AFK63_RS10605 2281183 2282203 - hypothetical protein gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10605 AFK63_RS10610 AFK63_10630 AFK63_RS10610 2282236 2282961 - antirepressor gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10610 AFK63_RS10615 AFK63_10635 AFK63_RS10615 2282977 2283360 - crossover junction endodeoxyribonuclease gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10615 AFK63_RS10620 AFK63_10640 AFK63_RS10620 2283357 2283638 - LexA family transcriptional regulator gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10620 AFK63_RS10625 AFK63_10645 AFK63_RS10625 2283695 2285677 - DNA methyltransferase gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10625 AFK63_RS10630 AFK63_10650 AFK63_RS10630 2285674 2286537 - DNA adenine methylase gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10630 AFK63_RS10635 AFK63_10655 AFK63_RS10635 2286537 2286773 - hypothetical protein gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10635 AFK63_RS10640 AFK63_10660 AFK63_RS10640 2286770 2287666 - GntR family transcriptional regulator gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10640 AFK63_RS10645 AFK63_10665 AFK63_RS10645 2288024 2288560 - hypothetical protein gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10645 AFK63_RS10650 AFK63_10670 AFK63_RS10650 2288707 2288901 - Cro/Cl family transcriptional regulator gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10650 AFK63_RS10655 AFK63_10675 AFK63_RS10655 2289009 2289725 + peptidase S24 gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10655 AFK63_RS10660 AFK63_10680 AFK63_RS10660 2290259 2290522 + hypothetical protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10660 AFK63_RS10665 AFK63_10685 AFK63_RS10665 2290692 2291636 + hypothetical protein gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10665 AFK63_RS10670 AFK63_10690 AFK63_RS10670 2292352 2292534 + hypothetical protein gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10670 AFK63_RS10675 AFK63_10695 AFK63_RS10675 2292831 2293400 + ATPase gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10675 AFK63_RS10680 AFK63_10700 AFK63_RS10680 2293439 2293684 + excisionase gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10680 AFK63_RS10685 AFK63_10705 AFK63_RS10685 2293665 2294792 + integrase gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10685 AFK63_RS10690 AFK63_10710 AFK63_RS10690 2294910 2296160 - isocitrate dehydrogenase Converts isocitrate to alpha ketoglutarate gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10690 AFK63_RS10695 AFK63_10715 AFK63_RS10695 2296306 2296932 + 23S rRNA pseudouridylate synthase catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10695 AFK63_RS10700 AFK63_10720 AFK63_RS10700 2296943 2297392 + phosphatase gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10700 AFK63_RS10705 AFK63_10725 AFK63_RS10705 2297671 2299620 + chemotaxis protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10705 AFK63_RS10710 AFK63_10730 mnmA mnmA 2299828 2300937 + tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10710 AFK63_RS10715 AFK63_10735 AFK63_RS10715 2300994 2301623 + lysogenization regulator HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10715 AFK63_RS10720 AFK63_10740 AFK63_RS10720 2301641 2303011 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10720 AFK63_RS10725 AFK63_10745 AFK63_RS10725 2303178 2303849 + two-component system response regulator response regulator in two-component regulatory system with PhoQ%3B involved in magnesium starvation and stress gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10725 AFK63_RS10730 AFK63_10750 AFK63_RS10730 2303850 2305352 + sensor protein PhoQ gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10730 AFK63_RS10735 AFK63_10755 AFK63_RS10735 2305402 2306523 + 50S ribosomal protein L16 arginine hydroxylase gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10735 AFK63_RS10740 AFK63_10760 AFK63_RS10740 2306650 2307879 - peptidase T gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10740 AFK63_RS10745 AFK63_10765 AFK63_RS10745 2307953 2308141 - hypothetical protein gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10745 AFK63_RS10750 AFK63_10770 potA potA 2308167 2309315 + putrescine/spermidine ABC transporter ATPase functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport%3B PotA is the membrane-associated ATPase gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10750 AFK63_RS10755 AFK63_10775 potB potB 2309299 2310156 + spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotB is a membrane component gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10755 AFK63_RS10760 AFK63_10780 potC potC 2310153 2310965 + spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotC is a membrane component gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10760 AFK63_RS10765 AFK63_10785 potD potD 2310962 2312008 + spermidine/putrescine ABC transporter substrate-binding protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotD is a periplasmic component that binds the substrate gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10765 AFK63_RS10770 AFK63_10790 AFK63_RS10770 2312116 2312940 - NAD-dependent deacetylase Modulates the activities of several enzymes which are inactive in their acetylated form gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10770 AFK63_RS10775 AFK63_10795 AFK63_RS10775 2312942 2313862 - N-acetylglucosamine kinase catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10775 AFK63_RS10780 AFK63_10800 AFK63_RS10780 2313878 2315122 - outer membrane-specific lipoprotein transporter subunit LolE part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10780 AFK63_RS10785 AFK63_10805 lolD lolD 2315123 2315827 - lipoprotein ABC transporter ATP-binding protein outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10785 AFK63_RS10790 AFK63_10810 AFK63_RS10790 2315820 2317019 - outer membrane-specific lipoprotein transporter subunit LolC part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10790 AFK63_RS10795 AFK63_10815 AFK63_RS10795 2317160 2320606 + transcription-repair coupling factor gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10795 AFK63_RS10800 AFK63_10820 AFK63_RS10800 2320740 2321714 + peptidoglycan-binding protein LysM gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10800 AFK63_RS10805 AFK63_10825 AFK63_RS10805 2321775 2322032 - multiple stress resistance protein BhsA gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10805 AFK63_RS10810 AFK63_10830 AFK63_RS10810 2322284 2322916 + TetR family transcriptional regulator gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10810 AFK63_RS10815 AFK63_10835 AFK63_RS10815 2323550 2324089 - hypothetical protein gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10815 AFK63_RS10820 AFK63_10840 AFK63_RS10820 2324276 2325580 - NADH dehydrogenase gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10820 AFK63_RS10825 AFK63_10845 AFK63_RS10825 2325815 2326357 - hypothetical protein gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10825 AFK63_RS10830 AFK63_10850 AFK63_RS10830 2326397 2327419 - beta-hexosaminidase hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10830 AFK63_RS10835 AFK63_10855 thiK thiK 2327407 2328255 - thiamine kinase catalyzes the phosphorylation of thiamine to thiamine phosphate gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10835 AFK63_RS10840 AFK63_10860 AFK63_RS10840 2328233 2328886 - penicillin-binding protein gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10840 AFK63_RS10845 AFK63_10865 AFK63_RS10845 2328907 2329281 - membrane protein gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10845 AFK63_RS10850 AFK63_10870 AFK63_RS10850 2329283 2329642 - purine nucleoside phosphoramidase gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10850 AFK63_RS10855 AFK63_10875 AFK63_RS10855 2329990 2332191 + ferric-rhodotorulic acid transporter gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10855 AFK63_RS10860 AFK63_10880 AFK63_RS10860 2332425 2333858 - PTS glucose subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10860 AFK63_RS10865 AFK63_10885 AFK63_RS10865 2334157 2334951 - DNAse gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10865 AFK63_RS10870 AFK63_10890 AFK63_RS10870 2334962 2335969 - DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10870 AFK63_RS10875 AFK63_10895 AFK63_RS10875 2335969 2336607 - thymidylate kinase gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10875 AFK63_RS10880 AFK63_10900 AFK63_RS10880 2336597 2337619 - aminodeoxychorismate lyase gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10880 AFK63_RS10885 AFK63_10905 AFK63_RS10885 2337630 2338430 - 4-amino-4-deoxychorismate lyase catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10885 AFK63_RS10890 AFK63_10910 AFK63_RS10890 2338539 2339780 - 3-oxoacyl-ACP synthase FabF%3B beta-ketoacyl-ACP synthase II%2C KASII%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10890 AFK63_RS10895 AFK63_10915 AFK63_RS10895 2339873 2340109 - acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10895 AFK63_RS10900 AFK63_10920 fabG fabG 2340264 2340998 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10900 AFK63_RS10905 AFK63_10925 AFK63_RS10905 2341012 2341941 - malonyl CoA-ACP transacylase gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10905 AFK63_RS10910 AFK63_10930 AFK63_RS10910 2341959 2342912 - 3-oxoacyl-ACP synthase FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10910 AFK63_RS10915 AFK63_10935 AFK63_RS10915 2342919 2343923 - phosphate acyltransferase gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10915 AFK63_RS10920 AFK63_10940 rpmF rpmF 2344026 2344199 - 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10920 AFK63_RS10925 AFK63_10945 AFK63_RS10925 2344251 2344772 - hypothetical protein gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10925 AFK63_RS10930 AFK63_10950 AFK63_RS10930 2344913 2345500 + septum formation inhibitor Maf gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10930 AFK63_RS10935 AFK63_10955 AFK63_RS10935 2345557 2346273 - hypothetical protein gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10935 AFK63_RS10940 AFK63_10960 AFK63_RS10940 2346397 2347350 - 23S rRNA pseudouridylate synthase catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10940 AFK63_RS10945 AFK63_10965 rne rne 2347918 2351115 + ribonuclease E bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein%3B forms part of the membrane-associated degradosome complex along with PNPase%2C RhlB%2C and enolase gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10945 AFK63_RS10950 AFK63_10970 AFK63_RS10950 2351182 2352120 - LysR family transcriptional regulator gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10950 AFK63_RS10955 AFK63_10975 AFK63_RS10955 2352237 2353472 + MFS transporter gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10955 AFK63_RS10960 AFK63_10980 flgL flgL 2353555 2354517 - flagellar hook protein FlgL with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10960 AFK63_RS10965 AFK63_10985 flgK flgK 2354532 2356190 - flagellar hook protein FlgK with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10965 AFK63_RS10970 AFK63_10990 flgJ flgJ 2356266 2357231 - flagellar rod assembly protein FlgJ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10970 AFK63_RS10975 AFK63_10995 flgI flgI 2357231 2358328 - flagellar basal body P-ring biosynthesis protein FlgA part of the basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod%3B Vibrio parahaemolyticus%2C Yersinia%2C Bradyrhizobium and other bacteria have two copies of this and other flagellar genes%3B the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10975 AFK63_RS10980 AFK63_11000 flgH flgH 2358341 2359039 - flagellar basal body L-ring protein part of the flagellar basal body which consists of four rings L%2CP%2C S and M mounted on a central rod gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10980 AFK63_RS10985 AFK63_11005 flgG flgG 2359097 2359879 - flagellar basal body rod protein FlgG makes up the distal portion of the flagellar basal body rod gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10985 AFK63_RS10990 AFK63_11010 flgF flgF 2359896 2360654 - flagellar basal body rod protein FlgF FlgF%2C with FlgB and C%2C makes up the proximal portion of the flagellar basal body rod gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10990 AFK63_RS10995 AFK63_11015 flgE flgE 2360675 2361907 - flagellar hook protein FlgE the hook connects flagellar basal body to the flagellar filament gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS10995 AFK63_RS11000 AFK63_11020 flgD flgD 2361934 2362614 - flagellar basal body rod modification protein acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of some flagellar genes%3B in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11000 AFK63_RS11005 AFK63_11025 flgC flgC 2362626 2363030 - flagellar basal body rod protein FlgC with FlgF and B makes up the proximal portion of the flagellar basal body rod gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11005 AFK63_RS11010 AFK63_11030 AFK63_RS11010 2363044 2363457 - flagellar biosynthesis protein FlgB gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11010 AFK63_RS11015 AFK63_11035 AFK63_RS11015 2363611 2364270 + flagellar basal body P-ring biosynthesis protein FlgA gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11015 AFK63_RS11020 AFK63_11040 AFK63_RS11020 2364367 2364660 + Negative regulator of flagellin synthesis gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11020 AFK63_RS11025 AFK63_11045 AFK63_RS11025 2364664 2365089 + flagellar biosynthesis protein FlgN export chaperone for FlgK and FlgL gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11025 AFK63_RS11030 AFK63_11050 AFK63_RS11030 2365231 2366766 - membrane protein gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11030 AFK63_RS11035 AFK63_11055 AFK63_RS11035 2366882 2367805 - virulence factor MviM gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11035 AFK63_RS11040 AFK63_11060 AFK63_RS11040 2367808 2368461 - hypothetical protein gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11040 AFK63_RS11045 AFK63_11065 AFK63_RS11045 2368472 2369056 - ribosomal-protein-alanine acetyltransferase gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11045 AFK63_RS11050 AFK63_11070 AFK63_RS11050 2369322 2370530 + multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11050 AFK63_RS11055 AFK63_11075 AFK63_RS11055 2370607 2371254 + glutaredoxin gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11055 AFK63_RS11060 AFK63_11080 AFK63_RS11060 2371373 2371933 + lipoprotein gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11060 AFK63_RS11065 AFK63_11085 AFK63_RS11065 2372061 2373107 + dihydroorotase gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11065 AFK63_RS11070 AFK63_11090 AFK63_RS11070 2373192 2373437 + damage-inducible protein I gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11070 AFK63_RS11075 AFK63_11095 bssS bssS 2373762 2374013 + hypothetical protein BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11075 AFK63_RS11080 AFK63_11100 solA solA 2374131 2375255 + N-methyltryptophan oxidase catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde%3B FAD-binding%3B can also catalyze the demethylation of other N-methyl amino acids gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11080 AFK63_RS11085 AFK63_11105 AFK63_RS11085 2375580 2376134 + cytochrome B561 gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11085 AFK63_RS11090 AFK63_11110 AFK63_RS11090 2376149 2376724 + hypothetical protein gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11090 AFK63_RS11095 AFK63_11115 AFK63_RS11095 2376780 2377829 - sulfurtransferase gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11095 AFK63_RS11100 AFK63_11120 AFK63_RS11100 2378052 2378972 + lipid A biosynthesis lauroyl acyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11100 AFK63_RS11105 AFK63_11125 AFK63_RS11105 2379102 2379479 + secY/secA suppressor protein gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11105 AFK63_RS11110 AFK63_11130 AFK63_RS11110 2379483 2379710 - lipoprotein gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11110 AFK63_RS11115 AFK63_11135 AFK63_RS11115 2379818 2382346 - glucosyltransferase MdoH necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11115 AFK63_RS11120 AFK63_11140 mdoG mdoG 2382339 2383892 - glucan biosynthesis protein G involved in the biosynthesis of osmoregulated periplasmic glucans%3B required for the assembly of the polyglucose structure of glucan gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11120 AFK63_RS11125 AFK63_11145 opgC opgC 2384148 2385305 + glucan biosynthesis protein required for the transfer of succinyl residues to osmoregulated periplasmic glucans gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11125 AFK63_RS11130 AFK63_11150 AFK63_RS11130 2385355 2386842 - hypothetical protein gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11130 AFK63_RS11135 AFK63_11155 AFK63_RS11135 2386775 2387317 - RNase III inhibitor interacts and inactivates RNase III during cold shock gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11135 AFK63_RS11140 AFK63_11160 AFK63_RS11140 2387386 2387688 - hypothetical protein gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11140 AFK63_RS11145 AFK63_11165 AFK63_RS11145 2387865 2388338 - membrane protein gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11145 AFK63_RS11150 AFK63_11170 AFK63_RS11150 2388449 2389015 - molecular chaperone gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11150 AFK63_RS11155 AFK63_11175 AFK63_RS11155 2389040 2389777 - hydrolase gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11155 AFK63_RS11160 AFK63_11180 ghrA ghrA 2389862 2390803 - bifunctional glyoxylate/hydroxypyruvate reductase A catalyzes the formation of glycolate and glycerate from glyoxylate and hydroxypyruvate%2C respectively gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11160 AFK63_RS11165 AFK63_11185 AFK63_RS11165 2390886 2391914 - fimbrial protein gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11165 AFK63_RS11170 AFK63_11190 AFK63_RS11170 2391930 2394413 - hypothetical protein gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11170 AFK63_RS11175 AFK63_11195 AFK63_RS11175 2394500 2395189 - pilus assembly protein gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11175 AFK63_RS11180 AFK63_11200 AFK63_RS11180 2395268 2395801 - fimbrial protein gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11180 AFK63_RS11185 AFK63_11205 AFK63_RS11185 2396361 2396448 + tRNA-Ser tRNA gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11185 AFK63_RS11190 AFK63_11210 AFK63_RS11190 2396958 2399282 - hypothetical protein gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11190 AFK63_RS11195 AFK63_11215 AFK63_RS11195 2399529 2399616 + tRNA-Ser tRNA gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11195 AFK63_RS11200 AFK63_11220 AFK63_RS11200 2400301 2401002 - hypothetical protein gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11200 AFK63_RS11205 AFK63_11225 AFK63_RS11205 2401174 2401962 - hypothetical protein gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11205 AFK63_RS11210 AFK63_11230 AFK63_RS11210 2402506 2403789 - peroxidase gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11210 AFK63_RS11215 AFK63_11235 AFK63_RS11215 2403795 2404922 - ferrous iron transporter with EfeUB forms an iron transport system which is silent in E. coli K-12 due to a mutation in EfeU gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11215 AFK63_RS11220 AFK63_11240 AFK63_RS11220 2404978 2405808 - iron permease gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11220 AFK63_RS11225 AFK63_11245 AFK63_RS11225 2406176 2407360 + nucleoside permease gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11225 AFK63_RS11230 AFK63_11250 AFK63_RS11230 2407438 2407866 - hypothetical protein gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11230 AFK63_RS11235 AFK63_11255 AFK63_RS11235 2407984 2409492 - proline:sodium symporter PutP involved in the sodium dependent uptake of proline gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11235 AFK63_RS11240 AFK63_11260 putA putA 2409906 2413868 + transcriptional regulator proline utilization protein A%3B multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate%3B in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus%3B forms dimers and is a peripherally membrane-associated protein gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11240 AFK63_RS11245 AFK63_11265 AFK63_RS11245 2413928 2414566 - transcriptional regulator gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11245 AFK63_RS11250 AFK63_11270 AFK63_RS11250 2414858 2415946 + pyrimidine monooxygenase gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11250 AFK63_RS11255 AFK63_11275 AFK63_RS11255 2415946 2416644 + amidohydrolase gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11255 AFK63_RS11260 AFK63_11280 AFK63_RS11260 2416654 2417052 + ring-opening amidohydrolase RutC in novel pyrimidine catabolism pathway gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11260 AFK63_RS11265 AFK63_11285 AFK63_RS11265 2417052 2417855 + aminoacrylate hydrolase gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11265 AFK63_RS11270 AFK63_11290 AFK63_RS11270 2417852 2418442 + malonic semialdehyde reductase gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11270 AFK63_RS11275 AFK63_11295 AFK63_RS11275 2418452 2418952 + FMN reductase gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11275 AFK63_RS11280 AFK63_11300 AFK63_RS11280 2418970 2420304 + pyrimidine permease gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11280 AFK63_RS11285 AFK63_11305 AFK63_RS11285 2420371 2420553 - hypothetical protein gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11285 AFK63_RS11290 AFK63_11310 AFK63_RS11290 2420967 2421563 + NAD(P)H:quinone oxidoreductase catalyzes the transfer of electrons from NADH to ubiquinone gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11290 AFK63_RS11295 AFK63_11315 AFK63_RS11295 2421585 2421812 + hypothetical protein gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11295 AFK63_RS11300 AFK63_11320 AFK63_RS11300 2421883 2423580 - arylsulfotransferase gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11300 AFK63_RS11305 AFK63_11325 AFK63_RS11305 2424047 2424835 + membrane protein gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11305 AFK63_RS11310 AFK63_11330 AFK63_RS11310 2424855 2426363 + arylsulfatase gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11310 AFK63_RS11315 AFK63_11335 AFK63_RS11315 2426472 2427647 + anaerobic sulfatase maturase gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11315 AFK63_RS11320 AFK63_11340 AFK63_RS11320 2427632 2428930 + cytoplasmic protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11320 AFK63_RS11325 AFK63_11345 AFK63_RS11325 2429074 2430408 - type VI secretion protein gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11325 AFK63_RS11330 AFK63_11350 AFK63_RS11330 2430432 2430887 - type VI secretion system lysozyme-like protein gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11330 AFK63_RS11335 AFK63_11355 AFK63_RS11335 2430909 2432487 - type VI secretion protein gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11335 AFK63_RS11340 AFK63_11360 AFK63_RS11340 2432800 2432887 - tRNA-Ser tRNA gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11340 AFK63_RS11345 AFK63_11365 AFK63_RS11345 2433045 2434670 - peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11345 AFK63_RS11350 AFK63_11370 AFK63_RS11350 2434930 2435589 + TEGT family carrier/transporter binds to the HflBKC complex which modulates FtsH activity gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11350 AFK63_RS11355 AFK63_11375 AFK63_RS11355 2435697 2436026 + sulfur transfer protein TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11355 AFK63_RS11360 AFK63_11380 AFK63_RS11360 2436023 2436304 - acylphosphatase gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11360 AFK63_RS11365 AFK63_11385 AFK63_RS11365 2436393 2437583 + 23S rRNA methyltransferase SAM-dependent%3Bcatalyzes the methylation of cytosine at position 1962 of the 23S rRNA gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11365 AFK63_RS11370 AFK63_11390 AFK63_RS11370 2437643 2437960 + heat-shock protein HspQ gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11370 AFK63_RS11375 AFK63_11395 AFK63_RS11375 2437988 2438401 - succinyl-CoA synthetase subunit alpha-related enzymes gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11375 AFK63_RS11380 AFK63_11400 AFK63_RS11380 2438575 2439033 + methylglyoxal synthase gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11380 AFK63_RS11385 AFK63_11405 helD helD 2439034 2441088 - DNA helicase IV catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11385 AFK63_RS11390 AFK63_11410 AFK63_RS11390 2441215 2441661 + hypothetical protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11390 AFK63_RS11395 AFK63_11415 AFK63_RS11395 2441675 2443810 + membrane protein gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11395 AFK63_RS11400 AFK63_11420 AFK63_RS11400 2443801 2444415 - competence protein gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11400 AFK63_RS11405 AFK63_11425 AFK63_RS11405 2444633 2445139 + cell division protein gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11405 AFK63_RS11410 AFK63_11430 AFK63_RS11410 2445465 2446541 + membrane protein OmpA is believed to be a porin%2C involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli%2C and it is known to play a role as a phage receptor%2C a mediator of F-factor dependent conjugation%2C and in maintaining the structural shape of the outer membrane%3B 3a%3B II*%3B G%3B d gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11410 AFK63_RS11415 AFK63_11435 AFK63_RS11415 2446764 2447219 - macrodomain Ter protein gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11415 AFK63_RS11420 AFK63_11440 AFK63_RS11420 2447403 2449160 + lon protease gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11420 AFK63_RS11425 AFK63_11445 AFK63_RS11425 2449229 2449747 + 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11425 AFK63_RS11430 AFK63_11450 AFK63_RS11430 2450243 2450806 - lipoprotein gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11430 AFK63_RS11435 AFK63_11455 AFK63_RS11435 2450803 2452443 - paraquat-inducible protein B gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11435 AFK63_RS11440 AFK63_11460 AFK63_RS11440 2452433 2453701 - paraquat-inducible membrane protein A gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11440 AFK63_RS11445 AFK63_11465 AFK63_RS11445 2453718 2455622 - ABC transporter ATPase Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11445 AFK63_RS11450 AFK63_11470 rlmL rlmL 2455629 2457746 - 23S rRNA methyltransferase catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11450 AFK63_RS11455 AFK63_11475 AFK63_RS11455 2457849 2458955 + hypothetical protein gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11455 AFK63_RS11460 AFK63_11480 AFK63_RS11460 2458952 2459494 - cell division protein ZapC gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11460 AFK63_RS11465 AFK63_11485 AFK63_RS11465 2459660 2460670 - dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11465 AFK63_RS11470 AFK63_11490 AFK63_RS11470 2460919 2461494 + FMN reductase gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11470 AFK63_RS11475 AFK63_11495 AFK63_RS11475 2461487 2462458 + alkanesulfonate transporter substrate-binding subunit part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11475 AFK63_RS11480 AFK63_11500 AFK63_RS11480 2462455 2463600 + alkanesulfonate monooxygenase catalyzes the release of sulfite from alkanesulfonates gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11480 AFK63_RS11485 AFK63_11505 ssuC ssuC 2463610 2464401 + alkanesulfonate transporter permease subunit part of the ABC type transport system for alkanesulfonate SsuABC%3B SsuB the ATP-binding subunit and SsuC the permease gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11485 AFK63_RS11490 AFK63_11510 ssuB ssuB 2464398 2465165 + aliphatic sulfonate ABC transporter ATP-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic substrate-binding subunit%2C SsuB the ATP-binding subunit and SsuC the permease gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11490 AFK63_RS11495 AFK63_11515 pepN pepN 2465322 2467934 - aminopeptidase N gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11495 AFK63_RS11500 AFK63_11520 AFK63_RS11500 2468201 2469403 + nicotinate phosphoribosyltransferase catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11500 AFK63_RS11505 AFK63_11525 AFK63_RS11505 2469570 2470970 + asparaginyl-tRNA synthetase gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11505 AFK63_RS11510 AFK63_11530 AFK63_RS11510 2471503 2472666 + porin gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11510 AFK63_RS11515 AFK63_11535 AFK63_RS11515 2472852 2474042 + aromatic amino acid aminotransferase gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11515 AFK63_RS11520 AFK63_11540 AFK63_RS11520 2474098 2474745 - hypothetical protein gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11520 AFK63_RS11525 AFK63_11545 AFK63_RS11525 2474784 2475332 - hypothetical protein gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11525 AFK63_RS11530 AFK63_11550 AFK63_RS11530 2475513 2477318 - murein transpeptidase catalyzes the formation of a meso-diaminopimelyl- meso-diaminopimelyl crosslink gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11530 AFK63_RS11535 AFK63_11555 mukB mukB 2477473 2481921 - cell division protein MukB SMC (structural maintenance of chromosomes) family of proteins%3B involved in chromosome condensatin and partitioning%3B forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ%3B mutations result in cell division defects gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11535 AFK63_RS11540 AFK63_11560 AFK63_RS11540 2481914 2482624 - condesin subunit E acts with MukB and MukF to condense the chromosome and allow for segregation during cell division gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11540 AFK63_RS11545 AFK63_11565 AFK63_RS11545 2482605 2483927 - condesin subunit F acts with MukB and MukE to condense the chromosome and allow for segregation during cell division gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11545 AFK63_RS11550 AFK63_11570 AFK63_RS11550 2483931 2484710 - SAM-dependent methyltransferase gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11550 AFK63_RS11555 AFK63_11575 AFK63_RS11555 2484843 2485622 + hypothetical protein gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11555 AFK63_RS11560 AFK63_11580 AFK63_RS11560 2485599 2486492 - hypothetical protein gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11560 AFK63_RS11565 AFK63_11585 AFK63_RS11565 2486585 2487007 - hypothetical protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11565 AFK63_RS11570 AFK63_11590 AFK63_RS11570 2487134 2487619 + AsnC family transcriptional regulator gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11570 AFK63_RS11575 AFK63_11595 AFK63_RS11575 2487644 2488390 - 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11575 AFK63_RS11580 AFK63_11600 AFK63_RS11580 2488387 2488569 - hypothetical protein gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11580 AFK63_RS11585 AFK63_11605 AFK63_RS11585 2488595 2489854 - hypothetical protein gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11585 AFK63_RS11590 AFK63_11610 lpxK lpxK 2489892 2490869 - tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11590 AFK63_RS11595 AFK63_11615 AFK63_RS11595 2490866 2492614 - lipid transporter ATP-binding/permease involved in the transport of lipid A across the inner membrane gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11595 AFK63_RS11600 AFK63_11620 AFK63_RS11600 2492651 2494876 - competence protein ComEC gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11600 AFK63_RS11605 AFK63_11625 ihfB ihfB 2495113 2495397 - integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11605 AFK63_RS11610 AFK63_11630 rpsA rpsA 2495512 2497185 - 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11610 AFK63_RS11615 AFK63_11635 cmk cmk 2497297 2497983 - cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11615 AFK63_RS11620 AFK63_11640 AFK63_RS11620 2498158 2498925 - metalloprotease gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11620 AFK63_RS11625 AFK63_11645 AFK63_RS11625 2499072 2500358 - 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11625 AFK63_RS11630 AFK63_11650 AFK63_RS11630 2500427 2501512 - 3-phosphoserine/phosphohydroxythreonine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11630 AFK63_RS11635 AFK63_11655 AFK63_RS11635 2501675 2502367 - membrane protein gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11635 AFK63_RS11640 AFK63_11660 AFK63_RS11640 2502509 2504272 + ribosomal protein S12 methylthiotransferase accessory factor YcaO gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11640 AFK63_RS11645 AFK63_11665 AFK63_RS11645 2504675 2505532 + formate transporter FocA gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11645 AFK63_RS11650 AFK63_11670 AFK63_RS11650 2505584 2507866 + pyruvate formate-lyase formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11650 AFK63_RS11655 AFK63_11675 pflA pflA 2508062 2508802 + pyruvate formate-lyase activating enzyme activates pyruvate formate-lyase 1 under anaerobic conditions gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11655 AFK63_RS11660 AFK63_11680 AFK63_RS11660 2508852 2510000 - MFS transporter gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11660 AFK63_RS11665 AFK63_11685 AFK63_RS11665 2510296 2511588 - seryl-tRNA synthetase gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11665 AFK63_RS11670 AFK63_11690 AFK63_RS11670 2511686 2513029 - recombination factor protein RarA gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11670 AFK63_RS11675 AFK63_11695 lolA lolA 2513038 2513652 - outer membrane lipoprotein carrier protein LolA participates with LolB in the incorporation of lipoprotein into the outer membrane gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11675 AFK63_RS11680 AFK63_11700 AFK63_RS11680 2513840 2518018 - cell division protein FtsK DNA-binding membrane protein required for chromosome resolution and partitioning gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11680 AFK63_RS11685 AFK63_11705 AFK63_RS11685 2518138 2518632 - leucine-responsive regulatory protein mediates a global response to leucine%3B acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11685 AFK63_RS11690 AFK63_11710 AFK63_RS11690 2519102 2520070 + thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11690 AFK63_RS11695 AFK63_11715 AFK63_RS11695 2520186 2521952 + amino acid ABC transporter permease in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11695 AFK63_RS11700 AFK63_11720 AFK63_RS11700 2521953 2523686 + amino acid ABC transporter permease in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11700 AFK63_RS11705 AFK63_11725 aat aat 2523724 2524428 + leucyl/phenylalanyl-tRNA--protein transferase leucyltransferase%3B phenylalanyltransferse%3B functions in the N-end rule pathway%3B transfers Leu%2C Phe%2C Met%2C from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11705 AFK63_RS11710 AFK63_11730 AFK63_RS11710 2524704 2524922 + translation initiation factor IF-1 gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11710 AFK63_RS11715 AFK63_11735 clpA clpA 2525102 2527375 - ATP-dependent Clp protease ATP-binding subunit ClpA ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease%3B directs protease to specific substrates gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11715 AFK63_RS11720 AFK63_11740 clpS clpS 2527404 2527724 - Clp protease ClpS involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B binds to the N-terminal domain of the chaperone ClpA gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11720 AFK63_RS11725 AFK63_11745 AFK63_RS11725 2528050 2528280 + cold-shock protein inhibits DNA replication at both initiation and elongation steps%3B stationary phase and starvation inducible gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11725 AFK63_RS11730 AFK63_11750 AFK63_RS11730 2528345 2530288 - MacB family efflux pump subunit with MacA is involved in the export of macrolide gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11730 AFK63_RS11735 AFK63_11755 AFK63_RS11735 2530285 2531397 - macrolide transporter confers macrolide resistance via active drug efflux gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11735 AFK63_RS11740 AFK63_11760 AFK63_RS11740 2531562 2532530 + hypothetical protein gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11740 AFK63_RS11745 AFK63_11765 AFK63_RS11745 2532620 2534278 - hypothetical protein gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11745 AFK63_RS11750 AFK63_11770 AFK63_RS11750 2534547 2535446 + membrane protein gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11750 AFK63_RS11755 AFK63_11775 AFK63_RS11755 2535587 2537239 + hydroxylamine reductase gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11755 AFK63_RS11760 AFK63_11780 AFK63_RS11760 2537249 2538217 + oxidoreductase gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11760 AFK63_RS11765 AFK63_11785 AFK63_RS11765 2538337 2538771 - GntR family transcriptional regulator gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11765 AFK63_RS11770 AFK63_11790 AFK63_RS11770 2538924 2540642 + pyruvate dehydrogenase catalyzes the formation of acetate from pyruvate gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11770 AFK63_RS11775 AFK63_11795 AFK63_RS11775 2540677 2541684 + threonine aldolase low- specificity%3B catalyzes the formation of acetaldehyde and glycine from L-threonine%3B acts on L-threonine%2C L-allo-threonine%2C L-threo-phenylserine%2C and L-erythro-phenylserine gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11775 AFK63_RS11780 AFK63_11800 AFK63_RS11780 2541814 2542830 + hypothetical protein gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11780 AFK63_RS11785 AFK63_11805 AFK63_RS11785 2542878 2543708 - N-acetylmuramoyl-L-alanine amidase catalyzes the cleavage of the bond between muamic acid and l-alanine gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11785 AFK63_RS11790 AFK63_11810 AFK63_RS11790 2543705 2544028 - hypothetical protein gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11790 AFK63_RS11795 AFK63_11815 AFK63_RS11795 2544156 2544683 + lipoprotein induced during stationary phase and by acivicin (a glutamine analog)%3B regulated by Lrp and RpoS gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11795 AFK63_RS11800 AFK63_11820 AFK63_RS11800 2544885 2545613 + arginine ABC transporter ATP-binding protein gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11800 AFK63_RS11805 AFK63_11825 AFK63_RS11805 2545634 2546365 + arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11805 AFK63_RS11810 AFK63_11830 AFK63_RS11810 2546374 2547090 + arginine transporter permease subunit ArtQ with ArtPMJI transports arginine across the inner membrane gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11810 AFK63_RS11815 AFK63_11835 artM artM 2547090 2547758 + arginine transporter permease subunit ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11815 AFK63_RS11820 AFK63_11840 AFK63_RS11820 2548021 2548752 + arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11820 AFK63_RS11825 AFK63_11845 AFK63_RS11825 2548791 2549642 - AraC family transcriptional regulator gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11825 AFK63_RS11830 AFK63_11850 AFK63_RS11830 2549834 2551678 + hypothetical protein gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11830 AFK63_RS11835 AFK63_11855 AFK63_RS11835 2551696 2552955 + MFS sugar transporter gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11835 AFK63_RS11840 AFK63_11860 AFK63_RS11840 2552984 2554171 + glucuronyl hydrolase gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11840 AFK63_RS11845 AFK63_11865 rumB rumB 2554221 2555348 - 23S rRNA methyltransferase RNA uridine methyltransferase B%3B catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11845 AFK63_RS11850 AFK63_11870 AFK63_RS11850 2555400 2555834 - hypothetical protein gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11850 AFK63_RS11855 AFK63_11875 AFK63_RS11855 2555948 2556793 - spermidine/putrescine ABC transporter permease gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11855 AFK63_RS11860 AFK63_11880 AFK63_RS11860 2556790 2557749 - spermidine/putrescine ABC transporter permease gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11860 AFK63_RS11865 AFK63_11885 potG potG 2557761 2558912 - putrescine transporter ATP-binding subunit part of the PotFGHI ATP-dependent putrescine transporter gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11865 AFK63_RS11870 AFK63_11890 AFK63_RS11870 2559034 2560146 - spermidine/putrescine ABC transporter substrate-binding protein gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11870 AFK63_RS11875 AFK63_11895 AFK63_RS11875 2560506 2560985 - hypothetical protein gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11875 AFK63_RS11880 AFK63_11900 AFK63_RS11880 2561068 2561970 - ribosomal protein S6 modification protein responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11880 AFK63_RS11885 AFK63_11905 AFK63_RS11885 2562048 2562770 - nitroreductase A NADPH-dependent%3B oxygen-insensitive%3B catalyzes the reduction of nitroaromatic compounds gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11885 AFK63_RS11890 AFK63_11910 AFK63_RS11890 2562903 2563280 - membrane protein gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11890 AFK63_RS11895 AFK63_11915 AFK63_RS11895 2563571 2565253 + transporter gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11895 AFK63_RS11900 AFK63_11920 AFK63_RS11900 2565928 2566242 - hypothetical protein gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11900 AFK63_RS11905 AFK63_11925 AFK63_RS11905 2566245 2566700 - membrane protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11905 AFK63_RS11910 AFK63_11930 AFK63_RS11910 2567219 2567455 + hypothetical protein gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11910 AFK63_RS11915 AFK63_11935 AFK63_RS11915 2567452 2567997 - DeoR family transcriptional regulator gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11915 AFK63_RS11920 AFK63_11940 AFK63_RS11920 2568105 2569319 + membrane protein gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11920 AFK63_RS11925 AFK63_11945 AFK63_RS11925 2569312 2570760 - flagellin gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11925 AFK63_RS11930 AFK63_11950 AFK63_RS11930 2570941 2571753 + sugar phosphatase gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11930 AFK63_RS11935 AFK63_11955 AFK63_RS11935 2571787 2573019 - multidrug transporter gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11935 AFK63_RS11940 AFK63_11960 AFK63_RS11940 2573186 2573926 + phosphoesterase gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11940 AFK63_RS11945 AFK63_11965 AFK63_RS11945 2573923 2574516 + UDP pyrophosphate phosphatase gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11945 AFK63_RS11950 AFK63_11970 AFK63_RS11950 2574596 2575360 + DeoR family transcriptional regulator gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11950 AFK63_RS11955 AFK63_11975 AFK63_RS11955 2575388 2576599 - peptidase M15 gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11955 AFK63_RS11960 AFK63_11980 AFK63_RS11960 2576864 2577490 + glutathione S-transferase gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11960 AFK63_RS11965 AFK63_11985 AFK63_RS11965 2577491 2578603 - oxidoreductase gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11965 AFK63_RS11970 AFK63_11990 AFK63_RS11970 2579831 2580631 - hypothetical protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11970 AFK63_RS11975 AFK63_11995 AFK63_RS11975 2580762 2581337 - hypothetical protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11975 AFK63_RS11980 AFK63_12000 AFK63_RS11980 2581839 2583023 + hypothetical protein gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11980 AFK63_RS11985 AFK63_12005 AFK63_RS11985 2583496 2585247 + hypothetical protein gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11985 AFK63_RS11990 AFK63_12010 AFK63_RS11990 2585630 2585983 - hypothetical protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11990 AFK63_RS11995 AFK63_12015 AFK63_RS11995 2586951 2587565 + hypothetical protein gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS11995 AFK63_RS12000 AFK63_12020 AFK63_RS12000 2588179 2589624 - hypothetical protein gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12000 AFK63_RS12005 AFK63_12025 AFK63_RS12005 2589699 2590073 - hypothetical protein gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12005 AFK63_RS12010 AFK63_12030 AFK63_RS12010 2590565 2592310 - hypothetical protein gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12010 AFK63_RS12015 AFK63_12035 rimO rimO 2592354 2593661 + ribosomal protein S12 methylthiotransferase catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12015 AFK63_RS12020 AFK63_12040 AFK63_RS12020 2593874 2594785 - glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12020 AFK63_RS12025 AFK63_12045 AFK63_RS12025 2594788 2595708 - glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12025 AFK63_RS12030 AFK63_12050 AFK63_RS12030 2595885 2597423 - glutathione ABC transporter substrate-binding protein with GsiACD is involved in the transport of glutathione into the cell gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12030 AFK63_RS12035 AFK63_12055 AFK63_RS12035 2597454 2599328 - glutathione ABC transporter ATP-binding protein with GsiBCD is involved in glutathione import%3B GsiA contains 2 ATP-binding domains gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12035 AFK63_RS12040 AFK63_12060 AFK63_RS12040 2599566 2600795 + molybdopterin biosynthesis protein MoeA is involved in the formation of active molybdenum cofactor and the chelation of molybdenum gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12040 AFK63_RS12045 AFK63_12065 AFK63_RS12045 2600797 2601555 + molybdopterin-synthase adenylyltransferase gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12045 AFK63_RS12050 AFK63_12070 AFK63_RS12050 2601552 2602622 - cytochrome C peroxidase gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12050 AFK63_RS12055 AFK63_12075 AFK63_RS12055 2602928 2604238 + hexuronate transporter involved in the transport of aldohexuronates gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12055 AFK63_RS12060 AFK63_12080 AFK63_RS12060 2604250 2606613 + alpha-glucosidase gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12060 AFK63_RS12065 AFK63_12085 AFK63_RS12065 2606933 2608525 - ATPase component of ABC transporter with duplicated ATPase domain gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12065 AFK63_RS12070 AFK63_12090 AFK63_RS12070 2608746 2609666 + transpeptidase gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12070 AFK63_RS12075 AFK63_12095 AFK63_RS12075 2609733 2611274 - RND transporter gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12075 AFK63_RS12080 AFK63_12100 AFK63_RS12080 2611276 2612847 - MFS transporter gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12080 AFK63_RS12085 AFK63_12105 AFK63_RS12085 2612844 2613989 - multidrug export protein EmrA gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12085 AFK63_RS12090 AFK63_12110 AFK63_RS12090 2614090 2615208 - membrane protein gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12090 AFK63_RS12095 AFK63_12115 AFK63_RS12095 2615211 2615678 - manganese transport regulator MntR Transcriptional regulator that represses the manganese transporter MntH when manganese is present gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12095 AFK63_RS12100 AFK63_12120 AFK63_RS12100 2616286 2617869 + phosphoethanolamine transferase gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12100 AFK63_RS12105 AFK63_12125 ompX ompX 2617927 2618442 - membrane protein OmpX%3B involved in cell adhesion%3B forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface%3B mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12105 AFK63_RS12110 AFK63_12130 AFK63_RS12110 2618794 2619681 + threonine transporter gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12110 AFK63_RS12115 AFK63_12135 AFK63_RS12115 2619997 2620500 + DNA starvation/stationary phase protection protein Dps binds DNA in a non-sequence-specific manner and is abundant during stationary phase%3B forms a DNA-protein crystal that protects DNA from damage%3B required for normal starvation response and long-term stationary viability%3B forms a homododecameric complex and sequesters iron which provides protection against oxidative damage gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12115 AFK63_RS12120 AFK63_12140 glnH glnH 2620875 2621618 + glutamine ABC transporter substrate-binding protein similar to periplasmic-binding component of ABC transporters gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12120 AFK63_RS12125 AFK63_12145 glnP glnP 2621702 2622361 + glutamine ABC transporter permease similar to permease component of ABC transporters%3B mutations impair ability of Escherichia coli to transport and utilize glutamine gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12125 AFK63_RS12130 AFK63_12150 glnQ glnQ 2622358 2623080 + glutamine ABC transporter ATP-binding protein similar to ATP-binding component of ABC transporters gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12130 AFK63_RS12135 AFK63_12155 AFK63_RS12135 2623359 2625617 + mechanosensitive channel protein gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12135 AFK63_RS12140 AFK63_12160 AFK63_RS12140 2625618 2626547 - 23S rRNA methyltransferase gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12140 AFK63_RS12145 AFK63_12165 AFK63_RS12145 2626660 2627277 + Asp/Glu/hydantoin racemase gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12145 AFK63_RS12150 AFK63_12170 AFK63_RS12150 2627373 2627639 + conjugal transfer protein TraR gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12150 AFK63_RS12155 AFK63_12175 AFK63_RS12155 2627897 2628157 + hypothetical protein gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12155 AFK63_RS12160 AFK63_12180 AFK63_RS12160 2628247 2629215 - glycosyl transferase gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12160 AFK63_RS12165 AFK63_12185 AFK63_RS12165 2629548 2630084 + ferrous iron transporter B gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12165 AFK63_RS12170 AFK63_12190 AFK63_RS12170 2630147 2630812 + long polar fimbrial chaperone LpfB binds with fimbrial subunit LpfA gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12170 AFK63_RS12175 AFK63_12195 AFK63_RS12175 2630869 2633427 + fimbrial assembly protein gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12175 AFK63_RS12180 AFK63_12200 AFK63_RS12180 2633627 2634421 + hypothetical protein gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12180 AFK63_RS12185 AFK63_12205 AFK63_RS12185 2634434 2634940 + hypothetical protein gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12185 AFK63_RS12190 AFK63_12210 dinG dinG 2634927 2637113 - ATP-dependent DNA helicase DinG helicase involved in DNA repair and perhaps also replication gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12190 AFK63_RS12195 AFK63_12215 AFK63_RS12195 2637406 2638251 + transcription antiterminator LicT gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12195 AFK63_RS12200 AFK63_12220 AFK63_RS12200 2638359 2640227 + PTS beta-glucoside transporter subunit IIA gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12200 AFK63_RS12205 AFK63_12225 AFK63_RS12205 2640239 2641711 + aryl-phospho-beta-D-glucosidase gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12205 AFK63_RS12210 AFK63_12230 AFK63_RS12210 2641721 2643112 + aryl-phospho-beta-D-glucosidase gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12210 AFK63_RS12215 AFK63_12235 AFK63_RS12215 2643269 2644594 - 6-phospho-alpha-glucosidase gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12215 AFK63_RS12220 AFK63_12240 AFK63_RS12220 2644607 2646205 - PTS maltose transporter subunit IICB gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12220 AFK63_RS12225 AFK63_12245 AFK63_RS12225 2646342 2647076 - GntR family transcriptional regulator gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12225 AFK63_RS12230 AFK63_12250 AFK63_RS12230 2647147 2648595 - ATP-dependent RNA helicase RhlE this helicase is not essential cell growth gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12230 AFK63_RS12235 AFK63_12255 AFK63_RS12235 2648776 2649192 - membrane protein gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12235 AFK63_RS12240 AFK63_12260 AFK63_RS12240 2649328 2650089 + hypothetical protein gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12240 AFK63_RS12245 AFK63_12265 AFK63_RS12245 2650086 2651327 + cardiolipin synthase 2 gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12245 AFK63_RS12250 AFK63_12270 AFK63_RS12250 2651327 2652355 + membrane protein gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12250 AFK63_RS12255 AFK63_12275 AFK63_RS12255 2652505 2653212 - membrane protein gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12255 AFK63_RS12260 AFK63_12280 moaE moaE 2653318 2653770 - molybdopterin guanine dinucleotide biosynthesis protein MoaE catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12260 AFK63_RS12265 AFK63_12285 moaD moaD 2653772 2654017 - molybdopterin synthase small subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12265 AFK63_RS12270 AFK63_12290 moaC moaC 2654010 2654495 - molybdenum cofactor biosynthesis protein MoaC MoaC%3B along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z%3B involved in molybdenum cofactor biosynthesis gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12270 AFK63_RS12275 AFK63_12295 AFK63_RS12275 2654499 2655011 - molybdopterin biosynthesis protein MoeB gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12275 AFK63_RS12280 AFK63_12300 moaA moaA 2655033 2656022 - cyclic pyranopterin phosphate synthase MoaA together with moaC%2C is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12280 AFK63_RS12285 AFK63_12305 AFK63_RS12285 2656368 2657276 + hypothetical protein gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12285 AFK63_RS12290 AFK63_12310 AFK63_RS12290 2657484 2659505 - excinuclease ABC subunit B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12290 AFK63_RS12295 AFK63_12315 AFK63_RS12295 2660396 2661106 + branched-chain amino acid ABC transporter ATP-binding protein gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12295 AFK63_RS12300 AFK63_12320 bioD bioD 2661111 2661794 - dethiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12300 AFK63_RS12305 AFK63_12325 AFK63_RS12305 2661787 2662545 - malonyl-[acyl-carrier protein] O-methyltransferase BioC methyltransferase%3B acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA%2C a biotin precursor%3B member of the bio operon (bioABFCD)%3B in Escherichia coli%2C bioC-null mutants require biotin for growth gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12305 AFK63_RS12310 AFK63_12330 AFK63_RS12310 2662529 2663680 - 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12310 AFK63_RS12315 AFK63_12335 AFK63_RS12315 2663677 2664717 - biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12315 AFK63_RS12320 AFK63_12340 AFK63_RS12320 2664799 2666091 + adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12320 AFK63_RS12325 AFK63_12345 AFK63_RS12325 2666156 2666836 + dimethylallyltransferase gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12325 AFK63_RS12330 AFK63_12350 AFK63_RS12330 2666850 2667326 + kinase inhibitor YbhB%3B similar to rat and human kinase inhibitory proteins gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12330 AFK63_RS12335 AFK63_12355 AFK63_RS12335 2667438 2668748 + acyl-CoA thioesterase gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12335 AFK63_RS12340 AFK63_12360 AFK63_RS12340 2669333 2670334 - 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12340 AFK63_RS12345 AFK63_12365 AFK63_RS12345 2670487 2671305 + pyridoxal phosphate phosphatase gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12345 AFK63_RS12350 AFK63_12370 modC modC 2671302 2672360 - molybdate transporter ATP-binding protein Part of the ABC transporter complex modABC involved in molybdenum import gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12350 AFK63_RS12355 AFK63_12375 modB modB 2672360 2673052 - molybdate ABC transporter permease part of ModCBA molybdate transporter%3B member of ABC superfamily%3B inner membrane component%3B regulated by repressor protein ModE gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12355 AFK63_RS12360 AFK63_12380 modA modA 2673049 2673825 - molybdate transporter with ModCB is involved in the high-affinity transport of molybdate gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12360 AFK63_RS12365 AFK63_12385 AFK63_RS12365 2674253 2675044 + transcriptional regulator represses the modABCD operon and activates the moaABCD and napFDAGHBC operons gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12365 AFK63_RS12370 AFK63_12390 AFK63_RS12370 2675119 2676591 + molybdenum ABC transporter ATP-binding protein contains 2 ATP-binding cassettes%3B involved in the transport of molybdenum gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12370 AFK63_RS12375 AFK63_12395 AFK63_RS12375 2676822 2677838 + UDP-galactose-4-epimerase gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12375 AFK63_RS12380 AFK63_12400 AFK63_RS12380 2677849 2678895 + galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12380 AFK63_RS12385 AFK63_12405 AFK63_RS12385 2678898 2680046 + galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12385 AFK63_RS12390 AFK63_12410 galM galM 2680040 2681080 + galactose-1-epimerase mutarotase%3B catalyzes the conversion of beta-galactose to the alpha-anomer%3B links the metabolism of lactose and galactose gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12390 AFK63_RS12395 AFK63_12415 gpmA gpmA 2681292 2682044 + 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12395 AFK63_RS12400 AFK63_12420 AFK63_RS12400 2682225 2683277 - phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12400 AFK63_RS12405 AFK63_12425 AFK63_RS12405 2683602 2684000 + hypothetical protein gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12405 AFK63_RS12410 AFK63_12430 AFK63_RS12410 2684131 2685084 + zinc transporter ZitB involved in zinc efflux across the cytoplasmic membrane gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12410 AFK63_RS12415 AFK63_12435 AFK63_RS12415 2685081 2685800 - nicotinamide riboside transporter PnuC involved in nicotinamide riboside transport gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12415 AFK63_RS12420 AFK63_12440 AFK63_RS12420 2685824 2686885 - quinolinate synthetase 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12420 AFK63_RS12425 AFK63_12445 AFK63_RS12425 2687658 2687733 - tRNA-Lys tRNA gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12425 AFK63_RS12430 AFK63_12450 AFK63_RS12430 2687870 2687945 - tRNA-Lys tRNA gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12430 AFK63_RS12435 AFK63_12455 AFK63_RS12435 2688082 2688157 - tRNA-Lys tRNA gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12435 AFK63_RS12440 AFK63_12460 AFK63_RS12440 2688321 2688396 - tRNA-Lys tRNA gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12440 AFK63_RS12445 AFK63_12465 AFK63_RS12445 2688400 2688475 - tRNA-Val tRNA gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12445 AFK63_RS12450 AFK63_12470 AFK63_RS12450 2688584 2688659 - tRNA-Lys tRNA gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12450 AFK63_RS12455 AFK63_12475 AFK63_RS12455 2688824 2689621 - tol-pal system protein periplasmic protein that interacts with TolA%3B the tol-pal system is probably involved in maintaining cell envelope integrity gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12455 AFK63_RS12460 AFK63_12480 AFK63_RS12460 2689631 2690149 - hypothetical protein gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12460 AFK63_RS12465 AFK63_12485 tolB tolB 2690184 2691476 - translocation protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12465 AFK63_RS12470 AFK63_12490 tolA tolA 2691603 2692871 - protein TolA inner membrane component of 7 member Tol-Pal envelope-spanning complex%3B involved in maintaining cell envelope integrity%3B utilized by colicins and filamentous phages for import%3B interacts with TolB%2C Pal%2C and through TolB to various outer membrane porins gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12470 AFK63_RS12475 AFK63_12495 AFK63_RS12475 2692912 2693340 - colicin transporter TolR membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12475 AFK63_RS12480 AFK63_12500 AFK63_RS12480 2693344 2694033 - colicin transporter TolQ membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12480 AFK63_RS12485 AFK63_12505 AFK63_RS12485 2694039 2694443 - acyl-CoA thioesterase catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters%3B physiological role remains unknown%3B involved in phospholipid metabolism%3B part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12485 AFK63_RS12490 AFK63_12510 AFK63_RS12490 2694577 2694870 - cytochrome bd biosynthesis protein gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12490 AFK63_RS12495 AFK63_12515 AFK63_RS12495 2694997 2696136 - cytochrome d ubiquinol oxidase subunit II gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12495 AFK63_RS12500 AFK63_12520 AFK63_RS12500 2696152 2697720 - cytochrome d terminal oxidase subunit I part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12500 AFK63_RS12505 AFK63_12525 AFK63_RS12505 2698692 2699561 - succinyl-CoA synthetase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12505 AFK63_RS12510 AFK63_12530 sucC sucC 2699561 2700727 - succinyl-CoA ligase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12510 AFK63_RS12515 AFK63_12535 AFK63_RS12515 2700838 2702061 - dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12515 AFK63_RS12520 AFK63_12540 AFK63_RS12520 2702076 2704883 - 2-oxoglutarate dehydrogenase gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12520 AFK63_RS12525 AFK63_12545 sdhB sdhB 2705250 2705966 - succinate dehydrogenase iron-sulfur subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol%3B the catalytic subunits are similar to fumarate reductase gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12525 AFK63_RS12530 AFK63_12550 sdhA sdhA 2705982 2707748 - succinate dehydrogenase part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12530 AFK63_RS12535 AFK63_12555 sdhD sdhD 2707749 2708096 - succinate dehydrogenase cytochrome b556 small membrane subunit gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12535 AFK63_RS12540 AFK63_12560 sdhC sdhC 2708090 2708479 - succinate dehydrogenase cytochrome b-556 subunit gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12540 AFK63_RS12545 AFK63_12565 gltA gltA 2709133 2710419 + type II citrate synthase type II enzyme%3B in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate%3B allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation%3B forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A%3B functions in TCA cycle%2C glyoxylate cycle and respiration%3B enzyme from Helicobacter pylori is not inhibited by NADH gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12545 AFK63_RS12550 AFK63_12570 AFK63_RS12550 2710756 2711547 - endonuclease VIII 5-formyluracil/5-hydroxymethyluracil DNA glycosylase%3B involved in base excision repair of DNA damaged by oxidation or by mutagenic agents%3B acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines%3B has apurinic/apyrimidinic lyase activity gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12550 AFK63_RS12555 AFK63_12575 AFK63_RS12555 2711656 2712651 - hypothetical protein gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12555 AFK63_RS12560 AFK63_12580 AFK63_RS12560 2712682 2713668 - membrane protein gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12560 AFK63_RS12565 AFK63_12585 AFK63_RS12565 2713665 2714387 - membrane protein gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12565 AFK63_RS12570 AFK63_12590 AFK63_RS12570 2714635 2715183 + transcriptional regulator gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12570 AFK63_RS12575 AFK63_12595 AFK63_RS12575 2715185 2715919 - LamB/YcsF family protein gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12575 AFK63_RS12580 AFK63_12600 AFK63_RS12580 2715909 2716841 - hypothetical protein gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12580 AFK63_RS12585 AFK63_12605 AFK63_RS12585 2716835 2717491 - hypothetical protein gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12585 AFK63_RS12590 AFK63_12610 AFK63_RS12590 2717512 2718255 - Nif3-like dinuclear metal center hexameric protein gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12590 AFK63_RS12595 AFK63_12615 AFK63_RS12595 2718268 2719689 - deoxyribodipyrimidine photolyase UV-induced DNA repair%3B converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers%3B light dependent gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12595 AFK63_RS12600 AFK63_12620 AFK63_RS12600 2719702 2720658 - membrane protein gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12600 AFK63_RS12605 AFK63_12625 AFK63_RS12605 2720809 2721015 - hypothetical protein gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12605 AFK63_RS12610 AFK63_12630 AFK63_RS12610 2721418 2723100 + potassium-transporting ATPase subunit A catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12610 AFK63_RS12615 AFK63_12635 AFK63_RS12615 2723121 2725169 + potassium-transporting ATPase subunit B One of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12615 AFK63_RS12620 AFK63_12640 AFK63_RS12620 2725181 2725753 + potassium-transporting ATPase subunit C One of the components of the high-affinity ATP-driven potassium transport (or KDP)system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12620 AFK63_RS12625 AFK63_12645 AFK63_RS12625 2725763 2728447 + two-component system sensor histidine kinase KdpD sensory histidine kinase in two-component regulatory system with KdpE%3B signal sensing protein gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12625 AFK63_RS12630 AFK63_12650 AFK63_RS12630 2728444 2729121 + two-component system response regulator response regulator in two-component regulatory system with KdpD%3B regulates the kdp operon involved in potassium transport gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12630 AFK63_RS12635 AFK63_12655 AFK63_RS12635 2729825 2732020 + ornithine decarboxylase gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12635 AFK63_RS12640 AFK63_12660 potE potE 2732020 2733333 + putrescine transporter catalyzes the uptake of putrescine via a proton symport mechanism%2C as well as the efflux of putrescine by a putrescine/ornithine antiport system gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12640 AFK63_RS12645 AFK63_12665 AFK63_RS12645 2733425 2735065 - phosphoglucomutase catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12645 AFK63_RS12650 AFK63_12670 AFK63_RS12650 2735090 2735635 - replication initiation regulator SeqA negative modulator of the initiation of chromosome replication gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12650 AFK63_RS12655 AFK63_12675 AFK63_RS12655 2735819 2736586 + acyl-CoA esterase gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12655 AFK63_RS12660 AFK63_12680 AFK63_RS12660 2736714 2736995 + LexA regulated protein gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12660 AFK63_RS12665 AFK63_12685 AFK63_RS12665 2737157 2737687 + flavodoxin FldA An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12665 AFK63_RS12670 AFK63_12690 fur fur 2737977 2738429 + ferric uptake regulator negatively regulates a number of operons that encode enzymes involved in iron transport%3B activated by manganese%3B forms a homodimer gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12670 AFK63_RS12675 AFK63_12695 AFK63_RS12675 2738753 2739364 + hypothetical protein gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12675 AFK63_RS12680 AFK63_12700 AFK63_RS12680 2739423 2742074 - beta-N-acetylhexosaminidase gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12680 AFK63_RS12685 AFK63_12705 chiP chiP 2742131 2743528 - chitoporin outer membrane porin involved in the transport of chitooligosaccharides gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12685 AFK63_RS12690 AFK63_12710 AFK63_RS12690 2743979 2745646 - glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12690 AFK63_RS12695 AFK63_12715 AFK63_RS12695 2745753 2746169 - hypothetical protein gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12695 AFK63_RS12700 AFK63_12720 AFK63_RS12700 2746298 2748280 - PTS N-acetyl glucosamine transporter subunit IIABC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12700 AFK63_RS12705 AFK63_12725 nagB nagB 2748639 2749439 + glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12705 AFK63_RS12710 AFK63_12730 nagA nagA 2749461 2750609 + N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12710 AFK63_RS12715 AFK63_12735 AFK63_RS12715 2750618 2751838 + transcriptional regulator regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12715 AFK63_RS12720 AFK63_12740 AFK63_RS12720 2751900 2752652 + UMP phosphatase gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12720 AFK63_RS12725 AFK63_12745 asnB asnB 2752949 2754613 + asparagine synthetase B functions in asparagine biosynthesis%3B converts glutamine%2C aspartate%2C ATP%2C and water to glutamate%2C asparagine%2C pyrophosphate and AMP gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12725 AFK63_RS12730 AFK63_12750 AFK63_RS12730 2754864 2754940 + tRNA-Met tRNA gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12730 AFK63_RS12735 AFK63_12755 AFK63_RS12735 2754949 2755033 + tRNA-Leu tRNA gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12735 AFK63_RS12740 AFK63_12760 AFK63_RS12740 2755057 2755131 + tRNA-Gln tRNA gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12740 AFK63_RS12745 AFK63_12765 AFK63_RS12745 2755168 2755242 + tRNA-Gln tRNA gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12745 AFK63_RS12750 AFK63_12770 AFK63_RS12750 2755273 2755349 + tRNA-Met tRNA gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12750 AFK63_RS12755 AFK63_12775 AFK63_RS12755 2755411 2755485 + tRNA-Gln tRNA gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12755 AFK63_RS12760 AFK63_12780 AFK63_RS12760 2755577 2755651 + tRNA-Gln tRNA gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12760 AFK63_RS12765 AFK63_12785 ubiF ubiF 2755899 2757074 - 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol%3B functions in the biosynthesis of ubiquinone or coenzyme Q gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12765 AFK63_RS12770 AFK63_12790 AFK63_RS12770 2757220 2758644 + dimethylallyladenosine tRNA methylthiotransferase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12770 AFK63_RS12775 AFK63_12795 AFK63_RS12775 2758848 2759909 + nucleoside triphosphate hydrolase gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12775 AFK63_RS12780 AFK63_12800 AFK63_RS12780 2759906 2760373 + 16S rRNA maturation RNase YbeY gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12780 AFK63_RS12785 AFK63_12805 AFK63_RS12785 2760476 2761351 + Magnesium and cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12785 AFK63_RS12790 AFK63_12810 lnt lnt 2761356 2762897 + apolipoprotein acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12790 AFK63_RS12795 AFK63_12815 AFK63_RS12795 2763248 2764153 + amino acid transporter gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12795 AFK63_RS12800 AFK63_12820 AFK63_RS12800 2764317 2765057 + amino acid ABC transporter permease with GltIKL is involved in the transport of glutamate and aspartate gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12800 AFK63_RS12805 AFK63_12825 AFK63_RS12805 2765057 2765731 + amino acid ABC transporter permease with GltJLPS and GadC for glutamate and GltJLP%2C DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12805 AFK63_RS12810 AFK63_12830 artP artP 2765731 2766456 + glutamate ABC transporter ATP-binding protein With ArtMQJI transports arginine across the inner membrane gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12810 AFK63_RS12815 AFK63_12835 AFK63_RS12815 2766501 2767760 - hypothetical protein gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12815 AFK63_RS12820 AFK63_12840 AFK63_RS12820 2767839 2768027 + hypothetical protein gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12820 AFK63_RS12825 AFK63_12845 AFK63_RS12825 2768208 2768690 - hypothetical protein gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12825 AFK63_RS12830 AFK63_12850 leuS leuS 2768895 2771501 + leucyl-tRNA synthetase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12830 AFK63_RS12835 AFK63_12855 AFK63_RS12835 2771516 2772115 + LPS-assembly lipoprotein RlpB gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12835 AFK63_RS12840 AFK63_12860 holA holA 2772115 2773146 + DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12840 AFK63_RS12845 AFK63_12865 AFK63_RS12845 2773139 2773810 + nicotinate-nucleotide adenylyltransferase gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12845 AFK63_RS12850 AFK63_12870 AFK63_RS12850 2774051 2774368 + ribosome silencing factor RsfS gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12850 AFK63_RS12855 AFK63_12875 AFK63_RS12855 2774372 2774839 + ribosomal RNA large subunit methyltransferase H gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12855 AFK63_RS12860 AFK63_12880 AFK63_RS12860 2774866 2776767 + penicillin-binding protein 2 gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12860 AFK63_RS12865 AFK63_12885 AFK63_RS12865 2776769 2777881 + cell wall shape-determining protein gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12865 AFK63_RS12870 AFK63_12890 AFK63_RS12870 2777892 2779061 + lipoprotein gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12870 AFK63_RS12875 AFK63_12895 AFK63_RS12875 2779204 2780418 + D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 5%3B removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12875 AFK63_RS12880 AFK63_12900 AFK63_RS12880 2780524 2780787 + lipoate regulatory protein YbeD gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12880 AFK63_RS12885 AFK63_12905 AFK63_RS12885 2780866 2781507 + lipoate--protein ligase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12885 AFK63_RS12890 AFK63_12910 AFK63_RS12890 2781828 2782823 + transcriptional regulator gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12890 AFK63_RS12895 AFK63_12915 AFK63_RS12895 2783015 2783980 + lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12895 AFK63_RS12900 AFK63_12920 tatE tatE 2784070 2784273 - sec-independent protein translocase tatE TatE%3B similar to TatA and found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12900 AFK63_RS12905 AFK63_12925 AFK63_RS12905 2784400 2785188 - hydrolase gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12905 AFK63_RS12910 AFK63_12930 AFK63_RS12910 2785274 2785657 + camphor resistance protein CrcB camphor resistance protein CrcB%3B may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12910 AFK63_RS12915 AFK63_12935 AFK63_RS12915 2785885 2786094 - cold-shock protein CspE gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12915 AFK63_RS12920 AFK63_12940 AFK63_RS12920 2786285 2786863 - Lipid A palmitoyltransferase PagP gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12920 AFK63_RS12925 AFK63_12945 dcuC dcuC 2787353 2788714 + C4-dicarboxylate transporter responsible for the transport of C4-dicarboxylates during anaerobic growth gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12925 AFK63_RS12930 AFK63_12950 AFK63_RS12930 2788822 2789628 + ribonuclease I gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12930 AFK63_RS12935 AFK63_12955 AFK63_RS12935 2789648 2789929 - hypothetical protein gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12935 AFK63_RS12940 AFK63_12960 AFK63_RS12940 2790014 2791690 - oligo-1%2C6-glucosidase gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12940 AFK63_RS12945 AFK63_12965 AFK63_RS12945 2791690 2793345 - oligo-1%2C6-glucosidase gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12945 AFK63_RS12950 AFK63_12970 AFK63_RS12950 2793355 2794470 - ABC transporter gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12950 AFK63_RS12955 AFK63_12975 AFK63_RS12955 2794474 2795319 - sugar ABC transporter permease gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12955 AFK63_RS12960 AFK63_12980 AFK63_RS12960 2795319 2796272 - ABC transporter permease gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12960 AFK63_RS12965 AFK63_12985 AFK63_RS12965 2796487 2797752 - ABC transporter substrate-binding protein gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12965 AFK63_RS12970 AFK63_12990 AFK63_RS12970 2798144 2799520 + permease gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12970 AFK63_RS12975 AFK63_12995 AFK63_RS12975 2799672 2800082 + elongation factor GreAB gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12975 AFK63_RS12980 AFK63_13000 AFK63_RS12980 2800146 2801378 - alcohol dehydrogenase gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12980 AFK63_RS12985 AFK63_13005 AFK63_RS12985 2801620 2802048 + universal stress protein UspG interacts with GroEL%3B is induced by starvation%2C heat shock and toxic agents gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12985 AFK63_RS12990 AFK63_13010 AFK63_RS12990 2802371 2803936 - alkyl hydroperoxide reductase gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12990 AFK63_RS12995 AFK63_13015 AFK63_RS12995 2804197 2804760 - alkyl hydroperoxide reductase with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols%3B AhpC reduced the hydroperoxide substrate gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS12995 AFK63_RS13000 AFK63_13020 AFK63_RS13000 2805341 2806303 + LysR family transcriptional regulator gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13000 AFK63_RS13005 AFK63_13025 AFK63_RS13005 2806298 2807458 - methionine aminotransferase catalyzes the transfer of an amino moiety%3B preference for methionine followed by histidine and phenylalanine gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13005 AFK63_RS13010 AFK63_13030 AFK63_RS13010 2807595 2808209 + methylthioribulose-1-phosphate dehydratase catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13010 AFK63_RS13015 AFK63_13035 AFK63_RS13015 2808206 2808895 + 2%2C3-diketo-5-methylthio-1-phosphopentane phosphatase gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13015 AFK63_RS13020 AFK63_13040 AFK63_RS13020 2808892 2809434 + acireductone dioxygenase gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13020 AFK63_RS13025 AFK63_13045 entF entF 2809745 2813605 - enterobactin synthase subunit F with EntB%2C EntD%2C and EntE forms the multienzyme complex enterobactin synthase%3B EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13025 AFK63_RS13030 AFK63_13050 AFK63_RS13030 2813682 2813903 - invasin gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13030 AFK63_RS13035 AFK63_13055 AFK63_RS13035 2813919 2815148 - enterobactin esterase gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13035 AFK63_RS13040 AFK63_13060 AFK63_RS13040 2815430 2817703 + outer membrane receptor protein Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13040 AFK63_RS13045 AFK63_13065 AFK63_RS13045 2817703 2818398 + 4'-phosphopantetheinyl transferase gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13045 AFK63_RS13050 AFK63_13070 AFK63_RS13050 2818395 2819099 - GCN5 family acetyltransferase gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13050 AFK63_RS13055 AFK63_13075 AFK63_RS13055 2819285 2820400 + gamma-glutamyl ligase gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13055 AFK63_RS13060 AFK63_13080 AFK63_RS13060 2820660 2822567 + chemotaxis protein gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13060 AFK63_RS13065 AFK63_13085 AFK63_RS13065 2823181 2823714 - membrane protein gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13065 AFK63_RS13070 AFK63_13090 AFK63_RS13070 2823716 2824021 - transcriptional regulator gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13070 AFK63_RS13075 AFK63_13095 AFK63_RS13075 2824468 2825661 + MFS transporter gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13075 AFK63_RS13080 AFK63_13100 AFK63_RS13080 2825731 2826084 + membrane protein gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13080 AFK63_RS13085 AFK63_13105 AFK63_RS13085 2826136 2826615 - RES domain-containing protein gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13085 AFK63_RS13090 AFK63_13110 AFK63_RS13090 2826676 2827059 - HxlR family transcriptional regulator gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13090 AFK63_RS13095 AFK63_13115 AFK63_RS13095 2827158 2827886 + oxidoreductase gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13095 AFK63_RS13100 AFK63_13120 AFK63_RS13100 2828108 2828590 + glutathione peroxidase gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13100 AFK63_RS13105 AFK63_13125 AFK63_RS13105 2828856 2828932 - tRNA-Arg tRNA gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13105 AFK63_RS13110 AFK63_13130 AFK63_RS13110 2829140 2830006 + methenyltetrahydrofolate cyclohydrolase gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13110 AFK63_RS13115 AFK63_13135 AFK63_RS13115 2830008 2830220 + ribosome-associated protein gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13115 AFK63_RS13120 AFK63_13140 AFK63_RS13120 2830498 2831997 + PTS N-acetylglucosamine transporter subunit IICB phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13120 AFK63_RS13125 AFK63_13145 AFK63_RS13125 2832060 2833076 + LacI family transcriptional regulator gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13125 AFK63_RS13130 AFK63_13150 cysS cysS 2833222 2834607 - cysteinyl-tRNA synthetase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13130 AFK63_RS13135 AFK63_13155 AFK63_RS13135 2834784 2835278 + peptidylprolyl isomerase gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13135 AFK63_RS13140 AFK63_13160 AFK63_RS13140 2835282 2836004 + UDP-2%2C3-diacylglucosamine hydrolase catalyzes the formation of 2%2C3%3Ddiacylglucosamine 1-phosphate from UDP-2%2C3%3Ddiacylglucosamine gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13140 AFK63_RS13145 AFK63_13165 purE purE 2836138 2836647 + N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13145 AFK63_RS13150 AFK63_13170 AFK63_RS13150 2836644 2837711 + phosphoribosylaminoimidazole carboxylase gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13150 AFK63_RS13155 AFK63_13175 AFK63_RS13155 2837864 2839009 - cystathionine beta-lyase gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13155 AFK63_RS13160 AFK63_13180 AFK63_RS13160 2839021 2840391 - cystathionine beta-synthase gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13160 AFK63_RS13165 AFK63_13185 AFK63_RS13165 2840723 2841382 - methionine ABC transporter permease gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13165 AFK63_RS13170 AFK63_13190 AFK63_RS13170 2841375 2842388 - methionine ABC transporter ATP-binding protein gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13170 AFK63_RS13175 AFK63_13195 AFK63_RS13175 2842450 2843280 - methionine ABC transporter ATPase gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13175 AFK63_RS13180 AFK63_13200 AFK63_RS13180 2843528 2845942 - sugar ABC transporter permease gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13180 AFK63_RS13185 AFK63_13205 AFK63_RS13185 2845939 2846625 - ABC transporter ATP-binding protein gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13185 AFK63_RS13190 AFK63_13210 AFK63_RS13190 2846593 2847222 + acyl-CoA thioesterase gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13190 AFK63_RS13195 AFK63_13215 AFK63_RS13195 2847251 2848021 + oxidoreductase gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13195 AFK63_RS13200 AFK63_13220 AFK63_RS13200 2848080 2848934 + hypothetical protein gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13200 AFK63_RS13205 AFK63_13225 AFK63_RS13205 2849045 2849962 + protease gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13205 AFK63_RS13210 AFK63_13230 AFK63_RS13210 2849959 2850414 + membrane protein gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13210 AFK63_RS13215 AFK63_13235 AFK63_RS13215 2850508 2852661 + hypothetical protein gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13215 AFK63_RS13220 AFK63_13240 AFK63_RS13220 2852631 2853350 + hypothetical protein gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13220 AFK63_RS13225 AFK63_13245 AFK63_RS13225 2853354 2853764 - transcriptional regulator activator of copper-responsive regulon genes gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13225 AFK63_RS13230 AFK63_13250 copA copA 2853873 2856380 + copper-transporting ATPase gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13230 AFK63_RS13235 AFK63_13255 AFK63_RS13235 2856561 2857358 + conjugal transfer protein TraB gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13235 AFK63_RS13240 AFK63_13260 AFK63_RS13240 2857559 2858038 + hypothetical protein gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13240 AFK63_RS13245 AFK63_13265 ushA ushA 2858040 2859692 - 5'-nucleotidase catalyzes the degradation of periplasmic UDP-glucose to uridine%2C glucose-1-phosphate and inorganic phosphate%3B specific for uridine nucleotides gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13245 AFK63_RS13250 AFK63_13270 AFK63_RS13250 2859720 2859932 + hypothetical protein gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13250 AFK63_RS13255 AFK63_13275 AFK63_RS13255 2860215 2861897 + cation:proton antiport protein YbaL%3B member of the CPA-2 family of antiporters%3B uncharacterized protein gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13255 AFK63_RS13260 AFK63_13280 AFK63_RS13260 2862415 2863719 - guanosine kinase catalyzes the formation of inosine/guanosine monophosphate from inosine or guanosine and ATP gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13260 AFK63_RS13265 AFK63_13285 AFK63_RS13265 2863783 2864745 - ferrochelatase gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13265 AFK63_RS13270 AFK63_13290 AFK63_RS13270 2864866 2866020 - glycerate kinase gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13270 AFK63_RS13275 AFK63_13295 AFK63_RS13275 2866031 2867296 - gluconate:proton symporter gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13275 AFK63_RS13280 AFK63_13300 AFK63_RS13280 2867417 2868550 - XRE family transcriptional regulator gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13280 AFK63_RS13285 AFK63_13305 adk adk 2868697 2869341 - adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13285 AFK63_RS13290 AFK63_13310 AFK63_RS13290 2869650 2871524 - heat-shock protein Hsp90 molecular chaperone gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13290 AFK63_RS13295 AFK63_13315 recR recR 2871683 2872288 - Recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13295 AFK63_RS13300 AFK63_13320 AFK63_RS13300 2872463 2872795 - nucleoid-associated protein gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13300 AFK63_RS13305 AFK63_13325 AFK63_RS13305 2872877 2874877 - DNA polymerase III subunit gamma/tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13305 AFK63_RS13310 AFK63_13330 AFK63_RS13310 2874967 2875518 - adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13310 AFK63_RS13315 AFK63_13335 AFK63_RS13315 2875670 2876047 - hypothetical protein gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13315 AFK63_RS13320 AFK63_13340 AFK63_RS13320 2876114 2876629 + primosomal protein gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13320 AFK63_RS13325 AFK63_13345 AFK63_RS13325 2876849 2880307 - hypothetical protein gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13325 AFK63_RS13330 AFK63_13350 AFK63_RS13330 2880340 2881005 - transcriptional regulator gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13330 AFK63_RS13335 AFK63_13355 AFK63_RS13335 2881150 2882355 + MexE family multidrug efflux RND transporter periplasmic adaptor subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13335 AFK63_RS13340 AFK63_13360 AFK63_RS13340 2882377 2885526 + multidrug efflux RND transporter permease subunit gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13340 AFK63_RS13345 AFK63_13365 AFK63_RS13345 2886029 2886403 + Hha toxicity attenuator gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13345 AFK63_RS13350 AFK63_13370 AFK63_RS13350 2886430 2886648 + transcriptional regulator with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13350 AFK63_RS13355 AFK63_13375 AFK63_RS13355 2886878 2887429 + maltose acetyltransferase gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13355 AFK63_RS13360 AFK63_13380 AFK63_RS13360 2887549 2888058 + membrane protein gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13360 AFK63_RS13365 AFK63_13385 rpmJ rpmJ 2888087 2888227 - 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group do not have the motif gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13365 AFK63_RS13370 AFK63_13390 AFK63_RS13370 2888231 2888491 - 50S ribosomal protein L31 gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13370 AFK63_RS13375 AFK63_13395 AFK63_RS13375 2888637 2890538 - chemotaxis protein gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13375 AFK63_RS13380 AFK63_13400 AFK63_RS13380 2890896 2891933 + 2-oxobutyrate oxidase gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13380 AFK63_RS13385 AFK63_13405 AFK63_RS13385 2891958 2892761 + metal ABC transporter substrate-binding protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13385 AFK63_RS13390 AFK63_13410 AFK63_RS13390 2892758 2893459 + methionine ABC transporter ATP-binding protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13390 AFK63_RS13395 AFK63_13415 AFK63_RS13395 2893534 2894205 + metal ABC transporter permease gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13395 AFK63_RS13400 AFK63_13420 AFK63_RS13400 2894367 2895923 + hypothetical protein gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13400 AFK63_RS13405 AFK63_13425 AFK63_RS13405 2895916 2896743 - acetyltransferase gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13405 AFK63_RS13410 AFK63_13430 AFK63_RS13410 2896800 2897417 - membrane protein gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13410 AFK63_RS13415 AFK63_13435 AFK63_RS13415 2897504 2898928 + DeoR family transcriptional regulator gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13415 AFK63_RS13420 AFK63_13440 AFK63_RS13420 2899184 2899405 - hypothetical protein gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13420 AFK63_RS13425 AFK63_13445 AFK63_RS13425 2899402 2899653 - hypothetical protein gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13425 AFK63_RS13430 AFK63_13450 AFK63_RS13430 2900372 2900683 + cysteine methyltransferase gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13430 AFK63_RS13435 AFK63_13455 AFK63_RS13435 2900715 2901287 - hypothetical protein gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13435 AFK63_RS13440 AFK63_13460 AFK63_RS13440 2901511 2902371 + acyl-CoA thioesterase gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13440 AFK63_RS13445 AFK63_13465 AFK63_RS13445 2902578 2903864 - ammonium transporter gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13445 AFK63_RS13450 AFK63_13470 AFK63_RS13450 2903896 2904234 - nitrogen regulatory protein P-II indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13450 AFK63_RS13455 AFK63_13475 AFK63_RS13455 2904466 2906244 - multidrug ABC transporter ATP-binding protein gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13455 AFK63_RS13460 AFK63_13480 AFK63_RS13460 2906237 2908012 - multidrug ABC transporter ATP-binding protein gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13460 AFK63_RS13465 AFK63_13485 AFK63_RS13465 2908070 2908531 - transcriptional regulator gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13465 AFK63_RS13470 AFK63_13490 AFK63_RS13470 2908647 2909705 + cysteine synthase gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13470 AFK63_RS13475 AFK63_13495 AFK63_RS13475 2909677 2909934 + hypothetical protein gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13475 AFK63_RS13480 AFK63_13500 AFK63_RS13480 2910105 2910557 + hypothetical protein gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13480 AFK63_RS13485 AFK63_13505 AFK63_RS13485 2910569 2911963 + hypothetical protein gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13485 AFK63_RS13490 AFK63_13510 AFK63_RS13490 2913029 2913583 + hypothetical protein gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13490 AFK63_RS13495 AFK63_13515 AFK63_RS13495 2913646 2914446 - thiamin pyrimidine pyrophosphate hydrolase HMP-PP phosphatase%3B catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13495 AFK63_RS13500 AFK63_13520 AFK63_RS13500 2914537 2916267 + peptide ABC transporter substrate-binding protein gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13500 AFK63_RS13505 AFK63_13525 AFK63_RS13505 2916297 2916992 + 7-cyano-7-deazaguanine synthase YbaX%3B catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0)%2C as one of the early reactions of quenosine biosynthesis%3B quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn%2C Asp%2C Tyr%2C and His gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13505 AFK63_RS13510 AFK63_13530 AFK63_RS13510 2916985 2917821 - MBL fold metallo-hydrolase gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13510 AFK63_RS13515 AFK63_13535 AFK63_RS13515 2918795 2919193 - thioesterase gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13515 AFK63_RS13520 AFK63_13540 AFK63_RS13520 2919319 2919687 - competence protein ComEA gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13520 AFK63_RS13525 AFK63_13545 AFK63_RS13525 2919834 2921711 - molecular chaperone gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13525 AFK63_RS13530 AFK63_13550 AFK63_RS13530 2921924 2922196 - DNA-binding protein HU-beta histone-like DNA-binding protein gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13530 AFK63_RS13535 AFK63_13555 AFK63_RS13535 2922405 2924630 - DNA-binding protein gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13535 AFK63_RS13540 AFK63_13560 clpX clpX 2924945 2926219 - ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13540 AFK63_RS13545 AFK63_13565 AFK63_RS13545 2926342 2926965 - Clp protease proteolytic subunit ClpP gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13545 AFK63_RS13550 AFK63_13570 AFK63_RS13550 2927265 2928563 - trigger factor gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13550 AFK63_RS13555 AFK63_13575 AFK63_RS13555 2928914 2929231 - BolA family transcriptional regulator positive transcriptional regulator of morphogenetic pathway%3B controlling several genes involved in oxidative stress%2C acid stress%2C heat shock%2C osmotic shock%2C and carbon-starvation stress gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13555 AFK63_RS13560 AFK63_13580 AFK63_RS13560 2929531 2930109 + hypothetical protein gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13560 AFK63_RS13565 AFK63_13585 ampG ampG 2930164 2931648 + AmpG family muropeptide MFS transporter in Escherichia coli this protein is a permease involved in peptidoglycan recycling%3B member of major facilitator superfamily%3B MFS%3B inner membrane protein gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13565 AFK63_RS13570 AFK63_13590 AFK63_RS13570 2931637 2932977 - molecular chaperone DnaJ gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13570 AFK63_RS13575 AFK63_13595 AFK63_RS13575 2932977 2934677 - heat-shock protein 70 gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13575 AFK63_RS13580 AFK63_13600 AFK63_RS13580 2935198 2936145 + cytochrome o ubiquinol oxidase subunit II gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13580 AFK63_RS13585 AFK63_13605 AFK63_RS13585 2936165 2938156 + cytochrome o ubiquinol oxidase subunit I gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13585 AFK63_RS13590 AFK63_13610 AFK63_RS13590 2938146 2938763 + cytochrome o ubiquinol oxidase subunit III gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13590 AFK63_RS13595 AFK63_13615 AFK63_RS13595 2938763 2939092 + cytochrome O ubiquinol oxidase gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13595 AFK63_RS13600 AFK63_13620 AFK63_RS13600 2939104 2939991 + protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13600 AFK63_RS13605 AFK63_13625 AFK63_RS13605 2940163 2941527 + membrane protein gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13605 AFK63_RS13610 AFK63_13630 AFK63_RS13610 2941599 2942090 - hypothetical protein nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ%3B the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13610 AFK63_RS13615 AFK63_13635 AFK63_RS13615 2942243 2943157 + 2-dehydropantoate 2-reductase ketopantoate reductase%3B catalyzes the NADPH reduction of ketopantoate to pantoate%3B functions in pantothenate (vitamin B5) biosynthesis gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13615 AFK63_RS13620 AFK63_13640 AFK63_RS13620 2943117 2943710 + oxidative-stress-resistance chaperone gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13620 AFK63_RS13625 AFK63_13645 AFK63_RS13625 2943792 2945240 - tRNA s(4)U8 sulfurtransferase catalyzes the conversion of uridine to 4-thiouridinine tRNA%3B also required for the synthesis of the thiazole moiety gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13625 AFK63_RS13630 AFK63_13650 AFK63_RS13630 2945453 2945695 + exodeoxyribonuclease VII small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13630 AFK63_RS13635 AFK63_13655 AFK63_RS13635 2945698 2946597 + geranyl transferase gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13635 AFK63_RS13640 AFK63_13660 AFK63_RS13640 2946625 2948487 + 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13640 AFK63_RS13645 AFK63_13665 AFK63_RS13645 2948557 2949531 + oxidoreductase gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13645 AFK63_RS13650 AFK63_13670 AFK63_RS13650 2949571 2950092 - phosphatidylglycerophosphatase hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13650 AFK63_RS13655 AFK63_13675 AFK63_RS13655 2950067 2951047 - thiamine monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13655 AFK63_RS13660 AFK63_13680 nusB nusB 2951234 2951653 - N utilization substance protein B homolog Regulates rRNA biosynthesis by transcriptional antitermination gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13660 AFK63_RS13665 AFK63_13685 ribH ribH 2951675 2952145 - 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13665 AFK63_RS13670 AFK63_13690 ribD ribD 2952233 2953336 - 5-amino-6-(5-phosphoribosylamino)uracil reductase riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13670 AFK63_RS13675 AFK63_13695 AFK63_RS13675 2953340 2953789 - NrdR family transcriptional regulator gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13675 AFK63_RS13680 AFK63_13700 AFK63_RS13680 2953944 2954504 + lipoprotein gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13680 AFK63_RS13685 AFK63_13705 AFK63_RS13685 2954845 2955723 + nucleoside-specific channel-forming protein Tsx receptor of phage T6 and colicin K%3B involved in the transfer of deoxyribo- and ribo-nucleotides across the outer membrane gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13685 AFK63_RS13690 AFK63_13710 AFK63_RS13690 2955918 2956889 - preprotein translocase subunit SecF gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13690 AFK63_RS13695 AFK63_13715 secD secD 2956900 2958714 - preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13695 AFK63_RS13700 AFK63_13720 yajC yajC 2958775 2959107 - preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13700 AFK63_RS13705 AFK63_13725 tgt tgt 2959129 2960256 - queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13705 AFK63_RS13710 AFK63_13730 queA queA 2960380 2961450 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13710 AFK63_RS13715 AFK63_13735 AFK63_RS13715 2961552 2962133 + ACP phosphodiesterase Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13715 AFK63_RS13720 AFK63_13740 AFK63_RS13720 2962134 2963510 - hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13720 AFK63_RS13725 AFK63_13745 AFK63_RS13725 2963507 2966233 - beta-carotene 15%2C15'-monooxygenase gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13725 AFK63_RS13730 AFK63_13750 AFK63_RS13730 2966318 2968135 - maltodextrin glucosidase gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13730 AFK63_RS13735 AFK63_13755 proY proY 2968305 2969672 - proline-specific permease cryptic permease that may be involved in the transport of proline across the inner membrane%3B in Salmonella typhimurium%2C the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13735 AFK63_RS13740 AFK63_13760 AFK63_RS13740 2969744 2971063 - branched-chain amino acid ABC transporter substrate-binding protein sodium:branched-chain amino acid symporter gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13740 AFK63_RS13745 AFK63_13765 phoR phoR 2971460 2972773 - phosphate regulon sensor protein membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13745 AFK63_RS13750 AFK63_13770 AFK63_RS13750 2972796 2973485 - two-component system response regulator two component response regulator for the phosphate regulon%3B PhoR phosphorylates PhoB gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13750 AFK63_RS13755 AFK63_13775 AFK63_RS13755 2973684 2974898 + exonuclease SbcD with SbcC cleaves DNA hairpin structure%2C also has 5' single-strand endonuclease activity gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13755 AFK63_RS13760 AFK63_13780 AFK63_RS13760 2974895 2978044 + exonuclease SbcC with SbcD cleaves DNA hairpin structures%3B also has 5' single-strand endonuclease activity gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13760 AFK63_RS13765 AFK63_13785 AFK63_RS13765 2978072 2978983 - fructokinase catalyzes phosphorylation of fructose%3B cytosolic enzyme gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13765 AFK63_RS13770 AFK63_13790 AFK63_RS13770 2979110 2980021 + recombination associated protein Required for efficient pilin antigenic variation gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13770 AFK63_RS13775 AFK63_13795 AFK63_RS13775 2980055 2980339 - hypothetical protein gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13775 AFK63_RS13780 AFK63_13800 AFK63_RS13780 2980423 2981100 - AroM protein gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13780 AFK63_RS13785 AFK63_13805 AFK63_RS13785 2981370 2981561 - hypothetical protein gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13785 AFK63_RS13790 AFK63_13810 AFK63_RS13790 2981614 2982138 - shikimate kinase gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13790 AFK63_RS13795 AFK63_13815 AFK63_RS13795 2982499 2983275 + ABC transporter substrate-binding protein gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13795 AFK63_RS13800 AFK63_13820 AFK63_RS13800 2983272 2983727 - hypothetical protein gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13800 AFK63_RS13805 AFK63_13825 AFK63_RS13805 2983727 2984182 - membrane protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13805 AFK63_RS13810 AFK63_13830 AFK63_RS13810 2984192 2984707 - hypothetical protein gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13810 AFK63_RS13815 AFK63_13835 AFK63_RS13815 2984820 2985629 + pyrroline-5-carboxylate reductase catalyzes the formation of L-proline from pyrroline-5-carboxylate gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13815 AFK63_RS13820 AFK63_13840 AFK63_RS13820 2985668 2987086 - arabinose:proton symporter gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13820 AFK63_RS13825 AFK63_13845 AFK63_RS13825 2987792 2988052 - anti-adapter protein IraP gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13825 AFK63_RS13830 AFK63_13850 AFK63_RS13830 2988286 2989488 - multidrug transporter Confers resistance to fosfomycin and deoxycholate gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13830 AFK63_RS13835 AFK63_13855 AFK63_RS13835 2989657 2990358 - extensin gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13835 AFK63_RS13840 AFK63_13860 AFK63_RS13840 2990490 2991590 + D-alanine--D-alanine ligase gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13840 AFK63_RS13845 AFK63_13865 AFK63_RS13845 2991595 2991810 - membrane protein gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13845 AFK63_RS13850 AFK63_13870 AFK63_RS13850 2992168 2992473 + membrane protein gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13850 AFK63_RS13855 AFK63_13875 AFK63_RS13855 2992470 2993576 - hypothetical protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13855 AFK63_RS13860 AFK63_13880 AFK63_RS13860 2993672 2994892 - microcin B17 transporter in Escherichia coli SbmA is involved in uptake of microcin J25%3B functions along with FhuA%2C TonB%2C and ExbB/D in this capacity%3B in Sinorhizobium meliloti%2C BacA is essential and required for symbiosis%3B defects appear to affect the cell envelope gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13860 AFK63_RS13865 AFK63_13885 AFK63_RS13865 2995067 2995600 - isochorismatase gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13865 AFK63_RS13870 AFK63_13890 AFK63_RS13870 2995797 2996954 + beta-lactam-binding protein this protein has no known enzymatic function gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13870 AFK63_RS13875 AFK63_13895 AFK63_RS13875 2996990 2997616 - hypothetical protein gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13875 AFK63_RS13880 AFK63_13900 AFK63_RS13880 2997697 3000474 - membrane protein gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13880 AFK63_RS13885 AFK63_13905 AFK63_RS13885 3000873 3001367 + competence protein ComA gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13885 AFK63_RS13890 AFK63_13910 AFK63_RS13890 3001517 3002494 + delta-aminolevulinic acid dehydratase gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13890 AFK63_RS13895 AFK63_13915 AFK63_RS13895 3002634 3004352 + acyltransferase gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13895 AFK63_RS13900 AFK63_13920 AFK63_RS13900 3005115 3005504 - acid shock protein gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13900 AFK63_RS13905 AFK63_13925 tauD tauD 3005661 3006512 - taurine dioxygenase catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide%3B non-heme iron oxidase%3B allows the use of taurine as an alternative sulfur source%3B forms homodimers gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13905 AFK63_RS13910 AFK63_13930 AFK63_RS13910 3006509 3007336 - taurine transporter subunit gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13910 AFK63_RS13915 AFK63_13935 tauB tauB 3007320 3008099 - taurine transporter ATP-binding subunit Part of the ABC transporter complex tauABC involved in taurine import gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13915 AFK63_RS13920 AFK63_13940 tauA tauA 3008109 3009086 - taurine ABC transporter substrate-binding protein with TauB and TauC is responsible for taurine uptake. gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13920 AFK63_RS13925 AFK63_13945 AFK63_RS13925 3010149 3011081 - homocysteine methyltransferase gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13925 AFK63_RS13930 AFK63_13950 AFK63_RS13930 3011068 3012468 - amino acid transporter gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13930 AFK63_RS13935 AFK63_13955 AFK63_RS13935 3012741 3014153 + cytochrome D ubiquinol oxidase subunit I gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13935 AFK63_RS13940 AFK63_13960 AFK63_RS13940 3014146 3015153 + cytochrome D oxidase subunit II gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13940 AFK63_RS13945 AFK63_13965 AFK63_RS13945 3015506 3015664 + protein hokB gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13945 AFK63_RS13950 AFK63_13970 AFK63_RS13950 3015785 3016813 - ATPase gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13950 AFK63_RS13955 AFK63_13975 AFK63_RS13955 3017021 3018400 + ethanolamine permease gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13955 AFK63_RS13960 AFK63_13980 AFK63_RS13960 3018410 3019798 + ethanolamine ammonia-lyase with EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13960 AFK63_RS13965 AFK63_13985 AFK63_RS13965 3019795 3020580 + ethanolamine ammonia-lyase gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13965 AFK63_RS13970 AFK63_13990 AFK63_RS13970 3020606 3021529 - lipid A biosynthesis palmitoleoyl acyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13970 AFK63_RS13975 AFK63_13995 AFK63_RS13975 3022420 3023175 - DeoR family transcriptional regulator gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13975 AFK63_RS13980 AFK63_14000 AFK63_RS13980 3023260 3023844 + GDP-mannose pyrophosphatase gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13980 AFK63_RS13985 AFK63_14005 AFK63_RS13985 3023855 3024214 + NUDIX hydrolase gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13985 AFK63_RS13990 AFK63_14010 AFK63_RS13990 3024270 3025487 - signal transduction protein gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13990 AFK63_RS13995 AFK63_14015 AFK63_RS13995 3025784 3026803 - LacI family transcriptional regulator gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS13995 AFK63_RS14000 AFK63_14020 AFK63_RS14000 3027008 3028111 + 1%2C4-beta-xylanase gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14000 AFK63_RS14005 AFK63_14025 AFK63_RS14005 3028155 3029507 + sodium:galactoside symporter gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14005 AFK63_RS14010 AFK63_14030 AFK63_RS14010 3029536 3029985 - hypothetical protein gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14010 AFK63_RS14015 AFK63_14035 AFK63_RS14015 3030687 3031310 + calcium ABC transporter ATPase gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14015 AFK63_RS14020 AFK63_14040 AFK63_RS14020 3031307 3032776 + SulP family transporter gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14020 AFK63_RS14025 AFK63_14045 AFK63_RS14025 3032928 3034016 + membrane protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14025 AFK63_RS14030 AFK63_14050 AFK63_RS14030 3034194 3036626 + quinate dehydrogenase gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14030 AFK63_RS14035 AFK63_14055 AFK63_RS14035 3036680 3037615 - LysR family transcriptional regulator gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14035 AFK63_RS14040 AFK63_14060 AFK63_RS14040 3037715 3038149 + hypothetical protein gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14040 AFK63_RS14045 AFK63_14065 AFK63_RS14045 3038159 3038626 + membrane protein gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14045 AFK63_RS14050 AFK63_14070 AFK63_RS14050 3038604 3039476 - LysR family transcriptional regulator gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14050 AFK63_RS14055 AFK63_14075 AFK63_RS14055 3039576 3040082 + phenolic acid decarboxylase gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14055 AFK63_RS14060 AFK63_14080 AFK63_RS14060 3040257 3042083 + glycoside hydrolase family 15 gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14060 AFK63_RS14065 AFK63_14085 AFK63_RS14065 3042139 3042942 - methionine ABC transporter substrate-binding protein gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14065 AFK63_RS14070 AFK63_14090 AFK63_RS14070 3042964 3043632 - methionine ABC transporter permease gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14070 AFK63_RS14075 AFK63_14095 AFK63_RS14075 3043625 3044647 - methionine ABC transporter ATP-binding protein gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14075 AFK63_RS14080 AFK63_14100 AFK63_RS14080 3044924 3046903 - Tat pathway signal protein gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14080 AFK63_RS14085 AFK63_14105 AFK63_RS14085 3047045 3048550 - major myo-inositol transporter IolT gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14085 AFK63_RS14090 AFK63_14110 AFK63_RS14090 3048962 3049861 - myo-inosose-2 dehydratase gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14090 AFK63_RS14095 AFK63_14115 AFK63_RS14095 3049894 3050778 - protein iolH gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14095 AFK63_RS14100 AFK63_14120 AFK63_RS14100 3050816 3051829 - inositol 2-dehydrogenase gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14100 AFK63_RS14105 AFK63_14125 AFK63_RS14105 3051885 3053825 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione hydrolase gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14105 AFK63_RS14110 AFK63_14130 AFK63_RS14110 3054316 3056229 + 5-dehydro-2-deoxygluconokinase gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14110 AFK63_RS14115 AFK63_14135 AFK63_RS14115 3056375 3057229 + Fe-S cluster assembly protein HesB gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14115 AFK63_RS14120 AFK63_14140 AFK63_RS14120 3057278 3058087 - 5-deoxy-glucuronate isomerase gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14120 AFK63_RS14125 AFK63_14145 AFK63_RS14125 3058104 3059609 - methylmalonate-semialdehyde dehydrogenase gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14125 AFK63_RS14130 AFK63_14150 AFK63_RS14130 3059969 3060790 + inosose isomerase gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14130 AFK63_RS14135 AFK63_14155 AFK63_RS14135 3060919 3061191 + hypothetical protein gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14135 AFK63_RS14140 AFK63_14160 AFK63_RS14140 3061228 3062928 - NAD-dependent malic enzyme gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14140 AFK63_RS14145 AFK63_14165 lacY lacY 3063141 3064406 - galactoside permease lactose/proton symporter%3B mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides%3B member of major facilitator superfamily%3B functions as a monomer with 12 transmembrane segments gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14145 AFK63_RS14150 AFK63_14170 lacZ lacZ 3064478 3067609 - beta-D-galactosidase forms a homotetramer%3B hydrolyzes lactose disaccharide to galactose and glucose%3B converts lactose to allolactose which is the natural inducer of the lac operon gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14150 AFK63_RS14155 AFK63_14175 AFK63_RS14155 3067856 3068932 + LacI family transcriptional regulator gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14155 AFK63_RS14160 AFK63_14180 AFK63_RS14160 3069173 3070249 + periplasmic protein gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14160 AFK63_RS14165 AFK63_14185 AFK63_RS14165 3070315 3072489 + TonB-dependent receptor gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14165 AFK63_RS14170 AFK63_14190 AFK63_RS14170 3072525 3073442 - oxidoreductase gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14170 AFK63_RS14175 AFK63_14195 AFK63_RS14175 3073881 3074681 + methyltransferase gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14175 AFK63_RS14180 AFK63_14200 AFK63_RS14180 3074809 3075396 - TetR family transcriptional regulator gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14180 AFK63_RS14185 AFK63_14205 AFK63_RS14185 3075539 3075943 + endoribonuclease L-PSP gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14185 AFK63_RS14190 AFK63_14210 AFK63_RS14190 3075985 3076995 - glyceraldehyde-3-phosphate dehydrogenase gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14190 AFK63_RS14195 AFK63_14215 AFK63_RS14195 3077074 3078054 - AraC family transcriptional regulator gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14195 AFK63_RS14200 AFK63_14220 AFK63_RS14200 3078297 3078593 - hypothetical protein gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14200 AFK63_RS14205 AFK63_14225 AFK63_RS14205 3079415 3079672 + hypothetical protein gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14205 AFK63_RS14210 AFK63_14230 AFK63_RS14210 3079699 3080163 + hypothetical protein gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14210 AFK63_RS14215 AFK63_14235 AFK63_RS14215 3080294 3081352 + peptidase gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14215 AFK63_RS14220 AFK63_14240 AFK63_RS14220 3081600 3082508 + pyrroloquinoline quinone biosynthesis protein PqqB possibly involved in transport of pyrroloquinoline quinone transport gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14220 AFK63_RS14225 AFK63_14245 AFK63_RS14225 3082517 3083272 + pyrroloquinoline quinone biosynthesis protein PqqC Required in the synthesis of PPQ%2C but its exact function is unknown gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14225 AFK63_RS14230 AFK63_14250 AFK63_RS14230 3083272 3083550 + pyrroloquinoline quinone biosynthesis protein PqqD with PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14230 AFK63_RS14235 AFK63_14255 AFK63_RS14235 3083543 3084679 + pyrroloquinoline quinone biosynthesis protein PqqE gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14235 AFK63_RS14240 AFK63_14260 AFK63_RS14240 3084676 3086823 + hypothetical protein gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14240 AFK63_RS14245 AFK63_14265 AFK63_RS14245 3087029 3088624 - peptide ABC transporter substrate-binding protein DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14245 AFK63_RS14250 AFK63_14270 AFK63_RS14250 3088742 3089971 + peptidase T catalyzes the release of the N-terminal amino acid from a tripeptide gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14250 AFK63_RS14255 AFK63_14275 AFK63_RS14255 3090309 3090800 + Hcp family T6SS protein CtsH1 gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14255 AFK63_RS14260 AFK63_14280 AFK63_RS14260 3090797 3091159 + hypothetical protein gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14260 AFK63_RS14265 AFK63_14285 AFK63_RS14265 3091156 3091707 + hypothetical protein gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14265 AFK63_RS14270 AFK63_14290 AFK63_RS14270 3091779 3092222 + hypothetical protein gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14270 AFK63_RS14275 AFK63_14295 AFK63_RS14275 3092302 3092871 - hypothetical protein gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14275 AFK63_RS14280 AFK63_14300 AFK63_RS14280 3095658 3095733 - tRNA-Thr tRNA gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14280 AFK63_RS14285 AFK63_14305 AFK63_RS14285 3095842 3097095 - gamma-glutamyl phosphate reductase gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14285 AFK63_RS14290 AFK63_14310 AFK63_RS14290 3097106 3098209 - glutamate 5-kinase gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14290 AFK63_RS14295 AFK63_14315 AFK63_RS14295 3098501 3099571 + membrane protein gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14295 AFK63_RS14300 AFK63_14320 AFK63_RS14300 3099689 3100078 - hypothetical protein gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14300 AFK63_RS14305 AFK63_14325 frsA frsA 3100136 3101383 - fermentation/respiration switch protein forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc%3B FrsA may promote fermentation gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14305 AFK63_RS14310 AFK63_14330 AFK63_RS14310 3101489 3101947 - xanthine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14310 AFK63_RS14315 AFK63_14335 AFK63_RS14315 3102208 3103665 + aminoacyl-histidine dipeptidase catalyzes the hydrolysis of Xaa-His dipeptides gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14315 AFK63_RS14320 AFK63_14340 AFK63_RS14320 3103876 3104931 - DNA polymerase IV involved in translesion DNA polymerization with beta clamp of polymerase III%3B belongs to Y family of polymerases%3B does not contain proofreading function gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14320 AFK63_RS14325 AFK63_14345 AFK63_RS14325 3105188 3105925 + transpeptidase gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14325 AFK63_RS14330 AFK63_14350 AFK63_RS14330 3105896 3106663 - glutamine amidotransferase gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14330 AFK63_RS14335 AFK63_14355 gmhA gmhA 3106756 3107337 - phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14335 AFK63_RS14340 AFK63_14360 fadE fadE 3107566 3110010 + acyl-CoA dehydrogenase functions in fatty acid oxidation%3B converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14340 AFK63_RS14345 AFK63_14365 AFK63_RS14345 3110117 3110887 + carbon-nitrogen hydrolase NAD(P)-binding gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14345 AFK63_RS14350 AFK63_14370 AFK63_RS14350 3110980 3111056 - tRNA-Asp tRNA gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14350 AFK63_RS14355 AFK63_14375 AFK63_RS14355 3111189 3111920 - DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14355 AFK63_RS14360 AFK63_14380 AFK63_RS14360 3111973 3112449 + ribonuclease H gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14360 AFK63_RS14365 AFK63_14385 AFK63_RS14365 3112446 3113162 - hypothetical protein gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14365 AFK63_RS14370 AFK63_14390 AFK63_RS14370 3113195 3113950 + hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14370 AFK63_RS14375 AFK63_14395 mltD mltD 3114022 3115395 + murein transglycosylase catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues%3B may play a role in recycling muropeptides during cell division and/or cell elongation%3B in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14375 AFK63_RS14380 AFK63_14400 AFK63_RS14380 3115457 3116227 - SAM-dependent methyltransferase gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14380 AFK63_RS14385 AFK63_14405 AFK63_RS14385 3116298 3117101 - hypothetical protein gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14385 AFK63_RS14390 AFK63_14410 AFK63_RS14390 3117233 3118408 - MFS sugar transporter gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14390 AFK63_RS14395 AFK63_14415 AFK63_RS14395 3118510 3119397 + LysR family transcriptional regulator gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14395 AFK63_RS14400 AFK63_14420 dkgB dkgB 3119418 3120221 - 2%2C5-diketo-D-gluconic acid reductase catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14400 AFK63_RS14405 AFK63_14425 AFK63_RS14405 3120375 3120451 - tRNA-Asp tRNA gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14405 AFK63_RS14410 AFK63_14430 AFK63_RS14410 3120506 3120621 - 5S ribosomal RNA rRNA gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14410 AFK63_RS14415 AFK63_14435 AFK63_RS14415 3120699 3123627 - 23S ribosomal RNA rRNA gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14415 AFK63_RS14420 AFK63_14440 AFK63_RS14420 3123788 3123863 - tRNA-Ala tRNA gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14420 AFK63_RS14425 AFK63_14445 AFK63_RS14425 3123897 3123973 - tRNA-Ile tRNA gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14425 AFK63_RS14430 AFK63_14450 AFK63_RS14430 3124033 3125588 - 16S ribosomal RNA rRNA gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14430 AFK63_RS14435 AFK63_14455 AFK63_RS14435 3125965 3126525 - D%2CD-heptose 1%2C7-bisphosphate phosphatase Converts the D-glycero-beta-D-manno-heptose 1%2C7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14435 AFK63_RS14440 AFK63_14460 metN metN 3126716 3127747 + methionine ABC transporter ATP-binding protein part of the metNIQ transport system for methionine gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14440 AFK63_RS14445 AFK63_14465 AFK63_RS14445 3127740 3128393 + methionine ABC transporter permease part of the MetNIQ methionine uptake system gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14445 AFK63_RS14450 AFK63_14470 metQ metQ 3128437 3129252 + methionine ABC transporter substrate-binding protein gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14450 AFK63_RS14455 AFK63_14475 rcsF rcsF 3129365 3129769 + membrane protein gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14455 AFK63_RS14460 AFK63_14480 AFK63_RS14460 3129766 3130473 + tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14460 AFK63_RS14465 AFK63_14485 AFK63_RS14465 3130584 3132302 + prolyl-tRNA synthetase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14465 AFK63_RS14470 AFK63_14490 AFK63_RS14470 3132364 3133053 - copper homeostasis protein gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14470 AFK63_RS14475 AFK63_14495 AFK63_RS14475 3133082 3133504 - hypothetical protein gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14475 AFK63_RS14480 AFK63_14500 AFK63_RS14480 3133501 3134046 - hypothetical protein gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14480 AFK63_RS14485 AFK63_14505 AFK63_RS14485 3134253 3134453 + hypothetical protein gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14485 AFK63_RS14490 AFK63_14510 AFK63_RS14490 3134440 3134700 + Rho-binding antiterminator Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14490 AFK63_RS14495 AFK63_14515 AFK63_RS14495 3134746 3135060 - cytochrome C554 gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14495 AFK63_RS14500 AFK63_14520 tilS tilS 3135053 3136357 - tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%3B ATP-dependent%3B responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14500 AFK63_RS14505 AFK63_14525 AFK63_RS14505 3136422 3136811 - lyase gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14505 AFK63_RS14510 AFK63_14530 AFK63_RS14510 3136869 3139007 - lysine decarboxylase LdcC constitutive%3B catalyzes the formation of cadaverine from lysine gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14510 AFK63_RS14515 AFK63_14535 AFK63_RS14515 3139100 3140860 - chitinase gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14515 AFK63_RS14520 AFK63_14540 AFK63_RS14520 3141023 3141982 - acetyl-CoA carboxylase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14520 AFK63_RS14525 AFK63_14545 dnaE dnaE 3142082 3145564 - DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14525 AFK63_RS14530 AFK63_14550 rnhB rnhB 3145592 3146188 - ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14530 AFK63_RS14535 AFK63_14555 lpxB lpxB 3146185 3147327 - lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14535 AFK63_RS14540 AFK63_14560 AFK63_RS14540 3147327 3148115 - UDP-N-acetylglucosamine acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14540 AFK63_RS14545 AFK63_14565 AFK63_RS14545 3148119 3148574 - 3-hydroxyacyl-ACP dehydratase gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14545 AFK63_RS14550 AFK63_14570 lpxD lpxD 3148691 3149716 - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14550 AFK63_RS14555 AFK63_14575 AFK63_RS14555 3149720 3150214 - molecular chaperone gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14555 AFK63_RS14560 AFK63_14580 AFK63_RS14560 3150337 3152751 - outer membrane protein biogenesis protein YaeT part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14560 AFK63_RS14565 AFK63_14585 AFK63_RS14565 3152782 3154134 - zinc metallopeptidase RseP catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14565 AFK63_RS14570 AFK63_14590 cdsA cdsA 3154146 3155003 - CDP-diglyceride synthetase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14570 AFK63_RS14575 AFK63_14595 AFK63_RS14575 3155016 3155774 - UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14575 AFK63_RS14580 AFK63_14600 AFK63_RS14580 3155963 3157159 - 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14580 AFK63_RS14585 AFK63_14605 frr frr 3157284 3157841 - ribosome recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14585 AFK63_RS14590 AFK63_14610 AFK63_RS14590 3158010 3158735 - uridylate kinase gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14590 AFK63_RS14595 AFK63_14615 tsf tsf 3158882 3159733 - elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14595 AFK63_RS14600 AFK63_14620 AFK63_RS14600 3159890 3160615 - 30S ribosomal protein S2 gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14600 AFK63_RS14605 AFK63_14625 AFK63_RS14605 3160925 3161719 + methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14605 AFK63_RS14610 AFK63_14630 AFK63_RS14610 3161762 3164437 + (protein-PII) uridylyltransferase catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14610 AFK63_RS14615 AFK63_14635 dapD dapD 3164480 3165304 + 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-carboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14615 AFK63_RS14620 AFK63_14640 AFK63_RS14620 3165414 3165803 + hypothetical protein gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14620 AFK63_RS14625 AFK63_14645 AFK63_RS14625 3165871 3167298 - serine endoprotease protease Do%3B required at high temperature%3B degrades damaged proteins gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14625 AFK63_RS14630 AFK63_14650 dgt dgt 3167441 3168955 - deoxyguanosinetriphosphate triphosphohydrolase forms a homotetramer%3B requires magnesium for activity%3B catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14630 AFK63_RS14635 AFK63_14655 AFK63_RS14635 3169050 3169748 + 5'-methylthioadenosine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14635 AFK63_RS14640 AFK63_14660 AFK63_RS14640 3169741 3170541 + vitamin B12-transporter protein BtuF solute binding component of the vitamin B12 transport system BtuCDF gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14640 AFK63_RS14645 AFK63_14665 AFK63_RS14645 3170558 3171178 + hypothetical protein gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14645 AFK63_RS14650 AFK63_14670 AFK63_RS14650 3171231 3171575 - iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14650 AFK63_RS14655 AFK63_14675 AFK63_RS14655 3171657 3173060 - H+/Cl- exchange transporter ClcA gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14655 AFK63_RS14660 AFK63_14680 AFK63_RS14660 3173233 3174513 + glutamate-1-semialdehyde aminotransferase Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14660 AFK63_RS14665 AFK63_14685 AFK63_RS14665 3174620 3176605 - iron-hydroxamate transporter permease subunit part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14665 AFK63_RS14670 AFK63_14690 AFK63_RS14670 3176602 3177498 - iron-hydroxamate transporter substrate-binding subunit Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter%3B binds to all hydroxamate siderophores gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14670 AFK63_RS14675 AFK63_14695 AFK63_RS14675 3177498 3178295 - iron-hydroxamate transporter ATP-binding subunit part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14675 AFK63_RS14680 AFK63_14700 AFK63_RS14680 3178342 3180579 - ferrichrome transporter involved with the transport of ferrichrome across the outer membrane%3B binds the ferrichrome-iron ligand and interacts with the TonB protein gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14680 AFK63_RS14685 AFK63_14705 mrcB mrcB 3180854 3183382 - bifunctional glycosyl transferase/transpeptidase penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14685 AFK63_RS14690 AFK63_14710 AFK63_RS14690 3183486 3185915 - ATP-dependent helicase HrpB similar in sequence to the ATP-dependent RNA helicase HrpA gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14690 AFK63_RS14695 AFK63_14715 AFK63_RS14695 3185987 3186517 + 2'-5' RNA ligase gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14695 AFK63_RS14700 AFK63_14720 AFK63_RS14700 3186527 3187231 + transcriptional regulator gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14700 AFK63_RS14705 AFK63_14725 dksA dksA 3187410 3187865 + RNA polymerase-binding transcription factor DksA gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14705 AFK63_RS14710 AFK63_14730 AFK63_RS14710 3187935 3188831 + glutamyl-Q tRNA(Asp) ligase this tRNA synthetase lacks the tRNA anticodon interaction domain%3B instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4%2C5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp%3B the modified tRNA does not bind elongation factor Tu gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14710 AFK63_RS14715 AFK63_14735 pcnB pcnB 3188938 3190281 + poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14715 AFK63_RS14720 AFK63_14740 AFK63_RS14720 3190278 3190757 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine and ATP gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14720 AFK63_RS14725 AFK63_14745 panB panB 3190845 3191639 + 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14725 AFK63_RS14730 AFK63_14750 panC panC 3191652 3192506 + pantoate--beta-alanine ligase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14730 AFK63_RS14735 AFK63_14755 AFK63_RS14735 3192604 3192984 + aspartate 1-decarboxylase gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14735 AFK63_RS14740 AFK63_14760 AFK63_RS14740 3193028 3194275 - hypothetical protein gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14740 AFK63_RS14745 AFK63_14765 AFK63_RS14745 3194355 3194786 - PTS sugar transporter subunit IIA gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14745 AFK63_RS14750 AFK63_14770 AFK63_RS14750 3194874 3195644 - ABC transporter permease gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14750 AFK63_RS14755 AFK63_14775 AFK63_RS14755 3195641 3196567 - multidrug ABC transporter ATP-binding protein gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14755 AFK63_RS14760 AFK63_14780 AFK63_RS14760 3196676 3197338 + carbonic anhydrase catalyzes the interconversion of bicarbonate and carbon dioxide gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14760 AFK63_RS14765 AFK63_14785 AFK63_RS14765 3197393 3197929 - hypoxanthine phosphoribosyltransferase catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14765 AFK63_RS14770 AFK63_14790 AFK63_RS14770 3198122 3200518 + glucose dehydrogenase quinoprotein glucose dehydrogenase%3B catalyzes the formation of D-glucono-1%2C5-lactone from D-glucose and ubiquinone gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14770 AFK63_RS14775 AFK63_14795 AFK63_RS14775 3200658 3202220 - multicopper oxidase laccase%3B copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14775 AFK63_RS14780 AFK63_14800 AFK63_RS14780 3202881 3203435 - CRISPR-associated protein Csy4 gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14780 AFK63_RS14785 AFK63_14805 AFK63_RS14785 3203445 3204443 - CRISPR-associated protein Cas5 gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14785 AFK63_RS14790 AFK63_14810 AFK63_RS14790 3204458 3205414 - CRISPR type I-F system protein Csy2 gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14790 AFK63_RS14795 AFK63_14815 AFK63_RS14795 3205411 3206724 - CRISPR type I-F system protein Csy1 gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14795 AFK63_RS14800 AFK63_14820 AFK63_RS14800 3206741 3210004 - CRISPR-associated protein Cas3 gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14800 AFK63_RS14805 AFK63_14825 AFK63_RS14805 3210001 3210984 - subtype I-F CRISPR-associated endonuclease Cas1 gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14805 AFK63_RS14810 AFK63_14830 AFK63_RS14810 3214335 3214682 + hypothetical protein gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14810 AFK63_RS14815 AFK63_14835 AFK63_RS14815 3214792 3215658 + spermidine synthase gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14815 AFK63_RS14820 AFK63_14840 AFK63_RS14820 3215673 3216467 + S-adenosylmethionine decarboxylase S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14820 AFK63_RS14825 AFK63_14845 AFK63_RS14825 3216495 3216860 - hypothetical protein gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14825 AFK63_RS14830 AFK63_14850 AFK63_RS14830 3217045 3217431 + hypothetical protein gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14830 AFK63_RS14835 AFK63_14855 AFK63_RS14835 3217516 3220035 - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14835 AFK63_RS14840 AFK63_14860 AFK63_RS14840 3220924 3222348 - dihydrolipoamide dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14840 AFK63_RS14845 AFK63_14865 aceF aceF 3222556 3224457 - pyruvate dehydrogenase E2 component of pyruvate dehydrogenase multienzyme complex%3B in Escherichia coli AceF contains three N-terminal lipoyl domains gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14845 AFK63_RS14850 AFK63_14870 aceE aceE 3224472 3227135 - pyruvate dehydrogenase E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14850 AFK63_RS14855 AFK63_14875 pdhR pdhR 3227390 3228154 - PdhR family transcriptional regulator activates lctPRD operon%3B autoregulates itself through repression of pdhR-aceEF-lpdA operon%3B regulates pyruvate dehydrogenase complex gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14855 AFK63_RS14860 AFK63_14880 AFK63_RS14860 3228696 3230066 + amino acid permease gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14860 AFK63_RS14865 AFK63_14885 AFK63_RS14865 3230223 3231623 + permease gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14865 AFK63_RS14870 AFK63_14890 AFK63_RS14870 3231633 3232586 + alpha-N-arabinofuranosidase gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14870 AFK63_RS14875 AFK63_14895 AFK63_RS14875 3232605 3233459 - regulatory protein AmpE involved in regulation of beta-lactamase%3B putative signaling protein gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14875 AFK63_RS14880 AFK63_14900 AFK63_RS14880 3233456 3234019 - N-acetyl-anhydromuranmyl-L-alanine amidase gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14880 AFK63_RS14885 AFK63_14905 AFK63_RS14885 3234107 3234997 + nicotinate-nucleotide pyrophosphorylase catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14885 AFK63_RS14890 AFK63_14910 AFK63_RS14890 3235262 3235696 + major pilin subunit gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14890 AFK63_RS14895 AFK63_14915 AFK63_RS14895 3235711 3237093 + hypothetical protein gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14895 AFK63_RS14900 AFK63_14920 AFK63_RS14900 3237086 3238285 + type IV pilin biogenesis protein gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14900 AFK63_RS14905 AFK63_14925 AFK63_RS14905 3238324 3239367 - GMP reductase catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14905 AFK63_RS14910 AFK63_14930 coaE coaE 3239633 3240253 + dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14910 AFK63_RS14915 AFK63_14935 AFK63_RS14915 3240253 3240996 + hypothetical protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14915 AFK63_RS14920 AFK63_14940 AFK63_RS14920 3241006 3241206 + zinc-binding protein inhibits supercoiling by DNA gyrase by binding to the GyrB subunit gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14920 AFK63_RS14925 AFK63_14945 AFK63_RS14925 3241203 3241598 - nucleoside triphosphate hydrolase gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14925 AFK63_RS14930 AFK63_14950 secA secA 3241658 3244363 - preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14930 AFK63_RS14935 AFK63_14955 AFK63_RS14935 3244422 3244856 - secretion protein gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14935 AFK63_RS14940 AFK63_14960 lpxC lpxC 3245214 3246131 - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14940 AFK63_RS14945 AFK63_14965 AFK63_RS14945 3246233 3247384 - cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14945 AFK63_RS14950 AFK63_14970 ftsA ftsA 3247448 3248704 - cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14950 AFK63_RS14955 AFK63_14975 AFK63_RS14955 3248701 3249531 - cell division protein FtsQ involved in septum formation gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14955 AFK63_RS14960 AFK63_14980 ddl ddl 3249533 3250453 - D-alanine--D-alanine ligase D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14960 AFK63_RS14965 AFK63_14985 AFK63_RS14965 3250446 3251912 - UDP-N-acetylmuramate--L-alanine ligase gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14965 AFK63_RS14970 AFK63_14990 murG murG 3251981 3253048 - UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14970 AFK63_RS14975 AFK63_14995 AFK63_RS14975 3253045 3254289 - flippase gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14975 AFK63_RS14980 AFK63_15000 murD murD 3254289 3255605 - UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14980 AFK63_RS14985 AFK63_15005 mraY mraY 3255608 3256690 - phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14985 AFK63_RS14990 AFK63_15010 murF murF 3256684 3258042 - UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14990 AFK63_RS14995 AFK63_15015 murE murE 3258039 3259526 - UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS14995 AFK63_RS15000 AFK63_15020 AFK63_RS15000 3259513 3261276 - cell division protein FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15000 AFK63_RS15005 AFK63_15025 AFK63_RS15005 3261292 3261657 - cell division protein FtsL membrane bound cell division protein at septum containing leucine zipper motif gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15005 AFK63_RS15010 AFK63_15030 AFK63_RS15010 3261654 3262595 - 16S rRNA (cytosine(1402)-N(4))-methyltransferase gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15010 AFK63_RS15015 AFK63_15035 AFK63_RS15015 3262599 3263057 - cell division protein MraZ MraZ%3B UPF0040%3B crystal structure shows similarity to AbrB gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15015 AFK63_RS15020 AFK63_15040 AFK63_RS15020 3263637 3264641 - transcriptional regulator binds D-fructose as an inducer%3B involved in regulation of operons for central pathways of carbon metabolism gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15020 AFK63_RS15025 AFK63_15045 ilvH ilvH 3264821 3265312 - acetolactate synthase with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15025 AFK63_RS15030 AFK63_15050 AFK63_RS15030 3265315 3267039 - acetolactate synthase 3 catalytic subunit catalyzes the formation of 2-acetolactate from pyruvate%2C leucine sensitive gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15030 AFK63_RS15035 AFK63_15055 leuO leuO 3267440 3268384 - transcriptional regulator activator for leuABCD operon%3B member of LysR family of transcriptional activators gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15035 AFK63_RS15040 AFK63_15060 AFK63_RS15040 3269185 3270756 + 2-isopropylmalate synthase gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15040 AFK63_RS15045 AFK63_15065 AFK63_RS15045 3270756 3271847 + 3-isopropylmalate dehydrogenase gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15045 AFK63_RS15050 AFK63_15070 AFK63_RS15050 3271850 3273250 + isopropylmalate isomerase dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15050 AFK63_RS15055 AFK63_15075 leuD leuD 3273261 3273866 + isopropylmalate isomerase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15055 AFK63_RS15060 AFK63_15080 AFK63_RS15060 3274006 3275184 - sugar transporter gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15060 AFK63_RS15065 AFK63_15085 AFK63_RS15065 3275555 3277219 + SgrR family transcriptional regulator activates sgrS under glucose-phosphate stress conditions gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15065 AFK63_RS15070 AFK63_15090 tbpA tbpA 3277389 3278372 + thiamine ABC transporter substrate-binding protein part of the thiamine and TPP transport system tbpA-thiPQ gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15070 AFK63_RS15075 AFK63_15095 thiP thiP 3278348 3279958 + thiamine ABC transporter permease permease%3B with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell%3B repressed in presence of exogenous thiamine gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15075 AFK63_RS15080 AFK63_15100 thiQ thiQ 3279942 3280643 + thiamine ABC transporter ATP-binding protein with TbpA and ThiP is part of the thiamine and TPP transport system gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15080 AFK63_RS15085 AFK63_15105 AFK63_RS15085 3280637 3281407 - membrane protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15085 AFK63_RS15090 AFK63_15110 AFK63_RS15090 3281524 3282405 - transcriptional regulator positive and negative regulator%3B regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15090 AFK63_RS15095 AFK63_15115 AFK63_RS15095 3282709 3284421 + ribulokinase catalyzes the phosphorylation of ribulose to ribulose 5-phosphate gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15095 AFK63_RS15100 AFK63_15120 AFK63_RS15100 3284432 3285934 + sugar isomerase catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15100 AFK63_RS15105 AFK63_15125 araD araD 3286018 3286713 + ribulose 5-phosphate epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15105 AFK63_RS15110 AFK63_15130 AFK63_RS15110 3286846 3289206 + DNA polymerase II Has polymerase%2C DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15110 AFK63_RS15115 AFK63_15135 AFK63_RS15115 3289340 3292246 + ATP-dependent helicase transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15115 AFK63_RS15120 AFK63_15140 AFK63_RS15120 3292259 3292915 + 23S rRNA pseudouridylate synthase catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15120 AFK63_RS15125 AFK63_15145 djlA djlA 3293000 3293818 - molecular chaperone DnaJ functions as a co-chaperone with DnaK%3B involved in regulation of colanic acid capsule%3B inner membrane protein%3B dimerized via transmembrane domain%3B J-like domain is cytoplasmic and can functionally substitute for DnaJ%3B stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15125 AFK63_RS15130 AFK63_15150 AFK63_RS15130 3294002 3296365 + LPS biosynthesis protein is involved in outer membrane permeability gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15130 AFK63_RS15135 AFK63_15155 AFK63_RS15135 3296419 3297705 + peptidylprolyl isomerase Chaperone involved in the folding of extracytoplasmic proteins%2C especially OmpA%2C OmpF and LamB gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15135 AFK63_RS15140 AFK63_15160 pdxA pdxA 3297705 3298700 + 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15140 AFK63_RS15145 AFK63_15165 ksgA ksgA 3298697 3299518 + dimethyladenosine transferase in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15145 AFK63_RS15150 AFK63_15170 apaG apaG 3299521 3299898 + heavy metal transporter protein associated with Co2+ and Mg2+ efflux gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15150 AFK63_RS15155 AFK63_15175 apaH apaH 3299903 3300754 + diadenosine tetraphosphatase hydrolyzes P(1)%2CP(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15155 AFK63_RS15160 AFK63_15180 folA folA 3300939 3301418 - dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15160 AFK63_RS15165 AFK63_15185 AFK63_RS15165 3301672 3302286 + lysine transporter LysE gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15165 AFK63_RS15170 AFK63_15190 AFK63_RS15170 3302336 3304198 - potassium transporter KefC transport system that facilitates potassium-efflux gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15170 AFK63_RS15175 AFK63_15195 AFK63_RS15175 3304191 3304721 - potassium transporter KefF Required for full activity of KefC%2C a potassium-proton antiporter gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15175 AFK63_RS15180 AFK63_15200 AFK63_RS15180 3304903 3305136 - lipoprotein gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15180 AFK63_RS15185 AFK63_15205 AFK63_RS15185 3305269 3306132 - hypothetical protein gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15185 AFK63_RS15190 AFK63_15210 carB carB 3306292 3309516 - carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15190 AFK63_RS15195 AFK63_15215 AFK63_RS15195 3309535 3310683 - carbamoyl phosphate synthase small subunit catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15195 AFK63_RS15200 AFK63_15220 AFK63_RS15200 3311150 3311971 - 4-hydroxy-tetrahydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15200 AFK63_RS15205 AFK63_15225 AFK63_RS15205 3312161 3312793 - alanyl-tRNA synthetase gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15205 AFK63_RS15210 AFK63_15230 AFK63_RS15210 3312888 3313793 + transcriptional regulator gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15210 AFK63_RS15215 AFK63_15235 AFK63_RS15215 3313795 3314712 - ribonucleoside hydrolase catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15215 AFK63_RS15220 AFK63_15240 ispH ispH 3314806 3315756 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15220 AFK63_RS15225 AFK63_15245 AFK63_RS15225 3315737 3316207 - peptidyl-prolyl cis-trans isomerase rotamase%3B accelerates isomerization of the peptidyl prolyl bond%2C involved in the folding of proteases gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15225 AFK63_RS15230 AFK63_15250 lspA lspA 3316324 3316824 - lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15230 AFK63_RS15235 AFK63_15255 ileS ileS 3316824 3319640 - isoleucyl-tRNA synthetase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15235 AFK63_RS15240 AFK63_15260 AFK63_RS15240 3319689 3320627 - FMN adenylyltransferase gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15240 AFK63_RS15245 AFK63_15265 rpsT rpsT 3320945 3321208 + 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15245 AFK63_RS15250 AFK63_15270 nhaR nhaR 3321285 3322181 - transcriptional regulator Na+/H+ antiporter regulatory protein%3B activates the genes nhaA and osmC gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15250 AFK63_RS15255 AFK63_15275 nhaA nhaA 3322254 3323426 - pH-dependent sodium/proton antiporter exports sodium by using the electrochemical proton gradient to allow protons into the cell%3B functions in adaptation to high salinity and alkaline pH%3B activity increases at higher pH%3B downregulated at acidic pH gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15255 AFK63_RS15260 AFK63_15280 AFK63_RS15260 3323668 3325770 - chitinase gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15260 AFK63_RS15265 AFK63_15285 AFK63_RS15265 3326174 3326620 + membrane protein gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15265 AFK63_RS15270 AFK63_15290 AFK63_RS15270 3326643 3327182 + hypothetical protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15270 AFK63_RS15275 AFK63_15295 AFK63_RS15275 3327227 3327565 - phage protein gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15275 AFK63_RS15280 AFK63_15300 AFK63_RS15280 3327749 3328696 - hypothetical protein gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15280 AFK63_RS15285 AFK63_15305 AFK63_RS15285 3328957 3330096 - molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15285 AFK63_RS15290 AFK63_15310 dnaK dnaK 3330181 3332097 - molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15290 AFK63_RS15295 AFK63_15315 AFK63_RS15295 3332391 3332957 + hypothetical protein gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15295 AFK63_RS15300 AFK63_15320 AFK63_RS15300 3333122 3334429 - MFS transporter gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15300 AFK63_RS15305 AFK63_15325 mogA mogA 3334557 3335144 - molybdenum cofactor biosynthesis protein MogA forms a trimer%3B related to eukaryotic protein gephyrin%3B functions during molybdenum cofactor biosynthesis gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15305 AFK63_RS15310 AFK63_15330 AFK63_RS15310 3335253 3336206 - transaldolase gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15310 AFK63_RS15315 AFK63_15335 AFK63_RS15315 3336412 3337845 + sodium:alanine symporter gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15315 AFK63_RS15320 AFK63_15340 AFK63_RS15320 3337924 3338697 + hypothetical protein gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15320 AFK63_RS15325 AFK63_15345 AFK63_RS15325 3338728 3338964 - hypothetical protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15325 AFK63_RS15330 AFK63_15350 AFK63_RS15330 3339231 3340520 - threonine synthase gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15330 AFK63_RS15335 AFK63_15355 AFK63_RS15335 3340524 3341453 - homoserine kinase gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15335 AFK63_RS15340 AFK63_15360 thrA thrA 3341455 3343917 - aspartate kinase multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15340 AFK63_RS15345 AFK63_15365 AFK63_RS15345 3344272 3344958 - RNA methyltransferase member of the SPOUT superfamily of methyltransferases gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15345 AFK63_RS15350 AFK63_15370 AFK63_RS15350 3345592 3346308 + two-component system response regulator gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15350 AFK63_RS15355 AFK63_15375 AFK63_RS15355 3346366 3347724 - hypothetical protein gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15355 AFK63_RS15360 AFK63_15380 AFK63_RS15360 3347804 3349228 - two-component system sensor histidine kinase part of a two-component regulatory system with CreB or PhoB%3B involved in catabolic regulation gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15360 AFK63_RS15365 AFK63_15385 AFK63_RS15365 3349228 3349920 - two-component system response regulator response regulator in two-component regulatory system with CreC%3B CreB protein is phosphorylated by sensor protein phospho-CreC%3B involved in catabolic regulation gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15365 AFK63_RS15370 AFK63_15390 AFK63_RS15370 3349939 3350418 - hypothetical protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15370 AFK63_RS15375 AFK63_15395 AFK63_RS15375 3350628 3351497 + transcriptional regulator AraC family%3B binds to the right arm of the replication origin oriC gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15375 AFK63_RS15380 AFK63_15400 AFK63_RS15380 3351494 3352141 - phosphoglycerate mutase catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15380 AFK63_RS15385 AFK63_15405 yjjX yjjX 3352196 3352711 + inositol monophosphatase pyrophosphatase%3B has activity against dUTP and dITP%3B the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226%3B in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms%3B in Escherichia coli overexpression of this gene leads to resistance to an HMP analog gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15385 AFK63_RS15390 AFK63_15410 AFK63_RS15390 3352702 3353031 - transcriptional regulator When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15390 AFK63_RS15395 AFK63_15415 AFK63_RS15395 3353085 3355019 - murein transglycosylase catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15395 AFK63_RS15400 AFK63_15420 AFK63_RS15400 3355254 3356921 + ABC transporter ATP-binding protein ChvD%3B in Agrobacterium tumefaciens%2C mutations in both Walker boxes were found to affect virulence gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15400 AFK63_RS15405 AFK63_15425 AFK63_RS15405 3357425 3358573 + capsule biosynthesis protein gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15405 AFK63_RS15410 AFK63_15430 AFK63_RS15410 3358602 3360266 + polysialic acid transporter gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15410 AFK63_RS15415 AFK63_15435 AFK63_RS15415 3360269 3362296 + capsule biosynthesis protein gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15415 AFK63_RS15420 AFK63_15440 AFK63_RS15420 3362313 3363509 + capsular biosynthesis protein gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15420 AFK63_RS15425 AFK63_15445 AFK63_RS15425 3363504 3364733 - hypothetical protein gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15425 AFK63_RS15430 AFK63_15450 AFK63_RS15430 3364793 3368581 - beta-1%2C3-glucosyltransferase gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15430 AFK63_RS15435 AFK63_15455 AFK63_RS15435 3368574 3369686 - capsule biosynthesis protein CapC gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15435 AFK63_RS15440 AFK63_15460 AFK63_RS15440 3369689 3370354 - ABC transporter ATP-binding protein gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15440 AFK63_RS15445 AFK63_15465 AFK63_RS15445 3370351 3371127 - polysialic acid transporter gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15445 AFK63_RS15450 AFK63_15470 AFK63_RS15450 3371465 3372370 - LysR family transcriptional regulator gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15450 AFK63_RS15455 AFK63_15475 AFK63_RS15455 3372491 3373492 + NADPH:quinone reductase gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15455 AFK63_RS15460 AFK63_15480 AFK63_RS15460 3373634 3374866 - transcriptional regulator catalyzes the formation of NAD(+) from nicotinamide ribonucleotide%3B catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside%3B also has a regulatory function gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15460 AFK63_RS15465 AFK63_15485 AFK63_RS15465 3375024 3376406 - DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15465 AFK63_RS15470 AFK63_15490 serB serB 3376418 3377389 - phosphoserine phosphatase catalyzes the formation of serine from O-phosphoserine gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15470 AFK63_RS15475 AFK63_15495 AFK63_RS15475 3377496 3378158 + hypothetical protein gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15475 AFK63_RS15480 AFK63_15500 lplA lplA 3378206 3379222 + lipoate--protein ligase Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15480 AFK63_RS15485 AFK63_15505 deoD deoD 3379441 3380160 - purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15485 AFK63_RS15490 AFK63_15510 AFK63_RS15490 3380287 3381510 - phosphopentomutase gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15490 AFK63_RS15495 AFK63_15515 AFK63_RS15495 3381563 3382885 - thymidine phosphorylase gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15495 AFK63_RS15500 AFK63_15520 AFK63_RS15500 3382989 3383768 - deoxyribose-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15500 AFK63_RS15505 AFK63_15525 AFK63_RS15505 3384105 3385382 - nucleoside transporter NupC gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15505 AFK63_RS15510 AFK63_15530 AFK63_RS15510 3385507 3386292 - deoxyribonuclease YjjV gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15510 AFK63_RS15515 AFK63_15535 AFK63_RS15515 3386289 3387428 - hypothetical protein gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15515 AFK63_RS15520 AFK63_15540 AFK63_RS15520 3387832 3388446 - periplasmic protein gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15520 AFK63_RS15525 AFK63_15545 prfC prfC 3388858 3390447 - peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15525 AFK63_RS15530 AFK63_15550 AFK63_RS15530 3390541 3391218 - dUMP phosphatase manganese-dependent 5'-nucleotidase%3B specific for 5'-UMP%2C 5'-dUMP%2C and 5'-dTMP%3B member of haloacid dehalogenase (HAD)-like hydrolase superfamily gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15530 AFK63_RS15535 AFK63_15555 rimI rimI 3391239 3391682 - ribosomal-protein-alanine acetyltransferase alanine acetyltransferase that specifically acetylates ribosomal protein S18 gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15535 AFK63_RS15540 AFK63_15560 AFK63_RS15540 3391651 3392061 - DNA polymerase III subunit psi with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15540 AFK63_RS15545 AFK63_15565 rsmC rsmC 3392167 3393195 + 16S rRNA methyltransferase 16S rRNA M2G1207 methyltransferase%3B one of many enzymes that modify bases of the ribosomal RNA%3B this enzyme methylates the G at position 1207 of the small ribosomal subunit gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15545 AFK63_RS15550 AFK63_15570 AFK63_RS15550 3393326 3393411 + tRNA-Leu tRNA gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15550 AFK63_RS15555 AFK63_15575 AFK63_RS15555 3393444 3393529 + tRNA-Leu tRNA gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15555 AFK63_RS15560 AFK63_15580 AFK63_RS15560 3393560 3393645 + tRNA-Leu tRNA gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15560 AFK63_RS15565 AFK63_15585 AFK63_RS15565 3393731 3394012 - membrane protein gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15565 AFK63_RS15570 AFK63_15590 AFK63_RS15570 3394216 3395277 + membrane protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15570 AFK63_RS15575 AFK63_15595 AFK63_RS15575 3395394 3396182 + iron reductase gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15575 AFK63_RS15580 AFK63_15600 AFK63_RS15580 3396213 3397559 - cytochrome C biogenesis protein CcmF gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15580 AFK63_RS15585 AFK63_15605 AFK63_RS15585 3397956 3398414 + prolyl-tRNA synthetase gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15585 AFK63_RS15590 AFK63_15610 AFK63_RS15590 3398488 3399141 - transcriptional regulator regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15590 AFK63_RS15595 AFK63_15615 AFK63_RS15595 3399105 3399746 - LuxR family transcriptional regulator gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15595 AFK63_RS15600 AFK63_15620 AFK63_RS15600 3400343 3401119 + membrane protein gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15600 AFK63_RS15605 AFK63_15625 AFK63_RS15605 3401110 3401583 + hypothetical protein gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15605 AFK63_RS15610 AFK63_15630 AFK63_RS15610 3401654 3402109 + MarR family transcriptional regulator gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15610 AFK63_RS15615 AFK63_15635 AFK63_RS15615 3402189 3402617 + organic hydroperoxide resistance protein gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15615 AFK63_RS15620 AFK63_15640 AFK63_RS15620 3402839 3403384 + primosomal protein DnaI gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15620 AFK63_RS15625 AFK63_15645 AFK63_RS15625 3403387 3404124 + DNA replication protein DnaC acts to load the DnaB helicase onto the initiation site during DNA replication gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15625 AFK63_RS15630 AFK63_15650 AFK63_RS15630 3404482 3406773 + phosphoglycerol transferase I catalyzes the transfer of phosphoglycerol to the glucan backbone gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15630 AFK63_RS15635 AFK63_15655 AFK63_RS15635 3406783 3407742 - diguanylate cyclase gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15635 AFK63_RS15640 AFK63_15660 AFK63_RS15640 3407918 3409705 - DeoR family transcriptional regulator gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15640 AFK63_RS15645 AFK63_15665 AFK63_RS15645 3409931 3411598 - chemotaxis protein serine sensor receptor gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15645 AFK63_RS15650 AFK63_15670 AFK63_RS15650 3411895 3413094 - hypothetical protein gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15650 AFK63_RS15655 AFK63_15675 AFK63_RS15655 3413244 3416291 - serine protease gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15655 AFK63_RS15660 AFK63_15680 AFK63_RS15660 3416941 3418176 - cytosine deaminase Catalyzes the deamination of cytosine to uracil and ammonia gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15660 AFK63_RS15665 AFK63_15685 AFK63_RS15665 3418173 3419402 - Fis family transcriptional regulator gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15665 AFK63_RS15670 AFK63_15690 AFK63_RS15670 3419399 3420667 - cytosine permease gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15670 AFK63_RS15675 AFK63_15695 AFK63_RS15675 3420904 3422334 - 6-phospho-beta-glucosidase gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15675 AFK63_RS15680 AFK63_15700 AFK63_RS15680 3422348 3423811 - PTS cellobiose/arbutin/salicin transporter subunits IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15680 AFK63_RS15685 AFK63_15705 AFK63_RS15685 3424122 3425144 + transcriptional regulator gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15685 AFK63_RS15690 AFK63_15710 AFK63_RS15690 3425191 3426261 - 1%2C4-alpha-glucan-branching protein gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15690 AFK63_RS15695 AFK63_15715 AFK63_RS15695 3426251 3427318 - hemolysin secretion protein D gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15695 AFK63_RS15700 AFK63_15720 AFK63_RS15700 3427321 3427791 - MarR family transcriptional regulator gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15700 AFK63_RS15705 AFK63_15725 lacI lacI 3427929 3429002 - lac repressor transcriptional repressor of lac operon%3B forms a homotetramer as a dimer of dimers%3B binds specific sites in lac operon resulting in DNA looping between the operators%3B binds allolactose as inducer gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15705 AFK63_RS15710 AFK63_15730 AFK63_RS15710 3429275 3430543 + maltoporin porin involved in the transport of maltose and maltodextrins gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15710 AFK63_RS15715 AFK63_15735 AFK63_RS15715 3430751 3431068 - PTS sugar transporter gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15715 AFK63_RS15720 AFK63_15740 AFK63_RS15720 3431138 3433198 - beta-galactosidase gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15720 AFK63_RS15725 AFK63_15745 AFK63_RS15725 3433296 3434495 - galactosidase gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15725 AFK63_RS15730 AFK63_15750 AFK63_RS15730 3434500 3435351 - arabinogalactan oligomer ABC transporter permease gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15730 AFK63_RS15735 AFK63_15755 AFK63_RS15735 3435361 3436668 - arabinogalactan ABC transporter permease gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15735 AFK63_RS15740 AFK63_15760 AFK63_RS15740 3436754 3437989 - cyclodextrin-binding protein gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15740 AFK63_RS15745 AFK63_15765 AFK63_RS15745 3438349 3439458 + sugar ABC transporter ATP-binding protein gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15745 AFK63_RS15750 AFK63_15770 AFK63_RS15750 3439605 3439976 + endoribonuclease gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15750 AFK63_RS15755 AFK63_15775 AFK63_RS15755 3440346 3441764 + GntR family transcriptional regulator gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15755 AFK63_RS15760 AFK63_15780 AFK63_RS15760 3441817 3443082 + membrane protein gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15760 AFK63_RS15765 AFK63_15785 AFK63_RS15765 3443089 3443583 - hypothetical protein gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15765 AFK63_RS15770 AFK63_15790 AFK63_RS15770 3444224 3445264 + hypothetical protein gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15770 AFK63_RS15775 AFK63_15795 AFK63_RS15775 3445258 3445515 + hypothetical protein gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15775 AFK63_RS15780 AFK63_15800 gldA gldA 3446256 3447359 + glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15780 AFK63_RS15785 AFK63_15805 AFK63_RS15785 3447427 3447789 - hypothetical protein gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15785 AFK63_RS15790 AFK63_15810 AFK63_RS15790 3447999 3448325 - acyl carrier protein gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15790 AFK63_RS15795 AFK63_15815 AFK63_RS15795 3448584 3449006 - hypothetical protein gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15795 AFK63_RS15800 AFK63_15820 AFK63_RS15800 3448993 3449496 - type IV secretion protein Rhs gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15800 AFK63_RS15805 AFK63_15825 AFK63_RS15805 3450138 3450222 - tRNA-Leu tRNA gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15805 AFK63_RS15810 AFK63_15830 AFK63_RS15810 3450483 3451499 + HNH endonuclease gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15810 AFK63_RS15815 AFK63_15835 AFK63_RS15815 3451499 3452077 + tellurite resistance protein gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15815 AFK63_RS15820 AFK63_15840 AFK63_RS15820 3452428 3453030 + transcriptional regulator gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15820 AFK63_RS15825 AFK63_15845 AFK63_RS15825 3453119 3453625 - hypothetical protein gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15825 AFK63_RS15830 AFK63_15850 AFK63_RS15830 3453780 3454163 - hypothetical protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15830 AFK63_RS15835 AFK63_15855 AFK63_RS15835 3454163 3454582 - hypothetical protein gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15835 AFK63_RS15840 AFK63_15860 AFK63_RS15840 3454634 3455116 - ribonuclease gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15840 AFK63_RS15845 AFK63_15865 AFK63_RS15845 3455140 3455592 - muraminidase gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15845 AFK63_RS15850 AFK63_15870 AFK63_RS15850 3455585 3456310 - hypothetical protein gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15850 AFK63_RS15855 AFK63_15875 AFK63_RS15855 3456360 3457028 - hypothetical protein gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15855 AFK63_RS15860 AFK63_15880 AFK63_RS15860 3457281 3458300 + alcohol dehydrogenase gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15860 AFK63_RS15865 AFK63_15885 AFK63_RS15865 3458416 3459033 - hypothetical protein gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15865 AFK63_RS15870 AFK63_15890 AFK63_RS15870 3459053 3459757 - hypothetical protein gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15870 AFK63_RS15875 AFK63_15895 AFK63_RS15875 3459797 3461461 - hypothetical protein gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15875 AFK63_RS15880 AFK63_15900 AFK63_RS15880 3461779 3463416 - dihydroxyacetone kinase gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15880 AFK63_RS15885 AFK63_15905 AFK63_RS15885 3463477 3463944 - hypothetical protein gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15885 AFK63_RS15890 AFK63_15910 AFK63_RS15890 3464012 3465094 - LPS export ABC transporter permease LptG with LptABCF is involved in the transport of lipopolysaccharides gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15890 AFK63_RS15895 AFK63_15915 AFK63_RS15895 3465081 3466193 - LPS export ABC transporter permease LptF with LptBGC is involved in lipopolysaccharide export gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15895 AFK63_RS15900 AFK63_15920 AFK63_RS15900 3466463 3467974 + multifunctional aminopeptidase A catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15900 AFK63_RS15905 AFK63_15925 AFK63_RS15905 3468204 3468665 + DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15905 AFK63_RS15910 AFK63_15930 AFK63_RS15910 3468668 3471523 + valine--tRNA ligase gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15910 AFK63_RS15915 AFK63_15935 AFK63_RS15915 3471717 3472919 - hypothetical protein gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15915 AFK63_RS15920 AFK63_15940 AFK63_RS15920 3473115 3473618 + acetyltransferase gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15920 AFK63_RS15925 AFK63_15945 AFK63_RS15925 3473658 3474467 - hypothetical protein gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15925 AFK63_RS15930 AFK63_15950 AFK63_RS15930 3474512 3475276 - tRNA hydroxylase gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15930 AFK63_RS15935 AFK63_15955 AFK63_RS15935 3475324 3475740 - RNase E inhibitor protein gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15935 AFK63_RS15940 AFK63_15960 AFK63_RS15940 3475904 3476908 + ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15940 AFK63_RS15945 AFK63_15965 AFK63_RS15945 3477050 3477502 - toxin-antitoxin biofilm protein TabA gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15945 AFK63_RS15950 AFK63_15970 AFK63_RS15950 3478173 3479393 + arginine deiminase catalyzes the degradation of arginine to citruline and ammonia gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15950 AFK63_RS15955 AFK63_15975 AFK63_RS15955 3479404 3480315 + carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15955 AFK63_RS15960 AFK63_15980 AFK63_RS15960 3480353 3481357 + ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15960 AFK63_RS15965 AFK63_15985 AFK63_RS15965 3481405 3482808 + C4-dicarboxylate ABC transporter gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15965 AFK63_RS15970 AFK63_15990 AFK63_RS15970 3482978 3483457 + ArgR family transcriptional regulator gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15970 AFK63_RS15975 AFK63_15995 AFK63_RS15975 3483712 3484647 + aspartate carbamoyltransferase catalytic subunit gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15975 AFK63_RS15980 AFK63_16000 AFK63_RS15980 3484658 3485119 + aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15980 AFK63_RS15985 AFK63_16005 AFK63_RS15985 3485193 3485579 + reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15985 AFK63_RS15990 AFK63_16010 AFK63_RS15990 3485633 3487786 - radical SAM protein gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15990 AFK63_RS15995 AFK63_16015 AFK63_RS15995 3487909 3488673 - FMN reductase gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS15995 AFK63_RS16000 AFK63_16020 AFK63_RS16000 3488914 3489447 + PadR family transcriptional regulator gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16000 AFK63_RS16005 AFK63_16025 AFK63_RS16005 3489484 3491031 - chemotaxis protein gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16005 AFK63_RS16010 AFK63_16030 AFK63_RS16010 3491476 3492999 - aerotaxis receptor Aer gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16010 AFK63_RS16015 AFK63_16035 AFK63_RS16015 3493190 3494077 - FOG: GGDEF domain protein gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16015 AFK63_RS16020 AFK63_16040 AFK63_RS16020 3494578 3495885 + putrescine--2-oxoglutarate aminotransferase catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16020 AFK63_RS16025 AFK63_16045 AFK63_RS16025 3495882 3496064 - hypothetical protein gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16025 AFK63_RS16030 AFK63_16050 fadH fadH 3496063 3498081 + 2%2C4-dienoyl-CoA reductase catalyzes the formation of trans-2- enoyl-CoA from 2%2C4-dienoyl-CoA gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16030 AFK63_RS16035 AFK63_16055 AFK63_RS16035 3498888 3500018 - 23S rRNA methyltransferase gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16035 AFK63_RS16040 AFK63_16060 AFK63_RS16040 3500104 3500616 + metal-dependent hydrolase gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16040 AFK63_RS16045 AFK63_16065 AFK63_RS16045 3500643 3501335 + SanA protein gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16045 AFK63_RS16050 AFK63_16070 AFK63_RS16050 3501419 3502417 + oxidoreductase gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16050 AFK63_RS16055 AFK63_16075 AFK63_RS16055 3502709 3503677 + membrane protein gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16055 AFK63_RS16060 AFK63_16080 AFK63_RS16060 3503971 3505218 + serine/threonine protein kinase involved in the import of serine and threonine coupled with the import of sodium gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16060 AFK63_RS16065 AFK63_16085 AFK63_RS16065 3505252 3505794 - membrane protein gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16065 AFK63_RS16070 AFK63_16090 AFK63_RS16070 3505871 3507358 - altronate hydrolase gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16070 AFK63_RS16075 AFK63_16095 AFK63_RS16075 3507376 3508788 - glucuronate isomerase catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate%3B functions in glucuronic and galacturonic metabolism gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16075 AFK63_RS16080 AFK63_16100 AFK63_RS16080 3509261 3510562 + hexuronate transporter involved in the transport of aldohexuronates gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16080 AFK63_RS16085 AFK63_16105 AFK63_RS16085 3510676 3511455 + transcriptional regulator regulates the expression of uxuBA gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16085 AFK63_RS16090 AFK63_16110 AFK63_RS16090 3511771 3512433 + membrane protein gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16090 AFK63_RS16095 AFK63_16115 AFK63_RS16095 3512437 3512820 + Modulator protein MzrA gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16095 AFK63_RS16100 AFK63_16120 AFK63_RS16100 3512973 3513341 + hypothetical protein gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16100 AFK63_RS16105 AFK63_16125 AFK63_RS16105 3513377 3513679 + hypothetical protein gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16105 AFK63_RS16110 AFK63_16130 AFK63_RS16110 3513682 3514080 + membrane protein gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16110 AFK63_RS16115 AFK63_16135 AFK63_RS16115 3514077 3514373 + membrane protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16115 AFK63_RS16120 AFK63_16140 AFK63_RS16120 3514586 3514978 + membrane protein gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16120 AFK63_RS16125 AFK63_16145 AFK63_RS16125 3515053 3516039 + glutathionyl-hydroquinone reductase YqjG gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16125 AFK63_RS16130 AFK63_16150 AFK63_RS16130 3516196 3516561 + membrane protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16130 AFK63_RS16135 AFK63_16155 AFK63_RS16135 3516694 3517617 + fructokinase gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16135 AFK63_RS16140 AFK63_16160 AFK63_RS16140 3517784 3519301 + porin gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16140 AFK63_RS16145 AFK63_16165 AFK63_RS16145 3519373 3520743 + PTS sucrose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16145 AFK63_RS16150 AFK63_16170 AFK63_RS16150 3520743 3522152 + glycosyl hydrolase family 32 gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16150 AFK63_RS16155 AFK63_16175 AFK63_RS16155 3522181 3523194 + sucrose operon repressor gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16155 AFK63_RS16160 AFK63_16180 AFK63_RS16160 3523191 3524090 - LysR family transcriptional regulator gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16160 AFK63_RS16165 AFK63_16185 AFK63_RS16165 3524193 3524894 + hypothetical protein gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16165 AFK63_RS16170 AFK63_16190 AFK63_RS16170 3525626 3525946 + hypothetical protein gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16170 AFK63_RS16175 AFK63_16195 kbaY kbaY 3527019 3527873 + tagatose-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16175 AFK63_RS16180 AFK63_16200 AFK63_RS16180 3528029 3529300 + tagatose-bisphosphate aldolase with KbaY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate%3B subunit Z may act as a chaperone for the Y subunit gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16180 AFK63_RS16185 AFK63_16205 AFK63_RS16185 3529314 3529781 + PTS galactitol transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16185 AFK63_RS16190 AFK63_16210 AFK63_RS16190 3529808 3530092 + PTS galactitol transporter subunit IIB phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16190 AFK63_RS16195 AFK63_16215 AFK63_RS16195 3530097 3531470 + PTS galactitol transporter subunit IIC gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16195 AFK63_RS16200 AFK63_16220 AFK63_RS16200 3531513 3532556 + galactitol-1-phosphate 5-dehydrogenase Zn-dependent%3B NAD(P)-binding%3B catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16200 AFK63_RS16205 AFK63_16225 AFK63_RS16205 3532667 3533440 + galactitol utilization operon repressor gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16205 AFK63_RS16210 AFK63_16230 AFK63_RS16210 3533501 3534361 - 16S rRNA (cytidine(1402)-2'-O)-methyltransferase gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16210 AFK63_RS16215 AFK63_16235 AFK63_RS16215 3534424 3536487 + penicillin-binding protein gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16215 AFK63_RS16220 AFK63_16240 AFK63_RS16220 3536445 3536840 + hypothetical protein gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16220 AFK63_RS16225 AFK63_16245 AFK63_RS16225 3536867 3537457 + phosphoheptose isomerase Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16225 AFK63_RS16230 AFK63_16250 AFK63_RS16230 3537467 3538042 + hypothetical protein gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16230 AFK63_RS16235 AFK63_16255 AFK63_RS16235 3538217 3539257 - membrane protein gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16235 AFK63_RS16240 AFK63_16260 AFK63_RS16240 3539334 3539984 - oxidoreductase gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16240 AFK63_RS16245 AFK63_16265 AFK63_RS16245 3540129 3540647 + general stress protein gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16245 AFK63_RS16250 AFK63_16270 AFK63_RS16250 3540627 3541061 - hypothetical protein gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16250 AFK63_RS16255 AFK63_16275 AFK63_RS16255 3541127 3541414 + hypothetical protein gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16255 AFK63_RS16260 AFK63_16280 AFK63_RS16260 3541417 3541920 - acetyltransferase gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16260 AFK63_RS16265 AFK63_16285 AFK63_RS16265 3541914 3542438 - hypothetical protein gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16265 AFK63_RS16270 AFK63_16290 AFK63_RS16270 3542685 3543680 + protease gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16270 AFK63_RS16275 AFK63_16295 AFK63_RS16275 3543691 3544569 + protease gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16275 AFK63_RS16280 AFK63_16300 AFK63_RS16280 3544722 3545735 + hypothetical protein gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16280 AFK63_RS16285 AFK63_16305 AFK63_RS16285 3545779 3547023 - tryptophan permease tryptophan transporter of high affinity gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16285 AFK63_RS16290 AFK63_16310 tnaA tnaA 3547233 3548621 - tryptophanase tryptophan indole-lyase%3B catalyzes the formation of indole and pyruvate from tryptophan%3B also has xysteine desulfhydrase activity gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16290 AFK63_RS16295 AFK63_16315 AFK63_RS16295 3549015 3550925 - DEAD/DEAH box helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16295 AFK63_RS16300 AFK63_16320 AFK63_RS16300 3551107 3551991 - lipoprotein NlpI lipoprotein that appears to be involved in cell division%3B interacts with the periplasmic protease Prc and may be activated by protease processing gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16300 AFK63_RS16305 AFK63_16325 AFK63_RS16305 3552108 3554243 - polynucleotide phosphorylase/polyadenylase gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16305 AFK63_RS16310 AFK63_16330 AFK63_RS16310 3554488 3554757 - 30S ribosomal protein S15 gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16310 AFK63_RS16315 AFK63_16335 truB truB 3554901 3555845 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16315 AFK63_RS16320 AFK63_16340 rbfA rbfA 3555845 3556246 - ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16320 AFK63_RS16325 AFK63_16345 infB infB 3556380 3559094 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16325 AFK63_RS16330 AFK63_16350 nusA nusA 3559119 3560606 - transcription termination factor NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16330 AFK63_RS16335 AFK63_16355 AFK63_RS16335 3560634 3561086 - clustered with transcription termination protein NusA required for the maturation of the 30S ribosomal subunits gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16335 AFK63_RS16340 AFK63_16360 AFK63_RS16340 3561299 3561375 - tRNA-Met tRNA gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16340 AFK63_RS16345 AFK63_16365 AFK63_RS16345 3561435 3561521 - tRNA-Leu tRNA gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16345 AFK63_RS16350 AFK63_16370 secG secG 3561564 3561896 - preprotein translocase subunit SecG gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16350 AFK63_RS16355 AFK63_16375 glmM glmM 3562120 3563457 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16355 AFK63_RS16360 AFK63_16380 folP folP 3563450 3564298 - dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16360 AFK63_RS16365 AFK63_16385 hflB hflB 3564389 3566323 - ATP-dependent metalloprotease inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16365 AFK63_RS16370 AFK63_16390 rrmJ rrmJ 3566380 3567009 - ribosomal RNA large subunit methyltransferase E Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16370 AFK63_RS16375 AFK63_16395 AFK63_RS16375 3567134 3567427 + RNA-binding protein RNA binding protein found associated to pre-50S subunit of the ribosome%3B putative role in ribosome assembly%3B necessary for optimal growth but not cell viability gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16375 AFK63_RS16380 AFK63_16400 greA greA 3567637 3568113 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16380 AFK63_RS16385 AFK63_16405 AFK63_RS16385 3568361 3569794 + D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16385 AFK63_RS16390 AFK63_16410 AFK63_RS16390 3569797 3570459 + two-component system response regulator gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16390 AFK63_RS16395 AFK63_16415 AFK63_RS16395 3570456 3571517 + two-component system sensor histidine kinase gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16395 AFK63_RS16400 AFK63_16420 obgE obgE 3571578 3572750 - GTPase CgtA ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16400 AFK63_RS16405 AFK63_16425 AFK63_RS16405 3572767 3573732 - membrane protein gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16405 AFK63_RS16410 AFK63_16430 rpmA rpmA 3573827 3574084 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16410 AFK63_RS16415 AFK63_16435 rplU rplU 3574104 3574415 - 50S ribosomal protein L21 gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16415 AFK63_RS16420 AFK63_16440 AFK63_RS16420 3574673 3575644 + octaprenyl diphosphate synthase gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16420 AFK63_RS16425 AFK63_16445 AFK63_RS16425 3575966 3576229 + Ner-like regulatory protein activator of maltose metabolism genes gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16425 AFK63_RS16430 AFK63_16450 AFK63_RS16430 3576375 3577634 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16430 AFK63_RS16435 AFK63_16455 AFK63_RS16435 3577687 3577944 - hypothetical protein gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16435 AFK63_RS16440 AFK63_16460 AFK63_RS16440 3578069 3578371 - phospholipid ABC transporter substrate-binding protein gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16440 AFK63_RS16445 AFK63_16465 AFK63_RS16445 3578371 3579000 - ABC transporter substrate-binding protein involved in maintaining outer membrane lipid asymmetry gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16445 AFK63_RS16450 AFK63_16470 AFK63_RS16450 3579016 3579567 - outer membrane lipid asymmetry maintenance protein MlaD gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16450 AFK63_RS16455 AFK63_16475 AFK63_RS16455 3579571 3580353 - ABC transporter permease gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16455 AFK63_RS16460 AFK63_16480 AFK63_RS16460 3580361 3581176 - ABC transporter ATP-binding protein ABC transporter maintaining outer membrane lipid asymmetry gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16460 AFK63_RS16465 AFK63_16485 AFK63_RS16465 3581410 3582387 + calcium/sodium:proton antiporter YrbG%3B inner membrane protein involved in cell envelope integrity%3B putative sodium ion/calcium ion exchanger%3B in E. coli it is non essential for cell viability%3B member of the YRBG family of cation/Ca2+ exchangers gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16465 AFK63_RS16470 AFK63_16490 AFK63_RS16470 3582403 3583389 + D-arabinose 5-phosphate isomerase gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16470 AFK63_RS16475 AFK63_16495 AFK63_RS16475 3583405 3583971 + 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase forms homotetramers%3B catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate%3B functions in lipopolysaccharide biosynthesis gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16475 AFK63_RS16480 AFK63_16500 AFK63_RS16480 3583968 3584543 + LPS export ABC transporter periplasmic protein LptC gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16480 AFK63_RS16485 AFK63_16505 AFK63_RS16485 3584512 3585069 + LPS transporter LptA%3B periplasmic binding protein part of a putative ABC superfamily of uptake transporters%3B interacts with LptB protein%2C the ATP binding component of the uptake system gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16485 AFK63_RS16490 AFK63_16510 AFK63_RS16490 3585076 3585801 + LPS export ABC transporter ATP-binding protein gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16490 AFK63_RS16495 AFK63_16515 AFK63_RS16495 3585899 3587338 + RNA polymerase sigma-54 factor sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism%3B the rhizobia often have 2 copies of this sigma factor%3B in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation%3B in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions%2C rpoN1 gene was regulated in response to oxygen gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16495 AFK63_RS16500 AFK63_16520 AFK63_RS16500 3587361 3587648 + ribosome hibernation protein YhbH%3B resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase%3B binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization)%3B seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16500 AFK63_RS16505 AFK63_16525 AFK63_RS16505 3587729 3588214 + PTS nitrogen IIA component%2C PtsN involved in nitrogen metabolism%3B protein IIA is phosphorylated by enzyme I(Ntr) gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16505 AFK63_RS16510 AFK63_16530 AFK63_RS16510 3588279 3589133 + glmZ(sRNA)-inactivating NTPase glucosamine-6-phosphate regulated%3B inactivates the glmS upregulator glmZ gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16510 AFK63_RS16515 AFK63_16535 AFK63_RS16515 3589130 3589402 + phosphohistidinoprotein-hexose phosphotransferase gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16515 AFK63_RS16520 AFK63_16540 AFK63_RS16520 3589463 3589894 - hypothetical protein gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16520 AFK63_RS16525 AFK63_16545 AFK63_RS16525 3590198 3590635 - hypothetical protein gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16525 AFK63_RS16530 AFK63_16550 AFK63_RS16530 3590662 3591228 - hypothetical protein gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16530 AFK63_RS16535 AFK63_16555 mtgA mtgA 3591372 3592100 - peptidoglycan transglycosylase glycosyltransferase%3B polymerizes glycan strands in the peptidoglycan gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16535 AFK63_RS16540 AFK63_16560 AFK63_RS16540 3592097 3592750 - isoprenoid biosynthesis protein gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16540 AFK63_RS16545 AFK63_16565 AFK63_RS16545 3592988 3595327 - PAS domain-containing two-component system sensor histidine kinase/response regulator sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon%3B hybrid sensory histidine kinase in two-component regulatory system with ArcA gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16545 AFK63_RS16550 AFK63_16570 AFK63_RS16550 3595439 3596374 - radical SAM protein gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16550 AFK63_RS16555 AFK63_16575 AFK63_RS16555 3596688 3597160 - hypothetical protein gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16555 AFK63_RS16560 AFK63_16580 gltB gltB 3597173 3601519 + glutamate synthase catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16560 AFK63_RS16565 AFK63_16585 AFK63_RS16565 3601533 3602951 + glutamate synthase gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16565 AFK63_RS16570 AFK63_16590 AFK63_RS16570 3603348 3605873 + adhesin gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16570 AFK63_RS16575 AFK63_16595 AFK63_RS16575 3605972 3606463 - Clp protease ClpP gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16575 AFK63_RS16580 AFK63_16600 sspA sspA 3606469 3607110 - stringent starvation protein A transcriptional activator%3B required for activation of bacteriophage P1 late promoter%3B induced by starvation gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16580 AFK63_RS16585 AFK63_16605 AFK63_RS16585 3607422 3607814 - 30S ribosomal protein S9 gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16585 AFK63_RS16590 AFK63_16610 AFK63_RS16590 3607829 3608257 - 50S ribosomal protein L13 gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16590 AFK63_RS16595 AFK63_16615 AFK63_RS16595 3608508 3609638 - hypothetical protein gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16595 AFK63_RS16600 AFK63_16620 AFK63_RS16600 3609842 3610240 + cytochrome d ubiquinol oxidase subunit III (cytochrome bd-I oxidase subunit III) gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16600 AFK63_RS16605 AFK63_16625 AFK63_RS16605 3610415 3611782 + serine endoprotease DegQ gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16605 AFK63_RS16610 AFK63_16630 AFK63_RS16610 3611873 3612940 + serine endoprotease gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16610 AFK63_RS16615 AFK63_16635 AFK63_RS16615 3613001 3613939 - malate dehydrogenase oxidizes malate to oxaloacetate gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16615 AFK63_RS16620 AFK63_16640 AFK63_RS16620 3614374 3614844 + arginine repressor regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16620 AFK63_RS16625 AFK63_16645 AFK63_RS16625 3615209 3615472 + membrane protein gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16625 AFK63_RS16630 AFK63_16650 AFK63_RS16630 3615590 3615856 + membrane protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16630 AFK63_RS16635 AFK63_16655 AFK63_RS16635 3615927 3616199 - hypothetical protein gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16635 AFK63_RS16640 AFK63_16660 gabD gabD 3616245 3617699 - succinate-semialdehyde dehydrogenase catalyzes the formation of succinate from succinate semialdehyde%3B NADP dependent gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16640 AFK63_RS16645 AFK63_16665 AFK63_RS16645 3617783 3619750 - p-hydroxybenzoic acid efflux subunit AaeB with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16645 AFK63_RS16650 AFK63_16670 AFK63_RS16650 3619756 3620688 - p-hydroxybenzoic acid efflux subunit AaeA with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid%2C 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16650 AFK63_RS16655 AFK63_16675 AFK63_RS16655 3620696 3620899 - protein AaeX membrane protein AaeX%3B the gene is a member of the aaeXAB operon gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16655 AFK63_RS16660 AFK63_16680 AFK63_RS16660 3621075 3622019 + transcriptional regulator for aaeXAB operon gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16660 AFK63_RS16665 AFK63_16685 tldD tldD 3622055 3623500 - protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16665 AFK63_RS16670 AFK63_16690 AFK63_RS16670 3623586 3627386 - hypothetical protein gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16670 AFK63_RS16675 AFK63_16695 AFK63_RS16675 3627447 3628916 - ribonuclease G involved in the processing of the 5'end of 16S rRNA gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16675 AFK63_RS16680 AFK63_16700 AFK63_RS16680 3628922 3629497 - septum formation inhibitor Maf Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16680 AFK63_RS16685 AFK63_16705 AFK63_RS16685 3629507 3629995 - rod shape-determining protein MreD part of cell wall structural complex MreBCD%3B transmembrane component gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16685 AFK63_RS16690 AFK63_16710 AFK63_RS16690 3629995 3631008 - rod shape-determining protein MreC gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16690 AFK63_RS16695 AFK63_16715 AFK63_RS16695 3631070 3632113 - rod shape-determining protein MreB gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16695 AFK63_RS16700 AFK63_16720 AFK63_RS16700 3632422 3634362 - regulatory protein CsrD regulates the degradation of the small RNAs CsrB and CsrC%3B may function to targate RNase E to specific RNA molecules gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16700 AFK63_RS16705 AFK63_16725 AFK63_RS16705 3634595 3635569 + quinone oxidoreductase gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16705 AFK63_RS16710 AFK63_16730 AFK63_RS16710 3635674 3636678 + TMAO/DMSO reductase in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase%3B requires inner membrane anchor protein YedZ gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16710 AFK63_RS16715 AFK63_16735 AFK63_RS16715 3636679 3637281 + sulfite oxidase subunit YedZ in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY%3B sulfite oxidase activity not demonstrated%3B contains heme gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16715 AFK63_RS16720 AFK63_16740 AFK63_RS16720 3637523 3637975 + 3-dehydroquinate dehydratase gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16720 AFK63_RS16725 AFK63_16745 AFK63_RS16725 3637998 3638471 + acetyl-CoA carboxylase composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16725 AFK63_RS16730 AFK63_16750 AFK63_RS16730 3638482 3639831 + acetyl-CoA carboxylase an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16730 AFK63_RS16735 AFK63_16755 AFK63_RS16735 3639937 3640179 + membrane protein gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16735 AFK63_RS16740 AFK63_16760 panF panF 3640169 3641623 + sodium/panthothenate symporter mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions%3B member of SSS family of sodium/solute symporters%3B the imported panthothenate is phosphorylated by panthothenate kinase gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16740 AFK63_RS16745 AFK63_16765 prmA prmA 3641632 3642513 + ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16745 AFK63_RS16750 AFK63_16770 AFK63_RS16750 3642696 3643436 + carbonic anhydrase gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16750 AFK63_RS16755 AFK63_16775 AFK63_RS16755 3643810 3644775 + tRNA-dihydrouridine synthase B gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16755 AFK63_RS16760 AFK63_16780 fis fis 3644801 3645097 + Fis family transcriptional regulator Stimulates excision of phage lambda%3B affects Mu development%3B acts as an activator of rRNA and iRNA transcription gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16760 AFK63_RS16765 AFK63_16785 AFK63_RS16765 3645425 3647527 + membrane protein gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16765 AFK63_RS16770 AFK63_16790 AFK63_RS16770 3647572 3648219 - transcriptional regulator gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16770 AFK63_RS16775 AFK63_16795 AFK63_RS16775 3648601 3649743 + MexX family efflux pump subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16775 AFK63_RS16780 AFK63_16800 AFK63_RS16780 3649753 3652872 + multidrug efflux RND transporter permease subunit gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16780 AFK63_RS16785 AFK63_16805 AFK63_RS16785 3653224 3653445 + lipoprotein gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16785 AFK63_RS16790 AFK63_16810 AFK63_RS16790 3653956 3654981 + amino acid ABC transporter substrate-binding protein gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16790 AFK63_RS16795 AFK63_16815 AFK63_RS16795 3655051 3656232 + amino acid ABC transporter permease gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16795 AFK63_RS16800 AFK63_16820 AFK63_RS16800 3656236 3657333 + amino acid ABC transporter permease gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16800 AFK63_RS16805 AFK63_16825 AFK63_RS16805 3657342 3658100 + ABC transporter ATP-binding protein gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16805 AFK63_RS16810 AFK63_16830 AFK63_RS16810 3658283 3658398 - 5S ribosomal RNA rRNA gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16810 AFK63_RS16815 AFK63_16835 AFK63_RS16815 3658436 3658511 - tRNA-Thr tRNA gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16815 AFK63_RS16820 AFK63_16840 AFK63_RS16820 3658526 3658641 - 5S ribosomal RNA rRNA gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16820 AFK63_RS16825 AFK63_16845 AFK63_RS16825 3658718 3661647 - 23S ribosomal RNA rRNA gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16825 AFK63_RS16830 AFK63_16850 AFK63_RS16830 3661841 3661915 - tRNA-Glu tRNA gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16830 AFK63_RS16835 AFK63_16855 AFK63_RS16835 3661993 3663548 - 16S ribosomal RNA rRNA gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16835 AFK63_RS16840 AFK63_16860 purH purH 3664122 3665711 + phosphoribosylaminoimidazolecarboxamide formyltransferase involved in de novo purine biosynthesis gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16840 AFK63_RS16845 AFK63_16865 AFK63_RS16845 3665725 3667023 + phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16845 AFK63_RS16850 AFK63_16870 AFK63_RS16850 3667087 3667743 - membrane protein gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16850 AFK63_RS16855 AFK63_16875 AFK63_RS16855 3667791 3668063 - transcriptional regulator gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16855 AFK63_RS16860 AFK63_16880 AFK63_RS16860 3668250 3668840 - hypothetical protein gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16860 AFK63_RS16865 AFK63_16885 AFK63_RS16865 3668884 3669555 - endonuclease V Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B cleaves DNA containing urea residues%2C AP sites%2C base mismatches%2C insertion/deletion mismatches%2C flaps%2C and pseudo-Y structures gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16865 AFK63_RS16870 AFK63_16890 hemE hemE 3669565 3670629 - uroporphyrinogen decarboxylase catalyzes the formation of coproporphyrinogen from uroporphyrinogen III gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16870 AFK63_RS16875 AFK63_16895 nudC nudC 3670670 3671443 - NADH pyrophosphatase can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH%3B requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16875 AFK63_RS16880 AFK63_16900 AFK63_RS16880 3671546 3672049 + anti-RNA polymerase sigma 70 factor binds specifically to the major sigma factor sigma 70%3B active in stationary phase gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16880 AFK63_RS16885 AFK63_16905 AFK63_RS16885 3672332 3674233 + thiamine biosynthesis protein ThiC catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16885 AFK63_RS16890 AFK63_16910 AFK63_RS16890 3674230 3674865 + thiamine-phosphate pyrophosphorylase catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16890 AFK63_RS16895 AFK63_16915 AFK63_RS16895 3674858 3675607 + molybdopterin biosynthesis protein MoeB ATP-dependent adenylate transferase%2C transfers adenyl moiety to the MoeD subunit of molybdopterin synthase gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16895 AFK63_RS16900 AFK63_16920 AFK63_RS16900 3675597 3675797 + thiamine biosynthesis protein ThiS with ThiF%2C ThiG%2C and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16900 AFK63_RS16905 AFK63_16925 AFK63_RS16905 3675799 3676569 + thiazole synthase gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16905 AFK63_RS16910 AFK63_16930 thiH thiH 3676566 3677699 + thiamine biosynthesis protein ThiH in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS%3B with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine%2C cysteine and 1-deoxy-D-xylulose-5-phosphate%3B forms a complex with ThiG%3B contains an iron-sulfur center gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16910 AFK63_RS16915 AFK63_16935 AFK63_RS16915 3678013 3678321 + PTS cellobiose transporter subunit IIB gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16915 AFK63_RS16920 AFK63_16940 AFK63_RS16920 3678322 3678639 + PTS lactose transporter subunit IIA gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16920 AFK63_RS16925 AFK63_16945 AFK63_RS16925 3679754 3680836 - lipoprotein signal peptide gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16925 AFK63_RS16930 AFK63_16950 AFK63_RS16930 3680978 3685201 - DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16930 AFK63_RS16935 AFK63_16955 rpoB rpoB 3685278 3689306 - DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16935 AFK63_RS16940 AFK63_16960 rplL rplL 3689624 3689992 - 50S ribosomal protein L7/L12 present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16940 AFK63_RS16945 AFK63_16965 rplJ rplJ 3690059 3690556 - 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16945 AFK63_RS16950 AFK63_16970 AFK63_RS16950 3690847 3691551 - 50S ribosomal protein L1 gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16950 AFK63_RS16955 AFK63_16975 AFK63_RS16955 3691555 3691983 - 50S ribosomal protein L11 gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16955 AFK63_RS16960 AFK63_16980 nusG nusG 3692134 3692679 - transcription termination/antitermination protein NusG Modulates Rho-dependent transcription termination gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16960 AFK63_RS16965 AFK63_16985 secE secE 3692681 3693064 - preprotein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16965 AFK63_RS16970 AFK63_16990 tuf tuf 3693299 3694483 - elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16970 AFK63_RS16975 AFK63_16995 AFK63_RS16975 3694596 3694671 - tRNA-Thr tRNA gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16975 AFK63_RS16980 AFK63_17000 AFK63_RS16980 3694678 3694752 - tRNA-Gly tRNA gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16980 AFK63_RS16985 AFK63_17005 AFK63_RS16985 3694862 3694946 - tRNA-Tyr tRNA gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16985 AFK63_RS16990 AFK63_17010 AFK63_RS16990 3694956 3695031 - tRNA-Thr tRNA gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16990 AFK63_RS16995 AFK63_17015 AFK63_RS16995 3695493 3696464 + type I pantothenate kinase gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS16995 AFK63_RS17000 AFK63_17020 AFK63_RS17000 3696500 3697462 - bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17000 AFK63_RS17005 AFK63_17025 murB murB 3697459 3698487 - UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17005 AFK63_RS17010 AFK63_17030 AFK63_RS17010 3698699 3698814 - 5S ribosomal RNA rRNA gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17010 AFK63_RS17015 AFK63_17035 AFK63_RS17015 3698891 3701820 - 23S ribosomal RNA rRNA gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17015 AFK63_RS17020 AFK63_17040 AFK63_RS17020 3701981 3702056 - tRNA-Ala tRNA gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17020 AFK63_RS17025 AFK63_17045 AFK63_RS17025 3702090 3702166 - tRNA-Ile tRNA gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17025 AFK63_RS17030 AFK63_17050 AFK63_RS17030 3702226 3703781 - 16S ribosomal RNA rRNA gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17030 AFK63_RS17035 AFK63_17055 hemG hemG 3704153 3704686 - protoporphyrinogen oxidase catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17035 AFK63_RS17040 AFK63_17060 AFK63_RS17040 3704700 3706151 - potassium transporter gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17040 AFK63_RS17045 AFK63_17065 AFK63_RS17045 3706192 3706803 - hypothetical protein gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17045 AFK63_RS17050 AFK63_17070 AFK63_RS17050 3706803 3708134 - proline dipeptidase catalyzes the hydrolysis of dipeptides with a proline at the C-terminal%3B also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17050 AFK63_RS17055 AFK63_17075 fadB fadB 3708324 3710513 + multifunctional fatty acid oxidation complex subunit alpha includes enoyl-CoA hydratase%2C delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase%2C 3-hydroxyacyl-CoA dehydrogenase%2C and 3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities%3B forms a heterotetramer with FadA%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17055 AFK63_RS17060 AFK63_17080 fadA fadA 3710524 3711687 + 3-ketoacyl-CoA thiolase FadA%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadB%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17060 AFK63_RS17065 AFK63_17085 AFK63_RS17065 3712082 3712429 + hypothetical protein gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17065 AFK63_RS17070 AFK63_17090 fre fre 3712460 3713161 - FMN reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17070 AFK63_RS17075 AFK63_17095 AFK63_RS17075 3713207 3714691 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17075 AFK63_RS17080 AFK63_17100 rfaH rfaH 3714875 3715363 + transcriptional regulator gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17080 AFK63_RS17085 AFK63_17105 AFK63_RS17085 3715398 3715730 - hypothetical protein gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17085 AFK63_RS17090 AFK63_17110 AFK63_RS17090 3715853 3716644 - DNase TatD magnesium dependent%3B involved in quality control of mutated Tat exported substrates%3B not involved in the Sec-independent protein export system gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17090 AFK63_RS17095 AFK63_17115 AFK63_RS17095 3716685 3717446 - preprotein translocase subunit TatC with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17095 AFK63_RS17100 AFK63_17120 AFK63_RS17100 3717448 3718026 - preprotein translocase mediates the export of protein precursors bearing twin-arginine signal peptides gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17100 AFK63_RS17105 AFK63_17125 AFK63_RS17105 3718030 3718293 - preprotein translocase subunit SecA gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17105 AFK63_RS17110 AFK63_17130 ubiB ubiB 3718370 3720010 - ubiquinone biosynthesis protein UbiB an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17110 AFK63_RS17115 AFK63_17135 AFK63_RS17115 3720007 3720612 - membrane protein gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17115 AFK63_RS17120 AFK63_17140 ubiE ubiE 3720624 3721379 - ubiquinone biosynthesis methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17120 AFK63_RS17125 AFK63_17145 AFK63_RS17125 3721469 3722902 - DNA recombination protein RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17125 AFK63_RS17130 AFK63_17150 AFK63_RS17130 3723047 3723802 - uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate%3B involved in the pyrimidine salvage pathway gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17130 AFK63_RS17135 AFK63_17155 AFK63_RS17135 3724062 3724880 + carboxymethylenebutenolidase gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17135 AFK63_RS17140 AFK63_17160 AFK63_RS17140 3724971 3727232 - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17140 AFK63_RS17145 AFK63_17165 AFK63_RS17145 3727533 3727850 - hypothetical protein gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17145 AFK63_RS17150 AFK63_17170 AFK63_RS17150 3727914 3728510 + hypothetical protein gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17150 AFK63_RS17155 AFK63_17175 AFK63_RS17155 3728398 3729297 - membrane protein gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17155 AFK63_RS17160 AFK63_17180 AFK63_RS17160 3729410 3730210 - Cof protein%2C HD superfamily hydrolase gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17160 AFK63_RS17165 AFK63_17185 AFK63_RS17165 3730260 3731252 - lysophospholipase L2 gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17165 AFK63_RS17170 AFK63_17190 rhtB rhtB 3731362 3731982 + homoserine transporter gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17170 AFK63_RS17175 AFK63_17195 AFK63_RS17175 3731983 3732603 - threonine transporter gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17175 AFK63_RS17180 AFK63_17200 AFK63_RS17180 3732662 3734491 - ATP-dependent DNA helicase RecQ functions in blocking illegitimate recombination%2C enhancing topoisomerase activity%2C initiating SOS signaling and clearing blocked replication forks%3B component of the RecF recombinational pathway gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17180 AFK63_RS17185 AFK63_17205 AFK63_RS17185 3734559 3735428 - phospholipase A catalyzes the hydrolysis of phosphatidylcholine gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17185 AFK63_RS17190 AFK63_17210 AFK63_RS17190 3735608 3736078 + hypothetical protein gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17190 AFK63_RS17195 AFK63_17215 AFK63_RS17195 3736131 3737024 + protein rarD gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17195 AFK63_RS17200 AFK63_17220 AFK63_RS17200 3737214 3737600 + hypothetical protein gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17200 AFK63_RS17205 AFK63_17225 AFK63_RS17205 3737659 3738063 + hypothetical protein gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17205 AFK63_RS17210 AFK63_17230 AFK63_RS17210 3738119 3739069 - magnesium transporter CorA responsible for the influx of magnesium ions gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17210 AFK63_RS17215 AFK63_17235 uvrD uvrD 3739550 3741712 - DNA-dependent helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17215 AFK63_RS17220 AFK63_17240 AFK63_RS17220 3741849 3742565 - flavin mononucleotide phosphatase YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17220 AFK63_RS17225 AFK63_17245 xerC xerC 3742565 3743470 - site-specific tyrosine recombinase XerC site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17225 AFK63_RS17230 AFK63_17250 AFK63_RS17230 3743467 3744171 - hypothetical protein gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17230 AFK63_RS17235 AFK63_17255 dapF dapF 3744168 3744992 - diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17235 AFK63_RS17240 AFK63_17260 AFK63_RS17240 3745025 3745228 - membrane protein gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17240 AFK63_RS17245 AFK63_17265 cyaY cyaY 3745395 3745715 + frataxin-like protein iron-dependent inhibitor of iron-sulfur cluster formation%3B iron-binding and oxidizing protein%3B defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease%3B based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17245 AFK63_RS17250 AFK63_17270 cyaA cyaA 3745716 3748262 - adenylate cyclase catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17250 AFK63_RS17255 AFK63_17275 hemC hemC 3748545 3749486 + porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17255 AFK63_RS17260 AFK63_17280 hemD hemD 3749483 3750247 + uroporphyrinogen III methyltransferase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17260 AFK63_RS17265 AFK63_17285 AFK63_RS17265 3750244 3751440 + uroporphyrin-III methyltransferase gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17265 AFK63_RS17270 AFK63_17290 AFK63_RS17270 3751440 3752636 + protoheme IX biogenesis protein gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17270 AFK63_RS17275 AFK63_17295 AFK63_RS17275 3753471 3759002 - hypothetical protein gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17275 AFK63_RS17280 AFK63_17300 AFK63_RS17280 3759655 3759731 - tRNA-Pro tRNA gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17280 AFK63_RS17285 AFK63_17305 AFK63_RS17285 3759768 3759853 - tRNA-Leu tRNA gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17285 AFK63_RS17290 AFK63_17310 AFK63_RS17290 3759876 3759951 - tRNA-His tRNA gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17290 AFK63_RS17295 AFK63_17315 AFK63_RS17295 3760007 3760083 - tRNA-Arg tRNA gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17295 AFK63_RS17300 AFK63_17320 AFK63_RS17300 3760186 3761571 - D-alanine/D-serine/glycine permease involved in the transport across the cytoplasmic membrane of D-alanine%2C D-serine and glycine gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17300 AFK63_RS17305 AFK63_17325 AFK63_RS17305 3761801 3762541 - UDP-N-acetyl-D-mannosaminuronic acid transferase gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17305 AFK63_RS17310 AFK63_17330 AFK63_RS17310 3762555 3763919 - common antigen polymerase enterobacterial common antigen polymerase gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17310 AFK63_RS17315 AFK63_17335 AFK63_RS17315 3763916 3764992 - 4-alpha-L-fucosyltransferase catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17315 AFK63_RS17320 AFK63_17340 AFK63_RS17320 3764989 3766239 - O-antigen translocase involved in the movement of lipid III across the membrane gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17320 AFK63_RS17325 AFK63_17345 AFK63_RS17325 3766241 3767371 - TDP-4-oxo-6-deoxy-D-glucose aminotransferase catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17325 AFK63_RS17330 AFK63_17350 AFK63_RS17330 3767377 3768060 - TDP-fucosamine acetyltransferase gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17330 AFK63_RS17335 AFK63_17355 AFK63_RS17335 3768038 3768919 - glucose-1-phosphate thymidylyltransferase gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17335 AFK63_RS17340 AFK63_17360 AFK63_RS17340 3768938 3770005 - dTDP-glucose 4%2C6-dehydratase gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17340 AFK63_RS17345 AFK63_17365 wecC wecC 3770002 3771264 - UDP-N-acetyl-D-mannosamine dehydrogenase catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17345 AFK63_RS17350 AFK63_17370 AFK63_RS17350 3771261 3772391 - UDP-N-acetylglucosamine 2-epimerase gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17350 AFK63_RS17355 AFK63_17375 AFK63_RS17355 3772449 3773498 - LPS biosynthesis protein Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17355 AFK63_RS17360 AFK63_17380 AFK63_RS17360 3773516 3774616 - UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase catalyzes the formation of alpha-N-acetylglucosaminyl-pyrophosphoryl-undecaprenyl from alpha-N-acetylglucosaminyl 1-phosphate and the lipid carrier undecaprenyl phosphate gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17360 AFK63_RS17365 AFK63_17385 rho rho 3774867 3776126 - transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17365 AFK63_RS17370 AFK63_17390 trxA trxA 3776482 3776811 - thioredoxin gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17370 AFK63_RS17375 AFK63_17395 AFK63_RS17375 3776929 3778194 + ATP-dependent RNA helicase RhlB enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome%2C a multi-enzyme complex important in RNA processing and messenger RNA degradation gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17375 AFK63_RS17380 AFK63_17400 AFK63_RS17380 3778200 3779684 + guanosine polyphosphate pyrophosphohydrolase catalyzes the conversion of guanosine 5'-triphosphate%2C3'-diphosphate (pppGpp) to guanosine 5'-diphosphate%2C3'-diphosphate (ppGpp)%3B pppGpp and ppGpp control the stringent response during amino acid starvation gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17380 AFK63_RS17385 AFK63_17405 AFK63_RS17385 3779745 3781766 - ATP-dependent DNA helicase Rep single-stranded DNA-dependent ATPase%3B initiates unwinding at a nick in the DNA%3B involved in DNA replication gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17385 AFK63_RS17390 AFK63_17410 AFK63_RS17390 3781885 3782166 + peptidyl-prolyl cis-trans isomerase rotamase C%3B accelerates isomerization of the peptidyl prolyl bond gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17390 AFK63_RS17395 AFK63_17415 AFK63_RS17395 3782407 3783882 - ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17395 AFK63_RS17400 AFK63_17420 AFK63_RS17400 3784146 3785039 + transcriptional regulator participates in controlling several genes involved in isoleucine and valine biosynthesis%3B activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17400 AFK63_RS17405 AFK63_17425 AFK63_RS17405 3785036 3786580 - threonine dehydratase threonine deaminase%3B threonine dehydratase%3B in Escherichia coli%2C IlvA is part of the isoleucine biosynthetic pathway gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17405 AFK63_RS17410 AFK63_17430 AFK63_RS17410 3786583 3788433 - dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17410 AFK63_RS17415 AFK63_17435 AFK63_RS17415 3788500 3789429 - branched-chain amino acid aminotransferase gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17415 AFK63_RS17420 AFK63_17440 ilvM ilvM 3789450 3789707 - acetolactate synthase gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17420 AFK63_RS17425 AFK63_17445 AFK63_RS17425 3789704 3791350 - acetolactate synthase catalytic subunit catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17425 AFK63_RS17430 AFK63_17450 AFK63_RS17430 3791941 3793461 + ATP-dependent protease among the AAA+ ATPases%2C the YifB protease family belongs to the Helix 2 insert clade%3B unknown function gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17430 AFK63_RS17435 AFK63_17455 AFK63_RS17435 3793534 3793872 - hypothetical protein gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17435 AFK63_RS17440 AFK63_17460 AFK63_RS17440 3793992 3794813 + HdfR family transcriptional regulator Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17440 AFK63_RS17445 AFK63_17465 AFK63_RS17445 3794919 3794994 - tRNA-Trp tRNA gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17445 AFK63_RS17450 AFK63_17470 AFK63_RS17450 3795003 3795079 - tRNA-Asp tRNA gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17450 AFK63_RS17455 AFK63_17475 AFK63_RS17455 3795134 3795249 - 5S ribosomal RNA rRNA gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17455 AFK63_RS17460 AFK63_17480 AFK63_RS17460 3795326 3798255 - 23S ribosomal RNA rRNA gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17460 AFK63_RS17465 AFK63_17485 AFK63_RS17465 3798416 3798491 - tRNA-Ala tRNA gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17465 AFK63_RS17470 AFK63_17490 AFK63_RS17470 3798525 3798601 - tRNA-Ile tRNA gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17470 AFK63_RS17475 AFK63_17495 AFK63_RS17475 3798661 3800214 - 16S ribosomal RNA rRNA gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17475 AFK63_RS17480 AFK63_17500 AFK63_RS17480 3800579 3801430 - glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17480 AFK63_RS17485 AFK63_17505 btuB btuB 3801375 3803228 - vitamin B12/cobalamin outer membrane transporter involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17485 AFK63_RS17490 AFK63_17510 AFK63_RS17490 3803602 3804702 + tRNA (uracil-5-)-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17490 AFK63_RS17495 AFK63_17515 AFK63_RS17495 3804733 3805092 - hypothetical protein gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17495 AFK63_RS17500 AFK63_17520 AFK63_RS17500 3805103 3805738 - transcriptional regulator negatively controls the expression of fabA and fabB%2C genes involved in the unsaturated fatty acid biosynthesis gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17500 AFK63_RS17505 AFK63_17525 AFK63_RS17505 3805935 3807335 + pyridine nucleotide transhydrogenase catalyzes the conversion of NADPH to NADH gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17505 AFK63_RS17510 AFK63_17530 AFK63_RS17510 3807318 3808235 - transcriptional regulator Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG%2C gor%2C ahpC%2C ahpF%2C oxyS%2C dps%2C fur and grxA gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17510 AFK63_RS17515 AFK63_17535 AFK63_RS17515 3808515 3809888 - argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17515 AFK63_RS17520 AFK63_17540 AFK63_RS17520 3810100 3811317 - Argininosuccinate synthase gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17520 AFK63_RS17525 AFK63_17545 AFK63_RS17525 3811379 3812152 - acetylglutamate kinase gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17525 AFK63_RS17530 AFK63_17550 AFK63_RS17530 3812170 3813174 - N-acetyl-gamma-glutamyl-phosphate reductase gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17530 AFK63_RS17535 AFK63_17555 AFK63_RS17535 3813355 3814506 + acetylornithine deacetylase catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17535 AFK63_RS17540 AFK63_17560 AFK63_RS17540 3815108 3817759 + phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17540 AFK63_RS17545 AFK63_17565 AFK63_RS17545 3818060 3819715 - malate:quinone oxidoreductase gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17545 AFK63_RS17550 AFK63_17570 AFK63_RS17550 3819991 3821280 - methyl-accepting chemotaxis protein gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17550 AFK63_RS17555 AFK63_17575 AFK63_RS17555 3822009 3822617 - hypothetical protein gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17555 AFK63_RS17560 AFK63_17580 AFK63_RS17560 3822620 3835504 - Contact-dependent inhibition of growth factor CdiA gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17560 AFK63_RS17565 AFK63_17585 AFK63_RS17565 3835517 3837181 - peptide transporter gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17565 AFK63_RS17570 AFK63_17590 metF metF 3837561 3838457 - 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17570 AFK63_RS17575 AFK63_17595 metL metL 3838778 3841210 - aspartate kinase multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17575 AFK63_RS17580 AFK63_17600 AFK63_RS17580 3841220 3842374 - cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17580 AFK63_RS17585 AFK63_17605 AFK63_RS17585 3842656 3842973 + met repressor when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17585 AFK63_RS17590 AFK63_17610 rpmE rpmE 3843066 3843278 - 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17590 AFK63_RS17595 AFK63_17615 AFK63_RS17595 3843482 3845677 + primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17595 AFK63_RS17600 AFK63_17620 AFK63_RS17600 3845836 3846870 + transcriptional regulator gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17600 AFK63_RS17605 AFK63_17625 AFK63_RS17605 3846957 3847991 + cell division protein FtsN gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17605 AFK63_RS17610 AFK63_17630 AFK63_RS17610 3848083 3848613 + ATP-dependent protease subunit HslV heat shock protein involved in degradation of misfolded proteins gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17610 AFK63_RS17615 AFK63_17635 hslU hslU 3848623 3849954 + ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17615 AFK63_RS17620 AFK63_17640 AFK63_RS17620 3850135 3851067 + 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17620 AFK63_RS17625 AFK63_17645 AFK63_RS17625 3851160 3851645 + ribonuclease E activity regulator RraA regulator of RNase E%3B increases half-life and abundance of RNAs%3B interacts with RNase E possibly inhibiting catalytic activity gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17625 AFK63_RS17630 AFK63_17650 AFK63_RS17630 3851696 3851935 - hypothetical protein interacts with FisZ and is necessary for Z-ring formation gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17630 AFK63_RS17635 AFK63_17655 AFK63_RS17635 3852370 3853218 + glycerol uptake facilitator GlpF involved in the transport of glycerol into the cell gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17635 AFK63_RS17640 AFK63_17660 glpK glpK 3853241 3854755 + glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17640 AFK63_RS17645 AFK63_17665 AFK63_RS17645 3854885 3855247 + hypothetical protein gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17645 AFK63_RS17650 AFK63_17670 AFK63_RS17650 3855616 3857271 + L-lactate permease gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17650 AFK63_RS17655 AFK63_17675 AFK63_RS17655 3857268 3858056 + transcriptional regulator represses the lctPRD operon gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17655 AFK63_RS17660 AFK63_17680 lldD lldD 3858053 3859258 + lactate dehydrogenase flavin mononucleotide-dependent dehydrogenase%3B functions in aerobic respiration and also has a role in anaerobic nitrate respiration gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17660 AFK63_RS17665 AFK63_17685 AFK63_RS17665 3859373 3860050 - 6-N-hydroxylaminopurine resistance protein gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17665 AFK63_RS17670 AFK63_17690 AFK63_RS17670 3860121 3860741 - superoxide dismutase SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17670 AFK63_RS17675 AFK63_17695 AFK63_RS17675 3861114 3862151 + rhamnose:proton symporter transports L-rhamnose and L-lyxose into the cell gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17675 AFK63_RS17680 AFK63_17700 AFK63_RS17680 3862148 3862999 - transcriptional regulator activates the expression of rhaRS in response to L-rhamnose gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17680 AFK63_RS17685 AFK63_17705 AFK63_RS17685 3863071 3863907 - AraC family transcriptional regulator gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17685 AFK63_RS17690 AFK63_17710 AFK63_RS17690 3864209 3865681 + rhamnulokinase gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17690 AFK63_RS17695 AFK63_17715 AFK63_RS17695 3865678 3866934 + L-rhamnose isomerase catalyzes the formation of L-rhamnulose from L-rhamnose gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17695 AFK63_RS17700 AFK63_17720 AFK63_RS17700 3866944 3867768 + rhamnulose-1-phosphate aldolase gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17700 AFK63_RS17705 AFK63_17725 AFK63_RS17705 3867868 3868860 + ABC transporter substrate-binding protein gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17705 AFK63_RS17710 AFK63_17730 AFK63_RS17710 3869039 3870550 + hypothetical protein gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17710 AFK63_RS17715 AFK63_17735 AFK63_RS17715 3870547 3871551 + branched-chain amino acid ABC transporter permease gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17715 AFK63_RS17720 AFK63_17740 AFK63_RS17720 3871548 3872558 + branched-chain amino acid ABC transporter permease gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17720 AFK63_RS17725 AFK63_17745 AFK63_RS17725 3872630 3873778 + alcohol dehydrogenase gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17725 AFK63_RS17730 AFK63_17750 AFK63_RS17730 3873775 3874089 + L-rhamnose mutarotase gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17730 AFK63_RS17735 AFK63_17755 lacY lacY 3874215 3875477 - galactoside permease lactose/proton symporter%3B mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides%3B member of major facilitator superfamily%3B functions as a monomer with 12 transmembrane segments gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17735 AFK63_RS17740 AFK63_17760 AFK63_RS17740 3875534 3877657 - alpha-galactosidase gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17740 AFK63_RS17745 AFK63_17765 AFK63_RS17745 3877775 3878782 - transcriptional regulator gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17745 AFK63_RS17750 AFK63_17770 AFK63_RS17750 3878857 3879405 - DNA-binding protein gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17750 AFK63_RS17755 AFK63_17775 AFK63_RS17755 3879507 3880169 + branched-chain amino acid ABC transporter permease gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17755 AFK63_RS17760 AFK63_17780 AFK63_RS17760 3880169 3880492 + branched-chain amino acid transport gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17760 AFK63_RS17765 AFK63_17785 AFK63_RS17765 3880531 3880740 - DUF1471 domain-containing protein gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17765 AFK63_RS17770 AFK63_17790 AFK63_RS17770 3880868 3881713 - formate dehydrogenase gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17770 AFK63_RS17775 AFK63_17795 AFK63_RS17775 3881879 3882466 + sulfate ABC transporter substrate-binding protein gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17775 AFK63_RS17780 AFK63_17800 AFK63_RS17780 3882515 3884929 + formate dehydrogenase gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17780 AFK63_RS17785 AFK63_17805 AFK63_RS17785 3884942 3885844 + formate dehydrogenase O subunit beta beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17785 AFK63_RS17790 AFK63_17810 AFK63_RS17790 3885841 3886476 + formate dehydrogenase cytochrome b556(FDO) component%3B heme containing gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17790 AFK63_RS17795 AFK63_17815 AFK63_RS17795 3886473 3887402 + formate dehydrogenase accessory protein FdhE required for the formation of active formate dehydrogenase gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17795 AFK63_RS17800 AFK63_17820 AFK63_RS17800 3887780 3888604 - transcriptional regulator gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17800 AFK63_RS17805 AFK63_17825 AFK63_RS17805 3888866 3890269 + permease gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17805 AFK63_RS17810 AFK63_17830 AFK63_RS17810 3890281 3892248 + hypothetical protein gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17810 AFK63_RS17815 AFK63_17835 AFK63_RS17815 3892271 3892873 - hypothetical protein gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17815 AFK63_RS17820 AFK63_17840 AFK63_RS17820 3893030 3893902 + sugar kinase gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17820 AFK63_RS17825 AFK63_17845 AFK63_RS17825 3893927 3895078 - alcohol dehydrogenase gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17825 AFK63_RS17830 AFK63_17850 AFK63_RS17830 3895298 3897145 - selenocysteine-specific translation elongation factor gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17830 AFK63_RS17835 AFK63_17855 AFK63_RS17835 3897142 3898524 - L-seryl-tRNA(Sec) selenium transferase catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17835 AFK63_RS17840 AFK63_17860 AFK63_RS17840 3898644 3899252 - glutathione S-transferase gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17840 AFK63_RS17845 AFK63_17865 AFK63_RS17845 3899786 3901702 + PTS mannitol transporter subunit IICBA catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIC forms the translocation channel and contains the specific substrate-binding site%3B subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit%3B subunit IIB transfers the phosphoryl group to the substrate gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17845 AFK63_RS17850 AFK63_17870 AFK63_RS17850 3901889 3903037 + mannitol-1-phosphate 5-dehydrogenase gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17850 AFK63_RS17855 AFK63_17875 mtlR mtlR 3903086 3903625 + mannitol repressor protein Acts as a repressor of the mtlAD operon gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17855 AFK63_RS17860 AFK63_17880 AFK63_RS17860 3903736 3904746 + fructose 1%2C6-bisphosphatase gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17860 AFK63_RS17865 AFK63_17885 AFK63_RS17865 3904840 3905586 + ferredoxin-NADP reductase gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17865 AFK63_RS17870 AFK63_17890 AFK63_RS17870 3905587 3906006 - membrane protein gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17870 AFK63_RS17875 AFK63_17895 AFK63_RS17875 3906121 3906720 + hypothetical protein gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17875 AFK63_RS17880 AFK63_17900 AFK63_RS17880 3906827 3907594 + triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17880 AFK63_RS17885 AFK63_17905 AFK63_RS17885 3907655 3908062 - hypothetical protein gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17885 AFK63_RS17890 AFK63_17910 AFK63_RS17890 3908653 3909093 - cell wall assembly protein gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17890 AFK63_RS17895 AFK63_17915 AFK63_RS17895 3909278 3909694 - hypothetical protein gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17895 AFK63_RS17900 AFK63_17920 AFK63_RS17900 3909835 3910194 - hypothetical protein gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17900 AFK63_RS17905 AFK63_17925 AFK63_RS17905 3910284 3911234 - hypothetical protein gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17905 AFK63_RS17910 AFK63_17930 AFK63_RS17910 3911474 3911926 - hypothetical protein gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17910 AFK63_RS17915 AFK63_RS17915 AFK63_RS17915 3912147 3913272 - hypothetical protein gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17915 AFK63_RS17920 AFK63_17940 AFK63_RS17920 3914046 3914399 - hypothetical protein gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17920 AFK63_RS17925 AFK63_17945 AFK63_RS17925 3914528 3914812 - hypothetical protein gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17925 AFK63_RS17930 AFK63_17950 AFK63_RS17930 3915350 3915886 - nuclease gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17930 AFK63_RS17935 AFK63_17955 AFK63_RS17935 3916300 3917382 - hypothetical protein gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17935 AFK63_RS17940 AFK63_17960 AFK63_RS17940 3917816 3918358 - hypothetical protein gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17940 AFK63_RS17945 AFK63_17965 AFK63_RS17945 3918811 3922989 - type IV secretion protein Rhs gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17945 AFK63_RS17950 AFK63_17970 AFK63_RS17950 3922992 3923423 - hypothetical protein gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17950 AFK63_RS17955 AFK63_17975 AFK63_RS17955 3923420 3925348 - type IV secretion protein Rhs gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17955 AFK63_RS17960 AFK63_17980 AFK63_RS17960 3926082 3926591 - hypothetical protein gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17960 AFK63_RS17965 AFK63_17985 AFK63_RS17965 3926818 3927342 - hypothetical protein gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17965 AFK63_RS17970 AFK63_17990 AFK63_RS17970 3927421 3927615 - hypothetical protein gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17970 AFK63_RS17975 AFK63_17995 AFK63_RS17975 3928589 3928903 - hypothetical protein gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17975 AFK63_RS17980 AFK63_18000 AFK63_RS17980 3929532 3929924 - hypothetical protein gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17980 AFK63_RS17985 AFK63_18005 AFK63_RS17985 3930091 3930489 - hypothetical protein gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17985 AFK63_RS17990 AFK63_18010 AFK63_RS17990 3930486 3934451 - type IV secretion protein Rhs gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17990 AFK63_RS17995 AFK63_18015 AFK63_RS17995 3934673 3935353 - accessory protein gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS17995 AFK63_RS18000 AFK63_18020 AFK63_RS18000 3935451 3936746 - phospholipase gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18000 AFK63_RS18005 AFK63_18025 AFK63_RS18005 3936739 3937890 - hypothetical protein gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18005 AFK63_RS18010 AFK63_18030 AFK63_RS18010 3937892 3940030 - type IV secretion protein Rhs gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18010 AFK63_RS18015 AFK63_18035 AFK63_RS18015 3940187 3940633 - hypothetical protein gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18015 AFK63_RS18020 AFK63_18040 AFK63_RS18020 3940811 3941203 - type VI secretion protein gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18020 AFK63_RS18025 AFK63_18045 AFK63_RS18025 3941209 3941814 - hypothetical protein gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18025 AFK63_RS18030 AFK63_18050 AFK63_RS18030 3941824 3942894 - Uncharacterized low-complexity proteins gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18030 AFK63_RS18035 AFK63_18055 AFK63_RS18035 3942891 3945431 - hypothetical protein gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18035 AFK63_RS18040 AFK63_18060 AFK63_RS18040 3945961 3946293 - hypothetical protein gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18040 AFK63_RS18045 AFK63_18065 AFK63_RS18045 3946904 3948499 - hypothetical protein gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18045 AFK63_RS18050 AFK63_18070 AFK63_RS18050 3948645 3949403 - accessory protein gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18050 AFK63_RS18055 AFK63_18075 AFK63_RS18055 3949400 3950866 - phospholipase A1 gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18055 AFK63_RS18060 AFK63_18080 AFK63_RS18060 3950992 3952422 - nuclease PIN gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18060 AFK63_RS18065 AFK63_18085 AFK63_RS18065 3952453 3955068 - molecular chaperone gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18065 AFK63_RS18070 AFK63_18090 AFK63_RS18070 3955287 3956330 - hypothetical protein gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18070 AFK63_RS18075 AFK63_18095 AFK63_RS18075 3956327 3958198 - type VI secretion system protein ImpG gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18075 AFK63_RS18080 AFK63_18100 AFK63_RS18080 3958201 3958770 - hypothetical protein gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18080 AFK63_RS18085 AFK63_18105 AFK63_RS18085 3958763 3959602 - protein of avirulence locus ImpE gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18085 AFK63_RS18090 AFK63_18110 AFK63_RS18090 3959628 3960623 - hypothetical protein gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18090 AFK63_RS18095 AFK63_18115 AFK63_RS18095 3960642 3961436 - serine/threonine phosphatase gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18095 AFK63_RS18100 AFK63_18120 AFK63_RS18100 3961433 3963367 - hypothetical protein gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18100 AFK63_RS18105 AFK63_18125 AFK63_RS18105 3963595 3963987 - hypothetical protein gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18105 AFK63_RS18110 AFK63_18130 AFK63_RS18110 3964013 3964378 - type VI secretion protein gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18110 AFK63_RS18115 AFK63_18135 AFK63_RS18115 3964427 3964909 - type VI secretion protein ImpD gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18115 AFK63_RS18120 AFK63_18140 AFK63_RS18120 3965115 3965513 - hypothetical protein gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18120 AFK63_RS18125 AFK63_18145 AFK63_RS18125 3965555 3965998 - hypothetical protein gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18125 AFK63_RS18130 AFK63_18150 AFK63_RS18130 3966005 3966424 - hypothetical protein gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18130 AFK63_RS18135 AFK63_18155 AFK63_RS18135 3966492 3967991 - type VI secretion protein EvpB gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18135 AFK63_RS18140 AFK63_18160 AFK63_RS18140 3967995 3968519 - type VI secretion protein ImpB gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18140 AFK63_RS18145 AFK63_18165 AFK63_RS18145 3968595 3969617 - hypothetical protein gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18145 AFK63_RS18150 AFK63_18170 AFK63_RS18150 3969627 3970337 - protein phosphatase ImpM gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18150 AFK63_RS18155 AFK63_18175 AFK63_RS18155 3970354 3973971 - type VI secretion system protein ImpL gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18155 AFK63_RS18160 AFK63_18180 AFK63_RS18160 3973974 3975209 - hypothetical protein gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18160 AFK63_RS18165 AFK63_18185 AFK63_RS18165 3975227 3976570 - type VI secretion protein gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18165 AFK63_RS18170 AFK63_18190 AFK63_RS18170 3976595 3977101 - type VI secretion lipoprotein/VasD gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18170 AFK63_RS18175 AFK63_18195 AFK63_RS18175 3977126 3977620 - hypothetical protein gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18175 AFK63_RS18180 AFK63_18200 AFK63_RS18180 3978859 3978948 + toxic peptide TisB gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18180 AFK63_RS18185 AFK63_18205 AFK63_RS18185 3979024 3979479 + GCN5 family acetyltransferase gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18185 AFK63_RS18190 AFK63_18210 AFK63_RS18190 3979688 3980875 + multidrug resistance protein D gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18190 AFK63_RS18195 AFK63_18215 AFK63_RS18195 3980778 3981869 - periplasmic protein gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18195 AFK63_RS18200 AFK63_18220 AFK63_RS18200 3981941 3982282 - membrane protein gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18200 AFK63_RS18205 AFK63_18225 AFK63_RS18205 3982272 3982619 - membrane protein gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18205 AFK63_RS18210 AFK63_18230 AFK63_RS18210 3982658 3983446 - hypothetical protein gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18210 AFK63_RS18215 AFK63_18235 AFK63_RS18215 3983552 3984043 - molecular chaperone gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18215 AFK63_RS18220 AFK63_18240 AFK63_RS18220 3984154 3984570 - heat-shock protein A with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18220 AFK63_RS18225 AFK63_18245 AFK63_RS18225 3984876 3985202 + membrane protein gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18225 AFK63_RS18230 AFK63_18250 AFK63_RS18230 3985203 3986465 - hypothetical protein gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18230 AFK63_RS18235 AFK63_18255 AFK63_RS18235 3986534 3987466 - hydroxyacid dehydrogenase gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18235 AFK63_RS18240 AFK63_18260 AFK63_RS18240 3987476 3988786 - MFS transporter gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18240 AFK63_RS18245 AFK63_18265 AFK63_RS18245 3988924 3990216 - glucarate transporter gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18245 AFK63_RS18250 AFK63_18270 AFK63_RS18250 3990541 3991689 - galactonate dehydratase gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18250 AFK63_RS18255 AFK63_18275 AFK63_RS18255 3991686 3992303 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate%3B functions in galactonate metabolism gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18255 AFK63_RS18260 AFK63_18280 AFK63_RS18260 3992287 3993171 - 2-oxo-3-deoxygalactonate kinase catalyzes the formation of 2-dehydro-3-deoxy-D-galactonate 6-phosphate from 2-dehydro-3-deoxy-D-galactonate gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18260 AFK63_RS18265 AFK63_18285 AFK63_RS18265 3993168 3993851 - transcriptional regulator gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18265 AFK63_RS18270 AFK63_18290 AFK63_RS18270 3994628 3995440 - sugar phosphatase YidA%3B catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate)%2C mannose 1-phosphate and p-nitrophenyl phosphate%3B hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form%3B member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18270 AFK63_RS18275 AFK63_18295 gyrB gyrB 3995745 3998159 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18275 AFK63_RS18280 AFK63_18300 recF recF 3998188 3999261 - recombination protein F Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18280 AFK63_RS18285 AFK63_18305 AFK63_RS18285 3999401 4000501 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18285 AFK63_RS18290 AFK63_18310 dnaA dnaA 4000506 4001891 - chromosomal replication initiator protein DnaA binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18290 AFK63_RS18295 AFK63_18315 rnpA rnpA 4002655 4003014 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18295 AFK63_RS18300 AFK63_18320 AFK63_RS18300 4003238 4004887 + membrane protein insertase functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18300 AFK63_RS18305 AFK63_18325 trmE trmE 4004993 4006357 + tRNA modification GTPase TrmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18305 AFK63_RS18310 AFK63_18330 AFK63_RS18310 4006444 4007721 - MFS transporter gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18310 AFK63_RS18315 AFK63_18335 AFK63_RS18315 4007723 4008676 - hypothetical protein gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18315 AFK63_RS18320 AFK63_18340 AFK63_RS18320 4008678 4008941 - hypothetical protein gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18320 AFK63_RS18325 AFK63_18345 AFK63_RS18325 4008951 4010165 - monooxygenase gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18325 AFK63_RS18330 AFK63_18350 AFK63_RS18330 4010176 4011468 - diaminobutyrate--2-oxoglutarate transaminase catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18330 AFK63_RS18335 AFK63_18355 AFK63_RS18335 4011502 4012842 - ornithine monooxygenase gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18335 AFK63_RS18340 AFK63_18360 AFK63_RS18340 4012855 4013232 - hypothetical protein gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18340 AFK63_RS18345 AFK63_18365 AFK63_RS18345 4013327 4013725 - Rhodanese-related sulfurtransferase gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18345 AFK63_RS18350 AFK63_18370 AFK63_RS18350 4013733 4014608 - esterase gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18350 AFK63_RS18355 AFK63_18375 AFK63_RS18355 4014605 4015519 - hypothetical protein gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18355 AFK63_RS18360 AFK63_18380 AFK63_RS18360 4015516 4016565 - FAD-dependent oxidoreductase gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18360 AFK63_RS18365 AFK63_RS18365 AFK63_RS18365 4016565 4017212 - cupin gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18365 AFK63_RS18370 AFK63_18390 AFK63_RS18370 4017190 4018827 - amino acid adenylation protein gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18370 AFK63_RS18375 AFK63_18395 AFK63_RS18375 4018832 4020085 - membrane protein gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18375 AFK63_RS18380 AFK63_18400 AFK63_RS18380 4020073 4020543 - acetyltransferase gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18380 AFK63_RS18385 AFK63_18405 AFK63_RS18385 4020534 4020998 - hypothetical protein gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18385 AFK63_RS18390 AFK63_18410 AFK63_RS18390 4020995 4022431 - methionyl-tRNA synthetase gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18390 AFK63_RS18395 AFK63_18415 AFK63_RS18395 4022526 4022852 - hypothetical protein gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18395 AFK63_RS18400 AFK63_18420 AFK63_RS18400 4022828 4023550 - branched-chain amino acid permease (azaleucine resistance) gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18400 AFK63_RS18405 AFK63_18425 AFK63_RS18405 4023532 4024014 - ribosomal-protein-S18p-alanine acetyltransferase gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18405 AFK63_RS18410 AFK63_18430 AFK63_RS18410 4023998 4024744 - protein BsmA gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18410 AFK63_RS18415 AFK63_18435 AFK63_RS18415 4024986 4025846 + LysR family transcriptional regulator gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18415 AFK63_RS18420 AFK63_18440 AFK63_RS18420 4026075 4026824 + hypothetical protein gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18420 AFK63_RS18425 AFK63_18445 AFK63_RS18425 4026854 4027420 + hypothetical protein gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18425 AFK63_RS18430 AFK63_18450 AFK63_RS18430 4027456 4028793 - adenine permease PurP involved in the transport or adenine gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18430 AFK63_RS18435 AFK63_18455 AFK63_RS18435 4028963 4029628 + 6-phosphogluconate phosphatase YieH%3B catalyzes the dephosphorylation of phosphoenolpyruvate%2C AMP and p-nitrophenyl phosphate%3B purine and pyrimidine nucleotides are secondary substrates%3B member of the haloacid dehalogenase-like hydrolases superfamily gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18435 AFK63_RS18440 AFK63_18460 AFK63_RS18440 4029766 4030938 - glycoside hydrolase gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18440 AFK63_RS18445 AFK63_18465 AFK63_RS18445 4031052 4031777 - PhoU family transcriptional regulator regulates several genes involved in high affinity phosphate uptake%3B under conditions of high phosphate concentrations downregulates the PHO regulon gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18445 AFK63_RS18450 AFK63_18470 AFK63_RS18450 4031836 4032609 - phosphate ABC transporter ATP-binding protein gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18450 AFK63_RS18455 AFK63_18475 pstA pstA 4032660 4033550 - phosphate transporter permease subunit PtsA Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18455 AFK63_RS18460 AFK63_18480 pstC pstC 4033550 4034509 - phosphate transporter permease subunit PstC part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18460 AFK63_RS18465 AFK63_18485 AFK63_RS18465 4034649 4035689 - phosphate ABC transporter substrate-binding protein gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18465 AFK63_RS18470 AFK63_18490 AFK63_RS18470 4035942 4036559 - hypothetical protein gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18470 AFK63_RS18475 AFK63_18495 AFK63_RS18475 4036643 4038472 - glucosamine--fructose-6-phosphate aminotransferase Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18475 AFK63_RS18480 AFK63_18500 glmU glmU 4038696 4040066 - bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18480 AFK63_RS18485 AFK63_18505 atpC atpC 4040712 4041131 - ATP synthase F0F1 subunit epsilon part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18485 AFK63_RS18490 AFK63_18510 AFK63_RS18490 4041152 4042534 - ATP synthase subunit beta gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18490 AFK63_RS18495 AFK63_18515 AFK63_RS18495 4042561 4043424 - ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18495 AFK63_RS18500 AFK63_18520 AFK63_RS18500 4043475 4045016 - ATP F0F1 synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18500 AFK63_RS18505 AFK63_18525 AFK63_RS18505 4045029 4045562 - ATP F0F1 synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18505 AFK63_RS18510 AFK63_18530 AFK63_RS18510 4045577 4046047 - ATP synthase subunit b Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18510 AFK63_RS18515 AFK63_18535 AFK63_RS18515 4046112 4046351 - ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18515 AFK63_RS18520 AFK63_18540 AFK63_RS18520 4046402 4047220 - ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18520 AFK63_RS18525 AFK63_18545 AFK63_RS18525 4047229 4047609 - ATP F0F1 synthase subunit I Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18525 AFK63_RS18530 AFK63_18550 gidB gidB 4048221 4048844 - 16S rRNA methyltransferase glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18530 AFK63_RS18535 AFK63_18555 AFK63_RS18535 4048902 4050791 - hypothetical protein gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18535 AFK63_RS18540 AFK63_18560 AFK63_RS18540 4051172 4051612 - FMN-binding protein MioC An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18540 AFK63_RS18545 AFK63_18565 AFK63_RS18545 4051702 4052160 - transcriptional regulator transcriptional repressor of asnA which codes for aspartate-ammonia ligase gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18545 AFK63_RS18550 AFK63_18570 AFK63_RS18550 4052314 4053306 + asparagine synthetase AsnA catalyzes the formation of asparagine from aspartate and ammonia gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18550 AFK63_RS18555 AFK63_18575 AFK63_RS18555 4053309 4054760 - hypothetical protein contains a von Willibrand factor type A domain%3B stimulates the ATPase activity of RavA gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18555 AFK63_RS18560 AFK63_18580 AFK63_RS18560 4054754 4056253 - ATPase interacts with LdcI%2C lysine decarboxylase%3B may be active in late log/ early stationary phase gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18560 AFK63_RS18565 AFK63_18585 trkD trkD 4056474 4058345 + potassium transporter Kup Responsible for the low-affinity transport of potassium into the cell%3B involved in potassium ion uptake under hyper-osmotic stress at a low pH gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18565 AFK63_RS18570 AFK63_18590 AFK63_RS18570 4058528 4058947 + D-ribose pyranase cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose%3B RbsD is required for efficient ribose utilization in E. coli%3B rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18570 AFK63_RS18575 AFK63_18595 AFK63_RS18575 4058955 4060460 + sugar ABC transporter ATP-binding protein gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18575 AFK63_RS18580 AFK63_18600 rbsC rbsC 4060468 4061433 + ribose ABC transporter permease functions to transport ribose at high affinity%3B forms a complex with RbsA2C2B gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18580 AFK63_RS18585 AFK63_18605 AFK63_RS18585 4061460 4062347 + D-ribose transporter subunit RbsB periplasmic substrate-binding component of the ATP-dependent ribose transport system gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18585 AFK63_RS18590 AFK63_18610 AFK63_RS18590 4062416 4063345 + ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18590 AFK63_RS18595 AFK63_18615 AFK63_RS18595 4063351 4064343 + transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18595 AFK63_RS18600 AFK63_18620 AFK63_RS18600 4064340 4065734 - MFS transporter gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18600 AFK63_RS18605 AFK63_18625 AFK63_RS18605 4065748 4066449 - GntR family transcriptional regulator gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18605 AFK63_RS18610 AFK63_18630 AFK63_RS18610 4066913 4068466 + 16S ribosomal RNA rRNA gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18610 AFK63_RS18615 AFK63_18635 AFK63_RS18615 4068536 4068611 + tRNA-Glu tRNA gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18615 AFK63_RS18620 AFK63_18640 AFK63_RS18620 4068805 4071734 + 23S ribosomal RNA rRNA gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18620 AFK63_RS18625 AFK63_18645 AFK63_RS18625 4071811 4071926 + 5S ribosomal RNA rRNA gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18625 AFK63_RS18630 AFK63_18650 AFK63_RS18630 4072057 4072569 - molybdopterin-guanine dinucleotide biosynthesis protein B in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18630 AFK63_RS18635 AFK63_18655 mobA mobA 4072569 4073147 - molybdopterin-guanine dinucleotide biosynthesis protein MobA in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18635 AFK63_RS18640 AFK63_18660 AFK63_RS18640 4073214 4073483 + hypothetical protein gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18640 AFK63_RS18645 AFK63_18665 AFK63_RS18645 4073560 4074546 + serine/threonine protein kinase catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro%3B specific substrate in vivo has not been identified yet%3B plays a role in long-term cell survival and expression of surface appendages gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18645 AFK63_RS18650 AFK63_18670 AFK63_RS18650 4074574 4075197 + protein disulfide isomerase gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18650 AFK63_RS18655 AFK63_18675 AFK63_RS18655 4075226 4076134 - acyltransferase gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18655 AFK63_RS18660 AFK63_18680 AFK63_RS18660 4076563 4079346 + DNA polymerase I gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18660 AFK63_RS18665 AFK63_18685 AFK63_RS18665 4079662 4080297 - GTP-binding protein gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18665 AFK63_RS18670 AFK63_18690 AFK63_RS18670 4080888 4081406 + GTPase activator gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18670 AFK63_RS18675 AFK63_18695 AFK63_RS18675 4081591 4082964 + coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18675 AFK63_RS18680 AFK63_18700 glnG glnG 4083223 4084632 - nitrogen regulation protein NR(I) response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes%3B interacts with sigma-54 gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18680 AFK63_RS18685 AFK63_18705 glnL glnL 4084641 4085690 - PAS domain-containing two-component system sensor histidine kinase sensory histidine kinase in two-component regulatory system with GlnG%3B acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18685 AFK63_RS18690 AFK63_18710 glnA glnA 4085890 4087299 - glutamine synthetase forms a homododecamer%3B forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate%3B also functions in the assimilation of ammonia%3B highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues%3B addition of adenylyl groups results in inactivation of the enzyme gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18690 AFK63_RS18695 AFK63_18715 AFK63_RS18695 4087678 4089501 + GTP-binding protein gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18695 AFK63_RS18700 AFK63_18720 AFK63_RS18700 4089579 4091015 - sugar transporter gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18700 AFK63_RS18705 AFK63_18725 AFK63_RS18705 4091068 4092474 - membrane protein gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18705 AFK63_RS18710 AFK63_18730 AFK63_RS18710 4092519 4094543 - alpha-xylosidase gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18710 AFK63_RS18715 AFK63_18735 AFK63_RS18715 4094600 4095844 - sugar isomerase gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18715 AFK63_RS18720 AFK63_18740 AFK63_RS18720 4095859 4096734 - aldolase gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18720 AFK63_RS18725 AFK63_18745 AFK63_RS18725 4096758 4097657 - gamma-hydroxybutyrate dehydrogenase catalyzes the formation of gamma hydroxybutyrate from succinate semialdehyde gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18725 AFK63_RS18730 AFK63_18750 AFK63_RS18730 4097870 4098769 + sugar kinase gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18730 AFK63_RS18735 AFK63_18755 AFK63_RS18735 4098806 4099612 + DeoR family transcriptional regulator gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18735 AFK63_RS18740 AFK63_18760 AFK63_RS18740 4099721 4100320 + alpha-D-glucose-1-phosphatase gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18740 AFK63_RS18745 AFK63_18765 AFK63_RS18745 4100314 4101183 + hypothetical protein gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18745 AFK63_RS18750 AFK63_18770 AFK63_RS18750 4101180 4101617 + D-tyrosyl-tRNA(Tyr) deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18750 AFK63_RS18755 AFK63_18775 AFK63_RS18755 4101662 4102603 + hypothetical protein gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18755 AFK63_RS18760 AFK63_18780 AFK63_RS18760 4102694 4104376 - hypothetical protein gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18760 AFK63_RS18765 AFK63_18785 AFK63_RS18765 4104498 4105898 - xanthine permease XanP high-affinity transporter for xanthine gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18765 AFK63_RS18770 AFK63_18790 AFK63_RS18770 4106216 4106665 - hypothetical protein gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18770 AFK63_RS18775 AFK63_18795 AFK63_RS18775 4107066 4107593 - fimbrial protein gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18775 AFK63_RS18780 AFK63_RS18780 AFK63_RS18780 4107657 4108232 - hypothetical protein gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18780 AFK63_RS18785 AFK63_18805 AFK63_RS18785 4108285 4108824 - hypothetical protein gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18785 AFK63_RS18790 AFK63_18810 AFK63_RS18790 4108884 4109405 - hypothetical protein gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18790 AFK63_RS18795 AFK63_18815 AFK63_RS18795 4109466 4110008 - hypothetical protein gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18795 AFK63_RS18800 AFK63_18820 AFK63_RS18800 4110116 4111093 - fimbrial protein gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18800 AFK63_RS18805 AFK63_18825 AFK63_RS18805 4111099 4113556 - fimbrial assembly protein gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18805 AFK63_RS18810 AFK63_18830 AFK63_RS18810 4113566 4114273 - pilus assembly protein gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18810 AFK63_RS18815 AFK63_18835 AFK63_RS18815 4115650 4117728 - ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18815 AFK63_RS18820 AFK63_18840 AFK63_RS18820 4117732 4118421 - tRNA guanosine-2'-O-methyltransferase specifically modifies tRNA at position G18 gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18820 AFK63_RS18825 AFK63_18845 AFK63_RS18825 4118426 4120546 - (p)ppGpp synthetase gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18825 AFK63_RS18830 AFK63_18850 rpoZ rpoZ 4120566 4120841 - DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18830 AFK63_RS18835 AFK63_18855 gmk gmk 4120896 4121519 - guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18835 AFK63_RS18840 AFK63_18860 ligB ligB 4121778 4123478 + NAD-dependent DNA ligase LigB this ligase is similar to LigA but it lacks the C-terminal BRCT domain%3B catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18840 AFK63_RS18845 AFK63_18865 AFK63_RS18845 4123539 4124156 - membrane protein gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18845 AFK63_RS18850 AFK63_18870 AFK63_RS18850 4124364 4125227 - hypothetical protein gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18850 AFK63_RS18855 AFK63_18875 rph rph 4125353 4126069 + ribonuclease PH RNase PH%3B tRNA nucleotidyltransferase%3B forms hexamers in Bacillus subtilis%3B phosphoroltic 3'-5' exoribonuclease%3B involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18855 AFK63_RS18860 AFK63_18880 pyrE pyrE 4126134 4126775 + orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18860 AFK63_RS18865 AFK63_18885 slmA slmA 4126827 4127423 - division inhibitor protein FtsZ binding protein%3B synthetically lethal with a defect in the Min system%3B this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18865 AFK63_RS18870 AFK63_18890 AFK63_RS18870 4127550 4128008 - deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18870 AFK63_RS18875 AFK63_18895 AFK63_RS18875 4127986 4129197 - phosphopantothenoylcysteine decarboxylase catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18875 AFK63_RS18880 AFK63_18900 AFK63_RS18880 4129379 4130032 + hypothetical protein gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18880 AFK63_RS18885 AFK63_18905 rpmB rpmB 4130247 4130483 + 50S ribosomal protein L28 required for 70S ribosome assembly gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18885 AFK63_RS18890 AFK63_18910 rpmG rpmG 4130504 4130671 + 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18890 AFK63_RS18895 AFK63_18915 AFK63_RS18895 4130780 4131589 + formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18895 AFK63_RS18900 AFK63_18920 coaD coaD 4131590 4132069 - phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18900 AFK63_RS18905 AFK63_18925 AFK63_RS18905 4132074 4132841 - LPS biosynthesis protein gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18905 AFK63_RS18910 AFK63_18930 AFK63_RS18910 4132841 4134160 - 3-deoxy-D-manno-octulosonic acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18910 AFK63_RS18915 AFK63_18935 AFK63_RS18915 4134179 4134415 + hypothetical protein gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18915 AFK63_RS18920 AFK63_18940 AFK63_RS18920 4134412 4135395 - glycosyl transferase gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18920 AFK63_RS18925 AFK63_18945 AFK63_RS18925 4135723 4136829 + glycosyl transferase family 1 gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18925 AFK63_RS18930 AFK63_18950 AFK63_RS18930 4136808 4137917 - glycosyl transferase family 1 gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18930 AFK63_RS18935 AFK63_18955 AFK63_RS18935 4137914 4139017 - heptosyltransferase gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18935 AFK63_RS18940 AFK63_18960 AFK63_RS18940 4139010 4140011 - ADP-heptose--LPS heptosyltransferase gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18940 AFK63_RS18945 AFK63_18965 AFK63_RS18945 4140014 4141060 - ADP-heptose--LPS heptosyltransferase catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18945 AFK63_RS18950 AFK63_18970 rfaD rfaD 4141073 4142005 - ADP-L-glycero-D-manno-heptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18950 AFK63_RS18955 AFK63_18975 AFK63_RS18955 4142234 4143430 + 2-amino-3-ketobutyrate CoA ligase catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18955 AFK63_RS18960 AFK63_18980 tdh tdh 4143440 4144465 + L-threonine 3-dehydrogenase converts threonine and NAD to 1%2C2-amino-3-oxobutanoate and NADH%3B functions in threonine catabolism gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18960 AFK63_RS18965 AFK63_18985 AFK63_RS18965 4144690 4146270 + sulfatase gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18965 AFK63_RS18970 AFK63_18990 AFK63_RS18970 4146342 4147601 + polymerase gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18970 AFK63_RS18975 AFK63_18995 AFK63_RS18975 4147674 4148522 + family 2 glycosyl transferase gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18975 AFK63_RS18980 AFK63_19000 AFK63_RS18980 4148543 4149460 + capsular biosynthesis protein gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18980 AFK63_RS18985 AFK63_19005 AFK63_RS18985 4149527 4150465 - hypothetical protein gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18985 AFK63_RS18990 AFK63_19010 AFK63_RS18990 4150469 4151752 - AmiB activator gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18990 AFK63_RS18995 AFK63_19015 AFK63_RS18995 4151762 4153309 - phosphoglyceromutase catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS18995 AFK63_RS19000 AFK63_19020 AFK63_RS19000 4153552 4153983 + hypothetical protein gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19000 AFK63_RS19005 AFK63_19025 AFK63_RS19005 4154004 4154255 + glutaredoxin gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19005 AFK63_RS19010 AFK63_19030 AFK63_RS19010 4154310 4154777 + preprotein translocase subunit SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19010 AFK63_RS19015 AFK63_19035 AFK63_RS19015 4154777 4155796 + glycerol-3-phosphate dehydrogenase gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19015 AFK63_RS19020 AFK63_19040 cysE cysE 4155874 4156695 + serine acetyltransferase catalyzes the O-acetylation of serine gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19020 AFK63_RS19025 AFK63_19045 AFK63_RS19025 4156761 4157234 - rRNA methylase member of the SPOUT superfamily of RNA methyltransferases gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19025 AFK63_RS19030 AFK63_19050 cpxA cpxA 4157352 4158725 - two-component sensor protein part of two-component CpxA/CpxR system%3B senses envelope stress%3B upregulates a number of periplasmic folding and trafficking factors gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19030 AFK63_RS19035 AFK63_19055 AFK63_RS19035 4158722 4159420 - two-component system response regulator response regulator in two-component regulatory system with CpxA%3B part of the envelope stress response system gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19035 AFK63_RS19040 AFK63_19060 cpxP cpxP 4159569 4160075 + periplasmic repressor CpxP repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA%3B CpxP is degraded by DegP protease especially in the presence of misfolded substrates gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19040 AFK63_RS19045 AFK63_19065 fieF fieF 4160253 4161155 + ferrous iron transporter member of cation diffusion facilitator family%3B CDF%3B membrane-bound%3B induced by both zinc and iron%2C but does not induce resistance to zinc%3B can transport zinc(II) in a proton-dependent manner%3B instead this protein induces iron resistance%3B forms dimers gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19045 AFK63_RS19050 AFK63_19070 AFK63_RS19050 4161345 4162307 + ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19050 AFK63_RS19055 AFK63_19075 AFK63_RS19055 4162474 4163463 + sulfate transporter subunit gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19055 AFK63_RS19060 AFK63_19080 AFK63_RS19060 4163568 4164335 + CDP-diacylglycerol pyrophosphatase gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19060 AFK63_RS19065 AFK63_19085 AFK63_RS19065 4164394 4165698 + citrate transporter gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19065 AFK63_RS19070 AFK63_19090 AFK63_RS19070 4165722 4166114 + hypothetical protein gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19070 AFK63_RS19075 AFK63_19095 AFK63_RS19075 4166099 4166506 - hydroxyisourate hydrolase gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19075 AFK63_RS19080 AFK63_19100 AFK63_RS19080 4166642 4167322 + two-component system response regulator induced by CusR in the presence of copper%3B YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW%3B yedVW is one of four copper regulons found in E. coli%3B part of the copper homeostasis mechanism%3B confers resistance to copper and several drugs when induced gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19080 AFK63_RS19085 AFK63_19105 AFK63_RS19085 4167315 4168676 + two-component system sensor histidine kinase gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19085 AFK63_RS19090 AFK63_19110 AFK63_RS19090 4168683 4169333 - CAAX amino protease gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19090 AFK63_RS19095 AFK63_19115 AFK63_RS19095 4169460 4169864 - cupin gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19095 AFK63_RS19100 AFK63_19120 AFK63_RS19100 4169944 4170990 - zinc-binding dehydrogenase gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19100 AFK63_RS19105 AFK63_19125 AFK63_RS19105 4171025 4172227 - transcriptional regulator gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19105 AFK63_RS19110 AFK63_19130 AFK63_RS19110 4172494 4173396 + LysR family transcriptional regulator gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19110 AFK63_RS19115 AFK63_19135 AFK63_RS19115 4173401 4174450 - glycosyl transferase gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19115 AFK63_RS19120 AFK63_19140 AFK63_RS19120 4174646 4175221 + aldehyde oxidoreductase gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19120 AFK63_RS19125 AFK63_19145 AFK63_RS19125 4175218 4176171 + hypothetical protein gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19125 AFK63_RS19130 AFK63_19150 AFK63_RS19130 4176171 4178372 + xanthine dehydrogenase gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19130 AFK63_RS19135 AFK63_19155 AFK63_RS19135 4178444 4179388 + hypothetical protein gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19135 AFK63_RS19140 AFK63_19160 AFK63_RS19140 4179388 4179963 + molybdopterin-guanine dinucleotide biosynthesis protein MobA gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19140 AFK63_RS19145 AFK63_19165 AFK63_RS19145 4179997 4180863 - oxidoreductase gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19145 AFK63_RS19150 AFK63_19170 AFK63_RS19150 4180939 4181559 + TetR family transcriptional regulator gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19150 AFK63_RS19155 AFK63_19175 AFK63_RS19155 4181813 4182304 + type VI secretion system effector gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19155 AFK63_RS19160 AFK63_19180 AFK63_RS19160 4184208 4185131 + hypothetical protein gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19160 AFK63_RS19165 AFK63_RS19165 AFK63_RS19165 4185128 4185586 + hypothetical protein gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19165 AFK63_RS19170 AFK63_19190 AFK63_RS19170 4185918 4188251 - DNA primase gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19170 AFK63_RS19175 AFK63_19195 AFK63_RS19175 4188266 4188586 - hypothetical protein gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19175 AFK63_RS19180 AFK63_19200 AFK63_RS19180 4188583 4188810 - hypothetical protein gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19180 AFK63_RS19185 AFK63_RS19185 AFK63_RS19185 4188807 4189001 - Phage immunity repressor protein gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19185 AFK63_RS19190 AFK63_19210 AFK63_RS19190 4189355 4189621 - hypothetical protein gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19190 AFK63_RS19195 AFK63_19215 AFK63_RS19195 4190158 4190901 + phage capsid protein gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19195 AFK63_RS19200 AFK63_19220 AFK63_RS19200 4190904 4191122 + hypothetical protein gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19200 AFK63_RS19205 AFK63_19225 AFK63_RS19205 4191151 4191717 + Polarity suppression protein gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19205 AFK63_RS19210 AFK63_19230 AFK63_RS19210 4192235 4194238 - hypothetical protein gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19210 AFK63_RS19215 AFK63_19235 AFK63_RS19215 4194253 4195416 - integrase gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19215 AFK63_RS19220 AFK63_19240 AFK63_RS19220 4195579 4195673 - tRNA-Sec tRNA gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19220 AFK63_RS19225 AFK63_19245 AFK63_RS19225 4195964 4197367 + transporter may be involved in the transport of galactosides-pentoses-hexuronides gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19225 AFK63_RS19230 AFK63_19250 AFK63_RS19230 4197371 4199692 + alpha-glucosidase catalyzes the transfer of alpha-xylosyl residue gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19230 AFK63_RS19235 AFK63_19255 avtA avtA 4199746 4201002 - valine--pyruvate aminotransferase transaminase C%3B catalyzes transamination of alanine%2C valine%2C and 2-aminobutyrate with their respective 2-keto acids%3B also catalyzes terminal step in valine biosynthesis gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19235 AFK63_RS19240 AFK63_19260 malS malS 4201178 4203208 - alpha-amylase periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB%3B hydrolyzes alpha-(1%2C4) glycosidic linkages%3B contains internal disulfide bonds gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19240 AFK63_RS19245 AFK63_19265 AFK63_RS19245 4203781 4204350 + mannosyl-glycoprotein endo-beta-N-acetylglucosamidase gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19245 AFK63_RS19250 AFK63_19270 AFK63_RS19250 4204498 4205676 - XylR family transcriptional regulator gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19250 AFK63_RS19255 AFK63_19275 AFK63_RS19255 4205775 4206965 - sugar ABC transporter permease gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19255 AFK63_RS19260 AFK63_19280 AFK63_RS19260 4206943 4208484 - D-xylose ABC transporter%2C ATP-binding protein with XylFH is part of the high affinity xylose ABC transporter gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19260 AFK63_RS19265 AFK63_19285 xylF xylF 4208551 4209543 - D-xylose transporter subunit XylF periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19265 AFK63_RS19270 AFK63_19290 AFK63_RS19270 4209927 4211249 + xylose isomerase catalyzes the interconversion of D-xylose to D-xylulose gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19270 AFK63_RS19275 AFK63_19295 AFK63_RS19275 4211298 4212752 + xylulose kinase catalyzes the formation of D-xylulose-5-phosphate fro D-xylulose gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19275 AFK63_RS19280 AFK63_19300 AFK63_RS19280 4212876 4213418 + hydrolase gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19280 AFK63_RS19285 AFK63_19305 AFK63_RS19285 4213415 4214335 + AraC family transcriptional regulator gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19285 AFK63_RS19290 AFK63_19310 AFK63_RS19290 4214328 4215320 - acetyltransferase gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19290 AFK63_RS19295 AFK63_19315 AFK63_RS19295 4215507 4215818 + membrane protein gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19295 AFK63_RS19300 AFK63_19320 AFK63_RS19300 4215937 4216848 + glycine--tRNA ligase subunit alpha gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19300 AFK63_RS19305 AFK63_19325 AFK63_RS19305 4216858 4218927 + hypothetical protein gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19305 AFK63_RS19310 AFK63_19330 AFK63_RS19310 4219529 4219822 - transcriptional regulator gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19310 AFK63_RS19315 AFK63_19335 AFK63_RS19315 4220101 4223667 - urea carboxylase gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19315 AFK63_RS19320 AFK63_19340 AFK63_RS19320 4223742 4224377 - urea carboxylase gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19320 AFK63_RS19325 AFK63_19345 AFK63_RS19325 4224380 4225090 - urea carboxylase gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19325 AFK63_RS19330 AFK63_19350 AFK63_RS19330 4225105 4225920 - lauroyl acyltransferase gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19330 AFK63_RS19335 AFK63_19355 AFK63_RS19335 4225930 4226742 - lipid kinase gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19335 AFK63_RS19340 AFK63_19360 AFK63_RS19340 4226757 4227812 - lipid kinase gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19340 AFK63_RS19345 AFK63_19365 AFK63_RS19345 4228817 4229527 + hypothetical protein gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19345 AFK63_RS19350 AFK63_19370 AFK63_RS19350 4229572 4230549 - bifunctional glyoxylate/hydroxypyruvate reductase B catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19350 AFK63_RS19355 AFK63_19375 AFK63_RS19355 4230619 4231899 - MFS transporter gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19355 AFK63_RS19360 AFK63_19380 AFK63_RS19360 4232141 4233079 - 2-dehydro-3-deoxygluconokinase gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19360 AFK63_RS19365 AFK63_19385 AFK63_RS19365 4233082 4233831 - epimerase gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19365 AFK63_RS19370 AFK63_19390 AFK63_RS19370 4233944 4234963 - LacI family transcriptional regulator gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19370 AFK63_RS19375 AFK63_19395 AFK63_RS19375 4235175 4235813 + zinc/cadmium-binding protein gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19375 AFK63_RS19380 AFK63_19400 AFK63_RS19380 4235860 4236522 - membrane protein gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19380 AFK63_RS19385 AFK63_19405 AFK63_RS19385 4236702 4239035 + trimethylamine N-oxide reductase I catalytic subunit catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19385 AFK63_RS19390 AFK63_19410 AFK63_RS19390 4239004 4239444 - acetyltransferase gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19390 AFK63_RS19395 AFK63_19415 AFK63_RS19395 4239441 4240004 - DNA-3-methyladenine glycosidase gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19395 AFK63_RS19400 AFK63_19420 AFK63_RS19400 4240160 4240792 + lipase gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19400 AFK63_RS19405 AFK63_19425 AFK63_RS19405 4240949 4242151 + membrane protein gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19405 AFK63_RS19410 AFK63_19430 AFK63_RS19410 4242273 4242704 + organic hydroperoxide resistance protein gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19410 AFK63_RS19415 AFK63_19435 AFK63_RS19415 4242921 4244600 + phosphoethanolamine transferase catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19415 AFK63_RS19420 AFK63_19440 AFK63_RS19420 4244692 4244768 + tRNA-Pro tRNA gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19420 AFK63_RS19425 AFK63_19445 AFK63_RS19425 4244823 4245377 + hypothetical protein gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19425 AFK63_RS19430 AFK63_19450 AFK63_RS19430 4245960 4247567 + peptide ABC transporter substrate-binding protein DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19430 AFK63_RS19435 AFK63_19455 AFK63_RS19435 4247763 4248782 + peptide ABC transporter permease gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19435 AFK63_RS19440 AFK63_19460 AFK63_RS19440 4248792 4249694 + peptide transporter gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19440 AFK63_RS19445 AFK63_19465 dppD dppD 4249706 4250701 + dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19445 AFK63_RS19450 AFK63_19470 dppF dppF 4250688 4251701 + peptide ABC transporter ATP-binding protein Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19450 AFK63_RS19455 AFK63_19475 AFK63_RS19455 4251862 4253547 - membrane protein gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19455 AFK63_RS19460 AFK63_19480 AFK63_RS19460 4253540 4253737 - hypothetical protein gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19460 AFK63_RS19465 AFK63_19485 AFK63_RS19465 4253734 4255308 - cellulose biosynthesis protein BcsE required for cellulose biosynthesis gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19465 AFK63_RS19470 AFK63_19490 AFK63_RS19470 4255481 4255687 + hypothetical protein gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19470 AFK63_RS19475 AFK63_19495 AFK63_RS19475 4255684 4256418 + cell division protein gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19475 AFK63_RS19480 AFK63_19500 bcsA bcsA 4256415 4259033 + cellulose synthase polymerizes uridine 5'-diphosphate glucose to cellulose%3B acts with BcsB%2C BcsZ and BcsC in cellulose biosynthesis gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19480 AFK63_RS19485 AFK63_19505 AFK63_RS19485 4259086 4261476 + cellulose synthase binds the cellulose synthase activator%2C bis-(3'-5') cyclic diguanylic acid (c-di-GMP) gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19485 AFK63_RS19490 AFK63_19510 AFK63_RS19490 4261483 4262598 + endo-1%2C4-D-glucanase catalyzes the hydrolysis of 1%2C4-beta-D-glucosidic linkages in cellulose%2C lichenin and cereal beta-D-glucans gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19490 AFK63_RS19495 AFK63_19515 AFK63_RS19495 4262580 4266083 + cellulose synthase cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium%3B the cellulose biosynthesis genes bcsA%2C bcsB%2C bcsZ and bcsC are constitutively transcribed%2C however%2C cellulose synthesis is dependent on the expression of adrA gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19495 AFK63_RS19500 AFK63_19520 AFK63_RS19500 4266207 4268150 + biofilm formation regulator HmsP HmsP in Yersinia pestis plays a role in invasion of epithelial cells%3B the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation%3B inner membrane protein gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19500 AFK63_RS19505 AFK63_19525 AFK63_RS19505 4268331 4269617 + C4-dicarboxylate transporter involved in the transport of C4-dicarboxylates across the membrane gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19505 AFK63_RS19510 AFK63_19530 AFK63_RS19510 4269816 4271294 + hypothetical protein gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19510 AFK63_RS19515 AFK63_19535 AFK63_RS19515 4271401 4272333 - ketodeoxygluconokinase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19515 AFK63_RS19520 AFK63_19540 AFK63_RS19520 4272567 4273340 + c-di-GMP phosphodiesterase in Escherichia coli this protein is involved in flagellar function gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19520 AFK63_RS19525 AFK63_19545 AFK63_RS19525 4273405 4275462 + hypothetical protein gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19525 AFK63_RS19530 AFK63_19550 AFK63_RS19530 4275716 4277044 - transporter gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19530 AFK63_RS19535 AFK63_19555 AFK63_RS19535 4277319 4278353 - membrane protein gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19535 AFK63_RS19540 AFK63_19560 AFK63_RS19540 4278406 4279305 - transcriptional regulator gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19540 AFK63_RS19545 AFK63_19565 AFK63_RS19545 4279424 4280182 + short-chain dehydrogenase gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19545 AFK63_RS19550 AFK63_19570 AFK63_RS19550 4280228 4280626 - periplasmic protein gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19550 AFK63_RS19555 AFK63_19575 AFK63_RS19555 4280739 4281314 - GCN5 family acetyltransferase gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19555 AFK63_RS19560 AFK63_19580 AFK63_RS19560 4281348 4281527 + hypothetical protein gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19560 AFK63_RS19565 AFK63_19585 AFK63_RS19565 4281586 4283190 + membrane protein gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19565 AFK63_RS19570 AFK63_19590 AFK63_RS19570 4283270 4284622 - glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19570 AFK63_RS19575 AFK63_19595 AFK63_RS19575 4284697 4285539 - ribosomal RNA large subunit methyltransferase J gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19575 AFK63_RS19580 AFK63_19600 AFK63_RS19580 4285733 4287775 + oligopeptidase A gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19580 AFK63_RS19585 AFK63_19605 AFK63_RS19585 4287784 4288536 + methyltransferase predicted SAM-dependent methyltransferase gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19585 AFK63_RS19590 AFK63_19610 AFK63_RS19590 4288603 4288878 - addiction module antitoxin gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19590 AFK63_RS19595 AFK63_19615 AFK63_RS19595 4288878 4289069 - stability determinant gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19595 AFK63_RS19600 AFK63_19620 AFK63_RS19600 4289243 4289680 - universal stress protein A involved in resistance to DNA-damaging agents gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19600 AFK63_RS19605 AFK63_19625 AFK63_RS19605 4290076 4290411 + universal stress protein B ppGpp-dependent%2C membrane associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19605 AFK63_RS19610 AFK63_19630 AFK63_RS19610 4290462 4291964 - phosphate transporter PitA involved in the transport of inorganic phosphate gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19610 AFK63_RS19615 AFK63_19635 AFK63_RS19615 4292194 4293384 + membrane protein gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19615 AFK63_RS19620 AFK63_19640 AFK63_RS19620 4293391 4294038 - alpha%2Calpha-trehalose-phosphate synthase gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19620 AFK63_RS19625 AFK63_19645 AFK63_RS19625 4294825 4296240 - gamma-glutamylputrescine synthetase gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19625 AFK63_RS19630 AFK63_19650 AFK63_RS19630 4296545 4297051 + lipoprotein gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19630 AFK63_RS19635 AFK63_19655 AFK63_RS19635 4297057 4298115 - permease gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19635 AFK63_RS19640 AFK63_19660 AFK63_RS19640 4298263 4299453 + MFS transporter gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19640 AFK63_RS19645 AFK63_19665 AFK63_RS19645 4299493 4300050 - hypothetical protein gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19645 AFK63_RS19650 AFK63_19670 AFK63_RS19650 4300124 4300789 - hypothetical protein gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19650 AFK63_RS19655 AFK63_19675 AFK63_RS19655 4300996 4301241 + sulfur transfer protein SirA TusA%3B transfers sulfur to TusBCD complex%3B involved in thiouridation of U34 position of some tRNAs gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19655 AFK63_RS19660 AFK63_19680 AFK63_RS19660 4301427 4302410 + C4-dicarboxylate ABC transporter gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19660 AFK63_RS19665 AFK63_19685 AFK63_RS19665 4302459 4302968 + C4-dicarboxylate ABC transporter gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19665 AFK63_RS19670 AFK63_19690 AFK63_RS19670 4302980 4304266 + membrane protein gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19670 AFK63_RS19675 AFK63_19695 zntA zntA 4304399 4306612 - zinc ABC transporter ATPase P-type ATPase involved in the export of lead%2C cadmium%2C zinc and mercury gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19675 AFK63_RS19680 AFK63_19700 AFK63_RS19680 4306713 4307339 - membrane protein gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19680 AFK63_RS19685 AFK63_19705 AFK63_RS19685 4307480 4307845 + hypothetical protein gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19685 AFK63_RS19690 AFK63_19710 AFK63_RS19690 4307896 4308165 - membrane protein gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19690 AFK63_RS19695 AFK63_19715 rsmD rsmD 4308155 4308751 - 16S rRNA methyltransferase catalyzes the methylation of 16S rRNA at position G966 gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19695 AFK63_RS19700 AFK63_19720 AFK63_RS19700 4308941 4310551 + signal recognition particle-docking protein FtsY cell division protein%3B signal recognition protein receptor%3B functions in the targeting and insertion of membrane proteins gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19700 AFK63_RS19705 AFK63_19725 AFK63_RS19705 4310554 4311222 + cell division protein FtsE ATP-binding protein of an ATP-binding cassette transporter%3B when bound to FtsX%2C FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19705 AFK63_RS19710 AFK63_19730 ftsX ftsX 4311215 4312270 + cell division protein FtsX ABC transporter%2C membrane protein gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19710 AFK63_RS19715 AFK63_19735 AFK63_RS19715 4312532 4313389 + RNA polymerase sigma factor RpoH binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19715 AFK63_RS19720 AFK63_19740 AFK63_RS19720 4313435 4314928 - decarboxylase gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19720 AFK63_RS19725 AFK63_19745 AFK63_RS19725 4315047 4316312 + 4-aminobutyrate aminotransferase catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19725 AFK63_RS19730 AFK63_19750 AFK63_RS19730 4316634 4317875 + amino acid permease gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19730 AFK63_RS19735 AFK63_19755 AFK63_RS19735 4318111 4319229 + leucine ABC transporter substrate-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19735 AFK63_RS19740 AFK63_19760 AFK63_RS19740 4319463 4319855 - hypothetical protein gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19740 AFK63_RS19745 AFK63_19765 AFK63_RS19745 4320276 4320533 + amino acid-binding protein gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19745 AFK63_RS19750 AFK63_19770 AFK63_RS19750 4320598 4321524 + branched-chain amino acid transporter permease subunit LivH LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19750 AFK63_RS19755 AFK63_19775 livM livM 4321521 4322801 + leucine/isoleucine/valine transporter permease subunit Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19755 AFK63_RS19760 AFK63_19780 livG livG 4322798 4323565 + leucine/isoleucine/valine transporter ATP-binding subunit Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19760 AFK63_RS19765 AFK63_19785 livF livF 4323567 4324280 + leucine/isoleucine/valine transporter ATP-binding subunit with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19765 AFK63_RS19770 AFK63_19790 AFK63_RS19770 4324413 4324634 + prevent host death protein Phd antitoxin gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19770 AFK63_RS19775 AFK63_19795 AFK63_RS19775 4324634 4325002 + death-on-curing family protein gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19775 AFK63_RS19780 AFK63_19800 AFK63_RS19780 4325173 4326492 + glycerol-3-phosphate ABC transporter substrate-binding protein with UgpACE is involved in the uptake of glycerol-3-phosphate gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19780 AFK63_RS19785 AFK63_19805 AFK63_RS19785 4326709 4327596 + glycerol-3-phosphate transporter permease with UgpEC is involved in the uptake of glycerol-3-phosphate gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19785 AFK63_RS19790 AFK63_19810 AFK63_RS19790 4327593 4328438 + glycerol-3-phosphate transporter membrane protein with UgpABC is involved in uptake of glycerol-3-phosphate gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19790 AFK63_RS19795 AFK63_19815 ugpC ugpC 4328440 4329513 + glycerol-3-phosphate transporter ATP-binding subunit part of the UgpABCE glycerol-3-phosphate uptake system gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19795 AFK63_RS19800 AFK63_19820 ugpQ ugpQ 4329510 4330250 + glycerophosphodiester phosphodiesterase hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol%3B induced when cells are starved for inorganic phosphate gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19800 AFK63_RS19805 AFK63_19825 AFK63_RS19805 4330247 4330723 - hypothetical protein gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19805 AFK63_RS19810 AFK63_19830 ggt ggt 4330853 4332610 + gamma-glutamyltranspeptidase periplasmic enzyme%3B post-translationally processed into two subunits which are required for wild-type enzyme activity%3B cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19810 AFK63_RS19815 AFK63_19835 AFK63_RS19815 4332728 4333225 - acetyltransferase gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19815 AFK63_RS19820 AFK63_19840 AFK63_RS19820 4333499 4334539 + oxidoreductase gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19820 AFK63_RS19825 AFK63_19845 AFK63_RS19825 4334661 4335356 + quercetin 2%2C3-dioxygenase gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19825 AFK63_RS19830 AFK63_19850 AFK63_RS19830 4335461 4336456 + transcriptional regulator gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19830 AFK63_RS19835 AFK63_19855 gntK gntK 4336598 4337125 + gluconate kinase thermoresistant%3B catalyzes the formation of 6-phospho-D-gluconate from gluconate gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19835 AFK63_RS19840 AFK63_19860 AFK63_RS19840 4337129 4338469 + gluconate transporter gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19840 AFK63_RS19845 AFK63_19865 AFK63_RS19845 4338572 4339165 - antibiotic transporter gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19845 AFK63_RS19850 AFK63_19870 AFK63_RS19850 4339335 4340441 + aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19850 AFK63_RS19855 AFK63_19875 AFK63_RS19855 4340700 4342895 + glycogen branching protein gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19855 AFK63_RS19860 AFK63_19880 AFK63_RS19860 4342882 4344864 + glycogen debranching protein catalyzes the hydrolysis of the alpha-1%2C6-glucosidic linkages in partially depolymerized glycogen gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19860 AFK63_RS19865 AFK63_19885 glgC glgC 4344878 4346161 + glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19865 AFK63_RS19870 AFK63_19890 glgA glgA 4346259 4347692 + glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19870 AFK63_RS19875 AFK63_19895 AFK63_RS19875 4347705 4350152 + maltodextrin phosphorylase gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19875 AFK63_RS19880 AFK63_19900 AFK63_RS19880 4350221 4350676 + hypothetical protein gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19880 AFK63_RS19885 AFK63_19905 AFK63_RS19885 4350684 4352243 - cellulose synthase gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19885 AFK63_RS19890 AFK63_19910 glpD glpD 4352389 4353906 - glycerol-3-phosphate dehydrogenase in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions%3B anaerobic expression is repressed by the arcAB system%3B converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8%3B associates with the cytoplasmic membrane gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19890 AFK63_RS19895 AFK63_19915 glpE glpE 4354131 4354460 + thiosulfate sulfurtransferase belongs to rhodanese family%3B thiosulfate thiotransferase%3B in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency%3B contains an active site cysteine gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19895 AFK63_RS19900 AFK63_19920 AFK63_RS19900 4354541 4355371 + intramembrane serine protease GlpG protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19900 AFK63_RS19905 AFK63_19925 AFK63_RS19905 4355397 4356155 + transcriptional regulator represses the glpD%2C glpFK%2C glpTQ%2C and glpACB operons involved in glycerol-3-phosphate metabolism gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19905 AFK63_RS19910 AFK63_19930 AFK63_RS19910 4356307 4359012 - transcriptional regulator MalT Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19910 AFK63_RS19915 AFK63_19935 AFK63_RS19915 4359626 4362028 + maltose phosphorylase gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19915 AFK63_RS19920 AFK63_RS19920 AFK63_RS19920 3526449 3526825 - bacterial RNase P ncRNA gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=AFK63_RS19920